LOCUS       c00021_JACCKI0..       17084 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JACCKI010000008.1 Lacticaseibacillus rhamnosus strain AMC0712
            NODE_8_length_109246_cov_30.7109, whole genome shotgun sequence.
ACCESSION   JACCKI010000008
VERSION     JACCKI010000008
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 04:45:26
            Original ID  :: JACCKI010000008.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 85749
            Orig. end    :: 102833
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17084
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[90749:97833]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..12084
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..17084
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..17084
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(723..2078)
                     /locus_tag="ctg21_83"
                     /transl_table=11
                     /translation="MKAKDNQADRGDQPLSEKHHMQIPWYDVIVSEERQADHATLEERA
                     SLVGRVGIMLLACGTGAWRVREAMNTVARALRMSCSADIGLISLSYTCFSNNHAYSEVL
                     SLPKSGVNTDKLDALERFVRHFDKEYATQTVRDIHHRLDQIQKMSGNYDPLRAGLAAAL
                     ACCAFVFLLGGGPIEMVCCFVGAGIGNWLREIMIRRNWTLLACIGVSVAVACLVYFIAF
                     RGLEMGLGIAARHEAGYIGAMLFVIPGFPFITSMLDISKQDMRSGMERLLYALMITIVA
                     SLVGWLVAMVVHLRPENFVDLGLSPVLLLIYRLIASFCGVFGFSVMFNSPRRMAIQAGL
                     IGAVANTLRLELVDLNTIPPAAAAFIGALVAGLIASAINRVDGYPRISLTVPSIVIMVP
                     GLYIYRAVYNIGLNNIGVGAEWMTRAALIIMFLPLGLFTARLIMDSRWRQSD"
     CDS             complement(2258..2611)
                     /locus_tag="ctg21_84"
                     /transl_table=11
                     /translation="MDYEEELETKGYIDCLLHELHEQPQLIRQTNIEEVVERTKEEIIR
                     DGFHGYELRRHVFRMILRIDFILTTESVRLSQEGRDAIDELRRIANGQKKEDPRRFLRI
                     RHFLAQRFQHHMQ"
     CDS             complement(2729..4108)
                     /locus_tag="ctg21_85"
                     /transl_table=11
                     /translation="MMDPKKLATTEYYQHRFRNFSTMIIMPSTILFLGLLLFLIFARRE
                     VTVLTAAEIEPVKAAVTVQATAANRIVSNRMKEGKRVKKGETLLVYHDVANPTQIKLLK
                     QQLATLKEQQQQLDVLKQSVTENKDLFSKADRFGYQQQVQDYLSQRRVLTLTAEAEQAT
                     QTVASEKNKEIDRLLSASIQTSQAKMAAISEAKAAIQANKPLASRHAYHYLYQQYESEI
                     KNTDAEAQANLKRQYLAQLQTQLDEEQTNLTSLEQQRAGQKQADVSAQKAGETQANLTA
                     LQSRLQQTAVAEQTKVQQQVQADEAKLATLNDETQNYHVKASASGVLHLETALAGNQYV
                     PSGSVLARILPDLTEQTVADIKLGVSPTEIMSIKRGQKVRLRIAENVPTPTILDGRVYA
                     IDVAPTRDPKVGNFFTVKARVKLSKSQRQSLYYGLAGQASVITGTKTYWDYFADKMFNH
                     R"
     CDS             complement(4121..5014)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 218.4; E-value:
                     3.1e-66)"
                     /gene_kind="transport"
                     /locus_tag="ctg21_86"
                     /transl_table=11
                     /translation="MLTFNALLSYFTNPLESIINLQPKLQMARVANNRLNEVYLVESEF
                     KEQRHLTERHLIEGPIRVRDVSFKYGFGQDVLKNINLEVPENAKYTIVGMSGSGKSTLA
                     KLLVGFYPVDADKGTITFNGIPVKDINLTTLRQYIEYVPQDPFIFSGTVLENLTLGSRS
                     DVSEQDLTQACLAAEIAADIANLPQQWQTKLSESGSILSGGQKQRLAIARALLSPAKVL
                     IFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGKIVEQGDH
                     ATLLAQDGYYARLVHE"
     CDS             complement(5001..6305)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 59.2; E-value: 5e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_87"
                     /sec_met_domain="TIGR01193 (E-value: 4.8e-183, bitscore:
                     603.0, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 7.5e-42, bitscore:
                     135.1, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKHTPKLGQITYYKRFYTAQVDERDCGVAALNMLLKYNGSDYSL
                     AHLRELAKTNQDGTTALGIVRAAEALAFETKPVQADMQLFDLEDVPYPFIAHVLKRGEL
                     LHYYVVFKATRTSILIGDPDPSVRMTWLSREVFEKEWSGVAIFIAPAPQYQPRKEDKGS
                     LFAFVPMLAKQKGIIANIILAAVLITVISIVGSYFLQSIIDTYIPNAMRTTMGMIASGL
                     LVAYLLQAVLTYGQNFLMAVLGQRLAIDVILGYVRHLYELPMSFFSTRRTGEIVSRFAD
                     ANKIIDALANTIMTLFLDVWIVLILGIVLGIQNGTLFLVSLIAVPCYLVIVFAFQRPFD
                     RLNQETMESNAILSSSIIEDLNGIETIKSLTGERVSYERVDREFLTYLKRSFSYTKADQ
                     LQQAIKGLLKLALNVVDWGKFGDCQSNEFGADADL"
     CDS             complement(6554..6688)
                     /locus_tag="ctg21_88"
                     /transl_table=11
                     /translation="MKKFKDEEMPMMTDLELSSFVGGMLRDEGFTFNKFKNWLTSIFG"
     CDS             6810..8177
                     /locus_tag="ctg21_89"
                     /transl_table=11
                     /translation="LAIFRKLTAYKQKGKDYSMIISTDLYYFLFHLPIFLIDLTFLSYI
                     YFNDFKLRHIFLWSLAAGTLSTFLSSVGEITFGILYATNISKKYQRFDIFWVFLFLELN
                     LIVINLQLLVTKIVFLFLSVQSSTISNSIKLIIDVIFAIVMSQVLMKKKLFINSIREQI
                     QKKIAIWRPAVIYLIVTCVSLYCLEFAFSFLEITDILTLLILLTLILFMVINVFSLFFI
                     VKSYQYSLELLVIKHAEASKRAYYSALEQQRINTSRILHDYKNLLATLQLSLQKSSPHH
                     SSDVRTIVTQAQDALQKAEIGKDALALIESDPLRSLLYLKWSESANRGITMYMHTKDTV
                     RSLESDVGFAIIRILGILIDNAIDETATLKLKSFRVLLLPARDHLEIVVANPIPDGFDL
                     TRLNQKGFTTKGSGHGQGMSIINDLIQQNPNISMRKAIINNDQLKITLFIGGKAHA"
     CDS             8170..8946
                     /locus_tag="ctg21_90"
                     /transl_table=11
                     /translation="MPKNKTILNIYILEDNPDYLTFIQETVQQYLLIEELPAKIRLATT
                     SATELLAAVDWSAINDSIFLLDIELGDSATSGVDVATAIRRKSYYVDILFITSHVDEAL
                     RILEHKIAPLDMINKNSPSKTEKKIRNNILYAIKRLKARQVASPRLFSYSINSSIFSLE
                     MDELIYIQTAPGVSGTLELHAENEITTFPGNLKELATKYTNLCRCHKSILINPAHVMRL
                     DITNRFVYMDNQDKLEVSIRRMGELRNILTGTRALS"
     CDS             complement(9066..9341)
                     /locus_tag="ctg21_91"
                     /transl_table=11
                     /translation="MKGSTVNLYYATWLIFLATLFVFKDRKFVKRMISAILDDGSLVFG
                     IRTVIWLALLGLFFVTNHTDWPSAVLILLIVSAVILIDWHKTFQEE"
     CDS             complement(9593..9775)
                     /locus_tag="ctg21_92"
                     /transl_table=11
                     /translation="MTVVIYSILLILAFFFTFVFVTAIGWQMIDLLRHRLHPRTSFWEK
                     YSQLTQLAISILPFS"
     CDS             complement(10794..11093)
                     /locus_tag="ctg21_93"
                     /transl_table=11
                     /translation="MKKLKWFSGGNERAEQAIQLIDELLRDFDDSSSHSDRLRTVLRNN
                     REALIYKQAAVPFILSRMNLEISNALLQNNILLTKQQSDKFEQLSSLANIRYGY"
     CDS             complement(11272..11430)
                     /locus_tag="ctg21_94"
                     /transl_table=11
                     /translation="MTKLNEAELSKISGGIGPLAIPVAAILGFLATDAWSHADELVAGV
                     KQGWERS"
     CDS             complement(11899..12084)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_95"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.6e-08,
                     bitscore: 27.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHLKTLNTADLASISGGDNGNLWTFIGKAIGSTARSWAEGAMFA
                     PAIGPAKEIVDKLNGN"
     CDS             complement(12144..12329)
                     /locus_tag="ctg21_96"
                     /transl_table=11
                     /translation="MTMRTGLALKEISGKMLELTSGGNVPLSNCSVDPPNERHPPAYES
                     AFKYKLPIVHPIKVAT"
     CDS             complement(12715..12900)
                     /locus_tag="ctg21_97"
                     /transl_table=11
                     /translation="MSTRLTKLVDYGLIIATIIFAIYTVTSAIGWTNHGSFVTPMLILM
                     TLLMLLSEREEKQKSA"
     CDS             complement(12950..13756)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_98"
                     /sec_met_domain="Abi (E-value: 1.4e-14, bitscore: 47.2,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERKRHLLLSPGFCVLYILLLVVLISQLLLIPAVYTLKLDFWAGN
                     ILFKAIILLVMIALNWLLLKQVIVLKVTLSRPRLKPVIIWGLLFILIAWFTVTNRTPID
                     VLQAAVIGTIAAVPEEYLFRGVMLGGLIRAFYVAHHRHAKYQLLFCIGLSSLVFSLAHL
                     SNLPAQGLVITIAQVIQAFGMGAIFAALYIRYGSLLMPILIHFLIDFVITLVSGPYPKE
                     APSDPNAITMTIVHAFLIAGIYLAIALRLFRRGQNNEKFLARLSHS"
     CDS             complement(14077..14316)
                     /locus_tag="ctg21_99"
                     /transl_table=11
                     /translation="LRLAKTPQTITVYEILTAIEGTAPLFKLHQEIDPAAFVNGERVTS
                     WLTASTNVLNRAEDAMVQVLKQTSIADLAEAAEA"
     CDS             complement(14343..14516)
                     /locus_tag="ctg21_100"
                     /transl_table=11
                     /translation="MAFSVAFSQALEITAYVNAKSQAQHEDYLSIQKISEMLNIPVPSI
                     KKFRPHLKKVVF"
     CDS             complement(14571..15998)
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 326.9; E-value:
                     2.7e-99)"
                     /gene_kind="transport"
                     /locus_tag="ctg21_101"
                     /transl_table=11
                     /translation="MSKEEDKELINDGLADDTVIEETDAAITQSQRMSATQIIILGLAL
                     IGAFLGVLDTSIVYTGTVKMAAQLHLNAGALSWVQVAYALTYAGLMLVGGKLGDIYGRK
                     PLFIASLAIFGVGSLAVGAATNALVMISFRAVQGVGAAILAPNCLALLTDTFQGKARQR
                     AIGYYASVIGAGAAVGLVIGGFFATFASWRVGFYMNGPIALIMVGIAARYLPSAKRQTG
                     KIDWIGTILSVLAMTSISYGLDGSPWPIPTLLISAVLWVAFIASQGRVAHPTMPLEIFT
                     DRERMASYVSSLLFSAAAIGFWFYTPQFMQGVLGLTPFMTALGMVPMAILLFIVAVKAR
                     TFVDRWRNSKVMIFGFVTVLLSLAELAVASRFANYWFLLLGTLGFAVGFALAFATLATS
                     GLARIRPEISGAASGVYNTARQFGGALGLAIFAASTSSLTKIADVFGQAMLIGVGMTIV
                     GLILVVTLIIPAEKAAK"
     CDS             complement(16171..16503)
                     /locus_tag="ctg21_102"
                     /transl_table=11
                     /translation="MNMVQRNQILFILTGLNLSLKQAASGGLMETEAQEVVDEALDILK
                     RPNVLKNRAADYALSRLYARFTRLIGLQGMKLSAEANQWWQAVKDFMENDIHGELSQVG
                     GPHFII"
ORIGIN
        1 ttcccgctgg ctaaacaaca caatgtcggc attctcgcgc gggtaccctt ggcaagcggc
       61 ctcctgaccg gaaagttcga tgaaaagacc caatttgccc ccacagatca gcgcgccaac
      121 aaccgccatg gcgaacactt cagcaaaggc gaaactttct ccggcgttga ctatttaacc
      181 ggcgtcaaag cagcccgcga actaaaagag cggttaggat ctgacaatct ggccgcaacg
      241 gcactacggt ttattctaat gtacgatgcc gtttcagcgg tcattcccgg tgccagcaac
      301 ccgacccaga tcgaacgtaa caccgacgca gccgaaatgc ctgccttaac ccctgatcag
      361 atggcagtcg ttaaagatgt ttacgagcgc atgatcaaga atccggttgg ttacgagtgg
      421 tagtcaacta ataatcagtg agcggttgtc aaatgaaccc cctcaccgat ttatctaagt
      481 gtaagctgac tgtacaagcc atctgagtgt gatgacgatc acgcttgcca agttggtttg
      541 atgcttgcgt taactcgttg ctgccggcag ctttcttctg caacagcgct gttgctacat
      601 aacaactaac gagttcacca aaaagcaccc acacttccag ttgacgattc aagtcataac
      661 catcacaaaa acccactccg atttgaagtg gggttatttg tgttgctaaa aagtcatatt
      721 aattaatcac tttgccgcca gcgagaatcc ataatcaagc gagcggtaaa caagcccagc
      781 ggtaaaaaca taatgataag tgcggcacgc gtcatccatt cggcaccgac gccaatatta
      841 ttcaatccaa tattgtaaac tgcccggtaa atatacaagc caggcaccat gatgacgatt
      901 gatggcactg ttagcgaaat ccgcggatag ccatcaacgc gattaatcgc cgatgcaatc
      961 agcccagcca ccagtgcgcc gataaatgcc gccgcagcag ggggaatcgt attgagatcc
     1021 accaattcaa gccgcaacgt attcgccact gccccaatca acccggcctg gattgccatt
     1081 cggcgggggc tgttaaacat caccgagaat ccgaagaccc cacaaaagct ggcaatgagg
     1141 cgataaatca aaagaaggac cggactcaag cctaagtcga caaagttttc cgggcgtaaa
     1201 tggacaacca tcgcgaccag ccaaccaacc agcgaagcca caatggtaat catcaacgca
     1261 tacagtagtc gttccattcc cgagcgcata tcctgcttcg aaatatccag catactggtg
     1321 ataaacggga agcccggaat cacaaacaac atggcgccga tataccccgc ttcatgccgc
     1381 gctgcaatgc ccagtcccat ttccaatccg cgaaaagcga taaaataaac caaacaggca
     1441 accgccacac tgacaccgat acaagccagc agtgtccagt tacgccgaat catgatttca
     1501 cgcagccaat taccgatccc tgcaccaaca aaacaacaaa ccatttcgat aggaccgccg
     1561 cctaacaaaa agacgaaagc gcaacacgcc aaggctgctg ccaatccggc gcgcaacgga
     1621 tcgtaattgc cagacatttt ttgaatttga tcaagtcgat ggtgaatatc ccggacggtt
     1681 tgagtcgcat actctttgtc aaaatgacgc acaaaacgtt ccaacgcatc caacttatca
     1741 gtattcacac cgctttttgg cagtgaaagc acctcagaat aggcatggtt attgctaaag
     1801 caggtatacg ataaggaaat taggccaata tctgctgaac atgacatccg caatgctcga
     1861 gcaacggtgt tcatcgcctc acgcacgcgc cacgccccgg taccacacgc cagcaacatg
     1921 atcccgactc ggccgacgag tgacgcgcgc tcttcaaggg tggcatgatc cgcttgccgc
     1981 tcttcgctga caatcacgtc ataccacgga atctgcatat gatgtttttc tgaaagcggt
     2041 tggtctcccc gatccgcttg gttatctttt gccttcataa ctcgtgctaa tccttcttct
     2101 tatagggatt gtcttttcca aaaaaattga aaataaacat tcactattct agcacaattc
     2161 ataacagggt gtatttttga ctttttgaaa ctaacggatt tgaccgcctt attcatgaca
     2221 agcacgcaca aactagcaat catttctcgg tctcaactta ttgcatatga tgttggaatc
     2281 gctgcgccag aaaatgccgg attcgcaaaa agcgacgggg atcttccttc ttctgtccat
     2341 tggcgatcct tcgtagctca tcaatcgcat ctcgtccttc ttgactcaac cgtacacttt
     2401 cagtcgtgag gataaaatca attcttagta tcatccgaaa aacatgccgt cgtaattcat
     2461 agccatggaa accatcgcgg ataatctctt ccttggttct ttccacaact tcttcaatat
     2521 tcgtttggcg gatgagctgc ggttgttcat gtaattcatg caacaggcag tcgatatagc
     2581 cttttgtttc taattcttcc tcgtaatcca tacgccgatc accgcctttc atttgattaa
     2641 cttgatccgt atcgtttttt atggtcattt tcttaaataa tgggcatcgc cttttcgcta
     2701 ctaaacgaca aaagcggtaa ataccgattt atcgatggtt aaacatctta tctgcaaagt
     2761 aatcccaata agtctttgtg ccggtgataa cagatgcttg gccggctaat ccataataaa
     2821 gggactgccg ctgcgattta gataatttca cccgcgcctt gaccgtaaag aagttaccaa
     2881 ctttcggatc gcgtgttggg gcgacgtcaa tcgcataaac ccggccatct aatatggtag
     2941 gggtcggcac attctcagca attcgcaggc gtactttctg cccacgcttg atgctcatga
     3001 tctctgtcgg cgaaacgcct aattttatgt cagcaaccgt ttgttccgtt aaatccggca
     3061 gaattcgtgc caacacgctt cctgaaggga cgtattgatt ccctgccaag gcagtttcta
     3121 aatgcaaaac gccactggca cttgctttga catgatagtt ttgagtttca tcattcaagg
     3181 tagctaactt agcctcgtct gcttggacct gttgctgaac cttcgtctgt tccgcaacgg
     3241 ctgtttgctg caaccgactt tgtaatgcgg ttagattagc ctgagtctct cccgcttttt
     3301 gagccgatac atctgcttgt ttttgaccgg cccgttgctg ctctaaagac gtcaaattgg
     3361 tttgttcctc atccaactgt gtctgtaatt gagcaaggta ctggcgttta aggttcgcct
     3421 gtgcctccgc gtcggtattt tttatctcac tttcatattg ttgataaagg tagtgatagg
     3481 cgtggcgact ggccaagggt ttgttcgcct gaatcgccgc ttttgcctcg gagatagcgg
     3541 ccatttttgc ttggctcgtt tggatactgg cgcttagtaa ccgatcaatc tctttgtttt
     3601 tttcactagc gacggtttgg gttgcctgct cagcctctgc tgtcagtgtc agcactcgcc
     3661 gttgactcag ataatcttgc acctgttgtt gatagccgaa tcggtctgcc tttgaaaaaa
     3721 gatctttgtt ttcggtaaca ctttgtttca aaacatccaa ttgctgctgt tgctctttta
     3781 gcgttgccag ttgctgcttg agtaatttga tttgtgttgg attggcgaca tcgtggtaaa
     3841 caagtaaggt ctcgcctttc ttcacgcgct tgccttcttt catgcggttc gagacgatcc
     3901 gattggcggc cgtcgcctga actgtcacgg ctgcctttac cggttcaatt tcggcagctg
     3961 tcagcacagt tacctcgcgc cgagcaaaga tcagaaacaa tagcaagcct aagaaaagaa
     4021 tcgtactagg cataataatc atcgttgaaa aattgcgaaa gcggtgctgg taatattcgg
     4081 tcgttgcaag ttttttggga tccatcatct aaagctcacc tcactcatga accaggcgcg
     4141 cgtaataacc gtcttgggct aacaacgttg catggtcacc ttgttccaca attttgccat
     4201 gatccatcac cacaatttgt tcggttttag ccgcaatagt taagcgatgg gcaacaaaaa
     4261 taatggtccg atccgtcatt gccagcaagc gatcgacaat ttttcgctct gtaatggtat
     4321 ccagactgct ggtcgattcg tcaaaaatca gtacttttgc cggtgacaac aaggcccgtg
     4381 caatcgccag ccgctgcttc tgaccgcctg ataaaatgct gccgctttct gacaatttgg
     4441 tctgccactg ctgcggtaag tttgcgatgt ctgcggcaat ttccgcagcc aaacacgcct
     4501 gcgtcaaatc ttgttccgaa acatccgaac ggctacctaa cgtcaaattc tccaacaccg
     4561 tgcccgaaaa aataaacgga tcctgaggta catattcaat atattgccgt aatgttgtca
     4621 ggttaatgtc tttgaccgga atgccattaa acgtaatggt tcctttatcg gcatcaaccg
     4681 ggtaaaagcc aactaataat tttgctaatg tcgacttacc agaaccgctc ataccgacaa
     4741 tggtatattt agcattttcc ggcacttcaa ggttgatgtt ttttaacaca tcttggccaa
     4801 aaccatattt aaacgagaca tcccgaacgc gtatcggacc ttcgattaaa tgccgctccg
     4861 tcaagtgccg ctgttctttg aattccgatt cgaccagata aacttcattc aggcgattgt
     4921 tagcaacccg cgccatttgt aactttggct gtaggttgat gatgctttca agcggattcg
     4981 taaagtatga cagcagcgca ttaaaggtca gcatctgccc caaactcatt cgattggcaa
     5041 tcaccaaact tgccccaatc cacaacgttc aacgccagct tcaacaggcc tttaatcgct
     5101 tgctgtaact gatctgcctt ggtgtaacta aacgacctct tcaaataggt tagaaattcc
     5161 cgatcaaccc gttcatagct aactcgttcg ccggtcaagg acttgatggt ttcaatgcca
     5221 ttcaaatctt caataatcga tgaactcaag attgcgttac tttccatcgt ctcttggttc
     5281 aaccgatcaa acggccgctg aaatgcaaaa acaatcacca aataacacgg cacggcaatc
     5341 aatgacacta aaaacaaagt cccattttgg atccctagaa caatgcctaa tattaggaca
     5401 atccagacat ccaaaaacaa cgtcataatc gtattcgcca gcgcgtcaat aattttattg
     5461 gcatccgcaa accgcgacac aatctctccg gtccgccgag ttgaaaaaaa cgacatcggc
     5521 aattcatata agtggcgcac ataccctaaa atgacatcaa tcgcaagccg ctgccccaac
     5581 accgccatca aaaaattctg gccataagtc aacacagctt gcagcaagta agccaccaaa
     5641 aggccactag caatcatccc catcgtcgtc cgcatggcat tcggtatata cgtatcaata
     5701 atagactgca aaaaatacga cccaacgata ctaatgaccg taatcaatac cgcggccaga
     5761 ataatgttcg cgataatacc tttttgctta gccagcatgg gtacaaacgc aaacaaactg
     5821 cctttgtcct ccttacgcgg ctgatactgc ggcgccggtg caataaagat ggccacaccc
     5881 gaccattctt tttcaaacac ctctcgcgaa agccaggtca tgcgcactga cgggtcagga
     5941 tcgccaatca gaatactcgt gcgcgttgct ttaaaaacaa catagtaatg aagcaattca
     6001 ccgcgcttca gcacatgggc aataaacgga taaggcacat cctcaagatc aaacaactgc
     6061 atatccgcct gtaccggttt tgtctcaaac gctagtgctt cagcggcccg aacgattccc
     6121 aaagccgtcg tgccatcctg atttgtcttc gctaactcgc gcaggtgggc taacgaatag
     6181 tccgacccat tgtatttaag cagcatgttt aacgcagcca caccacagtc acgctcgtca
     6241 acttgtgcgg tgtagaagcg tttgtagtag gtgatctggc ctagtttggg ggtgtgttta
     6301 aacatgtaat tatctccact ttaaaaattg aattgccaat tgacatcagc ctctccagaa
     6361 caaaaaataa gtaaaagcac tatattgact aggtaaattg tgctatcatg cattttatcg
     6421 agggccatag cagttatatt aatataaaaa ttataaatat atgcaaattt aataattttt
     6481 atattgtgta gctcgcaata cgagattatt tgtaacctct tttacgagtg ttcttctccc
     6541 acacgtaaga aaactagcca aagatactcg ttagccagtt cttaaacttg ttaaacgtaa
     6601 aaccttcatc tcggagcatt ccgccaacaa aacttgaaag ttcaagatct gtcatcattg
     6661 gcatttcctc atctttaaat tttttcatta cctttttctc ccttcgtttt gtctttcgtt
     6721 caaagtgatc gtaccagatc tttaaaaatt ttggttaggc aaaaaataaa cgtagctttt
     6781 tcgccattta acgcagattt tcgagcacct tggcaatttt taggaagtta accgcctaca
     6841 aacagaaagg taaagattat agcatgatta tttctacaga cttgtattac ttcttgtttc
     6901 acttaccgat ctttttgatt gatcttactt tcctttcgta tatttacttt aacgacttca
     6961 aactcaggca tattttctta tggtcactcg ccgcaggaac gctctccaca tttctttcat
     7021 cagttggtga aataacattt ggtattttat atgcaacaaa tatttcaaaa aaatatcagc
     7081 gttttgatat cttctgggtt ttcttatttc tagaacttaa cttaattgtt attaaccttc
     7141 aattactagt cactaaaatc gtatttctgt ttctatctgt ccaatcatcc actatctcaa
     7201 atagcatcaa gctgatcatt gatgtcatat ttgcaattgt catgtctcag gtgttaatga
     7261 aaaagaagct attcattaat tctatccgtg aacaaatcca aaaaaaaata gctatttgga
     7321 gaccggcagt tatttattta atagtgacct gcgtttcgct ttactgttta gagtttgctt
     7381 tttcatttct tgaaatcacc gatatcctaa cacttcttat tttgttaacc ttaattcttt
     7441 ttatggttat caatgtattc tcgttattct tcatcgtaaa atcatatcag tattctttgg
     7501 agttgttagt tatcaagcac gcggaagctt caaaacgcgc gtactattca gcccttgagc
     7561 agcaacgtat caataccagt aggattcttc atgattacaa aaacttactt gcaacgttac
     7621 agcttagctt gcagaaatca tcaccacacc actcatcaga cgttcgaacg attgtcactc
     7681 aagcacagga tgcacttcaa aaagctgaga taggcaaaga tgccttagct ttgatcgaaa
     7741 gtgatccgct caggagtttg ctgtatctca aatggtccga atctgcaaac cgtggcataa
     7801 caatgtacat gcataccaaa gatacagtcc gatccctgga aagtgatgtc ggatttgcaa
     7861 ttatcagaat cttgggcatt ttaattgata atgctattga cgaaactgcc acacttaaac
     7921 ttaagtcttt cagagttctc ttattacccg cccgcgatca cttagaaatt gttgttgcaa
     7981 acccgattcc tgacggcttt gatttaactc gacttaacca aaaaggattt acaacaaagg
     8041 gctcaggcca cgggcaaggc atgtccatta tcaatgacct aatccaacaa aatcccaata
     8101 tcagcatgcg taaagcaatt atcaacaatg atcaattaaa gatcacgcta tttataggag
     8161 gaaaagccca tgcctaaaaa caaaacaatc ctaaacattt atattctcga agacaaccct
     8221 gactatctaa cctttatcca agaaactgtg cagcagtacc ttctgattga agaactaccc
     8281 gccaagatcc ggctggcaac aacgtcagca actgaactgc ttgcagctgt cgattggtca
     8341 gccatcaatg atagtatctt cctccttgat atcgagctgg gagattcagc gacaagcggc
     8401 gtagatgtag ccacagccat tcggagaaag tcatattatg tcgatatcct cttcatcacc
     8461 agccatgtag atgaagcttt aaggatttta gagcacaaaa tcgcaccgtt ggacatgatc
     8521 aacaagaact caccttcgaa gacagaaaag aaaattcgaa ataacattct ttatgcaata
     8581 aaacgtttaa aggcgcgtca ggtcgcatct cccagattgt ttagctacag catcaactcc
     8641 agcatttttt cacttgaaat ggatgagctc atctatattc aaactgctcc cggcgtctca
     8701 gggacactgg agcttcatgc agaaaatgaa attacaacct ttcctggcaa ccttaaggaa
     8761 ctggcaacca aatataccaa cttgtgtcga tgccataaga gtatcctgat taatcccgca
     8821 catgttatgc gtctggacat cacaaaccga ttcgtttata tggacaatca agataaactt
     8881 gaggtcagta ttcggagaat gggcgagttg cgcaacatct taacaggcac acgagcttta
     8941 tcttaagaag agtgtgactg ggcaatcatc ctagatttct gttaatcaac acagctgaac
     9001 gcacaaataa cgcatcctca atatcaagga tgcgttattt ggttggttta tacaggttgg
     9061 aaatactatt cctcctgaaa ggttttatgc caatcaatta aaattactgc actaacgatg
     9121 agcagtataa ggactgctga aggccaatca gtgtgatttg tgacaaagaa aagccctaaa
     9181 agagccaacc atatgacagt tctgatacca aatactaaac ttccatcatc taaaatcgcg
     9241 gaaatcattc ttttaacaaa tttgcgatct ttgaaaacaa acaaagttgc caaaaagata
     9301 agccatgttg cgtaataaag attcacagtg ctacccttca tcagctctac ttcaaccaac
     9361 gtgctatcga ctgacccgtt tgataaccag cgtcataaat cccctttaaa attcccggtg
     9421 aaaagtacca aaacgccatt attaaaaccc caatggcaac aagcaacgac actttctgtt
     9481 ggaatgataa tcttgcaaat tgatcgatta cgctcacctc gtttacgagc agacttattt
     9541 ttacttcttt cagtaatcca ttagtaacct gttctttatg ttctcccgcc ttctaagaaa
     9601 aaggcaatat actaatggcc aactgcgtca attgggaata tttctcccaa aaagatgttc
     9661 gcggatgaag ccgatgtctt aagaggtcta tcatctgcca gccgatcgca gttacaaata
     9721 cgaatgtgaa gaaaaatgcc agaatcaaaa gtatagaata tatcacaact gtcataagca
     9781 aagctccttg agtcttcctt taaatttaca ttgaagcggc aaattagcga gcacaggttc
     9841 ggagatacta tacgttctgc taaggtcatc atacaagtaa gaagtcacaa aaatgaagcc
     9901 attttaccta tttaatattg tttccgaaag gccttttact gtcaggaaga aaaaacaatc
     9961 gtgggttttg aaagctcatc ttatttagca tcagttctgc catactcacg cgcaagatct
    10021 cctgatttgt atttttgttt caatacaaat caggagactt ttgcgttttt tggctgatcg
    10081 aacatagtgt aacaagattc tgacactaaa aacagttccc aaatatcagt agtgtcacct
    10141 aaaatctcat ttgccgtcat gaacagccga tattgcatta ttatagcctg gcagatggct
    10201 gtgtcacaat agttgctgtc tccttgagat gacaggcttc ccactgacaa taacactgcc
    10261 accttaccaa tactttgaaa tcaaacaaag aaaatttgtt atttagagcg tttacggtct
    10321 ttaacctttg aagatgtgac acttaattta gagaaaagaa tcaaaacaat gaagattgaa
    10381 agcatctcta tgaacgcccg gacgatgaaa aaatcaaaac ccaagcaatc gacaatcagc
    10441 ttgtttaaga catcactgag cgaaaacccg ccgaaacaga tacaaacgat aatccagaaa
    10501 gaagcttcat taagctatgt gcgcatagtt ttaagaatcg tcatcgtacc ttcgctttgc
    10561 tcatcactaa atcatttatc gaccgatcag ttttggctct gtctttttaa gttagaccgt
    10621 tatattcgaa actagtttgc ctacgtcgcc gttataaaat ggacaacctt ttaggcatca
    10681 tccattgaca acaggcccat accaaccagc atcgcaatcg gagtttgatc tgcaccaaat
    10741 gaatcagtga gcctaaccat aatcaagcgc actcaccgtt ttaggagtgg cctctagtac
    10801 ccatatctga tattcgccag cgaagaaagc tgctcgaatt tgtcagattg ttgcttggtt
    10861 aacaagatat tgttttgcaa cagggcatta gagatttcta gattcatgcg gcttaaaata
    10921 aatggaaccg ctgcttgctt gtaaattaag gcctctctat tgttccttag cactgtccgt
    10981 aagcgatcac tatgggaaga actgtcatcg aagtcgcgaa gcagttcatc gataagctgt
    11041 atcgcttgtt cagcccgttc attcccacca gaaaaccatt tcaatttctt catctttcac
    11101 tccaaaaaag ttgcgctagt gcaccttcac ttgtaacacg tttggcgccg tgcattgcca
    11161 gatctgccgt agcaatgaca gaaagaacat gctcgcccac agataaaagg cttgttctgg
    11221 gcagagatac ttttacaacg gcgacaacgc ttaagaatta acgcaccgtt attacgatcg
    11281 ttcccatcct tgcttgactc ccgccaccag ctcatcagca tggctccacg catctgttgc
    11341 caggaatcca agaatagcag cgacagggat tgcgagcggt ccgataccgc cggaaatctt
    11401 actcaattca gcttcattca acttagtcat taaaattacc tccttgtatt tgtaagaaac
    11461 tactcgccag ttgatccaaa agtctttgtt atggatattg tggcgataaa atgctcatct
    11521 accgcacaac tttttgcaaa tacaaccatg gagtcatcag cggcatgcct ggattaaagt
    11581 cacttgacct tcaccatcga aattctgcta cttggtttgt acggcagcat tacagcgtac
    11641 agcttaggca ttgaacggaa cactcaaagt ttaagcgtag gtaataaacc agatggcatt
    11701 caaaatataa gcacgtttaa aggctatctg atgctcactg tcgagatatt tatcattcca
    11761 aacgcgatag tgaccatctt ttttacagca cgtatatacc aaaacaccta atagatatac
    11821 caagataaac gtagctaaca ttaaaagatt tatcttattc atacgtttgc ccgttcgagt
    11881 gcctattcat cccggatact aattgccgtt aagtttgtca acaatctctt tggcaggacc
    11941 aatggctggc gcaaacatgg cgccttcagc ccaagaacgc gcggttgaac caatggcctt
    12001 cccgataaag gtccacagat taccattatc gccaccagaa atacttgcca aatcagccgt
    12061 gtttaaagtt tttaaatgat ccatgttctt cctccttttt cctttatgag cctttcaatc
    12121 tatctatcag cctaaattat cacttaagtc gccaccttaa ttggatgaac aatcggcagt
    12181 ttatacttaa atgccgattc gtaagctggc ggatggcgtt cgtttggtgg atccacactg
    12241 caattggata aaggaacatt cccaccgctc gtcaattcaa gcatttttcc cgagatttcc
    12301 ttcaaagcta gtcctgttcg catggtcatc ccattttcct cctttccctt tgttagaagg
    12361 acttcccttc ttccccatca atataaagta gacagccagg tttgtgggaa tgaatttttt
    12421 aacgtcgatt tttgcaagaa aatcgtcgta aaaaacctaa ttttgacgtt tatcgttaaa
    12481 aacccggcga ttatttgata ttgccgcctt ctcttcaaaa ctcaagcaac tgcaactgta
    12541 tttactttta cccatgtctt tttcgccact gtgagcatcc agtcttaagc caacttagaa
    12601 aggcgattag gctcgcggcc agcatgtgca tccattcgcc ggggaaatga tgacaaactg
    12661 cacacatata accgacaata aatgttaata agcagcgcca aaatcttttt tgattcacgc
    12721 gctcttctgc ttttcctccc gctcgcttaa cagcattaac aacgtcatca aaatcaacat
    12781 tggcgtcaca aaactcccat gattggtcca cccaattgcc gatgtgaccg tataaatggc
    12841 aaaaataatg gtagcgatta tcaacccata atcgactagt ttagtcagtc gcgtagacat
    12901 cgtttttctc cttaaactcg ttctatcata attgatacat acagccagtt tacgaatgcg
    12961 acaatcgtgc cagaaacttt tcattgtttt ggccacggcg aaaaagtcgc agtgcaatcg
    13021 ccaggtaaat cccggcaata aggaatgcgt gaacaatcgt catcgttata gcgttgggat
    13081 cactaggcgc ttctttcgga tacggtccac taaccaaagt gataacaaaa tcaatcaaaa
    13141 agtggatcaa tattggcata agcaacgatc cgtaacgaat ataaagtgct gcaaaaatag
    13201 cccccatgcc aaatgcctgg atcacttggg caattgttat cacaagccct tgagcaggca
    13261 aattactcag gtgagccaat gaaaaaacaa gactgcttaa ccctatgcaa aataagagtt
    13321 ggtatttggc atggcgatga tgggcaacat aaaacgcccg aatcaacccg ccaagcatga
    13381 cgccacgaaa caaatactct tcgggaacag cggcaatagt accaatcaca gctgcttgca
    13441 agacgtcaat cggtgttcga tttgtaaccg tgaaccaagc gataagtata aagagcagtc
    13501 cccaaatgat aactggcttc aatcgtggtc gactaagtgt cacttttaag acgataactt
    13561 gtttcagtaa cagccaatta agtgcgatca tcaccagtaa aatgatggct ttaaataaga
    13621 tattcccagc ccagaagtcc aatttcagcg tgtaaactgc tggaattaaa agcagctggc
    13681 tgattagcac aaccaaaagc aagatatata aaacgcaaaa tcctggcgac aatagcaaat
    13741 gacgttttct ttccatttat ccaccttcac tcgcacgttt caatgcaacg cagcttcgat
    13801 atcgctaccc acaatatacc gaggctgcgc atgttacgga tcattaactt ttaaacgtcg
    13861 ggttttcgcc gataatcgtt gtattttgaa acttgacaac gcgttaatcg tccccatttc
    13921 cgaaaaggtt tgccaatgga ggcgcacttg ctgactattt actgactgcc ccacagttgc
    13981 acgatcctga aaatgccgta agcaaaatcg cctcatccaa taccaacgcg ccaacgttag
    14041 tcttgaatga ggcgatgaaa agttagattt cgatttttac gcttctgcgg cttcagccaa
    14101 atcagcaatg ctcgtctgct ttagcacttg caccatagca tcttcggctc ggtttagaac
    14161 gttggtgctt gctgttaacc aactcgtgac gcgctcgccg ttgacaaacg cggccggatc
    14221 gatttcctga tgaagcttaa ataacggcgc cgtcccttca attgccgtta agatctcata
    14281 aactgtaatc gtttgtggcg ttttggctaa tcgcaaaccg ccattgagac cggttttcga
    14341 cgttaaaata ccactttttt taagtgtgga cgaaattttt taatgctagg aaccggaatg
    14401 tttagcattt cggaaatctt ttgaatcgat aaatagtctt catgttgtgc ttgggacttt
    14461 gcgttgacgt aggccgtgat ttcaagtgct tgcgaaaatg cgactgaaaa agccatcgaa
    14521 tatacctccc attaaacgat tgtgtatatt ctattatacc aatgataccg ttacttggcg
    14581 gctttttctg ccggaataat gagcgtgacg acaagtatca ggccaacaat ggtcatgccg
    14641 acgccaatca acattgcctg tccgaataca tccgcaatct tagttaagct gctagttgac
    14701 gccgcaaaga ttgccagtcc taaagcgccg ccaaattgtc gggcggtgtt gtagacgcct
    14761 gatgcagctc ccgaaatttc cggccgaatt ctagccaaac ctgaagtagc gagtgtggca
    14821 aatgccagcg cgaatcctac cgcaaatccg agtgtcccaa gtaacaaaaa ccagtaattg
    14881 gcaaaccgtg atgccactgc cagttcagcc aatgaaagta gcaccgtgac aaatccgaag
    14941 atcatgacct ttgaattacg ccaccgatca acgaaggtcc gggccttgac tgccacaatg
    15001 aagagtaaga tggccattgg caccatgcct aatgcagtca taaatggcgt taatcctaag
    15061 acgccttgca taaactgagg tgtgtagaac caaaagccga ttgcagcggc actaaacaac
    15121 agagaactga cataagaagc catccgttcc ctatccgtaa agatttccag tggcattgtc
    15181 gggtgggcaa cgcgaccttg actagcaatg aatgcaaccc aaagaactgc tgaaatcagc
    15241 aacgtgggga ttggccatgg actgccatct aacccatatg agattgaagt catcgctaat
    15301 actgacaaga tcgtaccaat ccagtcaatc tttccggttt ggcgttttgc actaggtaaa
    15361 tatcttgccg caataccaac catgattaat gcgatcggac cattcatgta gaaaccgacc
    15421 cgccatgacg caaacgttgc aaagaagccg ccaatgacta aaccaaccgc tgcaccggct
    15481 ccaatgacgg aagcatagta gccgattgcc cgctgtcgtg cttttccttg aaaggtgtct
    15541 gttaacaaag ccaaacagtt cggtgcaaga atggccgcgc ccacgccttg aacagcgcga
    15601 aagctaatca tgacaagcgc attggtagct gccccgactg ccagactgcc aactccgaaa
    15661 atagctaaac tcgcaatgaa taatggtttg cgtccgtaaa tatcgcctaa tttaccgcct
    15721 actagcatca gcccagcata agttagcgca taggccacct gcacccaaga caacgcgcca
    15781 gcattcaaat gcaattgtgc cgccatttta acggtacccg tgtaaacaat cgatgtgtca
    15841 agcacaccta gaaaagcccc aatcagtgcc agccctaaaa taatgatttg agtcgctgac
    15901 atgcgctgcg attgggtgat tgccgcatct gtttcctcaa tgacggtgtc gtcagccagg
    15961 ccatcattga ttaattcctt gtcttcttct ttgctcatat gagatgcccc tttctatggt
    16021 tcacttagta tattccgttt atactaatat ggcaaatctt ttttaagcaa aaaaaccacg
    16081 tgttccttaa ttctatggaa acacgcggct acaagcgaat tcttttcggg ccggttactg
    16141 gaatcagacc atggcttggg caacaactgt ctaaataata aagtgcggcc cgcctacctg
    16201 actcaattcg ccatgaatgt cattttccat aaagtctttt accgcctgcc accactgatt
    16261 ggcctccgct gaaagtttca ttccttgcaa gccgattaat cgcgtaaacc gtgcgtatag
    16321 tcgcgacaag gcgtaatctg cggctcgatt cttgagcaca ttaggccgct ttaaaatatc
    16381 taaggcctca tctacaactt cctgtgcttc tgtctccatc aggccaccac tagccgcttg
    16441 tttcagactc aggtttaatc cggtcaaaat aaacagaatc tgatttcgtt gcaccatatt
    16501 catgagtgat cctccatgtc tggtcgataa gtgtttgcat taagatagcg ttttcttgaa
    16561 ttgctaactg caatatacca aatttatcaa gcttcaggtc aaactttcga taaacgtagc
    16621 cttttcgccg attaacgtta ttgcggacat gaatcgcccg gtccaaagcg catagaaaaa
    16681 gccgtggcgc attaaccacg actaatcgga agcgcgtatt tcagcatagt cgtaaaaagg
    16741 ccgaaatgac acagttcatc agcatcgaac aagctcatat cccatgcggc taattaatgc
    16801 ccgccacccc agacaatcgg aatagcaatc agcccagcag ccagcgcctg atcgcgataa
    16861 cgcttggcat tgacttgatc tgctggcaca tccgccttga tcgcattgaa aacggcgatc
    16921 atctcggctg gaatcgtgtg atgaatgaga taatacttgg aaatatcatg cgatagctgg
    16981 gtcacgactg cgacataagc tgttttgtcc tctgcatctt ccagttgttt cgcgttggat
    17041 tcgattattt gctttaattt ggcatcagct ttcacggccg gact
//
