LOCUS       c00045_JABURW0..       12838 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JABURW010000039.1 Lacticaseibacillus rhamnosus strain OSU-PECh-69
            k99_626, whole genome shotgun sequence.
ACCESSION   JABURW010000039
VERSION     JABURW010000039
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2022-06-21 10:12:16
            Original ID  :: JABURW010000039.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 251328
            Orig. end    :: 264166
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12838
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[261328:263386]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Flavoprotein,
                     Semialdhyde_dh]) and gallic_acid)"
                     /neighbourhood="10000"
                     /product="gallic_acid_met"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12058
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Flavoprotein,
                     Semialdhyde_dh]) and gallic_acid)"
                     /neighbourhood="10000"
                     /product="gallic_acid_met"
                     /protocluster_number="1"
     cand_cluster    1..12838
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [Flavoprotein,
                     Semialdhyde_dh]) and gallic_acid)"
                     /kind="single"
                     /product="gallic_acid_met"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12838
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="gallic_acid_met"
                     /region_number="1"
                     /rules="(minimum(1, [Flavoprotein, Semialdhyde_dh]) and
                     gallic_acid)"
                     /tool="gutsmash"
     CDS             complement(443..1237)
                     /locus_tag="ctg45_231"
                     /transl_table=11
                     /translation="MSQSPAKFERLNEIIQILRETPEISIAQLSKRMFTSKSTLRRDLI
                     ELENSNIIRRHYGTVQLLQGNNLEFTYEKRRNENARLKRVISRQIAAKIPSNAAFFIDG
                     SSTFFSLPELLHEQVGLHVITNNVNMGMQFNSLNNVETIILGGKMAPRTASTLGATTIN
                     EIQSFRPDFALLSIGSIDADGIYVADPEQAAVKEAMIAAAKCVILGIDSTKFNQSDYIR
                     ITNMDQISEIITDTQPAPEYGNLFDDHHIQLTYPKAHHHLAD"
     CDS             1443..1922
                     /locus_tag="ctg45_232"
                     /transl_table=11
                     /translation="MDYSTMIHKQLIFLNENQPDRQHLFRAVAEKLQAAGYVKKTYEAA
                     LNRREDEFPTGIVFPEISVMLPHADPEHVIKPFMAIVKNAQPVRVLQMGYNEPEDATAM
                     FFLGITDSSQQVGLLQIFMDLLQNQDFVAKFKATNDRDAMYQLFVDTFEAQTTGK"
     CDS             1944..2264
                     /locus_tag="ctg45_233"
                     /transl_table=11
                     /translation="MAKIVVACGSGVASSEATASRIKDFFESHNVKGVSVDATDFKQLP
                     EVLHNYDVYVWIAKPNQQLEELAKENNIAVVNGMPIFMNMNPEKSYKQIIQALKNMQAA
                     GK"
     CDS             2337..3905
                     /locus_tag="ctg45_234"
                     /transl_table=11
                     /translation="VTILKDVVNYILNLGGPVFVPLIMLILGLVAGLKFKKSIVAALTL
                     GVAFSGMTLVVNYMMDAISPAAKAMSKLFHLSLNAIDAGWTGVAAITWSYKSAFLFFPL
                     LLAINFVMLTFNWTKTLNVDMWNVWNKIFTYVVVLYFTHNAFFGFLVAGIQIVFELKAG
                     DMWHRHIEDLTGMPGVTVPHFITLFAVILQPLNKLLDFIPIMNKPFDADALQKRIGVWG
                     DNTVMGALIGVLLGFGAGYSVSGSLNLAIKAATAMTLFPMISKLFMTALSPIADAMSGF
                     MQKHFKGREVYIGLDWPILAGRNELWVTVIILVPIMLVFAMILPHNTVLPFAGIINLSF
                     VNAALLLTGANLLRMITLGIITTPIFLYGATYFAPVITNLAKSTGTVKVQAGQQLSWST
                     FEGPDFRLFFAQAFNGKWWAIALAVLWTLGFIWLYRDQNKIKLPSQRYGTLTTPALATT
                     SSTSAADSADADIDLDNLSGLDFSDAKASNESQQSDAKNDDDLDDLGGLDFSQTSHKKK
                     GDQGE"
     CDS             3898..4134
                     /locus_tag="ctg45_235"
                     /transl_table=11
                     /translation="VSKTLASFLVFIDTIGVSIALLGGSVGLCLLMGLVTIVLYSKVNP
                     VLFGDYDRKRRERINQRRKELLAQRVKNGGFSK"
     CDS             4131..4859
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldolase_II"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_236"
                     /sec_met_domain="Aldolase_II (E-value: 1.2e-30, bitscore:
                     100.8, seeds: 389, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEQYVFENERKDLAEVAREMFVRKNTNVAGGNISVRITADKDID
                     YGSIHIKAGKDYLIMTPTMMSEAWYAKLQPTQILVVDLETGKQIDGVGRLTREINMHEE
                     AYRANDKIRCVYHSHAEESMFWATAGLDMPNVTEVTEEVGPIRVLPYAPACSKELADTV
                     YNGLKAVGDAAKEHIFLLNSHGVLITSEDLHHATEILETVEWNAKIAYQQTVFMKLGLL
                     DSYQSCGKASDGMLKEQVQA"
     CDS             complement(5092..6474)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 143.3; E-value: 2.9e-44)"
                     /gene_kind="transport"
                     /locus_tag="ctg45_237"
                     /sec_met_domain="MFS_1 (E-value: 1.1e-43, bitscore: 143.3,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRKVTPKLYLSILATGLMAFCGVLIETAMNVTFPTLMRQFNVDT
                     GTIQWLTTGYLLIVAIIVPISGFLKRRFTTKQLFLTASAFFILGLALCSVANSFAILLV
                     GRLIQGCGTGIALPLMFNIILEQAPLEKIGFLMGIGTLVTAIAPALGPTYGGVLVDINW
                     HLIFIFLLFVMIAALIMGLFSIQQVSETVHLHLDFLAWLFIAIFFATAILGLNSIEHQP
                     GRALIFAVIAILSLGAYTMRSLHVKEPLINLRLFKNLPFDLHMTTFLIIQIVNVGFAFV
                     LPNYLQLVNHTSSLTAGLLLLPGAALGACMAPMSGKLYDKLGPGRPIFIGLCLQLIGII
                     WLLLEALTAAPVIVLIGYAFIMLGTGFSMGNIMTSGQAQLHQEQTTDGNAIFNTLQQFA
                     GALGTAVVSLIMALAQAGSTSAHNTAIGSQHAFGFLLLLTLIGDVAIFFGLRRRHGETT
                     GK"
     CDS             6607..7044
                     /locus_tag="ctg45_238"
                     /transl_table=11
                     /translation="VTVSLGILVKKLNNDLQRYADREAKQLGLTQVQMSIIDFLARQGT
                     KRPLYQTDVEHEFNIQKSSATALLQLMERKELIVRVPSKQDGRYKAIQLTEKSQKVAAY
                     IRHFFDQNDAFLRNALGEDAEVVVNALEKLQTTMAAKLADH"
     CDS             complement(7107..7538)
                     /locus_tag="ctg45_239"
                     /transl_table=11
                     /translation="MSDYPVPTYTTTVTQSDVTLIATVTVIGRDLLITITGGDHPHIGD
                     VLTLTKDQPIQTIRYPSHDNRFHKDDLLALPSAKALQPLLPGSCTILAGLHIDHISKVQ
                     IQAALDLSHKLAPKLTTWLKHQTFATSRPHYYGPDESPA"
     CDS             7568..8467
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     61.9; E-value: 1.4e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg45_240"
                     /sec_met_domain="LysR_substrate (E-value: 4.9e-31,
                     bitscore: 101.6, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 5.5e-19, bitscore: 61.9,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNFEDLKIFVALYELKSFSKAAVVLHLSQSALSKRIQHIEAILGS
                     KLVDTSNHRRMLVTEAGERFFFHASKILHQVELMNTDLNSLKSLSNGVLTIGAVPILGQ
                     FGISRLINDFAAQFPKLALHVVEQEGISILKQLLTGDLDMALLRDTQAEVLSTREYVKL
                     DLAKDELQVILAKTNPLAKRPSLSANNLAATTIVSLLSGSGVFEPMQAFFADRHIAPKI
                     IFSSPHIETLLGMVEGSRHVTFLFRQSYQPFANSNFVAKSLTPNICSHLQLVYRRTSNP
                     AILKFADYLSQQVTAEKG"
     CDS             complement(8613..10004)
                     /locus_tag="ctg45_241"
                     /transl_table=11
                     /translation="MKKVLNKQNIGFLIGIAVGLIVYLAPLSGINEKAQMDLTLSLMTV
                     VWWAFQIAQPAYIGGIYLMLLILTNVATPTQVFAGSWTKSIMWLVMGAYLIAGAVRESG
                     LGERIAYAFIIKFVRSWTGIIVSIFALTFILALLIPHPWPRAFLIMSVMDVVATSAKMP
                     QQDRAKLGLAVFAASCPLSGAFLTGDTSLNPLAIADSGKSVNFVQYFIYMGVPMIIAAI
                     ITMLLFLFLFKPTKKVTIDLDVLKAKQADQGAMTHKEIRVIVWLVIAIGLWLTSGITGI
                     DVGWLTLIVALLMSLPVIGEVLTAKSWSGVPVNVLVFLTSAIAIGQVGDFTGMNKWIAQ
                     TILPSALPHNLYLLALVITVFAMIIHMFMGSVIAVMGITIPAIIAATSSLGVNPLAISL
                     IVFSVVNLHYILPFHNLAILVGSDPETGGGYTQKDVMKLGIPLTAVMFIVALVEVFWFQ
                     LTGLL"
     CDS             complement(10001..10573)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     gallic_acid_met: Flavoprotein"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_242"
                     /sec_met_domain="Flavoprotein (E-value: 7.5e-30, bitscore:
                     97.7, seeds: 91, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKRIIVGITGASGTIYAVNLLQHLHRLPDVEVHLVMSAWAKQNLS
                     LETDMKQSELEALADYVYPVQNQGATIASGSFLTDAMVIVPASMKTIAGIAMGFDDNLI
                     GRAADVTIKEQRQLIIVPRETPLSPIHLDNLAKLAHIGVQIIPPIPAFYQHPQTIQDLI
                     EHHTMKLLDALHIKTETASRWNGASLR"
     CDS             complement(10583..12058)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     gallic_acid_met: gallic_acid"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_243"
                     /sec_met_domain="gallic_acid (E-value: 1.9e-229, bitscore:
                     755.3, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTASPWDLRKVLDELKQDPQQYHETDVQVDPDAELAGVYRYIGAG
                     GTVERPTQEGPAMMFNNVVGFPTTRVLIGLMASRKRVGKMFHQDYHTLGRFLNKAVLNP
                     IQPVTVEESAAPAHEVVAKASDPDFDIRKLVAAPTNTPQDAGPYITCGVVLGSNMAKTM
                     TDVTIHRMVLEDKDTLGIYIMPGGRHIGHFAEEYEKANKPMPVTINIGLDPAITIGATF
                     EPPTTPLGYDELGVAGAIRQEPVQLVQAVTVDEKAIARSEFTLEGYIMPNTRIQEDINT
                     HTGKAMPEFPGYDGDANPALQVIKVTAVTHRRDHPIMQSVIGPSEEHVSMAGIPTEASI
                     LQLVDRAIPGKVKNVYNPPAGGGKLMTIMQIHKDNPADEGIQRQAALLAFSAFKELKTV
                     WLVDDDVDIFDMNDVVWTMNTRFQGDQDIMVLPGMRNHPLDPSERPQYDPKSIRVRGMS
                     SKTVIDGTVPFDMRDQFKRAAFKKVSDWQKYLK"
ORIGIN
        1 acaatctaca ccgccattca ggctcaaggc ggccgcatca tcaacgaaat cacggatgaa
       61 aatctggaac aactggccaa acggtttgac ttaacgccta acccagcctt tcttcacggt
      121 gattcactca tcagtcaggt aacgctaaaa gtgtaacgtt atctgctcat ggtaggatac
      181 ctcctaaaca cactctaaag agcccactga ttgttgaagg caattggtgg gcttttgggg
      241 ttgtggatga aagttggagg aaaggtgctt gttaaaagtg agcggatttt ctgactgcaa
      301 tttcagcgcg atacttaggg atggggaacc gcgggaacat catcttttaa cgataacaaa
      361 tagacgttag taagcccaag ttggttttac tagcgtctat tttgtttaca gctatcaggt
      421 atgaataaga cagcgagtta tttcagtcgg ccaaatgatg atgcgctttc ggataagtga
      481 gttgaatatg atgatcatca aacaaatttc cgtattctgg cgcgggttgc gtatcagtga
      541 taatctcact gatttgatcc atatttgtga tacgaatgta gtcactttga ttgaatttgg
      601 ttgaatcgat gccaagaatg acgcattttg cagcagctat catggcttct ttaacggctg
      661 cttgctctgg gtcagctaca tagataccgt cagcatcaat cgagcctatt gaaagcaggg
      721 caaagtcggg acgaaagctt tgaatttcgt ttatcgtcgt tgcgcccaaa gttgaagcag
      781 ttcttggagc cattttgcca ccaagaataa tcgtttcgac attgtttaat gaattaaatt
      841 gcatccccat gtttacgtta ttggtaatga cgtgcaagcc gacttgttcg tgtagaagct
      901 cgggcagact gaaaaaggtg gaactaccat cgataaagaa agctgcattg ctgggaatct
      961 tcgcggcaat ttggcgacta atgacgcgtt taagacgtgc gttttcgtta cgtctttttt
     1021 catacgtaaa ttccagattg tttccttgca gtaactgcac cgtaccatag tgccgccgga
     1081 tgatattgct gttttcaagc tcgataaggt cacgtctcag agtggactta ctggtgaaca
     1141 ttcgcttgct tagttgcgca atactgatct ctggtgtttc gcgtagaatc tgaatgattt
     1201 cattcagacg ctcgaatttt gctggacttt gtgacattac aaacgctccc tcaattgaat
     1261 tttattgaac cgatttgaac aggatgagcg gcattttgtg aacacttctc aaccttgatg
     1321 aaaccttaca aatactatag acacgcacat gaaagcgctt tagcattgaa agtgaaataa
     1381 gttaaaagat tcaaaaaggt tcaaaacttt tggtttaaat attcgattga ggtgagctag
     1441 ttatggatta tagcacaatg attcacaaac agctgatttt cttaaatgaa aatcagccag
     1501 accgtcagca tttatttcga gcggttgcag agaagcttca agctgccgga tatgtaaaga
     1561 aaacctacga ggcagctttg aatcgccgcg aagacgaatt tccaaccggc attgtctttc
     1621 ctgagatatc cgtcatgttg ccgcatgctg atcctgagca tgtcattaaa ccgtttatgg
     1681 cgattgtaaa gaacgctcag ccggttcggg tgctgcagat gggctacaac gagccggaag
     1741 atgcgactgc catgtttttc ttgggtatta cagattcgag tcagcaggta ggcctcttac
     1801 agattttcat ggatttacta caaaatcagg attttgtcgc caagtttaaa gcgacaaatg
     1861 accgtgatgc gatgtatcaa ctttttgtcg atacatttga agcacaaacc acaggaaaat
     1921 aattaaaaag gagcgtaaag atcatggcaa aaattgttgt tgcatgtgga tcaggcgttg
     1981 catcaagtga agcaactgcc agtcgaatta aggatttttt cgaaagtcac aatgttaaag
     2041 gcgtatcggt tgatgctact gattttaagc agttaccgga agttctgcat aattacgatg
     2101 tctatgtttg gattgcaaaa ccgaatcaac aattagagga actagccaag gaaaataata
     2161 tcgcggttgt aaatggtatg ccaattttta tgaatatgaa tcctgaaaag tcatataaac
     2221 aaattattca ggcattaaaa aacatgcagg ctgccggaaa gtagttgggt aaacggggac
     2281 gctagatgtg tcagcatatg gcggctcgtg ctcacttttt gaggaggtag aaaactgtga
     2341 cgatcttaaa agatgtcgtt aattatattt tgaatcttgg gggaccggtg tttgttccgt
     2401 taatcatgct gattctaggc ctggttgccg ggttgaagtt taaaaaatcg attgtggcag
     2461 cgttaacttt aggggttgcc ttttcgggga tgaccttggt tgttaactac atgatggatg
     2521 caatttcacc ggctgccaaa gctatgtcaa agttgttcca cctaagttta aacgcgattg
     2581 atgctggctg gaccggtgtt gcggctatca catggtcata taaatcggca tttctgtttt
     2641 tcccgttatt attagcgatt aactttgtga tgttgacgtt taattggacg aaaacattaa
     2701 acgtggatat gtggaacgtt tggaacaaga ttttcactta tgtcgtggtg ctttacttca
     2761 cgcataacgc tttctttgga ttcttggttg cagggattca gattgtgttt gagctcaagg
     2821 caggtgatat gtggcatcga catattgagg atctgacggg tatgcctggg gtaacagtgc
     2881 cacattttat tactttgttt gcggtgattc ttcaaccgtt aaataagtta cttgatttca
     2941 tcccgattat gaataaaccg tttgacgcgg atgccttaca aaaacgtatc ggtgtttggg
     3001 gtgacaacac agtgatgggt gcgttgatcg gggtactgtt aggatttggc gctggttatt
     3061 ccgtctccgg ttcattgaat ctggcaatca aagccgcgac tgccatgacg ttgttcccga
     3121 tgatttctaa actgtttatg acggcactgt caccgattgc cgatgcgatg agtggattta
     3181 tgcagaaaca cttcaagggt cgtgaagttt atatcggact tgattggcca atactcgctg
     3241 gccggaacga attatgggtg actgttatta tcttggttcc aatcatgctc gtcttcgcaa
     3301 tgattttgcc gcataatacg gttttgcctt ttgccggcat tattaaccta tcgtttgtga
     3361 atgctgcgct gttgctgaca ggggcaaact tattgcgaat gatcaccttg ggcattatca
     3421 caacaccgat tttcctctat ggtgcgactt attttgcgcc ggtcattacg aacctggcaa
     3481 agtcaaccgg aaccgtcaaa gttcaagcag ggcaacagct ttcgtggtca acttttgaag
     3541 gacccgattt ccgactcttc tttgctcaag catttaatgg caagtggtgg gcgattgctt
     3601 tagcagtttt atggacgttg ggattcattt ggctataccg tgatcagaat aaaatcaaat
     3661 taccaagtca acgttacggc accttgacga cacctgctct agcaacgaca agctcaacgt
     3721 cagcagcaga tagcgctgat gcagatatcg atttagacaa tcttagcggt ttagacttca
     3781 gcgatgcaaa ggcttcaaat gagagccagc agtcagatgc taaaaatgat gatgatttag
     3841 acgatcttgg cgggttggat tttagtcaga caagtcataa gaagaagggt gatcaaggtg
     3901 agtaagacct tagcatcttt tctggttttc attgatacca tcggcgtttc aattgcgttg
     3961 cttggcggta gtgtcgggct ttgcctcctg atgggcctcg ttaccatcgt attgtatagc
     4021 aaagttaatc ccgttttgtt cggtgattat gaccgcaagc gacgcgaacg aattaaccaa
     4081 cgtcgtaaag agttgttggc tcagcgtgta aaaaatggag gattttcaaa atgactgaac
     4141 agtatgtatt tgaaaatgag cgtaaggatt tggcagaagt agcgcgcgaa atgtttgtgc
     4201 gaaagaatac gaatgtcgct ggtggcaata tcagcgttcg tattaccgcg gataaagata
     4261 ttgattatgg cagcattcat attaaggccg gcaaagatta tcttattatg acgcctacca
     4321 tgatgtcaga agcttggtat gcgaagttac aaccaactca aattttggta gtcgatcttg
     4381 agactggcaa gcagattgat ggggtcggcc gtttgacccg ggaaattaat atgcatgaag
     4441 aggcttatcg cgccaatgat aagatccgtt gcgtttacca ttcacatgcc gaagaatcaa
     4501 tgttttgggc aactgctggc cttgatatgc caaatgttac cgaggtcact gaagaagtcg
     4561 gaccgattcg cgtattaccc tatgcaccgg cttgctcaaa agaacttgcc gacactgtct
     4621 ataatgggct caaagcggtg ggcgatgctg caaaggaaca cattttcttg ttaaatagcc
     4681 acggcgtttt gattacgtcg gaagatttgc atcatgcaac cgagattttg gagacggttg
     4741 agtggaatgc aaaaattgcc tatcagcaaa cggtcttcat gaagctgggg ctgctcgata
     4801 gttatcagtc ttgcggtaaa gcgagtgatg ggatgttgaa agaacaggta caggcctgaa
     4861 gctaacgatt tgttggcatg ccattcgctt acgataactg cttgtgctaa aagattgcaa
     4921 aagaactgag cagaacttaa aaaatcaaag tttcggtatg taagcgtttt gtcaaaaaac
     4981 tcttgttatg tggtaatccc catcatttat gccaacctaa aatgcccaca aacattgtgc
     5041 ttgtgggcat ttttcgttgc gttctttttg taaaagcgtt aaattttttg cttatttacc
     5101 tgtggtttca ccatgacgtc gccgcaaacc aaagaaaatc gcgacatcac caatgagggt
     5161 taatagcagc aagaaaccaa acgcatgttg ggaaccgatg gcagtgttgt gagcagaggt
     5221 tgaaccggct tgggccagcg ccatgatgag tgagacgacc gcagtaccaa gtgcaccggc
     5281 gaattgttgt agggtgttga agatggcatt gccgtcagtg gtttgttctt ggtgtaactg
     5341 agcttgtccg cttgtcataa tgttgcccat tgaaaagccg gtacctagca tgatgaaggc
     5401 atagccgatt aagacgatga ccggggctgc ggttaaggct tcaaggagta gccagataat
     5461 tccgataagc tgtaagcata gtccgataaa gatagggcgt ccaggaccta atttatcgta
     5521 caatttccca ctcatgggtg ccatgcatgc gcccagtgcc gctccaggta ataggagtag
     5581 gccggcagtt agtgaacttg tgtggttcac gagctgcaag tagttgggta agacaaaggc
     5641 aaacccgaca ttgacgattt gaatgatgag gaaggtcgtc atgtgcagat caaacggaag
     5701 atttttgaat aaccgtaaat taatcagtgg ttctttaaca tgcagtgagc gcatggtgta
     5761 ggcgccgagg cttaaaattg caatgacggc aaagatcaag gcgcggccgg gttggtgctc
     5821 aatgctatta agaccaagaa tcgcggtcgc aaagaaaatc gcaatgaata accaagccaa
     5881 aaagtcgaga tgaagatgaa ccgtttcaga gacttgctgg atggaaaata gtcccataat
     5941 caaagcggca atcatgacga atagcaggaa aataaagatc agatgccagt taatgtcaac
     6001 cagcacgcca ccataagtcg ggcctaaagc cggcgcaatg gcggttacca acgtcccgat
     6061 gcccatgaga aaaccaattt tttctaacgg tgcctgttcc aaaatgatgt taaacattaa
     6121 ggggagtgca atccccgtcc cgcagccttg gattagtcgt cccaccagca agattgcaaa
     6181 actgtttgca acgctgcaca gtgctaagcc gaggatgaag aaggcactgg cggtaagaaa
     6241 aagctgttta gtcgtgaagc gtcgttttaa gaacccggaa atcgggacga tgatggcaac
     6301 gatcaacaaa tagccggttg tcagccattg aatggttccc gtatcgacat taaactgccg
     6361 cattaaagtc ggaaaagtga cattcatggc agtttcaatg agtaccccgc aaaacgccat
     6421 cagaccagtg gcgagaatcg aaaggtataa tttaggtgtt acttttcttg tcataaaaac
     6481 ctccatcgtg tatagttcta tatcgaacta tagctactat agcggtctta ttttctgaaa
     6541 tcaaggctta attttaatgt aaacgctgac ctgagatttc attgaaactg aaaggggata
     6601 gacatcgtga cagtatcgct gggtattttg gttaaaaaat taaacaatga cctgcaacgt
     6661 tatgctgatc gtgaagctaa gcaactgggt ctaacacagg tacaaatgag catcatcgat
     6721 tttttggcac ggcaaggaac caaacggccg ttgtatcaga cggacgttga acatgaattc
     6781 aacatccaga aatcttcagc aacggcactg ttacaactga tggagcgcaa ggaattgatt
     6841 gttcgtgtgc cctccaagca agatgggcgg tataaagcga ttcagctaac ggaaaaatct
     6901 caaaaagtag cggcatatat tcggcatttc tttgaccaaa acgatgcttt tttgcgcaac
     6961 gctttgggag aagatgcgga agtagtcgtc aatgcgcttg agaaactgca aacaacgatg
     7021 gcggctaaat tagcagatca ttgagggaac atctttgaag tcaacaatta gcgtccatta
     7081 acgaattccc ggatctggtt gagcgattaa gcaggtgatt catcgggacc gtaatagtgt
     7141 ggtcttgacg ttgcaaatgt ttgatgtttt agccaagttg ttaacttagg cgctagttta
     7201 tggctgagat ctaatgcagc ctggatttgt actttgctga tgtgatcgat gtgcaatcct
     7261 gctaaaatgg tgcagcttcc gggcagtaat ggttgcagcg ctttggcact tggaagcgca
     7321 agtaaatcat ctttatgaaa tctgttatca tgactggggt agcggattgt ttgaatgggt
     7381 tgatctttgg ttaacgtgag aacatcgcca atatgcgggt ggtcgccgcc agtaatggta
     7441 atgagtaggt cacgtccgat cacagtaacg gtggcgatga gagtgacgtc agattgtgtc
     7501 acggttgtcg tataagtcgg gacagggtag tcggacattt tatagcttcc tttcggtggt
     7561 gaataagttg aattttgagg atttaaaaat atttgtagca ctgtatgagc ttaagagttt
     7621 ttccaaagca gcggtggttt tacatcttag tcaatcagcc ttgtctaagc gtattcagca
     7681 tattgaggct attctgggaa gtaagttggt ggatactagc aatcatcgcc gcatgcttgt
     7741 cacggaggct ggtgaacggt ttttctttca cgccagtaag atcttgcacc aagtcgagct
     7801 catgaacacg gatttaaata gtttgaagtc cttgagcaac ggtgttttaa cgatcggtgc
     7861 cgttccaatt cttggtcagt ttggcatcag tcgattaata aacgattttg ccgctcaatt
     7921 tccgaagctg gcacttcatg tggtcgaaca ggaaggcatt agcatcctca agcagctttt
     7981 gaccggtgat ttagatatgg cattgctacg tgatacacaa gcagaggtct tatcgacgcg
     8041 ggaatatgtc aaacttgatc tggctaaaga tgagttgcaa gttattctcg ctaagaccaa
     8101 tccattagca aaacgtccat cactgtctgc aaacaattta gccgccacaa cgattgtcag
     8161 cttgctaagc ggctctggtg tctttgagcc aatgcaggcg ttttttgcgg atcgtcatat
     8221 cgcacccaaa atcatcttta gcagtccgca tatcgagaca cttttgggga tggtcgaagg
     8281 cagccgccac gttacctttt tgttccgtca atcttaccag ccgtttgcca attcgaactt
     8341 tgttgctaag tcattgacgc cgaatatttg tagtcatttg caactggttt atcgccgcac
     8401 tagcaatccg gcaattctta aatttgctga ctacttgagc cagcaagtta ccgccgaaaa
     8461 aggttaatgg taaccgtgat tgcaaaatcc caagacgata tttcgactgt tgtgtagcag
     8521 tcaggatttt aacgatacag cagtagcccc taaagaaaaa tcatttagga gctacgttgc
     8581 attgatattg acttttaaca agggcaccgc tgttataaaa gtccagtcag ctggaaccaa
     8641 aagacttcta ccagcgcaac aataaacatg acggcagtta gcggaatgcc taacttcatg
     8701 acatcttttt gcgtatagcc accgccagtt tctggatcgg aaccgacaag gatagcaagg
     8761 ttatggaacg gcaagatgta gtgcaaatta accacagaaa agacgattaa tgaaattgcc
     8821 agcggattaa ccccaagtga cgaggttgcc gcgataatgg cagggattgt aatacccatg
     8881 acggcaataa ccgaacccat gaacatgtga atgatcatcg caaaaacggt aatgaccagt
     8941 gccagtaagt agagattatg tggtaaggct gaaggcagga tcgtttgggc aatccattta
     9001 ttcatgccgg taaaatcacc cacttggcca attgcaattg ccgaagtcag gaagaccaag
     9061 acattgacgg gaacacctga ccatgatttt gccgtcaaga cctcaccgat aaccggcaga
     9121 ctcatcagca aggcgacaat caaagttaac cagccaacgt caataccagt gatgccactg
     9181 gttaaccata aaccgatggc aatgacaagc cagacgatca ctcgaatttc tttatgcgtc
     9241 attgcccctt gatcggcctg cttggctttc agaacatcaa ggtcaatcgt gacttttttg
     9301 gttggtttga agaggaaaag aaagagcagc atcgtgatga tcgcggcaat gatcatcgga
     9361 acccccatgt aaataaaata ttggacaaag ttgacgcttt tgccagaatc ggcaattgct
     9421 aaggggttga gcgatgtatc cccggttaga aaagcaccgg aaagaggaca ggaagcggca
     9481 aaaacggcta gtccaagttt agctcgatcc tgttgtggca ttttggcgct ggttgccacc
     9541 acatccatca cggacatgat caagaaggca cggggccagg gatgcggaat cagtaaagca
     9601 aggatgaagg ttaaggcaaa gattgagacg ataataccgg tccaactgcg aacaaatttg
     9661 ataatgaaag cataggcaat acgttcacct aggcctgatt cgcggacagc accggcaatt
     9721 aaataagcgc ccatcactaa ccacataatt gacttggtcc acgatcccgc aaatacctgt
     9781 gtcggggttg caacattcgt caagatcagc aacatcagat aaataccgcc aatataagcc
     9841 ggctgtgcaa tctggaatgc ccaccaaaca acggtcatta aactcaaagt aagatccatt
     9901 tgtgcttttt cattgatgcc gcttaatggg gccaggtaaa caatgaggcc caccgcaatg
     9961 ccgatgagaa aaccgatgtt ctgtttattg agaacttttt tcatcttaac gacgctccat
    10021 tccagcgact agcggtttcg gttttaatat gcaaggcatc taataatttc atggtgtgat
    10081 gctcgattaa atcctggatg gtttggggat gctgatagaa agccggaata ggcggaatga
    10141 tttgaacgcc aatgtgggct agtttagcga ggttatccag atgaattgga ctaagcggtg
    10201 tttcccgcgg cacaataatc aattgccgct gttctttaat cgtgacatcg gctgctcgtc
    10261 caatgagatt atcatcaaag cccatcgcaa tgcccgcaat ggttttcata cttgccggga
    10321 caatgaccat tgcatcggtt aaaaaactgc cgcttgcaat ggttgcccct tggttttgaa
    10381 caggataaac ataatctgcc aaagcttcga gttcgctttg tttcatgtcg gtctcaagtg
    10441 acaggttttg ctttgcccag gcactcatca ccaaatgaac ttcgacatca ggcaggcgat
    10501 gtaaatgctg gagcaggtta acagcgtaaa tagttccgga tgccccggta atccctacga
    10561 taatacgttt caattcaatc acctatttca aatatttttg ccagtcggaa acttttttaa
    10621 aggctgctcg tttgaattga tcgcgcatat caaatgggac ggtaccatca atgacggttt
    10681 ttgaactcat tccgcgtacc cgaatagact tgggatcata ttgcggtcgt tctgatggat
    10741 caagcggatg gttgcgcatg ccaggtaata ccatgatgtc ctgatcacct tgaaaacgcg
    10801 tattcattgt ccagacaaca tcattcatgt caaaaatgtc gacatcatca tcgaccagcc
    10861 aaacagtttt tagttctttg aatgccgaaa aagcgagtaa tgcagcttga cgttgaatcc
    10921 cttcatcagc tggattatct ttgtgaattt gcatgatggt catgagtttg ccgccaccag
    10981 ctgggggatt gtacacattc ttgaccttgc cggggatggc acgatcaaca agttgcaaaa
    11041 tgctggcttc ggttggaata ccggccatgg agacatgttc ttcactaggt ccgatgacac
    11101 tttgcataat gggatggtcg cgccgatggg ttacagccgt cactttaatt acctgtaaag
    11161 ccggattggc atcaccgtca tagccgggaa attctggcat ggctttgccg gtatgggtat
    11221 tgatgtcttc ttggatacgc gtgttaggca tgatatagcc ttccagtgta aattctgaac
    11281 gggcaatggc tttttcatcg acggtcacag cctgaaccag ttgcacgggt tcttgacgaa
    11341 tggctccggc aactcctagt tcatcgtagc caagcggcgt ggtaggcggt tcaaaagtgg
    11401 caccaatggt aatggccgga tccaagccga tgttgatggt caccggcatc ggcttattgg
    11461 ctttttcata ttcttcagca aaatgaccaa tgtggcgacc accgggcatg atataaatac
    11521 caagcgtgtc cttatcttcc aaaaccatgc gatgaatcgt cacatcagtc attgttttgg
    11581 ccatattgga acccaaaact acgccgcatg tgatgtaagg gccggcatct tgtggcgtat
    11641 tagttggtgc tgcaacgagt tttctaatgt caaagtccgg gtcactggcc ttggcaacga
    11701 cttcatgcgc aggcgctgct gattcttcga ctgtaacggg ttgaatagga tttaaaaccg
    11761 ctttgttcaa gaatcgacca agcgtgtgat agtcttggtg aaacatcttg ccaacccgct
    11821 tgcgactggc cattaaaccg atcaaaaccc ttgtcgttgg gaagccgaca acattgttaa
    11881 acatcattgc cggaccttcc tgtgtcgggc gttcaaccgt tccaccggca ccgatgtaac
    11941 gataaacgcc agcaagctct gcatcgggat caacttgcac atctgtttca tgatattgct
    12001 gcggatcctg ttttagttca tctaatactt ttcttaagtc ccaaggtgat gctgtcatat
    12061 taatcactcc taaaggccgg aacagcgaac cagccgaatt gatttcaaaa tctaggctag
    12121 tctggcttgg aaaccttttc aattcgagtt ttgaatgctg ttatgcctga atggaataag
    12181 aaaagggcaa tgacatttct taaaagatgt ggttgttaat gacagtcgac ttgtaaatag
    12241 tcaatatatg taactcgagg ctggtcgaaa tgaatgagat gacaatagga aaaaactaaa
    12301 agctggcttg atatattttg gctctctccc ccaaaacaaa aaacccgcac agatagtcat
    12361 gcaggtttgc aaacagttat tgagatgtgc aatgacttac cgataatgct aagcgctcca
    12421 agaattaagc ctaaaacggt gagtcacgtt cagttcattt aaaaaacgcc tgaaatcatt
    12481 gagatagcag gcgttttgac gttttgtatg gcatcatgaa caagacaaga aagtgaatga
    12541 tggttggcaa atccaacgta ttgtgaggtg gtcgcctatg cgcgatgatc aaaatctata
    12601 cggaaggaag tgcctagttg tctgttgctg atgcgttgat gctgatgctg gtcttcggtg
    12661 atttcatatt atcgttgatt gcgctgatca tcaccattat gctgataata caagacaatc
    12721 aaaaagaccg tcgctaatct gaagtgcaac aaaaaagtta gacagtttga aatttagtta
    12781 cacagcggct tgattccggt attcaatcgg ggtcaggcca tttttattga gtgaaata
//
