# emapper version: emapper-2.0.1b-2-g816e190 emapper DB: 2.0 # command: ./emapper.py -i Lactobacillus_helveticus/1.contigAnn/FFN/A00000106.ffn --translate --temp_dir Lactobacillus_helveticus/4.eggNOG_mapper --output_dir Lactobacillus_helveticus/4.eggNOG_mapper --output A00000106 --cpu 36 --keep_mapping_files -m diamond # time: Fri Jun 17 11:41:39 2022 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction taxonomic scope eggNOG OGs best eggNOG OG COG Functional cat. eggNOG free text desc. GHBLAFEN_00001 326425.lhe_1242 9.2e-156 556.2 Lactobacillaceae Bacteria 1TPE1@1239,3F3NJ@33958,4HA65@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family GHBLAFEN_00003 257314.LJ_1459 1.6e-55 222.6 Lactobacillaceae Bacteria 1VNYA@1239,2ER2X@1,33INI@2,3F717@33958,4HSEZ@91061 NA|NA|NA S Domain of unknown function (DUF5067) GHBLAFEN_00004 326425.lhe_1239 5.1e-66 256.9 Firmicutes xkdA Bacteria 1W1K0@1239,COG2856@1,COG2856@2 NA|NA|NA E Zn peptidase GHBLAFEN_00005 326425.lhe_1238 1.6e-36 158.7 Lactobacillaceae ps115 Bacteria 1VEP9@1239,3F871@33958,4HPCR@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins GHBLAFEN_00006 97137.C821_00648 5.2e-16 89.7 Lactobacillaceae Bacteria 1U75S@1239,29PX9@1,30AVM@2,3F90J@33958,4IH0E@91061 NA|NA|NA GHBLAFEN_00007 891391.LAC30SC_06675 1.6e-48 198.4 Lactobacillaceae Bacteria 1U641@1239,2DKNQ@1,30A2R@2,3F6ZG@33958,4IFTI@91061 NA|NA|NA GHBLAFEN_00009 326425.lhe_1234 2e-77 295.0 Lactobacillaceae Bacteria 1VCFK@1239,2DNFZ@1,32XB4@2,3F7GM@33958,4IG23@91061 NA|NA|NA S Siphovirus Gp157 GHBLAFEN_00010 326425.lhe_1233 1.2e-47 195.7 Lactobacillaceae Bacteria 1U82N@1239,29QGU@1,30BG8@2,3FAGE@33958,4II02@91061 NA|NA|NA GHBLAFEN_00011 326425.lhe_1231 4.7e-222 776.9 Lactobacillaceae res Bacteria 1TQ62@1239,3F3YQ@33958,4HAJ1@91061,COG1061@1,COG1061@2 NA|NA|NA L Helicase C-terminal domain protein GHBLAFEN_00013 326425.lhe_1228 3e-56 224.6 Lactobacillaceae Bacteria 1VDGZ@1239,2C0B0@1,32WZE@2,3F79D@33958,4HMDG@91061 NA|NA|NA GHBLAFEN_00014 97137.C821_00664 3.4e-125 454.5 Lactobacillaceae Bacteria 1V4PM@1239,3F3RI@33958,4HHZK@91061,COG3378@1,COG3378@2 NA|NA|NA S Bifunctional DNA primase/polymerase, N-terminal GHBLAFEN_00015 97137.C821_00665 1.7e-182 645.6 Lactobacillaceae Bacteria 1TQNX@1239,3F4EZ@33958,4HCHZ@91061,COG5545@1,COG5545@2 NA|NA|NA S Virulence-associated protein E GHBLAFEN_00016 97137.C821_00673 4.7e-52 210.3 Lactobacillaceae Bacteria 1VA3C@1239,2DJ23@1,32UC6@2,3FBPD@33958,4HM73@91061 NA|NA|NA S VRR-NUC domain GHBLAFEN_00018 326425.lhe_1218 1.3e-08 66.6 Lactobacillaceae Bacteria 1U7RU@1239,29QA6@1,30B9A@2,3FA35@33958,4IHP6@91061 NA|NA|NA GHBLAFEN_00019 12417.Q9T1G2_9CAUD 2.9e-25 121.7 Siphoviridae Viruses 4QFUX@10239,4QMYQ@10699,4QRCD@28883,4QXM6@35237 NA|NA|NA GHBLAFEN_00022 257314.LJ_0306 1.3e-19 103.2 Lactobacillaceae Bacteria 1U854@1239,2AXQ3@1,31PQU@2,3FAJA@33958,4II2M@91061 NA|NA|NA GHBLAFEN_00023 326425.lhe_1216 2.7e-43 181.8 Lactobacillaceae ps333 ko:K07474 ko00000 Bacteria 1VAD9@1239,3F6ZJ@33958,4HXMG@91061,COG3728@1,COG3728@2 NA|NA|NA L Terminase small subunit GHBLAFEN_00024 139871.A9D9R9_9VIRU 2.9e-144 518.5 Viruses Viruses 4QAQF@10239 NA|NA|NA S Terminase-like family GHBLAFEN_00025 257314.LJ_1438 2.8e-127 462.2 Lactobacillaceae Bacteria 1TR67@1239,2DB9U@1,2Z7Z6@2,3F4VA@33958,4HAC8@91061 NA|NA|NA S Phage portal protein, SPP1 Gp6-like GHBLAFEN_00026 891391.LAC30SC_06550 1.8e-114 419.1 Lactobacillaceae Bacteria 1UV98@1239,3FB8J@33958,4HSNW@91061,COG2369@1,COG2369@2 NA|NA|NA S Phage Mu protein F like protein GHBLAFEN_00027 1567453.A0A0A1EN85_9CAUD 1.2e-11 77.0 Siphoviridae Viruses 4QAJ1@10239,4QM2H@10699,4QPE2@28883 NA|NA|NA S aminoacyl-tRNA ligase activity GHBLAFEN_00028 1567453.A0A0A1ELG8_9CAUD 8.2e-64 250.8 Siphoviridae Viruses 4QF51@10239,4QM5F@10699,4QSYD@28883 NA|NA|NA GHBLAFEN_00029 891391.LAC30SC_06530 4.2e-45 187.2 Lactobacillaceae Bacteria 1VN9C@1239,2EKJJ@1,33E9D@2,3F7K9@33958,4HR20@91061 NA|NA|NA S Phage gp6-like head-tail connector protein GHBLAFEN_00030 891391.LAC30SC_06525 3.2e-47 194.1 Lactobacillaceae Bacteria 1VIHK@1239,2E86K@1,332JW@2,3F8A2@33958,4HZJB@91061 NA|NA|NA GHBLAFEN_00031 891391.LAC30SC_06520 1.8e-58 231.9 Lactobacillaceae Bacteria 1VFPA@1239,2CIV5@1,32ZS6@2,3F81G@33958,4HQWN@91061 NA|NA|NA S Bacteriophage HK97-gp10, putative tail-component GHBLAFEN_00032 891391.LAC30SC_06515 2.3e-63 248.1 Lactobacillaceae Bacteria 1VEQW@1239,2DQ37@1,334JI@2,3FBQW@33958,4IS04@91061 NA|NA|NA S Protein of unknown function (DUF3168) GHBLAFEN_00033 891391.LAC30SC_06510 2.5e-93 348.2 Lactobacillaceae Bacteria 1VUVY@1239,2F0XZ@1,33TZM@2,3F76N@33958,4HVU9@91061 NA|NA|NA S Phage tail tube protein GHBLAFEN_00034 891391.LAC30SC_06505 3.5e-59 234.2 Lactobacillaceae Bacteria 1VGCP@1239,2EBTF@1,335T1@2,3F84Y@33958,4HP3P@91061 NA|NA|NA S Phage tail assembly chaperone protein, TAC GHBLAFEN_00035 891391.LAC30SC_06500 8.9e-41 172.6 Lactobacillaceae Bacteria 1VKIN@1239,2EHS8@1,33BHZ@2,3F7N3@33958,4HR6E@91061 NA|NA|NA GHBLAFEN_00036 891391.LAC30SC_06495 4.4e-181 642.1 Lactobacillaceae Z012_10445 Bacteria 1TQ28@1239,3F5K4@33958,4HAFE@91061,COG5283@1,COG5283@2,COG5412@1,COG5412@2 NA|NA|NA D Phage tail tape measure protein GHBLAFEN_00037 891391.LAC30SC_06490 2.8e-152 544.7 Lactobacillaceae Bacteria 1VHE0@1239,3F6A1@33958,4HNTT@91061,COG4722@1,COG4722@2 NA|NA|NA S phage tail GHBLAFEN_00038 891391.LAC30SC_06485 0.0 1283.5 Lactobacillaceae Bacteria 1UM4X@1239,3FBXJ@33958,4ITPI@91061,COG3953@1,COG3953@2,COG4926@1,COG4926@2 NA|NA|NA S Peptidase family M23 GHBLAFEN_00039 891391.LAC30SC_06480 3.1e-21 108.6 Lactobacillaceae Bacteria 1U8IA@1239,2A9D2@1,30YI6@2,3FB0K@33958,4IIGA@91061 NA|NA|NA GHBLAFEN_00040 891391.LAC30SC_06475 1.1e-50 208.8 Lactobacillaceae Bacteria 1UWD6@1239,2EQYH@1,33II5@2,3F8V8@33958,4IGW7@91061 NA|NA|NA S Calcineurin-like phosphoesterase GHBLAFEN_00044 891391.LAC30SC_06470 1.6e-59 235.3 Lactobacillaceae Bacteria 1U6QN@1239,2DKRR@1,30AIG@2,3F8BB@33958,4IGHX@91061 NA|NA|NA GHBLAFEN_00046 891391.LAC30SC_06460 5.4e-19 99.8 Lactobacillaceae Bacteria 1U8FX@1239,29QQA@1,30BQ1@2,3FAXX@33958,4IIDS@91061 NA|NA|NA GHBLAFEN_00047 1423767.BALU01000019_gene1988 4.6e-15 87.8 Lactobacillaceae Bacteria 1U60S@1239,29P23@1,30A09@2,3F6ST@33958,4IFPI@91061 NA|NA|NA GHBLAFEN_00048 1423767.BALU01000006_gene753 6.2e-96 357.5 Lactobacillaceae ko:K07273 ko00000 Bacteria 1TVFG@1239,3F4XM@33958,4I2D1@91061,COG3757@1,COG3757@2 NA|NA|NA M hydrolase, family 25 GHBLAFEN_00049 1423748.BALB01000007_gene843 1.3e-39 168.7 Lactobacillaceae Bacteria 1UI90@1239,2DVJ8@1,33W59@2,3F5JD@33958,4HD3X@91061 NA|NA|NA S Peptidase family M23 GHBLAFEN_00050 326425.lhe_1185 6.8e-153 546.6 Lactobacillaceae yqfL 2.7.11.33,2.7.4.28 ko:K09773 ko00000,ko01000 Bacteria 1TPG0@1239,3F3WK@33958,4HB0Q@91061,COG1806@1,COG1806@2 NA|NA|NA F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation GHBLAFEN_00051 1033837.WANG_0480 2e-22 110.9 Lactobacillaceae rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02970 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEHU@1239,3F81Y@33958,4HNPV@91061,COG0828@1,COG0828@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS21 family GHBLAFEN_00052 326425.lhe_1183 3.2e-69 267.7 Lactobacillaceae yqeY ko:K09117 ko00000 Bacteria 1V6F2@1239,3F6I0@33958,4HIQP@91061,COG1610@1,COG1610@2 NA|NA|NA S YqeY-like protein GHBLAFEN_00053 405566.lhv_1303 8.9e-173 612.8 Lactobacillaceae phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06217 ko00000 Bacteria 1TP35@1239,3F4E7@33958,4HBD5@91061,COG1702@1,COG1702@2 NA|NA|NA T phosphate starvation-inducible protein PhoH GHBLAFEN_00054 1423748.BALB01000007_gene849 3.2e-92 344.4 Lactobacillaceae ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 1V6BU@1239,3F516@33958,4HIIE@91061,COG0319@1,COG0319@2 NA|NA|NA S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA GHBLAFEN_00055 326425.lhe_1180 1.8e-167 595.1 Lactobacillaceae era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 ko:K03595,ko:K06883 ko00000,ko03009,ko03029 Bacteria 1TP3R@1239,3F3WQ@33958,4H9WF@91061,COG1159@1,COG1159@2 NA|NA|NA S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism GHBLAFEN_00056 405566.lhv_1300 1e-136 492.7 Lactobacillaceae recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1UZ19@1239,3F56P@33958,4HAHI@91061,COG1381@1,COG1381@2 NA|NA|NA L Involved in DNA repair and RecF pathway recombination GHBLAFEN_00057 326425.lhe_1178 4.6e-179 633.6 Lactobacillaceae glyQ GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016875,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 ko:K01878,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF1260.b3560,iAF987.Gmet_2942,iJO1366.b3560,iPC815.YPO4072,iY75_1357.Y75_RS19360 Bacteria 1TPW8@1239,3F3T8@33958,4HBCF@91061,COG0752@1,COG0752@2 NA|NA|NA J glycyl-tRNA synthetase alpha subunit GHBLAFEN_00058 326425.lhe_1177 0.0 1325.1 Lactobacillaceae glyS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01879,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iJN678.glyS,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,ic_1306.c4378 Bacteria 1TNZ7@1239,3F4G8@33958,4H9NT@91061,COG0751@1,COG0751@2 NA|NA|NA J Glycyl-tRNA synthetase beta subunit GHBLAFEN_00059 326425.lhe_1176 0.0 1208.0 Lactobacillaceae dnaG ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1TQ0X@1239,3F3N1@33958,4HAG2@91061,COG0358@1,COG0358@2 NA|NA|NA L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication GHBLAFEN_00060 748671.LCRIS_01196 4.6e-197 693.7 Lactobacillaceae sigA GO:0000988,GO:0000990,GO:0001098,GO:0001101,GO:0001108,GO:0001666,GO:0002791,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032879,GO:0032880,GO:0036293,GO:0040007,GO:0042221,GO:0043175,GO:0043254,GO:0044087,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051173,GO:0051223,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070063,GO:0070201,GO:0070482,GO:0071944,GO:0080090,GO:0090087,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:1903530,GO:2000112,GO:2000142,GO:2001141 ko:K03086,ko:K03087 ko02026,ko05111,map02026,map05111 ko00000,ko00001,ko03021 Bacteria 1TPD6@1239,3F4CF@33958,4HB1H@91061,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth GHBLAFEN_00061 326425.lhe_1174 6.8e-124 449.9 Lactobacillaceae Bacteria 1UI90@1239,2DVJ8@1,33W59@2,3F3K4@33958,4HD3X@91061 NA|NA|NA S Peptidase family M23 GHBLAFEN_00062 272621.LBA1193 3.6e-68 264.2 Lactobacillaceae mutT 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1V6PF@1239,3F66W@33958,4HKTF@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain GHBLAFEN_00063 405566.lhv_1293 2.4e-124 451.4 Lactobacillaceae trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 ko00000,ko01000,ko03016 Bacteria 1V3I4@1239,3F4GT@33958,4HHIM@91061,COG2384@1,COG2384@2 NA|NA|NA S SAM-dependent methyltransferase GHBLAFEN_00064 326425.lhe_1171 1e-153 549.3 Lactobacillaceae yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.16 ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ27@1239,3F3ZD@33958,4H9NY@91061,COG0327@1,COG0327@2 NA|NA|NA S Belongs to the GTP cyclohydrolase I type 2 NIF3 family GHBLAFEN_00065 405566.lhv_1291 1.4e-242 845.1 Lactobacillaceae pepT GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0034701,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045148,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.4 ko:K01258 ko00000,ko01000,ko01002 Bacteria 1TP3A@1239,3F45V@33958,4HAZE@91061,COG2195@1,COG2195@2 NA|NA|NA E Cleaves the N-terminal amino acid of tripeptides GHBLAFEN_00066 326425.lhe_1169 3.9e-60 237.3 Lactobacillaceae yvoA_1 ko:K07979 ko00000,ko03000 Bacteria 1VA2B@1239,3F6GC@33958,4HPK4@91061,COG1725@1,COG1725@2 NA|NA|NA K Transcriptional regulator, GntR family GHBLAFEN_00067 326425.lhe_1168 2.8e-123 448.0 Lactobacillaceae skfE ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPUP@1239,3F4GA@33958,4HG6U@91061,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities GHBLAFEN_00068 405566.lhv_1288 1.6e-146 525.4 Lactobacillaceae Bacteria 1U5IX@1239,29NT4@1,309R6@2,3F624@33958,4HZ1H@91061 NA|NA|NA GHBLAFEN_00069 326425.lhe_1166 1.1e-147 529.3 Lactobacillaceae Bacteria 1UG47@1239,29NT4@1,30GID@2,3F5H9@33958,4IF33@91061 NA|NA|NA GHBLAFEN_00070 326425.lhe_1165 1.6e-129 468.8 Lactobacillaceae Bacteria 1U58N@1239,2DKIE@1,309JQ@2,3F55M@33958,4IEZY@91061 NA|NA|NA GHBLAFEN_00071 405566.lhv_1284 4.9e-10 68.9 Lactobacillaceae rarA ko:K07478 ko00000 Bacteria 1TPVV@1239,3F3NB@33958,4HAIS@91061,COG2256@1,COG2256@2 NA|NA|NA L recombination factor protein RarA GHBLAFEN_00072 405566.lhv_1284 9.8e-115 419.5 Lactobacillaceae rarA ko:K07478 ko00000 Bacteria 1TPVV@1239,3F3NB@33958,4HAIS@91061,COG2256@1,COG2256@2 NA|NA|NA L recombination factor protein RarA GHBLAFEN_00073 1423748.BALB01000007_gene870 7.8e-28 129.0 Lactobacillaceae Bacteria 1U6MC@1239,29PI4@1,30AG9@2,3F858@33958,4IGE7@91061 NA|NA|NA GHBLAFEN_00074 405566.lhv_1282 3e-104 384.4 Lactobacillaceae lepB 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1V7H9@1239,3F4SM@33958,4HIQ4@91061,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family GHBLAFEN_00075 405566.lhv_1281 2.7e-140 504.6 Lactobacillaceae Bacteria 1VQQ8@1239,2E39Q@1,32Y99@2,3F4UX@33958,4HRY1@91061 NA|NA|NA GHBLAFEN_00076 326425.lhe_1160 1.8e-176 625.2 Lactobacillaceae Bacteria 1VNCY@1239,2EPHD@1,33H40@2,3F495@33958,4HYY7@91061 NA|NA|NA GHBLAFEN_00077 405566.lhv_1279 2.8e-260 904.0 Lactobacillaceae rsmF 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 1TPGQ@1239,3F492@33958,4HCHQ@91061,COG0144@1,COG0144@2 NA|NA|NA J NOL1 NOP2 sun family protein GHBLAFEN_00078 405566.lhv_1278 1.6e-185 655.2 Lactobacillaceae fni 1.1.1.88,5.3.3.2 ko:K00054,ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123,R02081 RC00004,RC00455,RC00644 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQZ3@1239,3F3UY@33958,4HAMV@91061,COG1304@1,COG1304@2 NA|NA|NA C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) GHBLAFEN_00079 405566.lhv_1277 4.2e-203 713.8 Lactobacillaceae mvaK2 2.7.1.36,2.7.1.43,2.7.4.2 ko:K00869,ko:K00938,ko:K16190 ko00040,ko00053,ko00520,ko00900,ko01100,ko01110,ko01130,ko04146,map00040,map00053,map00520,map00900,map01100,map01110,map01130,map04146 M00014,M00095 R01476,R02245,R03245 RC00002,RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPKP@1239,3F3RZ@33958,4HC93@91061,COG1577@1,COG1577@2 NA|NA|NA I phosphomevalonate kinase GHBLAFEN_00080 326425.lhe_1156 6.4e-179 633.3 Lactobacillaceae mvaD 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQXR@1239,3F4B5@33958,4HAM6@91061,COG3407@1,COG3407@2 NA|NA|NA I diphosphomevalonate decarboxylase GHBLAFEN_00081 326425.lhe_1155 1.1e-167 595.9 Lactobacillaceae mvk 1.1.1.88,2.3.3.10,2.7.1.36 ko:K00054,ko:K00869,ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,ko04146,map00072,map00280,map00650,map00900,map01100,map01110,map01130,map04146 M00088,M00095 R01978,R02081,R02245 RC00002,RC00004,RC00017,RC00503,RC00644 ko00000,ko00001,ko00002,ko01000 Bacteria 1UFCB@1239,3FBNI@33958,4HG49@91061,COG1577@1,COG1577@2 NA|NA|NA I GHMP kinases N terminal domain GHBLAFEN_00082 405566.lhv_1274 0.0 2263.4 Lactobacillaceae rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.3,3.6.4.12 ko:K01153,ko:K16899 ko00000,ko01000,ko02048,ko03400 Bacteria 1TQJW@1239,3FCA9@33958,4HK67@91061,COG3857@1,COG3857@2 NA|NA|NA L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity GHBLAFEN_00083 326425.lhe_1153 0.0 2323.9 Lactobacillaceae addA 3.6.4.12 ko:K16898 ko00000,ko01000,ko03400 Bacteria 1TQ35@1239,3F3Z0@33958,4HA64@91061,COG1074@1,COG1074@2 NA|NA|NA L ATP-dependent helicase nuclease subunit A GHBLAFEN_00084 405566.lhv_1272 0.0 1813.9 Lactobacillaceae dinG GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.6.4.12 ko:K02342,ko:K03722 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TQHQ@1239,3F4KA@33958,4HB2Y@91061,COG0847@1,COG0847@2,COG1199@1,COG1199@2 NA|NA|NA L helicase involved in DNA repair and perhaps also replication GHBLAFEN_00085 326425.lhe_1151 1.1e-89 335.9 Lactobacillaceae ypmB Bacteria 1VA2H@1239,3F4MM@33958,4HNMM@91061,COG5353@1,COG5353@2 NA|NA|NA S Protein conserved in bacteria GHBLAFEN_00086 326425.lhe_1150 1.2e-260 905.2 Lactobacillaceae asnS GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP38@1239,3F4EK@33958,4H9YH@91061,COG0017@1,COG0017@2 NA|NA|NA J Asparaginyl-tRNA synthetase GHBLAFEN_00087 405566.lhv_1269 7.4e-115 419.9 Lactobacillaceae dnaD ko:K02086 ko00000 Bacteria 1V283@1239,3F4FF@33958,4HFP3@91061,COG3935@1,COG3935@2 NA|NA|NA L DnaD domain protein GHBLAFEN_00088 326425.lhe_1148 5.1e-113 413.7 Lactobacillaceae nth 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TRAK@1239,3F42U@33958,4HATD@91061,COG0177@1,COG0177@2 NA|NA|NA L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate GHBLAFEN_00089 326425.lhe_1147 0.0 1331.6 Lactobacillaceae ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366,ko:K12555,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1TPM5@1239,3F424@33958,4H9SA@91061,COG0744@1,COG0744@2 NA|NA|NA M penicillin-binding protein 1A GHBLAFEN_00090 326425.lhe_1146 1.7e-116 425.2 Lactobacillaceae recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03700 ko00000,ko03400 Bacteria 1V3S4@1239,3F4DG@33958,4HGZ7@91061,COG3331@1,COG3331@2 NA|NA|NA L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation GHBLAFEN_00091 405566.lhv_1265 8.6e-107 392.9 Lactobacillaceae ypsA Bacteria 1V6SM@1239,3F4MR@33958,4HJGM@91061,COG4474@1,COG4474@2 NA|NA|NA S Belongs to the UPF0398 family GHBLAFEN_00092 405566.lhv_1264 8e-70 269.6 Lactobacillaceae gpsB ko:K04074 ko00000,ko03036 Bacteria 1VEQ4@1239,3F6VZ@33958,4HNP1@91061,COG3599@1,COG3599@2 NA|NA|NA D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation GHBLAFEN_00093 326425.lhe_1143 2.9e-215 754.2 Lactobacillaceae rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016423,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 ko:K07444,ko:K12297 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1TP0X@1239,3F3NZ@33958,4HBKY@91061,COG0116@1,COG0116@2 NA|NA|NA L Belongs to the methyltransferase superfamily GHBLAFEN_00094 1423748.BALB01000007_gene893 2.4e-132 478.4 Lactobacillaceae cpdA Bacteria 1UQCQ@1239,3F483@33958,4HG8Z@91061,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase GHBLAFEN_00095 1423748.BALB01000007_gene893 2.1e-30 137.9 Lactobacillaceae cpdA Bacteria 1UQCQ@1239,3F483@33958,4HG8Z@91061,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase GHBLAFEN_00096 326425.lhe_1141 0.0 1088.9 Lactobacillaceae fhs 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP6N@1239,3F3U6@33958,4HA2X@91061,COG2759@1,COG2759@2 NA|NA|NA F Belongs to the formate--tetrahydrofolate ligase family GHBLAFEN_00097 405566.lhv_1259 9.5e-80 302.8 Lactobacillaceae lspA 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1VA9R@1239,3F66R@33958,4HIR4@91061,COG0597@1,COG0597@2 NA|NA|NA MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins GHBLAFEN_00098 405566.lhv_1258 5e-157 560.5 Lactobacillaceae rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1TPCM@1239,3F3P6@33958,4HBG2@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil GHBLAFEN_00099 405566.lhv_1257 2.3e-198 698.0 Lactobacillaceae carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383,iYO844.BSU15510 Bacteria 1TQ8N@1239,3F43R@33958,4H9Z0@91061,COG0505@1,COG0505@2 NA|NA|NA F Carbamoyl-phosphate synthetase glutamine chain GHBLAFEN_00100 405566.lhv_1256 0.0 2059.6 Lactobacillaceae carB1 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPID@1239,3F3MD@33958,4HAEY@91061,COG0458@1,COG0458@2 NA|NA|NA F Carbamoyl-phosphate synthase GHBLAFEN_00101 405566.lhv_0475 3.8e-45 187.2 Lactobacillaceae msmR7 Bacteria 1V0Z0@1239,3F53H@33958,4ISD2@91061,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein GHBLAFEN_00102 405566.lhv_0475 9.1e-98 362.8 Lactobacillaceae msmR7 Bacteria 1V0Z0@1239,3F53H@33958,4ISD2@91061,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein GHBLAFEN_00103 748671.LCRIS_01512 2.4e-130 472.2 Lactobacillaceae scrB 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 GH32 Bacteria 1TPAE@1239,3F4UD@33958,4H9Y7@91061,COG1621@1,COG1621@2 NA|NA|NA G invertase GHBLAFEN_00104 748671.LCRIS_01510 8.8e-213 746.1 Lactobacillaceae scrA 2.7.1.208,2.7.1.211 ko:K02749,ko:K02750,ko:K02755,ko:K02756,ko:K02757,ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00268,M00269,M00271 R00811,R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.10,4.A.1.1.16,4.A.1.1.4,4.A.1.1.8,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system GHBLAFEN_00105 748671.LCRIS_01510 2.6e-14 84.0 Lactobacillaceae scrA 2.7.1.208,2.7.1.211 ko:K02749,ko:K02750,ko:K02755,ko:K02756,ko:K02757,ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00268,M00269,M00271 R00811,R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.10,4.A.1.1.16,4.A.1.1.4,4.A.1.1.8,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system GHBLAFEN_00106 257314.LJ_0261 4.7e-97 360.9 Lactobacillaceae rafA GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009987,GO:0010033,GO:0015925,GO:0016043,GO:0016052,GO:0016787,GO:0016798,GO:0022607,GO:0042221,GO:0043933,GO:0044085,GO:0044238,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901545,GO:1901575,GO:1901700 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 Bacteria 1TQF4@1239,3F3RU@33958,4HA5R@91061,COG3345@1,COG3345@2 NA|NA|NA G alpha-galactosidase GHBLAFEN_00107 748671.LCRIS_01509 1.1e-63 249.6 Lactobacillaceae rafA 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 Bacteria 1TQF4@1239,3F3RU@33958,4HA5R@91061,COG3345@1,COG3345@2 NA|NA|NA G alpha-galactosidase GHBLAFEN_00108 405566.lhv_0480 4.6e-188 663.7 Lactobacillaceae manL 2.7.1.191 ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1TQJ4@1239,3FC7R@33958,4HTTA@91061,COG2893@1,COG2893@2,COG3444@1,COG3444@2 NA|NA|NA G PTS system sorbose subfamily IIB component GHBLAFEN_00109 326425.lhe_0492 1.4e-134 485.7 Lactobacillaceae manY ko:K02795,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1TPKK@1239,3F3V5@33958,4H9QI@91061,COG3715@1,COG3715@2 NA|NA|NA G PTS system GHBLAFEN_00110 405566.lhv_0482 7.7e-174 616.3 Lactobacillaceae manN ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1TQA3@1239,3F3KR@33958,4HA3K@91061,COG3716@1,COG3716@2 NA|NA|NA G system, mannose fructose sorbose family IID component GHBLAFEN_00111 326425.lhe_0494 7.6e-64 249.6 Lactobacillaceae manO Bacteria 1V6KV@1239,3FB56@33958,4HX8Z@91061,COG4687@1,COG4687@2 NA|NA|NA S Domain of unknown function (DUF956) GHBLAFEN_00112 326425.lhe_0495 2.4e-104 384.8 Lactobacillaceae Bacteria 1TP77@1239,3F3VP@33958,4HAZB@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator GHBLAFEN_00113 748671.LCRIS_00461 1.2e-22 111.7 Lactobacillaceae Bacteria 1TP77@1239,3F3VP@33958,4HAZB@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator GHBLAFEN_00114 405566.lhv_0486 9.3e-82 309.7 Lactobacillaceae maa Bacteria 1TSQQ@1239,3F73Z@33958,4HJJ7@91061,COG0110@1,COG0110@2 NA|NA|NA S transferase hexapeptide repeat GHBLAFEN_00115 326425.lhe_0497 8.6e-238 829.3 Lactobacillaceae cycA GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease GHBLAFEN_00116 326425.lhe_0498 0.0 1721.8 Lactobacillaceae adhE 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 Bacteria 1TPB4@1239,3F3RN@33958,4HAN8@91061,COG1012@1,COG1012@2,COG1454@1,COG1454@2 NA|NA|NA C belongs to the iron- containing alcohol dehydrogenase family GHBLAFEN_00117 326425.lhe_0499 0.0 1187.9 Lactobacillaceae glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 iNJ661.Rv3436c,iSB619.SA_RS11245,iYO844.BSU01780 Bacteria 1TPGU@1239,3F467@33958,4H9R4@91061,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source GHBLAFEN_00118 326425.lhe_0500 8.8e-47 192.6 Lactobacillaceae Bacteria 1U7QQ@1239,29Q9E@1,30B8I@2,3FA10@33958,4IHN0@91061 NA|NA|NA GHBLAFEN_00119 405566.lhv_0493 1e-102 379.4 Lactobacillaceae yagE Bacteria 1UZNT@1239,3F3SX@33958,4HFMI@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid GHBLAFEN_00120 405566.lhv_0494 1e-72 279.3 Lactobacillaceae Bacteria 1U78P@1239,2DIUI@1,3045J@2,3F94E@33958,4IH3J@91061 NA|NA|NA GHBLAFEN_00121 405566.lhv_0496 2.5e-97 362.5 Lactobacillaceae Bacteria 1U7M2@1239,2BJNP@1,32E07@2,3F9W4@33958,4IHI5@91061 NA|NA|NA S LPXTG cell wall anchor motif GHBLAFEN_00122 326425.lhe_0503 1.4e-223 781.9 Lactobacillaceae ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0409 Bacteria 1TQ22@1239,3F48Z@33958,4HA7K@91061,COG0282@1,COG0282@2 NA|NA|NA F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction GHBLAFEN_00123 326425.lhe_0504 1.3e-136 492.3 Lactobacillaceae 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R03470 RC00938 ko00000,ko00001,ko01000 Bacteria 1TQGP@1239,3FBCM@33958,4HH3D@91061,COG0599@1,COG0599@2 NA|NA|NA S Carboxymuconolactone decarboxylase family GHBLAFEN_00124 326425.lhe_0505 6.4e-37 159.5 Lactobacillaceae Bacteria 1U6B8@1239,29PH8@1,30A80@2,3F7HY@33958,4IG2S@91061 NA|NA|NA GHBLAFEN_00125 326425.lhe_0506 7.7e-73 279.6 Lactobacillaceae apfA 2.7.7.72,3.6.1.61 ko:K00974,ko:K18445 ko00230,ko03013,map00230,map03013 R00184,R09382,R09383,R09384,R09386 RC00002,RC00078 ko00000,ko00001,ko01000,ko03016 Bacteria 1VAMK@1239,3F6NU@33958,4HKCB@91061,COG1051@1,COG1051@2 NA|NA|NA F Nudix hydrolase GHBLAFEN_00126 1423748.BALB01000025_gene1782 0.0 1124.4 Lactobacillaceae pckA 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPXB@1239,3F4N4@33958,4IS6N@91061,COG1866@1,COG1866@2 NA|NA|NA H Phosphoenolpyruvate carboxykinase GHBLAFEN_00127 1423748.BALB01000025_gene1783 3.4e-258 897.5 Lactobacillaceae Bacteria 1V2H3@1239,28PUF@1,2ZCFF@2,3F3KN@33958,4HRKS@91061 NA|NA|NA S TerB-C domain GHBLAFEN_00128 1423748.BALB01000025_gene1785 2.3e-251 874.4 Lactobacillaceae Bacteria 1TQPH@1239,3F54M@33958,4HCUW@91061,COG1135@1,COG1135@2 NA|NA|NA P P-loop Domain of unknown function (DUF2791) GHBLAFEN_00129 1423748.BALB01000025_gene1786 0.0 1497.6 Lactobacillaceae lhr ko:K03724 ko00000,ko01000,ko03400 Bacteria 1UHYQ@1239,3F42E@33958,4HD4E@91061,COG1201@1,COG1201@2 NA|NA|NA L DEAD DEAH box helicase GHBLAFEN_00130 326425.lhe_0509 1.5e-59 235.3 Lactobacillaceae Bacteria 1U61M@1239,29P2Q@1,30A0W@2,3F6U2@33958,4IFQH@91061 NA|NA|NA GHBLAFEN_00131 326425.lhe_0510 2.9e-139 501.1 Lactobacillaceae Bacteria 1TSFT@1239,3F6RG@33958,4HGDA@91061,COG4295@1,COG4295@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2263) GHBLAFEN_00132 1423806.JCM15457_1792 1.1e-14 86.7 Lactobacillaceae Bacteria 1UXP9@1239,3F77K@33958,4IFX8@91061,COG0583@1,COG0583@2 NA|NA|NA K Bacterial regulatory helix-turn-helix protein, lysR family GHBLAFEN_00133 1423806.JCM15457_1794 3e-49 201.4 Lactobacillaceae Bacteria 1TT1Q@1239,3F4IR@33958,4IEVI@91061,COG1053@1,COG1053@2 NA|NA|NA C FAD binding domain GHBLAFEN_00134 1423806.JCM15457_1794 3.1e-26 124.4 Lactobacillaceae Bacteria 1TT1Q@1239,3F4IR@33958,4IEVI@91061,COG1053@1,COG1053@2 NA|NA|NA C FAD binding domain GHBLAFEN_00135 1423806.JCM15457_1794 2.1e-29 134.8 Lactobacillaceae Bacteria 1TT1Q@1239,3F4IR@33958,4IEVI@91061,COG1053@1,COG1053@2 NA|NA|NA C FAD binding domain GHBLAFEN_00136 1423806.JCM15457_1794 4.4e-28 130.6 Lactobacillaceae Bacteria 1TT1Q@1239,3F4IR@33958,4IEVI@91061,COG1053@1,COG1053@2 NA|NA|NA C FAD binding domain GHBLAFEN_00138 326425.lhe_0514 1.9e-127 461.8 Lactobacillaceae XK27_08435 ko:K03710 ko00000,ko03000 Bacteria 1UYYY@1239,3F5F4@33958,4HGI6@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA GHBLAFEN_00139 326425.lhe_0515 3.1e-228 797.3 Lactobacillaceae nagA 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 R02059 RC00166,RC00300 ko00000,ko00001,ko01000 Bacteria 1TPFK@1239,3F40F@33958,4HC6C@91061,COG1820@1,COG1820@2 NA|NA|NA G Belongs to the metallo-dependent hydrolases superfamily. NagA family GHBLAFEN_00140 1545701.LACWKB10_0100 9.9e-61 239.6 Lactobacillaceae rpiR1 Bacteria 1TR5E@1239,3F49F@33958,4HGM0@91061,COG1737@1,COG1737@2 NA|NA|NA K Helix-turn-helix domain, rpiR family GHBLAFEN_00141 326425.lhe_0516 4.1e-71 273.9 Lactobacillaceae Bacteria 1U5KS@1239,2F916@1,309SE@2,3F65Y@33958,4IFBR@91061 NA|NA|NA S Iron-sulphur cluster biosynthesis GHBLAFEN_00142 326425.lhe_0517 7.1e-32 142.5 Lactobacillaceae Bacteria 1U6T5@1239,2C7HR@1,30AK4@2,3F8FZ@33958,4IGKW@91061 NA|NA|NA GHBLAFEN_00143 405566.lhv_0520 2.1e-67 261.5 Lactobacillaceae Bacteria 1U643@1239,2C7EH@1,30A2S@2,3F6ZP@33958,4IFTN@91061 NA|NA|NA GHBLAFEN_00144 1423748.BALB01000016_gene1455 1.5e-95 355.5 Lactobacillaceae pphA 3.1.3.16 ko:K01090,ko:K07313 ko00000,ko01000 Bacteria 1V1HN@1239,3F401@33958,4HF40@91061,COG0639@1,COG0639@2 NA|NA|NA T Calcineurin-like phosphoesterase GHBLAFEN_00145 1423748.BALB01000016_gene1455 1.1e-25 122.1 Lactobacillaceae pphA 3.1.3.16 ko:K01090,ko:K07313 ko00000,ko01000 Bacteria 1V1HN@1239,3F401@33958,4HF40@91061,COG0639@1,COG0639@2 NA|NA|NA T Calcineurin-like phosphoesterase GHBLAFEN_00146 1423748.BALB01000016_gene1454 5.6e-13 79.0 Lactobacillaceae Bacteria 1U6Y4@1239,29PR7@1,30APF@2,3F8PS@33958,4IGSA@91061 NA|NA|NA GHBLAFEN_00147 405566.lhv_0523 3e-45 188.7 Lactobacillaceae Bacteria 1V773@1239,3F3JQ@33958,4HIJG@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain protein GHBLAFEN_00148 1033837.WANG_1162 1.7e-196 691.8 Lactobacillaceae Bacteria 1U570@1239,3F4ZJ@33958,4IEYI@91061,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation GHBLAFEN_00149 326425.lhe_0523 3.4e-111 407.5 Lactobacillaceae Bacteria 1UXY8@1239,3F4JB@33958,4HFD9@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family GHBLAFEN_00150 405566.lhv_0526 3.2e-228 797.3 Lactobacillaceae VY92_08690 5.3.1.32 ko:K11530 ko02024,map02024 ko00000,ko00001,ko01000 Bacteria 1VVR5@1239,3F5NS@33958,4HWFJ@91061,COG0406@1,COG0406@2,COG1359@1,COG1359@2 NA|NA|NA G Antibiotic biosynthesis monooxygenase GHBLAFEN_00151 405566.lhv_0527 3.2e-132 477.6 Lactobacillaceae glpQ1 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1V3W4@1239,3F4E3@33958,4HFNQ@91061,COG0584@1,COG0584@2 NA|NA|NA C glycerophosphoryl diester phosphodiesterase GHBLAFEN_00152 1033837.WANG_1686 2.7e-74 284.6 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TRNY@1239,3F55P@33958,4HBKP@91061,COG0675@1,COG0675@2 NA|NA|NA L transposase, IS605 OrfB family GHBLAFEN_00153 326425.lhe_0590 4.6e-216 756.9 Lactobacillaceae atoB 1.1.1.88,2.3.1.9 ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TP07@1239,3F3Q5@33958,4H9RJ@91061,COG0183@1,COG0183@2 NA|NA|NA I Belongs to the thiolase family GHBLAFEN_00154 405566.lhv_0662 3.3e-217 760.8 Lactobacillaceae mvaA 1.1.1.34,1.1.1.88,2.3.1.9 ko:K00021,ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,ko04152,ko04976,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020,map04152,map04976 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081,R02082 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TPNY@1239,3F3YY@33958,4HBQ3@91061,COG1257@1,COG1257@2 NA|NA|NA C Belongs to the HMG-CoA reductase family GHBLAFEN_00155 405566.lhv_0663 1.8e-215 755.0 Lactobacillaceae mvaS 2.3.3.10 ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR4K@1239,3F425@33958,4HA67@91061,COG3425@1,COG3425@2 NA|NA|NA I Hydroxymethylglutaryl-CoA synthase GHBLAFEN_00156 326425.lhe_0593 4.2e-46 190.3 Lactobacillaceae Bacteria 1U6EZ@1239,29PCT@1,30AB1@2,3F7RU@33958,4IG6T@91061 NA|NA|NA GHBLAFEN_00157 525365.HMPREF0548_0665 7.7e-19 99.4 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TQYU@1239,3F43H@33958,4HC4H@91061,COG1073@1,COG1073@2 NA|NA|NA D Alpha beta GHBLAFEN_00158 1400520.LFAB_09275 3.3e-109 401.0 Lactobacillaceae Bacteria 1TRSF@1239,3F3WY@33958,4HTRR@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family GHBLAFEN_00159 272621.LBA1695 5e-151 540.8 Bacilli asdA 4.1.1.12 ko:K09758 ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230 R00397,R00863 RC00282,RC00399,RC00400 ko00000,ko00001,ko01000 Bacteria 1TQP8@1239,4HECY@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase GHBLAFEN_00160 272621.LBA1696 3.3e-244 850.9 Lactobacillaceae aspT ko:K07085 ko00000 2.A.81 Bacteria 1UGE4@1239,3F5RV@33958,4HTZ2@91061,COG0490@1,COG0490@2,COG2985@1,COG2985@2 NA|NA|NA P Predicted Permease Membrane Region GHBLAFEN_00161 1423758.BN55_05270 2.5e-98 365.2 Lactobacillaceae racD 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 R00491 RC00302 ko00000,ko00001,ko01000 Bacteria 1TQ6M@1239,3FCEP@33958,4HR12@91061,COG1794@1,COG1794@2 NA|NA|NA M Belongs to the aspartate glutamate racemases family GHBLAFEN_00162 1116231.SMA_1824 7.3e-170 603.2 Bacilli wbbI GO:0003674,GO:0003824,GO:0008194,GO:0008378,GO:0008921,GO:0016740,GO:0016757,GO:0016758,GO:0035250 iAF1260.b2034,iBWG_1329.BWG_1824,iECDH10B_1368.ECDH10B_2184,iECDH1ME8569_1439.ECDH1ME8569_1971,iECSF_1327.ECSF_1923,iEcDH1_1363.EcDH1_1623,iJO1366.b2034,iY75_1357.Y75_RS10645 Bacteria 1V8J0@1239,4HITN@91061,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups GHBLAFEN_00163 220668.lp_1176 4e-193 680.6 Lactobacillaceae glf GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 iNJ661.Rv3809c Bacteria 1TQB9@1239,3F52G@33958,4HB5F@91061,COG0562@1,COG0562@2 NA|NA|NA M UDP-galactopyranose mutase GHBLAFEN_00165 1423815.BACR01000056_gene2365 4.4e-16 89.7 Lactobacillaceae Bacteria 1U5AH@1239,2DVX3@1,33XIG@2,3F5D0@33958,4IF1T@91061 NA|NA|NA S Plasmid replication protein GHBLAFEN_00166 891391.LAC30SC_05360 5.5e-53 213.8 Lactobacillaceae Bacteria 1U67S@1239,29P75@1,30A58@2,3F79M@33958,4IFYB@91061 NA|NA|NA GHBLAFEN_00167 405566.lhv_1122 2.3e-78 298.1 Lactobacillaceae Bacteria 1V125@1239,3F5TK@33958,4HFVJ@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain GHBLAFEN_00169 405566.lhv_1123 4.9e-75 287.0 Lactobacillaceae cdd GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009972,GO:0009987,GO:0016020,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019856,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042455,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046108,GO:0046109,GO:0046112,GO:0046131,GO:0046132,GO:0046133,GO:0046134,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0072529,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 2.4.2.4,3.5.4.5 ko:K00758,ko:K01489 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 R01570,R01878,R02484,R02485,R08221,R08222,R08230 RC00063,RC00074,RC00514 ko00000,ko00001,ko01000 Bacteria 1V7IK@1239,3FC88@33958,4HMND@91061,COG0295@1,COG0295@2 NA|NA|NA F Cytidine and deoxycytidylate deaminase zinc-binding region GHBLAFEN_00170 326425.lhe_1021 6.2e-145 520.0 Lactobacillaceae 2.4.2.3 ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01876,R02484,R08229 RC00063 ko00000,ko00001,ko01000 Bacteria 1TQ71@1239,3F3UX@33958,4IRA8@91061,COG2820@1,COG2820@2 NA|NA|NA F Phosphorylase superfamily GHBLAFEN_00171 326425.lhe_1022 4.3e-120 437.2 Lactobacillaceae XK27_07525 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1U7WX@1239,3F4BS@33958,4HHQT@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain GHBLAFEN_00172 326425.lhe_1024 4.8e-63 246.9 Lactobacillaceae Bacteria 1UPY9@1239,2DMQA@1,32SZE@2,3F6TX@33958,4IVD8@91061 NA|NA|NA GHBLAFEN_00173 326425.lhe_1025 7.4e-83 313.2 Lactobacillaceae Bacteria 1U662@1239,29P60@1,30A45@2,3F75G@33958,4IFW2@91061 NA|NA|NA S Domain of unknown function (DUF5067) GHBLAFEN_00174 1033837.WANG_1787 4.3e-88 330.5 Lactobacillaceae luxS GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300 Bacteria 1V1CH@1239,3F4W2@33958,4HFPR@91061,COG1854@1,COG1854@2 NA|NA|NA H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) GHBLAFEN_00175 1033837.WANG_1786 0.0 1531.9 Lactobacillaceae metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131 Bacteria 1TP2H@1239,3F3VW@33958,4H9QC@91061,COG0620@1,COG0620@2 NA|NA|NA E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation GHBLAFEN_00176 1033837.WANG_1785 9.2e-167 592.8 Lactobacillaceae metF GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 ko:K00297,ko:K21010 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,ko02025,map00670,map00720,map01100,map01120,map01200,map01523,map02025 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 iPC815.YPO0117,iSBO_1134.SBO_3961 Bacteria 1TQFE@1239,3F59R@33958,4HBVI@91061,COG0685@1,COG0685@2 NA|NA|NA C Methylenetetrahydrofolate reductase GHBLAFEN_00177 405566.lhv_0310 0.0 1373.6 Lactobacillaceae fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02355 ko00000,ko03012,ko03029 Bacteria 1TPF9@1239,3F3JR@33958,4HAB8@91061,COG0480@1,COG0480@2 NA|NA|NA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome GHBLAFEN_00178 1423748.BALB01000002_gene332 2.3e-81 308.1 Lactobacillaceae rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02992 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1GG@1239,3F3RX@33958,4H9PA@91061,COG0049@1,COG0049@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA GHBLAFEN_00179 405566.lhv_0308 7.8e-70 269.6 Lactobacillaceae rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02950 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1FJ@1239,3F64B@33958,4HFMZ@91061,COG0048@1,COG0048@2 NA|NA|NA J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit GHBLAFEN_00180 326425.lhe_1794 2.3e-122 444.9 Lactobacillaceae pilD 3.4.23.43 ko:K02236,ko:K02506,ko:K02654 M00331,M00429 ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 Bacteria 1W118@1239,3F863@33958,4HZ6B@91061,COG1989@1,COG1989@2 NA|NA|NA NOU Bacterial Peptidase A24 N-terminal domain GHBLAFEN_00181 1423748.BALB01000001_gene70 5.1e-83 313.9 Lactobacillaceae Bacteria 1U5RN@1239,29PIE@1,309UZ@2,3F6DU@33958,4IFFW@91061 NA|NA|NA S Protein of unknown function (DUF3232) GHBLAFEN_00183 1423748.BALB01000001_gene69 1.7e-121 442.2 Lactobacillaceae Bacteria 1U5NC@1239,29NJE@1,309TC@2,3F67W@33958,4IFD2@91061 NA|NA|NA GHBLAFEN_00184 97137.C821_01019 2.7e-17 94.7 Lactobacillaceae Bacteria 1U60J@1239,29NJE@1,30A05@2,3F6SJ@33958,4IFPC@91061 NA|NA|NA K Helix-turn-helix XRE-family like proteins GHBLAFEN_00185 1423748.BALB01000001_gene66 8.2e-143 513.1 Lactobacillaceae Bacteria 1U53D@1239,29NJE@1,309HA@2,3F4BT@33958,4IEUP@91061 NA|NA|NA K Helix-turn-helix XRE-family like proteins GHBLAFEN_00186 405566.lhv_1770 0.0 1495.3 Lactobacillaceae helD 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP39@1239,3F486@33958,4H9Y5@91061,COG3973@1,COG3973@2 NA|NA|NA L DNA helicase GHBLAFEN_00187 326425.lhe_0448 3.8e-125 454.1 Lactobacillaceae XK27_08875 Bacteria 1VW9X@1239,3F60X@33958,4HWF8@91061,COG5549@1,COG5549@2 NA|NA|NA O PFAM peptidase M10A and M12B, matrixin and adamalysin GHBLAFEN_00188 405566.lhv_1772 1.1e-126 459.1 Lactobacillaceae pgm3 Bacteria 1TQWQ@1239,3F524@33958,4HF2N@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family GHBLAFEN_00189 326425.lhe_0046 2.4e-140 505.0 Lactobacillaceae Bacteria 1V192@1239,3F5GG@33958,4IJ3S@91061,COG0846@1,COG0846@2 NA|NA|NA K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form GHBLAFEN_00190 405566.lhv_1224 1.2e-22 112.1 Lactobacillaceae ko:K09705,ko:K12410 ko00000,ko01000 Bacteria 1V192@1239,3F5GG@33958,4IJ3S@91061,COG0846@1,COG0846@2 NA|NA|NA K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form GHBLAFEN_00191 326425.lhe_0048 4.8e-105 387.1 Lactobacillaceae Bacteria 1V6JC@1239,3F58C@33958,4IF0F@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family GHBLAFEN_00192 405566.lhv_0031 1.1e-253 882.1 Lactobacillaceae ko:K07448 ko00000,ko02048 Bacteria 1VI0R@1239,3F8WY@33958,4HPTI@91061,COG1715@1,COG1715@2 NA|NA|NA V Restriction endonuclease GHBLAFEN_00193 525365.HMPREF0548_1318 1.6e-58 232.3 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase GHBLAFEN_00194 1423743.JCM14108_2824 1.1e-167 595.9 Lactobacillaceae Bacteria 1TRSF@1239,3F3WY@33958,4HTRR@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family GHBLAFEN_00195 220668.lp_1196 2.2e-97 361.7 Lactobacillaceae ko:K04763 ko00000,ko03036 Bacteria 1V2RX@1239,3F4SP@33958,4IEJ7@91061,COG0582@1,COG0582@2 NA|NA|NA L Integrase GHBLAFEN_00196 525318.HMPREF0497_1456 1.1e-220 772.3 Lactobacillaceae ko:K07493 ko00000 Bacteria 1TP4C@1239,3F4RA@33958,4HAXJ@91061,COG3328@1,COG3328@2 NA|NA|NA L Transposase GHBLAFEN_00197 326425.lhe_0692 3e-187 661.0 Lactobacillaceae gpsA GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 Bacteria 1TQ5P@1239,3F4C8@33958,4HAXW@91061,COG0240@1,COG0240@2 NA|NA|NA I Glycerol-3-phosphate dehydrogenase GHBLAFEN_00198 1423748.BALB01000001_gene178 9.8e-149 532.7 Lactobacillaceae lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 ko:K03438,ko:K13292 ko00000,ko01000,ko03009 Bacteria 1TPAK@1239,3F42N@33958,4HAT0@91061,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins GHBLAFEN_00199 326425.lhe_0690 2.2e-179 634.8 Lactobacillaceae hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06023 ko00000,ko01000 Bacteria 1TP5Z@1239,3F3Z3@33958,4HAXR@91061,COG1493@1,COG1493@2 NA|NA|NA F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion GHBLAFEN_00200 1033837.WANG_0975 8.4e-23 112.8 Lactobacillaceae Bacteria 1U6A5@1239,29P93@1,30A77@2,3F7F0@33958,4IG1D@91061 NA|NA|NA GHBLAFEN_00201 326425.lhe_0688 3.3e-186 657.5 Lactobacillaceae prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 1TPSB@1239,3F3SN@33958,4H9N2@91061,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA GHBLAFEN_00202 326425.lhe_0687 0.0 1530.8 Lactobacillaceae secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1TPEY@1239,3F4DH@33958,4HA22@91061,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane GHBLAFEN_00203 326425.lhe_0686 9.4e-95 352.8 Lactobacillaceae hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 ko:K05808 ko00000,ko03009 Bacteria 1V1D5@1239,3F40M@33958,4HFX9@91061,COG1544@1,COG1544@2 NA|NA|NA J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase GHBLAFEN_00204 405566.lhv_0718 5.9e-134 483.4 Lactobacillaceae comFC ko:K02242 M00429 ko00000,ko00002,ko02044 Bacteria 1V73S@1239,3F714@33958,4HJ6R@91061,COG1040@1,COG1040@2 NA|NA|NA S Competence protein GHBLAFEN_00205 326425.lhe_0684 4.7e-246 856.7 Lactobacillaceae comFA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K02240 M00429 ko00000,ko00002,ko02044 3.A.11.1 Bacteria 1TPZE@1239,3F3TQ@33958,4HB00@91061,COG4098@1,COG4098@2 NA|NA|NA L Helicase C-terminal domain protein GHBLAFEN_00206 326425.lhe_0683 6.2e-117 426.8 Lactobacillaceae yvyE 3.4.13.9 ko:K01271 ko00000,ko01000,ko01002 Bacteria 1V6MQ@1239,3F3SQ@33958,4HBIT@91061,COG1739@1,COG1739@2 NA|NA|NA S YigZ family GHBLAFEN_00207 405566.lhv_0715 2.4e-209 734.6 Lactobacillaceae tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 ko:K02851 R08856 RC00002 ko00000,ko01000,ko01003,ko01005 Bacteria 1TP9V@1239,3F4JV@33958,4H9KT@91061,COG0472@1,COG0472@2 NA|NA|NA M transferase GHBLAFEN_00208 326425.lhe_0681 6.2e-219 766.9 Lactobacillaceae rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TP48@1239,3F3WX@33958,4HC9J@91061,COG1418@1,COG1418@2 NA|NA|NA S Endoribonuclease that initiates mRNA decay GHBLAFEN_00209 326425.lhe_0680 3.6e-194 684.1 Lactobacillaceae recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 ko:K03553 ko03440,map03440 M00729 ko00000,ko00001,ko00002,ko03400 Bacteria 1TPD5@1239,3F3KU@33958,4HAG5@91061,COG0468@1,COG0468@2 NA|NA|NA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage GHBLAFEN_00210 405566.lhv_0712 1.9e-98 365.2 Lactobacillaceae pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 iSB619.SA_RS06365 Bacteria 1V6PJ@1239,3F4BI@33958,4HCEX@91061,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family GHBLAFEN_00211 326425.lhe_0678 7.2e-134 483.8 Lactobacillaceae ymfM ko:K15539 ko00000 Bacteria 1V1N7@1239,3F3SM@33958,4HKW3@91061,COG1426@1,COG1426@2 NA|NA|NA S Helix-turn-helix domain GHBLAFEN_00212 326425.lhe_0677 5.2e-133 480.3 Lactobacillaceae Bacteria 1V0YW@1239,3FBEA@33958,4ISGK@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase GHBLAFEN_00213 405566.lhv_0709 4.8e-235 820.1 Lactobacillaceae Bacteria 1TP5I@1239,3F4MU@33958,4H9YG@91061,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 GHBLAFEN_00214 405566.lhv_0708 8.7e-226 789.3 Lactobacillaceae 2.7.1.26,2.7.7.2 ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPN6@1239,3F3SA@33958,4H9P5@91061,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 inactive domain protein GHBLAFEN_00215 326425.lhe_0674 0.0 1317.0 Lactobacillaceae ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K03466 ko00000,ko03036 3.A.12 Bacteria 1TPJR@1239,3F3JZ@33958,4H9WA@91061,COG1674@1,COG1674@2 NA|NA|NA D Belongs to the FtsK SpoIIIE SftA family GHBLAFEN_00216 326425.lhe_0673 1.4e-68 265.4 Lactobacillaceae WQ51_03320 Bacteria 1VHA6@1239,3FCDF@33958,4HPTC@91061,COG4835@1,COG4835@2 NA|NA|NA S Protein of unknown function (DUF1149) GHBLAFEN_00217 326425.lhe_0672 1.6e-105 388.7 Lactobacillaceae trmL GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 ko:K03216 ko00000,ko01000,ko03016 Bacteria 1V3GW@1239,3F42Y@33958,4HFNY@91061,COG0219@1,COG0219@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily GHBLAFEN_00218 326425.lhe_0671 1.9e-212 745.0 Lactobacillaceae yubA Bacteria 1TQ84@1239,3F418@33958,4H9SR@91061,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter GHBLAFEN_00219 1423748.BALB01000004_gene626 2.4e-65 254.6 Lactobacillaceae srlB 2.7.1.198 ko:K02781 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 Bacteria 1VGKB@1239,3F8EZ@33958,4HNJN@91061,COG3731@1,COG3731@2 NA|NA|NA G PTS system glucitol/sorbitol-specific IIA component GHBLAFEN_00220 326425.lhe_0669 0.0 1732.6 Lactobacillaceae pacL 3.6.3.8,3.6.3.9 ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 ko00000,ko00001,ko01000,ko04147 3.A.3.1,3.A.3.2 Bacteria 1TPF5@1239,3FC0Z@33958,4HTQ4@91061,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus GHBLAFEN_00221 405566.lhv_0700 5.7e-202 709.9 Lactobacillaceae pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ3J@1239,3F3RC@33958,4HBHB@91061,COG2706@1,COG2706@2 NA|NA|NA G Lactonase, 7-bladed beta-propeller GHBLAFEN_00222 405566.lhv_0699 3.7e-37 160.6 Lactobacillaceae Bacteria 1V6V7@1239,3F417@33958,4HITM@91061,COG0398@1,COG0398@2 NA|NA|NA S SNARE associated Golgi protein GHBLAFEN_00223 326425.lhe_0667 1.3e-29 135.6 Lactobacillaceae Bacteria 1V6V7@1239,3F417@33958,4HITM@91061,COG0398@1,COG0398@2 NA|NA|NA S SNARE associated Golgi protein GHBLAFEN_00224 326425.lhe_0666 0.0 1217.2 Lactobacillaceae mycA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046983,GO:0048037,GO:0050151,GO:0050660,GO:0050662,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901363 4.2.1.53 ko:K10254 ko00000,ko01000 Bacteria 1TQZ6@1239,3F3QX@33958,4HAYH@91061,COG4716@1,COG4716@2 NA|NA|NA S Myosin-crossreactive antigen GHBLAFEN_00225 326425.lhe_0665 5e-170 603.6 Lactobacillaceae rluD 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 Bacteria 1TS1T@1239,3F46Z@33958,4HBRY@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil GHBLAFEN_00226 405566.lhv_0694 2.7e-154 551.2 Lactobacillaceae nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895 Bacteria 1TRB3@1239,3F45D@33958,4HB08@91061,COG0061@1,COG0061@2 NA|NA|NA F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP GHBLAFEN_00227 326425.lhe_0663 2.3e-113 414.8 Lactobacillaceae yjbM 2.7.6.5 ko:K07816 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 1TQ2F@1239,3F452@33958,4HA3Q@91061,COG2357@1,COG2357@2 NA|NA|NA S RelA SpoT domain protein GHBLAFEN_00228 326425.lhe_0662 1.1e-112 412.5 Lactobacillaceae yjbK Bacteria 1TTVM@1239,3F4YS@33958,4I4A3@91061,COG4116@1,COG4116@2 NA|NA|NA S CYTH GHBLAFEN_00229 405566.lhv_0691 2.8e-111 407.9 Lactobacillaceae yjbH GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 Bacteria 1TQ8K@1239,3F6QR@33958,4HAI8@91061,COG2761@1,COG2761@2 NA|NA|NA Q Thioredoxin GHBLAFEN_00230 405566.lhv_0690 1.2e-157 562.4 Lactobacillaceae coiA 3.6.4.12 ko:K03657,ko:K06198 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TRGD@1239,3F4BZ@33958,4HFP5@91061,COG4469@1,COG4469@2 NA|NA|NA S Competence protein GHBLAFEN_00231 326425.lhe_0659 7.6e-132 476.5 Lactobacillaceae mecA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K16511 ko00000 Bacteria 1UZ7D@1239,3F5G4@33958,4HID6@91061,COG4862@1,COG4862@2 NA|NA|NA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis GHBLAFEN_00232 1423748.BALB01000004_gene614 7.9e-67 259.6 Lactobacillaceae spxA 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1V3QC@1239,3F6HJ@33958,4HH0I@91061,COG1393@1,COG1393@2 NA|NA|NA K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress GHBLAFEN_00233 326425.lhe_0657 9.3e-306 1055.4 Lactobacillaceae ptsI GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0008965,GO:0009401,GO:0016740,GO:0016772,GO:0016775,GO:0019197,GO:0032991,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 8.A.7 iB21_1397.B21_02277,iE2348C_1286.E2348C_2602,iEC042_1314.EC042_2625,iECBD_1354.ECBD_1265,iECB_1328.ECB_02316,iECD_1391.ECD_02316,iECH74115_1262.ECH74115_3647,iECIAI1_1343.ECIAI1_2474,iECIAI39_1322.ECIAI39_2562,iECO103_1326.ECO103_2935,iECO111_1330.ECO111_3146,iECO26_1355.ECO26_3469,iECP_1309.ECP_2440,iECSE_1348.ECSE_2707,iECSP_1301.ECSP_3364,iECUMN_1333.ECUMN_2738,iECW_1372.ECW_m2645,iECs_1301.ECs3288,iEKO11_1354.EKO11_1312,iEcE24377_1341.EcE24377A_2703,iEcHS_1320.EcHS_A2551,iEcSMS35_1347.EcSMS35_2571,iEcolC_1368.EcolC_1262,iLF82_1304.LF82_1770,iNRG857_1313.NRG857_12115,iSBO_1134.SBO_2440,iSDY_1059.SDY_2613,iSFV_1184.SFV_2468,iSF_1195.SF2471,iSFxv_1172.SFxv_2720,iSSON_1240.SSON_2505,iS_1188.S2617,iUMNK88_1353.UMNK88_3018,iWFL_1372.ECW_m2645,iZ_1308.Z3682 Bacteria 1TPK8@1239,3F3MS@33958,4H9VD@91061,COG1080@1,COG1080@2 NA|NA|NA G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) GHBLAFEN_00234 1423748.BALB01000004_gene612 8.5e-41 172.6 Lactobacillaceae ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 ko:K11189 ko00000,ko02000 4.A.2.1 Bacteria 1VA0R@1239,3F6XQ@33958,4HKGA@91061,COG1925@1,COG1925@2 NA|NA|NA G phosphocarrier protein HPR GHBLAFEN_00235 1423748.BALB01000004_gene611 2.4e-26 124.0 Lactobacillaceae Bacteria 1U6MM@1239,29PIA@1,30AGF@2,3F85J@33958,4IGEE@91061 NA|NA|NA GHBLAFEN_00236 405566.lhv_0683 0.0 1338.2 Lactobacillaceae clpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03697 ko00000,ko03110 Bacteria 1TPMU@1239,3F3K9@33958,4HA0V@91061,COG0542@1,COG0542@2 NA|NA|NA O Belongs to the ClpA ClpB family GHBLAFEN_00237 1423748.BALB01000004_gene609 3.9e-44 183.7 Lactobacillaceae XK27_09445 Bacteria 1VFRS@1239,2EBZ8@1,335YI@2,3F70G@33958,4HNUK@91061 NA|NA|NA S Domain of unknown function (DUF1827) GHBLAFEN_00238 405566.lhv_0384 3.2e-74 284.3 Lactobacillaceae isp2 Bacteria 1TQ93@1239,3F4RD@33958,4HDNZ@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein GHBLAFEN_00240 326425.lhe_0012 9.2e-175 620.2 Lactobacillaceae ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1UV7Z@1239,3F5Y3@33958,4I2UY@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region GHBLAFEN_00241 585524.HMPREF0493_0173 1e-31 143.3 Bacilli Bacteria 1VSDT@1239,4HUN9@91061,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase GHBLAFEN_00242 405566.lhv_1092 3.7e-48 197.2 Lactobacillaceae Bacteria 1UZVA@1239,3F4KP@33958,4HH09@91061,COG3039@1,COG3039@2 NA|NA|NA L An automated process has identified a potential problem with this gene model GHBLAFEN_00243 1033837.WANG_1111 9.8e-286 988.8 Lactobacillaceae Bacteria 1TSRV@1239,3F46B@33958,4HCIZ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC-type multidrug transport system, ATPase and permease components GHBLAFEN_00244 1033837.WANG_1110 1.1e-287 995.3 Lactobacillaceae Bacteria 1TSRV@1239,3F46B@33958,4HCIZ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC-type multidrug transport system, ATPase and permease components GHBLAFEN_00246 326425.lhe_1907 1.1e-144 519.2 Lactobacillaceae cof Bacteria 1TSGF@1239,3F57T@33958,4HHWU@91061,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase GHBLAFEN_00247 405566.lhv_2082 4.8e-230 803.5 Lactobacillaceae pbuG ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 1TQC6@1239,3F44D@33958,4HANG@91061,COG2252@1,COG2252@2 NA|NA|NA S permease GHBLAFEN_00248 748671.LCRIS_01995 2.1e-172 611.7 Lactobacillaceae ko:K07133 ko00000 Bacteria 1TP7X@1239,3F51K@33958,4HCSJ@91061,COG1373@1,COG1373@2 NA|NA|NA S cog cog1373 GHBLAFEN_00249 405566.lhv_0273 1.3e-159 568.9 Lactobacillaceae Bacteria 1U5TY@1239,2DI1S@1,301QZ@2,3F6I2@33958,4IFHX@91061 NA|NA|NA GHBLAFEN_00250 405566.lhv_0796 5.5e-68 263.5 Lactobacillaceae Bacteria 1TQQ9@1239,3F4M8@33958,4H9KK@91061,COG3666@1,COG3666@2 NA|NA|NA L Transposase GHBLAFEN_00251 272621.LBA0077 2.1e-67 262.3 Lactobacillaceae Bacteria 1TQQ9@1239,3F4M8@33958,4H9KK@91061,COG3666@1,COG3666@2 NA|NA|NA L Transposase GHBLAFEN_00252 1423748.BALB01000010_gene1069 1.2e-25 122.1 Lactobacillaceae Bacteria 1TQQ9@1239,3F4M8@33958,4H9KK@91061,COG3666@1,COG3666@2 NA|NA|NA L Transposase GHBLAFEN_00253 405566.lhv_1918 1.3e-94 352.4 Lactobacillaceae apt 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816,ko:K09685 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko03000,ko04147 Bacteria 1V9BZ@1239,3FBI8@33958,4IQPM@91061,COG0503@1,COG0503@2 NA|NA|NA F Phosphoribosyl transferase domain GHBLAFEN_00254 405566.lhv_1917 2.8e-183 647.9 Lactobacillaceae ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 1UY33@1239,3F41X@33958,4HDN5@91061,COG0659@1,COG0659@2 NA|NA|NA P secondary active sulfate transmembrane transporter activity GHBLAFEN_00255 1302286.BAOT01000085_gene2226 6.8e-195 686.4 Lactobacillaceae Bacteria 1TRSF@1239,3F3YG@33958,4HADR@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family GHBLAFEN_00256 864570.HMPREF9189_1410 2.2e-62 246.1 Bacilli Bacteria 1VH9I@1239,4ITIB@91061,COG1216@1,COG1216@2 NA|NA|NA M Glycosyltransferase like family 2 GHBLAFEN_00257 1033837.WANG_1286 8.8e-156 557.0 Lactobacillaceae Bacteria 1TP7R@1239,3F48Q@33958,4HC84@91061,COG2244@1,COG2244@2 NA|NA|NA S Membrane protein involved in the export of O-antigen and teichoic acid GHBLAFEN_00258 326425.lhe_1466 3.1e-136 491.1 Lactobacillaceae spoU 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 1V3JP@1239,3F3NF@33958,4HCF5@91061,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family GHBLAFEN_00259 326425.lhe_1467 8.4e-44 182.6 Lactobacillaceae acyP GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036 Bacteria 1VEM9@1239,3F81R@33958,4HNN7@91061,COG1254@1,COG1254@2 NA|NA|NA C Belongs to the acylphosphatase family GHBLAFEN_00260 405566.lhv_1585 4.9e-155 553.9 Lactobacillaceae yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 1TSDN@1239,3F3P3@33958,4HCC8@91061,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins GHBLAFEN_00261 326425.lhe_1469 1e-84 319.3 Lactobacillaceae ko:K19055 ko00000,ko01000,ko03016 Bacteria 1V29H@1239,3F6ZD@33958,4HP8F@91061,COG3760@1,COG3760@2 NA|NA|NA S Aminoacyl-tRNA editing domain GHBLAFEN_00262 326425.lhe_0269 4.8e-257 893.3 Lactobacillaceae ykgC GO:0000302,GO:0000305,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0019725,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901530,GO:1901700,GO:1990748 1.16.1.1,1.8.1.7 ko:K00383,ko:K00520,ko:K21739 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1TP1W@1239,3FC6T@33958,4HBZF@91061,COG1249@1,COG1249@2 NA|NA|NA C Pyridine nucleotide-disulfide oxidoreductase GHBLAFEN_00265 1545702.LACWKB8_1419 9.7e-85 320.5 Lactobacillaceae 3.6.3.44 ko:K06148,ko:K11085,ko:K18104 ko01501,ko02010,map01501,map02010 M00700 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 3.A.1,3.A.1.106,3.A.1.117,3.A.1.123 Bacteria 1TSY4@1239,3F9NG@33958,4HAJQ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region GHBLAFEN_00266 326425.lhe_1823 1.2e-16 92.0 Lactobacillaceae Bacteria 1U53C@1239,29NJD@1,309H9@2,3F4BP@33958,4IEUN@91061 NA|NA|NA S Bacteriocin helveticin-J GHBLAFEN_00267 326425.lhe_1823 2.3e-136 491.5 Lactobacillaceae Bacteria 1U53C@1239,29NJD@1,309H9@2,3F4BP@33958,4IEUN@91061 NA|NA|NA S Bacteriocin helveticin-J GHBLAFEN_00268 326425.lhe_1822 4.9e-180 637.1 Lactobacillaceae Bacteria 1U5FB@1239,2DKJ8@1,309P7@2,3F5UP@33958,4IF6X@91061 NA|NA|NA S SLAP domain GHBLAFEN_00269 1033837.WANG_1719 5.2e-41 173.3 Lactobacillaceae Bacteria 1VKZC@1239,2EJES@1,33D5R@2,3F6Y2@33958,4HRGI@91061 NA|NA|NA GHBLAFEN_00270 908339.HMPREF9265_1193 3.6e-26 123.6 Lactobacillaceae Bacteria 1U69C@1239,29P8B@1,30A6E@2,3F7CM@33958,4IG0H@91061 NA|NA|NA GHBLAFEN_00271 1400520.LFAB_17310 0.0 1184.1 Lactobacillaceae traA Bacteria 1VQWC@1239,3F4DP@33958,4HD6B@91061,COG0507@1,COG0507@2 NA|NA|NA L MobA MobL family protein GHBLAFEN_00272 797515.HMPREF9103_01297 5.3e-50 203.4 Lactobacillaceae Bacteria 1U6EB@1239,29PC9@1,30AAH@2,3F7QB@33958,4IG63@91061 NA|NA|NA GHBLAFEN_00273 797515.HMPREF9103_01296 1.1e-102 379.4 Lactobacillaceae Bacteria 1U59R@1239,29NNG@1,309KE@2,3F5AZ@33958,4IF1A@91061 NA|NA|NA GHBLAFEN_00274 1138822.PL11_10165 5.1e-51 206.8 Lactobacillaceae Bacteria 1U5UW@1239,2BZG5@1,309WK@2,3F6IN@33958,4IFIG@91061 NA|NA|NA S Cag pathogenicity island, type IV secretory system GHBLAFEN_00275 908339.HMPREF9265_1407 1.7e-36 158.7 Lactobacillaceae Bacteria 1VVYR@1239,2F48Y@1,33WZQ@2,3F6NH@33958,4HW55@91061 NA|NA|NA GHBLAFEN_00276 1045004.OKIT_0527 9.6e-118 429.5 Bacilli Bacteria 1VEP6@1239,2ECAZ@1,3369B@2,4HQSU@91061 NA|NA|NA GHBLAFEN_00277 1045004.OKIT_0528 0.0 1297.0 Bacilli traE Bacteria 1TPDR@1239,4IQVJ@91061,COG3451@1,COG3451@2 NA|NA|NA U Psort location Cytoplasmic, score GHBLAFEN_00278 220668.45723581 2.9e-220 771.2 Lactobacillaceae polC 2.4.1.129,2.7.7.7,3.4.16.4 ko:K03763,ko:K05366 ko00230,ko00240,ko00550,ko01100,ko01501,ko03030,ko03430,ko03440,map00230,map00240,map00550,map01100,map01501,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko01003,ko01011,ko03032,ko03400 GT51 Bacteria 1V1PS@1239,3F450@33958,4HGKF@91061,COG4499@1,COG4499@2 NA|NA|NA S WXG100 protein secretion system (Wss), protein YukC GHBLAFEN_00279 908339.HMPREF9265_1759 5.4e-201 706.8 Lactobacillaceae ko:K03199 ko03070,map03070 M00333 ko00000,ko00001,ko00002,ko02044 3.A.7 Bacteria 1VW67@1239,3F41W@33958,4HWSY@91061,COG0741@1,COG0741@2,COG0791@1,COG0791@2 NA|NA|NA M CHAP domain GHBLAFEN_00280 908339.HMPREF9265_1758 4.3e-88 330.9 Lactobacillaceae Bacteria 1UFKJ@1239,29UXR@1,30GAH@2,3F46S@33958,4IEU2@91061 NA|NA|NA GHBLAFEN_00281 797515.HMPREF9103_01698 1.8e-81 308.5 Lactobacillaceae Bacteria 1U59I@1239,2AC4N@1,311NX@2,3F59S@33958,4IF0X@91061 NA|NA|NA GHBLAFEN_00282 220668.45723576 1.4e-268 931.8 Lactobacillaceae traK ko:K03205 ko03070,map03070 M00333 ko00000,ko00001,ko00002,ko02044 3.A.7 Bacteria 1TPCF@1239,3F4S3@33958,4H9ZN@91061,COG3505@1,COG3505@2 NA|NA|NA U TraM recognition site of TraD and TraG GHBLAFEN_00283 1138822.PL11_10215 1.2e-62 245.7 Lactobacillaceae Bacteria 1UQAF@1239,2BAF6@1,323VN@2,3F6F2@33958,4IFGF@91061 NA|NA|NA GHBLAFEN_00284 1045004.OKIT_0536 4.6e-149 533.9 Bacilli Bacteria 1VPIB@1239,2EN0Y@1,33FP4@2,4HRWI@91061 NA|NA|NA GHBLAFEN_00285 1423816.BACQ01000038_gene1588 6e-65 253.4 Lactobacillaceae Bacteria 1U5SV@1239,29NXD@1,309VH@2,3F6FI@33958,4IFGT@91061 NA|NA|NA GHBLAFEN_00286 220668.45723572 0.0 1187.2 Lactobacillaceae traI 5.99.1.2 ko:K03169 ko00000,ko01000,ko03032 Bacteria 1TPJD@1239,3F4W6@33958,4HAZV@91061,COG0550@1,COG0550@2 NA|NA|NA L This gene contains a nucleotide ambiguity which may be the result of a sequencing error GHBLAFEN_00287 913848.AELK01000077_gene1657 3.7e-18 97.1 Lactobacillaceae Bacteria 1U69B@1239,29P8A@1,30A6D@2,3F7CJ@33958,4IG0G@91061 NA|NA|NA GHBLAFEN_00288 908339.HMPREF9265_0261 8.5e-191 672.9 Lactobacillaceae Bacteria 1TQN4@1239,3FC8F@33958,4HN8F@91061,COG4227@1,COG4227@2 NA|NA|NA L Psort location Cytoplasmic, score GHBLAFEN_00289 585524.HMPREF0493_1652 2.1e-215 755.4 Lactobacillaceae mod 2.1.1.72 ko:K07316 ko00000,ko01000,ko02048 Bacteria 1TR8A@1239,3F504@33958,4HBP1@91061,COG2189@1,COG2189@2 NA|NA|NA L DNA methylase GHBLAFEN_00290 585524.HMPREF0493_1651 0.0 1548.9 Lactobacillaceae res 3.1.21.5 ko:K01156 ko00000,ko01000,ko02048 Bacteria 1TPRR@1239,3F4QK@33958,4HBNH@91061,COG3587@1,COG3587@2 NA|NA|NA L Type III restriction enzyme, res subunit GHBLAFEN_00294 1232430.CAVG010000148_gene1532 4.4e-93 348.2 Bacilli Bacteria 1VCWV@1239,2C171@1,2Z7ZR@2,4HNFG@91061 NA|NA|NA S SIR2-like domain GHBLAFEN_00295 1297534.CAUJ01000008_gene323 1.3e-207 729.6 Bacilli ko:K06915 ko00000 Bacteria 1V8WX@1239,4IRQ6@91061,COG0433@1,COG0433@2 NA|NA|NA S Domain of unknown function DUF87 GHBLAFEN_00296 944562.HMPREF9102_2131 2.5e-101 374.8 Lactobacillaceae Bacteria 1TQAX@1239,3F429@33958,4HCFF@91061,COG1961@1,COG1961@2 NA|NA|NA L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed GHBLAFEN_00297 257314.LJ_0064 6.2e-99 367.5 Lactobacillaceae Bacteria 1TQ93@1239,3F4RD@33958,4HDNZ@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein GHBLAFEN_00298 1138822.PL11_10145 1.6e-83 316.6 Bacilli ko:K03694,ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 1UZ7G@1239,4HJBJ@91061,COG0542@1,COG0542@2 NA|NA|NA O AAA domain (Cdc48 subfamily) GHBLAFEN_00299 1138822.PL11_10140 3e-44 185.7 Bacilli Bacteria 1V8P5@1239,2B7B4@1,320E7@2,4HSR0@91061 NA|NA|NA GHBLAFEN_00302 1423807.BACO01000083_gene2430 9e-195 686.0 Lactobacillaceae ko:K18481,ko:K18640 M00670 ko00000,ko00002,ko02000,ko04812 3.A.1.27.4,3.A.1.27.5 Bacteria 1V76M@1239,3F499@33958,4IU5K@91061,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein GHBLAFEN_00303 1423807.BACO01000083_gene2429 7.2e-43 179.5 Lactobacillaceae Bacteria 1U6H4@1239,29PER@1,30ACX@2,3F7WY@33958,4IG9F@91061 NA|NA|NA GHBLAFEN_00304 326425.lhe_1911 8.2e-230 802.7 Lactobacillaceae pbuG ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 1TQC6@1239,3F44D@33958,4HANG@91061,COG2252@1,COG2252@2 NA|NA|NA S permease GHBLAFEN_00305 326425.lhe_1910 7.5e-25 119.0 Lactobacillaceae Bacteria 1V05W@1239,3F4R7@33958,4HSX6@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance GHBLAFEN_00306 326425.lhe_1910 3.9e-84 317.4 Lactobacillaceae Bacteria 1V05W@1239,3F4R7@33958,4HSX6@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance GHBLAFEN_00308 326425.lhe_0043 3.9e-30 136.7 Lactobacillaceae WQ51_00220 ko:K07729 ko00000,ko03000 Bacteria 1VERT@1239,3F85E@33958,4HNID@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins GHBLAFEN_00309 326425.lhe_0044 1.2e-112 412.5 Lactobacillaceae ybbL GO:0005575,GO:0005623,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0016020,GO:0019725,GO:0030003,GO:0042592,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071944,GO:0098771 ko:K02065,ko:K02068 ko02010,map02010 M00210,M00211,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1V3DQ@1239,3F4UY@33958,4HHGU@91061,COG4619@1,COG4619@2 NA|NA|NA S ABC transporter, ATP-binding protein GHBLAFEN_00310 326425.lhe_0045 4.3e-130 470.7 Lactobacillaceae ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 ko:K02069 M00211 ko00000,ko00002,ko02000 9.B.25.1 Bacteria 1UY1N@1239,3F4P1@33958,4HDM4@91061,COG0390@1,COG0390@2 NA|NA|NA S Uncharacterised protein family (UPF0014) GHBLAFEN_00311 405566.lhv_0350 6.5e-82 310.1 Lactobacillaceae ko:K07090 ko00000 Bacteria 1VR9G@1239,3F3TR@33958,4HV4W@91061,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein GHBLAFEN_00312 1423748.BALB01000002_gene293 9.8e-14 81.6 Lactobacillaceae 3.1.3.18,3.8.1.2 ko:K01091,ko:K01560,ko:K07025,ko:K11777 ko00361,ko00625,ko00630,ko01100,ko01110,ko01120,ko01130,map00361,map00625,map00630,map01100,map01110,map01120,map01130 R01334,R05287 RC00017,RC00697 ko00000,ko00001,ko01000 Bacteria 1UMZH@1239,3FBY3@33958,4IU43@91061,COG0546@1,COG0546@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase GHBLAFEN_00313 1423748.BALB01000002_gene293 2.4e-66 258.1 Lactobacillaceae 3.1.3.18,3.8.1.2 ko:K01091,ko:K01560,ko:K07025,ko:K11777 ko00361,ko00625,ko00630,ko01100,ko01110,ko01120,ko01130,map00361,map00625,map00630,map01100,map01110,map01120,map01130 R01334,R05287 RC00017,RC00697 ko00000,ko00001,ko01000 Bacteria 1UMZH@1239,3FBY3@33958,4IU43@91061,COG0546@1,COG0546@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase GHBLAFEN_00314 405566.lhv_0348 2e-106 391.7 Lactobacillaceae thiJ 2.7.11.1,3.5.1.124 ko:K03152,ko:K05520,ko:K12132 ko00000,ko01000,ko01001,ko01002 Bacteria 1V3UV@1239,3F3T7@33958,4IQYM@91061,COG0693@1,COG0693@2 NA|NA|NA S DJ-1/PfpI family GHBLAFEN_00315 326425.lhe_1747 5.5e-47 193.7 Lactobacillaceae Bacteria 1VDSW@1239,3F4C0@33958,4HMMJ@91061,COG3152@1,COG3152@2 NA|NA|NA S Protein of unknown function (DUF805) GHBLAFEN_00316 1423767.BALU01000003_gene1008 0.0 1195.6 Lactobacillaceae ko:K09384 ko00000 Bacteria 1TPQU@1239,3F47M@33958,4HBI0@91061,COG3410@1,COG3410@2 NA|NA|NA N Uncharacterized conserved protein (DUF2075) GHBLAFEN_00317 405566.lhv_1874 6.8e-256 889.4 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TQAH@1239,3FBNH@33958,4IRBD@91061,COG0675@1,COG0675@2 NA|NA|NA L Probable transposase GHBLAFEN_00318 405566.lhv_1608 5e-105 387.1 Lactobacillaceae Bacteria 1UZH2@1239,3F4XK@33958,4HW0D@91061,COG2452@1,COG2452@2 NA|NA|NA L Resolvase, N terminal domain GHBLAFEN_00319 1033837.WANG_1078 9.7e-149 533.1 Bacteria ydiM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria COG0738@1,COG0738@2 NA|NA|NA G Major facilitator superfamily GHBLAFEN_00321 1033837.WANG_1076 6.1e-72 276.6 Lactobacillaceae ko:K07171 ko00000,ko01000,ko02048 Bacteria 1U642@1239,3F6ZN@33958,4IFTM@91061,COG2337@1,COG2337@2 NA|NA|NA T PemK-like, MazF-like toxin of type II toxin-antitoxin system GHBLAFEN_00322 405566.lhv_1136 3.6e-285 986.9 Lactobacillaceae lsa ko:K06158,ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000,ko03012 3.A.1.121 Bacteria 1TNYS@1239,3F53D@33958,4HBFK@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter GHBLAFEN_00323 405566.lhv_1485 6.5e-34 149.4 Lactobacillaceae isp2 Bacteria 1TQ93@1239,3F4RD@33958,4HDNZ@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein GHBLAFEN_00324 326425.lhe_0372 2.1e-255 887.9 Lactobacillaceae fruA 2.7.1.202,2.7.1.204 ko:K02768,ko:K02769,ko:K02770,ko:K02806,ko:K20112 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273,M00807 R03232,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.5 Bacteria 1TPKU@1239,3F44C@33958,4H9KR@91061,COG1299@1,COG1299@2,COG1445@1,COG1445@2,COG1762@1,COG1762@2 NA|NA|NA GT Phosphotransferase System GHBLAFEN_00325 405566.lhv_2090 3.2e-242 844.0 Lactobacillaceae amtB ko:K03320 ko00000,ko02000 1.A.11 Bacteria 1TQYG@1239,3F3X1@33958,4HBGK@91061,COG0004@1,COG0004@2 NA|NA|NA P ammonium transporter GHBLAFEN_00326 326425.lhe_1825 1.2e-230 805.4 Lactobacillaceae glyA 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQVM@1239,3F4C1@33958,4HA5K@91061,COG0112@1,COG0112@2 NA|NA|NA E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism GHBLAFEN_00327 748671.LCRIS_00733 6.9e-287 992.6 Lactobacillaceae ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1VT70@1239,3FCAG@33958,4HUMC@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease GHBLAFEN_00328 326425.lhe_0733 1.1e-183 649.0 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TQYU@1239,3F43H@33958,4HC4H@91061,COG1073@1,COG1073@2 NA|NA|NA D Alpha beta GHBLAFEN_00329 1423748.BALB01000001_gene134 1.8e-239 834.7 Lactobacillaceae 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family GHBLAFEN_00330 1423767.BALU01000002_gene1812 2.3e-15 87.0 Lactobacillaceae 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family GHBLAFEN_00331 1423748.BALB01000001_gene134 1.3e-22 111.7 Lactobacillaceae 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family GHBLAFEN_00332 326425.lhe_0731 0.0 1246.5 Lactobacillaceae bglP ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system GHBLAFEN_00333 1423748.BALB01000001_gene136 1.1e-142 512.7 Lactobacillaceae licT ko:K02538,ko:K03488 ko00000,ko03000 Bacteria 1TT5A@1239,3F4SJ@33958,4HC5Y@91061,COG3711@1,COG3711@2 NA|NA|NA K CAT RNA binding domain GHBLAFEN_00334 405566.lhv_0764 3.9e-215 753.8 Lactobacillaceae glxK 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 R08572 RC00002,RC00428 ko00000,ko00001,ko01000 Bacteria 1TPSI@1239,3F3V2@33958,4HA91@91061,COG1929@1,COG1929@2 NA|NA|NA G Belongs to the glycerate kinase type-1 family GHBLAFEN_00335 326425.lhe_0728 9.9e-85 319.3 Lactobacillaceae ptpA 3.1.3.48 ko:K01104,ko:K20945 ko05111,map05111 ko00000,ko00001,ko01000 Bacteria 1V6SG@1239,3F74A@33958,4HIZN@91061,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family GHBLAFEN_00336 405566.lhv_0762 1.8e-117 428.7 Lactobacillaceae Bacteria 1U56K@1239,29NKW@1,309IV@2,3F4Y0@33958,4IEXT@91061 NA|NA|NA GHBLAFEN_00337 326425.lhe_0726 3.8e-148 530.8 Lactobacillaceae Bacteria 1U3W2@1239,3FC85@33958,4HM9S@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase GHBLAFEN_00338 405566.lhv_0760 2.6e-149 534.6 Lactobacillaceae Bacteria 1TR16@1239,3F55S@33958,4HCZ6@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase GHBLAFEN_00339 326425.lhe_0724 3.1e-256 890.6 Lactobacillaceae glmM GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 R02060 RC00408 ko00000,ko00001,ko01000 iSB619.SA_RS11275,iSBO_1134.SBO_3206 Bacteria 1TP1X@1239,3F3W5@33958,4HB16@91061,COG1109@1,COG1109@2 NA|NA|NA G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate GHBLAFEN_00340 405566.lhv_0758 2.4e-170 604.7 Lactobacillaceae ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 Bacteria 1TSIV@1239,3F41C@33958,4HD8Y@91061,COG4856@1,COG4856@2 NA|NA|NA S YbbR-like protein GHBLAFEN_00341 326425.lhe_0722 4.2e-150 537.3 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 ko00000,ko01000 Bacteria 1TPRW@1239,3F4N3@33958,4H9XZ@91061,COG1624@1,COG1624@2 NA|NA|NA S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria GHBLAFEN_00342 326425.lhe_0721 5.6e-208 729.9 Lactobacillaceae potD ko:K11069 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 iSB619.SA_RS05395 Bacteria 1TPY1@1239,3F3W1@33958,4HAET@91061,COG0687@1,COG0687@2 NA|NA|NA P ABC transporter GHBLAFEN_00343 326425.lhe_0720 1.7e-132 478.8 Lactobacillaceae potC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008519,GO:0015075,GO:0015101,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015595,GO:0015606,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072488,GO:0098533,GO:0098655,GO:0098796,GO:0098797,GO:1902047,GO:1902494,GO:1902495,GO:1903711,GO:1904949,GO:1990351 ko:K11070 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 iSBO_1134.SBO_1939 Bacteria 1V0VD@1239,3F3ZN@33958,4H9ZC@91061,COG1177@1,COG1177@2 NA|NA|NA P ABC transporter permease GHBLAFEN_00344 326425.lhe_0719 5.1e-129 467.2 Lactobacillaceae potB ko:K11071 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 Bacteria 1TQ7Z@1239,3F4CM@33958,4HAYS@91061,COG1176@1,COG1176@2 NA|NA|NA P ABC transporter permease GHBLAFEN_00345 326425.lhe_0718 2e-205 721.5 Lactobacillaceae potA 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 iSB619.SA_RS05380 Bacteria 1TP2M@1239,3F40H@33958,4H9MS@91061,COG3842@1,COG3842@2 NA|NA|NA P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system GHBLAFEN_00346 405566.lhv_0752 1.1e-164 585.9 Lactobacillaceae murB 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 Bacteria 1TP3W@1239,3F40T@33958,4HAD8@91061,COG0812@1,COG0812@2 NA|NA|NA M Cell wall formation GHBLAFEN_00347 1423748.BALB01000001_gene151 1.4e-98 365.5 Lactobacillaceae dnaQ 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1V57H@1239,3F42Z@33958,4HI1V@91061,COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III GHBLAFEN_00348 326425.lhe_0715 6.4e-90 336.7 Lactobacillaceae ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.1.221,5.1.1.1 ko:K01775,ko:K06925,ko:K07102 ko00473,ko00520,ko01100,ko01502,map00473,map00520,map01100,map01502 R00401,R08968,R11024 RC00002,RC00078,RC00285 ko00000,ko00001,ko01000,ko01011,ko03016 Bacteria 1V6CV@1239,3F3MR@33958,4HIIF@91061,COG0802@1,COG0802@2 NA|NA|NA O Hydrolase, P-loop family GHBLAFEN_00349 326425.lhe_0714 1.8e-181 641.7 Lactobacillaceae pta 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028,ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 iSB619.SA_RS03155 Bacteria 1TPQ0@1239,3F3MW@33958,4H9VH@91061,COG0280@1,COG0280@2 NA|NA|NA C phosphate acetyltransferase GHBLAFEN_00350 326425.lhe_0713 3.3e-137 494.2 Lactobacillaceae ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPSN@1239,3F3W0@33958,4HBTR@91061,COG0692@1,COG0692@2 NA|NA|NA L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine GHBLAFEN_00351 326425.lhe_0712 4.8e-157 560.5 Lactobacillaceae ycsE Bacteria 1V5FB@1239,3F58Y@33958,4HGY8@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase GHBLAFEN_00352 1423748.BALB01000001_gene156 1.8e-95 355.1 Lactobacillaceae Bacteria 1U5NS@1239,29NVF@1,309TI@2,3F68I@33958,4IFDC@91061 NA|NA|NA GHBLAFEN_00353 1423748.BALB01000001_gene159 1.2e-143 515.8 Lactobacillaceae tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS19265 Bacteria 1TP2F@1239,3F494@33958,4HAPT@91061,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) GHBLAFEN_00354 326425.lhe_0709 9.3e-228 795.8 Lactobacillaceae pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iSB619.SA_RS04145 Bacteria 1TP3H@1239,3F3SC@33958,4H9R3@91061,COG0126@1,COG0126@2 NA|NA|NA F Belongs to the phosphoglycerate kinase family GHBLAFEN_00355 1423748.BALB01000001_gene161 8.4e-190 669.5 Lactobacillaceae gap GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009986,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0022610,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044464,GO:0044650,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:0140030,GO:0140032,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iJR904.b1416,iJR904.b1417 Bacteria 1TNYU@1239,3F3JS@33958,4H9NS@91061,COG0057@1,COG0057@2 NA|NA|NA G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family GHBLAFEN_00356 405566.lhv_0742 1.2e-188 665.6 Lactobacillaceae cggR ko:K05311 ko00000,ko03000 Bacteria 1TP62@1239,3F53Y@33958,4HAE6@91061,COG2390@1,COG2390@2 NA|NA|NA K Putative sugar-binding domain GHBLAFEN_00358 1423748.BALB01000001_gene163 9e-77 292.7 Lactobacillaceae Bacteria 1W1FZ@1239,2FIUN@1,34AK2@2,3F4QI@33958,4HYXZ@91061 NA|NA|NA GHBLAFEN_00359 1423748.BALB01000001_gene163 7.1e-88 330.1 Lactobacillaceae Bacteria 1W1FZ@1239,2FIUN@1,34AK2@2,3F4QI@33958,4HYXZ@91061 NA|NA|NA GHBLAFEN_00360 1423748.BALB01000001_gene163 1.9e-32 144.8 Lactobacillaceae Bacteria 1W1FZ@1239,2FIUN@1,34AK2@2,3F4QI@33958,4HYXZ@91061 NA|NA|NA GHBLAFEN_00361 1423748.BALB01000001_gene164 3.1e-270 937.2 Lactobacillaceae ycaM ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1TRFS@1239,3FCAH@33958,4HBIP@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid GHBLAFEN_00362 1423748.BALB01000001_gene165 1.5e-133 482.3 Lactobacillaceae Bacteria 1UYU8@1239,3F3YK@33958,4HE0K@91061,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase GHBLAFEN_00363 326425.lhe_0702 0.0 1079.3 Lactobacillaceae Bacteria 1W1FZ@1239,2FIUN@1,34AK2@2,3F4QV@33958,4HYXZ@91061 NA|NA|NA S SH3-like domain GHBLAFEN_00364 1423767.BALU01000008_gene600 9.4e-161 572.8 Lactobacillaceae ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1UYSD@1239,3F48U@33958,4IPMN@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease GHBLAFEN_00365 1423748.BALB01000009_gene1033 1.3e-96 359.0 Lactobacillaceae ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1UYSD@1239,3F48U@33958,4IPMN@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease GHBLAFEN_00366 1423748.BALB01000009_gene1032 9.8e-21 105.1 Lactobacillaceae XK26_02160 Bacteria 1TR2Q@1239,3F66T@33958,4HHXT@91061,COG5015@1,COG5015@2 NA|NA|NA C Pyridoxamine 5'-phosphate oxidase GHBLAFEN_00368 349519.LCK_00775 2.3e-58 231.9 Leuconostocaceae Bacteria 1VCNX@1239,4AXNW@81850,4HKR6@91061,COG1302@1,COG1302@2 NA|NA|NA S protein conserved in bacteria GHBLAFEN_00369 203120.LEUM_0863 4.4e-10 70.1 Leuconostocaceae Bacteria 1U3ID@1239,29MM7@1,308IY@2,4AY9X@81850,4IDB7@91061 NA|NA|NA S Small integral membrane protein (DUF2273) GHBLAFEN_00370 203120.LEUM_0862 2.9e-43 181.8 Leuconostocaceae Bacteria 1U9V2@1239,29EVE@1,301T5@2,4AXW4@81850,4ID75@91061 NA|NA|NA GHBLAFEN_00372 326425.lhe_1558 8.8e-142 509.6 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1UZ6K@1239,3F5A4@33958,4HCYU@91061,COG3694@1,COG3694@2 NA|NA|NA S ABC-2 family transporter protein GHBLAFEN_00373 326425.lhe_1559 8.8e-110 403.3 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1VDUN@1239,3F6DQ@33958,4HE8R@91061,COG4587@1,COG4587@2 NA|NA|NA S ABC-2 family transporter protein GHBLAFEN_00374 1122152.AUEI01000013_gene382 9.3e-149 533.1 Lactobacillaceae ldhA 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3FB6E@33958,4HBWS@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family GHBLAFEN_00375 1122152.AUEI01000013_gene383 3.2e-69 268.1 Lactobacillaceae ko:K07088 ko00000 Bacteria 1TQZK@1239,3FCFI@33958,4HAS0@91061,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein GHBLAFEN_00376 326425.lhe_0399 8e-124 449.9 Lactobacillaceae ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1VG0Z@1239,3F50V@33958,4HBE9@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC P60 family protein GHBLAFEN_00377 326425.lhe_0988 2.1e-64 251.5 Lactobacillaceae crcB ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 1U4G6@1239,3F6R4@33958,4IE88@91061,COG0239@1,COG0239@2 NA|NA|NA U Important for reducing fluoride concentration in the cell, thus reducing its toxicity GHBLAFEN_00378 326425.lhe_0989 2.9e-63 247.7 Lactobacillaceae crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 1VM30@1239,3F8A8@33958,4HRC4@91061,COG0239@1,COG0239@2 NA|NA|NA U Important for reducing fluoride concentration in the cell, thus reducing its toxicity GHBLAFEN_00379 1423748.BALB01000009_gene1032 5.5e-29 133.3 Lactobacillaceae XK26_02160 Bacteria 1TR2Q@1239,3F66T@33958,4HHXT@91061,COG5015@1,COG5015@2 NA|NA|NA C Pyridoxamine 5'-phosphate oxidase GHBLAFEN_00380 405566.lhv_1911 4.4e-08 62.8 Lactobacillaceae ropB Bacteria 1VD8E@1239,3F61C@33958,4HMD2@91061,COG1396@1,COG1396@2 NA|NA|NA K Transcriptional regulator GHBLAFEN_00381 405566.lhv_1910 3.8e-183 647.5 Lactobacillaceae ko:K07785 ko02020,map02020 ko00000,ko00001,ko02000 2.A.1.31 Bacteria 1UI8U@1239,3FBSV@33958,4ISG9@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator Superfamily GHBLAFEN_00382 1033837.WANG_1734 1.5e-112 412.5 Lactobacillaceae Bacteria 1V3YR@1239,2BVD0@1,32QT1@2,3F67T@33958,4HK85@91061 NA|NA|NA GHBLAFEN_00383 1423748.BALB01000001_gene109 3.9e-155 554.3 Lactobacillaceae ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1UYQB@1239,3F3NG@33958,4HE3Y@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GHBLAFEN_00384 891391.LAC30SC_03770 1.2e-30 139.0 Lactobacillaceae ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1UYQB@1239,3F3NG@33958,4HE3Y@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GHBLAFEN_00385 326425.lhe_0757 4.6e-196 690.3 Lactobacillaceae ampC Bacteria 1TNZX@1239,3F3WZ@33958,4IPJT@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase GHBLAFEN_00388 405566.lhv_0800 1.8e-248 864.8 Lactobacillaceae murF 6.3.2.10,6.3.2.13 ko:K01928,ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R02788,R04573,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TRG9@1239,3FBS5@33958,4HAMY@91061,COG0770@1,COG0770@2 NA|NA|NA M Domain of unknown function (DUF1727) GHBLAFEN_00389 326425.lhe_0771 2.2e-113 414.8 Lactobacillaceae tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 iAF1260.b1238,iBWG_1329.BWG_1065,iECDH10B_1368.ECDH10B_1298,iECDH1ME8569_1439.ECDH1ME8569_1176,iEcDH1_1363.EcDH1_2411,iJO1366.b1238,iJR904.b1238,iPC815.YPO2176,iY75_1357.Y75_RS06470 Bacteria 1TRVM@1239,3F4UE@33958,4HA4A@91061,COG1435@1,COG1435@2 NA|NA|NA F thymidine kinase GHBLAFEN_00390 326425.lhe_0772 6.9e-182 643.3 Lactobacillaceae prfA ko:K02835 ko00000,ko03012 Bacteria 1TQ7V@1239,3F3Q0@33958,4H9MB@91061,COG0216@1,COG0216@2 NA|NA|NA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA GHBLAFEN_00391 326425.lhe_0773 3.3e-155 554.3 Lactobacillaceae prmB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564 2.1.1.297,2.1.1.298 ko:K02493,ko:K07320 R10806 RC00003,RC03279 ko00000,ko01000,ko03009,ko03012 Bacteria 1TSMA@1239,3F460@33958,4HC6W@91061,COG2890@1,COG2890@2 NA|NA|NA J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif GHBLAFEN_00392 326425.lhe_0774 1.9e-189 668.3 Lactobacillaceae ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87,3.1.3.48 ko:K01104,ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 1TP1I@1239,3F3T1@33958,4HA7W@91061,COG0009@1,COG0009@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine GHBLAFEN_00393 1423748.BALB01000001_gene101 2e-112 411.8 Lactobacillaceae upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000 iSB619.SA_RS11010 Bacteria 1TPMT@1239,3F4M0@33958,4H9Y0@91061,COG0035@1,COG0035@2 NA|NA|NA F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate GHBLAFEN_00394 326425.lhe_0776 3.8e-128 464.2 Lactobacillaceae atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666 Bacteria 1TQIT@1239,3F3RE@33958,4H9NV@91061,COG0356@1,COG0356@2 NA|NA|NA C it plays a direct role in the translocation of protons across the membrane GHBLAFEN_00395 1423748.BALB01000001_gene99 3.5e-27 127.1 Lactobacillaceae atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 1VEHP@1239,3F82A@33958,4HNKQ@91061,COG0636@1,COG0636@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation GHBLAFEN_00396 405566.lhv_0808 7.3e-49 200.3 Lactobacillaceae atpF ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iHN637.CLJU_RS01170,iYO844.BSU36850 Bacteria 1VB85@1239,3F5M8@33958,4HM64@91061,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) GHBLAFEN_00397 405566.lhv_0809 6.8e-93 346.7 Lactobacillaceae atpH GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 1VAG3@1239,3F5TZ@33958,4HKFW@91061,COG0712@1,COG0712@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation GHBLAFEN_00398 405566.lhv_0810 1.1e-281 975.3 Lactobacillaceae atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 Bacteria 1TNZ8@1239,3F3R4@33958,4HAMZ@91061,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit GHBLAFEN_00399 326425.lhe_0781 2.7e-169 601.3 Lactobacillaceae atpG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611,iSB619.SA_RS10970,iYO844.BSU36820 Bacteria 1TPBX@1239,3F40E@33958,4HB0E@91061,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex GHBLAFEN_00400 1033837.WANG_0899 1.3e-233 815.5 Lactobacillaceae atpD 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iSB619.SA_RS10965 Bacteria 1TPGF@1239,3F3TF@33958,4HAT6@91061,COG0055@1,COG0055@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits GHBLAFEN_00401 1033837.WANG_0898 2.2e-52 211.8 Lactobacillaceae atpC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190 Bacteria 1VA89@1239,3F6I6@33958,4HKHS@91061,COG0355@1,COG0355@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane GHBLAFEN_00402 405566.lhv_2402 5.8e-30 136.3 Lactobacillaceae ywzB Bacteria 1U2FQ@1239,3F831@33958,4HNZX@91061,COG4836@1,COG4836@2 NA|NA|NA S Protein of unknown function (DUF1146) GHBLAFEN_00403 1423748.BALB01000001_gene90 3.2e-178 630.9 Lactobacillaceae mbl ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 1TP51@1239,3F463@33958,4HA4S@91061,COG1077@1,COG1077@2 NA|NA|NA D Cell shape determining protein MreB Mrl GHBLAFEN_00404 405566.lhv_2403 2.5e-49 201.1 Lactobacillaceae yidD ko:K08998 ko00000 Bacteria 1VEIG@1239,3F7H1@33958,4HPA3@91061,COG0759@1,COG0759@2 NA|NA|NA S Could be involved in insertion of integral membrane proteins into the membrane GHBLAFEN_00405 272621.LBA0781 2.5e-33 147.5 Lactobacillaceae Bacteria 1U6BQ@1239,29FEW@1,302CK@2,3F7J3@33958,4IG3B@91061 NA|NA|NA S Protein of unknown function (DUF2969) GHBLAFEN_00406 326425.lhe_0788 3.1e-215 754.2 Lactobacillaceae rodA ko:K05837 ko00000,ko03036 Bacteria 1TPGH@1239,3F4J4@33958,4HAV4@91061,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family GHBLAFEN_00407 326425.lhe_0789 4e-78 297.4 Lactobacillaceae usp6 ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1V3NY@1239,3F68T@33958,4HIP3@91061,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein GHBLAFEN_00408 405566.lhv_2404 2.5e-35 154.5 Lactobacillaceae Bacteria 1U6AF@1239,29P9A@1,30A7E@2,3F7FU@33958,4IG1T@91061 NA|NA|NA GHBLAFEN_00409 405566.lhv_0818 8e-241 839.3 Lactobacillaceae rarA ko:K07478 ko00000 Bacteria 1TPVV@1239,3F3WF@33958,4HAIS@91061,COG2256@1,COG2256@2 NA|NA|NA L recombination factor protein RarA GHBLAFEN_00410 326425.lhe_0791 2.7e-82 311.2 Lactobacillaceae yueI Bacteria 1V8ID@1239,3FCEV@33958,4HJTQ@91061,COG5506@1,COG5506@2 NA|NA|NA S Protein of unknown function (DUF1694) GHBLAFEN_00411 326425.lhe_0792 6.8e-110 403.3 Lactobacillaceae rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 ko:K02986 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TR0J@1239,3F3P0@33958,4HAC9@91061,COG0522@1,COG0522@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit GHBLAFEN_00412 326425.lhe_0793 3.2e-282 977.2 Lactobacillaceae ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 ko:K06286,ko:K07158 ko00000,ko03036 Bacteria 1TQR7@1239,3F47K@33958,4HA15@91061,COG4477@1,COG4477@2 NA|NA|NA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization GHBLAFEN_00413 405566.lhv_0822 8.4e-218 762.7 Lactobacillaceae iscS2 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TP21@1239,3F4CD@33958,4HAEE@91061,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class V GHBLAFEN_00414 405566.lhv_0823 1.7e-229 801.6 Lactobacillaceae thiI GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07461 ko00000,ko00001,ko01000,ko03016 iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307 Bacteria 1TPNW@1239,3F3N0@33958,4HAV9@91061,COG0301@1,COG0301@2 NA|NA|NA H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS GHBLAFEN_00415 1423748.BALB01000001_gene78 1.1e-142 512.7 Lactobacillaceae Bacteria 1U6CJ@1239,29NJE@1,30A94@2,3F7KV@33958,4IG48@91061 NA|NA|NA K Helix-turn-helix domain GHBLAFEN_00416 1033837.WANG_0872 2.7e-126 458.0 Lactobacillaceae rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 ko00000,ko01000,ko03009 Bacteria 1TQZ2@1239,3F41G@33958,4H9VU@91061,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family GHBLAFEN_00417 326425.lhe_0802 2.9e-82 311.6 Lactobacillaceae Bacteria 1U53D@1239,29NJE@1,309HA@2,3F4BT@33958,4IEUP@91061 NA|NA|NA K Helix-turn-helix XRE-family like proteins GHBLAFEN_00418 1033837.WANG_0871 6.9e-128 463.4 Lactobacillaceae Bacteria 1U5NC@1239,29NJE@1,309TC@2,3F67W@33958,4IFD2@91061 NA|NA|NA GHBLAFEN_00419 1033837.WANG_0870 3.4e-130 471.1 Lactobacillaceae Bacteria 1U6GH@1239,29NJE@1,30ACF@2,3F7VG@33958,4IG8N@91061 NA|NA|NA K Helix-turn-helix XRE-family like proteins GHBLAFEN_00420 1033837.WANG_0869 0.0 1136.3 Lactobacillaceae Bacteria 1UI9D@1239,2EF0H@1,338TK@2,3F5C8@33958,4ISGU@91061 NA|NA|NA S SLAP domain GHBLAFEN_00421 405566.lhv_1940 5.9e-155 553.5 Lactobacillaceae glcU ko:K05340 ko00000,ko02000 2.A.7.5 Bacteria 1TQBN@1239,3F4K2@33958,4HAVH@91061,COG4975@1,COG4975@2 NA|NA|NA U sugar transport GHBLAFEN_00422 641146.HMPREF9020_01154 9.9e-233 812.4 Bifidobacteriales Bacteria 2GJK7@201174,4D1TR@85004,COG3464@1,COG3464@2 NA|NA|NA L Transposase GHBLAFEN_00423 326425.lhe_1055 3.4e-169 600.9 Lactobacillaceae Bacteria 1VI5W@1239,2E37J@1,32Y79@2,3F8SQ@33958,4HP73@91061 NA|NA|NA GHBLAFEN_00424 1033837.WANG_p1034 1.2e-32 145.2 Lactobacillaceae Bacteria 1TRSF@1239,3F3YG@33958,4HADR@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family GHBLAFEN_00425 1033837.WANG_p1034 2.2e-75 288.1 Lactobacillaceae Bacteria 1TRSF@1239,3F3YG@33958,4HADR@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family GHBLAFEN_00431 891391.LAC30SC_02360 2.7e-23 114.0 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3FCFA@33958,4HC8M@91061,COG2801@1,COG2801@2 NA|NA|NA L COG2963 Transposase and inactivated derivatives GHBLAFEN_00432 891391.LAC30SC_02360 3.6e-30 137.5 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3FCFA@33958,4HC8M@91061,COG2801@1,COG2801@2 NA|NA|NA L COG2963 Transposase and inactivated derivatives GHBLAFEN_00433 545697.HMPREF0216_00957 2e-23 115.9 Clostridiaceae Bacteria 1VWSC@1239,24W3Q@186801,2CEMS@1,342DU@2,36P07@31979 NA|NA|NA GHBLAFEN_00434 891391.LAC30SC_04140 8.1e-196 689.5 Lactobacillaceae Bacteria 1TRSF@1239,3FB5V@33958,4HAYI@91061,COG2826@1,COG2826@2 NA|NA|NA L COG2826 Transposase and inactivated derivatives, IS30 family GHBLAFEN_00435 405566.lhv_1082 3.6e-151 540.8 Lactobacillaceae xerD ko:K04763 ko00000,ko03036 Bacteria 1UFH8@1239,3F3KV@33958,4IES1@91061,COG4974@1,COG4974@2 NA|NA|NA L Phage integrase, N-terminal SAM-like domain GHBLAFEN_00436 326425.lhe_1037 2.7e-73 281.2 Lactobacillaceae Bacteria 1U66T@1239,2A0WQ@1,30P1T@2,3F77R@33958,4IFX9@91061 NA|NA|NA S Protein of unknown function (DUF3021) GHBLAFEN_00437 326425.lhe_1036 6.6e-75 286.6 Lactobacillaceae Bacteria 1VD10@1239,3F6QC@33958,4HMF3@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain GHBLAFEN_00438 1423748.BALB01000002_gene239 6.2e-196 689.9 Lactobacillaceae tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1TQDR@1239,3F4AX@33958,4HANB@91061,COG0533@1,COG0533@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction GHBLAFEN_00439 326425.lhe_1695 1.7e-102 378.6 Lactobacillaceae rimI 2.3.1.128 ko:K03789 ko00000,ko01000,ko03009 Bacteria 1V6KU@1239,3F522@33958,4HIKU@91061,COG0454@1,COG0456@2 NA|NA|NA K Ribosomal-protein-alanine acetyltransferase GHBLAFEN_00440 405566.lhv_0411 5e-131 473.8 Lactobacillaceae yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03016 Bacteria 1V4YX@1239,3F3WV@33958,4HHD7@91061,COG1214@1,COG1214@2 NA|NA|NA O Universal bacterial protein YeaZ GHBLAFEN_00441 1033837.WANG_0084 9.9e-86 322.8 Lactobacillaceae Bacteria 1VGAX@1239,2DNHW@1,32XKY@2,3FBRP@33958,4ISA7@91061 NA|NA|NA S ECF transporter, substrate-specific component GHBLAFEN_00442 1033837.WANG_0083 7.3e-143 513.1 Lactobacillaceae fat 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 Bacteria 1V3RB@1239,3F41B@33958,4HHJ4@91061,COG3884@1,COG3884@2 NA|NA|NA I Acyl-ACP thioesterase GHBLAFEN_00443 326425.lhe_1699 5.7e-155 553.5 Lactobacillaceae rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 1TP6U@1239,3F4AI@33958,4HAH8@91061,COG0313@1,COG0313@2 NA|NA|NA H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA GHBLAFEN_00444 1423748.BALB01000002_gene245 4.5e-58 230.3 Lactobacillaceae yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 Bacteria 1VA1F@1239,3F864@33958,4HKND@91061,COG4467@1,COG4467@2 NA|NA|NA L Involved in initiation control of chromosome replication GHBLAFEN_00445 326425.lhe_1701 5.7e-155 553.5 Lactobacillaceae holB 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TRVS@1239,3F50D@33958,4HA3T@91061,COG0470@1,COG0470@2 NA|NA|NA L DNA polymerase III GHBLAFEN_00446 405566.lhv_0405 1.9e-50 204.9 Lactobacillaceae yaaQ Bacteria 1V6NI@1239,3F6VW@33958,4HIHA@91061,COG3870@1,COG3870@2 NA|NA|NA S Cyclic-di-AMP receptor GHBLAFEN_00447 326425.lhe_1703 1.9e-115 421.8 Lactobacillaceae tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS02535 Bacteria 1V1HE@1239,3F4JR@33958,4HGWR@91061,COG0125@1,COG0125@2 NA|NA|NA F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis GHBLAFEN_00448 326425.lhe_1704 2.6e-33 147.5 Lactobacillaceae Bacteria 1U6E6@1239,29PC5@1,30AAD@2,3F7PR@33958,4IG5Y@91061 NA|NA|NA S Protein of unknown function (DUF2508) GHBLAFEN_00449 1423748.BALB01000002_gene251 1.6e-108 398.7 Lactobacillaceae recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1TR87@1239,3F4JQ@33958,4HAZR@91061,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO GHBLAFEN_00450 1423748.BALB01000002_gene252 5e-38 163.7 Lactobacillaceae yaaK ko:K09747 ko00000 Bacteria 1VA1S@1239,3F7F3@33958,4HKH3@91061,COG0718@1,COG0718@2 NA|NA|NA S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection GHBLAFEN_00451 405566.lhv_0400 0.0 1122.5 Lactobacillaceae dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02341,ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPS9@1239,3F3P2@33958,4HAUE@91061,COG2812@1,COG2812@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity GHBLAFEN_00452 326425.lhe_1708 6.9e-92 343.2 Lactobacillaceae tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 R10223 RC00477 ko00000,ko01000,ko03016 Bacteria 1V3HZ@1239,3F6IS@33958,4HH7S@91061,COG0590@1,COG0590@2 NA|NA|NA F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) GHBLAFEN_00453 326425.lhe_1709 7.7e-117 426.4 Lactobacillaceae rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1V1BG@1239,3F4NU@33958,4HHCA@91061,COG2813@1,COG2813@2 NA|NA|NA J Methyltransferase GHBLAFEN_00454 1423748.BALB01000002_gene255 1.4e-83 315.8 Lactobacillaceae rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172,2.1.1.80,3.1.1.61 ko:K00564,ko:K02026,ko:K10716,ko:K11070,ko:K13924,ko:K14393 ko02010,ko02020,ko02030,map02010,map02020,map02030 M00207,M00299,M00506 R07234 RC00003 ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035,ko03009 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6,2.A.21.7,3.A.1.1,3.A.1.11.1 Bacteria 1UI94@1239,3FBT5@33958,4HFS7@91061,COG1340@1,COG1340@2,COG2813@1,COG2813@2 NA|NA|NA J Ion channel GHBLAFEN_00455 1423748.BALB01000002_gene255 1.4e-35 155.2 Lactobacillaceae rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172,2.1.1.80,3.1.1.61 ko:K00564,ko:K02026,ko:K10716,ko:K11070,ko:K13924,ko:K14393 ko02010,ko02020,ko02030,map02010,map02020,map02030 M00207,M00299,M00506 R07234 RC00003 ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035,ko03009 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6,2.A.21.7,3.A.1.1,3.A.1.11.1 Bacteria 1UI94@1239,3FBT5@33958,4HFS7@91061,COG1340@1,COG1340@2,COG2813@1,COG2813@2 NA|NA|NA J Ion channel GHBLAFEN_00456 1423748.BALB01000002_gene256 1.6e-53 215.3 Lactobacillaceae rplL ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6EI@1239,3F6YA@33958,4HIGQ@91061,COG0222@1,COG0222@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation GHBLAFEN_00457 1423748.BALB01000002_gene257 3.5e-83 314.3 Lactobacillaceae rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3JJ@1239,3F4S4@33958,4HH0N@91061,COG0244@1,COG0244@2 NA|NA|NA J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors GHBLAFEN_00458 1423748.BALB01000002_gene258 1.4e-154 552.4 Lactobacillaceae yfdV GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07088 ko00000 iECW_1372.ECW_m2605,iWFL_1372.ECW_m2605 Bacteria 1VDS9@1239,3F5JF@33958,4HQT5@91061,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein GHBLAFEN_00459 272621.LBA0367 4.1e-10 69.3 Lactobacillaceae yfdV GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07088 ko00000 iECW_1372.ECW_m2605,iWFL_1372.ECW_m2605 Bacteria 1VDS9@1239,3F5JF@33958,4HQT5@91061,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein GHBLAFEN_00460 326425.lhe_1714 7.5e-118 429.9 Lactobacillaceae phoU ko:K02039 ko00000 Bacteria 1URN3@1239,3F46W@33958,4HEU9@91061,COG0704@1,COG0704@2 NA|NA|NA P Plays a role in the regulation of phosphate uptake GHBLAFEN_00461 326425.lhe_1715 7.8e-140 503.1 Lactobacillaceae pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 iLJ478.TM1261 Bacteria 1TP1M@1239,3F3SY@33958,4HAB1@91061,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system GHBLAFEN_00462 326425.lhe_1716 9.3e-144 516.2 Lactobacillaceae pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 iLJ478.TM1261 Bacteria 1TP1M@1239,3F3SY@33958,4HAB1@91061,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system GHBLAFEN_00463 326425.lhe_1717 7e-156 556.6 Lactobacillaceae pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TP74@1239,3F412@33958,4HAKF@91061,COG0581@1,COG0581@2 NA|NA|NA P Phosphate transport system permease protein PstA GHBLAFEN_00464 326425.lhe_1718 1.9e-173 615.1 Lactobacillaceae pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02037 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TSPP@1239,3F3NI@33958,4HC9H@91061,COG0573@1,COG0573@2 NA|NA|NA P probably responsible for the translocation of the substrate across the membrane GHBLAFEN_00465 405566.lhv_0387 1.4e-156 558.9 Lactobacillaceae pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TQ5X@1239,3F4ER@33958,4HBEB@91061,COG0226@1,COG0226@2 NA|NA|NA P Phosphate GHBLAFEN_00466 326425.lhe_1720 3.2e-124 451.1 Lactobacillaceae rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPTS@1239,3F3VQ@33958,4HAK4@91061,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release GHBLAFEN_00467 1423748.BALB01000002_gene267 6.9e-69 266.5 Lactobacillaceae rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1BS@1239,3F64I@33958,4HFQ0@91061,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors GHBLAFEN_00468 326425.lhe_1722 6.9e-101 373.2 Lactobacillaceae nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 1TR3P@1239,3F55W@33958,4HAJA@91061,COG0250@1,COG0250@2 NA|NA|NA K Participates in transcription elongation, termination and antitermination GHBLAFEN_00469 326425.lhe_1723 5.9e-24 115.9 Lactobacillaceae secE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VK48@1239,3F86Y@33958,4HR1W@91061,COG0690@1,COG0690@2 NA|NA|NA U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation GHBLAFEN_00470 1423748.BALB01000002_gene270 0.0 1118.6 Lactobacillaceae dxs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP37@1239,3F4RN@33958,4H9QW@91061,COG1154@1,COG1154@2 NA|NA|NA H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) GHBLAFEN_00471 405566.lhv_0375 1.3e-282 978.4 Lactobacillaceae gntK 2.7.1.12,2.7.1.17 ko:K00851,ko:K00854 ko00030,ko00040,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map01100,map01110,map01120,map01130,map01200 M00014 R01639,R01737 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ1I@1239,3F4R2@33958,4H9W6@91061,COG1070@1,COG1070@2 NA|NA|NA G Belongs to the FGGY kinase family GHBLAFEN_00472 272621.LBA0352 8.3e-34 149.1 Lactobacillaceae Bacteria 1U6KC@1239,29PH8@1,30AFD@2,3F83D@33958,4IGD6@91061 NA|NA|NA GHBLAFEN_00473 326425.lhe_1727 2.7e-94 351.3 Lactobacillaceae sigH ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Bacteria 1VG7U@1239,3F8D5@33958,4HNKD@91061,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family GHBLAFEN_00474 405566.lhv_0372 7.8e-140 503.1 Lactobacillaceae rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218,ko:K03437,ko:K12952 ko00000,ko01000,ko03009,ko03016 3.A.3.23 Bacteria 1TP9G@1239,3F3TD@33958,4HBBI@91061,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family GHBLAFEN_00475 326425.lhe_1729 7.9e-76 289.7 Lactobacillaceae mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 ko:K11145 ko00000,ko01000,ko03009 Bacteria 1VA5V@1239,3F6HS@33958,4HIM3@91061,COG1939@1,COG1939@2 NA|NA|NA J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) GHBLAFEN_00476 405566.lhv_0370 3.5e-274 950.3 Lactobacillaceae cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16,6.3.1.13 ko:K01883,ko:K15526 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECUMN_1333.ECUMN_0566,iJN746.PP_2905 Bacteria 1TP9D@1239,3F4K7@33958,4HA6D@91061,COG0215@1,COG0215@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family GHBLAFEN_00477 405566.lhv_0369 7.3e-291 1005.7 Lactobacillaceae gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009986,GO:0030246,GO:0030247,GO:0044424,GO:0044464,GO:2001065 6.1.1.17,6.1.1.24 ko:K01885,ko:K09698 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 iSB619.SA_RS02860 Bacteria 1TPJC@1239,3F3PR@33958,4HAKH@91061,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) GHBLAFEN_00478 1423748.BALB01000002_gene280 3e-254 884.0 Lactobacillaceae radA ko:K04485 ko00000,ko03400 Bacteria 1TQ7Y@1239,3F3W8@33958,4H9YC@91061,COG1066@1,COG1066@2 NA|NA|NA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function GHBLAFEN_00479 405566.lhv_0367 6.1e-102 376.7 Lactobacillaceae dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 ko:K01520,ko:K13038 ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100 M00053,M00120 R02100,R03269,R04231,R11896 RC00002,RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1V6HX@1239,3F65D@33958,4HIZ3@91061,COG0756@1,COG0756@2 NA|NA|NA F dUTP diphosphatase GHBLAFEN_00480 326425.lhe_1734 4.5e-54 216.9 Lactobacillaceae Bacteria 1U6EY@1239,2BRXH@1,32KXS@2,3F7RT@33958,4IG6S@91061 NA|NA|NA GHBLAFEN_00481 1074451.CRL705_1346 1e-14 84.7 Lactobacillaceae ko:K07483 ko00000 Bacteria 1VIEV@1239,3F6X7@33958,4HJSC@91061,COG2963@1,COG2963@2 NA|NA|NA L Transposase and inactivated derivatives GHBLAFEN_00482 525309.HMPREF0494_0079 7.9e-76 289.7 Lactobacillaceae birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 ko:K03524,ko:K04096 ko00780,ko01100,map00780,map01100 R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 Bacteria 1TQCU@1239,3F5HY@33958,4HB60@91061,COG0340@1,COG0340@2,COG1654@1,COG1654@2 NA|NA|NA H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor GHBLAFEN_00483 1321778.HMPREF1982_03103 8.5e-41 172.9 unclassified Clostridiales ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TP6H@1239,247JJ@186801,26A4W@186813,COG1136@1,COG1136@2 NA|NA|NA V ATPases associated with a variety of cellular activities GHBLAFEN_00484 891391.LAC30SC_01330 1.5e-63 248.8 Lactobacillaceae Bacteria 1UY99@1239,3F5UJ@33958,4IS32@91061,COG1403@1,COG1403@2,COG1479@1,COG1479@2 NA|NA|NA V Protein of unknown function DUF262 GHBLAFEN_00485 405566.lhv_1910 6.5e-13 79.0 Lactobacillaceae ko:K07785 ko02020,map02020 ko00000,ko00001,ko02000 2.A.1.31 Bacteria 1UI8U@1239,3FBSV@33958,4ISG9@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator Superfamily GHBLAFEN_00486 405566.lhv_1909 7.3e-113 413.3 Lactobacillaceae ropB Bacteria 1VD8E@1239,3F61C@33958,4HMD2@91061,COG1396@1,COG1396@2 NA|NA|NA K Transcriptional regulator GHBLAFEN_00487 1033837.WANG_p1133 5e-142 510.4 Lactobacillaceae Bacteria 1TP4A@1239,3F40X@33958,4HDAB@91061,COG3547@1,COG3547@2 NA|NA|NA L COG3547 Transposase and inactivated derivatives GHBLAFEN_00488 1423758.BN55_05380 1.6e-20 105.1 Lactobacillaceae Bacteria 1U869@1239,29QIX@1,30BIF@2,3FAKK@33958,4II3T@91061 NA|NA|NA GHBLAFEN_00499 405566.lhv_0235 2.1e-207 728.4 Lactobacillaceae glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042,ko:K11528 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP88@1239,3F4I3@33958,4H9V5@91061,COG1207@1,COG1207@2 NA|NA|NA M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain GHBLAFEN_00500 405566.lhv_0234 2.2e-148 531.6 Lactobacillaceae purR 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816,ko:K09685 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko03000,ko04147 Bacteria 1TPN9@1239,3F3NH@33958,4HB8I@91061,COG0503@1,COG0503@2 NA|NA|NA F pur operon repressor GHBLAFEN_00501 748671.LCRIS_00221 5e-38 163.3 Lactobacillaceae veg Bacteria 1VEQM@1239,3F7D3@33958,4HKF8@91061,COG4466@1,COG4466@2 NA|NA|NA S Biofilm formation stimulator VEG GHBLAFEN_00502 405566.lhv_0232 3.9e-159 567.4 Lactobacillaceae ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528,ko:K15256 R10716 RC00003,RC03257 ko00000,ko01000,ko03009,ko03016 Bacteria 1TP9W@1239,3F3VC@33958,4HA4R@91061,COG0030@1,COG0030@2 NA|NA|NA J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits GHBLAFEN_00503 326425.lhe_1856 7.2e-98 363.2 Lactobacillaceae rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985,ko:K07476 ko00000,ko01000 Bacteria 1V3K3@1239,3F64F@33958,4HH5Y@91061,COG1658@1,COG1658@2 NA|NA|NA J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step GHBLAFEN_00504 405566.lhv_0230 4.6e-148 530.4 Lactobacillaceae tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 ko:K03424 ko00000,ko01000 Bacteria 1TNY1@1239,3F3N2@33958,4HA74@91061,COG0084@1,COG0084@2 NA|NA|NA L hydrolase, TatD family GHBLAFEN_00505 405566.lhv_0229 0.0 1328.2 Lactobacillaceae metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPA1@1239,3F3XR@33958,4H9VC@91061,COG0143@1,COG0143@2 NA|NA|NA J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation GHBLAFEN_00506 326425.lhe_1859 0.0 1676.0 Lactobacillaceae mgtA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132 3.6.3.2 ko:K01531 ko00000,ko01000 3.A.3.4 iSF_1195.SF4248 Bacteria 1TPF5@1239,3F4E0@33958,4HBQJ@91061,COG0474@1,COG0474@2 NA|NA|NA P COG0474 Cation transport ATPase GHBLAFEN_00507 405566.lhv_0227 1.3e-108 399.1 Lactobacillaceae ko:K06872,ko:K07507 ko00000,ko02000 9.B.20 Bacteria 1V5YF@1239,3F5HD@33958,4HJVB@91061,COG1512@1,COG1512@2 NA|NA|NA S TPM domain GHBLAFEN_00508 326425.lhe_1861 5.5e-91 340.1 Lactobacillaceae comEB 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 Bacteria 1V3PU@1239,3FC8D@33958,4HEJU@91061,COG2131@1,COG2131@2 NA|NA|NA F MafB19-like deaminase GHBLAFEN_00509 1423748.BALB01000008_gene948 1.1e-192 679.1 Lactobacillaceae trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPY7@1239,3F3V6@33958,4HA1K@91061,COG0180@1,COG0180@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family GHBLAFEN_00510 326425.lhe_1863 4.5e-114 417.2 Lactobacillaceae Bacteria 1TRRV@1239,3F5AJ@33958,4HHE2@91061,COG2135@1,COG2135@2 NA|NA|NA E Belongs to the SOS response-associated peptidase family GHBLAFEN_00512 405566.lhv_0224 4.9e-114 417.2 Lactobacillaceae Bacteria 1UG72@1239,2BFBV@1,3294Z@2,3F5KI@33958,4IF41@91061 NA|NA|NA GHBLAFEN_00513 405566.lhv_0223 1.8e-75 288.5 Lactobacillaceae greA ko:K03624,ko:K04760 ko00000,ko03021 Bacteria 1V1G3@1239,3F6ZK@33958,4HW8H@91061,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides GHBLAFEN_00514 1423748.BALB01000008_gene944 2.6e-68 264.6 Lactobacillaceae hsp ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 1VG0E@1239,3FB63@33958,4HIUZ@91061,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family GHBLAFEN_00515 326425.lhe_1868 8.8e-256 889.0 Lactobacillaceae pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 1TRJN@1239,3F3QA@33958,4HBZ9@91061,COG3579@1,COG3579@2 NA|NA|NA E aminopeptidase GHBLAFEN_00516 326425.lhe_1873 6.3e-210 736.5 Lactobacillaceae guaB GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027 Bacteria 1TNZ1@1239,3F3XN@33958,4H9V3@91061,COG0516@1,COG0516@2 NA|NA|NA F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides GHBLAFEN_00517 326425.lhe_1876 2.1e-117 428.3 Lactobacillaceae ypgQ ko:K06950 ko00000 Bacteria 1V7IZ@1239,3F3PN@33958,4HIVB@91061,COG1418@1,COG1418@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. GHBLAFEN_00518 405566.lhv_0212 7.9e-257 892.5 Lactobacillaceae pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 1TRJN@1239,3F3QA@33958,4HBZ9@91061,COG3579@1,COG3579@2 NA|NA|NA E aminopeptidase GHBLAFEN_00520 405566.lhv_0209 5.4e-21 106.3 Lactobacillaceae Bacteria 1U655@1239,2BZTJ@1,30A3I@2,3F72R@33958,4IFUX@91061 NA|NA|NA GHBLAFEN_00521 1423748.BALB01000008_gene938 9.7e-244 849.0 Lactobacillaceae tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iAF1260.b1637,iBWG_1329.BWG_1452,iECDH10B_1368.ECDH10B_1771,iECDH1ME8569_1439.ECDH1ME8569_1581,iECH74115_1262.ECH74115_2349,iECIAI39_1322.ECIAI39_1418,iECNA114_1301.ECNA114_1685,iECO103_1326.ECO103_1778,iECO111_1330.ECO111_2107,iECO26_1355.ECO26_2366,iECSE_1348.ECSE_1760,iECSF_1327.ECSF_1500,iECSP_1301.ECSP_2202,iECUMN_1333.ECUMN_1928,iECW_1372.ECW_m1805,iECs_1301.ECs2346,iEKO11_1354.EKO11_2137,iETEC_1333.ETEC_1672,iEcDH1_1363.EcDH1_2003,iEcE24377_1341.EcE24377A_1847,iEcHS_1320.EcHS_A1713,iEcSMS35_1347.EcSMS35_1562,iEcolC_1368.EcolC_1992,iJO1366.b1637,iSFV_1184.SFV_1654,iSF_1195.SF1662,iSSON_1240.SSON_1519,iSbBS512_1146.SbBS512_E1829,iUMNK88_1353.UMNK88_2097,iWFL_1372.ECW_m1805,iY75_1357.Y75_RS08585 Bacteria 1TPGN@1239,3F48J@33958,4H9YV@91061,COG0162@1,COG0162@2 NA|NA|NA J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) GHBLAFEN_00522 326425.lhe_1881 9e-267 925.6 Lactobacillaceae Bacteria 1UGQV@1239,2A3XC@1,30SFQ@2,3F5YM@33958,4IF8A@91061 NA|NA|NA S Fibronectin type III domain GHBLAFEN_00523 326425.lhe_1882 0.0 1890.2 Lactobacillaceae XK27_08315 Bacteria 1TQYQ@1239,3F3NY@33958,4HBY6@91061,COG1368@1,COG1368@2 NA|NA|NA M Sulfatase GHBLAFEN_00524 405566.lhv_0205 1.4e-110 405.6 Lactobacillaceae plsY 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1VAFC@1239,3F5HQ@33958,4HMJZ@91061,COG0344@1,COG0344@2 NA|NA|NA I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP GHBLAFEN_00525 405566.lhv_0204 3.6e-202 710.7 Lactobacillaceae brpA Bacteria 1TR1B@1239,3F3MQ@33958,4HA09@91061,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-like function transcriptional attenuator common domain protein GHBLAFEN_00526 405566.lhv_0203 5.3e-101 373.6 Lactobacillaceae Bacteria 1U5EB@1239,3F5Q4@33958,4IF5R@91061,COG2017@1,COG2017@2 NA|NA|NA G Aldose 1-epimerase GHBLAFEN_00527 405566.lhv_0202 8.2e-108 396.4 Lactobacillaceae pcp GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.19.3 ko:K01304 ko00000,ko01000,ko01002 Bacteria 1TRRX@1239,3F46I@33958,4HCIJ@91061,COG2039@1,COG2039@2 NA|NA|NA O Removes 5-oxoproline from various penultimate amino acid residues except L-proline GHBLAFEN_00528 326425.lhe_1887 1.9e-132 478.4 Lactobacillaceae gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1TQFP@1239,3F3SK@33958,4HAW7@91061,COG0588@1,COG0588@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate GHBLAFEN_00529 326425.lhe_1888 1.1e-133 482.6 Lactobacillaceae Bacteria 1U59S@1239,2E0R1@1,32W9E@2,3F5B0@33958,4IF1B@91061 NA|NA|NA GHBLAFEN_00530 272621.LBA0183 4.7e-66 257.3 Lactobacillaceae Bacteria 1U5C8@1239,29NPN@1,309MJ@2,3F5HZ@33958,4IF3G@91061 NA|NA|NA GHBLAFEN_00531 1121115.AXVN01000011_gene3458 3e-16 92.4 Blautia cps Bacteria 1VVRP@1239,24GDS@186801,3Y0FR@572511,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 GHBLAFEN_00532 1423748.BALB01000001_gene167 2.3e-99 368.2 Lactobacillaceae clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 1TQ91@1239,3F3M0@33958,4HA8J@91061,COG0740@1,COG0740@2 NA|NA|NA O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins GHBLAFEN_00533 326425.lhe_0278 9.9e-86 322.8 Lactobacillaceae GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 ko:K14060 ko00000 Bacteria 1V51N@1239,3F51V@33958,4HDX2@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain GHBLAFEN_00534 326425.lhe_0260 1.2e-22 111.7 Lactobacillaceae Bacteria 1U4M0@1239,3F8FR@33958,4IECV@91061,COG5547@1,COG5547@2 NA|NA|NA S Small integral membrane protein (DUF2273) GHBLAFEN_00535 585524.HMPREF0493_1684 2.4e-127 461.5 Lactobacillaceae Bacteria 1UZVA@1239,3F4KP@33958,4HH09@91061,COG3039@1,COG3039@2 NA|NA|NA L An automated process has identified a potential problem with this gene model GHBLAFEN_00538 585524.HMPREF0493_0599 9.5e-25 118.6 Firmicutes cspC ko:K03704 ko00000,ko03000 Bacteria 1VBBH@1239,COG1278@1,COG1278@2 NA|NA|NA K Probable zinc-ribbon domain GHBLAFEN_00539 326425.lhe_1352 6.5e-178 629.8 Lactobacillaceae Bacteria 1V2AW@1239,3F3N7@33958,4HU2V@91061,COG0657@1,COG0657@2 NA|NA|NA I Carboxylesterase family GHBLAFEN_00540 405566.lhv_1435 1.1e-64 252.3 Lactobacillaceae arsC 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1VA5Q@1239,3F72U@33958,4HKQQ@91061,COG1393@1,COG1393@2 NA|NA|NA P Belongs to the ArsC family GHBLAFEN_00541 748671.LCRIS_01361 4e-27 127.1 Lactobacillaceae Bacteria 1U6JT@1239,2DKR3@1,30AEW@2,3F81U@33958,4IGCA@91061 NA|NA|NA GHBLAFEN_00542 525365.HMPREF0548_0800 6.9e-62 243.8 Lactobacillaceae Bacteria 1VMSZ@1239,2DF54@1,32U4N@2,3F6U1@33958,4HSRG@91061 NA|NA|NA S Bacterial PH domain GHBLAFEN_00543 405566.lhv_1436 0.0 1586.2 Lactobacillaceae pepX 3.4.14.11 ko:K01281 ko00000,ko01000,ko01002 Bacteria 1TT78@1239,3FCF2@33958,4IRQ0@91061,COG2936@1,COG2936@2 NA|NA|NA E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline GHBLAFEN_00544 891391.LAC30SC_00110 2.5e-120 438.3 Lactobacillaceae aacC 2.3.1.81 ko:K00662 ko00000,ko01000,ko01504 Bacteria 1V2QD@1239,3F635@33958,4HC3S@91061,COG2746@1,COG2746@2 NA|NA|NA V Aminoglycoside 3-N-acetyltransferase GHBLAFEN_00545 1033837.WANG_0359 2.2e-142 511.5 Lactobacillaceae 2.4.2.3 ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01876,R02484,R08229 RC00063 ko00000,ko00001,ko01000 Bacteria 1TQ71@1239,3F3UX@33958,4IRA8@91061,COG2820@1,COG2820@2 NA|NA|NA F Phosphorylase superfamily GHBLAFEN_00546 1033837.WANG_0358 1.8e-144 518.5 Lactobacillaceae 2.4.2.3 ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01876,R02484,R08229 RC00063 ko00000,ko00001,ko01000 Bacteria 1TQ71@1239,3F3UX@33958,4IRA8@91061,COG2820@1,COG2820@2 NA|NA|NA F Phosphorylase superfamily GHBLAFEN_00547 1033837.WANG_0357 2e-149 535.0 Lactobacillaceae 2.7.1.89 ko:K07251 ko00730,ko01100,map00730,map01100 R02134 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1VGF6@1239,3F5XT@33958,4HPU6@91061,COG0510@1,COG0510@2 NA|NA|NA M Phosphotransferase enzyme family GHBLAFEN_00548 1033837.WANG_0356 5.9e-91 340.1 Lactobacillaceae Bacteria 1UIME@1239,3F6E7@33958,4ISNB@91061,COG0645@1,COG0645@2 NA|NA|NA S AAA domain GHBLAFEN_00549 1033837.WANG_0355 5.2e-22 109.4 Bacteria cdd GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009972,GO:0009987,GO:0016020,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019856,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042455,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046108,GO:0046109,GO:0046112,GO:0046131,GO:0046132,GO:0046133,GO:0046134,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0072529,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 2.4.2.4,3.5.4.5 ko:K00758,ko:K01489 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 R01570,R01878,R02484,R02485,R08221,R08222,R08230 RC00063,RC00074,RC00514 ko00000,ko00001,ko01000 Bacteria COG0295@1,COG0295@2 NA|NA|NA F cytidine deaminase activity GHBLAFEN_00550 1423758.BN55_08820 4.3e-21 106.7 Lactobacillaceae cdd GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009972,GO:0009987,GO:0016020,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019856,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042455,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046108,GO:0046109,GO:0046112,GO:0046131,GO:0046132,GO:0046133,GO:0046134,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0072529,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 2.4.2.4,3.5.4.5 ko:K00758,ko:K01489 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 R01570,R01878,R02484,R02485,R08221,R08222,R08230 RC00063,RC00074,RC00514 ko00000,ko00001,ko01000 Bacteria 1V7IK@1239,3FC88@33958,4HMND@91061,COG0295@1,COG0295@2 NA|NA|NA F Cytidine and deoxycytidylate deaminase zinc-binding region GHBLAFEN_00551 1423758.BN55_08815 5.4e-136 490.7 Bacteria yxaM Bacteria COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GHBLAFEN_00552 1033837.WANG_0352 8e-51 206.1 Lactobacillaceae 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1U7WX@1239,3F4BS@33958,4HHQT@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain GHBLAFEN_00553 1033837.WANG_0351 2.9e-31 140.6 Lactobacillaceae Bacteria 1U6JV@1239,2DKR4@1,30AEY@2,3F820@33958,4IGCE@91061 NA|NA|NA S Protein of unknown function (DUF3923) GHBLAFEN_00554 1033837.WANG_0350 3.3e-43 180.6 Lactobacillaceae ko:K07473 ko00000,ko02048 Bacteria 1U67K@1239,29P71@1,30A54@2,3F79C@33958,4IFY5@91061 NA|NA|NA GHBLAFEN_00555 748671.LCRIS_01029 4.4e-56 223.8 Lactobacillaceae Bacteria 1UPY9@1239,2DMQA@1,32SZE@2,3F6TX@33958,4IVD8@91061 NA|NA|NA GHBLAFEN_00556 748671.LCRIS_01028 4.7e-26 123.2 Lactobacillaceae Bacteria 1VJNA@1239,3F7BG@33958,4I1AJ@91061,COG1694@1,COG1694@2 NA|NA|NA S MazG-like family GHBLAFEN_00557 1033837.WANG_0348 4.9e-148 530.4 Lactobacillaceae Bacteria 1VCVA@1239,2E1K9@1,32WXS@2,3FBP4@33958,4HN4A@91061 NA|NA|NA S Protein of unknown function (DUF2785) GHBLAFEN_00558 1033837.WANG_0347 9.3e-80 302.8 Lactobacillaceae Bacteria 1V125@1239,3F5TK@33958,4HFVJ@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain GHBLAFEN_00559 1033837.WANG_0346 1.5e-16 91.3 Lactobacillaceae Bacteria 1U8GF@1239,2BU1J@1,32PA8@2,3FAYE@33958,4IIE8@91061 NA|NA|NA GHBLAFEN_00560 1033837.WANG_0346 8.5e-18 95.5 Lactobacillaceae Bacteria 1U8GF@1239,2BU1J@1,32PA8@2,3FAYE@33958,4IIE8@91061 NA|NA|NA GHBLAFEN_00561 1033837.WANG_0345 2.3e-80 304.7 Lactobacillaceae msrB 1.8.4.11,1.8.4.12 ko:K07305,ko:K12267 ko00000,ko01000 Bacteria 1UPN0@1239,3F6H4@33958,4HGWN@91061,COG0229@1,COG0229@2 NA|NA|NA O peptide methionine sulfoxide reductase GHBLAFEN_00562 1033837.WANG_0344 2.9e-47 194.1 Lactobacillaceae Bacteria 1U63R@1239,2DKNK@1,30A2I@2,3F6YT@33958,4IFT6@91061 NA|NA|NA GHBLAFEN_00563 748671.LCRIS_01367 2.3e-43 181.4 Lactobacillaceae glcU ko:K05340 ko00000,ko02000 2.A.7.5 Bacteria 1TQBN@1239,3F4K2@33958,4HAVH@91061,COG4975@1,COG4975@2 NA|NA|NA U sugar transport GHBLAFEN_00564 1423748.BALB01000027_gene1830 1.9e-84 318.5 Lactobacillaceae glcU ko:K05340 ko00000,ko02000 2.A.7.5 Bacteria 1TQBN@1239,3F4K2@33958,4HAVH@91061,COG4975@1,COG4975@2 NA|NA|NA U sugar transport GHBLAFEN_00565 1033837.WANG_0343 1.5e-108 398.7 Lactobacillaceae Bacteria 1U50X@1239,29NII@1,309GE@2,3F8K2@33958,4IGPK@91061 NA|NA|NA S Domain of unknown function (DUF4411) GHBLAFEN_00566 1033837.WANG_0342 1.2e-219 768.8 Lactobacillaceae Bacteria 1TQAC@1239,3F5G6@33958,4HJ3C@91061,COG2856@1,COG2856@2 NA|NA|NA E IrrE N-terminal-like domain GHBLAFEN_00567 163908.KB235895_gene5065 5.6e-08 66.2 Nostocales yfdK Bacteria 1GBDN@1117,1HQE7@1161,COG2110@1,COG2110@2 NA|NA|NA S phosphatase homologous to the C-terminal domain of histone macroH2A1 GHBLAFEN_00568 1033837.WANG_0339 0.0 2097.8 Lactobacillaceae carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPID@1239,3F3MD@33958,4HAEY@91061,COG0458@1,COG0458@2 NA|NA|NA F Carbamoyl-phosphate synthase GHBLAFEN_00569 405566.lhv_1444 4.2e-211 740.3 Lactobacillaceae carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383,iYO844.BSU15510 Bacteria 1TQ8N@1239,3F43R@33958,4H9Z0@91061,COG0505@1,COG0505@2 NA|NA|NA F Carbamoyl-phosphate synthetase glutamine chain GHBLAFEN_00570 405566.lhv_1445 1.4e-242 845.1 Lactobacillaceae pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPQM@1239,3F3S3@33958,4HA90@91061,COG0044@1,COG0044@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily GHBLAFEN_00571 390333.Ldb2112 2.6e-180 637.9 Lactobacillaceae pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00608,ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15490 Bacteria 1TQ96@1239,3F4BQ@33958,4H9M6@91061,COG0540@1,COG0540@2 NA|NA|NA F Belongs to the ATCase OTCase family GHBLAFEN_00572 1033837.WANG_0335 1.1e-92 345.9 Lactobacillaceae pyrR GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000,ko03000 iHN637.CLJU_RS05275 Bacteria 1V3GV@1239,3F4SR@33958,4HGYE@91061,COG2065@1,COG2065@2 NA|NA|NA F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant GHBLAFEN_00573 1033837.WANG_0334 1.3e-165 589.0 Lactobacillaceae pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15540 Bacteria 1TPFV@1239,3F4PJ@33958,4HA5H@91061,COG0167@1,COG0167@2 NA|NA|NA F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily GHBLAFEN_00574 1033837.WANG_0333 2.9e-120 438.0 Lactobacillaceae pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750 Bacteria 1TPPH@1239,3F47Y@33958,4HAJ2@91061,COG0284@1,COG0284@2 NA|NA|NA F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) GHBLAFEN_00575 326425.lhe_1368 8.7e-113 412.9 Lactobacillaceae pyrE 2.4.2.10,4.1.1.23 ko:K00762,ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15560 Bacteria 1V1BZ@1239,3F487@33958,4HFV7@91061,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) GHBLAFEN_00576 326425.lhe_0819 2.2e-54 218.0 Lactobacillaceae Bacteria 1U6DY@1239,2A5PG@1,30UEB@2,3F7PE@33958,4IG5S@91061 NA|NA|NA S Protein of unknown function (DUF3397) GHBLAFEN_00577 326425.lhe_0818 6.5e-13 79.0 Lactobacillaceae Bacteria 1TV7P@1239,29GVY@1,303TQ@2,3F8AT@33958,4I8MD@91061 NA|NA|NA S Protein of unknown function (DUF4044) GHBLAFEN_00578 1033837.WANG_1685 2e-85 321.6 Lactobacillaceae tlpA2 ko:K07491 ko00000 Bacteria 1VAIQ@1239,3F68H@33958,4HI29@91061,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like GHBLAFEN_00579 326425.lhe_1849 5.4e-59 233.4 Lactobacillaceae Bacteria 1U593@1239,2DKIG@1,309K1@2,3F586@33958,4IF0E@91061 NA|NA|NA GHBLAFEN_00580 326425.lhe_0219 3.3e-87 327.8 Lactobacillaceae Bacteria 1UGDF@1239,29V9A@1,30GPA@2,3F5SI@33958,4IF6B@91061 NA|NA|NA GHBLAFEN_00581 1423743.JCM14108_3234 2e-13 80.5 Lactobacillaceae Bacteria 1TQAX@1239,3F429@33958,4HCFF@91061,COG1961@1,COG1961@2 NA|NA|NA L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed GHBLAFEN_00582 1423816.BACQ01000072_gene2582 8.9e-75 286.2 Lactobacillaceae tnpR Bacteria 1UZM8@1239,3FBG8@33958,4IQ67@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain GHBLAFEN_00583 748671.LCRIS_00540 1.8e-130 471.9 Lactobacillaceae Bacteria 1VRTR@1239,2C8DD@1,33PMV@2,3F5Z5@33958,4HTAR@91061 NA|NA|NA S Phage Mu protein F like protein GHBLAFEN_00584 278197.PEPE_0507 1.2e-12 79.0 Lactobacillaceae ytgB Bacteria 1VENK@1239,3F7EK@33958,4HNKV@91061,COG2261@1,COG2261@2 NA|NA|NA S Transglycosylase associated protein GHBLAFEN_00585 334390.LAF_0706 1.2e-123 449.1 Lactobacillaceae tnp ko:K07498 ko00000 Bacteria 1TTKR@1239,3F4NE@33958,4HCB4@91061,COG3316@1,COG3316@2 NA|NA|NA L DDE domain GHBLAFEN_00586 1423743.JCM14108_3234 3.4e-56 224.2 Lactobacillaceae Bacteria 1TQAX@1239,3F429@33958,4HCFF@91061,COG1961@1,COG1961@2 NA|NA|NA L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed GHBLAFEN_00587 1423748.BALB01000005_gene728 4.9e-90 337.0 Lactobacillaceae Bacteria 1UTR4@1239,3F4XR@33958,4HG6W@91061,COG3385@1,COG3385@2 NA|NA|NA L Transposase DDE domain GHBLAFEN_00590 326425.lhe_0465 7.6e-157 559.7 Lactobacillaceae Bacteria 1V192@1239,3F52D@33958,4IQTP@91061,COG0846@1,COG0846@2 NA|NA|NA K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form GHBLAFEN_00591 405566.lhv_1753 1.1e-159 569.3 Lactobacillaceae dnaQ 2.7.7.7 ko:K02342,ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TRS5@1239,3F546@33958,4HFJA@91061,COG2176@1,COG2176@2 NA|NA|NA L EXOIII GHBLAFEN_00592 326425.lhe_0467 8.5e-159 566.2 Lactobacillaceae endA ko:K15051 ko00000 Bacteria 1V4X2@1239,3F3Y8@33958,4HIF5@91061,COG2169@1,COG2169@2 NA|NA|NA F DNA RNA non-specific endonuclease GHBLAFEN_00593 405566.lhv_1751 5e-281 973.0 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase GHBLAFEN_00594 405566.lhv_1750 3.9e-201 707.2 Lactobacillaceae malK ko:K10112,ko:K17240 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00599,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.38 iLJ478.TM0421 Bacteria 1TP2M@1239,3FC3J@33958,4HBKK@91061,COG3842@1,COG3842@2 NA|NA|NA P ATPases associated with a variety of cellular activities GHBLAFEN_00595 405566.lhv_1749 2.1e-157 561.6 Lactobacillaceae gtsB ko:K02025,ko:K15771 ko02010,map02010 M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2 Bacteria 1TREE@1239,3F464@33958,4HCD0@91061,COG1175@1,COG1175@2 NA|NA|NA P ABC-type sugar transport systems, permease components GHBLAFEN_00596 326425.lhe_0471 4.7e-146 523.9 Lactobacillaceae gtsC ko:K02026 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 1TRCP@1239,3FC8G@33958,4HBK1@91061,COG0395@1,COG0395@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component GHBLAFEN_00597 405566.lhv_1747 3.5e-257 893.6 Lactobacillaceae YSH1 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1UDEF@1239,3F4WJ@33958,4HIN2@91061,COG0595@1,COG0595@2 NA|NA|NA S Zn-dependent metallo-hydrolase RNA specificity domain GHBLAFEN_00598 405566.lhv_1745 1.8e-240 838.2 Lactobacillaceae ko:K02027,ko:K05813 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 Bacteria 1TS64@1239,3F4P5@33958,4HEKH@91061,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein GHBLAFEN_00599 405566.lhv_1744 5.3e-159 567.0 Lactobacillaceae corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1TPSV@1239,3FCA3@33958,4HAPC@91061,COG0598@1,COG0598@2 NA|NA|NA P CorA-like Mg2+ transporter protein GHBLAFEN_00600 326425.lhe_0475 1e-157 562.8 Lactobacillaceae 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1U564@1239,3F4WE@33958,4IEXG@91061,COG2367@1,COG2367@2 NA|NA|NA V Beta-lactamase enzyme family GHBLAFEN_00601 405566.lhv_1742 3.3e-98 364.4 Lactobacillaceae yobS GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 Bacteria 1V1DM@1239,3F5CS@33958,4HG0Y@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family GHBLAFEN_00602 326425.lhe_0477 0.0 1214.5 Lactobacillaceae ydgH GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006790,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0030312,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046505,GO:0046506,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901576 ko:K06994,ko:K07003 ko00000 Bacteria 1TQ7C@1239,3FCCY@33958,4HBM6@91061,COG1511@1,COG1511@2,COG2409@1,COG2409@2 NA|NA|NA S MMPL family GHBLAFEN_00603 405566.lhv_1740 3.7e-148 531.2 Lactobacillaceae Bacteria 1U58Z@1239,29NMZ@1,309JX@2,3F573@33958,4IF0A@91061 NA|NA|NA GHBLAFEN_00604 326425.lhe_0479 2.5e-261 907.5 Lactobacillaceae gabD 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4S@1239,3F47F@33958,4H9MF@91061,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family GHBLAFEN_00605 326425.lhe_0480 5.9e-126 456.8 Lactobacillaceae hipB GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K15773 ko00000,ko02048,ko03000 Bacteria 1VBK2@1239,3FBE7@33958,4HCZ9@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix GHBLAFEN_00606 405566.lhv_1737 1.3e-153 548.9 Lactobacillaceae Bacteria 1VEC5@1239,3F50A@33958,4HKY6@91061,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold GHBLAFEN_00607 1423748.BALB01000026_gene1814 2.8e-108 397.9 Lactobacillaceae yjbF Bacteria 1V7NH@1239,3F3SV@33958,4HIU5@91061,COG0398@1,COG0398@2 NA|NA|NA S SNARE associated Golgi protein GHBLAFEN_00608 405566.lhv_1735 2.3e-96 358.2 Lactobacillaceae Bacteria 1V49W@1239,3F5A6@33958,4HHAP@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain GHBLAFEN_00609 405566.lhv_1734 3.4e-252 877.1 Lactobacillaceae serS GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF987.Gmet_3528,iSDY_1059.SDY_2368 Bacteria 1TP4W@1239,3F3M6@33958,4H9Y4@91061,COG0172@1,COG0172@2 NA|NA|NA J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) GHBLAFEN_00610 1033837.WANG_p1195 2.4e-37 161.4 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TRNY@1239,3F55P@33958,4HBKP@91061,COG0675@1,COG0675@2 NA|NA|NA L transposase, IS605 OrfB family GHBLAFEN_00611 1423748.BALB01000020_gene1637 1.3e-44 185.3 Lactobacillaceae Bacteria 1U71I@1239,2BVUC@1,30AS9@2,3F8UZ@33958,4IGW0@91061 NA|NA|NA GHBLAFEN_00612 326425.lhe_0589 1.2e-166 592.4 Lactobacillaceae galU 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ24@1239,3F45A@33958,4HATY@91061,COG1210@1,COG1210@2 NA|NA|NA M UTP-glucose-1-phosphate uridylyltransferase GHBLAFEN_00613 326425.lhe_0588 8.3e-152 543.1 Lactobacillaceae yihY ko:K07058 ko00000 Bacteria 1U7HM@1239,3F4TC@33958,4H9MJ@91061,COG1295@1,COG1295@2 NA|NA|NA S Belongs to the UPF0761 family GHBLAFEN_00614 326425.lhe_0587 1.9e-163 581.6 Lactobacillaceae map GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 1TQC1@1239,3F3MK@33958,4H9S9@91061,COG0024@1,COG0024@2 NA|NA|NA E Methionine Aminopeptidase GHBLAFEN_00615 326425.lhe_0586 1.6e-79 302.0 Lactobacillaceae fld ko:K03839 ko00000 Bacteria 1V7AG@1239,3F6HY@33958,4HMJF@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin GHBLAFEN_00616 405566.lhv_0653 1.8e-87 328.6 Lactobacillaceae gtcA GO:0000166,GO:0003674,GO:0003824,GO:0003870,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009987,GO:0016020,GO:0016410,GO:0016491,GO:0016620,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0016903,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 Bacteria 1VESW@1239,3F4GH@33958,4HNK7@91061,COG2246@1,COG2246@2 NA|NA|NA S Teichoic acid glycosylation protein GHBLAFEN_00617 405566.lhv_0652 1.7e-215 755.0 Lactobacillaceae mnaA 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1TQZT@1239,3F3KQ@33958,4HBI3@91061,COG0381@1,COG0381@2 NA|NA|NA G Belongs to the UDP-N-acetylglucosamine 2-epimerase family GHBLAFEN_00618 1423748.BALB01000004_gene587 2.7e-25 120.6 Lactobacillaceae Bacteria 1U6PN@1239,29PJM@1,30AHS@2,3F89D@33958,4IGGM@91061 NA|NA|NA GHBLAFEN_00620 326425.lhe_0581 1.5e-242 845.1 Lactobacillaceae celB GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264,GO:1902815 ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 iECABU_c1320.ECABU_c19930 Bacteria 1TP8D@1239,3F4VG@33958,4H9W2@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane GHBLAFEN_00621 405566.lhv_0650 1.1e-207 729.2 Lactobacillaceae yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TQ9R@1239,3F4K8@33958,4HANR@91061,COG0513@1,COG0513@2 NA|NA|NA L DEAD DEAH box helicase GHBLAFEN_00622 405566.lhv_0649 7.5e-129 466.5 Lactobacillaceae ko:K07273 ko00000 Bacteria 1V484@1239,3F4K0@33958,4HQWA@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 GHBLAFEN_00623 326425.lhe_0578 1.3e-227 795.4 Lactobacillaceae potE ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ48@1239,3F3YJ@33958,4HBGT@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid GHBLAFEN_00624 326425.lhe_0577 4.9e-102 377.1 Lactobacillaceae hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 Bacteria 1V1C9@1239,3F56C@33958,4HFZ2@91061,COG0634@1,COG0634@2 NA|NA|NA F Belongs to the purine pyrimidine phosphoribosyltransferase family GHBLAFEN_00625 405566.lhv_0645 1.1e-237 828.9 Lactobacillaceae yhdP ko:K03699,ko:K06189 ko00000,ko02000,ko02042 9.A.40.1.2 Bacteria 1TPN0@1239,3F3TX@33958,4H9SB@91061,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain GHBLAFEN_00626 1423748.BALB01000004_gene580 1.5e-30 138.3 Lactobacillaceae Bacteria 1V6AG@1239,3F6YM@33958,4HN5N@91061,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase GHBLAFEN_00627 1423748.BALB01000004_gene580 1.5e-14 84.3 Lactobacillaceae Bacteria 1V6AG@1239,3F6YM@33958,4HN5N@91061,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase GHBLAFEN_00628 405566.lhv_2311 1.6e-39 168.3 Lactobacillaceae Bacteria 1U6H9@1239,29PEW@1,30AD2@2,3F7X8@33958,4IG9K@91061 NA|NA|NA GHBLAFEN_00629 405566.lhv_0640 4.2e-86 323.9 Lactobacillaceae pts23A ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1 Bacteria 1VAEB@1239,3FC0X@33958,4HIPR@91061,COG2190@1,COG2190@2 NA|NA|NA G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 GHBLAFEN_00630 1423748.BALB01000004_gene578 1.9e-73 282.0 Lactobacillaceae Bacteria 1U5P7@1239,2CJCY@1,309TS@2,3F69B@33958,4IFDR@91061 NA|NA|NA GHBLAFEN_00631 1423748.BALB01000004_gene577 1.8e-136 491.9 Lactobacillaceae glvR ko:K03481 ko00000,ko03000 Bacteria 1V2J8@1239,3FBJH@33958,4IQVX@91061,COG1737@1,COG1737@2 NA|NA|NA K Helix-turn-helix domain, rpiR family GHBLAFEN_00632 1423748.BALB01000004_gene576 0.0 1190.6 Lactobacillaceae glvC 2.7.1.199,2.7.1.208 ko:K02749,ko:K02750,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 M00266,M00268 R02738,R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.10,4.A.1.1.16,4.A.1.1.3,4.A.1.1.4,4.A.1.1.8 Bacteria 1TPJ8@1239,3F44V@33958,4HA8X@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2 NA|NA|NA G phosphotransferase system, EIIB GHBLAFEN_00633 1423748.BALB01000004_gene575 2.2e-86 325.1 Lactobacillaceae Bacteria 1TR16@1239,3F55S@33958,4HCZ6@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase GHBLAFEN_00634 272621.LBA0602 3.3e-11 74.7 Lactobacillaceae 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1V1ET@1239,3F71I@33958,4HGNA@91061,COG3290@1,COG3290@2 NA|NA|NA T GHKL domain GHBLAFEN_00635 405566.lhv_0631 2.6e-160 571.2 Lactobacillaceae rssA Bacteria 1TQ9W@1239,3F52H@33958,4HCHJ@91061,COG4667@1,COG4667@2 NA|NA|NA S Phospholipase, patatin family GHBLAFEN_00636 405566.lhv_0629 0.0 1675.2 Lactobacillaceae xfp 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 Bacteria 1TR23@1239,3F3TZ@33958,4HC2J@91061,COG3957@1,COG3957@2 NA|NA|NA G Phosphoketolase GHBLAFEN_00637 405566.lhv_0628 1.4e-131 475.7 Lactobacillaceae glcR ko:K02444,ko:K22103 ko00000,ko03000 Bacteria 1V1VH@1239,3F3UT@33958,4HG12@91061,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain GHBLAFEN_00638 326425.lhe_0563 5.4e-62 243.4 Lactobacillaceae Bacteria 1U639@1239,29P3Y@1,30A25@2,3F6XR@33958,4IFSM@91061 NA|NA|NA S Enterocin A Immunity GHBLAFEN_00639 405566.lhv_0626 6.2e-54 216.5 Lactobacillaceae yitW ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1V9YV@1239,3F7D5@33958,4HKC6@91061,COG2151@1,COG2151@2 NA|NA|NA S Iron-sulfur cluster assembly protein GHBLAFEN_00640 525365.HMPREF0548_0635 1.9e-272 944.5 Lactobacillaceae sufB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 ko:K07033,ko:K09014 ko00000 Bacteria 1TQ21@1239,3F44I@33958,4HA1Z@91061,COG0719@1,COG0719@2 NA|NA|NA O assembly protein SufB GHBLAFEN_00641 326425.lhe_0560 4.2e-80 303.9 Lactobacillaceae nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 ko:K04488 ko00000 Bacteria 1V3H9@1239,3F6WP@33958,4HIJ0@91061,COG0822@1,COG0822@2 NA|NA|NA C SUF system FeS assembly protein, NifU family GHBLAFEN_00642 405566.lhv_0623 1.5e-236 825.1 Lactobacillaceae sufS 2.8.1.7,4.4.1.16 ko:K04487,ko:K11717 ko00450,ko00730,ko01100,ko04122,map00450,map00730,map01100,map04122 R03599,R07460,R11528,R11529 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TQ1W@1239,3F3UP@33958,4HA6Z@91061,COG0520@1,COG0520@2 NA|NA|NA E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine GHBLAFEN_00643 405566.lhv_0622 1.2e-225 788.9 Lactobacillaceae sufD ko:K07033,ko:K09015 ko00000 Bacteria 1TRT0@1239,3F4BR@33958,4HB6W@91061,COG0719@1,COG0719@2 NA|NA|NA O FeS assembly protein SufD GHBLAFEN_00644 405566.lhv_0621 2.2e-145 521.5 Lactobacillaceae sufC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 ko:K09013 ko00000,ko02000 iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710 Bacteria 1TQ98@1239,3F3XT@33958,4HAD9@91061,COG0396@1,COG0396@2 NA|NA|NA O FeS assembly ATPase SufC GHBLAFEN_00645 326425.lhe_1229 2.2e-55 221.5 Lactobacillaceae Bacteria 1UYIX@1239,3F5K8@33958,4HF6W@91061,COG2887@1,COG2887@2 NA|NA|NA L AAA domain GHBLAFEN_00646 405566.lhv_0178 8.7e-43 179.1 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TT4J@1239,3FB6R@33958,4IRBE@91061,COG0675@1,COG0675@2 NA|NA|NA L Probable transposase GHBLAFEN_00647 326425.lhe_1242 6.9e-37 159.5 Lactobacillaceae Bacteria 1TPE1@1239,3F3NJ@33958,4HA65@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family GHBLAFEN_00648 908339.HMPREF9265_1394 5e-23 113.6 Lactobacillaceae repA Bacteria 1VHQA@1239,2DP1C@1,3304N@2,3F55E@33958,4HPY6@91061 NA|NA|NA S Replication initiator protein A GHBLAFEN_00649 326425.lhe_1264 3.9e-199 700.7 Lactobacillaceae dnaJ ko:K03686 ko00000,ko03029,ko03110 Bacteria 1TP00@1239,3F490@33958,4H9KA@91061,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins GHBLAFEN_00650 405566.lhv_1336 0.0 1120.1 Lactobacillaceae dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 1TP1J@1239,3F48C@33958,4HA9S@91061,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein GHBLAFEN_00651 1423748.BALB01000013_gene1286 8.2e-81 306.6 Lactobacillaceae grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 ko:K03687 ko00000,ko03029,ko03110 Bacteria 1V6G2@1239,3F4DY@33958,4HIRK@91061,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ GHBLAFEN_00652 326425.lhe_1267 4.5e-186 657.1 Lactobacillaceae hrcA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K03705 ko00000,ko03000 Bacteria 1TQP7@1239,3F3ST@33958,4HAX5@91061,COG1420@1,COG1420@2 NA|NA|NA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons GHBLAFEN_00653 405566.lhv_1339 2.3e-181 641.3 Lactobacillaceae ribF 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS06310 Bacteria 1TPKS@1239,3F3TG@33958,4H9KE@91061,COG0196@1,COG0196@2 NA|NA|NA H Belongs to the ribF family GHBLAFEN_00654 405566.lhv_1340 9.8e-166 589.3 Lactobacillaceae truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 ko00000,ko01000,ko03000,ko03016 iSB619.SA_RS06305 Bacteria 1TP9Y@1239,3F3NX@33958,4HA9X@91061,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs GHBLAFEN_00655 405566.lhv_1341 3.3e-59 234.2 Lactobacillaceae rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 ko:K02834 ko00000,ko03009 Bacteria 1VA0P@1239,3F6WZ@33958,4HII1@91061,COG0858@1,COG0858@2 NA|NA|NA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA GHBLAFEN_00656 326425.lhe_1271 0.0 1398.3 Lactobacillaceae infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K02519 ko00000,ko03012,ko03029 Bacteria 1TPAI@1239,3F3JV@33958,4HA8S@91061,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex GHBLAFEN_00657 326425.lhe_1272 1e-45 189.1 Lactobacillaceae rplGA ko:K07590,ko:K07742 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEYG@1239,3F7ZK@33958,4HNY7@91061,COG1358@1,COG1358@2 NA|NA|NA J ribosomal protein GHBLAFEN_00658 405566.lhv_1345 4.6e-195 687.2 Lactobacillaceae nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02600,ko:K02945 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03009,ko03011,ko03021 Bacteria 1TPB3@1239,3F3KZ@33958,4HA7F@91061,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination GHBLAFEN_00659 405566.lhv_1346 5.5e-83 313.5 Lactobacillaceae rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 ko:K09748 ko00000,ko03009 Bacteria 1V6KT@1239,3F6GZ@33958,4HH88@91061,COG0779@1,COG0779@2 NA|NA|NA J Required for maturation of 30S ribosomal subunits GHBLAFEN_00660 326425.lhe_1276 0.0 2865.1 Lactobacillaceae polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K02342,ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPAG@1239,3F4AN@33958,4H9RF@91061,COG2176@1,COG2176@2 NA|NA|NA L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity GHBLAFEN_00661 326425.lhe_1277 0.0 1119.8 Lactobacillaceae proS GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iJN678.proS,iUTI89_1310.UTI89_C0210 Bacteria 1TRBV@1239,3F44A@33958,4H9NN@91061,COG0442@1,COG0442@2 NA|NA|NA J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS GHBLAFEN_00662 326425.lhe_1278 8.8e-197 693.0 Lactobacillaceae rseP GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107,3.4.21.116 ko:K04771,ko:K06399,ko:K11749,ko:K16922 ko01503,ko02020,ko02024,ko04112,map01503,map02020,map02024,map04112 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1TPMC@1239,3F3TM@33958,4HAQ5@91061,COG0750@1,COG0750@2 NA|NA|NA M zinc metalloprotease GHBLAFEN_00663 326425.lhe_1279 1.6e-146 525.4 Lactobacillaceae cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1397 Bacteria 1UPNB@1239,3F4AF@33958,4IV81@91061,COG0575@1,COG0575@2 NA|NA|NA I Belongs to the CDS family GHBLAFEN_00664 326425.lhe_1280 7.8e-137 493.0 Lactobacillaceae uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 Bacteria 1TQTS@1239,3F42M@33958,4HA37@91061,COG0020@1,COG0020@2 NA|NA|NA H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids GHBLAFEN_00665 405566.lhv_1353 3.4e-92 344.4 Lactobacillaceae frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02838 ko00000,ko03012 Bacteria 1V1F2@1239,3F4X2@33958,4HFSH@91061,COG0233@1,COG0233@2 NA|NA|NA J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another GHBLAFEN_00666 1423748.BALB01000013_gene1269 7e-130 469.9 Lactobacillaceae pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 iSB619.SA_RS06240 Bacteria 1TPXN@1239,3F42J@33958,4H9UB@91061,COG0528@1,COG0528@2 NA|NA|NA F Catalyzes the reversible phosphorylation of UMP to UDP GHBLAFEN_00667 326425.lhe_1283 3.1e-184 651.0 Lactobacillaceae tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 ko:K02357 ko00000,ko03012,ko03029 Bacteria 1TPFJ@1239,3F459@33958,4HBDV@91061,COG0264@1,COG0264@2 NA|NA|NA J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome GHBLAFEN_00668 326425.lhe_1284 1.2e-140 505.8 Lactobacillaceae rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPNA@1239,3F3M1@33958,4H9N5@91061,COG0052@1,COG0052@2 NA|NA|NA J Belongs to the universal ribosomal protein uS2 family GHBLAFEN_00669 326425.lhe_1285 1.7e-198 698.4 Lactobacillaceae yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 ko00000,ko01000,ko03016 Bacteria 1TQ25@1239,3F4C5@33958,4HA8W@91061,COG2827@1,COG2827@2,COG4123@1,COG4123@2 NA|NA|NA L Methyltransferase small domain GHBLAFEN_00670 326425.lhe_1286 5.1e-113 413.7 Lactobacillaceae plsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1U8N2@1239,3F4QB@33958,4HDQR@91061,COG0204@1,COG0204@2 NA|NA|NA I Acyltransferase GHBLAFEN_00671 353496.LBU_1254 3.2e-225 787.3 Lactobacillaceae cfa 2.1.1.317,2.1.1.79 ko:K00574,ko:K20238 ko00000,ko01000 Bacteria 1TSG4@1239,3F3PA@33958,4HDKI@91061,COG2230@1,COG2230@2 NA|NA|NA M cyclopropane-fatty-acyl-phospholipid synthase GHBLAFEN_00672 405566.lhv_1360 0.0 1300.4 Lactobacillaceae pepO 3.4.24.71 ko:K01415,ko:K07386 ko00000,ko01000,ko01002,ko04147 Bacteria 1TQTA@1239,3F4CX@33958,4HDSF@91061,COG3590@1,COG3590@2 NA|NA|NA O Peptidase family M13 GHBLAFEN_00673 1423767.BALU01000005_gene968 1.2e-300 1038.5 Lactobacillaceae mdlB GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008144,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0033036,GO:0034040,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K06147,ko:K18890 ko02010,map02010 M00707 ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter GHBLAFEN_00674 748671.LCRIS_01291 1e-296 1025.4 Lactobacillaceae mdlA GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016021,GO:0017076,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K06148,ko:K18889 ko02010,map02010 M00707 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter GHBLAFEN_00675 405566.lhv_1362 4.2e-30 136.7 Lactobacillaceae yneF ko:K09976 ko00000 Bacteria 1VEJC@1239,3F809@33958,4HKMJ@91061,COG3763@1,COG3763@2 NA|NA|NA S Uncharacterised protein family (UPF0154) GHBLAFEN_00676 1423748.BALB01000030_gene1892 4.3e-37 160.2 Lactobacillaceae ynzC Bacteria 1VEKJ@1239,3F87S@33958,4HNIB@91061,COG4224@1,COG4224@2 NA|NA|NA S UPF0291 protein GHBLAFEN_00677 405566.lhv_1364 1.5e-112 412.1 Lactobacillaceae lexA 3.4.21.88 ko:K01356 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 1TQ3H@1239,3F3JG@33958,4HBHA@91061,COG1974@1,COG1974@2 NA|NA|NA K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair GHBLAFEN_00678 326425.lhe_1294 2.1e-148 531.6 Lactobacillaceae Bacteria 1V4VT@1239,3F4P8@33958,4HXCK@91061,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase family GHBLAFEN_00679 405566.lhv_1366 9.2e-121 439.5 Lactobacillaceae ung2 3.2.2.27 ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V4M9@1239,3F4GW@33958,4HHJN@91061,COG1573@1,COG1573@2 NA|NA|NA L Uracil-DNA glycosylase GHBLAFEN_00680 1423748.BALB01000030_gene1896 1.1e-56 225.7 Lactobacillaceae rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6FT@1239,3F6K4@33958,4HIK3@91061,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site GHBLAFEN_00681 405566.lhv_1369 1.7e-136 491.9 Lactobacillaceae trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1TPBV@1239,3F3NP@33958,4HBFV@91061,COG0336@1,COG0336@2 NA|NA|NA J Belongs to the RNA methyltransferase TrmD family GHBLAFEN_00682 326425.lhe_1298 4.1e-92 344.0 Lactobacillaceae rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 ko:K02860 ko00000,ko03009 Bacteria 1V6HD@1239,3F74P@33958,4HH3H@91061,COG0806@1,COG0806@2 NA|NA|NA J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes GHBLAFEN_00683 1033837.WANG_0417 4.5e-45 186.8 Lactobacillaceae rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VA0X@1239,3F6VV@33958,4HKNN@91061,COG0228@1,COG0228@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS16 family GHBLAFEN_00684 326425.lhe_1300 1.9e-227 795.0 Lactobacillaceae ffh GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 1TP06@1239,3F40R@33958,4H9T4@91061,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY GHBLAFEN_00685 326425.lhe_1301 3.2e-56 224.2 Lactobacillaceae ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 ko:K09787 ko00000 Bacteria 1VEGP@1239,3F7FG@33958,4HKK6@91061,COG2739@1,COG2739@2 NA|NA|NA S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein GHBLAFEN_00686 1033837.WANG_p1034 1.7e-193 681.8 Lactobacillaceae Bacteria 1TRSF@1239,3F3YG@33958,4HADR@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family GHBLAFEN_00687 326425.lhe_1302 5.4e-259 899.8 Lactobacillaceae yfnA ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3FCAJ@33958,4HA32@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid GHBLAFEN_00688 1423748.BALB01000030_gene1903 1.8e-44 185.3 Lactobacillaceae Bacteria 1U68Z@1239,29P84@1,30A66@2,3F7C1@33958,4IG04@91061 NA|NA|NA GHBLAFEN_00689 326425.lhe_1304 1.7e-289 1001.1 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase GHBLAFEN_00690 326425.lhe_1305 4.9e-166 590.9 Lactobacillaceae ftsY ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 1TPRI@1239,3F3YC@33958,4HA6A@91061,COG0552@1,COG0552@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) GHBLAFEN_00691 405566.lhv_1379 0.0 1364.0 Lactobacillaceae smc ko:K03529 ko00000,ko03036 Bacteria 1TPJV@1239,3F478@33958,4HB89@91061,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning GHBLAFEN_00692 326425.lhe_1307 1.3e-125 455.7 Lactobacillaceae rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 1TPGC@1239,3F564@33958,4HAWU@91061,COG0571@1,COG0571@2 NA|NA|NA J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism GHBLAFEN_00693 525365.HMPREF0548_0850 0.0 1077.0 Lactobacillaceae oppA ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1TQ0N@1239,3F3KW@33958,4HARF@91061,COG0747@1,COG0747@2 NA|NA|NA E ABC transporter substrate-binding protein GHBLAFEN_00694 405566.lhv_2929 0.0 1151.3 Lactobacillaceae oppA ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1TQ0N@1239,3F3KW@33958,4HARF@91061,COG0747@1,COG0747@2 NA|NA|NA E ABC transporter substrate-binding protein GHBLAFEN_00695 326425.lhe_1310 1.9e-143 515.4 Lactobacillaceae oppC ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP4R@1239,3FCB7@33958,4HDIR@91061,COG1173@1,COG1173@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component GHBLAFEN_00696 1033837.WANG_0407 6.6e-176 623.2 Lactobacillaceae oppB ko:K02033,ko:K02034,ko:K13894 ko02010,ko02024,map02010,map02024 M00239,M00349 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 Bacteria 1TP1S@1239,3FCCU@33958,4HATR@91061,COG0601@1,COG0601@2 NA|NA|NA P ABC transporter permease GHBLAFEN_00697 326425.lhe_1312 1.2e-180 639.0 Lactobacillaceae oppF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02032,ko:K10823,ko:K12372,ko:K13892 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00324,M00348,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.11,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1V36J@1239,3F4GM@33958,4H9YB@91061,COG4608@1,COG4608@2 NA|NA|NA P Belongs to the ABC transporter superfamily GHBLAFEN_00698 405566.lhv_1391 1.7e-193 681.8 Lactobacillaceae oppD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP6E@1239,3F41T@33958,4HA4E@91061,COG0444@1,COG0444@2 NA|NA|NA P Belongs to the ABC transporter superfamily GHBLAFEN_00699 326425.lhe_1314 9.8e-36 155.6 Lactobacillaceae acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 1VEE3@1239,3F7F4@33958,4HNQ0@91061,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis GHBLAFEN_00700 405566.lhv_1393 2.9e-182 644.4 Lactobacillaceae plsX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPXS@1239,3F4N9@33958,4HA0R@91061,COG0416@1,COG0416@2 NA|NA|NA I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA GHBLAFEN_00701 326425.lhe_1316 0.0 1315.4 Lactobacillaceae recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TQ6I@1239,3F3JW@33958,4HAWN@91061,COG1200@1,COG1200@2 NA|NA|NA L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) GHBLAFEN_00702 326425.lhe_1317 2.2e-304 1050.8 Lactobacillaceae yloV ko:K07030 ko00000 Bacteria 1TQMX@1239,3F3X0@33958,4HBSE@91061,COG1461@1,COG1461@2 NA|NA|NA S DAK2 domain fusion protein YloV GHBLAFEN_00703 1423748.BALB01000011_gene1141 6.8e-57 226.5 Lactobacillaceae asp Bacteria 1V731@1239,3F72W@33958,4HIS4@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function GHBLAFEN_00704 525365.HMPREF0548_0839 2.4e-26 124.0 Lactobacillaceae rpmB GO:0003674,GO:0003735,GO:0005198 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEI2@1239,3F7ZN@33958,4HNIK@91061,COG0227@1,COG0227@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL28 family GHBLAFEN_00705 405566.lhv_1398 5.7e-49 199.9 Lactobacillaceae Bacteria 1U65W@1239,2AE84@1,31424@2,3F756@33958,4IFVX@91061 NA|NA|NA GHBLAFEN_00706 405566.lhv_1399 7.6e-126 456.4 Lactobacillaceae thiN 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 R00619 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1VA0W@1239,3F4N8@33958,4HHS1@91061,COG1564@1,COG1564@2 NA|NA|NA H thiamine pyrophosphokinase GHBLAFEN_00707 326425.lhe_1322 9.4e-118 429.5 Lactobacillaceae rpe 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQK8@1239,3F4KX@33958,4H9RW@91061,COG0036@1,COG0036@2 NA|NA|NA G Belongs to the ribulose-phosphate 3-epimerase family GHBLAFEN_00708 405566.lhv_1401 1.7e-165 588.6 Lactobacillaceae rsgA 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 Bacteria 1TPSQ@1239,3F3XH@33958,4HA9W@91061,COG1162@1,COG1162@2 NA|NA|NA S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit GHBLAFEN_00709 326425.lhe_1324 0.0 1145.6 Lactobacillaceae prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 1TP3F@1239,3F4G6@33958,4H9KD@91061,COG0515@1,COG0515@2,COG2815@1,COG2815@2 NA|NA|NA KLT serine threonine protein kinase GHBLAFEN_00710 326425.lhe_1325 9.2e-147 526.2 Lactobacillaceae stp 3.1.3.16 ko:K20074 ko00000,ko01000,ko01009 Bacteria 1V6K5@1239,3F4UI@33958,4HCDR@91061,COG0631@1,COG0631@2 NA|NA|NA T phosphatase GHBLAFEN_00711 405566.lhv_1404 4.1e-245 853.6 Lactobacillaceae sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 1TP3N@1239,3F45F@33958,4HBQ6@91061,COG0144@1,COG0144@2,COG0781@1,COG0781@2 NA|NA|NA J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA GHBLAFEN_00712 405566.lhv_1405 3e-173 614.4 Lactobacillaceae fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000 iSB619.SA_RS06010 Bacteria 1TQ32@1239,3F4N7@33958,4HART@91061,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus GHBLAFEN_00713 405566.lhv_1406 0.0 1576.2 Lactobacillaceae priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TNYB@1239,3F3N8@33958,4H9WW@91061,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA GHBLAFEN_00714 1423748.BALB01000011_gene1155 9.4e-33 145.6 Lactobacillaceae rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1VK74@1239,3F81N@33958,4HNHS@91061,COG1758@1,COG1758@2 NA|NA|NA K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits GHBLAFEN_00715 1423748.BALB01000011_gene1156 1.2e-109 402.5 Lactobacillaceae gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 ko:K00942,ko:K01591 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00050,M00051 R00332,R00965,R02090 RC00002,RC00409 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_2813,iIT341.HP0321,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193,iYO844.BSU15680 Bacteria 1TP0M@1239,3F3X9@33958,4HAYW@91061,COG0194@1,COG0194@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP GHBLAFEN_00716 405566.lhv_1409 1.7e-78 298.5 Lactobacillaceae 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 Bacteria 1V6S0@1239,3F7EV@33958,4HKKR@91061,COG4405@1,COG4405@2 NA|NA|NA S ASCH GHBLAFEN_00717 405566.lhv_1410 1.8e-306 1057.7 Lactobacillaceae recN GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 ko:K03631,ko:K13582 ko04112,map04112 ko00000,ko00001,ko03400 Bacteria 1TP99@1239,3F43U@33958,4H9ZR@91061,COG0497@1,COG0497@2 NA|NA|NA L May be involved in recombinational repair of damaged DNA GHBLAFEN_00718 326425.lhe_1333 2.3e-150 538.1 Lactobacillaceae rrmJ 2.1.1.226,2.1.1.227 ko:K06442 ko00000,ko01000,ko03009 Bacteria 1TPE4@1239,3F45T@33958,4HAPY@91061,COG1189@1,COG1189@2 NA|NA|NA J Ribosomal RNA large subunit methyltransferase J GHBLAFEN_00719 326425.lhe_1334 2.3e-156 558.1 Lactobacillaceae ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 ko:K00795,ko:K02523,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061,R09248 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1TPQY@1239,3F436@33958,4HA8E@91061,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family GHBLAFEN_00720 1423748.BALB01000011_gene1162 2.9e-35 154.1 Lactobacillaceae xseB 3.1.11.6 ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1VK9I@1239,3F81K@33958,4HNRB@91061,COG1722@1,COG1722@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides GHBLAFEN_00721 405566.lhv_1414 1.5e-194 685.6 Lactobacillaceae xseA 3.1.11.6 ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP4E@1239,3F4RE@33958,4HAN2@91061,COG1570@1,COG1570@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides GHBLAFEN_00722 405566.lhv_1415 4e-153 547.4 Lactobacillaceae folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1P@1239,3F46A@33958,4H9Q6@91061,COG0190@1,COG0190@2 NA|NA|NA F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate GHBLAFEN_00723 326425.lhe_1339 1.4e-63 248.8 Lactobacillaceae nusB ko:K03625 ko00000,ko03009,ko03021 Bacteria 1VA9B@1239,3F7KW@33958,4HKMU@91061,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons GHBLAFEN_00724 405566.lhv_1420 5.3e-69 266.9 Lactobacillaceae yqhY ko:K10947 ko00000,ko03000 Bacteria 1V4IC@1239,3F71X@33958,4HJ7T@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function GHBLAFEN_00725 1423748.BALB01000011_gene1167 9.2e-101 372.9 Lactobacillaceae efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 1TR8P@1239,3F422@33958,4H9YX@91061,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase GHBLAFEN_00726 405566.lhv_1422 7.5e-200 703.0 Lactobacillaceae pepP 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 ko00000,ko01000,ko01002 Bacteria 1TQ44@1239,3F4DR@33958,4HAT7@91061,COG0006@1,COG0006@2 NA|NA|NA E Creatinase/Prolidase N-terminal domain GHBLAFEN_00727 1423748.BALB01000011_gene1169 1e-47 195.7 Lactobacillaceae rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6HW@1239,3F6WU@33958,4HIMN@91061,COG0211@1,COG0211@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL27 family GHBLAFEN_00728 1423748.BALB01000011_gene1170 5.8e-49 199.9 Lactobacillaceae rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9YH@1239,3F6WT@33958,4HIGK@91061,COG0261@1,COG0261@2 NA|NA|NA J This protein binds to 23S rRNA in the presence of protein L20 GHBLAFEN_00729 326425.lhe_1345 9.1e-256 889.0 Lactobacillaceae Bacteria 1VK4A@1239,2EM25@1,33ERN@2,3F53P@33958,4HRGD@91061 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2325) GHBLAFEN_00730 326425.lhe_0946 0.0 1198.0 Lactobacillaceae uvrC ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TP4B@1239,3F3MY@33958,4H9QH@91061,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision GHBLAFEN_00731 326425.lhe_0947 1.4e-242 845.1 Lactobacillaceae obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043021,GO:0043022,GO:0043167,GO:0043168,GO:0043934,GO:0044424,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03979 ko00000,ko01000,ko03009 Bacteria 1TPX7@1239,3F4ZA@33958,4H9P8@91061,COG0536@1,COG0536@2 NA|NA|NA S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control GHBLAFEN_00732 405566.lhv_1042 0.0 1151.0 Lactobacillaceae oatA Bacteria 1TPTG@1239,3F3WT@33958,4HB7R@91061,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase GHBLAFEN_00733 405566.lhv_1043 6.8e-178 629.8 Lactobacillaceae rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 1TRGP@1239,3F4F1@33958,4HABM@91061,COG1234@1,COG1234@2 NA|NA|NA J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA GHBLAFEN_00734 405566.lhv_1044 6.1e-143 513.5 Lactobacillaceae XK27_05435 1.1.1.100 ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TSJ3@1239,3F41Y@33958,4HI3D@91061,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family GHBLAFEN_00735 326425.lhe_0951 6.2e-33 146.4 Lactobacillaceae yrvD ko:K08992 ko00000 Bacteria 1VIG5@1239,3F7IW@33958,4HP5V@91061,COG5416@1,COG5416@2 NA|NA|NA S Lipopolysaccharide assembly protein A domain GHBLAFEN_00736 1423748.BALB01000010_gene1125 7.6e-28 129.0 Lactobacillaceae rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VKMZ@1239,3F7ZT@33958,4HR2Q@91061,COG0333@1,COG0333@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL32 family GHBLAFEN_00737 326425.lhe_0953 1.5e-307 1061.2 Lactobacillaceae cpdB 3.1.3.6,3.1.4.16 ko:K01119 ko00230,ko00240,map00230,map00240 R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135 RC00078,RC00296 ko00000,ko00001,ko01000 Bacteria 1TPV2@1239,3F45U@33958,4HC2M@91061,COG0737@1,COG0737@2 NA|NA|NA F Belongs to the 5'-nucleotidase family GHBLAFEN_00738 326425.lhe_0954 2.5e-22 110.9 Lactobacillaceae Bacteria 1U6JJ@1239,29PGH@1,30AEN@2,3F81E@33958,4IGC1@91061 NA|NA|NA S Protein of unknown function (DUF2929) GHBLAFEN_00739 326425.lhe_0955 0.0 1967.6 Lactobacillaceae dnaE 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPYG@1239,3F4AM@33958,4H9T3@91061,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase GHBLAFEN_00740 405566.lhv_1049 6.6e-184 649.8 Lactobacillaceae pfkA GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 iYO844.BSU29190 Bacteria 1TPF4@1239,3F4CC@33958,4HAPN@91061,COG0205@1,COG0205@2 NA|NA|NA F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis GHBLAFEN_00741 326425.lhe_0957 0.0 1127.1 Lactobacillaceae pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009986,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0022607,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40,2.7.7.4 ko:K00873,ko:K00958 ko00010,ko00230,ko00261,ko00450,ko00620,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00261,map00450,map00620,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050,M00176,M00596 R00200,R00430,R00529,R01138,R01858,R02320,R04929 RC00002,RC00015,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iECO103_1326.ECO103_1819,iPC815.YPO2393 Bacteria 1TPGG@1239,3F3JU@33958,4H9VY@91061,COG0469@1,COG0469@2 NA|NA|NA G Belongs to the pyruvate kinase family GHBLAFEN_00742 405566.lhv_1051 5.5e-169 600.1 Lactobacillaceae cvfB ko:K00243 ko00000 Bacteria 1TQ1Z@1239,3F44W@33958,4HDAZ@91061,COG2996@1,COG2996@2 NA|NA|NA S S1 domain GHBLAFEN_00743 326425.lhe_0959 4e-167 594.0 Lactobacillaceae xerD ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 1TQRG@1239,3F3V9@33958,4HAEX@91061,COG4974@1,COG4974@2 NA|NA|NA D recombinase XerD GHBLAFEN_00744 326425.lhe_0960 4.9e-60 236.9 Lactobacillaceae ribT ko:K02859 ko00000 Bacteria 1VAD7@1239,3F7QC@33958,4HKR2@91061,COG0454@1,COG0456@2 NA|NA|NA K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases GHBLAFEN_00745 405566.lhv_1054 7.2e-130 469.9 Lactobacillaceae scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K05896 ko00000,ko03036 Bacteria 1TRW3@1239,3F4FS@33958,4HA6Q@91061,COG1354@1,COG1354@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves GHBLAFEN_00746 405566.lhv_1055 9.2e-104 382.9 Lactobacillaceae scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K06024 ko00000,ko03036 Bacteria 1V6HI@1239,3F5RN@33958,4HIQ0@91061,COG1386@1,COG1386@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves GHBLAFEN_00747 326425.lhe_0963 8.5e-128 463.0 Lactobacillaceae rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.21,5.4.99.22 ko:K06178,ko:K06182,ko:K06183 ko00000,ko01000,ko03009 Bacteria 1TP68@1239,3F402@33958,4H9MU@91061,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family GHBLAFEN_00748 405566.lhv_1057 1.2e-115 422.5 Lactobacillaceae Bacteria 1V4BW@1239,3F4HD@33958,4HHFT@91061,COG3601@1,COG3601@2 NA|NA|NA U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins GHBLAFEN_00749 405566.lhv_1059 3.4e-29 134.8 Lactobacillaceae yocH Bacteria 1W2PN@1239,3F6G9@33958,4I0F8@91061,COG1388@1,COG1388@2 NA|NA|NA M Lysin motif GHBLAFEN_00750 326425.lhe_0966 4.5e-115 420.6 Lactobacillaceae cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.17.7.4,2.5.1.19,2.7.1.26,2.7.4.25,2.7.7.2,6.3.2.1 ko:K00800,ko:K00945,ko:K02945,ko:K03527,ko:K03977,ko:K11753,ko:K13799 ko00240,ko00400,ko00410,ko00740,ko00770,ko00900,ko01100,ko01110,ko01130,ko01230,ko03010,map00240,map00400,map00410,map00740,map00770,map00900,map01100,map01110,map01130,map01230,map03010 M00022,M00052,M00096,M00119,M00125,M00178 R00158,R00161,R00512,R00549,R01665,R02473,R03460,R05884,R08210 RC00002,RC00017,RC00096,RC00141,RC00350,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03009,ko03011 iPC815.YPO1391,iSDY_1059.SDY_2348 Bacteria 1V3IA@1239,3F3W4@33958,4HFZE@91061,COG0283@1,COG0283@2 NA|NA|NA F Belongs to the cytidylate kinase family. Type 1 subfamily GHBLAFEN_00751 326425.lhe_0967 9.1e-207 726.1 Lactobacillaceae rpsA 1.17.7.4 ko:K02945,ko:K03527 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 Bacteria 1TQ9N@1239,3F4DQ@33958,4H9PX@91061,COG0539@1,COG0539@2 NA|NA|NA J Ribosomal protein S1 GHBLAFEN_00752 326425.lhe_0968 1.1e-245 855.5 Lactobacillaceae der GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.399,1.1.1.95 ko:K00058,ko:K03977 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 Bacteria 1TPNM@1239,3F4V0@33958,4HAJ6@91061,COG1160@1,COG1160@2 NA|NA|NA S GTPase that plays an essential role in the late steps of ribosome biogenesis GHBLAFEN_00753 1423748.BALB01000009_gene1004 3.9e-41 173.7 Lactobacillaceae hup ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 1V9XQ@1239,3F6YN@33958,4HKF2@91061,COG0776@1,COG0776@2 NA|NA|NA L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions GHBLAFEN_00754 405566.lhv_1064 4.3e-228 797.0 Lactobacillaceae Bacteria 1TT97@1239,3F3ND@33958,4HAIA@91061,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat protein GHBLAFEN_00755 326425.lhe_0971 1.1e-158 565.8 Lactobacillaceae ypjC Bacteria 1TR9J@1239,3FC4M@33958,4H9N6@91061,COG1284@1,COG1284@2 NA|NA|NA S Uncharacterised 5xTM membrane BCR, YitT family COG1284 GHBLAFEN_00756 405566.lhv_1066 7.8e-227 792.7 Lactobacillaceae cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 1TQ2A@1239,3F3VH@33958,4HB2W@91061,COG0617@1,COG0617@2 NA|NA|NA J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate GHBLAFEN_00757 405566.lhv_1877 1.8e-275 954.5 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase GHBLAFEN_00758 326425.lhe_0342 8e-38 162.5 Lactobacillaceae Bacteria 1U6B2@1239,2A5EV@1,30U4Q@2,3F7HR@33958,4IG2J@91061 NA|NA|NA GHBLAFEN_00759 405566.lhv_1873 3.1e-110 404.4 Lactobacillaceae Bacteria 1U9UE@1239,3F403@33958,4HM7U@91061,COG1309@1,COG1309@2 NA|NA|NA K WHG domain GHBLAFEN_00760 326425.lhe_0345 1.9e-95 355.1 Lactobacillaceae nqr 1.5.1.36 ko:K22393,ko:K22394 ko00740,ko01100,map00740,map01100 R05705,R09748,R09750 RC00126 ko00000,ko00001,ko01000 Bacteria 1VI8F@1239,3FCC2@33958,4HPT0@91061,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase GHBLAFEN_00761 326425.lhe_0346 3.5e-97 360.9 Lactobacillaceae azr 1.5.1.36 ko:K22393,ko:K22394 ko00740,ko01100,map00740,map01100 R05705,R09748,R09750 RC00126 ko00000,ko00001,ko01000 Bacteria 1TT2S@1239,3F544@33958,4HBQI@91061,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase GHBLAFEN_00762 405566.lhv_1870 2.8e-148 531.2 Lactobacillaceae 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1VA24@1239,3F4H4@33958,4IQXZ@91061,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family GHBLAFEN_00763 326425.lhe_0348 2.8e-179 634.4 Lactobacillaceae apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 1TR9C@1239,3F3QR@33958,4HHVC@91061,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein GHBLAFEN_00764 1423748.BALB01000012_gene1237 7.3e-84 316.6 Lactobacillaceae cvpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 ko:K03558 ko00000 Bacteria 1U58E@1239,3F552@33958,4IEZI@91061,COG1286@1,COG1286@2 NA|NA|NA S Colicin V production protein GHBLAFEN_00765 326425.lhe_0350 1.8e-130 471.9 Lactobacillaceae rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 ko00000,ko01000,ko03009,ko03036 Bacteria 1TPBT@1239,3F3ZX@33958,4HAAZ@91061,COG0357@1,COG0357@2 NA|NA|NA J Specifically methylates the N7 position of a guanine in 16S rRNA GHBLAFEN_00766 326425.lhe_0351 3.9e-148 530.8 Lactobacillaceae noc ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 1TP0I@1239,3F4RU@33958,4HAC6@91061,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family GHBLAFEN_00767 326425.lhe_0352 1.9e-136 491.9 Lactobacillaceae soj ko:K03496 ko00000,ko03036,ko04812 Bacteria 1TP8S@1239,3F4AE@33958,4HAYM@91061,COG1192@1,COG1192@2 NA|NA|NA D Sporulation initiation inhibitor GHBLAFEN_00768 405566.lhv_1864 8.5e-154 549.7 Lactobacillaceae spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 1TQ2B@1239,3F47R@33958,4H9TB@91061,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family GHBLAFEN_00769 326425.lhe_0354 8.1e-44 182.6 Lactobacillaceae yyzM Bacteria 1VEQ7@1239,3F823@33958,4HNHU@91061,COG4481@1,COG4481@2 NA|NA|NA S Bacterial protein of unknown function (DUF951) GHBLAFEN_00770 326425.lhe_0355 6.1e-202 709.9 Lactobacillaceae ychF GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 ko:K06942 ko00000,ko03009 Bacteria 1TPRK@1239,3F3TK@33958,4H9SQ@91061,COG0012@1,COG0012@2 NA|NA|NA J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner GHBLAFEN_00771 326425.lhe_0356 2e-138 498.4 Lactobacillaceae XK27_01040 Bacteria 1VF5N@1239,3F4JS@33958,4HH7B@91061,COG4858@1,COG4858@2 NA|NA|NA S Protein of unknown function (DUF1129) GHBLAFEN_00772 326425.lhe_0357 3.5e-297 1026.9 Lactobacillaceae ko:K06147,ko:K06148,ko:K18891 ko02010,map02010 M00708 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 Bacteria 1TP0B@1239,3F3SP@33958,4H9SC@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter, ATP-binding protein GHBLAFEN_00773 326425.lhe_0358 0.0 1172.5 Lactobacillaceae ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter GHBLAFEN_00774 405566.lhv_1855 5.1e-122 443.7 Lactobacillaceae Bacteria 1TP9M@1239,3F3Y0@33958,4HB3T@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator GHBLAFEN_00775 326425.lhe_0360 9.2e-209 732.6 Lactobacillaceae hpk31 2.7.13.3 ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TRZ0@1239,3FC2N@33958,4H9U1@91061,COG5002@1,COG5002@2 NA|NA|NA T His Kinase A (phospho-acceptor) domain GHBLAFEN_00776 326425.lhe_0361 3.2e-305 1053.5 Lactobacillaceae murE 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 Bacteria 1TPQE@1239,3F3UE@33958,4H9T1@91061,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan GHBLAFEN_00777 405566.lhv_1852 7.2e-146 523.1 Lactobacillaceae racD 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 R00491 RC00302 ko00000,ko00001,ko01000 Bacteria 1TQ6M@1239,3FCEP@33958,4HR12@91061,COG1794@1,COG1794@2 NA|NA|NA M Belongs to the aspartate glutamate racemases family GHBLAFEN_00778 1033837.WANG_1166 1.4e-211 742.3 Lactobacillaceae ko:K06921 ko00000 Bacteria 1TR21@1239,3F57U@33958,4HF7F@91061,COG1672@1,COG1672@2 NA|NA|NA S Archaea bacterial proteins of unknown function GHBLAFEN_00779 405566.lhv_1850 6.7e-28 129.4 Lactobacillaceae Bacteria 1U65A@1239,29P5G@1,30A3N@2,3F737@33958,4IFV3@91061 NA|NA|NA S Enterocin A Immunity GHBLAFEN_00780 405566.lhv_1849 1.9e-33 147.9 Lactobacillaceae yozG ko:K07727 ko00000,ko03000 Bacteria 1VESP@1239,3F802@33958,4HPRB@91061,COG3655@1,COG3655@2 NA|NA|NA K Transcriptional regulator GHBLAFEN_00781 326425.lhe_0366 2.1e-32 144.4 Lactobacillaceae Bacteria 1U6VJ@1239,2AS5U@1,31HIR@2,3F8JX@33958,4IGPG@91061 NA|NA|NA GHBLAFEN_00782 326425.lhe_0367 5.6e-26 122.9 Lactobacillaceae Bacteria 1U6SR@1239,2B46M@1,31WXN@2,3F8F7@33958,4IGKA@91061 NA|NA|NA GHBLAFEN_00783 1423748.BALB01000012_gene1216 0.0 1548.5 Lactobacillaceae malZ 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 GH31 Bacteria 1TR8N@1239,3F4CE@33958,4HB1D@91061,COG1501@1,COG1501@2 NA|NA|NA G Belongs to the glycosyl hydrolase 31 family GHBLAFEN_00786 405566.lhv_1846 1.8e-136 491.9 Lactobacillaceae fruR ko:K03436 ko00000,ko03000 Bacteria 1TSF8@1239,3F3JB@33958,4HDT9@91061,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain GHBLAFEN_00787 405566.lhv_1845 1.1e-167 595.9 Lactobacillaceae pfkB 2.7.1.11,2.7.1.56 ko:K00882,ko:K16370 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00345 R00756,R02071,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ36@1239,3F3SG@33958,4HANU@91061,COG1105@1,COG1105@2 NA|NA|NA H Belongs to the carbohydrate kinase PfkB family. LacC subfamily GHBLAFEN_00791 405566.lhv_1140 3e-290 1003.8 Lactobacillaceae ko:K06148 ko00000,ko02000 3.A.1 Bacteria 1UYYQ@1239,3F5DU@33958,4HWP7@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region GHBLAFEN_00792 326425.lhe_0804 9.5e-38 162.5 Lactobacillaceae Bacteria 1U6TT@1239,3F8H4@33958,4IGMM@91061,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase GHBLAFEN_00793 405566.lhv_1141 5.1e-290 1003.0 Lactobacillaceae ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1V08F@1239,3F517@33958,4HTAU@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region GHBLAFEN_00794 326425.lhe_0806 1.4e-37 161.8 Lactobacillaceae Bacteria 1U6G3@1239,29PDV@1,30AC1@2,3F7U6@33958,4IG84@91061 NA|NA|NA GHBLAFEN_00795 1423748.BALB01000024_gene1742 4e-43 181.0 Lactobacillaceae Bacteria 1U6X8@1239,2B4TT@1,31XKC@2,3F8NJ@33958,4IGRH@91061 NA|NA|NA GHBLAFEN_00796 405566.lhv_1143 1.3e-134 485.7 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1UHYH@1239,3FC3I@33958,4ISGA@91061,COG4555@1,COG4555@2 NA|NA|NA CP ATPases associated with a variety of cellular activities GHBLAFEN_00797 405566.lhv_1144 4.5e-124 450.7 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V6XJ@1239,3F58X@33958,4HITU@91061,COG0842@1,COG0842@2 NA|NA|NA V Transport permease protein GHBLAFEN_00798 405566.lhv_1145 1.6e-105 389.0 Bacilli ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1UK2J@1239,4ITGC@91061,COG0842@1,COG0842@2 NA|NA|NA V Transport permease protein GHBLAFEN_00799 405566.lhv_2508 1.7e-78 298.5 Lactobacillaceae Bacteria 1UTR4@1239,3F5D1@33958,4HG6W@91061,COG3385@1,COG3385@2 NA|NA|NA L COG3385 FOG Transposase and inactivated derivatives GHBLAFEN_00800 326425.lhe_1043 1.4e-138 498.8 Lactobacillaceae treC GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005991,GO:0005993,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008788,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0015927,GO:0016052,GO:0016787,GO:0016798,GO:0033554,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046352,GO:0050896,GO:0051716,GO:0071704,GO:1901575 3.2.1.93 ko:K01226 ko00500,map00500 R00837,R06113 RC00049 ko00000,ko00001,ko01000 GH13 iECW_1372.ECW_m4600,iEKO11_1354.EKO11_4072,iEcE24377_1341.EcE24377A_4811,iEcSMS35_1347.EcSMS35_4720,iWFL_1372.ECW_m4600 Bacteria 1TP53@1239,3F41I@33958,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain protein GHBLAFEN_00801 1033837.WANG_0315 1.9e-305 1054.3 Lactobacillaceae Bacteria 1W1FZ@1239,2FIUN@1,34AK2@2,3F4QI@33958,4HYXZ@91061 NA|NA|NA GHBLAFEN_00802 1033837.WANG_0316 4.7e-81 307.0 Lactobacillaceae Bacteria 1W4GP@1239,28WWC@1,2ZIVN@2,3F5SC@33958,4I0DB@91061 NA|NA|NA GHBLAFEN_00803 326425.lhe_1046 2.4e-109 401.4 Lactobacillaceae msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 ko00000,ko01000 Bacteria 1TQ3E@1239,3F3YI@33958,4HAIV@91061,COG0225@1,COG0225@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine GHBLAFEN_00804 326425.lhe_1047 1.2e-64 252.3 Lactobacillaceae Bacteria 1W0V5@1239,2DYG7@1,349JS@2,3FC0P@33958,4HYMX@91061 NA|NA|NA S ASCH domain GHBLAFEN_00805 1423748.BALB01000020_gene1627 1.5e-54 218.8 Bacteria 4.4.1.5 ko:K01759 ko00620,map00620 R02530 RC00004,RC00740 ko00000,ko00001,ko01000 Bacteria COG0346@1,COG0346@2 NA|NA|NA E lactoylglutathione lyase activity GHBLAFEN_00806 405566.lhv_1161 5.5e-247 859.8 Lactobacillaceae 3.5.1.47 ko:K01436,ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TQ7B@1239,3F5DP@33958,4HE6F@91061,COG1473@1,COG1473@2 NA|NA|NA S Peptidase dimerisation domain GHBLAFEN_00807 353496.LBU_0897 1e-140 506.1 Lactobacillaceae Bacteria 1TSE4@1239,2Z7NA@2,3F5Z4@33958,4HE46@91061,arCOG09719@1 NA|NA|NA S Protein of unknown function (DUF3100) GHBLAFEN_00808 405566.lhv_2510 2.2e-82 311.6 Lactobacillaceae Bacteria 1V4WF@1239,2B1UF@1,31UAF@2,3F5V0@33958,4HI2Y@91061 NA|NA|NA S An automated process has identified a potential problem with this gene model GHBLAFEN_00809 1423748.BALB01000020_gene1624 2.1e-31 141.4 Lactobacillaceae Bacteria 1U48G@1239,29X5X@1,30IV1@2,3F84J@33958,4I46R@91061 NA|NA|NA GHBLAFEN_00810 585524.HMPREF0493_0561 1.4e-80 305.4 Lactobacillaceae XK26_02160 Bacteria 1U621@1239,3F6UR@33958,4IFR1@91061,COG5015@1,COG5015@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase GHBLAFEN_00811 585524.HMPREF0493_0562 4.7e-171 607.1 Lactobacillaceae yobV1 Bacteria 1TPS2@1239,3F56I@33958,4HDVX@91061,COG2378@1,COG2378@2 NA|NA|NA K WYL domain GHBLAFEN_00812 585524.HMPREF0493_0563 5.3e-68 263.5 Lactobacillaceae GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K07006 ko00000 Bacteria 1VGE7@1239,3F6YB@33958,4HNE7@91061,COG3576@1,COG3576@2 NA|NA|NA S pyridoxamine 5-phosphate GHBLAFEN_00813 585524.HMPREF0493_0564 1.3e-262 911.8 Lactobacillaceae npr 1.11.1.1 ko:K05910 ko00000,ko01000 Bacteria 1TPWW@1239,3F449@33958,4H9U7@91061,COG0446@1,COG0446@2 NA|NA|NA C NADH oxidase GHBLAFEN_00814 257314.LJ_1120 1.7e-20 104.8 Lactobacillaceae 1.1.1.1,1.1.1.14 ko:K00001,ko:K00008 ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 M00014 R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPIW@1239,3F42F@33958,4HB2G@91061,COG1063@1,COG1063@2 NA|NA|NA E alcohol dehydrogenase GHBLAFEN_00815 1033837.WANG_0628 1.7e-49 201.8 Lactobacillaceae mepA ko:K18908 M00705 ko00000,ko00002,ko01504,ko02000 2.A.66.1.13 Bacteria 1TPFM@1239,3F3KX@33958,4HEHY@91061,COG0534@1,COG0534@2 NA|NA|NA V MATE efflux family protein GHBLAFEN_00816 1033837.WANG_0627 0.0 1157.9 Lactobacillaceae cadA 3.6.3.3,3.6.3.5 ko:K01534 ko00000,ko01000 3.A.3.6 Bacteria 1TQ07@1239,3FC0Y@33958,4HT7C@91061,COG2217@1,COG2217@2 NA|NA|NA P E1-E2 ATPase GHBLAFEN_00817 1423748.BALB01000020_gene1610 6e-35 152.9 Lactobacillaceae copZ ko:K07213 ko04978,map04978 ko00000,ko00001 Bacteria 1VK5F@1239,3FBN8@33958,4IRA3@91061,COG2608@1,COG2608@2 NA|NA|NA C Heavy-metal-associated domain GHBLAFEN_00818 1423748.BALB01000020_gene1609 1e-88 332.8 Lactobacillaceae dps ko:K04047 ko00000,ko03036 Bacteria 1VB1X@1239,3F4SN@33958,4HMJG@91061,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family GHBLAFEN_00819 1423748.BALB01000020_gene1608 2e-109 401.7 Lactobacillaceae rcfA 4.1.99.16,4.2.3.22,4.2.3.75 ko:K10187,ko:K21562 ko00909,ko01100,ko01110,map00909,map01100,map01110 R07647,R07648,R08543,R09487 RC01832,RC02159,RC02160,RC02183,RC02425,RC02552 ko00000,ko00001,ko01000,ko03000 Bacteria 1V3XW@1239,3F4YM@33958,4HDG1@91061,COG0664@1,COG0664@2 NA|NA|NA K Transcriptional regulator, Crp Fnr family GHBLAFEN_00820 257314.LJ_1147 1.4e-59 236.5 Lactobacillaceae cbh 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 1TPZS@1239,3F4NH@33958,4HC4Y@91061,COG3049@1,COG3049@2 NA|NA|NA M Linear amide C-N hydrolase, choloylglycine hydrolase family protein GHBLAFEN_00821 326425.lhe_1061 2.2e-27 127.5 Lactobacillaceae Bacteria 1U5CK@1239,2ACE2@1,311ZJ@2,3F5IZ@33958,4IF3R@91061 NA|NA|NA GHBLAFEN_00822 1423748.BALB01000023_gene1712 0.0 1356.7 Lactobacillaceae Bacteria 1TPAT@1239,3F51D@33958,4HBR3@91061,COG1479@1,COG1479@2 NA|NA|NA S Protein of unknown function DUF262 GHBLAFEN_00823 1423748.BALB01000023_gene1711 1.3e-17 94.7 Lactobacillaceae Bacteria 1UJIG@1239,3F5WY@33958,4ITGD@91061,COG4889@1,COG4889@2 NA|NA|NA L helicase GHBLAFEN_00824 1423748.BALB01000029_gene1871 1.2e-35 155.2 Lactobacillaceae rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963,ko:K03111,ko:K15125 ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133 M00178 br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400 Bacteria 1V9XS@1239,3F7CY@33958,4HKCC@91061,COG0238@1,COG0238@2 NA|NA|NA J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit GHBLAFEN_00825 326425.lhe_0008 9e-79 299.7 Lactobacillaceae ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 1V3WT@1239,3F66N@33958,4HH8I@91061,COG0629@1,COG0629@2 NA|NA|NA L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism GHBLAFEN_00826 405566.lhv_0007 4.2e-49 200.3 Lactobacillaceae rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 ko:K02990 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VA18@1239,3FCDH@33958,4HP6B@91061,COG0360@1,COG0360@2 NA|NA|NA J Binds together with S18 to 16S ribosomal RNA GHBLAFEN_00827 405566.lhv_0006 0.0 1575.8 Lactobacillaceae gyrA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TP2Z@1239,3F3YM@33958,4HAHY@91061,COG0188@1,COG0188@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner GHBLAFEN_00828 405566.lhv_0005 0.0 1293.9 Lactobacillaceae gyrB GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02470,ko:K02622 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TQ0R@1239,3F48M@33958,4H9Y6@91061,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner GHBLAFEN_00829 1423748.BALB01000029_gene1863 2.6e-208 731.1 Lactobacillaceae recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1TP9U@1239,3F3Q1@33958,4HA0W@91061,COG1195@1,COG1195@2 NA|NA|NA L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP GHBLAFEN_00830 405566.lhv_0003 1.7e-34 151.4 Lactobacillaceae yaaA GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K14761 ko00000,ko03009 Bacteria 1VEJ2@1239,3F803@33958,4HNMC@91061,COG2501@1,COG2501@2 NA|NA|NA S S4 domain protein YaaA GHBLAFEN_00831 405566.lhv_0002 3.9e-196 690.6 Lactobacillaceae dnaN 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TQ7J@1239,3F3ZQ@33958,4H9TF@91061,COG0592@1,COG0592@2 NA|NA|NA L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria GHBLAFEN_00832 326425.lhe_0001 4.1e-256 890.2 Lactobacillaceae dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 1TPV7@1239,3F3YA@33958,4H9MW@91061,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids GHBLAFEN_00833 1033837.WANG_1471 1.1e-15 88.2 Lactobacillaceae rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02914 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VK90@1239,3F81W@33958,4HR2Z@91061,COG0230@1,COG0230@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL34 family GHBLAFEN_00834 326425.lhe_1927 2.7e-61 241.1 Lactobacillaceae rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536,ko:K08998 ko00000,ko01000,ko03016 Bacteria 1VA78@1239,3F6GS@33958,4HKG6@91061,COG0594@1,COG0594@2 NA|NA|NA J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme GHBLAFEN_00835 405566.lhv_2105 1e-143 516.2 Lactobacillaceae yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 1TQ0J@1239,3F3SD@33958,4HB3J@91061,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins GHBLAFEN_00836 405566.lhv_2104 6.2e-252 876.3 Lactobacillaceae mnmE GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K03650 R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 Bacteria 1TPJF@1239,3F3WA@33958,4HA06@91061,COG0486@1,COG0486@2 NA|NA|NA S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 GHBLAFEN_00837 326425.lhe_1924 0.0 1237.6 Lactobacillaceae gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 ko:K03495 R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 Bacteria 1TQ4B@1239,3F454@33958,4HA6S@91061,COG0445@1,COG0445@2 NA|NA|NA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 GHBLAFEN_00838 326425.lhe_1923 1.1e-269 935.3 Lactobacillaceae gnd 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4I@1239,3F3S8@33958,4H9NC@91061,COG0362@1,COG0362@2 NA|NA|NA H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH GHBLAFEN_00839 326425.lhe_1922 7.9e-280 969.1 Lactobacillaceae clcA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006821,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015672,GO:0015698,GO:0015706,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0031404,GO:0034220,GO:0042802,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 ko:K03281,ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4,2.A.49 iAF1260.b0155,iB21_1397.B21_00153,iBWG_1329.BWG_0148,iE2348C_1286.E2348C_0162,iEC042_1314.EC042_0155,iEC55989_1330.EC55989_0149,iECBD_1354.ECBD_3463,iECDH10B_1368.ECDH10B_0135,iECDH1ME8569_1439.ECDH1ME8569_0149,iECD_1391.ECD_00154,iECIAI1_1343.ECIAI1_0153,iECO103_1326.ECO103_0155,iECSE_1348.ECSE_0156,iECUMN_1333.ECUMN_0152,iECW_1372.ECW_m0152,iEKO11_1354.EKO11_3761,iETEC_1333.ETEC_0151,iEcDH1_1363.EcDH1_3447,iEcE24377_1341.EcE24377A_0160,iEcolC_1368.EcolC_3504,iJO1366.b0155,iSSON_1240.SSON_0167,iUMNK88_1353.UMNK88_159,iWFL_1372.ECW_m0152,iY75_1357.Y75_RS00790,iZ_1308.Z0166 Bacteria 1TPX0@1239,3F3MU@33958,4HD2H@91061,COG0038@1,COG0038@2,COG0569@1,COG0569@2 NA|NA|NA P chloride GHBLAFEN_00840 326425.lhe_1921 7.2e-211 739.6 Lactobacillaceae Bacteria 1U547@1239,29NJT@1,309HR@2,3F4IW@33958,4IEVJ@91061 NA|NA|NA GHBLAFEN_00841 1033837.WANG_1480 1.2e-18 98.2 Lactobacillaceae Bacteria 1U6JH@1239,29PGF@1,30AEK@2,3F819@33958,4IGBZ@91061 NA|NA|NA GHBLAFEN_00842 1423748.BALB01000021_gene1650 8.5e-81 306.6 Lactobacillaceae ko:K08368 ko00000,ko02000 2.A.1 Bacteria 1UHPS@1239,3FBSX@33958,4HD28@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter GHBLAFEN_00843 1423748.BALB01000021_gene1650 2.2e-38 164.5 Lactobacillaceae ko:K08368 ko00000,ko02000 2.A.1 Bacteria 1UHPS@1239,3FBSX@33958,4HD28@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter GHBLAFEN_00844 1423748.BALB01000021_gene1650 5.6e-17 92.8 Lactobacillaceae ko:K08368 ko00000,ko02000 2.A.1 Bacteria 1UHPS@1239,3FBSX@33958,4HD28@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter GHBLAFEN_00845 405566.lhv_2097 0.0 1179.1 Lactobacillaceae copA 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 1TP5S@1239,3F4IX@33958,4HAI0@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase GHBLAFEN_00846 326425.lhe_1917 1.4e-49 201.8 Lactobacillaceae silP 1.9.3.1,3.6.3.54 ko:K02275,ko:K17686 ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016 M00155 R00081,R00086 RC00002,RC00016 ko00000,ko00001,ko00002,ko01000 3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 1U632@1239,3F6XB@33958,4IFSB@91061,COG4633@1,COG4633@2 NA|NA|NA S Cupredoxin-like domain GHBLAFEN_00847 326425.lhe_1916 1.2e-64 252.3 Lactobacillaceae silP 1.9.3.1,3.6.3.54 ko:K02275,ko:K17686 ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016 M00155 R00081,R00086 RC00002,RC00016 ko00000,ko00001,ko00002,ko01000 3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 1TQ02@1239,3FBQA@33958,4IRVT@91061,COG4633@1,COG4633@2 NA|NA|NA S Cupredoxin-like domain GHBLAFEN_00848 326425.lhe_1915 2.7e-76 291.2 Lactobacillaceae atkY Bacteria 1V7EY@1239,3FBNQ@33958,4HP8S@91061,COG3682@1,COG3682@2 NA|NA|NA K Penicillinase repressor GHBLAFEN_00849 326425.lhe_1914 2.3e-35 154.5 Lactobacillaceae Bacteria 1U6NN@1239,29PJ2@1,30AH7@2,3F87H@33958,4IGFM@91061 NA|NA|NA GHBLAFEN_00850 1423748.BALB01000021_gene1657 6.7e-224 783.1 Lactobacillaceae pbuG ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 1TQC6@1239,3F44D@33958,4HANG@91061,COG2252@1,COG2252@2 NA|NA|NA S permease GHBLAFEN_00851 405566.lhv_1092 1.3e-63 248.8 Lactobacillaceae Bacteria 1UZVA@1239,3F4KP@33958,4HH09@91061,COG3039@1,COG3039@2 NA|NA|NA L An automated process has identified a potential problem with this gene model GHBLAFEN_00852 405566.lhv_1093 0.0 1397.5 Lactobacillaceae yaaO 4.1.1.17,4.1.1.19 ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00133,M00134 R00566,R00670 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 1TNZ9@1239,3F3TV@33958,4HBGC@91061,COG1982@1,COG1982@2 NA|NA|NA E Orn/Lys/Arg decarboxylase, C-terminal domain GHBLAFEN_00853 326425.lhe_0997 2.5e-247 860.9 Lactobacillaceae ynbB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 4.4.1.1 ko:K01758 ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230 M00338 R00782,R01001,R02408,R04770,R04930,R09366 RC00056,RC00069,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TQ88@1239,3F3PU@33958,4HAF5@91061,COG4100@1,COG4100@2 NA|NA|NA P aluminum resistance GHBLAFEN_00854 1423748.BALB01000009_gene1036 2.9e-88 331.3 Lactobacillaceae ktrA ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1TQ9H@1239,3F5G0@33958,4HBPH@91061,COG0569@1,COG0569@2 NA|NA|NA P domain protein GHBLAFEN_00855 1423748.BALB01000009_gene1037 2.7e-178 631.3 Lactobacillaceae ktrB ko:K03498 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1TQ4S@1239,3F5BE@33958,4H9ME@91061,COG0168@1,COG0168@2 NA|NA|NA P Potassium uptake protein GHBLAFEN_00856 326425.lhe_0998 0.0 1176.8 Lactobacillaceae recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPN5@1239,3F4PY@33958,4H9QP@91061,COG0514@1,COG0514@2 NA|NA|NA L ATP-dependent DNA helicase RecQ GHBLAFEN_00857 326425.lhe_0999 1.7e-78 298.5 Lactobacillaceae Bacteria 1V465@1239,3F7H7@33958,4HN5X@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin GHBLAFEN_00858 326425.lhe_1000 1.3e-111 409.1 Lactobacillaceae 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1V7XD@1239,3FBEV@33958,4IPZ9@91061,COG0671@1,COG0671@2 NA|NA|NA I Acid phosphatase homologues GHBLAFEN_00859 326425.lhe_1001 2.7e-106 391.3 Lactobacillaceae lacA 2.3.1.79 ko:K00661 ko00000,ko01000 Bacteria 1V06U@1239,3FBEW@33958,4IPZB@91061,COG0110@1,COG0110@2 NA|NA|NA S Transferase hexapeptide repeat GHBLAFEN_00860 405566.lhv_1103 2.2e-207 728.0 Lactobacillaceae pbpX1 Bacteria 1U52D@1239,3F440@33958,4IETU@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase GHBLAFEN_00861 326425.lhe_1003 1.2e-149 535.8 Lactobacillaceae pdxK 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TRCR@1239,3F3V7@33958,4HHME@91061,COG2240@1,COG2240@2 NA|NA|NA H Phosphomethylpyrimidine kinase GHBLAFEN_00862 326425.lhe_1004 5.8e-92 343.6 Lactobacillaceae ko:K16923 M00582 ko00000,ko00002,ko02000 3.A.1.28 Bacteria 1V52B@1239,3F4W9@33958,4HKM2@91061,COG4720@1,COG4720@2 NA|NA|NA S ECF-type riboflavin transporter, S component GHBLAFEN_00863 405566.lhv_1106 8.1e-232 809.3 Lactobacillaceae Bacteria 1TQMA@1239,3F3QW@33958,4HDTN@91061,COG1376@1,COG1376@2 NA|NA|NA S Putative peptidoglycan binding domain GHBLAFEN_00864 405566.lhv_1107 1.2e-236 825.5 Lactobacillaceae mepA ko:K18908 M00705 ko00000,ko00002,ko01504,ko02000 2.A.66.1.13 Bacteria 1TPFM@1239,3F3KX@33958,4HEHY@91061,COG0534@1,COG0534@2 NA|NA|NA V MATE efflux family protein GHBLAFEN_00865 326425.lhe_1007 8.6e-256 889.0 Lactobacillaceae pepT2 3.4.11.14,3.4.11.4 ko:K01258,ko:K01263 ko00000,ko01000,ko01002 Bacteria 1TP3A@1239,3F45V@33958,4HAZE@91061,COG2195@1,COG2195@2 NA|NA|NA E Cleaves the N-terminal amino acid of tripeptides GHBLAFEN_00866 326425.lhe_1008 1.9e-33 147.9 Lactobacillaceae Bacteria 1U6P4@1239,2AR8Z@1,31GIU@2,3F88G@33958,4IGG4@91061 NA|NA|NA GHBLAFEN_00867 1423748.BALB01000009_gene1051 1.4e-29 135.2 Lactobacillaceae fic ko:K04095 ko00000,ko03036 Bacteria 1VK13@1239,3F711@33958,4IQYB@91061,COG2184@1,COG2184@2 NA|NA|NA D Fic/DOC family GHBLAFEN_00868 1423748.BALB01000009_gene1052 2.2e-60 238.0 Lactobacillaceae Bacteria 1U5Z5@1239,29P12@1,309Z7@2,3F6QZ@33958,4IFN5@91061 NA|NA|NA GHBLAFEN_00869 405566.lhv_1111 1.2e-250 872.1 Lactobacillaceae Bacteria 1TSRV@1239,3F514@33958,4HCIZ@91061,COG1132@1,COG1132@2 NA|NA|NA P ABC transporter GHBLAFEN_00870 405566.lhv_1112 1.7e-293 1014.6 Lactobacillaceae Bacteria 1TSRV@1239,3F46B@33958,4HCIZ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC-type multidrug transport system, ATPase and permease components GHBLAFEN_00871 405566.lhv_1113 9.2e-69 266.9 Lactobacillaceae Bacteria 1VKFR@1239,3F4TV@33958,4HRQ4@91061,COG3595@1,COG3595@2 NA|NA|NA S Putative adhesin GHBLAFEN_00872 405566.lhv_1114 1.3e-58 232.3 Lactobacillaceae ypaA ko:K08987 ko00000 Bacteria 1VAVU@1239,3F7NA@33958,4HQHN@91061,COG3759@1,COG3759@2 NA|NA|NA S Protein of unknown function (DUF1304) GHBLAFEN_00874 326425.lhe_1011 3.3e-78 297.7 Lactobacillaceae Bacteria 1U6XC@1239,2C5CP@1,30ANW@2,3F8NS@33958,4IGRM@91061 NA|NA|NA GHBLAFEN_00875 326425.lhe_1012 2.4e-56 224.9 Lactobacillaceae Bacteria 1U5S0@1239,29NX2@1,309V6@2,3F6ET@33958,4IFGA@91061 NA|NA|NA GHBLAFEN_00876 405566.lhv_1117 3.2e-115 421.0 Lactobacillaceae Bacteria 1V3AX@1239,3F4YX@33958,4HVK3@91061,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family GHBLAFEN_00877 326425.lhe_1014 1.7e-102 378.6 Lactobacillaceae Bacteria 1U5RF@1239,2A1GN@1,30PQ9@2,3F6DA@33958,4IFFK@91061 NA|NA|NA GHBLAFEN_00878 405566.lhv_1119 3e-207 727.6 Lactobacillaceae ko:K08152 ko00000,ko02000 2.A.1.2 Bacteria 1W01A@1239,3F4S8@33958,4HZ1U@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GHBLAFEN_00879 405566.lhv_1120 2.3e-133 481.5 Lactobacillaceae Bacteria 1VDYG@1239,2C6BP@1,32SQP@2,3F5TH@33958,4HS7C@91061 NA|NA|NA GHBLAFEN_00880 1033837.WANG_1181 1.2e-25 122.5 Lactobacillaceae 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1A7@1239,3F655@33958,4HG0B@91061,COG5464@1,COG5464@2 NA|NA|NA S PD-(D/E)XK nuclease family transposase GHBLAFEN_00881 1423748.BALB01000005_gene656 1.7e-29 135.2 Lactobacillaceae frnE Bacteria 1TZ1N@1239,3F5IF@33958,4HEBF@91061,COG2761@1,COG2761@2 NA|NA|NA Q DSBA-like thioredoxin domain GHBLAFEN_00882 1423748.BALB01000005_gene656 2.3e-37 161.0 Lactobacillaceae frnE Bacteria 1TZ1N@1239,3F5IF@33958,4HEBF@91061,COG2761@1,COG2761@2 NA|NA|NA Q DSBA-like thioredoxin domain GHBLAFEN_00883 326425.lhe_1578 7.7e-174 616.3 Lactobacillaceae trxB 1.8.1.9 ko:K00384 ko00450,map00450 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 Bacteria 1TNZS@1239,3F411@33958,4HA4N@91061,COG0492@1,COG0492@2 NA|NA|NA C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family GHBLAFEN_00884 405566.lhv_1714 2.3e-116 424.9 Lactobacillaceae M1-798 ko:K03892 ko00000,ko03000 Bacteria 1V2NW@1239,3F6DW@33958,4HGAA@91061,COG0607@1,COG0607@2,COG0640@1,COG0640@2 NA|NA|NA K Rhodanese Homology Domain GHBLAFEN_00885 405566.lhv_1715 2e-58 231.5 Lactobacillaceae ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1U6PP@1239,3F89E@33958,4IGGN@91061,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin GHBLAFEN_00886 326425.lhe_1581 2.1e-20 104.0 Lactobacillaceae Bacteria 1U892@1239,29QKD@1,30BK1@2,3FAQ3@33958,4II6X@91061 NA|NA|NA GHBLAFEN_00887 1423748.BALB01000005_gene651 3.3e-12 78.2 Lactobacillaceae Bacteria 1VSP5@1239,3F4FY@33958,4HUK1@91061,COG3266@1,COG3266@2 NA|NA|NA UW LPXTG-motif cell wall anchor domain protein GHBLAFEN_00888 324831.LGAS_0045 2.3e-49 202.6 Lactobacillaceae infB ko:K02519,ko:K03832 ko00000,ko02000,ko03012,ko03029 2.C.1.1 Bacteria 1VSP5@1239,3F4FY@33958,4HUK1@91061,COG0810@1,COG0810@2,COG3266@1,COG3266@2,COG4932@1,COG4932@2 NA|NA|NA UW LPXTG-motif cell wall anchor domain protein GHBLAFEN_00889 1423748.BALB01000005_gene644 3.2e-64 251.1 Lactobacillaceae Bacteria 1TPH1@1239,3F3M5@33958,4HBQH@91061,COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family GHBLAFEN_00890 1423748.BALB01000005_gene644 6.7e-93 347.4 Lactobacillaceae Bacteria 1TPH1@1239,3F3M5@33958,4HBQH@91061,COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family GHBLAFEN_00891 326425.lhe_1057 2.6e-227 795.4 Lactobacillaceae Bacteria 1TPH1@1239,3F3M5@33958,4HBQH@91061,COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family GHBLAFEN_00892 326425.lhe_0391 6.7e-49 199.9 Lactobacillaceae Bacteria 1U644@1239,2BZTJ@1,30A2T@2,3F6ZQ@33958,4IFTP@91061 NA|NA|NA GHBLAFEN_00893 1033837.WANG_0175 1.3e-55 222.2 Lactobacillaceae dhaM GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324 2.7.1.121 ko:K05881 ko00561,map00561 R01012 RC00015,RC00017 ko00000,ko00001,ko01000,ko02000 Bacteria 1VF32@1239,3F6YE@33958,4HKCN@91061,COG3412@1,COG3412@2 NA|NA|NA S PTS system fructose IIA component GHBLAFEN_00894 272621.LBA1434 3e-91 341.3 Lactobacillaceae dhaL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0046872,GO:0047324,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.1.121 ko:K05879 ko00561,ko01100,map00561,map01100 R01012 RC00015,RC00017 ko00000,ko00001,ko01000 Bacteria 1V4FH@1239,3F5VS@33958,4HGZY@91061,COG1461@1,COG1461@2 NA|NA|NA S Dak2 GHBLAFEN_00895 1033837.WANG_0173 2.2e-182 644.8 Lactobacillaceae dhaK GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019637,GO:0019751,GO:0033554,GO:0034308,GO:0042180,GO:0042182,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0047324,GO:0050896,GO:0051716,GO:0061610,GO:0071704,GO:1901135,GO:1901575,GO:1901615 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 ko:K00863,ko:K05878,ko:K05879 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 M00344 R01011,R01012,R01059 RC00002,RC00015,RC00017 ko00000,ko00001,ko00002,ko01000 iEcHS_1320.EcHS_A1304,iUMNK88_1353.UMNK88_1515,iYL1228.KPN_03495 Bacteria 1TP92@1239,3F4F2@33958,4H9VS@91061,COG2376@1,COG2376@2 NA|NA|NA G Dak1 domain GHBLAFEN_00896 405566.lhv_1725 3.7e-296 1023.5 Lactobacillaceae ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03328,ko:K06409 ko00000,ko02000 2.A.66.2,2.A.66.2.14 Bacteria 1TNYX@1239,3F404@33958,4H9RY@91061,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein GHBLAFEN_00897 405566.lhv_1726 0.0 1684.8 Lactobacillaceae leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TP0Y@1239,3F46M@33958,4HAG1@91061,COG0495@1,COG0495@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family GHBLAFEN_00898 405566.lhv_1727 1.3e-119 435.6 Lactobacillaceae 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1VF2U@1239,3F5CM@33958,4HNXR@91061,COG0671@1,COG0671@2 NA|NA|NA I Acid phosphatase homologues GHBLAFEN_00899 1423748.BALB01000034_gene1968 1.1e-149 536.2 Lactobacillaceae hepT 2.5.1.30,2.5.1.90 ko:K00805,ko:K02523 ko00900,ko01110,map00900,map01110 R09247,R09248 RC00279 ko00000,ko00001,ko01000,ko01006 Bacteria 1TR0U@1239,3F4GC@33958,4H9RH@91061,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family GHBLAFEN_00900 326425.lhe_1591 7e-262 909.4 Lactobacillaceae qacA Bacteria 1VSW8@1239,3F4AW@33958,4HUQC@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GHBLAFEN_00901 1423748.BALB01000034_gene1966 2.5e-217 761.1 Lactobacillaceae metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCV@1239,3F3T0@33958,4HB33@91061,COG0192@1,COG0192@2 NA|NA|NA H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme GHBLAFEN_00904 405566.lhv_1732 3.6e-168 597.4 Lactobacillaceae psaA ko:K02077 M00244 ko00000,ko00002,ko02000 3.A.1.15 Bacteria 1V110@1239,3FC74@33958,4HE71@91061,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family GHBLAFEN_00906 326425.lhe_1801 8e-28 129.4 Lactobacillaceae Bacteria 1V7W5@1239,2APNN@1,31ES7@2,3F70U@33958,4HJDN@91061 NA|NA|NA GHBLAFEN_00908 326425.lhe_1803 1.4e-297 1028.1 Lactobacillaceae lysS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP2P@1239,3F439@33958,4H9X4@91061,COG1190@1,COG1190@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family GHBLAFEN_00909 405566.lhv_0298 1.1e-194 685.6 Lactobacillaceae dus ko:K05540 ko00000,ko01000,ko03016 Bacteria 1TQ2R@1239,3F4C6@33958,4HA9K@91061,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines GHBLAFEN_00910 326425.lhe_1805 1.5e-161 575.5 Lactobacillaceae hslO GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008 ko:K04083 ko00000,ko03110 Bacteria 1TRCH@1239,3F42B@33958,4HAFR@91061,COG1281@1,COG1281@2 NA|NA|NA O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress GHBLAFEN_00911 405566.lhv_0296 0.0 1262.7 Lactobacillaceae ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 ko:K03798 M00742 ko00000,ko00002,ko01000,ko01002,ko03110 Bacteria 1TPTV@1239,3F49Z@33958,4HAJB@91061,COG0465@1,COG0465@2 NA|NA|NA O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins GHBLAFEN_00912 405566.lhv_0295 1.2e-241 842.0 Lactobacillaceae tilS 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 1TPXP@1239,3F4GY@33958,4H9ZM@91061,COG0037@1,COG0037@2 NA|NA|NA J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine GHBLAFEN_00913 326425.lhe_1808 2.2e-60 238.0 Lactobacillaceae yabR ko:K07570,ko:K07571 ko00000 Bacteria 1UI95@1239,3F6P8@33958,4ISGM@91061,COG1098@1,COG1098@2 NA|NA|NA J S1 RNA binding domain GHBLAFEN_00914 405566.lhv_0293 5.8e-59 233.4 Lactobacillaceae divIC ko:K05589,ko:K13052 ko00000,ko03036 Bacteria 1VKC5@1239,3F76Z@33958,4HR53@91061,COG2919@1,COG2919@2 NA|NA|NA D Septum formation initiator GHBLAFEN_00915 326425.lhe_1810 1.8e-34 151.4 Lactobacillaceae yabO GO:0008150,GO:0040007 Bacteria 1VEI5@1239,3F7JX@33958,4HKJJ@91061,COG1188@1,COG1188@2 NA|NA|NA J S4 domain protein GHBLAFEN_00916 405566.lhv_0291 0.0 2244.9 Lactobacillaceae mfd ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPF1@1239,3F4KU@33958,4H9NB@91061,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site GHBLAFEN_00917 405566.lhv_0290 4.3e-103 380.6 Lactobacillaceae pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 1V3NB@1239,3F3VZ@33958,4HH2Z@91061,COG0193@1,COG0193@2 NA|NA|NA J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis GHBLAFEN_00918 405566.lhv_0289 7.3e-183 646.4 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPSY@1239,3F3RM@33958,4HB0Z@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily. LDH family GHBLAFEN_00919 1423748.BALB01000002_gene350 2.4e-127 461.5 Lactobacillaceae Bacteria 1TR5G@1239,3F3JY@33958,4H9ZA@91061,COG0517@1,COG0517@2 NA|NA|NA S (CBS) domain GHBLAFEN_00920 1423748.BALB01000002_gene351 2.9e-92 344.7 Lactobacillaceae Bacteria 1U689@1239,3F7AB@33958,4IFZ0@91061,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator GHBLAFEN_00921 326425.lhe_1816 1e-215 755.7 Lactobacillaceae alr 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011 Bacteria 1TNYY@1239,3F3X2@33958,4HA95@91061,COG0787@1,COG0787@2 NA|NA|NA E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids GHBLAFEN_00922 326425.lhe_1817 1.7e-60 238.4 Lactobacillaceae acpS 2.7.6.3,2.7.8.7,5.1.1.1 ko:K00950,ko:K00997,ko:K01775 ko00473,ko00770,ko00790,ko01100,ko01502,map00473,map00770,map00790,map01100,map01502 M00126,M00841 R00401,R01625,R03503 RC00002,RC00017,RC00285 ko00000,ko00001,ko00002,ko01000,ko01011 iYO844.BSU04620 Bacteria 1VA0T@1239,3F6HC@33958,4HKBI@91061,COG0736@1,COG0736@2 NA|NA|NA I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein GHBLAFEN_00923 326425.lhe_1818 5.5e-246 856.7 Lactobacillaceae cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TPAP@1239,3F46Q@33958,4HAB3@91061,COG0513@1,COG0513@2 NA|NA|NA F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity GHBLAFEN_00924 326425.lhe_1819 1e-262 912.1 Lactobacillaceae murF 6.3.2.10,6.3.2.13 ko:K01928,ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R02788,R04573,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1VT78@1239,3F4SK@33958,4HACR@91061,COG0770@1,COG0770@2 NA|NA|NA M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein GHBLAFEN_00925 326425.lhe_1820 1.3e-38 165.2 Lactobacillaceae rpmE2 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEGU@1239,3FCDM@33958,4HNQF@91061,COG0254@1,COG0254@2 NA|NA|NA J Ribosomal protein L31 GHBLAFEN_00926 405566.lhv_0280 1.6e-157 562.0 Lactobacillaceae Bacteria 1TREF@1239,3F5C1@33958,4H9Y9@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase GHBLAFEN_00927 1423748.BALB01000003_gene414 1.5e-61 241.9 Lactobacillaceae yodB Bacteria 1VBI7@1239,3F7FK@33958,4HKBR@91061,COG1733@1,COG1733@2 NA|NA|NA K Transcriptional regulator, HxlR family GHBLAFEN_00928 405566.lhv_1581 2e-202 711.4 Lactobacillaceae pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPFW@1239,3F4NT@33958,4HAVN@91061,COG0016@1,COG0016@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily GHBLAFEN_00929 326425.lhe_1463 0.0 1595.1 Lactobacillaceae pheT GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_2160,iPC815.YPO2428 Bacteria 1TP98@1239,3F3V3@33958,4HAQ9@91061,COG0072@1,COG0072@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily GHBLAFEN_00930 1423748.BALB01000003_gene418 9.2e-62 243.0 Lactobacillaceae greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K03624 ko00000,ko03021 Bacteria 1V44S@1239,3F4ZF@33958,4HGZU@91061,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides GHBLAFEN_00931 405566.lhv_1578 1.6e-168 598.6 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1TQIV@1239,3FBIV@33958,4IQTH@91061,COG0039@1,COG0039@2 NA|NA|NA C lactate/malate dehydrogenase, alpha/beta C-terminal domain GHBLAFEN_00932 326425.lhe_1460 2.8e-26 124.0 Lactobacillaceae GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0045926,GO:0045927,GO:0046483,GO:0048518,GO:0048519,GO:0050789,GO:0050896,GO:0065007,GO:0070482,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 Bacteria 1VB8K@1239,3F7HF@33958,4HKT7@91061,COG4679@1,COG4679@2 NA|NA|NA S Phage derived protein Gp49-like (DUF891) GHBLAFEN_00933 326425.lhe_1459 9e-38 162.5 Lactobacillaceae Bacteria 1UJGN@1239,3FBV2@33958,4IT9F@91061,COG3620@1,COG3620@2 NA|NA|NA K Helix-turn-helix domain GHBLAFEN_00934 326425.lhe_1458 1.5e-169 602.1 Lactobacillaceae 2.7.1.59 ko:K00884 ko00520,ko01100,map00520,map01100 R01201 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1V38W@1239,3F5MG@33958,4HGPI@91061,COG2971@1,COG2971@2 NA|NA|NA G BadF/BadG/BcrA/BcrD ATPase family GHBLAFEN_00935 405566.lhv_1571 0.0 1640.9 Lactobacillaceae Bacteria 1TRR1@1239,3F49G@33958,4HBW6@91061,COG4485@1,COG4485@2 NA|NA|NA S membrane GHBLAFEN_00936 326425.lhe_1456 0.0 1365.5 Lactobacillaceae pbp2b 3.4.16.4 ko:K00687,ko:K05515,ko:K12553,ko:K21465 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Bacteria 1TQHY@1239,3F3KH@33958,4HAFX@91061,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein GHBLAFEN_00937 1423748.BALB01000003_gene424 1.2e-20 104.8 Lactobacillaceae rpmG ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEJ4@1239,3F828@33958,4HNIM@91061,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family GHBLAFEN_00938 326425.lhe_1454 1.7e-99 368.6 Lactobacillaceae ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 Bacteria 1VA91@1239,3FC8W@33958,4HKQI@91061,COG0212@1,COG0212@2 NA|NA|NA H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family GHBLAFEN_00939 405566.lhv_1567 3.2e-116 424.5 Lactobacillaceae gluP 3.4.21.105 ko:K19225 ko00000,ko01000,ko01002 Bacteria 1TQXT@1239,3FC8V@33958,4HCDF@91061,COG0705@1,COG0705@2 NA|NA|NA S Rhomboid family GHBLAFEN_00940 326425.lhe_1452 5.6e-33 146.4 Lactobacillaceae yqgQ Bacteria 1VK83@1239,3F83I@33958,4HRG2@91061,COG4483@1,COG4483@2 NA|NA|NA S Bacterial protein of unknown function (DUF910) GHBLAFEN_00941 405566.lhv_1565 4.5e-70 270.4 Lactobacillaceae yqhL Bacteria 1VAI7@1239,3F67E@33958,4HKCE@91061,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese-like protein GHBLAFEN_00942 326425.lhe_1450 3.6e-171 607.4 Lactobacillaceae miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 1TPSC@1239,3F3XS@33958,4HAVW@91061,COG0324@1,COG0324@2 NA|NA|NA F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) GHBLAFEN_00943 1423748.BALB01000003_gene430 2.6e-30 137.5 Lactobacillaceae ynbB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 4.4.1.1 ko:K01758 ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230 M00338 R00782,R01001,R02408,R04770,R04930,R09366 RC00056,RC00069,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TQ88@1239,3F3PU@33958,4HAF5@91061,COG4100@1,COG4100@2 NA|NA|NA P aluminum resistance GHBLAFEN_00944 1423748.BALB01000003_gene430 5.1e-170 603.6 Lactobacillaceae ynbB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 4.4.1.1 ko:K01758 ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230 M00338 R00782,R01001,R02408,R04770,R04930,R09366 RC00056,RC00069,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TQ88@1239,3F3PU@33958,4HAF5@91061,COG4100@1,COG4100@2 NA|NA|NA P aluminum resistance GHBLAFEN_00945 326425.lhe_1448 1.5e-263 914.8 Lactobacillaceae glnA 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 1TNZA@1239,3F41A@33958,4HACE@91061,COG0174@1,COG0174@2 NA|NA|NA E glutamine synthetase GHBLAFEN_00946 326425.lhe_1447 1.8e-135 488.8 Lactobacillaceae Bacteria 1U5CK@1239,2ACE2@1,311ZJ@2,3F5IZ@33958,4IF3R@91061 NA|NA|NA GHBLAFEN_00947 405566.lhv_1556 7.1e-164 583.2 Lactobacillaceae Bacteria 1U54Z@1239,2ACE2@1,309I3@2,3F4PW@33958,4IEW5@91061 NA|NA|NA GHBLAFEN_00948 326425.lhe_1445 2.3e-147 528.5 Lactobacillaceae Bacteria 1U5E7@1239,2ACE2@1,309NT@2,3F5PN@33958,4IF5H@91061 NA|NA|NA GHBLAFEN_00949 326425.lhe_0051 1.1e-232 812.4 Lactobacillaceae Bacteria 1U62D@1239,29P37@1,30A1D@2,3F6V7@33958,4IFRD@91061 NA|NA|NA S LPXTG cell wall anchor motif GHBLAFEN_00950 405566.lhv_0038 6.7e-147 526.6 Lactobacillaceae Bacteria 1V2HX@1239,3F3MV@33958,4HK25@91061,COG4905@1,COG4905@2 NA|NA|NA S Putative ABC-transporter type IV GHBLAFEN_00951 326425.lhe_0054 2.5e-98 364.8 Lactobacillaceae yvqK GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 ko:K00798,ko:K13821 ko00250,ko00330,ko00860,ko01100,ko01110,ko01130,map00250,map00330,map00860,map01100,map01110,map01130 M00122 R00245,R00707,R00708,R01253,R01492,R04444,R04445,R05051,R05220,R07268 RC00080,RC00083,RC00216,RC00242,RC00255,RC00533 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 1UZ2W@1239,3F6MY@33958,4HF48@91061,COG2096@1,COG2096@2 NA|NA|NA S cob(I)alamin adenosyltransferase GHBLAFEN_00952 326425.lhe_0055 1.7e-85 322.0 Lactobacillaceae ko:K16924,ko:K16927 M00582 ko00000,ko00002,ko02000 3.A.1.29,3.A.1.32 Bacteria 1V5GD@1239,3F5H7@33958,4HI8Y@91061,COG4720@1,COG4720@2 NA|NA|NA S ECF transporter, substrate-specific component GHBLAFEN_00953 326425.lhe_0056 2.1e-59 235.0 Lactobacillaceae Bacteria 1VF26@1239,2DNM7@1,32Y2X@2,3F6AM@33958,4HP82@91061 NA|NA|NA S Domain of unknown function (DUF4430) GHBLAFEN_00954 405566.lhv_0042 0.0 1525.4 Lactobacillaceae rtpR 1.1.98.6,1.17.4.1,1.17.4.2 ko:K00525,ko:K00527,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02014,R02017,R02018,R02019,R02020,R02022,R02023,R02024,R04315,R11633,R11634,R11635,R11636 RC00013,RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1TT3U@1239,3F3VU@33958,4HFF1@91061,COG0209@1,COG0209@2 NA|NA|NA F ribonucleoside-triphosphate reductase activity GHBLAFEN_00955 405566.lhv_0043 7.1e-176 623.2 Lactobacillaceae Bacteria 1TSBK@1239,3F46E@33958,4HBYJ@91061,COG0628@1,COG0628@2 NA|NA|NA K AI-2E family transporter GHBLAFEN_00956 326425.lhe_0059 2e-103 381.7 Lactobacillaceae 3.1.1.5 ko:K10804 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Bacteria 1VAT2@1239,3F5TI@33958,4HKYJ@91061,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase GHBLAFEN_00957 525365.HMPREF0548_1309 1.3e-11 75.1 Lactobacillaceae Bacteria 1U6MU@1239,2AR30@1,31GC3@2,3F85Z@33958,4IGEM@91061 NA|NA|NA GHBLAFEN_00958 1033837.WANG_1572 3.2e-51 207.6 Lactobacillaceae Bacteria 1U644@1239,2BZTJ@1,30A2T@2,3F6ZQ@33958,4IFTP@91061 NA|NA|NA GHBLAFEN_00959 326425.lhe_0062 9.6e-138 496.1 Lactobacillaceae XK27_08845 ko:K05833 M00247 ko00000,ko00002,ko02000 Bacteria 1TPAN@1239,3F3NW@33958,4HCHC@91061,COG1101@1,COG1101@2 NA|NA|NA S ABC transporter, ATP-binding protein GHBLAFEN_00960 1033837.WANG_1617 2.2e-125 455.3 Lactobacillaceae XK27_08840 ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPDJ@1239,3F40J@33958,4HBMY@91061,COG4120@1,COG4120@2 NA|NA|NA U Belongs to the binding-protein-dependent transport system permease family GHBLAFEN_00961 326425.lhe_0064 1e-176 625.9 Lactobacillaceae ABC-SBP ko:K01989,ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPB0@1239,3F462@33958,4HESK@91061,COG2984@1,COG2984@2 NA|NA|NA S ABC transporter GHBLAFEN_00962 405566.lhv_0057 9.2e-135 486.1 Lactobacillaceae yjjG GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006206,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008655,GO:0009058,GO:0009112,GO:0009410,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019856,GO:0019859,GO:0030145,GO:0034641,GO:0034654,GO:0042221,GO:0042578,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.102,3.1.3.104,3.1.3.5,3.8.1.2 ko:K01560,ko:K07025,ko:K08723,ko:K20862 ko00230,ko00240,ko00361,ko00625,ko00740,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00740,map00760,map01100,map01110,map01120 M00125 R00183,R00511,R00548,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287,R07280 RC00017,RC00697 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_4614 Bacteria 1TS3W@1239,3F4NI@33958,4HADE@91061,COG1011@1,COG1011@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase GHBLAFEN_00963 891391.LAC30SC_00345 2.1e-33 148.7 Lactobacillaceae Bacteria 1U580@1239,29NJD@1,309JD@2,3F53B@33958,4IEZA@91061 NA|NA|NA S Bacteriocin helveticin-J GHBLAFEN_00964 1033837.WANG_1620 1.1e-211 742.3 Lactobacillaceae Bacteria 1U59E@1239,29DXA@1,300V7@2,3F59A@33958,4IF0P@91061 NA|NA|NA S SLAP domain GHBLAFEN_00965 326425.lhe_0069 1.4e-164 585.5 Lactobacillaceae yvgN Bacteria 1TPM1@1239,3F3PW@33958,4HARE@91061,COG0656@1,COG0656@2 NA|NA|NA C Aldo keto reductase GHBLAFEN_00966 405566.lhv_0061 0.0 1284.6 Lactobacillaceae tetP ko:K02355 ko00000,ko03012,ko03029 Bacteria 1TPQH@1239,3F4B4@33958,4HAS9@91061,COG0480@1,COG0480@2 NA|NA|NA J elongation factor G GHBLAFEN_00967 1033837.WANG_1623 7.9e-154 549.7 Lactobacillaceae 3.1.3.102,3.1.3.104,3.1.3.23 ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R00804,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1U5C1@1239,3F5HG@33958,4IF34@91061,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase GHBLAFEN_00968 272621.LBA1859 8.4e-264 916.0 Lactobacillaceae nisT ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TPZP@1239,3F53S@33958,4HDMH@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter GHBLAFEN_00969 1033837.WANG_1626 2.5e-36 157.5 Lactobacillaceae Bacteria 1U60N@1239,29NJE@1,30RS9@2,3F6SP@33958,4IFPF@91061 NA|NA|NA GHBLAFEN_00970 405566.lhv_0734 1.1e-170 605.9 Lactobacillaceae whiA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944 ko:K09762 ko00000 Bacteria 1TP2X@1239,3F4AB@33958,4HB4H@91061,COG1481@1,COG1481@2 NA|NA|NA K May be required for sporulation GHBLAFEN_00971 405566.lhv_0733 2.9e-193 681.0 Lactobacillaceae ybhK Bacteria 1TPNV@1239,3F4D5@33958,4HA0Z@91061,COG0391@1,COG0391@2 NA|NA|NA S Required for morphogenesis under gluconeogenic growth conditions GHBLAFEN_00972 405566.lhv_0732 3.1e-164 584.3 Lactobacillaceae rapZ GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K06958 ko00000,ko03019 Bacteria 1TPS4@1239,3F4NY@33958,4H9KM@91061,COG1660@1,COG1660@2 NA|NA|NA S Displays ATPase and GTPase activities GHBLAFEN_00973 1423748.BALB01000001_gene171 9.1e-82 309.7 Lactobacillaceae Bacteria 1V759@1239,3F58J@33958,4HK5F@91061,COG3247@1,COG3247@2 NA|NA|NA S Short repeat of unknown function (DUF308) GHBLAFEN_00974 326425.lhe_0696 0.0 1881.7 Lactobacillaceae uvrA ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TPIJ@1239,3F4TZ@33958,4HAW9@91061,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate GHBLAFEN_00975 326425.lhe_0695 0.0 1328.9 Lactobacillaceae uvrB ko:K03702,ko:K08999 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TPKB@1239,3F3XM@33958,4HB81@91061,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage GHBLAFEN_00976 405566.lhv_0728 0.0 1146.7 Lactobacillaceae pgm GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2,5.4.2.8 ko:K01835,ko:K01840 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114,M00549 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP2N@1239,3F457@33958,4HADU@91061,COG1109@1,COG1109@2 NA|NA|NA G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain GHBLAFEN_00977 1033837.WANG_0964 0.0 1196.0 Lactobacillaceae malQ 2.4.1.25,3.2.1.20,3.2.1.41 ko:K00705,ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 R00028,R00801,R00802,R02111,R05196,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 CBM48,GH13,GH31,GH77 Bacteria 1TNZ0@1239,3F41N@33958,4HB67@91061,COG0366@1,COG0366@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family GHBLAFEN_00978 1033837.WANG_0965 0.0 1580.1 Lactobacillaceae glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 R02111 ko00000,ko00001,ko01000 GT35 iYO844.BSU30940 Bacteria 1TQAJ@1239,3F4Z1@33958,4H9XI@91061,COG0058@1,COG0058@2 NA|NA|NA G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties GHBLAFEN_00979 1033837.WANG_0966 4e-286 989.9 Lactobacillaceae glgA GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 GT5 Bacteria 1TQ4M@1239,3F3PP@33958,4HAVA@91061,COG0297@1,COG0297@2 NA|NA|NA F Synthesizes alpha-1,4-glucan chains using ADP-glucose GHBLAFEN_00980 1033837.WANG_0967 1.2e-216 758.8 Lactobacillaceae glgD 2.4.1.21,2.7.7.27 ko:K00703,ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948,R02421 RC00002,RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 GT5 Bacteria 1TPZ3@1239,3F58E@33958,4H9UQ@91061,COG0448@1,COG0448@2 NA|NA|NA G Nucleotidyl transferase GHBLAFEN_00981 1033837.WANG_0968 6.4e-202 709.9 Lactobacillaceae glgC 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TNZW@1239,3F4IA@33958,4HAZX@91061,COG0448@1,COG0448@2 NA|NA|NA H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans GHBLAFEN_00982 1033837.WANG_0969 0.0 1352.0 Lactobacillaceae glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,3.2.1.141,3.2.1.20 ko:K00700,ko:K01187,ko:K01236,ko:K17734 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 M00565 R00028,R00801,R00802,R02110,R06087,R06088,R09995,R11256 RC00028,RC00049,RC00077 ko00000,ko00001,ko00002,ko01000,ko01002,ko04147 CBM48,GH13,GH31 iAPECO1_1312.APECO1_3025,iECNA114_1301.ECNA114_3542,iECOK1_1307.ECOK1_3857,iECS88_1305.ECS88_3830,iECSF_1327.ECSF_3253,iJN678.glgB,iLF82_1304.LF82_0837,iNRG857_1313.NRG857_17030,iUTI89_1310.UTI89_C3941 Bacteria 1TP4M@1239,3F4KT@33958,4HAPM@91061,COG0296@1,COG0296@2 NA|NA|NA G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position GHBLAFEN_00983 1423790.BN53_00815 1.3e-41 175.6 Lactobacillaceae Bacteria 1TSH6@1239,3F5HS@33958,4HEX8@91061,COG3385@1,COG3385@2 NA|NA|NA L PFAM transposase, IS4 family protein GHBLAFEN_00984 1423748.BALB01000009_gene1024 3.7e-30 137.1 Lactobacillaceae Bacteria 1TSH6@1239,3F5HS@33958,4HEX8@91061,COG3385@1,COG3385@2 NA|NA|NA L PFAM transposase, IS4 family protein GHBLAFEN_00985 326425.lhe_0820 1.2e-76 292.4 Lactobacillaceae mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 ko:K03925 ko00000 Bacteria 1V3JD@1239,3F6K3@33958,4HH23@91061,COG2001@1,COG2001@2 NA|NA|NA K Belongs to the MraZ family GHBLAFEN_00986 326425.lhe_0821 6.3e-182 643.3 Lactobacillaceae rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 1TNZV@1239,3F3MF@33958,4H9U2@91061,COG0275@1,COG0275@2 NA|NA|NA J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA GHBLAFEN_00987 326425.lhe_0822 9.1e-54 216.1 Lactobacillaceae ftsL Bacteria 1VCE5@1239,3F6KG@33958,4HM4W@91061,COG4839@1,COG4839@2 NA|NA|NA D Cell division protein FtsL GHBLAFEN_00988 1423748.BALB01000001_gene45 0.0 1266.9 Lactobacillaceae ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 1TP93@1239,3F47N@33958,4H9VQ@91061,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein GHBLAFEN_00989 405566.lhv_0854 2.3e-176 624.8 Lactobacillaceae mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Bacteria 1TP8W@1239,3F3YP@33958,4H9TP@91061,COG0472@1,COG0472@2 NA|NA|NA M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan GHBLAFEN_00990 326425.lhe_0825 2.8e-260 904.0 Lactobacillaceae murD 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TQ3P@1239,3F49W@33958,4HA5P@91061,COG0771@1,COG0771@2 NA|NA|NA M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) GHBLAFEN_00991 405566.lhv_0856 2.3e-209 734.6 Lactobacillaceae murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 GT28 iLJ478.TM0232,iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089 Bacteria 1TQFT@1239,3F4FW@33958,4HBAQ@91061,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) GHBLAFEN_00992 405566.lhv_0857 4.4e-131 474.2 Lactobacillaceae divIB ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Bacteria 1V6V5@1239,3F406@33958,4HDFD@91061,COG1589@1,COG1589@2 NA|NA|NA D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex GHBLAFEN_00993 405566.lhv_0858 2e-234 818.1 Lactobacillaceae ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Bacteria 1TP1Z@1239,3F413@33958,4H9NF@91061,COG0849@1,COG0849@2 NA|NA|NA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring GHBLAFEN_00994 405566.lhv_0859 1.6e-204 718.8 Lactobacillaceae ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Bacteria 1TP6W@1239,3F4V1@33958,4H9WZ@91061,COG0206@1,COG0206@2 NA|NA|NA D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity GHBLAFEN_00995 1423748.BALB01000001_gene37 4.8e-73 280.4 Lactobacillaceae sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0044464,GO:0051301,GO:0071840,GO:0071944,GO:0090529 ko:K09772 ko00000,ko03036 Bacteria 1VER3@1239,3F7MQ@33958,4HKIC@91061,COG1799@1,COG1799@2 NA|NA|NA D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA GHBLAFEN_00996 326425.lhe_0831 9e-47 192.6 Lactobacillaceae yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02221 ko00000,ko02044 Bacteria 1U6JG@1239,3F818@33958,4IGBY@91061,COG0762@1,COG0762@2 NA|NA|NA S YGGT family GHBLAFEN_00997 405566.lhv_0861 1.8e-147 528.5 Lactobacillaceae ylmH ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 Bacteria 1U5V2@1239,3F48W@33958,4HD3F@91061,COG2302@1,COG2302@2 NA|NA|NA S S4 domain protein GHBLAFEN_00998 405566.lhv_0862 3e-73 282.0 Lactobacillaceae gpsB ko:K04074 ko00000,ko03036 Bacteria 1V27M@1239,3F4IN@33958,4HG80@91061,COG3599@1,COG3599@2 NA|NA|NA D DivIVA domain protein GHBLAFEN_00999 405566.lhv_0863 0.0 1903.3 Lactobacillaceae ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_0027,iPC815.YPO0475 Bacteria 1TPS7@1239,3F3X4@33958,4HAWB@91061,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) GHBLAFEN_01000 1423748.BALB01000001_gene32 2.1e-31 141.0 Lactobacillaceae cspA ko:K03704 ko00000,ko03000 Bacteria 1U6DB@1239,3F7NC@33958,4IG52@91061,COG1278@1,COG1278@2 NA|NA|NA K 'Cold-shock' DNA-binding domain GHBLAFEN_01001 326425.lhe_0836 4.4e-103 380.6 Lactobacillaceae nudF 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 iHN637.CLJU_RS05505,iSB619.SA_RS07540,iYO844.BSU23610 Bacteria 1V6F5@1239,3F53J@33958,4HII9@91061,COG0494@1,COG0494@2 NA|NA|NA L ADP-ribose pyrophosphatase GHBLAFEN_01002 326425.lhe_0837 2.1e-38 164.9 Lactobacillaceae Bacteria 1U6T4@1239,2B5KT@1,31YFV@2,3F8FY@33958,4IGKV@91061 NA|NA|NA GHBLAFEN_01003 326425.lhe_0838 8.5e-125 453.0 Lactobacillaceae mtnN 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 Bacteria 1U7WK@1239,3F4HE@33958,4HB8K@91061,COG0775@1,COG0775@2 NA|NA|NA E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively GHBLAFEN_01004 326425.lhe_0839 3.5e-216 757.3 Lactobacillaceae iscS 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TP21@1239,3F3RF@33958,4HA6H@91061,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class V GHBLAFEN_01005 326425.lhe_0840 4.1e-56 223.8 Lactobacillaceae XK27_04120 Bacteria 1VDSF@1239,2DHWG@1,32U9W@2,3F7E3@33958,4HP9N@91061 NA|NA|NA S Putative amino acid metabolism GHBLAFEN_01006 405566.lhv_0869 6.7e-220 769.6 Lactobacillaceae mnmA GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 Bacteria 1TPIZ@1239,3F4N5@33958,4HBJ6@91061,COG0482@1,COG0482@2 NA|NA|NA J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 GHBLAFEN_01007 405566.lhv_0871 7.3e-126 456.4 Lactobacillaceae pgm6 5.4.2.11,5.4.2.12 ko:K01834,ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1V7EZ@1239,3FBD9@33958,4HJCK@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family GHBLAFEN_01008 405566.lhv_0872 1e-79 303.1 Lactobacillaceae Bacteria 1VFGR@1239,3F4MD@33958,4IBSH@91061,COG0457@1,COG0457@2 NA|NA|NA S Repeat protein GHBLAFEN_01009 405566.lhv_0873 0.0 1520.4 Lactobacillaceae recD2 3.1.11.5 ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPZH@1239,3F44X@33958,4HATQ@91061,COG0507@1,COG0507@2 NA|NA|NA L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity GHBLAFEN_01010 1423748.BALB01000001_gene22 5.9e-106 390.2 Lactobacillaceae ytlR 2.7.1.91 ko:K04718 ko00600,ko01100,ko04020,ko04071,ko04072,ko04370,ko04371,ko04666,ko05152,map00600,map01100,map04020,map04071,map04072,map04370,map04371,map04666,map05152 M00100 R01926,R02976 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V7DZ@1239,3F5GQ@33958,4HBUD@91061,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain GHBLAFEN_01011 1423748.BALB01000001_gene22 1.7e-27 128.3 Lactobacillaceae ytlR 2.7.1.91 ko:K04718 ko00600,ko01100,ko04020,ko04071,ko04072,ko04370,ko04371,ko04666,ko05152,map00600,map01100,map04020,map04071,map04072,map04370,map04371,map04666,map05152 M00100 R01926,R02976 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V7DZ@1239,3F5GQ@33958,4HBUD@91061,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain GHBLAFEN_01012 1423748.BALB01000001_gene21 0.0 1091.3 Lactobacillaceae rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TQ9G@1239,3F3TT@33958,4HAAP@91061,COG0595@1,COG0595@2 NA|NA|NA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay GHBLAFEN_01013 1033837.WANG_0819 4.2e-33 146.7 Lactobacillaceae ykzG Bacteria 1VEI7@1239,3F807@33958,4HNSK@91061,COG5503@1,COG5503@2 NA|NA|NA S Belongs to the UPF0356 family GHBLAFEN_01014 326425.lhe_0848 1.7e-99 368.6 Lactobacillaceae def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 ko:K01450,ko:K01462 ko00270,ko00630,map00270,map00630 R00653 RC00165,RC00323 ko00000,ko00001,ko01000 Bacteria 1V70B@1239,3F3YH@33958,4HH0G@91061,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions GHBLAFEN_01015 1423748.BALB01000001_gene18 0.0 1212.6 Lactobacillaceae typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 ko:K06207 ko00000 Bacteria 1TQ5Y@1239,3F3UK@33958,4HAQ6@91061,COG1217@1,COG1217@2 NA|NA|NA T GTP-binding protein TypA GHBLAFEN_01016 326425.lhe_0850 1.5e-206 725.3 Lactobacillaceae ftsW ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 2.A.103.1 Bacteria 1TPT7@1239,3F4IK@33958,4HAEV@91061,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family GHBLAFEN_01017 326425.lhe_0851 8.7e-54 216.1 Lactobacillaceae ylbG Bacteria 1VF52@1239,3F70V@33958,4HNTH@91061,COG4471@1,COG4471@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2129) GHBLAFEN_01018 326425.lhe_0852 3.2e-95 354.4 Lactobacillaceae rsmD 2.1.1.171 ko:K08316 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1V3JF@1239,3F505@33958,4HGXT@91061,COG0742@1,COG0742@2 NA|NA|NA L RNA methyltransferase, RsmD family GHBLAFEN_01019 405566.lhv_0886 2.7e-85 321.2 Lactobacillaceae coaD GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0015939,GO:0015940,GO:0016043,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046390,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 iPC815.YPO0053,iSDY_1059.SDY_4064 Bacteria 1V3MR@1239,3FCD3@33958,4HH47@91061,COG0669@1,COG0669@2 NA|NA|NA H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate GHBLAFEN_01020 405566.lhv_0887 1.4e-192 678.7 Lactobacillaceae ylbL ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Bacteria 1TRUF@1239,3F4KY@33958,4HBAY@91061,COG3480@1,COG3480@2 NA|NA|NA T Belongs to the peptidase S16 family GHBLAFEN_01021 405566.lhv_0888 3.1e-82 311.6 Lactobacillaceae comEA ko:K02237 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1VA3W@1239,3F7NP@33958,4HKJ1@91061,COG1555@1,COG1555@2 NA|NA|NA L Competence protein ComEA GHBLAFEN_01022 326425.lhe_0856 0.0 1422.5 Lactobacillaceae comEC ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1TS9U@1239,3F3VT@33958,4H9M4@91061,COG0658@1,COG0658@2,COG2333@1,COG2333@2 NA|NA|NA S Competence protein ComEC GHBLAFEN_01023 326425.lhe_0857 4.8e-174 617.1 Lactobacillaceae holA 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TRM0@1239,3F3TP@33958,4HBB4@91061,COG1466@1,COG1466@2 NA|NA|NA L DNA polymerase III delta subunit GHBLAFEN_01024 272621.LBA0841 1.5e-34 151.8 Lactobacillaceae rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02968 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEGX@1239,3F7D8@33958,4HNJS@91061,COG0268@1,COG0268@2 NA|NA|NA J Binds directly to 16S ribosomal RNA GHBLAFEN_01025 1423748.BALB01000001_gene8 7e-43 179.5 Lactobacillaceae rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VA5C@1239,3F7DV@33958,4HKE9@91061,COG0184@1,COG0184@2 NA|NA|NA J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome GHBLAFEN_01026 405566.lhv_0893 0.0 1095.9 Lactobacillaceae rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TQ9G@1239,3F3U9@33958,4HAAP@91061,COG0595@1,COG0595@2 NA|NA|NA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay GHBLAFEN_01027 405566.lhv_0894 2.4e-150 538.1 Lactobacillaceae Bacteria 1TW9B@1239,2CC00@1,30489@2,3F52A@33958,4I50I@91061 NA|NA|NA GHBLAFEN_01028 1423748.BALB01000001_gene5 4.7e-224 783.5 Lactobacillaceae tuf GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 ko:K02358,ko:K15771 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 Bacteria 1TPKC@1239,3F3ZP@33958,4HAEH@91061,COG0050@1,COG0050@2 NA|NA|NA J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis GHBLAFEN_01029 326425.lhe_0863 1.5e-207 728.8 Lactobacillaceae tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K03545 ko00000 Bacteria 1TQQ8@1239,3F40B@33958,4H9Q8@91061,COG0544@1,COG0544@2 NA|NA|NA D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase GHBLAFEN_01030 326425.lhe_0864 4.5e-233 813.5 Lactobacillaceae clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 1TQ00@1239,3F41K@33958,4H9U4@91061,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP GHBLAFEN_01031 405566.lhv_0898 5.4e-104 383.6 Lactobacillaceae engB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03978 ko00000,ko03036 Bacteria 1TSPW@1239,3F44G@33958,4HBXZ@91061,COG0218@1,COG0218@2 NA|NA|NA D Necessary for normal cell division and for the maintenance of normal septation GHBLAFEN_01032 891391.LAC30SC_04260 1.3e-271 941.8 Lactobacillaceae yjeM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1TRFS@1239,3F4J0@33958,4HA0N@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid GHBLAFEN_01033 405566.lhv_0902 9.2e-189 666.0 Lactobacillaceae dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMN@1239,3F4F7@33958,4HBH4@91061,COG0253@1,COG0253@2 NA|NA|NA E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan GHBLAFEN_01034 326425.lhe_0868 1.9e-261 907.9 Lactobacillaceae lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iYO844.BSU03790 Bacteria 1TPQJ@1239,3F48V@33958,4HAEP@91061,COG0527@1,COG0527@2 NA|NA|NA E Belongs to the aspartokinase family GHBLAFEN_01035 405566.lhv_0905 9.4e-250 869.0 Lactobacillaceae lysA 4.1.1.19,4.1.1.20 ko:K01585,ko:K01586 ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map01100,map01110,map01120,map01130,map01230 M00016,M00133,M00525,M00526,M00527 R00451,R00566 RC00299 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS18870 Bacteria 1TPE9@1239,3F3VJ@33958,4H9XW@91061,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine GHBLAFEN_01036 326425.lhe_0870 3.6e-78 298.1 Lactobacillaceae dapD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 iSbBS512_1146.SbBS512_E0158,iYO844.BSU14180 Bacteria 1TQUJ@1239,3F3U0@33958,4H9KY@91061,COG2171@1,COG2171@2 NA|NA|NA E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate GHBLAFEN_01037 405566.lhv_0907 4e-220 770.4 Lactobacillaceae hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823,ko:K21613 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPD7@1239,3F419@33958,4H9SG@91061,COG1473@1,COG1473@2 NA|NA|NA E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate GHBLAFEN_01038 326425.lhe_0872 2.7e-174 617.8 Lactobacillaceae dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCK@1239,3F4UH@33958,4H9K9@91061,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) GHBLAFEN_01039 326425.lhe_0873 8.6e-142 509.6 Lactobacillaceae dapB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 iJN678.dapB,iNJ661.Rv2773c,iYO844.BSU22490 Bacteria 1TR9D@1239,3F3MA@33958,4HA5X@91061,COG0289@1,COG0289@2 NA|NA|NA E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate GHBLAFEN_01040 326425.lhe_0874 1.8e-212 745.0 Lactobacillaceae aspC 2.6.1.1 ko:K00812,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00525 R00355,R00694,R00734,R00896,R02433,R02619,R04467,R05052 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase GHBLAFEN_01041 405566.lhv_0911 1.5e-197 695.3 Lactobacillaceae asd 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC6@1239,3F4S9@33958,4HA9H@91061,COG0136@1,COG0136@2 NA|NA|NA E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate GHBLAFEN_01042 405566.lhv_0912 9.1e-206 722.6 Lactobacillaceae pbpX1 Bacteria 1V4BS@1239,3F3QN@33958,4HJRT@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase GHBLAFEN_01043 1423748.BALB01000019_gene1577 5.3e-110 403.7 Lactobacillaceae 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1U7WX@1239,3F4BS@33958,4HHQT@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain GHBLAFEN_01044 405566.lhv_0914 3.5e-299 1033.5 Lactobacillaceae Bacteria 1UHVZ@1239,3F5G1@33958,4ISGG@91061,COG2267@1,COG2267@2 NA|NA|NA I Protein of unknown function (DUF2974) GHBLAFEN_01045 1423748.BALB01000019_gene1575 8.3e-36 156.0 Lactobacillaceae Bacteria 1TR5A@1239,3F7II@33958,4IT3F@91061,COG3976@1,COG3976@2 NA|NA|NA C FMN_bind GHBLAFEN_01046 326425.lhe_0880 4.3e-10 69.3 Lactobacillaceae Bacteria 1UFVR@1239,2F7PX@1,34049@2,3F548@33958,4IEZD@91061 NA|NA|NA GHBLAFEN_01047 405566.lhv_0917 6.1e-55 219.9 Lactobacillaceae Bacteria 1UFVR@1239,2F7PX@1,34049@2,3F548@33958,4IEZD@91061 NA|NA|NA GHBLAFEN_01048 405566.lhv_0918 1e-173 615.9 Lactobacillaceae iunH 3.2.2.1 ko:K01239,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 Bacteria 1TRGU@1239,3F3V1@33958,4H9TZ@91061,COG1957@1,COG1957@2 NA|NA|NA F inosine-uridine preferring nucleoside hydrolase GHBLAFEN_01049 326425.lhe_0882 3.9e-170 604.0 Lactobacillaceae Bacteria 1TQ12@1239,3F4U1@33958,4HA57@91061,COG4989@1,COG4989@2 NA|NA|NA S Aldo keto reductase GHBLAFEN_01050 1423748.BALB01000019_gene1571 4.5e-242 843.6 Lactobacillaceae celA 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family GHBLAFEN_01051 748671.LCRIS_00896 2.8e-123 448.0 Lactobacillaceae gmuR ko:K03492,ko:K03710 ko00000,ko03000 Bacteria 1V0UW@1239,3FC8M@33958,4HD10@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA GHBLAFEN_01052 1033837.WANG_1183 1.3e-162 578.9 Lactobacillaceae uvrX 2.7.7.7 ko:K02346,ko:K03502,ko:K14161 ko00000,ko01000,ko03400 Bacteria 1TP42@1239,3F3WN@33958,4HA1P@91061,COG0389@1,COG0389@2 NA|NA|NA L Belongs to the DNA polymerase type-Y family GHBLAFEN_01053 353496.LBU_0899 4.1e-192 677.2 Lactobacillaceae add 3.5.4.2,3.5.4.4 ko:K01488,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 R01244,R01560,R02556 RC00477 ko00000,ko00001,ko01000 Bacteria 1U44B@1239,3F5RC@33958,4HCES@91061,COG1816@1,COG1816@2 NA|NA|NA F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism GHBLAFEN_01054 353496.LBU_0900 1.3e-235 822.0 Lactobacillaceae pbuG ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 1TQC6@1239,3F44D@33958,4HANG@91061,COG2252@1,COG2252@2 NA|NA|NA S permease GHBLAFEN_01055 353496.LBU_0901 0.0 1181.8 Lactobacillaceae ade 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 R01244 RC00477 ko00000,ko00001,ko01000 Bacteria 1TP84@1239,3F4BJ@33958,4HBB2@91061,COG1001@1,COG1001@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family GHBLAFEN_01056 1423748.BALB01000015_gene1366 6.6e-42 176.4 Lactobacillaceae Bacteria 1UI8X@1239,3FBSZ@33958,4ISGE@91061,COG2461@1,COG2461@2 NA|NA|NA S PAS domain GHBLAFEN_01057 1033837.WANG_0780 1.3e-134 485.7 Lactobacillaceae nirC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K02598,ko:K06212,ko:K21993 ko00000,ko02000 1.A.16.1.1,1.A.16.1.3,1.A.16.2,1.A.16.3 iSF_1195.SF3386,iS_1188.S4377 Bacteria 1TRTT@1239,3F4JG@33958,4HEWN@91061,COG2116@1,COG2116@2 NA|NA|NA P Formate/nitrite transporter GHBLAFEN_01058 748671.LCRIS_01831 8.8e-144 516.5 Lactobacillaceae glcD2 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 R00475 RC00042 ko00000,ko00001,ko01000 Bacteria 1TPBC@1239,3F4AD@33958,4H9UU@91061,COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidases, C-terminal domain GHBLAFEN_01059 1423790.BN53_02275 1.2e-54 219.2 Lactobacillaceae glcD2 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 R00475 RC00042 ko00000,ko00001,ko01000 Bacteria 1TPBC@1239,3F4AD@33958,4H9UU@91061,COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidases, C-terminal domain GHBLAFEN_01060 1033837.WANG_0779 7.5e-108 396.4 Lactobacillaceae pncA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 ko:K16788 ko00000,ko02000 2.A.88.5 iSB619.SA_RS09955 Bacteria 1V1CY@1239,3F41F@33958,4HFRS@91061,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family GHBLAFEN_01061 1033837.WANG_0778 1.1e-267 928.7 Lactobacillaceae pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 Bacteria 1TPDW@1239,3F3K7@33958,4HAI4@91061,COG1488@1,COG1488@2 NA|NA|NA F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP GHBLAFEN_01062 405566.lhv_0934 5.4e-127 460.3 Lactobacillaceae 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 1TST7@1239,3F54T@33958,4HEFP@91061,COG1051@1,COG1051@2,COG4111@1,COG4111@2 NA|NA|NA F NUDIX domain GHBLAFEN_01064 1033837.WANG_0775 2.1e-72 278.1 Lactobacillaceae Bacteria 1U5KS@1239,2F916@1,309SE@2,3F65Y@33958,4IFBR@91061 NA|NA|NA S Iron-sulphur cluster biosynthesis GHBLAFEN_01065 1071400.LBUCD034_0849 8.6e-41 172.6 Lactobacillaceae gcvR ko:K07166 ko00000 Bacteria 1VENW@1239,3F811@33958,4HNJ4@91061,COG3830@1,COG3830@2 NA|NA|NA T Belongs to the UPF0237 family GHBLAFEN_01066 405566.lhv_0606 2.9e-246 857.4 Lactobacillaceae XK27_08635 ko:K09157 ko00000 Bacteria 1TQG8@1239,3F4H2@33958,4HBTU@91061,COG2848@1,COG2848@2 NA|NA|NA S UPF0210 protein GHBLAFEN_01067 1071400.LBUCD034_1016 3.8e-53 214.5 Lactobacillaceae tnp2PF3 Bacteria 1U5ZT@1239,3F6RW@33958,4IFNT@91061,COG3293@1,COG3293@2 NA|NA|NA L Putative transposase of IS4/5 family (DUF4096) GHBLAFEN_01068 326425.lhe_0400 2.5e-140 505.0 Lactobacillaceae ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1V5H7@1239,3FBE5@33958,4HMYU@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family GHBLAFEN_01071 405566.lhv_1808 3.3e-199 701.0 Lactobacillaceae hflX ko:K03665 ko00000,ko03009 Bacteria 1TNZB@1239,3F4B2@33958,4HACA@91061,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis GHBLAFEN_01073 405566.lhv_1807 2.2e-180 638.3 Lactobacillaceae brpA Bacteria 1TR1B@1239,3F3MQ@33958,4HA09@91061,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-like function transcriptional attenuator common domain protein GHBLAFEN_01074 405566.lhv_1806 2.5e-145 521.5 Lactobacillaceae epsB Bacteria 1UZCR@1239,3F4M5@33958,4HE26@91061,COG3944@1,COG3944@2 NA|NA|NA M biosynthesis protein GHBLAFEN_01075 326425.lhe_0405 5.4e-120 437.2 Lactobacillaceae ywqD 2.7.10.1 ko:K08252,ko:K16554 ko05111,map05111 ko00000,ko00001,ko01000,ko02000 8.A.3.1 Bacteria 1TS4R@1239,3F4BM@33958,4HCEN@91061,COG0489@1,COG0489@2 NA|NA|NA D Capsular exopolysaccharide family GHBLAFEN_01076 326425.lhe_0406 4.8e-145 520.4 Lactobacillaceae ywqE 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1TQ1T@1239,3F3RT@33958,4HDZR@91061,COG4464@1,COG4464@2 NA|NA|NA GM PHP domain protein GHBLAFEN_01077 405566.lhv_1803 8.2e-122 443.0 Lactobacillaceae rfbP Bacteria 1TP7M@1239,3FB5K@33958,4HHDH@91061,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase GHBLAFEN_01078 326425.lhe_0409 1e-194 686.0 Lactobacillaceae rgpAc ko:K12996 ko00000,ko01000,ko01003,ko01005 GT4 Bacteria 1TR0Y@1239,3F5EQ@33958,4IPU2@91061,COG0438@1,COG0438@2 NA|NA|NA M Domain of unknown function (DUF1972) GHBLAFEN_01079 1423747.BAMJ01000024_gene1578 5e-106 391.3 Lactobacillaceae wcoF Bacteria 1TR6R@1239,3F7BB@33958,4HEIZ@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 GHBLAFEN_01080 334390.LAF_1414 1.2e-29 137.5 Lactobacillaceae GO:0003674,GO:0003824,GO:0016740,GO:0016757 ko:K12983 ko00000,ko01000,ko01003,ko01005 GT2 Bacteria 1V0TF@1239,3FBRX@33958,4HVF8@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 GHBLAFEN_01081 326425.lhe_0414 1.1e-60 240.4 Lactobacillaceae ko:K07011 ko00000 Bacteria 1VAE1@1239,3F941@33958,4HM9Y@91061,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 GHBLAFEN_01082 1437610.BREU_0823 3.8e-61 242.3 Actinobacteria Bacteria 2IFGX@201174,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 GHBLAFEN_01083 1116231.SMA_0869 4.8e-38 165.6 Bacilli Bacteria 1U49M@1239,2ATWB@1,31JFJ@2,4HZJD@91061 NA|NA|NA GHBLAFEN_01084 326425.lhe_1848 4.7e-194 683.7 Lactobacillaceae Bacteria 1U56A@1239,2DKI3@1,309IT@2,3F4WY@33958,4IEXK@91061 NA|NA|NA S SLAP domain GHBLAFEN_01085 326425.lhe_1847 5.1e-176 623.6 Lactobacillaceae prs 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2848 Bacteria 1TQ6Q@1239,3F3U2@33958,4HB61@91061,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) GHBLAFEN_01086 1423748.BALB01000008_gene964 5.5e-148 530.4 Lactobacillaceae Bacteria 1TRQ7@1239,3F3ZI@33958,4HE30@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family GHBLAFEN_01087 326425.lhe_1845 5.5e-43 179.9 Lactobacillaceae Bacteria 1U6GK@1239,29PEC@1,30ACI@2,3F7VQ@33958,4IG8S@91061 NA|NA|NA GHBLAFEN_01088 326425.lhe_1844 4.7e-268 929.9 Lactobacillaceae ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 ko:K06885 ko00000 Bacteria 1TPVB@1239,3FC99@33958,4IQRC@91061,COG1078@1,COG1078@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. GHBLAFEN_01089 326425.lhe_1843 3.6e-67 260.8 Lactobacillaceae Bacteria 1U64K@1239,29P4Y@1,30A35@2,3F712@33958,4IFU4@91061 NA|NA|NA S Domain of unknown function (DUF1934) GHBLAFEN_01090 326425.lhe_1842 1.5e-47 196.1 Lactobacillaceae rpoE GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Bacteria 1V6WX@1239,3F55D@33958,4HIUK@91061,COG3343@1,COG3343@2 NA|NA|NA K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling GHBLAFEN_01091 326425.lhe_1841 0.0 1082.8 Lactobacillaceae pyrG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS01075,iNJ661.Rv1699 Bacteria 1TP34@1239,3F42X@33958,4H9X6@91061,COG0504@1,COG0504@2 NA|NA|NA F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates GHBLAFEN_01092 405566.lhv_0248 8.1e-246 855.9 Lactobacillaceae murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 iYO844.BSU37100 Bacteria 1TPAU@1239,3F3P8@33958,4H9KI@91061,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine GHBLAFEN_01093 1423748.BALB01000008_gene975 3.7e-33 147.1 Lactobacillaceae GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0044237,GO:0050308,GO:0050309 Bacteria 1V1N8@1239,3F8H8@33958,4HG58@91061,COG0637@1,COG0637@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase GHBLAFEN_01094 405566.lhv_0249 4.4e-49 200.3 Lactobacillaceae GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0044237,GO:0050308,GO:0050309 Bacteria 1V1N8@1239,3F8H8@33958,4HG58@91061,COG0637@1,COG0637@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase GHBLAFEN_01095 405566.lhv_0250 4.8e-284 983.0 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase GHBLAFEN_01096 326425.lhe_1837 2e-157 561.6 Lactobacillaceae msmR Bacteria 1V8G6@1239,3FBER@33958,4HIF6@91061,COG2207@1,COG2207@2 NA|NA|NA K AraC-like ligand binding domain GHBLAFEN_01097 1033837.WANG_1860 4.9e-219 766.9 Lactobacillaceae pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 ko:K02824,ko:K03458,ko:K16169,ko:K16170 ko00000,ko02000 2.A.40,2.A.40.1.1,2.A.40.1.2,2.A.40.3.1,2.A.40.3.2 iSB619.SA_RS02140 Bacteria 1TNZZ@1239,3F3Y7@33958,4HBAM@91061,COG2233@1,COG2233@2 NA|NA|NA F xanthine permease GHBLAFEN_01098 326425.lhe_1835 7.4e-98 363.2 Lactobacillaceae xpt GO:0003674,GO:0003824,GO:0006139,GO:0006166,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046128,GO:0046129,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816,ko:K09685 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko03000,ko04147 iYO844.BSU22070 Bacteria 1V1DU@1239,3F49S@33958,4HFNW@91061,COG0503@1,COG0503@2 NA|NA|NA F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis GHBLAFEN_01099 326425.lhe_1834 1.9e-112 412.1 Lactobacillaceae Bacteria 1V36C@1239,3F65G@33958,4IT3D@91061,COG1476@1,COG1476@2 NA|NA|NA K DNA-binding helix-turn-helix protein GHBLAFEN_01100 1423748.BALB01000008_gene981 1.4e-17 96.3 Lactobacillaceae Bacteria 1UHWD@1239,3FBYR@33958,4IU4I@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix GHBLAFEN_01101 326425.lhe_1830 1e-303 1048.5 Lactobacillaceae guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 ko:K01951,ko:K03790 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002,ko03009 iLJ478.TM1820 Bacteria 1TPG8@1239,3F3NV@33958,4HA7Q@91061,COG0519@1,COG0519@2 NA|NA|NA F Catalyzes the synthesis of GMP from XMP GHBLAFEN_01102 326425.lhe_0736 4.6e-91 340.5 Lactobacillaceae Bacteria 1VF6Q@1239,3F57S@33958,4HMDE@91061,COG5652@1,COG5652@2 NA|NA|NA S VanZ like family GHBLAFEN_01103 326425.lhe_0737 8.9e-133 479.6 Lactobacillaceae yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 Bacteria 1TPP5@1239,3F4WF@33958,4H9WJ@91061,COG0217@1,COG0217@2 NA|NA|NA K Transcriptional regulatory protein GHBLAFEN_01104 326425.lhe_0738 2.7e-177 627.9 Lactobacillaceae comGA ko:K02243 M00429 ko00000,ko00002,ko02044 3.A.14.1 Bacteria 1TPGE@1239,3F4HY@33958,4HB0C@91061,COG2804@1,COG2804@2 NA|NA|NA NU Type II IV secretion system protein GHBLAFEN_01105 326425.lhe_0739 7.6e-175 619.8 Lactobacillaceae comGB ko:K02244 M00429 ko00000,ko00002,ko02044 3.A.14.1 Bacteria 1U00C@1239,3F3S9@33958,4HGUA@91061,COG1459@1,COG1459@2 NA|NA|NA NU type II secretion system GHBLAFEN_01106 326425.lhe_0740 3.7e-44 184.1 Lactobacillaceae comGC GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 ko:K02245,ko:K02456 ko03070,ko05111,map03070,map05111 M00331,M00429 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1VFI9@1239,3F7ZC@33958,4HNNT@91061,COG4537@1,COG4537@2 NA|NA|NA U competence protein ComGC GHBLAFEN_01107 326425.lhe_0741 2.1e-73 281.6 Lactobacillaceae ko:K02246 M00429 ko00000,ko00002,ko02044 Bacteria 1U645@1239,29ZCH@1,30MB3@2,3F6ZT@33958,4IFTR@91061 NA|NA|NA GHBLAFEN_01108 326425.lhe_0742 1e-41 175.6 Lactobacillaceae Bacteria 1U6G6@1239,2BS3U@1,32M4K@2,3F7UI@33958,4IG89@91061 NA|NA|NA GHBLAFEN_01109 326425.lhe_0743 8.4e-82 309.7 Lactobacillaceae comGF ko:K02246,ko:K02248 M00429 ko00000,ko00002,ko02044 Bacteria 1U6NI@1239,3F87B@33958,4IGFH@91061,COG4940@1,COG4940@2 NA|NA|NA U Putative Competence protein ComGF GHBLAFEN_01110 405566.lhv_0784 3.9e-187 660.6 Lactobacillaceae ytxK 2.1.1.72 ko:K00571 ko00000,ko01000,ko02048 Bacteria 1TRIQ@1239,3F4CI@33958,4H9SE@91061,COG0827@1,COG0827@2 NA|NA|NA L N-6 DNA Methylase GHBLAFEN_01111 326425.lhe_0745 6.8e-223 779.6 Lactobacillaceae ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0409 Bacteria 1TQ22@1239,3F48Z@33958,4HA7K@91061,COG0282@1,COG0282@2 NA|NA|NA F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction GHBLAFEN_01113 748671.LCRIS_00747 2.4e-34 151.4 Lactobacillaceae Bacteria 1TQXN@1239,3F4Y5@33958,4HBHT@91061,COG5434@1,COG5434@2 NA|NA|NA M Protein of unknown function (DUF3737) GHBLAFEN_01114 748671.LCRIS_00747 2.1e-32 144.8 Lactobacillaceae Bacteria 1TQXN@1239,3F4Y5@33958,4HBHT@91061,COG5434@1,COG5434@2 NA|NA|NA M Protein of unknown function (DUF3737) GHBLAFEN_01115 405566.lhv_0788 2.4e-225 787.7 Lactobacillaceae patB 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 Bacteria 1TP5G@1239,3F4JX@33958,4H9PE@91061,COG1168@1,COG1168@2 NA|NA|NA E Aminotransferase, class I GHBLAFEN_01116 326425.lhe_0749 3.3e-167 594.3 Lactobacillaceae manA 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 1VRGI@1239,3F40I@33958,4HBFW@91061,COG1482@1,COG1482@2 NA|NA|NA G mannose-6-phosphate isomerase GHBLAFEN_01117 326425.lhe_0750 2.4e-60 238.0 Lactobacillaceae Bacteria 1VKM4@1239,2ZY3R@2,3F6IB@33958,4I0CM@91061,COG5658@1 NA|NA|NA S SdpI/YhfL protein family GHBLAFEN_01118 405566.lhv_0790 1.6e-129 468.8 Lactobacillaceae Bacteria 1TPZ0@1239,3FC92@33958,4HA7D@91061,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C terminal GHBLAFEN_01119 405566.lhv_0791 4.1e-270 936.8 Lactobacillaceae yclK 2.7.13.3 ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQ1H@1239,3FBSR@33958,4IS6U@91061,COG5000@1,COG5000@2,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase GHBLAFEN_01120 326425.lhe_0753 0.0 1387.9 Lactobacillaceae ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 R05081,R10849 RC00017 ko00000,ko00001,ko01000 Bacteria 1TRMA@1239,3F3R7@33958,4H9S0@91061,COG1368@1,COG1368@2 NA|NA|NA M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily GHBLAFEN_01121 326425.lhe_0754 8.3e-108 396.4 Lactobacillaceae vanZ Bacteria 1VK3A@1239,3F5EN@33958,4HPCD@91061,COG4767@1,COG4767@2 NA|NA|NA V VanZ like family GHBLAFEN_01122 326425.lhe_0755 2.1e-260 904.4 Lactobacillaceae pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 iLJ478.TM1385 Bacteria 1TP29@1239,3F3XK@33958,4H9VI@91061,COG0166@1,COG0166@2 NA|NA|NA G Belongs to the GPI family GHBLAFEN_01123 1033837.WANG_1903 4.4e-49 200.3 Lactobacillaceae rpsJ GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 ko:K02946 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6C9@1239,3F6KC@33958,4HIKH@91061,COG0051@1,COG0051@2 NA|NA|NA J Involved in the binding of tRNA to the ribosomes GHBLAFEN_01124 1423748.BALB01000002_gene329 4.4e-112 410.6 Lactobacillaceae rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 ko:K02906 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPFT@1239,3F45I@33958,4HAEN@91061,COG0087@1,COG0087@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit GHBLAFEN_01125 405566.lhv_0313 2.3e-105 388.3 Lactobacillaceae rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02926,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPGW@1239,3F3QD@33958,4HB01@91061,COG0088@1,COG0088@2 NA|NA|NA J Forms part of the polypeptide exit tunnel GHBLAFEN_01126 326425.lhe_1787 4.1e-47 193.7 Lactobacillaceae rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02892 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VA4W@1239,3F6Z2@33958,4HKCV@91061,COG0089@1,COG0089@2 NA|NA|NA J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome GHBLAFEN_01127 405566.lhv_0315 2.3e-153 548.1 Lactobacillaceae rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02886 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TP9X@1239,3F3XI@33958,4HAE8@91061,COG0090@1,COG0090@2 NA|NA|NA J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity GHBLAFEN_01128 1423748.BALB01000002_gene325 9.3e-46 189.1 Lactobacillaceae rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02965 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6CX@1239,3F6XP@33958,4HIG0@91061,COG0185@1,COG0185@2 NA|NA|NA J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA GHBLAFEN_01129 1423767.BALU01000004_gene1270 4e-54 217.2 Lactobacillaceae rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02890 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6PU@1239,3F6K6@33958,4HIK2@91061,COG0091@1,COG0091@2 NA|NA|NA J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome GHBLAFEN_01130 326425.lhe_1783 5.4e-108 397.1 Lactobacillaceae rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02982 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPCP@1239,3F3Q8@33958,4HAUR@91061,COG0092@1,COG0092@2 NA|NA|NA J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation GHBLAFEN_01131 1423748.BALB01000002_gene322 2.1e-76 291.6 Lactobacillaceae rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02878 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1AY@1239,3F653@33958,4HFPN@91061,COG0197@1,COG0197@2 NA|NA|NA J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs GHBLAFEN_01132 405566.lhv_0320 1.3e-25 121.7 Lactobacillaceae rpmC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02904 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEME@1239,3F82Z@33958,4HNUP@91061,COG0255@1,COG0255@2 NA|NA|NA J Belongs to the universal ribosomal protein uL29 family GHBLAFEN_01133 1423748.BALB01000002_gene320 5e-41 173.3 Lactobacillaceae rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02961 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9YC@1239,3F7FX@33958,4HKDN@91061,COG0186@1,COG0186@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA GHBLAFEN_01134 1423748.BALB01000002_gene319 1.5e-59 235.3 Lactobacillaceae rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02874 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3N0@1239,3F6GT@33958,4HGYR@91061,COG0093@1,COG0093@2 NA|NA|NA J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome GHBLAFEN_01135 405566.lhv_0323 1.7e-32 144.8 Lactobacillaceae rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02895 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9ZQ@1239,3F6X5@33958,4HKH9@91061,COG0198@1,COG0198@2 NA|NA|NA J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit GHBLAFEN_01136 405566.lhv_0324 3.6e-94 350.9 Lactobacillaceae rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02931 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPE0@1239,3F3Q7@33958,4HBAX@91061,COG0094@1,COG0094@2 NA|NA|NA J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits GHBLAFEN_01137 1423748.BALB01000002_gene316 8.9e-29 132.1 Lactobacillaceae rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEF6@1239,3FB5M@33958,4HNKX@91061,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site GHBLAFEN_01138 1423748.BALB01000002_gene315 7.2e-68 263.1 Lactobacillaceae rpsH GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904 ko:K02994 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3KK@1239,3F64E@33958,4HH32@91061,COG0096@1,COG0096@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit GHBLAFEN_01139 405566.lhv_0327 9.5e-92 342.8 Lactobacillaceae rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02933 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1FC@1239,3F4G5@33958,4HFQD@91061,COG0097@1,COG0097@2 NA|NA|NA J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center GHBLAFEN_01140 1423748.BALB01000002_gene313 2.8e-55 221.1 Lactobacillaceae rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02881 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6DM@1239,3F6KN@33958,4HIGF@91061,COG0256@1,COG0256@2 NA|NA|NA J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance GHBLAFEN_01141 1423748.BALB01000002_gene312 1.8e-84 318.5 Lactobacillaceae rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02988 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1B1@1239,3F3VY@33958,4HFN4@91061,COG0098@1,COG0098@2 NA|NA|NA J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body GHBLAFEN_01142 326425.lhe_1771 1.5e-23 114.8 Lactobacillaceae rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02907 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEG4@1239,3F7ZU@33958,4HNHF@91061,COG1841@1,COG1841@2 NA|NA|NA J Ribosomal protein L30 GHBLAFEN_01143 1423748.BALB01000002_gene310 1.5e-71 275.4 Lactobacillaceae rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02876 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3KE@1239,3F675@33958,4HFPW@91061,COG0200@1,COG0200@2 NA|NA|NA J Binds to the 23S rRNA GHBLAFEN_01144 326425.lhe_1769 4e-237 827.0 Lactobacillaceae secY GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0040007,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5 Bacteria 1TPHB@1239,3F4FV@33958,4HAWH@91061,COG0201@1,COG0201@2 NA|NA|NA U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently GHBLAFEN_01145 405566.lhv_0333 2.7e-120 438.0 Lactobacillaceae adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS20110 Bacteria 1TP27@1239,3F3KB@33958,4HA89@91061,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism GHBLAFEN_01146 1423748.BALB01000002_gene307 8.4e-34 149.1 Lactobacillaceae infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009986,GO:0016020,GO:0030246,GO:0030247,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 1V9ZK@1239,3F7CW@33958,4HKF4@91061,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex GHBLAFEN_01147 1423748.BALB01000002_gene306 7.8e-15 85.1 Lactobacillaceae rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02919 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VK4F@1239,3F8TC@33958,4HR2X@91061,COG0257@1,COG0257@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL36 family GHBLAFEN_01148 1423748.BALB01000002_gene305 4.2e-56 223.8 Lactobacillaceae rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02952 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3JH@1239,3F6GN@33958,4HGX6@91061,COG0099@1,COG0099@2 NA|NA|NA J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits GHBLAFEN_01149 1033837.WANG_0019 3e-63 247.7 Lactobacillaceae rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02948 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3IK@1239,3F67D@33958,4HH2T@91061,COG0100@1,COG0100@2 NA|NA|NA J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome GHBLAFEN_01150 405566.lhv_0337 1.8e-170 605.1 Lactobacillaceae rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TPR8@1239,3F3W6@33958,4H9R1@91061,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates GHBLAFEN_01151 1423748.BALB01000002_gene302 1.4e-60 238.8 Lactobacillaceae rplQ GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02879,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6JQ@1239,3F6GJ@33958,4HGX2@91061,COG0203@1,COG0203@2 NA|NA|NA J Ribosomal protein L17 GHBLAFEN_01152 326425.lhe_1762 1.7e-151 542.0 Lactobacillaceae ecfA1 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 ko:K01990,ko:K16784,ko:K16786,ko:K16787 ko02010,map02010 M00254,M00581,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPH8@1239,3F3VD@33958,4H9R8@91061,COG1122@1,COG1122@2 NA|NA|NA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates GHBLAFEN_01153 326425.lhe_1761 4e-150 537.3 Lactobacillaceae ecfA GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008144,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032217,GO:0032218,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035461,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0097159,GO:0097367,GO:0098656,GO:1901265,GO:1901363 3.6.3.55 ko:K01990,ko:K02068,ko:K06857,ko:K16784,ko:K16786,ko:K16787 ko02010,map02010 M00186,M00211,M00254,M00581,M00582 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35,3.A.1.6.2,3.A.1.6.4 Bacteria 1TPH8@1239,3F48E@33958,4HA7T@91061,COG1122@1,COG1122@2 NA|NA|NA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates GHBLAFEN_01154 405566.lhv_0341 1.8e-139 501.9 Lactobacillaceae ecfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 ko:K02008,ko:K16783,ko:K16785 ko02010,map02010 M00245,M00246,M00581,M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TQ0E@1239,3F3UW@33958,4H9VT@91061,COG0619@1,COG0619@2 NA|NA|NA U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates GHBLAFEN_01155 405566.lhv_0342 6e-143 513.5 Lactobacillaceae truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 1TQUY@1239,3F4KC@33958,4HCFI@91061,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs GHBLAFEN_01156 1423748.BALB01000002_gene296 1.3e-78 298.9 Lactobacillaceae rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3HX@1239,3F696@33958,4HG0I@91061,COG0102@1,COG0102@2 NA|NA|NA J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly GHBLAFEN_01157 1423748.BALB01000002_gene295 7.9e-67 259.6 Lactobacillaceae rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3MQ@1239,3F656@33958,4HH3B@91061,COG0103@1,COG0103@2 NA|NA|NA J Belongs to the universal ribosomal protein uS9 family GHBLAFEN_01158 326425.lhe_0595 3e-153 547.7 Lactobacillaceae Bacteria 1V2JE@1239,3F3Z7@33958,4HWAW@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase GHBLAFEN_01159 1423767.BALU01000018_gene1967 2.9e-54 218.0 Lactobacillaceae aacC 2.3.1.81 ko:K00662 ko00000,ko01000,ko01504 Bacteria 1V2QD@1239,3F635@33958,4HC3S@91061,COG2746@1,COG2746@2 NA|NA|NA V Aminoglycoside 3-N-acetyltransferase GHBLAFEN_01160 1423767.BALU01000018_gene1967 3.3e-62 244.6 Lactobacillaceae aacC 2.3.1.81 ko:K00662 ko00000,ko01000,ko01504 Bacteria 1V2QD@1239,3F635@33958,4HC3S@91061,COG2746@1,COG2746@2 NA|NA|NA V Aminoglycoside 3-N-acetyltransferase GHBLAFEN_01161 891391.LAC30SC_10205 3.7e-17 95.1 Lactobacillaceae ropB Bacteria 1UUY5@1239,3F7J8@33958,4I403@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix domain GHBLAFEN_01162 1423748.BALB01000004_gene561 5.7e-132 476.9 Lactobacillaceae gntR ko:K03710 ko00000,ko03000 Bacteria 1TTCD@1239,3F4DA@33958,4HEXQ@91061,COG2188@1,COG2188@2 NA|NA|NA K UbiC transcription regulator-associated domain protein GHBLAFEN_01163 405566.lhv_0614 4.8e-176 623.6 Lactobacillaceae rihB 3.2.2.1 ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 Bacteria 1TSSS@1239,3F4T0@33958,4HB17@91061,COG1957@1,COG1957@2 NA|NA|NA F Nucleoside GHBLAFEN_01164 405566.lhv_0613 0.0 1284.2 Lactobacillaceae kup GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 ko:K03549 ko00000,ko02000 2.A.72 Bacteria 1TRUQ@1239,3F4CU@33958,4HA8Z@91061,COG3158@1,COG3158@2 NA|NA|NA P Transport of potassium into the cell GHBLAFEN_01165 405566.lhv_0612 2.6e-126 458.0 Lactobacillaceae rpiA GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,2.7.1.15,5.3.1.6 ko:K00851,ko:K00852,ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01051,R01056,R01737,R02750 RC00002,RC00017,RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria 1V1DB@1239,3F43N@33958,4HFQ7@91061,COG0120@1,COG0120@2 NA|NA|NA G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate GHBLAFEN_01166 326425.lhe_0602 5.9e-166 590.1 Lactobacillaceae rbsK 2.7.1.15 ko:K00852 ko00030,map00030 R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TQRC@1239,3F3S5@33958,4HA87@91061,COG0524@1,COG0524@2 NA|NA|NA H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway GHBLAFEN_01167 1423748.BALB01000004_gene555 2.9e-161 574.3 Lactobacillaceae 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSNU@1239,3F3JH@33958,4H9TY@91061,COG1085@1,COG1085@2 NA|NA|NA C Domain of unknown function (DUF4931) GHBLAFEN_01168 405566.lhv_0605 9.3e-234 815.8 Lactobacillaceae ko:K02027,ko:K05813 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 Bacteria 1UNFN@1239,3FBF0@33958,4HCSA@91061,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein GHBLAFEN_01169 1423767.BALU01000019_gene1987 2.7e-60 239.2 Lactobacillaceae Bacteria 1U53C@1239,29NJD@1,309H9@2,3F4BP@33958,4IEUN@91061 NA|NA|NA S Bacteriocin helveticin-J GHBLAFEN_01170 1423754.BALY01000001_gene1682 2.9e-165 587.8 Lactobacillaceae Bacteria 1U7FT@1239,29Q45@1,30B2V@2,3F9JX@33958,4IHBV@91061 NA|NA|NA S SLAP domain GHBLAFEN_01171 1423754.BALY01000001_gene1681 4.5e-130 470.7 Lactobacillaceae ko:K20373,ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria 1UQEK@1239,3F6HP@33958,4IFHS@91061,COG1396@1,COG1396@2 NA|NA|NA K sequence-specific DNA binding GHBLAFEN_01172 525365.HMPREF0548_0610 2.4e-151 541.6 Lactobacillaceae Bacteria 1V6G9@1239,2CJHH@1,32SA1@2,3F5FF@33958,4HIZ6@91061 NA|NA|NA S Protein of unknown function (DUF2974) GHBLAFEN_01173 525365.HMPREF0548_0609 2.2e-106 391.7 Lactobacillaceae glnP GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K02029,ko:K10002,ko:K10040 ko02010,ko02020,map02010,map02020 M00228,M00230,M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.19,3.A.1.3.4 Bacteria 1UJM4@1239,3F3WJ@33958,4HBAS@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease GHBLAFEN_01174 405566.lhv_0600 1.5e-107 395.6 Lactobacillaceae gluC GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K10006,ko:K10040 ko02010,map02010 M00228,M00233 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.9 Bacteria 1TQ5K@1239,3F3XW@33958,4HFBH@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease GHBLAFEN_01175 326425.lhe_0609 4e-150 537.3 Lactobacillaceae glnH ko:K10039 ko02010,map02010 M00228 ko00000,ko00001,ko00002,ko02000 3.A.1.3 Bacteria 1TT11@1239,3F4GG@33958,4HAHV@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter substrate-binding protein GHBLAFEN_01176 405566.lhv_0598 1e-131 476.1 Lactobacillaceae glnQ 3.6.3.21 ko:K02028,ko:K10041 ko02010,map02010 M00228,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein GHBLAFEN_01177 257314.LJ_1095 2.2e-53 218.0 Lactobacillaceae Bacteria 1VTDB@1239,2C77U@1,33S97@2,3FA0U@33958,4HUAC@91061 NA|NA|NA S SIR2-like domain GHBLAFEN_01180 985255.APHJ01000048_gene409 3.3e-10 73.2 Bacteroidetes Bacteria 2DV5Q@1,33U6N@2,4P2AX@976 NA|NA|NA GHBLAFEN_01182 862517.HMPREF9225_0211 1.2e-102 380.9 Bacteria Bacteria COG3344@1,COG3344@2 NA|NA|NA L reverse transcriptase GHBLAFEN_01183 326425.lhe_0430 5.9e-188 663.3 Lactobacillaceae rfbD 1.1.1.133,5.1.3.13 ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777,R06514 RC00182,RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP71@1239,3F4QS@33958,4HBXF@91061,COG1091@1,COG1091@2 NA|NA|NA M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose GHBLAFEN_01184 748671.LCRIS_01734 4.1e-115 420.6 Lactobacillaceae rfbC 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 1TRVB@1239,3F4FN@33958,4HFQB@91061,COG1898@1,COG1898@2 NA|NA|NA M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose GHBLAFEN_01185 326425.lhe_0428 6.9e-164 583.2 Lactobacillaceae rfbA GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0334 Bacteria 1V301@1239,3F4F8@33958,4H9R0@91061,COG1209@1,COG1209@2 NA|NA|NA H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis GHBLAFEN_01186 326425.lhe_0427 8.3e-209 732.6 Lactobacillaceae rfbB 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPWM@1239,3F3R6@33958,4HA3Y@91061,COG1088@1,COG1088@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily GHBLAFEN_01187 326425.lhe_0426 4.3e-222 776.9 Lactobacillaceae Bacteria 1TSDZ@1239,3F5ZT@33958,4ISNQ@91061,COG0500@1,COG0789@1,COG0789@2,COG2226@2 NA|NA|NA KQ helix_turn_helix, mercury resistance GHBLAFEN_01188 257314.LJ_1047 1.3e-133 484.2 Lactobacillaceae Bacteria 1UZCC@1239,3FABV@33958,4IHW1@91061,COG4928@1,COG4928@2 NA|NA|NA S KAP family P-loop domain GHBLAFEN_01189 405566.lhv_1314 3.2e-98 364.4 Lactobacillaceae citX 2.4.2.52,2.7.7.61 ko:K05964,ko:K13927 ko02020,map02020 R09675,R10706 RC00049,RC00063 ko00000,ko00001,ko01000 Bacteria 1VB3E@1239,3F74S@33958,4HMZ5@91061,COG3697@1,COG3697@2 NA|NA|NA HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase GHBLAFEN_01190 1423748.BALB01000013_gene1303 2.8e-52 211.1 Lactobacillaceae arcC 2.7.2.2 ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 R00150,R01395 RC00002,RC00043,RC02803,RC02804 ko00000,ko00001,ko01000 Bacteria 1TP9H@1239,3F3T4@33958,4H9QD@91061,COG0549@1,COG0549@2 NA|NA|NA E Belongs to the carbamate kinase family GHBLAFEN_01191 1423748.BALB01000013_gene1303 1.4e-69 268.9 Lactobacillaceae arcC 2.7.2.2 ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 R00150,R01395 RC00002,RC00043,RC02803,RC02804 ko00000,ko00001,ko01000 Bacteria 1TP9H@1239,3F3T4@33958,4H9QD@91061,COG0549@1,COG0549@2 NA|NA|NA E Belongs to the carbamate kinase family GHBLAFEN_01192 1423748.BALB01000013_gene1302 1.5e-144 518.8 Lactobacillaceae argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.7.2.2 ko:K00611,ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00220,map00230,map00910,map01100,map01110,map01120,map01130,map01200,map01230 M00029,M00844 R00150,R01395,R01398 RC00002,RC00043,RC00096,RC02803,RC02804 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPF2@1239,3F48K@33958,4H9X8@91061,COG0078@1,COG0078@2 NA|NA|NA E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline GHBLAFEN_01193 1033837.WANG_0462 1.1e-12 78.2 Lactobacillaceae argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.7.2.2 ko:K00611,ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00220,map00230,map00910,map01100,map01110,map01120,map01130,map01200,map01230 M00029,M00844 R00150,R01395,R01398 RC00002,RC00043,RC00096,RC02803,RC02804 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPF2@1239,3F48K@33958,4H9X8@91061,COG0078@1,COG0078@2 NA|NA|NA E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline GHBLAFEN_01194 748671.LCRIS_01250 7.1e-90 336.7 Lactobacillaceae arcA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0008218,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0016990,GO:0018101,GO:0018193,GO:0018195,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 R00552 RC00177 ko00000,ko00001,ko01000 Bacteria 1TQWS@1239,3F4VJ@33958,4HCMG@91061,COG2235@1,COG2235@2 NA|NA|NA E Arginine GHBLAFEN_01195 1423748.BALB01000013_gene1301 7.3e-57 226.5 Lactobacillaceae arcA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0008218,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0016990,GO:0018101,GO:0018193,GO:0018195,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 R00552 RC00177 ko00000,ko00001,ko01000 Bacteria 1TQWS@1239,3F4VJ@33958,4HCMG@91061,COG2235@1,COG2235@2 NA|NA|NA E Arginine GHBLAFEN_01196 1423748.BALB01000013_gene1301 3.2e-26 123.6 Lactobacillaceae arcA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0008218,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0016990,GO:0018101,GO:0018193,GO:0018195,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 R00552 RC00177 ko00000,ko00001,ko01000 Bacteria 1TQWS@1239,3F4VJ@33958,4HCMG@91061,COG2235@1,COG2235@2 NA|NA|NA E Arginine GHBLAFEN_01197 405566.lhv_1322 1.8e-156 558.5 Lactobacillaceae lysR5 Bacteria 1UXFR@1239,3F4XG@33958,4HBNZ@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain GHBLAFEN_01198 405566.lhv_1323 0.0 1425.6 Lactobacillaceae 3.6.3.2,3.6.3.6 ko:K01531,ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 3.A.3.3,3.A.3.4 Bacteria 1TPF5@1239,3F55J@33958,4HVA4@91061,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus GHBLAFEN_01199 405566.lhv_1324 2.4e-84 318.2 Lactobacillaceae 3.4.21.96 ko:K01361 ko00000,ko01000,ko01002,ko03110 Bacteria 1U5RD@1239,29NWN@1,309UR@2,3F6D7@33958,4IFFJ@91061 NA|NA|NA S SLAP domain GHBLAFEN_01200 405566.lhv_1325 3e-252 877.5 Lactobacillaceae cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPKY@1239,3F3SF@33958,4H9TI@91061,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol GHBLAFEN_01201 326425.lhe_1257 1.6e-151 542.0 Lactobacillaceae metAA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0008899,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS11970 Bacteria 1TQVR@1239,3F5CA@33958,4H9W4@91061,COG1897@1,COG1897@2 NA|NA|NA E Transfers an acetyl group from acetyl-CoA to GHBLAFEN_01202 405566.lhv_1327 9.8e-169 599.4 Lactobacillaceae cysK GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP30@1239,3F4VD@33958,4HAMU@91061,COG0031@1,COG0031@2 NA|NA|NA E Belongs to the cysteine synthase cystathionine beta- synthase family GHBLAFEN_01203 1423748.BALB01000013_gene1293 1.8e-95 355.1 Lactobacillaceae apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816,ko:K09685 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko03000,ko04147 Bacteria 1V1BV@1239,3F4DB@33958,4HFUA@91061,COG0503@1,COG0503@2 NA|NA|NA F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis GHBLAFEN_01204 326425.lhe_1260 0.0 1503.0 Lactobacillaceae recJ ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPXE@1239,3F42C@33958,4H9UP@91061,COG0608@1,COG0608@2 NA|NA|NA L Single-stranded-DNA-specific exonuclease RecJ GHBLAFEN_01205 326425.lhe_1261 2e-118 431.8 Lactobacillaceae srtA 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 1V83Z@1239,3F54V@33958,4HJV9@91061,COG3764@1,COG3764@2 NA|NA|NA M sortase family GHBLAFEN_01206 1423748.BALB01000013_gene1290 0.0 1206.0 Lactobacillaceae lepA ko:K03596 ko05134,map05134 ko00000,ko00001 Bacteria 1TP0G@1239,3F3Z1@33958,4HASA@91061,COG0481@1,COG0481@2 NA|NA|NA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner GHBLAFEN_01207 891391.LAC30SC_01195 3.8e-15 87.0 Lactobacillaceae Bacteria 1W1MV@1239,28QH1@1,2ZCZ3@2,3F7TZ@33958,4IG80@91061 NA|NA|NA GHBLAFEN_01208 326425.lhe_0817 3.2e-95 354.4 Lactobacillaceae mreD ko:K03571 ko00000,ko03036 9.B.157.1 Bacteria 1U5E6@1239,29NQT@1,309NS@2,3F5PM@33958,4IF5G@91061 NA|NA|NA GHBLAFEN_01209 405566.lhv_0846 1.5e-147 528.9 Lactobacillaceae mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 ko:K03570 ko00000,ko03036 9.B.157.1 Bacteria 1TR1V@1239,3F3MC@33958,4HB0K@91061,COG1792@1,COG1792@2 NA|NA|NA M Involved in formation and maintenance of cell shape GHBLAFEN_01210 326425.lhe_0815 4.2e-173 614.0 Lactobacillaceae mreB ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 1TP51@1239,3F3ZV@33958,4HA4S@91061,COG1077@1,COG1077@2 NA|NA|NA D cell shape determining protein MreB GHBLAFEN_01211 326425.lhe_0814 2.1e-114 418.3 Lactobacillaceae radC ko:K03630 ko00000 Bacteria 1TQ3K@1239,3F5IM@33958,4HB1W@91061,COG2003@1,COG2003@2 NA|NA|NA L DNA repair protein GHBLAFEN_01212 326425.lhe_0813 1.3e-125 455.7 Lactobacillaceae Bacteria 1V1N8@1239,3F56K@33958,4HG58@91061,COG0637@1,COG0637@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase GHBLAFEN_01213 405566.lhv_0842 3e-237 827.4 Lactobacillaceae folC 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0166 Bacteria 1TPX5@1239,3F498@33958,4HBJM@91061,COG0285@1,COG0285@2 NA|NA|NA H Belongs to the folylpolyglutamate synthase family GHBLAFEN_01214 405566.lhv_0841 0.0 1823.1 Lactobacillaceae valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iLJ478.TM1817 Bacteria 1TPN4@1239,3F3RB@33958,4HB85@91061,COG0525@1,COG0525@2 NA|NA|NA J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner GHBLAFEN_01215 1033837.WANG_0855 1.4e-96 359.0 Lactobacillaceae ko:K19167 ko00000,ko02048 Bacteria 1TU7K@1239,2BT6P@1,32NBV@2,3FARS@33958,4II8D@91061 NA|NA|NA GHBLAFEN_01216 1033837.WANG_0856 9.5e-92 342.8 Lactobacillaceae Bacteria 1UZCF@1239,3F48H@33958,4HDPY@91061,COG4485@1,COG4485@2 NA|NA|NA S Bacterial membrane protein, YfhO GHBLAFEN_01217 1033837.WANG_0856 8.7e-120 436.4 Lactobacillaceae Bacteria 1UZCF@1239,3F48H@33958,4HDPY@91061,COG4485@1,COG4485@2 NA|NA|NA S Bacterial membrane protein, YfhO GHBLAFEN_01218 1033837.WANG_0300 1.1e-12 78.6 Lactobacillaceae Bacteria 1UZCF@1239,3F48H@33958,4HDPY@91061,COG4485@1,COG4485@2 NA|NA|NA S Bacterial membrane protein, YfhO GHBLAFEN_01219 1033837.WANG_0857 8.9e-170 602.8 Lactobacillaceae yfdH ko:K12999,ko:K20534 ko00000,ko01000,ko01003,ko01005,ko02000 4.D.2.1.9 GT2 Bacteria 1TPR3@1239,3FBT4@33958,4HC2Z@91061,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase like family 2 GHBLAFEN_01220 1033837.WANG_0858 2.4e-66 258.1 Lactobacillaceae 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003 GT2 Bacteria 1VP71@1239,3F73E@33958,4HSE0@91061,COG2246@1,COG2246@2 NA|NA|NA S GtrA-like protein GHBLAFEN_01221 1033837.WANG_0859 6.9e-214 749.6 Lactobacillaceae 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1V3Z1@1239,3F555@33958,4IEZK@91061,COG0584@1,COG0584@2 NA|NA|NA C Glycerophosphoryl diester phosphodiesterase family GHBLAFEN_01222 1033837.WANG_0860 6.7e-23 112.5 Lactobacillaceae Bacteria 1U7X0@1239,2BN97@1,32GWQ@2,3FA9Y@33958,4IHUC@91061 NA|NA|NA GHBLAFEN_01223 748671.LCRIS_01392 3.3e-19 101.7 Lactobacillaceae Bacteria 1U8EG@1239,2DIDE@1,302VY@2,3FAW7@33958,4IICB@91061 NA|NA|NA S SLAP domain GHBLAFEN_01225 1423748.BALB01000001_gene60 0.0 1216.4 Lactobacillaceae 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAR@1239,3F53U@33958,4HAXN@91061,COG1053@1,COG1053@2,COG3976@1,COG3976@2 NA|NA|NA C FAD binding domain GHBLAFEN_01226 405566.lhv_1029 3.2e-10 70.1 Lactobacillaceae dedA 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 1V2XQ@1239,3FBF1@33958,4IPZ1@91061,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein GHBLAFEN_01227 1423748.BALB01000010_gene1118 4.2e-75 287.3 Lactobacillaceae dedA 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 1V2XQ@1239,3FBF1@33958,4IPZ1@91061,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein GHBLAFEN_01228 405566.lhv_1028 1.4e-248 865.1 Lactobacillaceae yfnA ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3F3QY@33958,4HA66@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid GHBLAFEN_01229 1423748.BALB01000010_gene1116 3.3e-43 180.6 Lactobacillaceae gyaR 1.1.1.26,2.7.1.165 ko:K00015,ko:K11529,ko:K15893 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346,M00532 R00717,R01388,R08572 RC00002,RC00031,RC00042,RC00428 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCX@1239,3F4Z6@33958,4HASY@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family GHBLAFEN_01230 525365.HMPREF0548_0990 1.4e-79 302.4 Lactobacillaceae gyaR 1.1.1.26,2.7.1.165 ko:K00015,ko:K11529,ko:K15893 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346,M00532 R00717,R01388,R08572 RC00002,RC00031,RC00042,RC00428 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCX@1239,3FB6D@33958,4HUAD@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family GHBLAFEN_01231 1423748.BALB01000010_gene1115 3.5e-14 83.2 Lactobacillaceae gyaR 1.1.1.26,2.7.1.165 ko:K00015,ko:K11529,ko:K15893 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346,M00532 R00717,R01388,R08572 RC00002,RC00031,RC00042,RC00428 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCX@1239,3F4Z6@33958,4HASY@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family GHBLAFEN_01232 1423748.BALB01000010_gene1114 2.3e-10 70.1 Lactobacillaceae yxeH Bacteria 1TR16@1239,3F55S@33958,4HCZ6@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase GHBLAFEN_01233 1423748.BALB01000010_gene1114 3.1e-27 127.1 Lactobacillaceae yxeH Bacteria 1TR16@1239,3F55S@33958,4HCZ6@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase GHBLAFEN_01234 1423748.BALB01000010_gene1114 3.4e-86 324.3 Lactobacillaceae yxeH Bacteria 1TR16@1239,3F55S@33958,4HCZ6@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase GHBLAFEN_01235 405566.lhv_1020 2.5e-74 284.6 Lactobacillaceae Bacteria 1TPM1@1239,3FB4S@33958,4HAG6@91061,COG0656@1,COG0656@2 NA|NA|NA S reductase GHBLAFEN_01236 326425.lhe_0941 1.7e-34 151.8 Lactobacillaceae Bacteria 1TPM1@1239,3FB4S@33958,4HAG6@91061,COG0656@1,COG0656@2 NA|NA|NA S reductase GHBLAFEN_01237 405566.lhv_1017 2.7e-219 767.7 Lactobacillaceae coaBC 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPP3@1239,3F3XX@33958,4HAK8@91061,COG0452@1,COG0452@2 NA|NA|NA H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine GHBLAFEN_01238 405566.lhv_1015 3.4e-222 777.3 Lactobacillaceae patA 2.6.1.1 ko:K00812,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00525 R00355,R00694,R00734,R00896,R02433,R02619,R04467,R05052 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase GHBLAFEN_01239 405566.lhv_1014 0.0 1251.1 Lactobacillaceae aspS 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPCN@1239,3F4PE@33958,4HACD@91061,COG0173@1,COG0173@2 NA|NA|NA J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) GHBLAFEN_01240 326425.lhe_0937 8.9e-245 852.4 Lactobacillaceae hisS 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP3D@1239,3F3M3@33958,4HAM2@91061,COG0124@1,COG0124@2 NA|NA|NA J histidyl-tRNA synthetase GHBLAFEN_01241 405566.lhv_1012 1.1e-74 285.8 Lactobacillaceae dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K07560 ko00000,ko01000,ko03016 Bacteria 1V6GH@1239,3F6GK@33958,4HINN@91061,COG1490@1,COG1490@2 NA|NA|NA J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality GHBLAFEN_01242 326425.lhe_0935 0.0 1470.7 Lactobacillaceae relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 iHN637.CLJU_RS16615,iYO844.BSU27600 Bacteria 1TNYZ@1239,3F44F@33958,4HBX7@91061,COG0317@1,COG0317@2 NA|NA|NA KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance GHBLAFEN_01243 326425.lhe_0934 8.5e-60 236.1 Lactobacillaceae Bacteria 1U6F0@1239,29PCU@1,30AB2@2,3F7RV@33958,4IG6U@91061 NA|NA|NA GHBLAFEN_01244 405566.lhv_1009 1.2e-174 619.0 Lactobacillaceae prmA ko:K02687 ko00000,ko01000,ko03009 Bacteria 1TPKI@1239,3F47Z@33958,4HAMF@91061,COG2264@1,COG2264@2 NA|NA|NA J Ribosomal protein L11 methyltransferase GHBLAFEN_01245 326425.lhe_0932 2.8e-85 321.2 Lactobacillaceae ybaK ko:K03976 ko00000,ko01000,ko03016 Bacteria 1V6JF@1239,3F5H1@33958,4HHVB@91061,COG2606@1,COG2606@2 NA|NA|NA S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily GHBLAFEN_01246 326425.lhe_1898 2.1e-117 428.3 Lactobacillaceae ko:K07052 ko00000 Bacteria 1VFRX@1239,3F4Q0@33958,4HRQQ@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity GHBLAFEN_01247 405566.lhv_2072 1.9e-195 688.3 Lactobacillaceae Bacteria 1V8H4@1239,3FC81@33958,4HI4B@91061,COG1434@1,COG1434@2 NA|NA|NA S DUF218 domain GHBLAFEN_01248 1423748.BALB01000021_gene1667 0.0 1438.3 Lactobacillaceae macB_3 ko:K02003,ko:K02004,ko:K05685 ko02010,map02010 M00258,M00709 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 Bacteria 1TPBJ@1239,3F44P@33958,4HBK7@91061,COG0577@1,COG0577@2,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein GHBLAFEN_01249 1423748.BALB01000021_gene1666 2.9e-97 361.3 Lactobacillaceae Bacteria 1V2ZW@1239,3FBM9@33958,4IR4I@91061,COG4684@1,COG4684@2 NA|NA|NA S ECF transporter, substrate-specific component GHBLAFEN_01250 326425.lhe_1902 2.2e-159 568.2 Lactobacillaceae yeaE Bacteria 1TPM1@1239,3FB4R@33958,4HU74@91061,COG0656@1,COG0656@2 NA|NA|NA S Aldo/keto reductase family GHBLAFEN_01251 405566.lhv_2077 3.9e-133 480.7 Lactobacillaceae nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0008150,GO:0008152,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135 3.1.1.31,3.5.99.6 ko:K01057,ko:K02564 ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R00765,R02035 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP10@1239,3F3NR@33958,4HAG4@91061,COG0363@1,COG0363@2 NA|NA|NA G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion GHBLAFEN_01252 748671.LCRIS_01642 1.4e-100 372.9 Lactobacillaceae ybbH_2 ko:K03481 ko00000,ko03000 Bacteria 1TR0N@1239,3F42G@33958,4HB9E@91061,COG1737@1,COG1737@2 NA|NA|NA K rpiR family GHBLAFEN_01253 748671.LCRIS_01643 8.5e-145 520.0 Lactobacillaceae ko:K09963 ko00000 Bacteria 1TRIY@1239,3FB4D@33958,4HAHJ@91061,COG3589@1,COG3589@2 NA|NA|NA S Bacterial protein of unknown function (DUF871) GHBLAFEN_01254 945021.TEH_24400 4.3e-190 671.4 Enterococcaceae yfeW GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008658,GO:0009002,GO:0016020,GO:0016787,GO:0017171,GO:0019538,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0140096,GO:1901363,GO:1901564,GO:1901681 3.4.16.4 ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1U828@1239,4B6QZ@81852,4HA0Q@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase GHBLAFEN_01255 1033837.WANG_1180 4.3e-121 441.0 Lactobacillaceae murQ 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 R08555 RC00397,RC00746 ko00000,ko00001,ko01000 Bacteria 1TPSF@1239,3F4T1@33958,4HBWP@91061,COG2103@1,COG2103@2 NA|NA|NA G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate GHBLAFEN_01256 748671.LCRIS_01645 0.0 1100.9 Lactobacillaceae sacX GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090588 2.7.1.208,2.7.1.211 ko:K02749,ko:K02750,ko:K02755,ko:K02756,ko:K02757,ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00268,M00269,M00271 R00811,R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.10,4.A.1.1.16,4.A.1.1.4,4.A.1.1.8,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system GHBLAFEN_01258 405566.lhv_2079 1e-116 426.0 Lactobacillaceae dak 2.7.1.74,2.7.1.76 ko:K00893,ko:K10353 ko00230,ko00240,ko01100,map00230,map00240,map01100 R00185,R01666,R02089 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TPJ1@1239,3F488@33958,4HA9N@91061,COG1428@1,COG1428@2 NA|NA|NA F deoxynucleoside kinase GHBLAFEN_01259 1423748.BALB01000021_gene1662 1.8e-127 461.8 Lactobacillaceae dgk 2.7.1.74,2.7.1.76 ko:K00893,ko:K10353 ko00230,ko00240,ko01100,map00230,map00240,map01100 R00185,R01666,R02089 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TPJ1@1239,3F488@33958,4HA9N@91061,COG1428@1,COG1428@2 NA|NA|NA F deoxynucleoside kinase GHBLAFEN_01260 525365.HMPREF0548_1647 8.5e-43 179.9 Lactobacillaceae Bacteria 1TSH6@1239,3F5HS@33958,4HEX8@91061,COG3385@1,COG3385@2 NA|NA|NA L PFAM transposase, IS4 family protein GHBLAFEN_01261 1423748.BALB01000003_gene481 0.0 1294.6 Lactobacillaceae XK27_00340 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPV2@1239,3F4S2@33958,4HB9S@91061,COG0737@1,COG0737@2 NA|NA|NA F Belongs to the 5'-nucleotidase family GHBLAFEN_01262 326425.lhe_1067 0.0 1291.9 Lactobacillaceae pepO 3.4.24.71 ko:K01415,ko:K07386 ko00000,ko01000,ko01002,ko04147 Bacteria 1TQTA@1239,3F4CX@33958,4HDSF@91061,COG3590@1,COG3590@2 NA|NA|NA O Peptidase family M13 GHBLAFEN_01263 353496.LBU_0205 3.3e-59 234.2 Lactobacillaceae pdxH ko:K07006 ko00000 Bacteria 1VW4G@1239,3F6IW@33958,4HW37@91061,COG3576@1,COG3576@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase GHBLAFEN_01264 326425.lhe_1069 5.7e-95 353.6 Lactobacillaceae steT GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ48@1239,3F3YJ@33958,4HBGT@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid GHBLAFEN_01265 326425.lhe_1069 6.5e-106 390.2 Lactobacillaceae steT GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ48@1239,3F3YJ@33958,4HBGT@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid GHBLAFEN_01266 405566.lhv_1171 5.7e-230 803.1 Lactobacillaceae amd 3.5.1.47 ko:K01436,ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPD7@1239,3FC42@33958,4H9WQ@91061,COG1473@1,COG1473@2 NA|NA|NA E Peptidase family M20/M25/M40 GHBLAFEN_01267 405566.lhv_1172 1.6e-185 655.2 Lactobacillaceae mmuM GO:0003674,GO:0003824,GO:0005488,GO:0006575,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008270,GO:0008757,GO:0008898,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033477,GO:0033554,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:1901564 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHQ5@1239,3F4UT@33958,4HAS6@91061,COG2040@1,COG2040@2 NA|NA|NA H homocysteine S-methyltransferase GHBLAFEN_01268 525365.HMPREF0548_1074 9.7e-229 799.3 Lactobacillaceae mmuP GO:0000096,GO:0000097,GO:0000100,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0015806,GO:0016020,GO:0016053,GO:0019752,GO:0022857,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682 ko:K02205,ko:K03293,ko:K16235,ko:K16236 ko00000,ko02000 2.A.3.1,2.A.3.1.10 Bacteria 1UHNR@1239,3F4BG@33958,4HUT7@91061,COG0833@1,COG0833@2 NA|NA|NA E amino acid GHBLAFEN_01269 353496.LBU_0210 3.4e-241 840.5 Lactobacillaceae ko:K09384 ko00000 Bacteria 1TPQU@1239,3F47M@33958,4HBI0@91061,COG3410@1,COG3410@2 NA|NA|NA N Uncharacterized conserved protein (DUF2075) GHBLAFEN_01270 97137.C821_00801 1.4e-27 128.3 Lactobacillaceae merA GO:0000302,GO:0000305,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0019725,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901530,GO:1901700,GO:1990748 1.16.1.1,1.8.1.7 ko:K00383,ko:K00520,ko:K21739 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1TP1W@1239,3FC6T@33958,4HBZF@91061,COG1249@1,COG1249@2 NA|NA|NA C Pyridine nucleotide-disulfide oxidoreductase GHBLAFEN_01271 748671.LCRIS_01259 1.3e-53 216.1 Lactobacillaceae merA GO:0000302,GO:0000305,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0019725,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901530,GO:1901700,GO:1990748 1.16.1.1,1.8.1.7 ko:K00383,ko:K00520,ko:K21739 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1TP1W@1239,3FC6T@33958,4HBZF@91061,COG1249@1,COG1249@2 NA|NA|NA C Pyridine nucleotide-disulfide oxidoreductase GHBLAFEN_01272 1033837.WANG_0579 2.2e-68 265.0 Lactobacillaceae merA GO:0000302,GO:0000305,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0019725,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901530,GO:1901700,GO:1990748 1.16.1.1,1.8.1.7 ko:K00383,ko:K00520,ko:K21739 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1TP1W@1239,3FC6T@33958,4HBZF@91061,COG1249@1,COG1249@2 NA|NA|NA C Pyridine nucleotide-disulfide oxidoreductase GHBLAFEN_01273 1423748.BALB01000033_gene1964 2.2e-207 728.4 Lactobacillaceae Bacteria 1U5CG@1239,29V6Q@1,309MR@2,3F5IP@33958,4IF3N@91061 NA|NA|NA GHBLAFEN_01274 525365.HMPREF0548_1117 7.1e-257 892.9 Lactobacillaceae Bacteria 1TQJ0@1239,3F4C3@33958,4H9P7@91061,COG1288@1,COG1288@2 NA|NA|NA S C4-dicarboxylate anaerobic carrier GHBLAFEN_01275 405566.lhv_1180 7.4e-92 343.2 Lactobacillaceae hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 Bacteria 1V1C9@1239,3F3K3@33958,4HFZ2@91061,COG0634@1,COG0634@2 NA|NA|NA F Belongs to the purine pyrimidine phosphoribosyltransferase family GHBLAFEN_01276 1423748.BALB01000020_gene1596 1.8e-23 114.8 Lactobacillaceae Bacteria 1U6M0@1239,29PHT@1,30AFY@2,3F84R@33958,4IGDT@91061 NA|NA|NA GHBLAFEN_01277 326425.lhe_1077 4.7e-102 377.1 Lactobacillaceae ko:K07038 ko00000 Bacteria 1TV5H@1239,3F689@33958,4ICPV@91061,COG1988@1,COG1988@2 NA|NA|NA S LexA-binding, inner membrane-associated putative hydrolase GHBLAFEN_01278 1423748.BALB01000033_gene1959 3e-37 160.6 Lactobacillaceae Bacteria 1U6BF@1239,29PA0@1,30A85@2,3F7IE@33958,4IG31@91061 NA|NA|NA GHBLAFEN_01279 525365.HMPREF0548_1061 2.1e-121 441.8 Lactobacillaceae malY 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 Bacteria 1TP5G@1239,3F4JX@33958,4H9PE@91061,COG1168@1,COG1168@2 NA|NA|NA E Aminotransferase, class I GHBLAFEN_01280 1423748.BALB01000033_gene1956 1.2e-37 162.2 Lactobacillaceae malY 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 Bacteria 1TP5G@1239,3F4JX@33958,4H9PE@91061,COG1168@1,COG1168@2 NA|NA|NA E Aminotransferase, class I GHBLAFEN_01281 326425.lhe_1080 2.6e-55 221.1 Lactobacillaceae Bacteria 1U7WD@1239,2BN3Q@1,32GQJ@2,3FA99@33958,4IHTS@91061 NA|NA|NA GHBLAFEN_01282 405566.lhv_1189 6.4e-241 839.7 Lactobacillaceae brnQ GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 ko:K03311 ko00000 2.A.26 Bacteria 1TQIS@1239,3F3KC@33958,4HAKA@91061,COG1114@1,COG1114@2 NA|NA|NA U Component of the transport system for branched-chain amino acids GHBLAFEN_01283 936140.AEOT01000026_gene815 2e-68 265.4 Lactobacillaceae ko:K07150 ko00000 Bacteria 1TQWV@1239,3F48N@33958,4HEYY@91061,COG1811@1,COG1811@2 NA|NA|NA S Protein of unknown function (DUF554) GHBLAFEN_01284 1140001.I571_01003 1.2e-13 81.6 Enterococcaceae ko:K07150 ko00000 Bacteria 1TQWV@1239,4AZQN@81852,4HEYY@91061,COG1811@1,COG1811@2 NA|NA|NA S Protein of unknown function (DUF554) GHBLAFEN_01285 1260356.D920_01766 4.5e-45 188.3 Enterococcaceae ko:K09681 ko00000,ko03000 Bacteria 1TQ6Y@1239,4B1U4@81852,4HB94@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain GHBLAFEN_01286 936140.AEOT01000026_gene811 1.6e-242 845.1 Lactobacillaceae ubiX GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129,4.1.1.98 ko:K03182,ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ6V@1239,3F50J@33958,4HM1D@91061,COG0043@1,COG0043@2,COG0163@1,COG0163@2 NA|NA|NA H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase GHBLAFEN_01287 1158601.I585_02393 5.3e-28 130.6 Enterococcaceae ubiX GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3JV@1239,4B0F1@81852,4HFZX@91061,COG0163@1,COG0163@2 NA|NA|NA H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN GHBLAFEN_01288 1423724.BAMM01000002_gene398 6.5e-22 110.5 Lactobacillaceae Bacteria 1VX0V@1239,2F603@1,33YIJ@2,3F6YU@33958,4HXF9@91061 NA|NA|NA GHBLAFEN_01289 1423748.BALB01000033_gene1951 3.7e-82 310.8 Lactobacillaceae tdh 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPWP@1239,3F3WG@33958,4HABC@91061,COG1063@1,COG1063@2 NA|NA|NA C Zinc-binding dehydrogenase GHBLAFEN_01290 1423748.BALB01000033_gene1951 2.2e-85 321.6 Lactobacillaceae tdh 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPWP@1239,3F3WG@33958,4HABC@91061,COG1063@1,COG1063@2 NA|NA|NA C Zinc-binding dehydrogenase GHBLAFEN_01292 1423758.BN55_03690 3.8e-68 264.2 Lactobacillaceae glcD2 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 R00475 RC00042 ko00000,ko00001,ko01000 Bacteria 1TPBC@1239,3F4AD@33958,4H9UU@91061,COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidases, C-terminal domain GHBLAFEN_01293 1423748.BALB01000033_gene1947 3e-68 264.6 Lactobacillaceae glcD2 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 R00475 RC00042 ko00000,ko00001,ko01000 Bacteria 1TPBC@1239,3F4AD@33958,4H9UU@91061,COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidases, C-terminal domain GHBLAFEN_01294 748671.LCRIS_01831 2.5e-58 231.5 Lactobacillaceae glcD2 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 R00475 RC00042 ko00000,ko00001,ko01000 Bacteria 1TPBC@1239,3F4AD@33958,4H9UU@91061,COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidases, C-terminal domain GHBLAFEN_01295 326425.lhe_1082 1.1e-272 945.3 Lactobacillaceae pepV 3.5.1.18 ko:K01270,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 M00016 R00899,R02734,R04951 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPEG@1239,3F3UV@33958,4HC14@91061,COG0624@1,COG0624@2 NA|NA|NA E dipeptidase PepV GHBLAFEN_01296 326425.lhe_1083 5.3e-189 666.8 Lactobacillaceae Bacteria 1V4BS@1239,3F3QN@33958,4HJRT@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase GHBLAFEN_01297 405566.lhv_1193 0.0 1749.6 Lactobacillaceae ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 iJN678.ppc,iSFV_1184.SFV_4025 Bacteria 1TQB6@1239,3F4BB@33958,4HCAF@91061,COG2352@1,COG2352@2 NA|NA|NA H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle GHBLAFEN_01298 405566.lhv_1195 9.6e-47 192.6 Lactobacillaceae Bacteria 1VQ4B@1239,2A8RI@1,30XU8@2,3F4H8@33958,4IJHJ@91061 NA|NA|NA GHBLAFEN_01299 405566.lhv_1195 7.4e-138 496.5 Lactobacillaceae Bacteria 1VQ4B@1239,2A8RI@1,30XU8@2,3F4H8@33958,4IJHJ@91061 NA|NA|NA GHBLAFEN_01300 405566.lhv_1196 4.6e-88 330.5 Lactobacillaceae XK27_09675 ko:K07105 ko00000 Bacteria 1UHPQ@1239,3FBT6@33958,4IS5I@91061,COG0454@1,COG0454@2 NA|NA|NA K Acetyltransferase (GNAT) domain GHBLAFEN_01301 326425.lhe_1089 3e-53 214.5 Lactobacillaceae Bacteria 1U62T@1239,29P3F@1,30A1N@2,3F6WA@33958,4IFRY@91061 NA|NA|NA S Protein of unknown function (DUF3021) GHBLAFEN_01302 326425.lhe_1090 1.6e-76 292.0 Lactobacillaceae Bacteria 1U5WZ@1239,3F6MT@33958,4IFKG@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain GHBLAFEN_01303 326425.lhe_1091 1e-41 175.6 Lactobacillaceae Bacteria 1U75H@1239,29PX4@1,30AVF@2,3F907@33958,4IH06@91061 NA|NA|NA GHBLAFEN_01304 326425.lhe_1092 8e-125 453.0 Lactobacillaceae magIII ko:K07457 ko00000 Bacteria 1V4SG@1239,3F62T@33958,4HI5U@91061,COG2231@1,COG2231@2 NA|NA|NA L Base excision DNA repair protein, HhH-GPD family GHBLAFEN_01305 1423748.BALB01000017_gene1464 2e-22 110.9 Lactobacillaceae ko:K07729 ko00000,ko03000 Bacteria 1TVR2@1239,3F8EN@33958,4I3W8@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins GHBLAFEN_01306 1423748.BALB01000017_gene1465 2.4e-51 208.4 Lactobacillaceae Bacteria 1U73G@1239,2AG2Z@1,3167E@2,3F8XJ@33958,4IGY2@91061 NA|NA|NA GHBLAFEN_01307 1033837.WANG_0623 8.9e-140 503.1 Lactobacillaceae glxR 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 iJN678.mmsB Bacteria 1TR4F@1239,3F3XC@33958,4H9MA@91061,COG2084@1,COG2084@2 NA|NA|NA I Dehydrogenase GHBLAFEN_01308 1423748.BALB01000017_gene1468 7.4e-228 796.2 Lactobacillaceae yrvN ko:K07478 ko00000 Bacteria 1TPVV@1239,3F44J@33958,4HAIS@91061,COG2256@1,COG2256@2 NA|NA|NA L AAA C-terminal domain GHBLAFEN_01309 1423748.BALB01000017_gene1469 2.1e-32 144.4 Lactobacillaceae Bacteria 1W48A@1239,2DTY5@1,33N6A@2,3F7WG@33958,4I01I@91061 NA|NA|NA GHBLAFEN_01310 936140.AEOT01000002_gene2158 9.1e-71 273.9 Lactobacillaceae fabK 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPC3@1239,3F4PC@33958,4H9T0@91061,COG2070@1,COG2070@2 NA|NA|NA S Nitronate monooxygenase GHBLAFEN_01311 525365.HMPREF0548_1222 1.5e-84 318.9 Lactobacillaceae kptA ko:K07559 ko00000,ko01000,ko03016 Bacteria 1V49Y@1239,3F5JJ@33958,4HN5V@91061,COG1859@1,COG1859@2 NA|NA|NA H Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase GHBLAFEN_01312 525365.HMPREF0548_1157 8.5e-66 257.3 Lactobacillaceae Bacteria 1UPRG@1239,2BSQ8@1,32MT2@2,3F7BK@33958,4IV9J@91061 NA|NA|NA S Abi-like protein GHBLAFEN_01314 257314.LJ_1161 1e-125 456.4 Lactobacillaceae 4.1.1.45 ko:K03392,ko:K07045 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 Bacteria 1TRAY@1239,3F485@33958,4HFH2@91061,COG2159@1,COG2159@2 NA|NA|NA S Amidohydrolase GHBLAFEN_01315 1033837.WANG_1278 3e-94 351.3 Lactobacillaceae lacA 2.3.1.79 ko:K00661 ko00000,ko01000 Bacteria 1V56K@1239,3F54I@33958,4HTPS@91061,COG0110@1,COG0110@2 NA|NA|NA S Maltose acetyltransferase GHBLAFEN_01316 1033837.WANG_1277 2.6e-109 401.4 Lactobacillaceae Bacteria 1VVR5@1239,3F5NS@33958,4HWFJ@91061,COG1359@1,COG1359@2 NA|NA|NA G Antibiotic biosynthesis monooxygenase GHBLAFEN_01317 1033837.WANG_1276 2.8e-27 127.1 Lactobacillaceae Bacteria 1VBEN@1239,3F75W@33958,4HM8H@91061,COG4334@1,COG4334@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2255) GHBLAFEN_01318 1033837.WANG_1275 1e-69 269.2 Lactobacillaceae adhR Bacteria 1VAAP@1239,3F6JI@33958,4HKZ9@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance GHBLAFEN_01319 1033837.WANG_1274 6e-112 410.2 Lactobacillaceae papP ko:K02029 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TRU3@1239,3F3XD@33958,4HGE1@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter, permease protein GHBLAFEN_01320 1033837.WANG_1273 2e-86 325.5 Lactobacillaceae ko:K02029,ko:K10040 ko02010,map02010 M00228,M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3 Bacteria 1TR7R@1239,3F45E@33958,4HGVA@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease GHBLAFEN_01321 326425.lhe_1104 5.3e-133 480.3 Lactobacillaceae glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,3FC3P@33958,4HDK7@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein GHBLAFEN_01322 326425.lhe_1105 1.7e-159 568.5 Lactobacillaceae cjaA ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TT11@1239,3F54P@33958,4HFBQ@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter substrate-binding protein GHBLAFEN_01323 525365.HMPREF0548_1650 4.7e-123 447.2 Lactobacillaceae ko:K07483 ko00000 Bacteria 1V1QC@1239,3F5BG@33958,4HH7E@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain GHBLAFEN_01324 1423754.BALY01000006_gene1368 5e-66 256.9 Lactobacillaceae Bacteria 1TQEG@1239,3F43M@33958,4HD6M@91061,COG2801@1,COG2801@2 NA|NA|NA L hmm pf00665 GHBLAFEN_01325 1423754.BALY01000006_gene1368 1e-122 446.0 Lactobacillaceae Bacteria 1TQEG@1239,3F43M@33958,4HD6M@91061,COG2801@1,COG2801@2 NA|NA|NA L hmm pf00665 GHBLAFEN_01327 326425.lhe_1108 9.9e-117 426.0 Lactobacillaceae ko:K04763 ko00000,ko03036 Bacteria 1V2RX@1239,3F4SP@33958,4IEJ7@91061,COG0582@1,COG0582@2 NA|NA|NA L Integrase GHBLAFEN_01329 326425.lhe_1109 2e-255 887.9 Lactobacillaceae gor 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1TS0Z@1239,3F3K2@33958,4HBYB@91061,COG1249@1,COG1249@2 NA|NA|NA C Glutathione reductase GHBLAFEN_01330 326425.lhe_1110 6.2e-53 213.4 Lactobacillaceae Bacteria 1V6Z8@1239,3F6WQ@33958,4HMP7@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) family GHBLAFEN_01331 1033837.WANG_1266 6.8e-58 229.9 Lactobacillaceae Bacteria 1VSYU@1239,3F4J2@33958,4HU15@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha beta hydrolase GHBLAFEN_01332 575594.ACOH01000002_gene1160 2.9e-33 148.3 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TPW7@1239,3F5IC@33958,4HEFQ@91061,COG1073@1,COG1073@2 NA|NA|NA S Hydrolases of the alpha beta superfamily GHBLAFEN_01333 1423814.HMPREF0549_0425 2.1e-39 168.3 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TPW7@1239,3F5IC@33958,4HEFQ@91061,COG1073@1,COG1073@2 NA|NA|NA S Hydrolases of the alpha beta superfamily GHBLAFEN_01334 326425.lhe_1112 9.9e-143 512.7 Lactobacillaceae nfrA 1.5.1.38,1.5.1.39 ko:K19285,ko:K19286 ko00740,ko01100,map00740,map01100 R05705,R05706 RC00126 ko00000,ko00001,ko01000 Bacteria 1UB8S@1239,3F4IY@33958,4HEGP@91061,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase GHBLAFEN_01335 326425.lhe_1113 5.4e-47 193.4 Bacteria 1.1.1.3 ko:K00003,ko:K07166 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria COG3830@1,COG3830@2 NA|NA|NA T phosphoserine phosphatase activity GHBLAFEN_01336 326425.lhe_1114 1.9e-83 315.1 Lactobacillaceae Bacteria 1V6JC@1239,3F58C@33958,4IF0F@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family GHBLAFEN_01337 405566.lhv_1224 6.1e-88 330.1 Lactobacillaceae ko:K09705,ko:K12410 ko00000,ko01000 Bacteria 1V192@1239,3F5GG@33958,4IJ3S@91061,COG0846@1,COG0846@2 NA|NA|NA K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form GHBLAFEN_01338 525365.HMPREF0548_1143 1.5e-39 168.7 Lactobacillaceae Bacteria 1V192@1239,3F5GG@33958,4IJ3S@91061,COG0846@1,COG0846@2 NA|NA|NA K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form GHBLAFEN_01339 525365.HMPREF0548_1143 4.8e-50 203.8 Lactobacillaceae Bacteria 1V192@1239,3F5GG@33958,4IJ3S@91061,COG0846@1,COG0846@2 NA|NA|NA K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form GHBLAFEN_01340 405566.lhv_1226 1.5e-163 582.0 Lactobacillaceae ko:K12410 ko00000,ko01000 Bacteria 1TQB7@1239,3F4Q7@33958,4HAQT@91061,COG0846@1,COG0846@2 NA|NA|NA K COG COG0846 NAD-dependent protein deacetylases, SIR2 family GHBLAFEN_01341 326425.lhe_1117 4.4e-94 350.5 Lactobacillaceae Bacteria 1V5SA@1239,3FBU8@33958,4ISZX@91061,COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase GHBLAFEN_01342 326425.lhe_1118 5.8e-85 320.1 Lactobacillaceae dps ko:K04047 ko00000,ko03036 Bacteria 1VCVJ@1239,3F5WI@33958,4HMBD@91061,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family GHBLAFEN_01343 525365.HMPREF0548_1229 4.2e-41 174.5 Lactobacillaceae Bacteria 1U67D@1239,29P6U@1,30A4Y@2,3F78T@33958,4IFXW@91061 NA|NA|NA GHBLAFEN_01344 1423748.BALB01000017_gene1504 7.8e-32 142.9 Lactobacillaceae Bacteria 1U6QB@1239,29PK4@1,30AI9@2,3F8AM@33958,4IGHF@91061 NA|NA|NA GHBLAFEN_01345 1423748.BALB01000017_gene1505 7.1e-18 95.5 Lactobacillaceae snf 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 1TPFZ@1239,3F52K@33958,4HAIF@91061,COG0553@1,COG0553@2 NA|NA|NA KL domain protein GHBLAFEN_01346 1423748.BALB01000017_gene1505 3.9e-43 180.6 Lactobacillaceae snf 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 1TPFZ@1239,3F52K@33958,4HAIF@91061,COG0553@1,COG0553@2 NA|NA|NA KL domain protein GHBLAFEN_01347 1423748.BALB01000017_gene1505 1.8e-288 998.0 Lactobacillaceae snf 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 1TPFZ@1239,3F52K@33958,4HAIF@91061,COG0553@1,COG0553@2 NA|NA|NA KL domain protein GHBLAFEN_01348 1423748.BALB01000017_gene1505 1.4e-102 379.0 Lactobacillaceae snf 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 1TPFZ@1239,3F52K@33958,4HAIF@91061,COG0553@1,COG0553@2 NA|NA|NA KL domain protein GHBLAFEN_01349 405566.lhv_1231 1.5e-107 395.6 Lactobacillaceae plsY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15,3.5.1.104 ko:K08591,ko:K22278 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1VA3J@1239,3F543@33958,4HC55@91061,COG0344@1,COG0344@2 NA|NA|NA I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP GHBLAFEN_01350 405566.lhv_1232 0.0 1213.0 Lactobacillaceae parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470,ko:K02622 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TQCF@1239,3F430@33958,4H9UC@91061,COG0187@1,COG0187@2 NA|NA|NA L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule GHBLAFEN_01351 405566.lhv_1233 0.0 1585.5 Lactobacillaceae parC GO:0005575,GO:0005622,GO:0005623,GO:0009330,GO:0032991,GO:0044424,GO:0044464 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TRE7@1239,3F3MJ@33958,4HAQB@91061,COG0188@1,COG0188@2 NA|NA|NA L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule GHBLAFEN_01352 326425.lhe_1123 3.2e-170 604.4 Lactobacillaceae Bacteria 1UYS5@1239,3F48B@33958,4HF07@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator GHBLAFEN_01353 405566.lhv_1235 3.3e-164 584.3 Lactobacillaceae ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1TPH6@1239,3F3PJ@33958,4H9T8@91061,COG1227@1,COG1227@2 NA|NA|NA C inorganic pyrophosphatase GHBLAFEN_01354 405566.lhv_1236 5.9e-111 406.8 Lactobacillaceae ppiB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03768 ko00000,ko01000,ko03110 Bacteria 1TRHW@1239,3F3TI@33958,4H9V0@91061,COG0652@1,COG0652@2 NA|NA|NA G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides GHBLAFEN_01355 326425.lhe_1126 1.8e-54 218.4 Lactobacillaceae Bacteria 1UUUD@1239,3F8QF@33958,4I3X4@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix domain GHBLAFEN_01356 326425.lhe_1127 1.5e-85 322.4 Lactobacillaceae yoaK Bacteria 1V1VQ@1239,3F5F5@33958,4HM4F@91061,COG3619@1,COG3619@2 NA|NA|NA S Protein of unknown function (DUF1275) GHBLAFEN_01357 1423754.BALY01000067_gene768 7.2e-75 286.6 Lactobacillaceae Bacteria 1UZVH@1239,2BVJW@1,32QXP@2,3F6CN@33958,4HFK6@91061 NA|NA|NA S Uncharacterised protein family (UPF0236) GHBLAFEN_01358 1423748.BALB01000005_gene658 3.5e-138 497.7 Lactobacillaceae yxeH Bacteria 1TR16@1239,3F55S@33958,4HCZ6@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase GHBLAFEN_01359 1423748.BALB01000005_gene659 2.1e-36 157.9 Lactobacillaceae Bacteria 1U6CG@1239,2DKPU@1,30A92@2,3F7KQ@33958,4IG45@91061 NA|NA|NA S Enterocin A Immunity GHBLAFEN_01360 1423748.BALB01000005_gene660 6.3e-224 783.1 Lactobacillaceae psd 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR34@1239,3F5QB@33958,4HB6I@91061,COG0688@1,COG0688@2 NA|NA|NA I Belongs to the phosphatidylserine decarboxylase family GHBLAFEN_01361 326425.lhe_1574 4.4e-49 200.3 Lactobacillaceae pspC ko:K03973 ko00000,ko02048,ko03000 Bacteria 1VKBQ@1239,3F87Y@33958,4HRGW@91061,COG1983@1,COG1983@2 NA|NA|NA KT PspC domain GHBLAFEN_01363 326425.lhe_1572 6.4e-243 846.3 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1TQN0@1239,3F43S@33958,4HBD4@91061,COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family GHBLAFEN_01364 326425.lhe_1571 6.2e-154 550.1 Lactobacillaceae nnrD 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 1TNZE@1239,3F480@33958,4HBZC@91061,COG0063@1,COG0063@2 NA|NA|NA H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration GHBLAFEN_01365 326425.lhe_1570 1.5e-110 405.6 Lactobacillaceae Bacteria 1V4KP@1239,3F6PH@33958,4HIBF@91061,COG1376@1,COG1376@2 NA|NA|NA M ErfK YbiS YcfS YnhG GHBLAFEN_01366 405566.lhv_1703 6.1e-91 340.1 Lactobacillaceae padR Bacteria 1V5J2@1239,3FBD5@33958,4IPMM@91061,COG1695@1,COG1695@2 NA|NA|NA K Virulence activator alpha C-term GHBLAFEN_01367 326425.lhe_1568 2e-102 378.3 Lactobacillaceae padC ko:K13727 ko00000,ko01000 Bacteria 1UY0X@1239,3F4P4@33958,4HAN3@91061,COG3479@1,COG3479@2 NA|NA|NA Q Phenolic acid decarboxylase GHBLAFEN_01368 326425.lhe_1567 6.1e-111 406.8 Lactobacillaceae 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1A7@1239,3F655@33958,4HG0B@91061,COG5464@1,COG5464@2 NA|NA|NA S PD-(D/E)XK nuclease family transposase GHBLAFEN_01369 1423748.BALB01000005_gene673 2.2e-12 78.2 Lactobacillaceae 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1A7@1239,3F655@33958,4HG0B@91061,COG5464@1,COG5464@2 NA|NA|NA S PD-(D/E)XK nuclease family transposase GHBLAFEN_01370 405566.lhv_1699 0.0 1121.3 Lactobacillaceae argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPEZ@1239,3F4DE@33958,4HAR3@91061,COG0018@1,COG0018@2 NA|NA|NA J Arginyl-tRNA synthetase GHBLAFEN_01371 405566.lhv_1698 3.5e-171 607.4 Lactobacillaceae fba 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ01@1239,3F4EF@33958,4H9ZU@91061,COG0191@1,COG0191@2 NA|NA|NA G Fructose-1,6-bisphosphate aldolase, class II GHBLAFEN_01372 405566.lhv_1697 2.3e-90 338.2 Lactobacillaceae 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1V55F@1239,3F50F@33958,4HJEI@91061,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain GHBLAFEN_01373 326425.lhe_1563 2.1e-39 167.9 Lactobacillaceae Bacteria 1W6M0@1239,2ETIJ@1,33M2D@2,3F79G@33958,4IFY8@91061 NA|NA|NA GHBLAFEN_01374 326425.lhe_1562 1.7e-31 141.7 Lactobacillaceae Bacteria 1U8JH@1239,29QS7@1,30BS2@2,3FB1X@33958,4IIHG@91061 NA|NA|NA GHBLAFEN_01375 1423748.BALB01000008_gene928 1.1e-54 219.5 Lactobacillaceae Bacteria 1U5C8@1239,29NPN@1,309MJ@2,3F5HZ@33958,4IF3G@91061 NA|NA|NA GHBLAFEN_01376 326425.lhe_0193 1.4e-178 632.1 Lactobacillaceae ko:K22230 ko00562,ko01120,map00562,map01120 R09954 RC00182 ko00000,ko00001,ko01000 Bacteria 1TQSS@1239,3FCE9@33958,4HV6B@91061,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold GHBLAFEN_01377 405566.lhv_0193 7.4e-93 346.7 Lactobacillaceae gepA ko:K18830 ko00000,ko02048,ko03000 Bacteria 1UK2I@1239,3F4EH@33958,4ITGB@91061,COG2944@1,COG2944@2,COG3600@1,COG3600@2 NA|NA|NA K Protein of unknown function (DUF4065) GHBLAFEN_01378 405566.lhv_0193 1.1e-24 118.6 Lactobacillaceae gepA ko:K18830 ko00000,ko02048,ko03000 Bacteria 1UK2I@1239,3F4EH@33958,4ITGB@91061,COG2944@1,COG2944@2,COG3600@1,COG3600@2 NA|NA|NA K Protein of unknown function (DUF4065) GHBLAFEN_01379 405566.lhv_0192 0.0 1117.8 Lactobacillaceae yjbQ ko:K03455,ko:K03499 ko00000,ko02000 2.A.37,2.A.38.1,2.A.38.4 Bacteria 1TS32@1239,3F4AZ@33958,4H9Q5@91061,COG0475@1,COG0475@2,COG0569@1,COG0569@2 NA|NA|NA P TrkA C-terminal domain protein GHBLAFEN_01380 326425.lhe_0190 1.3e-209 735.3 Lactobacillaceae atl 3.2.1.96,3.5.1.28 ko:K01447,ko:K13714 R04112 RC00064,RC00141 ko00000,ko01000 GH73 Bacteria 1V3MY@1239,3F4BU@33958,4HBWG@91061,COG5632@1,COG5632@2 NA|NA|NA M N-acetylmuramoyl-L-alanine amidase GHBLAFEN_01381 326425.lhe_0189 3.7e-224 783.9 Lactobacillaceae ko:K02395 ko00000,ko02035 Bacteria 1TVPT@1239,3F4I7@33958,4HC0X@91061,COG1705@1,COG1705@2 NA|NA|NA NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase GHBLAFEN_01382 748671.LCRIS_00174 7.1e-26 123.2 Lactobacillaceae Bacteria 1U6KG@1239,3F83H@33958,4IGD9@91061,COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation GHBLAFEN_01383 748671.LCRIS_00174 5.4e-12 76.6 Lactobacillaceae Bacteria 1U6KG@1239,3F83H@33958,4IGD9@91061,COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation GHBLAFEN_01385 326425.lhe_0185 3.8e-166 591.3 Lactobacillaceae GO:0005575,GO:0005623,GO:0030115,GO:0030312,GO:0044464,GO:0071944 Bacteria 1U572@1239,2DHS4@1,300QQ@2,3F4ZW@33958,4IEYM@91061 NA|NA|NA S SLAP domain GHBLAFEN_01386 1423748.BALB01000008_gene913 1.3e-36 158.7 Bacilli Bacteria 1VKCM@1239,2DR42@1,33A2M@2,4HRAS@91061 NA|NA|NA S Protein of unknown function (DUF2922) GHBLAFEN_01387 405566.lhv_0182 1e-28 132.1 Lactobacillaceae Bacteria 1U6IH@1239,2AQKB@1,31FT9@2,3F7ZB@33958,4IGAU@91061 NA|NA|NA GHBLAFEN_01389 405566.lhv_0177 2.1e-73 281.6 Lactobacillaceae Bacteria 1U5KK@1239,29NU4@1,309S8@2,3F65J@33958,4IFBH@91061 NA|NA|NA GHBLAFEN_01390 1423748.BALB01000006_gene745 0.0 1278.8 Lactobacillaceae kup GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 ko:K03549 ko00000,ko02000 2.A.72 Bacteria 1TRUQ@1239,3F4CU@33958,4HA8Z@91061,COG3158@1,COG3158@2 NA|NA|NA P Transport of potassium into the cell GHBLAFEN_01391 326425.lhe_1828 0.0 3427.5 Lactobacillaceae prtS 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652,ko:K17734 ko00000,ko01000,ko01002,ko03110 Bacteria 1TPH1@1239,3F3M5@33958,4HBQH@91061,COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family GHBLAFEN_01392 326425.lhe_1829 3.6e-160 570.9 Lactobacillaceae prsA 5.2.1.8 ko:K02597,ko:K07533 ko00000,ko01000,ko03110 Bacteria 1VT0K@1239,3F4RW@33958,4I4BP@91061,COG0760@1,COG0760@2 NA|NA|NA M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins GHBLAFEN_01395 891391.LAC30SC_00345 1.4e-35 156.0 Lactobacillaceae Bacteria 1U580@1239,29NJD@1,309JD@2,3F53B@33958,4IEZA@91061 NA|NA|NA S Bacteriocin helveticin-J GHBLAFEN_01396 326425.lhe_0100 3.3e-119 434.5 Lactobacillaceae Bacteria 1U5EX@1239,2DKJ7@1,309P1@2,3F5TG@33958,4IF6H@91061 NA|NA|NA GHBLAFEN_01397 1033837.WANG_0286 6.2e-91 340.1 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3FCFA@33958,4HC8M@91061,COG2801@1,COG2801@2 NA|NA|NA L COG2963 Transposase and inactivated derivatives GHBLAFEN_01398 1033837.WANG_0286 2.7e-114 417.9 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3FCFA@33958,4HC8M@91061,COG2801@1,COG2801@2 NA|NA|NA L COG2963 Transposase and inactivated derivatives GHBLAFEN_01399 334390.LAF_0679 6.7e-140 503.4 Lactobacillaceae cylA ko:K01990,ko:K11050 ko02010,map02010 M00254,M00298 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.130 Bacteria 1V0AH@1239,3FBFC@33958,4HD15@91061,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system GHBLAFEN_01400 334390.LAF_0674 2.3e-99 368.2 Lactobacillaceae tnpR Bacteria 1TQAX@1239,3F429@33958,4HCFF@91061,COG1961@1,COG1961@2 NA|NA|NA L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed GHBLAFEN_01401 525365.HMPREF0548_1926 1.2e-87 329.3 Lactobacillaceae pbpX2 Bacteria 1U622@1239,3F6US@33958,4IFR2@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase GHBLAFEN_01402 405566.lhv_1782 2.5e-39 167.5 Lactobacillaceae 3.2.2.20 ko:K01246,ko:K06977 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V7GR@1239,3F44B@33958,4HJ11@91061,COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase GHBLAFEN_01403 326425.lhe_0439 1.1e-92 345.9 Lactobacillaceae Bacteria 1U63K@1239,2A3Q0@1,30S7H@2,3F6YD@33958,4IFT0@91061 NA|NA|NA GHBLAFEN_01404 1423748.BALB01000015_gene1399 1.9e-46 191.4 Lactobacillaceae Bacteria 1U54Y@1239,2DKHZ@1,309I2@2,3F4PH@33958,4IEW4@91061 NA|NA|NA GHBLAFEN_01405 1423748.BALB01000015_gene1399 6.7e-41 173.3 Lactobacillaceae Bacteria 1U54Y@1239,2DKHZ@1,309I2@2,3F4PH@33958,4IEW4@91061 NA|NA|NA GHBLAFEN_01406 1423748.BALB01000015_gene1398 5.6e-266 922.9 Lactobacillaceae aglB 3.2.1.122,3.2.1.86 ko:K01222,ko:K01232 ko00010,ko00500,map00010,map00500 R00837,R00838,R00839,R05133,R05134,R06113 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GH4,GT4 Bacteria 1TQ9I@1239,3F4W5@33958,4H9TM@91061,COG1486@1,COG1486@2 NA|NA|NA G Family 4 glycosyl hydrolase C-terminal domain GHBLAFEN_01407 1423748.BALB01000015_gene1397 1.8e-131 475.3 Lactobacillaceae glvR ko:K03481 ko00000,ko03000 Bacteria 1TR3Z@1239,3FBJI@33958,4IQVZ@91061,COG1737@1,COG1737@2 NA|NA|NA K Helix-turn-helix domain, rpiR family GHBLAFEN_01408 405566.lhv_1777 6e-188 663.3 Lactobacillaceae ansA 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 R00485 RC00010,RC02798 ko00000,ko00001,ko01000 Bacteria 1TPP9@1239,3FCC6@33958,4HD98@91061,COG0252@1,COG0252@2 NA|NA|NA EJ L-asparaginase, type I GHBLAFEN_01409 405566.lhv_2920 3.2e-15 86.7 Lactobacillaceae Bacteria 1U70J@1239,29PT6@1,30ARD@2,3F8TF@33958,4IGUW@91061 NA|NA|NA GHBLAFEN_01410 326425.lhe_0443 2.3e-19 100.5 Lactobacillaceae Bacteria 1U6DS@1239,29PBU@1,30AA1@2,3F7P4@33958,4IG5H@91061 NA|NA|NA GHBLAFEN_01411 1423748.BALB01000015_gene1395 1.1e-99 369.4 Lactobacillaceae 3.6.3.8 ko:K01537 ko00000,ko01000 3.A.3.2 Bacteria 1TPF5@1239,3F3KP@33958,4H9S5@91061,COG0474@1,COG0474@2 NA|NA|NA P P-type ATPase GHBLAFEN_01412 525365.HMPREF0548_1937 8.7e-119 433.3 Lactobacillaceae 3.6.3.8 ko:K01537 ko00000,ko01000 3.A.3.2 Bacteria 1TPF5@1239,3F3KP@33958,4H9S5@91061,COG0474@1,COG0474@2 NA|NA|NA P P-type ATPase GHBLAFEN_01413 405566.lhv_1776 1.4e-124 452.2 Lactobacillaceae Bacteria 1U591@1239,29NN1@1,309JZ@2,3F57G@33958,4IF0C@91061 NA|NA|NA GHBLAFEN_01414 405566.lhv_1775 7.2e-239 832.8 Lactobacillaceae Bacteria 1V6D3@1239,3F4ZG@33958,4IPQE@91061,COG4640@1,COG4640@2 NA|NA|NA S response to antibiotic GHBLAFEN_01415 405566.lhv_1774 1.4e-133 482.3 Lactobacillaceae cysA ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TNZG@1239,3F3MG@33958,4H9UT@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein GHBLAFEN_01416 405566.lhv_1773 0.0 1088.6 Lactobacillaceae ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TR2D@1239,3F45H@33958,4HAZG@91061,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family GHBLAFEN_01417 945021.TEH_22060 3.4e-50 204.5 Enterococcaceae asdA 4.1.1.12 ko:K09758 ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230 R00397,R00863 RC00282,RC00399,RC00400 ko00000,ko00001,ko01000 Bacteria 1TQP8@1239,4B107@81852,4HECY@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase class I and II GHBLAFEN_01418 1033837.WANG_0222 1.3e-51 208.8 Lactobacillaceae ko:K09155 ko00000 Bacteria 1TRD5@1239,3F45M@33958,4HAAW@91061,COG2461@1,COG2461@2 NA|NA|NA S PAS domain GHBLAFEN_01419 326425.lhe_1535 4.5e-188 663.7 Lactobacillaceae cbf ko:K03698 ko00000,ko01000,ko03019 Bacteria 1TPIU@1239,3F4SF@33958,4HB1M@91061,COG3481@1,COG3481@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. GHBLAFEN_01420 405566.lhv_1664 0.0 1182.2 Lactobacillaceae Bacteria 1TQP3@1239,3F3PF@33958,4HBCA@91061,COG0419@1,COG0419@2,COG4717@1,COG4717@2 NA|NA|NA L AAA domain GHBLAFEN_01421 405566.lhv_1665 1.7e-229 801.6 Lactobacillaceae yhaO ko:K03547 ko00000,ko03400 Bacteria 1TWMI@1239,3F3PX@33958,4HCA0@91061,COG0420@1,COG0420@2 NA|NA|NA L Ser Thr phosphatase family protein GHBLAFEN_01422 405566.lhv_1666 3.6e-55 220.7 Lactobacillaceae yheA Bacteria 1VASS@1239,3F822@33958,4HKKC@91061,COG3679@1,COG3679@2 NA|NA|NA S Belongs to the UPF0342 family GHBLAFEN_01423 405566.lhv_1667 0.0 1360.9 Lactobacillaceae pbp2A 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366,ko:K12555,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1TPM5@1239,3F49Q@33958,4H9SA@91061,COG0744@1,COG0744@2 NA|NA|NA M penicillin-binding protein GHBLAFEN_01424 405566.lhv_1668 2.4e-161 574.7 Lactobacillaceae rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 Bacteria 1TSM6@1239,3F50K@33958,4HA7M@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil GHBLAFEN_01425 1423748.BALB01000005_gene707 1.9e-09 67.4 Lactobacillaceae 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC4@1239,3F577@33958,4HJM8@91061,COG1304@1,COG1304@2 NA|NA|NA C FMN-dependent dehydrogenase GHBLAFEN_01426 326425.lhe_1542 1.3e-134 485.7 Lactobacillaceae mgtC ko:K07507 ko00000,ko02000 9.B.20 Bacteria 1V409@1239,3FB84@33958,4HC2G@91061,COG1285@1,COG1285@2 NA|NA|NA S MgtC family GHBLAFEN_01427 326425.lhe_1543 2.5e-138 498.0 Lactobacillaceae glpF ko:K02440 ko00000,ko02000 1.A.8.1,1.A.8.2 Bacteria 1TP4T@1239,3F4J6@33958,4HAWP@91061,COG0580@1,COG0580@2 NA|NA|NA U Belongs to the MIP aquaporin (TC 1.A.8) family GHBLAFEN_01428 326425.lhe_1544 4.9e-54 216.9 Lactobacillaceae Bacteria 1U624@1239,2AE03@1,313SN@2,3F6UV@33958,4IFR4@91061 NA|NA|NA GHBLAFEN_01429 326425.lhe_1545 9e-150 536.2 Lactobacillaceae citG 2.4.2.52,2.7.7.61 ko:K05966,ko:K13927,ko:K13930 ko02020,map02020 R09675,R10706 RC00049,RC00063 ko00000,ko00001,ko01000 Bacteria 1TQGQ@1239,3F4SU@33958,4HGCS@91061,COG1767@1,COG1767@2 NA|NA|NA H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase GHBLAFEN_01430 1423754.BALY01000032_gene469 7.9e-19 100.5 Lactobacillaceae ko:K15539 ko00000 Bacteria 1VSP5@1239,3F4FY@33958,4HUK1@91061,COG3266@1,COG3266@2 NA|NA|NA UW LPXTG-motif cell wall anchor domain protein GHBLAFEN_01432 326425.lhe_1549 2.3e-153 548.1 Lactobacillaceae yitS Bacteria 1TSKD@1239,3FBEP@33958,4HC4E@91061,COG1307@1,COG1307@2 NA|NA|NA S EDD domain protein, DegV family GHBLAFEN_01433 326425.lhe_1550 3.3e-83 314.3 Lactobacillaceae racA ko:K11686,ko:K13640,ko:K18997 ko00000,ko03000,ko03036 Bacteria 1V7Z4@1239,3F6W4@33958,4HPH8@91061,COG0789@1,COG0789@2 NA|NA|NA K Domain of unknown function (DUF1836) GHBLAFEN_01434 1423767.BALU01000011_gene260 3.8e-20 103.2 Lactobacillaceae Bacteria 1U6Z1@1239,29PRW@1,30AQ3@2,3F8R7@33958,4IGTB@91061 NA|NA|NA GHBLAFEN_01435 326425.lhe_1514 3.8e-195 687.2 Lactobacillaceae Bacteria 1U53C@1239,29NJD@1,309H9@2,3F4BP@33958,4IEUN@91061 NA|NA|NA S Bacteriocin helveticin-J GHBLAFEN_01436 326425.lhe_1515 7.9e-39 166.0 Lactobacillaceae Bacteria 1U6PC@1239,3F557@33958,4HDA6@91061,COG0308@1,COG0308@2 NA|NA|NA M Peptidase family M1 domain GHBLAFEN_01437 326425.lhe_1515 3.6e-142 510.8 Lactobacillaceae Bacteria 1U6PC@1239,3F557@33958,4HDA6@91061,COG0308@1,COG0308@2 NA|NA|NA M Peptidase family M1 domain GHBLAFEN_01438 326425.lhe_1515 7e-62 243.0 Lactobacillaceae Bacteria 1U6PC@1239,3F557@33958,4HDA6@91061,COG0308@1,COG0308@2 NA|NA|NA M Peptidase family M1 domain GHBLAFEN_01439 748671.LCRIS_01538 8.7e-176 622.9 Lactobacillaceae Bacteria 1U5FS@1239,29NRF@1,309PE@2,3F5V8@33958,4IF75@91061 NA|NA|NA S SLAP domain GHBLAFEN_01440 891391.LAC30SC_08515 9.7e-255 885.6 Lactobacillaceae mpl GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464 6.3.2.4,6.3.2.45,6.3.2.8 ko:K01921,ko:K01924,ko:K02558 ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502 R01150,R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iSDY_1059.SDY_4251 Bacteria 1TQ5H@1239,3F49J@33958,4HAR4@91061,COG0773@1,COG0773@2 NA|NA|NA M Belongs to the MurCDEF family GHBLAFEN_01441 1423748.BALB01000005_gene736 0.0 1135.9 Lactobacillaceae Bacteria 1UG8H@1239,29V6Q@1,30GKE@2,3F5M6@33958,4IF4J@91061 NA|NA|NA S SLAP domain GHBLAFEN_01442 326425.lhe_1524 3.3e-123 447.6 Lactobacillaceae pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890,ko:K06878 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1V7QA@1239,3FBJ0@33958,4HJBD@91061,COG0073@1,COG0073@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily GHBLAFEN_01443 326425.lhe_1525 7.3e-55 219.5 Lactobacillaceae ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 2.7.1.180,5.3.4.1 ko:K01829,ko:K03671,ko:K03734,ko:K06196 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko02000,ko03110 5.A.1.2 Bacteria 1VAS6@1239,3F72K@33958,4HKGM@91061,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin GHBLAFEN_01444 405566.lhv_1653 1e-124 452.6 Lactobacillaceae trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33 ko:K02493,ko:K03439 R10806 RC00003,RC03279 ko00000,ko01000,ko03012,ko03016 Bacteria 1TQCA@1239,3F3QM@33958,4HC08@91061,COG0220@1,COG0220@2 NA|NA|NA J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA GHBLAFEN_01445 326425.lhe_1527 1.7e-213 748.4 Lactobacillaceae ecsB ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1VG@1239,3F4HH@33958,4HG1K@91061,COG4473@1,COG4473@2 NA|NA|NA U ABC transporter GHBLAFEN_01446 326425.lhe_1528 3.9e-136 490.7 Lactobacillaceae ecsA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQIH@1239,3F444@33958,4HA2B@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter, ATP-binding protein GHBLAFEN_01447 405566.lhv_1657 3.8e-54 217.2 Lactobacillaceae higA ko:K18831,ko:K21498 ko00000,ko02048,ko03000 Bacteria 1U65V@1239,3F752@33958,4IFVU@91061,COG3093@1,COG3093@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins GHBLAFEN_01448 1423748.BALB01000005_gene721 3.4e-79 300.8 Lactobacillaceae hit ko:K02503 ko00000,ko04147 Bacteria 1V9ZJ@1239,3FCD7@33958,4HJ19@91061,COG0537@1,COG0537@2 NA|NA|NA FG Scavenger mRNA decapping enzyme C-term binding GHBLAFEN_01449 326425.lhe_1532 8e-28 129.8 Lactobacillaceae Bacteria 1U65N@1239,29P5R@1,30A3W@2,3F74E@33958,4IFVH@91061 NA|NA|NA GHBLAFEN_01450 1423748.BALB01000005_gene719 1.3e-154 552.4 Lactobacillaceae prsA 5.2.1.8 ko:K02597,ko:K07533 ko00000,ko01000,ko03110 Bacteria 1TX3R@1239,3FB3Y@33958,4HC85@91061,COG0760@1,COG0760@2 NA|NA|NA M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins GHBLAFEN_01451 1033837.WANG_1746 4.5e-29 133.3 Lactobacillaceae tnpR Bacteria 1UZM8@1239,3FBG8@33958,4IQ67@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain GHBLAFEN_01452 1423754.BALY01000024_gene999 1e-42 179.1 Lactobacillaceae ymdB Bacteria 1TPCU@1239,3F6GV@33958,4HIHC@91061,COG2110@1,COG2110@2 NA|NA|NA S Macro domain protein GHBLAFEN_01453 405566.lhv_1995 1.2e-152 545.8 Lactobacillaceae malG ko:K15772 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 Bacteria 1TRB7@1239,3F4NP@33958,4HC5K@91061,COG3833@1,COG3833@2 NA|NA|NA P ABC transporter permease GHBLAFEN_01454 326425.lhe_0254 2e-250 871.3 Lactobacillaceae malF ko:K02025,ko:K02026,ko:K15771 ko02010,map02010 M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2 Bacteria 1TR2A@1239,3F4J1@33958,4HB8H@91061,COG1175@1,COG1175@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component GHBLAFEN_01455 405566.lhv_1997 1.6e-211 741.9 Lactobacillaceae malE ko:K15770 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 Bacteria 1TPU9@1239,3F50T@33958,4HAK6@91061,COG2182@1,COG2182@2 NA|NA|NA G Bacterial extracellular solute-binding protein GHBLAFEN_01456 1423748.BALB01000024_gene1747 8.3e-207 726.1 Lactobacillaceae msmX ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko02000 3.A.1.1 Bacteria 1TP2M@1239,3FC3D@33958,4HAMQ@91061,COG3842@1,COG3842@2 NA|NA|NA P Belongs to the ABC transporter superfamily GHBLAFEN_01457 405566.lhv_1999 6.3e-117 426.8 Lactobacillaceae pgmB GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008801,GO:0009058,GO:0009292,GO:0009294,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016853,GO:0016866,GO:0016868,GO:0019203,GO:0030312,GO:0033554,GO:0034637,GO:0040007,GO:0042221,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046351,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0071704,GO:0071944,GO:1901576 2.4.1.64,3.1.3.12,3.2.1.28,5.4.2.6 ko:K01087,ko:K01194,ko:K01838,ko:K05342 ko00500,ko01100,map00500,map01100 R00010,R02727,R02728,R02778,R11310 RC00017,RC00049,RC00408 ko00000,ko00001,ko00537,ko01000 GH37,GH65 Bacteria 1UY8N@1239,3F4ST@33958,4HF3K@91061,COG0637@1,COG0637@2 NA|NA|NA S beta-phosphoglucomutase GHBLAFEN_01458 405566.lhv_2000 0.0 1547.7 Lactobacillaceae map2 2.4.1.8 ko:K00691 ko00500,ko01100,map00500,map01100 R01555 RC00049 ko00000,ko00001,ko01000 GH65 Bacteria 1TQMB@1239,3F3PG@33958,4HAVB@91061,COG1554@1,COG1554@2 NA|NA|NA G hydrolase, family 65, central catalytic GHBLAFEN_01459 326425.lhe_0249 0.0 1221.5 Lactobacillaceae nplT 3.2.1.133,3.2.1.135,3.2.1.54 ko:K01208 ko00500,ko01100,map00500,map01100 R02112,R03122,R11262 ko00000,ko00001,ko01000 GH13 Bacteria 1TNZ0@1239,3F41N@33958,4HB67@91061,COG0366@1,COG0366@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family GHBLAFEN_01460 326425.lhe_0248 0.0 1139.4 Lactobacillaceae malL 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13,GH31 Bacteria 1UY2T@1239,3FC10@33958,4HBRE@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain GHBLAFEN_01461 1423767.BALU01000001_gene1509 9.3e-45 186.0 Lactobacillaceae ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0409 Bacteria 1TQ22@1239,3F48Z@33958,4HA7K@91061,COG0282@1,COG0282@2 NA|NA|NA F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction GHBLAFEN_01462 326425.lhe_0257 1.9e-47 195.3 Bacteria 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria COG4932@1,COG4932@2 NA|NA|NA M domain protein GHBLAFEN_01463 525365.HMPREF0548_0786 8.8e-18 95.5 Lactobacillaceae Bacteria 1U6J6@1239,29PG8@1,30AED@2,3F80S@33958,4IGBQ@91061 NA|NA|NA GHBLAFEN_01464 405566.lhv_0672 3.4e-21 107.5 Lactobacillaceae XK27_01125 ko:K07484 ko00000 Bacteria 1V7U9@1239,3F6Q9@33958,4IR8Z@91061,COG3436@1,COG3436@2 NA|NA|NA L IS66 Orf2 like protein GHBLAFEN_01465 1423748.BALB01000022_gene1690 2.5e-48 198.0 Lactobacillaceae Bacteria 1UG8H@1239,29V6Q@1,30GKE@2,3F5M6@33958,4IF4J@91061 NA|NA|NA S SLAP domain GHBLAFEN_01466 1423748.BALB01000022_gene1690 6.8e-98 363.2 Lactobacillaceae Bacteria 1UG8H@1239,29V6Q@1,30GKE@2,3F5M6@33958,4IF4J@91061 NA|NA|NA S SLAP domain GHBLAFEN_01468 326425.lhe_1384 0.0 1173.7 Lactobacillaceae oppA ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1TQ0N@1239,3F3KW@33958,4HARF@91061,COG0747@1,COG0747@2 NA|NA|NA E ABC transporter substrate-binding protein GHBLAFEN_01469 326425.lhe_1383 2.1e-21 107.5 Lactobacillaceae Bacteria 1U799@1239,29PZS@1,30AY7@2,3F959@33958,4IH45@91061 NA|NA|NA GHBLAFEN_01470 326425.lhe_1382 9.8e-23 112.1 Lactobacillaceae Bacteria 1U6BY@1239,2CKSK@1,30A8J@2,3F7JR@33958,4IG3K@91061 NA|NA|NA GHBLAFEN_01471 326425.lhe_1381 1.7e-114 418.7 Lactobacillaceae papP ko:K02029 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TRU3@1239,3F3XD@33958,4HGE1@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter, permease protein GHBLAFEN_01472 326425.lhe_1380 4.8e-117 427.2 Lactobacillaceae ko:K02029,ko:K10040 ko02010,map02010 M00228,M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3 Bacteria 1TR7R@1239,3F45E@33958,4HGVA@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease GHBLAFEN_01473 326425.lhe_1379 8.2e-134 483.0 Lactobacillaceae glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,3FC3P@33958,4HDK7@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein GHBLAFEN_01474 525365.HMPREF0548_0230 1.7e-162 578.6 Lactobacillaceae cjaA ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TT11@1239,3F54P@33958,4HFBQ@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter substrate-binding protein GHBLAFEN_01475 525365.HMPREF0548_0229 2.5e-52 211.1 Lactobacillaceae ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1V9YV@1239,3F7D5@33958,4HKC6@91061,COG2151@1,COG2151@2 NA|NA|NA S Iron-sulfur cluster assembly protein GHBLAFEN_01476 525365.HMPREF0548_0228 9.5e-43 179.1 Lactobacillaceae sdaAA 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 1TP79@1239,3F3X8@33958,4HAI1@91061,COG1760@1,COG1760@2 NA|NA|NA E L-serine dehydratase, iron-sulfur-dependent, alpha subunit GHBLAFEN_01477 525365.HMPREF0548_0228 9.4e-91 339.7 Lactobacillaceae sdaAA 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 1TP79@1239,3F3X8@33958,4HAI1@91061,COG1760@1,COG1760@2 NA|NA|NA E L-serine dehydratase, iron-sulfur-dependent, alpha subunit GHBLAFEN_01478 525365.HMPREF0548_0227 7.1e-75 286.6 Lactobacillaceae sdaAB 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 1V8XQ@1239,3FC4T@33958,4HJWN@91061,COG1760@1,COG1760@2 NA|NA|NA E Serine dehydratase beta chain GHBLAFEN_01479 525365.HMPREF0548_0227 3.3e-14 84.0 Lactobacillaceae sdaAB 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 1V8XQ@1239,3FC4T@33958,4HJWN@91061,COG1760@1,COG1760@2 NA|NA|NA E Serine dehydratase beta chain GHBLAFEN_01480 525365.HMPREF0548_0226 9.7e-46 189.1 Lactobacillaceae Bacteria 1VNIV@1239,2CE9Z@1,33CNB@2,3F7UX@33958,4HRR9@91061 NA|NA|NA GHBLAFEN_01481 525365.HMPREF0548_0224 2.7e-96 358.6 Lactobacillaceae Bacteria 1U62I@1239,29XNY@1,30JEF@2,3F6VN@33958,4IFRN@91061 NA|NA|NA S Cysteine-rich secretory protein family GHBLAFEN_01482 525365.HMPREF0548_0223 4.3e-49 200.3 Lactobacillaceae Bacteria 1U62Q@1239,29P3D@1,30A1J@2,3F6W2@33958,4IFRV@91061 NA|NA|NA GHBLAFEN_01483 525365.HMPREF0548_0222 4.6e-206 723.8 Lactobacillaceae Bacteria 1TPJB@1239,3F4VX@33958,4HEY7@91061,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily GHBLAFEN_01484 525365.HMPREF0548_0221 1.5e-51 208.4 Lactobacillaceae Bacteria 1UPY3@1239,2DN64@1,32VRU@2,3FC0U@33958,4IVD5@91061 NA|NA|NA GHBLAFEN_01485 1033837.WANG_1777 6.2e-28 130.2 Lactobacillaceae bioY GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 ko:K03523 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 Bacteria 1VAAD@1239,3F6YG@33958,4HI8T@91061,COG1268@1,COG1268@2 NA|NA|NA S BioY family GHBLAFEN_01486 1033837.WANG_1776 1.1e-189 669.1 Lactobacillaceae birA 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 Bacteria 1TQCU@1239,3F5HY@33958,4HB60@91061,COG0340@1,COG0340@2 NA|NA|NA H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor GHBLAFEN_01487 1033837.WANG_1775 1.9e-133 481.9 Lactobacillaceae fabI GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPVD@1239,3F4AQ@33958,4H9YN@91061,COG0623@1,COG0623@2 NA|NA|NA I Enoyl- acyl-carrier-protein reductase NADH GHBLAFEN_01488 1033837.WANG_1774 4.1e-144 517.3 Lactobacillaceae accA 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHNS@1239,3F496@33958,4HA4C@91061,COG0825@1,COG0825@2 NA|NA|NA I alpha subunit GHBLAFEN_01489 1033837.WANG_1773 6e-157 560.1 Lactobacillaceae accD 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4U@1239,3F3T6@33958,4HAI7@91061,COG0777@1,COG0777@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA GHBLAFEN_01490 1033837.WANG_1772 1.5e-258 898.3 Lactobacillaceae accC GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iSF_1195.SF3294 Bacteria 1TP16@1239,3F3PT@33958,4HARK@91061,COG0439@1,COG0439@2 NA|NA|NA I Acetyl-CoA carboxylase biotin carboxylase subunit GHBLAFEN_01491 1033837.WANG_1771 1.7e-72 278.5 Lactobacillaceae fabZ 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 1VXBZ@1239,3F6TF@33958,4HXVK@91061,COG0764@1,COG0764@2 NA|NA|NA I FabA-like domain GHBLAFEN_01492 1033837.WANG_1770 3.7e-79 300.8 Lactobacillaceae accB 2.3.1.12,4.1.1.3 ko:K00627,ko:K01571,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00217,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 Bacteria 1VAB7@1239,3F7M1@33958,4HKCS@91061,COG0511@1,COG0511@2 NA|NA|NA I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA GHBLAFEN_01493 1033837.WANG_1769 2.5e-228 797.7 Lactobacillaceae fabF 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPA7@1239,3F51H@33958,4H9SD@91061,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP GHBLAFEN_01494 326425.lhe_0286 8.6e-128 463.0 Lactobacillaceae Bacteria 1TP76@1239,3F4RI@33958,4HAA6@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase GHBLAFEN_01495 1033837.WANG_1767 2.8e-168 597.8 Lactobacillaceae fabD 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPB7@1239,3F3W9@33958,4HBCU@91061,COG0331@1,COG0331@2 NA|NA|NA I Malonyl CoA-acyl carrier protein transacylase GHBLAFEN_01496 1033837.WANG_1766 4.9e-35 153.3 Lactobacillaceae acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 1VGIY@1239,3F7ZJ@33958,4HP0V@91061,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis GHBLAFEN_01497 326425.lhe_0283 1e-179 636.0 Lactobacillaceae fabH 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TP0K@1239,3F3XP@33958,4HATK@91061,COG0332@1,COG0332@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids GHBLAFEN_01498 1033837.WANG_1764 3.6e-79 300.8 Lactobacillaceae marR Bacteria 1VCUU@1239,3FC7K@33958,4HIUM@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator GHBLAFEN_01499 1033837.WANG_1763 3.8e-78 297.4 Lactobacillaceae fabZ 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 1V3UN@1239,3FCD6@33958,4HHYD@91061,COG0764@1,COG0764@2 NA|NA|NA I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs GHBLAFEN_01500 1033837.WANG_1761 6.2e-147 526.9 Lactobacillaceae pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 R01570,R01876,R02296,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 iHN637.CLJU_RS08925 Bacteria 1TPCH@1239,3F45P@33958,4H9NP@91061,COG0213@1,COG0213@2 NA|NA|NA F pyrimidine-nucleoside phosphorylase GHBLAFEN_01501 1033837.WANG_1747 7e-13 79.7 Lactobacillaceae ytgB Bacteria 1VENK@1239,3F7EK@33958,4HNKV@91061,COG2261@1,COG2261@2 NA|NA|NA S Transglycosylase associated protein GHBLAFEN_01502 797515.HMPREF9103_01291 1.8e-44 184.9 Lactobacillaceae hprA 1.1.1.29 ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCX@1239,3F4Z6@33958,4HASY@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family GHBLAFEN_01503 1267003.KB911433_gene1240 1.2e-46 192.2 Lactobacillaceae Bacteria 1VI8G@1239,2EIVY@1,33CM8@2,3FBQ2@33958,4HY2K@91061 NA|NA|NA GHBLAFEN_01504 1138822.PL11_10545 8.9e-53 212.6 Lactobacillaceae Bacteria 1W2PF@1239,28WF1@1,2ZIF8@2,3F8BE@33958,4HZUK@91061 NA|NA|NA GHBLAFEN_01505 324831.LGAS_1688 5.1e-68 264.2 Lactobacillaceae ptsG 2.7.1.199,2.7.1.208 ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.3 Bacteria 1TPJ8@1239,3F44V@33958,4HA8X@91061,COG1263@1,COG1263@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system, EIIB GHBLAFEN_01506 1033837.WANG_1178 4e-218 763.8 Lactobacillaceae naiP Bacteria 1TQM0@1239,3F3SE@33958,4HATA@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GHBLAFEN_01507 1033837.WANG_1177 0.0 1241.5 Lactobacillaceae XK27_00340 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPV2@1239,3F4S2@33958,4HB9S@91061,COG0737@1,COG0737@2 NA|NA|NA F Belongs to the 5'-nucleotidase family GHBLAFEN_01508 1033837.WANG_1176 6.1e-291 1006.1 Lactobacillaceae oppA ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F5SJ@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter GHBLAFEN_01509 1033837.WANG_1533 5.8e-214 750.0 Lactobacillaceae Bacteria 1TQQ0@1239,3F4D3@33958,4HDKW@91061,COG1228@1,COG1228@2 NA|NA|NA Q Imidazolonepropionase and related amidohydrolases GHBLAFEN_01510 1033837.WANG_1173 3e-61 241.1 Lactobacillaceae psiE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K13256 ko00000 Bacteria 1VCG5@1239,3FBQN@33958,4HKQN@91061,COG3223@1,COG3223@2 NA|NA|NA S Phosphate-starvation-inducible E GHBLAFEN_01512 405566.lhv_1501 3e-223 780.8 Lactobacillaceae galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TPD0@1239,3F3Q9@33958,4HARP@91061,COG0153@1,COG0153@2 NA|NA|NA F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) GHBLAFEN_01513 326425.lhe_1409 1.5e-285 988.0 Lactobacillaceae galT 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPBN@1239,3F4D8@33958,4HAYJ@91061,COG4468@1,COG4468@2 NA|NA|NA G UDP-glucose--hexose-1-phosphate uridylyltransferase GHBLAFEN_01514 405566.lhv_1499 5.9e-196 689.9 Lactobacillaceae galM 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQGJ@1239,3F48R@33958,4HADZ@91061,COG2017@1,COG2017@2 NA|NA|NA G Catalyzes the interconversion of alpha and beta anomers of maltose GHBLAFEN_01515 1033837.WANG_1110 3.2e-222 777.7 Lactobacillaceae Bacteria 1TSRV@1239,3F46B@33958,4HCIZ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC-type multidrug transport system, ATPase and permease components GHBLAFEN_01516 1033837.WANG_1111 1.7e-19 101.3 Lactobacillaceae Bacteria 1TSRV@1239,3F46B@33958,4HCIZ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC-type multidrug transport system, ATPase and permease components GHBLAFEN_01518 1423748.BALB01000006_gene832 1.4e-33 148.3 Lactobacillaceae Bacteria 1USWD@1239,2930D@1,3270J@2,3F7S4@33958,4IG6X@91061 NA|NA|NA GHBLAFEN_01520 405566.lhv_0095 2.2e-131 474.9 Lactobacillaceae Bacteria 1TPQG@1239,3F4FB@33958,4HA8Q@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator GHBLAFEN_01521 326425.lhe_0107 2e-306 1057.7 Lactobacillaceae vicK 2.7.13.3 ko:K07652 ko02020,map02020 M00459 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQ1H@1239,3F45G@33958,4HA52@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase GHBLAFEN_01522 1423748.BALB01000006_gene828 6.7e-243 846.3 Lactobacillaceae yycH Bacteria 1V32Y@1239,3F4HR@33958,4HG2Q@91061,COG4863@1,COG4863@2 NA|NA|NA S YycH protein GHBLAFEN_01523 1423748.BALB01000006_gene827 2.7e-146 524.6 Lactobacillaceae yycI Bacteria 1V1FW@1239,3F3PV@33958,4HFWZ@91061,COG4853@1,COG4853@2 NA|NA|NA S YycH protein GHBLAFEN_01524 405566.lhv_0099 3.3e-149 534.3 Lactobacillaceae vicX 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 1TQ8E@1239,3F3S4@33958,4HAKD@91061,COG1235@1,COG1235@2 NA|NA|NA S domain protein GHBLAFEN_01525 405566.lhv_0100 1.4e-181 642.5 Lactobacillaceae htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04691,ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1TRM8@1239,3F45X@33958,4HA31@91061,COG0265@1,COG0265@2 NA|NA|NA O serine protease GHBLAFEN_01526 1423748.BALB01000006_gene823 4.3e-91 340.9 Lactobacillaceae rlmH 2.1.1.177 ko:K00783 ko00000,ko01000,ko03009 Bacteria 1V3JM@1239,3F3YX@33958,4HFP8@91061,COG1576@1,COG1576@2 NA|NA|NA J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA GHBLAFEN_01527 1033837.WANG_1650 5.6e-38 163.7 Lactobacillaceae Bacteria 1U6FR@1239,3F7TF@33958,4IG7Q@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins GHBLAFEN_01528 525365.HMPREF0548_1817 2e-24 118.6 Lactobacillaceae Bacteria 1U6FR@1239,3F7TF@33958,4IG7Q@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins GHBLAFEN_01530 176090.SSIN_1052 3.9e-82 311.6 Bacilli ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPBQ@1239,4HEPD@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter GHBLAFEN_01531 1046629.Ssal_00303 9.2e-40 170.6 Bacilli ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1VA63@1239,2CSEJ@1,32SR2@2,4HMDZ@91061 NA|NA|NA GHBLAFEN_01532 936140.AEOT01000010_gene496 5.6e-30 136.7 Lactobacillaceae higA ko:K21498 ko00000,ko02048 Bacteria 1VCFB@1239,3F7RE@33958,4IG6K@91061,COG3093@1,COG3093@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins GHBLAFEN_01533 405566.lhv_0102 6.3e-173 613.2 Lactobacillaceae pepI 3.4.11.5,3.5.1.101 ko:K01259,ko:K18457 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 1TRMT@1239,3F40N@33958,4HE23@91061,COG2267@1,COG2267@2 NA|NA|NA E Releases the N-terminal proline from various substrates GHBLAFEN_01534 405566.lhv_0103 1.3e-90 339.3 Lactobacillaceae ko:K16785 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1V2VE@1239,3FBE3@33958,4IPQA@91061,COG0619@1,COG0619@2 NA|NA|NA P Cobalt transport protein GHBLAFEN_01535 326425.lhe_0117 1.4e-245 855.1 Lactobacillaceae cbiO1 ko:K05776,ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00189,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1UI2R@1239,3F3WM@33958,4ISG8@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein GHBLAFEN_01536 405566.lhv_0105 1.9e-172 611.7 Lactobacillaceae Bacteria 1VCUV@1239,3F48T@33958,4HGUV@91061,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein GHBLAFEN_01537 1423754.BALY01000006_gene1344 7e-37 159.5 Lactobacillaceae Bacteria 1TQEG@1239,3F43M@33958,4HD6M@91061,COG2801@1,COG2801@2 NA|NA|NA L hmm pf00665 GHBLAFEN_01538 1423754.BALY01000006_gene1344 2.3e-36 158.3 Lactobacillaceae Bacteria 1TQEG@1239,3F43M@33958,4HD6M@91061,COG2801@1,COG2801@2 NA|NA|NA L hmm pf00665 GHBLAFEN_01539 1423754.BALY01000006_gene1344 1.3e-60 238.8 Lactobacillaceae Bacteria 1TQEG@1239,3F43M@33958,4HD6M@91061,COG2801@1,COG2801@2 NA|NA|NA L hmm pf00665 GHBLAFEN_01540 1423754.BALY01000006_gene1343 2.7e-113 414.8 Lactobacillaceae ko:K07483 ko00000 Bacteria 1V1QC@1239,3F65F@33958,4HH7E@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain GHBLAFEN_01541 405566.lhv_0108 3.9e-162 577.4 Lactobacillaceae htpX ko:K03799 M00743 ko00000,ko00002,ko01000,ko01002 Bacteria 1TP23@1239,3F40Z@33958,4HB11@91061,COG0501@1,COG0501@2 NA|NA|NA O Belongs to the peptidase M48B family GHBLAFEN_01542 405566.lhv_0109 2.3e-96 358.2 Lactobacillaceae lemA ko:K03744 ko00000 Bacteria 1V4SV@1239,3FBKP@33958,4IR1I@91061,COG1704@1,COG1704@2 NA|NA|NA S LemA family GHBLAFEN_01543 405566.lhv_0110 9.8e-192 676.0 Lactobacillaceae ybiR GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1TQCH@1239,3F4CJ@33958,4HEW7@91061,COG1055@1,COG1055@2 NA|NA|NA P Citrate transporter GHBLAFEN_01544 1033837.WANG_1663 7.7e-70 269.6 Lactobacillaceae Bacteria 1VY7K@1239,2F916@1,341CT@2,3F70S@33958,4HX4B@91061 NA|NA|NA S Iron-sulphur cluster biosynthesis GHBLAFEN_01545 1033837.WANG_1664 1e-60 239.6 Lactobacillaceae glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1UGF1@1239,3FC1C@33958,4HBM4@91061,COG0584@1,COG0584@2,COG4781@1,COG4781@2 NA|NA|NA C Membrane domain of glycerophosphoryl diester phosphodiesterase GHBLAFEN_01546 1033837.WANG_1664 4.5e-236 823.5 Lactobacillaceae glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1UGF1@1239,3FC1C@33958,4HBM4@91061,COG0584@1,COG0584@2,COG4781@1,COG4781@2 NA|NA|NA C Membrane domain of glycerophosphoryl diester phosphodiesterase GHBLAFEN_01547 1033837.WANG_1665 1.2e-17 94.7 Lactobacillaceae Bacteria 1U6MZ@1239,29PIJ@1,30AGQ@2,3F868@33958,4IGEU@91061 NA|NA|NA GHBLAFEN_01548 1033837.WANG_1666 2.4e-121 441.4 Lactobacillaceae yfbR ko:K07023 ko00000 Bacteria 1TSDU@1239,3F4RZ@33958,4HA8H@91061,COG1896@1,COG1896@2 NA|NA|NA S HD containing hydrolase-like enzyme GHBLAFEN_01549 1033837.WANG_1667 6.3e-162 576.6 Lactobacillaceae Bacteria 1V4V2@1239,3F4P0@33958,4HI4X@91061,COG1403@1,COG1403@2 NA|NA|NA L HNH nucleases GHBLAFEN_01550 1033837.WANG_1668 8.1e-137 493.0 Lactobacillaceae glnQ ko:K17074,ko:K17076 ko02010,map02010 M00589 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.20 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein GHBLAFEN_01551 326425.lhe_0132 4.1e-287 993.4 Lactobacillaceae glnP ko:K02029,ko:K02030,ko:K17073,ko:K17074 ko02010,map02010 M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1TPM3@1239,3F48Y@33958,4HAS2@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2 NA|NA|NA P ABC transporter permease GHBLAFEN_01552 326425.lhe_0133 1.5e-120 438.7 Lactobacillaceae mpg GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1E6@1239,3F59D@33958,4HG5E@91061,COG2094@1,COG2094@2 NA|NA|NA L Belongs to the DNA glycosylase MPG family GHBLAFEN_01553 326425.lhe_0134 1.8e-62 245.0 Lactobacillaceae yeaO Bacteria 1VABH@1239,3F715@33958,4HKI2@91061,COG3189@1,COG3189@2 NA|NA|NA S Protein of unknown function, DUF488 GHBLAFEN_01554 405566.lhv_0126 2.5e-120 438.3 Lactobacillaceae terC ko:K05794 ko00000 Bacteria 1TQ09@1239,3FB68@33958,4HB99@91061,COG0861@1,COG0861@2 NA|NA|NA P Integral membrane protein TerC family GHBLAFEN_01555 405566.lhv_0127 3.5e-91 340.9 Lactobacillaceae ogt 2.1.1.63 ko:K00567,ko:K10778,ko:K13531 ko00000,ko01000,ko03000,ko03400 Bacteria 1VA03@1239,3F4TG@33958,4HETA@91061,COG0350@1,COG0350@2 NA|NA|NA L 6-O-methylguanine DNA methyltransferase, DNA binding domain GHBLAFEN_01556 405566.lhv_0128 1.2e-124 452.6 Lactobacillaceae cobB ko:K12410 ko00000,ko01000 Bacteria 1TQKD@1239,3F4WS@33958,4HC4I@91061,COG0846@1,COG0846@2 NA|NA|NA K SIR2 family GHBLAFEN_01557 405566.lhv_0129 3.5e-85 320.9 Lactobacillaceae Bacteria 1U58T@1239,2CCJZ@1,303JM@2,3F565@33958,4IF00@91061 NA|NA|NA GHBLAFEN_01558 405566.lhv_0130 1.7e-284 984.6 Lactobacillaceae cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPKY@1239,3F3SF@33958,4H9TI@91061,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol GHBLAFEN_01559 326425.lhe_0140 6.8e-178 629.8 Lactobacillaceae Bacteria 1UY1T@1239,3F5D8@33958,4I2Y3@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF915) GHBLAFEN_01560 326425.lhe_0141 2.1e-145 521.5 Lactobacillaceae rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469,ko:K06993 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1V4A0@1239,3F3RG@33958,4HHJ9@91061,COG0328@1,COG0328@2,COG3341@1,COG3341@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids GHBLAFEN_01561 405566.lhv_0133 2.7e-137 495.0 Lactobacillaceae ypuA Bacteria 1UY79@1239,3F416@33958,4HAZ5@91061,COG4086@1,COG4086@2 NA|NA|NA S Protein of unknown function (DUF1002) GHBLAFEN_01562 405566.lhv_0134 1.2e-159 568.9 Lactobacillaceae epsV 2.7.8.12 ko:K09809 ko00000,ko01000 Bacteria 1VATJ@1239,3F52I@33958,4HNAP@91061,COG1216@1,COG1216@2 NA|NA|NA S glycosyl transferase family 2 GHBLAFEN_01563 326425.lhe_0144 5.6e-126 456.8 Lactobacillaceae Bacteria 1TSFW@1239,3F5BW@33958,4HI0M@91061,COG0596@1,COG0596@2 NA|NA|NA S Alpha/beta hydrolase family GHBLAFEN_01564 326425.lhe_0145 1.5e-115 422.2 Lactobacillaceae Bacteria 1UJSC@1239,3F4ZZ@33958,4HCVT@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family GHBLAFEN_01565 326425.lhe_0146 2.5e-55 221.5 Lactobacillaceae Bacteria 1U6HK@1239,29PF3@1,30AD9@2,3F7XT@33958,4IG9W@91061 NA|NA|NA GHBLAFEN_01566 405566.lhv_0137 1.4e-181 642.1 Lactobacillaceae prs 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2848 Bacteria 1TQ6Q@1239,3F3V8@33958,4HB61@91061,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) GHBLAFEN_01567 405566.lhv_0138 8.7e-122 443.0 Lactobacillaceae luxT Bacteria 1VZKY@1239,3F43G@33958,4HM1C@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family GHBLAFEN_01568 326425.lhe_0149 1e-129 469.5 Lactobacillaceae Bacteria 1U516@1239,2CCK0@1,309GI@2,3F3YE@33958,4IESZ@91061 NA|NA|NA GHBLAFEN_01569 326425.lhe_0150 3.5e-261 907.1 Lactobacillaceae glnPH2 ko:K02029,ko:K02030,ko:K17073,ko:K17074 ko02010,map02010 M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1TPM3@1239,3F48Y@33958,4HAS2@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2 NA|NA|NA P ABC transporter permease GHBLAFEN_01570 326425.lhe_0151 1.1e-133 482.6 Lactobacillaceae glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein GHBLAFEN_01571 326425.lhe_0152 3.2e-231 807.4 Lactobacillaceae Bacteria 1V1IM@1239,3F3QG@33958,4HRX1@91061,COG2340@1,COG2340@2 NA|NA|NA S Cysteine-rich secretory protein family GHBLAFEN_01572 1423748.BALB01000006_gene775 2.4e-206 724.5 Lactobacillaceae ddl 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TP2Y@1239,3F41Z@33958,4H9KB@91061,COG1181@1,COG1181@2 NA|NA|NA F Belongs to the D-alanine--D-alanine ligase family GHBLAFEN_01573 1423748.BALB01000006_gene774 5.7e-95 354.0 Lactobacillaceae Bacteria 1VN62@1239,2EIZT@1,33CQY@2,3F5GU@33958,4HRPP@91061 NA|NA|NA GHBLAFEN_01574 405566.lhv_0145 5.9e-200 703.4 Lactobacillaceae yibE Bacteria 1TPEV@1239,3F3M9@33958,4HCP3@91061,COG5438@1,COG5438@2 NA|NA|NA S overlaps another CDS with the same product name GHBLAFEN_01575 326425.lhe_0156 2.2e-129 468.4 Lactobacillaceae yibF Bacteria 1TSWX@1239,3F3S6@33958,4HBKX@91061,COG5438@1,COG5438@2 NA|NA|NA S overlaps another CDS with the same product name GHBLAFEN_01576 326425.lhe_0157 3.8e-156 557.4 Lactobacillaceae Bacteria 1V212@1239,3FBE2@33958,4HGWT@91061,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold GHBLAFEN_01577 1423748.BALB01000006_gene770 4.9e-31 139.8 Lactobacillaceae Bacteria 1U6R2@1239,2DKRT@1,30AIP@2,3F8CA@33958,4IGIC@91061 NA|NA|NA GHBLAFEN_01578 405566.lhv_0152 0.0 2038.5 Lactobacillaceae Bacteria 1TR8N@1239,3FC1B@33958,4HEJM@91061,COG1501@1,COG1501@2 NA|NA|NA G Belongs to the glycosyl hydrolase 31 family GHBLAFEN_01579 405566.lhv_0153 5.7e-80 303.5 Lactobacillaceae ntd 2.4.2.6 ko:K08728 ko00240,map00240 R02806 RC00063 ko00000,ko00001,ko01000 Bacteria 1VY4Q@1239,3F5CB@33958,4HXB4@91061,COG3613@1,COG3613@2 NA|NA|NA F Nucleoside GHBLAFEN_01580 405566.lhv_0154 5.4e-81 307.0 Lactobacillaceae 2.7.1.200,2.7.1.202,2.7.1.204 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K20112 ko00051,ko00052,ko01100,ko01120,ko02060,map00051,map00052,map01100,map01120,map02060 M00273,M00279,M00807 R03232,R05570,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.5,4.A.5.1 Bacteria 1V8H9@1239,3F4A7@33958,4HK36@91061,COG1762@1,COG1762@2 NA|NA|NA G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 GHBLAFEN_01581 326425.lhe_0162 1.4e-147 528.9 Lactobacillaceae ptp3 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1V851@1239,3F55V@33958,4HJB2@91061,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family GHBLAFEN_01582 326425.lhe_0163 5.5e-86 323.6 Lactobacillaceae uspA ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1VEJR@1239,3F4Z0@33958,4HNHG@91061,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein GHBLAFEN_01584 326425.lhe_0164 6e-150 537.0 Lactobacillaceae phnD ko:K02044 ko02010,map02010 M00223 ko00000,ko00001,ko00002,ko02000 3.A.1.9 Bacteria 1TR0H@1239,3F3KK@33958,4HBJQ@91061,COG3221@1,COG3221@2 NA|NA|NA P Phosphonate ABC transporter GHBLAFEN_01585 326425.lhe_0165 5.7e-138 496.9 Lactobacillaceae phnC GO:0006810,GO:0008150,GO:0015716,GO:0051179,GO:0051234,GO:0071702 3.6.3.28 ko:K02041 ko02010,map02010 M00223 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 Bacteria 1TQG6@1239,3F3SJ@33958,4HC3N@91061,COG3638@1,COG3638@2 NA|NA|NA P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system GHBLAFEN_01586 326425.lhe_0166 1.6e-127 462.2 Lactobacillaceae phnE 3.6.1.63 ko:K02042,ko:K06162 ko00440,ko02010,map00440,map02010 M00223 R10186 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 Bacteria 1TR1S@1239,3F58M@33958,4HBT8@91061,COG3639@1,COG3639@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component GHBLAFEN_01587 405566.lhv_0160 4.6e-146 523.9 Lactobacillaceae phnE 3.6.1.63 ko:K02042,ko:K06162 ko00440,ko02010,map00440,map02010 M00223 R10186 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 Bacteria 1V15B@1239,3F4TN@33958,4IQWU@91061,COG3639@1,COG3639@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component GHBLAFEN_01588 405566.lhv_0161 7.8e-108 396.4 Lactobacillaceae tag 3.2.2.20 ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1UYWG@1239,3F5KA@33958,4HGWW@91061,COG2818@1,COG2818@2 NA|NA|NA L glycosylase GHBLAFEN_01589 326425.lhe_0169 1.1e-81 309.3 Lactobacillaceae Bacteria 1U5KG@1239,2CCK1@1,309S4@2,3F64Y@33958,4IFBA@91061 NA|NA|NA GHBLAFEN_01590 405566.lhv_0163 1.1e-272 945.3 Lactobacillaceae Bacteria 1VMH1@1239,2EQYH@1,33II5@2,3F5E7@33958,4HUIK@91061 NA|NA|NA S Calcineurin-like phosphoesterase GHBLAFEN_01591 405566.lhv_0164 0.0 1334.7 Lactobacillaceae asnB 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 1TRPB@1239,3FB65@33958,4HA44@91061,COG0367@1,COG0367@2 NA|NA|NA E Asparagine synthase GHBLAFEN_01592 326425.lhe_0172 1.4e-253 881.7 Lactobacillaceae yxbA 6.3.1.12 ko:K17810 ko00000,ko01000 Bacteria 1TQPN@1239,3F3S7@33958,4HAB0@91061,COG3919@1,COG3919@2 NA|NA|NA S ATP-grasp enzyme GHBLAFEN_01595 326425.lhe_0174 0.0 1541.9 Lactobacillaceae nrdD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019001,GO:0019103,GO:0019438,GO:0019637,GO:0019692,GO:0030554,GO:0031250,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032556,GO:0032558,GO:0032559,GO:0032560,GO:0032564,GO:0032567,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0046872,GO:0046914,GO:0051065,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_4713,iPC815.YPO3454 Bacteria 1TR9K@1239,3F435@33958,4HBIY@91061,COG1328@1,COG1328@2 NA|NA|NA F Ribonucleoside-triphosphate reductase GHBLAFEN_01596 326425.lhe_0175 4.3e-140 503.8 Lactobacillaceae nrdG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0031250,GO:0032991,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 1.97.1.4 ko:K04068 R04710 ko00000,ko01000 iE2348C_1286.E2348C_4563 Bacteria 1V1HG@1239,3F46H@33958,4HGJ9@91061,COG0602@1,COG0602@2 NA|NA|NA O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine GHBLAFEN_01597 326425.lhe_0176 7.8e-100 369.8 Lactobacillaceae ko:K02612,ko:K09155 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1V9YV@1239,3F7D5@33958,4HKC6@91061,COG2151@1,COG2151@2,COG2461@1,COG2461@2 NA|NA|NA S Iron-sulfur cluster assembly protein GHBLAFEN_01598 326425.lhe_0177 7.5e-230 802.7 Lactobacillaceae XK27_04775 ko:K09155 ko00000 Bacteria 1TRD5@1239,3F45M@33958,4HAAW@91061,COG2461@1,COG2461@2 NA|NA|NA S PAS domain GHBLAFEN_01599 405566.lhv_0173 5.7e-225 786.6 Lactobacillaceae yttB Bacteria 1TPJ6@1239,3F4F9@33958,4HAGJ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GHBLAFEN_01600 326425.lhe_0179 0.0 1298.5 Lactobacillaceae pepO 3.4.24.71 ko:K01415,ko:K07386 ko00000,ko01000,ko01002,ko04147 Bacteria 1TQTA@1239,3F4CX@33958,4HDSF@91061,COG3590@1,COG3590@2 NA|NA|NA O Peptidase family M13 GHBLAFEN_01601 326425.lhe_0973 2.6e-113 414.8 Lactobacillaceae hlyIII ko:K11068 ko00000,ko02042 Bacteria 1TSFK@1239,3F578@33958,4HAT2@91061,COG1272@1,COG1272@2 NA|NA|NA S protein, hemolysin III GHBLAFEN_01602 326425.lhe_0974 2.9e-148 531.2 Lactobacillaceae DegV Bacteria 1TRM7@1239,3FC90@33958,4HBIR@91061,COG1307@1,COG1307@2 NA|NA|NA S Uncharacterised protein, DegV family COG1307 GHBLAFEN_01603 326425.lhe_0975 9.3e-36 155.6 Lactobacillaceae yozE Bacteria 1VFI4@1239,3F7ZP@33958,4HR7P@91061,COG4479@1,COG4479@2 NA|NA|NA S Belongs to the UPF0346 family GHBLAFEN_01604 405566.lhv_1070 6.8e-279 966.1 Lactobacillaceae yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 1TR4G@1239,3F42V@33958,4HBJR@91061,COG0025@1,COG0025@2 NA|NA|NA P Sodium proton antiporter GHBLAFEN_01605 405566.lhv_1071 1.2e-157 562.4 Lactobacillaceae ylqF GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 ko:K14540 ko00000,ko03009 Bacteria 1TQGK@1239,3F3MI@33958,4HA4D@91061,COG1161@1,COG1161@2 NA|NA|NA S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity GHBLAFEN_01606 405566.lhv_1072 3.7e-134 484.2 Lactobacillaceae rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1V1D6@1239,3F3JC@33958,4HB7M@91061,COG0164@1,COG0164@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids GHBLAFEN_01607 326425.lhe_0979 5.6e-155 553.5 Lactobacillaceae dprA GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 ko:K04096 ko00000 Bacteria 1TPP7@1239,3F41U@33958,4HGWM@91061,COG0758@1,COG0758@2 NA|NA|NA LU DNA protecting protein DprA GHBLAFEN_01608 326425.lhe_0980 0.0 1319.3 Lactobacillaceae topA 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria 1TPUS@1239,3F3VS@33958,4HA6C@91061,COG0550@1,COG0550@2 NA|NA|NA L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone GHBLAFEN_01609 326425.lhe_0981 2.6e-247 860.9 Lactobacillaceae trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 ko00000,ko01000,ko03016,ko03036 Bacteria 1TP67@1239,3F3WW@33958,4HB27@91061,COG1206@1,COG1206@2 NA|NA|NA J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs GHBLAFEN_01610 326425.lhe_0982 4.3e-169 600.5 Lactobacillaceae xerC ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 1TQRG@1239,3FBHU@33958,4IQMI@91061,COG4974@1,COG4974@2 NA|NA|NA D Phage integrase, N-terminal SAM-like domain GHBLAFEN_01611 326425.lhe_0983 3e-90 337.8 Lactobacillaceae hslV GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 ko:K01419 ko00000,ko01000,ko01002 Bacteria 1TPXK@1239,3F4HS@33958,4H9PD@91061,COG5405@1,COG5405@2 NA|NA|NA O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery GHBLAFEN_01612 326425.lhe_0984 1.9e-232 811.6 Lactobacillaceae hslU GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03667 ko00000,ko03110 Bacteria 1TPKQ@1239,3F3WB@33958,4HA83@91061,COG1220@1,COG1220@2 NA|NA|NA O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis GHBLAFEN_01613 405566.lhv_1079 6.1e-176 623.2 Lactobacillaceae lacX 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 1U26T@1239,3F3KT@33958,4HA4J@91061,COG2017@1,COG2017@2 NA|NA|NA G Aldose 1-epimerase GHBLAFEN_01614 326425.lhe_0220 3.3e-216 757.7 Lactobacillaceae cycA GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease GHBLAFEN_01615 405566.lhv_2039 1.9e-245 854.7 Lactobacillaceae yifK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03293 ko00000 2.A.3.1 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease GHBLAFEN_01616 1033837.WANG_1611 1.5e-14 85.1 Lactobacillaceae puuD ko:K07010 ko00000,ko01002 Bacteria 1V1KC@1239,3F4PK@33958,4HI59@91061,COG2071@1,COG2071@2 NA|NA|NA S peptidase C26 GHBLAFEN_01617 1423748.BALB01000014_gene1320 3.8e-106 391.0 Lactobacillaceae steT_1 Bacteria 1UZNT@1239,3F3SX@33958,4HFMI@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid GHBLAFEN_01618 405566.lhv_2034 2e-191 674.9 Lactobacillaceae asnA GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 R00483 RC00010 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299 Bacteria 1TP28@1239,3F40A@33958,4HAEC@91061,COG2502@1,COG2502@2 NA|NA|NA F aspartate--ammonia ligase GHBLAFEN_01619 326425.lhe_0228 2.6e-202 711.1 Lactobacillaceae 4.2.1.126 ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 R08555 RC00397,RC00746 ko00000,ko00001,ko01000 Bacteria 1TRIY@1239,3FB4D@33958,4HAHJ@91061,COG3589@1,COG3589@2 NA|NA|NA S Bacterial protein of unknown function (DUF871) GHBLAFEN_01622 405566.lhv_2031 1.3e-182 645.6 Lactobacillaceae guaC 1.1.1.205,1.7.1.7 ko:K00088,ko:K00364 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R01134,R08240 RC00143,RC00457,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iSB619.SA_RS06660 Bacteria 1TNYF@1239,3F45K@33958,4HA55@91061,COG0516@1,COG0516@2 NA|NA|NA F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides GHBLAFEN_01623 326425.lhe_0232 1.6e-246 858.2 Lactobacillaceae purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ4C@1239,3F3RQ@33958,4H9YT@91061,COG0104@1,COG0104@2 NA|NA|NA F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP GHBLAFEN_01624 1033837.WANG_1421 5.8e-244 849.7 Lactobacillaceae purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1095 Bacteria 1TPMM@1239,3F48P@33958,4HACW@91061,COG0015@1,COG0015@2 NA|NA|NA F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily GHBLAFEN_01625 405566.lhv_2904 6.1e-58 229.9 Lactobacillaceae Bacteria 1U5UZ@1239,29NYM@1,309WQ@2,3F6IU@33958,4IFIM@91061 NA|NA|NA GHBLAFEN_01626 326425.lhe_0235 2.9e-84 317.8 Lactobacillaceae Bacteria 1U5Q4@1239,2DKKP@1,309U8@2,3F6AJ@33958,4IFEC@91061 NA|NA|NA GHBLAFEN_01627 748671.LCRIS_01927 3.4e-32 144.1 Lactobacillaceae yheS_2 ko:K18231,ko:K19349,ko:K19350 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 3.A.1.121,3.A.1.121.1,3.A.1.121.2,3.A.1.121.3 Bacteria 1TQNA@1239,3F4UR@33958,4H9VW@91061,COG0488@1,COG0488@2 NA|NA|NA S ATPases associated with a variety of cellular activities GHBLAFEN_01628 1423790.BN53_01340 2.4e-74 285.4 Lactobacillaceae Bacteria 1V3S1@1239,3F6JQ@33958,4HHI0@91061,COG2267@1,COG2267@2 NA|NA|NA I Alpha/beta hydrolase family GHBLAFEN_01629 525365.HMPREF0548_1206 8.7e-19 99.0 Lactobacillaceae Bacteria 1VQW3@1239,3F64W@33958,4HV4F@91061,COG2364@1,COG2364@2 NA|NA|NA S Membrane GHBLAFEN_01630 891391.LAC30SC_02505 5.2e-49 201.1 Lactobacillaceae Bacteria 1U6GA@1239,3F7UU@33958,4IG8E@91061,COG2364@1,COG2364@2 NA|NA|NA S Membrane GHBLAFEN_01631 525365.HMPREF0548_1193 6.6e-124 450.3 Lactobacillaceae Bacteria 1TPGA@1239,3F4HK@33958,4HER3@91061,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase GHBLAFEN_01632 525365.HMPREF0548_1199 4.1e-143 514.2 Lactobacillaceae proX ko:K05845 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1TQ7D@1239,3FB49@33958,4HESS@91061,COG1732@1,COG1732@2 NA|NA|NA M ABC transporter, substrate-binding protein, QAT family GHBLAFEN_01633 525365.HMPREF0548_1200 7e-89 333.6 Lactobacillaceae proWZ ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1V41S@1239,3FB48@33958,4HH8U@91061,COG1174@1,COG1174@2 NA|NA|NA P ABC transporter permease GHBLAFEN_01634 525365.HMPREF0548_1201 3.8e-110 404.4 Lactobacillaceae proV ko:K05847 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1TPV8@1239,3F55H@33958,4H9SI@91061,COG1125@1,COG1125@2 NA|NA|NA E ABC transporter, ATP-binding protein GHBLAFEN_01635 525365.HMPREF0548_1202 8.5e-87 326.6 Lactobacillaceae proW ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1UHWH@1239,3F5XQ@33958,4HJIP@91061,COG1174@1,COG1174@2 NA|NA|NA P ABC transporter, permease protein GHBLAFEN_01636 525365.HMPREF0548_1192 1.3e-60 239.2 Lactobacillaceae yyaQ Bacteria 1V4K7@1239,3F73S@33958,4IFV9@91061,COG2315@1,COG2315@2 NA|NA|NA S YjbR GHBLAFEN_01637 1280.SAXN108_2711 6.9e-07 60.1 Staphylococcaceae ko:K19158 ko00000,ko01000,ko02048 Bacteria 1VAM5@1239,4GZK4@90964,4HRX3@91061,COG4115@1,COG4115@2 NA|NA|NA S ParE toxin of type II toxin-antitoxin system, parDE GHBLAFEN_01638 525365.HMPREF0548_1209 2.2e-63 248.4 Lactobacillaceae mta ko:K11923 ko00000,ko03000 Bacteria 1TS86@1239,3F6G4@33958,4HJAU@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance GHBLAFEN_01639 525365.HMPREF0548_1209 8.6e-38 162.9 Lactobacillaceae mta ko:K11923 ko00000,ko03000 Bacteria 1TS86@1239,3F6G4@33958,4HJAU@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance GHBLAFEN_01640 326425.lhe_1031 6.8e-95 353.2 Lactobacillaceae yyaR ko:K06889 ko00000 Bacteria 1V6YX@1239,3F6BG@33958,4IQXU@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain GHBLAFEN_01641 405566.lhv_1132 0.0 1656.3 Lactobacillaceae uvrA3 ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TP0A@1239,3F3V4@33958,4HTDZ@91061,COG0178@1,COG0178@2 NA|NA|NA L excinuclease ABC, A subunit GHBLAFEN_01644 326425.lhe_1035 1.7e-105 388.7 Lactobacillaceae rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 1U7FQ@1239,3F9JR@33958,4IHBR@91061,COG0127@1,COG0127@2 NA|NA|NA F Ham1 family GHBLAFEN_01645 1423748.BALB01000002_gene283 1.3e-265 921.8 Lactobacillaceae pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 1TRJN@1239,3F49B@33958,4HBZ9@91061,COG3579@1,COG3579@2 NA|NA|NA E Peptidase C1-like family GHBLAFEN_01646 1033837.WANG_0042 1.1e-145 522.7 Lactobacillaceae glcU ko:K05340 ko00000,ko02000 2.A.7.5 Bacteria 1TQBN@1239,3F4K2@33958,4HAVH@91061,COG4975@1,COG4975@2 NA|NA|NA U sugar transport GHBLAFEN_01647 1423758.BN55_01900 2.3e-09 67.4 Lactobacillaceae Bacteria 1VKTU@1239,2DS5S@1,33ENY@2,3F6MW@33958,4HSXX@91061 NA|NA|NA GHBLAFEN_01648 1033837.WANG_0040 0.0 1687.9 Lactobacillaceae mgtA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132 3.6.3.2,3.6.3.6 ko:K01531,ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 3.A.3.3,3.A.3.4 iSF_1195.SF4248 Bacteria 1TPF5@1239,3F4E0@33958,4HBQJ@91061,COG0474@1,COG0474@2 NA|NA|NA P COG0474 Cation transport ATPase GHBLAFEN_01649 1033837.WANG_0039 2.1e-114 418.3 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TRNY@1239,3F55P@33958,4HBKP@91061,COG0675@1,COG0675@2 NA|NA|NA L transposase, IS605 OrfB family GHBLAFEN_01650 1033837.WANG_0039 6.2e-105 386.7 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TRNY@1239,3F55P@33958,4HBKP@91061,COG0675@1,COG0675@2 NA|NA|NA L transposase, IS605 OrfB family GHBLAFEN_01651 1033837.WANG_0038 1.6e-182 645.2 Lactobacillaceae Bacteria 1TQKR@1239,3F51A@33958,4HF9B@91061,COG4639@1,COG4639@2 NA|NA|NA S AAA domain GHBLAFEN_01652 405566.lhv_0354 8.3e-125 453.0 Lactobacillaceae gpmA GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1V2UT@1239,3F443@33958,4HGRK@91061,COG0588@1,COG0588@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate GHBLAFEN_01653 326425.lhe_1741 5.5e-23 112.8 Lactobacillaceae Bacteria 1U6P8@1239,29PJE@1,30AHJ@2,3F88U@33958,4IGG9@91061 NA|NA|NA GHBLAFEN_01654 405566.lhv_0353 6e-163 580.1 Lactobacillaceae czcD ko:K16264 ko00000,ko02000 2.A.4.1 Bacteria 1TR92@1239,3F4KJ@33958,4HBCQ@91061,COG1230@1,COG1230@2 NA|NA|NA P cation diffusion facilitator family transporter GHBLAFEN_01655 1423748.BALB01000002_gene290 2e-126 458.4 Lactobacillaceae pgm3 Bacteria 1TQF1@1239,3F4RY@33958,4I2XH@91061,COG0406@1,COG0406@2 NA|NA|NA G Belongs to the phosphoglycerate mutase family GHBLAFEN_01656 1423748.BALB01000003_gene465 5.5e-81 307.0 Lactobacillaceae Bacteria 1TPU2@1239,3F53G@33958,4HG2E@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator GHBLAFEN_01657 1423748.BALB01000003_gene466 1.3e-50 205.7 Lactobacillaceae sptS 2.7.13.3 ko:K11328 ko02020,map02020 M00464 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1UHQH@1239,3F4JY@33958,4HAHG@91061,COG0642@1,COG0642@2 NA|NA|NA T Histidine kinase GHBLAFEN_01658 1423748.BALB01000003_gene466 6.1e-116 423.7 Lactobacillaceae sptS 2.7.13.3 ko:K11328 ko02020,map02020 M00464 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1UHQH@1239,3F4JY@33958,4HAHG@91061,COG0642@1,COG0642@2 NA|NA|NA T Histidine kinase GHBLAFEN_01659 405566.lhv_1489 2.1e-208 731.5 Lactobacillaceae Bacteria 1TQHD@1239,3F43Q@33958,4HX8J@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GHBLAFEN_01660 326425.lhe_1402 9.2e-71 272.7 Lactobacillaceae Bacteria 1VN90@1239,3F6MQ@33958,4HRIC@91061,COG1765@1,COG1765@2 NA|NA|NA O OsmC-like protein GHBLAFEN_01661 405566.lhv_1487 5.1e-125 453.8 Lactobacillaceae dkgA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 1U59X@1239,3F5BI@33958,4IF1F@91061,COG0656@1,COG0656@2 NA|NA|NA S L-ascorbic acid biosynthetic process GHBLAFEN_01662 405566.lhv_1486 5e-89 334.3 Lactobacillaceae Bacteria 1U575@1239,29NM6@1,309J4@2,3F507@33958,4IEYP@91061 NA|NA|NA GHBLAFEN_01664 525365.HMPREF0548_0256 6.1e-74 283.9 Lactobacillaceae Bacteria 1W1FZ@1239,2FIUN@1,34AK2@2,3F4EU@33958,4HYXZ@91061 NA|NA|NA GHBLAFEN_01665 748671.LCRIS_01394 1.7e-60 238.8 Lactobacillaceae Bacteria 1W1FZ@1239,2FIUN@1,34AK2@2,3F4EU@33958,4HYXZ@91061 NA|NA|NA GHBLAFEN_01666 1423748.BALB01000003_gene474 3.9e-39 167.2 Lactobacillaceae Bacteria 1W1FZ@1239,2FIUN@1,34AK2@2,3F4EU@33958,4HYXZ@91061 NA|NA|NA GHBLAFEN_01667 1423748.BALB01000003_gene475 5.8e-272 943.0 Lactobacillaceae yjeM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1TRFS@1239,3F4J0@33958,4HA0N@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid GHBLAFEN_01668 1423748.BALB01000003_gene476 1.8e-89 335.1 Lactobacillaceae luxS GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300 Bacteria 1V1CH@1239,3F4W2@33958,4HFPR@91061,COG1854@1,COG1854@2 NA|NA|NA H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) GHBLAFEN_01669 1423748.BALB01000003_gene477 1e-68 266.2 Lactobacillaceae yxjG 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPDQ@1239,3F49P@33958,4HADW@91061,COG0620@1,COG0620@2 NA|NA|NA E methionine synthase, vitamin-B12 independent GHBLAFEN_01670 1423748.BALB01000003_gene477 1e-114 419.5 Lactobacillaceae yxjG 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPDQ@1239,3F49P@33958,4HADW@91061,COG0620@1,COG0620@2 NA|NA|NA E methionine synthase, vitamin-B12 independent GHBLAFEN_01673 1423748.BALB01000003_gene479 2.9e-90 337.8 Lactobacillaceae Bacteria 1U53J@1239,29NJI@1,309HE@2,3F4CT@33958,4IEUW@91061 NA|NA|NA GHBLAFEN_01674 1400520.LFAB_09215 5.3e-232 810.1 Lactobacillaceae cps4J Bacteria 1TRRI@1239,3F47P@33958,4IEU9@91061,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein GHBLAFEN_01675 1400520.LFAB_09220 3.1e-184 651.0 Firmicutes 2.1.1.21,6.3.5.4 ko:K01953,ko:K22081 ko00250,ko00680,ko01100,ko01110,ko01120,map00250,map00680,map01100,map01110,map01120 R00578,R01586 RC00010,RC00554 ko00000,ko00001,ko01000,ko01002 Bacteria 1UPH9@1239,COG0367@1,COG0367@2 NA|NA|NA E Asparagine synthase GHBLAFEN_01676 1400520.LFAB_09225 1.8e-74 285.0 Lactobacillaceae tagD 2.7.7.15,2.7.7.39 ko:K00968,ko:K00980 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 M00090 R00856,R01890,R02590 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3KY@1239,3F8KC@33958,4HW66@91061,COG0615@1,COG0615@2 NA|NA|NA IM Cytidylyltransferase-like GHBLAFEN_01677 1400520.LFAB_09230 1.1e-231 808.9 Lactobacillaceae Bacteria 1V2N4@1239,3FBDT@33958,4IPPY@91061,COG1887@1,COG1887@2 NA|NA|NA M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase GHBLAFEN_01678 1400520.LFAB_09235 3.5e-134 484.2 Lactobacillaceae Bacteria 1V3YG@1239,3FBMN@33958,4IR6T@91061,COG3774@1,COG3774@2 NA|NA|NA M Glycosyltransferase sugar-binding region containing DXD motif GHBLAFEN_01679 1400520.LFAB_09240 1.4e-188 665.6 Lactobacillaceae Bacteria 1U7UH@1239,2BSYD@1,32N26@2,3FA6Z@33958,4IHRW@91061 NA|NA|NA S EpsG family GHBLAFEN_01680 1400520.LFAB_09245 1.4e-152 545.4 Lactobacillaceae epsE ko:K19423 ko00000,ko01000,ko01003 GT2 Bacteria 1UZYU@1239,3F6ND@33958,4HQ2D@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 GHBLAFEN_01681 1400520.LFAB_09250 4.3e-206 723.8 Lactobacillaceae Bacteria 1TRCM@1239,3F6H1@33958,4HC0S@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 GHBLAFEN_01682 1400520.LFAB_09255 3.9e-119 434.1 Lactobacillaceae rfbP Bacteria 1TP7M@1239,3F51J@33958,4HCBG@91061,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase GHBLAFEN_01683 1400520.LFAB_09260 1.1e-20 105.1 Lactobacillaceae ywqE 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1TQ1T@1239,3F3RT@33958,4HDZR@91061,COG4464@1,COG4464@2 NA|NA|NA GM PHP domain protein GHBLAFEN_01684 220668.lp_1197 6.3e-92 343.6 Lactobacillaceae epsB Bacteria 1UZCR@1239,3F4M5@33958,4HE26@91061,COG3944@1,COG3944@2 NA|NA|NA M biosynthesis protein GHBLAFEN_01686 935836.JAEL01000201_gene4586 1.6e-08 63.5 Bacillus Bacteria 1TZQ8@1239,1ZJ4J@1386,2AWWM@1,31NU5@2,4II4F@91061 NA|NA|NA GHBLAFEN_01688 326425.lhe_1798 2.9e-81 307.8 Lactobacillaceae yebR 1.8.4.14 ko:K08968 ko00270,map00270 R02025 RC00639 ko00000,ko00001,ko01000 Bacteria 1V6GQ@1239,3F6NT@33958,4HH7X@91061,COG1956@1,COG1956@2 NA|NA|NA T GAF domain-containing protein GHBLAFEN_01689 326425.lhe_1797 0.0 1518.1 Lactobacillaceae clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 1TPMU@1239,3F3RV@33958,4HACY@91061,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE GHBLAFEN_01690 405566.lhv_0302 0.0 2364.7 Lactobacillaceae rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TP96@1239,3F4ET@33958,4H9PK@91061,COG0085@1,COG0085@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates GHBLAFEN_01691 405566.lhv_0303 0.0 2417.1 Lactobacillaceae rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TNYT@1239,3F3KF@33958,4HA24@91061,COG0086@1,COG0086@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates GHBLAFEN_01692 326425.lhe_0196 2.4e-23 114.0 Bacteria ykuL Bacteria COG0517@1,COG0517@2 NA|NA|NA S IMP dehydrogenase activity GHBLAFEN_01693 326425.lhe_0197 2.7e-213 747.7 Lactobacillaceae ywhK Bacteria 1V841@1239,3F50M@33958,4HITC@91061,COG3391@1,COG3391@2 NA|NA|NA S Membrane GHBLAFEN_01694 326425.lhe_0198 3.8e-50 203.8 Lactobacillaceae Bacteria 1U67F@1239,29P6X@1,30A50@2,3F78Y@33958,4IFXY@91061 NA|NA|NA GHBLAFEN_01695 525365.HMPREF0548_1419 5.2e-19 99.4 Lactobacillaceae Bacteria 1U6IK@1239,2DKQV@1,30ADX@2,3F7ZM@33958,4IGAZ@91061 NA|NA|NA S D-Ala-teichoic acid biosynthesis protein GHBLAFEN_01696 326425.lhe_0200 5.1e-292 1009.6 Lactobacillaceae dltA 6.1.1.13 ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1TPTH@1239,3F49R@33958,4HAHU@91061,COG1020@1,COG1020@2 NA|NA|NA H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall GHBLAFEN_01697 405566.lhv_2059 3e-237 827.4 Lactobacillaceae dltB ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1TP52@1239,3F4KK@33958,4HBQG@91061,COG1696@1,COG1696@2 NA|NA|NA M MBOAT, membrane-bound O-acyltransferase family GHBLAFEN_01698 326425.lhe_0202 2.2e-35 154.5 Lactobacillaceae dltC GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K02078,ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1VFQI@1239,3F7Q1@33958,4HNIH@91061,COG0236@1,COG0236@2 NA|NA|NA J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall GHBLAFEN_01699 1423748.BALB01000014_gene1343 1.3e-240 838.6 Lactobacillaceae dltD ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1TSZU@1239,3F3WE@33958,4HC3H@91061,COG3966@1,COG3966@2 NA|NA|NA M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) GHBLAFEN_01700 1423748.BALB01000014_gene1342 7.9e-174 616.3 Lactobacillaceae pbpX2 ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1V0GX@1239,3F4TH@33958,4HCXH@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase GHBLAFEN_01702 97137.C821_01144 4.1e-11 73.6 Lactobacillaceae Bacteria 1U5GX@1239,2DKJE@1,309Q1@2,3F5X8@33958,4IF7Q@91061 NA|NA|NA GHBLAFEN_01703 326425.lhe_0205 3.2e-119 434.5 Lactobacillaceae ko:K07052 ko00000 Bacteria 1VNA9@1239,3F5T9@33958,4HRMP@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity GHBLAFEN_01704 324831.LGAS_0137 1.7e-29 135.6 Lactobacillaceae Bacteria 1U65S@1239,2CHFN@1,30A3Z@2,3F74U@33958,4IFVM@91061 NA|NA|NA GHBLAFEN_01705 326425.lhe_0207 1.8e-32 144.8 Lactobacillaceae Bacteria 1U6PF@1239,29PJF@1,30AHK@2,3F894@33958,4IGGE@91061 NA|NA|NA GHBLAFEN_01706 326425.lhe_0208 9.6e-16 88.6 Lactobacillaceae Bacteria 1U737@1239,29PVC@1,30ATK@2,3F8X4@33958,4IGXS@91061 NA|NA|NA GHBLAFEN_01707 326425.lhe_0209 2.5e-121 441.4 Lactobacillaceae Bacteria 1V6FC@1239,3FBKG@33958,4HPG8@91061,COG5523@1,COG5523@2 NA|NA|NA S Protein of unknown function (DUF975) GHBLAFEN_01708 1423748.BALB01000024_gene1755 1e-111 409.5 Lactobacillaceae ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0409 Bacteria 1TQ22@1239,3F991@33958,4HA7K@91061,COG0282@1,COG0282@2 NA|NA|NA H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction GHBLAFEN_01709 326425.lhe_0246 8.5e-176 622.9 Lactobacillaceae yvdE ko:K02529 ko00000,ko03000 Bacteria 1U6Z4@1239,3F3ZC@33958,4HC2A@91061,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor GHBLAFEN_01710 326425.lhe_0245 3.6e-148 530.8 Lactobacillaceae ptp2 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1W78R@1239,3F4QQ@33958,4IEVA@91061,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family GHBLAFEN_01711 748671.LCRIS_01907 1.5e-228 798.5 Lactobacillaceae glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPX3@1239,3F3WI@33958,4H9ZF@91061,COG0554@1,COG0554@2 NA|NA|NA F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate GHBLAFEN_01712 326425.lhe_0243 5.6e-152 543.5 Lactobacillaceae thiD GO:0008150,GO:0040007 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 ko:K00941,ko:K03147,ko:K21219 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R03472,R04509,R10712 RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ4A@1239,3F3NA@33958,4HAAH@91061,COG0351@1,COG0351@2 NA|NA|NA H Phosphomethylpyrimidine kinase GHBLAFEN_01714 326425.lhe_0242 1.2e-131 475.7 Lactobacillaceae cobQ ko:K07009 ko00000 Bacteria 1U7I9@1239,3F4CH@33958,4HD1P@91061,COG3442@1,COG3442@2 NA|NA|NA S glutamine amidotransferase GHBLAFEN_01715 405566.lhv_2023 1.2e-82 312.4 Lactobacillaceae Bacteria 1V9ZW@1239,3FC1P@33958,4HZ6Z@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family GHBLAFEN_01716 405566.lhv_2024 7.8e-150 536.6 Lactobacillaceae Bacteria 1TRTP@1239,3FBJS@33958,4HB3F@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family GHBLAFEN_01717 326425.lhe_0239 5.5e-110 403.7 Lactobacillaceae Bacteria 1UQ43@1239,2A5BR@1,30U1B@2,3F6BQ@33958,4IFET@91061 NA|NA|NA GHBLAFEN_01718 326425.lhe_0238 6.9e-78 297.0 Lactobacillaceae Bacteria 1U5BC@1239,29NPC@1,309M9@2,3F5FH@33958,4IF2P@91061 NA|NA|NA GHBLAFEN_01719 326425.lhe_0237 2.7e-183 647.9 Lactobacillaceae XK27_05540 Bacteria 1UR34@1239,3F4J5@33958,4HDF2@91061,COG1434@1,COG1434@2 NA|NA|NA S DUF218 domain GHBLAFEN_01720 748671.LCRIS_01927 7.1e-80 303.5 Lactobacillaceae yheS_2 ko:K18231,ko:K19349,ko:K19350 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 3.A.1.121,3.A.1.121.1,3.A.1.121.2,3.A.1.121.3 Bacteria 1TQNA@1239,3F4UR@33958,4H9VW@91061,COG0488@1,COG0488@2 NA|NA|NA S ATPases associated with a variety of cellular activities GHBLAFEN_01721 748671.LCRIS_01413 2e-44 184.9 Lactobacillaceae lacZ 3.2.1.23 ko:K12308 ko00052,map00052 R01105 RC00452 ko00000,ko00001,ko01000 Bacteria 1TQN6@1239,3F3PC@33958,4HARI@91061,COG1874@1,COG1874@2 NA|NA|NA G -beta-galactosidase GHBLAFEN_01722 405566.lhv_1542 3.8e-89 334.0 Lactobacillaceae lacZ 3.2.1.23 ko:K12308 ko00052,map00052 R01105 RC00452 ko00000,ko00001,ko01000 Bacteria 1TQN6@1239,3F3PC@33958,4HARI@91061,COG1874@1,COG1874@2 NA|NA|NA G -beta-galactosidase GHBLAFEN_01723 405566.lhv_1543 0.0 1214.1 Lactobacillaceae lacS ko:K03292,ko:K11104,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.1,2.A.2.2 Bacteria 1TRA5@1239,3F3P7@33958,4HCDS@91061,COG2190@1,COG2190@2,COG2211@1,COG2211@2 NA|NA|NA G Transporter GHBLAFEN_01724 1033837.WANG_0295 1.2e-141 509.6 Lactobacillaceae lacS ko:K03292,ko:K11104,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.1,2.A.2.2 Bacteria 1TRA5@1239,3F3P7@33958,4HCDS@91061,COG2190@1,COG2190@2,COG2211@1,COG2211@2 NA|NA|NA G Transporter GHBLAFEN_01725 525365.HMPREF0548_0295 1.4e-48 198.7 Lactobacillaceae lacS ko:K03292,ko:K11104,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.1,2.A.2.2 Bacteria 1TRA5@1239,3F3P7@33958,4HCDS@91061,COG2190@1,COG2190@2,COG2211@1,COG2211@2 NA|NA|NA G Transporter GHBLAFEN_01726 326425.lhe_1439 2.1e-24 117.9 Lactobacillaceae lacS ko:K03292,ko:K11104,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.1,2.A.2.2 Bacteria 1TRA5@1239,3F3P7@33958,4HCDS@91061,COG2190@1,COG2190@2,COG2211@1,COG2211@2 NA|NA|NA G Transporter GHBLAFEN_01727 405566.lhv_1547 1.2e-188 665.6 Lactobacillaceae lacR ko:K02529 ko00000,ko03000 Bacteria 1TPZJ@1239,3F3PB@33958,4HC9Z@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator GHBLAFEN_01728 326425.lhe_1442 0.0 1325.8 Lactobacillaceae lacL 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 Bacteria 1TPDC@1239,3F4EI@33958,4HANW@91061,COG3250@1,COG3250@2 NA|NA|NA G Belongs to the glycosyl hydrolase 2 family GHBLAFEN_01729 326425.lhe_1443 1.7e-187 661.8 Lactobacillaceae lacM 3.2.1.23,3.2.1.35,3.2.1.51,3.2.1.97 ko:K01190,ko:K01197,ko:K01206,ko:K17624 ko00052,ko00511,ko00531,ko00600,ko01100,map00052,map00511,map00531,map00600,map01100 M00076,M00077 R01105,R01678,R03355,R04783,R06114,R07824,R07825,R10905 RC00049,RC00452 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042,ko04147 GH101,GH29 Bacteria 1TRVA@1239,3F51Z@33958,4HFMH@91061,COG3250@1,COG3250@2 NA|NA|NA G beta-galactosidase GHBLAFEN_01730 326425.lhe_1444 1.2e-191 675.6 Lactobacillaceae galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ7N@1239,3F3YF@33958,4H9U5@91061,COG1087@1,COG1087@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family GHBLAFEN_01731 326425.lhe_1641 6.9e-150 536.6 Lactobacillaceae yumC GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 1.18.1.2,1.19.1.1,1.8.1.9 ko:K00384,ko:K21567 ko00450,map00450 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 iYO844.BSU32110 Bacteria 1TRPN@1239,3F3NQ@33958,4H9V7@91061,COG0492@1,COG0492@2 NA|NA|NA C Ferredoxin--NADP reductase GHBLAFEN_01732 326425.lhe_1642 1.8e-116 425.2 Lactobacillaceae dedA ko:K03975 ko00000 Bacteria 1UZ4P@1239,3F4KG@33958,4HG3F@91061,COG0586@1,COG0586@2 NA|NA|NA S SNARE-like domain protein GHBLAFEN_01733 326425.lhe_1643 2.2e-84 318.5 Lactobacillaceae Bacteria 1V7UW@1239,3F4YP@33958,4HHH4@91061,COG4478@1,COG4478@2 NA|NA|NA S Protein of unknown function (DUF1461) GHBLAFEN_01734 326425.lhe_1644 1.5e-146 525.4 Lactobacillaceae nagD 2.7.1.25,3.1.3.41 ko:K00860,ko:K01101 ko00230,ko00627,ko00920,ko01100,ko01120,map00230,map00627,map00920,map01100,map01120 M00176 R00509,R03024,R04928 RC00002,RC00078,RC00151 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQGM@1239,3F49D@33958,4HA3R@91061,COG0647@1,COG0647@2 NA|NA|NA G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro GHBLAFEN_01735 405566.lhv_0461 1.7e-87 328.9 Lactobacillaceae yutD Bacteria 1VA85@1239,3F66P@33958,4HKF7@91061,COG4470@1,COG4470@2 NA|NA|NA S Protein of unknown function (DUF1027) GHBLAFEN_01736 405566.lhv_0460 6.2e-276 956.1 Lactobacillaceae yunD 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPV2@1239,3FC1D@33958,4H9VJ@91061,COG0737@1,COG0737@2 NA|NA|NA F Belongs to the 5'-nucleotidase family GHBLAFEN_01737 405566.lhv_0459 1.5e-55 221.9 Lactobacillaceae Bacteria 1VX4A@1239,2C26E@1,3424N@2,3F70Q@33958,4HXT9@91061 NA|NA|NA GHBLAFEN_01738 405566.lhv_0458 5.9e-255 886.3 Lactobacillaceae ugpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1V3W4@1239,3F4E3@33958,4HFNQ@91061,COG0584@1,COG0584@2 NA|NA|NA C glycerophosphoryl diester phosphodiesterase GHBLAFEN_01739 405566.lhv_0457 1.1e-178 632.5 Lactobacillaceae ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02529 ko00000,ko03000 Bacteria 1TQ7K@1239,3F4AA@33958,4H9NG@91061,COG1609@1,COG1609@2 NA|NA|NA K catabolite control protein A GHBLAFEN_01740 326425.lhe_1650 2.2e-215 754.6 Lactobacillaceae pepQ 3.4.13.9 ko:K01271 ko00000,ko01000,ko01002 Bacteria 1TQ6R@1239,3F3X5@33958,4HA5I@91061,COG0006@1,COG0006@2 NA|NA|NA E Creatinase/Prolidase N-terminal domain GHBLAFEN_01741 1423767.BALU01000013_gene123 2.6e-43 181.4 Lactobacillaceae Bacteria 1U63A@1239,29P3Z@1,30A26@2,3F6XS@33958,4IFSN@91061 NA|NA|NA GHBLAFEN_01742 1423748.BALB01000002_gene199 3.3e-10 71.6 Lactobacillaceae WQ51_05790 Bacteria 1VAXN@1239,3F6KB@33958,4HM93@91061,COG4768@1,COG4768@2 NA|NA|NA S protein containing a divergent version of the methyl-accepting chemotaxis-like domain GHBLAFEN_01743 405566.lhv_0453 2.3e-148 531.6 Lactobacillaceae ykuT GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0042802,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 ko:K22044 ko00000,ko02000 1.A.23.3 Bacteria 1TR9Z@1239,3F49U@33958,4HCB8@91061,COG0668@1,COG0668@2 NA|NA|NA M mechanosensitive ion channel GHBLAFEN_01744 326425.lhe_1654 7.1e-115 419.9 Lactobacillaceae rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 1V6RN@1239,3F3KD@33958,4HCP6@91061,COG0127@1,COG0127@2 NA|NA|NA F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions GHBLAFEN_01745 326425.lhe_1655 4.5e-146 523.9 Lactobacillaceae murI GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 iYO844.BSU28390 Bacteria 1TPPR@1239,3F446@33958,4HA46@91061,COG0796@1,COG0796@2 NA|NA|NA M Provides the (R)-glutamate required for cell wall biosynthesis GHBLAFEN_01746 1423748.BALB01000002_gene203 8.5e-69 266.2 Lactobacillaceae yslB Bacteria 1VD7N@1239,3F7ZI@33958,4HKV3@91061,COG1719@1,COG1719@2 NA|NA|NA S Protein of unknown function (DUF2507) GHBLAFEN_01747 326425.lhe_1657 8.4e-39 166.4 Lactobacillaceae mscL GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 ko:K03282 ko00000,ko02000 1.A.22.1 Bacteria 1VA14@1239,3F6YZ@33958,4HKIA@91061,COG1970@1,COG1970@2 NA|NA|NA M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell GHBLAFEN_01748 1423748.BALB01000002_gene205 4.6e-54 216.9 Lactobacillaceae trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1VA3Y@1239,3F6Y3@33958,4HKKX@91061,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family GHBLAFEN_01749 326425.lhe_1659 0.0 1305.0 Lactobacillaceae mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TP5W@1239,3F4DX@33958,4H9NZ@91061,COG1193@1,COG1193@2 NA|NA|NA L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity GHBLAFEN_01750 326425.lhe_1660 1.4e-50 205.3 Lactobacillaceae yrzB Bacteria 1VAPW@1239,3F6X3@33958,4HKV7@91061,COG3906@1,COG3906@2 NA|NA|NA S Belongs to the UPF0473 family GHBLAFEN_01751 1423748.BALB01000002_gene208 1e-72 279.3 Lactobacillaceae yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07447 ko00000,ko01000 Bacteria 1V6ER@1239,3F6NI@33958,4HH04@91061,COG0816@1,COG0816@2 NA|NA|NA J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA GHBLAFEN_01752 1033837.WANG_0122 9.7e-42 175.6 Lactobacillaceae yrzL Bacteria 1VAC4@1239,3F7EG@33958,4HKD0@91061,COG4472@1,COG4472@2 NA|NA|NA S Belongs to the UPF0297 family GHBLAFEN_01753 405566.lhv_0438 0.0 1741.5 Lactobacillaceae alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPK6@1239,3F3QS@33958,4H9XC@91061,COG0013@1,COG0013@2 NA|NA|NA J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain GHBLAFEN_01754 405566.lhv_0437 1.6e-51 208.4 Lactobacillaceae Bacteria 1VG2M@1239,2ERDT@1,33IZD@2,3F8CY@33958,4IGIT@91061 NA|NA|NA GHBLAFEN_01755 97137.C821_01309 2.9e-62 244.6 Lactobacillaceae Bacteria 1U7TP@1239,29QBD@1,30BAK@2,3FA5W@33958,4IHR5@91061 NA|NA|NA GHBLAFEN_01756 405566.lhv_0435 4.4e-226 790.4 Lactobacillaceae cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TPAP@1239,3F4FQ@33958,4HA98@91061,COG0513@1,COG0513@2 NA|NA|NA JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures GHBLAFEN_01757 326425.lhe_1665 3e-181 641.0 Lactobacillaceae nrnA GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPXX@1239,3F4FC@33958,4H9ZW@91061,COG0618@1,COG0618@2 NA|NA|NA S DHHA1 domain protein GHBLAFEN_01758 326425.lhe_1666 1.3e-210 738.8 Lactobacillaceae dinB GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031668,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 ko:K02346 ko00000,ko01000,ko03400 Bacteria 1TP42@1239,3F44N@33958,4HADJ@91061,COG0389@1,COG0389@2 NA|NA|NA L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII GHBLAFEN_01759 405566.lhv_0432 8.4e-284 982.2 Lactobacillaceae zwf GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 iIT341.HP1101 Bacteria 1TPYF@1239,3F48G@33958,4HA73@91061,COG0364@1,COG0364@2 NA|NA|NA G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone GHBLAFEN_01760 405566.lhv_0431 2.9e-35 154.8 Lactobacillaceae yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VEMC@1239,3F7EY@33958,4HNK0@91061,COG1862@1,COG1862@2 NA|NA|NA U Preprotein translocase GHBLAFEN_01761 405566.lhv_0430 2.8e-185 654.4 Lactobacillaceae ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TR47@1239,3F47S@33958,4HBMW@91061,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing GHBLAFEN_01762 1423748.BALB01000002_gene217 4.6e-103 380.6 Lactobacillaceae ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1V3KF@1239,3F42W@33958,4HHI5@91061,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB GHBLAFEN_01763 326425.lhe_1671 0.0 1217.2 Lactobacillaceae mutL GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TPGK@1239,3F3PK@33958,4HB34@91061,COG0323@1,COG0323@2 NA|NA|NA L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex GHBLAFEN_01764 326425.lhe_1672 0.0 1676.8 Lactobacillaceae mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TPRJ@1239,3F4A5@33958,4HA63@91061,COG0249@1,COG0249@2 NA|NA|NA L that it carries out the mismatch recognition step. This protein has a weak ATPase activity GHBLAFEN_01765 1033837.WANG_0111 4.2e-48 197.2 Lactobacillaceae Bacteria 1VIEC@1239,2EC9R@1,33683@2,3F7A0@33958,4HSN3@91061 NA|NA|NA GHBLAFEN_01766 525365.HMPREF0548_2171 2e-152 545.0 Lactobacillaceae levD ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276,M00304 R02630,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.2 Bacteria 1UNST@1239,3F5DT@33958,4HEX7@91061,COG3716@1,COG3716@2 NA|NA|NA G PTS system mannose/fructose/sorbose family IID component GHBLAFEN_01767 1033837.WANG_0109 4e-140 504.2 Lactobacillaceae ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1U8TN@1239,3F4QF@33958,4HE9V@91061,COG3715@1,COG3715@2 NA|NA|NA M PTS system sorbose-specific iic component GHBLAFEN_01768 1033837.WANG_0108 6.9e-92 343.2 Lactobacillaceae 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1UZRR@1239,3F593@33958,4HGGX@91061,COG3444@1,COG3444@2 NA|NA|NA G PTS system sorbose subfamily IIB component GHBLAFEN_01769 525365.HMPREF0548_2168 3.6e-68 264.2 Lactobacillaceae levA ko:K02744 ko00052,ko02060,map00052,map02060 M00277,M00287 R08366,R08367 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1.4,4.A.6.1.5 Bacteria 1V91U@1239,3FBI4@33958,4HN88@91061,COG2893@1,COG2893@2 NA|NA|NA G PTS system fructose IIA component GHBLAFEN_01770 1033837.WANG_0105 7.3e-106 390.6 Lactobacillaceae rbsB ko:K10439,ko:K10543 ko02010,ko02030,map02010,map02030 M00212,M00215 ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.4 Bacteria 1TQ1B@1239,3F4SC@33958,4HCV8@91061,COG1879@1,COG1879@2 NA|NA|NA G Periplasmic binding protein domain GHBLAFEN_01771 1033837.WANG_0104 1.4e-192 679.1 Lactobacillaceae baeS Bacteria 1TQI3@1239,3F3XQ@33958,4HAUU@91061,COG4585@1,COG4585@2 NA|NA|NA F Sensor histidine kinase GHBLAFEN_01772 525365.HMPREF0548_2164 1.4e-105 389.0 Lactobacillaceae baeR Bacteria 1TQ1U@1239,3F4DN@33958,4HA4B@91061,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon GHBLAFEN_01773 1033837.WANG_0102 6.3e-190 670.2 Lactobacillaceae ko:K02027 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 1TPX9@1239,3F579@33958,4HI13@91061,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein GHBLAFEN_01774 405566.lhv_0426 9.4e-292 1008.8 Lactobacillaceae groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 1TP1T@1239,3F3MM@33958,4HA38@91061,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions GHBLAFEN_01775 1423748.BALB01000002_gene222 3e-44 184.1 Lactobacillaceae groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0032991,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:0101031,GO:1903506,GO:1990220,GO:2000112,GO:2001141 ko:K04078 ko00000,ko03029,ko03110 Bacteria 1V9ZM@1239,3F7CZ@33958,4HKEK@91061,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter GHBLAFEN_01776 405566.lhv_0423 7.4e-89 333.2 Lactobacillaceae Bacteria 1U5M7@1239,2CHFM@1,301I5@2,3F66G@33958,4IFC0@91061 NA|NA|NA GHBLAFEN_01777 326425.lhe_1681 3.9e-47 193.7 Lactobacillaceae Bacteria 1UPY3@1239,2DN64@1,32VRU@2,3FC0U@33958,4IVD5@91061 NA|NA|NA GHBLAFEN_01778 1423748.BALB01000002_gene226 0.0 1198.3 Lactobacillaceae scrA 2.7.1.211,5.3.1.1 ko:K01803,ko:K02808,ko:K02809,ko:K02810 ko00010,ko00051,ko00500,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko02060,map00010,map00051,map00500,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map02060 M00001,M00002,M00003,M00269 R00811,R01015 RC00017,RC00423,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko04147 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system GHBLAFEN_01779 1033837.WANG_0093 3.2e-230 804.3 Lactobacillaceae scrB 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 GH32 Bacteria 1TPAE@1239,3F4UD@33958,4H9Y7@91061,COG1621@1,COG1621@2 NA|NA|NA G invertase GHBLAFEN_01780 1423748.BALB01000002_gene229 3.1e-181 641.0 Lactobacillaceae scrR ko:K02529,ko:K03484 ko00000,ko03000 Bacteria 1TQ7K@1239,3F4JE@33958,4H9V1@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family GHBLAFEN_01781 326425.lhe_1684 2.5e-122 444.9 Lactobacillaceae liaI ko:K11619 ko02020,map02020 M00754 ko00000,ko00001,ko00002 Bacteria 1V7WJ@1239,3F6JJ@33958,4HR21@91061,COG4758@1,COG4758@2 NA|NA|NA S membrane GHBLAFEN_01782 405566.lhv_0417 9.6e-77 292.7 Lactobacillaceae XK27_02470 Bacteria 1VBF7@1239,3F7K4@33958,4IPQI@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain GHBLAFEN_01783 405566.lhv_0416 5.7e-116 423.7 Lactobacillaceae rex ko:K01926 ko00000,ko03000 Bacteria 1TSMR@1239,3F40G@33958,4HB7Q@91061,COG2344@1,COG2344@2 NA|NA|NA K Modulates transcription in response to changes in cellular NADH NAD( ) redox state GHBLAFEN_01784 326425.lhe_1687 0.0 1100.9 Lactobacillaceae uup ko:K06158 ko00000,ko03012 Bacteria 1TPAX@1239,3F3QI@33958,4HBVV@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein GHBLAFEN_01785 891391.LAC30SC_01960 1.4e-12 77.8 Lactobacillaceae oxc GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0008150,GO:0008152,GO:0008949,GO:0009056,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019752,GO:0019842,GO:0030554,GO:0030976,GO:0032553,GO:0032555,GO:0032559,GO:0033609,GO:0033611,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043531,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046872,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0071704,GO:0097159,GO:0097367,GO:0104004,GO:1901265,GO:1901363,GO:1901575,GO:1901681 4.1.1.8 ko:K01577 ko00630,ko01100,map00630,map01100 R01908 RC00620 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_2523,iNJ661.Rv0118c Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family GHBLAFEN_01786 525365.HMPREF0548_2147 1.4e-216 758.8 Lactobacillaceae oxc GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0008150,GO:0008152,GO:0008949,GO:0009056,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019752,GO:0019842,GO:0030554,GO:0030976,GO:0032553,GO:0032555,GO:0032559,GO:0033609,GO:0033611,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043531,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046872,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0071704,GO:0097159,GO:0097367,GO:0104004,GO:1901265,GO:1901363,GO:1901575,GO:1901681 4.1.1.8 ko:K01577 ko00630,ko01100,map00630,map01100 R01908 RC00620 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_2523,iNJ661.Rv0118c Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family GHBLAFEN_01787 525365.HMPREF0548_2147 8.6e-38 162.5 Lactobacillaceae oxc GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0008150,GO:0008152,GO:0008949,GO:0009056,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019752,GO:0019842,GO:0030554,GO:0030976,GO:0032553,GO:0032555,GO:0032559,GO:0033609,GO:0033611,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043531,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046872,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0071704,GO:0097159,GO:0097367,GO:0104004,GO:1901265,GO:1901363,GO:1901575,GO:1901681 4.1.1.8 ko:K01577 ko00630,ko01100,map00630,map01100 R01908 RC00620 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_2523,iNJ661.Rv0118c Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family GHBLAFEN_01788 891391.LAC30SC_01955 1.1e-113 416.4 Lactobacillaceae frc GO:0003674,GO:0003824,GO:0008150,GO:0008410,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016740,GO:0016782,GO:0033608,GO:0050896,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0104004 2.8.3.16,2.8.3.19 ko:K07749,ko:K18702 ko00000,ko01000 iUMNK88_1353.UMNK88_2972 Bacteria 1TP54@1239,3F4GS@33958,4HABI@91061,COG1804@1,COG1804@2 NA|NA|NA C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate GHBLAFEN_01789 326425.lhe_1690 2.6e-107 394.8 Lactobacillaceae yfdE GO:0003674,GO:0003824,GO:0008410,GO:0016740,GO:0016782,GO:0036412 2.8.3.19 ko:K18702 ko00000,ko01000 Bacteria 1TP54@1239,3F4GS@33958,4HABI@91061,COG1804@1,COG1804@2 NA|NA|NA C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate GHBLAFEN_01790 326425.lhe_1690 3.7e-111 407.5 Lactobacillaceae yfdE GO:0003674,GO:0003824,GO:0008410,GO:0016740,GO:0016782,GO:0036412 2.8.3.19 ko:K18702 ko00000,ko01000 Bacteria 1TP54@1239,3F4GS@33958,4HABI@91061,COG1804@1,COG1804@2 NA|NA|NA C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate GHBLAFEN_01791 575606.HMPREF0525_00325 3.5e-27 128.3 Firmicutes ko:K19167 ko00000,ko02048 Bacteria 1VFXU@1239,2EAJ6@1,334N3@2 NA|NA|NA S Toxin ToxN, type III toxin-antitoxin system GHBLAFEN_01792 326425.lhe_1691 2e-129 468.4 Lactobacillaceae ko:K03710 ko00000,ko03000 Bacteria 1TVMZ@1239,3F66Q@33958,4H9TD@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA GHBLAFEN_01793 326425.lhe_1692 1.4e-181 642.1 Lactobacillaceae ko:K22230 ko00562,ko01120,map00562,map01120 R09954 RC00182 ko00000,ko00001,ko01000 Bacteria 1TQSS@1239,3F4U8@33958,4HV6B@91061,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold GHBLAFEN_01794 1423748.BALB01000002_gene238 2.8e-123 448.0 Lactobacillaceae deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 ko:K01619 ko00030,map00030 R01066 RC00436,RC00437 ko00000,ko00001,ko01000 Bacteria 1TPAJ@1239,3FCCC@33958,4HF5U@91061,COG0274@1,COG0274@2 NA|NA|NA F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate GHBLAFEN_01795 405566.lhv_1767 1.1e-103 382.5 Lactobacillaceae Bacteria 1VB88@1239,3F5AR@33958,4IPQF@91061,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase GHBLAFEN_01796 326425.lhe_0455 3.9e-170 604.0 Lactobacillaceae coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECDH1ME8569_1439.ECDH1ME8569_3838,iECH74115_1262.ECH74115_5439,iECSE_1348.ECSE_4265,iECSF_1327.ECSF_3833,iECSP_1301.ECSP_5045,iECW_1372.ECW_m4332,iEcDH1_1363.EcDH1_4016,iEcolC_1368.EcolC_4046,iPC815.YPO3758,iSFV_1184.SFV_4047,iSFxv_1172.SFxv_4418,iWFL_1372.ECW_m4332,iZ_1308.Z5545 Bacteria 1TPHJ@1239,3F42Q@33958,4HA4K@91061,COG1072@1,COG1072@2 NA|NA|NA F Pantothenic acid kinase GHBLAFEN_01797 1423748.BALB01000015_gene1378 1.3e-102 379.0 Lactobacillaceae efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 1TR8P@1239,3F4EW@33958,4H9YX@91061,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase GHBLAFEN_01798 405566.lhv_1764 3.1e-245 854.0 Lactobacillaceae ko:K02027,ko:K05813 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 Bacteria 1TS64@1239,3F4P5@33958,4HEKH@91061,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein GHBLAFEN_01799 326425.lhe_0458 1.4e-66 258.8 Lactobacillaceae Bacteria 1U5TJ@1239,3F6H2@33958,4IFHH@91061,COG3212@1,COG3212@2 NA|NA|NA S Peptidase propeptide and YPEB domain GHBLAFEN_01800 1423748.BALB01000015_gene1375 7.8e-14 82.4 Lactobacillaceae Bacteria 1U5TJ@1239,3F6H2@33958,4IFHH@91061,COG3212@1,COG3212@2 NA|NA|NA S Peptidase propeptide and YPEB domain GHBLAFEN_01801 1423748.BALB01000015_gene1374 1.4e-67 262.3 Lactobacillaceae yybA 2.3.1.57 ko:K22441 ko00000,ko01000 Bacteria 1V3PS@1239,3F6VT@33958,4HFN6@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator GHBLAFEN_01802 1423748.BALB01000015_gene1373 5.8e-86 323.6 Lactobacillaceae paiA 2.3.1.57 ko:K22441 ko00000,ko01000 Bacteria 1VDFK@1239,3FB81@33958,4HMHW@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain GHBLAFEN_01803 1423748.BALB01000015_gene1372 2.7e-69 268.5 Lactobacillaceae Bacteria 1VD0Q@1239,3FBE6@33958,4IPQG@91061,COG3212@1,COG3212@2 NA|NA|NA S Peptidase propeptide and YPEB domain GHBLAFEN_01804 326425.lhe_0459 2.5e-94 351.3 Lactobacillaceae Bacteria 1V8XI@1239,3FBAU@33958,4HJ7M@91061,COG3613@1,COG3613@2 NA|NA|NA F Nucleoside 2-deoxyribosyltransferase GHBLAFEN_01805 405566.lhv_1760 5.1e-187 660.2 Lactobacillaceae add 3.5.4.4 ko:K01488 ko00230,ko01100,ko05340,map00230,map01100,map05340 R01560,R02556 RC00477 ko00000,ko00001,ko01000 iHN637.CLJU_RS13960 Bacteria 1U44B@1239,3F5RC@33958,4HCES@91061,COG1816@1,COG1816@2 NA|NA|NA F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism GHBLAFEN_01806 1423748.BALB01000015_gene1369 9.3e-180 636.0 Lactobacillaceae pip 3.4.11.5 ko:K01259 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 1UEDT@1239,3F47H@33958,4HF61@91061,COG2267@1,COG2267@2 NA|NA|NA E Releases the N-terminal proline from various substrates GHBLAFEN_01807 405566.lhv_1758 1.9e-276 958.0 Lactobacillaceae ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TSRV@1239,3F3JJ@33958,4HIAU@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region GHBLAFEN_01808 1423748.BALB01000022_gene1697 2.2e-17 94.0 Lactobacillaceae 2.4.2.6 ko:K08728 ko00240,map00240 R02806 RC00063 ko00000,ko00001,ko01000 Bacteria 1V8XI@1239,3FBAU@33958,4HJ7M@91061,COG3613@1,COG3613@2 NA|NA|NA F Nucleoside 2-deoxyribosyltransferase GHBLAFEN_01809 1423748.BALB01000022_gene1698 9.4e-179 632.9 Lactobacillaceae tcsA ko:K02058,ko:K07335 M00221 ko00000,ko00002,ko02000 3.A.1.2 Bacteria 1TPEU@1239,3F3MZ@33958,4HANH@91061,COG1744@1,COG1744@2 NA|NA|NA S ABC transporter substrate-binding protein PnrA-like GHBLAFEN_01810 405566.lhv_1516 2.3e-247 861.3 Lactobacillaceae xylG 3.6.3.17 ko:K02056,ko:K06400 M00221 ko00000,ko00002,ko01000,ko02000 3.A.1.2 Bacteria 1UYQA@1239,3F50N@33958,4HVSH@91061,COG3845@1,COG3845@2 NA|NA|NA S ABC transporter GHBLAFEN_01811 1423748.BALB01000022_gene1701 1.7e-167 595.5 Lactobacillaceae yufP GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 ko:K02057 M00221 ko00000,ko00002,ko02000 3.A.1.2 Bacteria 1TP1F@1239,3F59X@33958,4H9VE@91061,COG4603@1,COG4603@2 NA|NA|NA S Belongs to the binding-protein-dependent transport system permease family GHBLAFEN_01812 1423748.BALB01000022_gene1702 2e-161 575.1 Lactobacillaceae yufQ ko:K02057 M00221 ko00000,ko00002,ko02000 3.A.1.2 Bacteria 1TP8Y@1239,3F4AJ@33958,4HAX4@91061,COG1079@1,COG1079@2 NA|NA|NA S Belongs to the binding-protein-dependent transport system permease family GHBLAFEN_01813 326425.lhe_1371 0.0 1598.2 Lactobacillaceae 3.6.3.8 ko:K01537 ko00000,ko01000 3.A.3.2 Bacteria 1TPF5@1239,3F3KP@33958,4H9S5@91061,COG0474@1,COG0474@2 NA|NA|NA P P-type ATPase GHBLAFEN_01814 525365.HMPREF0548_0217 5.8e-212 743.4 Lactobacillaceae clcA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006821,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015672,GO:0015698,GO:0015706,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0031404,GO:0034220,GO:0042802,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 ko:K03281 ko00000 2.A.49 iAF1260.b0155,iB21_1397.B21_00153,iBWG_1329.BWG_0148,iE2348C_1286.E2348C_0162,iEC042_1314.EC042_0155,iEC55989_1330.EC55989_0149,iECBD_1354.ECBD_3463,iECDH10B_1368.ECDH10B_0135,iECDH1ME8569_1439.ECDH1ME8569_0149,iECD_1391.ECD_00154,iECIAI1_1343.ECIAI1_0153,iECO103_1326.ECO103_0155,iECSE_1348.ECSE_0156,iECUMN_1333.ECUMN_0152,iECW_1372.ECW_m0152,iEKO11_1354.EKO11_3761,iETEC_1333.ETEC_0151,iEcDH1_1363.EcDH1_3447,iEcE24377_1341.EcE24377A_0160,iEcolC_1368.EcolC_3504,iJO1366.b0155,iSSON_1240.SSON_0167,iUMNK88_1353.UMNK88_159,iWFL_1372.ECW_m0152,iY75_1357.Y75_RS00790,iZ_1308.Z0166 Bacteria 1TPX0@1239,3F587@33958,4HD2H@91061,COG0038@1,COG0038@2 NA|NA|NA P chloride GHBLAFEN_01815 525365.HMPREF0548_0219 3.3e-39 167.2 Lactobacillaceae XK27_08875 Bacteria 1U6CU@1239,3F7MF@33958,4IG4J@91061,COG5549@1,COG5549@2 NA|NA|NA O Matrixin GHBLAFEN_01816 525365.HMPREF0548_0220 1.8e-46 191.4 Firmicutes Bacteria 1VC64@1239,29PJD@1,30AHI@2 NA|NA|NA S Domain of unknown function (DUF4160) GHBLAFEN_01817 405566.lhv_1463 2.9e-50 204.5 Lactobacillaceae Bacteria 1U7SC@1239,29QAG@1,30B9M@2,3FA3U@33958,4IHPQ@91061 NA|NA|NA GHBLAFEN_01819 1116231.SMA_p0014 4.7e-58 230.3 Bacilli mobC Bacteria 1VF06@1239,2E4NU@1,32ZHN@2,4HPMK@91061 NA|NA|NA S Bacterial mobilisation protein (MobC) GHBLAFEN_01820 1229517.AMFD01000011_gene565 3.2e-199 701.0 Lactococcus ko:K02557,ko:K18376 ko02030,ko02040,map02030,map02040 M00660 ko00000,ko00001,ko00002,ko02000,ko02035,ko02044 1.A.30.1,1.C.65.1 Bacteria 1TVSM@1239,1YC6P@1357,4I428@91061,COG1196@1,COG1196@2 NA|NA|NA D Relaxase/Mobilisation nuclease domain GHBLAFEN_01821 1215915.BN193_11505 3.4e-109 401.0 Lactococcus Bacteria 1U3AK@1239,1YC4S@1357,2BUV6@1,32Q6Z@2,4ID2K@91061 NA|NA|NA GHBLAFEN_01822 1215915.BN193_11500 5.8e-62 243.4 Lactococcus XK27_09990 ko:K04095 ko00000,ko03036 Bacteria 1TPUZ@1239,1YC7U@1357,4I3M2@91061,COG2184@1,COG2184@2 NA|NA|NA D Fic/DOC family GHBLAFEN_01824 272626.pli0023 4.3e-182 644.0 Bacilli ko:K07498 ko00000 Bacteria 1V1XJ@1239,4HD1W@91061,COG5527@1,COG5527@2 NA|NA|NA L Lactococcus lactis RepB C-terminus GHBLAFEN_01826 1117379.BABA_13090 1.2e-39 168.7 Bacillus 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1TP5N@1239,1ZRN5@1386,4IQS7@91061,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain GHBLAFEN_01827 1229758.C270_03955 1.3e-98 366.3 Leuconostocaceae 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1TP5N@1239,4AXBM@81850,4HFAV@91061,COG0732@1,COG0732@2 NA|NA|NA V type I restriction modification DNA specificity domain protein GHBLAFEN_01828 1400520.LFAB_17430 1.7e-38 164.9 Lactobacillaceae Bacteria 1U63Q@1239,2DKNJ@1,30A2H@2,3F6YR@33958,4IFT5@91061 NA|NA|NA S Antitoxin component of a toxin-antitoxin (TA) module GHBLAFEN_01829 1133569.AHYZ01000091_gene709 7e-104 383.3 Lactobacillaceae ko:K04763 ko00000,ko03036 Bacteria 1V2RX@1239,3F4SP@33958,4IEJ7@91061,COG0582@1,COG0582@2 NA|NA|NA L Integrase GHBLAFEN_01832 405566.lhv_1255 0.0 1111.7 Lactobacillaceae FbpA ko:K12341 ko03070,map03070 ko00000,ko00001,ko02044 1.B.40.1.1 Bacteria 1TQ8A@1239,3F3PS@33958,4H9UF@91061,COG1293@1,COG1293@2 NA|NA|NA K Fibronectin-binding protein GHBLAFEN_01833 326425.lhe_1135 7.7e-65 253.1 Lactobacillaceae Bacteria 1U6A0@1239,29P8Y@1,30A72@2,3F7ER@33958,4IG18@91061 NA|NA|NA GHBLAFEN_01834 405566.lhv_1254 1.8e-159 568.5 Lactobacillaceae degV Bacteria 1TRM7@1239,3F40W@33958,4HBIR@91061,COG1307@1,COG1307@2 NA|NA|NA S EDD domain protein, DegV family GHBLAFEN_01835 326425.lhe_1133 7.6e-205 719.5 Lactobacillaceae xerS GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 ko:K04763 ko00000,ko03036 Bacteria 1TPQB@1239,3F3P9@33958,4HANE@91061,COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family GHBLAFEN_01836 1423748.BALB01000007_gene904 5.3e-67 260.4 Lactobacillaceae Bacteria 1U5N3@1239,29EME@1,301JC@2,3F67R@33958,4IFCU@91061 NA|NA|NA GHBLAFEN_01837 405566.lhv_2517 5.9e-88 330.1 Lactobacillaceae adk 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1V7AW@1239,3F6PA@33958,4HH8A@91061,COG0563@1,COG0563@2 NA|NA|NA F topology modulation protein GHBLAFEN_01838 405566.lhv_1249 1.2e-109 402.5 Lactobacillaceae XK27_00160 Bacteria 1V5Q4@1239,29N5D@1,30939@2,3F5S8@33958,4HHUF@91061 NA|NA|NA S Domain of unknown function (DUF5052) GHBLAFEN_01839 405566.lhv_2516 1.3e-52 212.2 Lactobacillaceae Bacteria 1TV1H@1239,2DINK@1,303QK@2,3F7U7@33958,4HYBN@91061 NA|NA|NA GHBLAFEN_01840 1423748.BALB01000007_gene907 8.2e-28 129.0 Lactobacillaceae ko:K07273 ko00000 Bacteria 1VF8D@1239,3F4U9@33958,4HX0U@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 GHBLAFEN_01841 1423748.BALB01000007_gene907 3.2e-91 341.3 Lactobacillaceae ko:K07273 ko00000 Bacteria 1VF8D@1239,3F4U9@33958,4HX0U@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 GHBLAFEN_01842 1423748.BALB01000007_gene907 2.9e-17 94.4 Lactobacillaceae ko:K07273 ko00000 Bacteria 1VF8D@1239,3F4U9@33958,4HX0U@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 GHBLAFEN_01843 1423748.BALB01000007_gene908 1.5e-34 151.8 Lactobacillaceae Bacteria 1VENK@1239,3F7EK@33958,4HNKV@91061,COG2261@1,COG2261@2 NA|NA|NA S Transglycosylase associated protein GHBLAFEN_01844 326425.lhe_0652 3.2e-305 1053.5 Lactobacillaceae prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02837,ko:K07133 ko00000,ko03012 Bacteria 1TPYT@1239,3F489@33958,4HADS@91061,COG4108@1,COG4108@2 NA|NA|NA J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP GHBLAFEN_01845 326425.lhe_0651 1.3e-159 568.9 Lactobacillaceae hlyX ko:K03699 ko00000,ko02042 Bacteria 1TPN0@1239,3F3KG@33958,4H9SB@91061,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain GHBLAFEN_01846 326425.lhe_0650 1.3e-73 282.3 Lactobacillaceae Bacteria 1U5U1@1239,2C070@1,300GJ@2,3F6I5@33958,4IFHZ@91061 NA|NA|NA GHBLAFEN_01847 326425.lhe_0649 1.9e-86 325.1 Lactobacillaceae Bacteria 1U5P0@1239,29NVN@1,309TR@2,3F693@33958,4IFDJ@91061 NA|NA|NA GHBLAFEN_01848 405566.lhv_0678 9.6e-144 516.2 Lactobacillaceae recX GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496 2.4.1.337 ko:K03565,ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003,ko03400 GT4 Bacteria 1V72V@1239,3F4BY@33958,4HJ7R@91061,COG2137@1,COG2137@2 NA|NA|NA S Regulatory protein RecX GHBLAFEN_01849 326425.lhe_0647 3.3e-261 907.1 Lactobacillaceae rumA 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 ko00000,ko01000,ko03009,ko03016 Bacteria 1TP4H@1239,3F4GQ@33958,4HA6M@91061,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family GHBLAFEN_01850 1423748.BALB01000004_gene601 2.8e-98 364.8 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TQYU@1239,3F43H@33958,4HC4H@91061,COG1073@1,COG1073@2 NA|NA|NA D Alpha beta GHBLAFEN_01854 326425.lhe_0081 3e-69 267.7 Lactobacillaceae def 3.5.1.31,3.5.1.88 ko:K01450,ko:K01462 ko00270,ko00630,map00270,map00630 R00653 RC00165,RC00323 ko00000,ko00001,ko01000 Bacteria 1V73T@1239,3F6ZA@33958,4HISW@91061,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins GHBLAFEN_01855 326425.lhe_0078 4.3e-194 683.7 Lactobacillaceae pbpX1 Bacteria 1V4BS@1239,3F3QN@33958,4HJRT@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase GHBLAFEN_01856 326425.lhe_0077 0.0 1882.5 Lactobacillaceae Bacteria 1TQ62@1239,3F3YQ@33958,4HAJ1@91061,COG1061@1,COG1061@2,COG3886@1,COG3886@2 NA|NA|NA L Helicase C-terminal domain protein GHBLAFEN_01857 1423748.BALB01000018_gene1516 3.1e-262 910.6 Lactobacillaceae ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1TRUM@1239,3F3Y1@33958,4HE3V@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid GHBLAFEN_01858 326425.lhe_0075 3.3e-160 570.9 Lactobacillaceae xth GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPFB@1239,3F4GK@33958,4HAIU@91061,COG0708@1,COG0708@2 NA|NA|NA L exodeoxyribonuclease III GHBLAFEN_01859 326425.lhe_0074 4.1e-92 344.0 Lactobacillaceae yniA GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 Bacteria 1U79A@1239,3F3RK@33958,4HAZS@91061,COG3001@1,COG3001@2 NA|NA|NA G Phosphotransferase enzyme family GHBLAFEN_01860 326425.lhe_0074 2.6e-67 261.2 Lactobacillaceae yniA GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 Bacteria 1U79A@1239,3F3RK@33958,4HAZS@91061,COG3001@1,COG3001@2 NA|NA|NA G Phosphotransferase enzyme family GHBLAFEN_01861 1033837.WANG_1627 3.4e-191 674.1 Lactobacillaceae ldhA 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3FB6C@33958,4HH0S@91061,COG1052@1,COG1052@2 NA|NA|NA C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family GHBLAFEN_01862 1033837.WANG_1626 3.3e-56 224.2 Lactobacillaceae Bacteria 1U60N@1239,29NJE@1,30RS9@2,3F6SP@33958,4IFPF@91061 NA|NA|NA GHBLAFEN_01864 1074451.CRL705_1859 0.0 1525.4 Lactobacillaceae uvrA2 Bacteria 1TR1H@1239,3F50Y@33958,4H9RE@91061,COG0178@1,COG0178@2 NA|NA|NA L ABC transporter GHBLAFEN_01865 203123.OEOE_0347 1.2e-103 382.5 Leuconostocaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,4AXYS@81850,4HC8M@91061,COG2801@1,COG2801@2 NA|NA|NA L HTH-like domain GHBLAFEN_01866 1123359.AUIQ01000085_gene536 9.5e-92 342.8 Enterococcaceae ko:K07483 ko00000 Bacteria 1V35U@1239,4B6SW@81852,4HHRN@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain GHBLAFEN_01867 1140001.I571_02837 2.4e-223 781.2 Enterococcaceae oxlT ko:K08177 ko00000,ko02000 2.A.1.11 Bacteria 1TPR9@1239,4AZGP@81852,4HB93@91061,COG2223@1,COG2223@2 NA|NA|NA P Major Facilitator Superfamily GHBLAFEN_01868 1033837.WANG_1782 3.3e-217 760.8 Lactobacillaceae yceI ko:K08369 ko00000,ko02000 2.A.1 Bacteria 1TQM0@1239,3F3SE@33958,4HATA@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GHBLAFEN_01869 1033837.WANG_1781 1.1e-153 549.3 Lactobacillaceae nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 1.4.3.16,2.4.2.19 ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481,R03348 RC00006,RC02566,RC02877 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1988,iHN637.CLJU_RS12010,iLJ478.TM1645 Bacteria 1TPQC@1239,3F58H@33958,4HB46@91061,COG0157@1,COG0157@2 NA|NA|NA H Quinolinate phosphoribosyl transferase, C-terminal domain GHBLAFEN_01870 326425.lhe_1603 5.1e-78 297.0 Lactobacillaceae smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 ko:K03664 ko00000 Bacteria 1V3IJ@1239,3F65B@33958,4HGZX@91061,COG0691@1,COG0691@2 NA|NA|NA J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA GHBLAFEN_01871 405566.lhv_0472 0.0 1495.7 Lactobacillaceae rnr ko:K12573,ko:K12585 ko03018,map03018 M00391 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 1TQ1G@1239,3F4EC@33958,4HBBH@91061,COG0557@1,COG0557@2 NA|NA|NA J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs GHBLAFEN_01872 326425.lhe_1605 2.3e-29 134.4 Lactobacillaceae secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VEQR@1239,3F7IQ@33958,4HNKC@91061,COG1314@1,COG1314@2 NA|NA|NA U Preprotein translocase GHBLAFEN_01873 405566.lhv_0470 0.0 1347.0 Lactobacillaceae ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 R05081,R10849 RC00017 ko00000,ko00001,ko01000 Bacteria 1TRMA@1239,3F3R7@33958,4H9S0@91061,COG1368@1,COG1368@2 NA|NA|NA M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily GHBLAFEN_01874 405566.lhv_0469 3.3e-178 630.9 Lactobacillaceae mprF ko:K07027 ko00000,ko02000 4.D.2 Bacteria 1TR9T@1239,3FBJD@33958,4IQVI@91061,COG0392@1,COG0392@2 NA|NA|NA S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms GHBLAFEN_01875 326425.lhe_1608 4.2e-200 703.7 Lactobacillaceae cpoA GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901576 ko:K13678 R10865 RC00005,RC00049 ko00000,ko01000,ko01003 GT4 Bacteria 1TPSS@1239,3F47X@33958,4HB9F@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase, group 1 family protein GHBLAFEN_01876 326425.lhe_1609 8.1e-221 772.7 Lactobacillaceae mgs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 GT4 Bacteria 1TPTA@1239,3FC1E@33958,4IPQK@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase 4-like domain GHBLAFEN_01883 1423748.BALB01000035_gene1973 1.8e-213 748.4 Lactobacillaceae mdtG GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085 ko:K08161 ko00000,ko02000 2.A.1.2.20 Bacteria 1TRDJ@1239,3F3T5@33958,4H9Q9@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GHBLAFEN_01884 405566.lhv_1888 5.7e-167 593.6 Lactobacillaceae Bacteria 1U59F@1239,29NN9@1,309K7@2,3F59C@33958,4IF0Q@91061 NA|NA|NA GHBLAFEN_01885 326425.lhe_0329 1.2e-58 232.3 Lactobacillaceae lysM Bacteria 1U5V5@1239,3F6J1@33958,4IFIT@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain GHBLAFEN_01887 405566.lhv_1886 0.0 1684.5 Lactobacillaceae pepN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 1TR43@1239,3F3UH@33958,4HA20@91061,COG0308@1,COG0308@2 NA|NA|NA E aminopeptidase GHBLAFEN_01888 1423748.BALB01000035_gene1980 1e-247 862.4 Lactobacillaceae dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03305 ko00000 2.A.17 Bacteria 1TP81@1239,3F4WU@33958,4HAF2@91061,COG3104@1,COG3104@2 NA|NA|NA U amino acid peptide transporter GHBLAFEN_01889 1423748.BALB01000035_gene1981 1.8e-24 117.9 Lactobacillaceae Bacteria 1U6RB@1239,29PKP@1,30AIV@2,3F8CU@33958,4IGIQ@91061 NA|NA|NA GHBLAFEN_01890 1423748.BALB01000035_gene1982 1.6e-182 645.6 Lactobacillaceae Bacteria 1TQMA@1239,3F3QW@33958,4HDTN@91061,COG1376@1,COG1376@2 NA|NA|NA S Putative peptidoglycan binding domain GHBLAFEN_01892 405566.lhv_0015 4.7e-111 407.1 Lactobacillaceae Bacteria 1U59E@1239,29DXA@1,300V7@2,3F59A@33958,4IF0P@91061 NA|NA|NA S SLAP domain GHBLAFEN_01893 326425.lhe_0018 0.0 1281.2 Lactobacillaceae yybT Bacteria 1TPGP@1239,3F3TY@33958,4HBVH@91061,COG3887@1,COG3887@2 NA|NA|NA T signaling protein consisting of a modified GGDEF domain and a DHH domain GHBLAFEN_01894 1423748.BALB01000029_gene1873 1.1e-67 262.7 Lactobacillaceae rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6QG@1239,3F68P@33958,4HIKJ@91061,COG0359@1,COG0359@2 NA|NA|NA J Binds to the 23S rRNA GHBLAFEN_01895 1423748.BALB01000029_gene1874 6.7e-254 882.9 Lactobacillaceae dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 1TPCT@1239,3F4MW@33958,4H9Y8@91061,COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication GHBLAFEN_01896 405566.lhv_0019 3.3e-164 584.3 Lactobacillaceae phnD ko:K02044 ko02010,map02010 M00223 ko00000,ko00001,ko00002,ko02000 3.A.1.9 Bacteria 1TR0H@1239,3FB6H@33958,4HBU5@91061,COG3221@1,COG3221@2 NA|NA|NA P ABC transporter, phosphonate, periplasmic substrate-binding protein GHBLAFEN_01897 405566.lhv_0021 4.1e-175 620.5 Lactobacillaceae degV Bacteria 1V289@1239,3F4D9@33958,4I3AR@91061,COG1307@1,COG1307@2 NA|NA|NA S DegV family GHBLAFEN_01898 326425.lhe_0025 1.4e-169 602.1 Lactobacillaceae scrK 2.7.1.2,2.7.1.4 ko:K00845,ko:K00847 ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R00760,R00867,R01600,R01786,R03920 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQU4@1239,3F3K8@33958,4HA1C@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family GHBLAFEN_01899 1423748.BALB01000004_gene503 4.8e-57 227.3 Lactobacillaceae pacL 3.6.3.8 ko:K01537 ko00000,ko01000 3.A.3.2 Bacteria 1TPF5@1239,3F3KP@33958,4H9S5@91061,COG0474@1,COG0474@2 NA|NA|NA P P-type ATPase GHBLAFEN_01900 1423748.BALB01000004_gene503 0.0 1325.8 Lactobacillaceae pacL 3.6.3.8 ko:K01537 ko00000,ko01000 3.A.3.2 Bacteria 1TPF5@1239,3F3KP@33958,4H9S5@91061,COG0474@1,COG0474@2 NA|NA|NA P P-type ATPase GHBLAFEN_01901 405566.lhv_0546 2.1e-224 784.6 Lactobacillaceae Bacteria 1VD8C@1239,3F52X@33958,4HI8C@91061,COG1887@1,COG1887@2 NA|NA|NA M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase GHBLAFEN_01902 326425.lhe_0541 2.4e-259 901.0 Lactobacillaceae epsU Bacteria 1TRTX@1239,3FB7P@33958,4HDWM@91061,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein GHBLAFEN_01903 405566.lhv_0548 1.7e-136 491.9 Lactobacillaceae Bacteria 1V9J7@1239,3F4U2@33958,4HIAM@91061,COG3774@1,COG3774@2 NA|NA|NA M Glycosyltransferase sugar-binding region containing DXD motif GHBLAFEN_01904 326425.lhe_0543 1.1e-86 325.9 Lactobacillaceae ydcK ko:K03095 ko00000 Bacteria 1V6NU@1239,3F703@33958,4HIHY@91061,COG3091@1,COG3091@2 NA|NA|NA S Belongs to the SprT family GHBLAFEN_01906 326425.lhe_0545 2e-104 385.2 Lactobacillaceae acmC 3.2.1.17,3.2.1.96 ko:K01185,ko:K01227,ko:K02395 ko00511,map00511 ko00000,ko00001,ko01000,ko02035 Bacteria 1V7JY@1239,3F584@33958,4HIY4@91061,COG1705@1,COG1705@2 NA|NA|NA NU mannosyl-glycoprotein GHBLAFEN_01907 405566.lhv_0550 0.0 1465.7 Lactobacillaceae pcrA 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPSU@1239,3F400@33958,4HB12@91061,COG0210@1,COG0210@2 NA|NA|NA L ATP-dependent DNA helicase GHBLAFEN_01908 326425.lhe_0547 0.0 1316.6 Lactobacillaceae ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1TPQ3@1239,3F43C@33958,4HA1D@91061,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA GHBLAFEN_01909 326425.lhe_0548 3e-207 727.6 Lactobacillaceae camS Bacteria 1TSYE@1239,3F3KI@33958,4HBI8@91061,COG4851@1,COG4851@2 NA|NA|NA S sex pheromone GHBLAFEN_01910 405566.lhv_0553 5.2e-50 203.4 Lactobacillaceae gatC 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 iAF987.Gmet_0076 Bacteria 1VEK3@1239,3F7XB@33958,4HNNA@91061,COG0721@1,COG0721@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) GHBLAFEN_01911 326425.lhe_0550 2.2e-260 904.4 Lactobacillaceae gatA 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 1TP0C@1239,3F4BK@33958,4HBAZ@91061,COG0154@1,COG0154@2 NA|NA|NA J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) GHBLAFEN_01912 405566.lhv_0555 8.3e-276 955.7 Lactobacillaceae gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 ko:K01876,ko:K02434 ko00970,ko01100,map00970,map01100 M00359,M00360 R03905,R04212,R05577 RC00010,RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPG3@1239,3F44H@33958,4HAFB@91061,COG0064@1,COG0064@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) GHBLAFEN_01913 326425.lhe_0552 3e-170 604.4 Lactobacillaceae yegS GO:0001727,GO:0003674,GO:0003824,GO:0004143,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0030258,GO:0044237,GO:0044238,GO:0044255,GO:0046834,GO:0071704 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 R02240 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TQAU@1239,3F447@33958,4H9WD@91061,COG1597@1,COG1597@2 NA|NA|NA G Lipid kinase GHBLAFEN_01914 1033837.WANG_1133 4.7e-115 420.6 Lactobacillaceae Bacteria 1VNI3@1239,3F5J9@33958,4HSHZ@91061,COG3548@1,COG3548@2 NA|NA|NA S Protein of unknown function (DUF1211) GHBLAFEN_01915 1033837.WANG_1132 1.1e-119 436.0 Lactobacillaceae ybhL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06890 ko00000 Bacteria 1V779@1239,3F3QH@33958,4HIX1@91061,COG0670@1,COG0670@2 NA|NA|NA S Belongs to the BI1 family GHBLAFEN_01916 1033837.WANG_1131 3.5e-55 220.7 Lactobacillaceae Bacteria 1UQJZ@1239,2BQGU@1,32JC9@2,3F6M4@33958,4IFJT@91061 NA|NA|NA GHBLAFEN_01917 1033837.WANG_1130 9.2e-248 862.4 Lactobacillaceae nhaC ko:K03315 ko00000,ko02000 2.A.35 Bacteria 1TQ3B@1239,3F3VX@33958,4HA18@91061,COG1757@1,COG1757@2 NA|NA|NA C Na H antiporter NhaC GHBLAFEN_01918 405566.lhv_0563 2.6e-255 887.5 Lactobacillaceae rumA GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 ko00000,ko01000,ko03009 Bacteria 1TP4H@1239,3F41R@33958,4HA6M@91061,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family GHBLAFEN_01919 1154757.Q5C_05365 9.3e-68 262.7 Leuconostocaceae Bacteria 1TRSF@1239,4AXKQ@81850,4HVB3@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives IS30 family GHBLAFEN_01921 326425.lhe_0634 5.3e-59 233.4 Lactobacillaceae ko:K10947 ko00000,ko03000 Bacteria 1VIVQ@1239,3FBMB@33958,4IR4R@91061,COG1695@1,COG1695@2 NA|NA|NA K transcriptional regulator PadR family GHBLAFEN_01922 326425.lhe_0633 2.2e-38 164.5 Bacilli ko:K03973 ko00000,ko02048,ko03000 Bacteria 1VKBQ@1239,4HRGW@91061,COG1983@1,COG1983@2 NA|NA|NA KT PspC domain protein GHBLAFEN_01923 405566.lhv_0574 3e-80 304.7 Lactobacillaceae ydhK Bacteria 1V3Q9@1239,3F7G7@33958,4HH9X@91061,COG1388@1,COG1388@2 NA|NA|NA M Protein of unknown function (DUF1541) GHBLAFEN_01924 543734.LCABL_01440 1.3e-121 442.6 Lactobacillaceae Bacteria 1TRSF@1239,3F4DZ@33958,4HCMP@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair GHBLAFEN_01925 1033837.WANG_1127 5.9e-227 793.1 Lactobacillaceae tnp2 Bacteria 1TQ93@1239,3F4RB@33958,4HC0Q@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM Transposase, IS204 IS1001 IS1096 IS1165 GHBLAFEN_01926 1033837.WANG_1126 1.6e-28 131.3 Lactobacillaceae cspA ko:K03704 ko00000,ko03000 Bacteria 1VEE0@1239,3F7FW@33958,4HNJC@91061,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein GHBLAFEN_01929 334390.LAF_1040 8.7e-116 422.9 Bacteria Bacteria COG0553@1,COG0553@2 NA|NA|NA L helicase activity GHBLAFEN_01930 1033837.WANG_1119 2.8e-61 241.1 Lactobacillaceae Bacteria 1U7RV@1239,29QA7@1,30B9B@2,3FA39@33958,4IHP7@91061 NA|NA|NA GHBLAFEN_01931 1033837.WANG_1118 2.1e-96 358.2 Lactobacillaceae MA20_25245 Bacteria 1VJPU@1239,3F5MH@33958,4HG6J@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain GHBLAFEN_01935 1033837.WANG_1117 1.6e-242 845.1 Lactobacillaceae emrY Bacteria 1VSW8@1239,3F4AW@33958,4HUQC@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GHBLAFEN_01936 1033837.WANG_1116 2.7e-91 341.3 Lactobacillaceae yxdD Bacteria 1VGCX@1239,3FC4I@33958,4HH8V@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family GHBLAFEN_01937 1423748.BALB01000004_gene527 2.3e-165 588.2 Lactobacillaceae 4.2.1.53 ko:K10254 ko00000,ko01000 Bacteria 1TQZ6@1239,3F3QX@33958,4HAYH@91061,COG4716@1,COG4716@2 NA|NA|NA S Myosin-crossreactive antigen GHBLAFEN_01938 525365.HMPREF0548_0581 9.4e-152 542.7 Lactobacillaceae 4.2.1.53 ko:K10254 ko00000,ko01000 Bacteria 1TQZ6@1239,3F9PU@33958,4HAYH@91061,COG4716@1,COG4716@2 NA|NA|NA S MCRA family GHBLAFEN_01939 525365.HMPREF0548_0582 9.9e-85 319.3 Lactobacillaceae 2.3.1.128 ko:K03789 ko00000,ko01000,ko03009 Bacteria 1VEW7@1239,3F5HK@33958,4HPE4@91061,COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase GHBLAFEN_01940 525365.HMPREF0548_0583 3.3e-144 517.7 Lactobacillaceae ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1UMKU@1239,3FBHN@33958,4HCQB@91061,COG3716@1,COG3716@2 NA|NA|NA G PTS system mannose/fructose/sorbose family IID component GHBLAFEN_01941 525365.HMPREF0548_0584 3.4e-41 174.1 Lactobacillaceae ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1UYP8@1239,3FC9E@33958,4HFQS@91061,COG3715@1,COG3715@2 NA|NA|NA G PTS system sorbose-specific iic component GHBLAFEN_01942 1423767.BALU01000015_gene1894 4e-73 280.8 Lactobacillaceae ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1UYP8@1239,3FC9E@33958,4HFQS@91061,COG3715@1,COG3715@2 NA|NA|NA G PTS system sorbose-specific iic component GHBLAFEN_01943 97137.C821_00363 1.8e-76 292.4 Lactobacillaceae 2.7.1.191 ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1TQJ4@1239,3FBI1@33958,4HIM5@91061,COG2893@1,COG2893@2,COG3444@1,COG3444@2 NA|NA|NA G PTS system sorbose subfamily IIB component GHBLAFEN_01944 1423767.BALU01000015_gene1892 1.7e-29 134.8 Bacteria 2.7.1.191 ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria COG2893@1,COG2893@2 NA|NA|NA G phosphoenolpyruvate-dependent sugar phosphotransferase system GHBLAFEN_01945 525365.HMPREF0548_0585 7.3e-155 553.1 Lactobacillaceae Bacteria 1TPM1@1239,3FB4Q@33958,4H9XJ@91061,COG0656@1,COG0656@2 NA|NA|NA S reductase GHBLAFEN_01946 405566.lhv_0581 1.7e-238 831.6 Lactobacillaceae pyrP ko:K02824,ko:K16169 ko00000,ko02000 2.A.40.1.1,2.A.40.1.2,2.A.40.3.1 iLJ478.TM0819 Bacteria 1TQKX@1239,3F3UJ@33958,4HAEU@91061,COG2233@1,COG2233@2 NA|NA|NA F Permease GHBLAFEN_01947 405566.lhv_0582 7.5e-89 333.2 Lactobacillaceae pyrR 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000,ko03000 Bacteria 1V3GV@1239,3F4MT@33958,4HGYE@91061,COG2065@1,COG2065@2 NA|NA|NA F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant GHBLAFEN_01948 405566.lhv_0583 2.1e-258 897.9 Lactobacillaceae emrY Bacteria 1VSW8@1239,3F4AW@33958,4HUQC@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GHBLAFEN_01949 405566.lhv_0584 2.3e-168 598.2 Lactobacillaceae mdtG GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085 ko:K08161 ko00000,ko02000 2.A.1.2.20 Bacteria 1TRDJ@1239,3FCA7@33958,4H9UE@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GHBLAFEN_01950 326425.lhe_0620 5.7e-33 146.4 Lactobacillaceae mdtG GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085 ko:K08161 ko00000,ko02000 2.A.1.2.20 Bacteria 1TRDJ@1239,3FCA7@33958,4H9UE@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GHBLAFEN_01951 326425.lhe_0619 7.8e-210 736.1 Lactobacillaceae pepA Bacteria 1TNZT@1239,3F55I@33958,4H9SM@91061,COG1363@1,COG1363@2 NA|NA|NA E M42 glutamyl aminopeptidase GHBLAFEN_01952 405566.lhv_0586 5.8e-310 1069.3 Lactobacillaceae ybiT GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896 ko:K06158 ko00000,ko03012 Bacteria 1TPW0@1239,3F3ZJ@33958,4HATH@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein GHBLAFEN_01953 405566.lhv_0587 9.9e-146 522.7 Lactobacillaceae Bacteria 1U538@1239,29NJ9@1,309H6@2,3F4AG@33958,4IEUK@91061 NA|NA|NA GHBLAFEN_01954 405566.lhv_0588 4.9e-130 470.3 Lactobacillaceae yfeJ 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1UAH0@1239,3F4AV@33958,4HHTX@91061,COG0518@1,COG0518@2 NA|NA|NA F glutamine amidotransferase GHBLAFEN_01955 326425.lhe_0615 5.5e-147 526.9 Lactobacillaceae glnH ko:K10039 ko02010,map02010 M00228 ko00000,ko00001,ko00002,ko02000 3.A.1.3 Bacteria 1TT11@1239,3FC55@33958,4HBM1@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter GHBLAFEN_01956 326425.lhe_0614 2.2e-79 301.6 Lactobacillaceae Bacteria 1VF1A@1239,3F705@33958,4HH6N@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator, MarR family GHBLAFEN_01957 326425.lhe_0613 5e-291 1006.5 Lactobacillaceae XK27_09600 ko:K06147,ko:K18891 ko02010,map02010 M00708 ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 Bacteria 1TP0B@1239,3F3SP@33958,4H9SC@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter, ATP-binding protein GHBLAFEN_01958 405566.lhv_0592 0.0 1114.4 Lactobacillaceae ko:K06147,ko:K18892 ko02010,map02010 M00708 ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 Bacteria 1UNRI@1239,3FC4R@33958,4HFD4@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region GHBLAFEN_01959 326425.lhe_0611 2.4e-101 374.8 Lactobacillaceae ko:K16925 M00582 ko00000,ko00002,ko02000 3.A.1.30 Bacteria 1V39N@1239,3F4QM@33958,4HF32@91061,COG4721@1,COG4721@2 NA|NA|NA S ABC-type cobalt transport system, permease component GHBLAFEN_01960 525365.HMPREF0548_0604 4.9e-94 350.9 Lactobacillaceae Bacteria 1TS1D@1239,3F4DJ@33958,4HCUB@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator superfamily GHBLAFEN_01961 405566.lhv_0595 4.2e-63 247.3 Lactobacillaceae Bacteria 1TS1D@1239,3F4DJ@33958,4HCUB@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator superfamily GHBLAFEN_01962 405566.lhv_0596 1.3e-81 308.9 Lactobacillaceae udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 iSBO_1134.SBO_0893 Bacteria 1TQ4V@1239,3FCEB@33958,4IQTA@91061,COG0572@1,COG0572@2 NA|NA|NA F Zeta toxin GHBLAFEN_01963 405566.lhv_0596 1.9e-18 97.4 Lactobacillaceae udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 iSBO_1134.SBO_0893 Bacteria 1TQ4V@1239,3FCEB@33958,4IQTA@91061,COG0572@1,COG0572@2 NA|NA|NA F Zeta toxin GHBLAFEN_01964 1117379.BABA_24851 4.1e-78 298.1 Bacillus Bacteria 1UZVA@1239,1ZN8I@1386,4HHAJ@91061,COG3039@1,COG3039@2 NA|NA|NA L Transposase DDE domain GHBLAFEN_01965 1423743.JCM14108_3042 9.1e-40 170.6 Lactobacillaceae 3.6.4.12 ko:K02314,ko:K02316,ko:K17680 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03029,ko03032 Bacteria 1V1I5@1239,3F7KN@33958,4IG43@91061,COG0305@1,COG0305@2,COG0358@1,COG0358@2 NA|NA|NA L DnaB-like helicase C terminal domain GHBLAFEN_01966 326425.lhe_1057 0.0 2878.2 Lactobacillaceae Bacteria 1TPH1@1239,3F3M5@33958,4HBQH@91061,COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family GHBLAFEN_01967 1423767.BALU01000008_gene608 4.4e-84 317.8 Lactobacillaceae Bacteria 1VDYG@1239,2C6BP@1,32SQP@2,3F5TH@33958,4HS7C@91061 NA|NA|NA GHBLAFEN_01968 891391.LAC30SC_05335 1.2e-26 125.9 Lactobacillaceae Bacteria 1U5RF@1239,2A1GN@1,30PQ9@2,3F6DA@33958,4IFFK@91061 NA|NA|NA GHBLAFEN_01969 326425.lhe_0388 1.1e-81 309.3 Lactobacillaceae Bacteria 1V6P0@1239,3F63I@33958,4HJ1Y@91061,COG3610@1,COG3610@2 NA|NA|NA S Threonine/Serine exporter, ThrE GHBLAFEN_01970 405566.lhv_1828 4.4e-138 497.3 Lactobacillaceae thrE Bacteria 1TSE8@1239,3F4XE@33958,4HBW1@91061,COG2966@1,COG2966@2 NA|NA|NA S Putative threonine/serine exporter GHBLAFEN_01971 405566.lhv_1829 4.6e-288 996.5 Lactobacillaceae ko:K06158 ko00000,ko03012 Bacteria 1TPAX@1239,3FC7X@33958,4HC58@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter GHBLAFEN_01972 891391.LAC30SC_09505 1e-55 222.6 Lactobacillaceae Bacteria 1U5V0@1239,29NYN@1,309WR@2,3F6IV@33958,4IFIN@91061 NA|NA|NA GHBLAFEN_01973 326425.lhe_0384 7.6e-100 369.8 Lactobacillaceae rimL ko:K03817 ko00000,ko01000,ko03009 Bacteria 1V3NE@1239,3F6YW@33958,4HG1N@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain GHBLAFEN_01974 1423748.BALB01000012_gene1196 1.2e-86 325.9 Lactobacillaceae ko:K07150 ko00000 Bacteria 1U5PM@1239,3F56J@33958,4HEHT@91061,COG1811@1,COG1811@2 NA|NA|NA S Protein of unknown function (DUF554) GHBLAFEN_01975 1423748.BALB01000012_gene1196 1.3e-10 71.6 Lactobacillaceae ko:K07150 ko00000 Bacteria 1U5PM@1239,3F56J@33958,4HEHT@91061,COG1811@1,COG1811@2 NA|NA|NA S Protein of unknown function (DUF554) GHBLAFEN_01976 405566.lhv_1834 1.1e-212 745.7 Lactobacillaceae brpA Bacteria 1TR1B@1239,3F3MQ@33958,4HA09@91061,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-like function transcriptional attenuator common domain protein GHBLAFEN_01977 326425.lhe_0381 0.0 1191.0 Lactobacillaceae pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 ko:K08602 ko00000,ko01000,ko01002 Bacteria 1TP4P@1239,3F4E5@33958,4HA7X@91061,COG1164@1,COG1164@2 NA|NA|NA E oligoendopeptidase F GHBLAFEN_01978 525365.HMPREF0548_1576 1.1e-22 112.5 Bacilli Z012_06740 Bacteria 1TZWX@1239,4HGN9@91061,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family GHBLAFEN_01979 573061.Clocel_2651 2.2e-309 1068.1 Clostridiaceae 3.1.21.5 ko:K01156 ko00000,ko01000,ko02048 Bacteria 1UQNX@1239,24AW2@186801,36HIF@31979,COG1061@1,COG1061@2 NA|NA|NA L Type III restriction enzyme, res subunit GHBLAFEN_01980 397288.C806_00539 8.1e-187 660.6 unclassified Lachnospiraceae 2.1.1.72 ko:K07316 ko00000,ko01000,ko02048 Bacteria 1TR8A@1239,25MPY@186801,27PEU@186928,COG2189@1,COG2189@2 NA|NA|NA L DNA methylAse GHBLAFEN_01982 326425.lhe_0028 8.3e-120 436.4 Lactobacillaceae yhiD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07507 ko00000,ko02000 9.B.20 Bacteria 1V409@1239,3F3QE@33958,4HK8H@91061,COG1285@1,COG1285@2 NA|NA|NA S MgtC family GHBLAFEN_01983 326425.lhe_0027 7.5e-241 839.3 Lactobacillaceae Bacteria 1UHVZ@1239,3F3SU@33958,4ISGG@91061,COG2267@1,COG2267@2 NA|NA|NA I Protein of unknown function (DUF2974) GHBLAFEN_01984 405566.lhv_0024 4.7e-36 156.8 Lactobacillaceae Bacteria 1U7X6@1239,2BNBG@1,32GZ3@2,3FAA7@33958,4IHUJ@91061 NA|NA|NA GHBLAFEN_01986 1033837.WANG_1563 4.8e-62 243.8 Lactobacillaceae hsdS 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1TT1D@1239,3F6TD@33958,4HTQA@91061,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain GHBLAFEN_01987 405566.lhv_1480 1.1e-275 955.3 Lactobacillaceae hsdM GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1TPGZ@1239,3F4HM@33958,4HA1J@91061,COG0286@1,COG0286@2 NA|NA|NA V type I restriction-modification system GHBLAFEN_01988 405566.lhv_1481 0.0 2093.5 Lactobacillaceae hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 1UI7V@1239,3F4JF@33958,4HA94@91061,COG4096@1,COG4096@2 NA|NA|NA L DEAD/DEAH box helicase GHBLAFEN_01989 1033837.WANG_1559 8e-226 789.6 Lactobacillaceae Bacteria 1UYJN@1239,3FBEE@33958,4HF8I@91061,COG4640@1,COG4640@2 NA|NA|NA S response to antibiotic GHBLAFEN_01990 405566.lhv_0091 2.1e-51 208.0 Lactobacillaceae ko:K07493 ko00000 Bacteria 1TP4C@1239,3F4RA@33958,4HAXJ@91061,COG3328@1,COG3328@2 NA|NA|NA L Transposase GHBLAFEN_01991 326425.lhe_1891 0.0 1139.8 Lactobacillaceae cadA Bacteria 1TQ07@1239,3F4JI@33958,4H9SP@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase GHBLAFEN_01992 405566.lhv_2065 1.2e-203 715.7 Lactobacillaceae napA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 Bacteria 1TS32@1239,3FCEG@33958,4HP0X@91061,COG0475@1,COG0475@2 NA|NA|NA P Sodium/hydrogen exchanger family GHBLAFEN_01993 1423748.BALB01000014_gene1354 5.8e-49 199.9 Lactobacillaceae yefM 2.3.1.15 ko:K08591,ko:K19158,ko:K19159 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004,ko02048 Bacteria 1U6UC@1239,3F8I1@33958,4IGN6@91061,COG2161@1,COG2161@2 NA|NA|NA D Antitoxin component of a toxin-antitoxin (TA) module GHBLAFEN_01994 405566.lhv_2907 3.6e-47 193.7 Lactobacillaceae ko:K19158 ko00000,ko01000,ko02048 Bacteria 1VEN0@1239,3F80N@33958,4HRVW@91061,COG4115@1,COG4115@2 NA|NA|NA S YoeB-like toxin of bacterial type II toxin-antitoxin system GHBLAFEN_01995 405566.lhv_2067 4.4e-262 910.2 Lactobacillaceae ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TSRV@1239,3F3JJ@33958,4HIAU@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region GHBLAFEN_01996 405566.lhv_2068 1.9e-75 288.9 Lactobacillaceae Bacteria 1VKFR@1239,3F701@33958,4HKWD@91061,COG3595@1,COG3595@2 NA|NA|NA S Putative adhesin GHBLAFEN_01997 326425.lhe_1896 1.5e-155 555.4 Lactobacillaceae mutR ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria 1U54X@1239,3F4P7@33958,4IEW2@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins GHBLAFEN_01998 326425.lhe_1897 1.6e-45 188.3 Lactobacillaceae Bacteria 1U6UW@1239,2BRU7@1,32KUC@2,3F8IR@33958,4IGNS@91061 NA|NA|NA GHBLAFEN_01999 405566.lhv_1689 6.6e-290 1002.7 Lactobacillaceae Bacteria 1TSRV@1239,3F46B@33958,4HCIZ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC-type multidrug transport system, ATPase and permease components GHBLAFEN_02000 405566.lhv_1688 3.7e-285 986.9 Lactobacillaceae Bacteria 1TSRV@1239,3F46B@33958,4HCIZ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC-type multidrug transport system, ATPase and permease components GHBLAFEN_02002 525365.HMPREF0548_1616 4.4e-16 90.1 Lactobacillaceae ko:K07484 ko00000 Bacteria 1VAJD@1239,3F7E1@33958,4HKCG@91061,COG3436@1,COG3436@2 NA|NA|NA L PFAM IS66 Orf2 family protein GHBLAFEN_02003 1423748.BALB01000013_gene1259 3.3e-09 67.0 Lactobacillaceae Bacteria 1U6J6@1239,29PG8@1,30AED@2,3F80S@33958,4IGBQ@91061 NA|NA|NA GHBLAFEN_02004 748671.LCRIS_00811 9.6e-14 82.4 Lactobacillaceae Bacteria 1VHME@1239,3F7IG@33958,4IRT3@91061,COG4679@1,COG4679@2 NA|NA|NA S Phage derived protein Gp49-like (DUF891) GHBLAFEN_02005 326425.lhe_1553 1.5e-40 171.8 Lactobacillaceae Bacteria 1VMY1@1239,3F814@33958,4HRA4@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins GHBLAFEN_02006 405566.lhv_1685 5.3e-43 179.9 Lactobacillaceae Bacteria 1U6BA@1239,2DKPI@1,30A82@2,3F7I5@33958,4IG2X@91061 NA|NA|NA GHBLAFEN_02007 525365.HMPREF0548_0588 2.8e-21 107.1 Lactobacillaceae ko:K07171 ko00000,ko01000,ko02048 Bacteria 1U642@1239,3F6ZN@33958,4IFTM@91061,COG2337@1,COG2337@2 NA|NA|NA T PemK-like, MazF-like toxin of type II toxin-antitoxin system GHBLAFEN_02008 525365.HMPREF0548_0311 6.8e-66 256.5 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TQAH@1239,3FBNH@33958,4IRBD@91061,COG0675@1,COG0675@2 NA|NA|NA L Probable transposase GHBLAFEN_02009 525365.HMPREF0548_0311 1e-162 579.3 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TQAH@1239,3FBNH@33958,4IRBD@91061,COG0675@1,COG0675@2 NA|NA|NA L Probable transposase GHBLAFEN_02010 1423754.BALY01000020_gene763 2.5e-14 84.3 Lactobacillaceae Bacteria 1TZWX@1239,3F4I5@33958,4HFD7@91061,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family GHBLAFEN_02011 1291743.LOSG293_220250 2.6e-121 441.4 Lactobacillaceae traI 5.99.1.2 ko:K03169 ko00000,ko01000,ko03032 Bacteria 1TPJD@1239,3F4W6@33958,4HAZV@91061,COG0550@1,COG0550@2 NA|NA|NA L This gene contains a nucleotide ambiguity which may be the result of a sequencing error GHBLAFEN_02012 1423780.LOT_2221 0.0 1251.1 Lactobacillaceae Bacteria 1VQWC@1239,3F4DP@33958,4HD6B@91061,COG0507@1,COG0507@2 NA|NA|NA L MobA MobL family protein GHBLAFEN_02013 908339.HMPREF9265_1193 6.3e-23 112.8 Lactobacillaceae Bacteria 1U69C@1239,29P8B@1,30A6E@2,3F7CM@33958,4IG0H@91061 NA|NA|NA GHBLAFEN_02014 511437.Lbuc_2385 2.6e-40 171.0 Lactobacillaceae Bacteria 1VKZC@1239,2EJES@1,33D5R@2,3F6Y2@33958,4HRGI@91061 NA|NA|NA GHBLAFEN_02015 908339.HMPREF9265_1393 4.1e-125 454.1 Lactobacillaceae Bacteria 1V3AX@1239,3F4YX@33958,4HVK3@91061,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family GHBLAFEN_02016 272621.LBA0072 1.4e-128 465.7 Lactobacillaceae arbV 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1V9P5@1239,3F4RC@33958,4IPQB@91061,COG0204@1,COG0204@2 NA|NA|NA I Acyl-transferase GHBLAFEN_02017 326425.lhe_0094 1.7e-143 515.4 Lactobacillaceae arbx Bacteria 1UY4M@1239,3F4YZ@33958,4IEY6@91061,COG1442@1,COG1442@2 NA|NA|NA M Glycosyl transferase family 8 GHBLAFEN_02018 405566.lhv_0076 1.7e-184 651.7 Lactobacillaceae arbY GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0016740,GO:0016757,GO:0043170,GO:0044238,GO:0071704,GO:1901576 Bacteria 1VGDI@1239,3FCDT@33958,4I0ZW@91061,COG1442@1,COG1442@2 NA|NA|NA M Glycosyl transferase family 8 GHBLAFEN_02019 525365.HMPREF0548_1834 5.3e-162 577.0 Lactobacillaceae arbY GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0016740,GO:0016757,GO:0043170,GO:0044238,GO:0071704,GO:1901576 Bacteria 1VGDI@1239,3FBE4@33958,4IPQC@91061,COG1442@1,COG1442@2 NA|NA|NA M Glycosyl transferase family 8 GHBLAFEN_02020 405566.lhv_0074 7.3e-166 589.7 Lactobacillaceae arbZ Bacteria 1V2F4@1239,3F5FU@33958,4IF2T@91061,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases GHBLAFEN_02021 405566.lhv_2203 1.3e-34 151.8 Firmicutes Bacteria 1V64Y@1239,COG4892@1,COG4892@2 NA|NA|NA S Cytochrome b5 GHBLAFEN_02022 405566.lhv_0073 3.8e-108 397.5 Lactobacillaceae Bacteria 1TRVX@1239,3F48I@33958,4HFSV@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator, LysR family GHBLAFEN_02023 1423748.BALB01000037_gene1992 3.7e-98 364.4 Lactobacillaceae Bacteria 1V3HS@1239,3F4HP@33958,4IQPW@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain GHBLAFEN_02024 1423748.BALB01000037_gene1992 2e-41 174.9 Lactobacillaceae Bacteria 1V3HS@1239,3F4HP@33958,4IQPW@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain GHBLAFEN_02025 326425.lhe_0379 2.1e-42 177.9 Lactobacillaceae Bacteria 1U6IT@1239,29PFZ@1,30AE4@2,3F800@33958,4IGB6@91061 NA|NA|NA S Enterocin A Immunity GHBLAFEN_02026 1423748.BALB01000012_gene1200 3.6e-52 210.7 Lactobacillaceae lctP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03303 ko00000,ko02000 2.A.14 Bacteria 1TQNM@1239,3F4EG@33958,4HAF3@91061,COG1620@1,COG1620@2 NA|NA|NA C L-lactate permease GHBLAFEN_02027 1423748.BALB01000012_gene1200 1.4e-89 335.9 Lactobacillaceae lctP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03303 ko00000,ko02000 2.A.14 Bacteria 1TQNM@1239,3F4EG@33958,4HAF3@91061,COG1620@1,COG1620@2 NA|NA|NA C L-lactate permease GHBLAFEN_02028 1423748.BALB01000012_gene1200 4.1e-35 153.7 Lactobacillaceae lctP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03303 ko00000,ko02000 2.A.14 Bacteria 1TQNM@1239,3F4EG@33958,4HAF3@91061,COG1620@1,COG1620@2 NA|NA|NA C L-lactate permease GHBLAFEN_02029 326425.lhe_0377 9.9e-234 815.8 Lactobacillaceae ydjN GO:0000099,GO:0000101,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006791,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015184,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015811,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:0098656,GO:1901682,GO:1902475,GO:1903825,GO:1905039 ko:K06956 ko00000 Bacteria 1UPUK@1239,3FB7M@33958,4HAJY@91061,COG1823@1,COG1823@2 NA|NA|NA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family GHBLAFEN_02030 326425.lhe_0376 2.6e-130 471.5 Lactobacillaceae znuB ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 1V0SX@1239,3F4BC@33958,4HE09@91061,COG1108@1,COG1108@2 NA|NA|NA U ABC 3 transport family GHBLAFEN_02031 326425.lhe_0375 1.6e-117 428.7 Lactobacillaceae fhuC ko:K02074,ko:K09817 ko02010,map02010 M00242,M00244 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 1TQ68@1239,3F49M@33958,4HAZI@91061,COG1121@1,COG1121@2 NA|NA|NA P ABC transporter GHBLAFEN_02032 405566.lhv_1842 4.4e-158 563.9 Lactobacillaceae psaA ko:K02077 M00244 ko00000,ko00002,ko02000 3.A.1.15 Bacteria 1TRKU@1239,3F4B9@33958,4HAKT@91061,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family GHBLAFEN_02033 1423748.BALB01000012_gene1204 5.1e-41 173.3 Lactobacillaceae Bacteria 1VA6G@1239,3F72A@33958,4HKYT@91061,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor GHBLAFEN_02034 326425.lhe_0390 1.6e-67 262.3 Lactobacillaceae Bacteria 1UFZH@1239,29V33@1,30GGE@2,3F5BQ@33958,4IF1H@91061 NA|NA|NA GHBLAFEN_02035 1423748.BALB01000044_gene2046 4e-11 72.8 Lactobacillaceae nrdF 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1TQTH@1239,3F3P1@33958,4H9WX@91061,COG0208@1,COG0208@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides GHBLAFEN_02036 1423748.BALB01000044_gene2047 1.2e-74 285.8 Lactobacillaceae nrdI ko:K03647 ko00000 Bacteria 1V71V@1239,3F6JF@33958,4HIW7@91061,COG1780@1,COG1780@2 NA|NA|NA F Belongs to the NrdI family GHBLAFEN_02037 326425.lhe_0393 2.8e-95 354.8 Lactobacillaceae Bacteria 1U55V@1239,29DQI@1,300NC@2,3F4UQ@33958,4IEX6@91061 NA|NA|NA GHBLAFEN_02038 326425.lhe_0394 4.2e-278 963.4 Lactobacillaceae Bacteria 1V7RP@1239,2EZVI@1,33T01@2,3F4QD@33958,4IEWB@91061 NA|NA|NA S O-antigen ligase like membrane protein GHBLAFEN_02039 326425.lhe_0395 4.3e-25 120.6 Lactobacillaceae Bacteria 1U6CF@1239,2DKPT@1,30A91@2,3F7KP@33958,4IG44@91061 NA|NA|NA GHBLAFEN_02040 326425.lhe_0396 5e-96 357.1 Lactobacillaceae gmk2 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1VGNR@1239,3FBPU@33958,4IRT6@91061,COG0194@1,COG0194@2 NA|NA|NA F Guanylate kinase homologues. GHBLAFEN_02041 326425.lhe_0397 6.2e-94 350.1 Lactobacillaceae ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1V5H7@1239,3F4VI@33958,4IEXC@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family GHBLAFEN_02042 525365.HMPREF0548_1594 6.3e-31 139.8 Lactobacillaceae ko:K06921 ko00000 Bacteria 1TR21@1239,3F57U@33958,4HF7F@91061,COG1672@1,COG1672@2 NA|NA|NA S Archaea bacterial proteins of unknown function GHBLAFEN_02043 525365.HMPREF0548_1594 8.8e-58 229.6 Lactobacillaceae ko:K06921 ko00000 Bacteria 1TR21@1239,3F57U@33958,4HF7F@91061,COG1672@1,COG1672@2 NA|NA|NA S Archaea bacterial proteins of unknown function GHBLAFEN_02044 405566.lhv_0937 7.2e-135 486.5 Lactobacillaceae gmuR ko:K03492,ko:K03710 ko00000,ko03000 Bacteria 1V0UW@1239,3FC8M@33958,4HD10@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA GHBLAFEN_02045 1423767.BALU01000002_gene1646 9.7e-63 246.1 Lactobacillaceae pts23C ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 Bacteria 1VTVX@1239,3FC6X@33958,4HFKM@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane GHBLAFEN_02046 1423790.BN53_01845 2.5e-135 488.4 Lactobacillaceae pts23C ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 Bacteria 1VTVX@1239,3FC6X@33958,4HFKM@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane GHBLAFEN_02047 326425.lhe_0892 3.2e-277 960.3 Lactobacillaceae pbg6 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3FC7C@33958,4HDER@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family GHBLAFEN_02048 1423748.BALB01000019_gene1559 2e-80 305.1 Lactobacillaceae ypbG 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1UZ80@1239,3FBD4@33958,4HD5J@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family GHBLAFEN_02049 1423748.BALB01000019_gene1559 7.7e-11 72.0 Lactobacillaceae ypbG 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1UZ80@1239,3FBD4@33958,4HD5J@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family GHBLAFEN_02050 405566.lhv_0943 1.6e-85 322.0 Lactobacillaceae Bacteria 1UYXM@1239,3F667@33958,4HD96@91061,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase GHBLAFEN_02051 326425.lhe_0895 1.7e-65 255.8 Lactobacillaceae Bacteria 1VZSI@1239,29W71@1,30HS8@2,3F6RP@33958,4IFNQ@91061 NA|NA|NA S Domain of unknown function (DUF4767) GHBLAFEN_02052 326425.lhe_0896 1.2e-244 852.0 Lactobacillaceae eno GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0043236,GO:0050840 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 1V12I@1239,3FCCA@33958,4HTD2@91061,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis GHBLAFEN_02053 748671.LCRIS_00904 6.6e-132 476.9 Lactobacillaceae yitS Bacteria 1V0RC@1239,3F4PM@33958,4HBSA@91061,COG1307@1,COG1307@2 NA|NA|NA S Uncharacterised protein, DegV family COG1307 GHBLAFEN_02054 405566.lhv_0949 2.3e-99 368.2 Lactobacillaceae 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1U506@1239,3F3M2@33958,4IES2@91061,COG0671@1,COG0671@2 NA|NA|NA I Acid phosphatase homologues GHBLAFEN_02055 748671.LCRIS_00906 2.5e-31 141.0 Lactobacillaceae cbh 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 1TPZS@1239,3F4NH@33958,4HC4Y@91061,COG3049@1,COG3049@2 NA|NA|NA M Linear amide C-N hydrolase, choloylglycine hydrolase family protein GHBLAFEN_02056 891391.LAC30SC_04505 3e-123 448.0 Lactobacillaceae cbh 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 1TPZS@1239,3F4NH@33958,4HC4Y@91061,COG3049@1,COG3049@2 NA|NA|NA M Linear amide C-N hydrolase, choloylglycine hydrolase family protein GHBLAFEN_02058 405566.lhv_0953 5e-57 227.3 Lactobacillaceae Bacteria 1TUVJ@1239,3F8JH@33958,4IE4X@91061,COG1598@1,COG1598@2 NA|NA|NA S PFAM Uncharacterised protein family UPF0150 GHBLAFEN_02059 405566.lhv_0954 7.9e-247 859.4 Lactobacillaceae yifK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03293 ko00000 2.A.3.1 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease GHBLAFEN_02060 326425.lhe_0901 2.8e-187 661.0 Lactobacillaceae thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSIR@1239,3F3SB@33958,4H9QS@91061,COG0207@1,COG0207@2 NA|NA|NA F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis GHBLAFEN_02061 326425.lhe_0902 2.4e-95 354.8 Lactobacillaceae folA 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 Bacteria 1VB80@1239,3F6Y4@33958,4HIGJ@91061,COG0262@1,COG0262@2 NA|NA|NA H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis GHBLAFEN_02062 1423748.BALB01000023_gene1731 1.1e-14 85.5 Bacteria ps301 Bacteria COG2944@1,COG2944@2 NA|NA|NA K sequence-specific DNA binding GHBLAFEN_02063 1423748.BALB01000023_gene1731 3.8e-16 90.1 Bacteria ps301 Bacteria COG2944@1,COG2944@2 NA|NA|NA K sequence-specific DNA binding GHBLAFEN_02064 405566.lhv_0959 0.0 1389.4 Lactobacillaceae aha1 ko:K12952 ko00000,ko01000 3.A.3.23 Bacteria 1TPF5@1239,3F4Y1@33958,4H9ZI@91061,COG0474@1,COG0474@2 NA|NA|NA P E1-E2 ATPase GHBLAFEN_02065 405566.lhv_0960 4.8e-162 577.0 Lactobacillaceae metQ1 ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TQAS@1239,3F3WP@33958,4HCTA@91061,COG1464@1,COG1464@2 NA|NA|NA P Belongs to the nlpA lipoprotein family GHBLAFEN_02066 405566.lhv_0961 2.3e-190 671.4 Lactobacillaceae metN ko:K02071 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TPPN@1239,3F3U5@33958,4H9VX@91061,COG1135@1,COG1135@2 NA|NA|NA P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system GHBLAFEN_02067 326425.lhe_0907 6.4e-88 330.5 Lactobacillaceae metI ko:K02072 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TRSY@1239,3F48A@33958,4HBEV@91061,COG2011@1,COG2011@2 NA|NA|NA P ABC transporter permease GHBLAFEN_02068 1423767.BALU01000004_gene1377 1.9e-188 665.2 Lactobacillaceae ko:K07133 ko00000 Bacteria 1TP7X@1239,3F51K@33958,4HCSJ@91061,COG1373@1,COG1373@2 NA|NA|NA S cog cog1373 GHBLAFEN_02069 326425.lhe_0909 1.7e-34 151.4 Lactobacillaceae Bacteria 1U797@1239,29PZQ@1,30AY5@2,3F957@33958,4IH43@91061 NA|NA|NA GHBLAFEN_02070 405566.lhv_0968 4.5e-266 923.3 Lactobacillaceae fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHPH@1239,3F3K0@33958,4HA6P@91061,COG0114@1,COG0114@2 NA|NA|NA C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate GHBLAFEN_02071 326425.lhe_0911 1.6e-263 914.8 Lactobacillaceae frdC 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAR@1239,3F3KJ@33958,4HAXN@91061,COG1053@1,COG1053@2 NA|NA|NA C FAD binding domain GHBLAFEN_02072 1033837.WANG_0179 2.8e-19 102.1 Lactobacillaceae ko:K02487 ko02020,map02020 M00507 ko00000,ko00001,ko00002,ko02022,ko02035 Bacteria 1VSP5@1239,3F4FY@33958,4HUK1@91061,COG3266@1,COG3266@2 NA|NA|NA UW LPXTG-motif cell wall anchor domain protein GHBLAFEN_02073 97137.C821_01757 2.1e-16 93.2 Lactobacillaceae 3.5.1.28 ko:K01448,ko:K13733,ko:K20276 ko01503,ko02024,ko05100,map01503,map02024,map05100 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria 1VSP5@1239,3F4FY@33958,4HUK1@91061,COG3266@1,COG3266@2,COG4932@1,COG4932@2 NA|NA|NA UW LPXTG-motif cell wall anchor domain protein GHBLAFEN_02075 326425.lhe_0913 2.2e-168 598.2 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPSY@1239,3F3RM@33958,4HB0Z@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily. LDH family GHBLAFEN_02076 272621.LBA1634 1.9e-73 283.9 Lactobacillaceae fhaB GO:0005575,GO:0005623,GO:0009986,GO:0044464 ko:K15125,ko:K18491 ko04550,ko05133,map04550,map05133 ko00000,ko00001,ko00536,ko03000 Bacteria 1UHXY@1239,3F52E@33958,4ISAC@91061,COG2373@1,COG2373@2,COG3064@1,COG3064@2 NA|NA|NA M Rib/alpha-like repeat GHBLAFEN_02077 1033837.WANG_0753 2.1e-43 182.2 Lactobacillaceae Bacteria 1UJGB@1239,29X4C@1,30IT6@2,3F6JZ@33958,4IT92@91061 NA|NA|NA GHBLAFEN_02078 405566.lhv_0980 2.5e-44 184.5 Lactobacillaceae Bacteria 1UJGB@1239,29X4C@1,30IT6@2,3F6JZ@33958,4IT92@91061 NA|NA|NA GHBLAFEN_02079 326425.lhe_0914 1.9e-258 897.9 Lactobacillaceae pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 1TRJN@1239,3F5DQ@33958,4HBZ9@91061,COG3579@1,COG3579@2 NA|NA|NA E Peptidase C1-like family GHBLAFEN_02080 326425.lhe_0915 4.4e-272 943.3 Lactobacillaceae ko:K03319 ko00000 2.A.47 Bacteria 1TSGE@1239,3F4RH@33958,4HDE4@91061,COG0471@1,COG0471@2 NA|NA|NA P Sodium:sulfate symporter transmembrane region GHBLAFEN_02081 326425.lhe_0916 1.1e-152 545.8 Lactobacillaceae ydjP Bacteria 1TR25@1239,3F4FI@33958,4HMJ7@91061,COG2267@1,COG2267@2 NA|NA|NA I Alpha/beta hydrolase family GHBLAFEN_02082 405566.lhv_0987 2.1e-196 691.4 Lactobacillaceae citC 6.2.1.22 ko:K01910 ko02020,map02020 R04449 RC00012,RC00039 ko00000,ko00001,ko01000 Bacteria 1TSGQ@1239,3F4H7@33958,4HC6Q@91061,COG3053@1,COG3053@2 NA|NA|NA H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase GHBLAFEN_02083 326425.lhe_0918 9.1e-44 182.6 Lactobacillaceae citD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008815,GO:0009346,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016833,GO:0032991,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 ko:K01646 ko02020,map02020 R00362 RC00067,RC01118 ko00000,ko00001 Bacteria 1VEZZ@1239,3F7FR@33958,4HNXD@91061,COG3052@1,COG3052@2 NA|NA|NA C Covalent carrier of the coenzyme of citrate lyase GHBLAFEN_02084 1423748.BALB01000010_gene1076 8.2e-168 596.3 Lactobacillaceae citE 4.1.3.25,4.1.3.34 ko:K01644,ko:K18292 ko00660,ko01100,ko02020,map00660,map01100,map02020 R00237,R00362 RC00067,RC00502,RC01118,RC01205 ko00000,ko00001,ko01000 Bacteria 1TPDY@1239,3F47Q@33958,4HD40@91061,COG2301@1,COG2301@2 NA|NA|NA G Belongs to the HpcH HpaI aldolase family GHBLAFEN_02085 405566.lhv_0990 2.1e-288 997.7 Lactobacillaceae citF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.8.3.10 ko:K01643 ko02020,map02020 R00362 RC00067,RC01118 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_0634 Bacteria 1TPN3@1239,3F4EA@33958,4HAE1@91061,COG3051@1,COG3051@2 NA|NA|NA H Citrate (pro-3S)-lyase alpha chain GHBLAFEN_02086 326425.lhe_0921 2.8e-91 342.4 Lactobacillaceae Bacteria 1VNWP@1239,2DBU6@1,2ZB4C@2,3F51G@33958,4HRN6@91061 NA|NA|NA GHBLAFEN_02087 1158602.I590_03070 1.2e-75 289.3 Enterococcaceae M1-431 Bacteria 1TSF1@1239,4B123@81852,4HHG3@91061,COG4283@1,COG4283@2 NA|NA|NA S Protein of unknown function (DUF1706) GHBLAFEN_02088 1423748.BALB01000010_gene1078 2.1e-71 275.0 Lactobacillaceae yeaL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1V7JN@1239,3F68U@33958,4HINS@91061,COG2707@1,COG2707@2 NA|NA|NA S Protein of unknown function (DUF441) GHBLAFEN_02089 326425.lhe_0923 1e-09 68.6 Lactobacillaceae Bacteria 1U6Q0@1239,29PJU@1,30AHZ@2,3F8A1@33958,4IGGY@91061 NA|NA|NA GHBLAFEN_02090 405566.lhv_0997 8e-146 523.1 Lactobacillaceae cbiQ ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 iSB619.SA_RS14165 Bacteria 1TPMV@1239,3F3Y9@33958,4HBTW@91061,COG0619@1,COG0619@2 NA|NA|NA P cobalt transport GHBLAFEN_02091 405566.lhv_0998 0.0 1120.5 Lactobacillaceae ykoD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 ko:K02006,ko:K16786,ko:K16787 ko02010,map02010 M00245,M00246,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPH8@1239,3F4XP@33958,4HAJM@91061,COG1122@1,COG1122@2 NA|NA|NA P ABC transporter, ATP-binding protein GHBLAFEN_02092 326425.lhe_0926 1.4e-93 349.0 Lactobacillaceae ko:K16924,ko:K16927 M00582 ko00000,ko00002,ko02000 3.A.1.29,3.A.1.32 Bacteria 1V1GT@1239,3F5A7@33958,4HGAE@91061,COG4720@1,COG4720@2 NA|NA|NA S UPF0397 protein GHBLAFEN_02093 405566.lhv_1001 2.2e-66 258.1 Lactobacillaceae Bacteria 1U6UG@1239,29PNX@1,30AM4@2,3F8I6@33958,4IGNA@91061 NA|NA|NA S Domain of unknown function DUF1828 GHBLAFEN_02094 326425.lhe_0928 1.6e-16 90.9 Lactobacillaceae Bacteria 1U734@1239,29PV8@1,30ATG@2,3F8WW@33958,4IGXN@91061 NA|NA|NA GHBLAFEN_02095 405566.lhv_2408 2.7e-51 208.0 Lactobacillaceae Bacteria 1W494@1239,2CHWU@1,34CGV@2,3F71N@33958,4HZJS@91061 NA|NA|NA GHBLAFEN_02096 326425.lhe_0929 4.7e-174 617.1 Lactobacillaceae citR Bacteria 1VSYQ@1239,3FCBZ@33958,4HU6A@91061,COG2390@1,COG2390@2 NA|NA|NA K Putative sugar-binding domain GHBLAFEN_02097 405566.lhv_1004 3.1e-248 864.0 Lactobacillaceae yjjP Bacteria 1TNZH@1239,3F4FR@33958,4HU4D@91061,COG2966@1,COG2966@2,COG3610@1,COG3610@2 NA|NA|NA S Putative threonine/serine exporter GHBLAFEN_02098 326425.lhe_0931 5.5e-97 360.1 Lactobacillaceae yxkA ko:K06910 ko00000 Bacteria 1VJEE@1239,3FBPI@33958,4IRQB@91061,COG1881@1,COG1881@2 NA|NA|NA S Phosphatidylethanolamine-binding protein GHBLAFEN_02099 326425.lhe_0534 1.8e-55 221.9 Lactobacillaceae tagD 2.7.7.15,2.7.7.39 ko:K00968,ko:K00980 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 M00090 R00856,R01890,R02590 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3KY@1239,3F65R@33958,4HGWZ@91061,COG0615@1,COG0615@2 NA|NA|NA IM Glycerol-3-phosphate cytidylyltransferase GHBLAFEN_02100 326425.lhe_0533 1.4e-122 445.7 Lactobacillaceae gntR1 ko:K03710,ko:K11922 ko00000,ko03000 Bacteria 1UYBW@1239,3FC8N@33958,4IPQD@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA GHBLAFEN_02101 326425.lhe_0532 7.8e-213 746.1 Lactobacillaceae Bacteria 1U569@1239,29NKT@1,309IS@2,3F4WR@33958,4IEXJ@91061 NA|NA|NA GHBLAFEN_02104 405566.lhv_0532 1.5e-92 345.5 Lactobacillaceae Bacteria 1W6IZ@1239,28WK8@1,2ZIK8@2,3F68J@33958,4I01D@91061 NA|NA|NA GHBLAFEN_02105 1033837.WANG_1153 3.8e-258 897.1 Lactobacillaceae slpX Bacteria 1U50G@1239,2DKHC@1,309G6@2,3F3S2@33958,4IESF@91061 NA|NA|NA S SLAP domain GHBLAFEN_02106 891391.LAC30SC_02640 1.3e-114 419.5 Lactobacillaceae pfoS ko:K07035 ko00000 Bacteria 1TS5F@1239,3FCB3@33958,4HC4N@91061,COG3641@1,COG3641@2 NA|NA|NA S Phosphotransferase system, EIIC GHBLAFEN_02107 891391.LAC30SC_02640 1.5e-19 101.7 Lactobacillaceae pfoS ko:K07035 ko00000 Bacteria 1TS5F@1239,3FCB3@33958,4HC4N@91061,COG3641@1,COG3641@2 NA|NA|NA S Phosphotransferase system, EIIC GHBLAFEN_02109 797515.HMPREF9103_02051 3.2e-71 274.2 Lactobacillaceae repA Bacteria 1VHQA@1239,2DP1C@1,3304N@2,3F55E@33958,4HPY6@91061 NA|NA|NA S Replication initiator protein A GHBLAFEN_02110 1423754.BALY01000005_gene1234 3.5e-74 285.4 Lactobacillaceae sdrF ko:K14192,ko:K14194,ko:K14201,ko:K20276 ko02024,ko05150,map02024,map05150 ko00000,ko00001 Bacteria 1VNG5@1239,3F5Y1@33958,4HRQD@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein GHBLAFEN_02111 1423754.BALY01000005_gene1233 8.9e-99 367.1 Lactobacillaceae infB ko:K02519,ko:K03832 ko00000,ko02000,ko03012,ko03029 2.C.1.1 Bacteria 1UP8W@1239,3FBZP@33958,4IV2J@91061,COG0810@1,COG0810@2 NA|NA|NA M YSIRK type signal peptide GHBLAFEN_02112 1033837.WANG_1228 2.8e-18 99.8 Lactobacillaceae sdrF ko:K14192,ko:K14194,ko:K14201,ko:K20276 ko02024,ko05150,map02024,map05150 ko00000,ko00001 Bacteria 1VNG5@1239,3F5Y1@33958,4HRQD@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein GHBLAFEN_02113 326425.lhe_0463 8.4e-139 499.6 Lactobacillaceae pnuC ko:K03811 ko00000,ko02000 4.B.1.1 Bacteria 1VE5T@1239,3F3MB@33958,4HMNW@91061,COG3201@1,COG3201@2 NA|NA|NA H nicotinamide mononucleotide transporter GHBLAFEN_02114 1423748.BALB01000051_gene2072 4.1e-11 73.2 Lactobacillaceae Bacteria 1VNWP@1239,2DBU6@1,2ZB4C@2,3F51G@33958,4HRN6@91061 NA|NA|NA GHBLAFEN_02115 326425.lhe_1243 1.4e-161 575.5 Lactobacillaceae yitT Bacteria 1TRBT@1239,3F3PH@33958,4HBPR@91061,COG1284@1,COG1284@2 NA|NA|NA S Uncharacterised 5xTM membrane BCR, YitT family COG1284 GHBLAFEN_02116 1423748.BALB01000007_gene841 1.5e-107 395.6 Lactobacillaceae Bacteria 1U551@1239,29TNS@1,30EWM@2,3F4Q6@33958,4IEWA@91061 NA|NA|NA GHBLAFEN_02117 891391.LAC30SC_06770 4.9e-107 394.0 Lactobacillaceae thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545,iSB619.SA_RS06620 Bacteria 1TRWS@1239,3F44T@33958,4HCQN@91061,COG0083@1,COG0083@2 NA|NA|NA F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate GHBLAFEN_02118 1423748.BALB01000007_gene838 1.6e-122 445.7 Lactobacillaceae hom GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1294,iSB619.SA_RS06610 Bacteria 1TQ2H@1239,3F5BM@33958,4HBAP@91061,COG0460@1,COG0460@2 NA|NA|NA E homoserine dehydrogenase GHBLAFEN_02119 891391.LAC30SC_06785 7.1e-246 856.3 Lactobacillaceae thrC 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS16355,iIT341.HP0098 Bacteria 1TPR0@1239,3F3UF@33958,4H9R7@91061,COG0498@1,COG0498@2 NA|NA|NA E Threonine synthase GHBLAFEN_02120 1423748.BALB01000007_gene836 9.8e-186 656.0 Lactobacillaceae lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iYO844.BSU03790 Bacteria 1TPQJ@1239,3F48V@33958,4HAEP@91061,COG0527@1,COG0527@2 NA|NA|NA E Belongs to the aspartokinase family GHBLAFEN_02122 1423748.BALB01000003_gene491 3.2e-30 137.1 Lactobacillaceae Bacteria 1U6RQ@1239,29PKY@1,30AJ4@2,3F8DH@33958,4IGJ5@91061 NA|NA|NA GHBLAFEN_02124 405566.lhv_1473 6.5e-218 763.1 Lactobacillaceae Bacteria 1UG8H@1239,29V6Q@1,30GKE@2,3F5M6@33958,4IF4J@91061 NA|NA|NA S SLAP domain GHBLAFEN_02126 585524.HMPREF0493_1681 1.2e-70 272.7 Lactobacillaceae mrr GO:0001101,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009295,GO:0009415,GO:0009628,GO:0009987,GO:0010035,GO:0015666,GO:0016787,GO:0016788,GO:0032067,GO:0034641,GO:0042221,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051599,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901700 ko:K07448 ko00000,ko02048 Bacteria 1V1TA@1239,3F5UV@33958,4HC3T@91061,COG1715@1,COG1715@2 NA|NA|NA L restriction endonuclease GHBLAFEN_02127 1423758.BN55_03535 1.1e-57 229.6 Lactobacillaceae mrr GO:0001101,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009295,GO:0009415,GO:0009628,GO:0009987,GO:0010035,GO:0015666,GO:0016787,GO:0016788,GO:0032067,GO:0034641,GO:0042221,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051599,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901700 ko:K07448 ko00000,ko02048 Bacteria 1V1TA@1239,3F5UV@33958,4HC3T@91061,COG1715@1,COG1715@2 NA|NA|NA L restriction endonuclease GHBLAFEN_02130 373903.Hore_20210 6.3e-70 271.2 Clostridia 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1TT1D@1239,24A13@186801,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain GHBLAFEN_02131 326425.lhe_0214 1.9e-124 451.8 Lactobacillaceae XK27_06785 ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQC9@1239,3F3YU@33958,4HB8D@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein GHBLAFEN_02132 891391.LAC30SC_10340 2.3e-113 415.2 Lactobacillaceae XK27_06780 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPHU@1239,3F4HF@33958,4HA2C@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease GHBLAFEN_02133 891391.LAC30SC_10340 6.1e-193 680.2 Lactobacillaceae XK27_06780 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPHU@1239,3F4HF@33958,4HA2C@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease GHBLAFEN_02134 326425.lhe_0212 1.2e-35 155.2 Lactobacillaceae Bacteria 1U6A1@1239,2C9N2@1,30A73@2,3F7ES@33958,4IG19@91061 NA|NA|NA GHBLAFEN_02135 405566.lhv_2052 4.5e-286 989.9 Lactobacillaceae ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03328,ko:K06409 ko00000,ko02000 2.A.66.2,2.A.66.2.14 Bacteria 1TNYX@1239,3F404@33958,4H9RY@91061,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein GHBLAFEN_02136 1423748.BALB01000014_gene1337 3.8e-147 527.7 Lactobacillaceae lysA2 ko:K07273 ko00000 Bacteria 1VF8D@1239,3F4U9@33958,4HX0U@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 GHBLAFEN_02137 1423743.JCM14108_3253 8.7e-44 182.6 Lactobacillaceae relB ko:K07473 ko00000,ko02048 Bacteria 1VGJW@1239,3F72D@33958,4HR7A@91061,COG3077@1,COG3077@2 NA|NA|NA L Addiction module antitoxin, RelB DinJ family GHBLAFEN_02138 1033837.WANG_1726 1.7e-124 452.2 Lactobacillaceae Bacteria 1TRSF@1239,3F3UG@33958,4HDM3@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase, catalytic core GHBLAFEN_02139 1291743.LOSG293_520040 1.8e-62 245.0 Lactobacillaceae Bacteria 1V717@1239,2AK1X@1,31ARI@2,3F6WW@33958,4HIQ9@91061 NA|NA|NA S Pyrimidine dimer DNA glycosylase GHBLAFEN_02140 525309.HMPREF0494_0014 6e-17 92.8 Lactobacillaceae setB Bacteria 1UKXI@1239,3FBWB@33958,4ITKV@91061,COG2211@1,COG2211@2 NA|NA|NA G Major facilitator Superfamily GHBLAFEN_02141 525365.HMPREF0548_1861 1.1e-07 62.8 Lactobacillaceae Bacteria 1U580@1239,29NJD@1,309JD@2,3F53B@33958,4IEZA@91061 NA|NA|NA S Bacteriocin helveticin-J GHBLAFEN_02143 1545702.LACWKB8_1841 1.8e-12 79.3 Lactobacillaceae Bacteria 1U77U@1239,29PYK@1,30AX1@2,3F933@33958,4IH2M@91061 NA|NA|NA GHBLAFEN_02145 405566.lhv_1784 5.8e-163 580.1 Lactobacillaceae galU 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ24@1239,3F45A@33958,4HATY@91061,COG1210@1,COG1210@2 NA|NA|NA M UTP-glucose-1-phosphate uridylyltransferase GHBLAFEN_02146 326425.lhe_0437 0.0 1430.2 Lactobacillaceae yaaO 4.1.1.17,4.1.1.19 ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00133,M00134 R00566,R00670 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 1TNZ9@1239,3F3TV@33958,4HBGC@91061,COG1982@1,COG1982@2 NA|NA|NA E Orn/Lys/Arg decarboxylase, C-terminal domain GHBLAFEN_02147 326425.lhe_0436 1.4e-257 895.2 Lactobacillaceae ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1UYSD@1239,3F48U@33958,4IPMN@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease GHBLAFEN_02149 748671.LCRIS_01240 9.9e-36 156.4 Lactobacillaceae Bacteria 1U7Z5@1239,29QEJ@1,30BDX@2,3FACF@33958,4IHWH@91061 NA|NA|NA GHBLAFEN_02150 1033837.WANG_0328 1.8e-287 994.6 Lactobacillaceae Bacteria 1TSRV@1239,3F3JJ@33958,4HIAU@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region GHBLAFEN_02151 1033837.WANG_0327 0.0 1248.4 Bacilli 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07459 RC00043 ko00000,ko00001,ko01000 Bacteria 1V9AZ@1239,4HIYB@91061,COG0476@1,COG0476@2 NA|NA|NA H ThiF family GHBLAFEN_02152 1033837.WANG_0325 1.5e-288 998.0 Lactobacillaceae lsa ko:K06158,ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000,ko03012 3.A.1.121 Bacteria 1TNYS@1239,3F53D@33958,4HBFK@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter GHBLAFEN_02153 1033837.WANG_1753 2.2e-72 278.5 Lactobacillaceae metQ_4 ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1V0Z6@1239,3FC6K@33958,4HBBW@91061,COG1464@1,COG1464@2 NA|NA|NA P Belongs to the nlpA lipoprotein family GHBLAFEN_02154 525318.HMPREF0497_0232 1.4e-84 319.3 Lactobacillaceae Bacteria 1TRQC@1239,3F4FH@33958,4HD7P@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase GHBLAFEN_02155 1033837.WANG_1754 4.7e-193 680.2 Lactobacillaceae nrdF GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0030145,GO:0032991,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 iECNA114_1301.ECNA114_2708,iECSF_1327.ECSF_2473,iSFV_1184.SFV_2827,iSF_1195.SF2704,iSFxv_1172.SFxv_2966,iS_1188.S2890 Bacteria 1TQTH@1239,3F3P1@33958,4H9WX@91061,COG0208@1,COG0208@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides GHBLAFEN_02156 1033837.WANG_1755 1.2e-73 282.3 Bacteria nrdI GO:0000166,GO:0003674,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0019538,GO:0032553,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564 ko:K03647 ko00000 Bacteria COG1780@1,COG1780@2 NA|NA|NA F Probably involved in ribonucleotide reductase function GHBLAFEN_02157 1033837.WANG_1756 0.0 1417.1 Lactobacillaceae nrdE GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005971,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0015949,GO:0016020,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0051063,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 iAPECO1_1312.APECO1_3846,iYO844.BSU17380 Bacteria 1TPFH@1239,3F3XG@33958,4H9X0@91061,COG0209@1,COG0209@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides GHBLAFEN_02158 1033837.WANG_1757 7.3e-40 169.5 Lactobacillaceae Bacteria 1U639@1239,29P3Y@1,30A25@2,3F6XR@33958,4IFSM@91061 NA|NA|NA S Enterocin A Immunity GHBLAFEN_02159 326425.lhe_0340 1.2e-118 432.6 Lactobacillaceae devA 3.6.3.25 ko:K02003,ko:K06020,ko:K09810 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 Bacteria 1TQP5@1239,3F4RP@33958,4HBXK@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein GHBLAFEN_02160 405566.lhv_1879 2.6e-165 588.2 Lactobacillaceae hrtB ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TWFZ@1239,3F3K5@33958,4H9RQ@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease GHBLAFEN_02161 326425.lhe_0338 4.5e-94 350.5 Lactobacillaceae ygfC Bacteria 1V4D3@1239,3F6ZM@33958,4HJ8Z@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family GHBLAFEN_02162 405566.lhv_1881 1.2e-111 409.1 Lactobacillaceae Bacteria 1V6ES@1239,3F5SD@33958,4HGZI@91061,COG0406@1,COG0406@2 NA|NA|NA G phosphoglycerate mutase GHBLAFEN_02163 1423748.BALB01000012_gene1250 6.6e-139 500.0 Lactobacillaceae aroD ko:K06889 ko00000 Bacteria 1V43W@1239,3F4SI@33958,4HNBU@91061,COG1073@1,COG1073@2 NA|NA|NA S Alpha/beta hydrolase family GHBLAFEN_02164 405566.lhv_1883 6.4e-142 510.0 Lactobacillaceae ko:K09861 ko00000 Bacteria 1TR33@1239,3F4KR@33958,4HFN2@91061,COG3022@1,COG3022@2 NA|NA|NA S Belongs to the UPF0246 family GHBLAFEN_02165 326425.lhe_0334 1.2e-120 439.1 Lactobacillaceae Bacteria 1U59M@1239,2CBCD@1,309KB@2,3F5A8@33958,4IF11@91061 NA|NA|NA GHBLAFEN_02166 1423748.BALB01000012_gene1253 3.1e-49 200.7 Lactobacillaceae 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSNU@1239,3F3JH@33958,4H9TY@91061,COG1085@1,COG1085@2 NA|NA|NA C Domain of unknown function (DUF4931) GHBLAFEN_02167 405566.lhv_1631 4.3e-52 210.3 Lactobacillaceae ko:K07473 ko00000,ko02048 Bacteria 1VGJW@1239,3F6PK@33958,4HR7A@91061,COG3077@1,COG3077@2 NA|NA|NA L RelB antitoxin GHBLAFEN_02168 326425.lhe_1511 4.8e-141 507.3 Lactobacillaceae qmcA GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 Bacteria 1TPXU@1239,3F4HV@33958,4HGRC@91061,COG0330@1,COG0330@2 NA|NA|NA O prohibitin homologues GHBLAFEN_02169 326425.lhe_1510 7.5e-123 446.4 Lactobacillaceae darA Bacteria 1V45R@1239,3F7P2@33958,4HQY8@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin GHBLAFEN_02170 891391.LAC30SC_08480 1.3e-309 1068.1 Lactobacillaceae fhs GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP6N@1239,3F3U6@33958,4HA2X@91061,COG2759@1,COG2759@2 NA|NA|NA F Belongs to the formate--tetrahydrofolate ligase family GHBLAFEN_02171 1423767.BALU01000011_gene265 4.2e-78 297.4 Lactobacillaceae purE GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551 Bacteria 1V1MV@1239,3F6P0@33958,4HFR7@91061,COG0041@1,COG0041@2 NA|NA|NA F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) GHBLAFEN_02172 1423767.BALU01000011_gene266 1.1e-217 762.3 Lactobacillaceae purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQCD@1239,3F3YV@33958,4H9M5@91061,COG0026@1,COG0026@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) GHBLAFEN_02173 891391.LAC30SC_08460 3.9e-133 480.7 Lactobacillaceae purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016881,GO:0044424,GO:0044444,GO:0044464 4.1.1.21,4.3.2.2,6.3.2.6 ko:K01587,ko:K01756,ko:K01923 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04209,R04559,R04591 RC00064,RC00162,RC00379,RC00444,RC00445,RC00590 ko00000,ko00001,ko00002,ko01000 iAF1260.b2476,iB21_1397.B21_02330,iBWG_1329.BWG_2240,iE2348C_1286.E2348C_2713,iEC042_1314.EC042_2677,iEC55989_1330.EC55989_2759,iECABU_c1320.ECABU_c27880,iECBD_1354.ECBD_1213,iECB_1328.ECB_02368,iECDH10B_1368.ECDH10B_2642,iECDH1ME8569_1439.ECDH1ME8569_2402,iECDH1ME8569_1439.EcDH1_1193,iECD_1391.ECD_02368,iECED1_1282.ECED1_2911,iECH74115_1262.ECH74115_3698,iECIAI1_1343.ECIAI1_2527,iECNA114_1301.ECNA114_2561,iECO103_1326.ECO103_2988,iECO111_1330.ECO111_3199,iECO26_1355.ECO26_3522,iECOK1_1307.ECOK1_2784,iECP_1309.ECP_2490,iECS88_1305.ECS88_2658,iECSE_1348.ECSE_2760,iECSF_1327.ECSF_2329,iECSP_1301.ECSP_3415,iECUMN_1333.ECUMN_2789,iECW_1372.ECW_m2698,iECs_1301.ECs3338,iEKO11_1354.EKO11_1259,iETEC_1333.ETEC_2581,iEcDH1_1363.EcDH1_1193,iEcE24377_1341.EcE24377A_2757,iEcHS_1320.EcHS_A2607,iEcSMS35_1347.EcSMS35_2623,iEcolC_1368.EcolC_1200,iG2583_1286.G2583_2999,iJN746.PP_1240,iJO1366.b2476,iJR904.b2476,iLF82_1304.LF82_1775,iNRG857_1313.NRG857_12360,iSFV_1184.SFV_2521,iSF_1195.SF2519,iSFxv_1172.SFxv_2773,iS_1188.S2669,iSbBS512_1146.SbBS512_E2848,iUMNK88_1353.UMNK88_3071,iWFL_1372.ECW_m2698,iY75_1357.Y75_RS12925,iYL1228.KPN_02810,iZ_1308.Z3735 Bacteria 1TP11@1239,3F44Z@33958,4H9U8@91061,COG0152@1,COG0152@2 NA|NA|NA F Belongs to the SAICAR synthetase family GHBLAFEN_02174 891391.LAC30SC_08455 1.9e-37 161.4 Lactobacillaceae purS 6.3.2.6,6.3.5.3 ko:K01923,ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463,R04591 RC00010,RC00064,RC00162,RC01160 ko00000,ko00001,ko00002,ko01000 iYO844.BSU06460 Bacteria 1VEH1@1239,3F81F@33958,4HP0E@91061,COG1828@1,COG1828@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL GHBLAFEN_02175 891391.LAC30SC_08450 2.3e-119 434.9 Lactobacillaceae purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1B@1239,3F48D@33958,4HAKZ@91061,COG0047@1,COG0047@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL GHBLAFEN_02176 891391.LAC30SC_08445 0.0 1488.0 Lactobacillaceae purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAS@1239,3F4IQ@33958,4HB3N@91061,COG0046@1,COG0046@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL GHBLAFEN_02177 891391.LAC30SC_08440 1.5e-275 954.9 Lactobacillaceae purF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 iSB619.SA_RS05225 Bacteria 1TPH3@1239,3F3U7@33958,4HAXU@91061,COG0034@1,COG0034@2 NA|NA|NA F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine GHBLAFEN_02178 891391.LAC30SC_08435 2.3e-195 688.0 Lactobacillaceae purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 ko:K01933,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1844,iECSF_1327.ECSF_2340 Bacteria 1TP9J@1239,3F4RT@33958,4HABW@91061,COG0150@1,COG0150@2 NA|NA|NA F Phosphoribosylformylglycinamidine cyclo-ligase GHBLAFEN_02179 891391.LAC30SC_08430 3.2e-104 384.4 Lactobacillaceae purN 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3RJ@1239,3F3UN@33958,4HGY5@91061,COG0299@1,COG0299@2 NA|NA|NA F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate GHBLAFEN_02180 891391.LAC30SC_08425 3.2e-289 1000.3 Lactobacillaceae purH GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.purH Bacteria 1TPQ5@1239,3F4FD@33958,4H9YY@91061,COG0138@1,COG0138@2 NA|NA|NA F Bifunctional purine biosynthesis protein PurH GHBLAFEN_02181 585524.HMPREF0493_0471 2.3e-237 827.8 Lactobacillaceae purD 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS05245,iYO844.BSU06530 Bacteria 1UHN9@1239,3F4Z8@33958,4HA70@91061,COG0151@1,COG0151@2 NA|NA|NA F Belongs to the GARS family GHBLAFEN_02182 405566.lhv_1623 0.0 1658.3 Lactobacillaceae cas3 ko:K07012 ko00000,ko01000,ko02048 Bacteria 1TQ9B@1239,3F5AQ@33958,4HC62@91061,COG1203@1,COG1203@2 NA|NA|NA L Type III restriction enzyme, res subunit GHBLAFEN_02183 405566.lhv_1622 1.1e-143 515.8 Lactobacillaceae cas5d ko:K19119 ko00000,ko02048 Bacteria 1TPSR@1239,2DBAF@1,2Z82V@2,3F5SY@33958,4HCZQ@91061 NA|NA|NA S CRISPR-associated protein (Cas_Cas5) GHBLAFEN_02184 405566.lhv_1621 0.0 1323.5 Lactobacillaceae csd1 3.5.1.28 ko:K01447,ko:K17733,ko:K19117 R04112 RC00064,RC00141 ko00000,ko01000,ko01002,ko01011,ko02048 Bacteria 1TR9V@1239,3F5CZ@33958,4HDQB@91061,COG5632@1,COG5632@2 NA|NA|NA M CRISPR-associated protein (Cas_Csd1) GHBLAFEN_02185 405566.lhv_1620 9.3e-158 562.8 Lactobacillaceae csd2 ko:K19115,ko:K19118 ko00000,ko02048 Bacteria 1TQZ8@1239,3F5S4@33958,4H9KH@91061,COG3649@1,COG3649@2 NA|NA|NA L CRISPR-associated protein Cas7 GHBLAFEN_02186 405566.lhv_1619 2.8e-125 454.5 Lactobacillaceae cas4 3.1.12.1 ko:K07464,ko:K15342 ko00000,ko01000,ko02048,ko03400 Bacteria 1TT4D@1239,3F64R@33958,4HEH3@91061,COG1468@1,COG1468@2 NA|NA|NA L Domain of unknown function DUF83 GHBLAFEN_02187 405566.lhv_1618 2.9e-198 697.6 Lactobacillaceae cas1 ko:K15342 ko00000,ko02048,ko03400 Bacteria 1TQWG@1239,3F5RS@33958,4H9SJ@91061,COG1518@1,COG1518@2 NA|NA|NA L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette GHBLAFEN_02188 334390.LAF_1208 1.4e-28 132.1 Lactobacillaceae cas2 GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K09951 ko00000,ko02048 Bacteria 1VAV3@1239,3F8MC@33958,4HP0S@91061,COG1343@1,COG1343@2 NA|NA|NA L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette GHBLAFEN_02189 525365.HMPREF0548_2172 9e-14 82.0 Lactobacillaceae Bacteria 1VIEC@1239,2EC9R@1,33683@2,3F7A0@33958,4HSN3@91061 NA|NA|NA GHBLAFEN_02190 405566.lhv_1617 0.0 1699.5 Lactobacillaceae polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1TPKJ@1239,3F3ZA@33958,4H9S7@91061,COG0258@1,COG0258@2,COG0749@1,COG0749@2 NA|NA|NA L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity GHBLAFEN_02191 326425.lhe_1494 7.7e-157 559.7 Lactobacillaceae fpg 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPM9@1239,3F43E@33958,4H9Q7@91061,COG0266@1,COG0266@2 NA|NA|NA L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates GHBLAFEN_02192 326425.lhe_1493 1.4e-104 385.6 Lactobacillaceae coaE 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6FS@1239,3F6WF@33958,4HII3@91061,COG0237@1,COG0237@2 NA|NA|NA F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A GHBLAFEN_02193 326425.lhe_1492 4.1e-83 313.9 Lactobacillaceae nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K07738 ko00000,ko03000 Bacteria 1V3JA@1239,3F65S@33958,4HGXA@91061,COG1327@1,COG1327@2 NA|NA|NA K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes GHBLAFEN_02194 326425.lhe_1491 9.8e-247 859.0 Lactobacillaceae dnaB ko:K03346 ko00000,ko03032 Bacteria 1TSBB@1239,3FB6I@33958,4HE63@91061,COG3611@1,COG3611@2 NA|NA|NA L Replication initiation and membrane attachment GHBLAFEN_02195 326425.lhe_1490 4.5e-166 590.5 Lactobacillaceae dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K11144 ko00000,ko03032 Bacteria 1TPZX@1239,3F4JK@33958,4HABS@91061,COG1484@1,COG1484@2 NA|NA|NA L Primosomal protein DnaI GHBLAFEN_02196 405566.lhv_1611 0.0 1283.1 Lactobacillaceae thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP78@1239,3F3TC@33958,4HABZ@91061,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) GHBLAFEN_02197 326425.lhe_1488 1.6e-88 332.0 Lactobacillaceae Bacteria 1U68M@1239,29NRA@1,30A5W@2,3F7B3@33958,4IFZH@91061 NA|NA|NA GHBLAFEN_02198 405566.lhv_1609 4.1e-95 354.0 Lactobacillaceae Bacteria 1U5FC@1239,29NRA@1,309P8@2,3F5US@33958,4IF6Y@91061 NA|NA|NA GHBLAFEN_02199 326425.lhe_1484 1.4e-178 632.5 Lactobacillaceae Bacteria 1TRFZ@1239,3F4KN@33958,4HEZ0@91061,COG1808@1,COG1808@2 NA|NA|NA S Domain of unknown function (DUF389) GHBLAFEN_02200 891391.LAC30SC_08330 9.3e-30 136.0 Lactobacillaceae astA 2.8.2.22 ko:K01023 ko00000,ko01000 Bacteria 1TSWC@1239,28MBK@1,2ZAQ1@2,3F50E@33958,4HCSW@91061 NA|NA|NA M Arylsulfotransferase Ig-like domain GHBLAFEN_02201 1423748.BALB01000003_gene394 2.5e-155 554.7 Lactobacillaceae astA 2.8.2.22 ko:K01023 ko00000,ko01000 Bacteria 1TSWC@1239,28MBK@1,2ZAQ1@2,3F50E@33958,4HCSW@91061 NA|NA|NA M Arylsulfotransferase Ig-like domain GHBLAFEN_02202 1423748.BALB01000003_gene394 8.9e-37 159.1 Lactobacillaceae astA 2.8.2.22 ko:K01023 ko00000,ko01000 Bacteria 1TSWC@1239,28MBK@1,2ZAQ1@2,3F50E@33958,4HCSW@91061 NA|NA|NA M Arylsulfotransferase Ig-like domain GHBLAFEN_02203 405566.lhv_1598 1.8e-54 218.4 Lactobacillaceae infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 1V1RC@1239,3F4MS@33958,4HFUS@91061,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins GHBLAFEN_02204 1423748.BALB01000003_gene396 1.8e-27 127.9 Lactobacillaceae rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02916 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VF5W@1239,3F7CQ@33958,4HNIQ@91061,COG0291@1,COG0291@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL35 family GHBLAFEN_02205 1423767.BALU01000009_gene397 5.1e-57 226.9 Lactobacillaceae rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6DB@1239,3F6HZ@33958,4HH2W@91061,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit GHBLAFEN_02206 405566.lhv_1595 3.8e-93 347.4 Lactobacillaceae yqeG ko:K07015 ko00000 Bacteria 1V6KM@1239,3F46V@33958,4HGAV@91061,COG2179@1,COG2179@2 NA|NA|NA S HAD phosphatase, family IIIA GHBLAFEN_02207 405566.lhv_1594 3.6e-210 737.3 Lactobacillaceae yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 ko:K06948 ko00000,ko03009 Bacteria 1TPM2@1239,3F4JU@33958,4HAAF@91061,COG1161@1,COG1161@2 NA|NA|NA S Ribosome biogenesis GTPase YqeH GHBLAFEN_02208 326425.lhe_1476 8.3e-122 443.0 Lactobacillaceae nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1V3SK@1239,3F4D6@33958,4HGXK@91061,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) GHBLAFEN_02209 326425.lhe_1475 2.3e-110 404.8 Lactobacillaceae nadD 2.7.6.3,2.7.7.18 ko:K00950,ko:K00969,ko:K06950 ko00760,ko00790,ko01100,map00760,map00790,map01100 M00115,M00126,M00841 R00137,R03005,R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6Y1@1239,3F47C@33958,4HHRY@91061,COG1713@1,COG1713@2 NA|NA|NA H Hydrolase, HD family GHBLAFEN_02210 326425.lhe_1474 6.9e-59 233.0 Lactobacillaceae rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 ko:K09710 ko00000,ko03009 Bacteria 1VA2Z@1239,3F7QN@33958,4HKEJ@91061,COG0799@1,COG0799@2 NA|NA|NA J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation GHBLAFEN_02211 326425.lhe_1473 6.6e-215 753.1 Lactobacillaceae ylbM Bacteria 1TPP2@1239,3F3QC@33958,4HAZJ@91061,COG1323@1,COG1323@2 NA|NA|NA S Belongs to the UPF0348 family GHBLAFEN_02212 405566.lhv_1589 1e-96 359.4 Lactobacillaceae yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K07040 ko00000 Bacteria 1VB08@1239,3F61Z@33958,4HME9@91061,COG1399@1,COG1399@2 NA|NA|NA S Uncharacterized ACR, COG1399 GHBLAFEN_02213 326425.lhe_1471 3.2e-127 461.1 Lactobacillaceae Bacteria 1TS81@1239,3F421@33958,4H9NE@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator GHBLAFEN_02214 326425.lhe_1470 1e-279 968.8 Lactobacillaceae arlS GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K18940 ko02020,map02020 M00716,M00717 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TPSK@1239,3F3NU@33958,4HAH5@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase GHBLAFEN_02215 326425.lhe_1346 1.5e-199 701.8 Lactobacillaceae ilvE 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TQQI@1239,3F4BD@33958,4HASX@91061,COG0115@1,COG0115@2 NA|NA|NA E Branched-chain amino acid aminotransferase GHBLAFEN_02216 326425.lhe_1347 4.7e-128 463.8 Lactobacillaceae Bacteria 1VBTT@1239,2E7EK@1,331XM@2,3F4W0@33958,4HMT5@91061 NA|NA|NA S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) GHBLAFEN_02217 1033837.WANG_0371 2.1e-27 127.5 Lactobacillaceae dmpI GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 Bacteria 1VKD5@1239,3F83T@33958,4HRBS@91061,COG1942@1,COG1942@2 NA|NA|NA G Belongs to the 4-oxalocrotonate tautomerase family GHBLAFEN_02218 405566.lhv_1432 0.0 1091.3 Lactobacillaceae Bacteria 1TS3Q@1239,3F4AT@33958,4HF7D@91061,COG4907@1,COG4907@2 NA|NA|NA S Predicted membrane protein (DUF2207) GHBLAFEN_02219 405566.lhv_1433 4.8e-200 703.7 Lactobacillaceae ko:K07273 ko00000 Bacteria 1VF8D@1239,3F4U9@33958,4HX0U@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 GHBLAFEN_02221 748671.LCRIS_01023 2.4e-154 552.4 Lactobacillaceae Bacteria 1TSRV@1239,3F3JJ@33958,4HIAU@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region GHBLAFEN_02223 1033837.WANG_1440 2.6e-244 850.9 Lactobacillaceae eno2 GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0043236,GO:0050840 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 1V12I@1239,3FCCA@33958,4HTD2@91061,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis GHBLAFEN_02224 1423758.BN55_04385 1.1e-159 569.3 Lactobacillaceae ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 1U59Y@1239,3F5BK@33958,4IF1G@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family GHBLAFEN_02225 405566.lhv_2045 6.2e-211 740.0 Lactobacillaceae pts13C ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 Bacteria 1V5SI@1239,3F3Z5@33958,4HJTK@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane GHBLAFEN_02226 405566.lhv_2044 6e-157 560.1 Lactobacillaceae Bacteria 1V8NG@1239,3F41V@33958,4HJ22@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF915) GHBLAFEN_02227 405566.lhv_2043 0.0 1347.8 Lactobacillaceae clpE ko:K03697 ko00000,ko03110 Bacteria 1TPMU@1239,3F5GX@33958,4HA0V@91061,COG0542@1,COG0542@2 NA|NA|NA O AAA domain (Cdc48 subfamily) GHBLAFEN_02228 326425.lhe_0218 4.9e-119 433.7 Lactobacillaceae lepB 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1TRAV@1239,3FBKX@33958,4HCTU@91061,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family GHBLAFEN_02229 326425.lhe_0535 5.6e-135 486.9 Lactobacillaceae tagA 2.4.1.187 ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 GT26 Bacteria 1V3QV@1239,3F4WB@33958,4HH6B@91061,COG1922@1,COG1922@2 NA|NA|NA F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid GHBLAFEN_02230 326425.lhe_0536 5.9e-205 719.9 Lactobacillaceae csaB Bacteria 1UHSF@1239,3F428@33958,4HB04@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 GHBLAFEN_02231 326425.lhe_0537 5.2e-281 973.0 Lactobacillaceae pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 iYO844.BSU31750 Bacteria 1TPDW@1239,3F3K7@33958,4HAI4@91061,COG1488@1,COG1488@2 NA|NA|NA F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP GHBLAFEN_02232 326425.lhe_0538 6.1e-154 550.1 Lactobacillaceae nadE GO:0003674,GO:0003824,GO:0003952,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0033554,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_1910,iECW_1372.ECW_m1909,iEKO11_1354.EKO11_2035,iETEC_1333.ETEC_1772,iEcE24377_1341.EcE24377A_1961,iSFV_1184.SFV_1480,iSF_1195.SF1486,iSFxv_1172.SFxv_1676,iSSON_1240.SSON_1418,iS_1188.S1603,iWFL_1372.ECW_m1909 Bacteria 1TQ38@1239,3F43Z@33958,4HA2R@91061,COG0171@1,COG0171@2 NA|NA|NA F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source GHBLAFEN_02233 748671.LCRIS_00061 3.4e-78 297.7 Firmicutes Bacteria 1VGFB@1239,2DPM9@1,332MQ@2 NA|NA|NA GHBLAFEN_02236 545697.HMPREF0216_01143 1.9e-22 112.1 Firmicutes Bacteria 1UM1X@1239,28KRP@1,2ZA95@2 NA|NA|NA GHBLAFEN_02237 13035.Dacsa_0012 5.4e-07 60.1 Cyanobacteria 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 ko00000,ko01000,ko02048 Bacteria 1G911@1117,COG0863@1,COG0863@2,COG2189@1,COG2189@2 NA|NA|NA L Belongs to the N(4) N(6)-methyltransferase family GHBLAFEN_02238 906968.Trebr_0084 1.9e-34 151.8 Spirochaetes 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 ko00000,ko01000,ko02048 Bacteria 2J9BG@203691,COG0863@1,COG0863@2,COG2189@1,COG2189@2 NA|NA|NA L Belongs to the N(4) N(6)-methyltransferase family GHBLAFEN_02239 1423748.BALB01000003_gene495 6.4e-40 169.5 Lactobacillaceae Bacteria 1VB5V@1239,3F3P4@33958,4HN9W@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family GHBLAFEN_02240 1423748.BALB01000003_gene495 2.5e-33 147.5 Lactobacillaceae Bacteria 1VB5V@1239,3F3P4@33958,4HN9W@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family GHBLAFEN_02241 1423748.BALB01000022_gene1676 7e-93 346.7 Lactobacillaceae Bacteria 1V7GB@1239,3F5VT@33958,4I28M@91061,COG4990@1,COG4990@2 NA|NA|NA G Peptidase_C39 like family GHBLAFEN_02242 1423748.BALB01000003_gene493 3e-26 124.0 Lactobacillaceae Bacteria 1U6VF@1239,2CKSK@1,31Y2F@2,3F8JR@33958,4IGPC@91061 NA|NA|NA GHBLAFEN_02243 1133569.AHYZ01000050_gene233 2.9e-32 145.2 Bacilli ko:K03523 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 Bacteria 1VAY6@1239,4HHJM@91061,COG1268@1,COG1268@2 NA|NA|NA S Biotin synthase GHBLAFEN_02244 525365.HMPREF0548_1256 1.1e-28 132.1 Lactobacillaceae ko:K18843 ko00000,ko02048 Bacteria 1VAII@1239,3F8YB@33958,4HM80@91061,COG1598@1,COG1598@2 NA|NA|NA S HicB family GHBLAFEN_02247 326425.lhe_1028 4.8e-60 236.9 Lactobacillaceae yafQ GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006415,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032984,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034655,GO:0042221,GO:0042710,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043565,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044010,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044764,GO:0044877,GO:0046483,GO:0046677,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 ko:K19157 ko00000,ko01000,ko02048 Bacteria 1U6BU@1239,3F7JG@33958,4IG3F@91061,COG3041@1,COG3041@2 NA|NA|NA S Bacterial toxin of type II toxin-antitoxin system, YafQ GHBLAFEN_02248 326425.lhe_1027 4.6e-45 186.8 Lactobacillaceae yefM 2.3.1.15 ko:K08591,ko:K19158,ko:K19159 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004,ko02048 Bacteria 1U6CD@1239,3F7KJ@33958,4IG41@91061,COG2161@1,COG2161@2 NA|NA|NA D Antitoxin component of a toxin-antitoxin (TA) module GHBLAFEN_02249 748671.LCRIS_01419 4.9e-86 324.3 Lactobacillaceae Bacteria 1TSFX@1239,3F4R3@33958,4HGAF@91061,COG2253@1,COG2253@2 NA|NA|NA S Nucleotidyl transferase AbiEii toxin, Type IV TA system GHBLAFEN_02250 1033837.WANG_p1028 1.9e-96 358.6 Lactobacillaceae Bacteria 1V3JU@1239,3F608@33958,4HMVW@91061,COG5340@1,COG5340@2 NA|NA|NA K Transcriptional regulator, AbiEi antitoxin GHBLAFEN_02251 326425.lhe_1108 3.8e-84 317.8 Lactobacillaceae ko:K04763 ko00000,ko03036 Bacteria 1V2RX@1239,3F4SP@33958,4IEJ7@91061,COG0582@1,COG0582@2 NA|NA|NA L Integrase GHBLAFEN_02252 743525.TSC_c13790 8.1e-28 132.1 Bacteria Bacteria COG1520@1,COG1520@2 NA|NA|NA S amino acid activation for nonribosomal peptide biosynthetic process GHBLAFEN_02253 326425.lhe_1245 2.4e-74 284.6 Lactobacillaceae Bacteria 1U5E5@1239,2AJU9@1,31AGT@2,3F5PH@33958,4IF5F@91061 NA|NA|NA GHBLAFEN_02254 326425.lhe_1246 5.9e-106 390.2 Lactobacillaceae Bacteria 1TT5B@1239,3F6BZ@33958,4HK1M@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain GHBLAFEN_02255 326425.lhe_1247 2.5e-19 100.5 Lactobacillaceae Bacteria 1U6K3@1239,2CETM@1,30AF4@2,3F82Q@33958,4IGCS@91061 NA|NA|NA GHBLAFEN_02256 405566.lhv_1311 3.1e-212 744.2 Lactobacillaceae Bacteria 1V7PR@1239,3FBA9@33958,4HV9V@91061,COG4552@1,COG4552@2 NA|NA|NA S Sterol carrier protein domain GHBLAFEN_02257 525318.HMPREF0497_2714 1.1e-130 472.6 Lactobacillaceae Bacteria 1TSZZ@1239,3F49K@33958,4HB54@91061,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase GHBLAFEN_02258 1423780.LOT_0174 1.9e-113 415.2 Lactobacillaceae pgmB GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008801,GO:0009058,GO:0009292,GO:0009294,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016853,GO:0016866,GO:0016868,GO:0019203,GO:0030312,GO:0033554,GO:0034637,GO:0040007,GO:0042221,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046351,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0071704,GO:0071944,GO:1901576 2.4.1.64,3.1.3.12,3.2.1.28,5.4.2.6 ko:K01087,ko:K01194,ko:K01838,ko:K05342 ko00500,ko01100,map00500,map01100 R00010,R02727,R02728,R02778,R11310 RC00017,RC00049,RC00408 ko00000,ko00001,ko00537,ko01000 GH37,GH65 Bacteria 1UY8N@1239,3F4ST@33958,4HF3K@91061,COG0637@1,COG0637@2 NA|NA|NA S beta-phosphoglucomutase GHBLAFEN_02259 511437.Lbuc_1257 0.0 1593.9 Lactobacillaceae trePP GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0030312,GO:0044464,GO:0071944 2.4.1.216,2.4.1.8,3.1.3.12,3.2.1.28 ko:K00691,ko:K01087,ko:K01194,ko:K03731 ko00500,ko01100,map00500,map01100 R00010,R01555,R02778 RC00017,RC00049 ko00000,ko00001,ko00537,ko01000 GH37,GH65 Bacteria 1TQMB@1239,3F4TB@33958,4HD7Z@91061,COG1554@1,COG1554@2 NA|NA|NA G Glycosyl hydrolase family 65 central catalytic domain GHBLAFEN_02260 1033837.WANG_1183 1.1e-44 185.7 Lactobacillaceae uvrX 2.7.7.7 ko:K02346,ko:K03502,ko:K14161 ko00000,ko01000,ko03400 Bacteria 1TP42@1239,3F3WN@33958,4HA1P@91061,COG0389@1,COG0389@2 NA|NA|NA L Belongs to the DNA polymerase type-Y family GHBLAFEN_02261 97137.C821_00559 2.6e-117 428.7 Lactobacillaceae Bacteria 1UI8W@1239,3F6SG@33958,4ISGD@91061,COG3152@1,COG3152@2 NA|NA|NA S Membrane GHBLAFEN_02262 97137.C821_00560 4e-107 394.8 Lactobacillaceae Bacteria 1VZSI@1239,29W71@1,30HS8@2,3F4M9@33958,4IEVP@91061 NA|NA|NA S Domain of unknown function (DUF4767) # 2115 queries scanned # Total time (seconds): 4.60964083672 # Rate: 458.82 q/s