GCA_013267025.1 - 15 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

JABRVC010000013 (original name was: JABRVC010000013.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 5.1	NRPS	1	3,979

JABRVC010000015 (original name was: JABRVC010000015.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 7.1	transAT-PKS,PKS-like,T3PKS,NRPS	206,141	313,264	bacillaene	Polyketide + NRP	100%

JABRVC010000019 (original name was: JABRVC010000019.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 11.1	NRPS	104,683	159,307	surfactin	NRP:Lipopeptide	82%

JABRVC010000022 (original name was: JABRVC010000022.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 15.1	NRPS	1	14,788	plipastatin	NRP	30%

JABRVC010000023 (original name was: JABRVC010000023.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 16.1	T3PKS	2,223	43,320

JABRVC010000028 (original name was: JABRVC010000028.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 21.1	CDPS	124,743	145,489

JABRVC010000032 (original name was: JABRVC010000032.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 26.1	terpene	1	14,195

JABRVC010000038 (original name was: JABRVC010000038.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 32.1	NRPS	1	9,994	plipastatin	NRP	15%

JABRVC010000039 (original name was: JABRVC010000039.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 33.1	NRPS	4,266	51,402	bacillibactin	NRP	100%

JABRVC010000043 (original name was: JABRVC010000043.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 38.1	NRPS,betalactone	1	27,659	fengycin	NRP	80%

JABRVC010000053 (original name was: JABRVC010000053.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 48.1	terpene	27,323	48,126

JABRVC010000071 (original name was: JABRVC010000071.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 67.1	NRPS	1	8,791	lichenysin	NRP	14%

JABRVC010000074 (original name was: JABRVC010000074.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 70.1	lanthipeptide-class-ii	1	9,720

JABRVC010000008 (original name was: JABRVC010000008.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 76.1	sactipeptide	1	11,896	subtilosin A	RiPP:Thiopeptide	100%
Region 76.2	other	14,637	39,661	bacilysin	Other	100%

Region	Type	From	To	Most similar known cluster	Similarity
Region 5.1	NRPS	1	3,979
Region 7.1	transAT-PKS,PKS-like,T3PKS,NRPS	206,141	313,264	bacillaene	Polyketide + NRP	100%
Region 11.1	NRPS	104,683	159,307	surfactin	NRP:Lipopeptide	82%
Region 15.1	NRPS	1	14,788	plipastatin	NRP	30%
Region 16.1	T3PKS	2,223	43,320
Region 21.1	CDPS	124,743	145,489
Region 26.1	terpene	1	14,195
Region 32.1	NRPS	1	9,994	plipastatin	NRP	15%
Region 33.1	NRPS	4,266	51,402	bacillibactin	NRP	100%
Region 38.1	NRPS,betalactone	1	27,659	fengycin	NRP	80%
Region 48.1	terpene	27,323	48,126
Region 67.1	NRPS	1	8,791	lichenysin	NRP	14%
Region 70.1	lanthipeptide-class-ii	1	9,720
Region 76.1	sactipeptide	1	11,896	subtilosin A	RiPP:Thiopeptide	100%
Region 76.2	other	14,637	39,661	bacilysin	Other	100%

No secondary metabolite regions were found in these records:: JABRVC010000001 (original name was: JABRVC010000001.1); JABRVC010000010 (original name was: JABRVC010000010.1); JABRVC010000011 (original name was: JABRVC010000011.1); JABRVC010000012 (original name was: JABRVC010000012.1); JABRVC010000014 (original name was: JABRVC010000014.1); JABRVC010000016 (original name was: JABRVC010000016.1); JABRVC010000017 (original name was: JABRVC010000017.1); JABRVC010000018 (original name was: JABRVC010000018.1); JABRVC010000002 (original name was: JABRVC010000002.1); JABRVC010000020 (original name was: JABRVC010000020.1); JABRVC010000021 (original name was: JABRVC010000021.1); JABRVC010000024 (original name was: JABRVC010000024.1); JABRVC010000025 (original name was: JABRVC010000025.1); JABRVC010000026 (original name was: JABRVC010000026.1); JABRVC010000027 (original name was: JABRVC010000027.1); JABRVC010000029 (original name was: JABRVC010000029.1); JABRVC010000003 (original name was: JABRVC010000003.1); JABRVC010000030 (original name was: JABRVC010000030.1); JABRVC010000031 (original name was: JABRVC010000031.1); JABRVC010000033 (original name was: JABRVC010000033.1); JABRVC010000034 (original name was: JABRVC010000034.1); JABRVC010000035 (original name was: JABRVC010000035.1); JABRVC010000036 (original name was: JABRVC010000036.1); JABRVC010000037 (original name was: JABRVC010000037.1); JABRVC010000004 (original name was: JABRVC010000004.1); JABRVC010000040 (original name was: JABRVC010000040.1); JABRVC010000041 (original name was: JABRVC010000041.1); JABRVC010000042 (original name was: JABRVC010000042.1); JABRVC010000044 (original name was: JABRVC010000044.1); JABRVC010000045 (original name was: JABRVC010000045.1); JABRVC010000046 (original name was: JABRVC010000046.1); JABRVC010000047 (original name was: JABRVC010000047.1); JABRVC010000048 (original name was: JABRVC010000048.1); JABRVC010000049 (original name was: JABRVC010000049.1); JABRVC010000005 (original name was: JABRVC010000005.1); JABRVC010000050 (original name was: JABRVC010000050.1); JABRVC010000051 (original name was: JABRVC010000051.1); JABRVC010000054 (original name was: JABRVC010000054.1); JABRVC010000055 (original name was: JABRVC010000055.1); JABRVC010000056 (original name was: JABRVC010000056.1); JABRVC010000057 (original name was: JABRVC010000057.1); JABRVC010000058 (original name was: JABRVC010000058.1); JABRVC010000059 (original name was: JABRVC010000059.1); JABRVC010000006 (original name was: JABRVC010000006.1); JABRVC010000060 (original name was: JABRVC010000060.1); JABRVC010000061 (original name was: JABRVC010000061.1); JABRVC010000062 (original name was: JABRVC010000062.1); JABRVC010000063 (original name was: JABRVC010000063.1); JABRVC010000064 (original name was: JABRVC010000064.1); JABRVC010000065 (original name was: JABRVC010000065.1); JABRVC010000067 (original name was: JABRVC010000067.1); JABRVC010000068 (original name was: JABRVC010000068.1); JABRVC010000069 (original name was: JABRVC010000069.1); JABRVC010000007 (original name was: JABRVC010000007.1); JABRVC010000070 (original name was: JABRVC010000070.1); JABRVC010000072 (original name was: JABRVC010000072.1); JABRVC010000073 (original name was: JABRVC010000073.1); JABRVC010000075 (original name was: JABRVC010000075.1); JABRVC010000076 (original name was: JABRVC010000076.1); JABRVC010000077 (original name was: JABRVC010000077.1); JABRVC010000078 (original name was: JABRVC010000078.1); JABRVC010000079 (original name was: JABRVC010000079.1); JABRVC010000080 (original name was: JABRVC010000080.1); JABRVC010000084 (original name was: JABRVC010000084.1); JABRVC010000086 (original name was: JABRVC010000086.1); JABRVC010000087 (original name was: JABRVC010000087.1); JABRVC010000088 (original name was: JABRVC010000088.1); JABRVC010000089 (original name was: JABRVC010000089.1); JABRVC010000009 (original name was: JABRVC010000009.1); JABRVC010000090 (original name was: JABRVC010000090.1)

Compact view

c00005_JABRVC0.. - Region 1 - NRPS

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Location: 1 - 3,979 nt. (total: 3,979 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 3979:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (glu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg5_1

Search NORINE for peptide: strict or relaxed

AMP-binding (463..864): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: glu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWHFGGVDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 100% (strong)

c00007_JABRVC0.. - Region 1 - NRPS,PKS-like,T3PKS,transAT-PKS

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Location: 206,141 - 313,264 nt. (total: 107,124 nt) Show pHMM detection rules used

transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))
PKS-like: (t2pks2 or ksIII)
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)
NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 206140 - 313264:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - ccmal - ohmal - mal) + (mal - ccmal - mal - ohmal - mal) + (mal - ccmal - ohmal - mal) + (X - ccmal - ccmal - ccmal) + (ccmal - mal - mal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 206140 - 296730:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - ccmal - ohmal - mal) + (mal - ccmal - mal - ohmal - mal) + (mal - ccmal - ohmal - mal) + (X - ccmal - ccmal - ccmal) + (ccmal - mal - mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg7_221

PKS_AT (4..284): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 96.7
Methoxymalonyl-CoA: 50.0
inactive: 35.3
Methylmalonyl-CoA: 31.5
Propionyl-CoA: 22.2
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg7_223

PKS_AT (7..293): pk

ATSignature: (unknown)

No matches above 50%

minowa: inactive

Prediction, score:

inactive: 30.0
Malonyl-CoA: 23.0
Benzoyl-CoA: 8.8
Isobutyryl-CoA: 8.4
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg7_224

PKS_AT (4..288): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 66.7%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 95.0
inactive: 41.2
Methoxymalonyl-CoA: 29.1
Methylmalonyl-CoA: 22.1
Propionyl-CoA: 16.3
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg7_230

Search NORINE for peptide: strict or relaxed

CAL_domain (60..471): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 16.2
NH2: 10.3
shikimic_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

AMP-binding (1159..1554): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGMIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

ctg7_233

Search NORINE for peptide: strict or relaxed

AMP-binding (497..905): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVsnmAiIYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 60% (weak)

c00011_JABRVC0.. - Region 1 - NRPS

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Location: 104,683 - 159,307 nt. (total: 54,625 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 104682 - 159307:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (glu - leu - D-leu) + (leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg11_120

Search NORINE for peptide: strict or relaxed

AMP-binding (466..867): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAKDLGVVDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 100% (strong)

AMP-binding (1510..1908): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAFMMGMVFK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

AMP-binding (2550..2937): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

ctg11_121

Search NORINE for peptide: strict or relaxed

AMP-binding (469..867): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGCVFK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

c00015_JABRVC0.. - Region 1 - NRPS

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Location: 1 - 14,788 nt. (total: 14,788 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 14788:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-orn) + (tyr - D-thr) + (glu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg15_1

Search NORINE for peptide: strict or relaxed

AMP-binding (256..661): orn

NRPSPredictor2: orn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: orn, horn
Single AA prediction:: orn

Stachelhaus prediction details:

Stachelhaus sequence:: DVGEIGSIDK
Nearest Stachelhaus code:: orn
Stachelhaus code match:: 100% (strong)

ctg15_2

Search NORINE for peptide: strict or relaxed

AMP-binding (474..865): tyr

NRPSPredictor2: tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: tyr, bht
Single AA prediction:: tyr

Stachelhaus prediction details:

Stachelhaus sequence:: DGTITAEVAK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 100% (strong)

AMP-binding (1505..1903): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

ctg15_3

Search NORINE for peptide: strict or relaxed

AMP-binding (469..870): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: glu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWHFGGVDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 100% (strong)

c00016_JABRVC0.. - Region 1 - T3PKS

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Location: 2,223 - 43,320 nt. (total: 41,098 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

c00021_JABRVC0.. - Region 1 - CDPS

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Location: 124,743 - 145,489 nt. (total: 20,747 nt) Show pHMM detection rules used

CDPS: (CDPS or cycdipepsynth)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

c00026_JABRVC0.. - Region 1 - terpene

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Location: 1 - 14,195 nt. (total: 14,195 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

c00032_JABRVC0.. - Region 1 - NRPS

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Location: 1 - 9,994 nt. (total: 9,994 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 9994:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-val) + (pro - glu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg32_1

Search NORINE for peptide: strict or relaxed

AMP-binding (206..599): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DVFWIGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 100% (strong)

ctg32_2

Search NORINE for peptide: strict or relaxed

AMP-binding (469..866): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAHVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 100% (strong)

AMP-binding (1500..1901): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: glu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWHFGSVEK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 100% (strong)

c00033_JABRVC0.. - Region 1 - NRPS

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Location: 4,266 - 51,402 nt. (total: 47,137 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 4265 - 51402:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg33_25

Search NORINE for peptide: strict or relaxed

AMP-binding (463..861): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

AMP-binding (1519..1935): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

ctg33_27

Search NORINE for peptide: strict or relaxed

AMP-binding (31..435): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

c00038_JABRVC0.. - Region 1 - NRPS,betalactone

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Location: 1 - 27,659 nt. (total: 27,659 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 27659:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-tyr) + (ile)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg38_1

Search NORINE for peptide: strict or relaxed

AMP-binding (204..598): tyr

NRPSPredictor2: tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: tyr, bht
Single AA prediction:: tyr

Stachelhaus prediction details:

Stachelhaus sequence:: DGTITAEVAK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 100% (strong)

ctg38_3

Search NORINE for peptide: strict or relaxed

AMP-binding (392..785): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFYGITFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 100% (strong)

ctg38_8

Search NORINE for peptide: strict or relaxed

AMP-binding (13..445): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: N/A
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: gclhIAApvK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 40% (weak)

c00048_JABRVC0.. - Region 1 - terpene

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Location: 27,323 - 48,126 nt. (total: 20,804 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

c00067_JABRVC0.. - Region 1 - NRPS

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Location: 1 - 8,791 nt. (total: 8,791 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 8791:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (val - asp)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg67_2

Search NORINE for peptide: strict or relaxed

AMP-binding (470..864): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWIGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 100% (strong)

AMP-binding (1501..1904): asp

NRPSPredictor2: asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGHIGK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 100% (strong)

c00070_JABRVC0.. - Region 1 - lanthipeptide-class-ii

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Location: 1 - 9,720 nt. (total: 9,720 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

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Gene details

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Lanthipeptides

KnownClusterBlast

Lanthipeptide predictions

Lanthipeptides - No core peptides found.

Similar known gene clusters

No matches found.

Lanthipeptides

Core peptide predictions

No core peptides found.

c00076_JABRVC0.. - Region 1 - sactipeptide

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Location: 1 - 11,896 nt. (total: 11,896 nt) Show pHMM detection rules used

Region on contig edge.

sactipeptide: (subtilosin or thuricin or TIGR04404 or Subtilosin_A or skfc)

Legend:

core biosynthetic genes

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KnownClusterBlast

Sactipeptides

Similar known gene clusters

Sactipeptide predictions

Putative Sactipeptide(s)

ctg76_1 leader / core peptide: MKKAVIVENK - GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

Sactipeptides

Core peptide predictions

ctg76_1: Putative sactipeptide; RODEO score: 33.0; Core sequence, approximate: GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

c00076_JABRVC0.. - Region 2 - other

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Location: 14,637 - 39,661 nt. (total: 25,025 nt) Show pHMM detection rules used

Region on contig edge.

other: (LmbU or Neocarzinostat or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

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resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters