LOCUS       c00055_JACEIM0..       15655 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JACEIM010000005.1 Lacticaseibacillus paracasei strain s-16
            Scaffolds_5_101806, whole genome shotgun sequence.
ACCESSION   JACEIM010000005
VERSION     JACEIM010000005
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2022-06-21 00:42:07
            Original ID  :: JACEIM010000005.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 86151
            Orig. end    :: 101806
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15655
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[96151:99396]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13245
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15655
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15655
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             1127..1651
                     /locus_tag="ctg55_81"
                     /transl_table=11
                     /translation="MTTIAAVRKDGVTALAGDGQVTLGEKVIMKGNAQKVRRIYHDQVV
                     IGFAGGVADAFTLQDWFEKKLEHYAGNLRRSAVALAQDWRKDPTLQKLEAMMIVMDEHD
                     LLLVSGSGEVIDPDEDVVAIGSGGNFAQAAAIAMLRHAPDMTPADIAKEAVNIAGNIDI
                     FTNHNVIVESF"
     CDS             1695..3104
                     /locus_tag="ctg55_82"
                     /transl_table=11
                     /translation="MAEVQTPKQIVEKLDQYVIGQDDAKRAVAVALYNRYRRMQLSPKM
                     QEEINPKNLLMIGPTGVGKTEIARRLAKIVEAPFVKVEATKFTEVGYVGRDVESMVRDL
                     AETAVAMEEEKQFSKVRIRAEKEANKRLVKILVPAIRKEKNTNPMAEMMSMLQGMQNGK
                     MPAGDDADAGGEVTDDIRNKRLSVAEQLEKGLLEDHEITVAVNDEKKGGGMGDMYGQMG
                     IDLSDTIGALMPKKKVERTMTVKEAREIFIKEESDKLVNHADIYHDAIQSAENNGIIFI
                     DEIDKIAAGNKHNSGEVSREGVQRDILPIVEGSQINTKYGPINTDHILFIGSGAFAEAK
                     PSDLIAELQGRFPIRVELKDLTEKDFVRILTEPDNALIKQYIALIGADGVKITFTKEAV
                     DRIAEIATQVNHDTDNIGARRLATILEKLLEDVLYEGPDMAMGSVTVTQQYVDDKIGHI
                     AADSNMTRYIL"
     CDS             3140..4018
                     /locus_tag="ctg55_83"
                     /transl_table=11
                     /translation="MVTIANDFLTVKISRHCAELTSIKDNLTGRERLWQADPAVWGRHA
                     PVLFPIVGALADNQYHYAGKTYHMGQHGFARDRDFTVLSATPFKASFVLKDDDKTRAMY
                     PFAFRLIITFALENNNLHVTYHVDNPDKSEPLFFSIGGHPGFKVPMTPDTQFSDYYLNF
                     KPRKSLVQIPLVAGEGIDYTHRTLAATDANLALTHETFDHDALIFALLGKTTFNLVSDK
                     TKHGVSVTMTDTPYLGVWSPYPTTGDFVCIEPWWGIADTIGSTGDLTRKLGINRLEPGT
                     AFEKGYMISIF"
     CDS             complement(4100..4723)
                     /locus_tag="ctg55_84"
                     /transl_table=11
                     /translation="LILVLCFILAYFIGAIPFGVVIGKLFYHTDIRKGGSHNIGTTNAY
                     RMLGPVGGSIVLVLDILKGTLAASLPILFGIEHHWLVLIVGLAAVFGHTFSIYIRFRGG
                     KAVATSAGILLAYNPPFFVIAFAIWFSLILLTSMVSVASTLGMVLITAWSLVYHDWLLT
                     TVACGLLVVFLIKHRANFKRIKAGDENMVPFGLGQYLRQHRGRS"
     CDS             5286..7298
                     /locus_tag="ctg55_85"
                     /transl_table=11
                     /translation="MDKATQAYNDSSIQVLHGLEAVRKRPGMYIGSTDGRGLHHLVYEI
                     VDNSVDEALAGFGDEINVTIHADNSVTVQDHGRGMPTGMHPSGKPTIEVILTVLHAGGK
                     FNQNSYKTSGGLHGVGSSVVNALSESLTVRVVRDKRAFEEHFINGGHPDGTLQKLGKVN
                     EPNGTTITFKPDPTIFQTTVFSYDTLAERLRESAFLLKNITINLTDERTGKHDSYHYPD
                     GLVSFVKYLNEGKDALSQVINFEGKKDGIVVDFAGQYNDGYSENLISFVNNVRTGDGGT
                     HEIGLRSGMTRAFNEFARKVGLLKERDKNLEGSDVREGFAGILSVRIPEEILQFEGQTK
                     GKLGTPQARTVVDGIVYDKLSTFLMENGEESQELVRKAVKARDAREAARKARDDSRTGR
                     KRKKDQGLLSGKLTPAQTKNPKRNELYLVEGDSAGGSAKQGRDRKFQAILPLRGKVLNT
                     QKAKLQDIVKNEEINTMIYTIGAGVGADFDMQQANYDKIIIMTDADTDGAHIQILLLTF
                     FYRYMRPLIDAGRIYIALPPLYRLQKGAGAKTKISYAWTDEELAKETKAMGKGYTLTRF
                     KGLGEMNADQLWETTMNPETRTLIRVRIDDAQLAERRVTTLMGDRVEPRREWIEHNVKF
                     DMDDDGSILETPTANHEKLQFGAKQIVKQLDKKGK"
     CDS             7305..9749
                     /locus_tag="ctg55_86"
                     /transl_table=11
                     /translation="LANQIQELTLEEVMGDRFGRYSKYIIQERALPDVRDGLKPVQRRI
                     LFAMNQDGNTYDKGFRKSAKSVGNVMGNYHPHGDSSIYEAMVRLSQDWKLRAPLIQMHG
                     NNGSMDGDPPAAMRYTEARLSKISKEMLADIDKETVDMVLNFDDTAQEPTVLPAGFPNL
                     LVNGATGISAGYATEIPPHNLREVINAVLYLLKHPTADLDTLMQYVKGPDFPTGGIIQG
                     LDGIKQAYETGRGKIVVRSRTHIETIRGGREKIVVTEIPYDVNKAQMIKKIDELRINKK
                     VDGIAEVRDESDRFGLSVVIELKKEADAHGILNYLFKNTDLQIAYNFNMVAIADMQPKL
                     LGLKAMLEAYVEHRRDVVTRRTRFDLNKAAARQHIVEGLIKMLSILDQVIAAIRASKDK
                     GDAKRNLVKKFDFSEAQAEAIVSLQLYRLTNTDITALQKEAAQLAKAIAEYQDILARPA
                     ARDRVIEGELKRIAKEYGDDRRSSIQAKIETLEVATTVTVADETVMVQVSRDGYVKRSS
                     LRSYQAVDPADNGLKANDLAIFTGELSTLQHLYIVTNAGNVIYRPVHEISDARWKDTGE
                     HLSQTVGLGSDEKVLAVFAFDQLDGAGSFVLGSSDGYIKQTALSDLQPQRTYKSKPMMA
                     MKLKDPAAIVTNAYFTTDQQQDVFVVSRHAYGLTFPLSDVSTVGARATGVKSMDLKPDD
                     EVVNFILVKDPTTAKVGILTQRGAFKKMALSEVGEMSRARRGLLVLRELKRDPHRIVAM
                     MSVDDATRLNVLTDTGKVTTLNPVQHPAGDRYSNGSFVIDTDVLGKPVFVQTKEEPADQ
                     VE"
     CDS             10001..12262
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_87"
                     /sec_met_domain="Gly_radical (E-value: 3.6e-41, bitscore:
                     132.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.3e-241, bitscore:
                     795.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQLDETKVPNYWEGFNGGDWQEEINVRDFIEHNLNQYDGDESFL
                     AGPTEATTVLNNQVLNLKKQERANGGVLDADNNIPSTITSHGPGYLNKDLEKIVGVQTD
                     KPFKRAFMPFGGIRMAEDALESYGFKTDPQEHKIFNEYRKTHNQGVFDAYTPDMRKARH
                     YKIVTGLPDAYGRGRIVSDFPRIAVYGIDRLMAEKFKDYNLTGDGEMTDDVIKLREEIN
                     EQYRALNDMKKMAKEYGYDISRPAANAQEAVQWIYFGYLAAVKTQNGAAMSVGRIDTVI
                     DAYIQRDMRLGKLNEEQAQELIDHLVMKLRMVRFIRTEEYNSLFSGDPIWATLSLAGMG
                     NDGRHHVTKTAFRFLKTLDNMGAAPEPNITLLWSERLPEGFKRYATEVSIQSSTIQYEN
                     DDLMRNEWGTDYYGIACCVSAQPIADGVQYFGARANLAKTVLYAINGGKDEIQEAQVGP
                     EYAPITSDYIDYKEFMNKFDKMMDWLADTYVNALNVIHYMNDKYYYEAAQLALKDTQLN
                     RTFATGISGLSHAVDSISAIKYGHVKAIRDENGVAVDFVADNDDYPRYGNNDDSADDIA
                     KWLVKTFYNKMNTHHLYRGAKLSTSVLTITSNVVYGKNTGTTPNGRQKGEPFSPGANPA
                     YGAEKNGALASLMSTAKIPYHYATDGISNTFGVTPNTLGHDDETRKDTLVHMVDGYMEN
                     SGMHLNINVFNKETLIDAQKHPEEYPTLTVRVSGYCVYFADLTKEQQDDVIARTFFEEM
                     "
     CDS             12394..13245
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 65.2;
                     E-value: 2.4e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_88"
                     /sec_met_domain="Radical_SAM (E-value: 2.3e-25, bitscore:
                     82.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLIDQSQSPLNILEQVGQDHDGPIKGYVHSVESFGSVDGPGIRF
                     VVFMQGCRMRCQYCHNPDTWNIGVGEEMTADQILADAQRYKAFWGDQGGITCSGGESLV
                     QIDFILELFTKAKALGISTCLDTSGGPFTRDQPWFGQFEKLMAVTDISLVDIKHIDSAE
                     HKKLTGFPNENILDMVQYMSAHGDDMWIRHVLVPERTDFDPYLKRLGDYIATLDKNVVQ
                     KVEILPYHTLGVKKYHELGITYPLEGIEPPSADRVKNAENLLHVKDYTGWQSWRPKPVA
                     SN"
     CDS             13370..14338
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     60.8; E-value: 3.2e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg55_89"
                     /sec_met_domain="LysR_substrate (E-value: 1.4e-26,
                     bitscore: 85.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 4.6e-19, bitscore: 60.8,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTKQERIFSSKTLTYFLQLAETMNYTQAAQLLGITQPALTQQIK
                     KLERTVGAPLFYSVGKKLHLSDAGQTMLKSTHEIYEILNQTTDEIQQTTSATVGKINIG
                     LLSSIEDSAFIAFIAHYYQLNPEVEVTLRMMTRHEIWESLENNQIDLAIMNLPDETIKN
                     WKPYASKKIIDEQLLFLHHDDALANRKRIHFKDTLAEPWATYPDDYFLGQLLREAYKNQ
                     MVDFPHVVAHFTTPYQLTQFVNLSGVNTALPTSFVRARADQIKAYAIAFDPAIRFEISF
                     VYRKEKADIPRISNFFQTFDDYLKEKDYLSRVSENRVKLDK"
     CDS             14368..15300
                     /locus_tag="ctg55_90"
                     /transl_table=11
                     /translation="MTTLIFGHQNPDTDAITSAMSWAEFQKQAGNTDVEAVALGGPNDE
                     TKFVLDHFKVQAPRVIKTAANETDHVMLVDHNEFQQSVSDIEDVTIDSVVDHHRIANFH
                     TAAPLFYRAEPVGSTNTVIFEMFQEYGFKISPTLAGLMASGLISDTLLLKSPTATDKDK
                     KILPEMAKIAGIDLQSYGLAMLKAGTNLAAKSDMDIIEGDAKSFTMGGKSIRIGQVNTV
                     DLNDIYARQDELISAMTKEAQAKGYDDFLLIATDILDSNSTGFAVGADRDKIASAFNEQ
                     FDKDARLALPGVVSRKKQVVPPMQSTFEG"
ORIGIN
        1 tttcaggagt atcttgaagt tgaacggcag tattcaccgg aaacagtgac ggcttatttg
       61 agtgatcttc gagaatttca ggcgtttctc aaggccaacg gcgggtttac tgactttcgg
      121 catgtggatg atttagacgt tcaaacttat ttgactgatc ttaacaaaca ggatttggca
      181 cggacatcga ttgcccgaaa aatcagtagt ttgagaagct tttaccgtta tttgacacga
      241 attgatgtcg tcaaacgcaa cccatttgag ctggttgaat taaaaaagca gcatcatcat
      301 ttaccacaat ttttctatga agccgagatt caggaactgt tcaagacagt tgctggcaaa
      361 accccgctgg atcaacgtaa tcgcgctttg ttggaagttt tgtatggcac cggtattcga
      421 gtttccgagt gtgccaaact gacattgaat caggtcgatt tcaatacggc attactgttg
      481 attcatggta aaggcaacaa agataggtat gtgccctttg gacagtacgc tcagcaagca
      541 ctacgaactt atttaaaaga tggccgacaa gtcttgatgg ctaaaagtca ggcacagcat
      601 cgatatgtat ttgtgaacca gtatgggcgt ccgattacct cgcgtggcat tgaatatatt
      661 ttggatcagc tcatcaagca gacgacgctg acagctaaca ttcatcccca catgctgcgg
      721 catagttttg caacccatat gctggatcat ggtgctgacc tgcgaactgt tcaagagcta
      781 ctgggtcatg caagtttatc aaccacacaa atctacacgc atgtcaccat ggcacattta
      841 aaaaatgagt atatgaaata ttatccgaag cataattaag actaaagcat gatgcaaaag
      901 cagtctgagt tttttaagct aagaacattg gcgataacag attaatcgct actttagctg
      961 tttttatccg acgagatacg cagataacgc gctcgcagtc gcagaaacct gcacataatg
     1021 acctggaagc ctaaatagcc aaaattcagc catttaggct tgcagcccac ttatgctccg
     1081 gtttctaagc gcttctgctt gcgctcactt aaaaaggagc atgactatga caacaattgc
     1141 agcagtaaga aaagatggtg tgaccgcttt ggccggtgac ggtcaggtaa cccttggcga
     1201 aaaggtcatc atgaaaggca acgcgcagaa agttcgccgg atctatcatg atcaagtcgt
     1261 catcggattt gccggcgggg tagcagatgc tttcaccctg caagactggt ttgaaaagaa
     1321 gctggagcat tatgcgggca acttgcgacg ttccgcagtt gcgctggctc aagattggcg
     1381 caaggatccg accttgcaga aacttgaggc catgatgatc gtgatggatg agcatgacct
     1441 gttacttgta tccgggtctg gcgaagtgat agatccagat gaagacgtgg tagcgatcgg
     1501 ctctggcggc aactttgcgc aagccgcggc aatcgcgatg ctgcggcatg ccccggatat
     1561 gacaccagct gacattgcca aagaagcggt gaatatcgca ggaaatatcg atattttcac
     1621 aaaccacaat gttattgtcg aaagctttta gtttgtaacc gtcggcaatt acattgatct
     1681 acaggaggct tatgatggca gaagtacaaa ccccaaaaca gatcgttgaa aaactcgatc
     1741 aatatgtcat tggacaagat gatgcaaaac gggccgtcgc ggttgccttg tataaccgtt
     1801 atcggcgaat gcaattatcg ccaaaaatgc aagaagagat taacccgaaa aacttactga
     1861 tgatcggacc aaccggtgtc gggaaaaccg aaattgcacg acgactggcg aaaatagttg
     1921 aggcgccatt tgtgaaggtg gaagcgacta agtttacgga agttggctac gttggccgtg
     1981 acgtcgaatc catggtccga gatcttgccg aaactgccgt tgccatggaa gaagagaagc
     2041 aattttcaaa ggttcgcata cgtgccgaaa aagaagccaa taagcgtttg gttaaaattt
     2101 tagtgccggc cattcgtaag gaaaagaata ccaatccgat ggccgagatg atgagcatgt
     2161 tgcaagggat gcaaaatggc aaaatgccag ctggcgatga tgcagacgca ggcggcgaag
     2221 tgaccgatga tattcgcaat aagcgtttga gcgtggcaga gcaactggaa aaaggattac
     2281 ttgaagatca tgaaatcacc gttgctgtca atgatgagaa aaaaggcggt ggcatgggtg
     2341 acatgtacgg tcagatgggc attgatctaa gcgacaccat tggcgcttta atgcctaaga
     2401 aaaaggttga gcggaccatg accgtcaaag aagctcgcga aatcttcatc aaagaggaat
     2461 ctgacaaact ggtcaatcat gccgacatct atcacgacgc cattcaaagt gccgagaata
     2521 acgggatcat tttcatcgac gaaatcgata aaattgctgc aggaaacaag cataatagcg
     2581 gcgaagtttc gcgtgaaggt gtgcagcgag atattttacc gattgtagaa ggatcgcaga
     2641 ttaacactaa gtatggtcct atcaatacgg atcacatctt gttcattgga tcaggtgcgt
     2701 ttgccgaggc taagcctagt gatttgattg ctgaacttca agggcgtttt ccaattcggg
     2761 ttgaattgaa ggacttaacc gaaaaagact ttgtgcggat cttgaccgag ccagacaatg
     2821 ctttgatcaa gcagtatatc gccttgattg gtgcagatgg cgtgaagatt accttcacga
     2881 aggaagcggt tgatcgaatt gcagagattg cgactcaggt caaccacgac actgataata
     2941 ttggagcgcg gcgactggcg accattcttg aaaaactgct tgaagacgta ctttatgaag
     3001 gtccagatat ggcgatgggc agtgtgaccg tcacccagca atatgtggat gacaagattg
     3061 gccatattgc ggctgattca aacatgacgc ggtatatttt gtagttaaca ataatgttgt
     3121 aggtaaagga tgaggatgta tggtaacgat tgcaaatgac tttttgacag ttaaaatcag
     3181 tcggcattgt gctgaactga ccagtatcaa agataacctg acaggcaggg agcgtctgtg
     3241 gcaagcagat cctgcggtgt ggggtcgcca cgccccggtc ttgttcccga ttgttggggc
     3301 gctggctgac aatcaatatc attacgcagg caagacttac cacatgggcc agcacggttt
     3361 tgcccgtgat cgtgatttca cggtgctctc tgcgacaccg tttaaagcga gcttcgttct
     3421 gaaggatgat gacaaaacgc gggcgatgta cccgttcgct tttcgtttaa tcatcacgtt
     3481 tgcactagaa aataacaatc tacatgtcac gtatcacgtt gacaatccgg acaaaagtga
     3541 gccactgttc tttagcatcg gcggccatcc gggcttcaag gtcccaatga cgccggatac
     3601 tcaattctcc gattattatt tgaacttcaa accgcgtaag tcgcttgttc agattccatt
     3661 ggttgctggt gaaggcattg attacacgca ccggaccttg gctgcaactg atgccaattt
     3721 ggccttaacg cacgaaacat ttgatcatga tgctttaatt ttcgcgttgc ttggtaagac
     3781 aaccttcaac ttggtttctg acaagacgaa acatggtgtc agcgttacca tgaccgatac
     3841 cccatatctg ggcgtttgga gtccgtatcc aaccactggc gactttgtct gcatcgaacc
     3901 ttggtggggc atcgccgaca cgattggcag cactggcgac ctgacgcgca aacttgggat
     3961 caatcgactt gaacctggca cggcatttga gaagggttac atgatcagca ttttctaagg
     4021 tgtcatcagt ttgtcgatta ggtacatgaa aaaaagacat ccagtttcgg atgtcttttt
     4081 ggttgccatc aaaaggtgac taggagcggc cccggtgttg acgaagatat tggcctaagc
     4141 caaagggcac catattttca tctccggcct tgatgcgttt gaagtttgcc cgatgtttga
     4201 tcaaaaagac aaccagcaac ccgcaggcaa cagttgtcag caaccaatca tggtaaacaa
     4261 gcgaccaagc tgtgatcaac accataccca gtgtgctggc aacgctgacc atggacgtta
     4321 gcaagatcaa actaaaccag atggcaaatg caataacaaa aaatggcgga ttatatgcaa
     4381 gtaaaatgcc agcgctagtt gccaccgcct taccgcctct aaagcgaatg tagatcgaaa
     4441 atgtatgacc gaatacggcc gctaaaccca cgatcagcac cagccaatga tgctcgatgc
     4501 caaagagaat gggtaagctg gcagccaacg tgccttttaa gatatccagc accaagacaa
     4561 ttgagccgcc gactggccct aacatgcgat aagcatttgt ggtgccaata ttgtgactcc
     4621 cgcctttgcg gatatccgtg tgataaaaga gtttaccaat gaccacacca aacgggatgg
     4681 cgcctatgaa atacgcgagt ataaaacaaa gcacaagtat caaatgtgcc cctcctctca
     4741 aactagaaac tattttagca tttttgactt ttgagtgata cgtcagtaga ataaaacgaa
     4801 cgtacattcg aataaaacct gtgaagcggg ttgtggcgcg atttggtggc gtcttgtgca
     4861 aggatcatgg cggggcacag cgtagatatg gtgccagcgg gcgatgaatt tcacgtcaag
     4921 aagtcatagt tatgtgccat gcttagggaa gtgcggtttt ctgctgagct ttgggccatt
     4981 gacacggcta ataaaattta aatgaacaat gatggtatta gccagctggg tcgattttga
     5041 ggagaaaaca ggagtcctga gagcaatacg gtgaggtctg ctgttgatgg tgttgatgcc
     5101 taaacgcact cgcagcaacc tgcgtgtaag gaccttgggt gcaatggtca aagtccaacc
     5161 atcgcaccca aggccgctta tgctccggtt tctaatcggg ctggctcgcg ctcttatttt
     5221 ttatttctga aatctcaacg cgtggtgtat tctataactt agttgttcaa aaaagggagt
     5281 ttactatgga taaagcaacg caagcatata atgattcatc cattcaggtg ctgcatggct
     5341 tggaagctgt gcggaagcgt ccggggatgt atattggttc caccgatggc cgcggtttgc
     5401 atcacttggt ctatgaaatc gtggacaact ctgtcgatga agcgctcgcg gggtttgggg
     5461 atgagatcaa tgtgacgatt cacgccgata actctgtgac cgtacaggat catggtcgcg
     5521 ggatgccaac ggggatgcat ccgagcggca aaccgacgat tgaagtcatt ttgaccgtgc
     5581 tacatgccgg cgggaaattt aaccaaaata gttacaaaac atctggtggc ttgcatgggg
     5641 ttggctcaag cgtcgtcaat gccttatcgg aatcattaac cgtgcgagtt gtgcgggata
     5701 agcgcgcatt tgaagaacat ttcatcaatg gcggtcatcc tgatggcacg ctgcagaagt
     5761 taggaaaagt caacgaaccg aatggcacga ccatcacgtt caagccggac ccgactattt
     5821 ttcaaaccac cgtcttcagt tatgatacct tggccgaacg cttgcgcgaa tcagcctttc
     5881 tactgaaaaa tatcacgatt aatctgactg atgaacgcac cggcaagcat gacagttatc
     5941 actaccctga tggcttggtc agttttgtta aataccttaa tgaaggcaaa gacgcattgt
     6001 cacaggtgat caattttgaa ggcaaaaagg acggtatcgt ggttgatttt gccggccaat
     6061 ataacgatgg ctattctgaa aacctgattt cgtttgttaa taacgttcgc actggtgatg
     6121 gcgggacgca tgaaattggc ttgcgcagcg gcatgacgcg agcattcaat gaatttgccc
     6181 gaaaagtcgg cttgctgaag gaacgcgaca agaaccttga aggcagtgat gtgcgtgaag
     6241 gttttgcagg tattttaagt gtccgcattc cagaagaaat tttgcaattt gagggccaga
     6301 caaagggcaa gcttggtacg ccgcaagccc gcactgtggt cgatgggatt gtctatgaca
     6361 agctgtcaac ttttttgatg gaaaacggtg aagagtcgca agagttggtt cgtaaagccg
     6421 tcaaagcccg tgatgcgcgg gaagcggctc gaaaagcacg cgatgatagc cggacgggac
     6481 gcaagcgcaa gaaggatcaa ggcttgcttt ccggtaaatt aaccccggcg caaaccaaga
     6541 accctaagcg taacgaattg tatctcgtcg aaggggattc tgccggtggt tcagctaaac
     6601 aaggccgaga ccggaagttt caggcgatct tgccattgcg agggaaagta ctgaatactc
     6661 agaaggccaa gttacaggac atcgttaaaa acgaagaaat caatacgatg atttacacca
     6721 tcggcgctgg tgtcggtgcg gattttgata tgcagcaggc caactacgac aaaatcatta
     6781 ttatgactga tgcggatact gatggcgcgc atattcagat tttgctacta accttctttt
     6841 atcgctacat gcggccgctg attgacgctg gccgaattta cattgctttg ccaccattgt
     6901 accggctgca aaaaggcgct ggtgctaaaa ccaagatcag ttatgcttgg accgatgaag
     6961 agttggccaa agagaccaaa gccatgggca agggttacac attgacccga tttaaaggac
     7021 tgggggaaat gaatgccgat cagctttggg aaacgactat gaatcctgag acgcggactt
     7081 tgatccgggt tcggattgac gatgctcagc tggcggaacg acgcgtgacc actttgatgg
     7141 gtgatcgcgt tgagccgcgt cgggaatgga ttgagcataa cgtcaagttt gatatggatg
     7201 acgacggcag tattttggaa accccgactg ctaatcacga aaaattacag tttggtgcca
     7261 agcaaatcgt caaacaactg gacaagaaag gaaagtaaaa gccattggcc aatcagattc
     7321 aagaactgac cttagaagag gtcatgggcg accggtttgg ccggtactcg aaatacatta
     7381 ttcaagaacg ggcgctgcct gatgtgcgtg acggcctcaa accggttcag cgtcgcattt
     7441 tatttgcgat gaaccaagat ggcaatacgt atgataaggg cttccgcaag tcggctaaaa
     7501 gtgtcgggaa tgtcatgggt aattatcatc cccacggcga cagctccatt tatgaagcga
     7561 tggttcggct aagccaggat tggaagttac gggccccact gattcagatg cacgggaata
     7621 acggttccat ggatggtgat ccgccagctg caatgcgcta tacggaagcg cgtttaagca
     7681 aaatcagcaa ggaaatgctg gccgatatcg ataaggaaac cgtcgatatg gtgttgaact
     7741 ttgatgacac ggcacaggaa ccaactgtgt tgcccgcagg atttccgaat ttgctggtga
     7801 atggtgcaac gggcatctct gcaggttacg cgaccgaaat tccgccgcat aacttgcgtg
     7861 aagtgatcaa tgcggtctta tacttgctga agcatcccac tgctgattta gatactttaa
     7921 tgcaatacgt caagggtccc gattttccaa caggtgggat tattcaaggg cttgatggta
     7981 tcaagcaagc ttacgaaacc ggtcgcggta aaatcgtggt tcgttctcgg acacacatcg
     8041 aaaccattcg tggcggtcgt gagaagatcg tggtcactga gattccgtat gatgtcaata
     8101 aagcgcagat gattaaaaaa atcgatgaat tacgcatcaa caaaaaagtg gacggtattg
     8161 ccgaagtccg tgacgaaagc gaccgttttg ggcttagcgt tgtcatcgaa ttaaaaaaag
     8221 aagccgatgc acatggcatc ttaaactatt tatttaaaaa taccgatctg caaattgcat
     8281 acaactttaa catggtcgct attgccgaca tgcagccgaa gttactagga ctcaaggcca
     8341 tgttggaagc atacgtcgaa catcgacgcg atgtggtcac tcggcgaacg cgttttgacc
     8401 tcaacaaggc cgctgctcga cagcacattg tcgaaggctt gatcaaaatg ctatcgattt
     8461 tggatcaggt catcgccgcg attcgtgctt ccaaggataa aggagatgct aagcgtaact
     8521 tagtcaagaa gtttgatttt tcggaagctc aggcggaagc gattgtttcc ttgcagctgt
     8581 atcgattgac caataccgat atcacggctt tacagaaaga agcagcacaa ttggcgaaag
     8641 caatcgccga gtatcaagat attttggccc gccccgctgc ccgcgatcgg gtgattgaag
     8701 gcgagttgaa gcggattgcc aaggagtacg gggatgatcg tcgcagcagc attcaagcca
     8761 aaattgaaac gcttgaagtg gcgacaacgg tgacggtggc tgatgaaacc gttatggtgc
     8821 aggtttctcg tgatgggtac gttaaacgca gttcactgcg cagttatcag gcggttgatc
     8881 cggccgacaa tggtttgaag gccaatgatc ttgccatttt cactggcgaa ctgagtacgt
     8941 tgcagcatct ttacatcgtg acaaatgccg gaaatgtcat ttatcgacca gtgcatgaaa
     9001 ttagtgatgc gcgttggaaa gacaccggcg aacacttaag tcaaacagtt ggccttggct
     9061 ctgacgaaaa agtcttggca gtgtttgctt ttgatcaact cgatggcgct ggcagttttg
     9121 tgttagggtc aagtgacggg tacatcaaac aaactgcctt aagtgatttg cagccgcaac
     9181 ggacgtacaa gagtaagccg atgatggcga tgaagctgaa agacccagcc gcgattgtca
     9241 ccaatgcata cttcacgact gatcagcaac aggatgtctt tgtggtcagc cgccacgctt
     9301 acggactgac attcccgtta agcgatgtgt caactgtcgg tgcccgggca accggcgtta
     9361 aaagtatgga tctaaagcca gacgatgagg ttgtcaattt cattctagtg aaggatccaa
     9421 ctacggctaa ggtcggtatt ttgacccaac gtggcgcctt caaaaagatg gccttaagcg
     9481 aggtcgggga aatgagtcgt gcccgtcgtg gtttactggt cttgcgtgag cttaagcgtg
     9541 atccgcatcg gattgtcgcg atgatgtcag tcgatgacgc tacccgcctg aatgttttga
     9601 ccgatacggg taaggtaacg acccttaatc cggtacaaca tccagcaggt gaccgctatt
     9661 cgaatggttc gtttgtcatt gacactgatg tccttggcaa gccagttttt gttcaaacca
     9721 aagaagaacc agcagatcaa gtcgaataaa tggtgatcat tgacgccact gtctgtacta
     9781 atacagatgg tggcattttt gattattata ggacagatca gttgtgcaca atttaacaaa
     9841 atgacgaaat catgggcgaa aagaagcgac gaagcacact taaaaaacaa tataacgcct
     9901 attatatggg caataaaacg cttgcataga tttggcggcg tgttatactg tgtttgtaag
     9961 aactgtcaca tctgtaatcc actttaggag gcaaacaact atgaaacagc ttgacgaaac
    10021 caaagttcct aattattggg aaggctttaa cggcggcgac tggcaagaag aaattaatgt
    10081 gcgcgatttt atcgagcata acctgaacca atatgacggg gacgaaagtt tccttgctgg
    10141 ccccactgaa gcgacaacag tcctgaacaa tcaggttcta aatttaaaga agcaagaacg
    10201 tgcaaatggc ggtgttttgg atgctgacaa caatattcct tctacgatca cctcacacgg
    10261 acctggttat ttgaacaaag atcttgaaaa gattgttggt gttcagaccg acaagccatt
    10321 caaacgagca ttcatgccat ttggcggtat tcgaatggct gaagatgcat tggaatctta
    10381 tggcttcaag acagatcctc aagaacacaa gattttcaat gaatatcgta agacccataa
    10441 ccaaggtgtc tttgatgctt atacccctga tatgcgaaag gctcgccatt acaagatcgt
    10501 gactggcttg ccagacgcat acggccgtgg ccggattgtt tctgatttcc cacggatcgc
    10561 tgtttacggg atcgatcgtt taatggctga gaagttcaag gattataact tgaccggcga
    10621 cggcgaaatg actgacgatg taatcaaact gcgtgaagaa atcaatgaac aatatcgtgc
    10681 cttaaacgac atgaagaaga tggccaagga atatggctat gacatctcgc gtccggcagc
    10741 taatgcgcaa gaagctgttc agtggatcta ctttggctat ctggctgctg ttaagacgca
    10801 aaacggtgcc gcaatgtccg ttggccggat cgatacggtt attgatgctt atatccaacg
    10861 cgatatgcgc ttaggcaaat tgaacgaaga acaggcacag gaactgattg atcatttggt
    10921 tatgaaattg cggatggttc gtttcatccg gactgaagaa tataactcac tgttctcagg
    10981 cgatccaatc tgggcaacct tgtcattggc aggaatgggc aatgatggcc gtcaccacgt
    11041 taccaagacg gctttccgtt tcctgaagac tttggacaac atgggcgcag caccagaacc
    11101 aaacatcacc ttgctttgga gcgaacgctt gccagaagga ttcaaacgct atgcaaccga
    11161 agtatccatc caaagttcaa ccattcaata tgaaaatgat gacctgatgc gcaacgaatg
    11221 gggtaccgat tactacggta ttgcttgctg tgtctcggca caaccaattg ctgatggcgt
    11281 tcaatacttt ggtgcccgtg ctaacttagc taagacagtt ctgtatgcga tcaacggtgg
    11341 gaaagatgaa attcaggaag cgcaagtagg gcctgaatat gcaccgatca ccagcgatta
    11401 cattgattac aaagaattca tgaataagtt cgacaagatg atggactggc tggccgacac
    11461 gtatgtcaat gctttgaatg tgattcacta tatgaatgac aagtattatt atgaagctgc
    11521 acagctggca ttgaaggata cccaactgaa ccggaccttc gcaaccggga tttccggcct
    11581 gtcacacgcg gttgattcca tcagtgcaat caagtatggt catgtcaagg caattcgcga
    11641 tgaaaacggt gttgcagttg acttcgttgc tgacaatgat gactatccac gttatggtaa
    11701 caacgatgat agcgctgatg acatcgctaa gtggttggtt aagaccttct ataacaagat
    11761 gaacacgcat catctgtatc gcggcgcgaa gttgagcacc agtgtcctga ccattacttc
    11821 caacgtggtt tatggtaaga atacagggac aacaccaaac ggtcgtcaaa aaggcgaacc
    11881 attctcacca ggtgccaacc cggcatatgg cgcagaaaag aacggcgcac tggcatccct
    11941 gatgtccacc gccaagattc cgtatcatta cgcaactgac ggcattagta atacgtttgg
    12001 ggttactccg aacacactgg gccacgatga tgaaactcgt aaggatacct tggttcacat
    12061 ggttgacggc tatatggaaa acagcggcat gcatttgaac atcaacgtct tcaacaagga
    12121 gaccctgatt gatgctcaga agcacccaga agaataccca acattgaccg ttcgggtttc
    12181 tggctactgc gtctacttcg cagatttgac caaggaacaa caagacgatg tcattgctcg
    12241 gaccttcttc gaagaaatgt aagcagctta actcaagaca ggaagccatt cctgttttgc
    12301 caaaagacgg caacgatgct gttgccgttt tttggcagaa tgaaatgaaa atcaattgaa
    12361 aacgacacat gatgttgtag tggaggcaat aagatgaaac tcatcgatca gtcacaaagc
    12421 ccattaaata tcttagaaca agttggtcag gatcatgatg gcccgatcaa agggtatgtt
    12481 cactcggtcg aaagttttgg ttcggtcgat ggccctggta ttcgcttcgt tgtctttatg
    12541 caagggtgtc gcatgcgttg ccagtattgt cacaaccctg acacctggaa cattggggtt
    12601 ggtgaagaaa tgacggccga tcaaattttg gcggatgccc agcgctataa agcattctgg
    12661 ggtgaccaag ggggtattac ctgcagtggc ggtgagagtt tggtacaaat cgatttcatt
    12721 ctcgaactct tcaccaaggc taaggcactg ggaatttcga cttgcctcga tacgtcaggc
    12781 ggccccttca cgcgtgacca accgtggttt ggccagtttg aaaagctgat ggctgttact
    12841 gacatctcat tagttgatat taaacacatt gattcggccg agcataaaaa gctcaccggt
    12901 tttcctaatg agaatatttt ggatatggtg cagtatatgt cggcgcatgg tgatgacatg
    12961 tggattcgcc acgttctggt cccggaacgc actgactttg acccttatct caaacggtta
    13021 ggggactata ttgcgacatt ggacaaaaac gtggtccaaa aagttgagat tcttccgtat
    13081 cacacgttag gcgttaaaaa gtatcacgag cttggcatta cgtacccgct tgaaggcatc
    13141 gaaccgccgt ctgccgatcg cgttaagaat gcagagaatc tgctgcacgt taaggattat
    13201 accggatggc aaagctggcg tccgaaacca gttgcgagca actgaatctt tagctagaac
    13261 ttaacgtaac gattaaaaac gcggcaaatt cgttgcgttt tttttcattg ccacttatga
    13321 tgatggttga acgatattat taaattataa acgaaaggga agccgcccta tgaaaacgaa
    13381 acaagagcgc attttttcct caaagacact aacttatttt ctgcaattgg cagaaaccat
    13441 gaactacacc caagccgccc aattgcttgg cattacccag ccagccttaa cacagcagat
    13501 caagaaattg gaacggacgg tgggggcacc gctgttttat tctgtcggga agaaactgca
    13561 tttatctgac gctggtcaga ccatgttaaa gtcaacccat gagatctacg agatcttgaa
    13621 ccagacaacc gacgaaattc aacaaacaac cagtgcaacc gtcggaaaaa tcaatattgg
    13681 gttattaagc tcaattgagg atagcgcctt tattgcgttc attgctcatt actatcaact
    13741 gaatcctgaa gttgaagtaa cgctacggat gatgacccgt cacgaaattt gggaatcctt
    13801 ggaaaacaac cagattgatt tggctatcat gaatctgcca gatgagacca ttaagaactg
    13861 gaaaccatac gccagcaaga aaattattga tgaacaattg ctgttcttgc accacgatga
    13921 cgccttggct aaccgtaagc gaatccattt caaagatact ttagctgaac cttgggcaac
    13981 ttatcctgac gactatttcc ttggacagct tctgcgtgag gcgtacaaga atcaaatggt
    14041 tgatttcccg cacgtggtcg cacatttcac cacgccatat cagttaaccc aattcgttaa
    14101 cttgtcaggg gtcaacacgg ccttaccaac cagttttgtt cgggcacgcg ctgatcaaat
    14161 caaggcctat gctattgcgt ttgatccggc cattcgcttt gagatttctt ttgtttatcg
    14221 caaagagaaa gctgacattc cgcggatctc gaacttcttc cagacctttg acgattatct
    14281 gaaggaaaaa gattacttgt cgcgggtcag tgaaaaccgt gttaaacttg ataagtaaac
    14341 tattcagttg aggagcgatc agataagatg acgactttga tttttgggca tcagaacccg
    14401 gacaccgacg cgattacgag tgccatgagc tgggcagaat ttcagaaaca ggcaggcaac
    14461 acggatgttg aggcggtagc attaggcgga ccgaacgatg aaactaagtt cgtccttgat
    14521 cactttaagg ttcaggcacc gcgggttatc aagacggcag ccaacgagac ggatcatgtc
    14581 atgttggttg atcacaacga atttcaacaa agtgtcagtg atatcgaaga cgtgacgatt
    14641 gattctgttg tcgaccatca tcgcatcgct aacttccaca cggcagcgcc gctgttttac
    14701 cgagcagaac cggttggcag caccaatacc gtcatttttg agatgttcca agaatatggc
    14761 ttcaagattt cgccaacatt ggctggtttg atggcttctg gtttgatttc agacacgctg
    14821 ttgttgaaat cgccgaccgc aaccgataag gataagaaga ttttgccaga aatggcgaag
    14881 attgccggaa ttgatttgca gtcatatggt cttgccatgc tgaaggcagg tactaatttg
    14941 gccgccaagt cagatatgga cattatcgaa ggcgatgcta agagtttcac catgggcggc
    15001 aagtctattc gcatcggaca ggtcaatacc gttgatctga acgacattta cgcacgtcag
    15061 gacgaattga tcagtgccat gaccaaagag gcgcaggcga aaggctacga cgatttcctg
    15121 ctgattgcca ctgacatctt ggacagcaat tcaactggtt tcgcagtcgg tgctgaccgc
    15181 gataaaatcg ccagtgcttt caacgaacag ttcgacaagg acgcgcgttt ggcattgcct
    15241 ggggttgttt cccgcaaaaa acaggtcgtt ccgccaatgc agagcacgtt tgaaggttaa
    15301 ctttcatctt taattgcaca caattgttct aaggaaagtc gcagctagcc agttgcggct
    15361 tttttgtttg caaaaagtct ctagccatct ttttgcgaaa tctgttaaat ataaagctga
    15421 ctagcagctc gtgatgcgtg aatttgaaat tcgtgtagta attcgcgggt cgaatcaaca
    15481 gcaagttgtc atgggtcatt ttggctggtt ttgaggcatg ctgagagacg cattctgaga
    15541 cgagttcggg aattcaactc cccagtttac aattcaagtg caacaccctg acgactagac
    15601 cataaaggcc atgaagacct attcttgtta gtgctagcta aacaagaaag cagga
//
