LOCUS       c00076_JABRVH0..        3212 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JABRVH010000090.1 Bacillus subtilis strain CRN 16 S16_contig_90,
            whole genome shotgun sequence.
ACCESSION   JABRVH010000090
VERSION     JABRVH010000090
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-21 00:06:22
            Original ID  :: JABRVH010000090.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3212
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3212
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:3212](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..3212
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..3212
                     /SMILES="N1C(CCC1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3212
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS_motif       3..62
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg76_1_0001"
                     /evalue="3.00E-10"
                     /label="C5_DCL_263-294"
                     /locus_tag="ctg76_1"
                     /protein_end="20"
                     /protein_start="0"
                     /score="32.6"
                     /tool="antismash"
                     /translation="AEIEGIEHMVGLFINTMPVR"
     CDS             3..3212
                     /NRPS_PKS="Domain: AMP-binding (186-583). E-value:
                     1.6e-105. Score: 344.8. Matches aSDomain:
                     nrpspksdomains_ctg76_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (689-758). E-value: 1.3e-24. Score:
                     78.0. Matches aSDomain: nrpspksdomains_ctg76_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (773-1051). E-value:
                     1.9e-104. Score: 340.6. Matches aSDomain:
                     nrpspksdomains_ctg76_1_Condensation_LCL.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     326.1; E-value: 5.1e-99)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_1"
                     /sec_met_domain="Condensation (E-value: 7.7e-89, bitscore:
                     283.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.4e-114, bitscore:
                     367.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.1e-17, bitscore:
                     49.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="AEIEGIEHMVGLFINTMPVRVQGAKTPFLQLIKDMQKDRLAAEAY
                     SYHPLYEIQSRSAVKQGLIDHILVFENYPVQQEIQMLNKQEHASDLFQIHNFTVADETN
                     YSFYLMVAPGEEIHIKMNYDAEQHDRSFVLSVKEHLLNAVSQILNNPNLPPEEIDITTD
                     TEKRQLIGEITDRTPVYETIHAMFEKQAEKTPDAHAVIDQACSLTYRELNKAANRLARH
                     LRMKGVVRQEPVAIMMERSAAFITGVLGILKAGGAIVPVDPHYPADRIRYILHDCGCSH
                     VVSQAHLSSSLEDNYIITHPEDIESKVDGSNIKSVNNADDLLYMIYTSGTTGKPKGVQF
                     EHRNMANLLKFEYTHSGIDFEADVLQFATPSFDVCYQEIFSALLKGGTLHIVPEAIKRD
                     VPQLFAFINKHQTNIVFLPTAFIKMIFSERELANSFPDGVKHLIAAGEQLMISDLFQDV
                     LRERGIHLHNHYGPSETHVVSTYTIHPGDPIPELPPIGKPIGCTDLYILNHQKQLQPCG
                     VPGELYISGASVARGYVNHDKLTSDKFSSDPFKPGVIMYRTGDLARRLEDGNIEYIGRA
                     DNQVKIRGYRIEPQEIEVTLMNHPDISEAAILIWQDQNGEHELCAYYCSVQKLNAIDLR
                     SYMASELPEYMIPAKWIWVDSIPLTPNGKVDRAALPGPDASISGNPYTAPRNLLEAKLS
                     QLFEDVLNNGHIGIQDNFFDHGGHSLKATVLMSRIAKEFHVQVSLKDIFAHPTVEGLAS
                     IIREAEQNPYAAIEPAEERGTYPVSSAQKRMYVLQQLDEGVAYNMPAVLELEGALDVAK
                     LSAVCKELINRHEPLRTSFVSGADDEPVQRIHTEVPFTLSKETTIEGFVRPFDLSQAPL
                     FRAGLIEVSNEKHVLLVDMHHIISDGVSVQLLIREFTDLYANRQLKPLRIQYKDYAVWQ
                     QKFKKGDSYQKQETYWQQQFSGDLPILELPTDKRRPAERQFIGGKVTFQLDKEITARIK
                     RLAHKNRSTLYMTLLALYSAFLSRLSGQDDIVIGSPIAGRPHADLEAVLGMFVNTLALR
                     TRPAGNKTFEEFLKEVRQTALE"
     CDS_motif       108..224
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg76_1_0002"
                     /evalue="9.60E-21"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="ctg76_1"
                     /protein_end="74"
                     /protein_start="35"
                     /score="66.3"
                     /tool="antismash"
                     /translation="QKDRLAAEAYSYHPLYEIQSRSAVKQGLIDHILVFENYP"
     aSDomain        561..1751
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg76_1_AMP-binding.1"
                     /evalue="1.60E-105"
                     /label="ctg76_1_AMP-binding.1"
                     /locus_tag="ctg76_1"
                     /protein_end="583"
                     /protein_start="186"
                     /score="344.8"
                     /specificity="consensus: pro"
                     /tool="antismash"
                     /translation="FEKQAEKTPDAHAVIDQACSLTYRELNKAANRLARHLRMKGVVRQ
                     EPVAIMMERSAAFITGVLGILKAGGAIVPVDPHYPADRIRYILHDCGCSHVVSQAHLSS
                     SLEDNYIITHPEDIESKVDGSNIKSVNNADDLLYMIYTSGTTGKPKGVQFEHRNMANLL
                     KFEYTHSGIDFEADVLQFATPSFDVCYQEIFSALLKGGTLHIVPEAIKRDVPQLFAFIN
                     KHQTNIVFLPTAFIKMIFSERELANSFPDGVKHLIAAGEQLMISDLFQDVLRERGIHLH
                     NHYGPSETHVVSTYTIHPGDPIPELPPIGKPIGCTDLYILNHQKQLQPCGVPGELYISG
                     ASVARGYVNHDKLTSDKFSSDPFKPGVIMYRTGDLARRLEDGNIEYIGRADNQVKIR"
     aSModule        561..2276
                     /complete
                     /domains="nrpspksdomains_ctg76_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg76_1_PCP.1"
                     /locus_tags="ctg76_1"
                     /monomer_pairings="pro -> pro"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       747..788
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg76_1_0003"
                     /evalue="2.70E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg76_1"
                     /protein_end="262"
                     /protein_start="248"
                     /score="14.3"
                     /tool="antismash"
                     /translation="LGILKAGGAIVPVD"
     CDS_motif       972..1028
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg76_1_0004"
                     /evalue="7.00E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg76_1"
                     /protein_end="342"
                     /protein_start="323"
                     /score="27.8"
                     /tool="antismash"
                     /translation="YMIYTSGTTGKPKGVQFEH"
     CDS_motif       1545..1634
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg76_1_0005"
                     /evalue="3.40E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg76_1"
                     /protein_end="544"
                     /protein_start="514"
                     /score="41.8"
                     /tool="antismash"
                     /translation="PCGVPGELYISGASVARGYVNHDKLTSDKF"
     CDS_motif       1716..1781
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg76_1_0006"
                     /evalue="3.30E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg76_1"
                     /protein_end="593"
                     /protein_start="571"
                     /score="38.3"
                     /tool="antismash"
                     /translation="YIGRADNQVKIRGYRIEPQEIE"
     aSDomain        2070..2276
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg76_1_PCP.1"
                     /evalue="1.30E-24"
                     /label="ctg76_1_PCP.1"
                     /locus_tag="ctg76_1"
                     /protein_end="758"
                     /protein_start="689"
                     /score="78.0"
                     /tool="antismash"
                     /translation="EAKLSQLFEDVLNNGHIGIQDNFFDHGGHSLKATVLMSRIAKEFH
                     VQVSLKDIFAHPTVEGLASIIREA"
     aSDomain        2322..3155
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg76_1_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="1.90E-104"
                     /label="ctg76_1_Condensation_LCL.1"
                     /locus_tag="ctg76_1"
                     /protein_end="1051"
                     /protein_start="773"
                     /score="340.6"
                     /tool="antismash"
                     /translation="TYPVSSAQKRMYVLQQLDEGVAYNMPAVLELEGALDVAKLSAVCK
                     ELINRHEPLRTSFVSGADDEPVQRIHTEVPFTLSKETTIEGFVRPFDLSQAPLFRAGLI
                     EVSNEKHVLLVDMHHIISDGVSVQLLIREFTDLYANRQLKPLRIQYKDYAVWQQKFKKG
                     DSYQKQETYWQQQFSGDLPILELPTDKRRPAERQFIGGKVTFQLDKEITARIKRLAHKN
                     RSTLYMTLLALYSAFLSRLSGQDDIVIGSPIAGRPHADLEAVLGMFVNTLALRTRP"
     aSModule        2322..3155
                     /domains="nrpspksdomains_ctg76_1_Condensation_LCL.1"
                     /incomplete
                     /locus_tags="ctg76_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2385..2498
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg76_1_0007"
                     /evalue="2.00E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg76_1"
                     /protein_end="832"
                     /protein_start="794"
                     /score="49.2"
                     /tool="antismash"
                     /translation="AYNMPAVLELEGALDVAKLSAVCKELINRHEPLRTSFV"
     CDS_motif       2670..2735
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg76_1_0008"
                     /evalue="9.10E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg76_1"
                     /protein_end="911"
                     /protein_start="889"
                     /score="31.0"
                     /tool="antismash"
                     /translation="MHHIISDGVSVQLLIREFTDLY"
     CDS_motif       3057..3146
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg76_1_0009"
                     /evalue="1.30E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg76_1"
                     /protein_end="1048"
                     /protein_start="1018"
                     /score="52.8"
                     /tool="antismash"
                     /translation="DIVIGSPIAGRPHADLEAVLGMFVNTLALR"
ORIGIN
        1 ccgcagaaat cgaaggcatt gaacatatgg taggtctttt cattaatacg atgccggttc
       61 gggtgcaggg ggcaaaaacg ccttttcttc aacttataaa agatatgcaa aaagaccgtc
      121 ttgccgctga agcgtacagc taccatcctt tatatgagat tcaatcccgc tcagctgtta
      181 aacaagggct gattgatcat attctcgtat ttgaaaacta tccggtgcag caagagattc
      241 aaatgctgaa caaacaggaa catgcttctg atctttttca gattcataat ttcactgtcg
      301 cagatgaaac caactacagc ttttatctta tggtggcgcc aggggaagaa attcatatca
      361 aaatgaacta tgatgcggag cagcacgatc ggtcttttgt gctctctgtc aaagagcatc
      421 ttctgaatgc tgtatcgcaa atcttaaata atccgaatct tccacctgaa gaaatcgata
      481 tcacgacaga tactgaaaag cggcagctga ttggagaaat cacagatcga acaccagttt
      541 acgaaaccat ccatgccatg tttgaaaagc aagcggaaaa gacaccagat gctcatgctg
      601 taattgatca agcctgctca ttaacataca gagaactgaa taaagcggct aacagattgg
      661 cacggcattt acgaatgaaa ggcgttgtga gacaggaacc cgttgcgatt atgatggaac
      721 gctctgcggc gtttatcacc ggcgttcttg gaatcttaaa ggcaggcggc gccattgttc
      781 cggttgatcc gcattacccg gctgacagaa tccgttatat tctgcatgat tgcggctgtt
      841 cgcatgttgt ttcacaagcg cacctttcct catcgttaga agacaattac attatcactc
      901 atccagaaga tatcgaaagc aaagtagacg gcagtaacat aaagtcagtc aacaatgctg
      961 acgatctgct gtatatgatt tatacatcag gcacaacagg taaaccaaag ggtgttcaat
     1021 ttgagcatcg aaacatggct aacttgctga agttcgaata tactcactcc ggcattgact
     1081 ttgaagcaga tgttctgcaa tttgctacac cttccttcga cgtctgctat caagaaatat
     1141 tttctgcgct tctgaaaggc ggcacactcc acatcgtgcc agaagccata aaaagagatg
     1201 tgcctcagct gtttgcattt ataaacaagc atcagacgaa tattgtgttt ctcccaactg
     1261 cttttatcaa aatgattttc agcgagcgag aacttgcgaa ctcgtttcct gatggcgtca
     1321 aacacctgat cgcagccggg gaacaattaa tgatttcaga ccttttccaa gatgtgttgc
     1381 gtgaacgcgg catacacctg cacaatcatt acggaccttc agaaactcat gtggtatcta
     1441 cgtataccat tcatcctgga gaccctattc ctgagcttcc gccaatcggt aaaccgatag
     1501 gctgtactga tctatatatt ttgaatcatc aaaaacagct tcagccatgc ggcgtaccag
     1561 gcgaactcta tatttccggc gcaagtgttg ccagaggata tgtcaatcac gataaactga
     1621 caagcgacaa attttcatcc gatccattca agcctggtgt gatcatgtac cggacaggtg
     1681 atttggccag acggcttgaa gacggcaaca tcgaatatat cggacgggca gacaatcaag
     1741 tgaaaatcag aggttatcga attgagccgc aagaaatcga agtcacgtta atgaatcacc
     1801 cggacattag tgaggctgcc attctcatct ggcaagatca aaacggtgaa catgaattat
     1861 gcgcttacta ttgcagtgta caaaagctga acgcaataga tttacgcagt tatatggcta
     1921 gtgagctccc agaatacatg attccggcga aatggatatg ggttgacagc atacctctta
     1981 ccccaaatgg aaaagtagat cgcgcagcac ttccggggcc agatgcttca atcagcggaa
     2041 acccatatac tgcccctcga aatctgttag aggcaaagct ttcacaacta tttgaagatg
     2101 tactgaataa tggccatata ggcatccaag acaacttttt tgaccatggc ggccactcgt
     2161 taaaagcaac agtgcttatg tcacggatcg caaaggaatt ccatgtgcaa gtttcgctta
     2221 aggacatctt tgctcatccg actgttgaag gattagcttc aatcattcga gaggcagaac
     2281 aaaatccgta tgcagcaatt gaaccagcag aagaaagggg tacatatcct gtatcttcgg
     2341 cccaaaaacg aatgtatgtg cttcaacagc ttgatgaggg tgtcgcctat aacatgcctg
     2401 cggtcttaga actggaaggt gcactggatg tcgccaaact gtctgctgta tgtaaagaac
     2461 tgatcaatcg gcatgagccg cttcgaactt cctttgtatc cggagctgat gacgagccgg
     2521 ttcagcgtat ccacaccgaa gtgccgttta cgttaagtaa agagaccact atcgagggat
     2581 ttgtccgtcc ctttgatctc agccaggcgc cattatttag agcaggcctt atagaagtgt
     2641 caaacgagaa gcatgtattg ctggtggata tgcaccatat catttcagat ggcgtatccg
     2701 ttcagctcct aatccgagaa tttaccgatc tttatgcaaa ccggcagctt aagccattgc
     2761 ggatccaata taaagattac gccgtatggc aacagaaatt taaaaaggga gactcgtacc
     2821 aaaagcagga gacttactgg cagcagcagt ttagcgggga ccttcctata ctggagcttc
     2881 caacagataa acgacgtccg gcagaacggc aattcatagg cggaaaagta acctttcaat
     2941 tggacaaaga gatcacggcc cgcataaagc ggctcgccca taaaaacaga agcacgcttt
     3001 atatgacgct tctcgctttg tattcagcct ttttgtctcg gttaagcggt caggatgata
     3061 tcgtgattgg ttcacctatc gccgggcggc cccatgccga ccttgaagct gttcttggga
     3121 tgttcgtcaa tacattggct ctccgcacac gcccggcggg taataagaca tttgaggaat
     3181 ttctaaaaga agtcagacag acggcactag aa
//
