LOCUS       c00007_JABFHE0..       12732 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JABFHE010000016.1 Bacillus subtilis strain WS1A
            NODE_16_length_89853_cov_53.0098, whole genome shotgun sequence.
ACCESSION   JABFHE010000016
VERSION     JABFHE010000016
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-21 00:00:45
            Original ID  :: JABFHE010000016.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 51530
            Orig. end    :: 64262
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12732
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[56530:59262]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7732
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12732
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12732
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             46..1431
                     /gene_functions="transport (smcogs) SMCOG1169:sugar
                     transport protein (Score: 441.1; E-value: 6.8e-134)"
                     /gene_kind="transport"
                     /locus_tag="ctg7_54"
                     /transl_table=11
                     /translation="VKKDTRKYMIYFFGALGGLLYGYDTGVISGALLFINNDIPLTTLT
                     EGLVVSMLLLGAIFGSALSGTCSDRWGRRKVVFVLSIIFIIGALACAFSQTIGMLIASR
                     VILGLAVGGSTALVPVYLSEMAPTKIRGTLGTMNNLMIVTGILLAYIVNYLFTPFEAWR
                     WMVGLAAVPAVLLLIGIAFMPESPRWLVKRGREEEARRIMNITHDPKDIEMELAEMKQG
                     EAEKKETTLSVLKAKWIRPMLLIGVGLAIFQQAVGINTVIYYAPTIFTKAGLGTSASAL
                     GTMGIGVLNVIMCITAMILIDRVGRKKLLIWGSVGITLSLAALSGVLLTLGLSASTAWM
                     TVVFLGVYIVFYQATWGPVVWVLMPELFPSKARGAATGFTTLVLSAANLIVSLVFPLML
                     SAMGIAWVFMVFSVICLLSFFFAFYMVPETKGRSLEEIEASLKNRFKKKKSTQNQMLNE
                     RTL"
     CDS             complement(1474..3354)
                     /locus_tag="ctg7_55"
                     /transl_table=11
                     /translation="VAKKEFKAESKRLLDMMINSIYTQKEIFLRELISNSSDAIDKIYY
                     KALTDDALTFDKDSYYIKVAADKDARTLTISDTGIGMTKDELEQHLGTIAKSGSLAFKK
                     ENELKDGHDIIGQFGVGFYAAFMVADVVTVISKALGSEEAYKWESAGADGYTIEPCEKD
                     SVGTDIILKIKENTEDDSYDEFLEEYRLKAIIKKYSDFIRYPIKMDTTINKPKEGSENE
                     FEEVQEEQTVNSMVPIWRKNKSELTDEDYEKFYAEKHYGFDKPLTHVHISVDGAVRYNA
                     ILFVPENMPFDYYSKEYEKGLELYSNGVLIMNKCADLLPDHFSFVKGMVDSEDLSLNIS
                     REMLQHDRQLKLIAKNISKKIKSELQSLLKKDREKYETFYKSFGRQLKFGVYNDFGANK
                     DQLKDLLLFYSSKEKKLVSLDEYVSRMPEEQKYIYYATGDSYDRIEKLPQTEMVADKGY
                     EILYFTEDIDEFAIKMLASYQEKEFKSVSSGDLGIDTDEDQKQSEEEESKYKDLFEEMK
                     NILSDKVKNVRISKRLKSHPVCLAADGEVTIEMEKILNAMPDSQNVKAEKVLEINPNHE
                     VFQTLQDAFEQDKEKLSLYTNLLYNQALLIEGLPIQDPVEFTNNICKVMV"
     CDS             complement(3522..3773)
                     /locus_tag="ctg7_56"
                     /transl_table=11
                     /translation="LKVQHKKELKFYCIVTIPSAFVVLTVISFLLQEITFPVTASAFLN
                     ASWHNLLFLIPFGLFFYPVHIWMKREFGRWNDTEKKRG"
     CDS             3890..4699
                     /NRPS_PKS="Domain: PKS_KR (7-160). E-value: 2.3e-09. Score:
                     29.1. Matches aSDomain: nrpspksdomains_ctg7_57_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     247.6; E-value: 2.2e-75)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_57"
                     /sec_met_domain="adh_short (E-value: 2.8e-33, bitscore:
                     107.9, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.4e-37, bitscore:
                     122.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRLENKTAVITGAATGIGQATAEVFANEGARVIIGDINKDQMEE
                     TVDAIRKNGGQAESFHLDVSDENSVKAFADQIKDACGTIDILFNNAGVDQEGGKVHEYP
                     VDLFDRIIAVDLRGTFLCSKYLIPLMLENGGSIINTSSMSGRAADLDRSGYNAAKGGIT
                     NLTKAMAIDYARNGIRVNSISPGTIETPLIDKLAGTKEQEMGEKFREANKWVTPLGRLG
                     QPKEMATVALFLASDDSSYVTGEDITADGGIMAYTWPGKMLIDEKWK"
     aSDomain        3911..4369
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg7_57_PKS_KR.1"
                     /evalue="2.30E-09"
                     /label="ctg7_57_PKS_KR.1"
                     /locus_tag="ctg7_57"
                     /protein_end="160"
                     /protein_start="7"
                     /score="29.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TAVITGAATGIGQATAEVFANEGARVIIGDINKDQMEETVDAIRK
                     NGGQAESFHLDVSDENSVKAFADQIKDACGTIDILFNNAGVDQEGGKVHEYPVDLFDRI
                     IAVDLRGTFLCSKYLIPLMLENGGSIINTSSMSGRAADLDRSGYNAAKG"
     aSModule        3911..4369
                     /domains="nrpspksdomains_ctg7_57_PKS_KR.1"
                     /incomplete
                     /locus_tags="ctg7_57"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       3917..3994
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg7_57_0001"
                     /evalue="1.80E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg7_57"
                     /protein_end="35"
                     /protein_start="9"
                     /score="17.4"
                     /tool="antismash"
                     /translation="VITGAATGIGQATAEVFANEGARVII"
     CDS             5001..5198
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_58"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 6.4e-15,
                     bitscore: 47.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKELSNLELEKVEGGNWQNVTKNTLFAAADGAAIGGMFGGPAGAF
                     VGAHYGAAAYAIGYALDHRK"
     CDS             5222..5467
                     /locus_tag="ctg7_59"
                     /transl_table=11
                     /translation="MNNLENKSFEVLSDNQLELVEGGSGYGDGVAGGLTGGAILGGVVK
                     GAQNGAKYGRLGGAWGVAAGVVVGGAIGGYLGYKGA"
     CDS             5549..7732
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 289.2; E-value:
                     1.1e-87)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_60"
                     /sec_met_domain="TIGR01193 (E-value: 9e-239, bitscore:
                     787.0, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.3e-46, bitscore:
                     149.5, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFFKKYQYVKQIDEKDCGAACLATILKHYGSKLSINKIRDIAGTD
                     KQGTSALGLVRAAEQLGFSAKGVKADKTALEEPFTLPAIAHIILNGQLLHYVVIHKITK
                     DQIIIADPGRGIIKYTKKEFLEVWTGILILLTPSETYKIHVETSTIRSDIFKLILHQKS
                     LIIHTILASFIITVFGIMGTFYFQTVIDEILPNRLNSTLHILSFGLIIMYLFKVLLTAF
                     RQYLMILLGQKLSISIMFGYFKHVLSLPMKFFSTRKIGEIISRFNDASKVIDAIISASL
                     SVVLDTVMLVMVGIFLYLQNTTLFLITLAFIPFYVLTVWFFMKPYESINNTEMENNAQL
                     TSKIVETLNGIETIKAYNAEYMMSYETEKRFVKYLRSAFKHGVIDNLQNSIKMFLDLAS
                     GAFILWIGSTQVMKGTLSIGQLITYNALLTYFLNPLQNIIGLQSKLQSASVASKRLGEI
                     LEVEHEIKDKDAQITTPGSINGPIEFIKINFRYGTRRLILKDITLRIDKGEKVAFIGES
                     GSGKSTLTKLLMKFYTAESGDILINGYHINDIHAHSLRESISYIPQESHFIQGSIFENL
                     LLGNSGSFTFEEIIEVCKQTNVHDFVNDLPMRYDTLVEENGSNLSGGQKQRLAIARALL
                     RKPNILIMDESTSNLDTTTEQGISKMIYDQTVGITTIIIAHRLSTIMNCDKIFVMENGE
                     IIEYGNHNDLLKKKGKYYELWENQMPSRGMVTI"
     CDS             7733..9202
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 70.2; E-value:
                     2.4e-21)"
                     /gene_kind="transport"
                     /locus_tag="ctg7_61"
                     /transl_table=11
                     /translation="MKRNFFNLHDLKDSREFYESKPKPIGVFFTYILIALLIACIVFSF
                     YGKKEVILKTTADIQYTKPNSNVTNEVAGKVKTVDIKQVDKVKKGDTLLTLDNTEIQAQ
                     KRAVKADIKDLKEQAALNKTLKKSIENDKNLFSEDDHWGYQDQYLSYEKQSILLESSKE
                     NAKTQQKKLKKQKESIKDSLDKTKNKVKLKLQRISDLQDSIKNNKSFAKQDDKYSSYYN
                     SYQTNKQNVEQQLDDLRKMKDELDKNRFSQQKENLNGQLESLKQDMLVKLSEEKDELNQ
                     SLDEINSSIKSDDSDSDSDNSEETNYKLSIEQLKTNLLNQTSQKQTDLQTTLKSKEDDL
                     KMIDLQLEKYKIKAASDGYVNVLTNISPGDNLQAGTAILTIIPDKEKLKANIYIPSHEI
                     TNINEKDEVRFHIENTNQTIKGVITKISPDSISDQNGQKFYIAESTIEKNKVMNDNGST
                     LHLKNGMQTDVSIIVDSKRYIDYLLEILHLQ"
     CDS             complement(9720..10862)
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 41.6; E-value: 3e-12)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg7_62"
                     /transl_table=11
                     /translation="VPESAEAQVKQALLALLEERDMQHITMKEIAERAKVSRGTLYLYY
                     EDKFSIIEDVIEDMKEGLGKALFDAFSHMDTLHLNKKRQTVHPTLSFVHEHRSFFSVMM
                     NRGHFHRFFRDVFQQDVLLTPVHVNLTPIEREIYGHYRALYTYAIILYWLNEDAAAAPE
                     AISQKVWELVSQKRFYWLFGQAVPGEREKGKPIDRRVVRTREALQQAFLDVLAEKQDYA
                     GITISDITRKSNIRRATFYDHYANKEELLQTMIQRSCAEIIDHLTIASSPNELSFEEAE
                     EVLAGLLSALDRMPIVHLLNRDWVVPHVIPELLKALESFYLHQQTNIPAEKKLYAYYVS
                     AMIIGLILYRLDEGKAHAPEVLARKFLQFLDVKKYKVVLL"
     CDS             11005..12342
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 303.3; E-value:
                     3.9e-92)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_63"
                     /transl_table=11
                     /translation="MEQKVKDDIQRVFQLQKKQQKALRASTAEQRKEKLQRFLDSVIAH
                     EEEIIEAIRKDVRKPYHEVKKAEIEGTKKAIRDNMNNLEQWMAPKEVGSSLSPEANGIL
                     MYEPKGVTLILGPWNYPFMLTMAPLAASLAAGNSAIVKLSDFTMNTSNIAAKVIRDAFD
                     EKEVAIFEGEVEVATELLDQPFDHIFFTGSTNVGKIVMTAAAKHLASVTLELGGKSPTI
                     IDSEYDLMDAAKKIAVGKFVNAGQTCIAPDYLFIKKDVQDRFAGILQTIVNAGFMEDDH
                     TPDRSKFTQIVNDRNFNRVKDLFDDAIEKGAEVVFGGVFDASDRTISPTVLKNVTPDMK
                     IMQEEIFAPILPMMNYEDIDEVIDYVNDRDKPLALYVFSKNQDLIDNVLQHTTSGNAAI
                     NDVVVHFSDVNLPFGGVNTSGIGSYHGVYGFKEFSHEKGVFIQASK"
ORIGIN
        1 tatttttaga tactcattgg ctcaacaact gaggaggaga catttgtgaa gaaagacaca
       61 aggaaatata tgatctactt tttcggcgct ttagggggac tgctatatgg ttacgataca
      121 ggtgttatct ccggagcact cctgtttatc aataacgata ttcctttaac gacattgaca
      181 gaaggattgg ttgtcagcat gctgctcctt ggcgcgattt tcggttctgc cttgagcggc
      241 acatgctcag accgctgggg caggagaaag gttgtatttg tcctttccat catttttatt
      301 atcggtgcgc tcgcttgcgc attttctcaa acaatcggca tgctgattgc atctagggtg
      361 atactcgggt tggccgtcgg cggttcaacg gcgcttgtgc ccgtgtatct ttccgaaatg
      421 gcaccgacga aaattcgcgg gacactcggc acaatgaaca acttaatgat tgtcaccggg
      481 attttgctcg cctatatcgt gaactacctg ttcacaccgt ttgaagcgtg gcgctggatg
      541 gtcggtctgg ccgcagtgcc tgccgtgctt ctattaatcg gcatcgcgtt catgccagaa
      601 tcgccaagat ggctcgtgaa gcgcggccgt gaagaagaag cgagacgaat catgaacatc
      661 actcatgatc caaaagacat cgaaatggaa ttggcagaga tgaagcaagg agaagcagag
      721 aaaaaagaaa cgacactcag cgtcctaaaa gccaaatgga ttcgccccat gcttctgatt
      781 ggcgtcggcc tagctatttt ccagcaggct gtcggcatta acacggtcat ctactacgcg
      841 ccgaccattt ttacgaaggc cggtcttggc acgtcagctt ccgcactcgg cacaatggga
      901 atcggcgtcc ttaacgtcat catgtgtatc actgccatga tcttaattga ccgtgtcgga
      961 cgcaaaaaac ttctgatctg gggaagtgtc ggcatcacac tgagccttgc tgctttatca
     1021 ggcgtgctcc tgacattggg gctttccgca tcaacagcgt ggatgacagt agtctttctc
     1081 ggcgtctata tcgtctttta ccaggcgaca tggggtcctg tagtgtgggt gctcatgcct
     1141 gagctcttcc cgtccaaagc gcgcggagcc gcgacagggt tcacgacttt ggtgttatcg
     1201 gcagccaacc tgatcgtgtc gctcgtcttc ccgctgatgc taagcgcaat gggcatcgca
     1261 tgggtcttta tggttttctc agtcatttgt cttctctcat ttttcttcgc tttctacatg
     1321 gtgccggaaa ccaaagggcg aagcttggag gaaattgaag caagcctgaa aaaccggttt
     1381 aaaaagaaga aaagcaccca aaaccaaatg ctgaatgagc gtacattata aaaaaaagga
     1441 atcgtctcct tatgggacga ttcctttttc tgtttacacc atgaccttgc aaatattgtt
     1501 cgtaaattcc acagggtcct gaatcggcag gccttcgatg agaagcgcct gattgtacag
     1561 aaggtttgtg tacaggctca gcttctcttt atcttgttca aacgcgtcct gcagcgtttg
     1621 aaatacctcg tgatttgggt tgatctccag cactttttct gccttcacat tttggctgtc
     1681 aggcatcgcg tttaagattt tttccatctc aattgtcact tcgccgtcag cagcaaggca
     1741 gactggatgt gatttaagcc gttttgagat tctgacgttt ttcactttgt ctgacagaat
     1801 gtttttcatt tcctcaaaca gatccttata cttgctttcc tcttcctcgg actgcttttg
     1861 atcctcatcc gtgtctatgc caaggtctcc gcttgatacg gacttgaatt ctttttcctg
     1921 ataagaagcc agcattttaa ttgcaaactc atcgatgtcc tcagtaaagt agaggatttc
     1981 atagcctttg tccgccacca tttccgtttg cggcagtttc tcaatgcggt cgtaagaatc
     2041 accggtcgcg taataaatgt atttctgctc ctctggcatt ctggaaacat actcgtctaa
     2101 gctgaccagt tttttctctt ttgaagagta gaataatagg agatccttca attgatcctt
     2161 attcgcgcca aaatcattgt acacgccgaa tttcagctgt ctgccgaacg acttgtagaa
     2221 cgtctcgtat ttctcgcggt cttttttcaa caggctttgc agctcgcttt tgattttctt
     2281 gctgatgttt ttcgcgatca gcttcagctg gcggtcatgc tgcagcattt ctctggaaat
     2341 attcagcgac agatcctcag aatcgaccat gcccttcaca aagctgaagt ggtccggtag
     2401 caggtctgcg cacttattca tgatcagcac gccattggaa tacagctcca agcctttctc
     2461 atattccttg gaatagtagt cgaacggcat gttttcaggg acgaatagaa ttgcgttgta
     2521 gcgaacggct ccatccacac tgatatgaac gtgtgtcagc ggtttatcaa acccgtaatg
     2581 cttctcagca tagaattttt cataatcctc atctgtcagc tcgcttttgt tttttctcca
     2641 gatcggcacc atgctgttga ccgtctgctc ttcctgcacc tcttcaaatt cattttcgct
     2701 tccttccttc ggcttattaa tggtggtatc cattttgatc ggatagcgaa tgaagtcgga
     2761 gtacttctta atgatcgctt ttaaacgata ttcctctaaa aactcgtcat agctgtcatc
     2821 ttctgtgttc tctttgattt tcaggataat gtctgtaccg acagaatcct tttcacacgg
     2881 ctcaatcgta tagccgtctg cacccgcaga ctcccattta taagcctctt cgctgccaag
     2941 cgctttactg atgactgtca cgacatcggc aaccataaat gccgcgtaaa aaccaacacc
     3001 gaactgcccg ataatgtcat gtccgtcttt cagctcgttt tcctttttaa acgcgaggga
     3061 accgcttttt gcaattgttc caagatgctg ttcaagctca tcctttgtca ttccgatccc
     3121 cgtatcagag atggttaatg ttctcgcatc tttgtcagct gcgaccttta tgtagtaact
     3181 atctttatca aacgtaagcg catcgtccgt aagcgctttg taatagattt tgtcaatcgc
     3241 atcactcgaa ttggagatta actcgcgcag gaaaatttct ttttgggtat aaatggagtt
     3301 aatcatcata tccagcaagc gtttagactc tgctttaaac tcttttttcg ccactcttga
     3361 tcgctccttt accattatgt aaaccctttt cagcatctat ttatcacata agatgacaat
     3421 tgtcaattag attgatagat gcatatatat gtaaatttaa cattagttgg atttgttttc
     3481 actctttttc tcactcattc tcataaaaaa gagaggcttc atcatcctct ctttttttct
     3541 gtgtcattcc agcggccaaa ctcccgcttc atccaaatat gcaccgggta gaaaaacaaa
     3601 ccgaacggta tcaaaaacaa aagattatgc catgaagcat tcagaaatgc gcttgcagtc
     3661 accggaaacg taatctcttg caataaaaaa gagatgacag tcagcacaac aaatgcagat
     3721 ggaatggtca cgatgcaata aaacttgagc tccttcttat gctgtacctt caaacataca
     3781 aacctcccaa caatttctaa ttcatcttaa catatgctgg cctttctttt ctcgcatgtt
     3841 tatcactgca catagcggga agacaaatag aaaaaggagg tctcgtatca tgggaagact
     3901 tgaaaacaaa acagcagtga tcacaggcgc cgcgacaggc attgggcaag cgacggcaga
     3961 ggtttttgcc aatgaaggcg cgcgtgtgat catcggagat atcaataaag atcaaatgga
     4021 agaaacagtt gacgcaatca gaaaaaacgg aggacaggcc gaatcctttc acctcgatgt
     4081 gtcagatgaa aacagtgtga aagcatttgc tgatcaaatc aaggatgcat gcggaacgat
     4141 tgatattctg tttaataatg ccggcgttga tcaggaaggc ggaaaggtgc acgaatatcc
     4201 ggttgacctg tttgaccgca ttatcgctgt cgacctgcgc ggcacattcc tttgcagcaa
     4261 atatctgatt ccgctcatgc tcgaaaatgg aggctccatc atcaacacct cctccatgtc
     4321 aggccgtgcc gcggaccttg accgctcggg ctacaacgca gcaaaaggcg gcatcaccaa
     4381 cctgacaaaa gcgatggcga tcgactacgc acggaacggc atccgcgtca attccatttc
     4441 accgggtacg atcgaaaccc cgctgattga caaattagca ggcaccaaag aacaggaaat
     4501 gggtgaaaaa ttccgcgaag ccaacaaatg ggtcacgccg ctcggccgcc tcggccagcc
     4561 gaaggaaatg gcgacagtgg ccctgttcct cgcgtcagac gacagctcat acgtcacagg
     4621 agaggacatc accgcagacg gcggcatcat ggcatataca tggcctggga agatgctgat
     4681 tgatgagaag tggaaataaa attcagatga ttcattaaga gagggtggat agaaatctgc
     4741 cctcttttat tgaatttagg attagcattt caaaaatctt atacagtaga ttattagaac
     4801 attatagtaa taatccaatt tatcctcttg aatatacatt taaagtcaag tcgtttgtcc
     4861 aaaagaaatt aaataaactc caacatcttc atcatctaaa agtaagttaa ttaccaaaga
     4921 aaaatatagt aaatgatatt gattttacca ataatttata ctagaataac taggaaacca
     4981 gtacaaaagg agggttattt atgaaagaat tatctaattt agaattagaa aaagtggaag
     5041 gcggaaactg gcaaaatgtt acgaagaata ctctatttgc tgctgctgat ggagctgcaa
     5101 tcggaggaat gtttggtggt ccagcgggcg cttttgttgg ggctcattat ggagctgctg
     5161 catacgctat tggttacgct ttggatcaca gaaaataata caatgttagg ggaatataca
     5221 tatgaataat ttagaaaata aaagttttga agtcttatct gataatcagc ttgagttagt
     5281 agaagggggt tcaggctatg gtgatggtgt agctggagga ctcacaggag gagctatact
     5341 aggcggtgta gtaaaagggg cccaaaatgg cgcgaaatat ggaagactag gtggagcatg
     5401 gggagttgcc gctggtgttg tagttggagg agccatcggt ggttacttag gatataaagg
     5461 ggcttaaaaa tcccttaact taagacgatc tgtttgatta acagattgtc tttctttttt
     5521 aaaataatta gaatcatgga gtatttagat gttctttaaa aagtaccaat atgtaaaaca
     5581 aattgatgaa aaagactgtg gagcagcttg tctagccact atattgaagc attacggctc
     5641 caaattatca ataaataaaa ttcgagatat tgcgggaaca gataaacaag gcacaagcgc
     5701 acttggacta gtcagagcag ctgaacaatt aggcttttca gcaaaaggag taaaagctga
     5761 caaaacagct ttagaagaac cctttacact gccggctatt gcacatatca ttcttaatgg
     5821 acaattatta cattatgttg ttattcataa aattacaaaa gaccagatta tcattgcaga
     5881 tcctggccgc ggaatcatta agtacacaaa aaaagaattt ttagaggttt ggacaggaat
     5941 cttaatttta ctgactcctt ctgaaacata taagatccat gtagagacca gtactatacg
     6001 aagtgatata ttcaaattaa tacttcatca aaaatcattg atcatccaca caattttagc
     6061 atcctttatc attacagttt tcggtattat ggggactttt tattttcaaa cggtcattga
     6121 tgagatttta ccaaatagat tgaatagcac gttacatata ctttcattcg gcctcatcat
     6181 tatgtactta tttaaagtcc ttttaacagc ctttaggcaa tatttaatga tattattggg
     6241 ccaaaaatta agtatttcaa taatgtttgg ttatttcaaa catgtactta gcttaccgat
     6301 gaagtttttt agcactagaa agatcgggga gattatatct agatttaatg atgctagcaa
     6361 agtaattgat gctattatta gcgcctctct atcagtagta cttgatacag taatgcttgt
     6421 aatggtaggc atctttttat atctacaaaa tacaacttta tttttaatta cattggcttt
     6481 tatcccattt tatgttctta cagtttggtt ttttatgaag ccatatgaat ccatcaacaa
     6541 tactgaaatg gaaaacaatg ctcagctgac ttcaaaaata gttgagacac ttaacggtat
     6601 tgaaacaatt aaagcatata atgctgaata tatgatgtca tatgagacag aaaagagatt
     6661 tgtgaaatat ttgcgctctg cttttaagca tggagttatc gataatcttc aaaattctat
     6721 taaaatgttt ttggatttag caagtggagc attcatattg tggattggtt caactcaagt
     6781 gatgaaagga actctttcaa taggtcagct cattacatac aatgcattgt taacatattt
     6841 tttgaatcct ttacagaaca taataggcct tcaatcgaaa ctccagtcag cttctgttgc
     6901 ttctaaacga ctgggagaaa tactagaagt agaacacgaa ataaaagata aggatgctca
     6961 aataacaacg ccagggtcta ttaatggccc aattgaattt attaaaatta actttcgata
     7021 tggtactcgg cgactaatcc taaaagatat tacactacgt atagataaag gggagaaagt
     7081 cgcttttatt ggagagagcg gttccggaaa atctactcta actaagctct taatgaaatt
     7141 ttatacagct gagtctggtg atattttaat taatggttat catatcaatg atattcatgc
     7201 tcattcatta agagaaagta taagttatat ccctcaagaa tctcacttta tacagggttc
     7261 catttttgaa aaccttctgc tcggtaactc aggcagtttt acctttgaag agattataga
     7321 agtatgcaaa caaacaaatg tacacgattt tgtcaatgat ttaccaatga gatacgatac
     7381 tctcgtagag gaaaacgggt ctaatttatc tggaggccag aagcaaagac tcgcaattgc
     7441 cagagcatta ttaagaaaac ctaacattct cataatggat gaatcaacaa gcaatctcga
     7501 tacgactacc gaacagggaa tatcaaaaat gatatacgat cagactgttg gtataactac
     7561 gattataatc gctcaccgtt tgagtacaat tatgaattgt gacaaaatat ttgtcatgga
     7621 aaatggagaa atcatagagt atgggaacca caatgattta ttgaagaaaa aaggcaagta
     7681 ctatgagttg tgggagaacc aaatgccatc cagagggatg gtgactattt agatgaaacg
     7741 taactttttc aatttacatg atttgaagga tagcagagaa ttctatgaat caaaacccaa
     7801 accaattggt gttttcttta catatatact gatagcttta cttattgcat gtattgtttt
     7861 tagtttctat ggaaagaaag aagtgattct aaaaacgaca gctgacatcc aatatacaaa
     7921 gcctaacagc aacgtaacaa acgaagtagc cggcaaagta aaaacagttg acattaaaca
     7981 ggttgataag gtgaaaaagg gagatactct attaactcta gacaatacgg aaatccaagc
     8041 gcagaaaaga gctgttaaag cagatatcaa agatttaaaa gaacaagctg cgttaaacaa
     8101 aactctaaaa aaaagtattg aaaatgacaa aaatttattc agtgaggacg atcattgggg
     8161 ttatcaagat caatatctct cgtacgaaaa acaaagtatt ttgttagagt catcaaaaga
     8221 aaatgcaaaa actcagcaga aaaaacttaa gaagcagaaa gaaagcataa aagatagtct
     8281 ggataagaca aaaaacaaag tcaaactaaa gcttcaaaga atttctgatc tgcaagactc
     8341 cattaaaaac aataaatcct ttgccaaaca ggatgataag tacagttctt actataatag
     8401 ttatcaaact aacaaacaaa atgtagagca gcagcttgat gatctacgga agatgaaaga
     8461 tgagctcgat aaaaaccgtt tttcacagca gaaagagaac ttgaacggac agcttgaaag
     8521 tttaaaacaa gatatgttag taaaactaag tgaagaaaaa gacgaattaa atcaatctct
     8581 tgatgagatt aacagttcaa ttaaaagtga cgattctgac agtgattccg ataactcaga
     8641 ggaaacaaat tataagcttt ctattgaaca gctcaaaaca aacttgctaa atcagacatc
     8701 tcaaaagcaa acagatcttc agaccactct taaatcaaaa gaggatgatc taaagatgat
     8761 agatttacaa ttagaaaaat ataaaataaa agcagcaagt gacggctatg ttaatgtact
     8821 aacaaatata tctccaggtg acaatttaca agcaggcact gctattttga ctattatccc
     8881 tgataaagag aagcttaaag ctaatattta tattccgagt catgagatca caaatattaa
     8941 tgaaaaagat gaagtaagat tccatattga aaatacaaat caaaccatca aaggtgtcat
     9001 tacaaaaata agtccagaca gtattagtga tcaaaacgga caaaaatttt atattgctga
     9061 aagcacaata gagaaaaata aagttatgaa cgataacgga tcaactttac acttaaaaaa
     9121 tggaatgcag accgatgtat caattatagt ggattctaaa aggtacattg attatctact
     9181 agaaatacta catttacaat aatataataa atataaatcc aacagaggca atctgtttat
     9241 gggttactca ccggtctgaa ataatgtact tagaataagt gaaccactca aaataaacta
     9301 ttatgcaatt tcatttttgt ggatttattt cttgttttat gtaattatgc tataattaca
     9361 actaaatttt caacagaaag gtcaagcaat ttatgtcgca aaacaaacta ttatttttac
     9421 tcttttcatt ttcttctatt attcacttgc tcttcaatac gattttagat cctacttcaa
     9481 gctggaaatc ttggtcggtg aacattgcgc taattctttt agcccttcta tttttaaatt
     9541 tcactttgaa agaaaagaaa gaaactcaca agaccaagtg acataacgac acaaagcccg
     9601 gactgactat ccgggcaaat ttatatcctg taaacgttac ctctcttagg ttttcttttc
     9661 ataacatact gaagttactc tccggccttc catttcagcc actggctggt ttctctcgtt
     9721 tatagcaata caaccttata cttcttcaca tccaaaaact gcaaaaactt cctcgccagc
     9781 acttccggcg catgcgcctt cccttcatcg agtcgataca atatcagccc gataatcatc
     9841 gccgatacat aataggcata aagctttttc tccgcaggaa tattagtttg ctgatgcaga
     9901 taaaatgatt ccaacgcttt gagcaactcg ggtatcacat gaggaacaac ccagtcccga
     9961 ttgagcaaat ggacaatagg catgcggtct aaagcagaaa gcaggccggc gagcacctcc
    10021 tccgcttctt cgaaggaaag ctcattcgga cttgaggcaa tcgtcaggtg atcaatgatc
    10081 tccgcacatg atcgctgtat catggtttgg agcaattcct ctttattggc atagtgatca
    10141 taaaaagttg cgcggcggat attgctttta cgcgtaatat ccgaaatcgt gatgcccgcg
    10201 tagtcttgtt tctccgccaa tacgtccaga aatgcctgct ggagcgcctc tctcgttcga
    10261 accacccgcc tgtcgattgg cttgcccttc tctcgctctc ctggcacagc ttgtccaaac
    10321 agccaataaa atctcttttg agaaacaagc tcccatacct tttggctgat agcttccgga
    10381 gccgcggccg catcctcatt cagccaatac aggataattg cgtatgtgta caaggcccgg
    10441 taatgtccgt aaatttctcg ttcgatcggc gtcaaattca catggaccgg agtcagcagc
    10501 acatcctgct gaaacacatc cctaaaaaaa cgatggaaat gccctctgtt catcatcaca
    10561 gaaaaaaagg atcgatgctc atgaacaaag gacagcgtcg gatgcaccgt ttgccgtttt
    10621 ttgttcaaat gaagggtatc catatgactg aaggcgtcaa aaagcgcttt gcccagtcct
    10681 tccttcatgt cttcgatcac atcctcaatg attgaaaact tatcctcata ataaaggtag
    10741 agcgtcccac ggctcacttt ggccctttca gcgatttctt tcattgtgat atgttgcata
    10801 tctctttctt ccaataaagc cagcagcgcc tgtttcactt gagcttcggc agattccggc
    10861 acaaaagaca cctccaatca ttagacagtt gttcaatata tgtacggtaa cgtatagatg
    10921 gttcaccgtt gtctttctta taaaaaaggt accaccttat aataggtccg agaaaagaag
    10981 aaagcaaatg agggggatct tacaatggaa cagaaagtaa aggacgacat ccagcgtgtc
    11041 tttcagcttc agaaaaaaca gcaaaaagcc ttgcgtgctt caacagcgga acagcgcaaa
    11101 gagaagcttc agcgcttttt agattccgtc atcgcccatg aggaagaaat cattgaagcg
    11161 atccgcaaag acgtccgcaa accatatcac gaggtcaaaa aagcggaaat cgaaggaacg
    11221 aaaaaagcga tcagagataa tatgaacaac ctggaacaat ggatggcgcc taaggaagtc
    11281 ggttcatcgt taagccctga ggcaaacggg attcttatgt acgagcctaa aggcgtcaca
    11341 ctcatcctcg gcccgtggaa ctatccgttt atgctgacga tggcgccgct tgccgcttct
    11401 ctcgcagccg gaaacagcgc gattgtgaag ctgtccgatt tcacgatgaa cacaagcaac
    11461 attgccgcta aagtgataag agacgcgttt gatgaaaaag aagtcgcgat ttttgaagga
    11521 gaggttgagg tggcaaccga gcttcttgat cagccgtttg accatatttt cttcactgga
    11581 agcacaaatg tcgggaaaat cgtcatgaca gcggcggcca aacacttggc atctgtcaca
    11641 cttgagcttg gcggcaaaag cccaacgatt atcgacagcg aatacgatct catggacgca
    11701 gcgaaaaaaa tcgccgtcgg caaattcgta aacgccggcc aaacctgcat cgcacctgat
    11761 tacctgttca ttaaaaaaga cgttcaggac aggttcgcgg gcattttaca aacaattgtc
    11821 aacgcaggat ttatggagga tgatcacacc ccagaccgca gcaaatttac gcaaatcgtc
    11881 aatgaccgca acttcaaccg cgtcaaagac ctgttcgacg atgccatcga aaaaggggcg
    11941 gaagtggtgt tcggcggcgt atttgatgcc agtgaccgca cgatctcgcc aaccgttttg
    12001 aaaaacgtca cgcctgatat gaaaatcatg caggaggaaa tcttcgcacc gatcctgcca
    12061 atgatgaatt atgaagacat cgacgaggtc atcgattacg taaatgatcg cgataaaccg
    12121 cttgcgcttt atgtgttcag caaaaaccaa gacctgattg acaacgtcct tcagcacacg
    12181 acatcaggaa atgccgccat caatgatgtc gtcgtccatt tcagtgacgt caacctgcca
    12241 ttcggcggcg taaacacaag cggaatcggc tcctatcatg gggtatacgg attcaaagag
    12301 ttttctcatg agaagggtgt atttattcaa gcctccaaat aatcgtaacg aagagaatct
    12361 gcatcatctt gcaggttctt tttttatctt tatatcacct aaataaagag attaaaagtg
    12421 ataaaatacc atttttacta cgagaccaaa ccctgcagcc tctaacgtat aatatcccag
    12481 aaaacttcaa aggagtaaaa tgatacatgg aaaaaccagc aggattttgg attcgggcag
    12541 ccgcctctat tattgatgta tttattatag ctatattctc tttcattatg attttcatta
    12601 acaccttcat tgtgttgcca ctcattgatg cggcaggtac acacatgtca gaagcccaat
    12661 atgagttttt catgttgatc attggaacaa tccctgtttt ggccatcata tttattttcg
    12721 ctattcttta ct
//
