LOCUS       c00035_JACYOV0..       10245 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JACYOV020000040.1 Bacillus amyloliquefaciens strain LM LM_contig_40,
            whole genome shotgun sequence.
ACCESSION   JACYOV020000040
VERSION     JACYOV020000040
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 00:22:08
            Original ID  :: JACYOV020000040.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10245
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10245
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:3428](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(3..3428)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..10245
                     /SMILES="NC(C(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10245
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             complement(3..3428)
                     /NRPS_PKS="Domain: AMP-binding (248-645). E-value:
                     1.8e-107. Score: 351.2. Matches aSDomain:
                     nrpspksdomains_ctg35_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (752-821). E-value: 1.1e-25. Score:
                     81.5. Matches aSDomain: nrpspksdomains_ctg35_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (836-1119). E-value:
                     6.5e-94. Score: 306.0. Matches aSDomain:
                     nrpspksdomains_ctg35_1_Condensation_LCL.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     315.6; E-value: 8e-96)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_1"
                     /sec_met_domain="Condensation (E-value: 4.2e-79, bitscore:
                     254.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-118, bitscore:
                     385.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.3e-18, bitscore:
                     55.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKSIKGDKDSLGELKTEEHFLVASKPSKEKRMKNLTYKLSQQLS
                     DKLNVYCNGSDERLHIVLTAALTLLINQYTERQNIVIKTPVFKKNRTIDCEQEILTLKN
                     AVHGEDLLKEIIHKVEFTVEQALESPQNNSRTSDKMTGLPFDVMIVLENIQEYILNQEN
                     PAIHILFSFMNQRQYIETVIHYNERLYSQNMIKDLSLRFQMILEAMITPKNIRVKDMRF
                     LKEKNKQKKIFGWEDNYSKIGTISEVFEQQADEYSDKTALVLENSSMCYAELNHRANQL
                     ARYLQECGVKRGDLVGIALERSFDLYISILAILKSGGAYVPLDPQYPKQRLSFLIEDSG
                     VELLITNESIQSQLPPHGDGVICLDGMKEEIEKMDGSNIGIKGSLDDLAYVMYTSGSTG
                     LPKGVSIVNRGVIRLVKETDYAVFDENQTFLQLASAAFDASTFEIWGCLLNGGCLAIMP
                     PGIPTADDIAEAVKKYNITTLWLTAGLFSLVVDQQLESLKGLQQLLVGGDVVSVPHVQK
                     VLALGKVQVINGYGPTEGTTFTCCFPVPHDWKGSMLPIGRPISGTEIFILDSQLKPVAP
                     GIPGELFIGGDGLAREYWRRPDLTKERFISHPFNNDPSARLYKTGDLVRYLENGDVEFI
                     GRRDEQVKIRGFRIELGEIEARLINHTEIKEAAVTVNHNGDEDLYICAYYTSNHKIAKI
                     ELQHFLRDFLPEYMIPSYFKQMENMPLTVNGKIDRRALPRPDISQMSETKYEAPTNETE
                     KKLSEIWEAVLGRERVGIDENFFETGGHSLKASMLISRIRKTFGTDIKVKELFEQPTIK
                     QLSRLIQKRDKQNYPVISKARKQSYYQASSAQKRMFALWETDKDSIVYNLPIMIELNGK
                     LDVKKAESVLQEIIGRHEALRTSFDVVNGDVVQIIHDTWELEFDYQKLPSDGIRPYVNQ
                     FIRPFHLDKAPLIRGGLITYEDRNLLLLDVHHIAADGVSVGIIRKEFNALYAGHRLKQP
                     PLQYKDYSEWQVSSGTKEALKEQEEYWLKRLSGDLPILNLQTDYERPRVKSFEGSRISF
                     TADERLTSSLKSVAKETGTTLYMVLLAVYNVMLSKYSGQQDVIIGTAESGRSDTELENT
                     VGMFVNTVAIRNFPEEHKTFRAFLEEVKHHTLKDF"
     aSDomain        complement(72..920)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg35_1_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="6.50E-94"
                     /label="ctg35_1_Condensation_LCL.1"
                     /locus_tag="ctg35_1"
                     /protein_end="1119"
                     /protein_start="836"
                     /score="306.0"
                     /tool="antismash"
                     /translation="YYQASSAQKRMFALWETDKDSIVYNLPIMIELNGKLDVKKAESVL
                     QEIIGRHEALRTSFDVVNGDVVQIIHDTWELEFDYQKLPSDGIRPYVNQFIRPFHLDKA
                     PLIRGGLITYEDRNLLLLDVHHIAADGVSVGIIRKEFNALYAGHRLKQPPLQYKDYSEW
                     QVSSGTKEALKEQEEYWLKRLSGDLPILNLQTDYERPRVKSFEGSRISFTADERLTSSL
                     KSVAKETGTTLYMVLLAVYNVMLSKYSGQQDVIIGTAESGRSDTELENTVGMFVNTVAI
                     RN"
     aSModule        72..920
                     /domains="nrpspksdomains_ctg35_1_Condensation_LCL.1"
                     /incomplete
                     /locus_tags="ctg35_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(75..164)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_1_0008"
                     /evalue="1.90E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg35_1"
                     /protein_end="1118"
                     /protein_start="1088"
                     /score="39.5"
                     /tool="antismash"
                     /translation="DVIIGTAESGRSDTELENTVGMFVNTVAIR"
     CDS_motif       complement(429..455)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_1_0007"
                     /evalue="1.20E-03"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg35_1"
                     /protein_end="1000"
                     /protein_start="991"
                     /score="11.7"
                     /tool="antismash"
                     /translation="QYKDYSEWQ"
     CDS_motif       complement(486..551)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_1_0006"
                     /evalue="1.50E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg35_1"
                     /protein_end="981"
                     /protein_start="959"
                     /score="27.2"
                     /tool="antismash"
                     /translation="VHHIAADGVSVGIIRKEFNALY"
     CDS_motif       complement(744..854)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_1_0005"
                     /evalue="4.80E-12"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg35_1"
                     /protein_end="895"
                     /protein_start="858"
                     /score="38.3"
                     /tool="antismash"
                     /translation="VYNLPIMIELNGKLDVKKAESVLQEIIGRHEALRTSF"
     aSDomain        complement(966..1172)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg35_1_PCP.1"
                     /evalue="1.10E-25"
                     /label="ctg35_1_PCP.1"
                     /locus_tag="ctg35_1"
                     /protein_end="821"
                     /protein_start="752"
                     /score="81.5"
                     /tool="antismash"
                     /translation="EKKLSEIWEAVLGRERVGIDENFFETGGHSLKASMLISRIRKTFG
                     TDIKVKELFEQPTIKQLSRLIQKR"
     aSModule        966..2684
                     /complete
                     /domains="nrpspksdomains_ctg35_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg35_1_PCP.1"
                     /locus_tags="ctg35_1"
                     /monomer_pairings="val -> val"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(1464..1529)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_1_0004"
                     /evalue="5.50E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg35_1"
                     /protein_end="655"
                     /protein_start="633"
                     /score="37.6"
                     /tool="antismash"
                     /translation="FIGRRDEQVKIRGFRIELGEIE"
     aSDomain        complement(1494..2684)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg35_1_AMP-binding.1"
                     /evalue="1.80E-107"
                     /label="ctg35_1_AMP-binding.1"
                     /locus_tag="ctg35_1"
                     /protein_end="645"
                     /protein_start="248"
                     /score="351.2"
                     /specificity="consensus: val"
                     /tool="antismash"
                     /translation="FEQQADEYSDKTALVLENSSMCYAELNHRANQLARYLQECGVKRG
                     DLVGIALERSFDLYISILAILKSGGAYVPLDPQYPKQRLSFLIEDSGVELLITNESIQS
                     QLPPHGDGVICLDGMKEEIEKMDGSNIGIKGSLDDLAYVMYTSGSTGLPKGVSIVNRGV
                     IRLVKETDYAVFDENQTFLQLASAAFDASTFEIWGCLLNGGCLAIMPPGIPTADDIAEA
                     VKKYNITTLWLTAGLFSLVVDQQLESLKGLQQLLVGGDVVSVPHVQKVLALGKVQVING
                     YGPTEGTTFTCCFPVPHDWKGSMLPIGRPISGTEIFILDSQLKPVAPGIPGELFIGGDG
                     LAREYWRRPDLTKERFISHPFNNDPSARLYKTGDLVRYLENGDVEFIGRRDEQVKIR"
     CDS_motif       complement(1617..1703)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_1_0003"
                     /evalue="5.30E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg35_1"
                     /protein_end="604"
                     /protein_start="575"
                     /score="47.5"
                     /tool="antismash"
                     /translation="PGIPGELFIGGDGLAREYWRRPDLTKERF"
     CDS_motif       complement(2211..2264)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_1_0002"
                     /evalue="6.20E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg35_1"
                     /protein_end="406"
                     /protein_start="388"
                     /score="24.9"
                     /tool="antismash"
                     /translation="AYVMYTSGSTGLPKGVSI"
     CDS_motif       complement(2457..2498)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_1_0001"
                     /evalue="6.90E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg35_1"
                     /protein_end="324"
                     /protein_start="310"
                     /score="19.1"
                     /tool="antismash"
                     /translation="LAILKSGGAYVPLD"
     CDS             complement(3801..4496)
                     /NRPS_PKS="Domain: Thioesterase (2-227). E-value: 2.4e-38.
                     Score: 124.6. Matches aSDomain:
                     nrpspksdomains_ctg35_2_Thioesterase.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 223.2; E-value: 4.2e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_2"
                     /transl_table=11
                     /translation="MKKIFCLPYAGGSSAIYYKWRRLMSDSLTIHPIELKGRGTRINED
                     FYEHIDEAVNDIYDLIKDQIRECDYALFGHSMGGRLVYKLYSKIAEMQQKKPNHIFFSG
                     CGIPKTKKAEGMIHALPDSLFLQRIMDMGGTSEELLHNKELQQLYLPILRSDFKMLEED
                     VISENKTVMDCDITVLHGNNDKTISSDLICNWGHYTLGKCNFYTFEGNHFFIHQFSNEI
                     TDIINKTLR"
     aSDomain        complement(3816..4490)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg35_2_Thioesterase.1"
                     /evalue="2.40E-38"
                     /label="ctg35_2_Thioesterase.1"
                     /locus_tag="ctg35_2"
                     /protein_end="227"
                     /protein_start="2"
                     /score="124.6"
                     /tool="antismash"
                     /translation="KIFCLPYAGGSSAIYYKWRRLMSDSLTIHPIELKGRGTRINEDFY
                     EHIDEAVNDIYDLIKDQIRECDYALFGHSMGGRLVYKLYSKIAEMQQKKPNHIFFSGCG
                     IPKTKKAEGMIHALPDSLFLQRIMDMGGTSEELLHNKELQQLYLPILRSDFKMLEEDVI
                     SENKTVMDCDITVLHGNNDKTISSDLICNWGHYTLGKCNFYTFEGNHFFIHQFSNEITD
                     IIN"
     aSModule        3816..4490
                     /domains="nrpspksdomains_ctg35_2_Thioesterase.1"
                     /final_module
                     /incomplete
                     /locus_tags="ctg35_2"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       complement(4248..4289)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_2_0001"
                     /evalue="3.60E-04"
                     /label="NRPS-te1"
                     /locus_tag="ctg35_2"
                     /protein_end="83"
                     /protein_start="69"
                     /score="13.1"
                     /tool="antismash"
                     /translation="YALFGHSMGGRLVY"
     CDS             complement(4569..4742)
                     /locus_tag="ctg35_3"
                     /transl_table=11
                     /translation="MEELFGMAELIIGVLMNVFIGKIGQVAFGKDNRTTRIILRVIGIF
                     LIINGVSRAFHI"
     CDS             complement(4798..5964)
                     /locus_tag="ctg35_4"
                     /transl_table=11
                     /translation="VQLIAMIKHQLKLMLRNRLAIFATISVPLILTFLFSFSQDTDSKE
                     NLYIANADKSNYAAKLIEMIKEHKNIKVIKLTENELKKKVDDQDIPFGVVIEKGFGKDL
                     TDNHKIKMKIIQNYENGSGTLLEQLVTNEAGTLKKVVKDSQYMSAQLHTDSKDIEKNIF
                     KKLKNNSGIEVNDKTLSQGEHTQDNATVRLIGFLVMFIWFVVIQGLRTLIDEKENNTFS
                     RLLSTPINYTKYVLSKMAATYISGIIHIIVIILAGKYLLKISIGHNIFAIAVMLAVYLF
                     ALTCITMIMVPFMRSQKQFTSAASIIIAVSGMIGGSFFSLEIAPKYMQVISKFTPEAWA
                     IQSLNNIIFSKSTLGTEWLPIVIFASVGLLSIIVSFILISREIKKKKN"
     CDS             complement(5967..7175)
                     /locus_tag="ctg35_5"
                     /transl_table=11
                     /translation="LRKLFNLFFLDFKLLTKNKSFYLKLMLFPSLLILILGSVFSNSDS
                     KIEAFDVAFYSADSGESVSLGDVLKDKVFKKGDLKDIIHLKEAESYNDGEKLVKEGKAA
                     AFIYVPEHFTKAVMNNGKTNIDLIGDNNKTIDKNIVQAVLEGFTKSVKTMSAEQQEVIK
                     HISSGSSVPKEKIEKMMNDLADNDGISADIPKAATNKNAVPVDSMQYYSIAMVVMFSIM
                     TAFVLVHSIVDERQNNTLFRIKSTPTLNIQYVLGKLTGIIFAILMQMTAVILISWVVFR
                     MNWGNLFDIFVITVVYAFAIGSIVLFWGFTAKDHVAVSSMASPVLYIFSFLGGSFISKN
                     GLPDSLRVVQEIIPNGKAINSYLKVKQNIGLSGMYIDLLELIGIGLIFVFINIMVFNRK
                     KVA"
     CDS             complement(7191..8123)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 208.5; E-value:
                     1.8e-63)"
                     /gene_kind="transport"
                     /locus_tag="ctg35_6"
                     /transl_table=11
                     /translation="MLELKKLTKKYDDFTAVNNISLTVEDGEVFGLLGPNGAGKSTMVS
                     MISTVLAPTSGTIKVDNKSLKEKPIEIKKIMGVVPQDLALYETLSAKDNLNFFGSLYGL
                     KGKKLKERTDEVLEIIELTDKKNQNVSEFSGGMKRRVNIGVALMNNPKLLILDEPTVGI
                     DPQSRNHILETVKRLNKEKGMTVIYTSHYMEEVEYLCEKVAIVDHGSLIALGTKEELKE
                     NLNACDTLTVTFKGADEEALSRINSITGIDKVTVDHKQISMLVSTKERNIIEIVDDIKN
                     LGIDLTSFKYEEVNLESIFLQITGKNLRD"
     CDS             complement(8341..8994)
                     /gene_functions="regulatory (smcogs) SMCOG1016:LuxR family
                     DNA-binding response regulator (Score: 171.9; E-value:
                     1.8e-52)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg35_7"
                     /transl_table=11
                     /translation="MDIIIVDDQQIVREGLKMILSLHEEINIVGEASNGEHLLDLLKQI
                     RPEIILMDIRMPIMDGIEATKLVKERYPDIKVIILTTFNDSEYIFTGLKSGADGYILKD
                     SDSQEIIDSIKTACEGNILLNPKVTLKVVKALNSVEHNKELVQENNEKEQLVQLLTPRE
                     KEVAKQIMEGKSNKAISEALFITEGTVKNYVSRILEKLQMNNRTELSLYLQKHM"
     CDS             complement(9018..10175)
                     /gene_functions="regulatory (smcogs) SMCOG1048:sensor
                     histidine kinase (Score: 151; E-value: 8.5e-46)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg35_8"
                     /transl_table=11
                     /translation="MKNLSSISTRVLIEKTIICFSLYSIISSIFKTPTFTASESAYLLI
                     ITIFLVVNDHIRLKYLSGQYSFRYYASFLVSNLLSGILLFKINCLGSQIYNIFLLIEII
                     VTTRKLPWTVVSLHFIIFFTALKAAGTSGKDILMSYLVIMAIIYLFRNVLLEKAKIQTL
                     NKELQSVNTKLKNYSQKIQELTISKERTRIAQELHDSLGHYLIALTMNLEFADKIVSKN
                     PSEAKQVINKSHDLSKECIINLREAVALLNDPAPQKGLLKSINEIFENFQQTNEIKFEL
                     DMDNKVESADPDIKNCLYKTVQESITNGIKHGNATFFSIRIRKSFEKISISITDNGTGC
                     SEINKSNGIKGIEKRFAALGGEVDFHSGLDSGFTVEAVIPEIADL"
ORIGIN
        1 tcaaaatctt ttaacgtatg atgtttgacc tcttctaaaa acgctctgaa tgttttatgt
       61 tcctcaggaa aatttcttat ggcgacggta ttgacgaaca tccccactgt attctccagt
      121 tcggtgtctg accttccgga ctctgctgtt ccgatgatca catcctgctg accgctgtat
      181 tttgaaagca tgacattata taccgccagc agcaccatgt acaaagttgt tcctgtttct
      241 ttcgccaccg actttaagct tgatgttaac ctttcatcgg ccgtaaagct gattcggctt
      301 ccttcaaagc ttttgactct cggccgctca taatcagtct gcagattgag aatcggcaga
      361 tctccgctta accgcttaag ccagtactcc tcttgttcct ttaacgcctc ttttgttcct
      421 gagcttactt gccattctga ataatcttta tattgcagcg gcggctgttt tagtctatga
      481 cccgcataca gcgcattgaa ttctttgcgg attattccaa ccgatacacc gtccgcagcg
      541 atatgatgaa catccagcag cagcagattc cggtcttcat acgttatgag tccgcctctg
      601 attaacggtg ctttgtccaa atgaaagggt ctgataaact gattcacata tggtcgtatc
      661 ccatcagacg gcagcttctg ataatcaaat tcgagctccc atgtatcgtg aataatctga
      721 accacatcgc cgtttacaac atcgaaactt gtccgtaacg cttcgtgtct gccaataatc
      781 tcttgtaaaa ctgattcggc tttttttaca tctaattttc catttagttc gatcataatc
      841 ggcaagttat aaacgatact gtctttatcc gtctcccaaa gggcaaacat tcttttctga
      901 gcagatgatg cttgataata agactgcttc ctcgctttac tgatgaccgg ataattctgt
      961 ttatcccgct tttgaataag acggctcagc tgtttgatgg taggctgctc aaaaagctcc
     1021 ttcaccttta tatccgtgcc gaaagttttt ctgatgcggg aaattaacat agaagccttt
     1081 agtgaatgac cgccggtttc aaagaaattt tcatctatac cgacgcgttc cctgccaagt
     1141 acagcttccc aaatctccga aagttttttc tccgtttcat ttgtcggcgc ttcatatttt
     1201 gtttcggaca tttgagatat atcaggtcta ggaagtgccc gtctgtcaat tttcccattt
     1261 accgtcaaag gcatgttttc catttgttta aagtacgatg gaatcatata ttccggaaga
     1321 aagtctctca gaaagtgctg caattcaatc tttgcgattt tatgatttga agtgtaataa
     1381 gcacagatat ataaatcttc atcaccatta tgatttactg ttactgccgc ttctttaatt
     1441 tctgtatgat tgatcaatcg ggcttctatc tccccaagct cgattctaaa accgcggatt
     1501 ttgacttgct cgtcccgccg tccaataaac tccacatcgc cattttctaa ataacgcact
     1561 aagtctcctg ttttataaag acgtgctgaa ggatcattat tgaaagggtg tgatataaac
     1621 cgttccttcg ttaaatcagg ccgtcgccaa tactctcgcg ccagcccatc tccgccaata
     1681 aacagctcac caggaattcc cggcgctacc ggttttaatt gcgaatctaa aatgaatatt
     1741 tctgtaccag aaataggcct ccctatagga agcatactgc ctttccaatc atgagggacc
     1801 gggaaacaac aggtaaaggt cgttccctct gtcggcccat atccgttaat tacttgtacc
     1861 tttccaagcg ctaatacttt ttgaacatgc ggaacggaaa ccacatctcc gcctactaat
     1921 aattgctgaa gtccttttaa tgattctaac tgctgatcaa ctactagaga aaataaaccg
     1981 gccgtcagcc aaagagtcgt aatgttatat tttttcacag cttctgcaat atcatcagcc
     2041 gtcggtattc ccggaggcat tatagccaga catcccccat tcaataaaca gccccagatc
     2101 tcgaaggtag aagcgtcaaa agcagcagaa gctaattgca gaaacgtttg attctcatca
     2161 aataccgcat aatcagtctc cttcaccagc cgaatcacac cgcggttaac aatacttact
     2221 cctttaggca gtcccgttga gcctgacgta tacatgacat aagccaggtc atccaaggaa
     2281 ccttttatgc caatattaga tccatccatc ttttcaattt cttctttcat accatccaaa
     2341 cagattacgc cgtccccgtg aggcgggagt tgtgactgaa tgctttcgtt tgtaatcagc
     2401 aactctacac ctgaatcttc gattaagaat gatagtcttt gcttcggata ttgagggtct
     2461 aacggcacat aagcaccgcc tgactttaat attgccagaa tactaatata caaatcaaaa
     2521 gagcgttcta aagcaattcc gacaaggtct ccccgtttta ctccgcactc ctgaagatac
     2581 cgtgccagct ggttcgcacg gtgattaagt tctgcgtaac acattgaaga gttttctagt
     2641 accaaagcag tcttatccga atattcatca gcctgctgct caaacacctc cgaaattgtt
     2701 ccaattttcg aataattgtc ttcccagcca aagattttct tttgcttatt tttttctttc
     2761 aggaatctca tatctttcac tctgatattt ttaggagtta tcatagcttc aaggatcatc
     2821 tgaaatcgca gtgacaaatc ttttatcata ttttgagaat agaggcgttc gttatagtgt
     2881 atgactgtct ctatgtattg tctctggttc ataaacgaaa ataggatatg aatagcggga
     2941 ttttcttgat taagtatgta ttcttgaata ttttcaagga ctatcatgac atcaaaagga
     3001 aggccagtca ttttatcact tgttcgagaa ttattttggg ggctttccaa tgcctgttct
     3061 acggtgaatt cgactttatg tatgatctct tttaataggt cttcaccatg aacagcattt
     3121 ttaagagtca aaatttcttg ctcacaatca atcgttctgt tctttttgaa aacaggagtt
     3181 ttgattacaa tattttgtct ttctgtatat tgatttatta acaaagtcag tgccgctgtt
     3241 aatacgatat gcagacgttc atccgatcca ttgcagtata cattcagctt atcgcttaat
     3301 tgctgtgaca atttatatgt aagatttttc attctttttt ctttagaagg tttacttgcc
     3361 actaaaaaat gctcttcagt ttttaactca ccaagactgt ctttatctcc ctttatactt
     3421 tttgtcataa caaaaactcc ttcaattgat atcaaaattc aactcattca ctgaattaaa
     3481 acagcagagg ctttcggtgg atttttatgt taaactgcat cacaggcaat accgctcacc
     3541 aataattgtt gttgtagtct gacagtttat ttatcggcag caaaaaccat tttttaatga
     3601 tatagacccg tacaaacact ttttttaaaa taaggataat gaagaagaac tagccatctt
     3661 taagaaatat tatacaaata tttgagagtt gtcaattagc gggaaaaaac acctaagcac
     3721 attaacccag tttttatttt tcgtattaac ataaaaaaaa accgggacaa agtaacactc
     3781 ccgatttttt aatcaaaaat tcatctcaag gttttattta taatgtccgt tatttcattc
     3841 gaaaattgat gaataaaaaa gtgatttcct tcaaacgtat aaaaattgca tttccctaaa
     3901 gtataatgtc cccaattaca tattaaatct gagcttatcg tcttgtcatt attaccatgc
     3961 aacactgtta tatcacagtc cataacagtc ttattttcag aaataacatc ctcttccaac
     4021 attttgaaat cacttcttaa aataggaaga tataattgtt gtaattcctt gttatgtaac
     4081 agttcttccg aagtcccgcc catatccatg attctttgca aaaataaact atccggcaaa
     4141 gcatgaatca tcccctctgc tttcttcgtt ttaggaatgc cgcagccgga gaaaaatatg
     4201 tgatttggct tcttctgctg catttcagca attttactat ataacttata aactaatcgg
     4261 cctcccatac tgtggccgaa taaagcataa tcacactccc tgatttgatc ctttatcaga
     4321 tcatatatat cattaacagc ctcatctata tgttcataaa aatcttcgtt aattcttgta
     4381 cctcttcctt ttaactcaat aggatgtatt gttaaagagt cactcattaa ccttctccat
     4441 ttatagtata ttgcacttga tccccctgca tacggaagac aaaatatttt tttcataatt
     4501 cacctcagaa attttgtaat aacccgataa aaaaacaccc tgaaaaggat gttttttact
     4561 atctcatttt atatatgaaa tgctcttgaa actccgttga tgatgaggaa gattcctatt
     4621 actcttaaaa tgatccttgt tgttctgtta tcttttccaa aagcaacttg cccgatttta
     4681 ccgataaata cattcatgag tacacctata attaattcag ccattccaaa tagttcttcc
     4741 atacccaatt ccctcacgtc ctttttgatc tgttaatttt atcagattat tgttgattta
     4801 atttttcttt tttttaatct ccctgcttat taagatgaaa gatacaataa tacttaataa
     4861 gccgacactt gcaaaaatta cgatcggaag ccattcagtt cctaaggtac tcttactaaa
     4921 gataatgttg tttaaagact gtattgccca tgcttcgggt gtaaatttag aaataacctg
     4981 catatatttt ggagcaattt ccaatgagaa aaaggaaccg cctatcatcc cgcttactgc
     5041 aattatgatc gatgcggcag aagtaaactg cttttggctt ctcataaatg gaaccataat
     5101 catcgtaatg caggtcaatg caaataaata aacagcgagc ataacagcga tggcaaagat
     5161 gttatgacct atgctgatct tgagtaaata ttttcccgca agtataataa cgattatatg
     5221 aatgattccg gaaatataag tagcagccat tttggataaa acatattttg tatagtttat
     5281 aggcgtactt agtaatctgc tgaaagtatt attctctttt tcatcaataa gtgttcttaa
     5341 cccttgaata acaacaaacc aaataaacat tacaagaaaa ccaattaatc tcacggtcgc
     5401 attatcctga gtatgttcac cctgacttaa tgttttgtca ttcacttcta ttcctgaatt
     5461 gtttttcaat ttcttgaaaa tgttcttttc tatatctttt gagtccgtat gcaactgtgc
     5521 agacatatat tgcgaatctt taactacctt tttaagagtt cccgcctcat ttgtgaccag
     5581 ctgctctaac aatgttccgc tgccgttctc gtagttttgg atgattttca tttttatctt
     5641 gtgattgtcc gtcaaatcct ttccaaaacc tttttcaata acgaccccaa aaggaatatc
     5701 ctgatcatcg acttttttct ttaattcatt ttccgttagc tttataactt taatattttt
     5761 atgctctttt atcatttcaa tgagctttgc agcatagtta cttttatcag cattggctat
     5821 atacaagttc tctttgctat ccgtatcttg agaaaaagag aacaaaaatg taaggattaa
     5881 cggcaccgaa atcgttgcaa aaattgctaa tctatttcgg agcatcagtt tcagctgatg
     5941 tttaatcatg gcaatcaatt gcactactac gccaccttct tccggttgaa taccataata
     6001 ttaataaaga caaagatgag accaatacca attagctcaa gcaaatcaat atacatgccg
     6061 ctaagaccaa tattctgttt gacttttaaa taagagttta ttgccttacc gttcggtatg
     6121 atctcttgaa caaccctcaa gctatcaggc agtccgttct tagaaataaa actgcctccc
     6181 aaaaaactaa aaatataaag aaccggagaa gccatactgg acaccgccac gtggtcctta
     6241 gcggtaaaac cccaaaacaa tacaatgctg cctatagcaa atgcgtatac taccgtaata
     6301 acaaaaatat caaacaagtt gccccagttc attcggaata cgacccagct tatcagaata
     6361 acagcagtca tctgcattaa gatcgcaaaa ataatacctg tcaactttcc aagcacatac
     6421 tgaatattta aagtcggtgt agatttaatt ctgaacagcg tattattctg ccgctcatca
     6481 acaatgctgt gaacaagcac aaaagccgtc ataatggaaa acatgacaac cattgcaatt
     6541 gaataatact gcatggaatc gacaggaacc gcatttttat ttgtcgctgc ttttgggata
     6601 tcagcggaga tcccgtcatt atcggccaaa tcgttcatca ttttttctat tttttctttt
     6661 ggtacgctgc tgccggagct gatatgtttt attacttctt gttgctcagc gctcattgtt
     6721 ttcacgcttt tcgtaaagcc ctccaaaaca gcctgaacaa tatttttatc tatggtcttg
     6781 ttattatctc caattaaatc gatatttgtt ttcccgttgt tcataacggc tttcgtaaag
     6841 tgttccggta catagataaa agctgcagcc tttccttctt taactaattt ttcaccgtca
     6901 ttgtagctct cagcttcttt taaatgaatg atatctttga gatcgccttt cttaaaaact
     6961 ttatccttta agacatcacc taaagaaaca ctctcccctg aatctgctga gtaaaaagct
     7021 acatcaaatg cttcgatttt tgaatctgaa ttactgaaca cactgcccaa tatgaggatt
     7081 agcagtgatg gaaacagcat cagctttaaa taaaatgact tattttttgt taacagctta
     7141 aaatcaagaa aaaataagtt gaataatttt ctcaagatag cctcctccta ctaatctctt
     7201 aggtttttcc ctgtaatttg aaggaaaatg ctttccaaat ttacttcctc gtacttaaag
     7261 ctagtgaggt cgatccccag atttttgata tcatctacaa tttcaatgat gtttctttcc
     7321 ttcgtcgata caagcattga aatttgttta tgatctaccg tcactttatc aattcctgta
     7381 atgctgttta tccggctgag tgcctcttca tcagcaccct taaaagtaac ggttaaagtg
     7441 tcacaagcat ttaagttttc cttgagttct tctttcgttc ctaaagcaat aagagatcca
     7501 tgatcaacaa ttgccacctt ctcgcaaaga tactctactt cttccatgta gtggctggta
     7561 taaataacag tcattccttt ttctttattc agccttttta ctgtttcaag aatatgattt
     7621 cttgattgcg gatcaattcc tactgtaggc tcatcaagaa ttaataattt aggattattc
     7681 attaacgcca cacctatgtt gacccggcgt ttcattcccc cggaaaactc tgatacattt
     7741 tgattttttt tatctgtcag ttcaataatc tccagaacct catcagttct ttcttttagc
     7801 tttttccctt tcagcccgta aaggcttccg aagaagttca agttatcttt ggcgcttaac
     7861 gtttcatata aagctaaatc ctgtggaaca acccccatta ttttttttat ctcaataggt
     7921 ttttccttaa gtgatttatt atctacttta attgtcccgc tggtaggtgc aagaacagtg
     7981 ctaatcatag aaaccattgt tgatttgccg gcaccgttag gacccaatag tccgaatact
     8041 tctccatctt ctacagtcag cgaaatatta ttaactgccg taaagtcatc atattttttg
     8101 gtaagttttt ttaattcgag cataattaaa acacccctcg tggtatttcg gttcttttat
     8161 tttaacctga atggaatatt tttagaattt actatagtac tcatttacct tattacttta
     8221 gttaggaatc gcattgttac tttagtcata tacggaaggt gtaagtccgg atatattcag
     8281 aagaaaatgg aggaaaggaa tttgatgaaa ttcctttctg attgaaggaa aaaagttgaa
     8341 tcacatatgc ttttgtaaat ataagctaag ctccgttcga ttgttcattt gaagtttttc
     8401 cagtattctt gatacataat ttttgactgt gccttcagta ataaaaagtg cttcgcttat
     8461 agctttgttg cttttccctt ccataatctg tttagcgact tctttttctc tgggagtaag
     8521 caattgcacc agctgttcct tttcattatt ttcttgaaca agctctttat tatgttctac
     8581 cgaatttaga gcctttacaa cttttagcgt taccttagga tttaacagaa tattgccttc
     8641 acatgctgtt ttgatggaat caataatttc ttgtgaatca gaatctttca gtatgtaacc
     8701 atcagcaccg cttttcagtc cagtaaaaat gtattcacta tcattaaagg ttgtcaggat
     8761 aatcacttta atatccggat atctctcttt aactagcttt gttgcttcaa tgccgtccat
     8821 tatgggcatt cttatatcca ttaaaatgat ttcaggcctt atctgtttta gcaaatctaa
     8881 taaatgttca ccattagaag cttcgcctac aatattaatt tcctcgtgca gactcagaat
     8941 cattttaagc ccttccctga caatttgctg atcatccaca atgataatat ccatatcaat
     9001 acctcctcac attcggatta aagatctgct atctcgggga ttacggcttc cacagtaaat
     9061 cctgaatcta gccctgaatg aaaatcaacc tctcctccaa gtgcagcaaa tcttttctct
     9121 attcctttta ttccatttga cttattaatt tcagaacatc ctgttccgtt atcagttatc
     9181 gatatagaga ttttttcaaa agacttacgt attcttattg aaaaaaacgt agcatttcca
     9241 tgttttatcc cgttcgttat agactcttgt actgttttat agagacaatt cttgatatca
     9301 ggatcagctg actctacttt attgtccata tcaagctcga attttatttc atttgtttgc
     9361 tgaaaatttt caaaaatctc attgatcgat ttcagaagcc ctttttgagg agcagggtca
     9421 ttgagcaaag cgacagcttc tctcaggtta ataatacact ccttcgataa atcatgtgac
     9481 ttattgatga cttgtttagc ctcgctggga tttttactga ctattttatc ggcgaattca
     9541 agattcattg ttaatgcgat caaataatgc cctagggaat catgaagctc ttgtgcaatt
     9601 cttgtccgct ctttagaaat agttaactct tgaatctttt gagaataatt cttaagttta
     9661 gtgtttacac tttgtaattc tttatttaat gtttgtattt ttgctttttc gagcagtacg
     9721 tttctaaaca gataaataat agccatgatc actaaatagg acatcaatat atctttcccg
     9781 ctggtccctg ctgctttaag agctgtaaaa aaaataataa aatgcaggct tactacagtc
     9841 cagggcagtt tacgagttgt tacaataatc tcgatcagta agaaaatatt atatatttga
     9901 gaaccgagac agttaatttt aaacaataaa atgcctgata aaaggttact tactaaaaaa
     9961 gatgcataat atctaaaaga atactgaccg cttaggtatt ttaatctgat atgatcgttg
    10021 acgactaaaa aaatggtgat tatcagcagg taagcggatt ccgaagccgt gaaagttggc
    10081 gttttaaaaa tagaactgat aatagaatat aaggaaaaac aaataatggt tttttctatg
    10141 agcactcttg tactaattga agaaagattt ttcataataa tccttcctga gacaacttga
    10201 tataaattat attatacata tattgagaaa tcataaagcg acaac
//
