GCA_013266935.1 - 18 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

JABRVH010000010 (original name was: JABRVH010000010.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	NRPS,transAT-PKS,T3PKS,PKS-like	57,174	162,410	bacillaene	Polyketide + NRP	100%

JABRVH010000018 (original name was: JABRVH010000018.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 10.1	sactipeptide	162,020	183,410	subtilosin A	RiPP:Thiopeptide	100%

JABRVH010000002 (original name was: JABRVH010000002.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 12.1	NRPS	1	3,106

JABRVH010000020 (original name was: JABRVH010000020.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 13.1	terpene	52,748	73,551

JABRVH010000021 (original name was: JABRVH010000021.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 14.1	NRPS	1	9,882	surfactin	NRP:Lipopeptide	8%

JABRVH010000022 (original name was: JABRVH010000022.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 15.1	NRPS	112,345	140,349	surfactin	NRP:Lipopeptide	43%

JABRVH010000024 (original name was: JABRVH010000024.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 17.1	NRPS	4,397	51,533	bacillibactin	NRP	100%

JABRVH010000025 (original name was: JABRVH010000025.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 18.1	terpene	9,713	31,611

JABRVH010000003 (original name was: JABRVH010000003.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 23.1	NRPS	1	23,943	fengycin	NRP	26%

JABRVH010000037 (original name was: JABRVH010000037.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 31.1	RiPP-like	54,717	59,907

JABRVH010000038 (original name was: JABRVH010000038.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 32.1	T3PKS	77,144	112,496

JABRVH010000004 (original name was: JABRVH010000004.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 34.1	NRPS	1	21,341	surfactin	NRP:Lipopeptide	39%

JABRVH010000040 (original name was: JABRVH010000040.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 35.1	other	2,921	27,885	bacilysin	Other	100%

JABRVH010000050 (original name was: JABRVH010000050.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 46.1	NRPS,betalactone	1,859	30,152	fengycin	NRP	80%

JABRVH010000054 (original name was: JABRVH010000054.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 50.1	RiPP-like	1	7,661

JABRVH010000008 (original name was: JABRVH010000008.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 73.1	CDPS	62,009	82,755

JABRVH010000083 (original name was: JABRVH010000083.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 74.1	RRE-containing	1	1,081

JABRVH010000090 (original name was: JABRVH010000090.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 76.1	NRPS	1	3,212

No secondary metabolite regions were found in these records:: JABRVH010000001 (original name was: JABRVH010000001.1); JABRVH010000011 (original name was: JABRVH010000011.1); JABRVH010000012 (original name was: JABRVH010000012.1); JABRVH010000013 (original name was: JABRVH010000013.1); JABRVH010000014 (original name was: JABRVH010000014.1); JABRVH010000015 (original name was: JABRVH010000015.1); JABRVH010000016 (original name was: JABRVH010000016.1); JABRVH010000017 (original name was: JABRVH010000017.1); JABRVH010000019 (original name was: JABRVH010000019.1); JABRVH010000023 (original name was: JABRVH010000023.1); JABRVH010000026 (original name was: JABRVH010000026.1); JABRVH010000027 (original name was: JABRVH010000027.1); JABRVH010000028 (original name was: JABRVH010000028.1); JABRVH010000029 (original name was: JABRVH010000029.1); JABRVH010000030 (original name was: JABRVH010000030.1); JABRVH010000031 (original name was: JABRVH010000031.1); JABRVH010000032 (original name was: JABRVH010000032.1); JABRVH010000033 (original name was: JABRVH010000033.1); JABRVH010000034 (original name was: JABRVH010000034.1); JABRVH010000035 (original name was: JABRVH010000035.1); JABRVH010000036 (original name was: JABRVH010000036.1); JABRVH010000039 (original name was: JABRVH010000039.1); JABRVH010000041 (original name was: JABRVH010000041.1); JABRVH010000042 (original name was: JABRVH010000042.1); JABRVH010000043 (original name was: JABRVH010000043.1); JABRVH010000044 (original name was: JABRVH010000044.1); JABRVH010000045 (original name was: JABRVH010000045.1); JABRVH010000046 (original name was: JABRVH010000046.1); JABRVH010000047 (original name was: JABRVH010000047.1); JABRVH010000048 (original name was: JABRVH010000048.1); JABRVH010000049 (original name was: JABRVH010000049.1); JABRVH010000005 (original name was: JABRVH010000005.1); JABRVH010000051 (original name was: JABRVH010000051.1); JABRVH010000052 (original name was: JABRVH010000052.1); JABRVH010000053 (original name was: JABRVH010000053.1); JABRVH010000055 (original name was: JABRVH010000055.1); JABRVH010000056 (original name was: JABRVH010000056.1); JABRVH010000057 (original name was: JABRVH010000057.1); JABRVH010000058 (original name was: JABRVH010000058.1); JABRVH010000059 (original name was: JABRVH010000059.1); JABRVH010000006 (original name was: JABRVH010000006.1); JABRVH010000060 (original name was: JABRVH010000060.1); JABRVH010000061 (original name was: JABRVH010000061.1); JABRVH010000062 (original name was: JABRVH010000062.1); JABRVH010000064 (original name was: JABRVH010000064.1); JABRVH010000065 (original name was: JABRVH010000065.1); JABRVH010000066 (original name was: JABRVH010000066.1); JABRVH010000067 (original name was: JABRVH010000067.1); JABRVH010000068 (original name was: JABRVH010000068.1); JABRVH010000069 (original name was: JABRVH010000069.1); JABRVH010000007 (original name was: JABRVH010000007.1); JABRVH010000071 (original name was: JABRVH010000071.1); JABRVH010000072 (original name was: JABRVH010000072.1); JABRVH010000074 (original name was: JABRVH010000074.1); JABRVH010000075 (original name was: JABRVH010000075.1); JABRVH010000076 (original name was: JABRVH010000076.1); JABRVH010000077 (original name was: JABRVH010000077.1); JABRVH010000009 (original name was: JABRVH010000009.1)

Compact view

c00002_JABRVH0.. - Region 1 - NRPS,PKS-like,T3PKS,transAT-PKS

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Location: 57,174 - 162,410 nt. (total: 105,237 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)
PKS-like: (t2pks2 or ksIII)

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core biosynthetic genes

additional biosynthetic genes

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 57173 - 162410:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - ccmal - ohmal - mal) + (ccmal - mal - ohmal - mal - mal) + (ccmal - ohmal - mal - mal) + (X - ccmal - ccmal - ccmal) + (mal - mal - ccmal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 71812 - 162410:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - ccmal - ohmal - mal) + (ccmal - mal - ohmal - mal - mal) + (ccmal - ohmal - mal - mal) + (X - ccmal - ccmal - ccmal) + (mal - mal - ccmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg2_80

Search NORINE for peptide: strict or relaxed

AMP-binding (497..905): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVsnmAiIYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 60% (weak)

ctg2_83

Search NORINE for peptide: strict or relaxed

CAL_domain (60..471): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 10.9
NH2: 10.3
shikimic_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

AMP-binding (1159..1554): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGMIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

ctg2_89

PKS_AT (4..288): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 66.7%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 95.0
inactive: 41.2
Methoxymalonyl-CoA: 29.1
Methylmalonyl-CoA: 22.1
Propionyl-CoA: 16.3
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg2_90

PKS_AT (7..293): pk

ATSignature: (unknown)

No matches above 50%

minowa: inactive

Prediction, score:

inactive: 30.0
Malonyl-CoA: 23.0
Benzoyl-CoA: 8.8
Isobutyryl-CoA: 8.4
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg2_92

PKS_AT (4..284): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 96.7
Methoxymalonyl-CoA: 50.0
inactive: 35.3
Methylmalonyl-CoA: 31.5
Propionyl-CoA: 22.2
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

c00010_JABRVH0.. - Region 1 - sactipeptide

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Location: 162,020 - 183,410 nt. (total: 21,391 nt) Show pHMM detection rules used

Region on contig edge.

sactipeptide: (subtilosin or thuricin or TIGR04404 or Subtilosin_A or skfc)

Legend:

core biosynthetic genes

additional biosynthetic genes

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KnownClusterBlast

Sactipeptides

Similar known gene clusters

Sactipeptide predictions

Putative Sactipeptide(s)

ctg10_174 leader / core peptide: MKKAVIVENK - GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

Sactipeptides

Core peptide predictions

ctg10_174: Putative sactipeptide; RODEO score: 33.0; Core sequence, approximate: GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

c00012_JABRVH0.. - Region 1 - NRPS

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Location: 1 - 3,106 nt. (total: 3,106 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

No matches found.

c00013_JABRVH0.. - Region 1 - terpene

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Location: 52,748 - 73,551 nt. (total: 20,804 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

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resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

c00014_JABRVH0.. - Region 1 - NRPS

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Location: 1 - 9,882 nt. (total: 9,882 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 9882:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (val - asp)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg14_1

Search NORINE for peptide: strict or relaxed

AMP-binding (470..864): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWIGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 100% (strong)

AMP-binding (1501..1904): asp

NRPSPredictor2: asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGHIGK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 100% (strong)

c00015_JABRVH0.. - Region 1 - NRPS

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Location: 112,345 - 140,349 nt. (total: 28,005 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 112344 - 140349:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (glu - leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg15_129

Search NORINE for peptide: strict or relaxed

AMP-binding (466..867): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAKDLGVVDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 100% (strong)

AMP-binding (1510..1908): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAFMMGMVFK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

c00017_JABRVH0.. - Region 1 - NRPS

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Location: 4,397 - 51,533 nt. (total: 47,137 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 4396 - 51533:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg17_25

Search NORINE for peptide: strict or relaxed

AMP-binding (463..861): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

AMP-binding (1519..1935): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

ctg17_27

Search NORINE for peptide: strict or relaxed

AMP-binding (31..435): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

c00018_JABRVH0.. - Region 1 - terpene

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Location: 9,713 - 31,611 nt. (total: 21,899 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

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KnownClusterBlast

Similar known gene clusters

No matches found.

c00023_JABRVH0.. - Region 1 - NRPS

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Location: 1 - 23,943 nt. (total: 23,943 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 23943:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-orn) + (tyr - D-thr) + (glu - D-val) + (pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg23_1

Search NORINE for peptide: strict or relaxed

AMP-binding (413..818): orn

NRPSPredictor2: orn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: orn, horn
Single AA prediction:: orn

Stachelhaus prediction details:

Stachelhaus sequence:: DVGEIGSIDK
Nearest Stachelhaus code:: orn
Stachelhaus code match:: 100% (strong)

ctg23_2

Search NORINE for peptide: strict or relaxed

AMP-binding (477..868): tyr

NRPSPredictor2: tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: tyr, bht
Single AA prediction:: tyr

Stachelhaus prediction details:

Stachelhaus sequence:: DGTITAEVAK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 100% (strong)

AMP-binding (1509..1907): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

ctg23_3

Search NORINE for peptide: strict or relaxed

AMP-binding (469..870): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: glu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWHFGGVDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 100% (strong)

AMP-binding (1510..1903): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DVFWIGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 100% (strong)

ctg23_4

Search NORINE for peptide: strict or relaxed

AMP-binding (470..867): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAHVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 100% (strong)

c00031_JABRVH0.. - Region 1 - RiPP-like

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Location: 54,717 - 59,907 nt. (total: 5,191 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

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Gene details

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KnownClusterBlast

Similar known gene clusters

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c00032_JABRVH0.. - Region 1 - T3PKS

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Location: 77,144 - 112,496 nt. (total: 35,353 nt) Show pHMM detection rules used

Region on contig edge.

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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core biosynthetic genes

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KnownClusterBlast

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c00034_JABRVH0.. - Region 1 - NRPS

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Location: 1 - 21,341 nt. (total: 21,341 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 21341:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg34_22

Search NORINE for peptide: strict or relaxed

AMP-binding (205..603): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGCVFK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

c00035_JABRVH0.. - Region 1 - other

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Location: 2,921 - 27,885 nt. (total: 24,965 nt) Show pHMM detection rules used

Region on contig edge.

other: (LmbU or Neocarzinostat or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)

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core biosynthetic genes

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c00046_JABRVH0.. - Region 1 - NRPS,betalactone

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Location: 1,859 - 30,152 nt. (total: 28,294 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
betalactone: (HMGL-like and AMP-binding)

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core biosynthetic genes

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 1858 - 30152:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ile)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg46_15

Search NORINE for peptide: strict or relaxed

AMP-binding (13..445): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: N/A
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: gclhIAApvK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 40% (weak)

ctg46_20

Search NORINE for peptide: strict or relaxed

AMP-binding (459..852): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFYGITFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 100% (strong)

c00050_JABRVH0.. - Region 1 - RiPP-like

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Location: 1 - 7,661 nt. (total: 7,661 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

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KnownClusterBlast

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c00073_JABRVH0.. - Region 1 - CDPS

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Location: 62,009 - 82,755 nt. (total: 20,747 nt) Show pHMM detection rules used

CDPS: (CDPS or cycdipepsynth)

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c00074_JABRVH0.. - Region 1 - RRE-containing

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Location: 1 - 1,081 nt. (total: 1,081 nt) Show pHMM detection rules used

Region on contig edge.

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

Legend:

core biosynthetic genes

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KnownClusterBlast

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c00076_JABRVH0.. - Region 1 - NRPS

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Location: 1 - 3,212 nt. (total: 3,212 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 3212:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg76_1

Search NORINE for peptide: strict or relaxed

AMP-binding (186..583): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAHVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 100% (strong)