LOCUS       c00195_JABRVE0..       13991 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JABRVE010000089.1 Bacillus subtilis strain CRN 11 S11_contig_89,
            whole genome shotgun sequence.
ACCESSION   JABRVE010000089
VERSION     JABRVE010000089
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2022-06-21 13:15:12
            Original ID  :: JABRVE010000089.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3814
            Orig. end    :: 17805
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13991
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[13814:17106]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13292
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..13991
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13991
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(1101..2363)
                     /locus_tag="ctg195_4"
                     /transl_table=11
                     /translation="MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEI
                     VEEELGTEEEVEFKDVPKPQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDD
                     VELSKSNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLI
                     QAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQ
                     GGRKHPHQEFIQIDTTNILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLL
                     SKVLPEDLLRFGLIPEFIGRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNV
                     ELEFEEEALSEIAKKAIERKTGARGLRSIIEGIMLDVMFELPSRDDIEKCVITGATVTH
                     GEPPRLLLKDGTEVSQDKTSA"
     CDS             complement(2635..3909)
                     /locus_tag="ctg195_5"
                     /transl_table=11
                     /translation="MSVKWEKQEGNEGVLTVEVDAETFKTALDDAFKKVVKQVSIPGFR
                     KGKIPRGLFEQRFGVEALYQDALDILLPVEYPKAVEEAGIEPVDRPEIDVEKIEKGESL
                     IFTAKVTVKPEVKLGDYKGLGIEKDDTTVTDEDVQNELKALQERQAELVVKEEGAVEEG
                     NTVVLDFEGFVDGEAFEGGKAENYSLEVGSGSFIPGFEDQLVGLEAGAEKDVEVTFPEE
                     YHAEDLAGKPAVFKVKIHEIKAKELPELDDEFAKDIDEEVETLAELTEKTKKRLEEAKE
                     NEADAKLREELVLKASENAEIDVPQAMVDTELDRMLKEFEQRLQMQGMNLELYTQFSGQ
                     DEAALKEQMKEDAEKRVKSNLTLEAIAKAENLEVSDEEVDAELTKMAEAYNMPVENIKQ
                     AIGSTDAMKEDLKVRKAIDFLVENR"
     CDS             complement(4137..5141)
                     /locus_tag="ctg195_6"
                     /transl_table=11
                     /translation="MTHDKKNAKIIPFPHLKDRLVEKGMSSLKEKKYQEALELFSEAMK
                     YDDTEADLHLGMAICFLELGELEEAKSVCEKMLKEGYGHYFTVLQVYMTILIQLKKYEE
                     VKSTIEAVLEENQLPAESAEQFYKLLDFSRKMTDPDREDEAWAEEYEDTIDTEKVLASP
                     EEQMNLIHSLKDRNVAKYTGLLKTILQDPSAHPIIKTMIVMLLAEHEYSKPVHISKFGE
                     SLTIEPSEIVPPDAAPILHRVLRVLDETLGNENPTLYAAVEELWRRHLYVLYPFQPKLL
                     SADLWAAALHKVGYEMHGIEIESEELHMMYEFTDRELDEACTMLKDIEEISYL"
     CDS             complement(5260..5859)
                     /locus_tag="ctg195_7"
                     /transl_table=11
                     /translation="MEPLKSHTGKAAVLNRINVDTDQIIPKQFLKRIERTGYGRFAFFD
                     WRYDANGEPNPEFELNQPVYQGASILIAGENFGCGSSREHAPWALDDYGFKIIIAPSFA
                     DIFHQNCFKNGMLPIRMPYDNWKQLVGQYENKSLQMTVDLENQLIHDSEGNQISFEVDS
                     HWKEMLINGYDEISLTLLLEDEIKQFESQRSSWLQD"
     CDS             complement(5872..7290)
                     /locus_tag="ctg195_8"
                     /transl_table=11
                     /translation="MMPRTIIEKIWDQHIVKHGEGKPDLLYIDLHLIHEVTSPQAFEGL
                     RQKGRKVRRPQNTFATMDHNIPTVNRFEIKDEVAKRQVTALERNCEEFGVRLADLHSVD
                     QGIVHVVGPELGLTLPGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLSTQTLWQQRP
                     KTLEVRVDGTLQKGVTAKDVILAVIGKYGVKFGTGYVIEYTGEVFRNMTMDERMTVCNM
                     SIEAGARAGLIAPDEVTFEYCKNRKYTPKGEEFDKAVEEWKALRTDPGAVYDKSIVLDG
                     NKISPMVTWGINPGMVLPVDSEVPAPESFSAEDDKKEAIRAYEYMGLTPHQKIEDIKVE
                     HVFIGSCTNSRMTDLRQAADMIKGKKVADSVRAIVVPGSQSVKLQAEKEGLDQIFLEAG
                     FEWRESGCSMCLSMNNDVVPEGERCASTSNRNFEGRQGKGARTHLVSPAMAAMAAIHGH
                     FVDVRKFYQEKTVV"
     CDS             complement(7340..8437)
                     /locus_tag="ctg195_9"
                     /transl_table=11
                     /translation="LKKRIALLPGDGIGPEVLESATDVLKSVAERFNHEFEFEYGLIGG
                     AAIDEHHNPLPEETVAACKNADAILLGAVGGPKWDQNPSELRPEKGLLSIRKQLDLFAN
                     LRPVKVFESLSDASPLKKEYIDNVDFVIVRELTGGLYFGQPSKRYVNTEGEQEAVDTLF
                     YKRTEIERVIREGFKMAAARKGKVTSVDKANVLESSRLWREVAEDVAQEFPDVKLEHML
                     VDNAAMQLIYAPNQFDVVVTENMFGDILSDEASMLTGSLGMLPSASLSSSGLHLFEPVH
                     GSAPDIAGKGMANPFAAILSAAMLLRTSFGLEEEAKAVEDAVNKVLASGKRTRDLARGE
                     EFSSTQAITEEVKAAIMSENTISNV"
     CDS             complement(8458..10014)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg195_10"
                     /sec_met_domain="HMGL-like (E-value: 3.4e-100, bitscore:
                     324.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LRKINFFDTTLRDGEQSPGVNLNTQEKLAIAKQLERLGADIIEAG
                     FPASSRGDFLAVQEIARTIKICSVTGLARCVKGDIDAAWEALKDGAQPRIHVFIATSDI
                     HLKHKLKMTREQVIERAVEMVRYAKERFPIVQWSAEDACRTELPFLAEIVEKVIDAGAS
                     VINLPDTVGYLAPAEYGNIFRYMKENVPNIHKAKLSAHCHDDLGMAVANSLAAIENGAD
                     QIECAVNGIGERAGNAALEEIAVALHTRKDFYQVETGITLNEIKRTSDLVSKLTGMAVP
                     RNKAVVGDNAFAHESGIHQDGFLKEKSTYEIISPELVGVTADALVLGKHSGRHAFKDRL
                     TALGFQFDSEEINKFFTMFKELTEKKKEITDEDLVSLILEEKVTDRKIGYEFLSLQVHY
                     GTSQVPTATLSLKNQENAELIQEAATGAGSVEAIYNTLERCIDKDVELLDYRIQSNRKG
                     EDAFAQVYVRVLVNGKESAGRGIAQDVLEASAKAYLNAVNRQLVFQSNMSGLKNHTAVG
                     S"
     CDS             complement(10001..11029)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg195_11"
                     /sec_met_domain="IlvN (E-value: 1.2e-78, bitscore: 252.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 4.3e-69, bitscore: 221.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKVYYNGDIKENVLAGKTVAVIGYGSQGHAHALNLKESGVDVIV
                     GVRQGKSFTQAQEDGHKVFSVKEAAAQAEIIMVLLPDEQQQKVYEAEIKDELTAGKSLV
                     FAHGFNVHFHQIVPPADVDVFLVAPKGPGHLVRRTYEQGAGVPALFAIYQDVTGEARDK
                     ALAYAKGIGGARAGVLETTFKEETETDLFGEQAVLCGGLSALVKAGFETLTEAGYQPEL
                     AYFECLHELKLIVDLMYEEGLAGMRYSISDTAQWGDFVSGPRVVDAKVKESMKEVLKDI
                     QNGTFAKEWIVENQVNRPRFNAINASENEHQIEVVGRKLREMMPFVKQGKKKEAVVSVA
                     QN"
     CDS             complement(11053..11571)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg195_12"
                     /sec_met_domain="ALS_ss_C (E-value: 2.4e-32, bitscore:
                     101.0, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKRIITLTVVNRSGVLNRITGLFTKRHYNIESITVGHTETAGVSR
                     ITFVVHVEGENDVEQLTKQLNKQIDVLKVTDITNQSIVQRELALIKVVSAPSTRTEING
                     IIEPFRASVVDVSRDSIVVQVTGESNKIEALIELLKPYGIKEIARTGTTAFARGTQQKA
                     SSNKTISIV"
     CDS             complement(11568..13292)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg195_13"
                     /sec_met_domain="TPP_enzyme_C (E-value: 9.4e-56, bitscore:
                     177.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTNVQVDSASAKCTQTMSGALMLIESLKKEKVEMIFGYPGGAVL
                     PIYDKLYNSGLVHILPRHEQGAIHAAEGYARVSGKPGVVIATSGPGATNLVTGLADAMI
                     DSLPLVVFTGQVATSVIGSDAFQEADILGITMPVTKHSYQVRQPEDLPRIIKEAFHIAT
                     TGRPGPVLIDIPKDVATIEGEFSYDHEMNLPGYQPTTEPNYLQIRKLVEAVSSAKKPVI
                     LAGAGVLHGKASEELKNYAEQQQIPVAHTLLGLGGFPADHPLFLGMAGMHGTYTANMAL
                     HECDLLISIGARFDDRVTGNLKHFARNAKIAHIDIDPAEIGKIMKTQIPVVGDSKIVLQ
                     ELIKQDGKQSDSSEWKKQLAEWKEEYPLWYVDNEEEGFKPQKLIEYIHQFTKGEAIVAT
                     DVGQHQMWSAQFYPFQKADKWVTSGGLGTMGFGLPAAIGAQLAEKDATVVAVVGDGGFQ
                     MTLQELDVIRELNLPVKVVILNNACLGMVRQWQEIFYEERYSESKFASQPDFVKLSEAY
                     GIKGIRISSEAEAKEKLEEALTSREPVVIDVRVASEEKVFPMVAPGKGLHEMVGVKP"
     CDS             complement(13356..13544)
                     /locus_tag="ctg195_14"
                     /transl_table=11
                     /translation="MTVGLGRVNLIHSLLKRIEISMRRPTKAVNKGGTAERKAFSPLLA
                     IAVTARLIVGGRAFFIE"
ORIGIN
        1 gccatccccg ctgcgatttg aatcatattg acggcttccc gcccgttcct cgtgtagctg
       61 gtcaaaagat ctaggccttc ttcggagata tttttttcaa ttttatccgc tgctgtttta
      121 gcaaccgttt tcagctcgtc cttttcaagc tcgcggaaaa aaacctccaa acagcgggac
      181 ctgatagctg gcggaatctc gtttggcatt ctcgtggtcg cgccaatcaa gcgaaaatca
      241 gccggcagcc cattttgaaa aatatcatga atatgattcg gaatttgtgt attttcctca
      301 ctgtaatacg cactgtctaa aaagactttt ctgtcctcaa gcaccttcag cattttattc
      361 atttgaatag gatgcagctc ccctatttca tcaataaaca gcacaccgcc atgggcatgg
      421 gtgacagccc cctgcttcgg ctgcggaatc ccagcctgtc ccatcgctcc ggccccttgg
      481 tatatcgggt catggacaga gccgatgagc ggatcggcaa ttcctctttc atcaaaacgg
      541 gctgttgtcg catcgagttc cacaaaaaca gcctgctctt taaacggtga ttgtttatgt
      601 ttttttgctt cttccaacac aagccgcgca gcagccgttt tcccaactcc cggtggccca
      661 tagacaatca catgctgagg atttggcccg cataaagccg cctttaatgc ttttatgccg
      721 tcttcctgtc cgacgatatc ttgaaagctt ttggggcgga ccttctcaga taatggctcg
      781 gacaagctga tagcgcgcat tttccgaagc tgctccattt ccttctttga ttctttatct
      841 atcgtgacct tttgtgtcct ttgattttta agcaaattcc aaaaatacaa accaatgatg
      901 atcccaaaaa acagctgaat aaataacgcg atccctgtcc aactcatggt ggtccctcct
      961 gaaaaacaat ttatgtatcc aattcattcc tctgattgct agtatctccc ataggaggcg
     1021 ggaataaacg tttttccgga agagtttgca tgcaaaaaaa acctcctgag tgttaccact
     1081 caggaggttt gtgcttatct ttatgcagat gttttatctt ggcttacctc agtgccgtct
     1141 tttaataaga ggcgaggagg ctctccgtgt gtcacagttg ccccggtaat tacacatttt
     1201 tcaatgtcat cacgagaagg cagctcaaac ataacatcaa gcatgatgcc ttcaatgata
     1261 gaacggagtc cgcgtgctcc agtcttgcgt tcaattgctt ttttagcaat ttcagaaagc
     1321 gcttcttctt caaactcaag ctcaacgttg tcaagctcaa gcattttctt gaattgctta
     1381 acaagagcgt ttttcggttt tgttaagatc gcaaccaatg cttcttcgtc aagcttttca
     1441 aggcttgcaa taaccggaag acgtccgata aattcaggaa ttaacccgaa acggagcaaa
     1501 tcttcaggaa gcacttttga aagaagatct tctttctcaa gatcagcagc tttattgtcg
     1561 gcaccgaatc caatcacttt ttggcctaaa cggcgtttga tgatttgttc gataccatcg
     1621 aaagctccgc cgcaaatgaa caaaatattt gttgtgtcaa tttgaatgaa ttcttgatga
     1681 ggatgcttac gtccaccttg aggcggcacg cttgccactg taccctcaag aattttaagc
     1741 aatgcctgct gtacaccctc acctgacaca tcacgtgtga tagacgggtt ttcagatttt
     1801 ctagccactt tatcgatttc atcaatatag ataatgcctt tttcggcttt ttccacatca
     1861 taatcagcag cttggatgag cttcaagaga atattctcta catcttcacc cacgtatcca
     1921 gcttcagtca aagatgtagc gtctgcaatc gcaaacggca catttaaaat gcgagccaat
     1981 gtttgcgcca gaagggtttt accgcttccc gtagggccga ttaatgaaat attacttttt
     2041 gaaagctcaa catcatcaac tttgctgtta gagttaatgc gcttatagtg gttatacaca
     2101 gcaacagcaa gtgatttctt cgcttgatct tggccgatga catattcatt caaaatttcg
     2161 cgaatttcct gaggctttgg tacgtcttta aattctactt cttcttctgt tccgagttct
     2221 tcctctacaa tttcagtgca gagttcgata cattcgtcac atatatatac accaggtcca
     2281 gctacaagct tacgaacctg atcttgtgtt tttccacaga acgagcattt taattgtcct
     2341 ttttcctcgt taaatttaaa cattctttca ccccttaatc ttgtctcact ttttctttta
     2401 ccggcagagc aaaagaaaat gattcttgaa acgaacgagt atgtattgca ttttaccata
     2461 ctttccaaaa agacggtaac aatgtgtttc tgacttgcac attctatatg tatgacaaaa
     2521 aacagccctg cattaactat attgccccaa gaaaaagaga taactcataa ttgtacaaaa
     2581 caaggcacga atgattcgcg ccctgtttta ttagtactat tattatgcac catattaacg
     2641 gttttctaca agaaaatcaa ttgctttgcg aacttttaaa tcttctttca tcgcgtcagt
     2701 agaaccgatg gcttgtttaa tattttcaac aggcatgttg tatgcttcag ccattttagt
     2761 aagctcagca tcaacttcct catctgatac ttcaaggttt tccgctttcg caatcgcctc
     2821 aagagtcagg ttagatttta cgcgtttttc agcatcttct ttcatttgct ctttaagcgc
     2881 agcttcatct tgacctgaga attgagtgta aagctcaagg ttcatgcctt gcatttgcag
     2941 acgctgttcg aattctttca gcatgcggtc aagctcagtg tcgaccattg cttgcggaac
     3001 atcgatttca gcattttcag aagctttcag aacaagctct tcacgcaatt tagcgtcagc
     3061 ttcgttttct tttgcttctt ctaaacgttt cttagttttt tcagttaatt cagcgagtgt
     3121 ttccacttct tcatcgatat cttttgcgaa ttcatcgtca agctcaggaa gctctttcgc
     3181 tttgatttcg tgaattttca ctttgaacac agctggtttg cctgcaagat cttcagcgtg
     3241 gtactcctca gggaatgtca cttcaacatc cttctcagca cctgcttcaa ggccaactaa
     3301 ttgatcttcg aagccaggga tgaatgaacc agaacctact tctagagagt agttttcagc
     3361 ttttccgcct tcgaatgctt cgccgtcaac gaatccttcg aaatcaagaa caactgtgtt
     3421 tccttcttca acagcgcctt cttcttttac aacaagctca gcttgacgct cttgaagcgc
     3481 ttttagttcg ttttgaacat cttcgtcagt tacagttgtg tcgtcttttt caatgcctaa
     3541 gcctttgtag tcgccaagct tcacttcagg ttttactgtt actttcgcag tgaagattaa
     3601 gctttcgcct ttttcgattt tttcaacatc gatttcagga cggtctacag gctcgattcc
     3661 agcttcttca accgctttag ggtattctac aggaagaaga atatccaaag catcttggta
     3721 aagagcttct acgccaaagc gctgttcgaa taatccgcga ggaattttac ctttacggaa
     3781 tccaggaatt gaaacttgtt ttactacttt tttaaatgca tcatcaagtg ctgttttaaa
     3841 cgtttcagca tcaacttcaa ccgttaaaac gccttcgttg ccttcttgtt tttcccattt
     3901 tacagacatg tgtttccctc caaaaatcta ttcaggttgt ctcggtcttc cattctaaag
     3961 caatcatacg gcttcgtcca acaaaaacaa agctgccaaa gatcagaatc attatgtata
     4021 gatattaata atgaactgca aagcctgtcc aaccgtattt cttataaccc gttatacaca
     4081 aatacaacca ctatattata acataacaca tagcgctttc aactatatgg cgcgatttac
     4141 aaataagaaa tttcttcaat atcttttaac attgtgcaag cttcatcgag ttctctgtcg
     4201 gtaaattcat acatcatatg aagttcttcg ctttcaattt caatcccgtg catctcgtaa
     4261 ccgactttat gaagggcagc cgcccaaagg tcagccgaca gcaatttcgg ctggaacgga
     4321 tataaaacgt acaaatgtct tctccacaat tcctctactg ctgcatataa ggttggattt
     4381 tcatttccaa gtgtctcatc cagcaccctg agaacacggt gcagaatcgg cgcggcatca
     4441 ggcggaacaa tctcagacgg ttcaattgtc aacgactcgc caaatttact aatgtgtaca
     4501 ggcttactgt actcatgctc agccaacagc atgacaatca tcgttttgat aatcggatgg
     4561 gctgaggggt cttggaggat tgttttgagc aatcctgtat actttgctac gttacggtct
     4621 tttaaggaat gaatgagatt catttgctcc tcagggcttg ccagcacttt ctcggtgtca
     4681 attgtatcct catattcttc ggcccaagcc tcgtcctcac gatccggatc ggtcattttc
     4741 cggctgaaat ccagcagctt ataaaattgc tcggcgcttt ctgccggcag ctgattttct
     4801 tccaaaacgg cttcaatggt gcttttgact tcctcgtatt ttttgagctg aattaagatg
     4861 gtcatgtaca cctgcaaaac cgtaaaataa tggccataac cttctttgag catcttctcg
     4921 cacacgcttt ttgcctcttc caactcgccc agctctaaaa agcagatggc catccctaag
     4981 tgaagatcgg cttcagtatc atcatatttc atcgcttctg aaaacagttc gagcgcttct
     5041 tgatactttt tttcctttag tgatgacatc cctttttcca caaggcggtc tttcagatga
     5101 ggaaaaggaa taatttttgc gttcttcttg tcatgcgtca tacctatatt cctttcaggc
     5161 atttattttg ttcaagtgta tcaacacctg tgaacaaaaa caagaaatga aaggtttcac
     5221 caggcaaaaa aagccgccgg acaaataccg gccgcttttt cagtcttgaa gccaagagct
     5281 tctttgtgat tcaaattgct tgatttcatc ttccagcagc agcgttaatg aaatttcatc
     5341 atatccgttg atcagcatct ctttccaatg cgagtcaact tcaaatgaaa tttgattgcc
     5401 ttcactgtca tgaatcagct gattttcaag gtcaacagtc atttgcaatg acttgttttc
     5461 atactggccg acaagctgtt tccaattgtc atatggcatg cggatcggaa gcatgccgtt
     5521 tttaaagcag ttctgatgaa aaatatcagc aaatgacggc gcaatgataa ttttaaaccc
     5581 ataatcatca agtgcccacg gagcgtgttc acgcgatgac ccgcagccga agttttctcc
     5641 tgctattaaa atggaagctc cttgataaac aggctggttt aattcaaatt cagggttcgg
     5701 ttcaccattc gcatcatatc tccagtcaaa gaatgcaaaa cgcccgtagc ctgttctttc
     5761 aatcctcttc aaaaattgct taggaataat ctggtctgta tccacattga tccgatttaa
     5821 tacggccgct ttccccgtat gtgatttcaa aggttccatc tcgcgcactc cttacacaac
     5881 tgttttttcc tgataaaact ttctgacatc aacgaagtgt ccgtgaatgg cagccatcgc
     5941 agccattgcc gggctgacga gatgtgttct tgcacctttt ccttgtctgc cctcgaagtt
     6001 gcggttagag gttgatgcac agcgctctcc ctcaggaaca acatcattat tcatactcaa
     6061 acacatgctg cagcctgact ctctccattc aaatccagct tccaagaaaa tctggtcaag
     6121 cccttctttt tcagcctgaa gcttcacgct ttgggatccg ggcaccacga tggcccttac
     6181 gctgtcagct accttcttcc ctttgatcat gtcagcagcc tgtcgaaggt cagtcatgcg
     6241 ggaatttgtg caggaaccga taaatacgtg ctccacttta atgtcttcaa ttttttggtg
     6301 aggagtcaat cccatatatt cataagcacg aatcgcttct tttttatcgt cttctgcaga
     6361 aaagctttcc ggcgcaggaa cttcagaatc gacaggaaga accattcccg ggttaatgcc
     6421 ccatgtcacc ataggggaaa ttttgttgcc gtcaaggacg atagatttat cataaacagc
     6481 gcccgggtct gtgcgcagcg ccttccattc ctctacggcc ttgtcaaatt cttcgccttt
     6541 tggcgtgtac ttgcgatttt tgcaatattc aaacgtcacc tcgtcaggtg caatcaaacc
     6601 tgctcttgct cctgcttcaa ttgacatgtt acaaacagtc attcgttcat ccatcgtcat
     6661 atttctgaat acttccccag tgtattcaat gacgtagcct gtgccgaatt tcacaccgta
     6721 tttgccgatg acagcaagga tgacatcctt tgccgttacc cctttttgaa gcgttccatc
     6781 tacgcgcact tcaagtgttt ttggacgctg ctgccaaagt gtctgtgtgg aaaggacatg
     6841 ttcgacttca ctcgtcccga ttccaaatgc aagagcgccg aaagcgccat gtgttgatgt
     6901 atgactgtca ccgcacacaa tcgttttccc tggaagcgtt aagcccagtt cagggccgac
     6961 gacatggaca atcccttgat ccacgctgtg aagatcggca aggcgcacgc caaattcctc
     7021 acagtttctt tcaagcgccg ttacctggcg tttcgcaact tcatccttta tctcaaaacg
     7081 attgacagtc gggatgttgt ggtccattgt cgcaaatgtg ttttggggtc ttctgacctt
     7141 tcttcccttt tgtctcaagc cttcaaatgc ctgaggagac gtcacctcat gaatgaggtg
     7201 caaatcaata tagagaagat ccggctttcc ctcaccatgt tttacaatat gctgatccca
     7261 aatcttttcg atgattgttc gaggcatcat cttttatttc ctccctctac ctagagctaa
     7321 gaccgcttaa cgtaagctgt cacacattag aaattgtatt ttcactcatg attgctgcct
     7381 taacttcctc tgtaatggcc tgagtgctgc tgaactcttc accccgtgcc aagtctcttg
     7441 ttctttttcc ggaagccaag actttgttta ccgcatcttc tacagctttc gcttcctctt
     7501 caagcccgaa agatgttctc aaaagcattg ccgctgacaa tatggctgcg aacggatttg
     7561 ccatcccttt accagcaata tcaggcgcgg agccatgaac aggttcaaac agatgaagac
     7621 cagagcttga taggctggct gacgggagca ttccgagcga gcctgtaagc atggacgctt
     7681 catcgcttaa aatatcaccg aacatatttt cagtcaccac gacatcaaat tgattcggtg
     7741 cataaattag ctgcatggcc gcgttatcca caagcatgtg ctcaagcttc acatcaggaa
     7801 actcttgtgc aacgtcctca gccacttcac gccacagccg gcttgattca agaacattcg
     7861 ctttatctac agaggtcact ttgccttttc tggctgccgc cattttaaag ccctctctga
     7921 tcactcgttc aatttccgtt cgcttataaa acagtgtatc tactgcttcc tgctcacctt
     7981 cagtgtttac ataacgtttg ctcggctggc cgaaatacaa gccgcctgtg agctcacgaa
     8041 cgataacgaa atcaacatta tctatatatt cttttttcaa aggcgaagcg tcagaaaggc
     8101 tttcaaatac cttcacaggc cgcaaattcg caaacaaatc aagctgtttt ctgatgctga
     8161 gcagcccttt ttccggtctc agttccgaag gattttgatc ccatttcggt ccgccaacag
     8221 caccaagcaa tatcgcgtct gcatttttac aagcagcaac ggtttcctcc gggagggggt
     8281 tatgatgttc atcaatagcc gcccctccaa tcaggccata ttcaaattca aattcatggt
     8341 taaagcgttc ggcaacactt ttcagtacgt ctgtcgctga ttctaatact tcagggccga
     8401 tcccgtctcc gggcaataga gcaatacgtt tcttcaagtt aaccgttctc ctttctttta
     8461 tgatccgaca gctgtgtggt ttttcaaccc actcatattc gactggaaaa ccaattgacg
     8521 gtttactgcg ttcaaataag ctttcgctga tgcttctaat acgtcttgcg ctatgccccg
     8581 ccctgctgat tcttttccat tcaccaaaac tcttacatac acctgggcaa atgcatcttc
     8641 gccttttctg ttagactgga tgcggtagtc taagagctcc acgtccttat cgatgcagcg
     8701 ctcaagcgta ttgtagattg cttccacgct tccagctcca gttgcagctt cctgaataag
     8761 ctctgcgttt tcttgatttt tcaacgaaag agtagccgta gggacctgac ttgttccgta
     8821 atgtacttgc agagaaagaa attcataccc aatcttgcga tctgttactt tttcttctaa
     8881 aataagagaa acaagatcct catcagtgat ttcttttttc ttctcagtca actctttgaa
     8941 catcgtaaag aatttattaa tctcttcact gtcaaattgg aatcctaaag cagtcagccg
     9001 atctttaaat gcgtggcgtc cggaatgttt acctagaaca agcgcatctg cggttacacc
     9061 gacaagctcc ggtgaaataa tttcataagt cgatttttct tttaaaaagc cgtcctgatg
     9121 gatgcctgat tcatgagcaa atgcattatc tccaacaacc gctttgttgc gcgggacagc
     9181 catgcctgtc agtttgctta ctaaatcact tgttctctta atctcgttca gtgtaatgcc
     9241 tgtttcgact tggtagaaat cttttctggt atggagggct acggcaattt cctctaatgc
     9301 cgcgtttccg gctctttcac cgatcccgtt cacagcgcat tcgatttgat cagcgccgtt
     9361 ttcaatcgca gcaagagagt ttgcgactgc cattcctaaa tcatcatgac agtgggctga
     9421 aagctttgct ttgtgaatgt tcggaacgtt ttccttcata tatctaaaga tatttccgta
     9481 ttccgccgga gccaggtagc cgacagtgtc cggaagattg ataacactgg cgcctgcgtc
     9541 aatcactttt tcgacgattt ctgctagaaa cggcagttca gtgcggcagg catcttcagc
     9601 tgaccattgc acaatcggaa aacgttcttt tgcgtatctc accatttcaa ccgctctttc
     9661 aatgacttgc tcacgtgtca ttttcagctt gtgcttcaaa tgaatgtccg atgtggcgat
     9721 aaatacatga attcttggtt gagcgccatc ctttaacgct tcccaagcag catcaatatc
     9781 accttttaca caacgggcca gaccagttac tgaacaaatt ttaatggttc ttgcgatttc
     9841 ctgaacagct aaaaagtcac ctcgggacga agcgggaaat cccgcttcaa tgatatctgc
     9901 cccgagtctt tcgagctgct tagctatggc aagtttctcc tgtgtattca agttcactcc
     9961 aggggactgt tcaccatcac gaagcgtcgt atcgaaaaaa ttaattttgc gcaacggaga
    10021 ccaccgcttc cttcttcttg ccttgtttca caaacggcat catttcacga agctttcttc
    10081 ccactacttc gatttgatgt tcgttctcgc ttgcattgat agcgttgaaa cgaggacggt
    10141 ttacttggtt ttcgacgatc cactcttttg cgaatgtacc gttttggata tcttttaata
    10201 cttctttcat agattctttt actttagcgt ccacaacgcg aggacctgat acgaaatctc
    10261 cccactgtgc tgtgtcagag attgaatatc tcattcctgc aagtccttct tcgtacataa
    10321 ggtctacgat taatttcagc tcatgaaggc actcgaagta tgcaagttca ggctgataac
    10381 ctgcttcagt taatgtttca aatccggctt tgacaagcgc gcttaatccg ccgcaaagaa
    10441 ctgcttgctc accgaacaaa tctgtttctg tttcttcttt aaatgtcgtt tctaatacgc
    10501 ccgctcttgc gccgccgatt ccttttgcat atgcgagggc tttgtctctt gcttctccag
    10561 tcacatcttg atagattgcg aacaatgcag gtacgccagc tccttgctca tatgttcttc
    10621 ttaccaagtg tcccggtcct ttaggcgcca ctaagaatac atctacatcc gccggaggaa
    10681 caatttgatg gaaatgaacg ttaaatccat gagcaaatac taatgatttt cctgctgtca
    10741 attcatcttt gatttcagct tcgtaaactt tttgctgctg ctcatccgga agcagaacca
    10801 tgatgatttc ggcttgggct gccgcttctt ttactgaaaa tactttatgt ccgtcttctt
    10861 gggcttgagt gaaagatttt ccttgtctaa caccgacgat cacgtctact ccgctttctt
    10921 taaggttcag ggcatgtgcg tggccttgcg aaccgtaccc gataaccgct actgtttttc
    10981 cagccaatac gttctctttg atatcaccgt tataatatac ttttaccatt ttaatctctc
    11041 ccttgttatg ttttatacaa tagatattgt tttattggat gacgcctttt gctgggttcc
    11101 cctcgcaaaa gccgttgtac ctgttctcgc gatttcttta atgccataag gttttaataa
    11161 ctcaataagc gcttcaattt tgttagattc acccgtcacc tgaacaacga tgctgtctct
    11221 gctgacatca acgacagagg ctctaaacgg ttctatgatt ccattaatct ctgttctcgt
    11281 tgaaggtgcg gagacaacct tgattaaggc cagctccctc tggacaatcg attgatttgt
    11341 gatgtctgtg actttcagca catcaatctg tttgttgagc tgtttcgtta actgttcaac
    11401 atcattttca ccttcaacat gaacgacgaa ggtgattctg gaaacgccgg ctgtttctgt
    11461 gtgtccaact gtaatgcttt caatgttgta atgccttttt gtgaatagac cggtgatccg
    11521 gtttaacacc ccggagcggt tcaccacagt caatgtgata attcttttca aggtttcacc
    11581 cccaccattt catgcagccc tttccccgga gccaccatcg ggaatacttt ttcttcgctg
    11641 gcaacccgca cgtcaatgac aacaggttct cttgatgtta atgcctcttc cagcttttcc
    11701 tttgcttccg cttctgatga aattctgatg cctttaatgc cgtatgcttc ggacaatttg
    11761 acgaagtcag gctgagaagc gaatttagat tctgaataac gttcttcata gaaaatttcc
    11821 tgccactgtc tgaccattcc gagacaagcg ttatttaaaa tcactacctt gaccggaaga
    11881 tttaattcgc gaataacatc gagttcttga agcgtcattt ggaatccgcc gtctccgaca
    11941 accgcgacaa cagtagcatc tttttcggcc agctgtgcgc cgatcgccgc cggaagaccg
    12001 aatcccatcg ttccaagtcc gcctgacgtg acccatttat ctgctttttg gaacggataa
    12061 aattgcgctg accacatttg atgctggcct acatctgttg cgacaatggc ctctcctttt
    12121 gtaaattgat gaatatattc aatcaatttc tgaggtttaa aaccttcttc ttcattatct
    12181 acataccaga gcggatactc ttctttccat tctgcgagct gttttttcca ttcgcttgaa
    12241 tcgctttgtt tgccgtcttg tttgatcagc tcctgcagga caattttgct gtctccgact
    12301 acaggaatct gtgttttcat gatttttccg atttcagctg gatcaatatc gatgtgggct
    12361 atctttgcgt ttctggcaaa gtgtttcagg tttcctgtga cacggtcatc aaaacgggcg
    12421 ccgatactga ttaatagatc acattcatga agagccatat tggctgtata agtaccgtgc
    12481 attcccgcca tccctaggaa aagcggatgg tcagccggga agcctccgag ccccaaaagg
    12541 gtgtgtgcca cagggatttg ctgctgttca gcataatttt ttaattcttc tgacgctttt
    12601 ccgtgcagta cgcccgcacc cgccaggatc accggttttt tcgcactgct cacggcttcc
    12661 acaagcttgc ggatctgcaa ataattcggc tctgttgtcg gctggtatcc cgggagattc
    12721 atctcatgat cgtagctgaa ttctccttca attgttgcta catctttcgg aatatcaatc
    12781 aatacaggtc cgggtcttcc agttgttgca atatggaacg cttctttaat gatgcgcggc
    12841 agatcttccg gctggcgaac ctggtagctg tgttttgtta ctggcatcgt aatccctaaa
    12901 atgtctgctt cctgaaatgc atcgctcccg attacagagg ttgctacctg ccctgtaaag
    12961 acaactaacg gcaatgaatc aatcatggca tcagcaaggc ctgtaacaag gtttgtcgct
    13021 cccggccctg acgtggcaat gacgacaccc ggttttccgg agacccttgc gtatccctcc
    13081 gctgcatgaa ttgctccttg ttcgtgacgg ggaaggatat gtaccaaccc tgaattgtat
    13141 agcttatcgt aaatcggaag cacagcccca cccggataac cgaagatcat ttctactttc
    13201 tcttttttta atgattcaat cagcattaat gctccgctca tcgtctgtgt acatttggca
    13261 gatgctgaat ccacctgtac attagtcccc attttagttc ctccttttgg attttcatcc
    13321 tttaaagatc atcttttcat tagctagaca gctgattatt caataaaaaa agcccttccg
    13381 cccacaatca gccgcgcagt aactgcgata gctaaaaggg gcgaaaaggc ttttctttcc
    13441 gcggtaccac ccttgtttac ggccttagtc ggccgtctca tggatatttc tatccgcttt
    13501 agtaacgagt gaatcaagtt cacccggcca agtcctactg tcatttcaga ctggcactct
    13561 gaggcgagtt caccttgtaa agcttcgccg gttctcagct aacccggttc tctgtggaaa
    13621 gctttttcaa ggctacttat cctcatctgc gcttttcata ttcagccttc ggaacggctt
    13681 tccagctgtt caagaaggtc gtttgttttt cattttttta gaatcatact gcgatgattt
    13741 tcgcttgtga agcttgcgtt tatcttttgt tgaactcata ttacgccgct ttggacgcag
    13801 tgtcaacagc attttttaaa attattagac aattttgatt aatcaatcta tattgtatac
    13861 gctttcatta ttggtacaaa aggaattgca aatgttaaaa gtttttataa tttttttatt
    13921 aatctatcaa gaatacacca gaattattta attttatata aacatgtaag attttataac
    13981 acgctatggt t
//
