# emapper version: emapper-2.0.1b-2-g816e190 emapper DB: 2.0 # command: ./emapper.py -i Lactobacillus_plantarum/1.contigAnn/FFN/A00000447.ffn --translate --temp_dir Lactobacillus_plantarum/4.eggNOG_mapper --output_dir Lactobacillus_plantarum/4.eggNOG_mapper --output A00000447 --cpu 36 --keep_mapping_files -m diamond # time: Mon Jun 27 17:49:28 2022 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction taxonomic scope eggNOG OGs best eggNOG OG COG Functional cat. eggNOG free text desc. PGHMIELC_00001 220668.lp_0047 2.9e-219 767.7 Lactobacillaceae calB 1.2.1.68 ko:K00154 ko00000,ko01000 Bacteria 1TP4S@1239,3F47F@33958,4H9MF@91061,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family PGHMIELC_00002 220668.lp_0048 1.8e-121 441.8 Lactobacillaceae ung2 3.2.2.27 ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1F8@1239,3F4WH@33958,4HFVS@91061,COG1573@1,COG1573@2 NA|NA|NA L Uracil-DNA glycosylase PGHMIELC_00003 220668.lp_0050 9.1e-121 439.5 Lactobacillaceae pnb Bacteria 1V6AG@1239,3F6YM@33958,4HN5N@91061,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase PGHMIELC_00004 60520.HR47_05825 2.6e-64 251.1 Lactobacillaceae queD 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1VEAX@1239,3F7HK@33958,4HZ0J@91061,COG0720@1,COG0720@2 NA|NA|NA H 6-pyruvoyl tetrahydropterin synthase PGHMIELC_00005 220668.lp_0053 5.7e-115 420.2 Lactobacillaceae Bacteria 1V4P1@1239,2C009@1,32UHI@2,3F5IU@33958,4HH50@91061 NA|NA|NA S Elongation factor G-binding protein, N-terminal PGHMIELC_00006 220668.lp_0055 0.0 1593.6 Lactobacillaceae nqr 1.3.5.4,1.5.1.36 ko:K00244,ko:K22393 ko00020,ko00190,ko00620,ko00650,ko00720,ko00740,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map00740,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164,R05705,R09748,R09750 RC00045,RC00126 ko00000,ko00001,ko00002,ko01000 Bacteria 1UZHI@1239,3F4A4@33958,4I3MZ@91061,COG0431@1,COG0431@2,COG1053@1,COG1053@2,COG3976@1,COG3976@2 NA|NA|NA C FMN_bind PGHMIELC_00007 220668.lp_0056 2.9e-257 894.0 Lactobacillaceae ko:K03319 ko00000 2.A.47 Bacteria 1TSGE@1239,3F4RH@33958,4HDE4@91061,COG0471@1,COG0471@2 NA|NA|NA P Sodium:sulfate symporter transmembrane region PGHMIELC_00008 220668.lp_0057 2.4e-78 298.1 Lactobacillaceae Bacteria 1V5VW@1239,3F5D2@33958,4HHDY@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR family PGHMIELC_00009 220668.lp_0057 7.3e-65 253.1 Lactobacillaceae Bacteria 1V5VW@1239,3F5D2@33958,4HHDY@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR family PGHMIELC_00010 220668.lp_0058 1.1e-71 275.8 Lactobacillaceae Bacteria 1VCK0@1239,3F6FQ@33958,4I1W9@91061,COG0716@1,COG0716@2 NA|NA|NA C FMN binding PGHMIELC_00011 220668.lp_0059 3.2e-74 284.3 Lactobacillaceae arsC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 ko:K03741 ko00000,ko01000 Bacteria 1V3JW@1239,3F6GQ@33958,4HH49@91061,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family PGHMIELC_00012 220668.lp_0060 2e-163 581.6 Lactobacillaceae ptlF Bacteria 1UI5T@1239,3FBSB@33958,4HI5J@91061,COG4221@1,COG4221@2 NA|NA|NA S KR domain PGHMIELC_00013 220668.lp_0061 7.1e-158 563.1 Lactobacillaceae adc 4.1.1.4 ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 M00088 R01366 RC00040 ko00000,ko00001,ko00002,ko01000 Bacteria 1VW7Z@1239,3F5RQ@33958,4I17W@91061,COG4689@1,COG4689@2 NA|NA|NA Q Acetoacetate decarboxylase (ADC) PGHMIELC_00014 220668.lp_0062 1.3e-122 445.7 Lactobacillaceae drgA Bacteria 1UYJU@1239,3F4H1@33958,4HBVQ@91061,COG0778@1,COG0778@2 NA|NA|NA C Nitroreductase family PGHMIELC_00015 220668.lp_0063 6.4e-290 1002.7 Lactobacillaceae ko:K09684 ko00000,ko03000 Bacteria 1TRRH@1239,3F5KD@33958,4HQKK@91061,COG2508@1,COG2508@2 NA|NA|NA QT PucR C-terminal helix-turn-helix domain PGHMIELC_00016 220668.lp_0066 2.7e-120 438.0 Lactobacillaceae pgmB GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008801,GO:0009058,GO:0009292,GO:0009294,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016853,GO:0016866,GO:0016868,GO:0019203,GO:0030312,GO:0033554,GO:0034637,GO:0040007,GO:0042221,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046351,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0071704,GO:0071944,GO:1901576 2.4.1.64,3.1.3.12,3.2.1.28,5.4.2.6 ko:K01087,ko:K01194,ko:K01838,ko:K05342 ko00500,ko01100,map00500,map01100 R00010,R02727,R02728,R02778,R11310 RC00017,RC00049,RC00408 ko00000,ko00001,ko00537,ko01000 GH37,GH65 Bacteria 1UY8N@1239,3F4ST@33958,4HF3K@91061,COG0637@1,COG0637@2 NA|NA|NA S beta-phosphoglucomutase PGHMIELC_00017 220668.lp_0067 6e-196 689.9 Lactobacillaceae pva1 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 1TPZS@1239,3F4NH@33958,4HC4Y@91061,COG3049@1,COG3049@2 NA|NA|NA M Linear amide C-N hydrolase, choloylglycine hydrolase family protein PGHMIELC_00018 220668.lp_0068 1.6e-249 868.2 Lactobacillaceae yjjP Bacteria 1TNZH@1239,3F4FR@33958,4HU4D@91061,COG2966@1,COG2966@2,COG3610@1,COG3610@2 NA|NA|NA S Putative threonine/serine exporter PGHMIELC_00019 220668.lp_0069 5.7e-135 486.9 Lactobacillaceae wzb 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1V6Q5@1239,3F5X1@33958,4HJKY@91061,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family PGHMIELC_00020 60520.HR47_05895 1.4e-254 885.2 Lactobacillaceae 1.14.14.9 ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 R02698,R03299 RC00046 ko00000,ko00001,ko01000 Bacteria 1TQ70@1239,3F5BC@33958,4HA4I@91061,COG2368@1,COG2368@2 NA|NA|NA Q 4-hydroxyphenylacetate PGHMIELC_00021 220668.lp_0072 2.9e-81 307.8 Lactobacillaceae 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 Bacteria 1V6S0@1239,3F7EV@33958,4HKKR@91061,COG4405@1,COG4405@2 NA|NA|NA S ASCH PGHMIELC_00022 220668.lp_0073 4.2e-129 467.2 Lactobacillaceae yfeJ 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1UAH0@1239,3F4AV@33958,4HHTX@91061,COG0518@1,COG0518@2 NA|NA|NA F glutamine amidotransferase PGHMIELC_00023 220668.lp_0074 2e-169 601.7 Lactobacillaceae yobV1 Bacteria 1U8E4@1239,3FBID@33958,4IQQI@91061,COG2378@1,COG2378@2 NA|NA|NA K WYL domain PGHMIELC_00024 220668.lp_0075 3.6e-117 427.6 Lactobacillaceae azoR GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008081,GO:0008150,GO:0008152,GO:0008770,GO:0009987,GO:0016787,GO:0016788,GO:0019752,GO:0032787,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704,GO:0140096 ko:K01118 ko00000,ko01000 Bacteria 1V2AQ@1239,3F580@33958,4HGK5@91061,COG1182@1,COG1182@2 NA|NA|NA C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity PGHMIELC_00025 220668.lp_0076 0.0 1339.3 Lactobacillaceae tetP ko:K02355 ko00000,ko03012,ko03029 Bacteria 1TPQH@1239,3F4B4@33958,4HAS9@91061,COG0480@1,COG0480@2 NA|NA|NA J elongation factor G PGHMIELC_00026 220668.lp_0077 1.2e-45 188.7 Lactobacillaceae Bacteria 1V2CT@1239,28P7V@1,2ZC22@2,3F6CH@33958,4HG6A@91061 NA|NA|NA S Protein of unknown function PGHMIELC_00027 220668.lp_0077 1.4e-62 245.4 Lactobacillaceae Bacteria 1V2CT@1239,28P7V@1,2ZC22@2,3F6CH@33958,4HG6A@91061 NA|NA|NA S Protein of unknown function PGHMIELC_00028 220668.lp_0078 2.8e-152 544.7 Lactobacillaceae Bacteria 1V23Q@1239,3FBA3@33958,4HDPS@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family PGHMIELC_00029 220668.lp_0080 3.6e-93 347.4 Lactobacillaceae MA20_25245 Bacteria 1VEEJ@1239,3FBDP@33958,4HP6M@91061,COG0454@1,COG0456@2 NA|NA|NA K FR47-like protein PGHMIELC_00030 220668.lp_0081 2e-126 458.4 Lactobacillaceae hchA Bacteria 1UG8E@1239,3F4SD@33958,4HCBM@91061,COG0693@1,COG0693@2 NA|NA|NA S DJ-1/PfpI family PGHMIELC_00031 220668.lp_0082 5.2e-184 650.2 Lactobacillaceae GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0007275,GO:0007399,GO:0008150,GO:0009987,GO:0010975,GO:0016020,GO:0019867,GO:0022008,GO:0030154,GO:0031090,GO:0031344,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032501,GO:0032502,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045595,GO:0045664,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050773,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051239,GO:0051960,GO:0060284,GO:0065007,GO:0098588,GO:0098805,GO:0120035,GO:2000026 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1TQ0M@1239,3F4EJ@33958,4HA8M@91061,COG0604@1,COG0604@2 NA|NA|NA C nadph quinone reductase PGHMIELC_00032 220668.lp_0083 9.3e-50 202.6 Lactobacillaceae ko:K03892 ko00000,ko03000 Bacteria 1VFY4@1239,3FB52@33958,4HP5T@91061,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor PGHMIELC_00033 220668.lp_0085 8.7e-235 819.3 Lactobacillaceae mepA ko:K18908 M00705 ko00000,ko00002,ko01504,ko02000 2.A.66.1.13 Bacteria 1TPFM@1239,3F3KX@33958,4HEHY@91061,COG0534@1,COG0534@2 NA|NA|NA V MATE efflux family protein PGHMIELC_00034 220668.lp_0088 1.8e-169 601.7 Lactobacillaceae pepI 3.4.11.5,3.5.1.101 ko:K01259,ko:K18457 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 1TRMT@1239,3F40N@33958,4HE23@91061,COG2267@1,COG2267@2 NA|NA|NA E Releases the N-terminal proline from various substrates PGHMIELC_00035 220668.lp_0089 1.6e-140 505.4 Lactobacillaceae ko:K09861 ko00000 Bacteria 1TR33@1239,3F4KR@33958,4HFN2@91061,COG3022@1,COG3022@2 NA|NA|NA S Belongs to the UPF0246 family PGHMIELC_00036 220668.lp_0091 6e-76 290.0 Lactobacillaceae Bacteria 1U501@1239,2A775@1,30W3A@2,3F6AF@33958,4IKCQ@91061 NA|NA|NA PGHMIELC_00037 220668.lp_0092 0.0 1078.5 Lactobacillaceae oppA ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F46R@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E Bacterial extracellular solute-binding proteins, family 5 Middle PGHMIELC_00038 220668.lp_0096 2.4e-141 508.1 Lactobacillaceae Bacteria 1U555@1239,29NK9@1,309I8@2,3F4QT@33958,4IEWG@91061 NA|NA|NA PGHMIELC_00040 220668.lp_0098 1.8e-144 518.5 Lactobacillaceae 2.7.7.47 ko:K00984 ko00000,ko01000,ko01504 Bacteria 1UCIC@1239,3F5YN@33958,4HEP7@91061,COG1708@1,COG1708@2 NA|NA|NA H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin PGHMIELC_00041 220668.lp_0099 4.8e-40 169.9 Lactobacillaceae Bacteria 1U6BN@1239,2BWF7@1,30A8B@2,3F7J1@33958,4IG3A@91061 NA|NA|NA PGHMIELC_00042 220668.lp_0100 2.1e-129 468.4 Lactobacillaceae cbiO GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K02006 ko02010,map02010 M00245,M00246 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 Bacteria 1V16T@1239,3F5BR@33958,4HI15@91061,COG1122@1,COG1122@2 NA|NA|NA P ABC transporter PGHMIELC_00043 220668.lp_0101 3.1e-150 537.7 Lactobacillaceae ko:K02008 ko02010,map02010 M00245,M00246 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 Bacteria 1V7YC@1239,3F6UF@33958,4HRFQ@91061,COG0619@1,COG0619@2 NA|NA|NA P Cobalt transport protein PGHMIELC_00044 220668.lp_0102 4.8e-182 643.7 Lactobacillaceae nikMN GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K02007 ko02010,map02010 M00245,M00246 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 Bacteria 1TPEN@1239,3F4V7@33958,4IRCD@91061,COG0310@1,COG0310@2 NA|NA|NA P PDGLE domain PGHMIELC_00045 220668.lp_0103 4.2e-121 440.7 Lactobacillaceae ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 Bacteria 1UXDW@1239,3F5KR@33958,4HCRG@91061,COG0664@1,COG0664@2 NA|NA|NA K Crp-like helix-turn-helix domain PGHMIELC_00046 60520.HR47_06030 1e-240 839.0 Lactobacillaceae larA 5.1.2.1 ko:K22373 ko00620,map00620 R01450 RC00519 ko00000,ko00001,ko01000 Bacteria 1TQ1C@1239,3F3MP@33958,4HDCE@91061,COG3875@1,COG3875@2 NA|NA|NA S Domain of unknown function (DUF2088) PGHMIELC_00047 220668.lp_0105 2.4e-125 454.9 Lactobacillaceae larB ko:K06898 ko00000 Bacteria 1TP0Z@1239,3F526@33958,4HBMK@91061,COG1691@1,COG1691@2 NA|NA|NA S AIR carboxylase PGHMIELC_00048 220668.lp_0106 6.3e-132 476.9 Lactobacillaceae larC 4.99.1.12 ko:K06898,ko:K09121 ko00000,ko01000 Bacteria 1TPAV@1239,3F408@33958,4HC7I@91061,COG1641@1,COG1641@2 NA|NA|NA S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes PGHMIELC_00049 220668.lp_0107 5e-75 287.0 Lactobacillaceae larC 4.99.1.12 ko:K06898,ko:K09121 ko00000,ko01000 Bacteria 1V4CM@1239,3F6BC@33958,4IBXK@91061,COG1641@1,COG1641@2 NA|NA|NA S Protein of unknown function DUF111 PGHMIELC_00050 220668.lp_0108 1.5e-132 478.8 Lactobacillaceae glpF ko:K02440 ko00000,ko02000 1.A.8.1,1.A.8.2 Bacteria 1TP4T@1239,3F4Y7@33958,4HAWP@91061,COG0580@1,COG0580@2 NA|NA|NA U Belongs to the MIP aquaporin (TC 1.A.8) family PGHMIELC_00051 220668.lp_0109 1.1e-150 539.3 Lactobacillaceae larE ko:K06864 ko00000 Bacteria 1TPB2@1239,3F3Z9@33958,4HAZT@91061,COG1606@1,COG1606@2 NA|NA|NA S NAD synthase PGHMIELC_00052 220668.lp_0111 1e-176 625.9 Lactobacillaceae 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 1TZGF@1239,3FC43@33958,4HEDQ@91061,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase PGHMIELC_00053 220668.lp_0113 2e-138 498.4 Lactobacillaceae thiM GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008972,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V1R6@1239,3F43J@33958,4HFTJ@91061,COG2145@1,COG2145@2 NA|NA|NA H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) PGHMIELC_00054 220668.lp_0114 3.2e-147 527.7 Lactobacillaceae thiD GO:0008150,GO:0040007 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 ko:K00941,ko:K03147,ko:K21219 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R03472,R04509,R10712 RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ4A@1239,3F3NA@33958,4HAAH@91061,COG0351@1,COG0351@2 NA|NA|NA H Phosphomethylpyrimidine kinase PGHMIELC_00055 220668.lp_0115 5.6e-110 403.7 Lactobacillaceae thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3ZR@1239,3F5ZQ@33958,4HH1E@91061,COG0352@1,COG0352@2 NA|NA|NA H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) PGHMIELC_00056 220668.lp_0116 1.3e-208 732.3 Lactobacillaceae cytX ko:K03457 ko00000 2.A.39 Bacteria 1TTBN@1239,3F4YG@33958,4HA3B@91061,COG1457@1,COG1457@2 NA|NA|NA U Belongs to the purine-cytosine permease (2.A.39) family PGHMIELC_00057 220668.lp_0117 1.6e-137 495.4 Lactobacillaceae ko:K07010 ko00000,ko01002 Bacteria 1V1KC@1239,3F4PK@33958,4HI59@91061,COG2071@1,COG2071@2 NA|NA|NA S peptidase C26 PGHMIELC_00058 220668.lp_0118 7.3e-305 1052.4 Lactobacillaceae Bacteria 1UGIJ@1239,29VC1@1,30GSE@2,3F5VP@33958,4IF7C@91061 NA|NA|NA L HIRAN domain PGHMIELC_00059 220668.lp_0119 3.4e-85 320.9 Lactobacillaceae Bacteria 1V3T8@1239,3FC6R@33958,4HH2F@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain PGHMIELC_00060 220668.lp_0120 2.6e-250 870.9 Lactobacillaceae yifK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03293 ko00000 2.A.3.1 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease PGHMIELC_00061 220668.lp_0121 2.4e-122 444.9 Lactobacillaceae Bacteria 1U5V7@1239,29NYS@1,309WV@2,3F6J8@33958,4IFIU@91061 NA|NA|NA PGHMIELC_00062 220668.lp_0122 1.1e-149 535.8 Bacilli ydjP Bacteria 1UIX9@1239,4ISVM@91061,COG2267@1,COG2267@2 NA|NA|NA I Alpha/beta hydrolase family PGHMIELC_00063 60520.HR47_06115 0.0 1663.7 Lactobacillaceae pacL1 Bacteria 1TPF5@1239,3F3KP@33958,4H9S5@91061,COG0474@1,COG0474@2 NA|NA|NA P P-type ATPase PGHMIELC_00064 220668.lp_0125 1.6e-140 505.4 Lactobacillaceae 2.4.2.3 ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01876,R02484,R08229 RC00063 ko00000,ko00001,ko01000 Bacteria 1V6T2@1239,3FBN9@33958,4HCSE@91061,COG2820@1,COG2820@2 NA|NA|NA F Phosphorylase superfamily PGHMIELC_00065 220668.lp_0126 1.6e-28 131.3 Lactobacillaceae ko:K03973 ko00000,ko02048,ko03000 Bacteria 1VKBQ@1239,3F8BW@33958,4HRGW@91061,COG1983@1,COG1983@2 NA|NA|NA KT PspC domain PGHMIELC_00066 220668.lp_0127 7.2e-112 409.8 Lactobacillaceae ko:K19784 ko00000 Bacteria 1VI8F@1239,3F66U@33958,4HPT0@91061,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase PGHMIELC_00067 220668.lp_0128 1.2e-74 285.8 Lactobacillaceae papX3 Bacteria 1U5QT@1239,3F6BV@33958,4IFEV@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator PGHMIELC_00068 60520.HR47_06140 1.7e-72 278.5 Lactobacillaceae hsp1 ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 1VG0E@1239,3F7DR@33958,4HPDH@91061,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family PGHMIELC_00069 220668.lp_0130 8.7e-30 135.6 Lactobacillaceae Bacteria 1VC1H@1239,2AH77@1,330UE@2,3FC0W@33958,4HNZ6@91061 NA|NA|NA S Protein of unknown function (DUF3021) PGHMIELC_00070 220668.lp_0131 1.1e-74 285.8 Lactobacillaceae Bacteria 1U6J0@1239,3F80K@33958,4IGBI@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain PGHMIELC_00071 220668.lp_0132 4.7e-227 793.5 Lactobacillaceae mdtG GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085 ko:K08161 ko00000,ko02000 2.A.1.2.20 Bacteria 1TRDJ@1239,3F3T5@33958,4H9Q9@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_00072 220668.lp_0133 5e-51 206.8 Lactobacillaceae cadC1 Bacteria 1VF0J@1239,3F8E3@33958,4HP0R@91061,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor PGHMIELC_00073 220668.lp_0134 8.1e-216 756.1 Lactobacillaceae yeaN GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 ko:K03449 ko00000,ko02000 2.A.1.17 Bacteria 1TP9R@1239,3F52B@33958,4H9YZ@91061,COG2807@1,COG2807@2 NA|NA|NA P Transporter, major facilitator family protein PGHMIELC_00075 220668.lp_0136 3.4e-160 570.9 Lactobacillaceae Bacteria 1TPM1@1239,3FB4S@33958,4HAG6@91061,COG0656@1,COG0656@2 NA|NA|NA S reductase PGHMIELC_00076 220668.lp_0137 6.2e-165 586.6 Lactobacillaceae 1.1.1.65 ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 R01708 RC00116 ko00000,ko00001,ko01000 Bacteria 1UYMV@1239,3F4I8@33958,4HE0W@91061,COG0667@1,COG0667@2 NA|NA|NA C Aldo keto reductase PGHMIELC_00077 220668.lp_0138 1.3e-81 308.9 Lactobacillaceae 2.4.2.6 ko:K08728 ko00240,map00240 R02806 RC00063 ko00000,ko00001,ko01000 Bacteria 1U57V@1239,3F51W@33958,4IEZ3@91061,COG3613@1,COG3613@2 NA|NA|NA F Nucleoside 2-deoxyribosyltransferase like PGHMIELC_00078 220668.lp_0139 0.0 1149.4 Lactobacillaceae lai 4.2.1.53 ko:K10254 ko00000,ko01000 Bacteria 1TQZ6@1239,3F3QX@33958,4HAYH@91061,COG4716@1,COG4716@2 NA|NA|NA S Myosin-crossreactive antigen PGHMIELC_00079 220668.lp_0141 5e-52 211.5 Lactobacillaceae Bacteria 1U6D8@1239,29PBE@1,30A9N@2,3F7N7@33958,4IG4Z@91061 NA|NA|NA PGHMIELC_00080 220668.lp_0145 7.5e-259 899.4 Lactobacillaceae Bacteria 1U571@1239,29NM1@1,309J0@2,3F4ZQ@33958,4IEYJ@91061 NA|NA|NA PGHMIELC_00081 220668.lp_0146 2.6e-208 731.1 Lactobacillaceae Bacteria 1TPM6@1239,3F3UQ@33958,4HAS5@91061,COG1902@1,COG1902@2 NA|NA|NA C Oxidoreductase PGHMIELC_00082 220668.lp_0148 4.9e-151 540.4 Lactobacillaceae cbiQ ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 iSB619.SA_RS14165 Bacteria 1TPMV@1239,3F3Y9@33958,4HBTW@91061,COG0619@1,COG0619@2 NA|NA|NA P cobalt transport PGHMIELC_00083 220668.lp_0149 0.0 1094.7 Lactobacillaceae ykoD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 ko:K02006,ko:K16786,ko:K16787 ko02010,map02010 M00245,M00246,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPH8@1239,3F4XP@33958,4HAJM@91061,COG1122@1,COG1122@2 NA|NA|NA P ABC transporter, ATP-binding protein PGHMIELC_00084 220668.lp_0150 2.5e-98 364.8 Lactobacillaceae ko:K16924,ko:K16927 M00582 ko00000,ko00002,ko02000 3.A.1.29,3.A.1.32 Bacteria 1V1GT@1239,3F5A7@33958,4HGAE@91061,COG4720@1,COG4720@2 NA|NA|NA S UPF0397 protein PGHMIELC_00085 220668.lp_0152 1.6e-129 468.8 Lactobacillaceae ko:K03486,ko:K03492,ko:K03710 ko00000,ko03000 Bacteria 1TTCD@1239,3F4DA@33958,4HEXQ@91061,COG2188@1,COG2188@2 NA|NA|NA K UbiC transcription regulator-associated domain protein PGHMIELC_00086 220668.lp_0154 8.3e-54 216.1 Lactobacillaceae Bacteria 1U5XD@1239,3F6N7@33958,4IFKR@91061,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family PGHMIELC_00087 220668.lp_0155 4.6e-143 513.8 Lactobacillaceae Bacteria 1U5AQ@1239,2CBBX@1,309KV@2,3F6UY@33958,4IF25@91061 NA|NA|NA PGHMIELC_00088 220668.lp_0156 7.6e-149 533.1 Lactobacillaceae Bacteria 1U5AP@1239,2CBBX@1,309KU@2,3F5EA@33958,4IF24@91061 NA|NA|NA PGHMIELC_00089 220668.lp_0158 9.1e-89 332.8 Lactobacillaceae Bacteria 1VFYC@1239,2DPIQ@1,3328X@2,3F7RW@33958,4HNHQ@91061 NA|NA|NA PGHMIELC_00090 220668.lp_0159 5.5e-144 516.9 Lactobacillaceae Bacteria 1TPZN@1239,3F4V8@33958,4HBJ8@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Oxidoreductase, short chain dehydrogenase reductase family protein PGHMIELC_00091 220668.lp_0160 2.3e-170 604.7 Lactobacillaceae yjjC ko:K01990,ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQHS@1239,3F4JT@33958,4HC34@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter PGHMIELC_00092 220668.lp_0161 7.2e-300 1035.8 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPIG@1239,3F4PV@33958,4H9SK@91061,COG3559@1,COG3559@2 NA|NA|NA M Exporter of polyketide antibiotics PGHMIELC_00093 220668.lp_0162 1.6e-117 428.7 Lactobacillaceae ko:K09017 ko00000,ko03000 Bacteria 1VG1F@1239,3F6KD@33958,4HPER@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator PGHMIELC_00094 220668.lp_0163 2.1e-277 961.1 Lactobacillaceae ko:K03522 ko00000,ko04147 Bacteria 1TPC8@1239,3F4ZT@33958,4HAE2@91061,COG1960@1,COG1960@2,COG2025@1,COG2025@2 NA|NA|NA C Electron transfer flavoprotein FAD-binding domain PGHMIELC_00095 220668.lp_0164 8.6e-74 283.1 Lactobacillaceae folT 2.7.13.3 ko:K02478,ko:K07704 ko02020,map02020 M00492 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TTD8@1239,3F650@33958,4IFBB@91061,COG3275@1,COG3275@2 NA|NA|NA T ECF transporter, substrate-specific component PGHMIELC_00097 220668.lp_0165 1.1e-92 345.9 Lactobacillaceae Bacteria 1V5RP@1239,3F6G7@33958,4HP5H@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family PGHMIELC_00098 220668.lp_0166 2.2e-190 671.4 Lactobacillaceae dhaK GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019637,GO:0019751,GO:0033554,GO:0034308,GO:0042180,GO:0042182,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0047324,GO:0050896,GO:0051716,GO:0061610,GO:0071704,GO:1901135,GO:1901575,GO:1901615 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 ko:K00863,ko:K05878,ko:K05879 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 M00344 R01011,R01012,R01059 RC00002,RC00015,RC00017 ko00000,ko00001,ko00002,ko01000 iEcHS_1320.EcHS_A1304,iUMNK88_1353.UMNK88_1515,iYL1228.KPN_03495 Bacteria 1UZIM@1239,3F4HN@33958,4HEWJ@91061,COG2376@1,COG2376@2 NA|NA|NA G Dak1 domain PGHMIELC_00099 220668.lp_0168 5e-187 660.2 Lactobacillaceae dhaK GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019637,GO:0019751,GO:0033554,GO:0034308,GO:0042180,GO:0042182,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0047324,GO:0050896,GO:0051716,GO:0061610,GO:0071704,GO:1901135,GO:1901575,GO:1901615 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 ko:K00863,ko:K05878,ko:K05879 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 M00344 R01011,R01012,R01059 RC00002,RC00015,RC00017 ko00000,ko00001,ko00002,ko01000 iEcHS_1320.EcHS_A1304,iUMNK88_1353.UMNK88_1515,iYL1228.KPN_03495 Bacteria 1TP92@1239,3F4F2@33958,4H9VS@91061,COG2376@1,COG2376@2 NA|NA|NA G Dak1 domain PGHMIELC_00100 220668.lp_0169 1.9e-101 375.2 Lactobacillaceae dhaL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0046872,GO:0047324,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.1.121 ko:K05879 ko00561,ko01100,map00561,map01100 R01012 RC00015,RC00017 ko00000,ko00001,ko01000 Bacteria 1V4FH@1239,3F5VS@33958,4HGZY@91061,COG1461@1,COG1461@2 NA|NA|NA S Dak2 PGHMIELC_00101 220668.lp_0170 9e-57 226.1 Lactobacillaceae dhaM GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324 2.7.1.121 ko:K05881 ko00561,map00561 R01012 RC00015,RC00017 ko00000,ko00001,ko01000,ko02000 Bacteria 1VF32@1239,3F6YE@33958,4HKCN@91061,COG3412@1,COG3412@2 NA|NA|NA S PTS system fructose IIA component PGHMIELC_00102 220668.lp_0171 8.6e-133 479.6 Lactobacillaceae glpF ko:K02440,ko:K06188 ko00000,ko02000 1.A.8,1.A.8.1,1.A.8.2 Bacteria 1TP4T@1239,3F4J6@33958,4HAWP@91061,COG0580@1,COG0580@2 NA|NA|NA U Belongs to the MIP aquaporin (TC 1.A.8) family PGHMIELC_00103 220668.lp_0172 1e-190 672.5 Lactobacillaceae malR ko:K02529 ko00000,ko03000 Bacteria 1TPZM@1239,3F4TM@33958,4H9ZT@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family PGHMIELC_00104 220668.lp_0173 2e-180 638.3 Lactobacillaceae yvdE ko:K02529 ko00000,ko03000 Bacteria 1U6Z4@1239,3F3ZC@33958,4HC2A@91061,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor PGHMIELC_00105 220668.lp_0174 0.0 1169.5 Lactobacillaceae malL 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13,GH31 Bacteria 1UY2T@1239,3FC10@33958,4HBRE@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain PGHMIELC_00106 220668.lp_0175 2.1e-230 804.7 Lactobacillaceae mdxE ko:K15770 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 iYO844.BSU34610 Bacteria 1TPU9@1239,3FC77@33958,4HBHE@91061,COG2182@1,COG2182@2 NA|NA|NA G Bacterial extracellular solute-binding protein PGHMIELC_00107 220668.lp_0176 1.9e-226 791.6 Lactobacillaceae malC GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0042623,GO:0042626,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351 ko:K02025,ko:K02026,ko:K05814,ko:K15771 ko02010,map02010 M00198,M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.3 Bacteria 1TR2A@1239,3F4J1@33958,4HB8H@91061,COG1175@1,COG1175@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component PGHMIELC_00108 220668.lp_0177 1.4e-161 575.5 Lactobacillaceae malD GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0015774,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0033037,GO:0034219,GO:0042623,GO:0042626,GO:0042956,GO:0043211,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 ko:K15772 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 Bacteria 1TRB7@1239,3F4NP@33958,4HC5K@91061,COG3833@1,COG3833@2 NA|NA|NA P ABC transporter permease PGHMIELC_00109 220668.lp_0178 1.8e-150 538.5 Lactobacillaceae malA Bacteria 1V7S4@1239,3F4T5@33958,4HJ3V@91061,COG5521@1,COG5521@2 NA|NA|NA S maltodextrose utilization protein MalA PGHMIELC_00110 220668.lp_0179 9.1e-261 905.6 Lactobacillaceae malS 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 R02108,R02112,R11262 ko00000,ko00001,ko01000 GH13 Bacteria 1U7JS@1239,3F5JM@33958,4HF0J@91061,COG0366@1,COG0366@2 NA|NA|NA G Glycogen debranching enzyme, glucanotransferase domain PGHMIELC_00111 220668.lp_0180 4e-209 733.8 Lactobacillaceae msmK ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko02000 3.A.1.1 Bacteria 1TP2M@1239,3FC3D@33958,4HAMQ@91061,COG3842@1,COG3842@2 NA|NA|NA P Belongs to the ABC transporter superfamily PGHMIELC_00112 220668.lp_0181 0.0 1562.7 Lactobacillaceae mapA 2.4.1.8 ko:K00691 ko00500,ko01100,map00500,map01100 R01555 RC00049 ko00000,ko00001,ko01000 GH65 Bacteria 1TQMB@1239,3F3PG@33958,4HAVB@91061,COG1554@1,COG1554@2 NA|NA|NA G hydrolase, family 65, central catalytic PGHMIELC_00113 220668.lp_0182 0.0 1882.1 Lactobacillaceae 3.2.1.96 ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Bacteria 1TPGB@1239,3F77D@33958,4HDJJ@91061,COG3291@1,COG3291@2,COG4724@1,COG4724@2 NA|NA|NA G Glycosyl hydrolase family 85 PGHMIELC_00114 60520.HR47_06360 1.5e-45 188.3 Lactobacillaceae ygbF ko:K15383 ko00000,ko02000 9.A.58.2 Bacteria 1VBI9@1239,3F7IR@33958,4HMY5@91061,COG4095@1,COG4095@2 NA|NA|NA S Sugar efflux transporter for intercellular exchange PGHMIELC_00115 220668.lp_0184 5.4e-169 600.1 Lactobacillaceae scrK 2.7.1.2,2.7.1.4 ko:K00845,ko:K00847 ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R00760,R00867,R01600,R01786,R03920 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQU4@1239,3F3K8@33958,4HA1C@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family PGHMIELC_00116 220668.lp_0185 0.0 1161.4 Lactobacillaceae scrA 2.7.1.193,2.7.1.211,5.3.1.1 ko:K01803,ko:K02755,ko:K02756,ko:K02757,ko:K02802,ko:K02803,ko:K02804,ko:K02808,ko:K02809,ko:K02810 ko00010,ko00051,ko00500,ko00520,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko02060,map00010,map00051,map00500,map00520,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map02060 M00001,M00002,M00003,M00267,M00269,M00271 R00811,R01015,R05199 RC00017,RC00423,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko04147 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system PGHMIELC_00117 220668.lp_0187 1.4e-305 1054.7 Lactobacillaceae scrB 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 GH32 Bacteria 1TPAE@1239,3F4UD@33958,4H9Y7@91061,COG1621@1,COG1621@2 NA|NA|NA G invertase PGHMIELC_00118 220668.lp_0188 9.1e-173 612.8 Lactobacillaceae scrR ko:K02529,ko:K03484 ko00000,ko03000 Bacteria 1TQ7K@1239,3F4JE@33958,4H9V1@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family PGHMIELC_00119 220668.lp_0189 0.0 1189.1 Lactobacillaceae 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13,GH31 Bacteria 1TP53@1239,3F41I@33958,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain protein PGHMIELC_00120 220668.lp_0190 1.1e-65 255.8 Lactobacillaceae 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 R00944 RC00026,RC00111 ko00000,ko00001,ko01000 Bacteria 1TQ0M@1239,3F3WU@33958,4HA8M@91061,COG0604@1,COG0604@2 NA|NA|NA C nadph quinone reductase PGHMIELC_00121 220668.lp_0190 4e-81 307.4 Lactobacillaceae 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 R00944 RC00026,RC00111 ko00000,ko00001,ko01000 Bacteria 1TQ0M@1239,3F3WU@33958,4HA8M@91061,COG0604@1,COG0604@2 NA|NA|NA C nadph quinone reductase PGHMIELC_00122 220668.lp_0192 1.1e-217 762.7 Lactobacillaceae nhaC ko:K03315 ko00000,ko02000 2.A.35 Bacteria 1TQ3B@1239,3F3VX@33958,4HA18@91061,COG1757@1,COG1757@2 NA|NA|NA C Na H antiporter NhaC PGHMIELC_00123 220668.lp_0193 0.0 1176.4 Lactobacillaceae 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13,GH31 Bacteria 1TP53@1239,3F41I@33958,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain protein PGHMIELC_00124 220668.lp_0194 5e-165 587.0 Lactobacillaceae mleR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 Bacteria 1V5VW@1239,3F5F3@33958,4HHDY@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain PGHMIELC_00125 220668.lp_0197 0.0 1214.9 Lactobacillaceae 3.6.4.13 ko:K03496,ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036,ko04812 Bacteria 1TQBI@1239,3F4FM@33958,4HBAT@91061,COG3827@1,COG3827@2,COG4932@1,COG4932@2 NA|NA|NA M domain protein PGHMIELC_00127 220668.lp_0199 2.1e-157 561.6 Lactobacillaceae hipB GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K15773 ko00000,ko02048,ko03000 Bacteria 1VDMN@1239,3F5A3@33958,4HDVP@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix PGHMIELC_00128 220668.lp_0200 0.0 1090.9 Lactobacillaceae oppA ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F3JE@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substratebinding protein PGHMIELC_00129 220668.lp_0201 8.6e-309 1065.4 Lactobacillaceae oppA ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F3JE@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substratebinding protein PGHMIELC_00130 220668.lp_0202 4.5e-79 300.4 Lactobacillaceae yiaC ko:K03826 ko00000,ko01000 Bacteria 1VAFS@1239,3F7FI@33958,4HIRW@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain PGHMIELC_00131 220668.lp_0203 8.8e-215 752.7 Lactobacillaceae serA 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1V410@1239,3F4JJ@33958,4H9PH@91061,COG0111@1,COG0111@2 NA|NA|NA EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family PGHMIELC_00132 220668.lp_0204 7e-203 713.0 Lactobacillaceae serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP6Y@1239,3F4IU@33958,4HATT@91061,COG1932@1,COG1932@2 NA|NA|NA E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine PGHMIELC_00133 220668.lp_0205 6.7e-113 413.3 Lactobacillaceae pgm1 Bacteria 1V6ES@1239,3F5SD@33958,4HGZI@91061,COG0406@1,COG0406@2 NA|NA|NA G phosphoglycerate mutase PGHMIELC_00134 60520.HR47_03225 2.9e-179 634.4 Lactobacillaceae yghZ ko:K19265 ko00000,ko01000 Bacteria 1TRS0@1239,3F414@33958,4HAZ2@91061,COG0667@1,COG0667@2 NA|NA|NA C Aldo keto reductase family protein PGHMIELC_00135 220668.lp_0207 4.9e-34 149.8 Lactobacillaceae Bacteria 1U69W@1239,29P8V@1,30A6Z@2,3F7EF@33958,4IG13@91061 NA|NA|NA PGHMIELC_00136 220668.lp_0208 4.8e-60 236.9 Lactobacillaceae ko:K05937 ko00000 Bacteria 1V6QB@1239,3F88X@33958,4HINV@91061,COG5646@1,COG5646@2 NA|NA|NA S Domain of unknown function (DU1801) PGHMIELC_00137 220668.lp_0209 3.8e-162 577.4 Lactobacillaceae FbpA ko:K12341 ko03070,map03070 ko00000,ko00001,ko02044 1.B.40.1.1 Bacteria 1TQ8A@1239,3F4QZ@33958,4H9UF@91061,COG1293@1,COG1293@2 NA|NA|NA K Domain of unknown function (DUF814) PGHMIELC_00138 220668.lp_0210 1e-218 765.8 Lactobacillaceae ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0409 Bacteria 1TQ22@1239,3F48Z@33958,4HA7K@91061,COG0282@1,COG0282@2 NA|NA|NA F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction PGHMIELC_00140 220668.lp_0213 3.5e-58 230.7 Lactobacillaceae crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 1VM30@1239,3F8A8@33958,4HRC4@91061,COG0239@1,COG0239@2 NA|NA|NA U Important for reducing fluoride concentration in the cell, thus reducing its toxicity PGHMIELC_00141 220668.lp_0214 8.5e-50 203.0 Bacteria crcB ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria COG0239@1,COG0239@2 NA|NA|NA D Important for reducing fluoride concentration in the cell, thus reducing its toxicity PGHMIELC_00142 220668.lp_0215 9.5e-262 909.1 Lactobacillaceae ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 3.A.1.121.1,3.A.1.121.3 Bacteria 1TQNA@1239,3F4UR@33958,4H9VW@91061,COG0488@1,COG0488@2 NA|NA|NA S ATPases associated with a variety of cellular activities PGHMIELC_00143 220668.lp_0217 2e-115 421.8 Lactobacillaceae ko:K16785 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TUDZ@1239,3F4FG@33958,4HCPC@91061,COG0619@1,COG0619@2 NA|NA|NA P cobalt transport PGHMIELC_00144 220668.lp_0218 1.4e-259 901.7 Lactobacillaceae ko:K02006,ko:K16784,ko:K16786,ko:K16787,ko:K16927 ko02010,map02010 M00245,M00246,M00581,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPH8@1239,3FBS0@33958,4HAJM@91061,COG1122@1,COG1122@2 NA|NA|NA P ABC transporter PGHMIELC_00145 220668.lp_0219 3.1e-101 374.4 Lactobacillaceae ko:K16925 M00582 ko00000,ko00002,ko02000 3.A.1.30 Bacteria 1V5J6@1239,3FBNX@33958,4HGBR@91061,COG4721@1,COG4721@2 NA|NA|NA S ABC transporter permease PGHMIELC_00146 220668.lp_0220 4.8e-90 337.0 Lactobacillaceae btuE 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 Bacteria 1V3M3@1239,3F6A9@33958,4HH5Q@91061,COG0386@1,COG0386@2 NA|NA|NA O Belongs to the glutathione peroxidase family PGHMIELC_00147 220668.lp_0221 1.4e-158 565.5 Lactobacillaceae dkgB Bacteria 1TPM1@1239,3F4XF@33958,4HACK@91061,COG0656@1,COG0656@2 NA|NA|NA S reductase PGHMIELC_00148 220668.lp_0223 1.4e-78 298.9 Lactobacillaceae greA ko:K03624,ko:K04760 ko00000,ko03021 Bacteria 1V1G3@1239,3F6ZK@33958,4HW8H@91061,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides PGHMIELC_00149 220668.lp_0224 1e-69 269.2 Lactobacillaceae Bacteria 1U60Z@1239,29P27@1,30A0D@2,3F6T6@33958,4IFPT@91061 NA|NA|NA PGHMIELC_00150 220668.lp_0226 7.4e-132 476.5 Lactobacillaceae nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0008150,GO:0008152,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135 3.1.1.31,3.5.99.6 ko:K01057,ko:K02564 ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R00765,R02035 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP10@1239,3F3NR@33958,4HAG4@91061,COG0363@1,COG0363@2 NA|NA|NA G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion PGHMIELC_00152 220668.lp_0228 3.9e-278 963.4 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase PGHMIELC_00153 220668.lp_0230 0.0 1146.3 Lactobacillaceae mtlA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.197 ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 Bacteria 1TPE3@1239,3F52S@33958,4HAVV@91061,COG2213@1,COG2213@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit PGHMIELC_00154 220668.lp_0231 0.0 1333.9 Lactobacillaceae mtlR ko:K03483 ko00000,ko03000 Bacteria 1TQT1@1239,3F561@33958,4HABH@91061,COG3711@1,COG3711@2 NA|NA|NA K Mga helix-turn-helix domain PGHMIELC_00155 220668.lp_0232 1.7e-78 298.5 Lactobacillaceae mtlF 2.7.1.197 ko:K02798,ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 Bacteria 1V77P@1239,3F6EP@33958,4HIM2@91061,COG4668@1,COG4668@2 NA|NA|NA G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane PGHMIELC_00156 220668.lp_0233 4.3e-222 776.9 Lactobacillaceae mtlD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006059,GO:0006066,GO:0008150,GO:0008152,GO:0008926,GO:0009056,GO:0009987,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019400,GO:0019405,GO:0019407,GO:0019592,GO:0019594,GO:0019751,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:1901575,GO:1901615,GO:1901616 1.1.1.17 ko:K00009 ko00051,map00051 R02703 RC00085 ko00000,ko00001,ko01000 iSBO_1134.SBO_3598,iSbBS512_1146.SbBS512_E4017 Bacteria 1TPZU@1239,3F448@33958,4H9S3@91061,COG0246@1,COG0246@2 NA|NA|NA C mannitol-1-phosphate 5-dehydrogenase activity PGHMIELC_00157 220668.lp_0235 2.1e-73 282.0 Lactobacillaceae Bacteria 1U5NP@1239,29NVD@1,309TG@2,3F686@33958,4IFD9@91061 NA|NA|NA PGHMIELC_00158 220668.lp_0236 1.4e-56 225.3 Lactobacillaceae trxA1 ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1VA3Y@1239,3F7I4@33958,4HKKX@91061,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family PGHMIELC_00159 220668.lp_0237 1.1e-50 205.7 Lactobacillaceae Bacteria 1U6QA@1239,29PK3@1,30AI8@2,3F8AK@33958,4IGHE@91061 NA|NA|NA PGHMIELC_00160 220668.lp_0239 6.6e-96 356.7 Lactobacillaceae Bacteria 1U660@1239,29P5Z@1,30A44@2,3F75C@33958,4IFW1@91061 NA|NA|NA PGHMIELC_00161 220668.lp_0240 2e-62 245.0 Lactobacillaceae Bacteria 1U5WU@1239,2C2FZ@1,309XY@2,3F6MP@33958,4IFKC@91061 NA|NA|NA PGHMIELC_00162 220668.lp_0242 5e-81 307.0 Lactobacillaceae ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 Bacteria 1V44G@1239,3F68C@33958,4HH8C@91061,COG0105@1,COG0105@2 NA|NA|NA F Belongs to the NDK family PGHMIELC_00163 220668.lp_0243 7.6e-255 885.9 Lactobacillaceae Bacteria 1UCBA@1239,3F3JA@33958,4HBCI@91061,COG4320@1,COG4320@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2252) PGHMIELC_00164 220668.lp_0244 5.4e-98 363.6 Lactobacillaceae yieF ko:K19784 ko00000 Bacteria 1V2V7@1239,3FCC1@33958,4HFMV@91061,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase PGHMIELC_00165 220668.lp_0245 3.6e-123 447.6 Lactobacillaceae Bacteria 1V1UW@1239,3FBEG@33958,4IPXK@91061,COG2188@1,COG2188@2 NA|NA|NA K helix_turn_helix gluconate operon transcriptional repressor PGHMIELC_00166 220668.lp_0247 5.1e-229 800.0 Lactobacillaceae pts3C ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 Bacteria 1TP8D@1239,3F54Z@33958,4H9W2@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane PGHMIELC_00167 220668.lp_0248 4.7e-39 166.8 Lactobacillaceae Bacteria 1U77X@1239,29PYN@1,30AX4@2,3F937@33958,4IH2Q@91061 NA|NA|NA PGHMIELC_00168 220668.lp_0249 8.5e-212 742.7 Lactobacillaceae ko:K09963 ko00000 Bacteria 1TRIY@1239,3F4FK@33958,4H9V2@91061,COG3589@1,COG3589@2 NA|NA|NA S Bacterial protein of unknown function (DUF871) PGHMIELC_00169 220668.lp_0250 2.3e-212 744.6 Lactobacillaceae dho 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPXM@1239,3F4S7@33958,4HBNV@91061,COG3964@1,COG3964@2 NA|NA|NA S Amidohydrolase family PGHMIELC_00170 220668.lp_0251 8e-202 709.5 Lactobacillaceae selA 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 R08219 RC01246 ko00000,ko00001,ko01000 Bacteria 1TQT8@1239,3F4MN@33958,4HC3U@91061,COG1921@1,COG1921@2 NA|NA|NA H L-seryl-tRNA selenium transferase PGHMIELC_00171 220668.lp_0252 4.6e-129 467.2 Lactobacillaceae 4.1.2.14 ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 M00061,M00631 R05605 RC00307,RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQX7@1239,2DBAP@1,2Z844@2,3F5QS@33958,4HABQ@91061 NA|NA|NA S KDGP aldolase PGHMIELC_00172 220668.lp_0253 4.5e-191 673.7 Lactobacillaceae kdgK 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQER@1239,3FC1M@33958,4HEEF@91061,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase PGHMIELC_00173 220668.lp_0254 5.5e-95 353.6 Lactobacillaceae cysE 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR42@1239,3F63E@33958,4HAKS@91061,COG1045@1,COG1045@2 NA|NA|NA E Bacterial transferase hexapeptide (six repeats) PGHMIELC_00174 220668.lp_0255 9.8e-211 739.2 Lactobacillaceae metC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.5.1.48,4.4.1.1,4.4.1.2,4.4.1.8 ko:K01739,ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00782,R00999,R01001,R01283,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC7@1239,3F3Y2@33958,4HAFQ@91061,COG0626@1,COG0626@2 NA|NA|NA E cystathionine PGHMIELC_00175 220668.lp_0256 4.5e-166 590.5 Lactobacillaceae mccA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042127,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0065007,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.134,2.5.1.47 ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00609 R00897,R03601,R04859,R10305 RC00020,RC00069,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS02385 Bacteria 1TP30@1239,3F4VD@33958,4HAMU@91061,COG0031@1,COG0031@2 NA|NA|NA E Belongs to the cysteine synthase cystathionine beta- synthase family PGHMIELC_00176 220668.lp_0257 7.8e-159 566.2 Lactobacillaceae map GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 1TQC1@1239,3F3MK@33958,4H9S9@91061,COG0024@1,COG0024@2 NA|NA|NA E Methionine Aminopeptidase PGHMIELC_00177 220668.lp_0259 4.3e-141 507.3 Lactobacillaceae pnuC ko:K03811 ko00000,ko02000 4.B.1.1 Bacteria 1VE5T@1239,3F3MB@33958,4HMNW@91061,COG3201@1,COG3201@2 NA|NA|NA H nicotinamide mononucleotide transporter PGHMIELC_00178 220668.lp_0260 7.3e-43 179.5 Lactobacillaceae Bacteria 1VGSH@1239,3F84H@33958,4HQ68@91061,COG3877@1,COG3877@2 NA|NA|NA S Protein of unknown function (DUF2089) PGHMIELC_00179 220668.lp_0261 1.7e-42 178.3 Lactobacillaceae Bacteria 1VYT7@1239,2FGRX@1,348MC@2,3F8YI@33958,4HY30@91061 NA|NA|NA PGHMIELC_00180 220668.lp_0262 3.5e-129 467.6 Lactobacillaceae treR ko:K03486,ko:K03492,ko:K03710 ko00000,ko03000 Bacteria 1TRF6@1239,3F62J@33958,4HDCX@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA PGHMIELC_00181 220668.lp_0263 0.0 1139.8 Lactobacillaceae treC GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005991,GO:0005993,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008788,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0015927,GO:0016052,GO:0016787,GO:0016798,GO:0033554,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046352,GO:0050896,GO:0051716,GO:0071704,GO:1901575 3.2.1.93 ko:K01226 ko00500,map00500 R00837,R06113 RC00049 ko00000,ko00001,ko01000 GH13 iECW_1372.ECW_m4600,iEKO11_1354.EKO11_4072,iEcE24377_1341.EcE24377A_4811,iEcSMS35_1347.EcSMS35_4720,iWFL_1372.ECW_m4600 Bacteria 1TP53@1239,3F41I@33958,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain protein PGHMIELC_00182 220668.lp_0264 0.0 1261.1 Lactobacillaceae treB 2.7.1.193,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K02808,ko:K02809,ko:K02810 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00267,M00268,M00269,M00270,M00271,M00272,M00303,M00806 R00811,R02738,R02780,R04111,R04394,R05132,R05199,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system PGHMIELC_00183 220668.lp_0265 0.0 1194.1 Lactobacillaceae pts4ABC 2.7.1.193,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K02808,ko:K02809,ko:K02810 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00267,M00268,M00269,M00270,M00271,M00272,M00303,M00806 R00811,R02738,R02780,R04111,R04394,R05132,R05199,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TP5X@1239,3F5R5@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system, EIIB PGHMIELC_00184 220668.lp_0266 1.4e-144 518.8 Lactobacillaceae Bacteria 1VW0F@1239,2F4SR@1,33XFD@2,3F6TR@33958,4HWCG@91061 NA|NA|NA PGHMIELC_00185 220668.lp_0271 6.3e-100 370.2 Lactobacillaceae ubiX GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3JV@1239,3F5PD@33958,4HFZX@91061,COG0163@1,COG0163@2 NA|NA|NA H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN PGHMIELC_00186 220668.lp_0272 4.6e-70 270.4 Lactobacillaceae Bacteria 1VX0V@1239,2F603@1,33YIJ@2,3F6YU@33958,4HXF9@91061 NA|NA|NA PGHMIELC_00187 220668.lp_0273 1.8e-72 278.5 Lactobacillaceae Bacteria 1V6FK@1239,3F73Q@33958,4HKZD@91061,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator PGHMIELC_00188 220668.lp_0274 4.3e-121 440.7 Lactobacillaceae Bacteria 1V3R8@1239,3F5TD@33958,4I42T@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family PGHMIELC_00189 220668.lp_0275 6.5e-233 813.1 Lactobacillaceae mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 1TPT1@1239,3F49Y@33958,4HAEA@91061,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system PGHMIELC_00190 220668.lp_0276 1.5e-115 422.2 Lactobacillaceae Bacteria 1UG55@1239,29V56@1,30GIU@2,3F5HR@33958,4IF3C@91061 NA|NA|NA PGHMIELC_00191 220668.lp_0277 1.7e-40 171.8 Lactobacillaceae Bacteria 1U6GU@1239,29PEH@1,30ACP@2,3F7W4@33958,4IG90@91061 NA|NA|NA PGHMIELC_00192 220668.lp_0279 1e-40 172.2 Lactobacillaceae Bacteria 1U66B@1239,2900D@1,30A4B@2,3F767@33958,4IFWH@91061 NA|NA|NA PGHMIELC_00193 220668.lp_0280 9.7e-253 879.0 Lactobacillaceae ydiC1 Bacteria 1TPRN@1239,3F4D4@33958,4HBXJ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_00194 220668.lp_0281 3.3e-65 254.2 Lactobacillaceae Bacteria 1U6QY@1239,3F8C1@33958,4IGI8@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance PGHMIELC_00195 220668.lp_0282 2.2e-249 867.8 Lactobacillaceae Bacteria 1VU2I@1239,3F475@33958,4HHZT@91061,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor PGHMIELC_00196 220668.lp_0283 4.4e-129 467.2 Lactobacillaceae Bacteria 1TS81@1239,3F3JF@33958,4H9NE@91061,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C terminal PGHMIELC_00197 220668.lp_0284 9.2e-49 199.1 Lactobacillaceae Bacteria 1U64G@1239,29P4U@1,30A31@2,3F70P@33958,4IFU0@91061 NA|NA|NA PGHMIELC_00198 220668.lp_0285 2.1e-129 468.4 Lactobacillaceae yidA Bacteria 1TS9A@1239,3F6D3@33958,4HCBF@91061,COG1737@1,COG1737@2 NA|NA|NA K Helix-turn-helix domain, rpiR family PGHMIELC_00199 220668.lp_0286 3e-243 847.4 Lactobacillaceae celB ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 iYO844.BSU38390 Bacteria 1TP8D@1239,3F3Q4@33958,4H9W2@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane PGHMIELC_00200 220668.lp_0287 9.9e-57 225.7 Lactobacillaceae Bacteria 1U699@1239,29P89@1,30A6C@2,3F7CE@33958,4IG0E@91061 NA|NA|NA PGHMIELC_00201 220668.lp_0289 2.1e-41 174.5 Lactobacillaceae Bacteria 1U6HR@1239,29PF7@1,30ADC@2,3F7Y0@33958,4IGA2@91061 NA|NA|NA PGHMIELC_00202 220668.lp_0290 1.4e-184 652.1 Lactobacillaceae brpA Bacteria 1TR1B@1239,3F3MQ@33958,4HA09@91061,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-like function transcriptional attenuator common domain protein PGHMIELC_00203 220668.lp_0291 2.2e-257 894.4 Lactobacillaceae loxD 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 R00475 RC00042 ko00000,ko00001,ko01000 Bacteria 1TPBC@1239,3F4AD@33958,4H9UU@91061,COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidases, C-terminal domain PGHMIELC_00204 220668.lp_0292 1.3e-47 195.3 Lactobacillaceae Bacteria 1U66J@1239,29P6D@1,30A4H@2,3F76U@33958,4IFWU@91061 NA|NA|NA PGHMIELC_00205 220668.lp_0293 2.7e-123 448.0 Lactobacillaceae 2.7.6.5 ko:K00951,ko:K07816 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 1TSC9@1239,3FBJN@33958,4HBE0@91061,COG2357@1,COG2357@2 NA|NA|NA S RelA SpoT domain protein PGHMIELC_00206 220668.lp_0294 3.1e-104 384.4 Lactobacillaceae Bacteria 1VI1M@1239,3F530@33958,4HPZV@91061,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator PGHMIELC_00207 60520.HR47_03545 0.0 1380.9 Lactobacillaceae ydgH GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006790,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0030312,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046505,GO:0046506,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901576 ko:K06994,ko:K07003 ko00000 Bacteria 1TQ7C@1239,3FCCY@33958,4HBM6@91061,COG1511@1,COG1511@2,COG2409@1,COG2409@2 NA|NA|NA S MMPL family PGHMIELC_00208 220668.lp_0296 1e-107 396.0 Lactobacillaceae tag 3.2.2.20 ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1UYWG@1239,3F5KA@33958,4HGWW@91061,COG2818@1,COG2818@2 NA|NA|NA L glycosylase PGHMIELC_00209 220668.lp_0297 0.0 1244.6 Lactobacillaceae XK27_00720 ko:K13730 ko05100,map05100 ko00000,ko00001 Bacteria 1U5IM@1239,3F61G@33958,4IF9E@91061,COG4886@1,COG4886@2 NA|NA|NA S Leucine-rich repeat (LRR) protein PGHMIELC_00210 220668.lp_0297 2.3e-26 124.0 Lactobacillaceae XK27_00720 ko:K13730 ko05100,map05100 ko00000,ko00001 Bacteria 1U5IM@1239,3F61G@33958,4IF9E@91061,COG4886@1,COG4886@2 NA|NA|NA S Leucine-rich repeat (LRR) protein PGHMIELC_00211 220668.lp_0298 1e-188 666.4 Lactobacillaceae yclI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPSE@1239,3FC8Y@33958,4HDMR@91061,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain PGHMIELC_00212 220668.lp_0299 7.1e-121 439.9 Lactobacillaceae yclH ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TP5M@1239,3F57B@33958,4HBJW@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter PGHMIELC_00213 220668.lp_0300 2.5e-114 418.3 Bacteria ko:K07052 ko00000 Bacteria COG1266@1,COG1266@2 NA|NA|NA V CAAX protease self-immunity PGHMIELC_00214 220668.lp_0301 1.2e-53 215.7 Lactobacillaceae ko:K07052 ko00000 Bacteria 1U62B@1239,3F6V5@33958,4IFRB@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity PGHMIELC_00215 220668.lp_0301 3.4e-25 120.2 Lactobacillaceae ko:K07052 ko00000 Bacteria 1U62B@1239,3F6V5@33958,4IFRB@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity PGHMIELC_00216 220668.lp_0827 3.3e-52 210.7 Lactobacillaceae Bacteria 1VX4A@1239,2C26E@1,3424N@2,3F70Q@33958,4HXT9@91061 NA|NA|NA PGHMIELC_00217 220668.lp_0828 3e-72 277.7 Lactobacillaceae Bacteria 1U62H@1239,29P38@1,30A1E@2,3F6VJ@33958,4IFRM@91061 NA|NA|NA PGHMIELC_00218 220668.lp_0829 6.6e-131 473.4 Lactobacillaceae 1.5.1.39 ko:K19286 ko00740,ko01100,map00740,map01100 R05705,R05706 RC00126 ko00000,ko00001,ko01000 Bacteria 1UB8S@1239,3F4IY@33958,4HEGP@91061,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase PGHMIELC_00219 1136177.KCA1_0666 4e-154 551.2 Firmicutes Bacteria 1UJB6@1239,COG2211@1,COG2211@2 NA|NA|NA G Transmembrane secretion effector PGHMIELC_00220 220668.lp_0834 2.8e-298 1030.4 Lactobacillaceae glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPX3@1239,3F3WI@33958,4H9ZF@91061,COG0554@1,COG0554@2 NA|NA|NA F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate PGHMIELC_00221 220668.lp_0835 8.6e-142 509.6 Lactobacillaceae Bacteria 1W4RS@1239,2CBBX@1,309KW@2,3F61U@33958,4IF26@91061 NA|NA|NA PGHMIELC_00223 220668.lp_0836 1.9e-71 275.0 Lactobacillaceae spxA 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1V3QC@1239,3F6DX@33958,4IFFY@91061,COG1393@1,COG1393@2 NA|NA|NA P ArsC family PGHMIELC_00224 220668.lp_0837 1.5e-33 148.3 Lactobacillaceae Bacteria 1U6JS@1239,29PGP@1,30AEU@2,3F81T@33958,4IGC9@91061 NA|NA|NA PGHMIELC_00225 220668.lp_0838 1.1e-89 335.9 Lactobacillaceae Bacteria 1VKIA@1239,3F86G@33958,4HNUJ@91061,COG4767@1,COG4767@2 NA|NA|NA V VanZ like family PGHMIELC_00226 220668.lp_0840 3.1e-174 617.8 Lactobacillaceae ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1UYQB@1239,3F3NG@33958,4HE3Y@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_00227 220668.lp_0840 1.4e-28 131.7 Lactobacillaceae ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1UYQB@1239,3F3NG@33958,4HE3Y@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_00228 220668.lp_0841 3.2e-175 620.9 Lactobacillaceae ppx 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 1TS3I@1239,3F3SR@33958,4HAQS@91061,COG0248@1,COG0248@2 NA|NA|NA FP exopolyphosphatase PGHMIELC_00229 220668.lp_0842 0.0 1429.5 Lactobacillaceae ppk GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 iJN746.PP_5217 Bacteria 1TNZM@1239,3F3PE@33958,4HA88@91061,COG0855@1,COG0855@2 NA|NA|NA P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) PGHMIELC_00230 220668.lp_0843 1.8e-289 1001.1 Lactobacillaceae ppx3 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 1VT8Q@1239,3F49N@33958,4HB84@91061,COG0248@1,COG0248@2 NA|NA|NA FP exopolyphosphatase PGHMIELC_00231 220668.lp_0844 5e-153 547.0 Lactobacillaceae licD ko:K07271 ko00000,ko01000 Bacteria 1VBSV@1239,3F4GV@33958,4HKCY@91061,COG3475@1,COG3475@2 NA|NA|NA M LicD family PGHMIELC_00232 220668.lp_0845 1.3e-82 312.4 Lactobacillaceae Bacteria 1V6TR@1239,3F66M@33958,4HXA8@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator PGHMIELC_00233 220668.lp_0846 1.6e-18 97.8 Lactobacillaceae Bacteria 1U6UM@1239,29PP3@1,30AM9@2,3F8IE@33958,4IGNF@91061 NA|NA|NA PGHMIELC_00234 220668.lp_0848 1.2e-225 788.9 Lactobacillaceae pbuG ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 1TQC6@1239,3F44D@33958,4HANG@91061,COG2252@1,COG2252@2 NA|NA|NA S permease PGHMIELC_00235 220668.lp_0849 0.0 1161.4 Lactobacillaceae poxB 1.2.3.3,1.2.5.1 ko:K00156,ko:K00158 ko00620,ko01100,map00620,map01100 R00207,R03145 RC00860,RC02745 ko00000,ko00001,ko01000 Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family PGHMIELC_00236 220668.lp_0850 7.8e-91 339.7 Lactobacillaceae ribF 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS06310 Bacteria 1V8DX@1239,3F6IA@33958,4HITY@91061,COG0196@1,COG0196@2 NA|NA|NA H Belongs to the ribF family PGHMIELC_00237 220668.lp_0852 0.0 1174.1 Lactobacillaceae poxB 1.2.3.3,1.2.5.1 ko:K00156,ko:K00158 ko00620,ko01100,map00620,map01100 R00207,R03145 RC00860,RC02745 ko00000,ko00001,ko01000 Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family PGHMIELC_00238 220668.lp_0853 5.4e-180 636.7 Lactobacillaceae pip 3.4.11.5 ko:K01259 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 1UEDT@1239,3F47H@33958,4HF61@91061,COG2267@1,COG2267@2 NA|NA|NA E Releases the N-terminal proline from various substrates PGHMIELC_00239 220668.lp_0854 2e-180 638.3 Lactobacillaceae birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 ko:K03524,ko:K04096 ko00780,ko01100,map00780,map01100 R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 Bacteria 1TQCU@1239,3F5HY@33958,4HB60@91061,COG0340@1,COG0340@2,COG1654@1,COG1654@2 NA|NA|NA H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor PGHMIELC_00240 220668.lp_0856 0.0 1161.4 Lactobacillaceae oatA GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016020,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 ko:K19172 ko00000,ko02048 Bacteria 1TPTG@1239,3F3WT@33958,4HB7R@91061,COG1835@1,COG1835@2,COG2755@1,COG2755@2 NA|NA|NA I Acyltransferase PGHMIELC_00241 220668.lp_0857 0.0 1658.7 Lactobacillaceae pepX 3.4.14.11 ko:K01281 ko00000,ko01000,ko01002 Bacteria 1TT78@1239,3F44E@33958,4HBA0@91061,COG2936@1,COG2936@2 NA|NA|NA E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline PGHMIELC_00242 220668.lp_0858 5e-69 266.9 Lactobacillaceae Bacteria 1VY9T@1239,3F7CX@33958,4HXI7@91061,COG1764@1,COG1764@2 NA|NA|NA O OsmC-like protein PGHMIELC_00243 220668.lp_0860 5.8e-46 189.9 Lactobacillaceae Bacteria 1U70S@1239,29PTD@1,30ARJ@2,3F8TP@33958,4IGV3@91061 NA|NA|NA PGHMIELC_00244 220668.lp_0861 8.2e-252 875.9 Lactobacillaceae yfnA ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3F3QY@33958,4HA66@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid PGHMIELC_00245 220668.lp_0862 2.5e-88 331.3 Lactobacillaceae Bacteria 1VFYC@1239,2DPIQ@1,3328X@2,3F5FA@33958,4HNHQ@91061 NA|NA|NA PGHMIELC_00246 220668.lp_0863 5.5e-147 526.9 Lactobacillaceae pdxK 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TRCR@1239,3F3V7@33958,4HHME@91061,COG2240@1,COG2240@2 NA|NA|NA H Phosphomethylpyrimidine kinase PGHMIELC_00247 220668.lp_0864 4.6e-73 280.4 Lactobacillaceae apfA 2.7.7.72,3.6.1.61 ko:K00974,ko:K18445 ko00230,ko03013,map00230,map03013 R00184,R09382,R09383,R09384,R09386 RC00002,RC00078 ko00000,ko00001,ko01000,ko03016 Bacteria 1VED7@1239,3FBDM@33958,4HRPV@91061,COG1051@1,COG1051@2 NA|NA|NA F Nudix hydrolase PGHMIELC_00248 220668.lp_0865 1.8e-19 100.9 Lactobacillaceae Bacteria 1W23H@1239,290AM@1,2ZN07@2,3F8TR@33958,4I028@91061 NA|NA|NA PGHMIELC_00249 220668.lp_0866 2e-103 381.7 Lactobacillaceae gmk2 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1V8PW@1239,3F6N3@33958,4HJCB@91061,COG0194@1,COG0194@2 NA|NA|NA F Guanylate kinase PGHMIELC_00250 220668.lp_0868 1.3e-81 308.9 Lactobacillaceae zur GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02076,ko:K03711 ko00000,ko03000 Bacteria 1V6RI@1239,3F6W3@33958,4HIGM@91061,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family PGHMIELC_00251 220668.lp_0869 7.1e-12 77.4 Lactobacillaceae 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 R01206,R02334 RC00467 ko00000,ko00001,ko01000 GH18 Bacteria 1VN2E@1239,2EQI3@1,33I43@2,3F860@33958,4HR4S@91061 NA|NA|NA PGHMIELC_00252 220668.lp_0871 4.9e-148 530.4 Lactobacillaceae Bacteria 1V7ET@1239,2C6F0@1,32RH8@2,3F4UC@33958,4HJDI@91061 NA|NA|NA PGHMIELC_00253 220668.lp_0872 8.8e-113 412.9 Lactobacillaceae gph 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1V7U6@1239,3F658@33958,4HJ9I@91061,COG0546@1,COG0546@2 NA|NA|NA S HAD hydrolase, family IA, variant PGHMIELC_00254 60520.HR47_04950 3e-210 737.6 Lactobacillaceae patA 2.6.1.1,2.6.1.57 ko:K00812,ko:K00832,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040,M00525 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R04467,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase PGHMIELC_00255 60520.HR47_04955 4.3e-170 604.0 Lactobacillaceae ldhD 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3F4US@33958,4HCIS@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family PGHMIELC_00256 220668.lp_0875 2e-39 167.9 Lactobacillaceae Bacteria 1W1YJ@1239,2900D@1,2ZMQP@2,3F8BQ@33958,4I01F@91061 NA|NA|NA PGHMIELC_00258 220668.lp_0878 9e-133 479.6 Lactobacillaceae glnQ 3.6.3.21 ko:K02028,ko:K10041 ko02010,map02010 M00228,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein PGHMIELC_00259 220668.lp_0881 7.8e-149 533.1 Lactobacillaceae glnH ko:K10039 ko02010,map02010 M00228 ko00000,ko00001,ko00002,ko02000 3.A.1.3 Bacteria 1TT11@1239,3F4GG@33958,4HAHV@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter substrate-binding protein PGHMIELC_00260 220668.lp_0882 1.6e-109 402.1 Lactobacillaceae gluC GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K10006,ko:K10040 ko02010,map02010 M00228,M00233 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.9 Bacteria 1TQ5K@1239,3F3XW@33958,4HFBH@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease PGHMIELC_00261 220668.lp_0883 4e-108 397.5 Lactobacillaceae glnP GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K02029,ko:K10002,ko:K10040 ko02010,ko02020,map02010,map02020 M00228,M00230,M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.19,3.A.1.3.4 Bacteria 1UJM4@1239,3F3WJ@33958,4HBAS@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease PGHMIELC_00262 220668.lp_0884 1e-84 319.3 Lactobacillaceae ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1 Bacteria 1VAEB@1239,3F7QW@33958,4I276@91061,COG2190@1,COG2190@2 NA|NA|NA G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PGHMIELC_00263 220668.lp_0885 4.7e-154 550.4 Lactobacillaceae ko:K02538,ko:K03488 ko00000,ko03000 Bacteria 1TS07@1239,3F40C@33958,4HUBU@91061,COG3711@1,COG3711@2 NA|NA|NA K CAT RNA binding domain PGHMIELC_00264 220668.lp_0886 1.8e-257 894.8 Lactobacillaceae 2.7.1.193,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02802,ko:K02803,ko:K02804,ko:K02808,ko:K02809,ko:K02810 ko00500,ko00520,ko02060,map00500,map00520,map02060 M00267,M00269,M00271 R00811,R05199 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TP5X@1239,3F4YU@33958,4HEWK@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2 NA|NA|NA G phosphotransferase system, EIIB PGHMIELC_00265 220668.lp_0887 8.4e-142 509.6 Lactobacillaceae Bacteria 1V4IM@1239,3F5B7@33958,4HG4E@91061,COG3394@1,COG3394@2 NA|NA|NA G YdjC-like protein PGHMIELC_00266 220668.lp_0888 2.1e-244 851.3 Lactobacillaceae steT GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ48@1239,3F3YJ@33958,4HBGT@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid PGHMIELC_00267 220668.lp_0889 4.8e-73 280.4 Lactobacillaceae mgrA GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 ko:K18906 M00700,M00702,M00704,M00717 ko00000,ko00002,ko01504,ko03000 Bacteria 1TTKG@1239,3F6NM@33958,4I358@91061,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein PGHMIELC_00268 220668.lp_0891 3.7e-149 534.3 Lactobacillaceae XK27_00825 ko:K07090 ko00000 Bacteria 1TQ8H@1239,3F4A6@33958,4IIWY@91061,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE PGHMIELC_00269 220668.lp_0892 2e-71 275.0 Lactobacillaceae Bacteria 1U6HM@1239,3F7XV@33958,4IG9X@91061,COG1846@1,COG1846@2 NA|NA|NA K MarR family PGHMIELC_00270 220668.lp_0893 2.4e-209 734.6 Lactobacillaceae Bacteria 1TQHD@1239,3FB93@33958,4HBCZ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_00271 220668.lp_0894 3.8e-85 320.9 Lactobacillaceae ko:K07090 ko00000 Bacteria 1V75K@1239,3F6BU@33958,4HEE8@91061,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein PGHMIELC_00272 220668.lp_0895 7.1e-98 363.2 Lactobacillaceae GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 Bacteria 1V847@1239,3F760@33958,4HI2V@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family PGHMIELC_00273 220668.lp_0896 8.7e-232 809.3 Lactobacillaceae hflX ko:K03665 ko00000,ko03009 Bacteria 1TNZB@1239,3F4B2@33958,4HACA@91061,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis PGHMIELC_00274 220668.lp_0897 9.9e-79 299.3 Lactobacillaceae 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1V5NQ@1239,3F66V@33958,4HH6Z@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain PGHMIELC_00275 220668.lp_0898 1.3e-48 198.7 Lactobacillaceae sugE ko:K11741 ko00000,ko02000 2.A.7.1 Bacteria 1VEZX@1239,3F7D6@33958,4HKXB@91061,COG2076@1,COG2076@2 NA|NA|NA U Multidrug resistance protein PGHMIELC_00276 220668.lp_0899 1.2e-26 125.2 Lactobacillaceae Bacteria 1W5SB@1239,28RTF@1,2ZE5S@2,3F873@33958,4HZIY@91061 NA|NA|NA PGHMIELC_00277 220668.lp_0900 3e-127 461.1 Lactobacillaceae pgm3 Bacteria 1TQWQ@1239,3F5XR@33958,4HFDZ@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family PGHMIELC_00278 220668.lp_0901 4.7e-125 453.8 Lactobacillaceae pgm3 Bacteria 1TQWQ@1239,3F524@33958,4HF2N@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family PGHMIELC_00279 220668.lp_0902 0.0 1097.0 Lactobacillaceae yjbQ ko:K03455,ko:K03499 ko00000,ko02000 2.A.37,2.A.38.1,2.A.38.4 Bacteria 1TS32@1239,3F4AZ@33958,4H9Q5@91061,COG0475@1,COG0475@2,COG0569@1,COG0569@2 NA|NA|NA P TrkA C-terminal domain protein PGHMIELC_00280 220668.lp_0903 3.1e-178 630.9 Lactobacillaceae yqkA 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1VFYN@1239,3FBDN@33958,4IPPU@91061,COG1051@1,COG1051@2,COG2320@1,COG2320@2 NA|NA|NA F Belongs to the Nudix hydrolase family PGHMIELC_00281 220668.lp_0904 1.9e-158 565.1 Lactobacillaceae bglG3 ko:K02538,ko:K03488 ko00000,ko03000 Bacteria 1TT5A@1239,3F4SJ@33958,4HC5Y@91061,COG3711@1,COG3711@2 NA|NA|NA K CAT RNA binding domain PGHMIELC_00282 220668.lp_0905 0.0 1136.3 Lactobacillaceae 2.7.1.193,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02802,ko:K02803,ko:K02804,ko:K02808,ko:K02809,ko:K02810 ko00500,ko00520,ko02060,map00500,map00520,map02060 M00267,M00269,M00271 R00811,R05199 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system PGHMIELC_00283 220668.lp_0906 2.5e-299 1033.9 Lactobacillaceae arbB 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family PGHMIELC_00284 220668.lp_0907 1.8e-108 398.7 Lactobacillaceae dedA ko:K03975 ko00000 Bacteria 1UZ4P@1239,3F51Q@33958,4HG3F@91061,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein PGHMIELC_00285 220668.lp_0910 0.0 1483.0 Lactobacillaceae helD 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP39@1239,3F486@33958,4H9Y5@91061,COG3973@1,COG3973@2 NA|NA|NA L DNA helicase PGHMIELC_00286 220668.lp_0912 1.7e-165 588.6 Lactobacillaceae fabK 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPC3@1239,3F4PC@33958,4H9T0@91061,COG2070@1,COG2070@2 NA|NA|NA S Nitronate monooxygenase PGHMIELC_00287 220668.lp_0913 1.2e-179 635.6 Lactobacillaceae coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECDH1ME8569_1439.ECDH1ME8569_3838,iECH74115_1262.ECH74115_5439,iECSE_1348.ECSE_4265,iECSF_1327.ECSF_3833,iECSP_1301.ECSP_5045,iECW_1372.ECW_m4332,iEcDH1_1363.EcDH1_4016,iEcolC_1368.EcolC_4046,iPC815.YPO3758,iSFV_1184.SFV_4047,iSFxv_1172.SFxv_4418,iWFL_1372.ECW_m4332,iZ_1308.Z5545 Bacteria 1TPHJ@1239,3F42Q@33958,4HA4K@91061,COG1072@1,COG1072@2 NA|NA|NA F Pantothenic acid kinase PGHMIELC_00288 220668.lp_0914 9.6e-302 1042.0 Lactobacillaceae guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 ko:K01951,ko:K03790 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002,ko03009 iJN746.PP_1032,iLJ478.TM1820,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833 Bacteria 1TPG8@1239,3F3NV@33958,4HA7Q@91061,COG0518@1,COG0518@2,COG0519@1,COG0519@2 NA|NA|NA F Catalyzes the synthesis of GMP from XMP PGHMIELC_00289 1133569.AHYZ01000154_gene2213 2.1e-100 371.7 Lactobacillaceae Bacteria 1TQSK@1239,3FBC6@33958,4HGQX@91061,COG5340@1,COG5340@2 NA|NA|NA K Transcriptional regulator, AbiEi antitoxin PGHMIELC_00290 220668.lp_0915 6.2e-50 203.4 Lactobacillaceae Bacteria 1VI51@1239,2E9BR@1,333JH@2,3F6MA@33958,4HQRQ@91061 NA|NA|NA PGHMIELC_00291 220668.lp_0917 1.7e-63 248.4 Lactobacillaceae Bacteria 1UUX6@1239,3F751@33958,4IFVS@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins PGHMIELC_00292 220668.lp_0918 0.0 1953.3 Lactobacillaceae Bacteria 1TQCB@1239,3F4YB@33958,4HBDJ@91061,COG1112@1,COG1112@2 NA|NA|NA L AAA domain PGHMIELC_00293 220668.lp_0919 1.1e-116 426.0 Bacteria XK27_07075 ko:K07052 ko00000 Bacteria COG1266@1,COG1266@2 NA|NA|NA V CAAX protease self-immunity PGHMIELC_00294 220668.lp_0921 1.4e-56 225.3 Lactobacillaceae hxlR Bacteria 1TTFM@1239,3F7DF@33958,4IE7T@91061,COG1733@1,COG1733@2 NA|NA|NA K HxlR-like helix-turn-helix PGHMIELC_00295 220668.lp_0922 1.4e-234 818.5 Lactobacillaceae Bacteria 1TS6K@1239,3F4X1@33958,4HB1V@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_00296 220668.lp_0923 2.2e-162 579.7 Lactobacillaceae Bacteria 1U59T@1239,3F5B3@33958,4IF1C@91061,COG2340@1,COG2340@2 NA|NA|NA S Cysteine-rich secretory protein family PGHMIELC_00297 1136177.KCA1_0740 2.9e-48 197.6 Lactobacillaceae Bacteria 1UI5S@1239,3F7G6@33958,4I3Y0@91061,COG1396@1,COG1396@2 NA|NA|NA K Cro/C1-type HTH DNA-binding domain PGHMIELC_00298 1136177.KCA1_0741 1.9e-65 257.7 Lactobacillaceae Bacteria 1W39C@1239,3F754@33958,4I0DV@91061,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation PGHMIELC_00299 220668.lp_0216 1.6e-31 142.1 Lactobacillaceae ko:K07487 ko00000 Bacteria 1TQQ9@1239,3F4M8@33958,4H9KK@91061,COG3666@1,COG3666@2 NA|NA|NA L Transposase PGHMIELC_00300 60520.HR47_05145 3.4e-66 258.1 Lactobacillaceae Bacteria 1U672@1239,29P6N@1,30A4S@2,3F789@33958,4IFXM@91061 NA|NA|NA PGHMIELC_00301 60520.HR47_05150 8.7e-153 546.6 Lactobacillaceae Bacteria 1VZSI@1239,29W71@1,30HS8@2,3F4M9@33958,4IEVP@91061 NA|NA|NA S Domain of unknown function (DUF4767) PGHMIELC_00302 60520.HR47_05155 1.9e-48 198.4 Lactobacillaceae Bacteria 1U7PK@1239,2AHKB@1,317Y4@2,3F9ZG@33958,4IHKX@91061 NA|NA|NA PGHMIELC_00303 220668.lp_0924 5.7e-38 163.7 Lactobacillaceae Bacteria 1UUX7@1239,3F6H6@33958,4I4CE@91061,COG4642@1,COG4642@2 NA|NA|NA S MORN repeat PGHMIELC_00304 220668.lp_0925 0.0 1161.0 Lactobacillaceae XK27_09800 ko:K19172 ko00000,ko02048 Bacteria 1U6DU@1239,3F3MH@33958,4H9XT@91061,COG1835@1,COG1835@2,COG2755@1,COG2755@2 NA|NA|NA I Acyltransferase family PGHMIELC_00305 220668.lp_0926 7.1e-37 159.5 Lactobacillaceae Bacteria 1VENK@1239,3F7EK@33958,4HNKV@91061,COG2261@1,COG2261@2 NA|NA|NA S Transglycosylase associated protein PGHMIELC_00306 220668.lp_0927 2.6e-84 318.2 Lactobacillaceae Bacteria 1UH2V@1239,29VKQ@1,30H3Q@2,3F633@33958,4IFA9@91061 NA|NA|NA PGHMIELC_00307 220668.lp_0928 7.2e-23 112.5 Lactobacillaceae Bacteria 1U6U3@1239,29PNK@1,30AKT@2,3F8HM@33958,4IGMX@91061 NA|NA|NA PGHMIELC_00308 220668.lp_0929 8.7e-72 276.2 Lactobacillaceae asp Bacteria 1V8FM@1239,3F77J@33958,4HJ0H@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function PGHMIELC_00309 220668.lp_0930 5.3e-72 276.9 Lactobacillaceae asp2 Bacteria 1VJRA@1239,3F692@33958,4HXJN@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function PGHMIELC_00310 220668.lp_0931 2.6e-149 534.6 Lactobacillaceae Bacteria 1TQDQ@1239,3F585@33958,4HCBR@91061,COG0179@1,COG0179@2 NA|NA|NA Q Fumarylacetoacetate (FAA) hydrolase family PGHMIELC_00311 60520.HR47_05200 2.7e-156 558.1 Lactobacillaceae yjdB Bacteria 1VFT3@1239,2DMBI@1,32H42@2,3F7XU@33958,4HK1A@91061 NA|NA|NA S Domain of unknown function (DUF4767) PGHMIELC_00312 220668.lp_0934 5.3e-48 196.8 Lactobacillaceae 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 Bacteria 1U69A@1239,3F7CF@33958,4IG0F@91061,COG1447@1,COG1447@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIA subunit PGHMIELC_00313 220668.lp_0935 4.1e-101 374.0 Lactobacillaceae Bacteria 1TWD3@1239,3F54W@33958,4I54S@91061,COG3408@1,COG3408@2 NA|NA|NA G Glycogen debranching enzyme PGHMIELC_00314 220668.lp_0937 0.0 1645.2 Lactobacillaceae pepN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 1TR43@1239,3F3UH@33958,4HA20@91061,COG0308@1,COG0308@2 NA|NA|NA E aminopeptidase PGHMIELC_00315 220668.lp_0938 0.0 1897.5 Lactobacillaceae hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 1TP7S@1239,3F50Q@33958,4HB5A@91061,COG0610@1,COG0610@2 NA|NA|NA V Subunit R is required for both nuclease and ATPase activities, but not for modification PGHMIELC_00316 220668.lp_0939 6.5e-60 236.5 Lactobacillaceae hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1TPGZ@1239,3F4HM@33958,4HA1J@91061,COG0286@1,COG0286@2 NA|NA|NA V type I restriction-modification system PGHMIELC_00317 220668.lp_0939 2.6e-219 767.7 Lactobacillaceae hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1TPGZ@1239,3F4HM@33958,4HA1J@91061,COG0286@1,COG0286@2 NA|NA|NA V type I restriction-modification system PGHMIELC_00318 220668.lp_0940 2.8e-09 67.8 Lactobacillaceae hsdS 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1TP5N@1239,3F718@33958,4HUTA@91061,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain PGHMIELC_00319 1114972.AUAW01000025_gene777 1.1e-65 256.9 Lactobacillaceae 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1TP5N@1239,3FB4X@33958,4HGJM@91061,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain PGHMIELC_00320 220668.lp_0941 1.1e-169 602.4 Lactobacillaceae Bacteria 1TPE1@1239,3F3NJ@33958,4HA65@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family PGHMIELC_00321 1314.HKU360_01745 3.4e-51 208.0 Bacilli hsdS 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1TP5N@1239,4HFAV@91061,COG0732@1,COG0732@2 NA|NA|NA V type I restriction modification DNA specificity domain protein PGHMIELC_00322 220668.lp_0945 1e-90 339.3 Lactobacillaceae XK27_09665 5.4.2.11 ko:K01834,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1VCU1@1239,3F76I@33958,4HQY2@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family PGHMIELC_00323 220668.lp_0946 0.0 1686.4 Lactobacillaceae nagH 2.7.13.3,3.2.1.4,3.2.1.52,3.2.1.78,3.2.1.8 ko:K01179,ko:K01181,ko:K01218,ko:K02476,ko:K12373 ko00051,ko00500,ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko02024,ko04142,map00051,map00500,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map02024,map04142 M00079 R00022,R01332,R06004,R06200,R11307,R11308,R11316 RC00049,RC00467 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03110 GH20,GH26,GH5,GH9 Bacteria 1UWF2@1239,3F6D1@33958,4HGU0@91061,COG4886@1,COG4886@2,COG4932@1,COG4932@2 NA|NA|NA M MucBP domain PGHMIELC_00325 220668.lp_0948 3.5e-88 330.9 Lactobacillaceae Bacteria 1UIME@1239,3F6E7@33958,4ISNB@91061,COG0645@1,COG0645@2 NA|NA|NA S AAA domain PGHMIELC_00326 220668.lp_0949 4.5e-140 503.8 Lactobacillaceae Bacteria 1V873@1239,3F762@33958,4HQNH@91061,COG1396@1,COG1396@2 NA|NA|NA K sequence-specific DNA binding PGHMIELC_00327 220668.lp_0950 2.3e-96 358.2 Firmicutes Bacteria 1UIXC@1239,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix domain PGHMIELC_00328 220668.lp_0951 6.1e-171 606.7 Lactobacillaceae Bacteria 1TTAM@1239,3FC6M@33958,4HFT5@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator PGHMIELC_00329 220668.lp_0952 0.0 1244.6 Lactobacillaceae 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 1UZHI@1239,3F4A4@33958,4I3MZ@91061,COG1053@1,COG1053@2,COG3976@1,COG3976@2 NA|NA|NA C FMN_bind PGHMIELC_00331 220668.lp_0954 2.3e-81 308.1 Lactobacillaceae rmaD Bacteria 1V4SH@1239,3FC7I@33958,4HICC@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator PGHMIELC_00332 220668.lp_0955 4.2e-115 420.6 Lactobacillaceae azoR GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008081,GO:0008150,GO:0008152,GO:0008770,GO:0009987,GO:0016787,GO:0016788,GO:0019752,GO:0032787,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704,GO:0140096 ko:K01118 ko00000,ko01000 Bacteria 1UGCK@1239,3FBBW@33958,4HAPQ@91061,COG1182@1,COG1182@2 NA|NA|NA I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity PGHMIELC_00333 220668.lp_0956 1.1e-253 882.1 Lactobacillaceae asnS GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP38@1239,3F4EK@33958,4H9YH@91061,COG0017@1,COG0017@2 NA|NA|NA J Asparaginyl-tRNA synthetase PGHMIELC_00334 60520.HR47_09275 9.9e-199 699.1 Lactobacillaceae asnA GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 R00483 RC00010 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299 Bacteria 1TP28@1239,3F40A@33958,4HAEC@91061,COG2502@1,COG2502@2 NA|NA|NA F aspartate--ammonia ligase PGHMIELC_00335 220668.lp_0959 7.4e-277 959.1 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase PGHMIELC_00336 220668.lp_0960 1.7e-221 775.0 Lactobacillaceae 2.7.7.7,3.6.4.12 ko:K02342,ko:K03722 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1U55Z@1239,3F4VS@33958,4IEXD@91061,COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease PGHMIELC_00337 220668.lp_0960a 8.5e-41 172.6 Lactobacillaceae Bacteria 1U6BK@1239,29PA4@1,30A89@2,3F7IZ@33958,4IG38@91061 NA|NA|NA PGHMIELC_00338 220668.lp_0961 4.1e-32 143.3 Lactobacillaceae Bacteria 1U6HT@1239,3F7Y2@33958,4IGA4@91061,COG3415@1,COG3415@2 NA|NA|NA L leucine-zipper of insertion element IS481 PGHMIELC_00339 220668.lp_0962 0.0 1182.2 Lactobacillaceae recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPN5@1239,3F4PY@33958,4H9QP@91061,COG0514@1,COG0514@2 NA|NA|NA L ATP-dependent DNA helicase RecQ PGHMIELC_00340 220668.lp_0963 2.9e-162 577.8 Lactobacillaceae rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1TS1T@1239,3F46Z@33958,4HBRY@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil PGHMIELC_00341 220668.lp_0965 1.5e-50 205.3 Lactobacillaceae ko:K03892 ko00000,ko03000 Bacteria 1U625@1239,3F6UW@33958,4IFR5@91061,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor PGHMIELC_00342 220668.lp_0966 1.3e-137 495.7 Lactobacillaceae Bacteria 1VBJA@1239,3F41J@33958,4HSVK@91061,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase PGHMIELC_00343 220668.lp_0967 2.3e-179 634.8 Lactobacillaceae Bacteria 1U5GW@1239,29NS0@1,309Q0@2,3F5X3@33958,4IF7N@91061 NA|NA|NA PGHMIELC_00344 220668.lp_0968 1.9e-220 771.5 Lactobacillaceae yibE Bacteria 1TPEV@1239,3F3M9@33958,4HCP3@91061,COG5438@1,COG5438@2 NA|NA|NA S overlaps another CDS with the same product name PGHMIELC_00345 220668.lp_0969 1.3e-126 459.1 Lactobacillaceae yibF Bacteria 1TSWX@1239,3F3S6@33958,4HBKX@91061,COG5438@1,COG5438@2 NA|NA|NA S overlaps another CDS with the same product name PGHMIELC_00346 220668.lp_0970 2.6e-103 381.3 Lactobacillaceae 3.2.2.20 ko:K01246,ko:K06977 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1UFIT@1239,3F3Y5@33958,4IESW@91061,COG0454@1,COG0456@2 NA|NA|NA K FR47-like protein PGHMIELC_00347 220668.lp_0971 5e-122 443.7 Lactobacillaceae pgm6 5.4.2.11,5.4.2.12 ko:K01834,ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1V6ES@1239,3F4IS@33958,4HGZI@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family PGHMIELC_00348 220668.lp_0972 5.6e-49 199.9 Lactobacillaceae Bacteria 1U62P@1239,2DKNE@1,30A1I@2,3F6W0@33958,4IFRU@91061 NA|NA|NA PGHMIELC_00349 220668.lp_0973 1.3e-190 672.2 Lactobacillaceae nlhH_1 ko:K01066 ko00000,ko01000 Bacteria 1TQHX@1239,3F5CV@33958,4HGC2@91061,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold PGHMIELC_00350 220668.lp_0975 1.5e-253 881.7 Lactobacillaceae xylP2 ko:K03292,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.2 Bacteria 1TRA5@1239,3F3Z2@33958,4HBAI@91061,COG2211@1,COG2211@2 NA|NA|NA G symporter PGHMIELC_00351 220668.lp_0977 5.2e-281 973.0 Lactobacillaceae murE 6.3.2.10,6.3.2.13,6.3.2.7 ko:K01928,ko:K05362,ko:K15792 ko00300,ko00550,ko01100,map00300,map00550,map01100 R02786,R02788,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TPQE@1239,3F3UE@33958,4H9T1@91061,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan PGHMIELC_00352 220668.lp_0979 1.6e-219 768.5 Lactobacillaceae dapG GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 ko:K00928,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPQJ@1239,3F4V2@33958,4HADX@91061,COG0527@1,COG0527@2 NA|NA|NA E Amino acid kinase family PGHMIELC_00353 220668.lp_0980 0.0 1305.4 Lactobacillaceae asnB GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 1TRPB@1239,3F3NT@33958,4HAIP@91061,COG0367@1,COG0367@2 NA|NA|NA E Asparagine synthase PGHMIELC_00354 220668.lp_0981 7.2e-50 203.0 Lactobacillaceae azlD Bacteria 1VH9Q@1239,3F7IU@33958,4HNDZ@91061,COG4392@1,COG4392@2 NA|NA|NA S Branched-chain amino acid transport protein (AzlD) PGHMIELC_00355 220668.lp_0982 1.3e-120 439.1 Lactobacillaceae azlC Bacteria 1U49T@1239,3F45S@33958,4HDIJ@91061,COG1296@1,COG1296@2 NA|NA|NA E branched-chain amino acid PGHMIELC_00356 220668.lp_0984 4.4e-35 153.3 Lactobacillaceae yyaN Bacteria 1U69E@1239,3F7CS@33958,4IG0J@91061,COG0789@1,COG0789@2 NA|NA|NA K MerR HTH family regulatory protein PGHMIELC_00357 220668.lp_0988 3.8e-106 391.7 Lactobacillaceae Bacteria 1U5DG@1239,2DKJ2@1,309ND@2,3F5MM@33958,4IF4T@91061 NA|NA|NA PGHMIELC_00358 220668.lp_0990 1.4e-117 429.1 Lactobacillaceae Bacteria 1VDDQ@1239,2C9UQ@1,32RPZ@2,3F5X9@33958,4HNJB@91061 NA|NA|NA S Domain of unknown function (DUF4811) PGHMIELC_00359 220668.lp_0991 7e-270 936.0 Lactobacillaceae lmrB Bacteria 1TPRN@1239,3F4A2@33958,4H9VV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_00360 220668.lp_0992 1.7e-84 318.5 Lactobacillaceae merR ko:K21089,ko:K21972,ko:K22491 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 1VZ9X@1239,3FBR0@33958,4HYI3@91061,COG0789@1,COG0789@2 NA|NA|NA K MerR HTH family regulatory protein PGHMIELC_00361 220668.lp_0995 2.6e-58 231.1 Lactobacillaceae Bacteria 1U708@1239,29PSZ@1,30AR5@2,3F8T2@33958,4IGUJ@91061 NA|NA|NA PGHMIELC_00362 220668.lp_0996 2e-120 438.3 Lactobacillaceae sirR ko:K03709 ko00000,ko03000 Bacteria 1V3IS@1239,3F405@33958,4HH06@91061,COG1321@1,COG1321@2 NA|NA|NA K iron dependent repressor PGHMIELC_00363 220668.lp_0997 6e-31 139.4 Lactobacillaceae cspC ko:K03704 ko00000,ko03000 Bacteria 1VEE0@1239,3F7FW@33958,4HNJC@91061,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein PGHMIELC_00364 220668.lp_0998 1.5e-130 472.2 Lactobacillaceae thrE Bacteria 1TSE8@1239,3F4XE@33958,4HBW1@91061,COG2966@1,COG2966@2 NA|NA|NA S Putative threonine/serine exporter PGHMIELC_00365 220668.lp_0999 2.2e-76 291.6 Lactobacillaceae Bacteria 1V6P0@1239,3F63I@33958,4HJ1Y@91061,COG3610@1,COG3610@2 NA|NA|NA S Threonine/Serine exporter, ThrE PGHMIELC_00366 220668.lp_1000 1.5e-189 668.7 Lactobacillaceae brpA Bacteria 1TR1B@1239,3F3MQ@33958,4HA09@91061,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-like function transcriptional attenuator common domain protein PGHMIELC_00367 220668.lp_1001 2.3e-119 434.9 Lactobacillaceae lssY 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1VY85@1239,3F4DD@33958,4HXM4@91061,COG0671@1,COG0671@2 NA|NA|NA I phosphatase PGHMIELC_00368 220668.lp_1002 2e-154 551.6 Lactobacillaceae Bacteria 1V7DQ@1239,3FBDR@33958,4HK24@91061,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold PGHMIELC_00369 220668.lp_1003 2.8e-99 367.9 Lactobacillaceae 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 1V49W@1239,3F5A6@33958,4HHAP@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain PGHMIELC_00370 220668.lp_1004 4.2e-92 344.0 Lactobacillaceae Bacteria 1VAMC@1239,3F4Y9@33958,4HN90@91061,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator PGHMIELC_00371 220668.lp_1005 0.0 1104.7 Lactobacillaceae alsS 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQE8@1239,3FCE6@33958,4HAV1@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family PGHMIELC_00372 220668.lp_1008 1.5e-264 918.3 Lactobacillaceae lysP ko:K03293,ko:K11733,ko:K16235 ko00000,ko02000 2.A.3.1,2.A.3.1.10,2.A.3.1.2 Bacteria 1UHNR@1239,3F4BG@33958,4HUT7@91061,COG0833@1,COG0833@2 NA|NA|NA E amino acid PGHMIELC_00373 220668.lp_1010 2.5e-114 418.3 Lactobacillaceae vanY 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Bacteria 1V6U8@1239,3F5PF@33958,4HJCV@91061,COG1876@1,COG1876@2 NA|NA|NA M D-alanyl-D-alanine carboxypeptidase PGHMIELC_00374 220668.lp_1011 2.5e-115 421.4 Lactobacillaceae dak 2.7.1.74,2.7.1.76 ko:K00893,ko:K10353 ko00230,ko00240,ko01100,map00230,map00240,map01100 R00185,R01666,R02089 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TPJ1@1239,3F488@33958,4HA9N@91061,COG1428@1,COG1428@2 NA|NA|NA F deoxynucleoside kinase PGHMIELC_00375 220668.lp_1012 4.1e-218 763.8 Lactobacillaceae serS GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF987.Gmet_3528,iSDY_1059.SDY_2368 Bacteria 1TP4W@1239,3F3M6@33958,4H9Y4@91061,COG0172@1,COG0172@2 NA|NA|NA J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) PGHMIELC_00383 220668.lp_1018 6.9e-78 296.6 Lactobacillaceae ctsR GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 ko:K03708 ko00000,ko03000 Bacteria 1VAXT@1239,3F53E@33958,4HIFT@91061,COG4463@1,COG4463@2 NA|NA|NA K Belongs to the CtsR family PGHMIELC_00384 60520.HR47_09535 0.0 1568.9 Lactobacillaceae clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 1TPMU@1239,3F3RV@33958,4HACY@91061,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE PGHMIELC_00385 220668.lp_1020 7.4e-109 399.8 Lactobacillaceae ko:K09017 ko00000,ko03000 Bacteria 1VD4H@1239,3F5VC@33958,4HNBF@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family PGHMIELC_00386 60520.HR47_09545 0.0 2369.7 Lactobacillaceae rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TP96@1239,3F4ET@33958,4H9PK@91061,COG0085@1,COG0085@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates PGHMIELC_00387 220668.lp_1022 0.0 2405.2 Lactobacillaceae rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TNYT@1239,3F3KF@33958,4HA24@91061,COG0086@1,COG0086@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates PGHMIELC_00388 220668.lp_1023 7.8e-115 419.9 Lactobacillaceae pilD 3.4.23.43 ko:K02236,ko:K02506,ko:K02654 M00331,M00429 ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 Bacteria 1W118@1239,3F863@33958,4HZ6B@91061,COG1989@1,COG1989@2 NA|NA|NA NOU Bacterial Peptidase A24 N-terminal domain PGHMIELC_00389 220668.lp_1025 3.6e-70 270.8 Lactobacillaceae rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02950 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1FJ@1239,3F64B@33958,4HFMZ@91061,COG0048@1,COG0048@2 NA|NA|NA J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit PGHMIELC_00390 1136177.KCA1_0815 5.5e-83 313.5 Lactobacillaceae rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02992 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1GG@1239,3F3RX@33958,4H9PA@91061,COG0049@1,COG0049@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA PGHMIELC_00391 220668.lp_1027 0.0 1381.7 Lactobacillaceae fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02355 ko00000,ko03012,ko03029 Bacteria 1TPF9@1239,3F3JR@33958,4HAB8@91061,COG0480@1,COG0480@2 NA|NA|NA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome PGHMIELC_00392 1136177.KCA1_0817 2.6e-49 201.1 Lactobacillaceae rpsJ GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 ko:K02946 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6C9@1239,3F6KC@33958,4HIKH@91061,COG0051@1,COG0051@2 NA|NA|NA J Involved in the binding of tRNA to the ribosomes PGHMIELC_00393 220668.lp_1033 4.4e-112 410.6 Lactobacillaceae rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 ko:K02906 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPFT@1239,3F45I@33958,4HAEN@91061,COG0087@1,COG0087@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit PGHMIELC_00394 220668.lp_1034 5.5e-107 393.7 Lactobacillaceae rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02926,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPGW@1239,3F3QD@33958,4HB01@91061,COG0088@1,COG0088@2 NA|NA|NA J Forms part of the polypeptide exit tunnel PGHMIELC_00395 220668.lp_1035 1.8e-44 184.9 Lactobacillaceae rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02892 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VA4W@1239,3F6Z2@33958,4HKCV@91061,COG0089@1,COG0089@2 NA|NA|NA J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome PGHMIELC_00396 220668.lp_1036 8.1e-146 523.1 Lactobacillaceae rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02886 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TP9X@1239,3F3XI@33958,4HAE8@91061,COG0090@1,COG0090@2 NA|NA|NA J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity PGHMIELC_00397 1136177.KCA1_0822 8.2e-47 192.6 Lactobacillaceae rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02965 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6CX@1239,3F6XP@33958,4HIG0@91061,COG0185@1,COG0185@2 NA|NA|NA J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA PGHMIELC_00398 1136177.KCA1_0823 2.8e-52 211.1 Lactobacillaceae rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02890 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6PU@1239,3F6K6@33958,4HIK2@91061,COG0091@1,COG0091@2 NA|NA|NA J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome PGHMIELC_00399 1136177.KCA1_0824 2.1e-117 428.3 Lactobacillaceae rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02982 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPCP@1239,3F3Q8@33958,4HAUR@91061,COG0092@1,COG0092@2 NA|NA|NA J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation PGHMIELC_00400 220668.lp_1041 9.2e-77 292.7 Lactobacillaceae rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02878 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1AY@1239,3F653@33958,4HFPN@91061,COG0197@1,COG0197@2 NA|NA|NA J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs PGHMIELC_00401 1136177.KCA1_0826 1.4e-24 118.2 Lactobacillaceae rpmC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02904 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEME@1239,3F82Z@33958,4HNUP@91061,COG0255@1,COG0255@2 NA|NA|NA J Belongs to the universal ribosomal protein uL29 family PGHMIELC_00402 1136177.KCA1_0827 2.5e-40 171.0 Lactobacillaceae rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02961 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9YC@1239,3F7FX@33958,4HKDN@91061,COG0186@1,COG0186@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA PGHMIELC_00403 220668.lp_1045 4.3e-59 233.8 Lactobacillaceae rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02874 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3N0@1239,3F6GT@33958,4HGYR@91061,COG0093@1,COG0093@2 NA|NA|NA J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome PGHMIELC_00404 220668.lp_1046 2.4e-50 204.5 Lactobacillaceae rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02895 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9ZQ@1239,3F6X5@33958,4HKH9@91061,COG0198@1,COG0198@2 NA|NA|NA J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit PGHMIELC_00405 1136177.KCA1_0830 3.2e-95 354.4 Lactobacillaceae rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02931 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPE0@1239,3F3Q7@33958,4HBAX@91061,COG0094@1,COG0094@2 NA|NA|NA J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits PGHMIELC_00406 1136177.KCA1_0832 1e-66 259.2 Lactobacillaceae rpsH GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904 ko:K02994 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3KK@1239,3F64E@33958,4HH32@91061,COG0096@1,COG0096@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit PGHMIELC_00407 220668.lp_1051 3.5e-94 350.9 Lactobacillaceae rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02933 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1FC@1239,3F4G5@33958,4HFQD@91061,COG0097@1,COG0097@2 NA|NA|NA J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center PGHMIELC_00408 220668.lp_1052 3.3e-56 224.2 Lactobacillaceae rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02881 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6DM@1239,3F6KN@33958,4HIGF@91061,COG0256@1,COG0256@2 NA|NA|NA J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance PGHMIELC_00409 1136177.KCA1_0835 6.8e-84 316.6 Lactobacillaceae rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02988 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1B1@1239,3F3VY@33958,4HFN4@91061,COG0098@1,COG0098@2 NA|NA|NA J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body PGHMIELC_00410 220668.lp_1054 2.2e-24 117.5 Lactobacillaceae rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02907 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEG4@1239,3F7ZU@33958,4HNHF@91061,COG1841@1,COG1841@2 NA|NA|NA J Ribosomal protein L30 PGHMIELC_00411 1136177.KCA1_0837 6.3e-70 270.0 Lactobacillaceae rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02876 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3KE@1239,3F675@33958,4HFPW@91061,COG0200@1,COG0200@2 NA|NA|NA J Binds to the 23S rRNA PGHMIELC_00412 220668.lp_1056 1.5e-236 825.1 Lactobacillaceae secY GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0040007,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5 Bacteria 1TPHB@1239,3F4FV@33958,4HAWH@91061,COG0201@1,COG0201@2 NA|NA|NA U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently PGHMIELC_00413 220668.lp_1058 2.1e-125 454.9 Lactobacillaceae adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS20110 Bacteria 1TP27@1239,3F3KB@33958,4HA89@91061,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism PGHMIELC_00414 1136177.KCA1_0840 3.1e-33 147.1 Lactobacillaceae infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009986,GO:0016020,GO:0030246,GO:0030247,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 1V9ZK@1239,3F7CW@33958,4HKF4@91061,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex PGHMIELC_00415 220668.lp_1060 1.1e-59 235.7 Lactobacillaceae rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02952 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3JH@1239,3F6GN@33958,4HGX6@91061,COG0099@1,COG0099@2 NA|NA|NA J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits PGHMIELC_00416 1400520.LFAB_04735 3.4e-62 244.2 Lactobacillaceae rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02948 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3IK@1239,3F67D@33958,4HH2T@91061,COG0100@1,COG0100@2 NA|NA|NA J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome PGHMIELC_00417 220668.lp_1062 5.7e-172 610.1 Lactobacillaceae rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TPR8@1239,3F3W6@33958,4H9R1@91061,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates PGHMIELC_00418 220668.lp_1063 2.1e-61 241.5 Lactobacillaceae rplQ GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02879,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6JQ@1239,3F6GJ@33958,4HGX2@91061,COG0203@1,COG0203@2 NA|NA|NA J Ribosomal protein L17 PGHMIELC_00419 220668.lp_1066 1.4e-181 642.1 Lactobacillaceae hepT 2.5.1.30,2.5.1.90 ko:K00805,ko:K02523 ko00900,ko01110,map00900,map01110 R09247,R09248 RC00279 ko00000,ko00001,ko01000,ko01006 Bacteria 1TR0U@1239,3F4GC@33958,4H9RH@91061,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family PGHMIELC_00420 220668.lp_1067 1.7e-94 352.1 Lactobacillaceae gerCA 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 R09247 RC00279 ko00000,ko00001,ko01000,ko01006 Bacteria 1V1M0@1239,3F3R8@33958,4HG1H@91061,COG4769@1,COG4769@2 NA|NA|NA S Heptaprenyl diphosphate synthase component I PGHMIELC_00421 220668.lp_1068 1.4e-86 325.5 Lactobacillaceae ynhH Bacteria 1VCR8@1239,3F7R1@33958,4HMR5@91061,COG5341@1,COG5341@2 NA|NA|NA S NusG domain II PGHMIELC_00422 220668.lp_1069 0.0 1256.5 Lactobacillaceae ndh 1.6.99.3 ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1TR6X@1239,3F4N1@33958,4HA14@91061,COG1252@1,COG1252@2 NA|NA|NA C NADH dehydrogenase PGHMIELC_00423 220668.lp_1070 3.5e-142 511.1 Lactobacillaceae cad ko:K20379 ko02024,map02024 ko00000,ko00001 Bacteria 1V3CW@1239,3F5C4@33958,4IR0T@91061,COG4939@1,COG4939@2 NA|NA|NA S FMN_bind PGHMIELC_00424 220668.lp_1072 1.5e-208 731.9 Lactobacillaceae apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 1TR9C@1239,3FB4B@33958,4HA6Y@91061,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein PGHMIELC_00425 220668.lp_1073 1.4e-153 548.9 Lactobacillaceae ecfA1 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 ko:K16784,ko:K16786,ko:K16787 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPH8@1239,3F3VD@33958,4H9R8@91061,COG1122@1,COG1122@2 NA|NA|NA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates PGHMIELC_00426 220668.lp_1074 8.2e-165 586.3 Lactobacillaceae ecfA2 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008144,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032217,GO:0032218,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035461,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0097159,GO:0097367,GO:0098656,GO:1901265,GO:1901363 3.6.3.55 ko:K02068,ko:K06857,ko:K16784,ko:K16786,ko:K16787 ko02010,map02010 M00186,M00211,M00581,M00582 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35,3.A.1.6.2,3.A.1.6.4 Bacteria 1TPH8@1239,3F48E@33958,4HA7T@91061,COG1122@1,COG1122@2 NA|NA|NA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates PGHMIELC_00427 220668.lp_1075 4.7e-143 513.8 Lactobacillaceae ecfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 ko:K02008,ko:K16783,ko:K16785 ko02010,map02010 M00245,M00246,M00581,M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TQ0E@1239,3F3UW@33958,4H9VT@91061,COG0619@1,COG0619@2 NA|NA|NA U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates PGHMIELC_00428 220668.lp_1076 3.9e-150 537.3 Lactobacillaceae truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 1TQUY@1239,3F4KC@33958,4HCFI@91061,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs PGHMIELC_00429 1136177.KCA1_0856 1.3e-78 298.9 Lactobacillaceae rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3HX@1239,3F696@33958,4HG0I@91061,COG0102@1,COG0102@2 NA|NA|NA J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly PGHMIELC_00430 1136177.KCA1_0857 1.9e-65 255.0 Lactobacillaceae rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3MQ@1239,3F656@33958,4HH3B@91061,COG0103@1,COG0103@2 NA|NA|NA J Belongs to the universal ribosomal protein uS9 family PGHMIELC_00431 220668.lp_1079 4e-164 583.9 Lactobacillaceae degV Bacteria 1TQDI@1239,3F4II@33958,4HAYQ@91061,COG1307@1,COG1307@2 NA|NA|NA S Uncharacterised protein, DegV family COG1307 PGHMIELC_00432 220668.lp_1081 3.7e-183 647.5 Lactobacillaceae ywhK Bacteria 1V841@1239,3F50M@33958,4HITC@91061,COG3391@1,COG3391@2 NA|NA|NA S Membrane PGHMIELC_00433 220668.lp_1082 4.2e-203 713.8 Lactobacillaceae mdh 1.1.1.350 ko:K00073 ko00230,ko01120,map00230,map01120 R02935,R02936 RC00169 ko00000,ko00001,ko01000 Bacteria 1TR0Z@1239,3F4JZ@33958,4HB6X@91061,COG2055@1,COG2055@2 NA|NA|NA C Belongs to the LDH2 MDH2 oxidoreductase family PGHMIELC_00434 220668.lp_1083 0.0 1302.0 Lactobacillaceae tkt 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPIB@1239,3F4IJ@33958,4HADA@91061,COG0021@1,COG0021@2 NA|NA|NA H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate PGHMIELC_00435 220668.lp_1084 8.3e-165 586.3 Lactobacillaceae aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQRY@1239,3F4WM@33958,4HD4R@91061,COG0169@1,COG0169@2 NA|NA|NA E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) PGHMIELC_00436 220668.lp_1085 1.8e-184 651.7 Lactobacillaceae aroF 2.5.1.54 ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP61@1239,3F5B5@33958,4HB03@91061,COG2876@1,COG2876@2 NA|NA|NA E DAHP synthetase I family PGHMIELC_00437 220668.lp_1086 4.9e-196 690.3 Lactobacillaceae aroB 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPKZ@1239,3F4JH@33958,4HAKN@91061,COG0337@1,COG0337@2 NA|NA|NA E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) PGHMIELC_00438 220668.lp_1087 4.7e-263 913.3 Lactobacillaceae ko:K03319 ko00000 2.A.47 Bacteria 1TSGE@1239,3F4RH@33958,4HDE4@91061,COG0471@1,COG0471@2 NA|NA|NA P Sodium:sulfate symporter transmembrane region PGHMIELC_00439 220668.lp_1088 4.1e-53 213.8 Lactobacillaceae yitW ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1V9YV@1239,3F7D5@33958,4HKC6@91061,COG2151@1,COG2151@2 NA|NA|NA S Iron-sulfur cluster assembly protein PGHMIELC_00440 220668.lp_1089 5.4e-115 420.2 Bacilli ttdB GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896 4.2.1.2,4.2.1.32 ko:K01678,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00339,R01082 RC00443,RC01382 ko00000,ko00001,ko00002,ko01000 iSBO_1134.SBO_2920 Bacteria 1TSJ8@1239,4HHKR@91061,COG1838@1,COG1838@2 NA|NA|NA C Catalyzes the reversible hydration of fumarate to (S)- malate PGHMIELC_00441 220668.lp_1090 2.2e-176 624.8 Lactobacillaceae ttdA GO:0008150,GO:0008152,GO:1901275 4.2.1.32 ko:K03779 ko00630,map00630 R00339 RC01382 ko00000,ko00001,ko01000 iLF82_1304.LF82_2330 Bacteria 1TPXQ@1239,3F5FD@33958,4HA3C@91061,COG1951@1,COG1951@2 NA|NA|NA C Fumarate hydratase (Fumerase) PGHMIELC_00442 220668.lp_1092 1.7e-198 698.4 Lactobacillaceae Bacteria 1V27P@1239,3F65V@33958,4I2JJ@91061,COG1917@1,COG1917@2,COG2207@1,COG2207@2 NA|NA|NA K Helix-turn-helix domain PGHMIELC_00443 220668.lp_1093 2.4e-153 548.1 Lactobacillaceae citG 2.4.2.52,2.7.7.61 ko:K05966,ko:K13927,ko:K13930 ko02020,map02020 R09675,R10706 RC00049,RC00063 ko00000,ko00001,ko01000 Bacteria 1TQGQ@1239,3F4SU@33958,4HGCS@91061,COG1767@1,COG1767@2 NA|NA|NA H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase PGHMIELC_00444 220668.lp_1095 4.5e-132 477.2 Lactobacillaceae mntB 3.6.3.35 ko:K01990,ko:K02074,ko:K11710,ko:K19973 ko02010,map02010 M00244,M00254,M00319,M00792 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.15,3.A.1.15.15 Bacteria 1TQJ3@1239,3F4VW@33958,4HA2W@91061,COG1121@1,COG1121@2 NA|NA|NA P ABC transporter PGHMIELC_00445 220668.lp_1096 4.8e-141 507.3 Lactobacillaceae mtsB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 ko:K09819,ko:K19975,ko:K19976 ko02010,map02010 M00243,M00792 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.15 Bacteria 1TPZB@1239,3F4JM@33958,4HBD7@91061,COG1108@1,COG1108@2 NA|NA|NA U ABC 3 transport family PGHMIELC_00446 220668.lp_1097 2.3e-173 614.8 Lactobacillaceae sitA GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0042597,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K09818,ko:K11601,ko:K11604,ko:K19975,ko:K19976 ko02010,ko02020,map02010,map02020 M00243,M00316,M00317,M00792 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.1,3.A.1.15.15,3.A.1.15.7,3.A.1.15.9 iECED1_1282.ECED1_1296 Bacteria 1TRKU@1239,3F4B9@33958,4HAKT@91061,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family PGHMIELC_00447 220668.lp_1098 3.1e-50 204.1 Lactobacillaceae Bacteria 1VKHU@1239,2EK0P@1,33DR7@2,3F6X8@33958,4HP3S@91061 NA|NA|NA PGHMIELC_00448 220668.lp_1101 1.2e-166 592.4 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPSY@1239,3F3RM@33958,4HB0Z@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily. LDH family PGHMIELC_00449 220668.lp_1102 2.2e-260 904.4 Lactobacillaceae citP ko:K03319 ko00000 2.A.47 Bacteria 1TSGE@1239,3F4RH@33958,4HDE4@91061,COG0471@1,COG0471@2 NA|NA|NA P Sodium:sulfate symporter transmembrane region PGHMIELC_00450 220668.lp_1103 2.9e-179 634.4 Lactobacillaceae citR Bacteria 1TPUB@1239,3F4PP@33958,4HCAR@91061,COG2390@1,COG2390@2 NA|NA|NA K sugar-binding domain protein PGHMIELC_00451 220668.lp_1105 5.1e-207 726.9 Lactobacillaceae mez_1 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 R00214 RC00105 ko00000,ko00001,ko01000 Bacteria 1TPJ3@1239,3F4GN@33958,4H9WR@91061,COG0281@1,COG0281@2 NA|NA|NA C Malic enzyme, NAD binding domain PGHMIELC_00452 220668.lp_1106 4.8e-188 663.7 Lactobacillaceae citC 6.2.1.22 ko:K01910 ko02020,map02020 R04449 RC00012,RC00039 ko00000,ko00001,ko01000 Bacteria 1TSGQ@1239,3FB9D@33958,4HDAU@91061,COG3053@1,COG3053@2 NA|NA|NA H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase PGHMIELC_00453 220668.lp_1107 9e-44 182.6 Lactobacillaceae citD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008815,GO:0009346,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016833,GO:0032991,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 ko:K01646 ko02020,map02020 R00362 RC00067,RC01118 ko00000,ko00001 Bacteria 1VEZZ@1239,3F7FR@33958,4HNXD@91061,COG3052@1,COG3052@2 NA|NA|NA C Covalent carrier of the coenzyme of citrate lyase PGHMIELC_00454 220668.lp_1108 5.5e-164 583.6 Lactobacillaceae citE 4.1.3.25,4.1.3.34 ko:K01644,ko:K18292 ko00660,ko01100,ko02020,map00660,map01100,map02020 R00237,R00362 RC00067,RC00502,RC01118,RC01205 ko00000,ko00001,ko01000 Bacteria 1TPDY@1239,3F47Q@33958,4HD40@91061,COG2301@1,COG2301@2 NA|NA|NA G Belongs to the HpcH HpaI aldolase family PGHMIELC_00455 220668.lp_1109 4.6e-288 996.5 Lactobacillaceae citF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.8.3.10 ko:K01643 ko02020,map02020 R00362 RC00067,RC01118 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_0634 Bacteria 1TPN3@1239,3F4EA@33958,4HAE1@91061,COG3051@1,COG3051@2 NA|NA|NA H Citrate (pro-3S)-lyase alpha chain PGHMIELC_00457 220668.lp_1112 6.4e-257 892.9 Lactobacillaceae fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHPH@1239,3F3K0@33958,4HA6P@91061,COG0114@1,COG0114@2 NA|NA|NA C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate PGHMIELC_00458 220668.lp_1113 2.7e-263 914.1 Lactobacillaceae frdC 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAR@1239,3F3KJ@33958,4HAXN@91061,COG1053@1,COG1053@2 NA|NA|NA C FAD binding domain PGHMIELC_00459 220668.lp_1114 1.2e-94 352.4 Lactobacillaceae citX 2.4.2.52,2.7.7.61 ko:K05964,ko:K13927 ko02020,map02020 R09675,R10706 RC00049,RC00063 ko00000,ko00001,ko01000 Bacteria 1VB3E@1239,3F74S@33958,4HMZ5@91061,COG3697@1,COG3697@2 NA|NA|NA HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase PGHMIELC_00460 220668.lp_1115 1.6e-160 572.0 Lactobacillaceae mleR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 Bacteria 1TQ6Y@1239,3FC6N@33958,4HB94@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR family transcriptional regulator PGHMIELC_00461 220668.lp_1116 1.8e-167 595.1 Lactobacillaceae mleR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 Bacteria 1V5VW@1239,3F5D2@33958,4HHDY@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR family PGHMIELC_00462 220668.lp_1118 4.2e-308 1063.1 Lactobacillaceae sfcA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0030145,GO:0036094,GO:0043167,GO:0043169,GO:0043464,GO:0044237,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.1.1.38,4.1.1.101 ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 R00214,R11074 RC00105,RC00282 ko00000,ko00001,ko01000 Bacteria 1TPJ3@1239,3F3RH@33958,4HBF1@91061,COG0281@1,COG0281@2 NA|NA|NA C Malic enzyme PGHMIELC_00463 220668.lp_1119 1.4e-165 589.0 Lactobacillaceae mleP ko:K07088 ko00000 Bacteria 1UY4N@1239,3F3S0@33958,4HDX5@91061,COG0679@1,COG0679@2 NA|NA|NA S Sodium Bile acid symporter family PGHMIELC_00464 220668.lp_1120 5.8e-253 879.8 Lactobacillaceae yfnA ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3F3QY@33958,4HA66@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid PGHMIELC_00465 220668.lp_1121 3e-99 367.9 Lactobacillaceae Bacteria 1VB4T@1239,3F497@33958,4HMUC@91061,COG4684@1,COG4684@2 NA|NA|NA S ECF transporter, substrate-specific component PGHMIELC_00466 220668.lp_1123 2.2e-24 117.5 Lactobacillaceae Bacteria 1U69S@1239,29P8R@1,30A6V@2,3F7E0@33958,4IG0X@91061 NA|NA|NA PGHMIELC_00467 220668.lp_1124 0.0 1097.8 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TQYU@1239,3F4RM@33958,4HC4H@91061,COG1073@1,COG1073@2 NA|NA|NA S Alpha beta PGHMIELC_00468 220668.lp_1125 5.4e-275 953.0 Lactobacillaceae cydA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iPC815.YPO1117,iSBO_1134.SBO_2253,iSFxv_1172.SFxv_0621,iS_1188.S0577,iSbBS512_1146.SbBS512_E2337 Bacteria 1TRH4@1239,3F4MJ@33958,4HA19@91061,COG1271@1,COG1271@2 NA|NA|NA C ubiquinol oxidase PGHMIELC_00469 220668.lp_1126 2.6e-183 647.9 Lactobacillaceae cydB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,iYO844.BSU38750,ic_1306.c1120 Bacteria 1TRYV@1239,3F40S@33958,4H9KF@91061,COG1294@1,COG1294@2 NA|NA|NA C Cytochrome d ubiquinol oxidase subunit II PGHMIELC_00470 220668.lp_1128 0.0 1114.0 Lactobacillaceae cydD GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 3.A.1.129 Bacteria 1TQ1P@1239,3F451@33958,4HAN0@91061,COG4988@1,COG4988@2 NA|NA|NA CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD PGHMIELC_00471 220668.lp_1129 0.0 1157.1 Lactobacillaceae cydD ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 3.A.1.129 Bacteria 1UHN5@1239,3F4PG@33958,4HAAB@91061,COG4987@1,COG4987@2 NA|NA|NA CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC PGHMIELC_00472 60520.HR47_09980 1.5e-156 558.9 Lactobacillaceae ddpX 3.4.13.22 ko:K08641 ko01502,ko02020,map01502,map02020 M00651 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Bacteria 1V2TG@1239,3FBDS@33958,4IPPW@91061,COG3786@1,COG3786@2 NA|NA|NA S L,D-transpeptidase catalytic domain PGHMIELC_00473 220668.lp_1134 2.3e-182 644.8 Lactobacillaceae hepT 2.5.1.30,2.5.1.90 ko:K00805,ko:K02523 ko00900,ko01110,map00900,map01110 R09247,R09248 RC00279 ko00000,ko00001,ko01000,ko01006 Bacteria 1TR0U@1239,3F4GC@33958,4H9RH@91061,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family PGHMIELC_00474 220668.lp_1135 2.9e-165 587.8 Lactobacillaceae menA 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1TSZV@1239,3F3JM@33958,4HA68@91061,COG1575@1,COG1575@2 NA|NA|NA H 1,4-dihydroxy-2-naphthoate PGHMIELC_00475 220668.lp_1136 8.7e-184 649.4 Lactobacillaceae Bacteria 1TPT5@1239,3F4XH@33958,4HAPJ@91061,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold PGHMIELC_00476 220668.lp_1138 1.3e-111 409.1 Lactobacillaceae acmA 3.2.1.17 ko:K01185,ko:K02395 ko00000,ko01000,ko02035 Bacteria 1V7JY@1239,3F584@33958,4HIY4@91061,COG1705@1,COG1705@2 NA|NA|NA NU mannosyl-glycoprotein PGHMIELC_00477 220668.lp_1139 9.1e-104 382.9 Lactobacillaceae xpt GO:0003674,GO:0003824,GO:0006139,GO:0006166,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046128,GO:0046129,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816,ko:K09685 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko03000,ko04147 iYO844.BSU22070 Bacteria 1V1DU@1239,3F49S@33958,4HFNW@91061,COG0503@1,COG0503@2 NA|NA|NA F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis PGHMIELC_00478 220668.lp_1140 1e-93 349.4 Lactobacillaceae Bacteria 1V14J@1239,3F4SX@33958,4HCBK@91061,COG4843@1,COG4843@2 NA|NA|NA S UPF0316 protein PGHMIELC_00479 220668.lp_1141 1.3e-218 765.4 Lactobacillaceae purK2 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQCD@1239,3FC8U@33958,4HJI4@91061,COG0026@1,COG0026@2 NA|NA|NA F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate PGHMIELC_00480 220668.lp_1144 0.0 1468.8 Lactobacillaceae pcrA 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPSU@1239,3F400@33958,4HB12@91061,COG0210@1,COG0210@2 NA|NA|NA L ATP-dependent DNA helicase PGHMIELC_00481 220668.lp_1145 0.0 1300.8 Lactobacillaceae ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1TPQ3@1239,3F43C@33958,4HA1D@91061,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA PGHMIELC_00482 220668.lp_1146 2.6e-198 698.0 Lactobacillaceae camS Bacteria 1TSYE@1239,3F3KI@33958,4HBI8@91061,COG4851@1,COG4851@2 NA|NA|NA S sex pheromone PGHMIELC_00483 220668.lp_1147 3.2e-50 204.1 Lactobacillaceae gatC 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 iAF987.Gmet_0076 Bacteria 1VEK3@1239,3F7XB@33958,4HNNA@91061,COG0721@1,COG0721@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) PGHMIELC_00484 220668.lp_1148 2.5e-275 954.1 Lactobacillaceae gatA 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 1TP0C@1239,3F4BK@33958,4HBAZ@91061,COG0154@1,COG0154@2 NA|NA|NA J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) PGHMIELC_00485 220668.lp_1149 7.7e-274 949.1 Lactobacillaceae gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 ko:K01876,ko:K02434 ko00970,ko01100,map00970,map01100 M00359,M00360 R03905,R04212,R05577 RC00010,RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPG3@1239,3F44H@33958,4HAFB@91061,COG0064@1,COG0064@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) PGHMIELC_00486 220668.lp_1150 1e-190 672.5 Lactobacillaceae yegS GO:0001727,GO:0003674,GO:0003824,GO:0004143,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0030258,GO:0044237,GO:0044238,GO:0044255,GO:0046834,GO:0071704 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 R02240 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TQAU@1239,3F447@33958,4H9WD@91061,COG1597@1,COG1597@2 NA|NA|NA G Lipid kinase PGHMIELC_00487 220668.lp_1151 4e-259 900.2 Lactobacillaceae rumA GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 ko00000,ko01000,ko03009 Bacteria 1TP4H@1239,3F41R@33958,4HA6M@91061,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family PGHMIELC_00488 220668.lp_1153 2.1e-100 371.7 Lactobacillaceae yobS GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 Bacteria 1V1DM@1239,3F5CS@33958,4HG0Y@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family PGHMIELC_00489 220668.lp_1154 0.0 1466.1 Lactobacillaceae yfgQ ko:K12952 ko00000,ko01000 3.A.3.23 Bacteria 1TPF5@1239,3F4Y1@33958,4H9ZI@91061,COG0474@1,COG0474@2 NA|NA|NA P E1-E2 ATPase PGHMIELC_00490 220668.lp_1155 4e-240 837.0 Lactobacillaceae pts13C ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 Bacteria 1V5SI@1239,3F3Z5@33958,4HJTK@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane PGHMIELC_00491 220668.lp_1156 6.1e-168 596.7 Lactobacillaceae Bacteria 1V8NG@1239,3F41V@33958,4HJ22@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF915) PGHMIELC_00492 220668.lp_1157 1.9e-150 538.5 Lactobacillaceae gntR Bacteria 1TR0N@1239,3F42G@33958,4HB9E@91061,COG1737@1,COG1737@2 NA|NA|NA K rpiR family PGHMIELC_00493 220668.lp_1158 1.2e-143 515.8 Lactobacillaceae lys ko:K07273 ko00000 Bacteria 1V484@1239,3F4K0@33958,4HQWA@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 PGHMIELC_00494 220668.lp_1159 1.1e-62 245.7 Lactobacillaceae Bacteria 1VNS7@1239,2EGZM@1,33ARR@2,3F83W@33958,4HSZW@91061 NA|NA|NA S Domain of unknown function (DUF4828) PGHMIELC_00495 1136177.KCA1_0934 2.7e-31 140.6 Lactobacillaceae cspA ko:K03704 ko00000,ko03000 Bacteria 1VEE0@1239,3F7VH@33958,4IG8P@91061,COG1278@1,COG1278@2 NA|NA|NA K 'Cold-shock' DNA-binding domain PGHMIELC_00496 220668.lp_1161 5.4e-189 666.8 Lactobacillaceae mocA ko:K22230 ko00562,ko01120,map00562,map01120 R09954 RC00182 ko00000,ko00001,ko01000 Bacteria 1TQSS@1239,3F4EV@33958,4HCIG@91061,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase PGHMIELC_00497 220668.lp_1162 2.6e-239 834.3 Lactobacillaceae yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TQ9R@1239,3F4K8@33958,4HANR@91061,COG0513@1,COG0513@2 NA|NA|NA L DEAD DEAH box helicase PGHMIELC_00499 220668.lp_1163 2.3e-75 288.1 Lactobacillaceae ko:K06149 ko00000 Bacteria 1UG0Z@1239,3F5E2@33958,4IF22@91061,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein family PGHMIELC_00500 220668.lp_1164 1e-243 849.0 Lactobacillaceae pts14C ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 Bacteria 1TP8D@1239,3FC6Y@33958,4HE28@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane PGHMIELC_00501 220668.lp_1165 6.8e-164 583.2 Lactobacillaceae Bacteria 1V8NG@1239,3F41V@33958,4HJ22@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF915) PGHMIELC_00503 220668.lp_1166 1.3e-73 282.3 Lactobacillaceae Bacteria 1U5GY@1239,29NS2@1,309Q2@2,3F5XC@33958,4IF7R@91061 NA|NA|NA PGHMIELC_00504 220668.lp_1168 5e-107 393.7 Lactobacillaceae Bacteria 1UG8R@1239,2BPPE@1,32IGN@2,3F5MF@33958,4IF4N@91061 NA|NA|NA PGHMIELC_00505 220668.lp_1169 7.6e-255 885.9 Lactobacillaceae gdhA 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 R00248 RC00006,RC02799 ko00000,ko00001,ko01000 Bacteria 1TP45@1239,3F4DS@33958,4HAEI@91061,COG0334@1,COG0334@2 NA|NA|NA E Belongs to the Glu Leu Phe Val dehydrogenases family PGHMIELC_00506 220668.lp_1171 5.3e-220 770.0 Lactobacillaceae pbpX1 Bacteria 1V4BS@1239,3F3QN@33958,4HJRT@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase PGHMIELC_00507 220668.lp_1173 6.8e-209 733.0 Lactobacillaceae mnaA 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1TQZT@1239,3F3KQ@33958,4HBI3@91061,COG0381@1,COG0381@2 NA|NA|NA G Belongs to the UDP-N-acetylglucosamine 2-epimerase family PGHMIELC_00508 220668.lp_1174 3.3e-156 557.8 Lactobacillaceae yihY ko:K07058 ko00000 Bacteria 1U7HM@1239,3F4TC@33958,4H9MJ@91061,COG1295@1,COG1295@2 NA|NA|NA S Belongs to the UPF0761 family PGHMIELC_00509 220668.lp_1175 9.7e-132 476.1 Lactobacillaceae glpF ko:K02440 ko00000,ko02000 1.A.8.1,1.A.8.2 Bacteria 1TP4T@1239,3F42H@33958,4HAWP@91061,COG0580@1,COG0580@2 NA|NA|NA U Belongs to the MIP aquaporin (TC 1.A.8) family PGHMIELC_00510 220668.lp_1176 7.6e-216 756.1 Lactobacillaceae glf GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 iNJ661.Rv3809c Bacteria 1TQB9@1239,3F52G@33958,4HB5F@91061,COG0562@1,COG0562@2 NA|NA|NA M UDP-galactopyranose mutase PGHMIELC_00511 1136177.KCA1_0959 5.4e-17 94.7 Lactobacillaceae wcoI 2.7.10.1,2.7.10.2 ko:K08252,ko:K08253 ko00000,ko01000 Bacteria 1U7G1@1239,3F9KE@33958,4IHC3@91061,COG3944@1,COG3944@2 NA|NA|NA M biosynthesis protein PGHMIELC_00512 1423724.BAMM01000007_gene953 1.5e-08 66.6 Lactobacillaceae ywqD 2.7.10.1 ko:K08252,ko:K16554 ko05111,map05111 ko00000,ko00001,ko01000,ko02000 8.A.3.1 Bacteria 1TS4R@1239,3F4BM@33958,4HCEN@91061,COG0489@1,COG0489@2 NA|NA|NA D Capsular exopolysaccharide family PGHMIELC_00513 1423780.LOT_1618 3e-10 73.2 Lactobacillaceae pbpX2 ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1V0GX@1239,3F4TH@33958,4HCXH@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase PGHMIELC_00514 701521.PECL_1255 1.4e-24 120.9 Lactobacillaceae Bacteria 1VVEA@1239,2EA07@1,3345N@2,3F82F@33958,4HW16@91061 NA|NA|NA PGHMIELC_00515 1136177.KCA1_1004 3.5e-79 301.6 Lactobacillaceae cps1D Bacteria 1U6EG@1239,3F539@33958,4HG4F@91061,COG1442@1,COG1442@2 NA|NA|NA M Domain of unknown function (DUF4422) PGHMIELC_00516 1221537.B807_196 1.4e-94 353.2 Lactobacillaceae waaB GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008378,GO:0008610,GO:0008653,GO:0008921,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035250,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 ko:K02840 ko00540,ko01100,map00540,map01100 M00080 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT4 Bacteria 1UHSF@1239,3F428@33958,4HB04@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 PGHMIELC_00517 1414720.CBYM010000031_gene2025 5.6e-54 218.4 Clostridiaceae tagB 2.7.8.12 ko:K09809 ko00000,ko01000 Bacteria 1TP75@1239,24ED0@186801,36FYJ@31979,COG1887@1,COG1887@2 NA|NA|NA M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase PGHMIELC_00518 913848.AELK01000019_gene800 7.9e-59 234.2 Lactobacillaceae 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 Bacteria 1V4NS@1239,3F6P7@33958,4HHDW@91061,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 PGHMIELC_00519 60520.HR47_01135 2.6e-173 615.1 Lactobacillaceae rfbX Bacteria 1TP7R@1239,3F48Q@33958,4HC84@91061,COG2244@1,COG2244@2 NA|NA|NA S Membrane protein involved in the export of O-antigen and teichoic acid PGHMIELC_00520 797515.HMPREF9103_01103 2.4e-63 248.1 Lactobacillaceae tagD 2.7.7.15,2.7.7.39 ko:K00968,ko:K00980 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 M00090 R00856,R01890,R02590 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3KY@1239,3F65R@33958,4HGWZ@91061,COG0615@1,COG0615@2 NA|NA|NA IM Glycerol-3-phosphate cytidylyltransferase PGHMIELC_00521 1136177.KCA1_0962 1.5e-100 373.2 Lactobacillaceae Bacteria 1V2HD@1239,3F493@33958,4IEUG@91061,COG5434@1,COG5434@2 NA|NA|NA M Parallel beta-helix repeats PGHMIELC_00522 1136177.KCA1_0980 8.5e-182 642.9 Lactobacillaceae rfbB GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPWM@1239,3F3R6@33958,4HA3Y@91061,COG1088@1,COG1088@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily PGHMIELC_00523 1136177.KCA1_0981 3.3e-101 374.4 Lactobacillaceae ko:K04763 ko00000,ko03036 Bacteria 1V2RX@1239,3F4SP@33958,4IEJ7@91061,COG0582@1,COG0582@2 NA|NA|NA L Integrase PGHMIELC_00524 1136177.KCA1_0982 5.7e-130 470.3 Lactobacillaceae epsB Bacteria 1UZCR@1239,3F4M5@33958,4HE26@91061,COG3944@1,COG3944@2 NA|NA|NA M biosynthesis protein PGHMIELC_00525 1136177.KCA1_0983 7.3e-127 459.9 Lactobacillaceae ywqD 2.7.10.1 ko:K08252,ko:K16554 ko05111,map05111 ko00000,ko00001,ko01000,ko02000 8.A.3.1 Bacteria 1TS4R@1239,3F4BM@33958,4HCEN@91061,COG0489@1,COG0489@2 NA|NA|NA D Capsular exopolysaccharide family PGHMIELC_00526 1136177.KCA1_0984 2e-143 515.0 Lactobacillaceae ywqE 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1TQ1T@1239,3F3RT@33958,4HDZR@91061,COG4464@1,COG4464@2 NA|NA|NA GM PHP domain protein PGHMIELC_00527 1136177.KCA1_0985 3.8e-176 624.0 Lactobacillaceae cps2D 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS00780 Bacteria 1V34Y@1239,3F5GY@33958,4HCJE@91061,COG0451@1,COG0451@2 NA|NA|NA M RmlD substrate binding domain PGHMIELC_00528 1136177.KCA1_0986 2.4e-124 451.4 Lactobacillaceae tuaA Bacteria 1TP7M@1239,3F5WM@33958,4HB15@91061,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase PGHMIELC_00529 1291743.LOSG293_120090 1.3e-132 479.6 Lactobacillaceae cps4F GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.306 ko:K12583,ko:K21365 ko00000,ko01000,ko01003,ko01005 GT4 Bacteria 1UHSF@1239,3F428@33958,4HB04@91061,COG0438@1,COG0438@2,COG0707@1,COG0707@2 NA|NA|NA M Glycosyl transferases group 1 PGHMIELC_00530 1291743.LOSG293_120100 8.7e-126 456.8 Lactobacillaceae cps4G Bacteria 1V369@1239,3F64A@33958,4HI0I@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 PGHMIELC_00531 220668.lp_2101 1.2e-172 612.8 Lactobacillaceae Bacteria 1U7PF@1239,2AHJR@1,317XH@2,3F9ZB@33958,4IHKS@91061 NA|NA|NA PGHMIELC_00532 1136177.KCA1_1778 5.8e-132 477.2 Lactobacillaceae cps4I Bacteria 1UZYU@1239,3F6ND@33958,4HQ2D@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 PGHMIELC_00533 562743.JH976435_gene3049 9.9e-48 197.6 Bacilli epsI ko:K19426 ko00000,ko01000 Bacteria 1V5MK@1239,4HJ1D@91061,COG5039@1,COG5039@2 NA|NA|NA GM Exopolysaccharide biosynthesis protein PGHMIELC_00534 189426.PODO_24660 3.2e-83 315.8 Bacilli cps2J Bacteria 1TR7A@1239,4HEKF@91061,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein PGHMIELC_00535 1136177.KCA1_0995 1.3e-20 105.1 Bacteria relB ko:K07473 ko00000,ko02048 Bacteria COG3077@1,COG3077@2 NA|NA|NA L bacterial-type proximal promoter sequence-specific DNA binding PGHMIELC_00536 1136177.KCA1_0395 2.2e-26 124.8 Lactobacillaceae Bacteria 1UV28@1239,3F7MP@33958,4HWU5@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein PGHMIELC_00537 1136177.KCA1_0395 2.5e-83 315.5 Lactobacillaceae Bacteria 1UV28@1239,3F7MP@33958,4HWU5@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein PGHMIELC_00538 1136177.KCA1_0395 1.9e-19 102.1 Lactobacillaceae Bacteria 1UV28@1239,3F7MP@33958,4HWU5@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein PGHMIELC_00539 1136177.KCA1_0396 1.6e-75 290.4 Bacteria ko:K21493 ko00000,ko01000,ko02048 Bacteria COG3209@1,COG3209@2 NA|NA|NA M self proteolysis PGHMIELC_00540 1136177.KCA1_0397 2.4e-43 181.0 Bacilli Bacteria 1VGIR@1239,2EARU@1,334TY@2,4I0ZC@91061 NA|NA|NA PGHMIELC_00542 220668.lp_0379 2.1e-120 438.7 Lactobacillaceae Bacteria 1UUT4@1239,2BF1Z@1,328TX@2,3F9UD@33958,4IHH1@91061 NA|NA|NA PGHMIELC_00543 1136177.KCA1_0401 1.4e-35 155.2 Lactobacillaceae Bacteria 1U84J@1239,29QHX@1,30BHD@2,3FAIP@33958,4II20@91061 NA|NA|NA PGHMIELC_00544 220668.lp_0377 1.1e-30 139.0 Lactobacillaceae Bacteria 1U7SF@1239,29QHX@1,30B9Q@2,3FA3Y@33958,4IHPT@91061 NA|NA|NA PGHMIELC_00545 220668.lp_0379 1.2e-134 486.1 Lactobacillaceae Bacteria 1UUT4@1239,2BF1Z@1,328TX@2,3F9UD@33958,4IHH1@91061 NA|NA|NA PGHMIELC_00546 220668.lp_0379 4.4e-112 411.0 Lactobacillaceae Bacteria 1UUT4@1239,2BF1Z@1,328TX@2,3F9UD@33958,4IHH1@91061 NA|NA|NA PGHMIELC_00547 1158609.I586_02995 1e-10 72.4 Bacilli ko:K11044 ko00000,ko01000,ko02042 Bacteria 1V069@1239,4HD0D@91061,COG5585@1,COG5585@2 NA|NA|NA PGHMIELC_00548 1136177.KCA1_0435 5e-151 540.4 Lactobacillaceae Bacteria 1TRSF@1239,3F3YG@33958,4HADR@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family PGHMIELC_00549 1158609.I586_02996 1.5e-15 89.4 Bacilli Bacteria 1W197@1239,2FBRA@1,343W4@2,4HY0S@91061 NA|NA|NA PGHMIELC_00550 220668.lp_0379 2.6e-85 321.6 Lactobacillaceae Bacteria 1UUT4@1239,2BF1Z@1,328TX@2,3F9UD@33958,4IHH1@91061 NA|NA|NA PGHMIELC_00551 220668.lp_0388 5.5e-55 220.3 Firmicutes Bacteria 1VQHD@1239,2E8X6@1,33378@2 NA|NA|NA S Immunity protein 63 PGHMIELC_00552 1158609.I586_02668 7.2e-28 130.2 Enterococcaceae Bacteria 1U39B@1239,2BUT9@1,32Q4Q@2,4B5E3@81852,4IAD9@91061 NA|NA|NA S Barstar (barnase inhibitor) PGHMIELC_00553 1136177.KCA1_0996 3.9e-170 604.0 Lactobacillaceae cps3A ko:K07011 ko00000 Bacteria 1V2KI@1239,3FBEH@33958,4IPXM@91061,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 PGHMIELC_00554 1136177.KCA1_0997 3.7e-176 624.0 Lactobacillaceae cps3B ko:K07011 ko00000 Bacteria 1V4NS@1239,3F6P7@33958,4HHDW@91061,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 PGHMIELC_00555 220668.lp_1219 4.2e-222 776.9 Lactobacillaceae glf GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 iNJ661.Rv3809c Bacteria 1TQB9@1239,3F52G@33958,4HB5F@91061,COG0562@1,COG0562@2 NA|NA|NA M UDP-galactopyranose mutase PGHMIELC_00556 220668.lp_1220 1.4e-203 715.3 Lactobacillaceae cps3D Bacteria 1U796@1239,29PZP@1,30AY4@2,3F956@33958,4IH42@91061 NA|NA|NA PGHMIELC_00557 220668.lp_1221 4.8e-111 407.1 Lactobacillaceae cps3E Bacteria 1U7AC@1239,29Q0I@1,30AZ0@2,3F979@33958,4IH5A@91061 NA|NA|NA PGHMIELC_00558 1136177.KCA1_1001 2.7e-163 581.6 Lactobacillaceae cps3F Bacteria 1VDRM@1239,2DN9M@1,32W9S@2,3F6CA@33958,4HRQ0@91061 NA|NA|NA PGHMIELC_00559 220668.lp_1225 1.3e-207 728.8 Lactobacillaceae cps3H Bacteria 1U7CU@1239,29Q29@1,30B0V@2,3F9DU@33958,4IH8D@91061 NA|NA|NA PGHMIELC_00560 220668.lp_1226 4.9e-204 716.8 Lactobacillaceae cps3I Bacteria 1V858@1239,3F6SS@33958,4HJH5@91061,COG3594@1,COG3594@2 NA|NA|NA G Acyltransferase family PGHMIELC_00561 220668.lp_1227 4e-147 527.3 Lactobacillaceae cps1D Bacteria 1U6EG@1239,3F539@33958,4HG4F@91061,COG1442@1,COG1442@2 NA|NA|NA M Domain of unknown function (DUF4422) PGHMIELC_00562 220668.lp_1228 4.7e-137 493.8 Lactobacillaceae ko:K07506 ko00000,ko03000 Bacteria 1UIXD@1239,3FBTP@33958,4ISVP@91061,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein PGHMIELC_00563 220668.lp_1229 0.0 1203.0 Lactobacillaceae Bacteria 1VXP5@1239,3F5AT@33958,4HWZF@91061,COG3203@1,COG3203@2,COG4932@1,COG4932@2 NA|NA|NA M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane PGHMIELC_00564 220668.lp_1230 9.6e-74 282.7 Lactobacillaceae Bacteria 1U65M@1239,3F74C@33958,4IFVG@91061,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein PGHMIELC_00565 220668.lp_1231 1.1e-259 902.1 Lactobacillaceae rfbX Bacteria 1TP7R@1239,3F48Q@33958,4HC84@91061,COG2244@1,COG2244@2 NA|NA|NA S Membrane protein involved in the export of O-antigen and teichoic acid PGHMIELC_00566 220668.lp_1233 3.2e-121 441.0 Lactobacillaceae rfbP Bacteria 1TP7M@1239,3F51J@33958,4HCBG@91061,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase PGHMIELC_00567 220668.lp_1234 3.8e-53 213.8 Lactobacillaceae Bacteria 1U5XG@1239,2CB5C@1,309Y8@2,3F6NB@33958,4IFKU@91061 NA|NA|NA PGHMIELC_00568 220668.lp_1235 7.3e-33 146.0 Firmicutes Bacteria 1VKCM@1239,2DR42@1,33A2M@2 NA|NA|NA S Protein of unknown function (DUF2922) PGHMIELC_00569 220668.lp_1236 7e-30 136.0 Lactobacillaceae Bacteria 1U6DC@1239,2CB5D@1,30A9Q@2,3F7ND@33958,4IG53@91061 NA|NA|NA PGHMIELC_00570 220668.lp_1237 6.2e-25 119.4 Lactobacillaceae Bacteria 1U8HB@1239,29QQX@1,30BQQ@2,3FAZG@33958,4IIF6@91061 NA|NA|NA PGHMIELC_00571 220668.lp_1238 1.5e-100 372.1 Bacteria Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation PGHMIELC_00572 220668.lp_1239 1.1e-124 452.6 Lactobacillaceae Bacteria 1U5KM@1239,2DKK6@1,309S9@2,3F65N@33958,4IFBJ@91061 NA|NA|NA PGHMIELC_00573 220668.lp_1240 2.2e-140 505.0 Lactobacillaceae recX GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496 2.4.1.337 ko:K03565,ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003,ko03400 GT4 Bacteria 1V72V@1239,3F4BY@33958,4HJ7R@91061,COG2137@1,COG2137@2 NA|NA|NA S Regulatory protein RecX PGHMIELC_00574 220668.lp_1241 4.1e-106 390.6 Lactobacillaceae ygaC ko:K07586 ko00000 Bacteria 1TRX8@1239,3F48S@33958,4H9NM@91061,COG3557@1,COG3557@2 NA|NA|NA J Belongs to the UPF0374 family PGHMIELC_00575 220668.lp_1242 1.5e-133 482.3 Lactobacillaceae cwlO ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1V9ZW@1239,3F5SU@33958,4HH84@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family PGHMIELC_00576 1400520.LFAB_05505 7.8e-48 196.4 Bacteria Bacteria COG1396@1,COG1396@2 NA|NA|NA K sequence-specific DNA binding PGHMIELC_00577 220668.lp_1244 1.3e-27 128.3 Lactobacillaceae Bacteria 1U6EJ@1239,29FID@1,302G1@2,3F7QP@33958,4IG6A@91061 NA|NA|NA S Antitoxin component of a toxin-antitoxin (TA) module PGHMIELC_00578 1136177.KCA1_1020 4.2e-145 522.3 Lactobacillaceae pbpX Bacteria 1V4BS@1239,3F3QN@33958,4HJRT@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase PGHMIELC_00579 220668.lp_1245 1.3e-168 599.0 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1UXY2@1239,3F4M2@33958,4HD1S@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily PGHMIELC_00580 220668.lp_1247 9.3e-188 662.9 Lactobacillaceae yueF GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 Bacteria 1TQ84@1239,3F418@33958,4H9SR@91061,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter PGHMIELC_00581 220668.lp_1248 3.7e-72 277.3 Lactobacillaceae tagD 2.7.7.15,2.7.7.39 ko:K00968,ko:K00980 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 M00090 R00856,R01890,R02590 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3KY@1239,3F65R@33958,4HGWZ@91061,COG0615@1,COG0615@2 NA|NA|NA IM Glycerol-3-phosphate cytidylyltransferase PGHMIELC_00582 220668.lp_1249 9.5e-213 746.1 Lactobacillaceae gntP ko:K03299,ko:K06155 ko00000,ko02000 2.A.8,2.A.8.1.4 Bacteria 1TQ14@1239,3F3V0@33958,4HB0Y@91061,COG2610@1,COG2610@2 NA|NA|NA EG Gluconate PGHMIELC_00583 220668.lp_1250 6.7e-292 1009.2 Lactobacillaceae gntK 2.7.1.12,2.7.1.16,2.7.1.17,2.7.1.5 ko:K00848,ko:K00851,ko:K00853,ko:K00854 ko00030,ko00040,ko00051,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map00051,map01100,map01110,map01120,map01130,map01200 M00014 R01526,R01639,R01737,R01902,R02439,R03014 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ1I@1239,3F4R2@33958,4H9W6@91061,COG1070@1,COG1070@2 NA|NA|NA G Belongs to the FGGY kinase family PGHMIELC_00584 220668.lp_1251 1.7e-170 605.1 Lactobacillaceae gnd 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHN4@1239,3F4X7@33958,4IS44@91061,COG1023@1,COG1023@2 NA|NA|NA G Dehydrogenase PGHMIELC_00585 220668.lp_1253 9.8e-255 885.6 Lactobacillaceae gor 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1TS0Z@1239,3F3K2@33958,4HBYB@91061,COG1249@1,COG1249@2 NA|NA|NA C Glutathione reductase PGHMIELC_00586 220668.lp_1255 6.9e-308 1062.4 Lactobacillaceae prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02837,ko:K07133 ko00000,ko03012 Bacteria 1TPYT@1239,3F489@33958,4HADS@91061,COG4108@1,COG4108@2 NA|NA|NA J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP PGHMIELC_00587 220668.lp_1256 4.8e-279 966.5 Lactobacillaceae Bacteria 1W0CD@1239,2FCGI@1,344JZ@2,3FB90@33958,4HYAJ@91061 NA|NA|NA PGHMIELC_00588 220668.lp_1257 6.5e-198 696.4 Lactobacillaceae Bacteria 1UHY3@1239,3FBRZ@33958,4ISAI@91061,COG4932@1,COG4932@2 NA|NA|NA M MucBP domain PGHMIELC_00589 220668.lp_1258 7.1e-161 573.2 Lactobacillaceae lysR5 Bacteria 1UXFR@1239,3F4XG@33958,4HBNZ@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain PGHMIELC_00590 60520.HR47_01000 5.5e-126 457.2 Lactobacillaceae yxaA ko:K07090 ko00000 Bacteria 1TPMA@1239,3F3T9@33958,4HESP@91061,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein PGHMIELC_00591 220668.lp_1260 3.2e-57 227.6 Lactobacillaceae ywjH Bacteria 1VAPQ@1239,3FBP6@33958,4IRG9@91061,COG4272@1,COG4272@2 NA|NA|NA S Protein of unknown function (DUF1634) PGHMIELC_00592 220668.lp_1261 1.3e-309 1068.1 Lactobacillaceae oppA ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F3JE@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substratebinding protein PGHMIELC_00593 220668.lp_1262 2.3e-165 588.2 Lactobacillaceae oppB ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP1S@1239,3F42T@33958,4HA2S@91061,COG0601@1,COG0601@2 NA|NA|NA P ABC-type dipeptide oligopeptide nickel transport systems, permease components PGHMIELC_00594 220668.lp_1263 1.1e-189 669.1 Lactobacillaceae oppC ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP4R@1239,3F3W3@33958,4H9PZ@91061,COG1173@1,COG1173@2 NA|NA|NA EP ABC-type dipeptide oligopeptide nickel transport systems, permease components PGHMIELC_00595 220668.lp_1264 9.2e-203 712.6 Lactobacillaceae oppD ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP6E@1239,3F41T@33958,4HA4E@91061,COG0444@1,COG0444@2 NA|NA|NA P Belongs to the ABC transporter superfamily PGHMIELC_00596 220668.lp_1265 1.8e-181 641.7 Lactobacillaceae oppF ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1V36J@1239,3F4GM@33958,4H9YB@91061,COG4608@1,COG4608@2 NA|NA|NA P Belongs to the ABC transporter superfamily PGHMIELC_00597 220668.lp_1267 1e-63 249.2 Lactobacillaceae Bacteria 1U5ZS@1239,3F6RV@33958,4IFNS@91061,COG1846@1,COG1846@2 NA|NA|NA K Winged helix DNA-binding domain PGHMIELC_00598 220668.lp_1268 1.6e-102 378.6 Lactobacillaceae ko:K04763 ko00000,ko03036 Bacteria 1V2RX@1239,3F4SP@33958,4IEJ7@91061,COG0582@1,COG0582@2 NA|NA|NA L Integrase PGHMIELC_00599 220668.lp_1269 0.0 1273.5 Lactobacillaceae clpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03697 ko00000,ko03110 Bacteria 1TPMU@1239,3F3K9@33958,4HA0V@91061,COG0542@1,COG0542@2 NA|NA|NA O Belongs to the ClpA ClpB family PGHMIELC_00600 60520.HR47_00950 6.5e-30 136.0 Lactobacillaceae Bacteria 1U4CC@1239,2EI19@1,33BSS@2,3F8QK@33958,4IGST@91061 NA|NA|NA PGHMIELC_00601 1136177.KCA1_1042 2.7e-39 167.5 Lactobacillaceae ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 ko:K11189 ko00000,ko02000 4.A.2.1 Bacteria 1VA0R@1239,3F6XQ@33958,4HKGA@91061,COG1925@1,COG1925@2 NA|NA|NA G phosphocarrier protein HPR PGHMIELC_00602 220668.lp_1274 0.0 1107.4 Lactobacillaceae ptsI GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0008965,GO:0009401,GO:0016740,GO:0016772,GO:0016775,GO:0019197,GO:0032991,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 8.A.7 iB21_1397.B21_02277,iE2348C_1286.E2348C_2602,iEC042_1314.EC042_2625,iECBD_1354.ECBD_1265,iECB_1328.ECB_02316,iECD_1391.ECD_02316,iECH74115_1262.ECH74115_3647,iECIAI1_1343.ECIAI1_2474,iECIAI39_1322.ECIAI39_2562,iECO103_1326.ECO103_2935,iECO111_1330.ECO111_3146,iECO26_1355.ECO26_3469,iECP_1309.ECP_2440,iECSE_1348.ECSE_2707,iECSP_1301.ECSP_3364,iECUMN_1333.ECUMN_2738,iECW_1372.ECW_m2645,iECs_1301.ECs3288,iEKO11_1354.EKO11_1312,iEcE24377_1341.EcE24377A_2703,iEcHS_1320.EcHS_A2551,iEcSMS35_1347.EcSMS35_2571,iEcolC_1368.EcolC_1262,iLF82_1304.LF82_1770,iNRG857_1313.NRG857_12115,iSBO_1134.SBO_2440,iSDY_1059.SDY_2613,iSFV_1184.SFV_2468,iSF_1195.SF2471,iSFxv_1172.SFxv_2720,iSSON_1240.SSON_2505,iS_1188.S2617,iUMNK88_1353.UMNK88_3018,iWFL_1372.ECW_m2645,iZ_1308.Z3682 Bacteria 1TPK8@1239,3F3MS@33958,4H9VD@91061,COG1080@1,COG1080@2 NA|NA|NA G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) PGHMIELC_00603 220668.lp_1275 1.4e-223 781.9 Lactobacillaceae mgs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 GT4 Bacteria 1TPTA@1239,3F4H5@33958,4HA41@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase, group 1 family protein PGHMIELC_00604 220668.lp_1276 6.9e-200 703.0 Lactobacillaceae cpoA GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901576 ko:K13678 R10865 RC00005,RC00049 ko00000,ko01000,ko01003 GT4 Bacteria 1TPSS@1239,3F47X@33958,4HB9F@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase, group 1 family protein PGHMIELC_00605 220668.lp_1277 7.4e-189 666.4 Lactobacillaceae mprF ko:K07027 ko00000,ko02000 4.D.2 Bacteria 1UY7Z@1239,3F3UR@33958,4HCG6@91061,COG0392@1,COG0392@2 NA|NA|NA I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms PGHMIELC_00606 220668.lp_1278 1.9e-228 798.1 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1UFQ0@1239,3F4NV@33958,4IEW0@91061,COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family PGHMIELC_00607 220668.lp_1280 1.8e-228 798.1 Lactobacillaceae patA 2.6.1.1 ko:K00812,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00525 R00355,R00694,R00734,R00896,R02433,R02619,R04467,R05052 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase PGHMIELC_00608 220668.lp_1281 1.1e-34 152.1 Lactobacillaceae ykuJ Bacteria 1VKD0@1239,3F82V@33958,4HRGC@91061,COG4703@1,COG4703@2 NA|NA|NA S Protein of unknown function (DUF1797) PGHMIELC_00609 220668.lp_1283 0.0 1352.8 Lactobacillaceae ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 R05081,R10849 RC00017 ko00000,ko00001,ko01000 Bacteria 1TRMA@1239,3F3R7@33958,4H9S0@91061,COG1368@1,COG1368@2 NA|NA|NA M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily PGHMIELC_00615 1423724.BAMM01000028_gene2013 5.1e-08 62.0 Bacilli Bacteria 1VNIF@1239,2DS9J@1,33F5B@2,4HRE9@91061 NA|NA|NA PGHMIELC_00621 220668.lp_1289 2.8e-91 341.3 Lactobacillaceae apt 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816,ko:K09685 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko03000,ko04147 Bacteria 1V1XS@1239,3F6EK@33958,4HG1T@91061,COG0503@1,COG0503@2 NA|NA|NA F Phosphoribosyl transferase domain PGHMIELC_00622 220668.lp_1290 2e-181 641.7 Lactobacillaceae ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 1UY33@1239,3F41X@33958,4HDN5@91061,COG0659@1,COG0659@2 NA|NA|NA P secondary active sulfate transmembrane transporter activity PGHMIELC_00623 220668.lp_1291 1.4e-95 355.5 Lactobacillaceae Bacteria 1U5R9@1239,2CCDY@1,309UQ@2,3F6CU@33958,4IFFA@91061 NA|NA|NA PGHMIELC_00624 220668.lp_1292 2e-94 351.7 Lactobacillaceae Bacteria 1V8P4@1239,3F65X@33958,4HVM8@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain PGHMIELC_00625 220668.lp_1293 2.9e-156 557.8 Lactobacillaceae Bacteria 1UZK9@1239,3F5JR@33958,4HG1F@91061,COG0639@1,COG0639@2 NA|NA|NA T Calcineurin-like phosphoesterase superfamily domain PGHMIELC_00627 220668.lp_1295 1.3e-230 805.4 Lactobacillaceae mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 1TPT1@1239,3F49Y@33958,4HAEA@91061,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system PGHMIELC_00628 220668.lp_1296 4.4e-188 663.7 Lactobacillaceae hemH GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPKF@1239,3F4VU@33958,4HAYG@91061,COG0276@1,COG0276@2 NA|NA|NA H Catalyzes the ferrous insertion into protoporphyrin IX PGHMIELC_00629 220668.lp_1297 6.6e-254 882.9 Lactobacillaceae mmuP GO:0000096,GO:0000097,GO:0000100,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0015806,GO:0016020,GO:0016053,GO:0019752,GO:0022857,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682 ko:K02205,ko:K03293,ko:K11733,ko:K16235,ko:K16236 ko00000,ko02000 2.A.3.1,2.A.3.1.10,2.A.3.1.2 Bacteria 1UHNR@1239,3F4BG@33958,4HUT7@91061,COG0833@1,COG0833@2 NA|NA|NA E amino acid PGHMIELC_00630 220668.lp_1298 4.9e-168 597.0 Lactobacillaceae mmuM GO:0003674,GO:0003824,GO:0005488,GO:0006575,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008270,GO:0008757,GO:0008898,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033477,GO:0033554,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:1901564 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHQ5@1239,3F4UT@33958,4HAS6@91061,COG2040@1,COG2040@2 NA|NA|NA H homocysteine S-methyltransferase PGHMIELC_00631 220668.lp_1299 1.5e-291 1008.1 Lactobacillaceae tagE1 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1V09I@1239,3FBEI@33958,4IPXN@91061,COG0438@1,COG0438@2,COG2849@1,COG2849@2 NA|NA|NA M Glycosyl transferases group 1 PGHMIELC_00632 220668.lp_1300 3.1e-122 444.5 Lactobacillaceae Bacteria 1U53R@1239,2DKHQ@1,309HG@2,3F4DM@33958,4IEV1@91061 NA|NA|NA PGHMIELC_00633 220668.lp_1301 4.1e-212 743.8 Lactobacillaceae metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCV@1239,3F3T0@33958,4HB33@91061,COG0192@1,COG0192@2 NA|NA|NA H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme PGHMIELC_00634 220668.lp_1302 1.4e-278 964.9 Lactobacillaceae bmr3 Bacteria 1VSW8@1239,3F4AW@33958,4HUQC@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_00635 220668.lp_1303a 4.2e-139 504.2 Lactobacillaceae ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 1UI5M@1239,3F4B0@33958,4ISEJ@91061,COG2911@1,COG2911@2,COG5492@1,COG5492@2 NA|NA|NA N Cell shape-determining protein MreB PGHMIELC_00636 220668.lp_1310 0.0 1093.2 Lactobacillaceae Bacteria 1UIXE@1239,3F5JK@33958,4ISVQ@91061,COG4627@1,COG4627@2 NA|NA|NA S Pfam Methyltransferase PGHMIELC_00637 220668.lp_1311 1.8e-268 931.4 Lactobacillaceae tagE2 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1V1TS@1239,3FC16@33958,4HG8T@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 PGHMIELC_00638 220668.lp_1312 2.4e-297 1027.3 Lactobacillaceae tagE3 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1UZU7@1239,3FC17@33958,4H9N9@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 PGHMIELC_00639 220668.lp_1313 7.2e-29 132.5 Lactobacillaceae Bacteria 1U6I4@1239,29PFH@1,30ADN@2,3F7YN@33958,4IGAF@91061 NA|NA|NA PGHMIELC_00640 220668.lp_1314 1e-93 349.4 Lactobacillaceae ytqB 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 1UHQD@1239,3F6K1@33958,4HIMC@91061,COG0144@1,COG0144@2 NA|NA|NA J Putative rRNA methylase PGHMIELC_00641 220668.lp_1315 6.7e-124 449.9 Lactobacillaceae 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1VF2U@1239,3F5CM@33958,4HNXR@91061,COG0671@1,COG0671@2 NA|NA|NA I Acid phosphatase homologues PGHMIELC_00642 220668.lp_1316 0.0 1690.2 Lactobacillaceae leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TP0Y@1239,3F46M@33958,4HAG1@91061,COG0495@1,COG0495@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family PGHMIELC_00643 220668.lp_1317 3e-301 1040.4 Lactobacillaceae ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03328,ko:K06409 ko00000,ko02000 2.A.66.2,2.A.66.2.14 Bacteria 1TNYX@1239,3F404@33958,4H9RY@91061,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein PGHMIELC_00644 220668.lp_1319 1.8e-136 491.9 Lactobacillaceae rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 ko00000,ko01000,ko03009 Bacteria 1TQZ2@1239,3F41G@33958,4H9VU@91061,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family PGHMIELC_00645 220668.lp_1320 6.4e-151 540.0 Lactobacillaceae nnrD 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 1TNZE@1239,3F480@33958,4HBZC@91061,COG0063@1,COG0063@2 NA|NA|NA H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration PGHMIELC_00646 220668.lp_1321 1.1e-272 945.3 Lactobacillaceae pepV 3.5.1.18 ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 M00016 R00899,R02734,R04951 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPEG@1239,3F3UV@33958,4HC14@91061,COG0624@1,COG0624@2 NA|NA|NA E dipeptidase PepV PGHMIELC_00647 220668.lp_1322 4.1e-84 317.4 Lactobacillaceae uspA ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1VMC9@1239,3F6UZ@33958,4HYXY@91061,COG0589@1,COG0589@2 NA|NA|NA T Belongs to the universal stress protein A family PGHMIELC_00648 220668.lp_1324 1.8e-201 708.4 Lactobacillaceae ugpC 3.6.3.20 ko:K05816,ko:K10111,ko:K10112,ko:K17240 ko02010,map02010 M00194,M00196,M00197,M00198,M00200,M00201,M00204,M00206,M00207,M00491,M00599,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1,3.A.1.1.3,3.A.1.1.38 Bacteria 1TP2M@1239,3FC3B@33958,4HA50@91061,COG3842@1,COG3842@2 NA|NA|NA E Belongs to the ABC transporter superfamily PGHMIELC_00649 220668.lp_1325 6.8e-173 613.2 Lactobacillaceae ugpA ko:K02025,ko:K05814,ko:K15771 ko02010,map02010 M00198,M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.3 Bacteria 1TSIQ@1239,3FCAR@33958,4HC0D@91061,COG1175@1,COG1175@2 NA|NA|NA U Binding-protein-dependent transport system inner membrane component PGHMIELC_00650 220668.lp_1326 1.1e-150 539.3 Lactobacillaceae ugpE ko:K02026,ko:K05815 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 Bacteria 1TR0I@1239,3F4Q5@33958,4HB8C@91061,COG0395@1,COG0395@2 NA|NA|NA G ABC transporter permease PGHMIELC_00651 220668.lp_1327 2.3e-108 398.3 Lactobacillaceae ugpB ko:K05813 ko02010,map02010 M00198 ko00000,ko00001,ko00002,ko02000 3.A.1.1.3 Bacteria 1TS64@1239,3FC76@33958,4HARC@91061,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein PGHMIELC_00652 220668.lp_1327 5.9e-140 503.4 Lactobacillaceae ugpB ko:K05813 ko02010,map02010 M00198 ko00000,ko00001,ko00002,ko02000 3.A.1.1.3 Bacteria 1TS64@1239,3FC76@33958,4HARC@91061,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein PGHMIELC_00653 220668.lp_1328 9.9e-126 456.1 Lactobacillaceae glpQ1 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1V3W4@1239,3F4E3@33958,4HFNQ@91061,COG0584@1,COG0584@2 NA|NA|NA C glycerophosphoryl diester phosphodiesterase PGHMIELC_00654 220668.lp_1329 3.8e-119 434.1 Lactobacillaceae dck 2.7.1.74 ko:K00893 ko00230,ko00240,ko01100,map00230,map00240,map01100 R00185,R01666 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TPJ1@1239,3F4MY@33958,4HA9N@91061,COG1428@1,COG1428@2 NA|NA|NA F deoxynucleoside kinase PGHMIELC_00655 220668.lp_1330 5.5e-41 173.7 Lactobacillaceae mscL GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 ko:K03282 ko00000,ko02000 1.A.22.1 Bacteria 1VA14@1239,3F6YZ@33958,4HKIA@91061,COG1970@1,COG1970@2 NA|NA|NA M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell PGHMIELC_00656 220668.lp_1332 1.8e-179 636.7 Lactobacillaceae XK27_06930 ko:K01421 ko00000 Bacteria 1TQ15@1239,3F3Y3@33958,4H9T9@91061,COG1511@1,COG1511@2 NA|NA|NA V domain protein PGHMIELC_00658 220668.lp_1334 2.5e-127 461.5 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1WK@1239,3F78J@33958,4ISVR@91061,COG0842@1,COG0842@2 NA|NA|NA V Transport permease protein PGHMIELC_00659 220668.lp_1335 2.3e-156 558.1 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TRNT@1239,3F5U0@33958,4HB3P@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter PGHMIELC_00660 220668.lp_1336 1.3e-174 619.0 Lactobacillaceae ko:K01990,ko:K21397 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TSA4@1239,3F6CY@33958,4HD29@91061,COG1131@1,COG1131@2,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain PGHMIELC_00661 220668.lp_1339 9.1e-155 552.7 Lactobacillaceae msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 ko00000,ko01000 Bacteria 1TS05@1239,3FC52@33958,4HAPI@91061,COG0225@1,COG0225@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine PGHMIELC_00662 220668.lp_1341 1.6e-64 251.9 Lactobacillaceae Bacteria 1U80Z@1239,3FAED@33958,4IHYD@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance PGHMIELC_00663 220668.lp_1342 3.5e-117 427.6 Lactobacillaceae Bacteria 1U7GB@1239,3F9M1@33958,4IHCH@91061,COG0702@1,COG0702@2 NA|NA|NA GM NAD(P)H-binding PGHMIELC_00664 220668.lp_1343 1.2e-158 565.8 Bacilli ypaH Bacteria 1TR6G@1239,4HAMD@91061,COG0697@1,COG0697@2 NA|NA|NA EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily PGHMIELC_00665 220668.lp_1353 7.6e-149 533.1 Lactobacillaceae Bacteria 1UYC4@1239,3F5R1@33958,4HGTM@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase PGHMIELC_00666 220668.lp_1354 1.7e-108 398.7 Lactobacillaceae Bacteria 1U5EA@1239,29NQX@1,309NV@2,3F5Q3@33958,4IF5Q@91061 NA|NA|NA PGHMIELC_00667 220668.lp_1355 2.2e-224 784.6 Lactobacillaceae pltK 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1V1ET@1239,3F71I@33958,4HGNA@91061,COG3290@1,COG3290@2 NA|NA|NA T GHKL domain PGHMIELC_00668 220668.lp_1356 1.6e-137 495.4 Lactobacillaceae pltR ko:K07707 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko02022 Bacteria 1V392@1239,3F3VI@33958,4HHAI@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain PGHMIELC_00669 220668.lp_1357 4.5e-55 220.3 Lactobacillaceae Bacteria 1U66V@1239,29P6H@1,30A4M@2,3F77U@33958,4IFXB@91061 NA|NA|NA PGHMIELC_00670 220668.lp_1358 2.5e-59 234.6 Lactobacillaceae Bacteria 1U5ZB@1239,29P15@1,309ZB@2,3F6R9@33958,4IFNC@91061 NA|NA|NA PGHMIELC_00671 220668.lp_1359 1.9e-113 415.2 Lactobacillaceae ko:K07052 ko00000 Bacteria 1VFRX@1239,3F4Q0@33958,4HRQQ@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity PGHMIELC_00672 220668.lp_1360 1.6e-85 322.0 Lactobacillaceae ohrR Bacteria 1V6G0@1239,3F74F@33958,4HKQR@91061,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein PGHMIELC_00673 220668.lp_1362 1.9e-89 335.1 Lactobacillaceae Bacteria 1UHI8@1239,29VVQ@1,30HDJ@2,3F68W@33958,4IFDH@91061 NA|NA|NA PGHMIELC_00674 220668.lp_1363 2.5e-46 191.0 Lactobacillaceae Bacteria 1W0FC@1239,2FCT0@1,344W0@2,3F7QR@33958,4HXX0@91061 NA|NA|NA PGHMIELC_00675 220668.lp_1364 0.0 1508.8 Lactobacillaceae uvrA2 Bacteria 1TR1H@1239,3F50Y@33958,4H9RE@91061,COG0178@1,COG0178@2 NA|NA|NA L ABC transporter PGHMIELC_00677 1400520.LFAB_05365 2.6e-211 741.1 Lactobacillaceae Bacteria 1TPE1@1239,3F3NJ@33958,4HA65@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family PGHMIELC_00684 755164.D6PSS8_9CAUD 1.5e-36 159.1 Caudovirales Viruses 4QPUR@28883,4QX5A@35237 NA|NA|NA S Pfam:Peptidase_M78 PGHMIELC_00685 543734.LCABL_10840 8e-25 119.8 Lactobacillaceae ps115 Bacteria 1VEP9@1239,3F871@33958,4HPCR@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins PGHMIELC_00687 1300150.EMQU_2524 1.3e-62 246.5 Enterococcaceae Bacteria 1TT7W@1239,4B38D@81852,4I4B6@91061,COG3646@1,COG3646@2 NA|NA|NA S ORF6C domain PGHMIELC_00689 1396141.BATP01000060_gene4572 1.3e-06 60.5 Verrucomicrobia Bacteria 2CEX8@1,32AEQ@2,46W6S@74201 NA|NA|NA PGHMIELC_00690 1400520.LFAB_05430 8.9e-56 222.6 Lactobacillaceae Bacteria 1VDBG@1239,3F6R0@33958,4HKZG@91061,COG4707@1,COG4707@2 NA|NA|NA S Domain of unknown function (DUF771) PGHMIELC_00695 1136177.KCA1_1069 4.6e-131 473.8 Lactobacillaceae Bacteria 1VBY4@1239,2CV27@1,32SWP@2,3F5Z8@33958,4HQXW@91061 NA|NA|NA S Putative HNHc nuclease PGHMIELC_00696 1136177.KCA1_1070 3.6e-71 275.0 Bacilli Bacteria 1TQT6@1239,4HHS9@91061,COG3935@1,COG3935@2 NA|NA|NA L DnaD domain protein PGHMIELC_00697 1400520.LFAB_09190 2.4e-144 518.1 Lactobacillaceae pi346 ko:K02315 ko00000,ko03032 Bacteria 1V36Z@1239,3F6VF@33958,4HXKM@91061,COG1484@1,COG1484@2 NA|NA|NA L IstB-like ATP binding protein PGHMIELC_00699 1400520.LFAB_09180 3e-45 187.6 Lactobacillaceae Bacteria 1U7MG@1239,2A444@1,30SP6@2,3F9WP@33958,4IHIN@91061 NA|NA|NA PGHMIELC_00700 1400520.LFAB_09175 4.1e-17 93.2 Lactobacillaceae Bacteria 1U7XI@1239,29QDK@1,30BCW@2,3FAAM@33958,4IHUX@91061 NA|NA|NA PGHMIELC_00701 220668.lp_0653 8.2e-26 123.2 Lactobacillaceae Bacteria 1VKPB@1239,2EGZP@1,33ART@2,3F8RA@33958,4HR69@91061 NA|NA|NA S YopX protein PGHMIELC_00703 220668.lp_0655 1.4e-17 94.7 Lactobacillaceae Bacteria 1U76U@1239,29PXZ@1,30AWD@2,3F91U@33958,4IH1M@91061 NA|NA|NA PGHMIELC_00704 1400520.LFAB_09145 4.3e-64 250.8 Lactobacillaceae Bacteria 1VMGI@1239,2E42J@1,32YZ1@2,3F8JP@33958,4HRUN@91061 NA|NA|NA S Transcriptional regulator, RinA family PGHMIELC_00706 220668.lp_2425 8.6e-13 79.0 Lactobacillaceae Bacteria 1W4M5@1239,2911N@1,2ZNP8@2,3F95E@33958,4I18X@91061 NA|NA|NA PGHMIELC_00707 1400520.LFAB_09130 6.4e-69 266.9 Lactobacillaceae ko:K07451 ko00000,ko01000,ko02048 Bacteria 1VQIP@1239,3F6KP@33958,4HM74@91061,COG1403@1,COG1403@2 NA|NA|NA L HNH nucleases PGHMIELC_00708 146269.A8YQN4_9CAUD 5.2e-29 134.4 Siphoviridae Viruses 4QAIU@10239,4QKM7@10699,4QPDE@28883,4QUQC@35237 NA|NA|NA S HNH endonuclease PGHMIELC_00709 1400520.LFAB_09125 4.7e-79 300.4 Lactobacillaceae Bacteria 1VW7W@1239,3F43B@33958,4HR5B@91061,COG3747@1,COG3747@2 NA|NA|NA L Phage terminase, small subunit PGHMIELC_00710 947981.E9LUP9_9CAUD 0.0 1240.3 Siphoviridae Viruses 4QBV3@10239,4QKW5@10699,4QPPJ@28883,4QW0W@35237 NA|NA|NA S Phage Terminase PGHMIELC_00711 278197.PEPE_1004 1.1e-24 118.6 Lactobacillaceae Bacteria 1W2BH@1239,2DDZ9@1,2ZJX7@2,3F8QY@33958,4I25Q@91061 NA|NA|NA S Protein of unknown function (DUF1056) PGHMIELC_00712 1400520.LFAB_09110 6.2e-224 783.1 Lactobacillaceae Bacteria 1UY1R@1239,3FB4M@33958,4HDQZ@91061,COG4695@1,COG4695@2 NA|NA|NA S Phage portal protein PGHMIELC_00713 947981.E9LUQ2_9CAUD 8.4e-126 456.4 Siphoviridae Viruses 4QBNM@10239,4QKV6@10699,4QPUI@28883,4QUT2@35237 NA|NA|NA S Clp protease PGHMIELC_00714 1400520.LFAB_09100 2.6e-209 734.6 Lactobacillaceae Bacteria 1UACS@1239,3FB8A@33958,4HEAS@91061,COG4653@1,COG4653@2 NA|NA|NA S Phage capsid family PGHMIELC_00715 947981.E9LUQ4_9CAUD 3.6e-52 210.7 Siphoviridae Viruses 4QBCW@10239,4QKNA@10699,4QPS7@28883,4QUN6@35237 NA|NA|NA S Phage gp6-like head-tail connector protein PGHMIELC_00716 349123.Lreu23DRAFT_3162 1.4e-25 122.5 Lactobacillaceae Bacteria 1U6GF@1239,29PE6@1,30ACC@2,3F7VC@33958,4IG8K@91061 NA|NA|NA S Phage head-tail joining protein PGHMIELC_00717 1605.Lani381_0379 9.1e-40 169.9 Lactobacillaceae Bacteria 1U707@1239,2C8I5@1,30AR4@2,3F8T1@33958,4IGUI@91061 NA|NA|NA PGHMIELC_00718 349123.Lreu23DRAFT_3164 5.9e-27 127.1 Lactobacillaceae Bacteria 1U69R@1239,29P8Q@1,30A6U@2,3F7DX@33958,4IG0W@91061 NA|NA|NA PGHMIELC_00719 1605.Lani381_0377 1e-71 276.6 Lactobacillaceae Bacteria 1V7ZH@1239,2AZAN@1,31RHY@2,3F4AS@33958,4HJVX@91061 NA|NA|NA S Phage tail tube protein PGHMIELC_00722 947981.E9LUR1_9CAUD 0.0 1790.4 Siphoviridae Viruses 4QAK6@10239,4QKKV@10699,4QPBY@28883,4QUP9@35237 NA|NA|NA S peptidoglycan catabolic process PGHMIELC_00723 947981.E9LUR2_9CAUD 1.3e-225 789.3 Siphoviridae GO:0005575,GO:0019012,GO:0044423,GO:0098015 Viruses 4QBF8@10239,4QKN2@10699,4QPI9@28883,4QUS7@35237 NA|NA|NA S Phage tail protein PGHMIELC_00724 1400520.LFAB_09050 2.9e-169 601.3 Lactobacillaceae Bacteria 1V7K6@1239,3F5SM@33958,4HJ7J@91061,COG4926@1,COG4926@2 NA|NA|NA S Phage minor structural protein PGHMIELC_00725 278197.PEPE_0991 1.2e-105 390.2 Lactobacillaceae Bacteria 1V7K6@1239,3F5SM@33958,4HJ7J@91061,COG4926@1,COG4926@2 NA|NA|NA S Phage minor structural protein PGHMIELC_00726 1225795.K4I0E3_9CAUD 2.4e-160 572.8 Caudovirales Viruses 4QCAX@10239,4QTMU@28883 NA|NA|NA PGHMIELC_00729 1400520.LFAB_09030 4.5e-53 213.8 Lactobacillaceae Bacteria 1UIXH@1239,2B254@1,31UNB@2,3F55T@33958,4I0AP@91061 NA|NA|NA PGHMIELC_00730 1400520.LFAB_09025 3.1e-176 624.4 Bacilli 3.5.1.28 ko:K01449,ko:K14196 ko05150,map05150 R04112 RC00064,RC00141 ko00000,ko00001,ko01000 Bacteria 1V16P@1239,4HF99@91061,COG1388@1,COG1388@2,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 PGHMIELC_00731 1136177.KCA1_1106 3.3e-37 160.6 Lactobacillaceae Bacteria 1W39V@1239,2C0XI@1,2ZJRZ@2,3F7TU@33958,4I12U@91061 NA|NA|NA S Haemolysin XhlA PGHMIELC_00734 220668.lp_1369 5.9e-52 210.3 Lactobacillaceae Bacteria 1U5W7@1239,29NZD@1,309XI@2,3F6M7@33958,4IFJW@91061 NA|NA|NA PGHMIELC_00735 220668.lp_1370 3.5e-10 69.7 Lactobacillaceae Bacteria 1U871@1239,29QJD@1,30BIY@2,3FAMK@33958,4II4R@91061 NA|NA|NA PGHMIELC_00736 220668.lp_1371 2.1e-180 638.3 Lactobacillaceae Bacteria 1U57U@1239,2CDNX@1,309JA@2,3F51R@33958,4IEZ2@91061 NA|NA|NA PGHMIELC_00737 220668.lp_1372 1.9e-89 335.1 Lactobacillaceae gtcA GO:0000166,GO:0003674,GO:0003824,GO:0003870,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009987,GO:0016020,GO:0016410,GO:0016491,GO:0016620,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0016903,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 Bacteria 1VESW@1239,3F4GH@33958,4HNK7@91061,COG2246@1,COG2246@2 NA|NA|NA S Teichoic acid glycosylation protein PGHMIELC_00738 220668.lp_1373 3.6e-58 230.7 Lactobacillaceae Bacteria 1U631@1239,2DKNF@1,30A1X@2,3F6XA@33958,4IFSA@91061 NA|NA|NA S Protein of unknown function (DUF1516) PGHMIELC_00739 220668.lp_1374 0.0 1206.0 Bacilli yitJ 1.5.1.20,2.1.1.10,2.1.1.13 ko:K00297,ko:K00547,ko:K00548 ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,ko01523,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230,map01523 M00017,M00377 R00650,R00946,R01224,R07168,R09365 RC00003,RC00035,RC00081,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0504 Bacteria 1TPYV@1239,4HAB5@91061,COG0646@1,COG0646@2,COG0685@1,COG0685@2 NA|NA|NA E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine PGHMIELC_00740 220668.lp_1375 0.0 1541.9 Lactobacillaceae metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131 Bacteria 1TP2H@1239,3F3VW@33958,4H9QC@91061,COG0620@1,COG0620@2 NA|NA|NA E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation PGHMIELC_00741 220668.lp_1377 1.4e-306 1058.1 Lactobacillaceae Bacteria 1UG61@1239,3F5IK@33958,4IF3M@91061,COG3551@1,COG3551@2 NA|NA|NA S Protein conserved in bacteria PGHMIELC_00742 220668.lp_1378 1.3e-229 802.0 Lactobacillaceae sat 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR4C@1239,3F57K@33958,4HC20@91061,COG2046@1,COG2046@2 NA|NA|NA H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms PGHMIELC_00743 220668.lp_1379 2.5e-112 411.4 Lactobacillaceae cysC GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016740,GO:0016772,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 2.7.1.25,2.7.7.4 ko:K00860,ko:K00955 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQXK@1239,3F51N@33958,4HB96@91061,COG0529@1,COG0529@2 NA|NA|NA F Catalyzes the synthesis of activated sulfate PGHMIELC_00744 220668.lp_1380 1.5e-175 622.1 Lactobacillaceae nrnA GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPXX@1239,3F5VH@33958,4H9ZW@91061,COG0618@1,COG0618@2 NA|NA|NA S DHHA1 domain PGHMIELC_00745 220668.lp_1381 3.9e-304 1050.0 Lactobacillaceae astA 2.8.2.22 ko:K01023 ko00000,ko01000 Bacteria 1TSWC@1239,28MBK@1,2ZAQ1@2,3F50E@33958,4HCSW@91061 NA|NA|NA M Arylsulfotransferase Ig-like domain PGHMIELC_00746 220668.lp_1385 0.0 1083.2 Lactobacillaceae yfbS ko:K03281,ko:K03319 ko00000 2.A.47,2.A.49 Bacteria 1UI5K@1239,3F5S9@33958,4HC1Q@91061,COG0471@1,COG0471@2,COG0569@1,COG0569@2 NA|NA|NA P Sodium:sulfate symporter transmembrane region PGHMIELC_00747 220668.lp_1386 2.1e-244 851.3 Lactobacillaceae dinF Bacteria 1TNZN@1239,3FC3X@33958,4HANM@91061,COG0534@1,COG0534@2 NA|NA|NA V MatE PGHMIELC_00748 1400520.LFAB_08900 1.9e-31 141.4 Bacilli Bacteria 1W5PP@1239,2DZ2C@1,34C6W@2,4HZIR@91061 NA|NA|NA PGHMIELC_00751 220668.lp_1390 7.7e-79 299.7 Lactobacillaceae elaA GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 ko:K02348 ko00000 Bacteria 1VAJY@1239,3FB6K@33958,4HIH7@91061,COG2153@1,COG2153@2 NA|NA|NA S Acetyltransferase (GNAT) domain PGHMIELC_00752 220668.lp_1391 0.0 1111.7 Lactobacillaceae argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPEZ@1239,3F4DE@33958,4HAR3@91061,COG0018@1,COG0018@2 NA|NA|NA J Arginyl-tRNA synthetase PGHMIELC_00753 220668.lp_1392 1.4e-81 308.9 Lactobacillaceae Bacteria 1U62Y@1239,29P52@1,30S4B@2,3F6X6@33958,4IFS3@91061 NA|NA|NA PGHMIELC_00754 220668.lp_1393 0.0 1231.1 Lactobacillaceae yhcA ko:K02003,ko:K02004,ko:K05685 ko02010,map02010 M00258,M00709 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 Bacteria 1TPBJ@1239,3F56Z@33958,4HBK7@91061,COG0577@1,COG0577@2,COG1136@1,COG1136@2 NA|NA|NA V MacB-like periplasmic core domain PGHMIELC_00755 60520.HR47_02745 7.6e-107 393.3 Lactobacillaceae Bacteria 1U61V@1239,29P2X@1,30A14@2,3F6UE@33958,4IFQT@91061 NA|NA|NA PGHMIELC_00756 220668.lp_1396 0.0 1611.7 Lactobacillaceae Bacteria 1VSHE@1239,3F9EV@33958,4HB6T@91061,COG1221@1,COG1221@2,COG3933@1,COG3933@2 NA|NA|NA K PRD domain PGHMIELC_00757 220668.lp_1397 5.9e-61 240.4 Firmicutes Bacteria 1VEKS@1239,2ECMT@1,336JS@2 NA|NA|NA S Domain of unknown function (DUF3284) PGHMIELC_00758 220668.lp_1398 1.4e-51 208.8 Lactobacillaceae chbA 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 Bacteria 1V9Z6@1239,3F7Q7@33958,4HKFE@91061,COG1447@1,COG1447@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIA subunit PGHMIELC_00759 220668.lp_1399 1.1e-47 195.7 Lactobacillaceae pts15B 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 Bacteria 1TTPX@1239,3F9ZT@33958,4IHM5@91061,COG1440@1,COG1440@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit PGHMIELC_00760 220668.lp_1400 1.6e-244 851.7 Lactobacillaceae pts15C ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 Bacteria 1V0MP@1239,3F9KT@33958,4IPPQ@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane PGHMIELC_00761 220668.lp_1401 1.3e-287 995.0 Lactobacillaceae 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family PGHMIELC_00762 220668.lp_1402 1.8e-32 144.8 Bacteria ko:K08218 ko01501,map01501 M00628 ko00000,ko00001,ko00002,ko02000 2.A.1.25 Bacteria COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_00763 220668.lp_1402 1.9e-158 565.1 Bacteria ko:K08218 ko01501,map01501 M00628 ko00000,ko00001,ko00002,ko02000 2.A.1.25 Bacteria COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_00764 220668.lp_1403 2e-114 418.3 Lactobacillaceae Bacteria 1V4KP@1239,3F6PH@33958,4HIBF@91061,COG1376@1,COG1376@2 NA|NA|NA M ErfK YbiS YcfS YnhG PGHMIELC_00765 220668.lp_1406 4e-34 150.2 Lactobacillaceae dltC GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K02078,ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1U6FX@1239,3F7TR@33958,4IG7W@91061,COG0236@1,COG0236@2 NA|NA|NA J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall PGHMIELC_00766 220668.lp_1407 8.4e-284 982.2 Lactobacillaceae ydfD ko:K00375,ko:K18907 M00700,M00702 ko00000,ko00002,ko01504,ko03000 Bacteria 1TPS5@1239,3F5IE@33958,4HB1C@91061,COG1167@1,COG1167@2 NA|NA|NA K Alanine-glyoxylate amino-transferase PGHMIELC_00767 220668.lp_1409 1.4e-102 379.0 Lactobacillaceae argO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 ko:K06895 ko00000,ko02000 2.A.75.1 iPC815.YPO0918 Bacteria 1V1Q2@1239,3F5RR@33958,4HFYS@91061,COG1279@1,COG1279@2 NA|NA|NA S LysE type translocator PGHMIELC_00768 220668.lp_1410 3.2e-214 750.7 Lactobacillaceae arcT 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 Bacteria 1TQPD@1239,3F3PZ@33958,4HE7P@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase PGHMIELC_00769 220668.lp_1411 4.4e-77 293.9 Lactobacillaceae argR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 ko:K03402 ko00000,ko03000 Bacteria 1VA3U@1239,3F65K@33958,4HPCQ@91061,COG1438@1,COG1438@2 NA|NA|NA K Regulates arginine biosynthesis genes PGHMIELC_00770 220668.lp_1412 2.9e-12 76.6 Lactobacillaceae Bacteria 1U6YI@1239,29PRK@1,30APT@2,3F8QD@33958,4IGSP@91061 NA|NA|NA PGHMIELC_00771 220668.lp_1413 0.0 1331.2 Lactobacillaceae pbp2A 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366,ko:K12555,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1TPM5@1239,3F49Q@33958,4H9SA@91061,COG0744@1,COG0744@2 NA|NA|NA M penicillin-binding protein PGHMIELC_00772 60520.HR47_02660 1e-54 219.2 Lactobacillaceae yheA Bacteria 1VASS@1239,3F822@33958,4HKKC@91061,COG3679@1,COG3679@2 NA|NA|NA S Belongs to the UPF0342 family PGHMIELC_00773 220668.lp_1416 5.7e-233 813.1 Lactobacillaceae yhaO ko:K03547 ko00000,ko03400 Bacteria 1TWMI@1239,3F3PX@33958,4HCA0@91061,COG0420@1,COG0420@2 NA|NA|NA L Ser Thr phosphatase family protein PGHMIELC_00774 220668.lp_1417 0.0 1390.2 Lactobacillaceae Bacteria 1TQP3@1239,3F3PF@33958,4HBCA@91061,COG0419@1,COG0419@2,COG4717@1,COG4717@2 NA|NA|NA L AAA domain PGHMIELC_00775 220668.lp_1418 2.9e-187 661.0 Lactobacillaceae yhaM GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 ko:K03698 ko00000,ko01000,ko03019 Bacteria 1TPIU@1239,3F4SF@33958,4HB1M@91061,COG3481@1,COG3481@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. PGHMIELC_00776 220668.lp_1419 8.7e-215 752.7 Lactobacillaceae Bacteria 1U7DR@1239,29Q2Y@1,30B1J@2,3F9FQ@33958,4IH9N@91061 NA|NA|NA PGHMIELC_00777 220668.lp_1420 5.2e-181 640.2 Lactobacillaceae 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 1U9Z0@1239,3F7HQ@33958,4HRFD@91061,COG0793@1,COG0793@2 NA|NA|NA M Peptidase family S41 PGHMIELC_00778 220668.lp_1422 1.2e-177 629.0 Lactobacillaceae Bacteria 1U35Y@1239,3FBI9@33958,4HCXK@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain PGHMIELC_00779 220668.lp_1424 2.1e-111 408.3 Lactobacillaceae 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 1TT2S@1239,3F50W@33958,4I3MY@91061,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase PGHMIELC_00780 220668.lp_1425 0.0 1583.9 Lactobacillaceae 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAR@1239,3F53U@33958,4HAXN@91061,COG0431@1,COG0431@2,COG1053@1,COG1053@2,COG3976@1,COG3976@2 NA|NA|NA C FAD binding domain PGHMIELC_00781 220668.lp_1426 4.2e-98 364.0 Lactobacillaceae Bacteria 1U5GR@1239,2CG2Y@1,309PX@2,3F5WC@33958,4IF7G@91061 NA|NA|NA PGHMIELC_00782 220668.lp_1427 6e-76 290.0 Lactobacillaceae 2.4.2.6 ko:K08728 ko00240,map00240 R02806 RC00063 ko00000,ko00001,ko01000 Bacteria 1VB4I@1239,3F663@33958,4IRXT@91061,COG3613@1,COG3613@2 NA|NA|NA F Nucleoside 2-deoxyribosyltransferase PGHMIELC_00783 1400520.LFAB_07700 1.9e-160 572.4 Lactobacillaceae Bacteria 1VU2I@1239,3F475@33958,4HHZT@91061,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor PGHMIELC_00784 1400520.LFAB_07705 4.8e-104 384.0 Lactobacillaceae Bacteria 1TS81@1239,3F3JF@33958,4H9NE@91061,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C terminal PGHMIELC_00785 1400520.LFAB_15670 2.2e-61 242.3 Lactobacillaceae 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 R02029,R05627 RC00002,RC00017 ko00000,ko00001,ko01000,ko01011 Bacteria 1VY85@1239,3F4DD@33958,4HXM4@91061,COG0671@1,COG0671@2 NA|NA|NA I phosphatase PGHMIELC_00786 1400520.LFAB_07695 2.6e-132 478.4 Lactobacillaceae yfdH 2.4.2.53 ko:K10012,ko:K12999,ko:K13670 ko00520,ko01503,map00520,map01503 M00721,M00761 R07661 RC00005,RC02954 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko02000 4.D.2.1.8 GT2 Bacteria 1UHWE@1239,3F3JX@33958,4ISA4@91061,COG1216@1,COG1216@2 NA|NA|NA M Glycosyltransferase, group 2 family protein PGHMIELC_00787 1400520.LFAB_07735 1.3e-79 302.8 Lactobacillaceae dedA ko:K03975 ko00000 Bacteria 1UZ4P@1239,3F4KG@33958,4HG3F@91061,COG0586@1,COG0586@2 NA|NA|NA S SNARE-like domain protein PGHMIELC_00788 220668.lp_1430 1.8e-184 651.7 Lactobacillaceae ykoT ko:K20534 ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 Bacteria 1TPR3@1239,3F3X7@33958,4HC2Z@91061,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 PGHMIELC_00789 220668.lp_1431 0.0 1293.9 Lactobacillaceae Bacteria 1UYWB@1239,3FB5U@33958,4HE3A@91061,COG1807@1,COG1807@2 NA|NA|NA M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family PGHMIELC_00790 220668.lp_1433 3.9e-69 267.3 Lactobacillaceae Bacteria 1UUX4@1239,2BHDE@1,32BFD@2,3FA1Z@33958,4I3SI@91061 NA|NA|NA S NUDIX domain PGHMIELC_00791 220668.lp_1435 0.0 1661.7 Lactobacillaceae Bacteria 1TRR1@1239,3F49G@33958,4HBW6@91061,COG4485@1,COG4485@2 NA|NA|NA S membrane PGHMIELC_00792 60520.HR47_04355 1.1e-171 609.4 Lactobacillaceae ribD GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 1.1.1.193,3.5.4.26 ko:K00082,ko:K01498,ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1624,iLJ478.TM1828 Bacteria 1TP4F@1239,3F4X5@33958,4HBNA@91061,COG0117@1,COG0117@2,COG1985@1,COG1985@2 NA|NA|NA H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate PGHMIELC_00793 60520.HR47_04360 1.8e-86 325.5 Lactobacillaceae ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9,3.5.4.25,4.1.99.12 ko:K00793,ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00066,R00425,R07281 RC00293,RC00958,RC00960,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS08950,iYO844.BSU23270 Bacteria 1V1EP@1239,3F6M0@33958,4HC7B@91061,COG0307@1,COG0307@2 NA|NA|NA H Riboflavin synthase PGHMIELC_00794 220668.lp_1437 3.1e-223 780.8 Lactobacillaceae ribBA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS10830,iSB619.SA_RS08945 Bacteria 1TPH9@1239,3F4EB@33958,4H9PW@91061,COG0108@1,COG0108@2,COG0807@1,COG0807@2 NA|NA|NA H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate PGHMIELC_00795 220668.lp_1438 1.4e-81 308.9 Lactobacillaceae ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1825,iSB619.SA_RS08940,iSFV_1184.SFV_0380 Bacteria 1V1DA@1239,3F70X@33958,4HFRA@91061,COG0054@1,COG0054@2 NA|NA|NA H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin PGHMIELC_00796 220668.lp_1439 9.3e-106 389.4 Lactobacillaceae GBS0088 ko:K09962 ko00000 Bacteria 1V1YD@1239,3F65A@33958,4HGK6@91061,COG3575@1,COG3575@2 NA|NA|NA S Nucleotidyltransferase PGHMIELC_00797 220668.lp_1440 1.4e-106 392.1 Lactobacillaceae Bacteria 1UPXG@1239,2AYWY@1,31R2N@2,3F66A@33958,4IVCM@91061 NA|NA|NA PGHMIELC_00798 220668.lp_1442 5.1e-116 423.7 Lactobacillaceae flpA 4.1.99.16,4.2.3.22,4.2.3.75 ko:K10187,ko:K21562 ko00909,ko01100,ko01110,map00909,map01100,map01110 R07647,R07648,R08543,R09487 RC01832,RC02159,RC02160,RC02183,RC02425,RC02552 ko00000,ko00001,ko01000,ko03000 Bacteria 1TVBM@1239,3F4PI@33958,4HEJG@91061,COG0664@1,COG0664@2 NA|NA|NA K helix_turn_helix, cAMP Regulatory protein PGHMIELC_00799 220668.lp_1443 3.3e-112 411.0 Lactobacillaceae Bacteria 1V2M4@1239,3F6MM@33958,4HMH5@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family PGHMIELC_00800 220668.lp_1445 9.4e-242 842.4 Lactobacillaceae npr 1.11.1.1 ko:K05910 ko00000,ko01000 Bacteria 1TPWW@1239,3F449@33958,4H9U7@91061,COG0446@1,COG0446@2 NA|NA|NA C NADH oxidase PGHMIELC_00801 220668.lp_1446 0.0 1723.0 Lactobacillaceae Bacteria 1TVEG@1239,2DIQK@1,303XB@2,3F8IH@33958,4HT2E@91061 NA|NA|NA PGHMIELC_00802 220668.lp_1447 7.9e-61 239.6 Lactobacillaceae Bacteria 1U7JB@1239,29Q62@1,30B4Z@2,3F9T8@33958,4IHG8@91061 NA|NA|NA PGHMIELC_00803 220668.lp_1448 1.4e-192 678.7 Lactobacillaceae Bacteria 1U7CK@1239,3F9CZ@33958,4IH80@91061,COG4072@1,COG4072@2 NA|NA|NA S Fn3-like domain PGHMIELC_00804 220668.lp_1449 3.4e-102 377.9 Lactobacillaceae Bacteria 1U57B@1239,2F5DN@1,33XZI@2,3F8HS@33958,4IEYS@91061 NA|NA|NA S WxL domain surface cell wall-binding PGHMIELC_00805 220668.lp_1450 3.5e-78 298.1 Lactobacillaceae Bacteria 1U7EE@1239,29Q3B@1,30B20@2,3F9GY@33958,4IHAA@91061 NA|NA|NA S WxL domain surface cell wall-binding PGHMIELC_00806 220668.lp_1452 3.3e-129 468.0 Lactobacillaceae prsA 5.2.1.8 ko:K02597,ko:K07533 ko00000,ko01000,ko03110 Bacteria 1TX3R@1239,3F45W@33958,4HC85@91061,COG0760@1,COG0760@2 NA|NA|NA M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins PGHMIELC_00807 220668.lp_1453 3.5e-39 167.5 Lactobacillaceae Bacteria 1U66Y@1239,29P6J@1,30A4P@2,3F77Y@33958,4IFXE@91061 NA|NA|NA PGHMIELC_00808 220668.lp_1454 9.9e-82 309.3 Lactobacillaceae hit ko:K02503 ko00000,ko04147 Bacteria 1V9ZJ@1239,3F6K5@33958,4HIG2@91061,COG0537@1,COG0537@2 NA|NA|NA FG histidine triad PGHMIELC_00809 220668.lp_1455 1.6e-134 485.3 Lactobacillaceae ecsA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQIH@1239,3F444@33958,4HA2B@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter, ATP-binding protein PGHMIELC_00810 220668.lp_1456 4.8e-224 783.5 Lactobacillaceae ecsB ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1VG@1239,3F4HH@33958,4HG1K@91061,COG4473@1,COG4473@2 NA|NA|NA U ABC transporter PGHMIELC_00811 220668.lp_1457 3.2e-152 544.3 Lactobacillaceae ytmP 2.7.1.89 ko:K07251 ko00730,ko01100,map00730,map01100 R02134 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1UMFY@1239,3F4GU@33958,4HBF9@91061,COG0510@1,COG0510@2 NA|NA|NA M Choline/ethanolamine kinase PGHMIELC_00812 220668.lp_1458 9e-121 439.5 Lactobacillaceae trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33 ko:K02493,ko:K03439 R10806 RC00003,RC03279 ko00000,ko01000,ko03012,ko03016 Bacteria 1TQCA@1239,3F3QM@33958,4HC08@91061,COG0220@1,COG0220@2 NA|NA|NA J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA PGHMIELC_00813 220668.lp_1459 1.6e-54 218.4 Lactobacillaceae ytzB Bacteria 1VEIQ@1239,3FB6P@33958,4HNS2@91061,COG5584@1,COG5584@2 NA|NA|NA S Peptidase propeptide and YPEB domain PGHMIELC_00814 220668.lp_1460 5.3e-113 413.7 Lactobacillaceae pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890,ko:K06878 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1V3R1@1239,3F58U@33958,4HHBI@91061,COG0073@1,COG0073@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily PGHMIELC_00815 220668.lp_1461 0.0 1313.5 Lactobacillaceae sftA ko:K03466 ko00000,ko03036 3.A.12 Bacteria 1TPJR@1239,3F441@33958,4HA1S@91061,COG1674@1,COG1674@2 NA|NA|NA D Belongs to the FtsK SpoIIIE SftA family PGHMIELC_00816 220668.lp_1462 1.1e-253 882.1 Lactobacillaceae mpl GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464 6.3.2.4,6.3.2.45,6.3.2.8 ko:K01921,ko:K01924,ko:K02558 ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502 R01150,R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iSDY_1059.SDY_4251 Bacteria 1TQ5H@1239,3F49J@33958,4HAR4@91061,COG0773@1,COG0773@2 NA|NA|NA M Belongs to the MurCDEF family PGHMIELC_00817 220668.lp_1465 7.9e-21 105.5 Lactobacillaceae Bacteria 1U75W@1239,29PXD@1,30AVR@2,3F90N@33958,4IH0H@91061 NA|NA|NA S Virus attachment protein p12 family PGHMIELC_00818 220668.lp_1466 0.0 1282.7 Lactobacillaceae feoB ko:K04759 ko00000,ko02000 9.A.8.1 iSB619.SA_RS13395 Bacteria 1TP7E@1239,3F553@33958,4HBCS@91061,COG0370@1,COG0370@2 NA|NA|NA P transporter of a GTP-driven Fe(2 ) uptake system PGHMIELC_00819 220668.lp_1467 1.3e-34 151.8 Lactobacillaceae feoA ko:K04758 ko00000,ko02000 Bacteria 1U69I@1239,3F7DB@33958,4IG0P@91061,COG1918@1,COG1918@2 NA|NA|NA P FeoA domain PGHMIELC_00820 220668.lp_1468 4.2e-144 517.3 Lactobacillaceae sufC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 ko:K09013 ko00000,ko02000 iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710 Bacteria 1TQ98@1239,3F3XT@33958,4HAD9@91061,COG0396@1,COG0396@2 NA|NA|NA O FeS assembly ATPase SufC PGHMIELC_00821 60520.HR47_04540 2.9e-243 847.4 Lactobacillaceae sufD ko:K07033,ko:K09015 ko00000 Bacteria 1TRT0@1239,3F4BR@33958,4HB6W@91061,COG0719@1,COG0719@2 NA|NA|NA O FeS assembly protein SufD PGHMIELC_00822 220668.lp_1470 8.9e-234 815.8 Lactobacillaceae sufS 2.8.1.7,4.4.1.16 ko:K04487,ko:K11717 ko00450,ko00730,ko01100,ko04122,map00450,map00730,map01100,map04122 R03599,R07460,R11528,R11529 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TQ1W@1239,3F3UP@33958,4HA6Z@91061,COG0520@1,COG0520@2 NA|NA|NA E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine PGHMIELC_00823 220668.lp_1471 7.1e-83 313.2 Lactobacillaceae nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 ko:K04488 ko00000 Bacteria 1V3H9@1239,3F6WP@33958,4HIJ0@91061,COG0822@1,COG0822@2 NA|NA|NA C SUF system FeS assembly protein, NifU family PGHMIELC_00824 220668.lp_1472 1.4e-272 944.9 Lactobacillaceae sufB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 ko:K07033,ko:K09014 ko00000 Bacteria 1TQ21@1239,3F44I@33958,4HA1Z@91061,COG0719@1,COG0719@2 NA|NA|NA O assembly protein SufB PGHMIELC_00825 60520.HR47_04600 5.5e-45 186.8 Lactobacillaceae yitW ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1VCAX@1239,3FCDE@33958,4HNBK@91061,COG2151@1,COG2151@2 NA|NA|NA S Iron-sulfur cluster assembly protein PGHMIELC_00826 1136177.KCA1_1260 2.3e-111 408.7 Lactobacillaceae hipB GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K15773 ko00000,ko02048,ko03000 Bacteria 1VDMN@1239,3F5A3@33958,4HDVP@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix PGHMIELC_00827 220668.lp_1507 4.5e-121 440.7 Lactobacillaceae ybhL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06890 ko00000 Bacteria 1V66F@1239,3FBMP@33958,4IR6X@91061,COG0670@1,COG0670@2 NA|NA|NA S Belongs to the BI1 family PGHMIELC_00828 220668.lp_1508 0.0 1721.4 Lactobacillaceae polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1TPKJ@1239,3F3ZA@33958,4H9S7@91061,COG0258@1,COG0258@2,COG0749@1,COG0749@2 NA|NA|NA L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity PGHMIELC_00829 220668.lp_1509 1.5e-157 562.0 Lactobacillaceae fpg 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPM9@1239,3F43E@33958,4H9Q7@91061,COG0266@1,COG0266@2 NA|NA|NA L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates PGHMIELC_00830 220668.lp_1510 7.8e-103 379.8 Lactobacillaceae coaE 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6FS@1239,3F6WF@33958,4HII3@91061,COG0237@1,COG0237@2 NA|NA|NA F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A PGHMIELC_00831 220668.lp_1511 4.6e-91 340.5 Lactobacillaceae nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K07738 ko00000,ko03000 Bacteria 1V3JA@1239,3F65S@33958,4HGXA@91061,COG1327@1,COG1327@2 NA|NA|NA K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes PGHMIELC_00832 220668.lp_1512 2.5e-248 864.4 Lactobacillaceae dnaB ko:K03346 ko00000,ko03032 Bacteria 1TSBB@1239,3F5D7@33958,4H9RI@91061,COG3611@1,COG3611@2 NA|NA|NA L replication initiation and membrane attachment PGHMIELC_00833 220668.lp_1513 3.3e-172 610.9 Lactobacillaceae dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K11144 ko00000,ko03032 Bacteria 1TPZX@1239,3F4JK@33958,4HABS@91061,COG1484@1,COG1484@2 NA|NA|NA L Primosomal protein DnaI PGHMIELC_00834 220668.lp_1514 0.0 1305.4 Lactobacillaceae thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP78@1239,3F3TC@33958,4HABZ@91061,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) PGHMIELC_00835 220668.lp_1515 1.8e-84 318.5 Lactobacillaceae infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 1V1RC@1239,3F4MS@33958,4HFUS@91061,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins PGHMIELC_00836 1136177.KCA1_1289 1.9e-26 124.4 Lactobacillaceae rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02916 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VF5W@1239,3F7CQ@33958,4HNIQ@91061,COG0291@1,COG0291@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL35 family PGHMIELC_00837 220668.lp_1517 7.3e-56 223.0 Lactobacillaceae rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6DB@1239,3F6HZ@33958,4HH2W@91061,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit PGHMIELC_00838 220668.lp_1518 9.9e-57 225.7 Lactobacillaceae Bacteria 1VZDC@1239,2C8G2@1,348DR@2,3F740@33958,4HZ47@91061 NA|NA|NA PGHMIELC_00839 220668.lp_1519 9.4e-239 832.4 Lactobacillaceae yrvN ko:K07478 ko00000 Bacteria 1TPVV@1239,3F44J@33958,4HAIS@91061,COG2256@1,COG2256@2 NA|NA|NA L AAA C-terminal domain PGHMIELC_00840 220668.lp_1521 4.3e-130 470.7 Lactobacillaceae qor 1.1.1.1,1.6.5.5 ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1TRNC@1239,3F48F@33958,4HATC@91061,COG0604@1,COG0604@2 NA|NA|NA C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily PGHMIELC_00841 220668.lp_1522 1e-62 245.7 Lactobacillaceae hxlR Bacteria 1VA9M@1239,3F7S1@33958,4HH0A@91061,COG1733@1,COG1733@2 NA|NA|NA K Transcriptional regulator, HxlR family PGHMIELC_00842 220668.lp_1523 1.5e-135 488.8 Lactobacillaceae racD 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 R00491 RC00302 ko00000,ko00001,ko01000 Bacteria 1V34N@1239,3F3XZ@33958,4HG8W@91061,COG1794@1,COG1794@2 NA|NA|NA G Belongs to the aspartate glutamate racemases family PGHMIELC_00843 220668.lp_1524 1e-248 865.5 Lactobacillaceae pgaC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0007155,GO:0008150,GO:0008194,GO:0008375,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0022610,GO:0031589,GO:0042710,GO:0043708,GO:0044464,GO:0044764,GO:0051704,GO:0071944,GO:0090605 ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.1.1.2,4.D.1.1.3 GT2 Bacteria 1TR2P@1239,3F3RY@33958,4HAQN@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase PGHMIELC_00844 220668.lp_1525 2.9e-79 301.2 Lactobacillaceae Bacteria 1VG2N@1239,2E4JE@1,32ZEG@2,3F5R7@33958,4HPPN@91061 NA|NA|NA PGHMIELC_00845 220668.lp_1527 1.4e-98 365.5 Lactobacillaceae yqeG ko:K07015 ko00000 Bacteria 1V6KM@1239,3F46V@33958,4HGAV@91061,COG2179@1,COG2179@2 NA|NA|NA S HAD phosphatase, family IIIA PGHMIELC_00846 220668.lp_1528 4.5e-216 756.9 Lactobacillaceae yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 ko:K06948 ko00000,ko03009 Bacteria 1TPM2@1239,3F4JU@33958,4HAAF@91061,COG1161@1,COG1161@2 NA|NA|NA S Ribosome biogenesis GTPase YqeH PGHMIELC_00847 220668.lp_1529 1.1e-50 205.7 Lactobacillaceae yhbY GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 ko:K07574 ko00000,ko03009 Bacteria 1VEGM@1239,3F7EW@33958,4HKC7@91061,COG1534@1,COG1534@2 NA|NA|NA J RNA-binding protein PGHMIELC_00848 220668.lp_1530 1.4e-118 432.2 Lactobacillaceae nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1V3SK@1239,3F4D6@33958,4HGXK@91061,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) PGHMIELC_00849 220668.lp_1531 3.2e-115 421.0 Lactobacillaceae nadD 2.7.6.3,2.7.7.18 ko:K00950,ko:K00969,ko:K06950 ko00760,ko00790,ko01100,map00760,map00790,map01100 M00115,M00126,M00841 R00137,R03005,R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6Y1@1239,3F47C@33958,4HHRY@91061,COG1713@1,COG1713@2 NA|NA|NA H Hydrolase, HD family PGHMIELC_00850 220668.lp_1532 2.1e-58 231.5 Lactobacillaceae rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 ko:K09710 ko00000,ko03009 Bacteria 1VA2Z@1239,3F7QN@33958,4HKEJ@91061,COG0799@1,COG0799@2 NA|NA|NA J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation PGHMIELC_00851 220668.lp_1533 5.8e-140 503.4 Lactobacillaceae yqeM Bacteria 1TQUF@1239,3F4KM@33958,4HD2W@91061,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase PGHMIELC_00852 220668.lp_1534 4.9e-218 763.5 Lactobacillaceae ylbM Bacteria 1TPP2@1239,3F3QC@33958,4HAZJ@91061,COG1323@1,COG1323@2 NA|NA|NA S Belongs to the UPF0348 family PGHMIELC_00853 220668.lp_1535 1.6e-97 362.1 Lactobacillaceae yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K07040 ko00000 Bacteria 1VB08@1239,3F61Z@33958,4HME9@91061,COG1399@1,COG1399@2 NA|NA|NA S Uncharacterized ACR, COG1399 PGHMIELC_00854 220668.lp_1539 2.2e-89 335.1 Lactobacillaceae Bacteria 1VAET@1239,3F6C2@33958,4HMQ8@91061,COG3212@1,COG3212@2 NA|NA|NA S Peptidase propeptide and YPEB domain PGHMIELC_00855 220668.lp_1540 1e-168 599.4 Bacilli Bacteria 1TSGY@1239,4H9WP@91061,COG0053@1,COG0053@2 NA|NA|NA P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family PGHMIELC_00856 220668.lp_1541 3e-273 947.2 Lactobacillaceae gnd GO:0003674,GO:0003824,GO:0004616,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019520,GO:0019521,GO:0019637,GO:0019682,GO:0019693,GO:0019752,GO:0032787,GO:0034641,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046177,GO:0046395,GO:0046483,GO:0046496,GO:0046983,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072329,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 iECS88_1305.ECS88_2128,iECW_1372.ECW_m2189,iEKO11_1354.EKO11_1765,iPC815.YPO1541,iWFL_1372.ECW_m2189 Bacteria 1TP4I@1239,3F3S8@33958,4H9NC@91061,COG0362@1,COG0362@2 NA|NA|NA H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH PGHMIELC_00857 220668.lp_1543 4.2e-245 853.6 Lactobacillaceae rarA ko:K07478 ko00000 Bacteria 1TPVV@1239,3F3NB@33958,4HAIS@91061,COG2256@1,COG2256@2 NA|NA|NA L recombination factor protein RarA PGHMIELC_00858 1136177.KCA1_1314 4.3e-121 440.7 Lactobacillaceae Bacteria 1TS81@1239,3F421@33958,4H9NE@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator PGHMIELC_00859 220668.lp_1545 5.2e-306 1056.2 Lactobacillaceae arlS GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K18940 ko02020,map02020 M00716,M00717 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TPSK@1239,3F3NU@33958,4HAH5@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase PGHMIELC_00860 220668.lp_1546 5.8e-172 610.1 Lactobacillaceae 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1TSZV@1239,3F3JM@33958,4HA68@91061,COG1575@1,COG1575@2 NA|NA|NA H 1,4-dihydroxy-2-naphthoate PGHMIELC_00861 220668.lp_1548 0.0 1687.9 Lactobacillaceae sbcC ko:K03546 ko00000,ko03400 Bacteria 1TPCS@1239,3F3TE@33958,4H9Q3@91061,COG0419@1,COG0419@2 NA|NA|NA L Putative exonuclease SbcCD, C subunit PGHMIELC_00862 220668.lp_1549 4.5e-227 793.5 Lactobacillaceae sbcD ko:K03547 ko00000,ko03400 Bacteria 1TQY6@1239,3F4A9@33958,4HAKB@91061,COG0420@1,COG0420@2 NA|NA|NA L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity PGHMIELC_00863 220668.lp_1552 3.9e-99 367.5 Lactobacillaceae Bacteria 1U6DD@1239,3F7NE@33958,4IG54@91061,COG5658@1,COG5658@2 NA|NA|NA S SdpI/YhfL protein family PGHMIELC_00864 220668.lp_1553 1e-162 579.3 Lactobacillaceae yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 1TSDN@1239,3F3P3@33958,4HCC8@91061,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins PGHMIELC_00865 1136177.KCA1_1322 6.4e-44 183.0 Bacteria acyP GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036 Bacteria COG1254@1,COG1254@2 NA|NA|NA C Belongs to the acylphosphatase family PGHMIELC_00866 220668.lp_1555 7.9e-140 503.1 Lactobacillaceae spoU 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 1V3JP@1239,3F3NF@33958,4HCF5@91061,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family PGHMIELC_00867 220668.lp_1556 1.3e-93 349.0 Lactobacillaceae XK27_09705 6.1.1.14 ko:K01879,ko:K06950 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1V4QX@1239,3F64N@33958,4HHW0@91061,COG1418@1,COG1418@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. PGHMIELC_00868 1136177.KCA1_1325 7.4e-64 249.6 Lactobacillaceae yodB Bacteria 1VBI7@1239,3F7FK@33958,4HKBR@91061,COG1733@1,COG1733@2 NA|NA|NA K Transcriptional regulator, HxlR family PGHMIELC_00869 220668.lp_1558 4.9e-201 706.8 Lactobacillaceae pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPFW@1239,3F4NT@33958,4HAVN@91061,COG0016@1,COG0016@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily PGHMIELC_00870 220668.lp_1559 0.0 1598.6 Lactobacillaceae pheT GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890,ko:K06878 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_2160,iPC815.YPO2428 Bacteria 1TP98@1239,3F3V3@33958,4HAQ9@91061,COG0072@1,COG0072@2,COG0073@1,COG0073@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily PGHMIELC_00871 220668.lp_1561 6.6e-186 656.8 Lactobacillaceae mltG ko:K07082 ko00000 Bacteria 1TS48@1239,3F4IG@33958,4HAUV@91061,COG1559@1,COG1559@2 NA|NA|NA S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation PGHMIELC_00872 220668.lp_1562 2.6e-112 411.4 Lactobacillaceae udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 iSBO_1134.SBO_0893 Bacteria 1TQ4V@1239,3F3KE@33958,4HAVR@91061,COG0572@1,COG0572@2 NA|NA|NA F Cytidine monophosphokinase PGHMIELC_00873 220668.lp_1563 6.8e-81 306.6 Lactobacillaceae greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K03624 ko00000,ko03021 Bacteria 1V44S@1239,3F4ZF@33958,4HGZU@91061,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides PGHMIELC_00874 220668.lp_1564 2.3e-96 358.6 Lactobacillaceae liaI ko:K11619 ko02020,map02020 M00754 ko00000,ko00001,ko00002 Bacteria 1V7WJ@1239,3F6JJ@33958,4HR21@91061,COG4758@1,COG4758@2 NA|NA|NA S membrane PGHMIELC_00875 220668.lp_1565 4e-75 287.3 Lactobacillaceae XK27_02470 Bacteria 1VEPW@1239,3FBDY@33958,4HP5K@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain PGHMIELC_00876 220668.lp_1566 1.5e-54 218.4 Lactobacillaceae yneR Bacteria 1VEQE@1239,3F7SB@33958,4HNU2@91061,COG4841@1,COG4841@2 NA|NA|NA S Belongs to the HesB IscA family PGHMIELC_00877 220668.lp_1567 0.0 1738.4 Lactobacillaceae Bacteria 1TRR1@1239,3F49G@33958,4HBW6@91061,COG4485@1,COG4485@2 NA|NA|NA S membrane PGHMIELC_00878 220668.lp_1568 0.0 1261.9 Lactobacillaceae pbp2b 3.4.16.4 ko:K00687,ko:K05515,ko:K12553,ko:K21465 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Bacteria 1TQHY@1239,3F3KH@33958,4HAFX@91061,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein PGHMIELC_00879 1136177.KCA1_1336 1.4e-21 107.8 Lactobacillaceae rpmG ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEJ4@1239,3F828@33958,4HNIM@91061,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family PGHMIELC_00880 220668.lp_1570 6.3e-102 376.7 Lactobacillaceae ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 Bacteria 1VA91@1239,3F4KQ@33958,4HM35@91061,COG0212@1,COG0212@2 NA|NA|NA H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family PGHMIELC_00881 220668.lp_1571 1.3e-114 419.1 Lactobacillaceae gluP 3.4.21.105 ko:K19225 ko00000,ko01000,ko01002 Bacteria 1TQXT@1239,3F3WR@33958,4HCDF@91061,COG0705@1,COG0705@2 NA|NA|NA S Peptidase, S54 family PGHMIELC_00882 220668.lp_1572 1.4e-33 148.3 Lactobacillaceae yqgQ Bacteria 1VK83@1239,3F83I@33958,4HRG2@91061,COG4483@1,COG4483@2 NA|NA|NA S Bacterial protein of unknown function (DUF910) PGHMIELC_00883 220668.lp_1573 5.7e-180 636.7 Lactobacillaceae glk GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS07790 Bacteria 1TPKW@1239,3F4F0@33958,4HBAU@91061,COG1940@1,COG1940@2 NA|NA|NA G Glucokinase PGHMIELC_00884 220668.lp_1574 1.4e-110 405.6 Lactobacillaceae pepE 3.4.13.21 ko:K05995 ko00000,ko01000,ko01002 Bacteria 1V6ZV@1239,3F6J6@33958,4HJCZ@91061,COG3340@1,COG3340@2 NA|NA|NA E Belongs to the peptidase S51 family PGHMIELC_00885 220668.lp_1576 1.7e-67 261.9 Lactobacillaceae yqhL Bacteria 1VAI7@1239,3F67E@33958,4HKCE@91061,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese-like protein PGHMIELC_00886 220668.lp_1577 6.9e-23 112.5 Lactobacillaceae WQ51_02665 Bacteria 1VPEZ@1239,2C91M@1,33E1E@2,3F8C0@33958,4HRR2@91061 NA|NA|NA S Protein of unknown function (DUF3042) PGHMIELC_00887 220668.lp_1578 1.1e-138 499.2 Lactobacillaceae glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1V3W4@1239,3F4CS@33958,4HFNQ@91061,COG0584@1,COG0584@2 NA|NA|NA C phosphodiesterase PGHMIELC_00888 220668.lp_1579 1.2e-174 619.0 Lactobacillaceae miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 1TPSC@1239,3F3XS@33958,4HAVW@91061,COG0324@1,COG0324@2 NA|NA|NA F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) PGHMIELC_00889 220668.lp_1580 4.6e-64 250.4 Lactobacillaceae glnR GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141 ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1V6JE@1239,3F7RX@33958,4HKM6@91061,COG0789@1,COG0789@2 NA|NA|NA K Transcriptional regulator PGHMIELC_00890 220668.lp_1581 6.2e-265 919.5 Lactobacillaceae glnA 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 1TNZA@1239,3F41A@33958,4HACE@91061,COG0174@1,COG0174@2 NA|NA|NA E glutamine synthetase PGHMIELC_00891 220668.lp_1583 2.5e-161 574.7 Lactobacillaceae Bacteria 1V8SY@1239,2AZ1J@1,31R7P@2,3F4MX@33958,4HJRD@91061 NA|NA|NA PGHMIELC_00892 220668.lp_1584 4e-181 640.6 Lactobacillaceae Bacteria 1VK1W@1239,2F367@1,33W0S@2,3F3MT@33958,4HWH4@91061 NA|NA|NA PGHMIELC_00893 220668.lp_1585 6.2e-99 366.7 Lactobacillaceae dut Bacteria 1VGAY@1239,3F6E4@33958,4HPDT@91061,COG4508@1,COG4508@2 NA|NA|NA S Protein conserved in bacteria PGHMIELC_00894 220668.lp_1586 5.3e-56 223.4 Lactobacillaceae Bacteria 1U638@1239,2C5TQ@1,30A24@2,3F6XK@33958,4IFSJ@91061 NA|NA|NA PGHMIELC_00895 220668.lp_1587 1.7e-30 137.9 Lactobacillaceae Bacteria 1U6MJ@1239,2BRWZ@1,32KX8@2,3F85G@33958,4IGED@91061 NA|NA|NA PGHMIELC_00898 1136177.KCA1_1355 5.4e-19 99.4 Lactobacillaceae Bacteria 1U78R@1239,29PZD@1,30AXT@2,3F94K@33958,4IH3M@91061 NA|NA|NA PGHMIELC_00899 220668.lp_1591 1.8e-89 335.5 Lactobacillaceae Bacteria 1VGVA@1239,3F3TB@33958,4HPAG@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator PGHMIELC_00900 220668.lp_1592 7.5e-49 199.5 Lactobacillaceae rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9YH@1239,3F6WT@33958,4HIGK@91061,COG0261@1,COG0261@2 NA|NA|NA J This protein binds to 23S rRNA in the presence of protein L20 PGHMIELC_00901 220668.lp_1593 3.2e-53 214.2 Lactobacillaceae ysxB ko:K07584 ko00000 Bacteria 1VEQ9@1239,3F839@33958,4HNMV@91061,COG2868@1,COG2868@2 NA|NA|NA J Cysteine protease Prp PGHMIELC_00902 1136177.KCA1_1359 5.4e-46 189.9 Lactobacillaceae rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6HW@1239,3F6WU@33958,4HIMN@91061,COG0211@1,COG0211@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL27 family PGHMIELC_00903 220668.lp_1595 1.6e-194 685.3 Lactobacillaceae pepP 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 ko00000,ko01000,ko01002 Bacteria 1TQ44@1239,3F4DR@33958,4HAT7@91061,COG0006@1,COG0006@2 NA|NA|NA E Creatinase/Prolidase N-terminal domain PGHMIELC_00904 220668.lp_1596 2.2e-99 368.2 Lactobacillaceae efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 1TR8P@1239,3F422@33958,4H9YX@91061,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase PGHMIELC_00905 220668.lp_1597 3.5e-74 284.3 Lactobacillaceae yqhY ko:K10947 ko00000,ko03000 Bacteria 1V4IC@1239,3F71X@33958,4HJ7T@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function PGHMIELC_00906 220668.lp_1598 5.8e-68 263.5 Lactobacillaceae nusB ko:K03625 ko00000,ko03009,ko03021 Bacteria 1VA9B@1239,3F7KW@33958,4HKMU@91061,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons PGHMIELC_00907 220668.lp_1599 2.2e-151 541.6 Lactobacillaceae folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1P@1239,3F46A@33958,4H9Q6@91061,COG0190@1,COG0190@2 NA|NA|NA F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate PGHMIELC_00908 220668.lp_1600 1.6e-244 851.7 Lactobacillaceae xseA 3.1.11.6 ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP4E@1239,3F4RE@33958,4HAN2@91061,COG1570@1,COG1570@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides PGHMIELC_00909 220668.lp_1601 4.3e-33 146.7 Lactobacillaceae xseB 3.1.11.6 ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1VK9I@1239,3F81K@33958,4HNRB@91061,COG1722@1,COG1722@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides PGHMIELC_00910 220668.lp_1602 3e-159 567.8 Lactobacillaceae ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 ko:K00795,ko:K02523,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061,R09248 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1TPQY@1239,3F436@33958,4HA8E@91061,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family PGHMIELC_00911 220668.lp_1603 4e-150 537.3 Lactobacillaceae rrmJ 2.1.1.226,2.1.1.227 ko:K06442 ko00000,ko01000,ko03009 Bacteria 1TPE4@1239,3F45T@33958,4HAPY@91061,COG1189@1,COG1189@2 NA|NA|NA J Ribosomal RNA large subunit methyltransferase J PGHMIELC_00912 220668.lp_1604 7.4e-77 293.1 Lactobacillaceae argR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 ko:K03402 ko00000,ko03000 Bacteria 1V1R7@1239,3F71C@33958,4HFY8@91061,COG1438@1,COG1438@2 NA|NA|NA K Regulates arginine biosynthesis genes PGHMIELC_00913 220668.lp_1605 6.3e-307 1059.3 Lactobacillaceae recN GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 ko:K03631,ko:K13582 ko04112,map04112 ko00000,ko00001,ko03400 Bacteria 1TP99@1239,3F43U@33958,4H9ZR@91061,COG0497@1,COG0497@2 NA|NA|NA L May be involved in recombinational repair of damaged DNA PGHMIELC_00914 220668.lp_1607 5.7e-222 776.5 Lactobacillaceae opuCA 3.6.3.32 ko:K02000,ko:K05847 ko02010,map02010 M00208,M00209 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 iSB619.SA_RS12845,iYO844.BSU33730 Bacteria 1TPV8@1239,3F55H@33958,4H9SI@91061,COG1125@1,COG1125@2,COG2239@1,COG2239@2 NA|NA|NA E ABC transporter, ATP-binding protein PGHMIELC_00915 220668.lp_1608 1.2e-104 386.0 Lactobacillaceae opuCB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0044464,GO:0051179,GO:0051234,GO:0071705,GO:0071944 ko:K05845,ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 iYO844.BSU33720 Bacteria 1TSX8@1239,3F4EM@33958,4HC1D@91061,COG1174@1,COG1174@2 NA|NA|NA E ABC transporter permease PGHMIELC_00916 220668.lp_1609 6e-174 616.7 Lactobacillaceae opuCC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 ko:K05845,ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 iSB619.SA_RS12835 Bacteria 1TQ7D@1239,3F420@33958,4HARV@91061,COG1732@1,COG1732@2 NA|NA|NA M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) PGHMIELC_00917 220668.lp_1610 4.9e-106 390.6 Lactobacillaceae opuCD GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 iYO844.BSU33800 Bacteria 1TQ5C@1239,3F51B@33958,4HAVM@91061,COG1174@1,COG1174@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component PGHMIELC_00918 220668.lp_1611 1.7e-54 218.4 Lactobacillaceae Bacteria 1U687@1239,2DKP7@1,30A5M@2,3F7A9@33958,4IFYY@91061 NA|NA|NA PGHMIELC_00919 220668.lp_1612 3.3e-112 411.0 Lactobacillaceae gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15680 Bacteria 1TP0M@1239,3F3X9@33958,4HAYW@91061,COG0194@1,COG0194@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP PGHMIELC_00920 220668.lp_1613 2.4e-30 137.5 Lactobacillaceae rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1VK74@1239,3F81N@33958,4HNHS@91061,COG1758@1,COG1758@2 NA|NA|NA K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits PGHMIELC_00921 220668.lp_1614 4e-218 763.8 Lactobacillaceae coaBC 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPP3@1239,3F3XX@33958,4HAK8@91061,COG0452@1,COG0452@2 NA|NA|NA H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine PGHMIELC_00922 220668.lp_1615 0.0 1582.0 Lactobacillaceae priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TNYB@1239,3F3N8@33958,4H9WW@91061,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA PGHMIELC_00923 220668.lp_1616 4.2e-175 620.5 Lactobacillaceae fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000 iSB619.SA_RS06010 Bacteria 1TQ32@1239,3F4N7@33958,4HART@91061,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus PGHMIELC_00924 220668.lp_1617 1.4e-253 881.7 Lactobacillaceae sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 1TP3N@1239,3F45F@33958,4HBQ6@91061,COG0144@1,COG0144@2,COG0781@1,COG0781@2 NA|NA|NA J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA PGHMIELC_00925 220668.lp_1618 1.7e-134 485.3 Lactobacillaceae stp 3.1.3.16 ko:K20074 ko00000,ko01000,ko01009 Bacteria 1V6K5@1239,3F4UI@33958,4HCDR@91061,COG0631@1,COG0631@2 NA|NA|NA T phosphatase PGHMIELC_00926 220668.lp_1619 0.0 1255.4 Lactobacillaceae prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 1TP3F@1239,3F4G6@33958,4H9KD@91061,COG0515@1,COG0515@2,COG2815@1,COG2815@2 NA|NA|NA KLT serine threonine protein kinase PGHMIELC_00927 220668.lp_1620 1.6e-163 582.0 Lactobacillaceae rsgA 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 Bacteria 1TPSQ@1239,3F3XH@33958,4HA9W@91061,COG1162@1,COG1162@2 NA|NA|NA S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit PGHMIELC_00928 220668.lp_1621 1.2e-117 429.1 Lactobacillaceae rpe 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQK8@1239,3F4KX@33958,4H9RW@91061,COG0036@1,COG0036@2 NA|NA|NA G Belongs to the ribulose-phosphate 3-epimerase family PGHMIELC_00929 220668.lp_1622 5.8e-123 446.8 Lactobacillaceae thiN 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 R00619 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1VA0W@1239,3F4N8@33958,4HHS1@91061,COG1564@1,COG1564@2 NA|NA|NA H thiamine pyrophosphokinase PGHMIELC_00930 1136177.KCA1_1389 4.9e-27 126.3 Lactobacillaceae rpmB GO:0003674,GO:0003735,GO:0005198 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEI2@1239,3F7ZN@33958,4HNIK@91061,COG0227@1,COG0227@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL28 family PGHMIELC_00931 1136177.KCA1_1390 1.8e-57 228.4 Lactobacillaceae asp Bacteria 1V731@1239,3F72W@33958,4HIS4@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function PGHMIELC_00932 220668.lp_1626 0.0 1083.6 Lactobacillaceae yloV ko:K07030 ko00000 Bacteria 1TQMX@1239,3F3X0@33958,4HBSE@91061,COG1461@1,COG1461@2 NA|NA|NA S DAK2 domain fusion protein YloV PGHMIELC_00933 220668.lp_1627 0.0 1317.4 Lactobacillaceae recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TQ6I@1239,3F3JW@33958,4HAWN@91061,COG1200@1,COG1200@2 NA|NA|NA L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) PGHMIELC_00934 220668.lp_1628 6.7e-190 669.8 Lactobacillaceae plsX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPXS@1239,3F4N9@33958,4HA0R@91061,COG0416@1,COG0416@2 NA|NA|NA I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA PGHMIELC_00935 220668.lp_1629 1.7e-35 154.8 Lactobacillaceae acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 1VEE3@1239,3F7F4@33958,4HNQ0@91061,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis PGHMIELC_00936 220668.lp_1631 5.7e-129 466.8 Lactobacillaceae rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 1TPGC@1239,3F564@33958,4HAWU@91061,COG0571@1,COG0571@2 NA|NA|NA J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism PGHMIELC_00937 220668.lp_1632 0.0 1778.1 Lactobacillaceae smc ko:K03529 ko00000,ko03036 Bacteria 1TPJV@1239,3F478@33958,4HB89@91061,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning PGHMIELC_00938 220668.lp_1633 6.6e-170 604.0 Lactobacillaceae ftsY ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 1TPRI@1239,3F3YC@33958,4HA6A@91061,COG0552@1,COG0552@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) PGHMIELC_00939 220668.lp_1634 2.6e-58 231.1 Lactobacillaceae ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 ko:K09787 ko00000 Bacteria 1VEGP@1239,3F7FG@33958,4HKK6@91061,COG2739@1,COG2739@2 NA|NA|NA S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein PGHMIELC_00940 220668.lp_1635 1.1e-219 769.2 Lactobacillaceae ffh GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 1TP06@1239,3F40R@33958,4H9T4@91061,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY PGHMIELC_00941 1136177.KCA1_1400 2.9e-44 184.1 Lactobacillaceae rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VA0X@1239,3F6VV@33958,4HKNN@91061,COG0228@1,COG0228@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS16 family PGHMIELC_00942 220668.lp_1637 2.6e-39 167.5 Lactobacillaceae ylqC ko:K06960 ko00000 Bacteria 1VEG7@1239,3F829@33958,4HNX0@91061,COG1837@1,COG1837@2 NA|NA|NA S Belongs to the UPF0109 family PGHMIELC_00943 220668.lp_1638 8.2e-96 356.3 Lactobacillaceae rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 ko:K02860 ko00000,ko03009 Bacteria 1V6HD@1239,3F74P@33958,4HH3H@91061,COG0806@1,COG0806@2 NA|NA|NA J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes PGHMIELC_00944 220668.lp_1639 3.4e-140 504.2 Lactobacillaceae trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1TPBV@1239,3F3NP@33958,4HBFV@91061,COG0336@1,COG0336@2 NA|NA|NA J Belongs to the RNA methyltransferase TrmD family PGHMIELC_00945 220668.lp_1640 1.9e-59 235.0 Lactobacillaceae rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6FT@1239,3F6K4@33958,4HIK3@91061,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site PGHMIELC_00946 220668.lp_1642 1.4e-50 205.3 Lactobacillaceae Bacteria 1W0B2@1239,2FI7A@1,349ZW@2,3F7DI@33958,4HY9R@91061 NA|NA|NA PGHMIELC_00947 220668.lp_1643 0.0 3452.5 Lactobacillaceae pelX GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0044877,GO:0051704,GO:0070051,GO:0098630,GO:0098743 ko:K14194,ko:K14201,ko:K20276 ko02024,ko05150,map02024,map05150 ko00000,ko00001 Bacteria 1VSP5@1239,3F4FY@33958,4HUK1@91061,COG3266@1,COG3266@2,COG5295@1,COG5295@2 NA|NA|NA UW LPXTG-motif cell wall anchor domain protein PGHMIELC_00948 220668.lp_1645 1.4e-86 325.5 Lactobacillaceae Bacteria 1VFYC@1239,2DPIQ@1,3328X@2,3F6VH@33958,4HNHQ@91061 NA|NA|NA PGHMIELC_00949 220668.lp_1648 2.3e-139 501.5 Lactobacillaceae ecsA_2 ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQIH@1239,3FC35@33958,4HCEU@91061,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system PGHMIELC_00950 220668.lp_1649 8.1e-272 942.6 Lactobacillaceae XK27_00765 ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TSZA@1239,28MBB@1,2ZAPV@2,3F4FX@33958,4HDKH@91061 NA|NA|NA PGHMIELC_00951 220668.lp_1652 2.9e-268 930.6 Lactobacillaceae trpE GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQAP@1239,3F4RG@33958,4HB31@91061,COG0147@1,COG0147@2 NA|NA|NA EH Anthranilate synthase component I, N terminal region PGHMIELC_00952 220668.lp_1653 1.5e-104 385.6 Lactobacillaceae trpG 2.4.2.18,2.6.1.85,4.1.3.27 ko:K01658,ko:K01664,ko:K13497 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01073,R01716 RC00010,RC00440,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 1TT9R@1239,3F4C7@33958,4H9XP@91061,COG0512@1,COG0512@2 NA|NA|NA EH Peptidase C26 PGHMIELC_00953 220668.lp_1654 1.3e-166 592.4 Lactobacillaceae trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP8U@1239,3F50X@33958,4H9KQ@91061,COG0547@1,COG0547@2 NA|NA|NA F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) PGHMIELC_00954 220668.lp_1655 2.4e-123 448.4 Lactobacillaceae trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K01817,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR94@1239,3F5AK@33958,4HDZQ@91061,COG0134@1,COG0134@2 NA|NA|NA E Belongs to the TrpC family PGHMIELC_00955 220668.lp_1656 2.2e-108 398.3 Lactobacillaceae trpF GO:0000162,GO:0003674,GO:0003824,GO:0004425,GO:0004640,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48,4.2.1.160,4.2.1.20,5.3.1.24 ko:K01696,ko:K01817,ko:K13498,ko:K22100 ko00260,ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map00790,map01100,map01110,map01130,map01230 M00023,M00840 R00674,R02340,R02722,R03508,R03509,R11072 RC00209,RC00210,RC00700,RC00701,RC00944,RC00945,RC02868,RC03343 ko00000,ko00001,ko00002,ko01000 iJN678.trpF,iPC815.YPO2205,iSBO_1134.SBO_1804,iSDY_1059.SDY_1330 Bacteria 1V6Y0@1239,3F4B6@33958,4HN68@91061,COG0135@1,COG0135@2 NA|NA|NA E Belongs to the TrpF family PGHMIELC_00956 220668.lp_1657 3.9e-226 790.4 Lactobacillaceae trpB 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPI3@1239,3F4DT@33958,4H9WC@91061,COG0133@1,COG0133@2 NA|NA|NA E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine PGHMIELC_00957 220668.lp_1658 8.7e-142 509.6 Lactobacillaceae trpA 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPXA@1239,3F50S@33958,4HFQ8@91061,COG0159@1,COG0159@2 NA|NA|NA E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate PGHMIELC_00958 220668.lp_1659 1.5e-97 362.1 Lactobacillaceae entB 3.5.1.19 ko:K08281 ko00760,ko01100,map00760,map01100 R01268 RC00100 ko00000,ko00001,ko01000 Bacteria 1V347@1239,3F716@33958,4HGFM@91061,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family PGHMIELC_00959 220668.lp_1660 2.6e-177 627.9 Lactobacillaceae 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 1UYWR@1239,3F5V1@33958,4HDC6@91061,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase PGHMIELC_00960 220668.lp_1662 1.6e-67 262.3 Lactobacillaceae ybbJ Bacteria 1UIVT@1239,3F7X6@33958,4ISTU@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) family PGHMIELC_00961 220668.lp_1663 4.4e-217 760.4 Lactobacillaceae Bacteria 1TS2B@1239,3F5R6@33958,4HCID@91061,COG0786@1,COG0786@2 NA|NA|NA E glutamate:sodium symporter activity PGHMIELC_00962 220668.lp_1664 2.5e-214 751.1 Lactobacillaceae 3.5.1.47 ko:K01436,ko:K05823,ko:K21613 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPD7@1239,3FC42@33958,4H9WQ@91061,COG1473@1,COG1473@2 NA|NA|NA E Peptidase family M20/M25/M40 PGHMIELC_00963 220668.lp_1665 5.1e-198 696.8 Lactobacillaceae adhB 1.1.1.1,1.1.1.14 ko:K00001,ko:K00008 ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 M00014 R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPIW@1239,3F42F@33958,4HB2G@91061,COG1063@1,COG1063@2 NA|NA|NA E alcohol dehydrogenase PGHMIELC_00964 220668.lp_1667 2.7e-58 231.1 Lactobacillaceae Bacteria 1U68C@1239,2A1GT@1,30PQE@2,3F7AG@33958,4IFZ2@91061 NA|NA|NA S Protein of unknown function (DUF1648) PGHMIELC_00965 220668.lp_1668 3e-145 521.2 Lactobacillaceae Bacteria 1TQDY@1239,3FBSM@33958,4HBS5@91061,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family PGHMIELC_00966 220668.lp_1669 3.8e-179 634.0 Lactobacillaceae yneE Bacteria 1UI1Z@1239,3F4Q1@33958,4HC2Y@91061,COG2207@1,COG2207@2 NA|NA|NA K Transcriptional regulator PGHMIELC_00967 220668.lp_1670 2.3e-75 288.1 Lactobacillaceae fabZ 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 1V3UN@1239,3FCD6@33958,4HHYD@91061,COG0764@1,COG0764@2 NA|NA|NA I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs PGHMIELC_00968 220668.lp_1671 7.7e-180 636.3 Lactobacillaceae fabH 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TP0K@1239,3F3XP@33958,4HATK@91061,COG0332@1,COG0332@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids PGHMIELC_00969 220668.lp_1672 3.8e-35 153.7 Lactobacillaceae acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 1VGIY@1239,3F7ZJ@33958,4HP0V@91061,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis PGHMIELC_00970 220668.lp_1673 2e-169 601.7 Lactobacillaceae fabD 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPB7@1239,3F3W9@33958,4HBCU@91061,COG0331@1,COG0331@2 NA|NA|NA I Malonyl CoA-acyl carrier protein transacylase PGHMIELC_00971 220668.lp_1674 1.2e-126 459.1 Lactobacillaceae Bacteria 1TP76@1239,3F4RI@33958,4HAA6@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase PGHMIELC_00972 220668.lp_1675 3.6e-227 793.9 Lactobacillaceae fabF 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPA7@1239,3F51H@33958,4H9SD@91061,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP PGHMIELC_00973 220668.lp_1676 5.9e-74 283.5 Lactobacillaceae accB 2.3.1.12,4.1.1.3 ko:K00627,ko:K01571,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00217,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 Bacteria 1VAB7@1239,3F7M1@33958,4HKCS@91061,COG0511@1,COG0511@2 NA|NA|NA I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA PGHMIELC_00974 220668.lp_1677 1.2e-70 272.3 Lactobacillaceae fabZ 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 1VXBZ@1239,3F6TF@33958,4HXVK@91061,COG0764@1,COG0764@2 NA|NA|NA I FabA-like domain PGHMIELC_00975 220668.lp_1678 2.1e-260 904.4 Lactobacillaceae accC GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iSF_1195.SF3294 Bacteria 1TP16@1239,3F3PT@33958,4HARK@91061,COG0439@1,COG0439@2 NA|NA|NA I Acetyl-CoA carboxylase biotin carboxylase subunit PGHMIELC_00976 220668.lp_1679 3.5e-157 560.8 Lactobacillaceae accD 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4U@1239,3F3T6@33958,4HAI7@91061,COG0777@1,COG0777@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA PGHMIELC_00977 220668.lp_1680 8.8e-139 499.6 Lactobacillaceae accA 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHNS@1239,3F496@33958,4HA4C@91061,COG0825@1,COG0825@2 NA|NA|NA I alpha subunit PGHMIELC_00978 220668.lp_1681 1.3e-134 485.7 Lactobacillaceae fabI GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPVD@1239,3F4AQ@33958,4H9YN@91061,COG0623@1,COG0623@2 NA|NA|NA I Enoyl- acyl-carrier-protein reductase NADH PGHMIELC_00979 220668.lp_1682 2.4e-98 364.8 Lactobacillaceae 2.7.8.7 ko:K00997,ko:K06133 ko00770,map00770 R01625 RC00002 ko00000,ko00001,ko01000 Bacteria 1VK9G@1239,3F71W@33958,4HRUX@91061,COG2091@1,COG2091@2 NA|NA|NA H Belongs to the P-Pant transferase superfamily PGHMIELC_00980 220668.lp_1684 1.3e-123 449.1 Lactobacillaceae ko:K07150 ko00000 Bacteria 1TQWV@1239,3FB61@33958,4IQYF@91061,COG1811@1,COG1811@2 NA|NA|NA S Protein of unknown function (DUF554) PGHMIELC_00981 220668.lp_1685 2.7e-160 571.2 Lactobacillaceae ko:K09681 ko00000,ko03000 Bacteria 1TQ6Y@1239,3F4CY@33958,4HWQQ@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain PGHMIELC_00982 220668.lp_1686 4.6e-88 330.5 Lactobacillaceae ykhA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 3.1.2.20 ko:K01073 ko00000,ko01000 Bacteria 1V3S2@1239,3F6A3@33958,4HJ0Z@91061,COG1607@1,COG1607@2 NA|NA|NA I Thioesterase superfamily PGHMIELC_00983 220668.lp_1687 1.7e-193 681.8 Lactobacillaceae rsgA 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 Bacteria 1TP8Q@1239,3F5GW@33958,4H9PJ@91061,COG1162@1,COG1162@2 NA|NA|NA S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit PGHMIELC_00984 220668.lp_1688 6.8e-93 346.7 Lactobacillaceae Bacteria 1VHWM@1239,3F6Q3@33958,4IFMJ@91061,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator PGHMIELC_00985 220668.lp_1689 1.2e-302 1045.0 Lactobacillaceae norB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 ko:K08170 M00702 ko00000,ko00002,ko01504,ko02000 2.A.1.3.23,2.A.1.3.59 Bacteria 1TPV3@1239,3F5DE@33958,4HCJN@91061,COG0477@1,COG0477@2,COG2211@1,COG2211@2 NA|NA|NA EGP Major Facilitator PGHMIELC_00986 220668.lp_1690 4.4e-139 500.7 Lactobacillaceae f42a Bacteria 1TRN5@1239,3F4ES@33958,4HA6G@91061,COG0330@1,COG0330@2 NA|NA|NA O Band 7 protein PGHMIELC_00987 913848.AELK01000066_gene1236 2.2e-39 169.1 Lactobacillaceae Bacteria 1TTJI@1239,3F5DJ@33958,4HEI7@91061,COG0582@1,COG0582@2 NA|NA|NA L Pfam:Integrase_AP2 PGHMIELC_00988 768486.EHR_09760 1.2e-25 122.9 Enterococcaceae Bacteria 1TTJI@1239,4B1EA@81852,4HEI7@91061,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase, N-terminal SAM-like domain PGHMIELC_00991 1423734.JCM14202_3583 4e-09 67.0 Lactobacillaceae Bacteria 1U6Z9@1239,2DKT3@1,30AQA@2,3F8RG@33958,4IGTI@91061 NA|NA|NA PGHMIELC_00993 220668.lp_1694 1.1e-53 215.7 Lactobacillaceae Bacteria 1U76E@1239,29PKS@1,30C1A@2,3F919@33958,4IH15@91061 NA|NA|NA PGHMIELC_00994 220668.lp_1695 1.6e-28 131.3 Lactobacillaceae Bacteria 1U773@1239,29EYP@1,301WG@2,3F925@33958,4IH1X@91061 NA|NA|NA PGHMIELC_00995 220668.lp_1696 2.5e-209 734.6 Lactobacillaceae cfa 2.1.1.317,2.1.1.79 ko:K00574,ko:K20238 ko00000,ko01000 Bacteria 1TSG4@1239,3F3PA@33958,4HDKI@91061,COG2230@1,COG2230@2 NA|NA|NA M cyclopropane-fatty-acyl-phospholipid synthase PGHMIELC_00996 220668.lp_1697 4.5e-114 417.2 Lactobacillaceae 1.14.99.53 ko:K21713 ko00000,ko01000 AA10 Bacteria 1V9FX@1239,3F5UI@33958,4HK49@91061,COG3397@1,COG3397@2 NA|NA|NA S Lytic polysaccharide mono-oxygenase, cellulose-degrading PGHMIELC_00997 220668.lp_1698 5.8e-48 196.4 Lactobacillaceae ycnE GO:0003674,GO:0003824 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 1VG4T@1239,3F7H6@33958,4HPNQ@91061,COG1359@1,COG1359@2 NA|NA|NA S Antibiotic biosynthesis monooxygenase PGHMIELC_00998 220668.lp_1699 7.9e-41 172.6 Lactobacillaceae Bacteria 1W1QU@1239,2CH90@1,2ZP4M@2,3F71E@33958,4I01G@91061 NA|NA|NA PGHMIELC_00999 220668.lp_1700 4.3e-67 260.8 Lactobacillaceae tspO ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 9.A.24 Bacteria 1V896@1239,3F6ED@33958,4HK1B@91061,COG3476@1,COG3476@2 NA|NA|NA T TspO/MBR family PGHMIELC_01000 220668.lp_1701 1.4e-75 288.9 Lactobacillaceae uspA ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1U425@1239,3F6XU@33958,4I3ZI@91061,COG0589@1,COG0589@2 NA|NA|NA T Belongs to the universal stress protein A family PGHMIELC_01001 220668.lp_1702 8e-66 256.1 Lactobacillaceae Bacteria 1V90R@1239,3F6JH@33958,4HWPI@91061,COG3152@1,COG3152@2 NA|NA|NA S Protein of unknown function (DUF805) PGHMIELC_01002 220668.lp_1703 1.8e-164 585.1 Lactobacillaceae yegS GO:0001727,GO:0003674,GO:0003824,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0030258,GO:0044237,GO:0044238,GO:0044255,GO:0046834,GO:0071704 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 R02240 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1V4PN@1239,3F3Z6@33958,4HHJP@91061,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain PGHMIELC_01003 220668.lp_1704 1.3e-35 155.2 Lactobacillaceae Bacteria 1U6P5@1239,2BU5G@1,32PEE@2,3F88H@33958,4IGG5@91061 NA|NA|NA PGHMIELC_01004 220668.lp_1705 3.1e-14 83.2 Lactobacillaceae Bacteria 1U78C@1239,2BHKH@1,32BP3@2,3F93Y@33958,4IH38@91061 NA|NA|NA PGHMIELC_01005 220668.lp_1706 6.5e-41 172.9 Lactobacillaceae Bacteria 1U6BD@1239,3F7IA@33958,4IG2Z@91061,COG2261@1,COG2261@2 NA|NA|NA S transglycosylase associated protein PGHMIELC_01006 220668.lp_1708 4.8e-29 133.3 Lactobacillaceae Bacteria 1VZVB@1239,3F7E6@33958,4HYP0@91061,COG3237@1,COG3237@2 NA|NA|NA S CsbD-like PGHMIELC_01007 220668.lp_1709 9.4e-40 169.1 Lactobacillaceae Bacteria 1U6EF@1239,2CH91@1,30AAP@2,3F7QH@33958,4IG67@91061 NA|NA|NA PGHMIELC_01008 220668.lp_1711 8.6e-281 972.2 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase PGHMIELC_01009 1136177.KCA1_1460 5.1e-27 126.3 Lactobacillaceae dmpI GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 Bacteria 1VKD5@1239,3F83T@33958,4HRBS@91061,COG1942@1,COG1942@2 NA|NA|NA G Belongs to the 4-oxalocrotonate tautomerase family PGHMIELC_01010 220668.lp_1713 5.7e-255 886.3 Lactobacillaceae lysA 4.1.1.19,4.1.1.20 ko:K01585,ko:K01586 ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map01100,map01110,map01120,map01130,map01230 M00016,M00133,M00525,M00526,M00527 R00451,R00566 RC00299 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS18870 Bacteria 1TPE9@1239,3F3VJ@33958,4H9XW@91061,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine PGHMIELC_01011 220668.lp_1715 1.8e-170 605.1 Lactobacillaceae 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1VW8B@1239,3F50H@33958,4HW7F@91061,COG1575@1,COG1575@2 NA|NA|NA H UbiA prenyltransferase family PGHMIELC_01012 220668.lp_1716 1.4e-136 492.3 Lactobacillaceae potC 2.1.1.172,2.1.1.80,3.1.1.61 ko:K00564,ko:K02026,ko:K10716,ko:K11070,ko:K13924,ko:K14393 ko02010,ko02020,ko02030,map02010,map02020,map02030 M00207,M00299,M00506 R07234 RC00003 ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035,ko03009 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6,2.A.21.7,3.A.1.1,3.A.1.11.1 Bacteria 1UI61@1239,3FBSN@33958,4ISEY@91061,COG1340@1,COG1340@2 NA|NA|NA U Ion channel PGHMIELC_01013 220668.lp_1717 3.9e-50 203.8 Lactobacillaceae Bacteria 1U6WR@1239,2CH92@1,30ANJ@2,3F8MV@33958,4IGQX@91061 NA|NA|NA PGHMIELC_01014 220668.lp_1718 1.3e-42 178.7 Lactobacillaceae Bacteria 1U8DV@1239,29QP8@1,30BNW@2,3FAVI@33958,4IIBS@91061 NA|NA|NA PGHMIELC_01015 220668.lp_1721 8.7e-259 899.0 Lactobacillaceae gabT 2.6.1.19,5.1.1.21 ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1VS6F@1239,3F569@33958,4H9M7@91061,COG0160@1,COG0160@2 NA|NA|NA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family PGHMIELC_01016 220668.lp_1722 1.4e-265 921.8 Lactobacillaceae yfnA ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3F3QY@33958,4HA66@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid PGHMIELC_01017 220668.lp_1723 1.2e-149 535.8 Lactobacillaceae yitU 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TREF@1239,3F47B@33958,4H9Y9@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase PGHMIELC_01018 220668.lp_1724 1.6e-268 931.4 Lactobacillaceae rsmF GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176,2.1.1.178 ko:K03500,ko:K11392 ko00000,ko01000,ko03009 Bacteria 1TPGQ@1239,3F492@33958,4HCHQ@91061,COG0144@1,COG0144@2,COG3270@1,COG3270@2 NA|NA|NA J NOL1 NOP2 sun family protein PGHMIELC_01019 220668.lp_1726 2.2e-85 322.4 Lactobacillaceae Bacteria 1W05T@1239,2DR8S@1,33AQ2@2,3F63G@33958,4HZ0I@91061 NA|NA|NA S Domain of unknown function (DUF4767) PGHMIELC_01020 220668.lp_1729 2.5e-250 870.9 Lactobacillaceae malT ko:K16211 ko00000,ko02000 2.A.2.6 Bacteria 1TRP7@1239,3F3YZ@33958,4HCUK@91061,COG2211@1,COG2211@2 NA|NA|NA G Major Facilitator PGHMIELC_01021 220668.lp_1730 0.0 1488.0 Lactobacillaceae mapA 2.4.1.8 ko:K00691 ko00500,ko01100,map00500,map01100 R01555 RC00049 ko00000,ko00001,ko01000 GH65 Bacteria 1TQMB@1239,3F3PG@33958,4HAVB@91061,COG1554@1,COG1554@2 NA|NA|NA G hydrolase, family 65, central catalytic PGHMIELC_01022 220668.lp_1731 2.1e-193 681.4 Lactobacillaceae galM 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 1V5UK@1239,3FC7G@33958,4HTRY@91061,COG2017@1,COG2017@2 NA|NA|NA G Catalyzes the interconversion of alpha and beta anomers of maltose PGHMIELC_01023 220668.lp_1732 6.2e-196 689.9 Lactobacillaceae fni 1.1.1.88,5.3.3.2 ko:K00054,ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123,R02081 RC00004,RC00455,RC00644 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQZ3@1239,3F3UY@33958,4HAMV@91061,COG1304@1,COG1304@2 NA|NA|NA C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) PGHMIELC_01024 220668.lp_1733 7.6e-205 719.5 Lactobacillaceae mvaK2 2.7.1.36,2.7.1.43,2.7.4.2 ko:K00869,ko:K00938,ko:K16190 ko00040,ko00053,ko00520,ko00900,ko01100,ko01110,ko01130,ko04146,map00040,map00053,map00520,map00900,map01100,map01110,map01130,map04146 M00014,M00095 R01476,R02245,R03245 RC00002,RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPKP@1239,3F3RZ@33958,4HC93@91061,COG1577@1,COG1577@2 NA|NA|NA I phosphomevalonate kinase PGHMIELC_01025 220668.lp_1734 7.4e-175 619.8 Lactobacillaceae mvaD 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQXR@1239,3F4B5@33958,4HAM6@91061,COG3407@1,COG3407@2 NA|NA|NA I diphosphomevalonate decarboxylase PGHMIELC_01026 220668.lp_1735 4e-170 604.0 Lactobacillaceae mvk 1.1.1.88,2.3.3.10,2.7.1.36 ko:K00054,ko:K00869,ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,ko04146,map00072,map00280,map00650,map00900,map01100,map01110,map01130,map04146 M00088,M00095 R01978,R02081,R02245 RC00002,RC00004,RC00017,RC00503,RC00644 ko00000,ko00001,ko00002,ko01000 Bacteria 1TT5C@1239,3F3TW@33958,4HAQQ@91061,COG1577@1,COG1577@2 NA|NA|NA I mevalonate kinase PGHMIELC_01027 220668.lp_1737 0.0 1830.8 Lactobacillaceae dinG GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.6.4.12 ko:K02342,ko:K03722 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TQHQ@1239,3F4KA@33958,4HB2Y@91061,COG0847@1,COG0847@2,COG1199@1,COG1199@2 NA|NA|NA L helicase involved in DNA repair and perhaps also replication PGHMIELC_01028 220668.lp_1738 2.1e-72 278.5 Bacteria ypmB Bacteria COG5353@1,COG5353@2 NA|NA|NA S protein conserved in bacteria PGHMIELC_01029 220668.lp_1739 1.1e-225 788.9 Lactobacillaceae aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 iHN637.CLJU_RS06550 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase PGHMIELC_01030 220668.lp_1740 5.4e-258 896.3 Lactobacillaceae asnS GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP38@1239,3F4EK@33958,4H9YH@91061,COG0017@1,COG0017@2 NA|NA|NA J Asparaginyl-tRNA synthetase PGHMIELC_01031 220668.lp_1741 1.3e-128 465.7 Lactobacillaceae dnaD ko:K02086 ko00000 Bacteria 1V283@1239,3FC5X@33958,4HFP3@91061,COG3935@1,COG3935@2 NA|NA|NA L Replication initiation and membrane attachment PGHMIELC_01033 220668.lp_1744 4.1e-187 660.6 Lactobacillaceae metN ko:K02071 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TPPN@1239,3F3U5@33958,4H9VX@91061,COG1135@1,COG1135@2 NA|NA|NA P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system PGHMIELC_01034 220668.lp_1745 2e-99 368.6 Lactobacillaceae metI ko:K02069,ko:K02072 ko02010,map02010 M00211,M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24,9.B.25.1 Bacteria 1TRSY@1239,3F48A@33958,4HBEV@91061,COG2011@1,COG2011@2 NA|NA|NA P ABC transporter permease PGHMIELC_01035 220668.lp_1746 8e-157 559.7 Lactobacillaceae metQ_4 ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1V0Z6@1239,3FC6K@33958,4HBBW@91061,COG1464@1,COG1464@2 NA|NA|NA P Belongs to the nlpA lipoprotein family PGHMIELC_01036 220668.lp_1747 4.4e-83 313.9 Lactobacillaceae uspA ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1U426@1239,3F5PR@33958,4IF5I@91061,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein family PGHMIELC_01037 220668.lp_1748 3.5e-302 1043.5 Lactobacillaceae ftpA ko:K02011 ko02010,map02010 M00190 ko00000,ko00001,ko00002,ko02000 3.A.1.10 Bacteria 1TPMX@1239,3F5YV@33958,4HC5I@91061,COG1178@1,COG1178@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component PGHMIELC_01038 220668.lp_1749 6.4e-182 643.3 Lactobacillaceae ftpB ko:K02012 ko02010,map02010 M00190 ko00000,ko00001,ko00002,ko02000 3.A.1.10 Bacteria 1TQC3@1239,3F5CD@33958,4HBE1@91061,COG1840@1,COG1840@2 NA|NA|NA P Bacterial extracellular solute-binding protein PGHMIELC_01039 220668.lp_1750 8.2e-179 632.9 Lactobacillaceae phnT 3.6.3.30 ko:K02010 ko02010,map02010 M00190 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 Bacteria 1TPW2@1239,3F55Y@33958,4HD3J@91061,COG3842@1,COG3842@2 NA|NA|NA P ATPases associated with a variety of cellular activities PGHMIELC_01040 220668.lp_1751 0.0 1293.5 Lactobacillaceae ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366,ko:K12555,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1TPM5@1239,3F424@33958,4H9SA@91061,COG0744@1,COG0744@2 NA|NA|NA M penicillin-binding protein 1A PGHMIELC_01041 220668.lp_1752 7.6e-117 426.4 Lactobacillaceae recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03700 ko00000,ko03400 Bacteria 1V3S4@1239,3F4DG@33958,4HGZ7@91061,COG3331@1,COG3331@2 NA|NA|NA L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation PGHMIELC_01042 220668.lp_1753 8.3e-110 402.9 Lactobacillaceae ypsA Bacteria 1V6SM@1239,3F4MR@33958,4HJGM@91061,COG4474@1,COG4474@2 NA|NA|NA S Belongs to the UPF0398 family PGHMIELC_01043 1136177.KCA1_1523 3.2e-56 224.2 Lactobacillaceae gpsB ko:K04074 ko00000,ko03036 Bacteria 1VEQ4@1239,3F6VZ@33958,4HNP1@91061,COG3599@1,COG3599@2 NA|NA|NA D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation PGHMIELC_01045 220668.lp_1756 4e-223 780.4 Lactobacillaceae rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016423,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 ko:K07444,ko:K12297 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1TP0X@1239,3F3NZ@33958,4HBKY@91061,COG0116@1,COG0116@2 NA|NA|NA L Belongs to the methyltransferase superfamily PGHMIELC_01047 220668.lp_1760 8e-145 519.6 Lactobacillaceae yjfP GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0034338,GO:0052689 ko:K06889 ko00000 Bacteria 1TTC0@1239,3F5IB@33958,4HBCG@91061,COG1073@1,COG1073@2 NA|NA|NA S COG1073 Hydrolases of the alpha beta superfamily PGHMIELC_01048 220668.lp_1762 4.4e-73 280.4 Lactobacillaceae ko:K06893,ko:K15236 ko00361,ko01100,ko01120,map00361,map01100,map01120 R05386,R05387 RC01353 ko00000,ko00001,ko01000 Bacteria 1V76Z@1239,3F8AB@33958,4HP66@91061,COG3631@1,COG3631@2 NA|NA|NA S SnoaL-like domain PGHMIELC_01049 220668.lp_1763 2.4e-200 704.5 Bacilli Bacteria 1VVRP@1239,4HVYS@91061,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase, group 2 family protein PGHMIELC_01050 220668.lp_1764 2.5e-208 731.1 Lactobacillaceae mccF Bacteria 1TRBB@1239,3F3NK@33958,4HDUZ@91061,COG1619@1,COG1619@2 NA|NA|NA V LD-carboxypeptidase PGHMIELC_01051 60520.HR47_12515 1.4e-78 298.9 Lactobacillaceae Bacteria 1UI4U@1239,3FBSP@33958,4ISEZ@91061,COG0454@1,COG0454@2 NA|NA|NA K Acetyltransferase (GNAT) domain PGHMIELC_01052 220668.lp_1767 1.5e-239 835.1 Lactobacillaceae ko:K07273 ko00000 Bacteria 1V2YH@1239,3F4G3@33958,4HKBF@91061,COG3757@1,COG3757@2 NA|NA|NA M hydrolase, family 25 PGHMIELC_01053 220668.lp_1768 1.6e-182 645.2 Lactobacillaceae mccF GO:0008150,GO:0008152,GO:0009404,GO:0009987,GO:0019748,GO:0030153,GO:0044237 3.4.17.13 ko:K01297 ko00000,ko01000,ko01002,ko01011 Bacteria 1TRBB@1239,3F3NK@33958,4HDUZ@91061,COG1619@1,COG1619@2 NA|NA|NA V LD-carboxypeptidase PGHMIELC_01054 220668.lp_1770 7.8e-124 449.9 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1U52G@1239,2BQSR@1,32JPE@2,3F46K@33958,4IETW@91061 NA|NA|NA PGHMIELC_01055 220668.lp_1771 6.6e-122 443.4 Lactobacillaceae 3.6.3.35 ko:K01990,ko:K02049,ko:K02074,ko:K03546,ko:K09817,ko:K19973 ko02010,map02010 M00188,M00242,M00244,M00254,M00792 ko00000,ko00001,ko00002,ko01000,ko02000,ko03400 3.A.1,3.A.1.15,3.A.1.15.15,3.A.1.15.3,3.A.1.15.5,3.A.1.16,3.A.1.17 Bacteria 1U52X@1239,3F47U@33958,4IEUB@91061,COG1121@1,COG1121@2 NA|NA|NA P ATPases associated with a variety of cellular activities PGHMIELC_01056 220668.lp_1773 3.5e-194 684.1 Lactobacillaceae Bacteria 1U5GV@1239,2BKEI@1,32EV9@2,3F5WP@33958,4IF7K@91061 NA|NA|NA PGHMIELC_01057 220668.lp_1774 4.5e-146 523.9 Bacteria Bacteria COG0596@1,COG0596@2 NA|NA|NA S hydrolase activity, acting on ester bonds PGHMIELC_01058 220668.lp_1776 1.1e-211 742.3 Lactobacillaceae yurR GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 1.4.5.1 ko:K00285 ko00360,map00360 R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 Bacteria 1TQTF@1239,3F410@33958,4HA0F@91061,COG0665@1,COG0665@2 NA|NA|NA E FAD dependent oxidoreductase PGHMIELC_01059 220668.lp_1777 2.2e-66 258.1 Lactobacillaceae rnhA 3.1.26.4 ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1VH2B@1239,3F7JC@33958,4HIY9@91061,COG0328@1,COG0328@2 NA|NA|NA L Ribonuclease HI PGHMIELC_01060 220668.lp_1778 3.3e-62 244.2 Lactobacillaceae esbA Bacteria 1W31C@1239,2BZWG@1,2ZPAS@2,3F6SQ@33958,4I09H@91061 NA|NA|NA S Family of unknown function (DUF5322) PGHMIELC_01061 220668.lp_1779 4.1e-295 1020.0 Lactobacillaceae fhs GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP6N@1239,3F3U6@33958,4HA2X@91061,COG2759@1,COG2759@2 NA|NA|NA F Belongs to the formate--tetrahydrofolate ligase family PGHMIELC_01062 220668.lp_1780 4.4e-74 283.9 Lactobacillaceae lspA 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1VA9R@1239,3F66R@33958,4HIR4@91061,COG0597@1,COG0597@2 NA|NA|NA MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins PGHMIELC_01063 220668.lp_1781 2e-174 618.2 Lactobacillaceae rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1TPCM@1239,3F3P6@33958,4HBG2@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil PGHMIELC_01064 220668.lp_1782 3.3e-89 334.3 Lactobacillaceae pyrR 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000,ko03000 Bacteria 1V3GV@1239,3F4SR@33958,4HGYE@91061,COG2065@1,COG2065@2 NA|NA|NA F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant PGHMIELC_01065 220668.lp_1783 8.1e-207 726.1 Lactobacillaceae carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383,iYO844.BSU15510 Bacteria 1VTN5@1239,3FC4C@33958,4HT8S@91061,COG0505@1,COG0505@2 NA|NA|NA F Belongs to the CarA family PGHMIELC_01066 220668.lp_1784 0.0 1657.1 Lactobacillaceae carB 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPID@1239,3F3MD@33958,4HAEY@91061,COG0458@1,COG0458@2 NA|NA|NA F Carbamoyl-phosphate synthase PGHMIELC_01067 60520.HR47_12600 8.8e-288 995.7 Lactobacillaceae Bacteria 1UZCF@1239,3F48H@33958,4HDPY@91061,COG4485@1,COG4485@2 NA|NA|NA S Bacterial membrane protein, YfhO PGHMIELC_01068 220668.lp_1785 6.4e-113 413.3 Lactobacillaceae pgm5 Bacteria 1UXY8@1239,3F4JB@33958,4HFD9@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family PGHMIELC_01069 220668.lp_1786 3.1e-71 274.2 Lactobacillaceae frataxin ko:K05937 ko00000 Bacteria 1V6QT@1239,3F79K@33958,4HIUI@91061,COG5646@1,COG5646@2 NA|NA|NA S Domain of unknown function (DU1801) PGHMIELC_01072 220668.lp_1787 1.7e-130 471.9 Lactobacillaceae cat 2.3.1.28 ko:K19271 br01600,ko00000,ko01000,ko01504 Bacteria 1UY81@1239,3F60A@33958,4HF75@91061,COG4845@1,COG4845@2 NA|NA|NA V Chloramphenicol acetyltransferase PGHMIELC_01073 220668.lp_1788 1.2e-69 268.9 Lactobacillaceae Bacteria 1V6T5@1239,3F6JC@33958,4HPJA@91061,COG3860@1,COG3860@2 NA|NA|NA S LuxR family transcriptional regulator PGHMIELC_01074 220668.lp_1789 2.9e-136 491.1 Lactobacillaceae Bacteria 1TPHH@1239,3F56B@33958,4HCHE@91061,COG3860@1,COG3860@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2087) PGHMIELC_01075 220668.lp_1790 9.7e-91 339.3 Lactobacillaceae 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1VDM3@1239,3F6RN@33958,4HMI0@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain PGHMIELC_01076 220668.lp_1791 2.7e-163 581.3 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TP4J@1239,3F3YW@33958,4HBGH@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter, ATP-binding protein PGHMIELC_01077 220668.lp_1792 3.5e-132 477.6 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1GX@1239,3F52P@33958,4HG2P@91061,COG1277@1,COG1277@2 NA|NA|NA S ABC-2 family transporter protein PGHMIELC_01078 220668.lp_1793 0.0 1119.8 Lactobacillaceae FbpA ko:K12341 ko03070,map03070 ko00000,ko00001,ko02044 1.B.40.1.1 Bacteria 1TQ8A@1239,3F3PS@33958,4H9UF@91061,COG1293@1,COG1293@2 NA|NA|NA K Fibronectin-binding protein PGHMIELC_01079 220668.lp_1795 1.9e-66 258.5 Lactobacillaceae Bacteria 1VCKC@1239,3F7BA@33958,4HPTV@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator PGHMIELC_01080 220668.lp_1796 7e-161 573.2 Lactobacillaceae degV Bacteria 1TRM7@1239,3F40W@33958,4HBIR@91061,COG1307@1,COG1307@2 NA|NA|NA S EDD domain protein, DegV family PGHMIELC_01081 220668.lp_1797 8.3e-78 296.2 Bacteria yjcF 3.5.4.33,4.4.1.8 ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941,R10223 RC00056,RC00069,RC00382,RC00477,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007,ko03016 Bacteria COG2153@1,COG2153@2 NA|NA|NA K protein acetylation PGHMIELC_01082 220668.lp_1798 3.4e-132 477.6 Lactobacillaceae Bacteria 1VCPB@1239,3F69G@33958,4HN1D@91061,COG5523@1,COG5523@2 NA|NA|NA S Protein of unknown function (DUF975) PGHMIELC_01083 220668.lp_1799 4.3e-10 72.0 Lactobacillaceae Bacteria 1U5RH@1239,2C6I8@1,309UV@2,3F6DF@33958,4IFFN@91061 NA|NA|NA PGHMIELC_01084 220668.lp_1800 1.6e-48 198.4 Lactobacillaceae Bacteria 1U682@1239,2A1CK@1,30PJJ@2,3F7A1@33958,4IFYS@91061 NA|NA|NA PGHMIELC_01085 220668.lp_1801 1.4e-147 528.9 Lactobacillaceae 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSNU@1239,3F3JH@33958,4H9TY@91061,COG1085@1,COG1085@2 NA|NA|NA C Domain of unknown function (DUF4931) PGHMIELC_01086 220668.lp_1803 2.5e-209 734.6 Lactobacillaceae pmrB Bacteria 1UZKT@1239,3F4QJ@33958,4HDHS@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_01087 1158602.I590_03639 4.6e-12 77.4 Enterococcaceae Bacteria 1W304@1239,2905K@1,2ZMVG@2,4B351@81852,4I0TS@91061 NA|NA|NA PGHMIELC_01088 220668.lp_1806 6.2e-51 206.5 Lactobacillaceae XK27_08430 Bacteria 1VIJK@1239,2ED3T@1,3370N@2,3F765@33958,4HPGM@91061 NA|NA|NA S Staphylococcal protein of unknown function (DUF960) PGHMIELC_01089 220668.lp_1807 5.2e-129 467.2 Lactobacillaceae yejC Bacteria 1V46X@1239,3F4FJ@33958,4HI49@91061,COG4420@1,COG4420@2 NA|NA|NA S Protein of unknown function (DUF1003) PGHMIELC_01090 220668.lp_1809 2.5e-134 485.0 Lactobacillaceae XK27_00890 ko:K08974 ko00000 Bacteria 1UYD5@1239,3F4QH@33958,4HBE3@91061,COG2035@1,COG2035@2 NA|NA|NA S Domain of unknown function (DUF368) PGHMIELC_01091 220668.lp_1811 9.3e-245 852.4 Lactobacillaceae cycA GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease PGHMIELC_01092 220668.lp_1812 1.9e-113 415.6 Lactobacillaceae Bacteria 1V3YR@1239,2BVD0@1,32QT1@2,3F67T@33958,4HK85@91061 NA|NA|NA PGHMIELC_01093 220668.lp_1813 4.1e-59 233.8 Lactobacillaceae Bacteria 1U65D@1239,2A40M@1,30SJ5@2,3F73D@33958,4IFV6@91061 NA|NA|NA PGHMIELC_01094 220668.lp_1814 1.8e-279 968.0 Lactobacillaceae lldP ko:K03303 ko00000,ko02000 2.A.14 Bacteria 1TQNM@1239,3F4EG@33958,4HAF3@91061,COG1620@1,COG1620@2 NA|NA|NA C L-lactate permease PGHMIELC_01095 220668.lp_1815 5.1e-227 793.5 Lactobacillaceae Bacteria 1UFPM@1239,29UYR@1,30GBR@2,3F4MC@33958,4IEVQ@91061 NA|NA|NA PGHMIELC_01096 60520.HR47_02920 1.1e-127 462.6 Lactobacillaceae ispD GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 1.1.1.405,2.7.7.40,2.7.7.60,4.6.1.12 ko:K00991,ko:K12506,ko:K21030,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 M00096 R01525,R02921,R05633,R05637 RC00002,RC00089,RC01440 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3M7@1239,3F4WQ@33958,4HFH7@91061,COG1211@1,COG1211@2 NA|NA|NA I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate PGHMIELC_01097 60520.HR47_02925 1e-190 672.5 Lactobacillaceae tarJ 1.1.1.137,1.1.1.303,1.1.1.4,1.1.1.405 ko:K00004,ko:K05352,ko:K21680 ko00040,ko00650,ko01100,map00040,map00650,map01100 R01524,R01525,R02855,R02946,R10504 RC00089,RC00205,RC00525 ko00000,ko00001,ko01000 Bacteria 1TQSR@1239,3F4VQ@33958,4HCCH@91061,COG1063@1,COG1063@2 NA|NA|NA E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate PGHMIELC_01098 60520.HR47_02930 9.5e-195 686.0 Lactobacillaceae tarK 2.7.8.14,2.7.8.47 ko:K18704 R11614,R11621 ko00000,ko01000 Bacteria 1TSTN@1239,3F4WC@33958,4HBRD@91061,COG1887@1,COG1887@2 NA|NA|NA H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase PGHMIELC_01099 60520.HR47_02935 0.0 1219.5 Lactobacillaceae tarL 2.7.8.14,2.7.8.47 ko:K18704 R11614,R11621 ko00000,ko01000 Bacteria 1TSTN@1239,3FBDI@33958,4IPPR@91061,COG1887@1,COG1887@2 NA|NA|NA H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase PGHMIELC_01100 220668.lp_1820 3.6e-91 340.9 Lactobacillaceae paiA 2.3.1.57 ko:K22441 ko00000,ko01000 Bacteria 1V1RG@1239,3F73H@33958,4HFN7@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain PGHMIELC_01101 220668.lp_1821 1.8e-72 278.5 Lactobacillaceae mgrA Bacteria 1VBNV@1239,3F70R@33958,4HMCJ@91061,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein PGHMIELC_01102 220668.lp_1822 1.2e-239 835.5 Lactobacillaceae gshR1 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1TS0Z@1239,3F3K2@33958,4HBYB@91061,COG1249@1,COG1249@2 NA|NA|NA C Glutathione reductase PGHMIELC_01103 220668.lp_1823 2.1e-51 208.4 Lactobacillaceae Bacteria 1U6TS@1239,29PND@1,30AKK@2,3F8H3@33958,4IGMK@91061 NA|NA|NA PGHMIELC_01104 220668.lp_1824 6.3e-246 856.3 Lactobacillaceae Bacteria 1VX75@1239,3FC15@33958,4HX3T@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family group 2 PGHMIELC_01105 220668.lp_1825 7.5e-275 952.6 Lactobacillaceae ko:K13687 ko00000,ko01000,ko01003 GT89 Bacteria 1VCF5@1239,3F615@33958,4HQ4B@91061,COG1807@1,COG1807@2 NA|NA|NA M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family PGHMIELC_01106 220668.lp_1833 1.4e-156 558.9 Lactobacillaceae xerD ko:K04763 ko00000,ko03036 Bacteria 1UFH8@1239,3F3KV@33958,4IES1@91061,COG4974@1,COG4974@2 NA|NA|NA L Phage integrase, N-terminal SAM-like domain PGHMIELC_01107 220668.lp_1834 4.2e-32 143.3 Lactobacillaceae Bacteria 1U6HN@1239,29PF4@1,30ADA@2,3F7XW@33958,4IG9Y@91061 NA|NA|NA S YozE SAM-like fold PGHMIELC_01108 220668.lp_1835 1e-95 355.9 Lactobacillaceae msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 ko00000,ko01000 Bacteria 1TQ3E@1239,3F3YI@33958,4HAIV@91061,COG0225@1,COG0225@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine PGHMIELC_01109 220668.lp_1836 4e-80 303.9 Lactobacillaceae msrB 1.8.4.11,1.8.4.12 ko:K07305,ko:K12267 ko00000,ko01000 Bacteria 1UPN0@1239,3F6H4@33958,4HGWN@91061,COG0229@1,COG0229@2 NA|NA|NA O peptide methionine sulfoxide reductase PGHMIELC_01110 220668.lp_1837 6.4e-168 596.7 Lactobacillaceae ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1TPH6@1239,3F3PJ@33958,4H9T8@91061,COG1227@1,COG1227@2 NA|NA|NA C inorganic pyrophosphatase PGHMIELC_01111 220668.lp_1838 3.5e-177 627.5 Lactobacillaceae Bacteria 1UYS5@1239,3F48B@33958,4HF07@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator PGHMIELC_01112 220668.lp_1839 0.0 1595.9 Lactobacillaceae parC GO:0005575,GO:0005622,GO:0005623,GO:0009330,GO:0032991,GO:0044424,GO:0044464 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TRE7@1239,3F3MJ@33958,4HAQB@91061,COG0188@1,COG0188@2 NA|NA|NA L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule PGHMIELC_01113 220668.lp_1840 0.0 1298.1 Lactobacillaceae parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470,ko:K02622 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TQCF@1239,3F430@33958,4H9UC@91061,COG0187@1,COG0187@2 NA|NA|NA L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule PGHMIELC_01114 220668.lp_1842 5.2e-105 387.1 Lactobacillaceae plsY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15,3.5.1.104 ko:K08591,ko:K22278 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1VA3J@1239,3F543@33958,4HC55@91061,COG0344@1,COG0344@2 NA|NA|NA I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP PGHMIELC_01115 220668.lp_1843 2.2e-170 604.7 Lactobacillaceae lacX 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 1U26T@1239,3F3KT@33958,4HA4J@91061,COG2017@1,COG2017@2 NA|NA|NA G Aldose 1-epimerase PGHMIELC_01116 220668.lp_1845 2.3e-257 894.4 Lactobacillaceae hslU GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03667 ko00000,ko03110 Bacteria 1TPKQ@1239,3F3WB@33958,4HA83@91061,COG1220@1,COG1220@2 NA|NA|NA O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis PGHMIELC_01117 1136177.KCA1_1594 6.7e-93 346.7 Lactobacillaceae hslV GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 ko:K01419 ko00000,ko01000,ko01002 Bacteria 1TPXK@1239,3F4HS@33958,4H9PD@91061,COG5405@1,COG5405@2 NA|NA|NA O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery PGHMIELC_01118 220668.lp_1847 1.5e-177 628.6 Lactobacillaceae xerC ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 1TPQB@1239,3F44K@33958,4HARA@91061,COG4974@1,COG4974@2 NA|NA|NA D Belongs to the 'phage' integrase family. XerC subfamily PGHMIELC_01119 220668.lp_1848 2.5e-250 870.9 Lactobacillaceae trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 ko00000,ko01000,ko03016,ko03036 Bacteria 1TP67@1239,3F3WW@33958,4HB27@91061,COG1206@1,COG1206@2 NA|NA|NA J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs PGHMIELC_01120 220668.lp_1850 0.0 1361.3 Lactobacillaceae topA 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria 1TPUS@1239,3F3VS@33958,4HA6C@91061,COG0550@1,COG0550@2 NA|NA|NA L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone PGHMIELC_01121 220668.lp_1852 8e-157 559.7 Lactobacillaceae dprA GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 ko:K04096 ko00000 Bacteria 1TPP7@1239,3F41U@33958,4HGWM@91061,COG0758@1,COG0758@2 NA|NA|NA LU DNA protecting protein DprA PGHMIELC_01122 220668.lp_1853 9e-136 489.6 Lactobacillaceae rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1V1D6@1239,3F3JC@33958,4HB7M@91061,COG0164@1,COG0164@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids PGHMIELC_01123 220668.lp_1854 1.8e-161 575.1 Lactobacillaceae ylqF GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 ko:K14540 ko00000,ko03009 Bacteria 1TQGK@1239,3F3MI@33958,4HA4D@91061,COG1161@1,COG1161@2 NA|NA|NA S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity PGHMIELC_01125 220668.lp_1856 1.4e-228 798.5 Lactobacillaceae XK27_05470 Bacteria 1TPDQ@1239,3F58A@33958,4HADW@91061,COG0620@1,COG0620@2 NA|NA|NA E Methionine synthase PGHMIELC_01126 220668.lp_1857 8.9e-170 602.8 Lactobacillaceae cpsY Bacteria 1TP3E@1239,3F4VM@33958,4HC5J@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator, LysR family PGHMIELC_01127 220668.lp_1859 6.5e-125 453.4 Lactobacillaceae 1.5.1.40 ko:K06988 ko00000,ko01000 Bacteria 1V5YV@1239,3F4G0@33958,4HH6T@91061,COG2085@1,COG2085@2 NA|NA|NA S NADP oxidoreductase coenzyme F420-dependent PGHMIELC_01128 220668.lp_1860 7.4e-197 693.0 Lactobacillaceae XK27_00915 Bacteria 1TRBN@1239,3F4KZ@33958,4HBYT@91061,COG2141@1,COG2141@2 NA|NA|NA C Luciferase-like monooxygenase PGHMIELC_01129 220668.lp_1863 3.3e-251 874.0 Lactobacillaceae emrY Bacteria 1VSW8@1239,3F4AW@33958,4HUQC@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_01130 220668.lp_1864 1.2e-261 908.7 Lactobacillaceae ctpA GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 1TPBI@1239,3F3SS@33958,4HAKE@91061,COG0793@1,COG0793@2,COG3409@1,COG3409@2 NA|NA|NA M Belongs to the peptidase S41A family PGHMIELC_01131 220668.lp_1865 3.4e-35 153.7 Lactobacillaceae yozE Bacteria 1VFI4@1239,3F7ZP@33958,4HR7P@91061,COG4479@1,COG4479@2 NA|NA|NA S Belongs to the UPF0346 family PGHMIELC_01132 220668.lp_1866 3.1e-113 414.5 Lactobacillaceae ypmS Bacteria 1VF0K@1239,3F5K5@33958,4HIYN@91061,COG4698@1,COG4698@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2140) PGHMIELC_01133 220668.lp_1867 5.1e-149 533.9 Lactobacillaceae ypmR GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0016298,GO:0016787,GO:0016788,GO:0052689 Bacteria 1V1HR@1239,3F4N0@33958,4HDXS@91061,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase PGHMIELC_01134 220668.lp_1868 1.5e-147 528.9 Lactobacillaceae DegV Bacteria 1TRZ4@1239,3F4CW@33958,4HBR8@91061,COG1307@1,COG1307@2 NA|NA|NA S EDD domain protein, DegV family PGHMIELC_01135 220668.lp_1869 5.1e-92 343.6 Lactobacillaceae folA 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 Bacteria 1VB80@1239,3F6Y4@33958,4HIGJ@91061,COG0262@1,COG0262@2 NA|NA|NA H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis PGHMIELC_01136 220668.lp_1870 1.1e-188 665.6 Lactobacillaceae thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSIR@1239,3F3SB@33958,4H9QS@91061,COG0207@1,COG0207@2 NA|NA|NA F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis PGHMIELC_01137 220668.lp_1871 0.0 1211.1 Lactobacillaceae yfmR ko:K15738 ko00000,ko02000 3.A.1.120.6 Bacteria 1TPAX@1239,3FC7W@33958,4H9TK@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein PGHMIELC_01138 220668.lp_1872 9.6e-85 319.3 Lactobacillaceae Bacteria 1V54W@1239,2A42J@1,30SMC@2,3F3R1@33958,4HGI5@91061 NA|NA|NA PGHMIELC_01139 220668.lp_1873 1.1e-228 798.9 Lactobacillaceae cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 1TQ2A@1239,3F3VH@33958,4HB2W@91061,COG0617@1,COG0617@2 NA|NA|NA J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate PGHMIELC_01140 220668.lp_1874 5.4e-144 516.9 Lactobacillaceae dapB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 iJN678.dapB,iNJ661.Rv2773c,iYO844.BSU22490 Bacteria 1TR9D@1239,3F3MA@33958,4HA5X@91061,COG0289@1,COG0289@2 NA|NA|NA E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate PGHMIELC_01141 220668.lp_1876 9.7e-149 532.7 Lactobacillaceae 3.1.3.102,3.1.3.104 ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V2JE@1239,3F3Z7@33958,4HWAW@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase PGHMIELC_01142 220668.lp_1877 4.7e-206 723.8 Lactobacillaceae Bacteria 1TT97@1239,3F3ND@33958,4HAIA@91061,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat protein PGHMIELC_01143 1400520.LFAB_08160 1.1e-40 172.2 Lactobacillaceae hup ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 1V9XQ@1239,3F6YN@33958,4HKF2@91061,COG0776@1,COG0776@2 NA|NA|NA L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions PGHMIELC_01144 220668.lp_1881 2.7e-249 867.5 Lactobacillaceae der GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.399,1.1.1.95 ko:K00058,ko:K03977 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 Bacteria 1TPNM@1239,3F4V0@33958,4HAJ6@91061,COG1160@1,COG1160@2 NA|NA|NA S GTPase that plays an essential role in the late steps of ribosome biogenesis PGHMIELC_01145 220668.lp_1882 1.8e-213 748.4 Lactobacillaceae rpsA 1.17.7.4 ko:K02945,ko:K03527 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 Bacteria 1TQ9N@1239,3F4DQ@33958,4H9PX@91061,COG0539@1,COG0539@2 NA|NA|NA J Ribosomal protein S1 PGHMIELC_01146 220668.lp_1883 3.8e-117 427.6 Lactobacillaceae cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.17.7.4,2.5.1.19,2.7.1.26,2.7.4.25,2.7.7.2,6.3.2.1 ko:K00800,ko:K00945,ko:K02945,ko:K03527,ko:K03977,ko:K11753,ko:K13799 ko00240,ko00400,ko00410,ko00740,ko00770,ko00900,ko01100,ko01110,ko01130,ko01230,ko03010,map00240,map00400,map00410,map00740,map00770,map00900,map01100,map01110,map01130,map01230,map03010 M00022,M00052,M00096,M00119,M00125,M00178 R00158,R00161,R00512,R00549,R01665,R02473,R03460,R05884,R08210 RC00002,RC00017,RC00096,RC00141,RC00350,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03009,ko03011 iPC815.YPO1391,iSDY_1059.SDY_2348 Bacteria 1V3IA@1239,3F3W4@33958,4HFZE@91061,COG0283@1,COG0283@2 NA|NA|NA F Belongs to the cytidylate kinase family. Type 1 subfamily PGHMIELC_01147 220668.lp_1884 2e-19 102.8 Lactobacillaceae Bacteria 1VFEU@1239,3F6WV@33958,4HNW5@91061,COG1388@1,COG1388@2 NA|NA|NA M Lysin motif PGHMIELC_01148 220668.lp_1885 6.2e-271 939.5 Lactobacillaceae recQ1 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPN5@1239,3F4PY@33958,4H9QP@91061,COG0514@1,COG0514@2 NA|NA|NA L ATP-dependent DNA helicase RecQ PGHMIELC_01149 220668.lp_1886 3.6e-196 690.6 Lactobacillaceae ypbB 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQU9@1239,3F45N@33958,4HJ71@91061,COG4955@1,COG4955@2 NA|NA|NA S Helix-turn-helix domain PGHMIELC_01150 220668.lp_1887 1.2e-95 355.9 Lactobacillaceae Bacteria 1V4BW@1239,3F4HD@33958,4HHFT@91061,COG3601@1,COG3601@2 NA|NA|NA U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins PGHMIELC_01151 220668.lp_1888 1.1e-130 472.6 Lactobacillaceae rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.21,5.4.99.22 ko:K06178,ko:K06182,ko:K06183 ko00000,ko01000,ko03009 Bacteria 1TP68@1239,3F402@33958,4H9MU@91061,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family PGHMIELC_01152 220668.lp_1889 7.9e-103 379.8 Lactobacillaceae scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K06024 ko00000,ko03036 Bacteria 1V6HI@1239,3F5RN@33958,4HIQ0@91061,COG1386@1,COG1386@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves PGHMIELC_01153 220668.lp_1890 8.2e-129 466.5 Lactobacillaceae scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K05896 ko00000,ko03036 Bacteria 1TRW3@1239,3FCCZ@33958,4HA6Q@91061,COG1354@1,COG1354@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves PGHMIELC_01154 220668.lp_1891 4.8e-69 266.9 Lactobacillaceae ribT ko:K02859 ko00000 Bacteria 1VAD7@1239,3F7QC@33958,4HKR2@91061,COG0454@1,COG0456@2 NA|NA|NA K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases PGHMIELC_01155 220668.lp_1892 1.1e-164 585.9 Lactobacillaceae xerD ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 1TQRG@1239,3F3V9@33958,4HAEX@91061,COG4974@1,COG4974@2 NA|NA|NA D recombinase XerD PGHMIELC_01156 220668.lp_1893 2.9e-170 604.4 Lactobacillaceae cvfB ko:K00243 ko00000 Bacteria 1TQ1Z@1239,3F44W@33958,4HDAZ@91061,COG2996@1,COG2996@2 NA|NA|NA S S1 domain PGHMIELC_01157 220668.lp_1894 1.5e-74 285.4 Lactobacillaceae yeaL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1V7JN@1239,3F68U@33958,4HINS@91061,COG2707@1,COG2707@2 NA|NA|NA S Protein of unknown function (DUF441) PGHMIELC_01158 220668.lp_1897 0.0 1124.0 Lactobacillaceae pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009986,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0022607,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40,2.7.7.4 ko:K00873,ko:K00958 ko00010,ko00230,ko00261,ko00450,ko00620,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00261,map00450,map00620,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050,M00176,M00596 R00200,R00430,R00529,R01138,R01858,R02320,R04929 RC00002,RC00015,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iECO103_1326.ECO103_1819,iPC815.YPO2393 Bacteria 1TPGG@1239,3F3JU@33958,4H9VY@91061,COG0469@1,COG0469@2 NA|NA|NA G Belongs to the pyruvate kinase family PGHMIELC_01159 220668.lp_1898 1.5e-180 638.6 Lactobacillaceae pfkA GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 iYO844.BSU29190 Bacteria 1TPF4@1239,3F4CC@33958,4HAPN@91061,COG0205@1,COG0205@2 NA|NA|NA F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis PGHMIELC_01160 220668.lp_1899 0.0 2157.9 Lactobacillaceae dnaE 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPYG@1239,3F4AM@33958,4H9T3@91061,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase PGHMIELC_01161 60520.HR47_08375 7.3e-29 132.5 Lactobacillaceae Bacteria 1W2U5@1239,2DGWH@1,2ZXI7@2,3F8TZ@33958,4I0PU@91061 NA|NA|NA S Protein of unknown function (DUF2929) PGHMIELC_01162 220668.lp_1903 0.0 1524.2 Lactobacillaceae clpB GO:0003674,GO:0005488,GO:0005515,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0042802,GO:0043170,GO:0044238,GO:0071704,GO:1901564 ko:K03694,ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Bacteria 1TPMU@1239,3F3RV@33958,4HACY@91061,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE PGHMIELC_01163 220668.lp_1904 1.4e-234 818.5 Lactobacillaceae pepT GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0034701,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045148,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.4 ko:K01258 ko00000,ko01000,ko01002 Bacteria 1TP3A@1239,3F45V@33958,4HAZE@91061,COG2195@1,COG2195@2 NA|NA|NA E Cleaves the N-terminal amino acid of tripeptides PGHMIELC_01164 220668.lp_1905 1.1e-197 695.7 Lactobacillaceae yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.16 ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ27@1239,3F3ZD@33958,4H9NY@91061,COG0327@1,COG0327@2 NA|NA|NA S Belongs to the GTP cyclohydrolase I type 2 NIF3 family PGHMIELC_01165 220668.lp_1906 1.6e-126 458.8 Lactobacillaceae trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 ko00000,ko01000,ko03016 Bacteria 1V3I4@1239,3F4GT@33958,4HHIM@91061,COG2384@1,COG2384@2 NA|NA|NA S SAM-dependent methyltransferase PGHMIELC_01166 220668.lp_1908 6.9e-223 779.6 Lactobacillaceae Bacteria 1V8CF@1239,3F59M@33958,4IF0T@91061,COG3307@1,COG3307@2 NA|NA|NA M O-Antigen ligase PGHMIELC_01167 220668.lp_1909 5.4e-120 437.2 Lactobacillaceae drrB ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TS7U@1239,3F57J@33958,4HCH1@91061,COG0842@1,COG0842@2 NA|NA|NA U ABC-2 type transporter PGHMIELC_01168 220668.lp_1910 3.2e-167 594.3 Lactobacillaceae drrA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPJE@1239,3F58G@33958,4HB5U@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter PGHMIELC_01169 220668.lp_1911 3.1e-84 317.8 Lactobacillaceae ko:K22296 ko00000,ko03000 Bacteria 1V40V@1239,3F5C5@33958,4HI52@91061,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein PGHMIELC_01170 220668.lp_1912 0.0 1586.6 Lactobacillaceae ppsA GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 iEcE24377_1341.EcE24377A_1919,iYL1228.KPN_02160 Bacteria 1TPK8@1239,3F3U1@33958,4ISER@91061,COG0574@1,COG0574@2,COG1080@1,COG1080@2 NA|NA|NA H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate PGHMIELC_01171 220668.lp_1913 7.8e-61 239.6 Lactobacillaceae Bacteria 1VJIW@1239,3F707@33958,4HW5V@91061,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain PGHMIELC_01172 220668.lp_1914 2.1e-91 341.7 Lactobacillaceae yetL GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 ko:K15973 ko00000,ko03000 Bacteria 1VIXS@1239,3FC7J@33958,4HPYM@91061,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein PGHMIELC_01173 220668.lp_1915 1.7e-207 728.4 Lactobacillaceae Bacteria 1U5H7@1239,2C353@1,309Q7@2,3F5XZ@33958,4IF82@91061 NA|NA|NA PGHMIELC_01174 220668.lp_1916 1.2e-216 758.8 Lactobacillaceae Bacteria 1V7GP@1239,3F42R@33958,4HJ4R@91061,COG1835@1,COG1835@2 NA|NA|NA I transferase activity, transferring acyl groups other than amino-acyl groups PGHMIELC_01175 220668.lp_1918 1.1e-181 642.5 Lactobacillaceae Bacteria 1TPGA@1239,3F4HK@33958,4HER3@91061,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase PGHMIELC_01176 220668.lp_1919 0.0 1399.0 Lactobacillaceae 3.6.3.6 ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 3.A.3.3 Bacteria 1TPF5@1239,3F55J@33958,4HVA4@91061,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus PGHMIELC_01177 220668.lp_1920 6.8e-245 852.8 Lactobacillaceae eno GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0043236,GO:0050840 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 1V12I@1239,3FCCA@33958,4HTD2@91061,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis PGHMIELC_01178 220668.lp_1921 6.5e-241 839.7 Lactobacillaceae ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1TPRN@1239,3FCCM@33958,4H9VV@91061,COG0477@1,COG2223@1,COG2223@2,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_01179 220668.lp_1922 4.3e-77 293.9 Lactobacillaceae Bacteria 1VMZX@1239,3F82U@33958,4HMTC@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator PGHMIELC_01180 220668.lp_1923 1.4e-209 735.3 Lactobacillaceae dapE 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMJ@1239,3F3N9@33958,4HB39@91061,COG0624@1,COG0624@2 NA|NA|NA E succinyl-diaminopimelate desuccinylase PGHMIELC_01181 220668.lp_1925 2.8e-310 1070.5 Lactobacillaceae naoX Bacteria 1TPWW@1239,3FBSF@33958,4HA11@91061,COG0446@1,COG0446@2,COG0607@1,COG0607@2 NA|NA|NA P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain PGHMIELC_01182 220668.lp_1926 8e-137 493.0 Lactobacillaceae ko:K02444,ko:K16785,ko:K22103 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1V1VH@1239,3F3UT@33958,4HG12@91061,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain PGHMIELC_01183 220668.lp_1927 1.7e-108 398.7 Lactobacillaceae yjhB 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 1U7WX@1239,3F4BS@33958,4HHQT@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain PGHMIELC_01184 220668.lp_1928 9.1e-71 272.7 Lactobacillaceae yneH 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1V3QC@1239,3F660@33958,4HH0I@91061,COG1393@1,COG1393@2 NA|NA|NA P ArsC family PGHMIELC_01185 220668.lp_1929 1.4e-68 265.4 Lactobacillaceae ko:K13281 ko00000,ko01000 Bacteria 1VGGK@1239,3F7CK@33958,4HP7S@91061,COG3272@1,COG3272@2 NA|NA|NA S Protein of unknown function (DUF1722) PGHMIELC_01186 220668.lp_1930 2.3e-113 414.8 Bacteria Bacteria COG0702@1,COG0702@2 NA|NA|NA GM epimerase PGHMIELC_01187 220668.lp_1931 0.0 1113.2 Firmicutes CP_1020 Bacteria 1TS1R@1239,COG4715@1,COG4715@2 NA|NA|NA S Zinc finger, swim domain protein PGHMIELC_01188 220668.lp_1932 1.4e-119 435.6 Bacilli ppaX_1 3.1.3.18,3.6.1.1 ko:K01091,ko:K06019 ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1UYBR@1239,4IPXP@91061,COG0546@1,COG0546@2 NA|NA|NA S haloacid dehalogenase-like hydrolase PGHMIELC_01189 220668.lp_1933 1.5e-80 305.8 Lactobacillaceae maa 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 ko00000,ko01000 Bacteria 1TQEX@1239,3F47V@33958,4HAJ0@91061,COG0110@1,COG0110@2 NA|NA|NA S Maltose O-acetyltransferase PGHMIELC_01190 220668.lp_1934 1.3e-128 465.7 Lactobacillaceae Bacteria 1TS9A@1239,3F6D3@33958,4HCBF@91061,COG1737@1,COG1737@2 NA|NA|NA K Helix-turn-helix domain, rpiR family PGHMIELC_01191 220668.lp_1935 3.4e-160 570.9 Lactobacillaceae Bacteria 1VSYU@1239,3F4J2@33958,4HU15@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha beta hydrolase PGHMIELC_01192 220668.lp_1936 9e-113 412.9 Lactobacillaceae Bacteria 1VS7E@1239,3F5Q2@33958,4HT7A@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family PGHMIELC_01193 220668.lp_1937 2.7e-76 291.2 Lactobacillaceae Bacteria 1VBEN@1239,3F75W@33958,4HM8H@91061,COG4334@1,COG4334@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2255) PGHMIELC_01194 220668.lp_1938 8e-160 569.7 Lactobacillaceae Bacteria 1TP77@1239,3F3VP@33958,4HAZB@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator PGHMIELC_01195 220668.lp_1939 1.8e-170 605.1 Lactobacillaceae Bacteria 1TQ0M@1239,3F4EJ@33958,4HA8M@91061,COG0604@1,COG0604@2 NA|NA|NA C nadph quinone reductase PGHMIELC_01196 1400520.LFAB_04350 4.7e-17 93.6 Lactobacillaceae Bacteria 1VSYU@1239,3F4J2@33958,4HU15@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha beta hydrolase PGHMIELC_01197 220668.lp_1941 1e-262 912.1 Lactobacillaceae nox Bacteria 1TPWW@1239,3F5ZI@33958,4IF8P@91061,COG0446@1,COG0446@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain PGHMIELC_01198 220668.lp_1942 3.6e-103 380.9 Lactobacillaceae desR ko:K02479,ko:K07693 ko02020,map02020 M00479 ko00000,ko00001,ko00002,ko02022 Bacteria 1TVTF@1239,3F4VH@33958,4HAJW@91061,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon PGHMIELC_01199 220668.lp_1943 4.2e-203 713.8 Lactobacillaceae desK GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K07778 ko02020,map02020 M00479 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TSUE@1239,3F3VR@33958,4HB9N@91061,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase PGHMIELC_01200 220668.lp_1944 1.3e-134 485.7 Lactobacillaceae yvfS ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V7QG@1239,3F5Q7@33958,4HFU4@91061,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 type transporter PGHMIELC_01201 220668.lp_1945 2.6e-158 564.7 Lactobacillaceae yvfR ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TRM5@1239,3FC3M@33958,4HFBN@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter PGHMIELC_01203 220668.lp_1947 6e-82 310.1 Lactobacillaceae ko:K03827 ko00000,ko01000 Bacteria 1UI5X@1239,3FBSE@33958,4HWD1@91061,COG0454@1,COG0454@2 NA|NA|NA K Acetyltransferase (GNAT) domain PGHMIELC_01204 220668.lp_1948 2.1e-73 281.6 Lactobacillaceae Bacteria 1U6DA@1239,3F7NB@33958,4IG51@91061,COG1846@1,COG1846@2 NA|NA|NA K MarR family PGHMIELC_01205 220668.lp_1949 3.8e-114 417.5 Lactobacillaceae Bacteria 1UXHA@1239,3F6Z6@33958,4HG9V@91061,COG2364@1,COG2364@2 NA|NA|NA S Psort location CytoplasmicMembrane, score PGHMIELC_01206 220668.lp_1954 3.9e-162 577.4 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TP4J@1239,3F3YW@33958,4HBGH@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter, ATP-binding protein PGHMIELC_01207 220668.lp_1955 2.3e-128 464.9 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1GX@1239,3F52P@33958,4HG2P@91061,COG1277@1,COG1277@2 NA|NA|NA S ABC-2 family transporter protein PGHMIELC_01208 220668.lp_1956 3.6e-199 700.7 Lactobacillaceae Bacteria 1U6DM@1239,29PBN@1,30A9W@2,3F7NR@33958,4IG5C@91061 NA|NA|NA PGHMIELC_01209 220668.lp_1957 9.2e-203 712.6 Lactobacillaceae Bacteria 1U692@1239,29P86@1,30A68@2,3F7C4@33958,4IG07@91061 NA|NA|NA PGHMIELC_01210 220668.lp_1958 4.8e-165 587.0 Lactobacillaceae ytrB ko:K01990,ko:K16921 ko02010,map02010 M00254,M00584 ko00000,ko00001,ko00002,ko02000 3.A.1 Bacteria 1TS5Y@1239,3F4BF@33958,4HBUA@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter, ATP-binding protein PGHMIELC_01211 220668.lp_1959 9.5e-65 252.7 Lactobacillaceae ko:K07978,ko:K07979 ko00000,ko03000 Bacteria 1VFD0@1239,3F7AX@33958,4HNIT@91061,COG1725@1,COG1725@2 NA|NA|NA K helix_turn_helix gluconate operon transcriptional repressor PGHMIELC_01212 220668.lp_1962 4.6e-197 693.7 Lactobacillaceae sigA GO:0000988,GO:0000990,GO:0001098,GO:0001101,GO:0001108,GO:0001666,GO:0002791,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032879,GO:0032880,GO:0036293,GO:0040007,GO:0042221,GO:0043175,GO:0043254,GO:0044087,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051173,GO:0051223,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070063,GO:0070201,GO:0070482,GO:0071944,GO:0080090,GO:0090087,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:1903530,GO:2000112,GO:2000142,GO:2001141 ko:K03086,ko:K03087 ko02026,ko05111,map02026,map05111 ko00000,ko00001,ko03021 Bacteria 1TPD6@1239,3F4CF@33958,4HB1H@91061,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth PGHMIELC_01213 220668.lp_1963 0.0 1226.8 Lactobacillaceae dnaG ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1TQ0X@1239,3F3N1@33958,4HAG2@91061,COG0358@1,COG0358@2 NA|NA|NA L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication PGHMIELC_01214 220668.lp_1964 0.0 1354.0 Lactobacillaceae glyS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01879,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iJN678.glyS,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,ic_1306.c4378 Bacteria 1TNZ7@1239,3F4G8@33958,4H9NT@91061,COG0751@1,COG0751@2 NA|NA|NA J Glycyl-tRNA synthetase beta subunit PGHMIELC_01215 220668.lp_1965 6.8e-175 619.8 Lactobacillaceae glyQ GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016875,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 ko:K01878,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF1260.b3560,iAF987.Gmet_2942,iJO1366.b3560,iPC815.YPO4072,iY75_1357.Y75_RS19360 Bacteria 1TPW8@1239,3F3T8@33958,4HBCF@91061,COG0752@1,COG0752@2 NA|NA|NA J glycyl-tRNA synthetase alpha subunit PGHMIELC_01216 220668.lp_1966 3.4e-146 524.2 Lactobacillaceae recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1UZ19@1239,3F56P@33958,4HAHI@91061,COG1381@1,COG1381@2 NA|NA|NA L Involved in DNA repair and RecF pathway recombination PGHMIELC_01217 220668.lp_1967 5.6e-169 600.1 Lactobacillaceae era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 ko:K03595,ko:K06883 ko00000,ko03009,ko03029 Bacteria 1TP3R@1239,3F3WQ@33958,4H9WF@91061,COG1159@1,COG1159@2 NA|NA|NA S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism PGHMIELC_01218 220668.lp_1968 4.5e-73 280.4 Lactobacillaceae dgkA 2.7.1.107,2.7.1.66 ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 R02240,R05626 RC00002,RC00017 ko00000,ko00001,ko01000 iAF987.Gmet_2369,iSB619.SA_RS07900 Bacteria 1VEGR@1239,3F7DC@33958,4HNKN@91061,COG0818@1,COG0818@2 NA|NA|NA M Diacylglycerol kinase PGHMIELC_01219 220668.lp_1969 6.6e-84 316.6 Lactobacillaceae ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 1V6BU@1239,3F516@33958,4HIIE@91061,COG0319@1,COG0319@2 NA|NA|NA S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA PGHMIELC_01220 220668.lp_1970 3.4e-180 637.5 Lactobacillaceae phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06217 ko00000 Bacteria 1TP35@1239,3F4E7@33958,4HBD5@91061,COG1702@1,COG1702@2 NA|NA|NA T phosphate starvation-inducible protein PhoH PGHMIELC_01221 220668.lp_1972 2.6e-71 274.6 Lactobacillaceae yqeY ko:K09117 ko00000 Bacteria 1V6F2@1239,3F6I0@33958,4HIQP@91061,COG1610@1,COG1610@2 NA|NA|NA S YqeY-like protein PGHMIELC_01222 1136177.KCA1_1688 9.7e-23 112.1 Lactobacillaceae rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02970 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEHU@1239,3F81Y@33958,4HNPV@91061,COG0828@1,COG0828@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS21 family PGHMIELC_01223 220668.lp_1974 2.1e-151 541.6 Lactobacillaceae yqfL 2.7.11.33,2.7.4.28 ko:K09773 ko00000,ko01000 Bacteria 1TPG0@1239,3F3WK@33958,4HB0Q@91061,COG1806@1,COG1806@2 NA|NA|NA F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation PGHMIELC_01224 220668.lp_1975 1.7e-128 465.3 Lactobacillaceae Bacteria 1UZ4M@1239,3FBRG@33958,4HC3Z@91061,COG1028@1,COG1028@2 NA|NA|NA C Enoyl-(Acyl carrier protein) reductase PGHMIELC_01225 220668.lp_1976 4.5e-171 607.1 Lactobacillaceae nfo GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP1D@1239,3F42I@33958,4HB4F@91061,COG0648@1,COG0648@2 NA|NA|NA L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin PGHMIELC_01226 220668.lp_1977 2e-224 784.6 Lactobacillaceae tagB 2.7.8.14,2.7.8.44,2.7.8.47 ko:K18704,ko:K21285 R11558,R11614,R11621 RC00078 ko00000,ko01000 iYO844.BSU35760 Bacteria 1TSTN@1239,3F456@33958,4HBID@91061,COG1887@1,COG1887@2 NA|NA|NA M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase PGHMIELC_01227 220668.lp_1978 1.7e-159 568.5 Lactobacillaceae yitT Bacteria 1TRBT@1239,3F3PH@33958,4HBPR@91061,COG1284@1,COG1284@2 NA|NA|NA S Uncharacterised 5xTM membrane BCR, YitT family COG1284 PGHMIELC_01228 220668.lp_1979 3.2e-100 370.9 Lactobacillaceae msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 ko00000,ko01000 Bacteria 1TQ3E@1239,3F3YI@33958,4HAIV@91061,COG0225@1,COG0225@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine PGHMIELC_01229 220668.lp_1980 0.0 1208.0 Lactobacillaceae aspS 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPCN@1239,3F4PE@33958,4HACD@91061,COG0173@1,COG0173@2 NA|NA|NA J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) PGHMIELC_01230 220668.lp_1981 2.2e-243 847.8 Lactobacillaceae hisS 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP3D@1239,3F3M3@33958,4HAM2@91061,COG0124@1,COG0124@2 NA|NA|NA J histidyl-tRNA synthetase PGHMIELC_01231 220668.lp_1982 1.9e-155 555.1 Lactobacillaceae lytH GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria 1UYPW@1239,3F4F4@33958,4HBVT@91061,COG0860@1,COG0860@2,COG3103@1,COG4991@2 NA|NA|NA M N-acetylmuramoyl-L-alanine amidase PGHMIELC_01232 220668.lp_1983 1.2e-165 589.0 Lactobacillaceae yniA GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 Bacteria 1V1VZ@1239,3FCE0@33958,4HGP7@91061,COG3001@1,COG3001@2 NA|NA|NA G Fructosamine kinase PGHMIELC_01233 220668.lp_1985 2.2e-116 424.9 Lactobacillaceae 3.1.3.18 ko:K01091,ko:K07025 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1V3DR@1239,3F741@33958,4HGMU@91061,COG0546@1,COG0546@2 NA|NA|NA J HAD-hyrolase-like PGHMIELC_01234 220668.lp_1986 8.5e-78 296.2 Lactobacillaceae dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K07560 ko00000,ko01000,ko03016 Bacteria 1V6GH@1239,3F6GK@33958,4HINN@91061,COG1490@1,COG1490@2 NA|NA|NA J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality PGHMIELC_01235 220668.lp_1987 0.0 1427.5 Lactobacillaceae relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 iHN637.CLJU_RS16615,iYO844.BSU27600 Bacteria 1TNYZ@1239,3F44F@33958,4HBX7@91061,COG0317@1,COG0317@2 NA|NA|NA KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance PGHMIELC_01236 220668.lp_1988 9.6e-58 229.2 Lactobacillaceae Bacteria 1U65T@1239,2DKNW@1,30A40@2,3F74W@33958,4IFVP@91061 NA|NA|NA PGHMIELC_01237 220668.lp_1989 2.9e-134 484.6 Lactobacillaceae rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 ko00000,ko01000,ko03009 Bacteria 1V1CT@1239,3F64Z@33958,4HH8P@91061,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit PGHMIELC_01238 220668.lp_1990 4.5e-177 627.1 Lactobacillaceae prmA ko:K02687 ko00000,ko01000,ko03009 Bacteria 1TPKI@1239,3F47Z@33958,4HAMF@91061,COG2264@1,COG2264@2 NA|NA|NA J Ribosomal protein L11 methyltransferase PGHMIELC_01239 220668.lp_1991 3.6e-114 417.5 Lactobacillaceae mpg GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1E6@1239,3F59D@33958,4HG5E@91061,COG2094@1,COG2094@2 NA|NA|NA L Belongs to the DNA glycosylase MPG family PGHMIELC_01240 220668.lp_1992 1.4e-49 201.8 Lactobacillaceae Bacteria 1W026@1239,2FCQV@1,344U2@2,3F7FM@33958,4HZ7F@91061 NA|NA|NA PGHMIELC_01241 220668.lp_1994 1.4e-49 201.8 Lactobacillaceae Bacteria 1U633@1239,29P3S@1,30A1Z@2,3F6XC@33958,4IFSC@91061 NA|NA|NA PGHMIELC_01242 220668.lp_2015 0.0 1192.9 Lactobacillaceae lepA ko:K03596 ko05134,map05134 ko00000,ko00001 Bacteria 1TP0G@1239,3F3Z1@33958,4HASA@91061,COG0481@1,COG0481@2 NA|NA|NA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner PGHMIELC_01243 220668.lp_2016 6.1e-246 856.3 Lactobacillaceae dltD ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1TSZU@1239,3F3WE@33958,4HC3H@91061,COG3966@1,COG3966@2 NA|NA|NA M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) PGHMIELC_01244 220668.lp_2017 2.4e-34 151.0 Lactobacillaceae dltC GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K02078,ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1VFQI@1239,3F7Q1@33958,4HNIH@91061,COG0236@1,COG0236@2 NA|NA|NA J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall PGHMIELC_01245 220668.lp_2018 8.7e-234 815.8 Lactobacillaceae dltB ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1TP52@1239,3F4KK@33958,4HBQG@91061,COG1696@1,COG1696@2 NA|NA|NA M MBOAT, membrane-bound O-acyltransferase family PGHMIELC_01246 220668.lp_2019 2e-296 1024.2 Lactobacillaceae dltA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1TPTH@1239,3F49R@33958,4HAHU@91061,COG1020@1,COG1020@2 NA|NA|NA H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall PGHMIELC_01247 220668.lp_2020 8.8e-19 98.6 Lactobacillaceae dltX Bacteria 1U6XZ@1239,2DKST@1,30APB@2,3F8PK@33958,4IGS5@91061 NA|NA|NA S D-Ala-teichoic acid biosynthesis protein PGHMIELC_01248 220668.lp_2021 2.8e-197 694.5 Lactobacillaceae pbpX2 ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1V0GX@1239,3F4TH@33958,4HCXH@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase PGHMIELC_01249 220668.lp_2026 1.2e-184 652.5 Lactobacillaceae dnaJ ko:K03686 ko00000,ko03029,ko03110 Bacteria 1TP00@1239,3F490@33958,4H9KA@91061,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins PGHMIELC_01250 220668.lp_2027 0.0 1139.8 Lactobacillaceae dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 1TP1J@1239,3F48C@33958,4HA9S@91061,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein PGHMIELC_01251 220668.lp_2028 5.6e-80 303.9 Lactobacillaceae grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 ko:K03687 ko00000,ko03029,ko03110 Bacteria 1V6G2@1239,3F4DY@33958,4HIRK@91061,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ PGHMIELC_01252 220668.lp_2029 2.4e-195 688.0 Lactobacillaceae hrcA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K03705 ko00000,ko03000 Bacteria 1TQP7@1239,3F3ST@33958,4HAX5@91061,COG1420@1,COG1420@2 NA|NA|NA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons PGHMIELC_01253 220668.lp_2030 7.3e-132 476.5 Lactobacillaceae budA GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0047605 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 R02948 RC00812 ko00000,ko00001,ko01000 Bacteria 1V4AH@1239,3FCCX@33958,4HJ98@91061,COG3527@1,COG3527@2 NA|NA|NA Q Alpha-acetolactate decarboxylase PGHMIELC_01254 220668.lp_2031 1.2e-188 665.6 Lactobacillaceae ribF 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS06310 Bacteria 1TPKS@1239,3F3TG@33958,4H9KE@91061,COG0196@1,COG0196@2 NA|NA|NA H Belongs to the ribF family PGHMIELC_01255 220668.lp_2032 9.4e-172 609.4 Lactobacillaceae truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 ko00000,ko01000,ko03000,ko03016 iSB619.SA_RS06305 Bacteria 1TP9Y@1239,3F3NX@33958,4HA9X@91061,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs PGHMIELC_01256 220668.lp_2033 2.4e-87 328.2 Lactobacillaceae aroK GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615 1.1.1.25,2.7.1.71,4.2.1.10,4.2.3.4 ko:K00014,ko:K00891,ko:K03785,ko:K03786,ko:K13829,ko:K15546 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R02413,R03083,R03084 RC00002,RC00078,RC00206,RC00847,RC00848 ko00000,ko00001,ko00002,ko01000,ko03000 iAPECO1_1312.APECO1_1620,iECOK1_1307.ECOK1_0367,iECS88_1305.ECS88_0383,iUMN146_1321.UM146_15425,iUTI89_1310.UTI89_C0407,iYL1228.KPN_00332 Bacteria 1VA6Z@1239,3F7FE@33958,4HKD6@91061,COG0703@1,COG0703@2 NA|NA|NA F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate PGHMIELC_01257 220668.lp_2034 1.3e-196 692.2 Lactobacillaceae tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 ko:K00210,ko:K00220,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025,M00040 R00732,R01728 RC00125 ko00000,ko00001,ko00002,ko01000 iYO844.BSU22610 Bacteria 1TPXG@1239,3F589@33958,4HBI4@91061,COG0287@1,COG0287@2 NA|NA|NA E prephenate dehydrogenase PGHMIELC_01258 220668.lp_2035 2e-236 824.7 Lactobacillaceae aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 1.3.1.12,1.3.1.43,2.5.1.19 ko:K00210,ko:K00220,ko:K00800 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00022,M00025,M00040 R00732,R01728,R03460 RC00125,RC00350 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0345 Bacteria 1TPIH@1239,3F5B2@33958,4HBHZ@91061,COG0128@1,COG0128@2 NA|NA|NA E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate PGHMIELC_01259 220668.lp_2036 8.5e-93 346.3 Lactobacillaceae Bacteria 1VC0E@1239,2E0PE@1,32W87@2,3F60R@33958,4HKI6@91061 NA|NA|NA PGHMIELC_01260 220668.lp_2037 4.6e-216 756.9 Lactobacillaceae aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0976,iNJ661.Rv2540c Bacteria 1TQ40@1239,3F502@33958,4HA0H@91061,COG0082@1,COG0082@2 NA|NA|NA E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system PGHMIELC_01261 220668.lp_2038 1.3e-263 915.2 Lactobacillaceae ydiN GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015291,GO:0015292,GO:0016020,GO:0022804,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 5.4.99.5 ko:K04092,ko:K04516 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 Bacteria 1V18N@1239,3FBEJ@33958,4IPXQ@91061,COG1605@1,COG1605@2,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator PGHMIELC_01262 1136177.KCA1_1729 4.6e-50 203.8 Lactobacillaceae rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 ko:K02834 ko00000,ko03009 Bacteria 1VA0P@1239,3F6WZ@33958,4HII1@91061,COG0858@1,COG0858@2 NA|NA|NA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA PGHMIELC_01263 220668.lp_2040 0.0 1195.3 Lactobacillaceae infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K02519 ko00000,ko03012,ko03029 Bacteria 1TPAI@1239,3F3JV@33958,4HA8S@91061,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex PGHMIELC_01264 220668.lp_2041 1.6e-46 191.8 Lactobacillaceae ylxQ ko:K07590,ko:K07742 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEYG@1239,3F7ZK@33958,4HNY7@91061,COG1358@1,COG1358@2 NA|NA|NA J ribosomal protein PGHMIELC_01265 220668.lp_2042 9.5e-49 199.1 Lactobacillaceae ylxR ko:K02600,ko:K07742 ko00000,ko03009,ko03021 Bacteria 1VEJS@1239,3F7E2@33958,4HKBY@91061,COG2740@1,COG2740@2 NA|NA|NA K Protein of unknown function (DUF448) PGHMIELC_01266 220668.lp_2043 3.3e-217 760.8 Lactobacillaceae nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02600,ko:K02945 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03009,ko03011,ko03021 Bacteria 1TPB3@1239,3F3KZ@33958,4HA7F@91061,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination PGHMIELC_01267 220668.lp_2044 4.2e-83 313.9 Lactobacillaceae rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 ko:K09748 ko00000,ko03009 Bacteria 1V6KT@1239,3F6GZ@33958,4HH88@91061,COG0779@1,COG0779@2 NA|NA|NA J Required for maturation of 30S ribosomal subunits PGHMIELC_01268 220668.lp_2045 0.0 2881.7 Lactobacillaceae polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K02342,ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPAG@1239,3F4AN@33958,4H9RF@91061,COG2176@1,COG2176@2 NA|NA|NA L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity PGHMIELC_01269 220668.lp_2048 0.0 1129.0 Lactobacillaceae proS GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iJN678.proS,iUTI89_1310.UTI89_C0210 Bacteria 1TRBV@1239,3F44A@33958,4H9NN@91061,COG0442@1,COG0442@2 NA|NA|NA J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS PGHMIELC_01270 220668.lp_2049 9.5e-231 805.8 Lactobacillaceae rseP GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107,3.4.21.116 ko:K04771,ko:K06399,ko:K11749,ko:K16922 ko01503,ko02020,ko02024,ko04112,map01503,map02020,map02024,map04112 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1TPMC@1239,3F3TM@33958,4HAQ5@91061,COG0750@1,COG0750@2 NA|NA|NA M zinc metalloprotease PGHMIELC_01271 220668.lp_2050 8.4e-137 493.0 Lactobacillaceae cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1397 Bacteria 1UPNB@1239,3F4AF@33958,4IV81@91061,COG0575@1,COG0575@2 NA|NA|NA I Belongs to the CDS family PGHMIELC_01272 220668.lp_2051 1.8e-147 528.5 Lactobacillaceae uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 Bacteria 1TQTS@1239,3F42M@33958,4HA37@91061,COG0020@1,COG0020@2 NA|NA|NA H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids PGHMIELC_01273 220668.lp_2052 2.5e-82 311.6 Lactobacillaceae frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02838 ko00000,ko03012 Bacteria 1V1F2@1239,3F4X2@33958,4HFSH@91061,COG0233@1,COG0233@2 NA|NA|NA J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another PGHMIELC_01274 220668.lp_2053 2.2e-128 464.9 Lactobacillaceae pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 iSB619.SA_RS06240 Bacteria 1TPXN@1239,3F42J@33958,4H9UB@91061,COG0528@1,COG0528@2 NA|NA|NA F Catalyzes the reversible phosphorylation of UMP to UDP PGHMIELC_01275 220668.lp_2054 1e-151 542.7 Lactobacillaceae tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 ko:K02357 ko00000,ko03012,ko03029 Bacteria 1TPFJ@1239,3F459@33958,4HBDV@91061,COG0264@1,COG0264@2 NA|NA|NA J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome PGHMIELC_01276 220668.lp_2055 6.5e-145 520.0 Lactobacillaceae rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPNA@1239,3F3M1@33958,4H9N5@91061,COG0052@1,COG0052@2 NA|NA|NA J Belongs to the universal ribosomal protein uS2 family PGHMIELC_01277 220668.lp_2056 4.7e-134 483.8 Lactobacillaceae ko:K07025 ko00000 Bacteria 1V5P7@1239,3F5CR@33958,4HHGY@91061,COG1011@1,COG1011@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase PGHMIELC_01278 220668.lp_2057 2.3e-187 661.4 Lactobacillaceae ldhA 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3F4US@33958,4HCIS@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family PGHMIELC_01279 220668.lp_2058 2e-49 201.4 Lactobacillaceae yazA ko:K07461 ko00000 Bacteria 1VEZF@1239,3F7G2@33958,4HNHJ@91061,COG2827@1,COG2827@2 NA|NA|NA L GIY-YIG catalytic domain protein PGHMIELC_01280 220668.lp_2059 1.4e-136 492.3 Lactobacillaceae yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 ko00000,ko01000,ko03016 Bacteria 1TQ25@1239,3F4C5@33958,4HA8W@91061,COG4123@1,COG4123@2 NA|NA|NA L Methyltransferase small domain PGHMIELC_01281 220668.lp_2060 6.4e-119 433.3 Lactobacillaceae plsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1U8N2@1239,3F4QB@33958,4HDQR@91061,COG0204@1,COG0204@2 NA|NA|NA I Acyltransferase PGHMIELC_01282 220668.lp_2061 4.3e-33 146.7 Lactobacillaceae yneF ko:K09976 ko00000 Bacteria 1VEJC@1239,3F809@33958,4HKMJ@91061,COG3763@1,COG3763@2 NA|NA|NA S Uncharacterised protein family (UPF0154) PGHMIELC_01283 1136177.KCA1_1750 2.9e-36 157.5 Lactobacillaceae ynzC Bacteria 1VEKJ@1239,3F87S@33958,4HNIB@91061,COG4224@1,COG4224@2 NA|NA|NA S UPF0291 protein PGHMIELC_01284 220668.lp_2063 5.6e-115 420.2 Lactobacillaceae lexA 3.4.21.88 ko:K01356 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 1TQ3H@1239,3F3JG@33958,4HBHA@91061,COG1974@1,COG1974@2 NA|NA|NA K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair PGHMIELC_01285 220668.lp_2066 3.7e-87 327.8 Lactobacillaceae Bacteria 1W3AZ@1239,28UQM@1,2ZGUY@2,3F65Q@33958,4I0YM@91061 NA|NA|NA PGHMIELC_01286 220668.lp_2067 3.9e-215 753.8 Lactobacillaceae mvaS 2.3.3.10 ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR4K@1239,3F425@33958,4HA67@91061,COG3425@1,COG3425@2 NA|NA|NA I Hydroxymethylglutaryl-CoA synthase PGHMIELC_01287 220668.lp_2068 1.1e-76 292.4 Lactobacillaceae Bacteria 1U5V3@1239,29NYQ@1,309WT@2,3F6IY@33958,4IFIQ@91061 NA|NA|NA PGHMIELC_01288 220668.lp_2069 1.3e-66 258.8 Lactobacillaceae Bacteria 1U6QT@1239,29IMR@1,305J0@2,3F8BS@33958,4IGI3@91061 NA|NA|NA PGHMIELC_01289 220668.lp_2071 3.4e-177 627.5 Lactobacillaceae csbB 2.4.1.83 ko:K00721,ko:K20534 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003,ko01005,ko02000 4.D.2.1.9 GT2 Bacteria 1UI5W@1239,3FBSD@33958,4ISEQ@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 PGHMIELC_01290 220668.lp_2074 2.1e-100 371.7 Lactobacillaceae ko:K07483,ko:K07497 ko00000 Bacteria 1V1QC@1239,3F5BG@33958,4HH7E@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain PGHMIELC_01291 220668.lp_2075 2.1e-221 774.6 Lactobacillaceae lytR5 Bacteria 1TQ9C@1239,3F5ZN@33958,4HB29@91061,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-related transcriptional attenuator domain PGHMIELC_01292 220668.lp_2076 7.9e-143 513.1 Lactobacillaceae ko:K02049 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1TRM6@1239,3FC3E@33958,4HF9R@91061,COG1116@1,COG1116@2 NA|NA|NA P ATPases associated with a variety of cellular activities PGHMIELC_01293 220668.lp_2077 1.2e-260 905.2 Lactobacillaceae opuAB ko:K02050 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1TRRR@1239,3F4E8@33958,4HEN6@91061,COG4986@1,COG4986@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component PGHMIELC_01294 220668.lp_2077 4.1e-42 177.2 Lactobacillaceae opuAB ko:K02050 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1TRRR@1239,3F4E8@33958,4HEN6@91061,COG4986@1,COG4986@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component PGHMIELC_01295 220668.lp_2078 4.5e-230 803.5 Lactobacillaceae rodA ko:K05837 ko00000,ko03036 Bacteria 1TPGH@1239,3F9D5@33958,4HAV4@91061,COG0772@1,COG0772@2 NA|NA|NA D Cell cycle protein PGHMIELC_01297 565653.EGBG_00519 1.5e-36 160.6 Firmicutes 2.7.7.1,3.6.1.55 ko:K03574,ko:K13522 ko00760,ko01100,map00760,map01100 R00137,R03005 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 1V7T8@1239,COG1051@1,COG1051@2 NA|NA|NA F Hydrolase, nudix family PGHMIELC_01299 220668.lp_2081 1.6e-31 141.4 Lactobacillaceae Bacteria 1U6X5@1239,29PQN@1,30ANU@2,3F8NG@33958,4IGRE@91061 NA|NA|NA PGHMIELC_01300 220668.lp_2082 5.8e-143 513.5 Lactobacillaceae Bacteria 1TSAZ@1239,3F4S0@33958,4HIIG@91061,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase PGHMIELC_01301 220668.lp_2083 8.5e-57 226.1 Lactobacillaceae ybjQ Bacteria 1VADM@1239,3F6YC@33958,4HKGZ@91061,COG0393@1,COG0393@2 NA|NA|NA S Belongs to the UPF0145 family PGHMIELC_01302 220668.lp_2084 7.2e-212 743.0 Lactobacillaceae Bacteria 1UG5D@1239,2ZBIK@2,3FBS8@33958,4H9W5@91061,COG0477@1 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_01303 220668.lp_2085 1e-102 379.4 Lactobacillaceae Bacteria 1VZ80@1239,3F74V@33958,4IFVN@91061,COG0640@1,COG0640@2 NA|NA|NA K Helix-turn-helix domain PGHMIELC_01304 220668.lp_2086 2.9e-93 347.8 Lactobacillaceae apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816,ko:K09685 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko03000,ko04147 Bacteria 1V1BV@1239,3F4DB@33958,4HFUA@91061,COG0503@1,COG0503@2 NA|NA|NA F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis PGHMIELC_01305 220668.lp_2087 0.0 1495.7 Lactobacillaceae recJ ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPXE@1239,3F42C@33958,4H9UP@91061,COG0608@1,COG0608@2,COG4199@1,COG4199@2 NA|NA|NA L Single-stranded-DNA-specific exonuclease RecJ PGHMIELC_01306 220668.lp_2088 2e-50 204.9 Lactobacillaceae yrvD ko:K08992 ko00000 Bacteria 1VIG5@1239,3F7IW@33958,4HP5V@91061,COG5416@1,COG5416@2 NA|NA|NA S Lipopolysaccharide assembly protein A domain PGHMIELC_01307 220668.lp_2089 1.5e-138 498.8 Lactobacillaceae XK27_05435 1.1.1.100 ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TSJ3@1239,3F41Y@33958,4HI3D@91061,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family PGHMIELC_01308 220668.lp_2090 2.8e-179 634.4 Lactobacillaceae rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 1TRGP@1239,3F4F1@33958,4HABM@91061,COG1234@1,COG1234@2 NA|NA|NA J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA PGHMIELC_01309 220668.lp_2093 3.2e-46 190.7 Lactobacillaceae Bacteria 1U6B4@1239,2A5F6@1,30U54@2,3F7HU@33958,4IG2N@91061 NA|NA|NA PGHMIELC_01310 220668.lp_2094 2.4e-245 854.4 Lactobacillaceae obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043021,GO:0043022,GO:0043167,GO:0043168,GO:0043934,GO:0044424,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03979 ko00000,ko01000,ko03009 Bacteria 1TPX7@1239,3F4ZA@33958,4H9P8@91061,COG0536@1,COG0536@2 NA|NA|NA S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control PGHMIELC_01311 220668.lp_2095 1.5e-135 488.8 Lactobacillaceae fruR ko:K03436 ko00000,ko03000 Bacteria 1TSF8@1239,3F3JB@33958,4HDT9@91061,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain PGHMIELC_01312 220668.lp_2096 1.8e-170 605.1 Lactobacillaceae pfkB 2.7.1.11,2.7.1.56 ko:K00882,ko:K16370 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00345 R00756,R02071,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ36@1239,3F3SG@33958,4HANU@91061,COG1105@1,COG1105@2 NA|NA|NA H Belongs to the carbohydrate kinase PfkB family. LacC subfamily PGHMIELC_01313 220668.lp_2097 6.7e-292 1009.6 Lactobacillaceae fruA 2.7.1.194,2.7.1.200,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K11201 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00306,M00550 R03232,R05570,R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.5.1,4.A.7.1 Bacteria 1TPKU@1239,3F44C@33958,4H9KR@91061,COG1299@1,COG1299@2,COG1445@1,COG1445@2,COG1762@1,COG1762@2 NA|NA|NA GT Phosphotransferase System PGHMIELC_01314 220668.lp_2098 9.5e-250 869.0 Lactobacillaceae cpdA Bacteria 1UQCQ@1239,3FC19@33958,4HE2R@91061,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase PGHMIELC_01315 220668.lp_2099 1.4e-262 911.8 Lactobacillaceae cps4J Bacteria 1TRRI@1239,3F47P@33958,4IEU9@91061,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein PGHMIELC_01316 220668.lp_2100 1.7e-176 625.2 Lactobacillaceae cps4I Bacteria 1UZYU@1239,3F6ND@33958,4HQ2D@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 PGHMIELC_01317 220668.lp_2101 1.6e-233 815.1 Lactobacillaceae Bacteria 1U7PF@1239,2AHJR@1,317XH@2,3F9ZB@33958,4IHKS@91061 NA|NA|NA PGHMIELC_01318 220668.lp_2102 2.9e-190 671.0 Lactobacillaceae cps4G Bacteria 1V369@1239,3F64A@33958,4HI0I@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 PGHMIELC_01319 220668.lp_2103 1.2e-202 712.2 Lactobacillaceae cps4F 2.4.1.21,2.4.1.306 ko:K00703,ko:K00754,ko:K21365 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT4,GT5 Bacteria 1UHSF@1239,3F428@33958,4HB04@91061,COG0297@1,COG0297@2,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 PGHMIELC_01320 220668.lp_2104 7.9e-128 463.0 Lactobacillaceae tuaA Bacteria 1TP7M@1239,3F5PC@33958,4HB15@91061,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase PGHMIELC_01321 220668.lp_2105 9.6e-180 636.0 Lactobacillaceae cps4D 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS00780 Bacteria 1V34Y@1239,3F5GY@33958,4HCJE@91061,COG0451@1,COG0451@2 NA|NA|NA M RmlD substrate binding domain PGHMIELC_01322 220668.lp_2106 3.5e-146 524.2 Lactobacillaceae ywqE 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1TQ1T@1239,3F3RT@33958,4HDZR@91061,COG4464@1,COG4464@2 NA|NA|NA GM PHP domain protein PGHMIELC_01323 220668.lp_2107 7.3e-124 449.9 Lactobacillaceae ywqD 2.7.10.1 ko:K08252,ko:K16554 ko05111,map05111 ko00000,ko00001,ko01000,ko02000 8.A.3.1 Bacteria 1TS4R@1239,3F4BM@33958,4HCEN@91061,COG0489@1,COG0489@2 NA|NA|NA D Capsular exopolysaccharide family PGHMIELC_01324 220668.lp_2108 1.1e-125 456.1 Lactobacillaceae epsB Bacteria 1UZCR@1239,3F4M5@33958,4HE26@91061,COG3944@1,COG3944@2 NA|NA|NA M biosynthesis protein PGHMIELC_01325 220668.lp_2109 0.0 1199.1 Lactobacillaceae uvrC ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TP4B@1239,3F3MY@33958,4H9QH@91061,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision PGHMIELC_01326 220668.lp_2110 1.3e-134 485.7 Lactobacillaceae glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein PGHMIELC_01327 220668.lp_2111 9.2e-270 935.6 Lactobacillaceae glnPH2 ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TPM3@1239,3F48Y@33958,4HAS2@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2 NA|NA|NA P ABC transporter permease PGHMIELC_01328 220668.lp_2112 4.3e-22 109.8 Lactobacillaceae Bacteria 1U8BD@1239,2BSM8@1,32MPT@2,3FASU@33958,4II9D@91061 NA|NA|NA PGHMIELC_01329 220668.lp_2113 9.9e-73 279.3 Lactobacillaceae Bacteria 1VY7K@1239,2F916@1,341CT@2,3F70S@33958,4HX4B@91061 NA|NA|NA S Iron-sulphur cluster biosynthesis PGHMIELC_01330 220668.lp_2114 2.2e-49 201.4 Lactobacillaceae MA20_27270 Bacteria 1VIQA@1239,3F6WJ@33958,4HM6C@91061,COG1694@1,COG1694@2 NA|NA|NA S mazG nucleotide pyrophosphohydrolase PGHMIELC_01331 220668.lp_2115 5.1e-110 403.7 Lactobacillaceae engB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03978 ko00000,ko03036 Bacteria 1TSPW@1239,3F44G@33958,4HBXZ@91061,COG0218@1,COG0218@2 NA|NA|NA D Necessary for normal cell division and for the maintenance of normal septation PGHMIELC_01332 220668.lp_2116 3.3e-236 823.9 Lactobacillaceae clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 1TQ00@1239,3F41K@33958,4H9U4@91061,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP PGHMIELC_01333 220668.lp_2118 4.1e-213 747.3 Lactobacillaceae tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K03545 ko00000 Bacteria 1TQQ8@1239,3F40B@33958,4H9Q8@91061,COG0544@1,COG0544@2 NA|NA|NA D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase PGHMIELC_01334 220668.lp_2119 6.1e-224 783.1 Lactobacillaceae tuf ko:K02358,ko:K15771 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 Bacteria 1TPKC@1239,3F3ZP@33958,4HAEH@91061,COG0050@1,COG0050@2 NA|NA|NA J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis PGHMIELC_01335 220668.lp_2121 9.1e-159 566.2 Lactobacillaceae Bacteria 1VWCF@1239,3F6E0@33958,4HWSW@91061,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat PGHMIELC_01336 220668.lp_2122 0.0 1123.2 Lactobacillaceae rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TQ9G@1239,3F3U9@33958,4HAAP@91061,COG0595@1,COG0595@2 NA|NA|NA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay PGHMIELC_01337 220668.lp_2123 6.2e-157 560.1 Lactobacillaceae dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCK@1239,3F4UH@33958,4H9K9@91061,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) PGHMIELC_01338 220668.lp_2124 2e-190 671.8 Lactobacillaceae mdtG GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085 ko:K08161 ko00000,ko02000 2.A.1.2.20 Bacteria 1U5GG@1239,3F5VM@33958,4IF7B@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major Facilitator Superfamily PGHMIELC_01339 1136177.KCA1_1802 6e-42 176.4 Lactobacillaceae rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VA5C@1239,3F7DV@33958,4HKE9@91061,COG0184@1,COG0184@2 NA|NA|NA J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome PGHMIELC_01340 220668.lp_2126 1.5e-34 151.8 Lactobacillaceae rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02968 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEGX@1239,3F7D8@33958,4HNJS@91061,COG0268@1,COG0268@2 NA|NA|NA J Binds directly to 16S ribosomal RNA PGHMIELC_01341 220668.lp_2128 4.8e-188 663.7 Lactobacillaceae holA 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TRM0@1239,3F3TP@33958,4HBB4@91061,COG1466@1,COG1466@2 NA|NA|NA L DNA polymerase III delta subunit PGHMIELC_01342 220668.lp_2129 0.0 1432.2 Lactobacillaceae comEC ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1TS9U@1239,3F3VT@33958,4H9M4@91061,COG0658@1,COG0658@2,COG2333@1,COG2333@2 NA|NA|NA S Competence protein ComEC PGHMIELC_01343 220668.lp_2130 6.4e-79 300.1 Lactobacillaceae comEB 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 Bacteria 1V3PU@1239,3F6BF@33958,4HCDG@91061,COG2131@1,COG2131@2 NA|NA|NA F ComE operon protein 2 PGHMIELC_01344 220668.lp_2131 4.7e-126 457.2 Lactobacillaceae comEA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K01991,ko:K02237 ko02026,map02026 M00429 ko00000,ko00001,ko00002,ko02000,ko02044 1.B.18,3.A.11.1,3.A.11.2 Bacteria 1VA3W@1239,3F7NP@33958,4HKJ1@91061,COG1555@1,COG1555@2,COG1596@1,COG1596@2 NA|NA|NA L Competence protein ComEA PGHMIELC_01345 220668.lp_2132 9.6e-197 692.6 Lactobacillaceae ylbL ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Bacteria 1TRUF@1239,3F4KY@33958,4HBAY@91061,COG3480@1,COG3480@2 NA|NA|NA T Belongs to the peptidase S16 family PGHMIELC_01346 220668.lp_2133 1.4e-84 318.9 Lactobacillaceae coaD GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0015939,GO:0015940,GO:0016043,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046390,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 iPC815.YPO0053,iSDY_1059.SDY_4064 Bacteria 1V3MR@1239,3F6YS@33958,4HH47@91061,COG0669@1,COG0669@2 NA|NA|NA H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate PGHMIELC_01347 220668.lp_2134 7.7e-100 369.8 Lactobacillaceae rsmD 2.1.1.171 ko:K08316 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1V3JF@1239,3F505@33958,4HGXT@91061,COG0742@1,COG0742@2 NA|NA|NA L RNA methyltransferase, RsmD family PGHMIELC_01348 220668.lp_2135 1.5e-49 201.8 Bacteria ylbG Bacteria COG4471@1,COG4471@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2129) PGHMIELC_01349 220668.lp_2136 0.0 2275.0 Lactobacillaceae pyc GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHP9@1239,3F4U7@33958,4IS56@91061,COG1038@1,COG1038@2 NA|NA|NA C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second PGHMIELC_01350 220668.lp_2137 1.6e-205 721.8 Lactobacillaceae ftsW ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 2.A.103.1 Bacteria 1TPT7@1239,3F4IK@33958,4HAEV@91061,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family PGHMIELC_01351 220668.lp_2141 1.4e-292 1011.5 Lactobacillaceae Bacteria 1VAQX@1239,2DQSR@1,338EM@2,3FBTQ@33958,4HM5B@91061 NA|NA|NA PGHMIELC_01352 220668.lp_2142 5.1e-259 899.8 Lactobacillaceae ica2 ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.1.1.2,4.D.1.1.3 GT2 Bacteria 1TR2P@1239,3F53W@33958,4HAQN@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family group 2 PGHMIELC_01353 220668.lp_2143 1.2e-103 382.5 Lactobacillaceae Bacteria 1V5MF@1239,290YK@1,2ZNKB@2,3F5RH@33958,4HX21@91061 NA|NA|NA PGHMIELC_01354 220668.lp_2145 1.1e-197 696.0 Lactobacillaceae Bacteria 1UFIP@1239,2BCCC@1,325XR@2,3F3X6@33958,4IESV@91061 NA|NA|NA PGHMIELC_01355 220668.lp_2146 0.0 1204.9 Lactobacillaceae typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 ko:K06207 ko00000 Bacteria 1TQ5Y@1239,3F3UK@33958,4HAQ6@91061,COG1217@1,COG1217@2 NA|NA|NA T GTP-binding protein TypA PGHMIELC_01356 220668.lp_2147 6.3e-137 493.4 Lactobacillaceae suhB 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR4E@1239,3F5BB@33958,4HB92@91061,COG0483@1,COG0483@2 NA|NA|NA G Belongs to the inositol monophosphatase superfamily PGHMIELC_01357 220668.lp_2149 3.3e-46 190.7 Lactobacillaceae yktA ko:K16509 ko00000 Bacteria 1VEK8@1239,3F80A@33958,4HNKR@91061,COG4476@1,COG4476@2 NA|NA|NA S Belongs to the UPF0223 family PGHMIELC_01358 220668.lp_2150 4.7e-163 580.5 Lactobacillaceae 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1UFQZ@1239,3F4RQ@33958,4IEWQ@91061,COG0039@1,COG0039@2 NA|NA|NA C L-malate dehydrogenase activity PGHMIELC_01359 220668.lp_2151 1.2e-266 925.2 Lactobacillaceae lpdA GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006103,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006520,GO:0006544,GO:0006546,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015036,GO:0016054,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017144,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019464,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0036211,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045250,GO:0045252,GO:0045254,GO:0046390,GO:0046395,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0097159,GO:0106077,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 iAPECO1_1312.APECO1_1869,iEcolC_1368.EcolC_3543,iPC815.YPO3417,iSFV_1184.SFV_0107,iUMN146_1321.UM146_23385 Bacteria 1TP1W@1239,3F426@33958,4HB3K@91061,COG1249@1,COG1249@2 NA|NA|NA C Dehydrogenase PGHMIELC_01360 220668.lp_2152 1.8e-208 731.9 Lactobacillaceae pdhC 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TR5N@1239,3F3RR@33958,4HA7A@91061,COG0508@1,COG0508@2 NA|NA|NA C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex PGHMIELC_01361 1136177.KCA1_1824 4.5e-180 637.1 Lactobacillaceae pdhB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944,GO:0140030,GO:0140032 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2496c,iYO844.BSU14590 Bacteria 1TP3J@1239,3F4RV@33958,4HA4H@91061,COG0022@1,COG0022@2 NA|NA|NA C Transketolase, C-terminal domain protein PGHMIELC_01362 220668.lp_2154 3.6e-210 737.3 Lactobacillaceae pdhA 1.2.4.1,1.2.4.4 ko:K00161,ko:K00166 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TQDG@1239,3F3JK@33958,4H9PQ@91061,COG1071@1,COG1071@2 NA|NA|NA C Dehydrogenase E1 component PGHMIELC_01363 220668.lp_2155 9e-101 372.9 Lactobacillaceae def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 ko:K01450,ko:K01462 ko00270,ko00630,map00270,map00630 R00653 RC00165,RC00323 ko00000,ko00001,ko01000 Bacteria 1V70B@1239,3F3YH@33958,4HH0G@91061,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions PGHMIELC_01364 220668.lp_2156 1.6e-85 322.0 Lactobacillaceae Bacteria 1VQPI@1239,2C389@1,2ZQCN@2,3F79N@33958,4I0G9@91061 NA|NA|NA PGHMIELC_01365 220668.lp_2157 3.1e-33 147.1 Lactobacillaceae ykzG Bacteria 1VEI7@1239,3F807@33958,4HNSK@91061,COG5503@1,COG5503@2 NA|NA|NA S Belongs to the UPF0356 family PGHMIELC_01366 220668.lp_2158 0.0 1107.4 Lactobacillaceae rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TQ9G@1239,3F3TT@33958,4HAAP@91061,COG0595@1,COG0595@2 NA|NA|NA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay PGHMIELC_01367 220668.lp_2159 5.7e-188 663.3 Lactobacillaceae ytlR 2.7.1.91 ko:K04718 ko00600,ko01100,ko04020,ko04071,ko04072,ko04370,ko04371,ko04666,ko05152,map00600,map01100,map04020,map04071,map04072,map04370,map04371,map04666,map05152 M00100 R01926,R02976 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V7DZ@1239,3F5GQ@33958,4HBUD@91061,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain PGHMIELC_01368 220668.lp_2160 1.7e-28 131.3 Lactobacillaceae Bacteria 1U6IE@1239,29PG6@1,30ADU@2,3F7Z6@33958,4IGAR@91061 NA|NA|NA PGHMIELC_01369 220668.lp_2162 4.1e-108 398.7 Lactobacillaceae mltD ko:K08307,ko:K12204,ko:K19224,ko:K21471 ko00000,ko01000,ko01002,ko01011,ko02044 3.A.7.10.1,3.A.7.9.1 CBM50 Bacteria 1VG0Z@1239,3F50V@33958,4HBE9@91061,COG0791@1,COG0791@2,COG1388@1,COG1388@2 NA|NA|NA M NlpC P60 family protein PGHMIELC_01370 220668.lp_2166 4.4e-172 610.5 Lactobacillaceae prs 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2848 Bacteria 1TQ6Q@1239,3FCBW@33958,4HV42@91061,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) PGHMIELC_01371 220668.lp_2168 0.0 1630.2 Lactobacillaceae recD2 3.1.11.5 ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPZH@1239,3F44X@33958,4HATQ@91061,COG0507@1,COG0507@2 NA|NA|NA L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity PGHMIELC_01372 220668.lp_2169 3.6e-120 437.6 Lactobacillaceae Bacteria 1VFGR@1239,3F4MD@33958,4IBSH@91061,COG0457@1,COG0457@2 NA|NA|NA S Repeat protein PGHMIELC_01373 220668.lp_2170 5.5e-121 440.3 Lactobacillaceae pgm6 5.4.2.11,5.4.2.12 ko:K01834,ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1V6ES@1239,3F3U3@33958,4HGZI@91061,COG0406@1,COG0406@2 NA|NA|NA G phosphoglycerate mutase PGHMIELC_01374 220668.lp_2173 3.8e-268 930.2 Lactobacillaceae Bacteria 1U5AN@1239,3F5E8@33958,4IF23@91061,COG5492@1,COG5492@2 NA|NA|NA N domain, Protein PGHMIELC_01375 220668.lp_2174 1.7e-193 681.8 Lactobacillaceae Bacteria 1VFEV@1239,3F470@33958,4HPF3@91061,COG4072@1,COG4072@2 NA|NA|NA S Bacterial protein of unknown function (DUF916) PGHMIELC_01376 220668.lp_2175 2.3e-120 438.3 Lactobacillaceae Bacteria 1W54S@1239,3F5H0@33958,4IF30@91061,COG5492@1,COG5492@2 NA|NA|NA N WxL domain surface cell wall-binding PGHMIELC_01377 220668.lp_2176 2.6e-115 421.4 Lactobacillaceae ktrA ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1TQ9H@1239,3F5G0@33958,4HBPH@91061,COG0569@1,COG0569@2 NA|NA|NA P domain protein PGHMIELC_01378 220668.lp_2177 1.3e-241 842.0 Lactobacillaceae ktrB ko:K03498 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1TQ4S@1239,3F5BE@33958,4H9ME@91061,COG0168@1,COG0168@2 NA|NA|NA P Potassium uptake protein PGHMIELC_01379 220668.lp_2178 9e-225 785.8 Lactobacillaceae mnmA GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 Bacteria 1TPIZ@1239,3F4N5@33958,4HBJ6@91061,COG0482@1,COG0482@2 NA|NA|NA J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 PGHMIELC_01380 220668.lp_2179 4.9e-57 226.9 Lactobacillaceae XK27_04120 Bacteria 1VDSF@1239,2DHWG@1,32U9W@2,3F7E3@33958,4HP9N@91061 NA|NA|NA S Putative amino acid metabolism PGHMIELC_01381 220668.lp_2180 7.1e-217 759.6 Lactobacillaceae iscS 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TP21@1239,3F3RF@33958,4HA6H@91061,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class V PGHMIELC_01382 220668.lp_2181 1.8e-122 445.3 Lactobacillaceae mtnN 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 Bacteria 1U7WK@1239,3F4HE@33958,4HB8K@91061,COG0775@1,COG0775@2 NA|NA|NA E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively PGHMIELC_01383 220668.lp_2182 4.6e-28 130.2 Lactobacillaceae Bacteria 1U6XV@1239,2DKSR@1,30AP7@2,3F8PI@33958,4IGS4@91061 NA|NA|NA PGHMIELC_01384 220668.lp_2183 1.9e-95 355.1 Lactobacillaceae nudF 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 iHN637.CLJU_RS05505,iSB619.SA_RS07540,iYO844.BSU23610 Bacteria 1V6F5@1239,3F53J@33958,4HII9@91061,COG0494@1,COG0494@2 NA|NA|NA L ADP-ribose pyrophosphatase PGHMIELC_01385 220668.lp_2185 7e-189 666.4 Lactobacillaceae dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMN@1239,3F4F7@33958,4HBH4@91061,COG0253@1,COG0253@2 NA|NA|NA E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan PGHMIELC_01386 1267003.KB911374_gene828 9e-18 96.7 Lactobacillaceae Bacteria 1TVW9@1239,2B88Q@1,321HB@2,3F92J@33958,4I4GY@91061 NA|NA|NA S Protein of unknown function (DUF3021) PGHMIELC_01387 1122147.AUEH01000037_gene136 2.9e-36 158.3 Lactobacillaceae Bacteria 1W04J@1239,3F6TA@33958,4HRMI@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain PGHMIELC_01388 1154757.Q5C_02675 3.6e-80 305.1 Leuconostocaceae cylB ko:K11051 ko02010,map02010 M00298 ko00000,ko00001,ko00002,ko02000 3.A.1.130 Bacteria 1TSH0@1239,4AXTJ@81850,4HJK7@91061,COG0842@1,COG0842@2 NA|NA|NA U ABC-2 type transporter PGHMIELC_01389 699248.SRA_00473 8.8e-79 300.4 Bacilli cylA ko:K01990,ko:K11050 ko02010,map02010 M00254,M00298 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.130 Bacteria 1V0AH@1239,4HD15@91061,COG1131@1,COG1131@2 NA|NA|NA V abc transporter atp-binding protein PGHMIELC_01390 220668.lp_2187 0.0 1904.4 Lactobacillaceae ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_0027,iPC815.YPO0475 Bacteria 1TPS7@1239,3F3X4@33958,4HAWB@91061,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) PGHMIELC_01391 220668.lp_2189 1.2e-86 326.2 Lactobacillaceae divIVA ko:K04074 ko00000,ko03036 Bacteria 1V27M@1239,3F4IN@33958,4HG80@91061,COG3599@1,COG3599@2 NA|NA|NA D DivIVA domain protein PGHMIELC_01392 220668.lp_2190 3.4e-146 524.2 Lactobacillaceae ylmH ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 Bacteria 1U5V2@1239,3F48W@33958,4HD3F@91061,COG2302@1,COG2302@2 NA|NA|NA S S4 domain protein PGHMIELC_01393 220668.lp_2191 1.2e-36 158.7 Lactobacillaceae yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02221 ko00000,ko02044 Bacteria 1VEKA@1239,3F843@33958,4HNJR@91061,COG0762@1,COG0762@2 NA|NA|NA S YGGT family PGHMIELC_01394 220668.lp_2192 3.3e-71 274.2 Lactobacillaceae sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0044464,GO:0051301,GO:0071840,GO:0071944,GO:0090529 ko:K09772 ko00000,ko03036 Bacteria 1VER3@1239,3F7MQ@33958,4HKIC@91061,COG1799@1,COG1799@2 NA|NA|NA D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA PGHMIELC_01395 220668.lp_2193 1.4e-229 802.0 Lactobacillaceae ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Bacteria 1TP6W@1239,3F4V1@33958,4H9WZ@91061,COG0206@1,COG0206@2 NA|NA|NA D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity PGHMIELC_01396 220668.lp_2194 5.5e-245 853.2 Lactobacillaceae ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Bacteria 1TP1Z@1239,3F413@33958,4H9NF@91061,COG0849@1,COG0849@2 NA|NA|NA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring PGHMIELC_01397 220668.lp_2195 5.8e-163 580.1 Lactobacillaceae divIB ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Bacteria 1V6V5@1239,3F406@33958,4HDFD@91061,COG1589@1,COG1589@2 NA|NA|NA D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex PGHMIELC_01398 220668.lp_2196 1.5e-197 695.3 Lactobacillaceae murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 GT28 iLJ478.TM0232,iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089 Bacteria 1TQFT@1239,3F4FW@33958,4HBAQ@91061,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) PGHMIELC_01399 220668.lp_2197 1.2e-260 905.2 Lactobacillaceae murD 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TQ3P@1239,3F49W@33958,4HA5P@91061,COG0771@1,COG0771@2 NA|NA|NA M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) PGHMIELC_01400 220668.lp_2199 8.3e-179 632.9 Lactobacillaceae mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Bacteria 1TP8W@1239,3F3YP@33958,4H9TP@91061,COG0472@1,COG0472@2 NA|NA|NA M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan PGHMIELC_01401 220668.lp_2200 0.0 1355.1 Lactobacillaceae ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 1TP93@1239,3F47N@33958,4H9VQ@91061,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein PGHMIELC_01402 220668.lp_2201 7.5e-54 216.5 Lactobacillaceae ftsL Bacteria 1VCE5@1239,3F6KG@33958,4HM4W@91061,COG4839@1,COG4839@2 NA|NA|NA D Cell division protein FtsL PGHMIELC_01403 220668.lp_2202 1.9e-175 621.7 Lactobacillaceae rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 1TNZV@1239,3F3MF@33958,4H9U2@91061,COG0275@1,COG0275@2 NA|NA|NA J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA PGHMIELC_01404 220668.lp_2203 1.9e-77 295.0 Lactobacillaceae mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 ko:K03925 ko00000 Bacteria 1V3JD@1239,3F6K3@33958,4HH23@91061,COG2001@1,COG2001@2 NA|NA|NA K Belongs to the MraZ family PGHMIELC_01405 220668.lp_2205 1.9e-62 245.0 Lactobacillaceae Bacteria 1TVPU@1239,2DIRP@1,3040A@2,3F6RY@33958,4IFNU@91061 NA|NA|NA S Protein of unknown function (DUF3397) PGHMIELC_01406 220668.lp_2206 2.1e-174 618.2 Lactobacillaceae corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1TPI8@1239,3F5FV@33958,4HE7S@91061,COG0598@1,COG0598@2 NA|NA|NA P CorA-like Mg2+ transporter protein PGHMIELC_01407 220668.lp_2210 0.0 1347.0 Lactobacillaceae ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K03466 ko00000,ko03036 3.A.12 Bacteria 1TPJR@1239,3F3JZ@33958,4H9WA@91061,COG1674@1,COG1674@2 NA|NA|NA D Belongs to the FtsK SpoIIIE SftA family PGHMIELC_01408 220668.lp_2211 4.5e-94 350.5 Lactobacillaceae trmL GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 ko:K03216 ko00000,ko01000,ko03016 Bacteria 1V3GW@1239,3F42Y@33958,4HFNY@91061,COG0219@1,COG0219@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily PGHMIELC_01409 220668.lp_2212 7e-113 413.3 Lactobacillaceae ywnB ko:K07118 ko00000 Bacteria 1TZ3T@1239,3F5K7@33958,4HVUN@91061,COG2910@1,COG2910@2 NA|NA|NA S NAD(P)H-binding PGHMIELC_01410 220668.lp_2213 9.8e-210 736.1 Lactobacillaceae brnQ GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 ko:K03311 ko00000 2.A.26 iSB619.SA_RS01075 Bacteria 1TQIS@1239,3F3KC@33958,4HAKA@91061,COG1114@1,COG1114@2 NA|NA|NA U Component of the transport system for branched-chain amino acids PGHMIELC_01412 220668.lp_2215 1.1e-161 575.9 Lactobacillaceae rrmA 2.1.1.187 ko:K00563,ko:K10947 R07233 RC00003 ko00000,ko01000,ko03000,ko03009 Bacteria 1V1WE@1239,3F4U3@33958,4HGQ9@91061,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase PGHMIELC_01413 220668.lp_2216 1.7e-41 174.9 Lactobacillaceae rpsN GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEF6@1239,3F7KX@33958,4HKK1@91061,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site PGHMIELC_01414 220668.lp_2217 8.1e-205 719.5 Lactobacillaceae XK27_05220 Bacteria 1TQ84@1239,3F418@33958,4H9SR@91061,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter PGHMIELC_01415 220668.lp_2218 3.9e-57 227.3 Lactobacillaceae srlB 2.7.1.198 ko:K02781 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 Bacteria 1VGKB@1239,3F8EZ@33958,4HNJN@91061,COG3731@1,COG3731@2 NA|NA|NA G PTS system glucitol/sorbitol-specific IIA component PGHMIELC_01416 220668.lp_2219 7.4e-194 682.9 Lactobacillaceae pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ3J@1239,3F3RC@33958,4HBHB@91061,COG2706@1,COG2706@2 NA|NA|NA G Lactonase, 7-bladed beta-propeller PGHMIELC_01417 220668.lp_2220 5.1e-116 423.7 Lactobacillaceae cutC GO:0006873,GO:0006875,GO:0006878,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0019725,GO:0030003,GO:0042221,GO:0042592,GO:0046688,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 ko:K06201 ko00000 Bacteria 1TQYI@1239,3F4NZ@33958,4HE1E@91061,COG3142@1,COG3142@2 NA|NA|NA P Participates in the control of copper homeostasis PGHMIELC_01418 220668.lp_2221 8.9e-175 619.4 Lactobacillaceae rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1TS1T@1239,3F4AU@33958,4HBRY@91061,COG0564@1,COG0564@2 NA|NA|NA G Responsible for synthesis of pseudouridine from uracil PGHMIELC_01419 220668.lp_2222 4.7e-151 540.4 Lactobacillaceae nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895 Bacteria 1TRB3@1239,3F45D@33958,4HB08@91061,COG0061@1,COG0061@2 NA|NA|NA F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP PGHMIELC_01420 220668.lp_2223 2.7e-120 438.0 Lactobacillaceae yjbM 2.7.6.5 ko:K07816 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 1TQ2F@1239,3F452@33958,4HA3Q@91061,COG2357@1,COG2357@2 NA|NA|NA S RelA SpoT domain protein PGHMIELC_01421 220668.lp_2224 3.6e-114 417.5 Lactobacillaceae yjbH GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 Bacteria 1TQ8K@1239,3F6QR@33958,4HAI8@91061,COG2761@1,COG2761@2 NA|NA|NA Q Thioredoxin PGHMIELC_01422 220668.lp_2225 0.0 1120.9 Lactobacillaceae pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 ko:K08602 ko00000,ko01000,ko01002 Bacteria 1TP4P@1239,3F4E5@33958,4HA7X@91061,COG1164@1,COG1164@2 NA|NA|NA E oligoendopeptidase F PGHMIELC_01423 220668.lp_2226 8.1e-207 726.1 Lactobacillaceae coiA 3.6.4.12 ko:K03657,ko:K06198 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TRGD@1239,3F4BZ@33958,4HFP5@91061,COG4469@1,COG4469@2 NA|NA|NA S Competence protein PGHMIELC_01424 220668.lp_2227 2.2e-131 474.9 Lactobacillaceae mecA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K16511 ko00000 Bacteria 1UZ7D@1239,3F5G4@33958,4HID6@91061,COG4862@1,COG4862@2 NA|NA|NA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis PGHMIELC_01425 220668.lp_2228 2.7e-67 261.2 Lactobacillaceae spxA 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1V3QC@1239,3F6HJ@33958,4HH0I@91061,COG1393@1,COG1393@2 NA|NA|NA K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress PGHMIELC_01426 220668.lp_2229 1.1e-138 499.2 Lactobacillaceae yhfI GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 Bacteria 1V1TF@1239,3F4U0@33958,4HFNV@91061,COG1234@1,COG1234@2 NA|NA|NA S Metallo-beta-lactamase superfamily PGHMIELC_01427 220668.lp_2230 1.3e-90 339.0 Lactobacillaceae traP GO:0005575,GO:0016020 1.14.99.57,6.2.1.3 ko:K01897,ko:K21481 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 1V501@1239,3F3UU@33958,4HHA2@91061,COG2329@1,COG2329@2 NA|NA|NA S enzyme involved in biosynthesis of extracellular polysaccharides PGHMIELC_01428 220668.lp_2231a 3.5e-64 250.8 Lactobacillaceae Bacteria 1U67W@1239,29P79@1,30A5C@2,3F79S@33958,4IFYK@91061 NA|NA|NA PGHMIELC_01429 220668.lp_2231b 1.6e-75 288.5 Lactobacillaceae yugI 5.3.1.9 ko:K01810,ko:K02945,ko:K07570,ko:K07571,ko:K19142 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko03010,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map03010 M00001,M00004,M00114,M00178 R02739,R02740,R03321 RC00376,RC00563 br01610,ko00000,ko00001,ko00002,ko01000,ko02048,ko03011,ko04147 Bacteria 1VASQ@1239,3F6AN@33958,4HKSW@91061,COG1098@1,COG1098@2 NA|NA|NA J general stress protein PGHMIELC_01430 220668.lp_2231c 5.5e-109 400.2 Lactobacillaceae ppiB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03768 ko00000,ko01000,ko03110 Bacteria 1TRHW@1239,3F3TI@33958,4H9V0@91061,COG0652@1,COG0652@2 NA|NA|NA G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides PGHMIELC_01431 220668.lp_2232 3e-119 434.5 Lactobacillaceae dedA ko:K03975 ko00000 Bacteria 1UZ4P@1239,3F4KG@33958,4HG3F@91061,COG0586@1,COG0586@2 NA|NA|NA S SNARE-like domain protein PGHMIELC_01432 220668.lp_2234 3.9e-116 424.1 Lactobacillaceae Bacteria 1V7UW@1239,3F4YP@33958,4HHH4@91061,COG4478@1,COG4478@2 NA|NA|NA S Protein of unknown function (DUF1461) PGHMIELC_01433 220668.lp_2235 1.5e-146 525.4 Lactobacillaceae nagD 2.7.1.25,3.1.3.41 ko:K00860,ko:K01101 ko00230,ko00627,ko00920,ko01100,ko01120,map00230,map00627,map00920,map01100,map01120 M00176 R00509,R03024,R04928 RC00002,RC00078,RC00151 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQGM@1239,3F49D@33958,4HA3R@91061,COG0647@1,COG0647@2 NA|NA|NA G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro PGHMIELC_01434 220668.lp_2236 1.3e-79 302.8 Lactobacillaceae yutD Bacteria 1VA85@1239,3F66P@33958,4HKF7@91061,COG4470@1,COG4470@2 NA|NA|NA S Protein of unknown function (DUF1027) PGHMIELC_01435 220668.lp_2237 8.7e-270 935.6 Lactobacillaceae yunD 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 1TQCW@1239,3F4ZD@33958,4HAUC@91061,COG0737@1,COG0737@2 NA|NA|NA F Belongs to the 5'-nucleotidase family PGHMIELC_01436 220668.lp_2238 2.2e-116 424.9 Lactobacillaceae Bacteria 1V40Y@1239,3F4EX@33958,4HH4J@91061,COG4186@1,COG4186@2 NA|NA|NA S Calcineurin-like phosphoesterase PGHMIELC_01437 220668.lp_2240 5.6e-253 879.8 Lactobacillaceae cycA GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease PGHMIELC_01438 220668.lp_2242 7e-220 769.6 Lactobacillaceae ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0409 Bacteria 1TQ22@1239,3F48Z@33958,4HA7K@91061,COG0282@1,COG0282@2 NA|NA|NA F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction PGHMIELC_01439 220668.lp_2243 3.6e-186 657.5 Lactobacillaceae ytxK 2.1.1.72 ko:K00571 ko00000,ko01000,ko02048 Bacteria 1TRIQ@1239,3F4CI@33958,4H9SE@91061,COG0827@1,COG0827@2 NA|NA|NA L N-6 DNA Methylase PGHMIELC_01441 220668.lp_2244 4.5e-88 330.5 Lactobacillaceae Bacteria 1U61F@1239,2DKN6@1,30A0S@2,3F6TY@33958,4IFQB@91061 NA|NA|NA S Prokaryotic N-terminal methylation motif PGHMIELC_01442 60520.HR47_12770 8.6e-20 102.4 Lactobacillaceae ko:K02671 ko00000,ko02035,ko02044 Bacteria 1U8KD@1239,2A0ZU@1,30P57@2,3FB2V@33958,4IIIC@91061 NA|NA|NA PGHMIELC_01443 220668.lp_2246 3.2e-83 314.3 Lactobacillaceae gspG GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 ko:K02246,ko:K02456,ko:K10924 ko03070,ko05111,map03070,map05111 M00331,M00429 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1U5RV@1239,3F6E9@33958,4IFG1@91061,COG2165@1,COG2165@2 NA|NA|NA NU general secretion pathway protein PGHMIELC_01444 220668.lp_2247 5.5e-43 180.3 Lactobacillaceae comGC GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 ko:K02245,ko:K02456 ko03070,ko05111,map03070,map05111 M00331,M00429 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1VFI9@1239,3F7ZC@33958,4HNNT@91061,COG4537@1,COG4537@2 NA|NA|NA U competence protein ComGC PGHMIELC_01445 220668.lp_2248 1.9e-189 668.3 Lactobacillaceae comGB ko:K02244 M00429 ko00000,ko00002,ko02044 3.A.14.1 Bacteria 1U00C@1239,3F3S9@33958,4HGUA@91061,COG1459@1,COG1459@2 NA|NA|NA NU type II secretion system PGHMIELC_01446 220668.lp_2249 1.6e-174 618.6 Lactobacillaceae comGA ko:K02243 M00429 ko00000,ko00002,ko02044 3.A.14.1 Bacteria 1TPGE@1239,3F4HY@33958,4HB0C@91061,COG2804@1,COG2804@2 NA|NA|NA NU Type II IV secretion system protein PGHMIELC_01447 220668.lp_2251 4.8e-160 570.5 Lactobacillaceae rbsK 2.7.1.15 ko:K00852 ko00030,map00030 R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TQRC@1239,3F3S5@33958,4HA87@91061,COG0524@1,COG0524@2 NA|NA|NA H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway PGHMIELC_01448 220668.lp_2253 8.3e-131 473.0 Lactobacillaceae yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 Bacteria 1TPP5@1239,3F4WF@33958,4H9WJ@91061,COG0217@1,COG0217@2 NA|NA|NA K Transcriptional regulatory protein PGHMIELC_01449 220668.lp_2254 1.6e-49 201.8 Lactobacillaceae ko:K09004 ko00000 Bacteria 1VEYT@1239,3F7R7@33958,4HP12@91061,COG1416@1,COG1416@2 NA|NA|NA S DsrE/DsrF-like family PGHMIELC_01450 220668.lp_2255 2.3e-164 584.7 Lactobacillaceae 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 GH20 Bacteria 1VSC9@1239,3F4RS@33958,4HUQI@91061,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase domain protein TIM barrel PGHMIELC_01451 220668.lp_2256 1.9e-181 641.7 Lactobacillaceae ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02529 ko00000,ko03000 Bacteria 1TQ7K@1239,3F4AA@33958,4H9NG@91061,COG1609@1,COG1609@2 NA|NA|NA K catabolite control protein A PGHMIELC_01452 220668.lp_2258 1.7e-215 755.0 Lactobacillaceae pepQ 3.4.13.9 ko:K01271 ko00000,ko01000,ko01002 Bacteria 1TQ6R@1239,3F3X5@33958,4HA5I@91061,COG0006@1,COG0006@2 NA|NA|NA E Creatinase/Prolidase N-terminal domain PGHMIELC_01453 220668.lp_2259 1.1e-80 305.8 Lactobacillaceae Bacteria 1V3QI@1239,3F5A9@33958,4HH53@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance PGHMIELC_01454 220668.lp_2260 2.8e-56 224.9 Lactobacillaceae Bacteria 1U70A@1239,2DKTG@1,30AR7@2,3F8T5@33958,4IGUM@91061 NA|NA|NA PGHMIELC_01455 220668.lp_2261 1.9e-23 115.5 Lactobacillaceae WQ51_05790 Bacteria 1VAXN@1239,3F6KB@33958,4HM93@91061,COG4768@1,COG4768@2 NA|NA|NA S protein containing a divergent version of the methyl-accepting chemotaxis-like domain PGHMIELC_01456 220668.lp_2262 2.6e-158 564.7 Lactobacillaceae ykuT GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0042802,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 ko:K22044 ko00000,ko02000 1.A.23.3 Bacteria 1TR9Z@1239,3F49U@33958,4HCB8@91061,COG0668@1,COG0668@2 NA|NA|NA M mechanosensitive ion channel PGHMIELC_01457 220668.lp_2263 3.2e-225 787.3 Lactobacillaceae hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823,ko:K21613 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPD7@1239,3F419@33958,4H9SG@91061,COG1473@1,COG1473@2 NA|NA|NA E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate PGHMIELC_01458 220668.lp_2264 2.6e-76 292.0 Lactobacillaceae dapD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 iSbBS512_1146.SbBS512_E0158,iYO844.BSU14180 Bacteria 1TQUJ@1239,3F3U0@33958,4H9KY@91061,COG2171@1,COG2171@2 NA|NA|NA E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate PGHMIELC_01459 220668.lp_2265 6.5e-87 326.6 Lactobacillaceae ykuL Bacteria 1V9HN@1239,3F678@33958,4HH3X@91061,COG0517@1,COG0517@2 NA|NA|NA S (CBS) domain PGHMIELC_01460 220668.lp_2266 1.2e-94 352.4 Lactobacillaceae ko:K07095 ko00000 Bacteria 1VA0U@1239,3F73R@33958,4HM24@91061,COG0622@1,COG0622@2 NA|NA|NA S Phosphoesterase PGHMIELC_01461 220668.lp_2267 1e-110 406.0 Lactobacillaceae rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 1V6RN@1239,3F3KD@33958,4HCP6@91061,COG0127@1,COG0127@2 NA|NA|NA F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions PGHMIELC_01462 220668.lp_2268 9e-150 536.2 Lactobacillaceae murI GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0042802,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 R00260 RC00302 ko00000,ko00001,ko01000,ko01011 iYO844.BSU28390 Bacteria 1TPPR@1239,3F446@33958,4HA46@91061,COG0796@1,COG0796@2 NA|NA|NA M Provides the (R)-glutamate required for cell wall biosynthesis PGHMIELC_01463 220668.lp_2269 7.6e-126 456.4 Lactobacillaceae yslB Bacteria 1VD7N@1239,3F7ZI@33958,4HKV3@91061,COG1719@1,COG1719@2 NA|NA|NA S Protein of unknown function (DUF2507) PGHMIELC_01464 220668.lp_2270 3.3e-52 210.7 Lactobacillaceae trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1VA3Y@1239,3F6Y3@33958,4HKKX@91061,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family PGHMIELC_01465 220668.lp_2271 0.0 1495.7 Lactobacillaceae mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TP5W@1239,3F4DX@33958,4H9NZ@91061,COG1193@1,COG1193@2 NA|NA|NA L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity PGHMIELC_01466 220668.lp_2272 2.7e-36 157.5 Lactobacillaceae zapA GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047 ko:K09888 ko00000,ko03036 Bacteria 1VFZS@1239,3F7ZA@33958,4HP4T@91061,COG3027@1,COG3027@2 NA|NA|NA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division PGHMIELC_01467 220668.lp_2273 1.6e-48 198.4 Lactobacillaceae yrzB Bacteria 1VAPW@1239,3F6X3@33958,4HKV7@91061,COG3906@1,COG3906@2 NA|NA|NA S Belongs to the UPF0473 family PGHMIELC_01468 220668.lp_2274 7.3e-74 283.1 Lactobacillaceae yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07447 ko00000,ko01000 Bacteria 1V6ER@1239,3F6NI@33958,4HH04@91061,COG0816@1,COG0816@2 NA|NA|NA J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA PGHMIELC_01469 220668.lp_2275 2.4e-43 181.0 Lactobacillaceae yrzL Bacteria 1VAC4@1239,3F7EG@33958,4HKD0@91061,COG4472@1,COG4472@2 NA|NA|NA S Belongs to the UPF0297 family PGHMIELC_01470 220668.lp_2277 0.0 1743.0 Lactobacillaceae alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPK6@1239,3F3QS@33958,4H9XC@91061,COG0013@1,COG0013@2 NA|NA|NA J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain PGHMIELC_01471 220668.lp_2278 9.3e-245 852.4 Lactobacillaceae cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TPAP@1239,3F4FQ@33958,4HA98@91061,COG0513@1,COG0513@2 NA|NA|NA JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures PGHMIELC_01472 220668.lp_2279 7e-178 629.8 Lactobacillaceae nrnA GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPXX@1239,3F4FC@33958,4H9ZW@91061,COG0618@1,COG0618@2 NA|NA|NA S DHHA1 domain protein PGHMIELC_01473 220668.lp_2280 5.3e-217 760.0 Lactobacillaceae dinB GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031668,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 ko:K02346 ko00000,ko01000,ko03400 Bacteria 1TP42@1239,3F44N@33958,4HADJ@91061,COG0389@1,COG0389@2 NA|NA|NA L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII PGHMIELC_01474 220668.lp_2281 2.8e-29 134.8 Lactobacillaceae yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VEMC@1239,3F7EY@33958,4HNK0@91061,COG1862@1,COG1862@2 NA|NA|NA U Preprotein translocase PGHMIELC_01475 220668.lp_2282 3.3e-227 793.9 Lactobacillaceae tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 R03789,R10209 RC00063 ko00000,ko01000,ko03016 Bacteria 1TNZ4@1239,3F43F@33958,4HCNM@91061,COG0343@1,COG0343@2 NA|NA|NA F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) PGHMIELC_01476 220668.lp_2285 6.3e-201 706.4 Lactobacillaceae queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 ko00000,ko01000,ko03016 Bacteria 1TPKD@1239,3F3VG@33958,4H9PT@91061,COG0809@1,COG0809@2 NA|NA|NA J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) PGHMIELC_01477 220668.lp_2286 2.1e-188 664.8 Lactobacillaceae ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TR47@1239,3F47S@33958,4HBMW@91061,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing PGHMIELC_01478 220668.lp_2287 4.6e-106 390.6 Lactobacillaceae ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1V3KF@1239,3F42W@33958,4HHI5@91061,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB PGHMIELC_01479 220668.lp_2289 2.7e-91 341.3 Lactobacillaceae Bacteria 1U5PA@1239,29NVQ@1,309TT@2,3F69E@33958,4IFDT@91061 NA|NA|NA PGHMIELC_01480 220668.lp_2290 0.0 1919.1 Lactobacillaceae Bacteria 1TPVY@1239,3F4AK@33958,4HD9X@91061,COG4485@1,COG4485@2 NA|NA|NA S Bacterial membrane protein YfhO PGHMIELC_01481 220668.lp_2292 1.3e-72 278.9 Lactobacillaceae Bacteria 1U674@1239,29P6P@1,30A4T@2,3F78E@33958,4IFXQ@91061 NA|NA|NA PGHMIELC_01482 220668.lp_2297 0.0 1247.6 Lactobacillaceae mutL GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TPGK@1239,3F3PK@33958,4HB34@91061,COG0323@1,COG0323@2 NA|NA|NA L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex PGHMIELC_01483 220668.lp_2298 0.0 1620.5 Lactobacillaceae mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TPRJ@1239,3F4A5@33958,4HA63@91061,COG0249@1,COG0249@2 NA|NA|NA L that it carries out the mismatch recognition step. This protein has a weak ATPase activity PGHMIELC_01484 220668.lp_2299 2.7e-154 551.2 Lactobacillaceae ymdB GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 ko:K02029,ko:K02030,ko:K09769 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TR9P@1239,3F484@33958,4HAV5@91061,COG1692@1,COG1692@2 NA|NA|NA S YmdB-like protein PGHMIELC_01485 220668.lp_2300 2.1e-216 758.4 Lactobacillaceae rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TP48@1239,3F3WX@33958,4HC9J@91061,COG1418@1,COG1418@2 NA|NA|NA S Endoribonuclease that initiates mRNA decay PGHMIELC_01486 220668.lp_2301 5e-191 673.7 Lactobacillaceae recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 ko:K03553 ko03440,map03440 M00729 ko00000,ko00001,ko00002,ko03400 Bacteria 1TPD5@1239,3F3KU@33958,4HAG5@91061,COG0468@1,COG0468@2 NA|NA|NA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage PGHMIELC_01487 220668.lp_2302 9.4e-231 805.8 Lactobacillaceae cinA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 1TQ1N@1239,3F4I4@33958,4HATN@91061,COG1058@1,COG1058@2,COG1546@1,COG1546@2 NA|NA|NA S Belongs to the CinA family PGHMIELC_01488 220668.lp_2303 3.7e-97 360.9 Lactobacillaceae pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 iSB619.SA_RS06365 Bacteria 1V6PJ@1239,3F4BI@33958,4HCEX@91061,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family PGHMIELC_01489 220668.lp_2304 5.7e-110 404.1 Lactobacillaceae ymfM ko:K15539 ko00000 Bacteria 1V1N7@1239,3F3SM@33958,4HKW3@91061,COG1426@1,COG1426@2 NA|NA|NA S Helix-turn-helix domain PGHMIELC_01490 220668.lp_2305 2.9e-251 874.0 Lactobacillaceae ymfH ko:K07263 ko00000,ko01000,ko01002 Bacteria 1TP5I@1239,3F4MU@33958,4H9YG@91061,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 PGHMIELC_01491 220668.lp_2306 6.5e-232 809.7 Lactobacillaceae ymfF Bacteria 1TPN6@1239,3F3SA@33958,4H9P5@91061,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 inactive domain protein PGHMIELC_01492 220668.lp_2308 1e-254 885.6 Lactobacillaceae lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iYO844.BSU03790 Bacteria 1TPQJ@1239,3F48V@33958,4HAEP@91061,COG0527@1,COG0527@2 NA|NA|NA E Belongs to the aspartokinase family PGHMIELC_01493 220668.lp_2312 1.5e-155 555.4 Lactobacillaceae aatB ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TQNR@1239,3F3WC@33958,4HF14@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter substrate-binding protein PGHMIELC_01494 220668.lp_2313 2.5e-115 421.4 Lactobacillaceae glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1UYAZ@1239,3FC39@33958,4HFTM@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein PGHMIELC_01495 220668.lp_2314 4.6e-109 400.6 Lactobacillaceae glnP ko:K02029,ko:K02030,ko:K17073,ko:K17074 ko02010,map02010 M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1V280@1239,3F3VF@33958,4HGMH@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease PGHMIELC_01496 220668.lp_2315 1.2e-146 525.8 Lactobacillaceae minD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03609 ko00000,ko03036,ko04812 Bacteria 1TP6P@1239,3F3U8@33958,4HB2F@91061,COG2894@1,COG2894@2 NA|NA|NA D Belongs to the ParA family PGHMIELC_01497 220668.lp_2316 1.4e-116 425.6 Lactobacillaceae minC GO:0000910,GO:0007049,GO:0008150,GO:0009987,GO:0022402,GO:0032506,GO:0036214,GO:0051179,GO:0051301,GO:0061640 ko:K03610 ko00000,ko03036,ko04812 Bacteria 1VAPC@1239,3F61V@33958,4HBTI@91061,COG0850@1,COG0850@2 NA|NA|NA D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization PGHMIELC_01498 220668.lp_2317 1.2e-88 332.4 Lactobacillaceae mreD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 ko:K03571 ko00000,ko03036 9.B.157.1 Bacteria 1VEV7@1239,3F6PG@33958,4HPAC@91061,COG2891@1,COG2891@2 NA|NA|NA M rod shape-determining protein MreD PGHMIELC_01499 220668.lp_2318 2.6e-144 518.1 Lactobacillaceae mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 ko:K03570 ko00000,ko03036 9.B.157.1 Bacteria 1TR1V@1239,3F3MC@33958,4HB0K@91061,COG1792@1,COG1792@2 NA|NA|NA M Involved in formation and maintenance of cell shape PGHMIELC_01500 220668.lp_2319 2.8e-161 574.7 Lactobacillaceae mreB ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 1TP51@1239,3F3ZV@33958,4HA4S@91061,COG1077@1,COG1077@2 NA|NA|NA D cell shape determining protein MreB PGHMIELC_01501 220668.lp_2320 1.3e-116 425.6 Lactobacillaceae radC ko:K03630 ko00000 Bacteria 1TQ3K@1239,3F5IM@33958,4HB1W@91061,COG2003@1,COG2003@2 NA|NA|NA L DNA repair protein PGHMIELC_01502 220668.lp_2321 4.7e-249 866.7 Lactobacillaceae folC 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0166 Bacteria 1TPX5@1239,3F498@33958,4HBJM@91061,COG0285@1,COG0285@2 NA|NA|NA H Belongs to the folylpolyglutamate synthase family PGHMIELC_01503 1136177.KCA1_1966 0.0 1666.4 Lactobacillaceae valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iLJ478.TM1817 Bacteria 1TPN4@1239,3F3RB@33958,4HB85@91061,COG0525@1,COG0525@2 NA|NA|NA J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner PGHMIELC_01504 220668.lp_2323 3e-89 334.7 Lactobacillaceae tpx 1.11.1.15 ko:K11065 ko00000,ko01000 Bacteria 1V474@1239,3F5VY@33958,4HFMW@91061,COG2077@1,COG2077@2 NA|NA|NA O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides PGHMIELC_01505 220668.lp_2324 2.9e-232 810.8 Lactobacillaceae gshF 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPGX@1239,3F506@33958,4HAMJ@91061,COG2918@1,COG2918@2 NA|NA|NA H Belongs to the glutamate--cysteine ligase type 1 family PGHMIELC_01506 220668.lp_2325 1.9e-228 798.1 Lactobacillaceae thiI GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07461 ko00000,ko00001,ko01000,ko03016 iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307 Bacteria 1TPNW@1239,3F3N0@33958,4HAV9@91061,COG0301@1,COG0301@2 NA|NA|NA H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS PGHMIELC_01507 220668.lp_2326 1.7e-218 765.0 Lactobacillaceae iscS2 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TP21@1239,3F4CD@33958,4HAEE@91061,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class V PGHMIELC_01508 220668.lp_2328 0.0 1078.9 Lactobacillaceae ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 ko:K06286,ko:K07158 ko00000,ko03036 Bacteria 1TQR7@1239,3F47K@33958,4HA15@91061,COG4477@1,COG4477@2 NA|NA|NA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization PGHMIELC_01509 220668.lp_2330 5e-81 307.0 Lactobacillaceae ytsP 1.8.4.14 ko:K08968 ko00270,map00270 R02025 RC00639 ko00000,ko00001,ko01000 Bacteria 1V6GQ@1239,3F6NT@33958,4HH7X@91061,COG1956@1,COG1956@2 NA|NA|NA T GAF domain-containing protein PGHMIELC_01510 220668.lp_2331 3.1e-107 394.4 Lactobacillaceae rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 ko:K02986 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TR0J@1239,3F3P0@33958,4HAC9@91061,COG0522@1,COG0522@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit PGHMIELC_01511 220668.lp_2332 2.6e-112 411.4 Lactobacillaceae yktB Bacteria 1UY83@1239,3F62K@33958,4HEDB@91061,COG4493@1,COG4493@2 NA|NA|NA S Belongs to the UPF0637 family PGHMIELC_01512 220668.lp_2333 3.3e-80 304.3 Lactobacillaceae yueI Bacteria 1VFCV@1239,3F64D@33958,4HNNE@91061,COG5506@1,COG5506@2 NA|NA|NA S Protein of unknown function (DUF1694) PGHMIELC_01513 220668.lp_2334 3.1e-110 404.4 Lactobacillaceae Bacteria 1VBIT@1239,3F4IE@33958,4HK10@91061,COG5658@1,COG5658@2 NA|NA|NA S Protein of unknown function (DUF1648) PGHMIELC_01514 220668.lp_2335 8.6e-44 182.6 Lactobacillaceae czrA Bacteria 1VA3M@1239,3F7BF@33958,4I4FT@91061,COG0640@1,COG0640@2 NA|NA|NA K Helix-turn-helix domain PGHMIELC_01515 1123284.KB899046_gene2248 5.1e-232 810.4 Bacilli malL 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13 Bacteria 1TP53@1239,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G COG0366 Glycosidases PGHMIELC_01516 1423732.BALS01000065_gene2247 9.2e-42 176.4 Lactobacillaceae 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1V7TP@1239,3F76S@33958,4IQPD@91061,COG2893@1,COG2893@2 NA|NA|NA G PTS system fructose IIA component PGHMIELC_01517 411460.RUMTOR_00564 2.7e-104 385.2 Clostridia ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1TSXA@1239,25C3C@186801,COG3716@1,COG3716@2 NA|NA|NA G PTS system mannose fructose sorbose family IID component PGHMIELC_01518 1423734.JCM14202_2897 3.6e-103 381.3 Lactobacillaceae ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1TSX0@1239,3F4X4@33958,4HBRB@91061,COG3715@1,COG3715@2 NA|NA|NA G PTS system sorbose-specific iic component PGHMIELC_01519 1423734.JCM14202_2898 6e-66 256.9 Lactobacillaceae 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1V8BP@1239,3F6R3@33958,4HWNX@91061,COG3444@1,COG3444@2 NA|NA|NA G PTS system sorbose subfamily IIB component PGHMIELC_01520 1423734.JCM14202_2899 5.9e-95 354.4 Lactobacillaceae cytR 5.1.1.1 ko:K01775,ko:K05499 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011,ko03000 Bacteria 1TRHK@1239,3F5FI@33958,4HB9P@91061,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding proteins and sugar binding domain of LacI family PGHMIELC_01521 220668.lp_2336 0.0 1452.2 Lactobacillaceae gshF 6.3.2.2 ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 M00118,M00582 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPGX@1239,3F506@33958,4HAMJ@91061,COG0189@1,COG0189@2,COG2918@1,COG2918@2 NA|NA|NA H Belongs to the glutamate--cysteine ligase type 1 family PGHMIELC_01522 220668.lp_2337 1.8e-237 828.2 Lactobacillaceae rarA ko:K07478 ko00000 Bacteria 1TPVV@1239,3F3WF@33958,4HAIS@91061,COG2256@1,COG2256@2 NA|NA|NA L recombination factor protein RarA PGHMIELC_01523 220668.lp_2339 1.5e-38 165.2 Lactobacillaceae Bacteria 1U68P@1239,2A52V@1,30TRA@2,3F7BD@33958,4IFZS@91061 NA|NA|NA PGHMIELC_01524 1136177.KCA1_1981 6.2e-82 310.1 Lactobacillaceae usp6 ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1V3NY@1239,3F68T@33958,4HIP3@91061,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein PGHMIELC_01525 220668.lp_2341 1e-199 702.6 Lactobacillaceae bla2 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1UYZ3@1239,3F5IH@33958,4HFV8@91061,COG2367@1,COG2367@2 NA|NA|NA V Beta-lactamase enzyme family PGHMIELC_01526 220668.lp_2342 3.3e-161 574.3 Lactobacillaceae 2.3.1.19 ko:K00634,ko:K07729 ko00650,ko01100,map00650,map01100 R01174 RC00004,RC02816 ko00000,ko00001,ko01000,ko03000 Bacteria 1VMYH@1239,3F5QH@33958,4ISF0@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins PGHMIELC_01527 220668.lp_2344 5.1e-295 1019.6 Lactobacillaceae glpQ3 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1UG1C@1239,3F5UQ@33958,4HCPQ@91061,COG0584@1,COG0584@2 NA|NA|NA C Glycerophosphoryl diester phosphodiesterase family PGHMIELC_01528 220668.lp_2345 5.4e-214 750.0 Lactobacillaceae ddl 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TP2Y@1239,3F41Z@33958,4H9KB@91061,COG1181@1,COG1181@2 NA|NA|NA F Belongs to the D-alanine--D-alanine ligase family PGHMIELC_01529 220668.lp_2346 3.6e-188 664.1 Lactobacillaceae qor 1.1.1.1,1.6.5.5 ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1TRNC@1239,3F48F@33958,4HATC@91061,COG0604@1,COG0604@2 NA|NA|NA C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily PGHMIELC_01530 220668.lp_2347 3.5e-177 627.5 Lactobacillaceae Bacteria 1V3Z9@1239,29SNM@1,30DU7@2,3F3VM@33958,4HHKX@91061 NA|NA|NA S Protein of unknown function (DUF2785) PGHMIELC_01531 220668.lp_2349 2.8e-168 597.8 Lactobacillaceae hicD1 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1UXY2@1239,3F4M2@33958,4HD1S@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily PGHMIELC_01532 220668.lp_2350 6.5e-148 530.0 Lactobacillaceae metQ ko:K02072,ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TQAS@1239,3FC6J@33958,4HBK0@91061,COG1464@1,COG1464@2 NA|NA|NA M Belongs to the nlpA lipoprotein family PGHMIELC_01533 60520.HR47_13195 1.4e-111 409.1 Lactobacillaceae metI GO:0000101,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015821,GO:0015849,GO:0016020,GO:0042940,GO:0044464,GO:0046942,GO:0048473,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072348 ko:K02069,ko:K02072 ko02010,map02010 M00211,M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24,9.B.25.1 Bacteria 1TR59@1239,3FC5J@33958,4H9NA@91061,COG2011@1,COG2011@2 NA|NA|NA U ABC transporter permease PGHMIELC_01534 220668.lp_2352 4e-187 660.6 Lactobacillaceae metN GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 ko:K02071 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 iYO844.BSU32750 Bacteria 1TPPN@1239,3F3U5@33958,4H9VX@91061,COG1135@1,COG1135@2 NA|NA|NA P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system PGHMIELC_01535 220668.lp_2353 3.6e-48 197.2 Lactobacillaceae gcsH2 ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 Bacteria 1V6WV@1239,3F7WB@33958,4HIMA@91061,COG0509@1,COG0509@2 NA|NA|NA E glycine cleavage PGHMIELC_01536 220668.lp_2354 9.3e-220 769.2 Lactobacillaceae rodA ko:K05837 ko00000,ko03036 Bacteria 1TPGH@1239,3F4J4@33958,4HAV4@91061,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family PGHMIELC_01537 220668.lp_2357 3.3e-33 147.1 Lactobacillaceae Bacteria 1U6GB@1239,2BQ47@1,302KN@2,3F7UY@33958,4IG8F@91061 NA|NA|NA S Protein of unknown function (DUF2969) PGHMIELC_01538 220668.lp_2358 2.3e-43 181.0 Lactobacillaceae yidD ko:K08998 ko00000 Bacteria 1VEIG@1239,3F7H1@33958,4HPA3@91061,COG0759@1,COG0759@2 NA|NA|NA S Could be involved in insertion of integral membrane proteins into the membrane PGHMIELC_01539 220668.lp_2359 2.7e-180 637.9 Lactobacillaceae mbl ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 1TP51@1239,3F463@33958,4HA4S@91061,COG1077@1,COG1077@2 NA|NA|NA D Cell shape determining protein MreB Mrl PGHMIELC_01540 220668.lp_2360 2.1e-102 378.3 Lactobacillaceae ko:K03817 ko00000,ko01000,ko03009 Bacteria 1V3NE@1239,3FB7G@33958,4HG1N@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain PGHMIELC_01541 220668.lp_2361 4.4e-247 860.1 Lactobacillaceae murA 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 Bacteria 1TPAU@1239,3F3P8@33958,4H9KI@91061,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine PGHMIELC_01542 1136177.KCA1_1998 1.1e-50 206.1 Lactobacillaceae atpC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190 Bacteria 1VA89@1239,3F6I6@33958,4HKHS@91061,COG0355@1,COG0355@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane PGHMIELC_01543 220668.lp_2364 2.1e-263 914.4 Lactobacillaceae atpD 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iSB619.SA_RS10965 Bacteria 1TPGF@1239,3F3TF@33958,4HAT6@91061,COG0055@1,COG0055@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits PGHMIELC_01544 220668.lp_2365 2.3e-165 588.2 Lactobacillaceae atpG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611,iSB619.SA_RS10970,iYO844.BSU36820 Bacteria 1TPBX@1239,3F40E@33958,4HB0E@91061,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex PGHMIELC_01545 220668.lp_2366 2.7e-280 970.7 Lactobacillaceae atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 Bacteria 1TNZ8@1239,3F3R4@33958,4HAMZ@91061,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit PGHMIELC_01546 220668.lp_2367 1.8e-90 338.6 Lactobacillaceae atpH GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 1VAG3@1239,3FC7Z@33958,4HKW1@91061,COG0712@1,COG0712@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation PGHMIELC_01547 1136177.KCA1_2003 6e-51 207.2 Lactobacillaceae atpF ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iHN637.CLJU_RS01170,iYO844.BSU36850 Bacteria 1VB85@1239,3F5M8@33958,4HM64@91061,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) PGHMIELC_01548 1136177.KCA1_2004 2.5e-27 127.5 Lactobacillaceae atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 1VEHP@1239,3F82A@33958,4HNKQ@91061,COG0636@1,COG0636@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation PGHMIELC_01549 220668.lp_2370 6.5e-128 463.4 Lactobacillaceae atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666 Bacteria 1TQIT@1239,3F3RE@33958,4H9NV@91061,COG0356@1,COG0356@2 NA|NA|NA C it plays a direct role in the translocation of protons across the membrane PGHMIELC_01550 220668.lp_2371 1e-232 812.4 Lactobacillaceae pyrP ko:K02824,ko:K16169 ko00000,ko02000 2.A.40.1.1,2.A.40.1.2,2.A.40.3.1 iLJ478.TM0819 Bacteria 1TQKX@1239,3F3UJ@33958,4HAEU@91061,COG2233@1,COG2233@2 NA|NA|NA F Permease PGHMIELC_01551 1136177.KCA1_2007 4.7e-114 417.2 Lactobacillaceae upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000 iSB619.SA_RS11010 Bacteria 1TPMT@1239,3F4M0@33958,4H9Y0@91061,COG0035@1,COG0035@2 NA|NA|NA F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate PGHMIELC_01552 220668.lp_2375 1.1e-231 808.9 Lactobacillaceae glyA 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQVM@1239,3F4C1@33958,4HA5K@91061,COG0112@1,COG0112@2 NA|NA|NA E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism PGHMIELC_01553 220668.lp_2376 6.9e-192 676.4 Lactobacillaceae ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87,3.1.3.48 ko:K01104,ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 1TP1I@1239,3F3T1@33958,4HA7W@91061,COG0009@1,COG0009@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine PGHMIELC_01554 220668.lp_2377 1e-159 569.3 Lactobacillaceae prmB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564 2.1.1.297,2.1.1.298 ko:K02493,ko:K07320 R10806 RC00003,RC03279 ko00000,ko01000,ko03009,ko03012 Bacteria 1TSMA@1239,3F460@33958,4HC6W@91061,COG2890@1,COG2890@2 NA|NA|NA J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif PGHMIELC_01555 220668.lp_2378 1.2e-197 695.7 Lactobacillaceae prfA ko:K02835 ko00000,ko03012 Bacteria 1TQ7V@1239,3F3Q0@33958,4H9MB@91061,COG0216@1,COG0216@2 NA|NA|NA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA PGHMIELC_01556 220668.lp_2379 9.3e-109 399.4 Lactobacillaceae tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 iAF1260.b1238,iBWG_1329.BWG_1065,iECDH10B_1368.ECDH10B_1298,iECDH1ME8569_1439.ECDH1ME8569_1176,iEcDH1_1363.EcDH1_2411,iJO1366.b1238,iJR904.b1238,iPC815.YPO2176,iY75_1357.Y75_RS06470 Bacteria 1TRVM@1239,3F4UE@33958,4HA4A@91061,COG1435@1,COG1435@2 NA|NA|NA F thymidine kinase PGHMIELC_01557 220668.lp_2380 1.5e-263 914.8 Lactobacillaceae murF 6.3.2.10,6.3.2.13 ko:K01928,ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R02788,R04573,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TRG9@1239,3FBS5@33958,4HAMY@91061,COG0770@1,COG0770@2 NA|NA|NA M Domain of unknown function (DUF1727) PGHMIELC_01558 220668.lp_2382 5.9e-137 493.4 Lactobacillaceae cobQ ko:K07009 ko00000 Bacteria 1U7I9@1239,3F4CH@33958,4HD1P@91061,COG3442@1,COG3442@2 NA|NA|NA S glutamine amidotransferase PGHMIELC_01559 220668.lp_2384 9.8e-196 689.1 Lactobacillaceae manA 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 1VRGI@1239,3F40I@33958,4HBFW@91061,COG1482@1,COG1482@2 NA|NA|NA G mannose-6-phosphate isomerase PGHMIELC_01560 220668.lp_2385 1.4e-192 678.7 Lactobacillaceae ampC Bacteria 1TNZX@1239,3F3WZ@33958,4IPJT@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase PGHMIELC_01561 220668.lp_2388 5.2e-29 132.9 Lactobacillaceae Bacteria 1U798@1239,29PZR@1,30AY6@2,3F958@33958,4IH44@91061 NA|NA|NA PGHMIELC_01562 220668.lp_2390 1e-203 715.7 Lactobacillaceae ilvE 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TQQI@1239,3F4BD@33958,4HASX@91061,COG0115@1,COG0115@2 NA|NA|NA E Branched-chain amino acid aminotransferase PGHMIELC_01563 220668.lp_2391 1.9e-58 231.5 Lactobacillaceae Bacteria 1W08C@1239,2FI40@1,349WT@2,3F7QX@33958,4HYGC@91061 NA|NA|NA PGHMIELC_01564 220668.lp_2393 5.3e-125 454.1 Lactobacillaceae Bacteria 1VWGD@1239,2F31P@1,33VWT@2,3F4CP@33958,4HWD9@91061 NA|NA|NA PGHMIELC_01565 220668.lp_2394 0.0 1213.4 Lactobacillaceae yfiC ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter PGHMIELC_01566 220668.lp_2395 0.0 1076.6 Lactobacillaceae ycfI GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K06147,ko:K18891 ko02010,map02010 M00708 ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 Bacteria 1TP0B@1239,3F3SP@33958,4H9SC@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter, ATP-binding protein PGHMIELC_01567 220668.lp_2396 3.3e-65 254.2 Lactobacillaceae Bacteria 1VHCQ@1239,3F7UC@33958,4HNS8@91061,COG5294@1,COG5294@2 NA|NA|NA S Protein of unknown function (DUF1093) PGHMIELC_01568 220668.lp_2397 3.8e-135 487.6 Lactobacillaceae yxkH Bacteria 1V6AW@1239,3F5UZ@33958,4HHC9@91061,COG0726@1,COG0726@2 NA|NA|NA G Polysaccharide deacetylase PGHMIELC_01571 1591072.A0A0B5CYL8_9CAUD 1.4e-79 303.1 Siphoviridae Viruses 4QDM1@10239,4QN41@10699,4QUD4@28883 NA|NA|NA PGHMIELC_01572 220668.lp_2399 8.5e-34 149.8 Lactobacillaceae hol Bacteria 1W4HU@1239,3F6KT@33958,4I17D@91061,COG5546@1,COG5546@2 NA|NA|NA S Bacteriophage holin PGHMIELC_01573 220668.lp_0682 4.4e-46 190.3 Lactobacillaceae Bacteria 1U7NR@1239,2BK1I@1,32EER@2,3F9YI@33958,4IHK1@91061 NA|NA|NA PGHMIELC_01574 220668.lp_0681 2.7e-184 651.4 Lactobacillaceae ko:K07273 ko00000 Bacteria 1V3SH@1239,3F6ZF@33958,4HNR1@91061,COG3757@1,COG3757@2 NA|NA|NA M hydrolase, family 25 PGHMIELC_01576 60520.HR47_13405 1.6e-71 275.4 Lactobacillaceae Bacteria 1U89U@1239,29QKT@1,30BKF@2,3FAR1@33958,4II7S@91061 NA|NA|NA S Protein of unknown function (DUF1617) PGHMIELC_01577 60520.HR47_13410 0.0 1730.7 Lactobacillaceae sidC ko:K15482,ko:K20444 ko05134,map05134 ko00000,ko00001,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria 1VF6N@1239,3F4PQ@33958,4HQY1@91061,COG0497@1,COG0497@2,COG0845@1,COG0845@2 NA|NA|NA LM DNA recombination PGHMIELC_01578 60520.HR47_13415 5.9e-61 240.0 Lactobacillaceae Bacteria 1VIA9@1239,2E4V0@1,32ZPD@2,3F7PW@33958,4HQ52@91061 NA|NA|NA PGHMIELC_01579 60520.HR47_13420 0.0 2590.8 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1UYS4@1239,3FBSQ@33958,4HEDZ@91061,COG1511@1,COG1511@2,COG3953@1,COG3953@2,COG5412@1,COG5412@2 NA|NA|NA D NLP P60 protein PGHMIELC_01580 60520.HR47_13425 8e-23 112.5 Lactobacillaceae Bacteria 1U6J1@1239,2DKQY@1,30AE9@2,3F80M@33958,4IGBJ@91061 NA|NA|NA PGHMIELC_01581 60520.HR47_13430 6.3e-64 250.0 Lactobacillaceae Bacteria 1VANE@1239,2DZQB@1,32VG5@2,3F7Z2@33958,4IGAN@91061 NA|NA|NA PGHMIELC_01582 60520.HR47_13435 1e-76 292.7 Lactobacillaceae Bacteria 1TUG5@1239,2B0XY@1,303GE@2,3F7I1@33958,4IG2U@91061 NA|NA|NA S Phage tail tube protein, TTP PGHMIELC_01583 60520.HR47_13440 1.9e-54 218.4 Lactobacillaceae Bacteria 1U6RY@1239,2DKRW@1,30AJB@2,3F8DZ@33958,4IGJF@91061 NA|NA|NA PGHMIELC_01584 60520.HR47_13445 1.3e-88 332.4 Lactobacillaceae Bacteria 1VGVJ@1239,2EA6Q@1,334BG@2,3F6M1@33958,4HRCT@91061 NA|NA|NA PGHMIELC_01585 60520.HR47_13450 1.5e-50 205.3 Lactobacillaceae Bacteria 1VMEP@1239,2END8@1,33G0Q@2,3F8M7@33958,4HYH5@91061 NA|NA|NA PGHMIELC_01586 60520.HR47_13455 4.6e-52 210.3 Lactobacillaceae Bacteria 1VKGB@1239,2EJE3@1,33D53@2,3F8XQ@33958,4HYI7@91061 NA|NA|NA PGHMIELC_01588 60520.HR47_13465 2e-175 621.7 Lactobacillaceae Bacteria 1TSI8@1239,2DB75@1,2Z7JY@2,3F5Z9@33958,4IRVK@91061 NA|NA|NA S Phage major capsid protein E PGHMIELC_01589 60520.HR47_13470 2.6e-50 204.5 Lactobacillaceae Bacteria 1VK8N@1239,2EHA7@1,33B23@2,3F87M@33958,4HXXJ@91061 NA|NA|NA PGHMIELC_01590 257314.LJ_0312 2.7e-14 85.9 Lactobacillaceae Bacteria 1VCZV@1239,2E0GW@1,32W2S@2,3F8TT@33958,4IFYE@91061 NA|NA|NA S Domain of unknown function (DUF4355) PGHMIELC_01592 60520.HR47_13485 2.4e-30 137.9 Lactobacillaceae Bacteria 1U8DJ@1239,2BT9V@1,32NFB@2,3FAV6@33958,4IIBH@91061 NA|NA|NA PGHMIELC_01593 60520.HR47_13490 4.7e-302 1043.1 Lactobacillaceae Bacteria 1U6KJ@1239,3F4ED@33958,4HFY6@91061,COG2369@1,COG2369@2 NA|NA|NA S Phage Mu protein F like protein PGHMIELC_01594 60520.HR47_13495 3.8e-38 163.7 Bacteria ko:K07584 ko00000 Bacteria COG2868@1,COG2868@2 NA|NA|NA J Cysteine protease Prp PGHMIELC_01595 60520.HR47_13500 1.3e-266 925.2 Lactobacillaceae Bacteria 1TR67@1239,2DB9U@1,2Z7Z6@2,3F4VA@33958,4HAC8@91061 NA|NA|NA S Phage portal protein, SPP1 Gp6-like PGHMIELC_01596 60520.HR47_13505 3.7e-240 837.0 Lactobacillaceae ps334 Bacteria 1TT2C@1239,3F3NN@33958,4H9S2@91061,COG1783@1,COG1783@2 NA|NA|NA S Terminase-like family PGHMIELC_01597 60520.HR47_13510 6.4e-64 250.4 Lactobacillaceae ps333 ko:K07474 ko00000 Bacteria 1VAD9@1239,3F6ZJ@33958,4HXMG@91061,COG3728@1,COG3728@2 NA|NA|NA L Terminase small subunit PGHMIELC_01598 220668.lp_2425 9.9e-13 79.0 Lactobacillaceae Bacteria 1W4M5@1239,2911N@1,2ZNP8@2,3F95E@33958,4I18X@91061 NA|NA|NA PGHMIELC_01600 1291743.LOSG293_110420 2.1e-18 97.8 Bacteria Bacteria 2EGHB@1,33A9F@2 NA|NA|NA S KTSC domain PGHMIELC_01603 220668.lp_0656 1.7e-81 308.5 Lactobacillaceae arpU Bacteria 1W30Q@1239,2DPRG@1,3333C@2,3F7WR@33958,4I13H@91061 NA|NA|NA S Phage transcriptional regulator, ArpU family PGHMIELC_01605 220668.lp_2433 8.4e-66 256.1 Lactobacillaceae rusA GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008821,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.1.22.4 ko:K01160 ko00000,ko01000,ko03400 Bacteria 1VFJ9@1239,3F8MJ@33958,4HQ3J@91061,COG4570@1,COG4570@2 NA|NA|NA L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC PGHMIELC_01606 220668.lp_2434 6.2e-64 250.4 Lactobacillaceae Bacteria 1U7BT@1239,29Q1G@1,30B01@2,3F9AZ@33958,4IH73@91061 NA|NA|NA PGHMIELC_01607 220668.lp_0645 1.6e-94 352.1 Lactobacillaceae Bacteria 1VVJU@1239,2F42A@1,33WTY@2,3FA6K@33958,4IHRN@91061 NA|NA|NA PGHMIELC_01608 60520.HR47_13590 7e-49 199.5 Lactobacillaceae Bacteria 1U7PZ@1239,29Q8U@1,30B7X@2,3FA00@33958,4IHMA@91061 NA|NA|NA PGHMIELC_01609 220668.lp_0643 2.3e-51 208.0 Lactobacillaceae Bacteria 1V6IW@1239,3FAFI@33958,4HJ9G@91061,COG3935@1,COG3935@2 NA|NA|NA L Domain of unknown function (DUF4373) PGHMIELC_01610 1462526.BN990_03892 2.3e-36 159.1 Bacilli Bacteria 1UHW4@1239,4HRBD@91061,COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase PGHMIELC_01613 1136177.KCA1_1106 1.1e-35 155.6 Lactobacillaceae Bacteria 1W39V@1239,2C0XI@1,2ZJRZ@2,3F7TU@33958,4I12U@91061 NA|NA|NA S Haemolysin XhlA PGHMIELC_01614 1136177.KCA1_1105 1.2e-200 705.7 Lactobacillaceae lys GO:0008150,GO:0009405,GO:0044419,GO:0051704 ko:K02656,ko:K07273,ko:K14196 ko05150,map05150 ko00000,ko00001,ko02035,ko02044 Bacteria 1V16P@1239,3FC13@33958,4HF99@91061,COG1388@1,COG1388@2,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 PGHMIELC_01615 1423807.BACO01000096_gene2531 2.9e-23 114.0 Lactobacillaceae Bacteria 1U83B@1239,29QH7@1,30BGN@2,3FAH6@33958,4II0R@91061 NA|NA|NA PGHMIELC_01616 1136177.KCA1_1103 5e-63 248.4 Lactobacillaceae Bacteria 1UIXH@1239,2B254@1,31UNB@2,3F55T@33958,4I0AP@91061 NA|NA|NA PGHMIELC_01619 1136177.KCA1_1100 3.9e-75 289.7 Lactobacillaceae Bacteria 1UWD6@1239,2EQYH@1,33II5@2,3F8V8@33958,4IGW7@91061 NA|NA|NA S Calcineurin-like phosphoesterase PGHMIELC_01622 913848.AELK01000127_gene1743 1.8e-100 372.9 Lactobacillaceae Bacteria 1VA6F@1239,3FA6R@33958,4HM18@91061,COG4926@1,COG4926@2 NA|NA|NA S Prophage endopeptidase tail PGHMIELC_01623 862514.HMPREF0623_0297 6.4e-47 194.5 Lactobacillaceae Bacteria 1VGQF@1239,2E9AZ@1,333IU@2,3F6FD@33958,4HQBT@91061 NA|NA|NA S Phage tail protein PGHMIELC_01624 862514.HMPREF0623_0296 1.9e-153 551.2 Lactobacillaceae ko:K11060,ko:K21471 ko00000,ko01000,ko01002,ko01011,ko02042 Bacteria 1UZN8@1239,3F3T2@33958,4HGQG@91061,COG0741@1,COG0741@2,COG0791@1,COG0791@2,COG3064@1,COG3064@2,COG5283@1,COG5283@2,COG5412@1,COG5412@2 NA|NA|NA M Phage tail tape measure protein TP901 PGHMIELC_01625 986075.CathTA2_0704 8.1e-13 80.9 Bacilli Bacteria 1VCXU@1239,2E0P6@1,32W81@2,4HM42@91061 NA|NA|NA S Bacteriophage Gp15 protein PGHMIELC_01627 862514.HMPREF0623_0292 1.5e-35 156.4 Lactobacillaceae Bacteria 1VAG5@1239,3F8R0@33958,4HMMA@91061,COG5492@1,COG5492@2 NA|NA|NA N domain, Protein PGHMIELC_01628 1395513.P343_12635 3.3e-10 71.6 Bacilli Bacteria 1VM7V@1239,2DRGS@1,33BP3@2,4HRZ1@91061 NA|NA|NA S Minor capsid protein from bacteriophage PGHMIELC_01631 1497679.EP56_07555 1.2e-14 86.3 Listeriaceae Bacteria 1VMUX@1239,26MJA@186820,2ENIB@1,33G5R@2,4HR6R@91061 NA|NA|NA PGHMIELC_01632 936140.AEOT01000013_gene398 7.1e-08 63.2 Lactobacillaceae Bacteria 1U6Y3@1239,2DGA1@1,2ZV36@2,3F8PQ@33958,4IGS9@91061 NA|NA|NA PGHMIELC_01633 762051.LKI_09685 7.5e-108 397.1 Leuconostocaceae Bacteria 1V4MS@1239,2CIG6@1,3042M@2,4AXYR@81850,4HHBB@91061 NA|NA|NA PGHMIELC_01635 1497679.EP56_07575 7.7e-09 66.2 Listeriaceae Bacteria 1UZ30@1239,26M4V@186820,4HBNN@91061,COG2369@1,COG2369@2 NA|NA|NA S Phage minor capsid protein 2 PGHMIELC_01636 862514.HMPREF0623_0285 3.3e-36 159.1 Lactobacillaceae Bacteria 1UZ30@1239,3FBV4@33958,4HBNN@91061,COG2369@1,COG2369@2 NA|NA|NA S Phage minor capsid protein 2 PGHMIELC_01637 862514.HMPREF0623_0284 7.5e-113 414.5 Lactobacillaceae Bacteria 1UYMH@1239,2BX0Z@1,2Z88Q@2,3F75T@33958,4HC7J@91061 NA|NA|NA S Phage portal protein, SPP1 Gp6-like PGHMIELC_01638 862514.HMPREF0623_0283 4.6e-188 664.1 Bacilli Bacteria 1TT2C@1239,4HE0H@91061,COG1783@1,COG1783@2 NA|NA|NA S Phage terminase, large subunit, PBSX family PGHMIELC_01639 1423775.BAMN01000025_gene2809 3.6e-48 198.4 Lactobacillaceae Bacteria 1V6XW@1239,3F7DT@33958,4HIUS@91061,COG2963@1,COG2963@2 NA|NA|NA L transposase activity PGHMIELC_01640 220668.lp_2424 2.2e-17 94.7 Lactobacillaceae Bacteria 1VENI@1239,2EC8I@1,33670@2,3F8YU@33958,4HR98@91061 NA|NA|NA PGHMIELC_01641 220668.lp_2425 3.3e-17 93.6 Lactobacillaceae Bacteria 1W4M5@1239,2911N@1,2ZNP8@2,3F95E@33958,4I18X@91061 NA|NA|NA PGHMIELC_01644 220668.lp_0656 1.7e-81 308.5 Lactobacillaceae arpU Bacteria 1W30Q@1239,2DPRG@1,3333C@2,3F7WR@33958,4I13H@91061 NA|NA|NA S Phage transcriptional regulator, ArpU family PGHMIELC_01648 220668.lp_2433 5.9e-64 250.0 Lactobacillaceae rusA GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008821,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.1.22.4 ko:K01160 ko00000,ko01000,ko03400 Bacteria 1VFJ9@1239,3F8MJ@33958,4HQ3J@91061,COG4570@1,COG4570@2 NA|NA|NA L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC PGHMIELC_01649 220668.lp_2434 2.4e-63 248.4 Lactobacillaceae Bacteria 1U7BT@1239,29Q1G@1,30B01@2,3F9AZ@33958,4IH73@91061 NA|NA|NA PGHMIELC_01650 1423807.BACO01000085_gene2467 1e-64 253.4 Lactobacillaceae ps308 ko:K07741 ko00000 Bacteria 1UY80@1239,3F79X@33958,4HF9P@91061,COG3561@1,COG3561@2,COG3645@1,COG3645@2 NA|NA|NA K AntA/AntB antirepressor PGHMIELC_01651 60520.HR47_13590 1.6e-48 198.4 Lactobacillaceae Bacteria 1U7PZ@1239,29Q8U@1,30B7X@2,3FA00@33958,4IHMA@91061 NA|NA|NA PGHMIELC_01652 220668.lp_0643 9.3e-53 212.6 Lactobacillaceae Bacteria 1V6IW@1239,3FAFI@33958,4HJ9G@91061,COG3935@1,COG3935@2 NA|NA|NA L Domain of unknown function (DUF4373) PGHMIELC_01653 1138822.PL11_10310 5.6e-182 644.0 Lactobacillaceae ko:K06904 ko00000 Bacteria 1TSYM@1239,3F5ZB@33958,4HE4V@91061,COG3740@1,COG3740@2,COG4653@1,COG4653@2 NA|NA|NA S Phage capsid family PGHMIELC_01654 1423806.JCM15457_2547 3.5e-114 418.3 Lactobacillaceae Bacteria 1TP8B@1239,3F42D@33958,4HHWD@91061,COG4695@1,COG4695@2 NA|NA|NA S Phage portal protein PGHMIELC_01656 1423806.JCM15457_2549 1.8e-245 855.1 Lactobacillaceae terL Bacteria 1TPU1@1239,3F51U@33958,4HAXI@91061,COG4626@1,COG4626@2 NA|NA|NA S overlaps another CDS with the same product name PGHMIELC_01657 1423806.JCM15457_2550 9.5e-29 133.3 Lactobacillaceae Bacteria 1U8E3@1239,2BTDH@1,32NJJ@2,3FAVW@33958,4IIC1@91061 NA|NA|NA S Phage terminase, small subunit PGHMIELC_01658 1138822.PL11_10255 1.4e-15 89.4 Lactobacillaceae ko:K06877,ko:K07451 ko00000,ko01000,ko02048 Bacteria 1VA8J@1239,3F6BP@33958,4HNCA@91061,COG1403@1,COG1403@2 NA|NA|NA L Phage-associated protein PGHMIELC_01659 1423806.JCM15457_2536 3.6e-16 91.3 Lactobacillaceae Bacteria 1U8HW@1239,29QR7@1,30BR2@2,3FB02@33958,4IIFS@91061 NA|NA|NA PGHMIELC_01661 1423806.JCM15457_917 5.8e-30 138.3 Lactobacillaceae Bacteria 1U5PU@1239,2DKKN@1,309U4@2,3FAQE@33958,4II78@91061 NA|NA|NA PGHMIELC_01662 60520.HR47_09180 6.7e-28 130.6 Lactobacillaceae Bacteria 1U78W@1239,2DI7E@1,3028I@2,3F94R@33958,4IH3R@91061 NA|NA|NA PGHMIELC_01664 60520.HR47_13610 6.3e-69 266.5 Lactobacillaceae Bacteria 1U7J5@1239,29Q5Y@1,30B4U@2,3F9SU@33958,4IHFZ@91061 NA|NA|NA PGHMIELC_01665 220668.lp_2443 1.9e-14 84.0 Bacilli ko:K09946 ko00000 Bacteria 1U493@1239,4HZH1@91061,COG3422@1,COG3422@2 NA|NA|NA S Domain of unknown function (DUF1508) PGHMIELC_01666 60520.HR47_13630 3.1e-84 317.8 Lactobacillaceae Bacteria 1U6QG@1239,29BQP@1,2ZYP1@2,3F8AX@33958,4IGHP@91061 NA|NA|NA PGHMIELC_01667 220668.lp_2445 8.5e-53 212.6 Lactobacillaceae Bacteria 1U6JE@1239,29PGC@1,30AEH@2,3F815@33958,4IGBW@91061 NA|NA|NA PGHMIELC_01670 220668.lp_0635 5.8e-26 122.9 Lactobacillaceae Bacteria 1U79E@1239,2AGH0@1,316PJ@2,3F95G@33958,4IH49@91061 NA|NA|NA K Cro/C1-type HTH DNA-binding domain PGHMIELC_01671 220668.lp_0634 1.7e-37 161.4 Bacteria ko:K07729 ko00000,ko03000 Bacteria COG1476@1,COG1476@2 NA|NA|NA K sequence-specific DNA binding PGHMIELC_01674 1352230.S6C481_9CAUD 7.5e-22 110.5 Caudovirales Viruses 4QAQV@10239,4QPCB@28883,4QUPK@35237 NA|NA|NA S protein disulfide oxidoreductase activity PGHMIELC_01675 365048.Q0H245_9CAUD 3.6e-09 68.2 Caudovirales Viruses 4QCCB@10239,4QPUR@28883,4QX5A@35237 NA|NA|NA S Pfam:Peptidase_M78 PGHMIELC_01676 220668.lp_0625 8.5e-11 74.3 Lactobacillaceae ko:K15051 ko00000 Bacteria 1VD0S@1239,2DZEC@1,32V8J@2,3F4K6@33958,4HN7Y@91061 NA|NA|NA S DNA/RNA non-specific endonuclease PGHMIELC_01680 1400520.LFAB_07950 1.3e-11 76.6 Lactobacillaceae Bacteria 1VP04@1239,3F84E@33958,4HRP9@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain PGHMIELC_01685 1423724.BAMM01000012_gene1396 4.3e-40 171.8 Lactobacillaceae Bacteria 1V775@1239,28KYP@1,2ZAE6@2,3F6AR@33958,4HMWB@91061 NA|NA|NA S Domain of unknown function DUF1829 PGHMIELC_01686 220668.lp_2455 5.6e-219 766.5 Lactobacillaceae int Bacteria 1TPE1@1239,3F3NJ@33958,4HA65@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family PGHMIELC_01688 220668.lp_2457 8.9e-30 135.6 Lactobacillaceae Bacteria 1U6QM@1239,29PK9@1,30AIF@2,3F8B9@33958,4IGHW@91061 NA|NA|NA PGHMIELC_01690 220668.lp_2482 2e-38 164.5 Lactobacillaceae Bacteria 1U6G1@1239,2CH90@1,30ABZ@2,3F7U1@33958,4IG82@91061 NA|NA|NA PGHMIELC_01691 220668.lp_2483 1.4e-43 181.8 Lactobacillaceae Bacteria 1U6I5@1239,2A6J2@1,30VCN@2,3F7YQ@33958,4IGAG@91061 NA|NA|NA PGHMIELC_01692 220668.lp_2484 7.3e-83 313.2 Lactobacillaceae Bacteria 1U5IF@1239,3F617@33958,4IF98@91061,COG1846@1,COG1846@2 NA|NA|NA K MarR family PGHMIELC_01693 220668.lp_2485 0.0 1162.1 Lactobacillaceae bztC ko:K09971,ko:K21449 ko02010,map02010 M00232 ko00000,ko00001,ko00002,ko02000 1.B.40.2,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 Bacteria 1U5DQ@1239,3F5NM@33958,4IF55@91061,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation PGHMIELC_01694 220668.lp_2486 1.7e-309 1068.5 Lactobacillaceae Bacteria 1UWF2@1239,3F6D1@33958,4HGU0@91061,COG4932@1,COG4932@2 NA|NA|NA M MucBP domain PGHMIELC_01695 220668.lp_2488 2.7e-16 90.1 Lactobacillaceae Bacteria 1U8FW@1239,29QK0@1,32QG2@2,3FAXW@33958,4IIDR@91061 NA|NA|NA PGHMIELC_01696 220668.lp_2488a 7.2e-17 92.0 Lactobacillaceae Bacteria 1U79Q@1239,29QK0@1,30AYF@2,3F95V@33958,4IH4K@91061 NA|NA|NA PGHMIELC_01697 220668.lp_2488 6.5e-12 75.5 Lactobacillaceae Bacteria 1U8FW@1239,29QK0@1,32QG2@2,3FAXW@33958,4IIDR@91061 NA|NA|NA PGHMIELC_01698 220668.lp_2488c 1.1e-18 98.2 Lactobacillaceae Bacteria 1U889@1239,29QK0@1,30BJK@2,3FAP0@33958,4II61@91061 NA|NA|NA PGHMIELC_01699 220668.lp_2488f 1.6e-16 90.9 Lactobacillaceae Bacteria 1U8G5@1239,29QK0@1,32P7Y@2,3FAY3@33958,4IIDY@91061 NA|NA|NA PGHMIELC_01700 220668.lp_2488f 1.6e-16 90.9 Lactobacillaceae Bacteria 1U8G5@1239,29QK0@1,32P7Y@2,3FAY3@33958,4IIDY@91061 NA|NA|NA PGHMIELC_01701 1136177.KCA1_2033 1.9e-18 97.4 Lactobacillaceae Bacteria 1U889@1239,29QK0@1,30BJK@2,3FAP0@33958,4II61@91061 NA|NA|NA PGHMIELC_01702 220668.lp_2488h 1.6e-16 90.9 Lactobacillaceae Bacteria 1U864@1239,29QK0@1,30BIE@2,3FAKD@33958,4II3N@91061 NA|NA|NA PGHMIELC_01703 220668.lp_2497 0.0 1085.1 Lactobacillaceae msbA2 3.6.3.44 ko:K06147,ko:K18104 ko01501,ko02010,map01501,map02010 M00700 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 3.A.1.106,3.A.1.109,3.A.1.117,3.A.1.123,3.A.1.21 Bacteria 1TSY4@1239,3F5QW@33958,4HAJQ@91061,COG1132@1,COG1132@2 NA|NA|NA P ABC transporter transmembrane region PGHMIELC_01704 220668.lp_2498 2.9e-274 950.7 Lactobacillaceae tagE 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1V36G@1239,3FBE0@33958,4HJE7@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 PGHMIELC_01705 220668.lp_2499 0.0 1158.3 Lactobacillaceae macB3 ko:K02003,ko:K02004,ko:K05685 ko02010,map02010 M00258,M00709 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 Bacteria 1TPBJ@1239,3F44P@33958,4HBK7@91061,COG0577@1,COG0577@2,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein PGHMIELC_01706 60520.HR47_13790 6.8e-24 115.9 Lactobacillaceae Bacteria 1U80S@1239,29QFN@1,30BF1@2,3FAE4@33958,4IHY6@91061 NA|NA|NA PGHMIELC_01707 220668.lp_2502 1.1e-258 898.7 Lactobacillaceae pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 iLJ478.TM1385 Bacteria 1TP29@1239,3F3XK@33958,4H9VI@91061,COG0166@1,COG0166@2 NA|NA|NA G Belongs to the GPI family PGHMIELC_01708 220668.lp_2503 9.7e-155 552.7 Lactobacillaceae glcU ko:K05340,ko:K06216 ko00000,ko02000 2.A.7.5 Bacteria 1TQBN@1239,3F4K2@33958,4HAVH@91061,COG4975@1,COG4975@2 NA|NA|NA U sugar transport PGHMIELC_01709 220668.lp_2504 9.4e-217 759.2 Lactobacillaceae ywbD 2.1.1.191 ko:K06969 ko00000,ko01000,ko03009 Bacteria 1TRAJ@1239,3F49V@33958,4HAA1@91061,COG1092@1,COG1092@2 NA|NA|NA J S-adenosylmethionine-dependent methyltransferase PGHMIELC_01710 220668.lp_2505 2.9e-287 993.8 Lactobacillaceae yclK 2.7.13.3 ko:K02484,ko:K07636,ko:K07642 ko02020,map02020 M00434,M00450,M00645,M00646,M00648 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQ1H@1239,3FBSR@33958,4IS6U@91061,COG2770@1,COG2770@2,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase PGHMIELC_01711 220668.lp_2506 1.6e-134 485.3 Lactobacillaceae Bacteria 1TQUQ@1239,3F3QZ@33958,4HAXP@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator PGHMIELC_01712 220668.lp_2507 3e-243 847.4 Lactobacillaceae XK27_08635 ko:K09157 ko00000 Bacteria 1TQG8@1239,3F4H2@33958,4HBTU@91061,COG2848@1,COG2848@2 NA|NA|NA S UPF0210 protein PGHMIELC_01713 220668.lp_2508 2.3e-38 164.5 Lactobacillaceae gcvR ko:K07166 ko00000 Bacteria 1VENW@1239,3F811@33958,4HNJ4@91061,COG3830@1,COG3830@2 NA|NA|NA T Belongs to the UPF0237 family PGHMIELC_01714 220668.lp_2509 1.5e-169 602.1 Lactobacillaceae Bacteria 1TR6G@1239,3F423@33958,4HAMD@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family PGHMIELC_01716 220668.lp_2512 7.7e-92 343.2 Lactobacillaceae ko:K16923 M00582 ko00000,ko00002,ko02000 3.A.1.28 Bacteria 1VBHZ@1239,3FBKB@33958,4IR0C@91061,COG4720@1,COG4720@2 NA|NA|NA S ECF-type riboflavin transporter, S component PGHMIELC_01717 220668.lp_2513 8.6e-48 196.1 Lactobacillaceae Bacteria 1U6FW@1239,29PDQ@1,30ABW@2,3F7TQ@33958,4IG7V@91061 NA|NA|NA PGHMIELC_01718 220668.lp_2514 9.8e-214 749.2 Lactobacillaceae yceI ko:K08369 ko00000,ko02000 2.A.1 Bacteria 1TQM0@1239,3F3SE@33958,4HATA@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_01719 220668.lp_2515 1.9e-138 498.4 Lactobacillaceae 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 1TST7@1239,3F54T@33958,4HEFP@91061,COG1051@1,COG1051@2,COG4111@1,COG4111@2 NA|NA|NA F NUDIX domain PGHMIELC_01720 220668.lp_2516 3.8e-23 113.2 Lactobacillaceae Bacteria 1U6IV@1239,29PG1@1,30AE6@2,3F805@33958,4IGB8@91061 NA|NA|NA PGHMIELC_01722 220668.lp_2519 2.9e-159 567.8 Lactobacillaceae Bacteria 1UY1T@1239,3F5D8@33958,4I2Y3@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF915) PGHMIELC_01723 220668.lp_2520 2.8e-173 614.4 Lactobacillaceae ykfC 3.4.14.13 ko:K20742,ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1TSZ0@1239,3F5GI@33958,4HBUM@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family PGHMIELC_01724 220668.lp_2521 6.6e-81 306.6 Lactobacillaceae ko:K03719 ko00000,ko03000,ko03036 Bacteria 1V3MI@1239,3F6FN@33958,4HJUY@91061,COG1522@1,COG1522@2 NA|NA|NA K AsnC family PGHMIELC_01725 220668.lp_2522 2e-35 154.5 Lactobacillaceae Bacteria 1U6VE@1239,29PPI@1,30AMP@2,3F8JQ@33958,4IGPB@91061 NA|NA|NA PGHMIELC_01726 220668.lp_2523 5.1e-34 149.8 Lactobacillaceae Bacteria 1U6IW@1239,29PG2@1,30AE7@2,3F80G@33958,4IGBE@91061 NA|NA|NA PGHMIELC_01727 220668.lp_2524 7.8e-219 766.1 Lactobacillaceae 2.7.7.65 ko:K20955 ko05111,map05111 ko00000,ko00001,ko01000 Bacteria 1TSW8@1239,3F4R9@33958,4HBT1@91061,COG2199@1,COG3706@2 NA|NA|NA T diguanylate cyclase PGHMIELC_01728 220668.lp_2525 7.8e-296 1022.3 Lactobacillaceae ko:K06158 ko00000,ko03012 Bacteria 1TPAX@1239,3F3QI@33958,4HBVV@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein PGHMIELC_01729 220668.lp_2526 2e-106 391.7 Lactobacillaceae 3.2.2.20 ko:K01246,ko:K06977 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V7GR@1239,3F44B@33958,4HJ11@91061,COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase PGHMIELC_01730 220668.lp_2528 1.5e-82 312.0 Lactobacillaceae Bacteria 1V7D7@1239,3F6XZ@33958,4HIGP@91061,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PGHMIELC_01731 220668.lp_2529 2.7e-39 167.9 Lactobacillaceae Bacteria 1U7MB@1239,29Q78@1,30B69@2,3F9WG@33958,4IHIG@91061 NA|NA|NA PGHMIELC_01732 220668.lp_2531 0.0 1261.9 Lactobacillaceae nagE GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0008643,GO:0009401,GO:0009987,GO:0015144,GO:0015764,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0033554,GO:0034219,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071702,GO:0090563,GO:0090586,GO:1901264 2.7.1.193,2.7.1.199,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K02808,ko:K02809,ko:K02810,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00267,M00268,M00269,M00270,M00271,M00272,M00303,M00806,M00809 R00811,R02738,R02780,R04111,R04394,R05132,R05199,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.13,4.A.1.1.14,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.1.9,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 iECP_1309.ECP_0691,iSB619.SA_RS08720 Bacteria 1TPJ8@1239,3F44V@33958,4HA8X@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system, EIIB PGHMIELC_01733 220668.lp_2532 4.4e-140 503.8 Lactobacillaceae panE1 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSZ1@1239,3F455@33958,4HB4T@91061,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid PGHMIELC_01734 60520.HR47_13920 1.7e-41 174.9 Lactobacillaceae panE1 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSZ1@1239,3F455@33958,4HB4T@91061,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid PGHMIELC_01735 220668.lp_2534 5e-162 577.0 Lactobacillaceae degV Bacteria 1VUI4@1239,3F5VF@33958,4HVVF@91061,COG1307@1,COG1307@2 NA|NA|NA S Uncharacterised protein, DegV family COG1307 PGHMIELC_01736 220668.lp_2535 1.5e-231 808.5 Lactobacillaceae hom1 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ2H@1239,3F3KS@33958,4HBAP@91061,COG0460@1,COG0460@2 NA|NA|NA E Homoserine dehydrogenase PGHMIELC_01737 220668.lp_2536 2.6e-244 850.9 Lactobacillaceae metY 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 Bacteria 1VYCY@1239,3FBSS@33958,4H9X5@91061,COG2873@1,COG2873@2 NA|NA|NA E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol PGHMIELC_01738 220668.lp_2537 4.8e-165 587.0 Lactobacillaceae metAA GO:0003674,GO:0003824,GO:0008374,GO:0008899,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS11970 Bacteria 1TQVR@1239,3F5CA@33958,4H9W4@91061,COG1897@1,COG1897@2 NA|NA|NA E Transfers an acetyl group from acetyl-CoA to PGHMIELC_01739 220668.lp_2541 1.4e-176 625.5 Lactobacillaceae XK27_08835 ko:K01989,ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPB0@1239,3F462@33958,4HESK@91061,COG2984@1,COG2984@2 NA|NA|NA S ABC transporter PGHMIELC_01740 220668.lp_2542 8.7e-154 549.7 Lactobacillaceae XK27_08840 ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPDJ@1239,3F40J@33958,4HBMY@91061,COG4120@1,COG4120@2 NA|NA|NA U Belongs to the binding-protein-dependent transport system permease family PGHMIELC_01741 220668.lp_2543 6.4e-137 493.4 Lactobacillaceae XK27_08845 ko:K05833 M00247 ko00000,ko00002,ko02000 Bacteria 1TPAN@1239,3F3NW@33958,4HCHC@91061,COG1101@1,COG1101@2 NA|NA|NA S ABC transporter, ATP-binding protein PGHMIELC_01742 220668.lp_2544 7.4e-258 896.0 Lactobacillaceae npr 1.11.1.1 ko:K05910 ko00000,ko01000 Bacteria 1TPWW@1239,3F449@33958,4H9U7@91061,COG0446@1,COG0446@2 NA|NA|NA C NADH oxidase PGHMIELC_01743 220668.lp_2548 1.5e-158 565.5 Lactobacillaceae glxR 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 iJN678.mmsB Bacteria 1TR4F@1239,3F3XC@33958,4H9MA@91061,COG2084@1,COG2084@2 NA|NA|NA I Dehydrogenase PGHMIELC_01744 220668.lp_2549 4.8e-137 493.8 Lactobacillaceae terC ko:K05794 ko00000 Bacteria 1UVIJ@1239,3F3WS@33958,4HEKW@91061,COG0861@1,COG0861@2 NA|NA|NA P membrane PGHMIELC_01745 220668.lp_2550 1.2e-84 319.3 Lactobacillaceae maa 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 ko00000,ko01000 Bacteria 1TQEX@1239,3FBEK@33958,4IPXR@91061,COG0110@1,COG0110@2 NA|NA|NA S Maltose acetyltransferase PGHMIELC_01746 220668.lp_2551 3.3e-200 704.1 Lactobacillaceae hisC 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TPUV@1239,3F466@33958,4HA1H@91061,COG0079@1,COG0079@2 NA|NA|NA E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily PGHMIELC_01747 220668.lp_2552 7.6e-52 209.5 Lactobacillaceae hisE GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16 ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04640 RC00002,RC00945,RC01055 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS14110,iYO844.BSU34860 Bacteria 1VB6S@1239,3F7V5@33958,4HKDY@91061,COG0140@1,COG0140@2 NA|NA|NA E phosphoribosyl-ATP diphosphatase activity PGHMIELC_01748 220668.lp_2553 2.5e-58 231.1 Lactobacillaceae hisI GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.5.4.25,3.6.1.31,5.3.1.16 ko:K01496,ko:K01497,ko:K01814,ko:K11755 ko00340,ko00740,ko00790,ko01100,ko01110,ko01230,ko02024,map00340,map00740,map00790,map01100,map01110,map01230,map02024 M00026,M00125 R00425,R04035,R04037,R04640 RC00002,RC00293,RC00945,RC01055,RC02504 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_0880,iECW_1372.ECW_m2186,iEKO11_1354.EKO11_1768,iHN637.CLJU_RS05760,iSB619.SA_RS14110,iUMN146_1321.UM146_06665,iWFL_1372.ECW_m2186 Bacteria 1UYNA@1239,3F73W@33958,4HA9R@91061,COG0139@1,COG0139@2 NA|NA|NA E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP PGHMIELC_01749 220668.lp_2554 6.4e-134 483.4 Lactobacillaceae hisF GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 3.5.4.19,3.6.1.31 ko:K01663,ko:K02500,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04558 RC00002,RC00010,RC01055,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 iECO111_1330.ECO111_2749,iEcolC_1368.EcolC_1617,iHN637.CLJU_RS05755,iLJ478.TM1036,iSB619.SA_RS14115,iYL1228.KPN_02481 Bacteria 1TP0W@1239,3F3XV@33958,4HAAM@91061,COG0107@1,COG0107@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit PGHMIELC_01750 220668.lp_2556 3.5e-129 467.6 Lactobacillaceae hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0388 Bacteria 1V1IR@1239,3F5YT@33958,4HACP@91061,COG0106@1,COG0106@2 NA|NA|NA E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase PGHMIELC_01751 220668.lp_2557 4.1e-110 404.1 Lactobacillaceae hisH ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQT0@1239,3F5AD@33958,4HHNQ@91061,COG0118@1,COG0118@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR PGHMIELC_01752 220668.lp_2558 7.9e-108 396.4 Lactobacillaceae hisB GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,2.6.1.9,3.1.3.15,4.2.1.19 ko:K00013,ko:K00817,ko:K01089,ko:K01693 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R01158,R01163,R03012,R03013,R03243,R03457 RC00006,RC00017,RC00099,RC00242,RC00463,RC00888,RC00932 ko00000,ko00001,ko00002,ko01000,ko01007 iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iLJ478.TM1039,iSB619.SA_RS14130,iUMNK88_1353.UMNK88_2570 Bacteria 1TRH7@1239,3F4TQ@33958,4HCFG@91061,COG0131@1,COG0131@2 NA|NA|NA E imidazoleglycerol-phosphate dehydratase PGHMIELC_01753 220668.lp_2559 1.2e-233 815.5 Lactobacillaceae hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 ko:K00013,ko:K15509 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAW@1239,3F40P@33958,4H9XK@91061,COG0141@1,COG0141@2 NA|NA|NA E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine PGHMIELC_01754 220668.lp_2560 4.3e-118 430.6 Lactobacillaceae hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSVZ@1239,3F4WT@33958,4H9MH@91061,COG0040@1,COG0040@2 NA|NA|NA F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity PGHMIELC_01755 220668.lp_2561 1.3e-215 755.4 Lactobacillaceae hisZ 2.4.2.17,6.1.1.21 ko:K00765,ko:K01892,ko:K02502 ko00340,ko00970,ko01100,ko01110,ko01230,map00340,map00970,map01100,map01110,map01230 M00026,M00359,M00360 R01071,R03655 RC00055,RC00523,RC02819,RC03200 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPZZ@1239,3F4W1@33958,4HBBA@91061,COG3705@1,COG3705@2 NA|NA|NA E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine PGHMIELC_01756 220668.lp_2563 3.2e-163 580.9 Lactobacillaceae hisK 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQQX@1239,3F4WG@33958,4H9P1@91061,COG1387@1,COG1387@2 NA|NA|NA E Histidinol phosphate phosphatase, HisJ PGHMIELC_01757 220668.lp_2564 4.6e-216 756.9 Lactobacillaceae ysaA Bacteria 1V04Y@1239,3F3SH@33958,4HDS5@91061,COG4767@1,COG4767@2 NA|NA|NA V RDD family PGHMIELC_01758 220668.lp_2565 7.6e-166 589.7 Lactobacillaceae corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1TPI8@1239,3F4B8@33958,4HE7S@91061,COG0598@1,COG0598@2 NA|NA|NA P CorA-like Mg2+ transporter protein PGHMIELC_01759 1136177.KCA1_2093 3.4e-50 204.1 Lactobacillaceae ko:K05937 ko00000 Bacteria 1U6GV@1239,3F7W5@33958,4IG91@91061,COG5646@1,COG5646@2 NA|NA|NA S Domain of unknown function (DU1801) PGHMIELC_01760 1136177.KCA1_2094 3.5e-13 80.5 Lactobacillaceae rmeB Bacteria 1V3QI@1239,3F69R@33958,4HH53@91061,COG0789@1,COG0789@2 NA|NA|NA K transcriptional regulator, MerR family PGHMIELC_01761 220668.lp_2570 8e-199 699.5 Lactobacillaceae asd 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC6@1239,3F4S9@33958,4HA9H@91061,COG0136@1,COG0136@2 NA|NA|NA E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate PGHMIELC_01762 220668.lp_2572 2e-185 654.8 Lactobacillaceae pva3 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 1TPZS@1239,3F3RA@33958,4HEQ3@91061,COG3049@1,COG3049@2 NA|NA|NA M Linear amide C-N hydrolase, choloylglycine hydrolase family protein PGHMIELC_01763 220668.lp_2573 3.7e-34 150.2 Lactobacillaceae Bacteria 1U6AC@1239,2A2W9@1,30RAC@2,3F7FP@33958,4IG1N@91061 NA|NA|NA PGHMIELC_01764 220668.lp_2574 3.2e-112 411.4 Lactobacillaceae Bacteria 1U544@1239,3F4HQ@33958,4IEVF@91061,COG3548@1,COG3548@2 NA|NA|NA S Protein of unknown function (DUF1211) PGHMIELC_01765 220668.lp_2575 0.0 1565.4 Lactobacillaceae ydgH ko:K06994,ko:K07003 ko00000 Bacteria 1TQ7C@1239,3FCCY@33958,4HBM6@91061,COG2409@1,COG2409@2 NA|NA|NA S MMPL family PGHMIELC_01766 220668.lp_2578 7.2e-289 999.6 Lactobacillaceae Bacteria 1TQBI@1239,3F4FM@33958,4HBAT@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein PGHMIELC_01767 220668.lp_2579 1.1e-74 285.8 Lactobacillaceae yjcF ko:K02348 ko00000 Bacteria 1VA2J@1239,3F6HQ@33958,4HKF5@91061,COG2153@1,COG2153@2 NA|NA|NA S Acetyltransferase (GNAT) domain PGHMIELC_01768 220668.lp_2580 0.0 1383.6 Lactobacillaceae ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 R05081,R10849 RC00017 ko00000,ko00001,ko01000 Bacteria 1TRMA@1239,3F3R7@33958,4H9S0@91061,COG1368@1,COG1368@2 NA|NA|NA M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily PGHMIELC_01769 220668.lp_2582 0.0 1082.0 Lactobacillaceae glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1UG1C@1239,3F3SZ@33958,4HCPQ@91061,COG0584@1,COG0584@2,COG4781@1,COG4781@2 NA|NA|NA C phosphodiesterase PGHMIELC_01770 220668.lp_2585 2.3e-184 651.4 Lactobacillaceae trxB1 1.18.1.2,1.19.1.1 ko:K21567 ko00000,ko01000 Bacteria 1TRPN@1239,3F3NQ@33958,4H9V7@91061,COG0492@1,COG0492@2 NA|NA|NA C Ferredoxin--NADP reductase PGHMIELC_01771 220668.lp_2586 4.4e-143 513.8 Lactobacillaceae Bacteria 1VXHZ@1239,3F75V@33958,4HX59@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF915) PGHMIELC_01772 220668.lp_2588 6.2e-182 644.0 Lactobacillaceae 3.6.4.13 ko:K03496,ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036,ko04812 Bacteria 1UIXJ@1239,3F6DZ@33958,4I0W9@91061,COG3827@1,COG3827@2 NA|NA|NA S domain, Protein PGHMIELC_01773 220668.lp_2589 3.6e-168 597.4 Lactobacillaceae Bacteria 1TQQR@1239,3FBA4@33958,4HHU5@91061,COG2326@1,COG2326@2 NA|NA|NA S Polyphosphate kinase 2 (PPK2) PGHMIELC_01774 220668.lp_2590 2.5e-98 364.8 Lactobacillaceae drgA Bacteria 1UYJU@1239,3F5ZD@33958,4HBVQ@91061,COG0778@1,COG0778@2 NA|NA|NA C Nitroreductase family PGHMIELC_01775 220668.lp_2591 3.1e-178 630.9 Lactobacillaceae iunH2 3.2.2.1 ko:K01239,ko:K01250 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 Bacteria 1TSAR@1239,3F4A3@33958,4HDCS@91061,COG1957@1,COG1957@2 NA|NA|NA F nucleoside hydrolase PGHMIELC_01776 220668.lp_2593 3.4e-150 537.7 Lactobacillaceae rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469,ko:K06993 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1V4A0@1239,3F3RG@33958,4HHJ9@91061,COG0328@1,COG0328@2,COG3341@1,COG3341@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids PGHMIELC_01777 220668.lp_2594 3.1e-153 547.7 Lactobacillaceae glcU ko:K05340,ko:K06216 ko00000,ko02000 2.A.7.5 Bacteria 1TQBN@1239,3F4K2@33958,4HAVH@91061,COG4975@1,COG4975@2 NA|NA|NA U sugar transport PGHMIELC_01778 220668.lp_2595 5.9e-73 280.0 Lactobacillaceae bglK_1 Bacteria 1TRQ7@1239,3F3ZI@33958,4HE30@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family PGHMIELC_01779 220668.lp_2595 3.1e-89 334.3 Lactobacillaceae bglK_1 Bacteria 1TRQ7@1239,3F3ZI@33958,4HE30@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family PGHMIELC_01780 220668.lp_2596 3.7e-156 557.4 Lactobacillaceae pflC 1.97.1.4 ko:K04069 R04710 ko00000,ko01000 Bacteria 1TPK2@1239,3F472@33958,4HACV@91061,COG1180@1,COG1180@2 NA|NA|NA C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine PGHMIELC_01781 220668.lp_2597 3.7e-134 484.2 Lactobacillaceae yciT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 Bacteria 1TNYH@1239,3F5M5@33958,4HC6X@91061,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain PGHMIELC_01782 220668.lp_2598 0.0 1645.9 Lactobacillaceae ybiW GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 Bacteria 1TPTF@1239,3FCBM@33958,4HATB@91061,COG1882@1,COG1882@2 NA|NA|NA C Pyruvate formate lyase-like PGHMIELC_01783 220668.lp_2599 1.8e-178 631.7 Lactobacillaceae Bacteria 1TPUB@1239,3F4PP@33958,4HCAR@91061,COG2390@1,COG2390@2 NA|NA|NA K sugar-binding domain protein PGHMIELC_01784 220668.lp_2600 1.5e-124 452.2 Lactobacillaceae tal 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4Q@1239,3F4Q8@33958,4HA8G@91061,COG0176@1,COG0176@2 NA|NA|NA H Transaldolase/Fructose-6-phosphate aldolase PGHMIELC_01785 220668.lp_2601 4.2e-141 507.3 Lactobacillaceae Bacteria 1TSZZ@1239,3F4XA@33958,4HB54@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase PGHMIELC_01786 220668.lp_2602 6.4e-176 623.2 Lactobacillaceae ccpB 5.1.1.1 ko:K01775,ko:K05499 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011,ko03000 Bacteria 1TQSQ@1239,3F4YI@33958,4HBNR@91061,COG1609@1,COG1609@2 NA|NA|NA K lacI family PGHMIELC_01787 220668.lp_2603 1e-156 559.3 Lactobacillaceae Bacteria 1V5GV@1239,3F5EG@33958,4HHPG@91061,COG1737@1,COG1737@2 NA|NA|NA K Helix-turn-helix domain, rpiR family PGHMIELC_01788 220668.lp_2604 7.9e-177 626.3 Lactobacillaceae ko:K22230 ko00562,ko01120,map00562,map01120 R09954 RC00182 ko00000,ko00001,ko01000 Bacteria 1TQSS@1239,3FCE8@33958,4HDXF@91061,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold PGHMIELC_01789 220668.lp_2606 5.9e-199 699.9 Lactobacillaceae yhhX 1.1.1.371 ko:K16044 ko00562,ko01120,map00562,map01120 R09954 RC00182 ko00000,ko00001,ko01000 Bacteria 1TR8S@1239,3F4QU@33958,4HBHI@91061,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain PGHMIELC_01790 220668.lp_2608 0.0 1211.1 Lactobacillaceae yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 1TR4G@1239,3F42V@33958,4HBJR@91061,COG0025@1,COG0025@2 NA|NA|NA P Sodium proton antiporter PGHMIELC_01791 220668.lp_2610 5.7e-280 969.5 Lactobacillaceae dxs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP37@1239,3F4RN@33958,4H9QW@91061,COG1154@1,COG1154@2 NA|NA|NA H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) PGHMIELC_01792 220668.lp_2612 3.7e-107 394.0 Lactobacillaceae pncA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 ko:K16788 ko00000,ko02000 2.A.88.5 iSB619.SA_RS09955 Bacteria 1V1CY@1239,3F41F@33958,4HFRS@91061,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family PGHMIELC_01793 220668.lp_2613 2.7e-132 478.0 Lactobacillaceae Bacteria 1U5IX@1239,29NT4@1,309R6@2,3F624@33958,4HZ1H@91061 NA|NA|NA PGHMIELC_01794 220668.lp_2614 5.1e-125 453.8 Lactobacillaceae skfE ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPUP@1239,3FC3H@33958,4HGHM@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter PGHMIELC_01795 220668.lp_2615 9.5e-65 252.7 Lactobacillaceae yvoA_1 ko:K07979 ko00000,ko03000 Bacteria 1VA2B@1239,3F6GC@33958,4HPK4@91061,COG1725@1,COG1725@2 NA|NA|NA K Transcriptional regulator, GntR family PGHMIELC_01796 220668.lp_2616 1.2e-45 188.7 Lactobacillaceae Bacteria 1U669@1239,2CK4C@1,30266@2,3F764@33958,4IFWF@91061 NA|NA|NA S Enterocin A Immunity PGHMIELC_01797 220668.lp_2620 7e-175 619.8 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TQYU@1239,3F43H@33958,4HC4H@91061,COG1073@1,COG1073@2 NA|NA|NA D Alpha beta PGHMIELC_01798 220668.lp_2621 0.0 1186.8 Lactobacillaceae pepF2 ko:K08602 ko00000,ko01000,ko01002 Bacteria 1TQ5W@1239,3F4ZV@33958,4HAN9@91061,COG1164@1,COG1164@2 NA|NA|NA E Oligopeptidase F PGHMIELC_01799 220668.lp_2622 1.3e-72 278.9 Lactobacillaceae Bacteria 1VEC4@1239,3F654@33958,4HM2F@91061,COG1396@1,COG1396@2 NA|NA|NA K Transcriptional regulator PGHMIELC_01800 220668.lp_2623 3e-164 584.3 Lactobacillaceae Bacteria 1VQQ8@1239,2E39Q@1,32Y99@2,3F4UX@33958,4HRY1@91061 NA|NA|NA PGHMIELC_01801 220668.lp_2624 1.3e-57 228.8 Lactobacillaceae Bacteria 1U6FB@1239,29PD5@1,30ABC@2,3F7SH@33958,4IG76@91061 NA|NA|NA PGHMIELC_01802 220668.lp_2625 2.6e-48 197.6 Lactobacillaceae Bacteria 1U83C@1239,2AXGE@1,31PG2@2,3FAH7@33958,4II0S@91061 NA|NA|NA PGHMIELC_01803 220668.lp_2629 0.0 1152.1 Lactobacillaceae poxB 1.2.3.3,1.2.5.1 ko:K00156,ko:K00158 ko00620,ko01100,map00620,map01100 R00207,R03145 RC00860,RC02745 ko00000,ko00001,ko01000 Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family PGHMIELC_01804 220668.lp_2630 5.4e-68 263.5 Lactobacillaceae Bacteria 1U64R@1239,29P52@1,30A39@2,3F71Q@33958,4IFUA@91061 NA|NA|NA PGHMIELC_01805 220668.lp_2631 8.4e-145 519.6 Lactobacillaceae yjfP GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0034338,GO:0052689 ko:K06889 ko00000 Bacteria 1TTC0@1239,3F3XJ@33958,4IBNH@91061,COG1073@1,COG1073@2 NA|NA|NA S Dienelactone hydrolase family PGHMIELC_01806 220668.lp_2633 6.6e-56 223.0 Lactobacillaceae dsbJ 2.7.1.180,5.3.4.1 ko:K01829,ko:K03671,ko:K03734,ko:K06196 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko02000,ko03110 5.A.1.2 Bacteria 1VAS6@1239,3F72K@33958,4HKGM@91061,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin PGHMIELC_01807 220668.lp_2634 4.2e-206 723.8 Lactobacillaceae metB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 2.5.1.48,4.4.1.8 ko:K01739,ko:K01760 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC7@1239,3F4CK@33958,4HAFQ@91061,COG0626@1,COG0626@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme PGHMIELC_01808 220668.lp_2635 5.2e-47 193.4 Lactobacillaceae Bacteria 1U637@1239,29P3W@1,30A23@2,3F6XJ@33958,4IFSI@91061 NA|NA|NA PGHMIELC_01809 220668.lp_2636 6.3e-45 187.6 Lactobacillaceae Bacteria 1U5NY@1239,29NVK@1,309TP@2,3F68R@33958,4IFDG@91061 NA|NA|NA PGHMIELC_01810 220668.lp_2638 5e-82 310.5 Lactobacillaceae yybC Bacteria 1UPWN@1239,2BWFV@1,32QWV@2,3F59W@33958,4HXPC@91061 NA|NA|NA S Protein of unknown function (DUF2798) PGHMIELC_01811 220668.lp_2641 1.7e-73 282.0 Lactobacillaceae Bacteria 1UFZH@1239,29V33@1,30GGE@2,3F5BQ@33958,4IF1H@91061 NA|NA|NA PGHMIELC_01812 220668.lp_2642 4e-60 237.3 Lactobacillaceae Bacteria 1U5WQ@1239,29P7Q@1,309XV@2,3F6MJ@33958,4IFK6@91061 NA|NA|NA PGHMIELC_01813 220668.lp_2643 5.1e-195 686.8 Lactobacillaceae lplA 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 Bacteria 1TQ5U@1239,3F4UZ@33958,4H9P6@91061,COG0095@1,COG0095@2 NA|NA|NA H Lipoate-protein ligase PGHMIELC_01814 220668.lp_2645 0.0 1119.0 Lactobacillaceae acm2 3.2.1.17 ko:K01185,ko:K02395 ko00000,ko01000,ko02035 Bacteria 1V7JY@1239,3FC1A@33958,4HIVW@91061,COG1705@1,COG1705@2 NA|NA|NA NU Bacterial SH3 domain PGHMIELC_01815 220668.lp_2647 3e-72 277.7 Lactobacillaceae ko:K02744 ko00052,ko02060,map00052,map02060 M00277,M00287 R08366,R08367 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1.4,4.A.6.1.5 Bacteria 1VES9@1239,3F7KK@33958,4IQPB@91061,COG2893@1,COG2893@2 NA|NA|NA G PTS system fructose IIA component PGHMIELC_01816 220668.lp_2648 3.2e-147 527.7 Lactobacillaceae ko:K02796,ko:K10986 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00287 R02630,R08367 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.5 Bacteria 1TQA3@1239,3F4YA@33958,4HD65@91061,COG3716@1,COG3716@2 NA|NA|NA G PTS system mannose/fructose/sorbose family IID component PGHMIELC_01817 220668.lp_2649 3.1e-142 511.1 Lactobacillaceae agaC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 ko:K10985 ko00052,ko02060,map00052,map02060 M00287 R08367 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1.5 Bacteria 1TPKK@1239,3F4YT@33958,4HC0V@91061,COG3715@1,COG3715@2 NA|NA|NA G PTS system sorbose-specific iic component PGHMIELC_01818 220668.lp_2650 1.2e-85 322.4 Lactobacillaceae agaB 2.7.1.191 ko:K02794,ko:K10984 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00287 R02630,R08367 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1,4.A.6.1.5 iB21_1397.B21_02956,iEC55989_1330.EC55989_3558,iECBD_1354.ECBD_0602,iECB_1328.ECB_03005,iECD_1391.ECD_03005,iECIAI1_1343.ECIAI1_3288,iECIAI39_1322.ECIAI39_3639,iECO103_1326.ECO103_3885,iECO111_1330.ECO111_3962,iECO26_1355.ECO26_4243,iECSE_1348.ECSE_3424,iECW_1372.ECW_m3408,iEKO11_1354.EKO11_0579,iEcE24377_1341.EcE24377A_3620,iEcSMS35_1347.EcSMS35_3437,iEcolC_1368.EcolC_0560,iUMNK88_1353.UMNK88_3897,iWFL_1372.ECW_m3408 Bacteria 1TQJ4@1239,3F5PA@33958,4HI37@91061,COG3444@1,COG3444@2 NA|NA|NA K PTS system sorbose subfamily IIB component PGHMIELC_01819 220668.lp_2651 2e-129 468.4 Lactobacillaceae ko:K03710 ko00000,ko03000 Bacteria 1UIXK@1239,3F68S@33958,4ISVV@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA domain PGHMIELC_01820 220668.lp_2652 1.6e-79 302.0 Lactobacillaceae uspA ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1VEJR@1239,3F4Z0@33958,4HNHG@91061,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein PGHMIELC_01821 220668.lp_2653 1.9e-156 558.5 Lactobacillaceae rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 Bacteria 1TSM6@1239,3F50K@33958,4HA7M@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil PGHMIELC_01822 220668.lp_2654 1.7e-48 198.4 Lactobacillaceae Bacteria 1V3D7@1239,3F83A@33958,4IGD5@91061,COG1396@1,COG1396@2 NA|NA|NA K Cro/C1-type HTH DNA-binding domain PGHMIELC_01823 60520.HR47_14325 3.3e-21 107.1 Lactobacillaceae Bacteria 1U81Q@1239,29QG6@1,30BFM@2,3FAF3@33958,4IHZ3@91061 NA|NA|NA S Protein of unknown function (DUF2929) PGHMIELC_01824 220668.lp_2658 1e-223 782.3 Lactobacillaceae lsgC Bacteria 1TPHK@1239,3F5EZ@33958,4HAXV@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 PGHMIELC_01825 220668.lp_2659 0.0 1640.6 Lactobacillaceae xfp 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 Bacteria 1TR23@1239,3F3TZ@33958,4HC2J@91061,COG3957@1,COG3957@2 NA|NA|NA G Phosphoketolase PGHMIELC_01826 220668.lp_2660 4e-161 573.9 Lactobacillaceae Bacteria 1TPA9@1239,3F57H@33958,4HD64@91061,COG0627@1,COG0627@2 NA|NA|NA S Putative esterase PGHMIELC_01827 220668.lp_2661 2.4e-130 471.5 Lactobacillaceae gntR2 ko:K03486,ko:K03492,ko:K03710 ko00000,ko03000 Bacteria 1V0UW@1239,3FBE1@33958,4IPQ0@91061,COG2188@1,COG2188@2 NA|NA|NA K Transcriptional regulator PGHMIELC_01828 220668.lp_2662 5.8e-91 340.1 Lactobacillaceae ybaK ko:K03976 ko00000,ko01000,ko03016 Bacteria 1V6JF@1239,3F5H1@33958,4HHVB@91061,COG2606@1,COG2606@2 NA|NA|NA S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily PGHMIELC_01829 220668.lp_2663 2e-138 498.4 Lactobacillaceae Bacteria 1V5G2@1239,31PIN@2,3F6X9@33958,4HIRV@91061,arCOG05209@1 NA|NA|NA PGHMIELC_01830 220668.lp_2664 1.4e-116 425.6 Lactobacillaceae ypgQ ko:K06950 ko00000 Bacteria 1V7IZ@1239,3F3PN@33958,4HIVB@91061,COG1418@1,COG1418@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. PGHMIELC_01831 220668.lp_2665 5.5e-138 496.9 Lactobacillaceae rrp8 ko:K07707 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko02022 Bacteria 1U5HV@1239,3F5ZC@33958,4IF8N@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain PGHMIELC_01832 220668.lp_2666 4.2e-92 344.0 Lactobacillaceae M1-874 ko:K13638,ko:K13640 ko00000,ko03000 Bacteria 1V7Z4@1239,3F5IX@33958,4HJXK@91061,COG0789@1,COG0789@2 NA|NA|NA K Domain of unknown function (DUF1836) PGHMIELC_01833 220668.lp_2667 4.5e-61 240.4 Lactobacillaceae Bacteria 1VZWZ@1239,2CICD@1,3462T@2,3F6T8@33958,4HY4B@91061 NA|NA|NA PGHMIELC_01834 220668.lp_2668 7e-74 283.1 Lactobacillaceae hspX GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 1U5MK@1239,3F677@33958,4IFCD@91061,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family PGHMIELC_01835 220668.lp_2669 4.4e-58 230.3 Lactobacillaceae Bacteria 1U6KN@1239,29PHG@1,30AFM@2,3F83U@33958,4IGDE@91061 NA|NA|NA PGHMIELC_01836 220668.lp_2671 1.8e-240 838.2 Lactobacillaceae yhdP ko:K03699,ko:K06189 ko00000,ko02000,ko02042 9.A.40.1.2 Bacteria 1TPN0@1239,3F3TX@33958,4H9SB@91061,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain PGHMIELC_01837 220668.lp_2673 4.9e-87 327.0 Lactobacillaceae nrdI ko:K03647 ko00000 Bacteria 1V71V@1239,3F6JF@33958,4HIW7@91061,COG1780@1,COG1780@2 NA|NA|NA F Belongs to the NrdI family PGHMIELC_01838 220668.lp_2674 2.6e-270 937.6 Lactobacillaceae yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 1TR4G@1239,3F42V@33958,4HBJR@91061,COG0025@1,COG0025@2 NA|NA|NA P Sodium proton antiporter PGHMIELC_01839 220668.lp_2675 1.1e-212 745.7 Lactobacillaceae yttB Bacteria 1TPJ6@1239,3F4F9@33958,4HAGJ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_01840 220668.lp_2676 1.2e-61 242.3 Lactobacillaceae Bacteria 1U7JK@1239,3F9TS@33958,4IHGP@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance PGHMIELC_01841 220668.lp_2677 5.1e-173 613.6 Lactobacillaceae Bacteria 1TQ0M@1239,3F9BC@33958,4I2RV@91061,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase PGHMIELC_01842 220668.lp_2680 8.5e-57 226.1 Lactobacillaceae Bacteria 1U64W@1239,29F74@1,3024T@2,3F720@33958,4IFUM@91061 NA|NA|NA S SdpI/YhfL protein family PGHMIELC_01843 220668.lp_2681 6.3e-295 1019.2 Lactobacillaceae zwf GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 iIT341.HP1101 Bacteria 1TPYF@1239,3F48G@33958,4HA73@91061,COG0364@1,COG0364@2 NA|NA|NA G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone PGHMIELC_01844 220668.lp_2683 5.5e-261 906.4 Lactobacillaceae gabR ko:K00375 ko00000,ko03000 Bacteria 1TPS5@1239,3F5UY@33958,4HB2U@91061,COG1167@1,COG1167@2 NA|NA|NA K Bacterial regulatory proteins, gntR family PGHMIELC_01845 220668.lp_2684 1.4e-217 761.9 Lactobacillaceae patA 2.6.1.1 ko:K00812,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00525 R00355,R00694,R00734,R00896,R02433,R02619,R04467,R05052 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase PGHMIELC_01846 220668.lp_2685 4e-104 384.4 Lactobacillaceae dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCK@1239,3F4UH@33958,4H9K9@91061,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) PGHMIELC_01847 1114972.AUAW01000027_gene735 3e-18 96.7 Lactobacillaceae Bacteria 1U8CI@1239,29QNC@1,30BN0@2,3FAU7@33958,4IIAH@91061 NA|NA|NA PGHMIELC_01848 220668.lp_2688 1.7e-126 458.8 Lactobacillaceae ko:K07090 ko00000 Bacteria 1VR9G@1239,3F3TR@33958,4HV4W@91061,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein PGHMIELC_01849 220668.lp_2689 1.9e-161 575.1 Lactobacillaceae mleR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 Bacteria 1V5VW@1239,3F5D2@33958,4HHDY@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR family PGHMIELC_01850 220668.lp_2690 5.6e-115 420.2 Lactobacillaceae ylbE Bacteria 1TQFS@1239,3F521@33958,4HDA2@91061,COG0702@1,COG0702@2 NA|NA|NA GM NAD(P)H-binding PGHMIELC_01851 220668.lp_2691 8.2e-96 356.3 Lactobacillaceae wecD Bacteria 1V6Z8@1239,3F6WQ@33958,4HMP7@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) family PGHMIELC_01852 220668.lp_2693 0.0 2402.5 Lactobacillaceae addA 3.6.4.12 ko:K16898 ko00000,ko01000,ko03400 Bacteria 1TQ35@1239,3F3Z0@33958,4HA64@91061,COG1074@1,COG1074@2 NA|NA|NA L ATP-dependent helicase nuclease subunit A PGHMIELC_01853 220668.lp_2694 0.0 2373.6 Lactobacillaceae rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.3,3.6.4.12 ko:K01153,ko:K16899 ko00000,ko01000,ko02048,ko03400 Bacteria 1TQJW@1239,3F3RS@33958,4HAY6@91061,COG3857@1,COG3857@2 NA|NA|NA L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity PGHMIELC_01854 220668.lp_2696 2.9e-171 607.8 Lactobacillaceae ydcZ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 2.A.7.21 Bacteria 1V0FB@1239,3F4R4@33958,4HFG7@91061,COG3238@1,COG3238@2 NA|NA|NA S Putative inner membrane exporter, YdcZ PGHMIELC_01855 220668.lp_2697 1.4e-113 415.6 Lactobacillaceae pyrE 2.4.2.10,4.1.1.23 ko:K00762,ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15560 Bacteria 1V1BZ@1239,3F487@33958,4HFV7@91061,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) PGHMIELC_01856 220668.lp_2698 1.8e-125 455.3 Lactobacillaceae pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750 Bacteria 1TPPH@1239,3F47Y@33958,4HAJ2@91061,COG0284@1,COG0284@2 NA|NA|NA F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) PGHMIELC_01857 220668.lp_2699 9.7e-169 599.4 Lactobacillaceae pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15540 Bacteria 1TPFV@1239,3F4PJ@33958,4HA5H@91061,COG0167@1,COG0167@2 NA|NA|NA F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily PGHMIELC_01858 60520.HR47_14500 0.0 2064.3 Lactobacillaceae carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPID@1239,3F3MD@33958,4HAEY@91061,COG0458@1,COG0458@2 NA|NA|NA F Carbamoyl-phosphate synthase PGHMIELC_01859 220668.lp_2701 1.2e-213 748.8 Lactobacillaceae carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383,iYO844.BSU15510 Bacteria 1TQ8N@1239,3F43R@33958,4H9Z0@91061,COG0505@1,COG0505@2 NA|NA|NA F Carbamoyl-phosphate synthetase glutamine chain PGHMIELC_01860 220668.lp_2702 4.4e-244 850.1 Lactobacillaceae pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPQM@1239,3F3S3@33958,4HA90@91061,COG0044@1,COG0044@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily PGHMIELC_01861 220668.lp_2703 1.1e-172 612.5 Lactobacillaceae pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00608,ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15490 Bacteria 1TQ96@1239,3F4BQ@33958,4H9M6@91061,COG0540@1,COG0540@2 NA|NA|NA F Belongs to the ATCase OTCase family PGHMIELC_01862 1136177.KCA1_2211 1.1e-95 355.9 Lactobacillaceae pyrR GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000,ko03000 iHN637.CLJU_RS05275 Bacteria 1V3GV@1239,3F4SR@33958,4HGYE@91061,COG2065@1,COG2065@2 NA|NA|NA F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant PGHMIELC_01863 220668.lp_2708 1e-298 1031.9 Lactobacillaceae pucR ko:K09684 ko00000,ko03000 Bacteria 1TRDF@1239,3F5A2@33958,4H9KC@91061,COG2508@1,COG2508@2 NA|NA|NA QT Purine catabolism regulatory protein-like family PGHMIELC_01864 220668.lp_2710 2.7e-236 824.3 Lactobacillaceae pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 ko:K02824,ko:K03458,ko:K16169,ko:K16170 ko00000,ko02000 2.A.40,2.A.40.1.1,2.A.40.1.2,2.A.40.3.1,2.A.40.3.2 iSB619.SA_RS02140 Bacteria 1TNZZ@1239,3F3Y7@33958,4HBAM@91061,COG2233@1,COG2233@2 NA|NA|NA F xanthine permease PGHMIELC_01865 220668.lp_2712 2.4e-221 774.6 Lactobacillaceae pbuG ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 1TQC6@1239,3F4QP@33958,4HANG@91061,COG2252@1,COG2252@2 NA|NA|NA S Permease family PGHMIELC_01866 220668.lp_2713 5.6e-161 573.5 Lactobacillaceae Bacteria 1V9EI@1239,3F607@33958,4HJCA@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family PGHMIELC_01867 220668.lp_2714 6.5e-156 556.6 Lactobacillaceae Bacteria 1VM9X@1239,3F5AS@33958,4IF18@91061,COG2200@1,COG2200@2 NA|NA|NA T EAL domain PGHMIELC_01868 220668.lp_2715 4.4e-94 350.5 Lactobacillaceae Bacteria 1VG2N@1239,2E4JE@1,32ZEG@2,3F6QS@33958,4HPPN@91061 NA|NA|NA PGHMIELC_01869 220668.lp_2716 7.8e-252 875.9 Lactobacillaceae pgaC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0007155,GO:0008150,GO:0008194,GO:0008375,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0022610,GO:0031589,GO:0042710,GO:0043708,GO:0044464,GO:0044764,GO:0051704,GO:0071944,GO:0090605 ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.1.1.2,4.D.1.1.3 GT2 Bacteria 1TR2P@1239,3F3RY@33958,4HAQN@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase PGHMIELC_01870 220668.lp_2718 3.9e-127 460.7 Lactobacillaceae 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPDQ@1239,3F6F6@33958,4HADW@91061,COG0620@1,COG0620@2 NA|NA|NA E Methionine synthase PGHMIELC_01871 220668.lp_2719 1.4e-215 755.4 Lactobacillaceae purD 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS05245,iYO844.BSU06530 Bacteria 1UHN9@1239,3F4Z8@33958,4HA70@91061,COG0151@1,COG0151@2 NA|NA|NA F Belongs to the GARS family PGHMIELC_01872 220668.lp_2720 2.7e-288 997.3 Lactobacillaceae purH GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.purH Bacteria 1TPQ5@1239,3F4FD@33958,4H9YY@91061,COG0138@1,COG0138@2 NA|NA|NA F Bifunctional purine biosynthesis protein PurH PGHMIELC_01873 220668.lp_2721 9.9e-103 379.4 Lactobacillaceae purN 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3RJ@1239,3F3UN@33958,4HGY5@91061,COG0299@1,COG0299@2 NA|NA|NA F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate PGHMIELC_01874 220668.lp_2722 7.7e-191 672.9 Lactobacillaceae purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 ko:K01933,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1844,iECSF_1327.ECSF_2340 Bacteria 1TP9J@1239,3F4RT@33958,4HABW@91061,COG0150@1,COG0150@2 NA|NA|NA F Phosphoribosylformylglycinamidine cyclo-ligase PGHMIELC_01875 220668.lp_2723 1.1e-280 971.8 Lactobacillaceae purF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 iSB619.SA_RS05225 Bacteria 1TPH3@1239,3F3U7@33958,4HAXU@91061,COG0034@1,COG0034@2 NA|NA|NA F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine PGHMIELC_01876 220668.lp_2724 0.0 1474.9 Lactobacillaceae purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAS@1239,3F4IQ@33958,4HB3N@91061,COG0046@1,COG0046@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL PGHMIELC_01877 220668.lp_2725 2.2e-125 454.9 Lactobacillaceae purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1B@1239,3F48D@33958,4HAKZ@91061,COG0047@1,COG0047@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL PGHMIELC_01878 220668.lp_2726 3.6e-41 173.7 Lactobacillaceae purS 6.3.2.6,6.3.5.3 ko:K01923,ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463,R04591 RC00010,RC00064,RC00162,RC01160 ko00000,ko00001,ko00002,ko01000 iYO844.BSU06460 Bacteria 1VEH1@1239,3F81F@33958,4HP0E@91061,COG1828@1,COG1828@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL PGHMIELC_01879 220668.lp_2727 2.9e-131 474.6 Lactobacillaceae purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016881,GO:0044424,GO:0044444,GO:0044464 4.1.1.21,4.3.2.2,6.3.2.6 ko:K01587,ko:K01756,ko:K01923 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04209,R04559,R04591 RC00064,RC00162,RC00379,RC00444,RC00445,RC00590 ko00000,ko00001,ko00002,ko01000 iAF1260.b2476,iB21_1397.B21_02330,iBWG_1329.BWG_2240,iE2348C_1286.E2348C_2713,iEC042_1314.EC042_2677,iEC55989_1330.EC55989_2759,iECABU_c1320.ECABU_c27880,iECBD_1354.ECBD_1213,iECB_1328.ECB_02368,iECDH10B_1368.ECDH10B_2642,iECDH1ME8569_1439.ECDH1ME8569_2402,iECDH1ME8569_1439.EcDH1_1193,iECD_1391.ECD_02368,iECED1_1282.ECED1_2911,iECH74115_1262.ECH74115_3698,iECIAI1_1343.ECIAI1_2527,iECNA114_1301.ECNA114_2561,iECO103_1326.ECO103_2988,iECO111_1330.ECO111_3199,iECO26_1355.ECO26_3522,iECOK1_1307.ECOK1_2784,iECP_1309.ECP_2490,iECS88_1305.ECS88_2658,iECSE_1348.ECSE_2760,iECSF_1327.ECSF_2329,iECSP_1301.ECSP_3415,iECUMN_1333.ECUMN_2789,iECW_1372.ECW_m2698,iECs_1301.ECs3338,iEKO11_1354.EKO11_1259,iETEC_1333.ETEC_2581,iEcDH1_1363.EcDH1_1193,iEcE24377_1341.EcE24377A_2757,iEcHS_1320.EcHS_A2607,iEcSMS35_1347.EcSMS35_2623,iEcolC_1368.EcolC_1200,iG2583_1286.G2583_2999,iJN746.PP_1240,iJO1366.b2476,iJR904.b2476,iLF82_1304.LF82_1775,iNRG857_1313.NRG857_12360,iSFV_1184.SFV_2521,iSF_1195.SF2519,iSFxv_1172.SFxv_2773,iS_1188.S2669,iSbBS512_1146.SbBS512_E2848,iUMNK88_1353.UMNK88_3071,iWFL_1372.ECW_m2698,iY75_1357.Y75_RS12925,iYL1228.KPN_02810,iZ_1308.Z3735 Bacteria 1TP11@1239,3F44Z@33958,4H9U8@91061,COG0152@1,COG0152@2 NA|NA|NA F Belongs to the SAICAR synthetase family PGHMIELC_01880 220668.lp_2728 3.9e-212 743.8 Lactobacillaceae purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQCD@1239,3F3YV@33958,4H9M5@91061,COG0026@1,COG0026@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) PGHMIELC_01881 220668.lp_2729 1.7e-79 302.0 Lactobacillaceae purE GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551 Bacteria 1V1MV@1239,3F6P0@33958,4HFR7@91061,COG0041@1,COG0041@2 NA|NA|NA F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) PGHMIELC_01882 220668.lp_2732 1.5e-223 781.9 Lactobacillaceae XK27_09615 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPRA@1239,3F44U@33958,4HDA5@91061,COG0431@1,COG0431@2,COG2461@1,COG2461@2 NA|NA|NA S reductase PGHMIELC_01883 220668.lp_2733 1.8e-110 405.2 Lactobacillaceae XK27_09620 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 1TT2S@1239,3F544@33958,4HBQI@91061,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase PGHMIELC_01884 220668.lp_2734 1.9e-189 668.3 Lactobacillaceae lplA2 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 Bacteria 1TQ5U@1239,3F49I@33958,4H9P6@91061,COG0095@1,COG0095@2 NA|NA|NA H Bacterial lipoate protein ligase C-terminus PGHMIELC_01885 220668.lp_2735 1.4e-147 528.9 Lactobacillaceae ptp3 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1VBGE@1239,3FBJY@33958,4HN6J@91061,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family PGHMIELC_01886 220668.lp_2736 1.9e-118 431.8 Lactobacillaceae cah 4.2.1.1 ko:K01674 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 Bacteria 1V16J@1239,3F7DZ@33958,4HA62@91061,COG3338@1,COG3338@2 NA|NA|NA P Eukaryotic-type carbonic anhydrase PGHMIELC_01887 220668.lp_2737 7.5e-149 533.1 Lactobacillaceae Bacteria 1U5EG@1239,3F5R2@33958,4IF5Z@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF915) PGHMIELC_01888 220668.lp_2738 1.5e-180 638.6 Lactobacillaceae ansA 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 R00485 RC00010,RC02798 ko00000,ko00001,ko01000 Bacteria 1TPP9@1239,3F3XA@33958,4H9YJ@91061,COG0252@1,COG0252@2 NA|NA|NA EJ Asparaginase PGHMIELC_01889 220668.lp_2739 1.7e-139 501.9 Lactobacillaceae cysA ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TNZG@1239,3F3MG@33958,4H9UT@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein PGHMIELC_01890 220668.lp_2740 0.0 1084.3 Lactobacillaceae ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TR2D@1239,3F45H@33958,4HAZG@91061,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family PGHMIELC_01891 220668.lp_2741 8e-42 176.0 Lactobacillaceae Bacteria 1U68A@1239,29P7J@1,30A5N@2,3F7AC@33958,4IFZ1@91061 NA|NA|NA PGHMIELC_01892 220668.lp_2742 7.9e-61 239.6 Lactobacillaceae gntR1 ko:K07979 ko00000,ko03000 Bacteria 1VAC6@1239,3F721@33958,4HKVW@91061,COG1725@1,COG1725@2 NA|NA|NA K Transcriptional regulator, GntR family PGHMIELC_01893 220668.lp_2743 6.9e-164 583.2 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TS5Y@1239,3F4BF@33958,4HBUA@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter, ATP-binding protein PGHMIELC_01894 220668.lp_2744 5.8e-149 533.5 Lactobacillaceae Bacteria 1W561@1239,28V9H@1,2ZHCF@2,3F5C3@33958,4I11A@91061 NA|NA|NA PGHMIELC_01895 220668.lp_2745 6.7e-81 306.6 Lactobacillaceae uspA ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1VEJR@1239,3F4Z0@33958,4HNHG@91061,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein PGHMIELC_01896 220668.lp_2746 1.2e-35 155.2 Lactobacillaceae Bacteria 1U74P@1239,29PWF@1,30AUT@2,3F8Z0@33958,4IGZB@91061 NA|NA|NA PGHMIELC_01897 220668.lp_2747 4.2e-71 273.9 Lactobacillaceae gtcA GO:0000166,GO:0003674,GO:0003824,GO:0003870,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009987,GO:0016020,GO:0016410,GO:0016491,GO:0016620,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0016903,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 Bacteria 1VESW@1239,3F4GH@33958,4HNK7@91061,COG2246@1,COG2246@2 NA|NA|NA S Teichoic acid glycosylation protein PGHMIELC_01898 220668.lp_2748 1.1e-88 332.4 Lactobacillaceae Bacteria 1U5RY@1239,29NX0@1,309V4@2,3F6ER@33958,4IFG8@91061 NA|NA|NA PGHMIELC_01899 220668.lp_2749 9.4e-50 202.6 Lactobacillaceae Bacteria 1U6BS@1239,29PAA@1,30A8F@2,3F7J6@33958,4IG3D@91061 NA|NA|NA PGHMIELC_01901 220668.lp_2751 3.3e-233 813.9 Lactobacillaceae malY 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 Bacteria 1TP5G@1239,3F4JX@33958,4H9PE@91061,COG1168@1,COG1168@2 NA|NA|NA E Aminotransferase, class I PGHMIELC_01902 220668.lp_2753 7.3e-86 323.2 Lactobacillaceae 2.7.7.1,3.6.1.55 ko:K03574,ko:K13522 ko00760,ko01100,map00760,map01100 R00137,R03005 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 1UFAQ@1239,3F648@33958,4IFAZ@91061,COG1051@1,COG1051@2 NA|NA|NA F belongs to the nudix hydrolase family PGHMIELC_01903 220668.lp_2754 5.4e-118 430.3 Lactobacillaceae Bacteria 1U55V@1239,29DQI@1,300NC@2,3F4UQ@33958,4IEX6@91061 NA|NA|NA PGHMIELC_01904 220668.lp_2755 1.5e-52 211.8 Lactobacillaceae Bacteria 1VPSM@1239,2EU16@1,33MI8@2,3F6QA@33958,4HS7T@91061 NA|NA|NA PGHMIELC_01906 220668.lp_2757 0.0 1198.7 Lactobacillaceae nplT 3.2.1.133,3.2.1.135,3.2.1.54 ko:K01208 ko00500,ko01100,map00500,map01100 R02112,R03122,R11262 ko00000,ko00001,ko01000 GH13 Bacteria 1TNZ0@1239,3F41N@33958,4HB67@91061,COG0366@1,COG0366@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family PGHMIELC_01907 220668.lp_2758 3.6e-282 976.9 Lactobacillaceae thrC 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS16355,iIT341.HP0098 Bacteria 1TPR0@1239,3F3UF@33958,4H9R7@91061,COG0498@1,COG0498@2 NA|NA|NA E Threonine synthase PGHMIELC_01908 220668.lp_2759 4.5e-146 523.9 Lactobacillaceae XK27_02985 Bacteria 1TR2E@1239,3F4G9@33958,4HCEA@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase PGHMIELC_01909 220668.lp_2760 5.8e-11 74.7 Lactobacillaceae mcbG Bacteria 1VAPB@1239,3FBAQ@33958,4HH43@91061,COG1357@1,COG1357@2 NA|NA|NA S Pentapeptide repeats (8 copies) PGHMIELC_01910 220668.lp_2761 1.7e-111 408.7 Lactobacillaceae maa 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 ko00000,ko01000 Bacteria 1TQEX@1239,3F59K@33958,4HAJ0@91061,COG0110@1,COG0110@2 NA|NA|NA S Maltose acetyltransferase PGHMIELC_01911 220668.lp_2762 1.7e-102 378.6 Lactobacillaceae 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 Bacteria 1VXC7@1239,3F45R@33958,4HX58@91061,COG0494@1,COG0494@2 NA|NA|NA L Belongs to the Nudix hydrolase family PGHMIELC_01912 220668.lp_2763 7.8e-69 266.2 Lactobacillaceae Bacteria 1VB6J@1239,3F6W7@33958,4HN1R@91061,COG0537@1,COG0537@2 NA|NA|NA FG Scavenger mRNA decapping enzyme C-term binding PGHMIELC_01913 220668.lp_2764 7.5e-135 486.5 Lactobacillaceae Bacteria 1U8IC@1239,3F4X3@33958,4HC26@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase PGHMIELC_01914 220668.lp_2765 1.8e-36 157.9 Lactobacillaceae XK27_01315 Bacteria 1VFBF@1239,2E68Y@1,330X0@2,3F810@33958,4HP3V@91061 NA|NA|NA S Protein of unknown function (DUF2829) PGHMIELC_01915 220668.lp_2766 1.9e-211 741.5 Lactobacillaceae ko:K09963 ko00000 Bacteria 1TRIY@1239,3F4FK@33958,4H9V2@91061,COG3589@1,COG3589@2 NA|NA|NA S Bacterial protein of unknown function (DUF871) PGHMIELC_01916 220668.lp_2767 2.1e-232 811.2 Lactobacillaceae Bacteria 1TRPM@1239,3F5HJ@33958,4HD22@91061,COG4552@1,COG4552@2 NA|NA|NA S Sterol carrier protein domain PGHMIELC_01917 220668.lp_2768 5.2e-224 783.5 Lactobacillaceae Bacteria 1TRZB@1239,3F4VZ@33958,4HC28@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_01918 220668.lp_2770 2.1e-88 331.6 Lactobacillaceae niaR ko:K07105 ko00000 Bacteria 1V6EY@1239,3F7V1@33958,4HGYB@91061,COG1827@1,COG1827@2 NA|NA|NA S 3H domain PGHMIELC_01919 220668.lp_2771 2.3e-265 921.0 Lactobacillaceae pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 Bacteria 1TPDW@1239,3F3K7@33958,4HAI4@91061,COG1488@1,COG1488@2 NA|NA|NA F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP PGHMIELC_01920 220668.lp_2774 8.2e-134 483.0 Lactobacillaceae ko:K01990,ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQKM@1239,3F3VV@33958,4HBUK@91061,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system PGHMIELC_01921 220668.lp_2776 1.1e-245 855.5 Lactobacillaceae dsdA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008721,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009636,GO:0009987,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016840,GO:0016841,GO:0017144,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0033554,GO:0036088,GO:0036094,GO:0042221,GO:0042737,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046416,GO:0048037,GO:0050662,GO:0050896,GO:0051410,GO:0051716,GO:0070178,GO:0070279,GO:0071704,GO:0097159,GO:0098754,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698 4.3.1.18 ko:K01753 ko00260,map00260 R00221 RC02600 ko00000,ko00001,ko01000 iECED1_1282.ECED1_2813,iLF82_1304.LF82_0525,iNRG857_1313.NRG857_11890 Bacteria 1TPAH@1239,3F4S1@33958,4HANC@91061,COG3048@1,COG3048@2 NA|NA|NA E Belongs to the serine threonine dehydratase family. DsdA subfamily PGHMIELC_01922 220668.lp_2777 5.2e-294 1016.1 Lactobacillaceae celA 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family PGHMIELC_01923 220668.lp_2778 3.3e-296 1023.5 Lactobacillaceae celA 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family PGHMIELC_01924 1136177.KCA1_2274 1.8e-54 218.4 Lactobacillaceae chbA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0009987,GO:0015144,GO:0016043,GO:0016740,GO:0016772,GO:0016773,GO:0022607,GO:0022804,GO:0022857,GO:0034219,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0071702,GO:0071840,GO:0090563,GO:0090566,GO:1901264,GO:1902815 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 iECABU_c1320.ECABU_c17610,iECOK1_1307.ECOK1_1683,iECUMN_1333.ECUMN_2025,iNRG857_1313.NRG857_07575,iUMN146_1321.UM146_09345 Bacteria 1VEGE@1239,3F6Z5@33958,4HM37@91061,COG1447@1,COG1447@2 NA|NA|NA G PTS system, Lactose Cellobiose specific IIA subunit PGHMIELC_01925 1136177.KCA1_2275 2.3e-48 198.0 Lactobacillaceae pts20B 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 Bacteria 1VADE@1239,3F6GU@33958,4HKG9@91061,COG1440@1,COG1440@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit PGHMIELC_01926 220668.lp_2782 2e-129 468.4 Lactobacillaceae gntR GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 ko:K03489 ko00000,ko03000 Bacteria 1V54P@1239,3F5X0@33958,4IPPI@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA PGHMIELC_01927 220668.lp_2783 6.8e-141 506.5 Lactobacillaceae epsV 2.7.8.12 ko:K09809 ko00000,ko01000 Bacteria 1VATJ@1239,3F52I@33958,4HNAP@91061,COG1216@1,COG1216@2 NA|NA|NA S glycosyl transferase family 2 PGHMIELC_01928 220668.lp_2785 6.5e-122 443.4 Lactobacillaceae pgm7 5.4.2.11,5.4.2.12 ko:K01834,ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1VDCB@1239,3F50R@33958,4HD4C@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family PGHMIELC_01929 220668.lp_2786 1.8e-81 308.5 Lactobacillaceae Bacteria 1U5R2@1239,2CG6V@1,309UJ@2,3F6C5@33958,4IFF2@91061 NA|NA|NA PGHMIELC_01930 220668.lp_2787 9.8e-152 542.7 Lactobacillaceae Bacteria 1V8IN@1239,3F5CU@33958,4HJUX@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase PGHMIELC_01931 220668.lp_2788 6.5e-182 643.3 Lactobacillaceae panE 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSZ1@1239,3F455@33958,4HB4T@91061,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid PGHMIELC_01932 220668.lp_2789 1.2e-150 539.3 Lactobacillaceae Bacteria 1TR6G@1239,3F423@33958,4HAMD@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family PGHMIELC_01933 220668.lp_2790 1.3e-176 625.5 Lactobacillaceae pdxB 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TSDK@1239,3F4DF@33958,4HAW5@91061,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PGHMIELC_01934 220668.lp_2792 1.2e-100 372.5 Lactobacillaceae 1.5.1.40 ko:K06988 ko00000,ko01000 Bacteria 1V35D@1239,3F5EP@33958,4HFSW@91061,COG2085@1,COG2085@2 NA|NA|NA S NADP oxidoreductase coenzyme F420-dependent PGHMIELC_01935 220668.lp_2793 4.5e-233 814.3 Lactobacillaceae ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1W3NA@1239,28UXD@1,2ZH17@2,3F5J6@33958,4HZFV@91061 NA|NA|NA PGHMIELC_01936 220668.lp_2794 1.5e-77 295.4 Lactobacillaceae fld ko:K03839 ko00000 Bacteria 1V7AG@1239,3F6HY@33958,4HMJF@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin PGHMIELC_01937 220668.lp_2795 0.0 1526.9 Lactobacillaceae ko:K15125 ko05133,map05133 ko00000,ko00001,ko00536 Bacteria 1TT3P@1239,3F4YY@33958,4I28K@91061,COG3209@1,COG3209@2,COG4886@1,COG4886@2 NA|NA|NA M Bacterial Ig-like domain (group 3) PGHMIELC_01938 220668.lp_2795 1.1e-58 232.6 Lactobacillaceae ko:K15125 ko05133,map05133 ko00000,ko00001,ko00536 Bacteria 1TT3P@1239,3F4YY@33958,4I28K@91061,COG3209@1,COG3209@2,COG4886@1,COG4886@2 NA|NA|NA M Bacterial Ig-like domain (group 3) PGHMIELC_01939 220668.lp_2796 0.0 1501.1 Lactobacillaceae ko:K08086,ko:K14195,ko:K15125,ko:K20276 ko02024,ko05133,ko05150,map02024,map05133,map05150 ko00000,ko00001,ko00536 Bacteria 1UYD7@1239,3F7RJ@33958,4HJI6@91061,COG3087@1,COG3087@2,COG3209@1,COG3209@2,COG4886@1,COG4886@2 NA|NA|NA M Bacterial surface protein 26-residue PARCEL repeat (3 repeats) PGHMIELC_01940 220668.lp_2797 2.7e-32 144.1 Lactobacillaceae Bacteria 1U6HE@1239,29PEY@1,30AD4@2,3F7XG@33958,4IG9R@91061 NA|NA|NA PGHMIELC_01941 220668.lp_2798 3.5e-127 461.1 Lactobacillaceae aroD GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.1.25,4.2.1.10 ko:K03785,ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413,R03084 RC00206,RC00848 ko00000,ko00001,ko00002,ko01000 Bacteria 1UUXC@1239,3F5GT@33958,4IF2Z@91061,COG0710@1,COG0710@2 NA|NA|NA E Type I 3-dehydroquinase PGHMIELC_01942 220668.lp_2799 2.2e-268 931.0 Lactobacillaceae ycaM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1TRFS@1239,3FCAH@33958,4HBIP@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid PGHMIELC_01943 220668.lp_2800 3.9e-78 297.4 Lactobacillaceae Bacteria 1U5TQ@1239,3F6HN@33958,4IFHR@91061,COG1846@1,COG1846@2 NA|NA|NA K Winged helix DNA-binding domain PGHMIELC_01944 220668.lp_2802 7.3e-166 589.7 Lactobacillaceae Bacteria 1TPM1@1239,3F4IP@33958,4H9XJ@91061,COG0656@1,COG0656@2 NA|NA|NA S Oxidoreductase, aldo keto reductase family protein PGHMIELC_01945 220668.lp_2803 5.7e-163 580.1 Lactobacillaceae akr5f 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 1TPM1@1239,3FB4Q@33958,4H9XJ@91061,COG0656@1,COG0656@2 NA|NA|NA S reductase PGHMIELC_01946 220668.lp_2804 4.6e-163 580.5 Lactobacillaceae ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1UZXK@1239,3F41Q@33958,4HUWT@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator PGHMIELC_01948 1423758.BN55_02010 1.4e-27 128.6 Lactobacillaceae Bacteria 1V773@1239,3F3JQ@33958,4HIJG@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain protein PGHMIELC_01949 220668.lp_2806 1.8e-84 318.5 Lactobacillaceae hmpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1VBBN@1239,3FBKC@33958,4HMK4@91061,COG4720@1,COG4720@2 NA|NA|NA S Pfam:DUF3816 PGHMIELC_01950 220668.lp_2807 1.5e-241 841.6 Lactobacillaceae tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iAF1260.b1637,iBWG_1329.BWG_1452,iECDH10B_1368.ECDH10B_1771,iECDH1ME8569_1439.ECDH1ME8569_1581,iECH74115_1262.ECH74115_2349,iECIAI39_1322.ECIAI39_1418,iECNA114_1301.ECNA114_1685,iECO103_1326.ECO103_1778,iECO111_1330.ECO111_2107,iECO26_1355.ECO26_2366,iECSE_1348.ECSE_1760,iECSF_1327.ECSF_1500,iECSP_1301.ECSP_2202,iECUMN_1333.ECUMN_1928,iECW_1372.ECW_m1805,iECs_1301.ECs2346,iEKO11_1354.EKO11_2137,iETEC_1333.ETEC_1672,iEcDH1_1363.EcDH1_2003,iEcE24377_1341.EcE24377A_1847,iEcHS_1320.EcHS_A1713,iEcSMS35_1347.EcSMS35_1562,iEcolC_1368.EcolC_1992,iJO1366.b1637,iSFV_1184.SFV_1654,iSF_1195.SF1662,iSSON_1240.SSON_1519,iSbBS512_1146.SbBS512_E1829,iUMNK88_1353.UMNK88_2097,iWFL_1372.ECW_m1805,iY75_1357.Y75_RS08585 Bacteria 1TPGN@1239,3F48J@33958,4H9YV@91061,COG0162@1,COG0162@2 NA|NA|NA J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) PGHMIELC_01951 220668.lp_2809 1e-111 409.5 Lactobacillaceae Bacteria 1U5QM@1239,2A1CJ@1,30PJI@2,3F6BE@33958,4IFEQ@91061 NA|NA|NA PGHMIELC_01952 220668.lp_2810 1.8e-160 572.4 Lactobacillaceae ko:K07273 ko00000 Bacteria 1V2YH@1239,3F6FG@33958,4HKBF@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 PGHMIELC_01953 220668.lp_2812 5.9e-143 513.5 Lactobacillaceae yvpB Bacteria 1V3XE@1239,3F4HZ@33958,4HJBT@91061,COG4990@1,COG4990@2 NA|NA|NA S Peptidase_C39 like family PGHMIELC_01954 220668.lp_2813 1.1e-92 345.9 Lactobacillaceae yueI Bacteria 1U595@1239,3F58I@33958,4IF0H@91061,COG5506@1,COG5506@2 NA|NA|NA S Protein of unknown function (DUF1694) PGHMIELC_01955 220668.lp_2816 1.6e-115 422.2 Lactobacillaceae ko:K07150 ko00000 Bacteria 1U5PM@1239,3FB60@33958,4HAQH@91061,COG1811@1,COG1811@2 NA|NA|NA S Protein of unknown function (DUF554) PGHMIELC_01956 220668.lp_2817 6.4e-148 530.0 Bacilli Bacteria 1V0RM@1239,4IPXS@91061,COG0789@1,COG0789@2 NA|NA|NA KT helix_turn_helix, mercury resistance PGHMIELC_01957 220668.lp_2818 1.7e-227 795.0 Lactobacillaceae gltP GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0008150,GO:0015711,GO:0015849,GO:0016020,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0071702,GO:0071944 ko:K03309,ko:K11102 ko00000,ko02000 2.A.23,2.A.23.1.1,2.A.23.1.2 iPC815.YPO0254,iYO844.BSU10220 Bacteria 1TPME@1239,3F4Q2@33958,4H9T7@91061,COG1301@1,COG1301@2 NA|NA|NA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family PGHMIELC_01958 220668.lp_2820 6.6e-95 353.2 Lactobacillaceae ko:K08996 ko00000 Bacteria 1VX0K@1239,3F6A5@33958,4HX2R@91061,COG3477@1,COG3477@2 NA|NA|NA S Protein of unknown function (DUF1440) PGHMIELC_01959 220668.lp_2822 2.9e-172 611.3 Lactobacillaceae hrtB ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TWFZ@1239,3F3K5@33958,4H9RQ@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease PGHMIELC_01960 220668.lp_2823 5.6e-121 440.3 Lactobacillaceae devA 3.6.3.25 ko:K02003,ko:K06020,ko:K09810 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 Bacteria 1TQP5@1239,3F4RP@33958,4HBXK@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein PGHMIELC_01961 220668.lp_2824 1.4e-90 339.0 Lactobacillaceae 2.7.7.65 ko:K16923,ko:K18967 M00582 ko00000,ko00002,ko01000,ko02000 3.A.1.28,9.B.34.1.1 Bacteria 1UZUT@1239,3F4G1@33958,4HMC0@91061,COG3275@1,COG3275@2 NA|NA|NA T phosphorelay sensor kinase activity PGHMIELC_01962 220668.lp_2825 4.2e-186 657.1 Lactobacillaceae iunH 3.2.2.1 ko:K01239,ko:K01250 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 Bacteria 1TRQQ@1239,3F4ZB@33958,4IQRZ@91061,COG1957@1,COG1957@2 NA|NA|NA F Inosine-uridine preferring nucleoside hydrolase PGHMIELC_01963 220668.lp_2826 1.1e-98 365.9 Lactobacillaceae 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 Bacteria 1VAUA@1239,3F57D@33958,4HH71@91061,COG0262@1,COG0262@2 NA|NA|NA H RibD C-terminal domain PGHMIELC_01964 220668.lp_2827 1.5e-187 662.1 Lactobacillaceae napA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 Bacteria 1TS32@1239,3F3QK@33958,4HAGC@91061,COG0475@1,COG0475@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family PGHMIELC_01965 60520.HR47_02060 7.5e-110 403.3 Lactobacillaceae Bacteria 1V8E3@1239,3F4H9@33958,4HJ08@91061,COG2364@1,COG2364@2 NA|NA|NA S Membrane PGHMIELC_01966 220668.lp_2829 1.2e-155 555.8 Lactobacillaceae mleP3 ko:K07088 ko00000 Bacteria 1V0E3@1239,3F4BN@33958,4IQTM@91061,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein PGHMIELC_01967 220668.lp_2830 3.4e-258 897.1 Lactobacillaceae aspA 4.2.1.2,4.3.1.1 ko:K01679,ko:K01744 ko00020,ko00250,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00250,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R00490,R01082 RC00316,RC00443,RC02799 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP3U@1239,3FBTC@33958,4HFM9@91061,COG1027@1,COG1027@2 NA|NA|NA E Fumarase C C-terminus PGHMIELC_01968 220668.lp_2833 4.9e-189 667.2 Lactobacillaceae ynfM Bacteria 1TS0E@1239,3F5GE@33958,4HCEF@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_01969 220668.lp_2835 2.8e-125 454.5 Lactobacillaceae hadL 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 R05287 RC00697 ko00000,ko00001,ko01000 Bacteria 1TQYM@1239,3F7UN@33958,4HPIM@91061,COG1011@1,COG1011@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase PGHMIELC_01970 220668.lp_2836 1.1e-270 938.7 Lactobacillaceae lmrB Bacteria 1TPRN@1239,3F4A2@33958,4H9VV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_01971 220668.lp_2839 2e-75 288.5 Lactobacillaceae Bacteria 1U5T4@1239,2C9UQ@1,309VR@2,3F6FU@33958,4IFH1@91061 NA|NA|NA S Domain of unknown function (DUF4811) PGHMIELC_01972 220668.lp_2840 4e-99 367.5 Lactobacillaceae rimL ko:K03817 ko00000,ko01000,ko03009 Bacteria 1V3NE@1239,3F6YW@33958,4HG1N@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain PGHMIELC_01973 220668.lp_2841 1.2e-172 612.5 Lactobacillaceae Bacteria 1TQYA@1239,3F4TY@33958,4HCCP@91061,COG2855@1,COG2855@2 NA|NA|NA S Conserved hypothetical protein 698 PGHMIELC_01974 220668.lp_2842 3.7e-151 540.8 Lactobacillaceae rlrG ko:K21900 ko00000,ko03000 Bacteria 1TP6T@1239,3F4VC@33958,4HC4T@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator PGHMIELC_01975 220668.lp_2843 1.2e-296 1025.0 Lactobacillaceae tagE5 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1VSNK@1239,3F4VP@33958,4HU8G@91061,COG0438@1,COG0438@2 NA|NA|NA M Poly(Glycerol-phosphate) alpha-glucosyltransferase PGHMIELC_01976 220668.lp_2844 6.9e-268 929.5 Lactobacillaceae tagE6 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1V09I@1239,3FBDH@33958,4HDDD@91061,COG0438@1,COG0438@2,COG2849@1,COG2849@2 NA|NA|NA M Glycosyl transferases group 1 PGHMIELC_01977 220668.342242703 1.6e-33 150.2 Lactobacillaceae lytE Bacteria 1V773@1239,3F3JQ@33958,4HIJG@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain protein PGHMIELC_01978 220668.lp_2847 7e-54 218.0 Lactobacillaceae lytE Bacteria 1U5BF@1239,3F5FT@33958,4IF2S@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain PGHMIELC_01979 220668.lp_2848 1.8e-92 345.1 Lactobacillaceae ogt 2.1.1.63 ko:K00567,ko:K10778,ko:K13531 ko00000,ko01000,ko03000,ko03400 Bacteria 1VA03@1239,3F6RF@33958,4HETA@91061,COG0350@1,COG0350@2 NA|NA|NA L Methyltransferase PGHMIELC_01980 220668.lp_2849 3.6e-168 597.4 Lactobacillaceae natA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TR06@1239,3F4J8@33958,4H9RX@91061,COG4152@1,COG4152@2 NA|NA|NA S ABC transporter, ATP-binding protein PGHMIELC_01981 220668.lp_2850 1.2e-211 742.3 Lactobacillaceae natB ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TXRK@1239,3F3KA@33958,4HC9K@91061,COG1668@1,COG1668@2 NA|NA|NA CP ABC-2 family transporter protein PGHMIELC_01982 220668.lp_2851 1e-128 466.1 Lactobacillaceae Bacteria 1TRHF@1239,3F3VA@33958,4HBXH@91061,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family PGHMIELC_01983 220668.lp_2852 6.6e-56 223.0 Lactobacillaceae yphJ 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R03470 RC00938 ko00000,ko00001,ko01000 Bacteria 1V5CC@1239,3FBIG@33958,4HXN0@91061,COG0599@1,COG0599@2 NA|NA|NA S Carboxymuconolactone decarboxylase family PGHMIELC_01984 220668.lp_2853 3.2e-76 290.8 Lactobacillaceae yphH Bacteria 1V3TP@1239,3FBIH@33958,4HWR6@91061,COG1917@1,COG1917@2 NA|NA|NA S Cupin domain PGHMIELC_01985 220668.lp_2854 4.4e-79 300.4 Lactobacillaceae Bacteria 1VAT0@1239,3FC64@33958,4HKQ1@91061,COG0789@1,COG0789@2 NA|NA|NA K transcriptional regulator, MerR family PGHMIELC_01986 220668.lp_2855 2.3e-237 827.8 Lactobacillaceae dapE 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMJ@1239,3F3N9@33958,4HB39@91061,COG0624@1,COG0624@2 NA|NA|NA E succinyl-diaminopimelate desuccinylase PGHMIELC_01987 220668.lp_2856 0.0 1584.7 Lactobacillaceae ylbB ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPHU@1239,3F4HF@33958,4HA2C@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease PGHMIELC_01988 60520.HR47_02180 3.7e-120 437.6 Lactobacillaceae macB ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQC9@1239,3F3YU@33958,4HB8D@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein PGHMIELC_01990 60520.HR47_02190 8e-117 426.4 Lactobacillaceae nth 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TRAK@1239,3F42U@33958,4HATD@91061,COG0177@1,COG0177@2 NA|NA|NA L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate PGHMIELC_01991 220668.lp_2861 2.2e-100 371.7 Lactobacillaceae maa 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 ko00000,ko01000 Bacteria 1TQEX@1239,3FBEM@33958,4HGH2@91061,COG0110@1,COG0110@2 NA|NA|NA S Maltose acetyltransferase PGHMIELC_01992 220668.lp_2862 8.4e-116 422.9 Lactobacillaceae lepB 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1V7H9@1239,3F56W@33958,4HMGQ@91061,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family PGHMIELC_01993 220668.lp_2864 2.4e-83 314.7 Lactobacillaceae Bacteria 1U5T3@1239,29NXJ@1,309VP@2,3F6FR@33958,4IFH0@91061 NA|NA|NA PGHMIELC_01994 220668.lp_2865 1.6e-85 322.0 Lactobacillaceae yvbK 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3IC@1239,3F7GI@33958,4HH45@91061,COG0454@1,COG0456@2 NA|NA|NA K GNAT family PGHMIELC_01995 220668.lp_2866 7e-37 159.5 Lactobacillaceae Bacteria 1U6B1@1239,29P9Q@1,30A7U@2,3F7HP@33958,4IG2I@91061 NA|NA|NA PGHMIELC_01996 220668.lp_2867 8.2e-48 196.1 Lactobacillaceae Bacteria 1U65K@1239,29P5Q@1,30A3V@2,3F748@33958,4IFVF@91061 NA|NA|NA PGHMIELC_01997 220668.lp_2868 1.2e-112 412.5 Lactobacillaceae pgm8 Bacteria 1UUX3@1239,3F5PY@33958,4I2XG@91061,COG0406@1,COG0406@2 NA|NA|NA G Histidine phosphatase superfamily (branch 1) PGHMIELC_01998 220668.lp_2870 8.4e-60 236.1 Lactobacillaceae Bacteria 1V42S@1239,291WS@1,2ZPGE@2,3F78I@33958,4ISVW@91061 NA|NA|NA S Domain of unknown function (DUF4440) PGHMIELC_01999 220668.lp_2871 2.8e-157 561.2 Lactobacillaceae Bacteria 1TT5B@1239,3F5CC@33958,4HK1M@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain PGHMIELC_02000 220668.lp_2872 1.2e-103 382.5 Lactobacillaceae Bacteria 1UJSC@1239,3F60E@33958,4HGYK@91061,COG0702@1,COG0702@2 NA|NA|NA GM NAD(P)H-binding PGHMIELC_02001 220668.lp_2873 2.3e-195 688.0 Lactobacillaceae adh 1.1.1.1,1.1.1.14 ko:K00001,ko:K00008 ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 M00014 R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPIW@1239,3F42F@33958,4HB2G@91061,COG1063@1,COG1063@2 NA|NA|NA E alcohol dehydrogenase PGHMIELC_02002 220668.lp_2874 1.4e-150 538.9 Lactobacillaceae Bacteria 1TSJI@1239,3F5I6@33958,4HG70@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase PGHMIELC_02003 60520.HR47_03855 4.7e-141 507.3 Lactobacillaceae aRA11 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 1TPM1@1239,3FB4Q@33958,4H9XJ@91061,COG0656@1,COG0656@2 NA|NA|NA S reductase PGHMIELC_02004 60520.HR47_03850 3.3e-82 311.2 Lactobacillaceae yiiE Bacteria 1V9R0@1239,3FB5Z@33958,4HJB5@91061,COG3548@1,COG3548@2 NA|NA|NA S Protein of unknown function (DUF1211) PGHMIELC_02005 60520.HR47_03830 4.2e-76 291.2 Lactobacillaceae darA Bacteria 1V45R@1239,3F7P2@33958,4HQY8@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin PGHMIELC_02006 278197.PEPE_0073 3e-126 458.0 Lactobacillaceae Bacteria 1TRQC@1239,3F4FH@33958,4HD7P@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase PGHMIELC_02007 585524.HMPREF0493_0922 8.1e-85 320.5 Lactobacillaceae glcU ko:K05340 ko00000,ko02000 2.A.7.5 Bacteria 1TQBN@1239,3F4K2@33958,4HAVH@91061,COG4975@1,COG4975@2 NA|NA|NA U sugar transport PGHMIELC_02008 1071400.LBUCD034_0258 2.5e-86 325.1 Lactobacillaceae Bacteria 1V7A7@1239,3F63T@33958,4HIII@91061,COG0702@1,COG0702@2 NA|NA|NA GM NAD(P)H-binding PGHMIELC_02009 220668.lp_2803 6.4e-109 400.6 Lactobacillaceae akr5f 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 1TPM1@1239,3FB4Q@33958,4H9XJ@91061,COG0656@1,COG0656@2 NA|NA|NA S reductase PGHMIELC_02010 349123.Lreu23DRAFT_4791 2e-78 299.3 Lactobacillaceae ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1UZXK@1239,3F41Q@33958,4HUWT@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator PGHMIELC_02012 1423743.JCM14108_1583 3e-25 121.7 Lactobacillaceae fldA Bacteria 1V23B@1239,3FBBN@33958,4HYW6@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin PGHMIELC_02013 525318.HMPREF0497_2534 4.4e-10 70.5 Lactobacillaceae adhR Bacteria 1VAAP@1239,3F6JI@33958,4HKZ9@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance PGHMIELC_02014 1423815.BACR01000023_gene1229 2.5e-114 418.3 Lactobacillaceae Bacteria 1TRHF@1239,3F3VA@33958,4HBXH@91061,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family PGHMIELC_02015 60520.HR47_03860 1.3e-130 472.6 Lactobacillaceae Bacteria 1TPM1@1239,3F3PW@33958,4HARE@91061,COG0656@1,COG0656@2 NA|NA|NA C Aldo keto reductase PGHMIELC_02016 1423775.BAMN01000005_gene1339 1.5e-142 512.3 Lactobacillaceae akr5f 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 1TPM1@1239,3FB4Q@33958,4H9XJ@91061,COG0656@1,COG0656@2 NA|NA|NA S reductase PGHMIELC_02017 1136177.KCA1_2787 1.3e-142 513.1 Lactobacillaceae Bacteria 1TPHW@1239,3F57A@33958,4HDHP@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Major Facilitator Superfamily PGHMIELC_02018 1071400.LBUCD034_0258 5.7e-83 313.9 Lactobacillaceae Bacteria 1V7A7@1239,3F63T@33958,4HIII@91061,COG0702@1,COG0702@2 NA|NA|NA GM NAD(P)H-binding PGHMIELC_02019 220668.lp_2877 6.1e-76 290.0 Lactobacillaceae Bacteria 1V8UY@1239,3F6N5@33958,4HK2J@91061,COG0589@1,COG0589@2 NA|NA|NA T Belongs to the universal stress protein A family PGHMIELC_02020 220668.lp_2878 5.8e-95 353.6 Lactobacillaceae maa 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 ko00000,ko01000 Bacteria 1TQEX@1239,3F47V@33958,4HAJ0@91061,COG0110@1,COG0110@2 NA|NA|NA S Maltose O-acetyltransferase PGHMIELC_02021 220668.lp_2879 1.9e-124 451.8 Lactobacillaceae yjjG GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006206,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008655,GO:0009058,GO:0009112,GO:0009410,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019856,GO:0019859,GO:0030145,GO:0034641,GO:0034654,GO:0042221,GO:0042578,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.102,3.1.3.104,3.1.3.5,3.8.1.2 ko:K01560,ko:K07025,ko:K08723,ko:K20862 ko00230,ko00240,ko00361,ko00625,ko00740,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00740,map00760,map01100,map01110,map01120 M00125 R00183,R00511,R00548,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287,R07280 RC00017,RC00697 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_4614 Bacteria 1TS3W@1239,3F4NI@33958,4HADE@91061,COG1011@1,COG1011@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase PGHMIELC_02022 220668.lp_2885 1.5e-81 308.9 Lactobacillaceae Bacteria 1U89N@1239,29QKQ@1,30BKC@2,3FAQV@33958,4II7K@91061 NA|NA|NA PGHMIELC_02023 220668.lp_2887 3.9e-102 377.5 Lactobacillaceae 1.5.1.40 ko:K06988 ko00000,ko01000 Bacteria 1VW6H@1239,3F6QU@33958,4HWI6@91061,COG2085@1,COG2085@2 NA|NA|NA S NADP oxidoreductase coenzyme F420-dependent PGHMIELC_02024 220668.lp_2888 5.7e-222 776.5 Lactobacillaceae patB 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 Bacteria 1TP5G@1239,3F4JX@33958,4H9PE@91061,COG1168@1,COG1168@2 NA|NA|NA E Aminotransferase, class I PGHMIELC_02025 220668.lp_2889 9.7e-102 376.7 Lactobacillaceae Bacteria 1TQXN@1239,3F4Y5@33958,4HBHT@91061,COG5434@1,COG5434@2 NA|NA|NA M Protein of unknown function (DUF3737) PGHMIELC_02026 220668.lp_2890 6.3e-193 679.9 Lactobacillaceae Bacteria 1TQJC@1239,3FB4P@33958,4HC0W@91061,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family PGHMIELC_02028 220668.lp_2893 0.0 1151.0 Lactobacillaceae mdlB GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008144,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0033036,GO:0034040,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K06147,ko:K18890 ko02010,map02010 M00707 ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter PGHMIELC_02029 220668.lp_2894 0.0 1094.0 Lactobacillaceae mdlA GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016021,GO:0017076,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K06148,ko:K18889 ko02010,map02010 M00707 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter PGHMIELC_02030 60520.HR47_00050 7.4e-245 852.8 Lactobacillaceae ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1UYQB@1239,3F3NG@33958,4HE3Y@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_02032 1158604.I591_01494 6.4e-08 64.3 Enterococcaceae Bacteria 1U2IZ@1239,2DK07@1,3080H@2,4B4X4@81852,4IC6A@91061 NA|NA|NA PGHMIELC_02033 220668.lp_2901 1e-175 624.4 Lactobacillaceae yhgE ko:K01421 ko00000 Bacteria 1TQ15@1239,3F3Y3@33958,4H9T9@91061,COG1511@1,COG1511@2 NA|NA|NA V domain protein PGHMIELC_02034 220668.lp_2902 1.1e-95 355.9 Lactobacillaceae Bacteria 1VEM5@1239,3F66Z@33958,4HQRV@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator (TetR family) PGHMIELC_02035 220668.lp_2903 1.4e-53 215.3 Lactobacillaceae ko:K03892 ko00000,ko03000 Bacteria 1VFY4@1239,3F6VK@33958,4HP5T@91061,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor PGHMIELC_02036 220668.lp_2906 8.8e-141 506.5 Lactobacillaceae endA ko:K15051 ko00000 Bacteria 1V4X2@1239,3F3Y8@33958,4HIF5@91061,COG2169@1,COG2169@2 NA|NA|NA F DNA RNA non-specific endonuclease PGHMIELC_02037 220668.lp_2907 2.1e-102 378.3 Lactobacillaceae speG ko:K07023 ko00000 Bacteria 1V3W1@1239,3F6G6@33958,4HH6A@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain PGHMIELC_02038 220668.lp_2909 5.7e-97 360.1 Lactobacillaceae 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 1TVME@1239,3F5W5@33958,4I3IH@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain PGHMIELC_02039 220668.lp_2911 1.7e-221 775.0 Lactobacillaceae ko:K07052 ko00000 Bacteria 1VNA9@1239,3F5T9@33958,4HRMP@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity PGHMIELC_02040 220668.lp_2912 3.2e-308 1063.5 Lactobacillaceae ybiT GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896 ko:K06158 ko00000,ko03012 Bacteria 1TPW0@1239,3F3ZJ@33958,4HATH@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein PGHMIELC_02041 220668.lp_2913 2e-146 525.0 Lactobacillaceae 3.1.3.102,3.1.3.104 ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V2JE@1239,3F3Z7@33958,4HWAW@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase PGHMIELC_02042 220668.lp_2914 0.0 1093.2 Lactobacillaceae Bacteria 1TS3Q@1239,3F4AT@33958,4HF7D@91061,COG4907@1,COG4907@2 NA|NA|NA S Predicted membrane protein (DUF2207) PGHMIELC_02043 220668.lp_2915 0.0 1652.5 Lactobacillaceae uvrA3 ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TP0A@1239,3FC8R@33958,4HTKA@91061,COG0178@1,COG0178@2 NA|NA|NA L excinuclease ABC PGHMIELC_02044 220668.lp_2917 1.3e-205 722.2 Lactobacillaceae Bacteria 1UG5D@1239,2ZBIK@2,3FBS8@33958,4H9W5@91061,COG0477@1 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_02045 220668.lp_2918 2.4e-172 611.3 Lactobacillaceae ropB Bacteria 1VHH9@1239,3F4WA@33958,4HHNF@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins PGHMIELC_02046 220668.lp_2921 2.9e-232 810.8 Lactobacillaceae yxiO ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 Bacteria 1TRTH@1239,3F5D5@33958,4H9VB@91061,COG2270@1,COG2270@2 NA|NA|NA S Vacuole effluxer Atg22 like PGHMIELC_02047 220668.lp_2922 4.3e-255 886.7 Lactobacillaceae npp Bacteria 1TRZ7@1239,3F4V5@33958,4HAY5@91061,COG1524@1,COG1524@2 NA|NA|NA S type I phosphodiesterase nucleotide pyrophosphatase PGHMIELC_02048 220668.lp_2923 2.4e-158 564.7 Lactobacillaceae Bacteria 1TP1H@1239,3F43I@33958,4HFZ9@91061,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold PGHMIELC_02049 220668.lp_2924 1.3e-128 465.7 Lactobacillaceae treR ko:K03486,ko:K03492,ko:K03710 ko00000,ko03000 Bacteria 1TRF6@1239,3F5MQ@33958,4HDCX@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA PGHMIELC_02050 220668.lp_2925 1.6e-237 829.3 Lactobacillaceae Bacteria 1VNWP@1239,2DBU6@1,2ZB4C@2,3F51G@33958,4HRN6@91061 NA|NA|NA PGHMIELC_02051 220668.lp_2926 5.6e-39 166.4 Lactobacillaceae Bacteria 1V64Y@1239,3F812@33958,4HNUM@91061,COG4892@1,COG4892@2 NA|NA|NA S Cytochrome B5 PGHMIELC_02052 220668.lp_2927 2.2e-88 331.6 Lactobacillaceae pts21A ko:K02755,ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 Bacteria 1U5RJ@1239,3F6DI@33958,4IFFQ@91061,COG2190@1,COG2190@2 NA|NA|NA G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PGHMIELC_02053 220668.lp_2929 6.2e-218 763.1 Lactobacillaceae 2.7.7.65 ko:K18967 ko00000,ko01000,ko02000 9.B.34.1.1 Bacteria 1UI5F@1239,3F4GZ@33958,4ISED@91061,COG2199@1,COG2199@2 NA|NA|NA T Diguanylate cyclase, GGDEF domain PGHMIELC_02054 220668.lp_2930 3.1e-127 461.1 Lactobacillaceae yliE GO:0003674,GO:0003824,GO:0008081,GO:0016787,GO:0016788,GO:0042578,GO:0071111 Bacteria 1TVGQ@1239,3F626@33958,4HVXY@91061,COG2200@1,COG2200@2 NA|NA|NA T EAL domain PGHMIELC_02055 220668.lp_2931 2.2e-104 384.8 Lactobacillaceae nrdG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0031250,GO:0032991,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 1.97.1.4 ko:K04068 R04710 ko00000,ko01000 iE2348C_1286.E2348C_4563 Bacteria 1V1HG@1239,3F46H@33958,4HGJ9@91061,COG0602@1,COG0602@2 NA|NA|NA O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine PGHMIELC_02056 220668.lp_2932 0.0 1524.2 Lactobacillaceae nrdD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019001,GO:0019103,GO:0019438,GO:0019637,GO:0019692,GO:0030554,GO:0031250,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032556,GO:0032558,GO:0032559,GO:0032560,GO:0032564,GO:0032567,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0046872,GO:0046914,GO:0051065,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_4713,iPC815.YPO3454 Bacteria 1TR9K@1239,3F435@33958,4HBIY@91061,COG1328@1,COG1328@2 NA|NA|NA F Ribonucleoside-triphosphate reductase PGHMIELC_02057 220668.lp_2934 2e-80 305.1 Lactobacillaceae Bacteria 1U68H@1239,2CIIZ@1,30A5S@2,3F7AW@33958,4IFZC@91061 NA|NA|NA PGHMIELC_02058 220668.lp_2935 4.5e-73 280.4 Lactobacillaceae def2 3.5.1.31,3.5.1.88 ko:K01450,ko:K01462 ko00270,ko00630,map00270,map00630 R00653 RC00165,RC00323 ko00000,ko00001,ko01000 Bacteria 1V73T@1239,3F6ZA@33958,4HISW@91061,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins PGHMIELC_02059 220668.lp_2936 5.8e-191 673.3 Lactobacillaceae apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 1TR9C@1239,3FB4A@33958,4HDFE@91061,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein PGHMIELC_02060 220668.lp_2937 7.6e-191 672.9 Lactobacillaceae dus ko:K05541 ko00000,ko01000,ko03016 Bacteria 1TQ2R@1239,3F4D2@33958,4HA9K@91061,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines PGHMIELC_02061 220668.lp_2939 4.9e-22 109.8 Lactobacillaceae Bacteria 1U6VG@1239,29PPJ@1,30AMQ@2,3F8JU@33958,4IGPD@91061 NA|NA|NA PGHMIELC_02062 220668.lp_2940 4.4e-79 302.0 Lactobacillaceae Bacteria 1U5R1@1239,2DKKR@1,309UI@2,3F6C4@33958,4IFF1@91061 NA|NA|NA PGHMIELC_02063 220668.lp_2942 2.2e-165 588.2 Lactobacillaceae ko:K09681 ko00000,ko03000 Bacteria 1TQ6Y@1239,3F4CY@33958,4HWQQ@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain PGHMIELC_02064 220668.lp_2943 2.4e-243 847.8 Lactobacillaceae ko:K03319 ko00000 2.A.47 Bacteria 1V093@1239,3F3VN@33958,4HQP0@91061,COG0471@1,COG0471@2 NA|NA|NA P Sodium:sulfate symporter transmembrane region PGHMIELC_02065 220668.lp_2945 3.7e-287 993.4 Lactobacillaceae ubiD 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ6V@1239,3FB9Z@33958,4HE3C@91061,COG0043@1,COG0043@2 NA|NA|NA H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase PGHMIELC_02066 220668.lp_2948 7.4e-264 916.0 Lactobacillaceae Bacteria 1UYJN@1239,3FBEE@33958,4HF8I@91061,COG4640@1,COG4640@2 NA|NA|NA S response to antibiotic PGHMIELC_02067 220668.lp_2949 1.8e-133 482.3 Lactobacillaceae Bacteria 1VIMB@1239,3F7Z9@33958,4HP7R@91061,COG4640@1,COG4640@2 NA|NA|NA S zinc-ribbon domain PGHMIELC_02069 220668.lp_2952 3.2e-37 160.6 Lactobacillaceae Bacteria 1U6AH@1239,2DKPD@1,30A7H@2,3F7FZ@33958,4IG1V@91061 NA|NA|NA PGHMIELC_02070 220668.lp_2953 8.2e-134 483.0 Lactobacillaceae aroD ko:K06889 ko00000 Bacteria 1V43W@1239,3F4SI@33958,4HNBU@91061,COG1073@1,COG1073@2 NA|NA|NA S Alpha/beta hydrolase family PGHMIELC_02071 220668.lp_2954 5.2e-177 627.1 Lactobacillaceae ko:K07035 ko00000 Bacteria 1TS5F@1239,3F4FE@33958,4HC7U@91061,COG3641@1,COG3641@2 NA|NA|NA S Phosphotransferase system, EIIC PGHMIELC_02072 220668.lp_2956 9.7e-269 932.2 Lactobacillaceae ko:K01066 ko00000,ko01000 Bacteria 1USHI@1239,3F5U2@33958,4ISEE@91061,COG0657@1,COG0657@2 NA|NA|NA I acetylesterase activity PGHMIELC_02073 220668.lp_2958 2.1e-223 781.9 Lactobacillaceae sdrF ko:K14192,ko:K14194,ko:K14201 ko05150,map05150 ko00000,ko00001 Bacteria 1TQBI@1239,3F52Y@33958,4HBAT@91061,COG4932@1,COG4932@2 NA|NA|NA M Collagen binding domain PGHMIELC_02074 220668.lp_2959 1.1e-159 569.3 Lactobacillaceae yicL Bacteria 1TR6G@1239,3F423@33958,4HAMD@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family PGHMIELC_02075 220668.lp_2960 4.4e-129 467.2 Lactobacillaceae Bacteria 1UI5G@1239,3F652@33958,4ISEF@91061,COG2755@1,COG2755@2 NA|NA|NA E lipolytic protein G-D-S-L family PGHMIELC_02076 220668.lp_2961 1.1e-177 629.0 Lactobacillaceae 4.1.1.52 ko:K22213 ko00000,ko01000 Bacteria 1TRAY@1239,3F485@33958,4HFH2@91061,COG2159@1,COG2159@2 NA|NA|NA S Amidohydrolase PGHMIELC_02077 220668.lp_2963 2.1e-111 408.3 Lactobacillaceae Bacteria 1V9XI@1239,3F77G@33958,4HJ7Q@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator C-terminal region PGHMIELC_02078 220668.lp_2964 1.4e-47 195.3 Lactobacillaceae 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1U6V2@1239,3F8J1@33958,4IGNZ@91061,COG1733@1,COG1733@2 NA|NA|NA K HxlR-like helix-turn-helix PGHMIELC_02079 220668.lp_2965 1.2e-160 572.4 Lactobacillaceae ypbG 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1UZ80@1239,3FBD4@33958,4HD5J@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family PGHMIELC_02080 220668.lp_2966 0.0 1112.1 Lactobacillaceae lmrA 3.6.3.44 ko:K06147,ko:K18104 ko01501,ko02010,map01501,map02010 M00700 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 3.A.1.106,3.A.1.109,3.A.1.117,3.A.1.123,3.A.1.21 Bacteria 1TSY4@1239,3FC4S@33958,4HAJQ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter PGHMIELC_02081 60520.HR47_01940 2.9e-96 357.8 Lactobacillaceae rmaB Bacteria 1VF51@1239,3F725@33958,4HM7R@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator, MarR family PGHMIELC_02082 220668.lp_2968 5e-119 433.7 Lactobacillaceae drgA Bacteria 1UYJU@1239,3F4H1@33958,4HBVQ@91061,COG0778@1,COG0778@2 NA|NA|NA C Nitroreductase family PGHMIELC_02083 220668.lp_2969 0.0 1229.2 Lactobacillaceae nagE GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0008643,GO:0009401,GO:0009987,GO:0015144,GO:0015764,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0033554,GO:0034219,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071702,GO:0090563,GO:0090586,GO:1901264 2.7.1.193,2.7.1.199,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K02808,ko:K02809,ko:K02810,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00267,M00268,M00269,M00270,M00271,M00272,M00303,M00806,M00809 R00811,R02738,R02780,R04111,R04394,R05132,R05199,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.13,4.A.1.1.14,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.1.9,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 iECP_1309.ECP_0691,iSB619.SA_RS08720 Bacteria 1TPJ8@1239,3F44V@33958,4HA8X@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system, EIIB PGHMIELC_02084 220668.lp_2972 8.1e-109 399.8 Lactobacillaceae cmpC ko:K05833 M00247 ko00000,ko00002,ko02000 Bacteria 1TPAN@1239,3F55Q@33958,4HCHC@91061,COG1101@1,COG1101@2 NA|NA|NA S ATPases associated with a variety of cellular activities PGHMIELC_02085 220668.lp_2973 8.1e-153 546.6 Lactobacillaceae WQ51_06230 ko:K01989,ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPDJ@1239,3F40J@33958,4HBMY@91061,COG4120@1,COG4120@2 NA|NA|NA U Belongs to the binding-protein-dependent transport system permease family PGHMIELC_02086 220668.lp_2974 3.5e-169 600.9 Lactobacillaceae XK27_00670 ko:K01989,ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPB0@1239,3F462@33958,4HESK@91061,COG2984@1,COG2984@2 NA|NA|NA S ABC transporter PGHMIELC_02087 220668.lp_2975 6.7e-260 902.9 Lactobacillaceae Bacteria 1U7E1@1239,2BHMA@1,32BQ0@2,3F9G7@33958,4IH9X@91061 NA|NA|NA PGHMIELC_02088 220668.lp_2976 8.6e-63 246.1 Lactobacillaceae Bacteria 1U84Z@1239,29QI7@1,30BHP@2,3FAJ6@33958,4II2F@91061 NA|NA|NA PGHMIELC_02089 220668.lp_2977 8.1e-188 662.9 Lactobacillaceae Bacteria 1V92G@1239,3F407@33958,4HIJ2@91061,COG4072@1,COG4072@2 NA|NA|NA S Cell surface protein PGHMIELC_02090 220668.lp_2978 5.1e-91 340.9 Lactobacillaceae Bacteria 1U7D3@1239,29Q2H@1,30B15@2,3F9EG@33958,4IH8P@91061 NA|NA|NA S WxL domain surface cell wall-binding PGHMIELC_02091 60520.HR47_01890 2.4e-97 361.7 Lactobacillaceae acuB ko:K04767 ko00000 Bacteria 1V0XU@1239,3F6J3@33958,4HD12@91061,COG0517@1,COG0517@2 NA|NA|NA S Domain in cystathionine beta-synthase and other proteins. PGHMIELC_02092 220668.lp_2981 9.5e-124 449.5 Lactobacillaceae livF ko:K01996 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 1TPW4@1239,3F3RP@33958,4HABJ@91061,COG0410@1,COG0410@2 NA|NA|NA E ABC transporter PGHMIELC_02093 220668.lp_2982 1.8e-139 501.9 Lactobacillaceae livG ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 1TR0P@1239,3F4IH@33958,4HASG@91061,COG0411@1,COG0411@2 NA|NA|NA E Branched-chain amino acid ATP-binding cassette transporter PGHMIELC_02094 220668.lp_2983 4.5e-140 504.2 Lactobacillaceae livM ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 1TPMZ@1239,3F44M@33958,4HBB8@91061,COG4177@1,COG4177@2 NA|NA|NA E Branched-chain amino acid transport system / permease component PGHMIELC_02095 220668.lp_2984 6.5e-154 550.1 Lactobacillaceae livH ko:K01997 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 1TR24@1239,3F56V@33958,4HBFZ@91061,COG0559@1,COG0559@2 NA|NA|NA U Branched-chain amino acid transport system / permease component PGHMIELC_02096 220668.lp_2985 5.4e-212 743.4 Lactobacillaceae livJ ko:K01999 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 1TPQ2@1239,3F591@33958,4H9PI@91061,COG0683@1,COG0683@2 NA|NA|NA E Receptor family ligand binding region PGHMIELC_02098 220668.lp_2987 7e-33 146.0 Lactobacillaceae Bacteria 1U6KC@1239,29PH8@1,30AFD@2,3F83D@33958,4IGD6@91061 NA|NA|NA PGHMIELC_02099 220668.lp_2988 1.7e-113 415.6 Lactobacillaceae zmp3 Bacteria 1V6X9@1239,3F6QI@33958,4HK8S@91061,COG5549@1,COG5549@2 NA|NA|NA O Zinc-dependent metalloprotease PGHMIELC_02100 220668.lp_2989 2.8e-82 311.2 Lactobacillaceae gtrA GO:0000166,GO:0003674,GO:0003824,GO:0003870,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009987,GO:0016020,GO:0016410,GO:0016491,GO:0016620,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0016903,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 Bacteria 1U5D6@1239,3F5M1@33958,4IF4H@91061,COG2246@1,COG2246@2 NA|NA|NA S GtrA-like protein PGHMIELC_02101 220668.lp_2991 7.9e-122 443.4 Lactobacillaceae Bacteria 1VEKB@1239,3F84P@33958,4HH0D@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins PGHMIELC_02102 220668.lp_2992 4.1e-284 983.4 Lactobacillaceae mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 1TPT1@1239,3F49Y@33958,4HAEA@91061,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system PGHMIELC_02103 220668.lp_2993 6.8e-72 276.6 Lactobacillaceae Bacteria 1V8UY@1239,3F6N5@33958,4HK2J@91061,COG0589@1,COG0589@2 NA|NA|NA T Belongs to the universal stress protein A family PGHMIELC_02104 220668.lp_2994 4e-46 190.3 Lactobacillaceae Bacteria 1U6EW@1239,29PCQ@1,30AAY@2,3F7RQ@33958,4IG6Q@91061 NA|NA|NA PGHMIELC_02105 220668.lp_2995 1.9e-116 425.2 Lactobacillaceae Bacteria 1V6V7@1239,3F417@33958,4HITM@91061,COG0398@1,COG0398@2 NA|NA|NA S SNARE associated Golgi protein PGHMIELC_02106 60520.HR47_01805 2e-49 201.4 Lactobacillaceae Bacteria 1VA6G@1239,3F7DH@33958,4HKYT@91061,COG0640@1,COG0640@2 NA|NA|NA K Transcriptional regulator, ArsR family PGHMIELC_02107 220668.lp_2998 1.2e-95 355.9 Lactobacillaceae cadD Bacteria 1VUU3@1239,3F6NP@33958,4HVGH@91061,COG4300@1,COG4300@2 NA|NA|NA P Cadmium resistance transporter PGHMIELC_02108 220668.lp_3000 0.0 1187.2 Lactobacillaceae yhcA ko:K02003,ko:K02004,ko:K05685 ko02010,map02010 M00258,M00709 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 Bacteria 1TPBJ@1239,3F44P@33958,4HBK7@91061,COG0577@1,COG0577@2,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein PGHMIELC_02109 220668.lp_3001 0.0 1671.8 Lactobacillaceae Bacteria 1VTPR@1239,3F437@33958,4HJP1@91061,COG1409@1,COG1409@2,COG3119@1,COG3119@2 NA|NA|NA P Concanavalin A-like lectin/glucanases superfamily PGHMIELC_02110 220668.lp_3002 7.4e-64 249.6 Lactobacillaceae Bacteria 1U5VX@1239,29NZ7@1,309XC@2,3F6KY@33958,4IFJQ@91061 NA|NA|NA PGHMIELC_02111 220668.lp_3003 3.4e-160 570.9 Lactobacillaceae Bacteria 1UZK9@1239,3F5JR@33958,4HG1F@91061,COG0639@1,COG0639@2 NA|NA|NA T Calcineurin-like phosphoesterase superfamily domain PGHMIELC_02112 220668.lp_3004 3.6e-54 217.2 Lactobacillaceae Bacteria 1U6AA@1239,29P97@1,30A7B@2,3F7FH@33958,4IG1K@91061 NA|NA|NA PGHMIELC_02113 220668.lp_3006 2e-149 535.0 Lactobacillaceae dicA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 ko:K22300 ko00000,ko03000 Bacteria 1UI5I@1239,3F5XX@33958,4ISEH@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix domain PGHMIELC_02114 220668.lp_3008 6.8e-75 286.6 Lactobacillaceae pts23A ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1 Bacteria 1U5YM@1239,3F6QB@33958,4IFMP@91061,COG2190@1,COG2190@2 NA|NA|NA G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PGHMIELC_02115 220668.lp_3009 7e-53 213.0 Lactobacillaceae ptcB 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 Bacteria 1VADE@1239,3F77Q@33958,4HKG9@91061,COG1440@1,COG1440@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit PGHMIELC_02116 220668.lp_3010 3.5e-269 933.7 Lactobacillaceae pts23C ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 Bacteria 1VTVX@1239,3FC6X@33958,4HFKM@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane PGHMIELC_02117 220668.lp_3011 3.1e-280 970.3 Lactobacillaceae pbg6 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3FC7C@33958,4HDER@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family PGHMIELC_02118 220668.lp_3012 1.8e-184 651.7 Lactobacillaceae 1.1.1.219 ko:K00091 ko00000,ko01000 Bacteria 1UEMD@1239,3F5S3@33958,4HDN7@91061,COG0451@1,COG0451@2 NA|NA|NA GM Male sterility protein PGHMIELC_02119 220668.lp_3013 2.7e-76 291.2 Lactobacillaceae Bacteria 1V7AK@1239,3F78U@33958,4HJVT@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance PGHMIELC_02120 220668.lp_3014 2.3e-65 255.4 Lactobacillaceae Bacteria 1UI5H@1239,3F5QI@33958,4ISEG@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain PGHMIELC_02121 220668.lp_3015 2.3e-95 355.1 Lactobacillaceae Bacteria 1U5IQ@1239,3F61M@33958,4IF9G@91061,COG1388@1,COG1388@2 NA|NA|NA M Lysin motif PGHMIELC_02122 220668.lp_3016 4.7e-108 397.1 Lactobacillaceae Bacteria 1U7H5@1239,29Q4V@1,30B3N@2,3F9P5@33958,4IHDP@91061 NA|NA|NA S SdpI/YhfL protein family PGHMIELC_02123 220668.lp_3017 1.8e-54 218.4 Lactobacillaceae nudA Bacteria 1VEJD@1239,3F8KY@33958,4HNU5@91061,COG4043@1,COG4043@2 NA|NA|NA S ASCH PGHMIELC_02124 220668.lp_3018 9.1e-164 582.8 Lactobacillaceae psaA ko:K02077 M00244 ko00000,ko00002,ko02000 3.A.1.15 Bacteria 1V110@1239,3FBJR@33958,4HZ7G@91061,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family PGHMIELC_02125 220668.lp_3019 4.2e-92 344.0 Lactobacillaceae Bacteria 1U6CY@1239,29PB8@1,30A9F@2,3F7MS@33958,4IG4Q@91061 NA|NA|NA PGHMIELC_02126 220668.lp_3020 2e-120 438.3 Lactobacillaceae tag 3.2.2.20 ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1UYWG@1239,3F642@33958,4HGWW@91061,COG2818@1,COG2818@2 NA|NA|NA L Methyladenine glycosylase PGHMIELC_02127 220668.lp_3021 3.3e-219 767.3 Lactobacillaceae Bacteria 1TSW8@1239,3F4R9@33958,4HBT1@91061,COG2199@1,COG3706@2 NA|NA|NA T diguanylate cyclase PGHMIELC_02128 220668.lp_3022 1.2e-73 282.3 Lactobacillaceae Bacteria 1V7RA@1239,2DMPJ@1,32SWG@2,3F7QU@33958,4IG6C@91061 NA|NA|NA S Psort location Cytoplasmic, score PGHMIELC_02129 220668.lp_3023 2.1e-285 987.6 Lactobacillaceae dinB 2.7.7.7 ko:K02346,ko:K03502,ko:K14161 ko00000,ko01000,ko03400 Bacteria 1TP42@1239,3FCBJ@33958,4HFGA@91061,COG0389@1,COG0389@2 NA|NA|NA L impB/mucB/samB family C-terminal domain PGHMIELC_02130 220668.lp_3024 2.6e-166 591.3 Lactobacillaceae Bacteria 1TQWY@1239,3F75S@33958,4HW0R@91061,COG0583@1,COG0583@2 NA|NA|NA K Bacterial regulatory helix-turn-helix protein, lysR family PGHMIELC_02131 220668.lp_3025 6e-73 280.0 Lactobacillaceae Bacteria 1U6RC@1239,2B06A@1,31SH3@2,3F8CV@33958,4IGIR@91061 NA|NA|NA PGHMIELC_02132 220668.lp_3026 1.4e-130 472.2 Lactobacillaceae Bacteria 1TRHF@1239,3F3VA@33958,4HBXH@91061,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family PGHMIELC_02133 1136177.KCA1_2481 1.3e-175 622.9 Lactobacillaceae Bacteria 1UI5N@1239,3F5Z0@33958,4ISEK@91061,COG3069@1,COG3069@2 NA|NA|NA C C4-dicarboxylate transmembrane transporter activity PGHMIELC_02134 220668.lp_3029 3e-116 424.5 Lactobacillaceae Bacteria 1V7A7@1239,3F63T@33958,4HIII@91061,COG0702@1,COG0702@2 NA|NA|NA GM NAD(P)H-binding PGHMIELC_02135 220668.lp_3030 2.6e-91 341.3 Lactobacillaceae ko:K06910 ko00000 Bacteria 1U5RI@1239,3F6DG@33958,4IFFP@91061,COG1881@1,COG1881@2 NA|NA|NA S Phosphatidylethanolamine-binding protein PGHMIELC_02136 220668.lp_3031 2.3e-77 294.7 Lactobacillaceae yphH Bacteria 1TRVH@1239,3F6JT@33958,4HGCZ@91061,COG1917@1,COG1917@2 NA|NA|NA S Cupin domain PGHMIELC_02137 220668.lp_3032 2.4e-59 234.6 Lactobacillaceae Bacteria 1VWMQ@1239,3F8KM@33958,4IGQ3@91061,COG4925@1,COG4925@2 NA|NA|NA I sulfurtransferase activity PGHMIELC_02138 220668.lp_3033 2.5e-138 498.0 Lactobacillaceae Bacteria 1TRQC@1239,3F4FH@33958,4HD7P@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase PGHMIELC_02139 220668.lp_3034 3.6e-117 427.6 Lactobacillaceae Bacteria 1U573@1239,3F503@33958,4IEYN@91061,COG0702@1,COG0702@2 NA|NA|NA GM NAD(P)H-binding PGHMIELC_02140 220668.lp_3038 8.6e-218 762.7 Lactobacillaceae ykiI Bacteria 1VRBZ@1239,2DSXT@1,32UTZ@2,3F4NM@33958,4HT22@91061 NA|NA|NA PGHMIELC_02141 220668.lp_3040 0.0 1149.4 Lactobacillaceae ko:K06147,ko:K18892 ko02010,map02010 M00708 ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter PGHMIELC_02142 220668.lp_3042 4.8e-311 1072.8 Lactobacillaceae XK27_09600 ko:K06147,ko:K18891 ko02010,map02010 M00708 ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 Bacteria 1TP0B@1239,3F3SP@33958,4H9SC@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter, ATP-binding protein PGHMIELC_02143 220668.lp_3043 9.1e-177 626.3 Bacteria Bacteria COG5549@1,COG5549@2 NA|NA|NA O protein import PGHMIELC_02144 220668.lp_3044 3.7e-229 800.4 Lactobacillaceae amd 3.5.1.47 ko:K01436,ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPD7@1239,3FC42@33958,4H9WQ@91061,COG1473@1,COG1473@2 NA|NA|NA E Peptidase family M20/M25/M40 PGHMIELC_02145 220668.lp_3045 5e-162 577.0 Lactobacillaceae Bacteria 1TR53@1239,3F4IT@33958,4HB8Y@91061,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain PGHMIELC_02147 220668.lp_3047 1.4e-69 268.9 Lactobacillaceae Bacteria 1VYYP@1239,2CARX@1,34BQY@2,3F7EH@33958,4HYXX@91061 NA|NA|NA PGHMIELC_02148 220668.lp_3048 1.5e-144 518.8 Lactobacillaceae ko:K20391 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria 1U4VN@1239,3FBDK@33958,4IPPT@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins PGHMIELC_02149 220668.lp_3049 2.8e-266 924.1 Lactobacillaceae yjeM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1TRFS@1239,3F4J0@33958,4HA0N@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid PGHMIELC_02150 220668.lp_3050 3.9e-66 257.3 Lactobacillaceae lysM Bacteria 1U5V5@1239,3F6J1@33958,4IFIT@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain PGHMIELC_02151 220668.lp_3051 1.3e-223 781.9 Lactobacillaceae dhaT 1.1.1.1,1.1.1.202 ko:K00086,ko:K13954 ko00010,ko00071,ko00350,ko00561,ko00625,ko00626,ko00640,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00561,map00625,map00626,map00640,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02377,R03119,R04880,R05233,R05234,R06917,R06927 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649 ko00000,ko00001,ko01000 iYL1228.KPN_03491 Bacteria 1TPB4@1239,3F4SZ@33958,4HAPA@91061,COG1454@1,COG1454@2 NA|NA|NA C Dehydrogenase PGHMIELC_02152 220668.lp_3054 5.4e-214 750.0 Lactobacillaceae adhC 1.1.1.90 ko:K00055,ko:K06898 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 M00537,M00538 R01763,R02611,R04304,R05282,R05347,R05348 RC00087,RC00116 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP8E@1239,3F3QP@33958,4HAH9@91061,COG1062@1,COG1062@2 NA|NA|NA C Zn-dependent alcohol dehydrogenases, class III PGHMIELC_02153 220668.lp_3055 0.0 1137.1 Lactobacillaceae ctpA 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 1TP5S@1239,3F4IX@33958,4HAI0@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase PGHMIELC_02154 220668.lp_3057 6.4e-44 183.0 Lactobacillaceae silP 1.9.3.1,3.6.3.54 ko:K02275,ko:K17686 ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016 M00155 R00081,R00086 RC00002,RC00016 ko00000,ko00001,ko00002,ko01000 3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 1W06G@1239,3F7FA@33958,4HZAG@91061,COG4633@1,COG4633@2 NA|NA|NA S Cupredoxin-like domain PGHMIELC_02155 220668.lp_3058 2.6e-64 251.1 Lactobacillaceae silP 1.9.3.1,3.6.3.54 ko:K02275,ko:K17686 ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016 M00155 R00081,R00086 RC00002,RC00016 ko00000,ko00001,ko00002,ko01000 3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 1VE0E@1239,3F6KW@33958,4HMFJ@91061,COG4633@1,COG4633@2 NA|NA|NA S Cupredoxin-like domain PGHMIELC_02156 220668.lp_3059 0.0 2008.8 Lactobacillaceae ko:K03832 ko00000,ko02000 2.C.1.1 Bacteria 1UIXM@1239,3F5J8@33958,4ISVX@91061,COG0810@1,COG0810@2 NA|NA|NA M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins PGHMIELC_02157 220668.lp_3060 6e-140 503.4 Lactobacillaceae ko:K02529 ko00000,ko03000 Bacteria 1UI5R@1239,3F4P2@33958,4ISEM@91061,COG4977@1,COG4977@2 NA|NA|NA K Helix-turn-helix domain PGHMIELC_02158 220668.lp_3062 2.9e-38 164.1 Lactobacillaceae ko:K02890,ko:K07343 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEZU@1239,3F8KI@33958,4HQ97@91061,COG3743@1,COG3743@2 NA|NA|NA S TfoX C-terminal domain PGHMIELC_02159 220668.lp_3063 3.5e-228 797.3 Lactobacillaceae hpk9 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1W1ZJ@1239,3F4ZC@33958,4IEYA@91061,COG3290@1,COG3290@2 NA|NA|NA T GHKL domain PGHMIELC_02160 220668.lp_3064 4.2e-262 910.2 Lactobacillaceae Bacteria 1UFZZ@1239,2DTX9@1,33N2V@2,3F5CN@33958,4IF1S@91061 NA|NA|NA PGHMIELC_02161 220668.lp_3065 1.3e-75 288.9 Lactobacillaceae Bacteria 1U6H2@1239,29PEQ@1,30ACW@2,3F7WU@33958,4IG9B@91061 NA|NA|NA PGHMIELC_02162 220668.lp_3066 9.2e-187 659.4 Lactobacillaceae Bacteria 1V92G@1239,3F407@33958,4HIJ2@91061,COG4072@1,COG4072@2 NA|NA|NA S Cell surface protein PGHMIELC_02163 220668.lp_3067 1.7e-101 375.6 Lactobacillaceae Bacteria 1U5A5@1239,2DKIK@1,309KJ@2,3F5C2@33958,4IF1M@91061 NA|NA|NA S WxL domain surface cell wall-binding PGHMIELC_02164 220668.lp_3069 3e-176 624.4 Lactobacillaceae 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 1VSE2@1239,3F5BT@33958,4HUTX@91061,COG0604@1,COG0604@2 NA|NA|NA C Alcohol dehydrogenase GroES-like domain PGHMIELC_02165 220668.lp_3070 3.8e-69 267.3 Lactobacillaceae Bacteria 1U5KS@1239,2F916@1,309SE@2,3F65Y@33958,4IFBR@91061 NA|NA|NA S Iron-sulphur cluster biosynthesis PGHMIELC_02166 220668.lp_3071 2.5e-115 421.4 Lactobacillaceae Bacteria 1TQC2@1239,3F4JW@33958,4HH7M@91061,COG4832@1,COG4832@2 NA|NA|NA S GyrI-like small molecule binding domain PGHMIELC_02167 220668.lp_3072 5.2e-187 660.2 Lactobacillaceae Bacteria 1VCXS@1239,3F5HA@33958,4HKJG@91061,COG4072@1,COG4072@2 NA|NA|NA S Cell surface protein PGHMIELC_02168 220668.lp_3073 7.5e-101 373.2 Lactobacillaceae Bacteria 1U582@1239,2CH9P@1,309JF@2,3F53T@33958,4IEZC@91061 NA|NA|NA S WxL domain surface cell wall-binding PGHMIELC_02169 220668.lp_3074 1.1e-62 245.7 Lactobacillaceae Bacteria 1U6A8@1239,29P95@1,30A79@2,3F7F7@33958,4IG1G@91061 NA|NA|NA PGHMIELC_02170 220668.lp_3075 2.5e-212 745.7 Lactobacillaceae Bacteria 1UYD7@1239,3F5NI@33958,4HHUD@91061,COG4886@1,COG4886@2 NA|NA|NA NU Mycoplasma protein of unknown function, DUF285 PGHMIELC_02171 220668.lp_3077 2.3e-116 425.2 Lactobacillaceae Bacteria 1U59G@1239,29NNA@1,309K8@2,3F59P@33958,4IF0U@91061 NA|NA|NA PGHMIELC_02172 220668.lp_3078 3e-116 424.5 Lactobacillaceae Bacteria 1V1N8@1239,3F56K@33958,4HG58@91061,COG0637@1,COG0637@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase PGHMIELC_02173 220668.lp_3081 2e-61 241.5 Lactobacillaceae Bacteria 1V43K@1239,3F6PX@33958,4HH01@91061,COG1733@1,COG1733@2 NA|NA|NA K Transcriptional regulator, HxlR family PGHMIELC_02174 220668.lp_3082 4.9e-213 746.9 Lactobacillaceae ytbD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K19577 ko00000,ko02000 2.A.1.2.65 Bacteria 1TRNU@1239,3FCA6@33958,4HCSX@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_02175 220668.lp_3084 1.6e-93 349.0 Lactobacillaceae Bacteria 1V4KP@1239,3F6PH@33958,4HIBF@91061,COG1376@1,COG1376@2 NA|NA|NA M ErfK YbiS YcfS YnhG PGHMIELC_02176 220668.lp_3085 0.0 1286.6 Lactobacillaceae asnB GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 1TRPB@1239,3F3NT@33958,4HAIP@91061,COG0367@1,COG0367@2 NA|NA|NA E Asparagine synthase PGHMIELC_02177 220668.lp_3087 5.7e-135 486.9 Lactobacillaceae ko:K07707 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko02022 Bacteria 1V392@1239,3F6N8@33958,4HHAI@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain PGHMIELC_02178 220668.lp_3088 8.3e-186 656.4 Lactobacillaceae 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1V1ET@1239,3F7J2@33958,4HGNA@91061,COG3290@1,COG3290@2 NA|NA|NA T GHKL domain PGHMIELC_02179 220668.lp_3090 7.9e-100 369.8 Lactobacillaceae fadR Bacteria 1U51T@1239,3F40Q@33958,4IETF@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family PGHMIELC_02180 220668.lp_3091 1.1e-167 595.9 Lactobacillaceae Bacteria 1V9EI@1239,3F4GJ@33958,4HJCA@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family PGHMIELC_02181 220668.lp_3092 9.1e-267 925.6 Lactobacillaceae gabD 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4S@1239,3F47F@33958,4H9MF@91061,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family PGHMIELC_02182 220668.lp_3093 0.0 1116.7 Lactobacillaceae ko:K07273 ko00000 Bacteria 1V3SH@1239,3F63N@33958,4HNR1@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 PGHMIELC_02183 220668.lp_3094 8.5e-47 192.6 Lactobacillaceae Bacteria 1VA6D@1239,3F7HB@33958,4HXXX@91061,COG4430@1,COG4430@2 NA|NA|NA S Domain of unknown function (DUF1905) PGHMIELC_02184 220668.lp_3095 3.7e-63 247.3 Lactobacillaceae hxlR Bacteria 1VA9M@1239,3F6U8@33958,4HNAK@91061,COG1733@1,COG1733@2 NA|NA|NA K HxlR-like helix-turn-helix PGHMIELC_02185 220668.lp_3096 9.8e-132 476.1 Lactobacillaceae ydfG Bacteria 1TRHF@1239,3FC9K@33958,4IPPS@91061,COG4221@1,COG4221@2 NA|NA|NA S KR domain PGHMIELC_02186 220668.lp_3097 3.2e-98 364.4 Lactobacillaceae Bacteria 1VBRZ@1239,3F62W@33958,4HXJE@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family PGHMIELC_02187 220668.lp_3098 1.2e-191 675.6 Lactobacillaceae 1.1.1.219 ko:K00091 ko00000,ko01000 Bacteria 1UEMD@1239,3F5S3@33958,4HDN7@91061,COG0451@1,COG0451@2 NA|NA|NA GM Male sterility protein PGHMIELC_02188 220668.lp_3099 4.1e-101 374.0 Lactobacillaceae Bacteria 1VFW9@1239,3F4JD@33958,4HR1J@91061,COG3548@1,COG3548@2 NA|NA|NA S Protein of unknown function (DUF1211) PGHMIELC_02189 220668.lp_3100 1.5e-180 638.6 Lactobacillaceae Bacteria 1TQ12@1239,3F4U1@33958,4HA57@91061,COG4989@1,COG4989@2 NA|NA|NA S Aldo keto reductase PGHMIELC_02192 60520.HR47_04085 6e-253 879.8 Lactobacillaceae yfjF Bacteria 1UI5Q@1239,3FBS9@33958,4HYNY@91061,COG0477@1,COG0477@2 NA|NA|NA U Sugar (and other) transporter PGHMIELC_02193 220668.lp_3102 4.3e-109 400.6 Lactobacillaceae Bacteria 1V2M4@1239,3F6MM@33958,4HMH5@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family PGHMIELC_02194 220668.lp_3103 1.2e-169 602.4 Lactobacillaceae fhuD ko:K02016 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 1TQMK@1239,3F4YN@33958,4HBP4@91061,COG0614@1,COG0614@2 NA|NA|NA P Periplasmic binding protein PGHMIELC_02195 220668.lp_3104 1.1e-144 519.2 Lactobacillaceae fhuC 3.6.3.34 ko:K02013 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 Bacteria 1TP2Q@1239,3FC36@33958,4HADG@91061,COG1120@1,COG1120@2 NA|NA|NA HP ABC transporter PGHMIELC_02196 220668.lp_3105 2.1e-177 628.2 Lactobacillaceae sirB ko:K02015 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 1TP13@1239,3FCBQ@33958,4HA75@91061,COG0609@1,COG0609@2 NA|NA|NA U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily PGHMIELC_02197 220668.lp_3106 7.8e-172 609.8 Lactobacillaceae fhuG ko:K02015 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 1TPX6@1239,3F4T9@33958,4H9QQ@91061,COG0609@1,COG0609@2 NA|NA|NA U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily PGHMIELC_02198 220668.lp_3107 5.4e-92 343.6 Lactobacillaceae Bacteria 1UV2D@1239,3F8X9@33958,4HZAY@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family PGHMIELC_02199 220668.lp_3108 4.1e-164 583.9 Bacilli Bacteria 1V0SH@1239,4HPN7@91061,COG0451@1,COG0451@2 NA|NA|NA GM NmrA-like family PGHMIELC_02200 220668.lp_3110 2.5e-130 471.5 Lactobacillaceae Bacteria 1TRHF@1239,3F468@33958,4HBXH@91061,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family PGHMIELC_02201 220668.lp_3111 1.3e-68 265.8 Lactobacillaceae maa Bacteria 1TSQQ@1239,3F73Z@33958,4HJJ7@91061,COG0110@1,COG0110@2 NA|NA|NA S transferase hexapeptide repeat PGHMIELC_02202 220668.lp_3112 7.5e-152 543.1 Lactobacillaceae ko:K07124 ko00000 Bacteria 1TRQB@1239,3F3M7@33958,4HAY3@91061,COG0300@1,COG0300@2,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase PGHMIELC_02203 220668.lp_3113 1.6e-64 251.9 Lactobacillaceae Bacteria 1U7N9@1239,3F9XX@33958,4IHJI@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance PGHMIELC_02204 220668.lp_3114 0.0 2915.9 Lactobacillaceae pelX GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0044877,GO:0051704,GO:0070051,GO:0098630,GO:0098743 ko:K14194,ko:K14201,ko:K20276 ko02024,ko05150,map02024,map05150 ko00000,ko00001 Bacteria 1VSP5@1239,3F4FY@33958,4HUK1@91061,COG3266@1,COG3266@2 NA|NA|NA UW LPXTG-motif cell wall anchor domain protein PGHMIELC_02205 220668.lp_3114 2e-39 168.3 Lactobacillaceae pelX GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0044877,GO:0051704,GO:0070051,GO:0098630,GO:0098743 ko:K14194,ko:K14201,ko:K20276 ko02024,ko05150,map02024,map05150 ko00000,ko00001 Bacteria 1VSP5@1239,3F4FY@33958,4HUK1@91061,COG3266@1,COG3266@2 NA|NA|NA UW LPXTG-motif cell wall anchor domain protein PGHMIELC_02206 220668.lp_3115 6.1e-15 86.3 Lactobacillaceae Bacteria 1U51H@1239,3F5KF@33958,4IET6@91061,COG4072@1,COG4072@2 NA|NA|NA S Bacterial protein of unknown function (DUF916) PGHMIELC_02207 220668.lp_3115 6.1e-132 476.9 Lactobacillaceae Bacteria 1U51H@1239,3F5KF@33958,4IET6@91061,COG4072@1,COG4072@2 NA|NA|NA S Bacterial protein of unknown function (DUF916) PGHMIELC_02208 220668.lp_3116 8.7e-83 313.2 Lactobacillaceae Bacteria 1UQXW@1239,2CH9P@1,324R5@2,3F6RK@33958,4IFNM@91061 NA|NA|NA S WxL domain surface cell wall-binding PGHMIELC_02209 220668.lp_3117 1.7e-179 636.3 Lactobacillaceae Bacteria 1UYD7@1239,3F5NI@33958,4HHUD@91061,COG4886@1,COG4886@2,COG4932@1,COG4932@2 NA|NA|NA NU Mycoplasma protein of unknown function, DUF285 PGHMIELC_02210 220668.lp_3119 1.4e-116 425.6 Lactobacillaceae Bacteria 1VG5A@1239,3F6MB@33958,4HP2P@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family PGHMIELC_02211 220668.lp_3120 0.0 1151.7 Lactobacillaceae lepA ko:K03596 ko05134,map05134 ko00000,ko00001 Bacteria 1VSME@1239,3F4V3@33958,4HTAG@91061,COG0481@1,COG0481@2 NA|NA|NA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner PGHMIELC_02212 220668.lp_3122 3.5e-291 1006.9 Lactobacillaceae yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 1TR4G@1239,3F42V@33958,4HBJR@91061,COG0025@1,COG0025@2 NA|NA|NA P Sodium proton antiporter PGHMIELC_02213 220668.lp_3123 1.5e-152 545.4 Lactobacillaceae nudC 1.3.7.1,3.6.1.22 ko:K03426,ko:K20449 ko00760,ko01100,ko01120,ko04146,map00760,map01100,map01120,map04146 R00103,R03004,R03164,R11104 RC00002,RC02422 ko00000,ko00001,ko01000 Bacteria 1TRMF@1239,3F5W0@33958,4HKK0@91061,COG2816@1,COG2816@2 NA|NA|NA L NADH pyrophosphatase zinc ribbon domain PGHMIELC_02214 220668.lp_3124 8.7e-162 576.2 Lactobacillaceae Bacteria 1V1MH@1239,3F527@33958,4HFVE@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain PGHMIELC_02215 220668.lp_3125 8.6e-284 982.2 Lactobacillaceae 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 1TT1Q@1239,3F4DI@33958,4IPXT@91061,COG1053@1,COG1053@2 NA|NA|NA C FAD binding domain PGHMIELC_02216 220668.lp_3127 0.0 1284.2 Lactobacillaceae 3.2.1.4,3.2.1.78,3.2.1.8 ko:K01179,ko:K01181,ko:K01218 ko00051,ko00500,ko01100,ko02024,map00051,map00500,map01100,map02024 R01332,R06200,R11307,R11308 RC00467 ko00000,ko00001,ko01000 GH26,GH5,GH9 Bacteria 1UIXN@1239,3FBTR@33958,4ISVY@91061,COG4886@1,COG4886@2 NA|NA|NA S MucBP domain PGHMIELC_02217 1074451.CRL705_1934 1.7e-84 318.5 Lactobacillaceae dps ko:K04047 ko00000,ko03036 Bacteria 1VCVJ@1239,3F5WI@33958,4HMBD@91061,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family PGHMIELC_02218 1136177.KCA1_2563 2.2e-115 421.8 Lactobacillaceae GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 ko:K03489 ko00000,ko03000 Bacteria 1V4DC@1239,3F6TC@33958,4HIDU@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA PGHMIELC_02219 1136177.KCA1_2564 4.4e-269 933.3 Lactobacillaceae celA 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family PGHMIELC_02220 1136177.KCA1_2565 1.6e-247 861.7 Lactobacillaceae celD ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 Bacteria 1TP8D@1239,3FC70@33958,4HDVN@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane PGHMIELC_02221 1136177.KCA1_2566 4.1e-65 254.2 Lactobacillaceae Bacteria 1UHKX@1239,2E5MG@1,32WCE@2,3F64Q@33958,4IS3T@91061 NA|NA|NA PGHMIELC_02222 220668.lp_3129 1.5e-11 75.1 Lactobacillaceae Bacteria 1U81W@1239,2BPRH@1,32IIS@2,3FAFB@33958,4IHZ9@91061 NA|NA|NA PGHMIELC_02223 568703.LGG_01348 1e-29 136.0 Lactobacillaceae pcaC 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R03470 RC00938 ko00000,ko00001,ko01000 Bacteria 1V78I@1239,3F5I2@33958,4HKFY@91061,COG0599@1,COG0599@2 NA|NA|NA S Carboxymuconolactone decarboxylase family PGHMIELC_02224 1423734.JCM14202_438 1.3e-23 115.9 Lactobacillaceae rmeD ko:K13640 ko00000,ko03000 Bacteria 1VB69@1239,3FC69@33958,4HN6R@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance PGHMIELC_02225 220668.lp_3134 7.6e-64 249.6 Lactobacillaceae Bacteria 1VF0I@1239,3F83V@33958,4HPC2@91061,COG5294@1,COG5294@2 NA|NA|NA S Protein of unknown function (DUF1093) PGHMIELC_02226 220668.lp_3139 1.5e-207 728.8 Lactobacillaceae Bacteria 1UI8W@1239,3F6SG@33958,4ISGD@91061,COG3152@1,COG3152@2 NA|NA|NA S Membrane PGHMIELC_02227 220668.lp_3141 1.9e-43 181.4 Lactobacillaceae Bacteria 1U77Z@1239,29WTM@1,30IF0@2,3F93A@33958,4IH2S@91061 NA|NA|NA S Protein of unknown function (DUF3781) PGHMIELC_02228 220668.lp_3142 4e-107 394.0 Lactobacillaceae ydeA Bacteria 1V1TX@1239,3F69P@33958,4HDNJ@91061,COG0693@1,COG0693@2 NA|NA|NA S intracellular protease amidase PGHMIELC_02229 220668.lp_3143 8.3e-41 172.6 Lactobacillaceae Bacteria 1VA9M@1239,3F8HF@33958,4IE7V@91061,COG1733@1,COG1733@2 NA|NA|NA K HxlR-like helix-turn-helix PGHMIELC_02230 1423816.BACQ01000047_gene1754 1.9e-66 260.0 Lactobacillaceae Bacteria 1VX2D@1239,2C4MM@1,340I6@2,3F7DW@33958,4HWVM@91061 NA|NA|NA PGHMIELC_02231 1400520.LFAB_05710 1.3e-64 253.1 Lactobacillaceae ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1VR4S@1239,3F6J7@33958,4HUU8@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter PGHMIELC_02232 1423816.BACQ01000047_gene1756 2.3e-51 208.8 Lactobacillaceae Bacteria 1UJ7F@1239,3F8EQ@33958,4IT3K@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix domain PGHMIELC_02233 220668.lp_3150 3.8e-204 717.2 Lactobacillaceae mdh 1.1.1.350 ko:K00073 ko00230,ko01120,map00230,map01120 R02935,R02936 RC00169 ko00000,ko00001,ko01000 Bacteria 1TR0Z@1239,3F4JZ@33958,4HB6X@91061,COG2055@1,COG2055@2 NA|NA|NA C Belongs to the LDH2 MDH2 oxidoreductase family PGHMIELC_02234 220668.lp_3154 2.5e-36 158.3 Lactobacillaceae 3.2.1.17,3.4.17.14,3.5.1.28 ko:K01185,ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 M00651,M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 Bacteria 1UYRM@1239,3F4XJ@33958,4HAU6@91061,COG1705@1,COG1705@2 NA|NA|NA NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase PGHMIELC_02235 220668.lp_3155 1.1e-100 372.9 Lactobacillaceae Bacteria 1V4KP@1239,3F6PH@33958,4HIBF@91061,COG1376@1,COG1376@2 NA|NA|NA M ErfK YbiS YcfS YnhG PGHMIELC_02236 1400520.LFAB_17025 5.9e-112 410.6 Lactobacillaceae akr5f 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 1TPM1@1239,3FB4Q@33958,4H9XJ@91061,COG0656@1,COG0656@2 NA|NA|NA S reductase PGHMIELC_02237 220668.lp_3158 3.7e-108 397.5 Lactobacillaceae Bacteria 1UJSC@1239,3F60E@33958,4HGYK@91061,COG0702@1,COG0702@2 NA|NA|NA GM NAD(P)H-binding PGHMIELC_02238 220668.lp_3159 3.2e-77 294.3 Lactobacillaceae 3.5.4.1 ko:K01485,ko:K21572 ko00240,ko00330,ko01100,map00240,map00330,map01100 R00974,R01411,R02922 RC00074,RC00514,RC00809 ko00000,ko00001,ko01000,ko02000 8.A.46.1,8.A.46.3 Bacteria 1VF1R@1239,3F93P@33958,4IH31@91061,COG0702@1,COG0702@2 NA|NA|NA GM SnoaL-like domain PGHMIELC_02239 220668.lp_3160 7.2e-259 899.4 Lactobacillaceae qacA Bacteria 1VSW8@1239,3F9E0@33958,4HUQC@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Fungal trichothecene efflux pump (TRI12) PGHMIELC_02240 220668.lp_3161 9.2e-65 252.7 Lactobacillaceae Bacteria 1U676@1239,29WTN@1,30IF1@2,3F8FU@33958,4IFXS@91061 NA|NA|NA S Domain of unknown function (DUF4440) PGHMIELC_02241 220668.lp_3164 2.4e-104 384.8 Lactobacillaceae Bacteria 1VFA9@1239,3F6J9@33958,4IFIV@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family PGHMIELC_02243 220668.lp_3168 6.8e-33 146.0 Lactobacillaceae ko:K07483 ko00000 Bacteria 1UUZ4@1239,3F7VV@33958,4IG8V@91061,COG2963@1,COG2963@2 NA|NA|NA L transposase activity PGHMIELC_02245 220668.lp_3169 8.8e-40 169.1 Lactobacillaceae Bacteria 1U6CS@1239,29PB4@1,30A9A@2,3F7MC@33958,4IG4H@91061 NA|NA|NA PGHMIELC_02246 220668.lp_3170 7.9e-131 473.0 Lactobacillaceae gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1TQFP@1239,3F3SK@33958,4HAW7@91061,COG0588@1,COG0588@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate PGHMIELC_02247 220668.lp_3171 1.9e-171 608.6 Lactobacillaceae Bacteria 1TSBK@1239,3F46E@33958,4HBYJ@91061,COG0628@1,COG0628@2 NA|NA|NA K AI-2E family transporter PGHMIELC_02248 220668.lp_3172 8.3e-210 736.1 Lactobacillaceae xylR Bacteria 1TQCE@1239,3F540@33958,4HDE3@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family PGHMIELC_02249 220668.lp_3173 7.8e-82 310.8 Lactobacillaceae Bacteria 1VM03@1239,2EIB1@1,33C2F@2,3F5MI@33958,4HS05@91061 NA|NA|NA PGHMIELC_02250 220668.lp_3174 4.7e-232 810.1 Lactobacillaceae cfa 2.1.1.317,2.1.1.79 ko:K00574,ko:K20238 ko00000,ko01000 Bacteria 1TSG4@1239,3F3PA@33958,4HDKI@91061,COG2230@1,COG2230@2 NA|NA|NA M cyclopropane-fatty-acyl-phospholipid synthase PGHMIELC_02251 220668.lp_3175 3.6e-163 580.9 Lactobacillaceae Bacteria 1V602@1239,28JAP@1,2Z95J@2,3F4EN@33958,4IVBI@91061 NA|NA|NA PGHMIELC_02252 220668.lp_3176 2e-202 711.4 Lactobacillaceae Bacteria 1V7U3@1239,3F5QP@33958,4HKIZ@91061,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase PGHMIELC_02253 220668.lp_3177 6.8e-25 120.2 Lactobacillaceae Bacteria 1VASH@1239,2E61F@1,330QP@2,3F777@33958,4HKBT@91061 NA|NA|NA S Protein of unknown function (DUF4064) PGHMIELC_02254 220668.lp_3178 6e-97 360.1 Lactobacillaceae Bacteria 1VFZ2@1239,2DPC1@1,331GC@2,3FBNK@33958,4IRCJ@91061 NA|NA|NA S Domain of unknown function (DUF4352) PGHMIELC_02255 220668.lp_3179 3.9e-75 287.3 Lactobacillaceae Bacteria 1VGFJ@1239,2E529@1,32ZVG@2,3F6D6@33958,4IFFI@91061 NA|NA|NA S Psort location Cytoplasmic, score PGHMIELC_02256 220668.lp_3180 4.8e-55 220.3 Lactobacillaceae Bacteria 1U6SM@1239,2B3UH@1,31WIC@2,3F8F1@33958,4IGK6@91061 NA|NA|NA PGHMIELC_02257 60520.HR47_05710 1.6e-110 405.6 Lactobacillaceae ko:K07090 ko00000 Bacteria 1VBCY@1239,3F41D@33958,4HSSU@91061,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein PGHMIELC_02258 1136177.KCA1_2610 2.3e-54 218.0 Lactobacillaceae azlD Bacteria 1UF1S@1239,3F7GD@33958,4HQ7J@91061,COG4392@1,COG4392@2 NA|NA|NA S branched-chain amino acid PGHMIELC_02259 220668.lp_3185 5.1e-131 473.8 Lactobacillaceae azlC Bacteria 1U49T@1239,3F45S@33958,4HDIJ@91061,COG1296@1,COG1296@2 NA|NA|NA E branched-chain amino acid PGHMIELC_02260 220668.lp_3187 1.3e-90 339.0 Lactobacillaceae ywnH GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 Bacteria 1V3V3@1239,3F70T@33958,4HHNY@91061,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase (GNAT) domain PGHMIELC_02261 220668.lp_3189 4.9e-238 830.1 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1TQN0@1239,3F43S@33958,4HBD4@91061,COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family PGHMIELC_02262 220668.lp_3190 1.3e-213 748.8 Lactobacillaceae hpk31 2.7.13.3 ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TPB6@1239,3F479@33958,4HARU@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase PGHMIELC_02263 220668.lp_3191 3.2e-124 451.1 Lactobacillaceae Bacteria 1TP9M@1239,3F3Y0@33958,4HB3T@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator PGHMIELC_02264 220668.lp_3192 5.5e-124 450.3 Lactobacillaceae yoaK Bacteria 1V1VQ@1239,3F5F5@33958,4HM4F@91061,COG3619@1,COG3619@2 NA|NA|NA S Protein of unknown function (DUF1275) PGHMIELC_02265 220668.lp_3193 2.9e-160 571.2 Lactobacillaceae prsA 3.1.3.16,5.2.1.8 ko:K01802,ko:K03769,ko:K07533,ko:K20074 ko00000,ko01000,ko01009,ko03110 Bacteria 1TX3R@1239,3F9BD@33958,4HC85@91061,COG0760@1,COG0760@2 NA|NA|NA M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins PGHMIELC_02266 220668.lp_3194 2.3e-212 744.6 Lactobacillaceae guaB GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027 Bacteria 1TNZ1@1239,3F3XN@33958,4H9V3@91061,COG0516@1,COG0516@2 NA|NA|NA F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides PGHMIELC_02267 220668.lp_3195 5.2e-125 453.8 Lactobacillaceae XK27_01040 Bacteria 1VF5N@1239,3F4JS@33958,4HH7B@91061,COG4858@1,COG4858@2 NA|NA|NA S Protein of unknown function (DUF1129) PGHMIELC_02268 220668.lp_3196 2e-200 704.9 Lactobacillaceae ychF GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 ko:K06942 ko00000,ko03009 Bacteria 1TPRK@1239,3F3TK@33958,4H9SQ@91061,COG0012@1,COG0012@2 NA|NA|NA J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner PGHMIELC_02269 1136177.KCA1_2620 9.8e-31 138.7 Lactobacillaceae yyzM Bacteria 1VEQ7@1239,3F823@33958,4HNHU@91061,COG4481@1,COG4481@2 NA|NA|NA S Bacterial protein of unknown function (DUF951) PGHMIELC_02270 220668.lp_3198 1.2e-155 555.8 Lactobacillaceae spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 1TQ2B@1239,3F47R@33958,4H9TB@91061,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family PGHMIELC_02271 60520.HR47_05635 1.8e-136 491.9 Lactobacillaceae soj ko:K03496 ko00000,ko03036,ko04812 Bacteria 1TP8S@1239,3F4AE@33958,4HAYM@91061,COG1192@1,COG1192@2 NA|NA|NA D Sporulation initiation inhibitor PGHMIELC_02272 220668.lp_3200 2.7e-149 534.6 Lactobacillaceae noc ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 1TP0I@1239,3F4RU@33958,4HAC6@91061,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family PGHMIELC_02273 220668.lp_3201 2.4e-130 471.5 Lactobacillaceae rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 ko00000,ko01000,ko03009,ko03036 Bacteria 1TPBT@1239,3F3ZX@33958,4HAAZ@91061,COG0357@1,COG0357@2 NA|NA|NA J Specifically methylates the N7 position of a guanine in 16S rRNA PGHMIELC_02274 220668.lp_3204 4.1e-226 790.4 Lactobacillaceae nupG GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015212,GO:0015213,GO:0015214,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015506,GO:0015672,GO:0015858,GO:0015861,GO:0015862,GO:0015864,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072531,GO:0098655,GO:0098660,GO:0098662,GO:1901264,GO:1901505,GO:1901642,GO:1902600 ko:K03317,ko:K16323 ko00000,ko02000 2.A.41,2.A.41.1 Bacteria 1TRSK@1239,3F4GI@33958,4HA8N@91061,COG1972@1,COG1972@2 NA|NA|NA F Nucleoside PGHMIELC_02275 60520.HR47_05615 0.0 1675.6 Lactobacillaceae Bacteria 1TPVY@1239,3F4AK@33958,4HD9X@91061,COG4485@1,COG4485@2 NA|NA|NA S Bacterial membrane protein YfhO PGHMIELC_02276 220668.lp_3205 4.3e-147 527.3 Lactobacillaceae Bacteria 1U56H@1239,3F4XW@33958,4IEXS@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF915) PGHMIELC_02277 220668.lp_3206 2.1e-168 598.2 Lactobacillaceae Bacteria 1TP9T@1239,3F4HW@33958,4HCXX@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain PGHMIELC_02278 220668.lp_3207 2.7e-235 820.8 Lactobacillaceae Bacteria 1TPS5@1239,3F4AH@33958,4H9M3@91061,COG1167@1,COG1167@2 NA|NA|NA EK Aminotransferase, class I PGHMIELC_02279 60520.HR47_05580 1.8e-126 458.8 Lactobacillaceae tcyA ko:K02424,ko:K10009 ko02010,map02010 M00234 ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 Bacteria 1UFZS@1239,3FC54@33958,4HD9I@91061,COG0834@1,COG0834@2 NA|NA|NA ET Belongs to the bacterial solute-binding protein 3 family PGHMIELC_02280 220668.lp_3210 8.1e-123 446.4 Lactobacillaceae tcyB GO:0000099,GO:0000101,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015184,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015811,GO:0015849,GO:0016020,GO:0022857,GO:0033229,GO:0034220,GO:0042883,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:0098655,GO:0098656,GO:1901682,GO:1902475,GO:1903712,GO:1903825,GO:1905039 ko:K02424,ko:K10009 ko02010,map02010 M00234 ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 iYO844.BSU03600 Bacteria 1TPQ8@1239,3F4QR@33958,4H9N1@91061,COG0765@1,COG0765@2 NA|NA|NA E ABC transporter PGHMIELC_02281 220668.lp_3211 3.6e-137 494.2 Lactobacillaceae glnQ 3.6.3.21 ko:K02028,ko:K10010 ko02010,map02010 M00234,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.10,3.A.1.3.14 Bacteria 1TNYD@1239,3F4YF@33958,4HUHS@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein PGHMIELC_02282 220668.lp_3214 3.3e-120 438.0 Lactobacillaceae tcyA ko:K02424,ko:K10009 ko02010,map02010 M00234 ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 Bacteria 1TR13@1239,3F4MH@33958,4HBRP@91061,COG0834@1,COG0834@2 NA|NA|NA ET Belongs to the bacterial solute-binding protein 3 family PGHMIELC_02283 220668.lp_3215 2.9e-78 298.1 Bacteria Bacteria COG4640@1,COG4640@2 NA|NA|NA KT response to antibiotic PGHMIELC_02284 220668.lp_3216 6.8e-53 213.0 Lactobacillaceae ko:K10947 ko00000,ko03000 Bacteria 1VACN@1239,3FCDA@33958,4HQIW@91061,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PGHMIELC_02285 220668.lp_3217 5.1e-84 317.4 Lactobacillaceae XK27_06920 Bacteria 1VD2S@1239,3FBMR@33958,4HN8T@91061,COG4709@1,COG4709@2 NA|NA|NA S Protein of unknown function (DUF1700) PGHMIELC_02286 220668.lp_3218 5e-128 464.2 Lactobacillaceae Bacteria 1VJU7@1239,3F6HR@33958,4HQ8U@91061,COG3595@1,COG3595@2 NA|NA|NA S Putative adhesin PGHMIELC_02287 220668.lp_3219 0.0 1198.7 Lactobacillaceae scrA 2.7.1.193,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02802,ko:K02803,ko:K02804,ko:K02808,ko:K02809,ko:K02810 ko00500,ko00520,ko02060,map00500,map00520,map02060 M00267,M00269,M00271 R00811,R05199 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system PGHMIELC_02288 220668.lp_3220 0.0 1158.3 Lactobacillaceae malA 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13,GH31 Bacteria 1TP53@1239,3F41I@33958,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain protein PGHMIELC_02289 220668.lp_3221 3.2e-181 641.0 Lactobacillaceae 5.1.1.1 ko:K01775,ko:K02529,ko:K05499 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011,ko03000 Bacteria 1TRHK@1239,3F5FI@33958,4HB9P@91061,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding proteins and sugar binding domain of LacI family PGHMIELC_02290 220668.lp_3223 1.3e-204 718.8 Lactobacillaceae Bacteria 1UR34@1239,3F4J5@33958,4HDF2@91061,COG1434@1,COG1434@2 NA|NA|NA S DUF218 domain PGHMIELC_02291 220668.lp_3224 2e-127 461.8 Lactobacillaceae ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 ko:K02069 M00211 ko00000,ko00002,ko02000 9.B.25.1 Bacteria 1UY1N@1239,3F4P1@33958,4HDM4@91061,COG0390@1,COG0390@2 NA|NA|NA S Uncharacterised protein family (UPF0014) PGHMIELC_02292 220668.lp_3225 9.4e-118 429.5 Lactobacillaceae ybbL GO:0005575,GO:0005623,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0016020,GO:0019725,GO:0030003,GO:0042592,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071944,GO:0098771 ko:K02065,ko:K02068 ko02010,map02010 M00210,M00211,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1V3DQ@1239,3F4UY@33958,4HHGU@91061,COG4619@1,COG4619@2 NA|NA|NA S ABC transporter, ATP-binding protein PGHMIELC_02293 220668.lp_3226 4.2e-275 953.4 Lactobacillaceae rumA 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 ko00000,ko01000,ko03009,ko03016 Bacteria 1TP4H@1239,3F4GQ@33958,4HA6M@91061,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family PGHMIELC_02294 220668.lp_3227 1.2e-76 292.4 Lactobacillaceae Bacteria 1U5AV@1239,2AC8T@1,311TG@2,3F5EK@33958,4IF2B@91061 NA|NA|NA PGHMIELC_02295 220668.lp_3236 6.5e-151 540.0 Lactobacillaceae qorB 1.6.5.2 ko:K19267 ko00130,ko01110,map00130,map01110 R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 Bacteria 1TT90@1239,3F4UU@33958,4HC1K@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family PGHMIELC_02296 220668.lp_3237 9.4e-147 526.2 Lactobacillaceae cof Bacteria 1TSGF@1239,3F57T@33958,4HHWU@91061,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase PGHMIELC_02297 220668.lp_3637 1.1e-92 346.7 Lactobacillaceae scrK 2.7.1.2,2.7.1.4 ko:K00845,ko:K00847 ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R00760,R00867,R01600,R01786,R03920 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQU4@1239,3F3K8@33958,4HA1C@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family PGHMIELC_02298 1545702.LACWKB8_1360 4e-308 1063.9 Lactobacillaceae mngB 3.2.1.170,3.2.1.24 ko:K01191,ko:K15524 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 GH38 Bacteria 1TQEH@1239,3F4XS@33958,4HBC7@91061,COG0383@1,COG0383@2 NA|NA|NA G Glycosyl hydrolases family 38 N-terminal domain PGHMIELC_02299 1140002.I570_00535 2.8e-122 445.3 Enterococcaceae mngA 2.7.1.195,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K11198,ko:K11199,ko:K11200 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273,M00305 R03232,R11169 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.2.1.3 Bacteria 1U5J4@1239,4B0SC@81852,4HDDR@91061,COG1299@1,COG1299@2 NA|NA|NA U Phosphotransferase system, EIIC PGHMIELC_02300 1410674.JNKU01000043_gene113 2.4e-26 124.8 Lactobacillaceae mngA 2.7.1.195,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K11198,ko:K11199,ko:K11200 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273,M00305 R03232,R11169 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.2.1.3 Bacteria 1V77Q@1239,3FBBP@33958,4HJJ9@91061,COG1445@1,COG1445@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit PGHMIELC_02301 985665.HPL003_08670 1.7e-20 105.9 Paenibacillaceae fryA 2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K03483,ko:K03491 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1 Bacteria 1V54T@1239,26Y31@186822,4HKX6@91061,COG1762@1,COG1762@2 NA|NA|NA G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) PGHMIELC_02302 208596.CAR_c23420 2.2e-90 340.1 Carnobacteriaceae 2.7.1.194,2.7.1.200,2.7.1.202 ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03483,ko:K03491 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00550 R03232,R05570,R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5.1,4.A.7.1 Bacteria 1TQT1@1239,27HGM@186828,4HB6A@91061,COG1762@1,COG1762@2,COG3711@1,COG3711@2 NA|NA|NA GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 PGHMIELC_02303 220668.lp_3238 2e-77 295.0 Lactobacillaceae merR ko:K21089,ko:K21972,ko:K22491 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 1U5BW@1239,3F5GN@33958,4IF2X@91061,COG0789@1,COG0789@2 NA|NA|NA K MerR family regulatory protein PGHMIELC_02304 220668.lp_3239 2.6e-155 554.7 Lactobacillaceae 1.6.5.2 ko:K19267 ko00130,ko01110,map00130,map01110 R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 Bacteria 1TT90@1239,3F4UU@33958,4HC1K@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family PGHMIELC_02305 220668.lp_3240 0.0 1240.7 Lactobacillaceae treB 2.7.1.193,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K02808,ko:K02809,ko:K02810 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00267,M00268,M00269,M00270,M00271,M00272,M00303,M00806 R00811,R02738,R02780,R04111,R04394,R05132,R05199,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system PGHMIELC_02306 220668.lp_3241 3.9e-127 460.7 Lactobacillaceae magIII ko:K07457 ko00000 Bacteria 1V4SG@1239,3F62T@33958,4HI5U@91061,COG2231@1,COG2231@2 NA|NA|NA L Base excision DNA repair protein, HhH-GPD family PGHMIELC_02307 941770.GL622182_gene1271 1.4e-08 65.5 Lactobacillaceae Bacteria 1U6VB@1239,2BBKG@1,3254B@2,3F8JF@33958,4IGP7@91061 NA|NA|NA PGHMIELC_02308 220668.lp_3244 8.2e-69 266.2 Lactobacillaceae ko:K19784 ko00000 Bacteria 1TPRA@1239,3F5W1@33958,4HDA5@91061,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase PGHMIELC_02309 220668.lp_3244 1.7e-21 107.8 Lactobacillaceae ko:K19784 ko00000 Bacteria 1TPRA@1239,3F5W1@33958,4HDA5@91061,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase PGHMIELC_02310 220668.lp_3245 7.9e-238 829.3 Lactobacillaceae Bacteria 1TS0H@1239,3F4R0@33958,4HKK4@91061,COG4908@1,COG4908@2 NA|NA|NA S module of peptide synthetase PGHMIELC_02311 220668.lp_3246 4.2e-104 384.0 Lactobacillaceae Bacteria 1U67Y@1239,29P7B@1,30A5E@2,3F79U@33958,4IFYN@91061 NA|NA|NA PGHMIELC_02312 220668.lp_3247 9.8e-88 329.3 Lactobacillaceae perR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K03711,ko:K09825 ko00000,ko03000 Bacteria 1V400@1239,3F67J@33958,4HHF8@91061,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family PGHMIELC_02313 220668.lp_3248 7.1e-59 233.0 Lactobacillaceae Bacteria 1VXH6@1239,2F7TF@1,3407K@2,3F6UJ@33958,4HXTR@91061 NA|NA|NA S Enterocin A Immunity PGHMIELC_02314 220668.lp_3250 5.4e-36 156.4 Lactobacillaceae Bacteria 1W2PI@1239,295K7@1,2ZSXP@2,3F7SN@33958,4I1YK@91061 NA|NA|NA S Phospholipase_D-nuclease N-terminal PGHMIELC_02315 220668.lp_3251 1.8e-169 601.7 Lactobacillaceae cpdA GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006198,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0008199,GO:0008663,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009187,GO:0009214,GO:0009259,GO:0009261,GO:0009405,GO:0009987,GO:0016043,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042301,GO:0042545,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0045229,GO:0046058,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051704,GO:0055086,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 2.1.2.2,3.1.4.17,3.1.4.53 ko:K01120,ko:K03651,ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,ko02025,map00230,map00670,map01100,map01110,map01130,map02025 M00048 R00191,R01234,R04325,R04326 RC00026,RC00197,RC00296,RC01128 ko00000,ko00001,ko00002,ko01000 Bacteria 1VJ4D@1239,3FC18@33958,4HNZU@91061,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase PGHMIELC_02316 220668.lp_3252 3.8e-104 384.0 Lactobacillaceae Bacteria 1VC3X@1239,3F5IW@33958,4HKVZ@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain PGHMIELC_02317 220668.lp_3254 5.1e-64 250.4 Lactobacillaceae lrgA GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0008565,GO:0009056,GO:0009057,GO:0009253,GO:0015031,GO:0015833,GO:0016020,GO:0030203,GO:0033036,GO:0042886,GO:0043170,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 ko:K05338,ko:K06518 ko02020,map02020 ko00000,ko00001,ko02000 1.E.14.1,1.E.14.2 Bacteria 1VIGA@1239,3F6PC@33958,4HN5Z@91061,COG1380@1,COG1380@2 NA|NA|NA S LrgA family PGHMIELC_02318 220668.lp_3255 7.3e-127 459.9 Lactobacillaceae lrgB ko:K05339 ko02020,map02020 ko00000,ko00001 Bacteria 1TRGN@1239,3F4A8@33958,4HE2Y@91061,COG1346@1,COG1346@2 NA|NA|NA M LrgB-like family PGHMIELC_02319 220668.lp_3256 2.5e-145 521.5 Lactobacillaceae DegV Bacteria 1TRZ4@1239,3F4CW@33958,4HBR8@91061,COG1307@1,COG1307@2 NA|NA|NA S EDD domain protein, DegV family PGHMIELC_02320 220668.lp_3257 4.1e-25 119.8 Lactobacillaceae Bacteria 1U74D@1239,29PW6@1,30AUH@2,3F8YM@33958,4IGZ0@91061 NA|NA|NA PGHMIELC_02321 220668.lp_3259 3.5e-118 431.0 Lactobacillaceae yugP ko:K06973 ko00000 Bacteria 1TPD3@1239,3F4E2@33958,4HB8Z@91061,COG2738@1,COG2738@2 NA|NA|NA S Putative neutral zinc metallopeptidase PGHMIELC_02322 220668.lp_3262 1.1e-294 1018.5 Lactobacillaceae crtI 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 Bacteria 1TV0D@1239,3F62G@33958,4IFA0@91061,COG1233@1,COG1233@2 NA|NA|NA Q Flavin containing amine oxidoreductase PGHMIELC_02323 220668.lp_3263 7.4e-166 589.7 Lactobacillaceae crtB GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.21,2.5.1.32,2.5.1.99 ko:K00801,ko:K02291 ko00100,ko00906,ko00909,ko01062,ko01100,ko01110,ko01130,map00100,map00906,map00909,map01062,map01100,map01110,map01130 M00097 R00702,R02065,R02872,R04218,R06223,R07270,R10177 RC00362,RC00796,RC01101,RC02839,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1TQHF@1239,3F8JK@33958,4HA1A@91061,COG1562@1,COG1562@2 NA|NA|NA I Squalene/phytoene synthase PGHMIELC_02324 220668.lp_3265 1.7e-184 651.7 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TQYU@1239,3F43H@33958,4HC4H@91061,COG1073@1,COG1073@2 NA|NA|NA D Alpha beta PGHMIELC_02325 220668.lp_3266 7.1e-198 696.4 Lactobacillaceae glxK 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 R08572 RC00002,RC00428 ko00000,ko00001,ko01000 Bacteria 1TPSI@1239,3F3V2@33958,4HA91@91061,COG1929@1,COG1929@2 NA|NA|NA G Belongs to the glycerate kinase type-1 family PGHMIELC_02326 220668.lp_3267 8.1e-257 892.5 Lactobacillaceae gor 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1TS0Z@1239,3F3K2@33958,4HBYB@91061,COG1249@1,COG1249@2 NA|NA|NA C Glutathione reductase PGHMIELC_02327 220668.lp_3268 3.4e-55 220.7 Lactobacillaceae Bacteria 1U6SH@1239,29PMI@1,30AJQ@2,3F8ET@33958,4IGK1@91061 NA|NA|NA S Enterocin A Immunity PGHMIELC_02328 220668.lp_3269 7.4e-247 859.4 Lactobacillaceae purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1095 Bacteria 1TPMM@1239,3F48P@33958,4HACW@91061,COG0015@1,COG0015@2 NA|NA|NA F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily PGHMIELC_02329 220668.lp_3270 1.4e-253 881.7 Lactobacillaceae purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ4C@1239,3F3RQ@33958,4H9YT@91061,COG0104@1,COG0104@2 NA|NA|NA F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP PGHMIELC_02330 220668.lp_3271 3.5e-185 654.1 Lactobacillaceae guaC 1.1.1.205,1.7.1.7 ko:K00088,ko:K00364 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R01134,R08240 RC00143,RC00457,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iSB619.SA_RS06660 Bacteria 1TNYF@1239,3F45K@33958,4HA55@91061,COG0516@1,COG0516@2 NA|NA|NA F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides PGHMIELC_02331 220668.lp_3272 1.7e-145 521.9 Lactobacillaceae ptp2 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1V851@1239,3F5K6@33958,4HVA8@91061,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family PGHMIELC_02332 220668.lp_3273 4.8e-279 966.5 Lactobacillaceae cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPKY@1239,3F3SF@33958,4H9TI@91061,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol PGHMIELC_02334 220668.lp_3275 6.2e-82 310.1 Lactobacillaceae Bacteria 1U7SB@1239,29QAF@1,30B9K@2,3FA3T@33958,4IHPP@91061 NA|NA|NA PGHMIELC_02335 220668.lp_3278 1.5e-256 891.7 Lactobacillaceae yhdG ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3F592@33958,4HA66@91061,COG0531@1,COG0531@2 NA|NA|NA E C-terminus of AA_permease PGHMIELC_02337 220668.lp_3279 0.0 1330.1 Lactobacillaceae kup GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 ko:K03549 ko00000,ko02000 2.A.72 Bacteria 1TRUQ@1239,3F4CU@33958,4HA8Z@91061,COG3158@1,COG3158@2 NA|NA|NA P Transport of potassium into the cell PGHMIELC_02338 220668.lp_3280 4.6e-166 590.5 Bacilli Bacteria 1TSGY@1239,4H9WP@91061,COG0053@1,COG0053@2 NA|NA|NA P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family PGHMIELC_02339 220668.lp_3281 9e-179 632.9 Lactobacillaceae Bacteria 1TSBK@1239,3F46E@33958,4HBYJ@91061,COG0628@1,COG0628@2 NA|NA|NA K AI-2E family transporter PGHMIELC_02340 220668.lp_3283 4e-217 760.4 Lactobacillaceae yxjG 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPDQ@1239,3F49P@33958,4HADW@91061,COG0620@1,COG0620@2 NA|NA|NA E methionine synthase, vitamin-B12 independent PGHMIELC_02341 60520.HR47_05270 4.4e-59 233.8 Firmicutes qacC ko:K03297,ko:K11741,ko:K11815 M00710 ko00000,ko00002,ko02000 2.A.7.1,2.A.7.1.6 Bacteria 1VH7F@1239,COG2076@1,COG2076@2 NA|NA|NA P Small Multidrug Resistance protein PGHMIELC_02342 220668.lp_3285 1.1e-44 185.7 Lactobacillaceae qacH ko:K03297 ko00000,ko02000 2.A.7.1 Bacteria 1U651@1239,3F72F@33958,4IFUS@91061,COG2076@1,COG2076@2 NA|NA|NA U Small Multidrug Resistance protein PGHMIELC_02343 220668.lp_3286 3e-116 424.5 Lactobacillaceae hly ko:K11068 ko00000,ko02042 Bacteria 1TSFK@1239,3F578@33958,4HAT2@91061,COG1272@1,COG1272@2 NA|NA|NA S protein, hemolysin III PGHMIELC_02344 220668.lp_3287 5.1e-54 216.9 Lactobacillaceae nmtR GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090 ko:K21886,ko:K21903,ko:K22298 ko00000,ko03000 Bacteria 1VA6G@1239,3F72A@33958,4HKYT@91061,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor PGHMIELC_02345 220668.lp_3288 2.7e-160 571.2 Lactobacillaceae czcD ko:K16264 ko00000,ko02000 2.A.4.1 Bacteria 1TR92@1239,3F4KJ@33958,4HBCQ@91061,COG1230@1,COG1230@2 NA|NA|NA P cation diffusion facilitator family transporter PGHMIELC_02346 220668.lp_3290 2.7e-103 381.3 Lactobacillaceae Bacteria 1VK84@1239,3FBTS@33958,4ISVZ@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins PGHMIELC_02348 220668.lp_3292 2.1e-21 107.5 Lactobacillaceae Bacteria 1U8G6@1239,2BTZR@1,32P89@2,3FAY5@33958,4IIDZ@91061 NA|NA|NA PGHMIELC_02350 220668.lp_3293 6.5e-96 356.7 Lactobacillaceae tag 3.2.2.20 ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1VVUW@1239,3F5KH@33958,4HW42@91061,COG2818@1,COG2818@2 NA|NA|NA L glycosylase PGHMIELC_02351 220668.lp_3294 1.2e-213 748.8 Lactobacillaceae folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796,ko:K18824,ko:K18974 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1TPKT@1239,3F4SS@33958,4H9SY@91061,COG0294@1,COG0294@2 NA|NA|NA H dihydropteroate synthase PGHMIELC_02352 220668.lp_3295 1.7e-105 388.7 Lactobacillaceae xtp 2.5.1.15,3.6.1.66 ko:K00796,ko:K02428 ko00230,ko00790,ko01100,map00230,map00790,map01100 M00126,M00841 R00426,R00720,R01855,R02100,R02720,R03066,R03067,R03531 RC00002,RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 Bacteria 1VWAB@1239,3F4R5@33958,4HWPY@91061,COG0127@1,COG0127@2 NA|NA|NA F Ham1 family PGHMIELC_02353 220668.lp_3296 4.8e-249 866.7 Lactobacillaceae folC 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPX5@1239,3F3ZR@33958,4HBJM@91061,COG0285@1,COG0285@2 NA|NA|NA H Belongs to the folylpolyglutamate synthase family PGHMIELC_02354 220668.lp_3297 2.6e-103 381.3 Lactobacillaceae folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R03503,R04639,R05046,R05048 RC00002,RC00017,RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv3609c Bacteria 1TRNM@1239,3F4A0@33958,4HAXS@91061,COG0302@1,COG0302@2 NA|NA|NA F GTP cyclohydrolase 1 PGHMIELC_02355 220668.lp_3298 2.8e-93 347.8 Lactobacillaceae folK 1.13.11.81,2.5.1.15,2.7.6.3,3.5.4.16,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01495,ko:K01633,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841,M00842,M00843 R00428,R03066,R03067,R03503,R03504,R04639,R05046,R05048,R11037,R11073 RC00002,RC00017,RC00121,RC00263,RC00294,RC00323,RC00721,RC00842,RC00943,RC00945,RC01188,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6PR@1239,3F6SY@33958,4HIMG@91061,COG0801@1,COG0801@2 NA|NA|NA H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) PGHMIELC_02356 220668.lp_3299 2.2e-63 248.1 Lactobacillaceae folB 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01633,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503,R03504,R11037,R11073 RC00002,RC00017,RC00121,RC00721,RC00842,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 1VA0I@1239,3F7N6@33958,4HKKK@91061,COG1539@1,COG1539@2 NA|NA|NA H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin PGHMIELC_02357 220668.lp_3301 4.7e-83 313.9 Lactobacillaceae cvpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 ko:K03558 ko00000 Bacteria 1V7U0@1239,3F643@33958,4HIUU@91061,COG1286@1,COG1286@2 NA|NA|NA S Colicin V production protein PGHMIELC_02358 220668.lp_3302 7.5e-169 599.7 Lactobacillaceae znuA ko:K02077 M00244 ko00000,ko00002,ko02000 3.A.1.15 Bacteria 1V110@1239,3FC74@33958,4HE71@91061,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family PGHMIELC_02359 220668.lp_3303 8.6e-249 865.9 Lactobacillaceae Bacteria 1TS0Y@1239,3F4GE@33958,4HEMR@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_02361 220668.lp_3305 7e-40 169.5 Lactobacillaceae Bacteria 1U6Y5@1239,2DKSV@1,30APG@2,3F8PU@33958,4IGSB@91061 NA|NA|NA PGHMIELC_02362 220668.lp_3310 6.2e-96 356.7 Lactobacillaceae Bacteria 1VKIA@1239,3F86G@33958,4HNUJ@91061,COG4767@1,COG4767@2 NA|NA|NA V VanZ like family PGHMIELC_02363 220668.lp_3312 5e-195 686.8 Lactobacillaceae blaA6 Bacteria 1U828@1239,3F4K3@33958,4HA0Q@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase PGHMIELC_02364 220668.lp_3313 0.0 1531.5 Lactobacillaceae pflB 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 Bacteria 1TPTF@1239,3F53K@33958,4H9RD@91061,COG1882@1,COG1882@2 NA|NA|NA C Pyruvate formate lyase-like PGHMIELC_02365 220668.lp_3314 2.5e-160 571.2 Lactobacillaceae pflA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0018307,GO:0019538,GO:0033554,GO:0036211,GO:0043170,GO:0043364,GO:0043365,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070283,GO:0071704,GO:1901564 1.97.1.4 ko:K04069 R04710 ko00000,ko01000 iECOK1_1307.ECOK1_0925,iEcE24377_1341.EcE24377A_0980,iEcSMS35_1347.EcSMS35_2219,iYL1228.KPN_00930 Bacteria 1TPK2@1239,3F472@33958,4HACV@91061,COG1180@1,COG1180@2 NA|NA|NA C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine PGHMIELC_02366 220668.lp_3316 5.1e-53 213.4 Lactobacillaceae yitW ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1TVP9@1239,3F793@33958,4I3SB@91061,COG2151@1,COG2151@2 NA|NA|NA S Pfam:DUF59 PGHMIELC_02367 220668.lp_3318 7.7e-174 616.3 Lactobacillaceae Bacteria 1TQ12@1239,3F4U1@33958,4HA57@91061,COG4989@1,COG4989@2 NA|NA|NA S Aldo keto reductase PGHMIELC_02368 220668.lp_3319 2.9e-30 137.1 Lactobacillaceae Bacteria 1V7FG@1239,3F6Q4@33958,4HIUY@91061,COG0537@1,COG0537@2 NA|NA|NA FG HIT domain PGHMIELC_02369 220668.lp_3319 1.5e-55 221.9 Lactobacillaceae Bacteria 1V7FG@1239,3F6Q4@33958,4HIUY@91061,COG0537@1,COG0537@2 NA|NA|NA FG HIT domain PGHMIELC_02370 220668.lp_3321 8.1e-38 162.5 Lactobacillaceae Bacteria 1U6UF@1239,3F8I5@33958,4IGN9@91061,COG4430@1,COG4430@2 NA|NA|NA S Bacteriocin-protection, YdeI or OmpD-Associated PGHMIELC_02371 220668.lp_3322 1.4e-77 295.4 Lactobacillaceae Bacteria 1VXE5@1239,2F6G8@1,33YZB@2,3F67Q@33958,4HWYE@91061 NA|NA|NA PGHMIELC_02372 220668.lp_3323 9e-121 439.5 Lactobacillaceae Bacteria 1VIW7@1239,3F7KA@33958,4IPPM@91061,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase family PGHMIELC_02373 220668.lp_3324 1.1e-306 1058.5 Lactobacillaceae ko:K03451 ko00000 2.A.15 Bacteria 1TRS6@1239,3F53Q@33958,4HA7U@91061,COG1292@1,COG1292@2 NA|NA|NA U Belongs to the BCCT transporter (TC 2.A.15) family PGHMIELC_02374 220668.lp_3327 0.0 1115.9 Lactobacillaceae cadA Bacteria 1TQ07@1239,3F4JI@33958,4H9SP@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase PGHMIELC_02376 220668.lp_3330 1.3e-122 445.7 Lactobacillaceae yyaQ Bacteria 1VCQP@1239,3FBDE@33958,4IPPK@91061,COG2315@1,COG2315@2 NA|NA|NA S YjbR PGHMIELC_02377 220668.lp_3333 2.4e-220 771.2 Lactobacillaceae Bacteria 1VK4A@1239,2EM25@1,33ERN@2,3F53P@33958,4HRGD@91061 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2325) PGHMIELC_02378 220668.lp_3334 0.0 1106.7 Lactobacillaceae ade GO:0000034,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005506,GO:0006040,GO:0006044,GO:0006046,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008448,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016787,GO:0016810,GO:0016811,GO:0016814,GO:0018130,GO:0019213,GO:0019239,GO:0019438,GO:0019439,GO:0030145,GO:0034641,GO:0042221,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046348,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055086,GO:0055114,GO:0070887,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0097237,GO:0098754,GO:0098869,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1990748 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 R01244 RC00477 ko00000,ko00001,ko01000 iECUMN_1333.ECUMN_4192,iSFV_1184.SFV_3844,iYO844.BSU14520 Bacteria 1TP84@1239,3F4BJ@33958,4HBB2@91061,COG1001@1,COG1001@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family PGHMIELC_02379 220668.lp_3335 1.3e-199 702.2 Lactobacillaceae frlB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016829,GO:0016835,GO:0016836,GO:0042802 ko:K10708,ko:K19510 R08125 RC00053,RC01805 ko00000,ko01000 iSFV_1184.SFV_3377,iSFxv_1172.SFxv_3701 Bacteria 1UI5E@1239,3F5JC@33958,4ISEC@91061,COG2222@1,COG2222@2 NA|NA|NA M SIS domain PGHMIELC_02380 60520.HR47_01360 6.1e-27 126.7 Lactobacillaceae 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 1U857@1239,3FAJF@33958,4II2Q@91061,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family PGHMIELC_02381 220668.lp_3338 1.2e-255 888.6 Lactobacillaceae nhaC ko:K03315 ko00000,ko02000 2.A.35 Bacteria 1TQ3B@1239,3FB8Z@33958,4HCYW@91061,COG1757@1,COG1757@2 NA|NA|NA C Na H antiporter NhaC PGHMIELC_02382 220668.lp_3339 2.4e-251 874.4 Lactobacillaceae cycA GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease PGHMIELC_02383 220668.lp_3341 2.3e-167 594.7 Lactobacillaceae Bacteria 1V910@1239,3F5GH@33958,4HF90@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF915) PGHMIELC_02384 220668.lp_3342 7.3e-86 323.2 Lactobacillaceae pgpA 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 R02029 RC00017 ko00000,ko00001,ko01000 Bacteria 1V3I0@1239,3F6QT@33958,4HH4Y@91061,COG1267@1,COG1267@2 NA|NA|NA I Phosphatidylglycerophosphatase A PGHMIELC_02385 220668.lp_3343 4.8e-162 577.0 Lactobacillaceae azoB Bacteria 1UY7W@1239,3F4M7@33958,4HDIS@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family PGHMIELC_02386 220668.lp_3344 1.6e-65 255.4 Lactobacillaceae ko:K22296 ko00000,ko03000 Bacteria 1VQ9C@1239,3F887@33958,4HSIB@91061,COG1846@1,COG1846@2 NA|NA|NA K Winged helix DNA-binding domain PGHMIELC_02387 220668.lp_3345 2e-70 271.6 Lactobacillaceae spx4 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1V3QC@1239,3F67K@33958,4HH0I@91061,COG1393@1,COG1393@2 NA|NA|NA P ArsC family PGHMIELC_02388 220668.lp_3346 1.7e-66 258.5 Lactobacillaceae yeaO Bacteria 1VABH@1239,3F715@33958,4HKI2@91061,COG3189@1,COG3189@2 NA|NA|NA S Protein of unknown function, DUF488 PGHMIELC_02389 220668.lp_3348 4e-53 213.8 Lactobacillaceae Bacteria 1W3JF@1239,298U1@1,2ZVY8@2,3F7JE@33958,4I1SS@91061 NA|NA|NA PGHMIELC_02390 220668.lp_3349 4.1e-214 750.4 Lactobacillaceae mutY ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPUT@1239,3FCD0@33958,4H9UM@91061,COG1194@1,COG1194@2 NA|NA|NA L A G-specific adenine glycosylase PGHMIELC_02391 220668.lp_3350 1.9e-62 245.0 Lactobacillaceae Bacteria 1UQDP@1239,2BQC3@1,32J76@2,3F6GE@33958,4IFH8@91061 NA|NA|NA PGHMIELC_02392 220668.lp_3351 3.1e-84 317.8 Bacilli Bacteria 1UIQW@1239,2AJ3X@1,319NA@2,4ISQT@91061 NA|NA|NA PGHMIELC_02393 220668.lp_3352 3.4e-79 300.8 Lactobacillaceae hsp3 ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 1VG0E@1239,3F4EY@33958,4HPDH@91061,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family PGHMIELC_02394 220668.lp_3353 2e-55 221.5 Lactobacillaceae Bacteria 1U684@1239,2A4XX@1,30TJQ@2,3F7A6@33958,4IFYV@91061 NA|NA|NA PGHMIELC_02395 1136177.KCA1_2738 2.1e-14 84.0 Lactobacillaceae Bacteria 1U74I@1239,29PWB@1,30AUN@2,3F8YT@33958,4IGZ5@91061 NA|NA|NA PGHMIELC_02396 220668.lp_3355 1.1e-115 422.5 Lactobacillaceae Bacteria 1UJSC@1239,3F4ZZ@33958,4HCVT@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family PGHMIELC_02397 220668.lp_3356 1.3e-81 308.9 Lactobacillaceae elaA GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 ko:K02348 ko00000 Bacteria 1VAJY@1239,3F5B8@33958,4HIH7@91061,COG2153@1,COG2153@2 NA|NA|NA S GNAT family PGHMIELC_02398 220668.lp_3358 1.6e-158 565.5 Lactobacillaceae Bacteria 1TR6G@1239,3F423@33958,4HAMD@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family PGHMIELC_02399 220668.lp_3359 1.8e-119 435.3 Lactobacillaceae Bacteria 1V26W@1239,3F3TU@33958,4HGMW@91061,COG1814@1,COG1814@2 NA|NA|NA S membrane PGHMIELC_02400 220668.lp_3360 6.8e-111 406.8 Lactobacillaceae Bacteria 1V3A2@1239,3F53V@33958,4HFSI@91061,COG1814@1,COG1814@2 NA|NA|NA S VIT family PGHMIELC_02401 220668.lp_3362 1.3e-190 672.2 Lactobacillaceae pva2 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 1TPZS@1239,3FB8X@33958,4HMSI@91061,COG3049@1,COG3049@2 NA|NA|NA M Linear amide C-N hydrolases, choloylglycine hydrolase family PGHMIELC_02402 220668.lp_3363 0.0 1257.7 Lactobacillaceae copB 3.6.3.4 ko:K01533 R00086 RC00002 ko00000,ko01000 3.A.3.5 Bacteria 1TP5S@1239,3F4IX@33958,4HAI0@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase PGHMIELC_02403 220668.lp_3365 9.4e-74 282.7 Lactobacillaceae copR Bacteria 1VA7Q@1239,3F7D0@33958,4HKGF@91061,COG3682@1,COG3682@2 NA|NA|NA K Copper transport repressor CopY TcrY PGHMIELC_02404 220668.lp_3366 7.4e-40 169.5 Lactobacillaceae Bacteria 1U6GI@1239,29PEA@1,30ACG@2,3F7VJ@33958,4IG8Q@91061 NA|NA|NA PGHMIELC_02405 220668.lp_3367 3.5e-73 280.8 Lactobacillaceae Bacteria 1VEMD@1239,3F68X@33958,4HNMT@91061,COG4416@1,COG4416@2 NA|NA|NA S COG NOG18757 non supervised orthologous group PGHMIELC_02406 60520.HR47_01240 4.1e-246 857.1 Lactobacillaceae lmrB ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1TPRN@1239,3F4A2@33958,4H9VV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_02407 220668.lp_3371 3.4e-25 120.2 Lactobacillaceae Bacteria 1U76D@1239,29PXN@1,30AW1@2,3F917@33958,4IH14@91061 NA|NA|NA PGHMIELC_02408 220668.lp_3372 1.1e-49 202.2 Lactobacillaceae Bacteria 1U67G@1239,29P6Y@1,30A51@2,3F790@33958,4IFXZ@91061 NA|NA|NA PGHMIELC_02409 220668.lp_3373 9.4e-65 252.7 Lactobacillaceae ycgX Bacteria 1U5TC@1239,3F6GH@33958,4IFH9@91061,COG5562@1,COG5562@2 NA|NA|NA S Protein of unknown function (DUF1398) PGHMIELC_02410 220668.lp_3374 6.8e-251 872.8 Lactobacillaceae Bacteria 1TTBN@1239,3F4YG@33958,4HA3B@91061,COG1457@1,COG1457@2 NA|NA|NA U Belongs to the purine-cytosine permease (2.A.39) family PGHMIELC_02411 220668.lp_3392 5.9e-214 750.0 Lactobacillaceae mdtG GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085 ko:K08161 ko00000,ko02000 2.A.1.2.20 Bacteria 1TRDJ@1239,3F3T5@33958,4H9Q9@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_02412 220668.lp_3393 2e-180 638.3 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TQYU@1239,3F43H@33958,4HC4H@91061,COG1073@1,COG1073@2 NA|NA|NA D Alpha beta PGHMIELC_02413 220668.lp_3394 3.1e-78 297.7 Lactobacillaceae M1-874 ko:K13638,ko:K13640 ko00000,ko03000 Bacteria 1U5VW@1239,3F6KX@33958,4IFJP@91061,COG0789@1,COG0789@2 NA|NA|NA K Domain of unknown function (DUF1836) PGHMIELC_02414 220668.lp_3397 4.5e-85 320.5 Lactobacillaceae 2.4.2.6 ko:K08728 ko00240,map00240 R02806 RC00063 ko00000,ko00001,ko01000 Bacteria 1V70Q@1239,3FBQG@33958,4IRXR@91061,COG3613@1,COG3613@2 NA|NA|NA F Nucleoside 2-deoxyribosyltransferase PGHMIELC_02415 220668.lp_3398 0.0 1600.1 Lactobacillaceae pacL3 3.6.3.8 ko:K01537 ko00000,ko01000 3.A.3.2 Bacteria 1TPF5@1239,3F588@33958,4H9S5@91061,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus PGHMIELC_02416 220668.lp_3400 1.1e-310 1071.6 Lactobacillaceae cpdB 3.1.3.6,3.1.4.16 ko:K01119 ko00230,ko00240,map00230,map00240 R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135 RC00078,RC00296 ko00000,ko00001,ko01000 Bacteria 1TPV2@1239,3F45U@33958,4HC2M@91061,COG0737@1,COG0737@2 NA|NA|NA F Belongs to the 5'-nucleotidase family PGHMIELC_02417 220668.lp_3402 3.8e-152 544.3 Lactobacillaceae ywkB ko:K07088 ko00000 Bacteria 1VDS9@1239,3F5JF@33958,4HQT5@91061,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein PGHMIELC_02418 220668.lp_3403 5.2e-164 583.6 Lactobacillaceae yvgN Bacteria 1TPM1@1239,3F3PW@33958,4HARE@91061,COG0656@1,COG0656@2 NA|NA|NA C Aldo keto reductase PGHMIELC_02419 220668.lp_3404 9.2e-133 479.6 Lactobacillaceae thrE Bacteria 1TSE8@1239,3F4XE@33958,4HBW1@91061,COG2966@1,COG2966@2 NA|NA|NA S Putative threonine/serine exporter PGHMIELC_02420 220668.lp_3405 2e-77 295.0 Lactobacillaceae Bacteria 1V6P0@1239,3F63I@33958,4HJ1Y@91061,COG3610@1,COG3610@2 NA|NA|NA S Threonine/Serine exporter, ThrE PGHMIELC_02421 1136177.KCA1_2769 2.3e-43 181.4 Lactobacillaceae Bacteria 1W5K5@1239,28ZBI@1,2ZM3D@2,3F825@33958,4I1Q6@91061 NA|NA|NA S Protein of unknown function (DUF1093) PGHMIELC_02422 220668.lp_3407 1.1e-147 529.3 Lactobacillaceae uppP GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031224,GO:0031226,GO:0042221,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050380,GO:0050896,GO:0071944 3.6.1.27 ko:K06153 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 iYL1228.KPN_03461 Bacteria 1TPFA@1239,3F510@33958,4HB0M@91061,COG1968@1,COG1968@2 NA|NA|NA V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin PGHMIELC_02423 220668.lp_3408 2.7e-91 341.3 Lactobacillaceae ymdB Bacteria 1TPCU@1239,3F6GV@33958,4HIHC@91061,COG2110@1,COG2110@2 NA|NA|NA S Macro domain protein PGHMIELC_02424 220668.lp_3409 1.7e-94 352.1 Lactobacillaceae ko:K16137,ko:K22041 ko00000,ko03000 Bacteria 1U5JB@1239,3F62U@33958,4IFA6@91061,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator PGHMIELC_02425 220668.lp_3410 5.5e-50 203.4 Lactobacillaceae yvlA Bacteria 1VIUB@1239,2DZIG@1,32VBI@2,3F7EN@33958,4HRZP@91061 NA|NA|NA PGHMIELC_02426 220668.lp_3411 1e-160 572.8 Lactobacillaceae ypuA Bacteria 1UY79@1239,3F416@33958,4HAZ5@91061,COG4086@1,COG4086@2 NA|NA|NA S Protein of unknown function (DUF1002) PGHMIELC_02427 220668.lp_3412 0.0 1855.1 Lactobacillaceae Bacteria 1U730@1239,29PV7@1,30ATD@2,3F8WR@33958,4IGXI@91061 NA|NA|NA PGHMIELC_02428 220668.lp_3413 2.2e-185 654.8 Lactobacillaceae Bacteria 1U7FS@1239,3F9JU@33958,4IHBT@91061,COG4072@1,COG4072@2 NA|NA|NA S Bacterial protein of unknown function (DUF916) PGHMIELC_02429 220668.lp_3414 1.7e-129 468.8 Lactobacillaceae Bacteria 1U7CM@1239,29Q22@1,30B0N@2,3F9D0@33958,4IH81@91061 NA|NA|NA S WxL domain surface cell wall-binding PGHMIELC_02430 220668.lp_3415 1.5e-135 488.8 Bacilli ko:K07506 ko00000,ko03000 Bacteria 1TSKR@1239,4H9R5@91061,COG2207@1,COG2207@2 NA|NA|NA T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain PGHMIELC_02431 220668.lp_3416 1.2e-88 332.4 Lactobacillaceae Bacteria 1U5DI@1239,3F5NB@33958,4IF50@91061,COG1846@1,COG1846@2 NA|NA|NA K Winged helix DNA-binding domain PGHMIELC_02432 220668.lp_3417 2.4e-116 424.9 Lactobacillaceae luxT Bacteria 1VZKY@1239,3F43G@33958,4HM1C@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family PGHMIELC_02433 220668.lp_3418 0.0 1127.9 Lactobacillaceae pckA 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPXB@1239,3F4N4@33958,4IS6N@91061,COG1866@1,COG1866@2 NA|NA|NA H Phosphoenolpyruvate carboxykinase PGHMIELC_02434 220668.lp_3419 1.8e-27 127.9 Bacilli Bacteria 1W51D@1239,29A0B@1,2ZX1X@2,4I0QW@91061 NA|NA|NA PGHMIELC_02435 220668.lp_3420 9.6e-285 985.3 Lactobacillaceae gadB 4.1.1.15 ko:K01580 ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940 M00027 R00261,R00489,R01682,R02466 RC00299 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv3432c Bacteria 1TPVX@1239,3F45J@33958,4HENF@91061,COG0076@1,COG0076@2 NA|NA|NA E Belongs to the group II decarboxylase family PGHMIELC_02436 220668.lp_3421 1.5e-75 290.0 Lactobacillaceae mltD ko:K08307,ko:K12204,ko:K19224,ko:K21471 ko00000,ko01000,ko01002,ko01011,ko02044 3.A.7.10.1,3.A.7.9.1 CBM50 Bacteria 1VFKC@1239,3F6HG@33958,4IFHN@91061,COG0791@1,COG0791@2,COG1388@1,COG1388@2 NA|NA|NA M PFAM NLP P60 protein PGHMIELC_02437 220668.lp_3422 2.5e-53 214.5 Lactobacillaceae Bacteria 1U693@1239,29P87@1,30A69@2,3F7C5@33958,4IG08@91061 NA|NA|NA PGHMIELC_02438 220668.lp_3423 4.2e-62 243.8 Lactobacillaceae Bacteria 1U6DW@1239,2A5X0@1,30UP0@2,3F7P8@33958,4IG5K@91061 NA|NA|NA PGHMIELC_02440 1449338.JQLU01000003_gene673 8.6e-13 80.1 Bacilli Bacteria 1VYIN@1239,2FFJB@1,347GT@2,4HZ4E@91061 NA|NA|NA PGHMIELC_02441 1136177.KCA1_2783 2.8e-65 255.0 Lactobacillaceae XK27_09885 Bacteria 1VKIA@1239,3F83R@33958,4HR6Q@91061,COG4767@1,COG4767@2 NA|NA|NA V VanZ like family PGHMIELC_02443 1266845.Q783_00390 1.3e-11 76.3 Carnobacteriaceae Bacteria 1VEKB@1239,27GXE@186828,4HPGP@91061,COG1476@1,COG1476@2 NA|NA|NA K Cro/C1-type HTH DNA-binding domain PGHMIELC_02444 220668.lp_3425 9.5e-109 399.4 Lactobacillaceae Bacteria 1V7JI@1239,2APNY@1,31ESI@2,3F6EE@33958,4HVID@91061 NA|NA|NA PGHMIELC_02445 220668.lp_3426 1.3e-53 215.3 Lactobacillaceae Bacteria 1VGC1@1239,3F89N@33958,4HQJ6@91061,COG4367@1,COG4367@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2316) PGHMIELC_02446 220668.lp_3427 1.3e-161 575.9 Lactobacillaceae 4.1.1.46 ko:K07045,ko:K14333 ko00362,ko00627,ko01120,map00362,map00627,map01120 R00821 RC00390 ko00000,ko00001,ko01000 Bacteria 1UXYD@1239,3FB98@33958,4HDAD@91061,COG2159@1,COG2159@2 NA|NA|NA S Amidohydrolase PGHMIELC_02447 220668.lp_3429 9e-104 382.9 Lactobacillaceae Bacteria 1U5IB@1239,3F60H@33958,4IF91@91061,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator PGHMIELC_02448 220668.lp_3430 4.2e-183 647.1 Lactobacillaceae yfeX ko:K07223 ko00000 Bacteria 1UY9Y@1239,3F45Z@33958,4HACQ@91061,COG2837@1,COG2837@2 NA|NA|NA P Peroxidase PGHMIELC_02449 220668.lp_3431 1.3e-136 492.3 Lactobacillaceae menG GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQEA@1239,3F3R2@33958,4HAR9@91061,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) PGHMIELC_02450 220668.lp_3432 2.6e-129 468.0 Lactobacillaceae ydcF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 Bacteria 1TS1Q@1239,3F62V@33958,4I32T@91061,COG1434@1,COG1434@2 NA|NA|NA S Gram-negative-bacterium-type cell wall biogenesis PGHMIELC_02451 220668.lp_3433 2.3e-184 651.4 Lactobacillaceae celE GO:0000272,GO:0001871,GO:0003674,GO:0003824,GO:0004553,GO:0005488,GO:0005975,GO:0005976,GO:0006073,GO:0006080,GO:0008150,GO:0008152,GO:0008810,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010391,GO:0010410,GO:0016052,GO:0016787,GO:0016788,GO:0016798,GO:0017144,GO:0030243,GO:0030245,GO:0030246,GO:0030247,GO:0030248,GO:0042737,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0045491,GO:0045493,GO:0046555,GO:0051273,GO:0051275,GO:0052689,GO:0071554,GO:0071704,GO:1901575,GO:2000884 3.2.1.4 ko:K01179,ko:K20276 ko00500,ko01100,ko02024,map00500,map01100,map02024 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 1TSSA@1239,3FBDC@33958,4IPPG@91061,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase family PGHMIELC_02452 220668.lp_3435 0.0 1171.8 Lactobacillaceae cadA 3.6.3.3,3.6.3.5 ko:K01534 ko00000,ko01000 3.A.3.6 Bacteria 1TQ07@1239,3F4T3@33958,4H9SP@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase PGHMIELC_02453 220668.lp_3436 6.3e-142 510.0 Lactobacillaceae glpF ko:K02440 ko00000,ko02000 1.A.8.1,1.A.8.2 Bacteria 1TP4T@1239,3F4J6@33958,4HAWP@91061,COG0580@1,COG0580@2 NA|NA|NA U Belongs to the MIP aquaporin (TC 1.A.8) family PGHMIELC_02454 1423734.JCM14202_2812 9.5e-55 219.2 Lactobacillaceae txlA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 iAPECO1_1312.trxA Bacteria 1UI60@1239,3F6Q0@33958,4ISEX@91061,COG0526@1,COG0526@2 NA|NA|NA O Thioredoxin-like domain PGHMIELC_02455 1423734.JCM14202_2813 5.6e-40 169.9 Lactobacillaceae yrkD Bacteria 1VFB9@1239,3F74Z@33958,4HNVQ@91061,COG1937@1,COG1937@2 NA|NA|NA S Metal-sensitive transcriptional repressor PGHMIELC_02456 220668.lp_3440 1.6e-18 98.2 Lactobacillaceae Bacteria 1U6GC@1239,29PE2@1,30AC8@2,3F7V0@33958,4IG8G@91061 NA|NA|NA PGHMIELC_02457 60520.HR47_11380 1.2e-94 352.4 Lactobacillaceae dps ko:K04047 ko00000,ko03036 Bacteria 1VB1X@1239,3F4SN@33958,4HMJG@91061,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family PGHMIELC_02458 220668.lp_3442 1.6e-32 144.8 Lactobacillaceae copZ ko:K07213 ko04978,map04978 ko00000,ko00001 Bacteria 1VFJ8@1239,3F830@33958,4HNY2@91061,COG2608@1,COG2608@2 NA|NA|NA P Heavy-metal-associated domain PGHMIELC_02459 220668.lp_3444 3.3e-118 431.0 Lactobacillaceae 4.1.99.16,4.2.3.22,4.2.3.75 ko:K10187,ko:K21562 ko00909,ko01100,ko01110,map00909,map01100,map01110 R07647,R07648,R08543,R09487 RC01832,RC02159,RC02160,RC02183,RC02425,RC02552 ko00000,ko00001,ko01000,ko03000 Bacteria 1V3XW@1239,3F4YM@33958,4HDG1@91061,COG0664@1,COG0664@2 NA|NA|NA K Transcriptional regulator, Crp Fnr family PGHMIELC_02460 220668.lp_3445 0.0 1305.0 Lactobacillaceae pepO 3.4.24.71 ko:K01415,ko:K07386 ko00000,ko01000,ko01002,ko04147 Bacteria 1TQTA@1239,3F4CX@33958,4HDSF@91061,COG3590@1,COG3590@2 NA|NA|NA O Peptidase family M13 PGHMIELC_02461 220668.lp_3448 1.9e-83 315.1 Lactobacillaceae yoaA 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 1VCN3@1239,3F7GP@33958,4HKNF@91061,COG1670@1,COG1670@2 NA|NA|NA J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins PGHMIELC_02462 220668.lp_3449 1.3e-262 911.8 Lactobacillaceae nox Bacteria 1TPWW@1239,3F449@33958,4H9U7@91061,COG0446@1,COG0446@2 NA|NA|NA C NADH oxidase PGHMIELC_02463 220668.lp_3450 0.0 1384.8 Lactobacillaceae XK27_00720 ko:K13730 ko05100,map05100 ko00000,ko00001 Bacteria 1UI5Z@1239,3F46F@33958,4ISEW@91061,COG4886@1,COG4886@2 NA|NA|NA S Leucine-rich repeat (LRR) protein PGHMIELC_02464 220668.lp_3451 6.1e-164 583.6 Lactobacillaceae Bacteria 1VCXS@1239,3F5HA@33958,4HKJG@91061,COG4072@1,COG4072@2 NA|NA|NA S Cell surface protein PGHMIELC_02465 220668.lp_3452 1.5e-118 432.2 Lactobacillaceae Bacteria 1U57C@1239,29WH0@1,30I33@2,3F511@33958,4IEYT@91061 NA|NA|NA S WxL domain surface cell wall-binding PGHMIELC_02466 220668.lp_3453 2.3e-99 368.2 Lactobacillaceae Bacteria 1U6PS@1239,2BV09@1,32QCV@2,3F89M@33958,4IGGR@91061 NA|NA|NA S WxL domain surface cell wall-binding PGHMIELC_02467 220668.lp_3454 1e-44 185.7 Lactobacillaceae Bacteria 1U6D2@1239,29PBC@1,30A9J@2,3F7N0@33958,4IG4U@91061 NA|NA|NA PGHMIELC_02468 220668.lp_3458 1.2e-103 382.5 Lactobacillaceae ko:K16137 ko00000,ko03000 Bacteria 1US3R@1239,3F53A@33958,4HCGK@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family PGHMIELC_02469 220668.lp_3459 1.5e-49 201.8 Lactobacillaceae Bacteria 1W3TC@1239,2DDHT@1,2ZI5S@2,3F7A3@33958,4IFYT@91061 NA|NA|NA PGHMIELC_02470 220668.lp_3460 2.2e-246 857.8 Lactobacillaceae Bacteria 1VE6N@1239,3F556@33958,4HMSF@91061,COG3864@1,COG3864@2 NA|NA|NA S Putative metallopeptidase domain PGHMIELC_02471 220668.lp_3461 2.4e-220 771.2 Lactobacillaceae 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1U8NZ@1239,3F53Z@33958,4HCYD@91061,COG0714@1,COG0714@2 NA|NA|NA S associated with various cellular activities PGHMIELC_02472 1136177.KCA1_2814 1.8e-108 398.7 Lactobacillaceae aqpZ GO:0003674,GO:0005215,GO:0005372,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006833,GO:0006884,GO:0006950,GO:0006970,GO:0008150,GO:0008361,GO:0009628,GO:0009987,GO:0009992,GO:0015250,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042044,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0050896,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 ko:K02440,ko:K06188 ko00000,ko02000 1.A.8,1.A.8.1,1.A.8.2 iJN678.apqZ Bacteria 1UZX3@1239,3F4K9@33958,4HA8I@91061,COG0580@1,COG0580@2 NA|NA|NA U Belongs to the MIP aquaporin (TC 1.A.8) family PGHMIELC_02473 220668.lp_3464 0.0 1151.7 Lactobacillaceae ubiB ko:K03688 ko00000 Bacteria 1TPIV@1239,3F51C@33958,4HBW3@91061,COG0661@1,COG0661@2 NA|NA|NA S ABC1 family PGHMIELC_02474 220668.lp_3466 6.9e-251 872.8 Lactobacillaceae brnQ GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 ko:K03311 ko00000 2.A.26 Bacteria 1TQIS@1239,3F3KC@33958,4HAKA@91061,COG1114@1,COG1114@2 NA|NA|NA U Component of the transport system for branched-chain amino acids PGHMIELC_02475 220668.lp_3468 0.0 1215.7 Lactobacillaceae lacS ko:K03292,ko:K11104,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.1,2.A.2.2 Bacteria 1TRA5@1239,3F3P7@33958,4HCDS@91061,COG2190@1,COG2190@2,COG2211@1,COG2211@2 NA|NA|NA G Transporter PGHMIELC_02476 220668.lp_3469 0.0 1422.1 Lactobacillaceae lacA 3.2.1.23 ko:K12308 ko00052,map00052 R01105 RC00452 ko00000,ko00001,ko01000 Bacteria 1TQN6@1239,3F3PC@33958,4HARI@91061,COG1874@1,COG1874@2 NA|NA|NA G -beta-galactosidase PGHMIELC_02477 220668.lp_3470 1.6e-188 665.2 Lactobacillaceae lacR ko:K02529 ko00000,ko03000 Bacteria 1TPZJ@1239,3F3PB@33958,4HC9Z@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator PGHMIELC_02478 220668.lp_3471 0.0 1364.0 Lactobacillaceae 3.2.1.40 ko:K05989 ko00000,ko01000 Bacteria 1UZDK@1239,3FB7C@33958,4HF3P@91061,COG3408@1,COG3408@2 NA|NA|NA G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain PGHMIELC_02479 220668.lp_3472 1.6e-230 805.1 Lactobacillaceae mdtH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06610,ko:K08162 ko00000,ko02000 2.A.1.1.27,2.A.1.2.21 Bacteria 1VSI3@1239,3F5X2@33958,4HTHH@91061,COG0477@1,COG0477@2 NA|NA|NA P Sugar (and other) transporter PGHMIELC_02480 220668.lp_3473 7.9e-304 1048.9 Lactobacillaceae ram2 3.2.1.40 ko:K05989 ko00000,ko01000 Bacteria 1TSSU@1239,3F4PD@33958,4HCTS@91061,COG3408@1,COG3408@2 NA|NA|NA G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain PGHMIELC_02481 220668.lp_3474 8.6e-232 809.3 Lactobacillaceae ko:K06610 ko00000,ko02000 2.A.1.1.27 Bacteria 1TRBM@1239,3F56N@33958,4HDZU@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_02482 220668.lp_3476 7.4e-183 646.4 Lactobacillaceae rhaR Bacteria 1V23T@1239,3FBDX@33958,4IPPZ@91061,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein PGHMIELC_02483 220668.lp_3477 5.1e-110 403.7 Lactobacillaceae fic ko:K04095 ko00000,ko03036 Bacteria 1TPUZ@1239,3FBK2@33958,4HIQT@91061,COG2184@1,COG2184@2 NA|NA|NA D Fic/DOC family PGHMIELC_02484 220668.lp_3478 1.6e-76 292.0 Lactobacillaceae ko:K07726 ko00000,ko03000 Bacteria 1U5RA@1239,3F6CZ@33958,4IFFC@91061,COG2944@1,COG2944@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins PGHMIELC_02485 220668.lp_3479 3.3e-152 544.3 Lactobacillaceae galR ko:K02529 ko00000,ko03000 Bacteria 1TPZJ@1239,3F3PB@33958,4HC9Z@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator PGHMIELC_02486 220668.lp_3479 2.6e-07 60.1 Lactobacillaceae galR ko:K02529 ko00000,ko03000 Bacteria 1TPZJ@1239,3F3PB@33958,4HC9Z@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator PGHMIELC_02487 220668.lp_3480 1.3e-284 984.9 Lactobacillaceae galT 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPBN@1239,3F4D8@33958,4HAYJ@91061,COG4468@1,COG4468@2 NA|NA|NA G UDP-glucose--hexose-1-phosphate uridylyltransferase PGHMIELC_02488 220668.lp_3481 3.1e-192 677.6 Lactobacillaceae galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ7N@1239,3F3YF@33958,4H9U5@91061,COG1087@1,COG1087@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family PGHMIELC_02489 220668.lp_3482 9.3e-225 785.8 Lactobacillaceae galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TPD0@1239,3F3Q9@33958,4HARP@91061,COG0153@1,COG0153@2 NA|NA|NA F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) PGHMIELC_02490 220668.lp_3483 0.0 1322.8 Lactobacillaceae lacL 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 Bacteria 1TPDC@1239,3F4EI@33958,4HANW@91061,COG3250@1,COG3250@2 NA|NA|NA G Belongs to the glycosyl hydrolase 2 family PGHMIELC_02491 220668.lp_3484 8.3e-187 659.4 Lactobacillaceae lacM 3.2.1.23,3.2.1.35,3.2.1.51,3.2.1.97 ko:K01190,ko:K01197,ko:K01206,ko:K17624 ko00052,ko00511,ko00531,ko00600,ko01100,map00052,map00511,map00531,map00600,map01100 M00076,M00077 R01105,R01678,R03355,R04783,R06114,R07824,R07825,R10905 RC00049,RC00452 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042,ko04147 GH101,GH29 Bacteria 1TRVA@1239,3F51Z@33958,4HFMH@91061,COG3250@1,COG3250@2 NA|NA|NA G beta-galactosidase PGHMIELC_02492 220668.lp_3485 0.0 1506.1 Lactobacillaceae rafA 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 Bacteria 1TQF4@1239,3F3RU@33958,4HA5R@91061,COG3345@1,COG3345@2 NA|NA|NA G alpha-galactosidase PGHMIELC_02493 220668.lp_3486 0.0 1212.2 Lactobacillaceae lacS GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03292,ko:K11104,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.1,2.A.2.2 Bacteria 1TRA5@1239,3F3P7@33958,4HCDS@91061,COG2190@1,COG2190@2,COG2211@1,COG2211@2 NA|NA|NA G Transporter PGHMIELC_02494 220668.lp_3487 4.1e-200 703.7 Lactobacillaceae galM 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 1V5UK@1239,3FC7G@33958,4HTRY@91061,COG2017@1,COG2017@2 NA|NA|NA G Catalyzes the interconversion of alpha and beta anomers of maltose PGHMIELC_02495 220668.lp_3488 1.1e-173 615.9 Lactobacillaceae galR ko:K02529 ko00000,ko03000 Bacteria 1TPZJ@1239,3F3PB@33958,4HC9Z@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator PGHMIELC_02496 220668.lp_3489 2.6e-194 684.5 Lactobacillaceae ko:K19265 ko00000,ko01000 Bacteria 1TRS0@1239,3F414@33958,4HAZ2@91061,COG0667@1,COG0667@2 NA|NA|NA C Aldo keto reductase family protein PGHMIELC_02497 220668.lp_3490 2.4e-65 254.6 Lactobacillaceae GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 Bacteria 1VGE7@1239,3F6YB@33958,4HNE7@91061,COG3576@1,COG3576@2 NA|NA|NA S pyridoxamine 5-phosphate PGHMIELC_02498 220668.lp_3491 0.0 1511.1 Lactobacillaceae 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 1TTD3@1239,3F5DN@33958,4HT4K@91061,COG0431@1,COG0431@2,COG1053@1,COG1053@2 NA|NA|NA C FAD binding domain PGHMIELC_02499 220668.lp_3492 8.2e-179 632.9 Lactobacillaceae apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 1TR9C@1239,3F5ID@33958,4HHVC@91061,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein PGHMIELC_02500 60520.HR47_11135 1.9e-130 471.9 Lactobacillaceae aroD GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25,4.2.1.10 ko:K03785,ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413,R03084 RC00206,RC00848 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSPN@1239,3F4TX@33958,4HDMG@91061,COG0710@1,COG0710@2 NA|NA|NA E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate PGHMIELC_02501 60520.HR47_11130 1.2e-214 752.3 Lactobacillaceae ydiM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015291,GO:0015292,GO:0016020,GO:0022804,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 Bacteria 1UI3V@1239,3FBSK@33958,4HBYF@91061,COG2271@1,COG2271@2 NA|NA|NA G Transporter PGHMIELC_02502 60520.HR47_11125 4.2e-169 600.5 Lactobacillaceae aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0030266,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0052734,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25,1.1.1.282,1.3.5.4 ko:K00014,ko:K00244,ko:K05887 ko00020,ko00190,ko00400,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko02020,map00020,map00190,map00400,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map01230,map02020 M00009,M00011,M00022,M00150,M00173 R01872,R02164,R02413,R06846,R06847 RC00045,RC00154,RC00206 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS14185,iSFxv_1172.SFxv_1929,iS_1188.S1854 Bacteria 1TQRY@1239,3F4WM@33958,4HD4R@91061,COG0169@1,COG0169@2 NA|NA|NA E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) PGHMIELC_02503 60520.HR47_11120 3.4e-163 580.9 Lactobacillaceae Bacteria 1TRVX@1239,3F48I@33958,4HFSV@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator, LysR family PGHMIELC_02504 60520.HR47_11115 6.7e-210 736.5 Lactobacillaceae ydiN GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015291,GO:0015292,GO:0016020,GO:0022804,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 Bacteria 1UI3V@1239,3F3ZF@33958,4ISEV@91061,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily PGHMIELC_02505 220668.lp_3504 7.6e-64 249.6 Lactobacillaceae Bacteria 1U62A@1239,2C4GV@1,30A1B@2,3F6V4@33958,4IFRA@91061 NA|NA|NA PGHMIELC_02506 220668.lp_3505 1.8e-155 555.1 Lactobacillaceae estA Bacteria 1TPA9@1239,3F3ZG@33958,4IPXU@91061,COG0627@1,COG0627@2 NA|NA|NA S Putative esterase PGHMIELC_02507 220668.lp_3506 1.2e-134 485.7 Lactobacillaceae ko:K03710 ko00000,ko03000 Bacteria 1VCJ9@1239,3F6DC@33958,4HM7V@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA domain PGHMIELC_02508 220668.lp_3507 2.4e-248 864.4 Lactobacillaceae pts29C ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 Bacteria 1TP8D@1239,3F54Z@33958,4H9W2@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane PGHMIELC_02509 220668.lp_3508 3e-165 587.8 Lactobacillaceae murQ 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 R08555 RC00397,RC00746 ko00000,ko00001,ko01000 Bacteria 1TPSF@1239,3F4T1@33958,4HBWP@91061,COG2103@1,COG2103@2 NA|NA|NA G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate PGHMIELC_02510 220668.lp_3509 1.9e-161 575.1 Lactobacillaceae 2.7.1.59 ko:K00884 ko00520,ko01100,map00520,map01100 R01201 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1V38W@1239,3F5MG@33958,4HGPI@91061,COG2971@1,COG2971@2 NA|NA|NA G BadF/BadG/BcrA/BcrD ATPase family PGHMIELC_02511 220668.lp_3510 1.7e-212 745.0 Lactobacillaceae ko:K09963 ko00000 Bacteria 1TRIY@1239,3F4FK@33958,4H9V2@91061,COG3589@1,COG3589@2 NA|NA|NA S Bacterial protein of unknown function (DUF871) PGHMIELC_02512 220668.lp_3512 1e-292 1011.9 Lactobacillaceae bglH 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family PGHMIELC_02513 220668.lp_3513 0.0 1156.4 Lactobacillaceae pts30BCA 2.7.1.193,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02802,ko:K02803,ko:K02804,ko:K02808,ko:K02809,ko:K02810 ko00500,ko00520,ko02060,map00500,map00520,map02060 M00267,M00269,M00271 R00811,R05199 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system PGHMIELC_02514 220668.lp_3514 1.3e-154 552.4 Lactobacillaceae licT ko:K02538,ko:K03488 ko00000,ko03000 Bacteria 1TT5A@1239,3F4SJ@33958,4HC5Y@91061,COG3711@1,COG3711@2 NA|NA|NA K CAT RNA binding domain PGHMIELC_02515 220668.lp_3525 3.4e-293 1013.4 Lactobacillaceae bglH 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family PGHMIELC_02516 220668.lp_3526 9.4e-291 1005.4 Lactobacillaceae pbg10 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family PGHMIELC_02517 220668.lp_3527 0.0 1271.9 Lactobacillaceae bglP 2.7.1.193,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02802,ko:K02803,ko:K02804,ko:K02808,ko:K02809,ko:K02810 ko00500,ko00520,ko02060,map00500,map00520,map02060 M00267,M00269,M00271 R00811,R05199 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system PGHMIELC_02518 220668.lp_3529 2.5e-158 564.7 Lactobacillaceae licT ko:K02538,ko:K03488 ko00000,ko03000 Bacteria 1TT5A@1239,3F4SJ@33958,4HC5Y@91061,COG3711@1,COG3711@2 NA|NA|NA K CAT RNA binding domain PGHMIELC_02519 220668.lp_3530 0.0 1475.7 Lactobacillaceae treP 2.4.1.64 ko:K05342 ko00500,ko01100,map00500,map01100 R02727 RC00049 ko00000,ko00001,ko01000 GH65 Bacteria 1TQMB@1239,3F3PG@33958,4HAVB@91061,COG1554@1,COG1554@2 NA|NA|NA G hydrolase, family 65, central catalytic PGHMIELC_02520 220668.lp_3531 2.1e-174 618.2 Lactobacillaceae ko:K02529 ko00000,ko03000 Bacteria 1TRFH@1239,3F5CG@33958,4HBNT@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family PGHMIELC_02521 220668.lp_3533 1.5e-269 934.9 Lactobacillaceae ko:K16211 ko00000,ko02000 2.A.2.6 Bacteria 1TRP7@1239,3F3YZ@33958,4HCUK@91061,COG2211@1,COG2211@2 NA|NA|NA G Major Facilitator PGHMIELC_02522 220668.lp_3534 0.0 1612.8 Lactobacillaceae malZ 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 GH31 Bacteria 1TR8N@1239,3F4CE@33958,4HB1D@91061,COG1501@1,COG1501@2 NA|NA|NA G Belongs to the glycosyl hydrolase 31 family PGHMIELC_02524 220668.lp_3536 2.9e-187 661.0 Lactobacillaceae cbh 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 1TPZS@1239,3F4NH@33958,4HC4Y@91061,COG3049@1,COG3049@2 NA|NA|NA M Linear amide C-N hydrolase, choloylglycine hydrolase family protein PGHMIELC_02525 220668.lp_3537 1.3e-145 522.3 Lactobacillaceae yxeH Bacteria 1TR16@1239,3F55S@33958,4HCZ6@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase PGHMIELC_02526 220668.lp_3538 0.0 1333.9 Lactobacillaceae tkt 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPIB@1239,3F4IJ@33958,4HADA@91061,COG0021@1,COG0021@2 NA|NA|NA H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate PGHMIELC_02527 220668.lp_3539 7e-113 413.3 Lactobacillaceae tal 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4Q@1239,3F3X3@33958,4HA8G@91061,COG0176@1,COG0176@2 NA|NA|NA F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway PGHMIELC_02528 220668.lp_3540 6.4e-241 839.7 Lactobacillaceae ulaA 2.7.1.194 ko:K02822,ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 Bacteria 1TQK5@1239,3F4Y4@33958,4HBAD@91061,COG3037@1,COG3037@2 NA|NA|NA S PTS system sugar-specific permease component PGHMIELC_02529 220668.lp_3541 6.3e-45 186.4 Lactobacillaceae ulaB 2.7.1.194,2.7.1.200 ko:K02774,ko:K02822,ko:K03475 ko00052,ko00053,ko01100,ko01120,ko02060,map00052,map00053,map01100,map01120,map02060 M00279,M00283,M00550 R05570,R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1,4.A.7.1 Bacteria 1VBT2@1239,3F7EB@33958,4HMYC@91061,COG3414@1,COG3414@2 NA|NA|NA G Phosphotransferase system galactitol-specific IIB component PGHMIELC_02530 220668.lp_3542 6.7e-78 296.6 Lactobacillaceae 2.7.1.194,2.7.1.200,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02821,ko:K11201 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00306,M00550 R03232,R05570,R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.5.1,4.A.7.1 Bacteria 1V42N@1239,3FBDV@33958,4HP6Y@91061,COG1762@1,COG1762@2 NA|NA|NA G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 PGHMIELC_02531 220668.lp_3543 0.0 1352.0 Lactobacillaceae 2.7.1.194,2.7.1.200,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02821,ko:K03483,ko:K11201 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00306,M00550 R03232,R05570,R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5.1,4.A.7.1 Bacteria 1TQT1@1239,3F5NN@33958,4H9N4@91061,COG1762@1,COG1762@2,COG3711@1,COG3711@2 NA|NA|NA G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 PGHMIELC_02532 220668.lp_3544 1.3e-113 415.6 Lactobacillaceae gph 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1V7U6@1239,3F6YJ@33958,4HJ9I@91061,COG0546@1,COG0546@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase PGHMIELC_02533 220668.lp_3545 3e-188 664.5 Lactobacillaceae gutB 1.1.1.1,1.1.1.14 ko:K00001,ko:K00008 ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 M00014 R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPWP@1239,3F3WG@33958,4HABC@91061,COG1063@1,COG1063@2 NA|NA|NA C Zinc-binding dehydrogenase PGHMIELC_02534 220668.lp_3546 1.1e-231 808.9 Lactobacillaceae gatC ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 Bacteria 1TQ10@1239,3F427@33958,4HA1Q@91061,COG3775@1,COG3775@2 NA|NA|NA G PTS system sugar-specific permease component PGHMIELC_02535 220668.lp_3547 1.1e-44 185.7 Lactobacillaceae 2.7.1.194,2.7.1.200 ko:K02774,ko:K02822 ko00052,ko00053,ko01100,ko01120,ko02060,map00052,map00053,map01100,map01120,map02060 M00279,M00283,M00550 R05570,R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1,4.A.7.1 Bacteria 1VA2P@1239,3FBN7@33958,4IR9V@91061,COG3414@1,COG3414@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit PGHMIELC_02536 220668.lp_3548 8.1e-79 299.7 Lactobacillaceae 2.7.1.194,2.7.1.200,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02821,ko:K11201 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00306,M00550 R03232,R05570,R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.5.1,4.A.7.1 Bacteria 1V8H9@1239,3F4A7@33958,4HK36@91061,COG1762@1,COG1762@2 NA|NA|NA G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 PGHMIELC_02537 60520.HR47_10915 5.2e-123 447.2 Lactobacillaceae ko:K02444 ko00000,ko03000 Bacteria 1UXYW@1239,3F68Z@33958,4IQMP@91061,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain PGHMIELC_02538 220668.lp_3551 0.0 1650.2 Lactobacillaceae xfp 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 Bacteria 1TR23@1239,3F3TZ@33958,4HC2J@91061,COG3957@1,COG3957@2 NA|NA|NA G Phosphoketolase PGHMIELC_02539 220668.lp_3552 1.5e-49 201.8 Bacteria yueI Bacteria COG5506@1,COG5506@2 NA|NA|NA S Protein of unknown function (DUF1694) PGHMIELC_02540 220668.lp_3552 8.1e-10 68.2 Bacteria yueI Bacteria COG5506@1,COG5506@2 NA|NA|NA S Protein of unknown function (DUF1694) PGHMIELC_02541 220668.lp_3553 9.6e-103 379.4 Lactobacillaceae maa 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 ko00000,ko01000 Bacteria 1TQEX@1239,3F5U8@33958,4HAJ0@91061,COG0110@1,COG0110@2 NA|NA|NA S Maltose O-acetyltransferase PGHMIELC_02542 220668.lp_3554 1.3e-265 921.8 Lactobacillaceae araA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.3.1.4 ko:K01804 ko00040,ko01100,map00040,map01100 R01761 RC00516 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_1922,iB21_1397.B21_00063,iBWG_1329.BWG_0058,iE2348C_1286.E2348C_0063,iECBD_1354.ECBD_3555,iECD_1391.ECD_00064,iECED1_1282.ECED1_0061,iECIAI1_1343.ECIAI1_0062,iECNA114_1301.ECNA114_0050,iECO103_1326.ECO103_0063,iECO26_1355.ECO26_0064,iECOK1_1307.ECOK1_0061,iECP_1309.ECP_0063,iECS88_1305.ECS88_0065,iECSE_1348.ECSE_0062,iECW_1372.ECW_m0060,iEKO11_1354.EKO11_3852,iEcE24377_1341.EcE24377A_0064,iEcHS_1320.EcHS_A0066,iEcSMS35_1347.EcSMS35_0064,iEcolC_1368.EcolC_3595,iLF82_1304.LF82_0105,iLJ478.TM0276,iNRG857_1313.NRG857_00320,iSBO_1134.SBO_0049,iSSON_1240.SSON_0068,iUMN146_1321.UM146_23095,iUTI89_1310.UTI89_C0067,iWFL_1372.ECW_m0060 Bacteria 1TPXC@1239,3F4PN@33958,4HAWS@91061,COG2160@1,COG2160@2 NA|NA|NA G Catalyzes the conversion of L-arabinose to L-ribulose PGHMIELC_02543 220668.lp_3555 1e-136 492.7 Lactobacillaceae araD 4.1.2.17,4.1.2.19,5.1.3.4 ko:K01628,ko:K01629,ko:K03077 ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120 M00550 R01785,R02262,R02263,R05850 RC00438,RC00599,RC00603,RC00604,RC01479 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS00590 Bacteria 1TPDV@1239,3F43P@33958,4H9W0@91061,COG0235@1,COG0235@2 NA|NA|NA G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source PGHMIELC_02544 220668.lp_3556 1.9e-305 1054.3 Lactobacillaceae araB 2.7.1.12,2.7.1.16,2.7.1.5 ko:K00848,ko:K00851,ko:K00853 ko00030,ko00040,ko00051,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map00051,map01100,map01110,map01120,map01130,map01200 R01526,R01737,R01902,R02439,R03014 RC00002,RC00017,RC00538 ko00000,ko00001,ko01000 Bacteria 1TP91@1239,3F4HI@33958,4HBGF@91061,COG1070@1,COG1070@2 NA|NA|NA G carbohydrate kinase FGGY PGHMIELC_02545 220668.lp_3557 5.5e-256 889.8 Lactobacillaceae araP ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 2.A.1.1,2.A.1.1.26 Bacteria 1UHPS@1239,3FBSI@33958,4IS5K@91061,COG0477@1,COG0477@2 NA|NA|NA U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family PGHMIELC_02546 220668.lp_3558 1.4e-206 725.3 Lactobacillaceae araR ko:K02103 ko00000,ko03000 Bacteria 1TP9Q@1239,3F3ZM@33958,4HARD@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator PGHMIELC_02547 220668.lp_3559 7.4e-136 490.0 Lactobacillaceae iSB619.SA_RS01765 Bacteria 1TR5E@1239,3F49F@33958,4HGM0@91061,COG1737@1,COG1737@2 NA|NA|NA K Helix-turn-helix domain, rpiR family PGHMIELC_02548 220668.lp_3560 3.7e-72 277.3 Lactobacillaceae yueI Bacteria 1U7K6@1239,3F9UU@33958,4IHH7@91061,COG5506@1,COG5506@2 NA|NA|NA S Protein of unknown function (DUF1694) PGHMIELC_02549 220668.lp_3561 1.3e-164 585.5 Lactobacillaceae Bacteria 1TP1H@1239,3F43I@33958,4HFZ9@91061,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold PGHMIELC_02550 220668.lp_3562 5.2e-161 573.5 Lactobacillaceae Bacteria 1TP1H@1239,3F43I@33958,4HFZ9@91061,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold PGHMIELC_02551 220668.lp_3563 2.6e-272 944.1 Lactobacillaceae nanT ko:K03307 ko00000 2.A.21 Bacteria 1TQCK@1239,3F50Z@33958,4HB5K@91061,COG0591@1,COG0591@2 NA|NA|NA E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family PGHMIELC_02552 220668.lp_3565 5.2e-207 726.9 Lactobacillaceae napA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 Bacteria 1TS32@1239,3F3QK@33958,4HAGC@91061,COG0475@1,COG0475@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family PGHMIELC_02553 220668.lp_3566 1.9e-135 488.4 Lactobacillaceae kguE 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1VA9Q@1239,3F651@33958,4HJ2W@91061,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase domain protein TIM barrel PGHMIELC_02554 220668.lp_3567 5.2e-156 557.0 Lactobacillaceae nanK Bacteria 1TP04@1239,3F46U@33958,4HGYM@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family PGHMIELC_02555 220668.lp_3568 6.2e-165 586.6 Lactobacillaceae nanA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0006054,GO:0006082,GO:0008150,GO:0008152,GO:0008747,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019262,GO:0019752,GO:0042737,GO:0042802,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046348,GO:0046395,GO:0071704,GO:1901135,GO:1901136,GO:1901575 4.1.3.3,4.3.3.7 ko:K01639,ko:K01714 ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R01811,R10147 RC00159,RC00600,RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 iAF1260.b3225,iAPECO1_1312.APECO1_3218,iB21_1397.B21_03036,iBWG_1329.BWG_2926,iE2348C_1286.E2348C_3497,iEC042_1314.EC042_3509,iEC55989_1330.EC55989_3638,iECABU_c1320.ECABU_c36330,iECBD_1354.ECBD_0522,iECB_1328.ECB_03085,iECDH10B_1368.ECDH10B_3402,iECDH1ME8569_1439.ECDH1ME8569_3113,iECD_1391.ECD_03085,iECH74115_1262.ECH74115_4542,iECIAI1_1343.ECIAI1_3367,iECNA114_1301.ECNA114_3298,iECO103_1326.ECO103_3966,iECO26_1355.ECO26_4324,iECOK1_1307.ECOK1_3639,iECP_1309.ECP_3308,iECS88_1305.ECS88_3602,iECSF_1327.ECSF_3050,iECSP_1301.ECSP_4194,iECUMN_1333.ECUMN_3699,iECs_1301.ECs4098,iETEC_1333.ETEC_3486,iEcDH1_1363.EcDH1_0481,iEcE24377_1341.EcE24377A_3707,iEcHS_1320.EcHS_A3413,iEcolC_1368.EcolC_0481,iG2583_1286.G2583_3945,iJO1366.b3225,iJR904.b3225,iSDY_1059.SDY_3400,iSFV_1184.SFV_3250,iSF_1195.SF3261,iSFxv_1172.SFxv_3573,iSSON_1240.SSON_3366,iS_1188.S3478,iSbBS512_1146.SbBS512_E3551,iUMN146_1321.UM146_00280,iUTI89_1310.UTI89_C3655,iY75_1357.Y75_RS16725,iZ_1308.Z4583 Bacteria 1TQRK@1239,3F4KH@33958,4HCJ9@91061,COG0329@1,COG0329@2 NA|NA|NA EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate PGHMIELC_02556 220668.lp_3571 1.1e-121 442.6 Lactobacillaceae nanE 5.1.3.9 ko:K01788 ko00520,map00520 R02087 RC00290 ko00000,ko00001,ko01000 Bacteria 1TSR7@1239,3F529@33958,4HBPF@91061,COG3010@1,COG3010@2 NA|NA|NA G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) PGHMIELC_02557 220668.lp_3572 4.9e-229 800.0 Lactobacillaceae 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 Bacteria 1TRNN@1239,3F60G@33958,4HE8X@91061,COG0446@1,COG0446@2 NA|NA|NA S Pyridine nucleotide-disulphide oxidoreductase PGHMIELC_02558 220668.lp_3573 4.2e-70 270.4 Lactobacillaceae Bacteria 1V717@1239,2AK1X@1,31ARI@2,3F6WW@33958,4HIQ9@91061 NA|NA|NA S Pyrimidine dimer DNA glycosylase PGHMIELC_02559 220668.lp_3575 4.5e-89 334.0 Lactobacillaceae folT 2.7.13.3 ko:K02478,ko:K07704 ko02020,map02020 M00492 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1VB87@1239,3FBSH@33958,4ISET@91061,COG3275@1,COG3275@2 NA|NA|NA T ECF transporter, substrate-specific component PGHMIELC_02560 1229758.C270_04340 3.6e-11 73.2 Leuconostocaceae Bacteria 1W25C@1239,292I6@1,2ZQ2A@2,4AYA1@81850,4I09I@91061 NA|NA|NA PGHMIELC_02561 220668.lp_3577 9e-13 79.3 Lactobacillaceae ytgB Bacteria 1VENK@1239,3F7EK@33958,4HNKV@91061,COG2261@1,COG2261@2 NA|NA|NA S Transglycosylase associated protein PGHMIELC_02562 220668.lp_3578 3.9e-175 620.5 Lactobacillaceae katA GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1990748 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPPV@1239,3F5CW@33958,4H9XQ@91061,COG0753@1,COG0753@2 NA|NA|NA C Belongs to the catalase family PGHMIELC_02563 220668.lp_3578 1.1e-95 355.9 Lactobacillaceae katA GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1990748 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPPV@1239,3F5CW@33958,4H9XQ@91061,COG0753@1,COG0753@2 NA|NA|NA C Belongs to the catalase family PGHMIELC_02564 220668.lp_3579 1.9e-77 295.0 Lactobacillaceae yneH 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1V3QC@1239,3F9GQ@33958,4HH0I@91061,COG1393@1,COG1393@2 NA|NA|NA K ArsC family PGHMIELC_02565 220668.lp_3580 2.8e-134 484.6 Lactobacillaceae ko:K07707 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko02022 Bacteria 1V392@1239,3F9BM@33958,4HHAI@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain PGHMIELC_02566 60520.HR47_10820 8.7e-160 570.1 Lactobacillaceae 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1V1ET@1239,3F71I@33958,4HGNA@91061,COG3290@1,COG3290@2 NA|NA|NA T GHKL domain PGHMIELC_02567 60520.HR47_10815 1.8e-12 77.4 Lactobacillaceae Bacteria 1U8H3@1239,2BU7S@1,32PH8@2,3FAZ6@33958,4IIEY@91061 NA|NA|NA PGHMIELC_02568 60520.HR47_10810 5.3e-67 260.8 Lactobacillaceae agrB ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 Bacteria 1VKU7@1239,3F9AM@33958,4IH6Z@91061,COG4512@1,COG4512@2 NA|NA|NA KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor PGHMIELC_02569 220668.lp_3583 0.0 1313.5 Lactobacillaceae clpL ko:K04086 ko00000,ko03110 Bacteria 1TRHP@1239,3FC3Z@33958,4HAHZ@91061,COG0542@1,COG0542@2 NA|NA|NA O C-terminal, D2-small domain, of ClpB protein PGHMIELC_02571 220668.lp_3586 6.1e-202 709.9 Lactobacillaceae lctO ko:K10530 ko00000,ko01000 Bacteria 1TPC4@1239,3F3N3@33958,4HAU5@91061,COG1304@1,COG1304@2 NA|NA|NA C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases PGHMIELC_02572 220668.lp_3587 0.0 1154.4 Lactobacillaceae poxB 1.2.3.3,1.2.5.1 ko:K00156,ko:K00158 ko00620,ko01100,map00620,map01100 R00207,R03145 RC00860,RC02745 ko00000,ko00001,ko01000 Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family PGHMIELC_02573 220668.lp_3588 8.7e-72 276.2 Lactobacillaceae Bacteria 1V34F@1239,3F6N2@33958,4IFKN@91061,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator PGHMIELC_02574 220668.lp_3589 0.0 1193.3 Lactobacillaceae spxB 1.2.3.3,1.2.5.1 ko:K00156,ko:K00158 ko00620,ko01100,map00620,map01100 R00207,R03145 RC00860,RC02745 ko00000,ko00001,ko01000 Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family PGHMIELC_02575 220668.lp_3590 1.1e-71 275.8 Bacteria yueI Bacteria COG5506@1,COG5506@2 NA|NA|NA S Protein of unknown function (DUF1694) PGHMIELC_02576 220668.lp_3591 2.5e-83 314.7 Lactobacillaceae Bacteria 1VSZX@1239,3F4ZU@33958,4HTJ1@91061,COG2364@1,COG2364@2 NA|NA|NA S Membrane PGHMIELC_02577 220668.lp_3591 5.8e-31 139.8 Lactobacillaceae Bacteria 1VSZX@1239,3F4ZU@33958,4HTJ1@91061,COG2364@1,COG2364@2 NA|NA|NA S Membrane PGHMIELC_02578 220668.lp_3592 1.2e-165 589.0 Lactobacillaceae rhaD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019321,GO:0019323,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575 4.1.2.17,4.1.2.19,5.1.3.4 ko:K01628,ko:K01629,ko:K03077 ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120 M00550 R01785,R02262,R02263,R05850 RC00438,RC00599,RC00603,RC00604,RC01479 ko00000,ko00001,ko00002,ko01000 Bacteria 1TRMG@1239,3F4WZ@33958,4H9QT@91061,COG0235@1,COG0235@2 NA|NA|NA H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde PGHMIELC_02579 220668.lp_3593 1.3e-256 891.7 Lactobacillaceae rhaA GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008740,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 2.7.1.5,5.3.1.14 ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 R01902,R02437,R03014 RC00002,RC00017,RC00434 ko00000,ko00001,ko01000 Bacteria 1TS42@1239,3F5GK@33958,4HBQP@91061,COG4806@1,COG4806@2 NA|NA|NA G L-rhamnose isomerase (RhaA) PGHMIELC_02580 220668.lp_3594 5e-56 223.4 Lactobacillaceae rhaM GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.1.3.32 ko:K03534 R10819 RC00563 ko00000,ko01000 Bacteria 1VA1C@1239,3F70M@33958,4HM5P@91061,COG3254@1,COG3254@2 NA|NA|NA G Involved in the anomeric conversion of L-rhamnose PGHMIELC_02581 220668.lp_3595 1.8e-286 991.1 Lactobacillaceae rhaB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008993,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019200,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046835,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901575 2.7.1.12,2.7.1.16,2.7.1.5,5.3.1.14 ko:K00848,ko:K00851,ko:K00853,ko:K01813 ko00030,ko00040,ko00051,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map00051,map01100,map01110,map01120,map01130,map01200 R01526,R01737,R01902,R02437,R02439,R03014 RC00002,RC00017,RC00434,RC00538 ko00000,ko00001,ko01000 iEcE24377_1341.EcE24377A_4435 Bacteria 1TP7Z@1239,3F3UM@33958,4HB5X@91061,COG1070@1,COG1070@2 NA|NA|NA F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate PGHMIELC_02582 220668.lp_3596 7.8e-244 849.4 Lactobacillaceae iolF ko:K06610 ko00000,ko02000 2.A.1.1.27 Bacteria 1TRBM@1239,3F5E4@33958,4HE7W@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_02583 220668.lp_3597 1.9e-178 631.7 Lactobacillaceae rhaR Bacteria 1TS6T@1239,3FBEN@33958,4HGX3@91061,COG0662@1,COG0662@2,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein PGHMIELC_02584 220668.lp_3598 1e-139 502.7 Lactobacillaceae ko:K02444 ko00000,ko03000 Bacteria 1UZ6T@1239,3FBHX@33958,4HBKU@91061,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain PGHMIELC_02585 220668.lp_2009 7.6e-42 176.4 Lactobacillaceae Bacteria 1TQ93@1239,3F4RD@33958,4HDNZ@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein PGHMIELC_02586 220668.lp_1064 1.1e-94 352.8 Lactobacillaceae Bacteria 1TQ93@1239,3F4RD@33958,4HDNZ@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein PGHMIELC_02587 585524.HMPREF0493_0553 6.9e-146 523.9 Lactobacillaceae Bacteria 1TP4A@1239,3F40X@33958,4HDAB@91061,COG3547@1,COG3547@2 NA|NA|NA L COG3547 Transposase and inactivated derivatives PGHMIELC_02588 525318.HMPREF0497_2979 5.5e-289 999.6 Lactobacillaceae clcA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006821,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015672,GO:0015698,GO:0015706,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0031404,GO:0034220,GO:0042802,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 ko:K03281,ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4,2.A.49 iAF1260.b0155,iB21_1397.B21_00153,iBWG_1329.BWG_0148,iE2348C_1286.E2348C_0162,iEC042_1314.EC042_0155,iEC55989_1330.EC55989_0149,iECBD_1354.ECBD_3463,iECDH10B_1368.ECDH10B_0135,iECDH1ME8569_1439.ECDH1ME8569_0149,iECD_1391.ECD_00154,iECIAI1_1343.ECIAI1_0153,iECO103_1326.ECO103_0155,iECSE_1348.ECSE_0156,iECUMN_1333.ECUMN_0152,iECW_1372.ECW_m0152,iEKO11_1354.EKO11_3761,iETEC_1333.ETEC_0151,iEcDH1_1363.EcDH1_3447,iEcE24377_1341.EcE24377A_0160,iEcolC_1368.EcolC_3504,iJO1366.b0155,iSSON_1240.SSON_0167,iUMNK88_1353.UMNK88_159,iWFL_1372.ECW_m0152,iY75_1357.Y75_RS00790,iZ_1308.Z0166 Bacteria 1TPX0@1239,3F3MU@33958,4HD2H@91061,COG0038@1,COG0038@2,COG0569@1,COG0569@2 NA|NA|NA P chloride PGHMIELC_02589 543734.LCABL_06250 1.1e-193 682.6 Lactobacillaceae napA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 Bacteria 1TS32@1239,3F3QK@33958,4HAGC@91061,COG0475@1,COG0475@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family PGHMIELC_02590 1114972.AUAW01000027_gene721 9.1e-77 292.7 Lactobacillaceae Bacteria 1U342@1239,3F5GC@33958,4IF2W@91061,COG3293@1,COG3293@2 NA|NA|NA L Transposase DDE domain PGHMIELC_02591 1114972.AUAW01000027_gene722 1.8e-68 265.0 Lactobacillaceae Bacteria 1V7PZ@1239,3FBCS@33958,4I274@91061,COG3293@1,COG3293@2 NA|NA|NA L Putative transposase of IS4/5 family (DUF4096) PGHMIELC_02592 1400520.LFAB_17360 2.1e-160 571.6 Lactobacillaceae ypjC Bacteria 1TR9J@1239,3FC4M@33958,4H9N6@91061,COG1284@1,COG1284@2 NA|NA|NA S Uncharacterised 5xTM membrane BCR, YitT family COG1284 PGHMIELC_02593 1400520.LFAB_17365 4.7e-106 390.6 Lactobacillaceae Bacteria 1UY4S@1239,3FBF8@33958,4HD5D@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain PGHMIELC_02594 1400520.LFAB_17370 2.3e-113 415.2 Lactobacillaceae Bacteria 1TQEG@1239,3F43M@33958,4HD6M@91061,COG2801@1,COG2801@2 NA|NA|NA L hmm pf00665 PGHMIELC_02595 1423807.BACO01000083_gene2410 3e-181 641.0 Lactobacillaceae 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1V0Y9@1239,3F63P@33958,4HC0F@91061,COG0208@1,COG0208@2 NA|NA|NA F Ribonucleotide reductase, small chain PGHMIELC_02596 1400520.LFAB_17380 8e-171 606.3 Lactobacillaceae nrdF 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1TQTH@1239,3F5T7@33958,4H9WX@91061,COG0208@1,COG0208@2 NA|NA|NA F Ribonucleotide reductase, small chain PGHMIELC_02597 1423807.BACO01000083_gene2412 0.0 1448.0 Lactobacillaceae nrdE 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 iYO844.BSU17380 Bacteria 1TPFH@1239,3F3XG@33958,4H9X0@91061,COG0209@1,COG0209@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides PGHMIELC_02598 1400520.LFAB_17390 4.7e-81 307.0 Lactobacillaceae nrdI GO:0000166,GO:0003674,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0019538,GO:0032553,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564 ko:K03647 ko00000 Bacteria 1V764@1239,3F4MF@33958,4HJVP@91061,COG1780@1,COG1780@2 NA|NA|NA F NrdI Flavodoxin like PGHMIELC_02600 1423807.BACO01000083_gene2414 3.4e-61 240.7 Lactobacillaceae ypgQ ko:K06950 ko00000 Bacteria 1V7IZ@1239,3F3PN@33958,4HIVB@91061,COG1418@1,COG1418@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. PGHMIELC_02601 60520.HR47_01140 4e-19 101.3 Lactobacillaceae Bacteria 1U65M@1239,3F74C@33958,4IFVG@91061,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein PGHMIELC_02602 387344.LVIS_1505 2.5e-152 545.8 Lactobacillaceae Bacteria 1U7QR@1239,29Q9F@1,30B8J@2,3FA11@33958,4IHN1@91061 NA|NA|NA PGHMIELC_02603 1423815.BACR01000010_gene654 6.9e-35 154.8 Lactobacillaceae Bacteria 1VCXS@1239,3F5HA@33958,4HKJG@91061,COG4072@1,COG4072@2 NA|NA|NA S Cell surface protein PGHMIELC_02606 1136177.KCA1_0964 2.1e-08 63.9 Lactobacillaceae Bacteria 1V1QC@1239,3F65F@33958,4HH7E@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain PGHMIELC_02607 60520.HR47_10235 2.5e-10 70.9 Lactobacillaceae ko:K07483 ko00000 Bacteria 1V1QC@1239,3F65F@33958,4HH7E@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain PGHMIELC_02608 60520.HR47_01140 5.9e-17 94.0 Lactobacillaceae Bacteria 1U65M@1239,3F74C@33958,4IFVG@91061,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein PGHMIELC_02609 543734.LCABL_03600 7.5e-19 100.5 Lactobacillaceae Bacteria 1TT3P@1239,3F4YY@33958,4I28K@91061,COG3209@1,COG3209@2 NA|NA|NA M Bacterial Ig-like domain (group 3) PGHMIELC_02610 1400520.LFAB_14610 4.3e-09 67.0 Lactobacillaceae 3.4.21.72 ko:K01347 ko00000,ko01000,ko01002,ko02000,ko02044 1.B.12.3 Bacteria 1TT3P@1239,3F4YY@33958,4I28K@91061,COG3209@1,COG3209@2,COG4886@1,COG4886@2 NA|NA|NA M Bacterial Ig-like domain (group 3) PGHMIELC_02611 46256.BBIK01000006_gene1202 2e-07 62.8 Leuconostocaceae Bacteria 1UYD7@1239,4AY8V@81850,4HHUD@91061,COG4886@1,COG4886@2 NA|NA|NA D Mycoplasma protein of unknown function, DUF285 PGHMIELC_02613 220668.lp_1228 1.7e-51 209.5 Lactobacillaceae ko:K07506 ko00000,ko03000 Bacteria 1UIXD@1239,3FBTP@33958,4ISVP@91061,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein PGHMIELC_02614 220668.lp_0216 5.3e-40 170.2 Lactobacillaceae ko:K07487 ko00000 Bacteria 1TQQ9@1239,3F4M8@33958,4H9KK@91061,COG3666@1,COG3666@2 NA|NA|NA L Transposase PGHMIELC_02615 220668.lp_0216 2.4e-22 110.9 Lactobacillaceae ko:K07487 ko00000 Bacteria 1TQQ9@1239,3F4M8@33958,4H9KK@91061,COG3666@1,COG3666@2 NA|NA|NA L Transposase PGHMIELC_02616 220668.lp_0216 8e-18 95.9 Lactobacillaceae ko:K07487 ko00000 Bacteria 1TQQ9@1239,3F4M8@33958,4H9KK@91061,COG3666@1,COG3666@2 NA|NA|NA L Transposase PGHMIELC_02617 543734.LCABL_03600 3.7e-76 293.5 Lactobacillaceae Bacteria 1TT3P@1239,3F4YY@33958,4I28K@91061,COG3209@1,COG3209@2 NA|NA|NA M Bacterial Ig-like domain (group 3) PGHMIELC_02618 220668.lp_3093 2.6e-105 390.2 Lactobacillaceae ko:K07273 ko00000 Bacteria 1V3SH@1239,3F63N@33958,4HNR1@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 PGHMIELC_02619 1138822.PL11_10540 5.4e-74 283.9 Lactobacillaceae uvrX 2.7.7.7 ko:K02346,ko:K03502,ko:K14161 ko00000,ko01000,ko03400 Bacteria 1TP42@1239,3F3WN@33958,4HA1P@91061,COG0389@1,COG0389@2 NA|NA|NA L Belongs to the DNA polymerase type-Y family PGHMIELC_02620 220668.lp_3629 1.9e-285 987.6 Lactobacillaceae bgl 3.2.1.21,3.2.1.86 ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 R00026,R00839,R02558,R02887,R02985,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3FC7B@33958,4H9KU@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family PGHMIELC_02621 220668.lp_3630 3.9e-159 567.4 Lactobacillaceae ypbG 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1UZ80@1239,3FBD4@33958,4HD5J@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family PGHMIELC_02622 220668.lp_3631 0.0 1809.3 Lactobacillaceae mngB 2.3.1.204,3.2.1.170,3.2.1.24 ko:K01191,ko:K15524,ko:K16869 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 GH38 Bacteria 1TQEH@1239,3F4XS@33958,4HBC7@91061,COG0383@1,COG0383@2 NA|NA|NA G Glycosyl hydrolases family 38 N-terminal domain PGHMIELC_02623 220668.lp_3632 3.1e-253 880.6 Lactobacillaceae ko:K09704 ko00000 Bacteria 1TRJI@1239,3F535@33958,4HBQW@91061,COG3538@1,COG3538@2 NA|NA|NA S Metal-independent alpha-mannosidase (GH125) PGHMIELC_02624 220668.lp_3633 1e-193 682.6 Lactobacillaceae rliB ko:K02103 ko00000,ko03000 Bacteria 1TP9Q@1239,3F3ZM@33958,4HARD@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator PGHMIELC_02625 220668.lp_3634 0.0 1495.7 Lactobacillaceae ypdD Bacteria 1TQAG@1239,3F5E5@33958,4HBMP@91061,COG3537@1,COG3537@2 NA|NA|NA G Glycosyl hydrolase family 92 PGHMIELC_02626 220668.lp_3635 5.9e-216 756.5 Lactobacillaceae msmX ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko02000 3.A.1.1 Bacteria 1TP2M@1239,3FC3D@33958,4HAMQ@91061,COG3842@1,COG3842@2 NA|NA|NA P Belongs to the ABC transporter superfamily PGHMIELC_02627 220668.lp_3637 2.1e-165 588.2 Lactobacillaceae scrK 2.7.1.2,2.7.1.4 ko:K00845,ko:K00847 ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R00760,R00867,R01600,R01786,R03920 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQU4@1239,3F3K8@33958,4HA1C@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family PGHMIELC_02628 220668.lp_3638 6.3e-271 939.5 Lactobacillaceae yesN ko:K07720 ko02020,map02020 M00519 ko00000,ko00001,ko00002,ko02022 Bacteria 1TSN6@1239,3F5EJ@33958,4HC7D@91061,COG2207@1,COG2207@2,COG4753@1,COG4753@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein PGHMIELC_02629 220668.lp_3639 0.0 1078.9 Lactobacillaceae yesM 2.7.13.3 ko:K07718 ko02020,map02020 M00519 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TPVR@1239,3FBSJ@33958,4HIS6@91061,COG2972@1,COG2972@2 NA|NA|NA T Histidine kinase PGHMIELC_02630 220668.lp_3640 4.1e-107 394.0 Lactobacillaceae ypcB Bacteria 1VE6A@1239,3F76H@33958,4HMBU@91061,COG5578@1,COG5578@2 NA|NA|NA S integral membrane protein PGHMIELC_02631 220668.lp_3641 0.0 1128.2 Lactobacillaceae dexB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.10,3.2.1.70 ko:K01182,ko:K01215 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13 Bacteria 1TP53@1239,3F41I@33958,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain protein PGHMIELC_02632 220668.lp_3642 2.8e-279 967.2 Lactobacillaceae ko:K17318 ko02010,map02010 M00603 ko00000,ko00001,ko00002,ko02000 3.A.1.1.29,3.A.1.1.9 Bacteria 1TPWV@1239,3F525@33958,4HBPS@91061,COG1653@1,COG1653@2 NA|NA|NA G Domain of unknown function (DUF3502) PGHMIELC_02633 220668.lp_3643 1.3e-160 572.4 Lactobacillaceae lplC ko:K02026,ko:K17320 ko02010,map02010 M00207,M00603 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.29,3.A.1.1.9 Bacteria 1TP1G@1239,3F5SV@33958,4HAID@91061,COG0395@1,COG0395@2 NA|NA|NA U Binding-protein-dependent transport system inner membrane component PGHMIELC_02634 220668.lp_3644 5.2e-181 640.2 Lactobacillaceae ko:K17319 ko02010,map02010 M00603 ko00000,ko00001,ko00002,ko02000 3.A.1.1.29,3.A.1.1.9 Bacteria 1TQFY@1239,3F5UU@33958,4HBB0@91061,COG4209@1,COG4209@2 NA|NA|NA U Binding-protein-dependent transport system inner membrane component PGHMIELC_02635 220668.lp_3645 0.0 1229.5 Lactobacillaceae 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 GH20 Bacteria 1TRN0@1239,3F42P@33958,4HCG4@91061,COG3525@1,COG3525@2 NA|NA|NA G Glycosyl hydrolase family 20, catalytic domain PGHMIELC_02636 220668.lp_3646 6.5e-156 556.6 Lactobacillaceae Bacteria 1UV2E@1239,3F665@33958,4I2JX@91061,COG2207@1,COG2207@2 NA|NA|NA K AraC-like ligand binding domain PGHMIELC_02637 220668.lp_3647 0.0 1129.4 Lactobacillaceae mdlA2 ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter PGHMIELC_02638 220668.lp_3648 0.0 1075.8 Lactobacillaceae yknV ko:K02021,ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter PGHMIELC_02639 220668.lp_3649 8.4e-193 679.5 Lactobacillaceae rliB ko:K02103 ko00000,ko03000 Bacteria 1UV2F@1239,3F58N@33958,4I2WX@91061,COG1609@1,COG1609@2 NA|NA|NA K helix_turn_helix gluconate operon transcriptional repressor PGHMIELC_02640 220668.lp_3650 6.8e-156 556.6 Lactobacillaceae lrp ko:K02647,ko:K09684,ko:K17319 ko02010,map02010 M00603 ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.1.29,3.A.1.1.9 Bacteria 1V649@1239,3F7G1@33958,4HHCD@91061,COG2508@1,COG2508@2 NA|NA|NA QT PucR C-terminal helix-turn-helix domain PGHMIELC_02641 220668.lp_3652 8.6e-63 246.1 Lactobacillaceae srlB GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0051179,GO:0051234,GO:0071702 2.7.1.198 ko:K02781 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 iB21_1397.B21_02519,iEC55989_1330.EC55989_2966,iECBD_1354.ECBD_1021,iECB_1328.ECB_02554,iECD_1391.ECD_02554,iECIAI39_1322.ECIAI39_2890,iECO111_1330.ECO111_3422,iECO26_1355.ECO26_3767,iECSE_1348.ECSE_2952,iECSP_1301.ECSP_3652,iECW_1372.ECW_m2903,iECs_1301.ECs3560,iEKO11_1354.EKO11_1071,iEcE24377_1341.EcE24377A_2988,iEcHS_1320.EcHS_A2840,iEcolC_1368.EcolC_1008,iG2583_1286.G2583_3352,iSSON_1240.SSON_2848,iWFL_1372.ECW_m2903,iZ_1308.Z4011 Bacteria 1VG8V@1239,3F7KY@33958,4HPTF@91061,COG3731@1,COG3731@2 NA|NA|NA G PTS system glucitol/sorbitol-specific IIA component PGHMIELC_02642 220668.lp_3653 1e-174 619.4 Lactobacillaceae srlE GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0090563 2.7.1.198 ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 Bacteria 1TQ8F@1239,3F5AP@33958,4HA7E@91061,COG3732@1,COG3732@2 NA|NA|NA G Sorbitol phosphotransferase enzyme II N-terminus PGHMIELC_02643 220668.lp_3654 2e-100 371.7 Lactobacillaceae srlA GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 ko:K02783 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.4.1 iSBO_1134.SBO_2816 Bacteria 1URER@1239,3F445@33958,4HEHX@91061,COG3730@1,COG3730@2 NA|NA|NA G PTS system enzyme II sorbitol-specific factor PGHMIELC_02644 220668.lp_3655 1.1e-86 325.9 Lactobacillaceae gutM GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02466 ko00000 Bacteria 1VHYU@1239,3F7F5@33958,4HP9S@91061,COG4578@1,COG4578@2 NA|NA|NA K Glucitol operon activator protein (GutM) PGHMIELC_02645 220668.lp_3656 0.0 1191.0 Lactobacillaceae srlM 2.7.1.194,2.7.1.200,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02821,ko:K03491,ko:K11201 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00306,M00550 R03232,R05570,R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5.1,4.A.7.1 Bacteria 1UZ36@1239,3F5E0@33958,4HDUK@91061,COG1762@1,COG1762@2,COG3711@1,COG3711@2 NA|NA|NA GKT Mga helix-turn-helix domain PGHMIELC_02646 220668.lp_3657 1.5e-144 518.8 Lactobacillaceae Bacteria 1TP2V@1239,3F4CR@33958,4HCAG@91061,COG1028@1,COG1028@2 NA|NA|NA IQ NAD dependent epimerase/dehydratase family PGHMIELC_02647 220668.lp_3658 2.7e-160 571.2 Lactobacillaceae rbsU ko:K05340,ko:K06216 ko00000,ko02000 2.A.7.5 Bacteria 1UBJV@1239,3FB9E@33958,4HB7E@91061,COG4975@1,COG4975@2 NA|NA|NA U ribose uptake protein RbsU PGHMIELC_02648 220668.lp_3659 7.9e-67 259.6 Lactobacillaceae rbsD GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009056,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016052,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0016887,GO:0017111,GO:0019303,GO:0019321,GO:0019323,GO:0022804,GO:0022857,GO:0034219,GO:0042623,GO:0042626,GO:0042802,GO:0043211,GO:0043492,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:1901575 5.4.99.62 ko:K06726 ko02010,map02010 R08247 RC02247 ko00000,ko00001,ko01000 iAF1260.b3748,iBWG_1329.BWG_3439,iECDH10B_1368.ECDH10B_3936,iECDH1ME8569_1439.ECDH1ME8569_3636,iECH74115_1262.ECH74115_5184,iECSP_1301.ECSP_4798,iECs_1301.ECs4690,iETEC_1333.ETEC_4039,iEcDH1_1363.EcDH1_4219,iJO1366.b3748,iJR904.b3748,iY75_1357.Y75_RS18330 Bacteria 1VA2V@1239,3F6GA@33958,4HIFW@91061,COG1869@1,COG1869@2 NA|NA|NA G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose PGHMIELC_02649 220668.lp_3660 2.3e-162 578.2 Lactobacillaceae rbsK 2.7.1.15 ko:K00852 ko00030,map00030 R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TQRC@1239,3F3S5@33958,4HA87@91061,COG0524@1,COG0524@2 NA|NA|NA H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway PGHMIELC_02650 220668.lp_3661 5.9e-188 663.3 Lactobacillaceae rbsR ko:K02529 ko00000,ko03000 Bacteria 1TQ7K@1239,3FC5C@33958,4H9V1@91061,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor PGHMIELC_02651 220668.lp_3662 0.0 1716.8 Lactobacillaceae adhE 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 Bacteria 1TPB4@1239,3F3RN@33958,4HAN8@91061,COG1012@1,COG1012@2,COG1454@1,COG1454@2 NA|NA|NA C belongs to the iron- containing alcohol dehydrogenase family PGHMIELC_02652 220668.lp_3663 2.7e-79 301.2 Lactobacillaceae Bacteria 1W0BR@1239,3F5SB@33958,4HXYP@91061,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein family PGHMIELC_02653 220668.lp_3664 2.2e-99 368.2 Lactobacillaceae padR Bacteria 1V6TJ@1239,3F70A@33958,4HKXY@91061,COG1695@1,COG1695@2 NA|NA|NA K Virulence activator alpha C-term PGHMIELC_02654 220668.lp_3665 1.7e-104 385.2 Lactobacillaceae padC ko:K13727 ko00000,ko01000 Bacteria 1UY0X@1239,3F4P4@33958,4HAN3@91061,COG3479@1,COG3479@2 NA|NA|NA Q Phenolic acid decarboxylase PGHMIELC_02655 220668.lp_3666 5.5e-144 516.9 Lactobacillaceae tesE ko:K02509 ko00350,ko01120,map00350,map01120 R04132,R06897 RC01615,RC02595 ko00000,ko00001,ko01000 Bacteria 1TQVG@1239,3F515@33958,4HBMC@91061,COG3971@1,COG3971@2 NA|NA|NA Q hydratase PGHMIELC_02656 220668.lp_3668 2.2e-87 328.2 Lactobacillaceae yjaB_1 ko:K03826 ko00000,ko01000 Bacteria 1VAYE@1239,3F4YE@33958,4HM99@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain PGHMIELC_02657 220668.lp_3669 1e-156 559.3 Lactobacillaceae degV Bacteria 1V289@1239,3F4D9@33958,4I3AR@91061,COG1307@1,COG1307@2 NA|NA|NA S DegV family PGHMIELC_02658 220668.lp_3672 2.4e-58 231.5 Lactobacillaceae 2.6.1.2,2.6.1.66 ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 Bacteria 1UUXA@1239,3F6H3@33958,4IFHI@91061,COG1396@1,COG1396@2 NA|NA|NA K Bacteriophage CI repressor helix-turn-helix domain PGHMIELC_02659 220668.lp_3673 2.8e-254 884.0 Lactobacillaceae pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 1TRJN@1239,3F3QA@33958,4HBZ9@91061,COG3579@1,COG3579@2 NA|NA|NA E aminopeptidase PGHMIELC_02661 220668.lp_3675 1.2e-108 399.1 Lactobacillaceae lepB 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1V5YR@1239,3FBKW@33958,4IR1X@91061,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family PGHMIELC_02662 220668.lp_3676 3.8e-303 1046.6 Lactobacillaceae Bacteria 1U7DB@1239,29Q2R@1,30B1D@2,3F9EZ@33958,4IH97@91061 NA|NA|NA PGHMIELC_02664 220668.lp_3678 1.2e-159 569.3 Lactobacillaceae Bacteria 1V92G@1239,3F97P@33958,4HIJ2@91061,COG4072@1,COG4072@2 NA|NA|NA S Bacterial protein of unknown function (DUF916) PGHMIELC_02665 220668.lp_3679 6.9e-93 347.1 Lactobacillaceae Bacteria 1U5KE@1239,2BM49@1,32FMM@2,3F64S@33958,4IFB7@91061 NA|NA|NA S Cell surface protein PGHMIELC_02666 220668.lp_3681 0.0 1264.6 Lactobacillaceae gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 ko:K03495 R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 Bacteria 1TQ4B@1239,3F454@33958,4HA6S@91061,COG0445@1,COG0445@2 NA|NA|NA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 PGHMIELC_02667 220668.lp_3682 4.6e-255 886.7 Lactobacillaceae mnmE GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K03650 R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 Bacteria 1TPJF@1239,3F3WA@33958,4HA06@91061,COG0486@1,COG0486@2 NA|NA|NA S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 PGHMIELC_02668 220668.lp_3683 2.5e-130 471.9 Lactobacillaceae jag ko:K06346 ko00000 Bacteria 1V3IN@1239,3F5WG@33958,4HHHU@91061,COG1847@1,COG1847@2 NA|NA|NA S R3H domain protein PGHMIELC_02669 220668.lp_3684 9.3e-239 832.4 Lactobacillaceae Bacteria 1TQQ0@1239,3F4D3@33958,4HDKW@91061,COG1228@1,COG1228@2 NA|NA|NA Q Imidazolonepropionase and related amidohydrolases PGHMIELC_02670 220668.lp_3686 5e-309 1066.2 Lactobacillaceae ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F3JE@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substratebinding protein PGHMIELC_02671 220668.lp_3687 1.8e-105 389.0 Lactobacillaceae yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 1TQ0J@1239,3F3SD@33958,4HB3J@91061,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins PGHMIELC_02672 1136177.KCA1_3018 6.4e-57 226.5 Lactobacillaceae rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536,ko:K08998 ko00000,ko01000,ko03016 Bacteria 1VA78@1239,3F6GS@33958,4HKG6@91061,COG0594@1,COG0594@2 NA|NA|NA J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme PGHMIELC_02673 220668.lp_0001 9.1e-256 889.0 Lactobacillaceae dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 1TPV7@1239,3F3YA@33958,4H9MW@91061,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids PGHMIELC_02674 220668.lp_0002 2e-208 731.5 Lactobacillaceae dnaN 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TQ7J@1239,3F3ZQ@33958,4H9TF@91061,COG0592@1,COG0592@2 NA|NA|NA L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria PGHMIELC_02675 220668.lp_0004 5e-37 159.8 Lactobacillaceae yaaA GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K14761 ko00000,ko03009 Bacteria 1VEJ2@1239,3F803@33958,4HNMC@91061,COG2501@1,COG2501@2 NA|NA|NA S S4 domain protein YaaA PGHMIELC_02676 220668.lp_0005 1.9e-206 724.9 Lactobacillaceae recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1TP9U@1239,3F3Q1@33958,4HA0W@91061,COG1195@1,COG1195@2 NA|NA|NA L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP PGHMIELC_02677 220668.lp_0006 0.0 1283.1 Lactobacillaceae gyrB GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02470,ko:K02622 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TQ0R@1239,3F48M@33958,4H9Y6@91061,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner PGHMIELC_02678 220668.lp_0007 0.0 1475.3 Lactobacillaceae gyrA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TP2Z@1239,3F3YM@33958,4HAHY@91061,COG0188@1,COG0188@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner PGHMIELC_02679 1136177.KCA1_0007 1.5e-49 201.8 Lactobacillaceae rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 ko:K02990 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VA18@1239,3F6ZY@33958,4HKHD@91061,COG0360@1,COG0360@2 NA|NA|NA J Binds together with S18 to 16S ribosomal RNA PGHMIELC_02680 220668.lp_0010 6.8e-62 243.8 Lactobacillaceae ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 1V3WT@1239,3F66N@33958,4HH8I@91061,COG0629@1,COG0629@2 NA|NA|NA L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism PGHMIELC_02681 220668.lp_0011 6.2e-35 152.9 Lactobacillaceae rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963,ko:K03111,ko:K15125 ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133 M00178 br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400 Bacteria 1V9XS@1239,3F7CY@33958,4HKCC@91061,COG0238@1,COG0238@2 NA|NA|NA J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit PGHMIELC_02682 220668.lp_0012 0.0 1288.9 Lactobacillaceae yybT Bacteria 1TPGP@1239,3F3TY@33958,4HBVH@91061,COG3887@1,COG3887@2 NA|NA|NA T signaling protein consisting of a modified GGDEF domain and a DHH domain PGHMIELC_02683 220668.lp_0013 1.4e-67 262.3 Lactobacillaceae rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6QG@1239,3F68P@33958,4HIKJ@91061,COG0359@1,COG0359@2 NA|NA|NA J Binds to the 23S rRNA PGHMIELC_02684 220668.lp_0014 7.8e-242 842.8 Lactobacillaceae dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 1TPCT@1239,3F4MW@33958,4H9Y8@91061,COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication PGHMIELC_02685 220668.lp_0015 2e-225 788.1 Lactobacillaceae yttB Bacteria 1TPJ6@1239,3F4F9@33958,4HAGJ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_02686 220668.lp_0016 3.6e-143 514.2 Lactobacillaceae proB GO:0003674,GO:0003824,GO:0004349,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016772,GO:0016774,GO:0016903,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPG6@1239,3F4E1@33958,4HA9B@91061,COG0263@1,COG0263@2 NA|NA|NA F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate PGHMIELC_02687 220668.lp_0017 5e-229 800.0 Lactobacillaceae proA GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iLJ478.TM0293,iYL1228.KPN_00280,iYO844.BSU13130 Bacteria 1TQ9V@1239,3F3W7@33958,4HB7B@91061,COG0014@1,COG0014@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate PGHMIELC_02689 220668.lp_0018 1.2e-275 955.3 Lactobacillaceae ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F3JE@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substratebinding protein PGHMIELC_02691 220668.lp_0020 0.0 1339.7 Lactobacillaceae glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,3.2.1.141,3.2.1.20 ko:K00700,ko:K01187,ko:K01236,ko:K17734 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 M00565 R00028,R00801,R00802,R02110,R06087,R06088,R09995,R11256 RC00028,RC00049,RC00077 ko00000,ko00001,ko00002,ko01000,ko01002,ko04147 CBM48,GH13,GH31 iAPECO1_1312.APECO1_3025,iECNA114_1301.ECNA114_3542,iECOK1_1307.ECOK1_3857,iECS88_1305.ECS88_3830,iECSF_1327.ECSF_3253,iJN678.glgB,iLF82_1304.LF82_0837,iNRG857_1313.NRG857_17030,iUTI89_1310.UTI89_C3941 Bacteria 1TP4M@1239,3F4KT@33958,4HAPM@91061,COG0296@1,COG0296@2 NA|NA|NA G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position PGHMIELC_02692 220668.lp_0021 1.5e-214 751.9 Lactobacillaceae glgC 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TNZW@1239,3F4IA@33958,4HAZX@91061,COG0448@1,COG0448@2 NA|NA|NA H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans PGHMIELC_02693 220668.lp_0022 6.3e-197 693.3 Lactobacillaceae glgD 2.4.1.21,2.7.7.27 ko:K00703,ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948,R02421 RC00002,RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 GT5 Bacteria 1TPZ3@1239,3F58E@33958,4H9UQ@91061,COG0448@1,COG0448@2 NA|NA|NA G Nucleotidyl transferase PGHMIELC_02694 220668.lp_0023 3.1e-278 963.8 Lactobacillaceae glgA GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 GT5 Bacteria 1TQ4M@1239,3F3PP@33958,4HAVA@91061,COG0297@1,COG0297@2 NA|NA|NA F Synthesizes alpha-1,4-glucan chains using ADP-glucose PGHMIELC_02695 220668.lp_0024 0.0 1609.3 Lactobacillaceae glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 R02111 ko00000,ko00001,ko01000 GT35 iYO844.BSU30940 Bacteria 1TQAJ@1239,3F4Z1@33958,4H9XI@91061,COG0058@1,COG0058@2 NA|NA|NA G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties PGHMIELC_02696 220668.lp_0025 3.8e-303 1046.6 Lactobacillaceae malQ 2.4.1.25,3.2.1.20,3.2.1.41 ko:K00705,ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 R00028,R00801,R00802,R02111,R05196,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 CBM48,GH13,GH31,GH77 Bacteria 1TNZ0@1239,3F41N@33958,4HB67@91061,COG0366@1,COG0366@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family PGHMIELC_02698 220668.lp_0026 4.5e-143 513.8 Lactobacillaceae Bacteria 1TSZZ@1239,3F49K@33958,4HB54@91061,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase PGHMIELC_02699 220668.lp_0027 1e-119 436.0 Lactobacillaceae pgmB GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008801,GO:0009058,GO:0009292,GO:0009294,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016853,GO:0016866,GO:0016868,GO:0019203,GO:0030312,GO:0033554,GO:0034637,GO:0040007,GO:0042221,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046351,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0071704,GO:0071944,GO:1901576 2.4.1.64,3.1.3.12,3.2.1.28,5.4.2.6 ko:K01087,ko:K01194,ko:K01838,ko:K05342 ko00500,ko01100,map00500,map01100 R00010,R02727,R02728,R02778,R11310 RC00017,RC00049,RC00408 ko00000,ko00001,ko00537,ko01000 GH37,GH65 Bacteria 1UY8N@1239,3F4ST@33958,4HF3K@91061,COG0637@1,COG0637@2 NA|NA|NA S beta-phosphoglucomutase PGHMIELC_02700 220668.lp_0028 0.0 1820.8 Lactobacillaceae trePP GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0030312,GO:0044464,GO:0071944 2.4.1.216,2.4.1.8,3.1.3.12,3.2.1.28 ko:K00691,ko:K01087,ko:K01194,ko:K03731 ko00500,ko01100,map00500,map01100 R00010,R01555,R02778 RC00017,RC00049 ko00000,ko00001,ko00537,ko01000 GH37,GH65 Bacteria 1TQMB@1239,3F4TB@33958,4HD7Z@91061,COG1554@1,COG1554@2 NA|NA|NA G Glycosyl hydrolase family 65 central catalytic domain PGHMIELC_02701 220668.lp_0030 1.3e-78 298.9 Lactobacillaceae Bacteria 1V1KZ@1239,3F7W7@33958,4I1P9@91061,COG3871@1,COG3871@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase PGHMIELC_02702 220668.lp_0031 1.6e-31 141.4 Lactobacillaceae cspA ko:K03704 ko00000,ko03000 Bacteria 1VEE0@1239,3F7R5@33958,4IG6G@91061,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein domain PGHMIELC_02703 220668.lp_0032 1.7e-37 161.4 Lactobacillaceae Bacteria 1W1QU@1239,2CH90@1,2ZP4M@2,3F7JH@33958,4I01G@91061 NA|NA|NA PGHMIELC_02705 1136177.KCA1_0029 6.2e-131 473.4 Lactobacillaceae Bacteria 1TPQG@1239,3F4FB@33958,4HA8Q@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator PGHMIELC_02706 220668.lp_0037 0.0 1185.2 Lactobacillaceae vicK 2.7.13.3 ko:K07652 ko02020,map02020 M00459 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQ1H@1239,3F45G@33958,4HA52@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase PGHMIELC_02707 220668.lp_0038 2e-244 851.3 Lactobacillaceae yycH Bacteria 1V32Y@1239,3F4HR@33958,4HG2Q@91061,COG4863@1,COG4863@2 NA|NA|NA S YycH protein PGHMIELC_02708 220668.lp_0039 2.9e-151 541.2 Lactobacillaceae yycI Bacteria 1V1FW@1239,3F3PV@33958,4HFWZ@91061,COG4853@1,COG4853@2 NA|NA|NA S YycH protein PGHMIELC_02709 220668.lp_0041 8.9e-158 562.8 Lactobacillaceae vicX 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 1TQ8E@1239,3F3S4@33958,4HAKD@91061,COG1235@1,COG1235@2 NA|NA|NA S domain protein PGHMIELC_02710 220668.lp_0043 6.8e-173 613.6 Lactobacillaceae htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04691,ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1TRM8@1239,3F45X@33958,4HA31@91061,COG0265@1,COG0265@2 NA|NA|NA O serine protease PGHMIELC_02711 220668.lp_0045 1.2e-82 312.4 Lactobacillaceae rlmH 2.1.1.177 ko:K00783 ko00000,ko01000,ko03009 Bacteria 1V3JM@1239,3F3YX@33958,4HFP8@91061,COG1576@1,COG1576@2 NA|NA|NA J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA PGHMIELC_02712 220668.lp_0046 7.6e-95 353.2 Lactobacillaceae Bacteria 1UUX8@1239,3F81V@33958,4IGCB@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family PGHMIELC_02713 220668.lp_0047 1.5e-31 141.7 Lactobacillaceae calB 1.2.1.68 ko:K00154 ko00000,ko01000 Bacteria 1TP4S@1239,3F47F@33958,4H9MF@91061,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family PGHMIELC_02714 797515.HMPREF9103_01821 3.2e-30 137.1 Lactobacillaceae Bacteria 1U69B@1239,29P8A@1,30A6D@2,3F7CJ@33958,4IG0G@91061 NA|NA|NA PGHMIELC_02715 1045004.OKIT_0906 4.1e-76 291.6 Bacilli Bacteria 1VPIB@1239,2EN0Y@1,33FP4@2,4HRWI@91061 NA|NA|NA PGHMIELC_02717 908339.HMPREF9265_1755 1e-223 782.7 Lactobacillaceae traK ko:K03205 ko03070,map03070 M00333 ko00000,ko00001,ko00002,ko02044 3.A.7 Bacteria 1TPCF@1239,3F4S3@33958,4H9ZN@91061,COG3505@1,COG3505@2 NA|NA|NA U TraM recognition site of TraD and TraG PGHMIELC_02718 797515.HMPREF9103_01698 2e-66 258.5 Lactobacillaceae Bacteria 1U59I@1239,2AC4N@1,311NX@2,3F59S@33958,4IF0X@91061 NA|NA|NA PGHMIELC_02719 797515.HMPREF9103_01697 5.7e-43 180.3 Lactobacillaceae Bacteria 1U5XH@1239,3F6NC@33958,4IFKV@91061,COG0526@1,COG0526@2 NA|NA|NA CO COG0526, thiol-disulfide isomerase and thioredoxins PGHMIELC_02720 908339.HMPREF9265_1758 1.8e-54 219.2 Lactobacillaceae Bacteria 1UFKJ@1239,29UXR@1,30GAH@2,3F46S@33958,4IEU2@91061 NA|NA|NA PGHMIELC_02721 1045004.OKIT_0901 6.6e-162 577.0 Bacilli ko:K03199 ko03070,map03070 M00333 ko00000,ko00001,ko00002,ko02044 3.A.7 Bacteria 1VW67@1239,4HWSY@91061,COG0741@1,COG0741@2,COG0791@1,COG0791@2 NA|NA|NA M CHAP domain PGHMIELC_02722 1291743.LOSG293_220170 1.6e-231 808.5 Lactobacillaceae polC 2.4.1.129,2.7.7.7,3.4.16.4 ko:K03763,ko:K05366 ko00230,ko00240,ko00550,ko01100,ko01501,ko03030,ko03430,ko03440,map00230,map00240,map00550,map01100,map01501,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko01003,ko01011,ko03032,ko03400 GT51 Bacteria 1V1PS@1239,3F450@33958,4HGKF@91061,COG4499@1,COG4499@2 NA|NA|NA S WXG100 protein secretion system (Wss), protein YukC PGHMIELC_02723 1045004.OKIT_0528 0.0 1305.0 Bacilli traE Bacteria 1TPDR@1239,4IQVJ@91061,COG3451@1,COG3451@2 NA|NA|NA U Psort location Cytoplasmic, score PGHMIELC_02724 1291743.LOSG293_220150 1.4e-116 425.6 Lactobacillaceae Bacteria 1VEP6@1239,2ECAZ@1,3369B@2,3F5SZ@33958,4HQSU@91061 NA|NA|NA PGHMIELC_02725 908339.HMPREF9265_1763 7.8e-37 159.8 Lactobacillaceae Bacteria 1VVYR@1239,2F48Y@1,33WZQ@2,3F6NH@33958,4HW55@91061 NA|NA|NA PGHMIELC_02726 1045004.OKIT_0525 5.7e-50 203.4 Bacilli Bacteria 1VHPT@1239,2BZG5@1,3316I@2,4HPFA@91061 NA|NA|NA S Cag pathogenicity island, type IV secretory system PGHMIELC_02727 1045004.OKIT_0524 3e-81 308.1 Bacilli Bacteria 1W4Z7@1239,2DDVG@1,2ZJFE@2,4I0TA@91061 NA|NA|NA PGHMIELC_02728 1138822.PL11_10155 2.6e-14 84.7 Lactobacillaceae Bacteria 1U6EB@1239,29PC9@1,30AAH@2,3F7QB@33958,4IG63@91061 NA|NA|NA PGHMIELC_02729 1423815.BACR01000048_gene2301 0.0 1115.1 Lactobacillaceae Bacteria 1VQWC@1239,3F4DP@33958,4HD6B@91061,COG0507@1,COG0507@2 NA|NA|NA L MobA MobL family protein PGHMIELC_02730 1423734.JCM14202_2802 9.4e-27 125.6 Lactobacillaceae Bacteria 1U69C@1239,29P8B@1,30A6E@2,3F7CM@33958,4IG0H@91061 NA|NA|NA PGHMIELC_02731 1400520.LFAB_17320 2.6e-40 171.0 Lactobacillaceae Bacteria 1VKZC@1239,2EJES@1,33D5R@2,3F6Y2@33958,4HRGI@91061 NA|NA|NA PGHMIELC_02732 1423780.LOT_2224 5.4e-84 317.0 Lactobacillaceae Bacteria 1VQDB@1239,2EHZR@1,33BR8@2,3F5IT@33958,4HRJT@91061 NA|NA|NA PGHMIELC_02733 1423734.JCM14202_2806 9.6e-43 179.1 Lactobacillaceae relB ko:K07473 ko00000,ko02048 Bacteria 1VGJW@1239,3F72D@33958,4HR7A@91061,COG3077@1,COG3077@2 NA|NA|NA L Addiction module antitoxin, RelB DinJ family PGHMIELC_02734 1423734.JCM14202_2807 1.2e-82 312.4 Lactobacillaceae repA Bacteria 1VHQA@1239,2DP1C@1,3304N@2,3F55E@33958,4HPY6@91061 NA|NA|NA S Replication initiator protein A PGHMIELC_02735 1423780.LOT_2226 9e-49 199.5 Lactobacillaceae repA Bacteria 1VHQA@1239,2DP1C@1,3304N@2,3F55E@33958,4HPY6@91061 NA|NA|NA S Replication initiator protein A PGHMIELC_02736 1400520.LFAB_17340 4.3e-245 853.6 Lactobacillaceae cycA GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease PGHMIELC_02738 1400520.LFAB_17345 8.3e-37 159.1 Lactobacillaceae ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972,ko:K10754 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 M00289,M00295 R00382 RC00005 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1U6VR@1239,3F8K9@33958,4IGPT@91061,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA PGHMIELC_02739 1400520.LFAB_17350 2.7e-143 514.6 Lactobacillaceae Bacteria 1TP8S@1239,3F4QA@33958,4HCBZ@91061,COG1192@1,COG1192@2 NA|NA|NA D CobQ CobB MinD ParA nucleotide binding domain protein PGHMIELC_02741 511437.Lbuc_0041 2.1e-36 157.9 Lactobacillaceae Bacteria 1TRSF@1239,3F3WY@33958,4HTRR@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family PGHMIELC_02743 1045004.OKIT_0514 2.4e-124 451.4 Leuconostocaceae tnp ko:K07498 ko00000 Bacteria 1TTKR@1239,4AXG2@81850,4HCB4@91061,COG3316@1,COG3316@2 NA|NA|NA L DDE domain PGHMIELC_02744 913848.AELK01000010_gene1160 8.3e-94 349.7 Lactobacillaceae pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 Bacteria 1TPDW@1239,3F3K7@33958,4HAI4@91061,COG1488@1,COG1488@2 NA|NA|NA F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP PGHMIELC_02745 525309.HMPREF0494_0082 5.2e-168 597.0 Lactobacillaceae traI 5.99.1.2 ko:K03169 ko00000,ko01000,ko03032 Bacteria 1TPJD@1239,3F4W6@33958,4HAZV@91061,COG0550@1,COG0550@2 NA|NA|NA L This gene contains a nucleotide ambiguity which may be the result of a sequencing error PGHMIELC_02746 1423780.LOT_2221 0.0 1287.7 Lactobacillaceae Bacteria 1VQWC@1239,3F4DP@33958,4HD6B@91061,COG0507@1,COG0507@2 NA|NA|NA L MobA MobL family protein PGHMIELC_02747 1423734.JCM14202_2802 5.5e-27 126.3 Lactobacillaceae Bacteria 1U69C@1239,29P8B@1,30A6E@2,3F7CM@33958,4IG0H@91061 NA|NA|NA PGHMIELC_02748 1423807.BACO01000083_gene2425 1.5e-40 171.8 Lactobacillaceae Bacteria 1VKZC@1239,2EJES@1,33D5R@2,3F6Y2@33958,4HRGI@91061 NA|NA|NA PGHMIELC_02749 1423780.LOT_2224 2.3e-82 311.6 Lactobacillaceae Bacteria 1VQDB@1239,2EHZR@1,33BR8@2,3F5IT@33958,4HRJT@91061 NA|NA|NA PGHMIELC_02750 1045004.OKIT_0519 1.1e-43 182.2 Bacilli relB ko:K07473 ko00000,ko02048 Bacteria 1VGJW@1239,4HR7A@91061,COG3077@1,COG3077@2 NA|NA|NA L Addiction module antitoxin, RelB DinJ family PGHMIELC_02752 1231377.C426_1826 3.8e-98 364.8 Bacilli soj ko:K03496 ko00000,ko03036,ko04812 Bacteria 1TP8S@1239,4HCBZ@91061,COG1192@1,COG1192@2 NA|NA|NA D CobQ CobB MinD ParA nucleotide binding domain protein PGHMIELC_02753 46256.BBIK01000029_gene1876 4.6e-11 73.9 Leuconostocaceae Bacteria 1U3QE@1239,2ESYV@1,308NB@2,4AYTS@81850,4IDHB@91061 NA|NA|NA PGHMIELC_02754 511437.Lbuc_2227 6.3e-176 623.2 Lactobacillaceae Bacteria 1TRSF@1239,3F3WY@33958,4HTRR@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family PGHMIELC_02755 1114972.AUAW01000027_gene720 9.8e-188 662.5 Lactobacillaceae Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region PGHMIELC_02756 1423806.JCM15457_1481 1.6e-99 369.4 Lactobacillaceae gbuC ko:K02001,ko:K02002 ko02010,map02010 M00208 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1TP82@1239,3F4B3@33958,4H9MM@91061,COG2113@1,COG2113@2 NA|NA|NA E glycine betaine PGHMIELC_02757 1291743.LOSG293_190030 5.3e-113 414.1 Lactobacillaceae proW ko:K02001,ko:K02002 ko02010,map02010 M00208 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1UHRI@1239,3F4W7@33958,4IS7D@91061,COG4176@1,COG4176@2 NA|NA|NA E glycine betaine PGHMIELC_02758 1302286.BAOT01000072_gene2188 9.6e-185 652.9 Lactobacillaceae gbuA 3.6.1.1,3.6.3.32 ko:K02000,ko:K15986 ko00190,ko02010,map00190,map02010 M00208 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 Bacteria 1UHNE@1239,3FC38@33958,4HA9P@91061,COG2524@1,COG2524@2,COG4175@1,COG4175@2 NA|NA|NA E glycine betaine PGHMIELC_02759 334390.LAF_0161 7.7e-188 662.9 Lactobacillaceae ko:K07482 ko00000 Bacteria 1TRSF@1239,3FB5X@33958,4HCMP@91061,COG2826@1,COG2826@2 NA|NA|NA L Helix-turn-helix domain PGHMIELC_02760 1123359.AUIQ01000090_gene154 2.5e-95 354.8 Enterococcaceae tnpR1 Bacteria 1V51N@1239,4B0ZS@81852,4HDX2@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain PGHMIELC_02761 1400520.LFAB_17405 4.8e-57 227.3 Lactobacillaceae Bacteria 1U65M@1239,3F74C@33958,4IFVG@91061,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein PGHMIELC_02762 797515.HMPREF9103_01322 0.0 1102.4 Lactobacillaceae kup GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 ko:K03549 ko00000,ko02000 2.A.72 Bacteria 1TRUQ@1239,3F4CU@33958,4HA8Z@91061,COG3158@1,COG3158@2 NA|NA|NA P Transport of potassium into the cell PGHMIELC_02763 158787.BSCA_1981 5e-64 251.1 Bifidobacteriales Bacteria 2GJ2N@201174,4CZDR@85004,COG0745@1,COG0745@2 NA|NA|NA KT Transcriptional regulatory protein, C terminal PGHMIELC_02764 632245.CLP_3545 3.8e-181 642.1 Clostridiaceae Bacteria 1TQHB@1239,247S4@186801,36DXC@31979,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor PGHMIELC_02765 1280689.AUJC01000009_gene3386 5.2e-38 164.5 Clostridiaceae kdpC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 ko:K01548 ko02020,map02020 ko00000,ko00001,ko01000 3.A.3.7 iEcE24377_1341.EcE24377A_0722,ic_1306.c0781 Bacteria 1V4GE@1239,24G0R@186801,36FMY@31979,COG2156@1,COG2156@2 NA|NA|NA P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex PGHMIELC_02766 1232453.BAIF02000098_gene3901 1.3e-253 882.5 Clostridia kdpB 3.6.3.12 ko:K01547 ko02020,map02020 ko00000,ko00001,ko01000 3.A.3.7 iAF987.Gmet_2434 Bacteria 1TPV5@1239,24835@186801,COG2216@1,COG2216@2 NA|NA|NA P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system PGHMIELC_02767 469596.HMPREF9488_02060 2.1e-175 622.5 Erysipelotrichia kdpA GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 ko:K01546 ko02020,map02020 ko00000,ko00001,ko01000 3.A.3.7 iAPECO1_1312.APECO1_1369,iECUMN_1333.ECUMN_0780,iYL1228.KPN_00717 Bacteria 1TPDF@1239,3VP8A@526524,COG2060@1,COG2060@2 NA|NA|NA P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane PGHMIELC_02769 1410658.JHWI01000022_gene1118 1.3e-28 133.7 Firmicutes 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 1VXCA@1239,COG2114@1,COG2114@2 NA|NA|NA T Pfam Adenylate and Guanylate cyclase catalytic domain PGHMIELC_02771 1133569.AHYZ01000003_gene559 1.1e-250 872.1 Lactobacillaceae uvrX 2.7.7.7 ko:K02346,ko:K03502,ko:K14161 ko00000,ko01000,ko03400 Bacteria 1TP42@1239,3F3WN@33958,4HA1P@91061,COG0389@1,COG0389@2 NA|NA|NA L Belongs to the DNA polymerase type-Y family PGHMIELC_02772 1138822.PL11_10545 2.3e-53 214.5 Lactobacillaceae Bacteria 1W2PF@1239,28WF1@1,2ZIF8@2,3F8BE@33958,4HZUK@91061 NA|NA|NA PGHMIELC_02773 1133569.AHYZ01000003_gene561 5.1e-66 256.9 Lactobacillaceae Bacteria 1VKJ5@1239,2EIVY@1,33CM8@2,3F7QM@33958,4HRQ2@91061 NA|NA|NA PGHMIELC_02774 398511.BpOF4_03745 1.3e-10 74.3 Bacillus Bacteria 1VVFC@1239,1ZJ5N@1386,29RYS@1,30D33@2,4IM4S@91061 NA|NA|NA S Protein of unknown function (DUF3800) PGHMIELC_02775 1133569.AHYZ01000017_gene1019 1.1e-125 456.1 Lactobacillaceae Bacteria 1TQN4@1239,3F5I0@33958,4HKTX@91061,COG4227@1,COG4227@2 NA|NA|NA L Psort location Cytoplasmic, score PGHMIELC_02776 220668.lp_0305 9.7e-67 259.2 Lactobacillaceae gcvH GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006520,GO:0006544,GO:0006546,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016054,GO:0017144,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019464,GO:0019538,GO:0019752,GO:0031405,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0036211,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051604,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901681 ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 iE2348C_1286.E2348C_3156,iNJ661.Rv1826,iPC815.YPO0906 Bacteria 1U670@1239,3F784@33958,4IFXJ@91061,COG0509@1,COG0509@2 NA|NA|NA E Glycine cleavage H-protein PGHMIELC_02777 220668.lp_0306 7.4e-177 626.3 Lactobacillaceae sepS16B Bacteria 1US2T@1239,28MN3@1,2ZAXQ@2,3F55K@33958,4HW4H@91061 NA|NA|NA PGHMIELC_02778 220668.lp_0307 1.3e-131 475.7 Lactobacillaceae Bacteria 1VJZJ@1239,2EEPZ@1,338HP@2,3F55G@33958,4HR6K@91061 NA|NA|NA PGHMIELC_02779 220668.lp_0308 0.0 1568.5 Lactobacillaceae dinG 3.1.12.1,3.6.4.12 ko:K07464,ko:K10844 ko03022,ko03420,map03022,map03420 M00290 ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400 Bacteria 1TPNB@1239,3F473@33958,4HD6T@91061,COG1199@1,COG1199@2 NA|NA|NA KL DEAD_2 PGHMIELC_02780 220668.lp_0309 6.8e-57 226.5 Lactobacillaceae Bacteria 1U63U@1239,29P4E@1,30A2M@2,3F6Z3@33958,4IFTA@91061 NA|NA|NA PGHMIELC_02781 220668.lp_0310 8.9e-223 779.2 Lactobacillaceae ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0409 Bacteria 1TQ22@1239,3F48Z@33958,4HA7K@91061,COG0282@1,COG0282@2 NA|NA|NA F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction PGHMIELC_02782 220668.lp_0311 1.4e-77 295.4 Lactobacillaceae elaA GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 ko:K02348 ko00000 Bacteria 1VAJY@1239,3F5B8@33958,4HIH7@91061,COG2153@1,COG2153@2 NA|NA|NA S GNAT family PGHMIELC_02783 220668.lp_0312 1.7e-75 288.5 Lactobacillaceae Bacteria 1V3PS@1239,3F6VT@33958,4HFN6@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator PGHMIELC_02784 220668.lp_0313 7.8e-227 792.7 Lactobacillaceae ndh GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 1.6.99.3 ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1TR6X@1239,3F4N1@33958,4HA14@91061,COG1252@1,COG1252@2 NA|NA|NA C NADH dehydrogenase PGHMIELC_02785 220668.lp_0314 2.6e-37 161.0 Lactobacillaceae Bacteria 1U6R1@1239,29C9K@1,2ZZ83@2,3F8C8@33958,4IGIB@91061 NA|NA|NA PGHMIELC_02786 1487921.DP68_09175 2.5e-08 65.1 Clostridia Bacteria 1VGVV@1239,24TYK@186801,2ED2P@1,336ZK@2 NA|NA|NA S Motility quorum-sensing regulator, toxin of MqsA PGHMIELC_02787 1423807.BACO01000061_gene1763 2.2e-30 139.0 Lactobacillaceae Bacteria 1UFFJ@1239,29UVW@1,30G8B@2,3F7VN@33958,4IEQ7@91061 NA|NA|NA PGHMIELC_02788 1423754.BALY01000009_gene72 7.1e-21 107.1 Lactobacillaceae ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03110 3.A.5 Bacteria 1U778@1239,3F929@33958,4IH20@91061,COG1952@1,COG1952@2 NA|NA|NA U Preprotein translocase subunit SecB PGHMIELC_02789 220668.lp_0315 4e-206 723.8 Lactobacillaceae potD ko:K11069 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 iSB619.SA_RS05395 Bacteria 1TPY1@1239,3F3W1@33958,4HAET@91061,COG0687@1,COG0687@2 NA|NA|NA P ABC transporter PGHMIELC_02790 220668.lp_0316 3.4e-141 507.7 Lactobacillaceae potC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008519,GO:0015075,GO:0015101,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015595,GO:0015606,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072488,GO:0098533,GO:0098655,GO:0098796,GO:0098797,GO:1902047,GO:1902494,GO:1902495,GO:1903711,GO:1904949,GO:1990351 ko:K11070 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 iSBO_1134.SBO_1939 Bacteria 1V0VD@1239,3F3ZN@33958,4H9ZC@91061,COG1177@1,COG1177@2 NA|NA|NA P ABC transporter permease PGHMIELC_02791 220668.lp_0317 2.7e-149 534.6 Lactobacillaceae potB ko:K11071 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 Bacteria 1TQ7Z@1239,3F4CM@33958,4HAYS@91061,COG1176@1,COG1176@2 NA|NA|NA P ABC transporter permease PGHMIELC_02792 220668.lp_0318 3.5e-205 720.7 Lactobacillaceae potA 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 iSB619.SA_RS05380 Bacteria 1TP2M@1239,3F40H@33958,4H9MS@91061,COG3842@1,COG3842@2 NA|NA|NA P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system PGHMIELC_02793 220668.lp_0319 3.8e-96 357.5 Lactobacillaceae puuR Bacteria 1V1K5@1239,3F5FE@33958,4HGGY@91061,COG1396@1,COG1396@2 NA|NA|NA K Cupin domain PGHMIELC_02794 220668.lp_0320 1.1e-83 315.8 Lactobacillaceae 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 Bacteria 1V6S0@1239,3F7EV@33958,4HKKR@91061,COG4405@1,COG4405@2 NA|NA|NA S ASCH PGHMIELC_02795 220668.lp_0321 1e-84 319.3 Lactobacillaceae ko:K03830 ko00000,ko01000 Bacteria 1V6S5@1239,3F6HM@33958,4HJJY@91061,COG0454@1,COG0456@2 NA|NA|NA K GNAT family PGHMIELC_02796 220668.lp_0322 2.6e-89 334.7 Lactobacillaceae Bacteria 1UIXA@1239,3F70D@33958,4ISVN@91061,COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase PGHMIELC_02797 220668.lp_0324 8.1e-22 109.0 Lactobacillaceae Bacteria 1U6TW@1239,29PNG@1,30AKP@2,3F8HB@33958,4IGMQ@91061 NA|NA|NA PGHMIELC_02798 220668.lp_0325 1.4e-59 235.3 Lactobacillaceae ytrA ko:K07978,ko:K07979 ko00000,ko03000 Bacteria 1VFD0@1239,3F70C@33958,4I3PG@91061,COG1725@1,COG1725@2 NA|NA|NA K helix_turn_helix gluconate operon transcriptional repressor PGHMIELC_02799 220668.lp_0326 2e-163 581.6 Lactobacillaceae ytrB ko:K01990,ko:K16921 ko02010,map02010 M00254,M00584 ko00000,ko00001,ko00002,ko02000 3.A.1 Bacteria 1TPQW@1239,3FC3A@33958,4HA3P@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter PGHMIELC_02800 220668.lp_0327 3.2e-189 667.5 Lactobacillaceae Bacteria 1U5IP@1239,29NSX@1,309QZ@2,3F61I@33958,4IF9F@91061 NA|NA|NA PGHMIELC_02801 220668.lp_0329 1.1e-256 892.1 Lactobacillaceae adhE 1.1.1.1,1.2.1.10 ko:K00001,ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00228,R00623,R00754,R01172,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00004,RC00050,RC00087,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1UHQT@1239,3F5S5@33958,4IS6J@91061,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family PGHMIELC_02802 220668.lp_0330 2.8e-162 577.8 Lactobacillaceae fba 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ01@1239,3F4EF@33958,4H9ZU@91061,COG0191@1,COG0191@2 NA|NA|NA G Fructose-1,6-bisphosphate aldolase, class II PGHMIELC_02803 525318.HMPREF0497_1784 2.4e-300 1037.3 Lactobacillaceae ybeC Bacteria 1TPJH@1239,3F4AR@33958,4HC13@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid PGHMIELC_02804 1302286.BAOT01000085_gene2226 1.3e-193 682.2 Lactobacillaceae Bacteria 1TRSF@1239,3F3YG@33958,4HADR@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family PGHMIELC_02805 1423807.BACO01000054_gene1626 5.9e-103 380.2 Lactobacillaceae tnpR Bacteria 1UZM8@1239,3FBG8@33958,4IQ67@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain PGHMIELC_02806 1074451.CRL705_1078 6.1e-40 170.2 Bacilli Bacteria 1VD11@1239,2DAFF@1,32TVB@2,4HMK7@91061 NA|NA|NA PGHMIELC_02807 1138822.PL11_10125 0.0 1829.3 Lactobacillaceae Bacteria 1TRZH@1239,3F4XU@33958,4HE9W@91061,COG1002@1,COG1002@2 NA|NA|NA V Type II restriction enzyme, methylase subunits PGHMIELC_02808 1138822.PL11_10130 8.9e-41 172.6 Lactobacillaceae Bacteria 1UN9D@1239,3FBZ4@33958,4IU8A@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix domain PGHMIELC_02809 1138822.PL11_10135 2.8e-63 247.7 Lactobacillaceae GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0045926,GO:0045927,GO:0046483,GO:0048518,GO:0048519,GO:0050789,GO:0050896,GO:0065007,GO:0070482,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 Bacteria 1VB8K@1239,3F7HF@33958,4HKT7@91061,COG4679@1,COG4679@2 NA|NA|NA S Phage derived protein Gp49-like (DUF891) PGHMIELC_02811 908339.HMPREF9265_2091 3e-15 87.4 Lactobacillaceae ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1825,iSB619.SA_RS08940,iSFV_1184.SFV_0380 Bacteria 1V1DA@1239,3F70X@33958,4HFRA@91061,COG0054@1,COG0054@2 NA|NA|NA H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin PGHMIELC_02812 944562.HMPREF9102_1894 1.6e-176 625.5 Lactobacillaceae ribBA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS10830,iSB619.SA_RS08945 Bacteria 1TPH9@1239,3F4EB@33958,4H9PW@91061,COG0108@1,COG0108@2,COG0807@1,COG0807@2 NA|NA|NA H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate PGHMIELC_02813 557436.Lreu_1010 2e-72 278.9 Lactobacillaceae Bacteria 1TQST@1239,3F47D@33958,4HPQC@91061,COG4974@1,COG4974@2 NA|NA|NA L Transposase IS66 family PGHMIELC_02814 1302286.BAOT01000025_gene1258 1.1e-144 520.0 Lactobacillaceae Bacteria 1V192@1239,3F5GG@33958,4IJ3S@91061,COG0846@1,COG0846@2 NA|NA|NA K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form PGHMIELC_02815 326425.lhe_1116 1.3e-101 376.3 Lactobacillaceae Bacteria 1TQB7@1239,3F4Q7@33958,4HAQT@91061,COG0846@1,COG0846@2 NA|NA|NA K COG COG0846 NAD-dependent protein deacetylases, SIR2 family PGHMIELC_02816 334390.LAF_1781 8.5e-159 566.2 Lactobacillaceae Bacteria 1TRSF@1239,3F4DZ@33958,4HCMP@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair PGHMIELC_02817 1033837.WANG_0646 1.1e-61 243.0 Lactobacillaceae Bacteria 1V6JC@1239,3F58C@33958,4IF0F@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family PGHMIELC_02818 1235801.C822_01952 8.5e-76 289.7 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3F59Y@33958,4HBHG@91061,COG2801@1,COG2801@2 NA|NA|NA L PFAM Integrase catalytic region PGHMIELC_02819 1133569.AHYZ01000017_gene1019 1.8e-128 465.3 Lactobacillaceae Bacteria 1TQN4@1239,3F5I0@33958,4HKTX@91061,COG4227@1,COG4227@2 NA|NA|NA L Psort location Cytoplasmic, score PGHMIELC_02820 1136177.KCA1_2798 3.8e-31 140.2 Lactobacillaceae copZ ko:K07213 ko04978,map04978 ko00000,ko00001 Bacteria 1VFJ8@1239,3F830@33958,4HNY2@91061,COG2608@1,COG2608@2 NA|NA|NA P Heavy-metal-associated domain PGHMIELC_02821 1136177.KCA1_2797 2.5e-95 354.8 Lactobacillaceae dps ko:K04047 ko00000,ko03036 Bacteria 1VB1X@1239,3F4SN@33958,4HMJG@91061,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family PGHMIELC_02822 60520.HR47_11385 3.8e-17 93.6 Lactobacillaceae Bacteria 1U6GC@1239,29PE2@1,30AC8@2,3F7V0@33958,4IG8G@91061 NA|NA|NA PGHMIELC_02823 1136177.KCA1_2795 1.1e-38 165.6 Lactobacillaceae yrkD Bacteria 1VFB9@1239,3F74Z@33958,4HNVQ@91061,COG1937@1,COG1937@2 NA|NA|NA S Metal-sensitive transcriptional repressor PGHMIELC_02824 1136177.KCA1_2794 2.1e-54 218.0 Lactobacillaceae txlA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 iAPECO1_1312.trxA Bacteria 1UI60@1239,3F6Q0@33958,4ISEX@91061,COG0526@1,COG0526@2 NA|NA|NA O Thioredoxin-like domain PGHMIELC_02825 1114972.AUAW01000009_gene2133 3.5e-08 65.1 Lactobacillaceae Bacteria 1U72Q@1239,29PUY@1,30AT5@2,3F8WD@33958,4IGX9@91061 NA|NA|NA S Enterocin A Immunity PGHMIELC_02826 1136177.KCA1_2793 4.1e-141 507.3 Lactobacillaceae glpF ko:K02440 ko00000,ko02000 1.A.8.1,1.A.8.2 Bacteria 1TP4T@1239,3F4J6@33958,4HAWP@91061,COG0580@1,COG0580@2 NA|NA|NA U Belongs to the MIP aquaporin (TC 1.A.8) family PGHMIELC_02827 1136177.KCA1_2792 0.0 1161.0 Lactobacillaceae cadA 3.6.3.3,3.6.3.5 ko:K01534 ko00000,ko01000 3.A.3.6 Bacteria 1TQ07@1239,3F4T3@33958,4H9SP@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase PGHMIELC_02829 1138822.PL11_10600 2.4e-56 224.6 Lactobacillaceae Bacteria 1TX67@1239,2A0U1@1,30NYT@2,3F6CW@33958,4I62R@91061 NA|NA|NA PGHMIELC_02830 1045004.OKIT_1876 3e-99 367.9 Leuconostocaceae ko:K04763 ko00000,ko03036 Bacteria 1V2RX@1239,4AZ3V@81850,4HG5J@91061,COG0582@1,COG0582@2 NA|NA|NA L Integrase PGHMIELC_02831 1122149.BACN01000100_gene1980 1.7e-44 184.9 Lactobacillaceae yefM 2.3.1.15 ko:K08591,ko:K19158,ko:K19159 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004,ko02048 Bacteria 1U6CD@1239,3F7KJ@33958,4IG41@91061,COG2161@1,COG2161@2 NA|NA|NA D Antitoxin component of a toxin-antitoxin (TA) module PGHMIELC_02832 46256.BBIK01000013_gene1706 5.4e-59 233.4 Bacteria yafQ GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006415,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032984,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034655,GO:0042221,GO:0042710,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043565,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044010,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044764,GO:0044877,GO:0046483,GO:0046677,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 ko:K19157 ko00000,ko01000,ko02048 Bacteria COG3041@1,COG3041@2 NA|NA|NA S endonuclease activity PGHMIELC_02834 1074451.CRL705_1934 1.7e-84 318.5 Lactobacillaceae dps ko:K04047 ko00000,ko03036 Bacteria 1VCVJ@1239,3F5WI@33958,4HMBD@91061,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family PGHMIELC_02835 1423734.JCM14202_2822 1.8e-133 481.9 Lactobacillaceae ko:K01990,ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQKM@1239,3F3VV@33958,4HBUK@91061,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system PGHMIELC_02836 1027396.LMOSA_9200 4e-19 100.9 Firmicutes 3.4.21.88 ko:K01356 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 1VK84@1239,COG1396@1,COG1396@2 NA|NA|NA K Transcriptional PGHMIELC_02838 1163671.JAGI01000002_gene2857 2.4e-08 64.7 Clostridiaceae Bacteria 1V4N6@1239,24JDG@186801,36JH7@31979,COG2856@1,COG2856@2 NA|NA|NA E Zn peptidase PGHMIELC_02839 1329250.WOSG25_250010 8.1e-24 118.2 Bacilli Bacteria 1VMBZ@1239,2EH4Z@1,33AWV@2,4HSE4@91061 NA|NA|NA S Short C-terminal domain PGHMIELC_02840 12417.O48432_9CAUD 1.4e-21 110.5 Caudovirales Viruses 4QGUV@10239,4QRVU@28883,4QX37@35237 NA|NA|NA S Short C-terminal domain PGHMIELC_02842 1074451.CRL705_1763 1.4e-97 362.8 Lactobacillaceae Bacteria 1TPVP@1239,28HAW@1,2Z7N4@2,3F8KG@33958,4HEJS@91061 NA|NA|NA S KilA-N domain PGHMIELC_02844 220668.lp_0624 3.8e-93 348.6 Lactobacillaceae Bacteria 1VJ2V@1239,3F4UK@33958,4HPCG@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family PGHMIELC_02845 748671.LCRIS_00063 1.5e-42 178.7 Lactobacillaceae Bacteria 1VB4V@1239,2DX7X@1,32V2Y@2,3F76M@33958,4HKWS@91061 NA|NA|NA S COG NOG38524 non supervised orthologous group PGHMIELC_02855 1122149.BACN01000053_gene48 5.5e-08 62.0 Lactobacillaceae Bacteria 1U76W@1239,2DIA5@1,302HX@2,3F91Y@33958,4IH1Q@91061 NA|NA|NA PGHMIELC_02865 1074451.CRL705_1940 9.2e-71 272.7 Lactobacillaceae Bacteria 1TRSF@1239,3F4DZ@33958,4HCMP@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair PGHMIELC_02866 220668.lp_0331 2.3e-240 837.8 Lactobacillaceae xylP1 ko:K03292,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.2 Bacteria 1TRA5@1239,3F3UZ@33958,4HBAI@91061,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein PGHMIELC_02867 220668.lp_0332 3e-122 444.9 Lactobacillaceae qmcA GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 Bacteria 1TPXU@1239,3F4HV@33958,4HGRC@91061,COG0330@1,COG0330@2 NA|NA|NA O prohibitin homologues PGHMIELC_02868 220668.lp_0333 1.5e-29 134.8 Lactobacillaceae Bacteria 1U6GJ@1239,2DKQN@1,30ACH@2,3F7VP@33958,4IG8R@91061 NA|NA|NA PGHMIELC_02869 220668.lp_0334 5e-281 973.0 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase PGHMIELC_02870 220668.lp_0335 3e-40 170.6 Lactobacillaceae Bacteria 1USWD@1239,2930D@1,3270J@2,3F7S4@33958,4IG6X@91061 NA|NA|NA PGHMIELC_02871 220668.lp_0336 6.8e-96 356.7 Lactobacillaceae bioY GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 ko:K03523 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 Bacteria 1VAAD@1239,3F6YG@33958,4HI8T@91061,COG1268@1,COG1268@2 NA|NA|NA S BioY family PGHMIELC_02872 220668.lp_0337 2.7e-177 627.9 Lactobacillaceae birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 ko:K03524,ko:K04096 ko00780,ko01100,map00780,map01100 R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 Bacteria 1TQCU@1239,3F5HY@33958,4HB60@91061,COG0340@1,COG0340@2,COG1654@1,COG1654@2 NA|NA|NA H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor PGHMIELC_02873 220668.lp_0338 1.9e-60 238.0 Lactobacillaceae Bacteria 1VB64@1239,3F8FS@33958,4HMGX@91061,COG4357@1,COG4357@2 NA|NA|NA S CHY zinc finger PGHMIELC_02874 220668.lp_0339 6.3e-224 783.1 Lactobacillaceae mtnE 2.6.1.83 ko:K08969,ko:K10206 ko00270,ko00300,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map01100,map01110,map01130,map01230 M00034,M00527 R07396,R07613 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TQD6@1239,3F4TW@33958,4HAHQ@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase PGHMIELC_02875 220668.lp_0340 2.2e-218 764.6 Lactobacillaceae Bacteria 1U598@1239,2CC2J@1,309K5@2,3F58S@33958,4IF0I@91061 NA|NA|NA PGHMIELC_02876 220668.lp_0343 3.5e-154 550.8 Lactobacillaceae tagG GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015920,GO:0033036,GO:0051179,GO:0051234,GO:0071702,GO:1901264 ko:K09690,ko:K09692 ko02010,map02010 M00250,M00251 ko00000,ko00001,ko00002,ko02000 3.A.1.103,3.A.1.104 Bacteria 1TQZF@1239,3F4FP@33958,4HB9R@91061,COG1682@1,COG1682@2 NA|NA|NA U Transport permease protein PGHMIELC_02877 220668.lp_0344 1e-201 709.1 Lactobacillaceae tagH 3.6.3.38,3.6.3.40 ko:K09689,ko:K09693 ko02010,map02010 M00249,M00251 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.101,3.A.1.104 Bacteria 1TQKK@1239,3F4V6@33958,4HC6N@91061,COG1134@1,COG1134@2 NA|NA|NA GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system PGHMIELC_02878 220668.lp_0346 3.8e-44 183.7 Lactobacillaceae Bacteria 1U69T@1239,29P8S@1,30A6W@2,3F7E4@33958,4IG0Y@91061 NA|NA|NA PGHMIELC_02879 220668.lp_0347 3.9e-93 347.4 Lactobacillaceae Bacteria 1VEN3@1239,3F6IE@33958,4HS7A@91061,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family PGHMIELC_02880 220668.lp_0348 2.1e-258 897.9 Lactobacillaceae Bacteria 1UNMW@1239,3FBTN@33958,4ISTJ@91061,COG0477@1,COG0477@2,COG2211@1,COG2211@2 NA|NA|NA P Major Facilitator Superfamily PGHMIELC_02881 220668.lp_0349 2.5e-242 844.3 Lactobacillaceae amtB ko:K03320 ko00000,ko02000 1.A.11 Bacteria 1TQYG@1239,3F3X1@33958,4HBGK@91061,COG0004@1,COG0004@2 NA|NA|NA P ammonium transporter PGHMIELC_02882 220668.lp_0350 7.5e-180 636.3 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1UXY2@1239,3F4M2@33958,4HD1S@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily PGHMIELC_02883 220668.lp_0351 3.7e-44 183.7 Lactobacillaceae Bacteria 1U6B9@1239,2A5G1@1,30U62@2,3F7HZ@33958,4IG2T@91061 NA|NA|NA PGHMIELC_02884 220668.lp_0353 6.3e-102 376.7 Lactobacillaceae zmp1 Bacteria 1UGZG@1239,3F627@33958,4IF9R@91061,COG5549@1,COG5549@2 NA|NA|NA O Zinc-dependent metalloprotease PGHMIELC_02885 220668.lp_0354 2.3e-119 434.9 Lactobacillaceae rpiA GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 iJN678.rpiA Bacteria 1V22S@1239,3FC6F@33958,4HFWX@91061,COG0120@1,COG0120@2 NA|NA|NA G Ribose 5-phosphate isomerase A (phosphoriboisomerase A) PGHMIELC_02886 220668.lp_0355 3.1e-310 1070.1 Lactobacillaceae mco Bacteria 1TQSU@1239,3F3XB@33958,4HDD6@91061,COG2132@1,COG2132@2 NA|NA|NA Q Multicopper oxidase PGHMIELC_02887 220668.lp_0357 3.2e-54 217.6 Lactobacillaceae ypaA ko:K08987 ko00000 Bacteria 1VAVU@1239,3F7NA@33958,4HQHN@91061,COG3759@1,COG3759@2 NA|NA|NA S Protein of unknown function (DUF1304) PGHMIELC_02888 220668.lp_0358 8.8e-95 352.8 Lactobacillaceae yxkA ko:K06910 ko00000 Bacteria 1VJEE@1239,3F75J@33958,4HXTJ@91061,COG1881@1,COG1881@2 NA|NA|NA S Phosphatidylethanolamine-binding protein PGHMIELC_02889 220668.lp_0359 1.1e-231 808.9 Lactobacillaceae flhF ko:K02404,ko:K09384 ko00000,ko02035 Bacteria 1TPQU@1239,3F47M@33958,4HBI0@91061,COG1419@1,COG1419@2,COG3410@1,COG3410@2 NA|NA|NA N Uncharacterized conserved protein (DUF2075) PGHMIELC_02890 220668.lp_0360 9.3e-83 312.8 Lactobacillaceae ywnA ko:K19587 M00767 ko00000,ko00002,ko03000 Bacteria 1U353@1239,3F58B@33958,4ICW0@91061,COG1959@1,COG1959@2 NA|NA|NA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding PGHMIELC_02891 220668.lp_0361 9.3e-80 302.8 Lactobacillaceae Bacteria 1U62U@1239,29P3G@1,30A1P@2,3F6WC@33958,4IFRZ@91061 NA|NA|NA PGHMIELC_02892 220668.lp_0362 1.4e-69 269.2 Lactobacillaceae accB 2.3.1.12 ko:K00627,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TWUA@1239,3F5YZ@33958,4I5NI@91061,COG0511@1,COG0511@2 NA|NA|NA I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA PGHMIELC_02893 60520.HR47_09085 7.7e-174 616.3 Lactobacillaceae rihC 3.2.2.1 ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 Bacteria 1TSSS@1239,3F4T0@33958,4HB17@91061,COG1957@1,COG1957@2 NA|NA|NA F Nucleoside PGHMIELC_02894 220668.lp_0364 3e-162 577.8 Lactobacillaceae vdlC Bacteria 1UHN7@1239,3F5A5@33958,4IS46@91061,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family PGHMIELC_02895 220668.lp_0367 1.8e-276 958.0 Lactobacillaceae proWX ko:K05845,ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1TQ7D@1239,3F44S@33958,4HBDR@91061,COG1174@1,COG1174@2,COG1732@1,COG1732@2 NA|NA|NA EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) PGHMIELC_02896 220668.lp_0368 9.9e-180 636.0 Lactobacillaceae proV ko:K05847 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1TPV8@1239,3F55H@33958,4H9SI@91061,COG1125@1,COG1125@2 NA|NA|NA E ABC transporter, ATP-binding protein PGHMIELC_02897 220668.lp_0369 2.6e-255 887.5 Lactobacillaceae gshR 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1TS0Z@1239,3F3K2@33958,4HBYB@91061,COG1249@1,COG1249@2 NA|NA|NA C Glutathione reductase PGHMIELC_02898 220668.lp_0370 1.3e-300 1038.1 Lactobacillaceae glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPX3@1239,3F3WI@33958,4H9ZF@91061,COG0554@1,COG0554@2 NA|NA|NA F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate PGHMIELC_02899 220668.lp_0371 0.0 1197.6 Lactobacillaceae glpD 1.1.3.21,1.1.5.3 ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 R00846,R00848 RC00029 ko00000,ko00001,ko01000 Bacteria 1TQJN@1239,3F5BS@33958,4HAG8@91061,COG0578@1,COG0578@2 NA|NA|NA C C-terminal domain of alpha-glycerophosphate oxidase PGHMIELC_02900 220668.lp_0372 3e-133 481.1 Lactobacillaceae glpF ko:K02440,ko:K06188 ko00000,ko02000 1.A.8,1.A.8.1,1.A.8.2 Bacteria 1TP4T@1239,3F4J6@33958,4HAWP@91061,COG0580@1,COG0580@2 NA|NA|NA U Belongs to the MIP aquaporin (TC 1.A.8) family PGHMIELC_02901 220668.lp_0373 0.0 1659.8 Lactobacillaceae Bacteria 1UV28@1239,3F7MP@33958,4HWU5@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein PGHMIELC_02902 220668.lp_0374 3.4e-32 146.7 Bacteria Bacteria COG1091@1,COG1091@2 NA|NA|NA M dTDP-4-dehydrorhamnose reductase activity PGHMIELC_02903 220668.lp_0379 1.4e-175 622.1 Lactobacillaceae Bacteria 1UUT4@1239,2BF1Z@1,328TX@2,3F9UD@33958,4IHH1@91061 NA|NA|NA PGHMIELC_02904 220668.lp_0376 6.5e-33 146.4 Lactobacillaceae Bacteria 1U84J@1239,29QHX@1,30BHD@2,3FAIP@33958,4II20@91061 NA|NA|NA PGHMIELC_02905 220668.lp_0391 1.7e-39 168.3 Lactobacillaceae Bacteria 1U7SF@1239,29QHX@1,30B9Q@2,3FA3Y@33958,4IHPT@91061 NA|NA|NA PGHMIELC_02906 220668.lp_0385 1.2e-64 252.3 Bacilli Bacteria 1VQEB@1239,2EG2D@1,339UD@2,4HXG9@91061 NA|NA|NA PGHMIELC_02907 220668.lp_0388 5.6e-68 263.5 Firmicutes Bacteria 1VQHD@1239,2E8X6@1,33378@2 NA|NA|NA S Immunity protein 63 PGHMIELC_02908 220668.lp_0377 2.4e-38 164.5 Lactobacillaceae Bacteria 1U7SF@1239,29QHX@1,30B9Q@2,3FA3Y@33958,4IHPT@91061 NA|NA|NA PGHMIELC_02909 220668.lp_0393 9.6e-120 436.0 Lactobacillaceae lacA 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 ko00000,ko01000 Bacteria 1TQQB@1239,3FC9A@33958,4HG1G@91061,COG0110@1,COG0110@2 NA|NA|NA S Maltose acetyltransferase PGHMIELC_02910 220668.lp_0394 4.8e-197 693.7 Lactobacillaceae uhpT Bacteria 1TQZ7@1239,3F54C@33958,4HERG@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_02911 220668.lp_0395 6.9e-147 526.6 Lactobacillaceae 3.1.3.102,3.1.3.104 ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1UYU8@1239,3F3ZW@33958,4HE0K@91061,COG0561@1,COG0561@2 NA|NA|NA G Sucrose-6F-phosphate phosphohydrolase PGHMIELC_02912 220668.lp_0396 3.3e-166 590.9 Lactobacillaceae ko:K03490 ko00000,ko03000 Bacteria 1TVGS@1239,3F5KS@33958,4I2JI@91061,COG1917@1,COG1917@2,COG2207@1,COG2207@2 NA|NA|NA K Transcriptional regulator PGHMIELC_02913 220668.lp_0397 1.4e-150 538.9 Lactobacillaceae Bacteria 1TR16@1239,3F55S@33958,4HCZ6@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase PGHMIELC_02914 220668.lp_0399 3.2e-256 890.6 Lactobacillaceae brnQ GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 ko:K03311 ko00000 2.A.26 Bacteria 1TQIS@1239,3F3KC@33958,4HAKA@91061,COG1114@1,COG1114@2 NA|NA|NA U Component of the transport system for branched-chain amino acids PGHMIELC_02915 220668.lp_0400 2.1e-208 731.5 Lactobacillaceae napA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 Bacteria 1TS32@1239,3F3QK@33958,4HAGC@91061,COG0475@1,COG0475@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family PGHMIELC_02917 220668.lp_0402 7.2e-32 142.5 Lactobacillaceae Bacteria 1U75A@1239,29PWX@1,30AV8@2,3F8ZZ@33958,4IGZZ@91061 NA|NA|NA PGHMIELC_02918 220668.lp_0403 2.9e-17 93.6 Lactobacillaceae plnR Bacteria 1U8C2@1239,2BSTZ@1,32MXF@2,3FATJ@33958,4IIA1@91061 NA|NA|NA PGHMIELC_02919 220668.lp_0404 1.7e-117 428.7 Lactobacillaceae Bacteria 1U6V7@1239,2CBER@1,30AMI@2,3F8J9@33958,4IGP3@91061 NA|NA|NA PGHMIELC_02920 220668.lp_0405 5.2e-23 112.8 Lactobacillaceae plnK Bacteria 1U7YQ@1239,29QE9@1,30BDK@2,3FABZ@33958,4IHW4@91061 NA|NA|NA PGHMIELC_02921 220668.lp_0406 3.5e-24 116.7 Lactobacillaceae plnJ Bacteria 1U80K@1239,29QFH@1,30BEW@2,3FADY@33958,4IHXZ@91061 NA|NA|NA PGHMIELC_02922 220668.lp_0409 2.8e-28 130.6 Lactobacillaceae Bacteria 1U6ZA@1239,2DKT4@1,30AQB@2,3F8RH@33958,4IGTJ@91061 NA|NA|NA PGHMIELC_02924 220668.lp_0411 3.9e-226 790.4 Lactobacillaceae GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009403,GO:0009404,GO:0009987,GO:0016740,GO:0016757,GO:0016999,GO:0017000,GO:0017144,GO:0018193,GO:0018198,GO:0018240,GO:0018280,GO:0019538,GO:0019748,GO:0030152,GO:0030650,GO:0030651,GO:0034641,GO:0034645,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043413,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044550,GO:0046224,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 Bacteria 1UV29@1239,3F8S5@33958,4I29G@91061,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 PGHMIELC_02925 220668.lp_0412 7e-117 426.8 Lactobacillaceae plnP ko:K07052 ko00000 Bacteria 1U5JH@1239,3F637@33958,4IFAB@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity PGHMIELC_02926 220668.lp_0413 8.4e-27 125.6 Lactobacillaceae Bacteria 1U7XW@1239,29QDU@1,30BD4@2,3FAB1@33958,4IHV9@91061 NA|NA|NA PGHMIELC_02927 220668.lp_0415 2.1e-17 94.0 Lactobacillaceae plnA Bacteria 1U8CY@1239,2BT43@1,32N8N@2,3FAUJ@33958,4IIAX@91061 NA|NA|NA PGHMIELC_02928 220668.lp_0416 1e-235 822.4 Lactobacillaceae plnB 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1V1ET@1239,3F71I@33958,4HGNA@91061,COG3290@1,COG3290@2 NA|NA|NA T GHKL domain PGHMIELC_02929 220668.lp_0417 9.1e-133 479.6 Lactobacillaceae plnC ko:K07707 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko02022 Bacteria 1V392@1239,3F5PZ@33958,4HHAI@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain PGHMIELC_02930 220668.lp_0418 3.7e-134 484.2 Lactobacillaceae plnD ko:K07707 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko02022 Bacteria 1V392@1239,3F52U@33958,4HHAI@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain PGHMIELC_02931 220668.lp_0419 2.2e-129 468.4 Lactobacillaceae ko:K07052 ko00000 Bacteria 1W74B@1239,3F93M@33958,4IH2Z@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity PGHMIELC_02932 220668.lp_0421 2.4e-22 110.5 Lactobacillaceae plnF Bacteria 1U7ZG@1239,29QER@1,30BE3@2,3FACU@33958,4IHWW@91061 NA|NA|NA PGHMIELC_02933 220668.lp_0422 6.7e-23 112.5 Lactobacillaceae Bacteria 1U7YI@1239,2BIA2@1,32CFN@2,3FABR@33958,4IHVW@91061 NA|NA|NA PGHMIELC_02934 220668.lp_0423 0.0 1357.0 Lactobacillaceae comA GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.112.1,3.A.1.21 Bacteria 1V77J@1239,3F3QF@33958,4HAX2@91061,COG2274@1,COG2274@2 NA|NA|NA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain PGHMIELC_02935 220668.lp_0424 1.4e-243 848.6 Lactobacillaceae mesE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 3.A.1.112,8.A.1,8.A.1.4.2 Bacteria 1V5C8@1239,3F5W4@33958,4HHKB@91061,COG0845@1,COG0845@2 NA|NA|NA M Transport protein ComB PGHMIELC_02936 220668.lp_0425 2.1e-94 351.7 Lactobacillaceae ko:K07052 ko00000 Bacteria 1U7E2@1239,3F9G8@33958,4IH9Y@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity PGHMIELC_02937 220668.lp_0426 1.6e-120 438.7 Lactobacillaceae ypbD ko:K07052 ko00000 Bacteria 1W74A@1239,3F750@33958,4IFVR@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity PGHMIELC_02938 220668.lp_0428 4.7e-112 410.6 Bacteria ko:K07052 ko00000 Bacteria COG1266@1,COG1266@2 NA|NA|NA V CAAX protease self-immunity PGHMIELC_02939 220668.lp_0429 1e-114 419.5 Lactobacillaceae ko:K07052 ko00000 Bacteria 1U6ES@1239,3F7RC@33958,4IG6J@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity PGHMIELC_02940 60520.HR47_08895 2.6e-29 134.0 Lactobacillaceae Bacteria 1U75A@1239,29PWX@1,30AV8@2,3F8ZZ@33958,4IGZZ@91061 NA|NA|NA PGHMIELC_02941 220668.lp_0432 0.0 1447.6 Lactobacillaceae helD 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP39@1239,3F486@33958,4H9Y5@91061,COG3973@1,COG3973@2 NA|NA|NA L DNA helicase PGHMIELC_02942 60520.HR47_08885 1.2e-140 505.8 Lactobacillaceae mtnU 3.5.1.3 ko:K11206,ko:K13566 ko00250,map00250 R00269,R00348 RC00010 ko00000,ko00001,ko01000 Bacteria 1TQDK@1239,3F4ND@33958,4HC44@91061,COG0388@1,COG0388@2 NA|NA|NA S Carbon-nitrogen hydrolase PGHMIELC_02943 220668.lp_0434 2.6e-191 674.5 Lactobacillaceae trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPY7@1239,3F3V6@33958,4HA1K@91061,COG0180@1,COG0180@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family PGHMIELC_02944 220668.lp_0435 9e-130 469.5 Lactobacillaceae ko:K03489,ko:K03710,ko:K11922 ko00000,ko03000 Bacteria 1TTCD@1239,3F4DA@33958,4HEXQ@91061,COG2188@1,COG2188@2 NA|NA|NA K UbiC transcription regulator-associated domain protein PGHMIELC_02945 220668.lp_0436 1.9e-253 881.3 Lactobacillaceae celB GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264,GO:1902815 ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 iECABU_c1320.ECABU_c19930 Bacteria 1TP8D@1239,3F4VG@33958,4H9W2@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane PGHMIELC_02946 60520.HR47_08865 3.9e-24 116.7 Lactobacillaceae Bacteria 1U81V@1239,29QG9@1,30BFQ@2,3FAF9@33958,4IHZ8@91061 NA|NA|NA PGHMIELC_02947 220668.lp_0438 2.6e-76 291.2 Lactobacillaceae Bacteria 1VEZ0@1239,2DQNY@1,337UX@2,3F69F@33958,4HPE2@91061 NA|NA|NA S Domain of unknown function (DUF3284) PGHMIELC_02948 220668.lp_0439 1.5e-250 871.7 Lactobacillaceae chbC ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 Bacteria 1TP8D@1239,3F4VG@33958,4H9W2@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane PGHMIELC_02949 220668.lp_0440 7.3e-296 1022.3 Lactobacillaceae celA 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family PGHMIELC_02950 220668.lp_0441 1e-162 579.3 Lactobacillaceae Bacteria 1V20R@1239,3F60F@33958,4HFXJ@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family PGHMIELC_02951 220668.lp_0442 4.1e-133 480.7 Lactobacillaceae Bacteria 1V5JY@1239,3FC4E@33958,4HI0D@91061,COG1737@1,COG1737@2 NA|NA|NA K Helix-turn-helix domain, rpiR family PGHMIELC_02952 220668.lp_0443 8.1e-191 672.9 Lactobacillaceae dus ko:K05541 ko00000,ko01000,ko03016 Bacteria 1TQ2R@1239,3F4D2@33958,4HA9K@91061,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines PGHMIELC_02953 220668.lp_0444 1.1e-206 725.7 Lactobacillaceae Bacteria 1U7MT@1239,29Q7M@1,30B6N@2,3F9X7@33958,4IHJ1@91061 NA|NA|NA PGHMIELC_02954 220668.lp_0445 3.5e-151 540.8 Lactobacillaceae Bacteria 1V2P2@1239,28JTN@1,2Z9IV@2,3F9JV@33958,4I4SN@91061 NA|NA|NA S Psort location Cytoplasmic, score PGHMIELC_02955 220668.lp_0446 8.2e-168 596.3 Lactobacillaceae ppx 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 1TS3I@1239,3F3SR@33958,4HAQS@91061,COG0248@1,COG0248@2 NA|NA|NA FP exopolyphosphatase PGHMIELC_02956 220668.lp_0447 4e-229 800.4 Lactobacillaceae mvaA 1.1.1.34,1.1.1.88,2.3.1.9 ko:K00021,ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,ko04152,ko04976,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020,map04152,map04976 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081,R02082 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TPNY@1239,3F3YY@33958,4HBQ3@91061,COG1257@1,COG1257@2 NA|NA|NA C Belongs to the HMG-CoA reductase family PGHMIELC_02957 220668.lp_0448 3.1e-178 630.9 Lactobacillaceae Bacteria 1VT7R@1239,296WI@1,2ZU5A@2,3F4R1@33958,4HVBN@91061 NA|NA|NA PGHMIELC_02958 220668.lp_0449 8.6e-133 479.6 Lactobacillaceae cobB ko:K12410 ko00000,ko01000 Bacteria 1TQKD@1239,3F4WS@33958,4HC4I@91061,COG0846@1,COG0846@2 NA|NA|NA K SIR2 family PGHMIELC_02959 220668.lp_0450 2e-160 571.6 Lactobacillaceae yunF Bacteria 1TPX4@1239,3F40Y@33958,4HA0X@91061,COG1801@1,COG1801@2 NA|NA|NA F Protein of unknown function DUF72 PGHMIELC_02960 220668.lp_0452 5.2e-71 273.5 Bacilli mutT 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1VKSD@1239,4HSQ6@91061,COG1051@1,COG1051@2 NA|NA|NA F DNA mismatch repair protein MutT PGHMIELC_02961 220668.lp_0454 0.0 1382.9 Lactobacillaceae metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 ko:K01874,ko:K01890,ko:K06878 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R03660,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPA1@1239,3F3XR@33958,4H9VC@91061,COG0073@1,COG0073@2,COG0143@1,COG0143@2 NA|NA|NA J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation PGHMIELC_02962 220668.lp_0455 9.2e-212 742.7 Lactobacillaceae bcr1 ko:K02030,ko:K07552 M00236 ko00000,ko00002,ko02000 2.A.1.2,3.A.1.3 Bacteria 1TR6I@1239,3F4Q9@33958,4HBX6@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_02963 220668.lp_0456 1.5e-146 525.4 Lactobacillaceae tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 ko:K03424 ko00000,ko01000 Bacteria 1TNY1@1239,3F3N2@33958,4HA74@91061,COG0084@1,COG0084@2 NA|NA|NA L hydrolase, TatD family PGHMIELC_02964 220668.lp_0457 2.6e-95 354.8 Lactobacillaceae rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985,ko:K07476 ko00000,ko01000 Bacteria 1V3K3@1239,3F64F@33958,4HH5Y@91061,COG1658@1,COG1658@2 NA|NA|NA J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step PGHMIELC_02965 220668.lp_0458 3.9e-159 567.4 Lactobacillaceae ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 R10716 RC00003,RC03257 ko00000,ko01000,ko03009 Bacteria 1TP9W@1239,3F3VC@33958,4HA4R@91061,COG0030@1,COG0030@2 NA|NA|NA J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits PGHMIELC_02966 220668.lp_0459 3.2e-37 160.6 Lactobacillaceae veg Bacteria 1VEQM@1239,3F7D3@33958,4HKF8@91061,COG4466@1,COG4466@2 NA|NA|NA S Biofilm formation stimulator VEG PGHMIELC_02967 220668.lp_0460 1.5e-163 582.0 Lactobacillaceae ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.1.1.182,2.7.1.148 ko:K00919,ko:K02528,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634,R10716 RC00002,RC00003,RC01439,RC03257 ko00000,ko00001,ko00002,ko01000,ko02000,ko03009 3.A.1.29 iEC55989_1330.EC55989_1304,iLJ478.TM1383,iYO844.BSU00460 Bacteria 1TPXV@1239,3F43W@33958,4HAV8@91061,COG1947@1,COG1947@2 NA|NA|NA F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol PGHMIELC_02968 220668.lp_0461 1.3e-181 642.1 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TQYU@1239,3F57F@33958,4HC4H@91061,COG1073@1,COG1073@2 NA|NA|NA S Prolyl oligopeptidase family PGHMIELC_02969 220668.lp_0463 9.8e-129 466.1 Lactobacillaceae fhuC 3.6.3.35 ko:K01990,ko:K02074,ko:K09817,ko:K19973 ko02010,map02010 M00242,M00244,M00254,M00792 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.15,3.A.1.15.15,3.A.1.15.3,3.A.1.15.5 Bacteria 1TQ68@1239,3F49M@33958,4HAZI@91061,COG1121@1,COG1121@2 NA|NA|NA P ABC transporter PGHMIELC_02970 220668.lp_0464 9.2e-131 473.0 Lactobacillaceae znuB ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 1V0SX@1239,3F4BC@33958,4HE09@91061,COG1108@1,COG1108@2 NA|NA|NA U ABC 3 transport family PGHMIELC_02971 220668.lp_0381 6.4e-43 180.6 Bacilli ankB ko:K06867 ko00000 Bacteria 1VBGD@1239,4HKQW@91061,COG0666@1,COG0666@2 NA|NA|NA S ankyrin repeats PGHMIELC_02972 220668.lp_0376 2.1e-31 141.4 Lactobacillaceae Bacteria 1U84J@1239,29QHX@1,30BHD@2,3FAIP@33958,4II20@91061 NA|NA|NA PGHMIELC_02973 220668.lp_0466 6.6e-148 530.0 Lactobacillaceae purR 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816,ko:K09685 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko03000,ko04147 Bacteria 1TPN9@1239,3F3NH@33958,4HB8I@91061,COG0503@1,COG0503@2 NA|NA|NA F pur operon repressor PGHMIELC_02974 220668.lp_0467 1.2e-207 729.2 Lactobacillaceae glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042,ko:K11528 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP88@1239,3F4I3@33958,4H9V5@91061,COG1207@1,COG1207@2 NA|NA|NA M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain PGHMIELC_02975 220668.lp_0469 1.8e-150 538.5 Lactobacillaceae bla1 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1UYZ3@1239,3F5IH@33958,4HFV8@91061,COG2367@1,COG2367@2 NA|NA|NA V Beta-lactamase enzyme family PGHMIELC_02976 220668.lp_0471 1.2e-177 629.0 Lactobacillaceae prs 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2848 Bacteria 1TQ6Q@1239,3F3U2@33958,4HB61@91061,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) PGHMIELC_02977 220668.lp_0472 2.4e-184 651.4 Lactobacillaceae Bacteria 1VA42@1239,3F5KP@33958,4HIW1@91061,COG1434@1,COG1434@2 NA|NA|NA S DUF218 domain PGHMIELC_02978 220668.lp_0473 2.2e-126 458.8 Lactobacillaceae Bacteria 1U5HU@1239,29NSH@1,309QI@2,3F5ZA@33958,4IF8M@91061 NA|NA|NA PGHMIELC_02979 220668.lp_0475 3.7e-148 530.8 Lactobacillaceae yxeH Bacteria 1TR16@1239,3F55S@33958,4HCZ6@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase PGHMIELC_02980 220668.lp_0476 9e-264 915.6 Lactobacillaceae ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 ko:K06885 ko00000 Bacteria 1TPVB@1239,3F442@33958,4HAX8@91061,COG1078@1,COG1078@2 NA|NA|NA S HD domain protein PGHMIELC_02981 220668.lp_0477 3.3e-155 554.3 Lactobacillaceae lipL GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.200,2.3.1.204 ko:K16869,ko:K18821 ko00000,ko01000 Bacteria 1TQKA@1239,3F575@33958,4HCPS@91061,COG0095@1,COG0095@2 NA|NA|NA H biotin lipoate A B protein ligase PGHMIELC_02982 220668.lp_0479 3.8e-78 297.4 Lactobacillaceae ywiB Bacteria 1V8IZ@1239,3F6AI@33958,4HIW0@91061,COG4506@1,COG4506@2 NA|NA|NA S Domain of unknown function (DUF1934) PGHMIELC_02983 1136177.KCA1_0413 4e-46 191.4 Lactobacillaceae rpoE GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Bacteria 1V6WX@1239,3F55D@33958,4HIUK@91061,COG3343@1,COG3343@2 NA|NA|NA K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling PGHMIELC_02984 220668.lp_0481 3.4e-310 1070.1 Lactobacillaceae pyrG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS01075,iNJ661.Rv1699 Bacteria 1TP34@1239,3F42X@33958,4H9X6@91061,COG0504@1,COG0504@2 NA|NA|NA F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates PGHMIELC_02985 220668.lp_0501 1.7e-243 848.2 Lactobacillaceae serS GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF987.Gmet_3528,iSDY_1059.SDY_2368 Bacteria 1TP4W@1239,3F3M6@33958,4H9Y4@91061,COG0172@1,COG0172@2 NA|NA|NA J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) PGHMIELC_02986 220668.lp_0502 6.8e-229 799.7 Lactobacillaceae tdcC GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015077,GO:0015078,GO:0015171,GO:0015175,GO:0015179,GO:0015194,GO:0015195,GO:0015238,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015711,GO:0015804,GO:0015807,GO:0015825,GO:0015826,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022889,GO:0022890,GO:0031224,GO:0031226,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1902475,GO:1902600,GO:1903825,GO:1905039 ko:K03837,ko:K03838 ko00000,ko02000 2.A.42.2.1,2.A.42.2.2 iAPECO1_1312.APECO1_3308,iE2348C_1286.E2348C_3406,iEC55989_1330.EC55989_3533,iECABU_c1320.ECABU_c35330,iECED1_1282.ECED1_3781,iECIAI1_1343.ECIAI1_3265,iECNA114_1301.ECNA114_4343,iECO103_1326.ECO103_3863,iECO26_1355.ECO26_4221,iECOK1_1307.ECOK1_3543,iECP_1309.ECP_3209,iECSE_1348.ECSE_3400,iECSF_1327.ECSF_2956,iECW_1372.ECW_m3385,iEKO11_1354.EKO11_0601,iLF82_1304.LF82_2232,iNRG857_1313.NRG857_15495,iSBO_1134.SBO_2981,iSbBS512_1146.SbBS512_E3241,iUMN146_1321.UM146_00750,iUTI89_1310.UTI89_C3551,iWFL_1372.ECW_m3385,ic_1306.c3874 Bacteria 1V00Q@1239,3F5WK@33958,4IF7J@91061,COG0814@1,COG0814@2 NA|NA|NA E amino acid PGHMIELC_02987 220668.lp_0505 3.7e-122 444.1 Lactobacillaceae sdaAB 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 1U8TZ@1239,3F4UB@33958,4HBD6@91061,COG1760@1,COG1760@2 NA|NA|NA E Serine dehydratase beta chain PGHMIELC_02988 220668.lp_0506 2.2e-157 561.6 Lactobacillaceae sdaAA 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 1TP79@1239,3F3X8@33958,4HAI1@91061,COG1760@1,COG1760@2 NA|NA|NA E L-serine dehydratase, iron-sulfur-dependent, alpha subunit PGHMIELC_02989 220668.lp_0507 6.4e-131 473.4 Lactobacillaceae Bacteria 1V2VD@1239,3F5VW@33958,4HHYZ@91061,COG2964@1,COG2964@2 NA|NA|NA S YheO-like PAS domain PGHMIELC_02990 220668.lp_0509 2.5e-26 124.0 Lactobacillaceae Bacteria 1U6VX@1239,2BW8P@1,30AMZ@2,3F8KF@33958,4IGPZ@91061 NA|NA|NA PGHMIELC_02991 220668.lp_0510 3.6e-238 830.5 Lactobacillaceae murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 iYO844.BSU37100 Bacteria 1TPAU@1239,3F3P8@33958,4H9KI@91061,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine PGHMIELC_02992 220668.lp_0511 3e-240 837.4 Lactobacillaceae rho ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Bacteria 1TPHZ@1239,3F43Y@33958,4H9XB@91061,COG1158@1,COG1158@2 NA|NA|NA K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template PGHMIELC_02993 1136177.KCA1_0423 7.8e-41 172.6 Lactobacillaceae rpmE2 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEGU@1239,3F7D7@33958,4HKF0@91061,COG0254@1,COG0254@2 NA|NA|NA J Ribosomal protein L31 PGHMIELC_02994 220668.lp_0513 9.4e-214 749.2 Lactobacillaceae Bacteria 1UHSE@1239,3F5YK@33958,4HEGH@91061,COG1503@1,COG1503@2 NA|NA|NA J translation release factor activity PGHMIELC_02995 220668.lp_0514 9.2e-127 459.5 Lactobacillaceae srtA 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 1V83Z@1239,3F54V@33958,4HJV9@91061,COG3764@1,COG3764@2 NA|NA|NA M sortase family PGHMIELC_02996 220668.lp_0515 1.7e-91 342.0 Lactobacillaceae lemA ko:K03744 ko00000 Bacteria 1V3Z0@1239,3F4TF@33958,4HH6H@91061,COG1704@1,COG1704@2 NA|NA|NA S LemA family PGHMIELC_02997 220668.lp_0516 1e-138 499.6 Lactobacillaceae htpX ko:K03799 M00743 ko00000,ko00002,ko01000,ko01002 Bacteria 1TP23@1239,3F40Z@33958,4HB11@91061,COG0501@1,COG0501@2 NA|NA|NA O Belongs to the peptidase M48B family PGHMIELC_02998 220668.lp_0517 2e-146 525.0 Lactobacillaceae Bacteria 1V46E@1239,29SV9@1,30E1E@2,3F6E2@33958,4HI7R@91061 NA|NA|NA PGHMIELC_02999 220668.lp_0518 1.2e-260 905.2 Lactobacillaceae murF 6.3.2.10,6.3.2.13 ko:K01928,ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R02788,R04573,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1VT78@1239,3F4SK@33958,4HACR@91061,COG0770@1,COG0770@2 NA|NA|NA M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein PGHMIELC_03000 220668.lp_0520 6.6e-258 896.3 Lactobacillaceae cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TPAP@1239,3F46Q@33958,4HAB3@91061,COG0513@1,COG0513@2 NA|NA|NA F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity PGHMIELC_03001 220668.lp_0522 1e-60 239.2 Lactobacillaceae acpS 2.7.6.3,2.7.8.7,5.1.1.1 ko:K00950,ko:K00997,ko:K01775 ko00473,ko00770,ko00790,ko01100,ko01502,map00473,map00770,map00790,map01100,map01502 M00126,M00841 R00401,R01625,R03503 RC00002,RC00017,RC00285 ko00000,ko00001,ko00002,ko01000,ko01011 iYO844.BSU04620 Bacteria 1VA0T@1239,3F6HC@33958,4HKBI@91061,COG0736@1,COG0736@2 NA|NA|NA I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein PGHMIELC_03002 220668.lp_0523 1.7e-215 755.0 Lactobacillaceae alr 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011 Bacteria 1TNYY@1239,3F3X2@33958,4HA95@91061,COG0787@1,COG0787@2 NA|NA|NA E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids PGHMIELC_03003 1136177.KCA1_0440 1.6e-64 251.9 Lactobacillaceae ndoA ko:K07171 ko00000,ko01000,ko02048 Bacteria 1V6DK@1239,3F6Y9@33958,4HGXF@91061,COG2337@1,COG2337@2 NA|NA|NA L Toxic component of a toxin-antitoxin (TA) module PGHMIELC_03004 220668.lp_0525 0.0 1264.2 Lactobacillaceae kup GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 ko:K03549 ko00000,ko02000 2.A.72 Bacteria 1TRUQ@1239,3F4CU@33958,4HA8Z@91061,COG3158@1,COG3158@2 NA|NA|NA P Transport of potassium into the cell PGHMIELC_03005 60520.HR47_08570 2.9e-193 681.0 Bacilli ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1UP5R@1239,4HIPS@91061,COG0715@1,COG0715@2 NA|NA|NA P ABC transporter, substratebinding protein PGHMIELC_03006 1136177.KCA1_0443 9.8e-130 469.9 Lactobacillaceae ssuC2 ko:K02050 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1TQ26@1239,3F4W8@33958,4HCJ7@91061,COG0600@1,COG0600@2 NA|NA|NA U Binding-protein-dependent transport system inner membrane component PGHMIELC_03007 60520.HR47_08560 5e-134 483.8 Lactobacillaceae ko:K02049,ko:K15555 ko00920,ko02010,map00920,map02010 M00188,M00436 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 Bacteria 1TRM6@1239,3FC3F@33958,4HBZ6@91061,COG1116@1,COG1116@2 NA|NA|NA P ATPases associated with a variety of cellular activities PGHMIELC_03008 220668.lp_0526 0.0 1961.8 Lactobacillaceae carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPID@1239,3F3MD@33958,4HAEY@91061,COG0458@1,COG0458@2 NA|NA|NA F Carbamoyl-phosphate synthase PGHMIELC_03009 220668.lp_0527 1.7e-204 718.4 Lactobacillaceae carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383,iYO844.BSU15510 Bacteria 1TQ8N@1239,3F43R@33958,4H9Z0@91061,COG0505@1,COG0505@2 NA|NA|NA F Carbamoyl-phosphate synthetase glutamine chain PGHMIELC_03010 220668.lp_0528 7.2e-189 666.4 Lactobacillaceae argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1782,iSSON_1240.SSON_4131,iYO844.BSU11190 Bacteria 1TPVI@1239,3F5DZ@33958,4H9YD@91061,COG0002@1,COG0002@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde PGHMIELC_03011 220668.lp_0529 2.6e-230 804.3 Lactobacillaceae argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 ko:K00620,ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1783 Bacteria 1TPBP@1239,3F433@33958,4H9TQ@91061,COG1364@1,COG1364@2 NA|NA|NA E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate PGHMIELC_03012 220668.lp_0530 9.4e-130 469.5 Lactobacillaceae argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP0N@1239,3F5QN@33958,4HH91@91061,COG0548@1,COG0548@2 NA|NA|NA F Belongs to the acetylglutamate kinase family. ArgB subfamily PGHMIELC_03013 220668.lp_0531 1.4e-217 761.9 Lactobacillaceae argD GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP9S@1239,3F52J@33958,4H9VZ@91061,COG4992@1,COG4992@2 NA|NA|NA E acetylornithine PGHMIELC_03014 220668.lp_0532 3.6e-188 664.1 Lactobacillaceae argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPF2@1239,3F48K@33958,4H9X8@91061,COG0078@1,COG0078@2 NA|NA|NA E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline PGHMIELC_03015 220668.lp_0533 1.2e-83 315.8 Lactobacillaceae Bacteria 1V463@1239,3FCEF@33958,4HH0P@91061,COG4708@1,COG4708@2 NA|NA|NA S QueT transporter PGHMIELC_03016 1291743.LOSG293_080270 3.1e-170 605.1 Lactobacillaceae oppA2 ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F4TA@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E Bacterial extracellular solute-binding proteins, family 5 Middle PGHMIELC_03017 1291743.LOSG293_080280 2.1e-123 448.7 Lactobacillaceae pepL 3.4.11.5 ko:K01259 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 1U46W@1239,3F5ZW@33958,4IDY6@91061,COG2267@1,COG2267@2 NA|NA|NA E Releases the N-terminal proline from various substrates PGHMIELC_03018 220668.lp_0535 2.1e-114 418.3 Lactobacillaceae Bacteria 1TR5G@1239,3F3JY@33958,4H9ZA@91061,COG0517@1,COG0517@2 NA|NA|NA S (CBS) domain PGHMIELC_03019 220668.lp_0536 1.4e-264 918.3 Lactobacillaceae Bacteria 1TQMA@1239,3F3QW@33958,4HDTN@91061,COG1376@1,COG1376@2 NA|NA|NA S Putative peptidoglycan binding domain PGHMIELC_03020 220668.lp_0537 3.5e-177 627.5 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPSY@1239,3F3RM@33958,4HB0Z@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily. LDH family PGHMIELC_03021 220668.lp_0538 1.5e-100 372.1 Lactobacillaceae pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 1V3NB@1239,3F3VZ@33958,4HH2Z@91061,COG0193@1,COG0193@2 NA|NA|NA J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis PGHMIELC_03022 220668.lp_0539 0.0 2269.2 Lactobacillaceae mfd ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPF1@1239,3F4KU@33958,4H9NB@91061,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site PGHMIELC_03023 220668.lp_0540 7.3e-289 999.2 Lactobacillaceae yabM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03328,ko:K06409 ko00000,ko02000 2.A.66.2,2.A.66.2.14 Bacteria 1TNYX@1239,3F4BV@33958,4HACG@91061,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein PGHMIELC_03024 220668.lp_0541 2.2e-42 177.9 Lactobacillaceae yabO GO:0008150,GO:0040007 Bacteria 1VEI5@1239,3F7JX@33958,4HKJJ@91061,COG1188@1,COG1188@2 NA|NA|NA J S4 domain protein PGHMIELC_03026 220668.lp_0542 1.1e-63 249.2 Lactobacillaceae divIC ko:K05589,ko:K13052 ko00000,ko03036 Bacteria 1VKC5@1239,3F76Z@33958,4HR53@91061,COG2919@1,COG2919@2 NA|NA|NA D Septum formation initiator PGHMIELC_03027 220668.lp_0543 3.1e-74 284.6 Lactobacillaceae yabR ko:K07570,ko:K07571 ko00000 Bacteria 1V6FE@1239,3F6HV@33958,4HIKM@91061,COG1098@1,COG1098@2 NA|NA|NA J RNA binding PGHMIELC_03028 220668.lp_0545 1.1e-253 882.1 Lactobacillaceae tilS 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 1TPXP@1239,3F4GY@33958,4H9ZM@91061,COG0037@1,COG0037@2 NA|NA|NA J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine PGHMIELC_03029 220668.lp_0546 1.7e-96 358.6 Lactobacillaceae hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 Bacteria 1V1C9@1239,3F56C@33958,4HFZ2@91061,COG0634@1,COG0634@2 NA|NA|NA F Belongs to the purine pyrimidine phosphoribosyltransferase family PGHMIELC_03030 220668.lp_0547 0.0 1280.8 Lactobacillaceae ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 ko:K03798 M00742 ko00000,ko00002,ko01000,ko01002,ko03110 Bacteria 1TPTV@1239,3F49Z@33958,4HAJB@91061,COG0465@1,COG0465@2 NA|NA|NA O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins PGHMIELC_03031 220668.lp_0548 1.2e-163 582.4 Lactobacillaceae hslO GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008 ko:K04083 ko00000,ko03110 Bacteria 1TRCH@1239,3F42B@33958,4HAFR@91061,COG1281@1,COG1281@2 NA|NA|NA O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress PGHMIELC_03032 220668.lp_0549 1.1e-189 669.1 Lactobacillaceae dus ko:K05540 ko00000,ko01000,ko03016 Bacteria 1TQ2R@1239,3F4C6@33958,4HA9K@91061,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines PGHMIELC_03033 220668.lp_0550 3e-292 1010.4 Lactobacillaceae lysS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP2P@1239,3F439@33958,4H9X4@91061,COG1190@1,COG1190@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family PGHMIELC_03036 220668.lp_0551 3e-252 877.5 Lactobacillaceae dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03305 ko00000 2.A.17 Bacteria 1TP81@1239,3F4WU@33958,4HAF2@91061,COG3104@1,COG3104@2 NA|NA|NA U amino acid peptide transporter PGHMIELC_03037 220668.lp_0552 2e-151 541.6 Lactobacillaceae yjjH Bacteria 1VHY9@1239,3F3SW@33958,4HPAR@91061,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase PGHMIELC_03041 220668.lp_0555 1.2e-49 202.2 Lactobacillaceae 5.3.3.19 ko:K19547 ko01130,map01130 M00787 ko00000,ko00001,ko00002,ko01000 Bacteria 1TTZM@1239,3F77A@33958,4IFX2@91061,COG1917@1,COG1917@2 NA|NA|NA S Cupin 2, conserved barrel domain protein PGHMIELC_03042 220668.lp_0556 3.2e-53 214.2 Lactobacillaceae Bacteria 1V6IB@1239,3F6JU@33958,4HNBA@91061,COG1917@1,COG1917@2 NA|NA|NA S Cupin domain PGHMIELC_03043 220668.lp_0557 1.1e-166 592.4 Lactobacillaceae pphA 3.1.3.16 ko:K01090,ko:K07313 ko00000,ko01000 Bacteria 1V1HN@1239,3F401@33958,4HF40@91061,COG0639@1,COG0639@2 NA|NA|NA T Calcineurin-like phosphoesterase PGHMIELC_03044 220668.lp_0558 7.5e-192 676.4 Lactobacillaceae ybiR GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1TQCH@1239,3F4CJ@33958,4HEW7@91061,COG1055@1,COG1055@2 NA|NA|NA P Citrate transporter PGHMIELC_03045 220668.lp_0559 2.4e-150 538.1 Lactobacillaceae pnuC ko:K03811 ko00000,ko02000 4.B.1.1 Bacteria 1UYDN@1239,3F469@33958,4HJE5@91061,COG3201@1,COG3201@2 NA|NA|NA H nicotinamide mononucleotide transporter PGHMIELC_03046 220668.lp_0561 1.7e-137 495.4 Lactobacillaceae proC 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1E@1239,3FB7S@33958,4HCBY@91061,COG0345@1,COG0345@2 NA|NA|NA E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline PGHMIELC_03047 220668.lp_0562 6.1e-221 773.1 Lactobacillaceae nagA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046348,GO:0046872,GO:0046914,GO:0046983,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 R02059 RC00166,RC00300 ko00000,ko00001,ko01000 Bacteria 1TPFK@1239,3F40F@33958,4HC6C@91061,COG1820@1,COG1820@2 NA|NA|NA G Belongs to the metallo-dependent hydrolases superfamily. NagA family PGHMIELC_03048 220668.lp_0563 1.6e-123 448.7 Lactobacillaceae gntR1 ko:K03710,ko:K11922 ko00000,ko03000 Bacteria 1UYBW@1239,3F4D0@33958,4HDDG@91061,COG2188@1,COG2188@2 NA|NA|NA K UbiC transcription regulator-associated domain protein PGHMIELC_03049 220668.lp_0564 1.3e-136 492.3 Lactobacillaceae tagA 2.4.1.187 ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 GT26 Bacteria 1V3QV@1239,3F4WB@33958,4HH6B@91061,COG1922@1,COG1922@2 NA|NA|NA F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid PGHMIELC_03050 220668.lp_0565 5.2e-289 999.6 Lactobacillaceae pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 iYO844.BSU31750 Bacteria 1TPDW@1239,3F3K7@33958,4HAI4@91061,COG1488@1,COG1488@2 NA|NA|NA F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP PGHMIELC_03051 220668.lp_0566 4.7e-154 550.4 Lactobacillaceae nadE GO:0003674,GO:0003824,GO:0003952,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0033554,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_1910,iECW_1372.ECW_m1909,iEKO11_1354.EKO11_2035,iETEC_1333.ETEC_1772,iEcE24377_1341.EcE24377A_1961,iSFV_1184.SFV_1480,iSF_1195.SF1486,iSFxv_1172.SFxv_1676,iSSON_1240.SSON_1418,iS_1188.S1603,iWFL_1372.ECW_m1909 Bacteria 1TQ38@1239,3F43Z@33958,4HA2R@91061,COG0171@1,COG0171@2 NA|NA|NA F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source PGHMIELC_03052 220668.lp_0567 0.0 1597.4 Lactobacillaceae pacL 3.6.3.8 ko:K01537 ko00000,ko01000 3.A.3.2 Bacteria 1TPF5@1239,3F3KP@33958,4H9S5@91061,COG0474@1,COG0474@2 NA|NA|NA P P-type ATPase PGHMIELC_03053 220668.lp_0568 8.9e-72 276.2 Lactobacillaceae ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1VFU9@1239,2E7AN@1,331U3@2,3F69A@33958,4HP1H@91061 NA|NA|NA PGHMIELC_03054 220668.lp_0569 0.0 1409.4 Lactobacillaceae yhgF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 ko:K06959 ko00000 Bacteria 1TPFE@1239,3F415@33958,4HAGY@91061,COG2183@1,COG2183@2 NA|NA|NA K Tex-like protein N-terminal domain protein PGHMIELC_03055 220668.lp_0570 1.8e-80 305.1 Lactobacillaceae ydcK ko:K03095 ko00000 Bacteria 1V6NU@1239,3F703@33958,4HIHY@91061,COG3091@1,COG3091@2 NA|NA|NA S Belongs to the SprT family PGHMIELC_03056 220668.lp_0571 4e-237 827.0 Lactobacillaceae hom GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1294,iSB619.SA_RS06610 Bacteria 1TQ2H@1239,3F5BM@33958,4HBAP@91061,COG0460@1,COG0460@2 NA|NA|NA E homoserine dehydrogenase PGHMIELC_03057 220668.lp_0572 1.4e-156 558.9 Lactobacillaceae thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545,iSB619.SA_RS06620 Bacteria 1TRWS@1239,3F44T@33958,4HCQN@91061,COG0083@1,COG0083@2 NA|NA|NA F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate PGHMIELC_03059 1499680.CCFE01000010_gene99 4.9e-09 67.0 Bacillus 2.1.1.72,3.1.21.3 ko:K01154,ko:K03933,ko:K07316 ko00000,ko01000,ko02048 AA10,CBM73 Bacteria 1UK7A@1239,1ZM7B@1386,4IMY6@91061,COG2189@1,COG2189@2 NA|NA|NA L Belongs to the N(4) N(6)-methyltransferase family PGHMIELC_03060 1136177.KCA1_2329 4.2e-20 104.8 Lactobacillaceae Bacteria 1U8FV@1239,29QQ9@1,30BQ0@2,3FAXV@33958,4IIDQ@91061 NA|NA|NA PGHMIELC_03061 60520.HR47_01955 0.0 1136.3 Lactobacillaceae ybfG Bacteria 1TPV1@1239,3F5J4@33958,4HCRA@91061,COG3409@1,COG3409@2 NA|NA|NA M peptidoglycan-binding domain-containing protein PGHMIELC_03064 220668.lp_0574 2.4e-160 571.6 Lactobacillaceae Bacteria 1V7GB@1239,3F5VT@33958,4I28M@91061,COG4990@1,COG4990@2 NA|NA|NA G Peptidase_C39 like family PGHMIELC_03065 1136177.KCA1_0493 1.3e-168 599.0 Lactobacillaceae manL 2.7.1.191 ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1TQJ4@1239,3F4PU@33958,4H9Z8@91061,COG2893@1,COG2893@2,COG3444@1,COG3444@2 NA|NA|NA G PTS system sorbose subfamily IIB component PGHMIELC_03066 1136177.KCA1_0494 3.4e-133 481.1 Lactobacillaceae manY ko:K02795,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1TPKK@1239,3F3V5@33958,4H9QI@91061,COG3715@1,COG3715@2 NA|NA|NA G PTS system PGHMIELC_03067 1136177.KCA1_0495 3.6e-171 607.4 Lactobacillaceae manN ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1TQA3@1239,3F3KR@33958,4HA3K@91061,COG3716@1,COG3716@2 NA|NA|NA G system, mannose fructose sorbose family IID component PGHMIELC_03068 1136177.KCA1_0496 4.7e-64 250.4 Lactobacillaceae Bacteria 1V6KV@1239,3F719@33958,4HIMF@91061,COG4687@1,COG4687@2 NA|NA|NA S Domain of unknown function (DUF956) PGHMIELC_03069 220668.lp_0585 0.0 1840.1 Lactobacillaceae levR Bacteria 1VSHE@1239,3F3N6@33958,4HB6T@91061,COG1221@1,COG1221@2,COG3933@1,COG3933@2 NA|NA|NA K Sigma-54 interaction domain PGHMIELC_03070 220668.lp_0586 8.6e-72 276.2 Lactobacillaceae pts10A 2.7.1.191 ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1VB2D@1239,3F68F@33958,4HMGK@91061,COG2893@1,COG2893@2 NA|NA|NA G PTS system fructose IIA component PGHMIELC_03071 220668.lp_0587 3.1e-87 327.8 Lactobacillaceae pts10B 2.7.1.191,2.7.1.202 ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 M00273,M00276 R02630,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.6.1 Bacteria 1V3X7@1239,3FC7Q@33958,4HH17@91061,COG3444@1,COG3444@2 NA|NA|NA G PTS system sorbose subfamily IIB component PGHMIELC_03072 220668.lp_0588 4.6e-177 627.1 Lactobacillaceae fabH 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TP0K@1239,3F3XP@33958,4HATK@91061,COG0332@1,COG0332@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids PGHMIELC_03073 220668.lp_0589 9.7e-65 252.7 Lactobacillaceae accB 2.3.1.12 ko:K00627,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1W5SI@1239,3F6T1@33958,4I105@91061,COG0511@1,COG0511@2 NA|NA|NA I Biotin-requiring enzyme PGHMIELC_03074 220668.lp_0590 7.5e-247 859.4 Lactobacillaceae accC2 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1VTG5@1239,3F5P4@33958,4HTGT@91061,COG0439@1,COG0439@2 NA|NA|NA I Biotin carboxylase C-terminal domain PGHMIELC_03075 220668.lp_0591 9.8e-141 506.1 Lactobacillaceae accD 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4U@1239,3F6E6@33958,4HUXJ@91061,COG0777@1,COG0777@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA PGHMIELC_03076 220668.lp_0592 1.8e-136 491.9 Lactobacillaceae accA 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1VUKP@1239,3F6JV@33958,4HVWX@91061,COG0825@1,COG0825@2 NA|NA|NA I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit PGHMIELC_03077 220668.lp_0593 4.9e-168 597.4 Lactobacillaceae brpA Bacteria 1TR1B@1239,3F3MQ@33958,4HA09@91061,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-like function transcriptional attenuator common domain protein PGHMIELC_03078 220668.lp_0594 3.3e-167 594.3 Lactobacillaceae mleP2 ko:K07088 ko00000 Bacteria 1UY4N@1239,3FCFH@33958,4HB48@91061,COG0679@1,COG0679@2 NA|NA|NA S Transporter, auxin efflux carrier (AEC) family protein PGHMIELC_03079 220668.lp_0595 1.7e-177 628.6 Lactobacillaceae Bacteria 1UHT1@1239,3F4PS@33958,4HCWY@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family PGHMIELC_03080 220668.lp_0597 2.5e-129 468.0 Lactobacillaceae gpmA GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1V2UT@1239,3F443@33958,4HGRK@91061,COG0588@1,COG0588@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate PGHMIELC_03081 220668.lp_0600 1.1e-112 412.5 Lactobacillaceae zmp2 Bacteria 1U5B3@1239,3F5EV@33958,4IF2F@91061,COG5549@1,COG5549@2 NA|NA|NA O Zinc-dependent metalloprotease PGHMIELC_03082 220668.lp_0601 7.3e-258 896.0 Lactobacillaceae pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 1TRJN@1239,3F49B@33958,4HBZ9@91061,COG3579@1,COG3579@2 NA|NA|NA E Peptidase C1-like family PGHMIELC_03083 220668.lp_0602 3.2e-124 451.1 Lactobacillaceae rpiA GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,5.3.1.6 ko:K00851,ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056,R01737 RC00002,RC00017,RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria 1V1DB@1239,3F43N@33958,4HFQ7@91061,COG0120@1,COG0120@2 NA|NA|NA G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate PGHMIELC_03084 220668.lp_0603 1.2e-51 208.8 Lactobacillaceae HA62_12640 ko:K06975 ko00000 Bacteria 1VEEX@1239,3F80F@33958,4HNR2@91061,COG2388@1,COG2388@2 NA|NA|NA S GCN5-related N-acetyl-transferase PGHMIELC_03085 220668.lp_0604 2.1e-99 368.2 Lactobacillaceae dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 ko:K01520,ko:K13038 ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100 M00053,M00120 R02100,R03269,R04231,R11896 RC00002,RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1V6HX@1239,3F65D@33958,4HIZ3@91061,COG0756@1,COG0756@2 NA|NA|NA F dUTP diphosphatase PGHMIELC_03086 220668.lp_0606 1.3e-257 895.2 Lactobacillaceae radA ko:K04485 ko00000,ko03400 Bacteria 1TQ7Y@1239,3F3W8@33958,4H9YC@91061,COG1066@1,COG1066@2 NA|NA|NA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function PGHMIELC_03087 220668.lp_0607 3.7e-205 720.7 Lactobacillaceae yacL GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 Bacteria 1TP0P@1239,3F46T@33958,4H9NQ@91061,COG4956@1,COG4956@2 NA|NA|NA S domain protein PGHMIELC_03088 220668.lp_0609 8.9e-289 998.8 Lactobacillaceae gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009986,GO:0030246,GO:0030247,GO:0044424,GO:0044464,GO:2001065 6.1.1.17,6.1.1.24 ko:K01885,ko:K09698 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 iSB619.SA_RS02860 Bacteria 1TPJC@1239,3F3PR@33958,4HAKH@91061,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) PGHMIELC_03089 220668.lp_0610 2e-269 934.5 Lactobacillaceae cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16,6.3.1.13 ko:K01883,ko:K15526 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECUMN_1333.ECUMN_0566,iJN746.PP_2905 Bacteria 1TP9D@1239,3F4K7@33958,4HA6D@91061,COG0215@1,COG0215@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family PGHMIELC_03090 220668.lp_0611 3.5e-70 270.8 Lactobacillaceae mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 ko:K11145 ko00000,ko01000,ko03009 Bacteria 1VA5V@1239,3F6HS@33958,4HIM3@91061,COG1939@1,COG1939@2 NA|NA|NA J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) PGHMIELC_03091 220668.lp_0612 3.3e-138 497.7 Lactobacillaceae rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218,ko:K03437,ko:K12952 ko00000,ko01000,ko03009,ko03016 3.A.3.23 Bacteria 1TP9G@1239,3F3TD@33958,4HBBI@91061,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family PGHMIELC_03092 220668.lp_0613 5.3e-98 363.6 Lactobacillaceae yacP ko:K06962 ko00000 Bacteria 1V9XR@1239,3F5KC@33958,4HFW4@91061,COG3688@1,COG3688@2 NA|NA|NA S YacP-like NYN domain PGHMIELC_03093 220668.lp_0614 1.2e-100 372.5 Lactobacillaceae sigH ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Bacteria 1TP55@1239,3FBRS@33958,4HAHR@91061,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70 region 2 PGHMIELC_03094 1136177.KCA1_0523 6.5e-22 109.0 Lactobacillaceae rpmG ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VFTQ@1239,3F83F@33958,4HR5Q@91061,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family PGHMIELC_03095 220668.lp_0616 6.8e-29 132.5 Lactobacillaceae secE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VK48@1239,3F86Y@33958,4HR1W@91061,COG0690@1,COG0690@2 NA|NA|NA U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation PGHMIELC_03096 220668.lp_0617 1.4e-98 365.5 Lactobacillaceae nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 1TR3P@1239,3F55W@33958,4HAJA@91061,COG0250@1,COG0250@2 NA|NA|NA K Participates in transcription elongation, termination and antitermination PGHMIELC_03097 60520.HR47_02280 1.1e-158 565.8 Lactobacillaceae Bacteria 1V910@1239,3F4RX@33958,4HF90@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF915) PGHMIELC_03098 220668.lp_0619 2.4e-69 268.1 Lactobacillaceae rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1BS@1239,3F64I@33958,4HFQ0@91061,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors PGHMIELC_03099 220668.lp_0620 5.1e-122 443.7 Lactobacillaceae rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPTS@1239,3F3VQ@33958,4HAK4@91061,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release PGHMIELC_03100 220668.lp_0621 4.6e-80 303.9 Lactobacillaceae rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3JJ@1239,3F4S4@33958,4HH0N@91061,COG0244@1,COG0244@2 NA|NA|NA J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors PGHMIELC_03101 1136177.KCA1_0530 9.9e-56 222.6 Lactobacillaceae rplL ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6EI@1239,3F6YA@33958,4HIGQ@91061,COG0222@1,COG0222@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation PGHMIELC_03103 220668.lp_0624 1.2e-230 805.4 Lactobacillaceae Bacteria 1VJ2V@1239,3F4UK@33958,4HPCG@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family PGHMIELC_03106 1158604.I591_00757 8.9e-33 147.1 Enterococcaceae Bacteria 1VHR9@1239,2EF86@1,33916@2,4B4JF@81852,4HQR5@91061 NA|NA|NA PGHMIELC_03109 1423806.JCM15457_247 1.6e-09 69.7 Lactobacillaceae Bacteria 1VP04@1239,3F84E@33958,4HRP9@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain PGHMIELC_03111 1158604.I591_00761 2.7e-12 78.6 Enterococcaceae Bacteria 1VGZ4@1239,4B2RM@81852,4IRTZ@91061,COG2856@1,COG2856@2 NA|NA|NA E IrrE N-terminal-like domain PGHMIELC_03112 52979.O03970_9CAUD 1.3e-40 172.6 dsDNA viruses, no RNA stage Viruses 4QUPK@35237 NA|NA|NA S protein disulfide oxidoreductase activity PGHMIELC_03113 862514.HMPREF0623_0261 5.6e-13 80.1 Lactobacillaceae Bacteria 1W4KH@1239,2DFEZ@1,2ZRKX@2,3FBQV@33958,4I1P1@91061 NA|NA|NA PGHMIELC_03119 220668.lp_0637 3.5e-97 360.9 Lactobacillaceae Bacteria 1U6II@1239,2C8QA@1,30ADW@2,3F7ZD@33958,4IGAW@91061 NA|NA|NA PGHMIELC_03122 525318.HMPREF0497_2327 2.9e-26 124.4 Bacilli Bacteria 1VJSN@1239,2EI6M@1,33BXY@2,4HRY0@91061 NA|NA|NA PGHMIELC_03123 220668.lp_2443 1.1e-09 68.2 Bacilli ko:K09946 ko00000 Bacteria 1U493@1239,4HZH1@91061,COG3422@1,COG3422@2 NA|NA|NA S Domain of unknown function (DUF1508) PGHMIELC_03124 60520.HR47_13610 2.6e-32 145.2 Lactobacillaceae Bacteria 1U7J5@1239,29Q5Y@1,30B4U@2,3F9SU@33958,4IHFZ@91061 NA|NA|NA PGHMIELC_03125 60520.HR47_13600 7.6e-139 500.0 Lactobacillaceae pi112 3.6.4.12 ko:K03657,ko:K16898 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1UQ@1239,3F51S@33958,4HGSG@91061,COG1074@1,COG1074@2 NA|NA|NA L PDDEXK-like domain of unknown function (DUF3799) PGHMIELC_03126 220668.lp_2437 2.8e-11 73.2 Lactobacillaceae 3.1.3.16 ko:K01090 ko00000,ko01000 Bacteria 1U6IF@1239,3F7Z7@33958,4IGAS@91061,COG3935@1,COG3935@2 NA|NA|NA L DnaD domain protein PGHMIELC_03127 1158614.I592_03442 8.6e-42 177.2 Enterococcaceae Bacteria 1UY67@1239,4B2FZ@81852,4HEBJ@91061,COG4823@1,COG4823@2 NA|NA|NA V Abi-like protein PGHMIELC_03128 220668.lp_0688 2.7e-177 627.9 Lactobacillaceae ko:K15051 ko00000 Bacteria 1TR37@1239,3F4MB@33958,4HHHQ@91061,COG2169@1,COG2169@2 NA|NA|NA F DNA/RNA non-specific endonuclease PGHMIELC_03129 220668.lp_0689 1.5e-38 166.4 Lactobacillaceae ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1V8AM@1239,3F813@33958,4IPMQ@91061,COG1525@1,COG1525@2 NA|NA|NA L nuclease PGHMIELC_03130 220668.lp_0690 0.0 1681.4 Lactobacillaceae mprF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 ko:K07027,ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 2.A.1.3.37,4.D.2 iYO844.BG12900 Bacteria 1TQI2@1239,3F3PY@33958,4HBHU@91061,COG0392@1,COG0392@2,COG2898@1,COG2898@2 NA|NA|NA S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms PGHMIELC_03131 220668.lp_0691 4.6e-108 397.1 Lactobacillaceae yvdD GO:0003674,GO:0003824,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009690,GO:0009691,GO:0009987,GO:0010817,GO:0016787,GO:0016798,GO:0016799,GO:0034754,GO:0042445,GO:0042446,GO:0044237,GO:0044249,GO:0046483,GO:0065007,GO:0065008,GO:0071704,GO:1901564 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 1UKED@1239,3F5U4@33958,4HE2X@91061,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family PGHMIELC_03132 220668.lp_0692 2.2e-198 698.0 Lactobacillaceae nrdF 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1TQTH@1239,3F3P1@33958,4H9WX@91061,COG0208@1,COG0208@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides PGHMIELC_03133 220668.lp_0693 0.0 1456.0 Lactobacillaceae nrdE 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 iYO844.BSU17380 Bacteria 1TPFH@1239,3F3XG@33958,4H9X0@91061,COG0209@1,COG0209@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides PGHMIELC_03134 220668.lp_0694 6.5e-37 159.5 Lactobacillaceae nrdH GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009893,GO:0009987,GO:0016491,GO:0019222,GO:0019725,GO:0022900,GO:0042592,GO:0043085,GO:0044093,GO:0044237,GO:0045454,GO:0048518,GO:0050789,GO:0050790,GO:0050794,GO:0051341,GO:0051353,GO:0055114,GO:0065007,GO:0065008,GO:0065009 ko:K06191 ko00000 Bacteria 1VEFX@1239,3F874@33958,4HNUX@91061,COG0695@1,COG0695@2 NA|NA|NA O Glutaredoxin PGHMIELC_03135 220668.lp_0695 3.4e-109 401.0 Lactobacillaceae rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1V1BG@1239,3F4NU@33958,4HHCA@91061,COG2813@1,COG2813@2 NA|NA|NA J Methyltransferase PGHMIELC_03136 220668.lp_0696 5.9e-91 340.1 Lactobacillaceae tadA 3.5.4.33 ko:K11991 R10223 RC00477 ko00000,ko01000,ko03016 Bacteria 1V3HZ@1239,3F6IS@33958,4HH7S@91061,COG0590@1,COG0590@2 NA|NA|NA F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) PGHMIELC_03137 220668.lp_0698 0.0 1100.5 Lactobacillaceae dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02341,ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPS9@1239,3F3P2@33958,4HAUE@91061,COG2812@1,COG2812@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity PGHMIELC_03138 220668.lp_0699 5.8e-41 173.3 Lactobacillaceae yaaK ko:K09747 ko00000 Bacteria 1VA1S@1239,3F7F3@33958,4HKH3@91061,COG0718@1,COG0718@2 NA|NA|NA S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection PGHMIELC_03139 1136177.KCA1_0545 7.4e-109 399.8 Lactobacillaceae recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1TR87@1239,3F4JQ@33958,4HAZR@91061,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO PGHMIELC_03140 220668.lp_0701 2.2e-38 164.5 Lactobacillaceae yaaL Bacteria 1VM3Z@1239,2EHEM@1,33B6J@2,3F844@33958,4HR3I@91061 NA|NA|NA S Protein of unknown function (DUF2508) PGHMIELC_03141 220668.lp_0703 8.7e-119 433.0 Lactobacillaceae tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS02535 Bacteria 1V1HE@1239,3F4JR@33958,4HGWR@91061,COG0125@1,COG0125@2 NA|NA|NA F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis PGHMIELC_03142 220668.lp_0704 2.4e-53 214.5 Lactobacillaceae yaaQ Bacteria 1V6NI@1239,3F6VW@33958,4HIHA@91061,COG3870@1,COG3870@2 NA|NA|NA S Cyclic-di-AMP receptor PGHMIELC_03143 220668.lp_0705 9.7e-186 656.0 Lactobacillaceae holB 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TRVS@1239,3F50D@33958,4HA3T@91061,COG0470@1,COG0470@2 NA|NA|NA L DNA polymerase III PGHMIELC_03144 220668.lp_0706 1e-57 229.2 Lactobacillaceae yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 Bacteria 1VA1F@1239,3F864@33958,4HKND@91061,COG4467@1,COG4467@2 NA|NA|NA L Involved in initiation control of chromosome replication PGHMIELC_03145 220668.lp_0707 5.4e-164 583.6 Lactobacillaceae rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 1TP6U@1239,3F4AI@33958,4HAH8@91061,COG0313@1,COG0313@2 NA|NA|NA H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA PGHMIELC_03146 220668.lp_0708 2.1e-148 531.6 Lactobacillaceae fat 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 Bacteria 1V3RB@1239,3F41B@33958,4HHJ4@91061,COG3884@1,COG3884@2 NA|NA|NA I Acyl-ACP thioesterase PGHMIELC_03147 220668.lp_0709 2e-191 674.9 Lactobacillaceae galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ7N@1239,3F3YF@33958,4H9U5@91061,COG1087@1,COG1087@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family PGHMIELC_03148 220668.lp_0710 6.1e-210 736.5 Lactobacillaceae phnW GO:0003674,GO:0003824 2.5.1.49,2.6.1.37,3.11.1.1 ko:K01740,ko:K03430,ko:K05306 ko00270,ko00440,ko01100,ko01120,map00270,map00440,map01100,map01120 R00747,R01287,R04152,R04859 RC00008,RC00020,RC00062,RC00368,RC02821,RC02848 ko00000,ko00001,ko01000,ko01007 Bacteria 1TPS0@1239,3F43T@33958,4HBFN@91061,COG0075@1,COG0075@2 NA|NA|NA E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily PGHMIELC_03149 220668.lp_0711 6.5e-145 520.0 Lactobacillaceae phnX GO:0003674,GO:0003824 2.6.1.37,3.1.3.18,3.11.1.1 ko:K01091,ko:K03430,ko:K05306 ko00440,ko00630,ko01100,ko01110,ko01120,ko01130,map00440,map00630,map01100,map01110,map01120,map01130 R00747,R01334,R04152 RC00008,RC00017,RC00062,RC00368 ko00000,ko00001,ko01000,ko01007 Bacteria 1TP1A@1239,3F5WZ@33958,4HC8X@91061,COG0637@1,COG0637@2 NA|NA|NA E Belongs to the HAD-like hydrolase superfamily. PhnX family PGHMIELC_03150 220668.lp_0712 2.6e-144 518.1 Lactobacillaceae phnE1 3.6.1.63 ko:K02042,ko:K06162 ko00440,ko02010,map00440,map02010 M00223 R10186 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 Bacteria 1TQ73@1239,3FB6V@33958,4HD3S@91061,COG3639@1,COG3639@2 NA|NA|NA U ABC transporter permease PGHMIELC_03151 60520.HR47_07220 2.3e-137 495.0 Lactobacillaceae phnE 3.6.1.63 ko:K02042,ko:K06162 ko00440,ko02010,map00440,map02010 M00223 R10186 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 Bacteria 1TR1S@1239,3FB6W@33958,4HDQQ@91061,COG3639@1,COG3639@2 NA|NA|NA U Phosphonate ABC transporter permease PGHMIELC_03152 220668.lp_0714 9.7e-138 496.1 Lactobacillaceae phnC 3.6.3.28 ko:K02041 ko02010,map02010 M00223 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 Bacteria 1TQG6@1239,3F3SJ@33958,4HC3N@91061,COG3638@1,COG3638@2 NA|NA|NA P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system PGHMIELC_03153 220668.lp_0715 1.9e-189 668.3 Lactobacillaceae phnD ko:K02044 ko02010,map02010 M00223 ko00000,ko00001,ko00002,ko02000 3.A.1.9 Bacteria 1TR0H@1239,3F3KK@33958,4HBJQ@91061,COG3221@1,COG3221@2 NA|NA|NA P Phosphonate ABC transporter PGHMIELC_03154 220668.lp_0717 1.7e-128 465.3 Lactobacillaceae yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03016 Bacteria 1V4YX@1239,3F3WV@33958,4HHD7@91061,COG1214@1,COG1214@2 NA|NA|NA O Universal bacterial protein YeaZ PGHMIELC_03155 220668.lp_0718 6.7e-101 373.2 Lactobacillaceae rimI 2.3.1.128 ko:K03789 ko00000,ko01000,ko03009 Bacteria 1V6KU@1239,3F522@33958,4HIKU@91061,COG0454@1,COG0456@2 NA|NA|NA K Ribosomal-protein-alanine acetyltransferase PGHMIELC_03156 220668.lp_0720 3.8e-81 307.4 Lactobacillaceae rimI 2.3.1.128 ko:K03789 ko00000,ko01000,ko03009 Bacteria 1V6KU@1239,3F6PY@33958,4HP50@91061,COG0454@1,COG0456@2 NA|NA|NA K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 PGHMIELC_03157 220668.lp_0721 1.4e-195 688.7 Lactobacillaceae tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1TQDR@1239,3F4AX@33958,4HANB@91061,COG0533@1,COG0533@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction PGHMIELC_03158 220668.lp_0723 5.7e-307 1059.7 Lactobacillaceae uup ko:K06158 ko00000,ko03012 Bacteria 1TPAX@1239,3F3QI@33958,4HBVV@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein PGHMIELC_03159 220668.lp_0725 1.4e-119 435.6 Lactobacillaceae rex ko:K01926 ko00000,ko03000 Bacteria 1TSMR@1239,3F40G@33958,4HB7Q@91061,COG2344@1,COG2344@2 NA|NA|NA K Modulates transcription in response to changes in cellular NADH NAD( ) redox state PGHMIELC_03160 220668.lp_0726 4.6e-109 400.6 Lactobacillaceae ydiL ko:K07052 ko00000 Bacteria 1UZGJ@1239,3F5JU@33958,4HFCB@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity PGHMIELC_03161 220668.lp_0727 1e-31 142.5 Lactobacillaceae groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0032991,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:0101031,GO:1903506,GO:1990220,GO:2000112,GO:2001141 ko:K04078 ko00000,ko03029,ko03110 Bacteria 1V9ZM@1239,3F7CZ@33958,4HKEK@91061,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter PGHMIELC_03162 220668.lp_0728 8.5e-293 1012.3 Lactobacillaceae groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 1TP1T@1239,3F3MM@33958,4HA38@91061,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions PGHMIELC_03163 220668.lp_0729 0.0 1150.6 Lactobacillaceae ydaO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 Bacteria 1TQE1@1239,3F44Y@33958,4HAZH@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid PGHMIELC_03164 220668.lp_0730 2.7e-181 641.3 Lactobacillaceae tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 ko:K02851 R08856 RC00002 ko00000,ko01000,ko01003,ko01005 Bacteria 1TP9V@1239,3F4JV@33958,4H9KT@91061,COG0472@1,COG0472@2 NA|NA|NA M transferase PGHMIELC_03165 220668.lp_0733 4.3e-145 520.8 Lactobacillaceae pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TQ5X@1239,3F4ER@33958,4HBEB@91061,COG0226@1,COG0226@2 NA|NA|NA P Phosphate PGHMIELC_03166 220668.lp_0734 5.7e-115 420.2 Lactobacillaceae yvyE 3.4.13.9 ko:K01271 ko00000,ko01000,ko01002 Bacteria 1V6MQ@1239,3F3SQ@33958,4HBIT@91061,COG1739@1,COG1739@2 NA|NA|NA S YigZ family PGHMIELC_03167 220668.lp_0735 1.5e-258 898.3 Lactobacillaceae comFA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K02240 M00429 ko00000,ko00002,ko02044 3.A.11.1 Bacteria 1TPZE@1239,3F3TQ@33958,4HB00@91061,COG4098@1,COG4098@2 NA|NA|NA L Helicase C-terminal domain protein PGHMIELC_03168 220668.lp_0736 7.5e-126 456.4 Lactobacillaceae comFC ko:K02242 M00429 ko00000,ko00002,ko02044 Bacteria 1V73S@1239,3F714@33958,4HJ6R@91061,COG1040@1,COG1040@2 NA|NA|NA S Competence protein PGHMIELC_03169 1136177.KCA1_0576 3.5e-100 370.9 Lactobacillaceae hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 ko:K05808 ko00000,ko03009 Bacteria 1V1D5@1239,3F40M@33958,4HFX9@91061,COG1544@1,COG1544@2 NA|NA|NA J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase PGHMIELC_03170 220668.lp_0739 0.0 1543.5 Lactobacillaceae secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1TPEY@1239,3F4DH@33958,4HA22@91061,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane PGHMIELC_03171 220668.lp_0741 3.2e-203 714.1 Lactobacillaceae prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 1TPSB@1239,3F3SN@33958,4H9N2@91061,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA PGHMIELC_03172 220668.lp_0742 1.2e-216 758.8 Lactobacillaceae minJ Bacteria 1TSBA@1239,3F4TP@33958,4HA05@91061,COG0265@1,COG0265@2 NA|NA|NA O Domain present in PSD-95, Dlg, and ZO-1/2. PGHMIELC_03173 220668.lp_0743 1.5e-132 478.8 Lactobacillaceae Bacteria 1TPWS@1239,3FC91@33958,4H9KP@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator PGHMIELC_03174 220668.lp_0744 9.2e-251 872.5 Lactobacillaceae phoR 2.7.13.3 ko:K07636,ko:K07652 ko02020,map02020 M00434,M00459 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQ1H@1239,3F3W2@33958,4HB1B@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase PGHMIELC_03175 220668.lp_0746 3e-151 541.2 Lactobacillaceae pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TQ5X@1239,3F4ER@33958,4HBEB@91061,COG0226@1,COG0226@2 NA|NA|NA P Phosphate PGHMIELC_03176 220668.lp_0747 6.8e-162 576.6 Lactobacillaceae pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02037 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TSPP@1239,3F3NI@33958,4HC9H@91061,COG0573@1,COG0573@2 NA|NA|NA P probably responsible for the translocation of the substrate across the membrane PGHMIELC_03177 220668.lp_0748 1.5e-155 555.4 Lactobacillaceae pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TP74@1239,3F412@33958,4HAKF@91061,COG0581@1,COG0581@2 NA|NA|NA P Phosphate transport system permease protein PstA PGHMIELC_03178 220668.lp_0749 1.1e-147 529.3 Lactobacillaceae pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 iLJ478.TM1261 Bacteria 1TP1M@1239,3F3SY@33958,4HAB1@91061,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system PGHMIELC_03179 220668.lp_0750 1e-139 502.7 Lactobacillaceae pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 iLJ478.TM1261 Bacteria 1TP1M@1239,3F3SY@33958,4HAB1@91061,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system PGHMIELC_03180 220668.lp_0751 8.3e-117 426.4 Lactobacillaceae phoU ko:K02039 ko00000 Bacteria 1URN3@1239,3F46W@33958,4HEU9@91061,COG0704@1,COG0704@2 NA|NA|NA P Plays a role in the regulation of phosphate uptake PGHMIELC_03181 220668.lp_0752 5.8e-49 199.9 Bacteria pspC ko:K03973 ko00000,ko02048,ko03000 Bacteria COG1983@1,COG1983@2 NA|NA|NA KT positive regulation of macromolecule biosynthetic process PGHMIELC_03182 220668.lp_0753 9.2e-54 216.1 Lactobacillaceae yvlD ko:K08972 ko00000 Bacteria 1VF4I@1239,3F7IN@33958,4HNXP@91061,COG1950@1,COG1950@2 NA|NA|NA S Mycobacterial 4 TMS phage holin, superfamily IV PGHMIELC_03183 220668.lp_0754 1.4e-176 625.5 Lactobacillaceae hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06023 ko00000,ko01000 Bacteria 1TP5Z@1239,3F3Z3@33958,4HAXR@91061,COG1493@1,COG1493@2 NA|NA|NA F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion PGHMIELC_03184 220668.lp_0755 1.9e-163 581.6 Lactobacillaceae lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 ko:K03438,ko:K13292 ko00000,ko01000,ko03009 Bacteria 1TPAK@1239,3F42N@33958,4HAT0@91061,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins PGHMIELC_03185 220668.lp_0756 8.5e-182 642.9 Lactobacillaceae gpsA GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 Bacteria 1TQ5P@1239,3F4C8@33958,4HAXW@91061,COG0240@1,COG0240@2 NA|NA|NA I Glycerol-3-phosphate dehydrogenase PGHMIELC_03186 220668.lp_0757 2.1e-171 608.2 Lactobacillaceae galU 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ24@1239,3F45A@33958,4HATY@91061,COG1210@1,COG1210@2 NA|NA|NA M UTP-glucose-1-phosphate uridylyltransferase PGHMIELC_03187 220668.lp_0758 1.9e-124 451.8 Lactobacillaceae yliE GO:0003674,GO:0003824,GO:0008081,GO:0016787,GO:0016788,GO:0042578,GO:0071111 Bacteria 1TVGR@1239,3F5N3@33958,4I2JH@91061,COG2200@1,COG2200@2 NA|NA|NA T Putative diguanylate phosphodiesterase PGHMIELC_03188 220668.lp_0760 6.7e-270 936.0 Lactobacillaceae nox Bacteria 1TPWW@1239,3F449@33958,4H9U7@91061,COG0446@1,COG0446@2 NA|NA|NA C NADH oxidase PGHMIELC_03189 1136177.KCA1_0597 7.3e-163 580.1 Lactobacillaceae Bacteria 1V4ZT@1239,3F5GF@33958,4HG8R@91061,COG3405@1,COG3405@2 NA|NA|NA G Belongs to the glycosyl hydrolase 8 (cellulase D) family PGHMIELC_03190 1136177.KCA1_0598 3.6e-245 854.0 Lactobacillaceae Bacteria 1UKIC@1239,28NCT@1,2ZBFR@2,3F5BU@33958,4HF21@91061 NA|NA|NA PGHMIELC_03191 1136177.KCA1_0599 3.8e-205 721.1 Lactobacillaceae Bacteria 1V2SR@1239,3F58K@33958,4HG5T@91061,COG5298@1,COG5298@2 NA|NA|NA S Protein conserved in bacteria PGHMIELC_03192 1136177.KCA1_0600 6.8e-218 763.1 Lactobacillaceae ydaM Bacteria 1TRCI@1239,3FC1R@33958,4HAAK@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family group 2 PGHMIELC_03193 1136177.KCA1_0601 0.0 1091.6 Lactobacillaceae ydaN GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K20541 ko00000,ko02000 4.D.3.1.6 Bacteria 1V0RQ@1239,28HGC@1,2Z7S8@2,3F5HU@33958,4HF26@91061 NA|NA|NA S Bacterial cellulose synthase subunit PGHMIELC_03194 1136177.KCA1_0602 1e-132 479.6 Lactobacillaceae 2.7.7.65 ko:K18967 ko00000,ko01000,ko02000 9.B.34.1.1 Bacteria 1UMTY@1239,3FB9S@33958,4IU07@91061,COG2199@1,COG2199@2 NA|NA|NA T diguanylate cyclase activity PGHMIELC_03195 220668.lp_0761 1.7e-176 625.2 Lactobacillaceae trxB 1.8.1.9 ko:K00384 ko00450,map00450 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 Bacteria 1TNZS@1239,3F411@33958,4HA4N@91061,COG0492@1,COG0492@2 NA|NA|NA C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family PGHMIELC_03196 220668.lp_0762 2e-109 401.7 Lactobacillaceae yviA Bacteria 1TPNF@1239,3F4F3@33958,4HF15@91061,COG2323@1,COG2323@2 NA|NA|NA S Protein of unknown function (DUF421) PGHMIELC_03197 220668.lp_0763 1.1e-61 242.7 Lactobacillaceae Bacteria 1VG8C@1239,2C9NT@1,32ZGB@2,3F749@33958,4HN0V@91061 NA|NA|NA S Protein of unknown function (DUF3290) PGHMIELC_03198 220668.lp_0764 0.0 1144.0 Lactobacillaceae pgm GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2,5.4.2.8 ko:K01835,ko:K01840 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114,M00549 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP2N@1239,3F457@33958,4HADU@91061,COG1109@1,COG1109@2 NA|NA|NA G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain PGHMIELC_03199 220668.lp_0765 3.3e-132 477.6 Lactobacillaceae yliE GO:0003674,GO:0003824,GO:0008081,GO:0016787,GO:0016788,GO:0042578,GO:0071111 Bacteria 1V6YK@1239,3F5HI@33958,4HIIM@91061,COG2200@1,COG2200@2 NA|NA|NA T Putative diguanylate phosphodiesterase PGHMIELC_03200 220668.lp_0766 1.4e-259 901.7 Lactobacillaceae nox Bacteria 1TPWW@1239,3F4KS@33958,4IEVM@91061,COG0446@1,COG0446@2 NA|NA|NA S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain PGHMIELC_03201 220668.lp_0769 1.1e-103 382.5 Lactobacillaceae ddpX GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009046,GO:0009605,GO:0009991,GO:0016787,GO:0019538,GO:0031667,GO:0042594,GO:0043170,GO:0044238,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.13.22 ko:K07282,ko:K08641 ko01502,ko02020,map01502,map02020 M00651 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Bacteria 1VAFK@1239,3F4HX@33958,4HS7K@91061,COG2173@1,COG2173@2 NA|NA|NA E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide PGHMIELC_03202 220668.lp_0770 1.3e-210 738.8 Lactobacillaceae norA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K08153,ko:K19576,ko:K19578 M00717,M00765 ko00000,ko00002,ko02000 2.A.1.2.10,2.A.1.2.70,2.A.1.2.8 Bacteria 1TS6K@1239,3F4X1@33958,4HB1V@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily PGHMIELC_03203 220668.lp_0771 1.2e-117 429.1 Lactobacillaceae yfbR ko:K07023 ko00000 Bacteria 1TSDU@1239,3F4RZ@33958,4HA8H@91061,COG1896@1,COG1896@2 NA|NA|NA S HD containing hydrolase-like enzyme PGHMIELC_03204 220668.lp_0772 0.0 1306.2 Lactobacillaceae uvrB ko:K03702,ko:K08999 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TPKB@1239,3F3XM@33958,4HB81@91061,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage PGHMIELC_03205 220668.lp_0773 0.0 1890.5 Lactobacillaceae uvrA ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TPIJ@1239,3F4TZ@33958,4HAW9@91061,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate PGHMIELC_03206 220668.lp_0774 6.7e-89 333.2 Lactobacillaceae luxS GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300 Bacteria 1V1CH@1239,3F4W2@33958,4HFPR@91061,COG1854@1,COG1854@2 NA|NA|NA H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) PGHMIELC_03207 220668.lp_0775 1.8e-231 808.1 Lactobacillaceae argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.argG,iSB619.SA_RS04675 Bacteria 1TP3X@1239,3F46X@33958,4HA1E@91061,COG0137@1,COG0137@2 NA|NA|NA E Belongs to the argininosuccinate synthase family. Type 1 subfamily PGHMIELC_03208 220668.lp_0776 1.1e-264 918.7 Lactobacillaceae argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TNZ6@1239,3F4PF@33958,4HB24@91061,COG0165@1,COG0165@2 NA|NA|NA E argininosuccinate lyase PGHMIELC_03209 220668.lp_0778 9.3e-87 326.2 Lactobacillaceae Bacteria 1VJ0U@1239,3FB5N@33958,4HQJ0@91061,COG3247@1,COG3247@2 NA|NA|NA S Short repeat of unknown function (DUF308) PGHMIELC_03210 220668.lp_0779 1.1e-161 575.9 Lactobacillaceae rapZ GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K06958 ko00000,ko03019 Bacteria 1TPS4@1239,3F4NY@33958,4H9KM@91061,COG1660@1,COG1660@2 NA|NA|NA S Displays ATPase and GTPase activities PGHMIELC_03211 220668.lp_0780 2.9e-190 671.0 Lactobacillaceae ybhK Bacteria 1TPNV@1239,3F4D5@33958,4HA0Z@91061,COG0391@1,COG0391@2 NA|NA|NA S Required for morphogenesis under gluconeogenic growth conditions PGHMIELC_03212 220668.lp_0781 3.7e-168 597.4 Lactobacillaceae whiA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944 ko:K09762 ko00000 Bacteria 1TP2X@1239,3F4AB@33958,4HB4H@91061,COG1481@1,COG1481@2 NA|NA|NA K May be required for sporulation PGHMIELC_03213 220668.lp_0783 4e-306 1056.6 Lactobacillaceae oppA ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F3JE@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substratebinding protein PGHMIELC_03214 220668.lp_0785 1e-176 625.9 Lactobacillaceae 1.1.1.26 ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko01000 Bacteria 1TPCX@1239,3F4Z6@33958,4HASY@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family PGHMIELC_03215 220668.lp_0786 3e-102 377.9 Lactobacillaceae clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 1TQ91@1239,3F3M0@33958,4HA8J@91061,COG0740@1,COG0740@2 NA|NA|NA O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins PGHMIELC_03217 220668.lp_0787 4.2e-245 853.6 Lactobacillaceae rpoN GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Bacteria 1TQ0H@1239,3F4R8@33958,4HA8T@91061,COG1508@1,COG1508@2 NA|NA|NA K Sigma-54 factor, core binding domain PGHMIELC_03218 220668.lp_0788 7.3e-189 666.4 Lactobacillaceae cggR ko:K05311 ko00000,ko03000 Bacteria 1TP62@1239,3F53Y@33958,4HAE6@91061,COG2390@1,COG2390@2 NA|NA|NA K Putative sugar-binding domain PGHMIELC_03219 220668.lp_0789 2.6e-191 674.5 Lactobacillaceae gap GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009986,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0022610,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044464,GO:0044650,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:0140030,GO:0140032,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iJR904.b1416,iJR904.b1417 Bacteria 1TNYU@1239,3F3JS@33958,4H9NS@91061,COG0057@1,COG0057@2 NA|NA|NA G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family PGHMIELC_03220 220668.lp_0790 8.1e-224 782.7 Lactobacillaceae pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iSB619.SA_RS04145 Bacteria 1TP3H@1239,3F3SC@33958,4H9R3@91061,COG0126@1,COG0126@2 NA|NA|NA F Belongs to the phosphoglycerate kinase family PGHMIELC_03221 220668.lp_0791 1.2e-137 495.7 Lactobacillaceae tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS19265 Bacteria 1TP2F@1239,3F494@33958,4HAPT@91061,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) PGHMIELC_03222 220668.lp_0792 1.6e-249 868.2 Lactobacillaceae eno GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 1TP2S@1239,3F3JP@33958,4HAKI@91061,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis PGHMIELC_03223 220668.lp_0793 4.1e-132 477.6 Lactobacillaceae Bacteria 1U5IR@1239,29WGZ@1,30I32@2,3F61Q@33958,4IF9H@91061 NA|NA|NA PGHMIELC_03224 220668.lp_0794 9.6e-294 1015.4 Lactobacillaceae clcA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006821,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015672,GO:0015698,GO:0015706,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0031404,GO:0034220,GO:0042802,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 ko:K03281,ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4,2.A.49 iAF1260.b0155,iB21_1397.B21_00153,iBWG_1329.BWG_0148,iE2348C_1286.E2348C_0162,iEC042_1314.EC042_0155,iEC55989_1330.EC55989_0149,iECBD_1354.ECBD_3463,iECDH10B_1368.ECDH10B_0135,iECDH1ME8569_1439.ECDH1ME8569_0149,iECD_1391.ECD_00154,iECIAI1_1343.ECIAI1_0153,iECO103_1326.ECO103_0155,iECSE_1348.ECSE_0156,iECUMN_1333.ECUMN_0152,iECW_1372.ECW_m0152,iEKO11_1354.EKO11_3761,iETEC_1333.ETEC_0151,iEcDH1_1363.EcDH1_3447,iEcE24377_1341.EcE24377A_0160,iEcolC_1368.EcolC_3504,iJO1366.b0155,iSSON_1240.SSON_0167,iUMNK88_1353.UMNK88_159,iWFL_1372.ECW_m0152,iY75_1357.Y75_RS00790,iZ_1308.Z0166 Bacteria 1TPX0@1239,3F3MU@33958,4HD2H@91061,COG0038@1,COG0038@2,COG0569@1,COG0569@2 NA|NA|NA P chloride PGHMIELC_03225 220668.lp_0795 1.2e-30 138.7 Lactobacillaceae secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VEQR@1239,3F7IQ@33958,4HNKC@91061,COG1314@1,COG1314@2 NA|NA|NA U Preprotein translocase PGHMIELC_03226 220668.lp_0796 1.3e-139 502.3 Lactobacillaceae est GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.1 ko:K03928 ko00000,ko01000 Bacteria 1TQ7X@1239,3F5XW@33958,4HBE6@91061,COG1647@1,COG1647@2 NA|NA|NA S Serine aminopeptidase, S33 PGHMIELC_03227 220668.lp_0797 0.0 1450.3 Lactobacillaceae rnr ko:K12573,ko:K12585 ko03018,map03018 M00391 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 1TQ1G@1239,3F4EC@33958,4HBBH@91061,COG0557@1,COG0557@2 NA|NA|NA J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs PGHMIELC_03228 220668.lp_0799 9.3e-83 312.8 Lactobacillaceae smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 ko:K03664 ko00000 Bacteria 1V3IJ@1239,3F65B@33958,4HGZX@91061,COG0691@1,COG0691@2 NA|NA|NA J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA PGHMIELC_03229 220668.lp_0800 0.0 2648.2 Lactobacillaceae 3.4.21.72 ko:K01347 ko00000,ko01000,ko01002,ko02000,ko02044 1.B.12.3 Bacteria 1TT3P@1239,3F4YY@33958,4I28K@91061,COG3209@1,COG3209@2,COG4886@1,COG4886@2 NA|NA|NA M Bacterial Ig-like domain (group 3) PGHMIELC_03230 220668.lp_0802 1.5e-256 891.7 Lactobacillaceae glnP ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TQUG@1239,3F4HA@33958,4HAJ5@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2 NA|NA|NA P ABC transporter PGHMIELC_03231 60520.HR47_07585 1.2e-132 479.2 Lactobacillaceae glnQ 3.6.3.21 ko:K02028,ko:K10038 ko02010,map02010 M00227,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.2 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein PGHMIELC_03232 220668.lp_0804 4.6e-105 387.1 Lactobacillaceae yxjI ko:K21429 ko00000,ko01002 Bacteria 1V8EY@1239,3F698@33958,4HMMS@91061,COG4894@1,COG4894@2 NA|NA|NA PGHMIELC_03233 220668.lp_0805 4.4e-155 553.9 Lactobacillaceae ycsE Bacteria 1V5FB@1239,3F58Y@33958,4HGY8@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase PGHMIELC_03234 220668.lp_0806 1.6e-136 491.9 Lactobacillaceae ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPSN@1239,3F3W0@33958,4HBTR@91061,COG0692@1,COG0692@2 NA|NA|NA L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine PGHMIELC_03235 220668.lp_0807 1.4e-178 632.1 Lactobacillaceae pta 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028,ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 iSB619.SA_RS03155 Bacteria 1TPQ0@1239,3F3MW@33958,4H9VH@91061,COG0280@1,COG0280@2 NA|NA|NA C phosphate acetyltransferase PGHMIELC_03236 220668.lp_0809 5e-81 307.0 Lactobacillaceae ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.1.221,5.1.1.1 ko:K01775,ko:K06925,ko:K07102 ko00473,ko00520,ko01100,ko01502,map00473,map00520,map01100,map01502 R00401,R08968,R11024 RC00002,RC00078,RC00285 ko00000,ko00001,ko01000,ko01011,ko03016 Bacteria 1V6CV@1239,3F3MR@33958,4HIIF@91061,COG0802@1,COG0802@2 NA|NA|NA O Hydrolase, P-loop family PGHMIELC_03237 220668.lp_0810 8.1e-88 329.7 Lactobacillaceae 2.3.1.128,2.3.1.178 ko:K03790,ko:K03825,ko:K06718 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06978 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 1UI5U@1239,3FBSC@33958,4ISEP@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain PGHMIELC_03238 220668.lp_0811 4.3e-100 370.5 Lactobacillaceae dnaQ 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1V57H@1239,3F42Z@33958,4HI1V@91061,COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III PGHMIELC_03239 220668.lp_0812 2.8e-153 547.7 Lactobacillaceae xth GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPFB@1239,3F4GK@33958,4HAIU@91061,COG0708@1,COG0708@2 NA|NA|NA L exodeoxyribonuclease III PGHMIELC_03240 220668.lp_0813 1.9e-156 558.5 Lactobacillaceae yceM 1.1.1.18,1.1.1.369 ko:K00010,ko:K03810 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 R01183,R09951 RC00182 ko00000,ko00001,ko01000 Bacteria 1UZRV@1239,3F4BX@33958,4HEWB@91061,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold PGHMIELC_03241 220668.lp_0814 6.2e-168 596.7 Lactobacillaceae murB 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 Bacteria 1TP3W@1239,3F40T@33958,4HAD8@91061,COG0812@1,COG0812@2 NA|NA|NA M Cell wall formation PGHMIELC_03242 220668.lp_0815 0.0 1271.1 Lactobacillaceae yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 1TR4G@1239,3F42V@33958,4HBJR@91061,COG0025@1,COG0025@2 NA|NA|NA P Sodium proton antiporter PGHMIELC_03243 220668.lp_0816 1.3e-90 339.0 Lactobacillaceae Bacteria 1U5EC@1239,3F5QD@33958,4IF5S@91061,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein PGHMIELC_03244 220668.lp_0817 2.5e-121 441.4 Lactobacillaceae Bacteria 1VFQS@1239,3F5AV@33958,4HNWH@91061,COG4330@1,COG4330@2 NA|NA|NA S Protein of unknown function (DUF1361) PGHMIELC_03245 220668.lp_0818 2.7e-149 534.6 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 ko00000,ko01000 Bacteria 1TPRW@1239,3F4N3@33958,4H9XZ@91061,COG1624@1,COG1624@2 NA|NA|NA S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria PGHMIELC_03246 220668.lp_0819 1.6e-129 469.2 Lactobacillaceae ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 Bacteria 1TSIV@1239,3F41C@33958,4HD8Y@91061,COG4856@1,COG4856@2 NA|NA|NA S YbbR-like protein PGHMIELC_03247 220668.lp_0820 1.6e-252 878.2 Lactobacillaceae glmM GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 R02060 RC00408 ko00000,ko00001,ko01000 iSB619.SA_RS11275,iSBO_1134.SBO_3206 Bacteria 1TP1X@1239,3F3W5@33958,4HB16@91061,COG1109@1,COG1109@2 NA|NA|NA G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate PGHMIELC_03248 220668.lp_0822 0.0 1172.1 Lactobacillaceae glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 iNJ661.Rv3436c,iSB619.SA_RS11245,iYO844.BSU01780 Bacteria 1TPGU@1239,3F467@33958,4H9R4@91061,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source PGHMIELC_03249 220668.lp_0823 4.5e-123 447.2 Lactobacillaceae yliE GO:0003674,GO:0003824,GO:0008081,GO:0016787,GO:0016788,GO:0042578,GO:0071111 Bacteria 1U6DK@1239,3F7NQ@33958,4IG5B@91061,COG2200@1,COG2200@2 NA|NA|NA T EAL domain PGHMIELC_03250 220668.lp_0824 6.4e-148 530.0 Lactobacillaceae 3.1.3.23 ko:K07757 R00804 ko00000,ko01000 Bacteria 1TVJM@1239,3F5I5@33958,4I37C@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase PGHMIELC_03251 220668.lp_0825 3.1e-104 384.4 Lactobacillaceae Bacteria 1VH11@1239,3F4NX@33958,4IEW1@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family PGHMIELC_03252 220668.lp_0826 1.6e-207 728.4 Lactobacillaceae galM 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQGJ@1239,3F48R@33958,4HADZ@91061,COG2017@1,COG2017@2 NA|NA|NA G Catalyzes the interconversion of alpha and beta anomers of maltose # 3047 queries scanned # Total time (seconds): 5.65480399132 # Rate: 538.83 q/s