LOCUS       c00076_JABRVC0..       11896 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JABRVC010000008.1 Bacillus subtilis strain CRN 7 S7_contig_8, whole
            genome shotgun sequence.
ACCESSION   JABRVC010000008
VERSION     JABRVC010000008
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-21 00:11:58
            Original ID  :: JABRVC010000008.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11896
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11896
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[284:1896]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      285..1896
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..11896
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11896
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="sactipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     CDS             285..416
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_1"
                     /sec_met_domain="Subtilosin_A (E-value: 9.1e-31, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       285..314
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="ctg76_1"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       315..416
                     /prepeptide="core"
                     /locus_tag="ctg76_1"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[284:314](+)"
     CDS             550..1896
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_2"
                     /sec_met_domain="PF04055 (E-value: 5.4e-24, bitscore: 76.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1082.2, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.4e-09, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.3e-12, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.6e-11, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 5.1e-31,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKAYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     CDS             1909..2070
                     /locus_tag="ctg76_3"
                     /transl_table=11
                     /translation="LSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     CDS             2067..2786
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 127.7; E-value:
                     9.5e-39)"
                     /gene_kind="transport"
                     /locus_tag="ctg76_4"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKMREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVICHE"
     CDS             2779..4089
                     /locus_tag="ctg76_5"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNTYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCLSAALMPAATLPLCAVHMLWAVIIDFPVFLQAPPQQGKMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAVFSGFFSFQMMNTGIFNQQVIYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLLAGGFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPSFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     CDS             4079..5239
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg76_6"
                     /sec_met_domain="Peptidase_M16_C (E-value: 4.4e-07,
                     bitscore: 21.5, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYFYGAAAYLK
                     EQIIDAFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALLKTFADLSFPS
                     SLSFEAVEKARNELLLRIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRKDRIKAIHP
                     KRFLDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSGRIPVNRHVFETETRS
                     AAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAVYHVITRYD
                     VMNNLLLVSICTDQLHEKDIPPRVLEAVSAFHTDERELEQAKQFLRNELLLQFDSPEGL
                     LAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     CDS             5244..6524
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg76_7"
                     /sec_met_domain="Peptidase_M16 (E-value: 2.5e-15, bitscore:
                     48.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDINDLQKAYKAAYQAHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMVLGDEERMEDTWTGLQIGALPGQNDLLSIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     CDS             6521..7222
                     /locus_tag="ctg76_8"
                     /transl_table=11
                     /translation="MIKNTVFTLLLLLIGMAAYSFGWVQAVAEAAAQYVQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDSYKNVRQTYVMAAVLCQVFIFGCMFEIVKAVPFRLHTPPAFSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGVLAAAGIWWMLSFSISELLFLIILAAIQQIGSFIYKR
                     FSYRSTASLDL"
     CDS             complement(7228..8604)
                     /locus_tag="ctg76_9"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIGIPEGFKVDSAEAS
                     AAVTWSTDNLSCISEPCLIQTGPEPEDIGVRYAVRVQGTITLLVSVSPVRNQYGQGDGA
                     VSVIHTEEIDQVVYYAAQSDRCPDFSQMTVEDLLIVPPFYGSPLTVAGTLVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTVVKTIPFSDVPTNLGVTFDKAFTYVLHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPTDEFAYVMAAGSIYVINTASQSVIDVIPIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDVNTGQLVESIIDSFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFSRLFETLMTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVSLPGAFDLAVTPDKQYIYATQPNDNAVTVYRTSDYTAVTVIPVGAGPSAIAM
                     "
     CDS             complement(8643..9998)
                     /locus_tag="ctg76_10"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAIYVIGIDTLTVERSIPVEG
                     FDIAIDPNGLFAYVLNFGLVQKVDLSTGEVLGTIERELIVSSIETDSTERYAYVLEQEF
                     LFNYLTVIDLNTFTIRDTQELEPDGLYVMFTSGSEVYLHDSFTGNLYSVSPNGAGVIGN
                     LPQSATDYAFTPNGDFLYATRFIEQSIIVYNTDDYSEETVISLGVSPGAITI"
     CDS             10228..11373
                     /locus_tag="ctg76_11"
                     /transl_table=11
                     /translation="VTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDY
                     ARQAYEIYKENEAYNIRLLQCHSLFATNFLDLKQYEDAISHFQKAYSMAEAEKQPQLMG
                     RTLYNIGLCKNSQSQYEDAIPYFKRAIAVFEESNILPSLPQAYFLITQIHYKLGKMDKA
                     HEYHSKGMAYSQKAGDVIYLSEFEFLKSLYLSGPDEEAIQGFFNFLESKMLYADLEDFA
                     IDVAKYYHERKNFQKASAYFLKVEQVRQLIQGGVSLYEIEV"
     CDS             11357..11476
                     /locus_tag="ctg76_12"
                     /transl_table=11
                     /translation="MKLKSKLLLFCLALSTVFVATTIANAPTHQIEVAQRGMI"
     CDS             11574..11741
                     /locus_tag="ctg76_13"
                     /transl_table=11
                     /translation="MSLKSVRTHFTQWNRENDVTEFETSSATVEQAAETIGVSLSRIAK
                     SLSLEGKEIR"
ORIGIN
        1 ttgacttgaa tagtataatc attcggtttg taaacttcaa ctgcttctat cttaccatca
       61 ttgctcatca gatttgaaga taaacctcat aaaaagcatt tccttatata gaagagaaaa
      121 tcatatcact aattaccttt aggaaatgtt acatttttcc gaaatctatc attttctttt
      181 cacatttttt tcaaattata tgtattgaat tagtaatttg atagttttaa gataaaagta
      241 caacatagat ctgctagaaa aacaaaaaaa gggaggattc aattatgaaa aaagctgtca
      301 ttgtagaaaa caaaggttgt gcaacatgct cgatcggagc cgcttgtcta gtggacggtc
      361 ctatccctga ttttgaaatt gccggtgcaa caggtctatt cggtctatgg gggtagagat
      421 ctcccaaaag ggcatagtca ttctactatg ccctttttaa gtaaattaca atttttaact
      481 aaaatctacc tcttggatat acatacacaa ccgtttttca tttgaatcat atgtataggg
      541 gatggtattt tgtttataga gcagatgttt ccatttatta atgaaagtgt aagagttcac
      601 cagcttcctg agggcggcgt gttagaaatc gactacttgc gcgataatgt ctccatttct
      661 gacttcgagt atttggatct caacaaaacg gcttacgagc tctgcatgcg catggatggc
      721 caaaaaacag ctgagcagat tttagctgag caatgtgcag tgtatgatga atcaccggaa
      781 gaccataaag attggtatta cgacatgctc aacatgctcc agaacaagca ggttattcag
      841 cttggaaacc gggccagccg ccatacaatc accacgagcg gaagcaatga atttccgatg
      901 cccctgcacg ccacctttga actgacgcac cgctgtaatt tgaaatgcgc ccactgttat
      961 ttggaaagct cacctgaagc gctcggcacc gtgtcgattg agcaattcaa aaaaacggct
     1021 gatatgctgt ttgataacgg tgtattgaca tgcgaaatca caggcggaga aatttttgtc
     1081 catccaaacg ccaatgagat tcttgactat gtgtgtaaaa agttcaaaaa agtcgctgtc
     1141 ttaacaaacg gaacactcat gcgaaaagag agtttggagc ttttgaaggc ttacaagcaa
     1201 aaaatcatcg tcggcatttc tcttgatagt gtcaattccg aggtccatga ctcctttaga
     1261 gggagaaaag gctcttttgc ccaaacttgt aaaacgataa aattgttgag tgaccacggt
     1321 atatttgtca gagtcgccat gtctgtcttc gaaaaaaaca tgtgggaaat ccacgatatg
     1381 gcccaaaagg ttcgggatct cggggcgaag gcgttttctt acaattgggt tgatgatttc
     1441 ggaagaggca gagatattgt ccatccaacg aaagacgccg agcagcaccg caagtttatg
     1501 gaatacgagc aaaatgtgat tgatgagttt aaagatctga ttccgattat tccctatgag
     1561 agaaaacgcg cggcaaattg cggcgctggc tggaagtcca ttgtgatcag cccgttcggc
     1621 gaagtacgtc cttgcgccct ctttccaaag gaattttcat tgggaaatat ttttcatgat
     1681 tcctatgaaa gcatctttaa ctcccctctc gtccataaac tgtggcaagc gcaagcgccg
     1741 cggttcagcg aacattgcat gaaagacaaa tgcccgttca gcggctattg cggaggctgt
     1801 tacttaaaag ggctgaactc taacaaatat caccggaaaa acatttgctc ttgggcgaaa
     1861 aatgaacaat tagaagacgt ggtccagctt atttaggagg gaaacgattt gtcaccagca
     1921 caaagaagaa ttttactgta tatcctttca tttatctttg tcatcggcgc agtcgtctat
     1981 tttgtcaaaa gcgattatct gtttacgctg attttcattg ccattgccat tctgttcggg
     2041 atgcgcgcgc ggaaggctga ctcgcgatga gcattttgga tatacacgat gtatccgttt
     2101 ggtatgaacg ggacaacgtc atcttagaac aagtggattt acatttagaa aaaggtgccg
     2161 tttacgggtt gcttggggta aacggcgccg gaaaaacgac actgattaat acgctgacag
     2221 gcgtgaaccg caatttcagc gggcgcttta cactgtgcgg aattgaagcg gaggccggca
     2281 tgccgcagaa aacatcagat cagctgaaga ctcaccgtta cttcgccgcc gattatccgc
     2341 tgctatttac agaaattacg gcgaaggact atgtgtcttt cgtccattcg ctttatcaaa
     2401 aggatttttc agagcagcag tttgccagtt tggccgaggc ctttcatttt tcgaaataca
     2461 tcaacaggag aatttcggag ctgtccttgg ggaacaggca aaaggttgta ttgatgacag
     2521 gcttattgct gcgcgctccc ctgtttattt tggatgagcc gctcgtcggt ttggatgtgg
     2581 aatcgataga ggttttttat cagaaaatgc gcgagtactg tgaagcaggc gggaccattt
     2641 tgttttcttc tcatctgctc gatgtcgtgc aaagattttg tgattatgcg gctattcttc
     2701 acaacaaaca gatccaaaag gtcattccga ttggagagga gaccgatctg cggcgggaat
     2761 tttttgaggt gatctgccat gaataacata atccctatca tgtctttgct gttcaaacag
     2821 ctttacagcc ggcaagggaa aaaggacgcc atccgcattg ccgcaggcct tgtcattctg
     2881 gccgtgtttg aaatcgggct gatccgccag gccggcattg atgaatcggt gttgcgcaaa
     2941 acgtatatca tactcgcgct tcttttgatg aacacatata tggtgtttct ttccgtgaca
     3001 tctcaatgga aggaatctta tatgaaactg agctgcctgc tgccgatttc ttcacggagc
     3061 ttttggctcg cccagagtgt cgttttgttt gtcgatacct gtttgagaag aactttattc
     3121 ttttttattt taccgctgtt cttatttgga aacggaacgc tgtcaggggc gcaaacattg
     3181 ttttggctcg gcaggttttc gttttttacc gtttactcca ttattttcgg agttgtgcta
     3241 agcaaccact tcgtcaaaaa gaagaacttg atgtttctgc tgcatgcggc gatattcgcc
     3301 tgtgtatgtc tcagcgctgc tttgatgccg gccgccacgc ttccgctttg cgcggtgcat
     3361 atgctgtggg cggtgatcat tgactttcct gtctttctgc aggcgcctcc gcagcagggc
     3421 aagatgcatt catttatgcg gcgatctgaa ttttcgtttt acaaaagaga atggaaccga
     3481 tttatctctt ctaaagcgat gctgttaaat tacgcggtaa tggcggtatt cagcggcttc
     3541 ttttcgttcc agatgatgaa caccggcatc ttcaatcagc aagtgattta tatcgtgatt
     3601 tccgcgcttt tgctcatctg ctcgccgatc gcccttttgt actcgattga aaaaaatgac
     3661 cggatgttgc tcatcacgct tccgatcaag cggaaaacga tgttttgggc gaaatatcgc
     3721 ttttattcag gcctattggc aggcggattt ctccttgtcg tgatgattgt gggtttcatc
     3781 agcggccgtc cgatttcagt tctcactttt ttgcagtgca ttgagttgct gctggcggga
     3841 gcttttatca ggttaactgc ggatgaaaaa aggccctcct tcagctggca gacggagcag
     3901 cagctatgga gcggtttctc aaaatatcgg tcttatctgt tttgtcttcc cctattctta
     3961 gccacattag ccggcaccgc tgtatccttg gcggtcattc cgatagccgg tctggtcata
     4021 gtctattacc tgcaaaaaca ggatggtggt ttctttgata caagcaaaag agaacggctt
     4081 ggaagttaac ctgctgaaga ctcatcaatt ttcaactatt tcaatcgccg cgagctttct
     4141 gaaaccaatc gaaagcgcgg cggaacctga ggaagaaaca atttattttt acggcgccgc
     4201 cgcatacctg aaggagcaaa tcattgacgc tttcggttgt gctgccggca gccgtttcat
     4261 gtactcagcg aatctctttt ttgatcagca gctgaaaacc tgcgggaccc gtttgattca
     4321 cccattatat aacgggaatc ttcatgttga cgccctgctg aaaacttttg cagacttgtc
     4381 tttcccttct tctctttcat tcgaagcagt tgaaaaggcc aggaatgagc tgctgctgag
     4441 aatcgaaaag aaattcactg atcctttctc ctactcggcg gcgcgcttgg ctgaggaggt
     4501 cttcggaaac ccgatgtacg gcacaggcat gtttggccgg aaagacagga taaaggcgat
     4561 tcatcctaaa cggtttctcg acgcaacgga ctttatcgtt gatttagtgt cccagcaaaa
     4621 acagctgaac atattgggac aagtacaagc atgtgatgtt cggggacatg ccccgcaaac
     4681 gtccgctgta acgtccggaa gaatacccgt aaaccggcat gtttttgaaa cagagacacg
     4741 cagcgctgca ggtccttccg tcttgacact cggatttgac tgcggagaga tgaaagatgc
     4801 cagcgattat atcaaaatac agctaataga cggattactg ggaaagtacg gccattccgc
     4861 tttattcaag cacttcagag agaaggatct ggcagtctat cacgttatca cccgttacga
     4921 tgtcatgaac aatttgctgc ttgtttcaat atgtacagat cagcttcatg agaaagacat
     4981 tcccccgcgc gttttggaag ctgtctcagc ttttcataca gatgagcggg aactagaaca
     5041 ggcaaagcag tttttacgca atgaattgct gctgcaattc gattctcccg aaggtctatt
     5101 ggcctatatg gggatcctgc gccgcttctc ctgcacgaaa gaagccttgc tggatggcat
     5161 ctcagcggtt acatgccgtg atgtattgca attcatagcg accatcaatt atatcggagc
     5221 tcatgtagta aggggatgaa gagatggaaa agaaagcctt ttttcaacag ctggatgaac
     5281 gaaccgatat cagatacaca gacagcggac taaaaatatt cagattgaaa ttcccccgcg
     5341 cccacctgcg gctgtgcaat gtaaaaatcg attttggaag ccgggatgta tgtatacggg
     5401 cagaatccgg tgatacactg cttccgtatg gcacagcgca ttttttagag catcttcttt
     5461 tctggcataa cggccgcaat ctgtacagtg atttttttgc gcatggcgcg cttttaaacg
     5521 cattcactac ctacaccgat accaatttca tgtttacctc attaccggat cggctcagac
     5581 aaacgatccc catcctgctt gatgctttat ggaaccactc atttgacaag aagattgtcg
     5641 ctcaggaaaa agctgtgatt acaagcgaaa ttcaaacagc acaccttaac catcagctct
     5701 catatcatta tcagctgatc agcatgcttt ctccctcctc accagctgcc gttttccccg
     5761 caggcagaat cgaagatatt gaggcgctgg acatcaatga tttacaaaaa gcctataagg
     5821 ctgcctacca agcccatcgg atgacactgt ttttgattgg gggctcagaa aatacagaaa
     5881 cgcttttgcc tcctcacctc cagctggaaa agcgtccgga ttatcatgct gaaagaaaaa
     5941 tcatcccggc atgccctcca gccctctcac aaaaaatggt gctgggtgat gaggagcgga
     6001 tggaagatac ttggaccgga ttacagatcg gcgcacttcc cgggcaaaac gatctgttgt
     6061 cgataaagct ttattgggat atcgcggctc gtattctatt tcaattagat tcaccgtttt
     6121 ttcaagagat tcagcaaacg taccgtctgg aaatcgatcg cttgtcagcc gagacttata
     6181 tatatgagga tggcggtttc ttgatccttc acagtcaagg gacccattct tcagcttata
     6241 tcgatgtggc ttcatactat gtcacacaga agaaagaaca ggttgccgcc tggcttcaat
     6301 acggcaagga ctctttgaca gacgcgatca tttatgacag cgattatgtg cgtaaatgct
     6361 tcgagtgggc agccgagtgt gacaggtgcg attgctcgtt tcttgacatg taccacatca
     6421 ttcaagatat ggatgcgcag gttttcttgt ctctcattga tgcaatggca tcttctaaca
     6481 aagcgatcat tcatgtttct cagaaagagg cgatcagaca atgataaaaa acactgtctt
     6541 taccctttta ttgctgctta taggtatggc ggcttattcc ttcggctggg ttcaggccgt
     6601 ggccgaagcc gccgcccaat atgtacagat gatcaacaat gacgctgtgc ggctcgggct
     6661 gctggcttgt accgctgccc tcctgatgct gcctgctttt ctctatcttc actatgtcac
     6721 ccaatccgtg aaaaacatga cagcagcttt tcagaaactc acacagtctc atcaaagctg
     6781 ctgtgacttt cagcaacaca acttgtgcag ccgatatgca gaagacgtca aatcgctgcg
     6841 tgacagctat aaaaacgtcc gccaaacata cgtgatggct gccgtgttgt gccaagtctt
     6901 catattcggc tgcatgttcg aaatcgttaa agccgtccct ttccgccttc atacgccccc
     6961 tgccttttca atgggacttg cgatgctact gatcctgtat ttattgtttt gcatgcgaac
     7021 gtatttgcgg cagcttttcc ggcacggcag cctgttcaga aaagtgtttg cgggagtgct
     7081 ggcagcagcc gggatttggt ggatgctcag tttctctata agtgaactgc tgtttctgat
     7141 tatcctggct gccattcagc aaatcggatc atttatttat aaacgattct cttatcgcag
     7201 caccgcttct cttgatctat aaaatagcta catcgcaatc gcagacggac ccgcgccaac
     7261 cggaatcacc gtcacggctg tataatcact tgtgcggtac acggtcacag cattgtcgtt
     7321 gggctgtgtc gcataaatat actgtttgtc cggcgttacg gcgaggtcaa aggcgccggg
     7381 gagagacacg tttgcaatga tcctctgtct ggccgtatta actacatata agttattaat
     7441 gagaaacggt tcactatatg gctctagaaa ataagctcta gtactatcga gagaaaatac
     7501 aatcgtcatc agcgtttcaa ataaacggct gaagtcccct cccctgctta atggagacaa
     7561 actaatctcc gttacacctt tcggccacag ctcaccattc aacacgtacg caaaatttcc
     7621 agcgtaagga gtcgcaatta aactgggaaa ttcaaatgaa tctatgatac tttctaccaa
     7681 ctgcccagta tttacatcat atttatcaac cgaccaactg cttccattag cggtatagac
     7741 atactgtcca ttcggatcaa gagcaaagtc taaagcgccg ggtatcggaa tgacatcaat
     7801 gaccgattga gaggccgtgt taatcacata tatagatccg gcggccatca cgtatgcgaa
     7861 ctcatctgtt ggatcaaatt cgatctttct cggccctcct ccaacagtaa tggtatttat
     7921 gatggttaat gttttattat caatcactga gacaaggttg gtatttccat ggaggacata
     7981 cgtgaatgct ttatcgaaag taacgcctag attagttggc acgtcagaaa aagggattgt
     8041 ttttacaaca gtgtttaaat ctgcatcaat aaccgaaacc gtgctgtctc cagtattggc
     8101 agtaaacaca tacgattgag gatctggtga tggcggtaaa acaagtgtcc cggccaccgt
     8161 aagcggactg ccgtaaaaag gcggtacaat gagcagatct tccactgtca tttgactaaa
     8221 atcaggacag cggtcagact gtgctgcata ataaacaact tgatcaatct cttcggtatg
     8281 aatcacagaa acagccccgt ctccttgtcc atattgattt cgtacaggcg acacactgac
     8341 aagaagcgta atggtccctt gtactctcac ggcatatcga acaccgatat cttctggttc
     8401 cggcccagtc tggattaagc aaggctcact gatacaggac aaattgtctg tactccatgt
     8461 aacagccgct gacgcttctg ccgaatcaac cttgaagccc tcagggatac ctatcggcac
     8521 ttgaaacggc gcttcccggc taatttcctc atcacaaaaa cagaaacaat tttcctgtaa
     8581 agcagaaaga tcattctttt tcatgatttc acgtcctttt agaaatgcac aacatgcagc
     8641 ggttaaatcg taatggcacc cggtgaaacc ccaagagata tcacagtttc ctcagaataa
     8701 tcatctgtgt tgtaaacaat gatgctctgc tctataaaac gagttgcata cagaaaatcg
     8761 ccattcgggg taaacgcata gtctgttgct gattgcggaa gatttccaat tacacctgct
     8821 ccattcggac tgacagaata taaattgcca gtgaagctgt catgtaaata cacctctgat
     8881 ccactcgtaa acattacata tagcccgtca ggctccagct cttgggtatc cctgatcgta
     8941 aacgtattta aatcaataac cgtcaaataa ttgaataaga attcttgttc taatacatac
     9001 gcataccgct ccgtagaatc tgtttctatg gatgatacga taagctctcg ttcaatcgtt
     9061 cctaagactt caccggtaga taagtccact ttttgcacta acccaaaatt aagaacatag
     9121 gcgaacaacc cattggggtc aattgcaata tcaaaacctt ctacaggaat agacctctca
     9181 acagtcaacg tatcaattcc aatcacataa atggcagtac cggtgaaaac ataagcaaac
     9241 tcatgattag ggataaatct aatcaatcga ggcggctgat ccagcaatat agttgctgtc
     9301 actgttaatg tgtcataatc gatgacagaa atcacattat tgttgggatg taagacaaac
     9361 acagcgcttt tatctggcgt aatttcaata cctgccggat tgtacggaag agcaatcgtt
     9421 gtcacaacag tatgggtgtt tgtatcaatc acagaaactg attgatcatt tggattcgct
     9481 gtaaacgcgt agacgggttc cggctccggt acaagcacaa tcgtccccgt caccgataaa
     9541 ggactgccgt aaaacggcgg aacaacaaca aggttctcaa tcgtgatgtc actgatatcc
     9601 gggcaatcat ccggttcatc ggaataatag acgacttgat cgatttctgc attgtgaatg
     9661 acggaaacag ccccgtcccc ttgtccatat tgatttcgta caggtgagac actgacgagt
     9721 agcgtaacgg ttccctgcag gcgcactgca aattgaacac cgacctcatc aggctctggc
     9781 cccgtttgaa ttaagcaacg gtcactgaca caagaaaggc tgtctgcatt ccacgtcacg
     9841 tttgcaacag cttcagccgg atcaacgaca aatccttcag gtaattcaat cggcgcttga
     9901 aacatggctt ctcggcttgc ttctccctca caaaaacata agcactcttc ttgttctgct
     9961 cctgcttttt ctttaaagga aagcttattt tttctcattc cttcacttcc ttttcagaca
    10021 tacactgctc acgcagatat aacagaatat ggaagagtaa cgtgtttgct tgtacaaatt
    10081 actgagggta aacgcttctt tttgaaaata tatctccaaa catgcggtgt aacgaaagaa
    10141 aaaattgcgg tttttttgcg cttctcacaa gaatgttgat gataaaatat gacatatata
    10201 gaattatgaa gggagggatt tgcaaacgtg acaggtgtca tatcttcttc ttccatcgga
    10261 gaaaagatta acgaatggta tatgtacata cgccgattca gcatacccga tgcagaatat
    10321 ttgcgacgag aaatcaagca agagctggat caaatggaag aagatcaaga ccttcatttg
    10381 tactattcac tgatggagtt tcggcacaac ctaatgcttg agtaccttga accgttagaa
    10441 aaaatgagga ttgaggaaca gccgagactg tctgatctgc tgcttgagat tgataaaaaa
    10501 caggctcgtt taactggtct gcttgagtac tattttaatt tcttcagagg catgtatgag
    10561 ctggaccagc gggaatatct gtcggctatt aaatttttca aaaaggccga aagcaagctg
    10621 atattcgtta aggatcggat agagaaagct gagtttttct ttaagatgtc tgaatcttat
    10681 tactatatga aacaaacgta tttttcaatg gactatgcac ggcaagcata tgaaatatac
    10741 aaagaaaatg aagcttataa tataagattg ctgcagtgtc attctttatt tgccaccaat
    10801 tttttagatt taaaacagta tgaggatgcc atctcacatt ttcaaaaagc ttattctatg
    10861 gcagaagctg aaaagcagcc ccaattaatg ggaagaactt tgtacaatat cgggctttgt
    10921 aaaaacagcc aaagccaata tgaggatgcc ataccttatt tcaaaagagc aatagctgtt
    10981 tttgaagaat caaatattct tccttcctta cctcaagcgt attttttaat tacacagatc
    11041 cattataaat taggaaaaat ggataaagct catgaatatc atagtaaggg aatggcttat
    11101 tcacaaaagg ccggagatgt aatatattta tcagagtttg aatttttgaa atctttatac
    11161 ttatcaggcc cggatgaaga agcaattcaa ggatttttta attttctcga aagtaaaatg
    11221 ttgtatgctg atcttgaaga tttcgctatt gatgtggcaa aatattatca tgaacgtaaa
    11281 aattttcaaa aagcttctgc ttattttttg aaggtggaac aagtaaggca acttattcaa
    11341 ggaggagtga gtttgtatga aattgaagtc taaactatta ctcttttgtc tggctctaag
    11401 cactgtgttc gtggcaacaa ctattgcaaa tgcacctaca caccaaattg aagttgcaca
    11461 acgaggaatg atttaaccgc cgtccatcgg cggttttttt gtcccctctt tacccagtct
    11521 cccaatccat tctatgattt tttcaataat cttaaaaata gtggaaatgc agcatgtctc
    11581 taaaaagtgt gagaacccac tttactcaat ggaatcgaga aaatgatgtg acggagttcg
    11641 aaacgtcgag tgcgaccgtt gaacaggcag ctgagacaat cggcgtaagc ctgtctagaa
    11701 tcgccaagtc cctgtcctta gaggggaagg agatcaggtg attctgattg tggcagcggc
    11761 gatgccaaga tcgacaacaa aaagtccagg caaacatttg gctttaaagc aagaatgctc
    11821 tctcctaatg aggtgctgga gcagacaggc catgaaattg gaggagtttg cccatttgga
    11881 ttggctcatg atcctg
//
