LOCUS       c00025_JADAQW0..       25412 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JADAQW010000045.1 Bacillus subtilis strain MD32
            NODE_5_length_354958_cov_59.183270, whole genome shotgun sequence.
ACCESSION   JADAQW010000045
VERSION     JADAQW010000045
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2022-06-21 13:47:17
            Original ID  :: JADAQW010000045.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 162437
            Orig. end    :: 187849
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25412
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[172437:177849]"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /neighbourhood="10000"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15412
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /neighbourhood="10000"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protocluster_number="1"
     cand_cluster    1..25412
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /kind="single"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..25412
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /region_number="1"
                     /rules="(minimum(3, [Amidohydro_1, Amidohydro_3, Arginase,
                     FGase, Urocanase]) and Lyase_aromatic and Urocanase_C)"
                     /tool="gutsmash"
     CDS             590..1927
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MmgE_PrpD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_172"
                     /sec_met_domain="MmgE_PrpD (E-value: 1.8e-93, bitscore:
                     307.9, seeds: 231, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKQGLTAGLAEAVRTSQPEHSVDATHEAKKGLLDFTAASFAGRE
                     DKGIQKLLCLIEDEGGLPLVPIIGQGKKAAPLQSAMLNGFIAHALDFDDVHSDVRGHPS
                     AVIVPALIASAARGHDERLLGAYIVGVEVMARLGESIGSRHYEKGWHNTGTLGAIAAAC
                     AVGYAEELTQEELEKAIGFAATQSAGMRVQFGTEMKPLHAGLAAQAGLLAVKLAQSEFG
                     GSRTAFDGETGFFSLYGDVEKAQHTLLNDWGAPWRIVQPGLWFKIYPFCSAAHHAADAV
                     RQLISEEAISAVNTERIEVIFPPGGDAALTERSPKTGEEGRFSVEYVIALALHGHELTV
                     EHFNSQPIPNGIQTTIGHIQRVYDNATQPAPHAVPKGRFTIVRAYLSDGRICEARVDCP
                     KGAPGNELSEEDIIEKLTLTVPQEKARRIITAVEKADIKEFLAHIE"
     CDS             1997..3109
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) EutH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_173"
                     /sec_met_domain="EutH (E-value: 4.6e-141, bitscore: 464.5,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVNDAVVFILAAFLLWGAADYCLGNRWGLGERFADGFKAMGPLA
                     LSMIGIVSLAPVLAAILIPIVAPFYTAIGADPSSFANTILAIDMGGYALAGEMAKDPQA
                     GLFSWVFLGTMMGPAIVFTIPVALGIIEKEDHPYFAKGILIGLCTVPIGCLIGGLCAGF
                     DIGMIGKNLLIPSLLSAMIAFGLWRYTDNMIQLFHLFGKAVSVVAIIGLAAVSVETMTG
                     IVLIPGMENVETGIQTTGTIAIALAGAFPMTAFITKTFKKPLQALGKHLHLDETATAGL
                     VTSLAHHIPMLASLKDMTPRGKVINVAFAVSGAFVLGSHLGFVAGMKKEMAAAMIIGKL
                     AGGVTAAAAAAWMTPAQSVNQQKRISAGHS"
     CDS             3182..4009
                     /locus_tag="ctg25_174"
                     /transl_table=11
                     /translation="MAVKDRYMSKIKQETKPWIKRFGRLGYFAFGGVFILLGVLAFMTA
                     AGAGRAKDSSGALQTLSRMPYGSLLLFLIGIGLIGYVIWMVLSAIKDTEGHGNSRRGLS
                     RRIGNFFSAAVYTSIAWNALRFVFGQGDGGTSEQTWSAYVLAQPFGQWLTGLTGVGFIV
                     FAIVQFMKGVRAAFMKEFDTSKMNKQMICITKNTGRAGNIARAIIFSAIGYFLIKTAMT
                     ADPDDTRGFDGALAELAQQPHGKLILSILALGLILYGMYAIMKGIYQHMTWEK"
     CDS             4143..5084
                     /locus_tag="ctg25_175"
                     /transl_table=11
                     /translation="MDREKQQLSIEAARLYYQSDYSQQQIAEQLKISRPTVSRLLQYAK
                     EKGYVQIRVMDPFEDLDALGSILEEKYGLLEAHVVFSPTPDYAGITHDLSRYGAEYMHE
                     TVKDGDIVGVSWGTTMYQIAQNMQPKQVKGVEVVQLKGGISHSRVNTYSAETIQLFAEA
                     FQTMPRYLPLPVVFDNADVKRMVEKDRHIERIIEMGKQANIALFTVGTVRDEALLFRLG
                     YFNEEEKALLKKQAVGDICSRFFDAKGNICSSAINDRTIGVELEDLRLKERSILVAGGS
                     RKVSSIHGALTGKYANVLIIDQHTARALVNDL"
     CDS             5190..5861
                     /locus_tag="ctg25_176"
                     /transl_table=11
                     /translation="MSLANIIDHTALKPHTQKAEILKLIEEAKTYKFASVCVNPTWVEL
                     AAKELKGTGVDVCTVIGFPLGANTTETKAFETKDAISKGATEVDMVINIAALKDKEDDV
                     VEADIRGVVEAAAGKALVKVIIETCLLTDEEKERACRLAVSAGADFVKTSTGFSTGGAT
                     KEDIALMRKTVGPDIGVKASGGVRTKEDVDTMVEAGASRIGASAGVSIVKGENASGGDN
                     Y"
     CDS             5942..7123
                     /locus_tag="ctg25_177"
                     /transl_table=11
                     /translation="MKYLIGIIGLIVFLGLAWIASSGKKRIKIRPIVVMLILQFILGYI
                     LLNTGIGNFLVGGFAKGFGYLLEYAAEGINFVFGGLVNADQTTFFMNVLLPIVFISALI
                     GILQKWKVLPFIIRYIGLALSKVNGMGRLESYNAVASAILGQSEVFISLKKELGLLNQQ
                     RLYTLCASAMSTVSMSIVGAYMTMLKPEYVVTALVLNLFGGFIIASIINPYEVAKEEDM
                     LRVEEEEKQSFFEVLGEYILDGFKVAVVVAAMLIGFVAIIALINGIFNAVFGISFQGIL
                     GYVFAPFAFLVGIPWNEAVNAGSIMATKMVSNEFVAMTSLTQNGFHFSGRTTAIVSVFL
                     VSFANFSSIGIIAGAVKGLNEKQGNVVARFGLKLLYGATLVSFLSAAIVGLIY"
     CDS             7153..8454
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_trans_3N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_178"
                     /sec_met_domain="Glycos_trans_3N (E-value: 1.2e-22,
                     bitscore: 74.0, seeds: 1422, tool: rule-based-clusters)"
                     /sec_met_domain="Glycos_transf_3 (E-value: 6.8e-54,
                     bitscore: 177.6, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRMVDIIIKKQNGKELTTEEIQFFVKGYTDGSIPDYQASALAMAI
                     FFQDMSDRERADLTMAMVNSGETIDLSAIEGIKVDKHSTGGVGDTTTLVLAPLVAALDV
                     PVAKMSGRGLGHTGGTIDKLEAIDGFHVELTKDEFIKLVNRDKVAVIGQSGNLTPADKK
                     LYALRDVTGTVNSIPLIASSIMSKKIAAGADAIVLDVKTGAGAFMKTEEDAAELAKAMV
                     RIGNNVGRQTMAVISDMSQPLGFAIGNALEVKEAIDTLKGEGPEDLHELVLTLGSQMVV
                     LAKKADTLDEARAKLEEVMKNGKALEKFKDFLKNQGGDSSIVDDPSKLPQAAYQIDVPA
                     KEAGVVSEIVADEIGVAAMLLGAGRATKEDEIDLAVGIMLRKKVGDKVEKGEPLVTLYA
                     NRENVDEVIAKVYDNIRIAAEAKAPKLIHTLITE"
     CDS             complement(8498..9862)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_permease"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_179"
                     /sec_met_domain="AA_permease (E-value: 7.4e-136, bitscore:
                     447.9, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISLGGVIGTGLFLSTGYTLHQAGPGGTILAYVIGGLMMYLVMQC
                     LGELSVAMPVTGSFQKYATTFIGPSTGFMVGIMYWINWVVTVGSEFTASGILMQRWFPD
                     SSVWMWSAIFAALLFICNAFSVKLFAETEFWFSSVKIVTIILFIILGGAAMFGLISLNG
                     TADAPMLSNFTDHGGLFPNGFLAVFIAMISVSFAFSGTELIGVTAGESANPQKDIPRSI
                     RNVAWRTVIFFIGAVFILSGLISWKDAGVIESPFVAVFAEIGIPYAADIMNFVILTALL
                     SVANSGLYASTRMMWSLANENMISSRFKKVTSKGIPLNALMISMAVSCLSLVSSIVAPG
                     TVYVVMVAIAGFAGVVVWMSIALSQLLFRKRFLKKGGDVKDLTFRTPLYPLMPIAALLL
                     CSASCIGLAFDPNQRIALFCGVPCIILCYLIYHFKRNVTKAKKISQEEYPADHIL"
     CDS             complement(10001..10960)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Arginase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_180"
                     /sec_met_domain="Arginase (E-value: 4.2e-68, bitscore:
                     224.3, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LDKYPFLREAGSSFKDRDVTKMSDLIATWDGQDIKGPALIGVPLS
                     KSSISHSGASFAPGTIRQALKHSSAYSAELGEHVVSELLYDLGDIDIHVTDIVKSHHHI
                     FQTMHALLSDHPDWVPLILGGDNSISYSTIKAIAQTKGTTAVIQFDAHHDVRNTEDGGP
                     TNGTPFRRLLDEEIIEGQHLIQLGIREFSNSQAYEAYAKKHNVNIHTMDMIREKGLIST
                     IKEVLPAVQNRTDFIFISVDMDVLDQSHAPGCPAIGPGGLYTDELLEAVKYIAQQPNVA
                     GIEIVEVDPTLDFRDMTSRAAAHVLLHALKGMKLSPFK"
     CDS             complement(10953..12218)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Amidohydro_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_181"
                     /sec_met_domain="Amidohydro_1 (E-value: 3.1e-20, bitscore:
                     67.2, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKQIDTILINIGQLLTMESSGPRAGKSMQDLHVIEDAVVGIHEQ
                     KIVFAGQKGAEAGYEADEIADCSGRLVTPGLVDPHTHLVFGGSREKEMNLKLQGISYLD
                     ILAQGGGILSTVKDTRAASEEELLQKAHFHLQRMLSYGTTTAEVKSGYGLEKETELKQL
                     RVAKKLHESQPVDLVSTFMGAHAIPPEYQNDPDEFLDQMLSLLPEIKEQELASFADIFT
                     ETGVFTVSQSRRYLQKAAEAGFGLKIHADEIDPLGGAELAGELKAVSADHLVGASDEGI
                     KKLAEAGTIAVLLPGTTFYLGKSTYAKARAMIDEGVCVSLATDFNPGSSPTENIQLIMS
                     IAALHLKMTAEEIWHAVTVNAAYAIGKGEEAGQLKVGRSADLVIWQASNYMYIPYHYGV
                     NHVHQVMKNGTIVVNREGAIFG"
     CDS             complement(12231..13889)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Urocanase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Urocanase_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Urocanase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_182"
                     /sec_met_domain="Urocanase (E-value: 3.1e-91, bitscore:
                     299.1, seeds: 148, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_C (E-value: 7.5e-96, bitscore:
                     313.7, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_N (E-value: 6.5e-63, bitscore:
                     204.6, seeds: 71, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDVKKSIRANRGTELECLGWEQEAVLRMLRNNLDPEVAEKPEDL
                     IVYGGIGKAARDWDAFHAIEHSLKTLKNDETLLVQSGKPVGMFRTHPQAPRVLLANSVL
                     VPKWADWEHFHELEKKGLMMYGQMTAGSWIYIGSQGILQGTYETFAELARQHFGGSLKG
                     TLTLTAGLGGMGGAQPLSVTMNEGVVIAVEVDEKRIDKRIETKYCDRKTASIEEALAWA
                     EEAKLAGKPLSIALLGNAAEVHHTLLNRGVKIDIVTDQTSAHDPLIGYVPEGYSLDEAD
                     RLRQDNPELYVRLAKQSMKKHVEAMLAFQQKGSIVFDYGNNIRQVAKDEGLENAFDFPG
                     FVPAYIRTLFCEGKGPFRWAALSGDPADIYRTDALLKELFPTNKALHRWIDMAQEKVTF
                     QGLPSRICWLGYGERKKMGLAINELVRTGELKAPVVIGRDHLDCGSVASPNRETEAMKD
                     GSDAVGDWAVLNALVNTAAGASWVSFHHGGGVGMGYSLHAGMVAVADGSELADERLARV
                     LTSDPGMGIIRHADAGYERAVEVAKKQDIIVPMQK"
     CDS             complement(13886..15412)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Lyase_aromatic"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_183"
                     /sec_met_domain="Lyase_aromatic (E-value: 8.8e-197,
                     bitscore: 648.7, seeds: 479, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTLDGSSLTTADVARVLFDFEEAAASEESMERVKKSRAAVERIV
                     RDEKTIYGINTGFGKFSDVLIQKEDSAALQLNLILSHACGVGDPFPECVSRAMLLLRAN
                     ALLKGFSGVRAELIEQLLAFLNKRVHPVIPQQGSLGASGDLAPLSHLALALIGQGEVFF
                     EGERMPAMTGLKKAGIQPVTLTSKEGLALINGTQAMTAMGVVSYIEAEKLAYQTERIAS
                     LTIEGLRGIIDAFDEDIHLARGYQEQIDVAERIRFYLSDSGLTTSQGELRVQDAYSLRC
                     IPQVHGATWQTLGYVKEKLEIEMNAATDNPLIFNDGDKVISGGNFHGQPIAFAMDFLKI
                     AISELANIAERRIERLVNPQLNDLPPFLSPHPGLQSGAMIMQYAAASLVSENKTLAHPA
                     SVDSIPSSANQEDHVSMGTIAARHAYQVIANTRRVIAIEAICALQAVEYRGIEHAASYT
                     KQLFQEMRKVVPSIQQDRVFSYDIERLTDWLKKESLIPDHQNKELRGMNI"
     CDS             complement(15525..15980)
                     /locus_tag="ctg25_184"
                     /transl_table=11
                     /translation="VIHMTLHKERRIGRLSVLLLLNEAEESTQVEELERDGWKVCLGKV
                     GSMDAHKVVAAIETASKKSGVIQSEGYRESHALYHATMEALHGVTRGEMLLGSLLRTVG
                     LRFAVLRGNPYESEAEGDWIAVSLYGTIGAPIKGLEHETFGVGINHI"
     CDS             16565..17983
                     /locus_tag="ctg25_185"
                     /transl_table=11
                     /translation="MFNRLFRVCFLAALIMAFTLPNSVYAQKAGKPVFTEVSVHDPSII
                     ETNGTLYVFGSHLASAKTNDLMQWQQLTTSVSNDNPLIPNVYEELKDTFEWAQSNTLWA
                     ADVTQLADGKYYMYYNACRGDSPRSAMGVAVADNIEGPYKNKGIFLKSGMEGTSSDGTP
                     YDATKHPNVVDPHTFFDKDGKLWMVYGSYSGGIFILEMNPKTGFPLPGQGYGKKLLGGN
                     HSRIEGPYVLYNPDTQYYYLYLSYGGLDATGGYNIRVARSKKPDGPYYDAEGNPMLDVR
                     GKEGTFFDDRSIEPYGVKLMGSYTFETENEKGTGYVSPGHNSAYYDQKTGRSYLIFHTR
                     FPGRGEEHEVRVHQLFMNKDGWPVAAPYRYAGETLKEVKQKDITGTYKLIQHGKDISAD
                     IKKTINIQLNKDHTISGEMTGTWKKTGKNTADITLAGKKYNGVFLRQWDSVREKNVMTF
                     SVLNGSGEAVWGSK"
     CDS             18019..18111
                     /locus_tag="ctg25_186"
                     /transl_table=11
                     /translation="MSFIDYKKWLSERKNRSDSGVQDLNEKSPS"
     CDS             18288..18653
                     /locus_tag="ctg25_187"
                     /transl_table=11
                     /translation="MHSEMLLHSVKADLHEKQEQIHQLKRVLHEIRQIKHEFSEAQHLI
                     HRPHLNREAWRGTHAERFEDIREGMNKAYQQIKSEQVSGIIESIEGKIHSLEGDVYSIR
                     RQITRIEHEIEKEKHKK"
     CDS             18665..18934
                     /locus_tag="ctg25_188"
                     /transl_table=11
                     /translation="MAQEIKMVYGTVKQGLSQLKNSAELKSSLPGHLSGRNHLNVVKSI
                     EQLNKDIKELTEAYASVLAKHIAQTESAVNAMKETDENISSSMK"
     CDS             18954..20519
                     /locus_tag="ctg25_189"
                     /transl_table=11
                     /translation="LKTLDVHALHEGIQHTIEKLDKQKQQLEKLEKSVEHLAGMKDALK
                     GKGGDAIRTFYEECHKPFLLFFGMFIGEYKKVLKQTQHAISSVESDSHGMIAEAFLSHD
                     ARHGVKHAREVTEQLTDAVNRQTSAIDHIVSLPAVNDTFFRMETEQAERLISDTLNKLF
                     QFDGQQTQALETAKSDFQTMKKYIDQLETMYTGPKIEITGYKSGSILKSQEEENINQTF
                     GAINPQMKQADDSPMEMMLKKLAENEKSKVDSVVKTGHSKKVSKNIIVINGKVYNTSEH
                     REHIKTDFSNAEVKQVVYNDTLYNVYISGNDMKLEPVVSLSDIKVDENGYVKILETAVE
                     FSGINDLFRAATGRDPITGEKVSSKDRIVATVHAVPISKIAKLQKFNIYKLINGEIKTK
                     KASKIEKGTKKNKNDKVLTKNGAFRDAKRRAGIPNSSQHKKPVDVFDGTSENRRVYEFE
                     VDGKKKYIIEHREDKLGRGPHFHGADDLKGNPLEKGRYNQYPGHSPEDFEGYKNKGKFK
                     KKGD"
     CDS             20547..21017
                     /locus_tag="ctg25_190"
                     /transl_table=11
                     /translation="MELLKRKSRRKNLIRELDFLHITEDSFLDIEENELFCKKAFSILD
                     TKQNKVQIQGTDYIENIQKSIQLLKDTFENVELGSNEARLLFFRENEIEAVLLSLDEIF
                     INLDKVLEITKFSIGYGDFILTSEDFKFGLCIERTEYHYEFCVWGLSKKNKK"
     CDS             22440..24269
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTS_EIIC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_191"
                     /sec_met_domain="PTS_EIIC (E-value: 3.7e-39, bitscore:
                     129.0, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYDKLSKDILQLVGGEDNVQRVIHCMTRLRFNLHDNSKADRSQL
                     EQLPGVMGTNISGEQFQIIIGNDVPKVYQAIVRHSNLSDEKSAGSSSQKKNVLSAVFDV
                     ISGVFTPILPAIAGAGMIKGLVALAVTFGWMAEKSQVHVILTAVGDGAFYFLPLLLAMS
                     AARKFGSNPYVAAAIAAAILHPDLTALLGAGKPISFIGLPVTAATYSSTVIPILLAIWI
                     ASYVEKWIDRFTHASLKLIVVPTFTLLIVVPLTLITVGPLGAILGEYLSSGVNYLFDHA
                     GLVAMILLAGTFSLIIMTGMHYAFVPIMINNIAQNGHDYLLPAMFLANMGQAGASFAVF
                     LRSRNKKFKSLALTTSITALMGITEPAMYGVNMRLKKPFAAALIGGAAGGAFYGMTGVA
                     SYIVGGNAGLPSIPVFIGPTFIYAMIGLVIAFAAGTAAAYLLGFEDVPSDGSQQPAVHE
                     GSREIIHSPIKGEVKALSEVKDGVFSAGIMGKGFAIEPEEGEVVSPVRGSVTTIFKTKH
                     AIGITSDQGAEILIHIGLDTVKLEGQWFTAHVKEGDKVAPGDPLVSFDLEQIKAAGYDV
                     ITPVIVTNTDQYSFSPVKEIGKVQTKEALLALS"
ORIGIN
        1 tcgtcatcaa agggaaaggc ggacacgccg gcatcccgaa taacagtatt gatccaatcg
       61 ctgcagccgg acaaatcatc agcgggctgc aatctgtggt cagccgcaat atcagctcac
      121 tgcaaaacgc agtcgtcagt atcacaagag tacaggcggg cacgtcgtgg aacgtgattc
      181 cagaccaagc tgaaatggag gggacggttc gaacctttca aaaagaagcg cggcaggctg
      241 ttccggagca tatgagacga gtggctgaag gaattgcagc gggctatggg gcacaagcag
      301 aattcaagtg gtttccttat ttgccttccg ttcagaatga cggcacgttt ttgaatgcgg
      361 catccgaagc tgcggcacgg cttggctatc aaaccgttca cgctgagcag tctccgggcg
      421 gagaagactt cgctctgtat caagagaaga ttccgggatt ttttgtctgg atgggaacga
      481 acgggacgga ggagtggcat catccggcct ttacactgga tgaagaagcc cttacggttg
      541 cctctcagta ctttgcggag ctggcggtta ttgtattgga gaccatcaaa tgagcaaaca
      601 agggctgaca gcaggtcttg cagaggctgt gagaacgtca caacctgagc attcagttga
      661 cgcgactcac gaagcaaaaa aaggattact tgattttact gccgcttcat tcgcaggaag
      721 agaagataaa ggaattcaaa agctcctctg tctgatagag gatgaaggag gcctgcccct
      781 tgttcctatt atcggacagg gcaaaaaggc cgcgccatta caatccgcga tgctcaatgg
      841 atttatcgcc catgcattgg attttgatga tgtccactcc gatgtaagag gacaccccag
      901 tgcagtcatc gtgccggccc ttattgcatc tgccgctcgc ggacatgacg agcggcttct
      961 tggcgcttat attgttggtg ttgaagtgat ggcacggctg ggagaatcaa ttggcagccg
     1021 ccactatgaa aagggctggc ataatacagg aacgcttggt gccatcgctg ctgcctgcgc
     1081 cgtaggttat gctgaggagc tgactcagga agagctggaa aaagcgattg gttttgcggc
     1141 tacgcaatct gctgggatga gggtgcaatt tggaacagaa atgaaaccgc tgcacgccgg
     1201 tctggcggct caggctggct tactggccgt taagctggcc caatcagaat ttggcgggtc
     1261 ccgcacggca tttgatggag aaactggttt cttcagtctg tacggtgacg ttgaaaaagc
     1321 acaacatact ttgctaaacg attggggggc accctggaga atcgtgcagc cgggtctatg
     1381 gtttaaaatc tatccatttt gttccgcggc acaccatgct gcagatgcgg tacgacagct
     1441 tatctccgaa gaagccattt ctgctgtcaa tactgaacgt attgaagtga tttttccgcc
     1501 aggcggagat gctgcattga cggaaagatc tccaaaaact ggagaggaag gtcgtttcag
     1561 cgttgaatat gtgattgctc ttgctttgca cggacacgag ctgaccgttg aacatttcaa
     1621 cagccagccg atcccaaacg gcattcaaac gacaataggg catattcagc gcgtatatga
     1681 caatgctact cagccggctc cccatgccgt tccaaaaggc cgtttcacga ttgtccgggc
     1741 ctatttatca gacggccgga tttgcgaagc gcgtgtggac tgcccaaaag gggcgccagg
     1801 aaatgagctg tctgaagaag acataataga aaaattgaca ttaacggtcc cgcaagaaaa
     1861 agcgcggcgc atcataacag ccgttgaaaa agccgatata aaagaatttt tagctcatat
     1921 tgaataagat caactctatt cggtgatttc agatgatatg ataaaaccaa tcatacgttt
     1981 gaaaaaggag aaaaccatga cggtgaatga cgcggttgta ttcattttgg ctgccttttt
     2041 actatgggga gcggcggatt attgtttggg aaacagatgg gggctaggcg agcggtttgc
     2101 ggacggcttt aaggctatgg ggccgctggc gctgtccatg atcggaattg tgtcgctggc
     2161 gcccgtgctg gcagcaatcc tgattcccat tgttgctccg ttttacacag cgattggcgc
     2221 ggacccttct tcctttgcga acaccatttt ggcgattgat atgggaggat atgcgctggc
     2281 tggagaaatg gcgaaagatc cgcaggccgg gctgttttca tgggtgtttt taggaacaat
     2341 gatgggacct gcaatcgtct tcacgattcc cgtcgctctt ggcatcatcg aaaaagagga
     2401 tcatccgtat tttgcgaaag gaatattaat cgggttgtgc acagtgccga tcggttgctt
     2461 aatcggcgga ttatgcgcag gctttgacat cggcatgata ggtaaaaatc ttctgatccc
     2521 gagtctgtta tctgctatga tcgcttttgg gttatggcga tacaccgaca atatgattca
     2581 gttgtttcat ctcttcggga aagcggtcag tgtggttgcg attatcgggc ttgcggctgt
     2641 ctccgttgaa acgatgaccg gcattgtgct gattccggga atggagaatg tcgagacagg
     2701 gatacaaacg acagggacca tcgccattgc cctggcaggg gcgttcccga tgacggcttt
     2761 tattacaaaa acctttaaaa aaccgcttca ggccctgggg aaacaccttc atttagatga
     2821 gacagcaaca gcaggattgg tgacctcttt ggcgcatcat attccaatgc tggcttcatt
     2881 aaaagatatg acgccgagag gaaaggtcat caatgtcgcg tttgcggtca gcggcgcctt
     2941 tgtactcggc agccatcttg gttttgtggc tggaatgaaa aaagaaatgg cggcggccat
     3001 gatcattggg aaattagcag gcggagtcac agctgccgca gcggctgctt ggatgacacc
     3061 tgcacaatca gttaatcagc aaaaacgtat ctcagccggc catagctgag gcagaagctg
     3121 tttcaacttt gtccaattgg gaatgttaca gtaaagactt ctgtgaaaga gggttggaca
     3181 catggcggtg aaagaccggt acatgtcaaa aataaaacag gaaaccaagc cttggatcaa
     3241 gcgatttggg aggcttggtt attttgcatt cggcggtgtt tttattctgc ttggggtttt
     3301 ggcctttatg acggctgccg gggcaggccg cgcgaaagat tcgagcggag ctctccaaac
     3361 gctatcacgc atgccgtatg ggtcactatt gcttttttta ataggcatcg gccttatcgg
     3421 ctatgtgatc tggatggtgt taagcgcgat caaggacacg gaggggcacg gaaacagcag
     3481 gcgaggcctg tcacggagaa taggaaactt tttcagtgcc gccgtttaca catccatcgc
     3541 ttggaatgcc ttgcgatttg tgtttggcca aggggacggc ggcacttcag aacagacgtg
     3601 gtccgcttat gtattggcgc agccgttcgg ccaatggctc acagggctta cgggtgtggg
     3661 ttttatcgta tttgcgattg ttcaatttat gaaaggtgtt cgggctgctt ttatgaaaga
     3721 atttgatacg tcaaaaatga acaaacaaat gatatgcatc acaaaaaaca ccggacgcgc
     3781 aggcaatatc gcccgggcca ttattttctc ggctatcggc tattttctca tcaagacagc
     3841 catgaccgct gatcctgacg acacaagagg ctttgacggt gcgctcgccg aactcgcgca
     3901 gcagccgcat ggcaaattga ttctgtctat attggcatta ggcctgatcc tatatggaat
     3961 gtacgccatt atgaaaggca tttatcagca tatgacctgg gagaagtaag ctctgggcag
     4021 gtccgcgccc agagcgtttt tcagtttctt agaaatcagg tggatgaaag ccggcgccag
     4081 cctgtataat aaaagcaaat caaaagcagt tttatcagga ctgatccaca gggaggtgca
     4141 gaatggatcg ggaaaaacaa caattaagca tagaagcggc aaggctttac tatcagtctg
     4201 actacagtca gcagcaaatt gctgagcagc tcaagatttc aaggccaacc gtttcccggc
     4261 tgctgcaata tgcaaaggaa aaagggtatg ttcagattcg cgtcatggac ccttttgagg
     4321 atttggatgc gctcggttcc atacttgaag agaaatacgg gctccttgag gcgcatgttg
     4381 tgttttcccc gacacccgat tatgcaggaa ttacacatga cctaagccgc tatggtgcag
     4441 aatatatgca tgaaacggta aaagacggcg acattgtcgg cgtcagctgg ggaaccacca
     4501 tgtatcaaat cgcgcaaaac atgcagccga agcaggtaaa aggcgtcgag gtcgtccagc
     4561 taaaaggcgg catcagccat tcccgggtaa acacgtattc ggctgaaacg attcagctgt
     4621 ttgcagaggc ttttcaaacg atgccgcgct atctcccgct tcccgtcgtg tttgataatg
     4681 cggatgtgaa gcgaatggtg gagaaagacc gtcatattga gcgaatcatc gagatgggaa
     4741 agcaggcgaa tatcgctctc ttcacggtgg ggactgtccg tgacgaagcg ctgttgttcc
     4801 ggctcggata ttttaacgaa gaagagaaag ccctgctgaa aaaacaggcc gtaggggata
     4861 tttgttcacg cttttttgat gcgaaaggga atatttgcag cagcgccatc aatgaccgga
     4921 ccatcggtgt tgagcttgaa gacctcagac tgaaggaacg ctccatttta gttgccggcg
     4981 gaagcagaaa agtatcttcc attcacggag cattaaccgg aaaatatgcc aacgttttaa
     5041 tcattgacca gcataccgcg agggcgcttg ttaatgattt gtgacacgtt caaacctttc
     5101 attgaacaaa atttcaatta ccaatttaca tatgttcaaa agtcggttat gctaaaaaat
     5161 atcttaacaa aaaaggaagt gtgcgaagga tgtcattagc caacataatt gatcatacag
     5221 ctttgaaacc gcatacacaa aaagcggaaa ttctaaaact aattgaagaa gcgaaaacat
     5281 acaaatttgc ttcagtatgt gtcaatccga catgggtgga gcttgctgca aaagagctta
     5341 agggaactgg agtcgacgtt tgtacggtca tcggcttccc gctcggtgcc aatacaactg
     5401 aaacaaaagc gttcgaaaca aaagacgcca tttcaaaagg cgccactgaa gtggatatgg
     5461 tcattaatat tgccgcttta aaagacaagg aagacgatgt ggtggaagct gatatccgcg
     5521 gtgtagtaga agctgcagcc ggaaaagcgc ttgtcaaagt cattatcgaa acatgccttc
     5581 tgactgatga agaaaaagaa cgtgcatgcc gtttagcggt gtctgcggga gcggatttcg
     5641 taaaaacatc aacaggcttt tctacaggag gcgcaacgaa ggaagatatc gccttaatgc
     5701 gcaaaacagt aggacctgat atcggcgtga aagcatctgg cggcgtcaga acgaaagaag
     5761 atgtagacac aatggttgag gccggagcca gccgaattgg cgccagcgca ggcgtttcca
     5821 tcgtaaaagg agaaaatgca tcaggcggag acaactatta agagctgacg gaaggcagac
     5881 tgctttccgt tttctgggga aacagtagtt gtaagcgaat acaaataaag gagaaacaca
     5941 tatgaagtat ttgattggga ttatcggttt aatcgtgttt ttaggcctcg cgtggatcgc
     6001 gagcagcggc aaaaaaagaa ttaagatccg cccaattgtt gttatgctca ttttgcaatt
     6061 tattcttggc tacattctcc tcaataccgg aatagggaat ttcctcgtgg gaggatttgc
     6121 aaaaggattc ggttacctgc ttgaatacgc ggcagaggga attaactttg tgtttggcgg
     6181 cttggtgaat gcggaccaaa cgacattctt tatgaatgtt ctcttgccga tcgtgtttat
     6241 ttccgctctg atcgggattc tgcaaaagtg gaaagtcctc ccgtttatta ttagatatat
     6301 cggtcttgcc ctcagcaagg taaacggtat gggaagattg gaatcgtata acgcagtggc
     6361 ttctgcgatt ttagggcagt cagaagtatt tatctccttg aagaaagaac tcggtctttt
     6421 aaatcagcag cgcttgtaca cgctttgcgc atctgcgatg tcaactgtat caatgtcgat
     6481 tgtcggcgcg tatatgacaa tgctgaaacc ggaatatgtt gtaacagcgt tggtcttgaa
     6541 cttatttggc ggtttcataa ttgcttctat tatcaatccg tacgaggttg caaaagaaga
     6601 ggatatgctt cgtgttgagg aagaagaaaa acaatccttc ttcgaagtgc tcggagaata
     6661 catccttgac ggtttcaaag tagcggttgt cgtcgctgcg atgctgattg gatttgtcgc
     6721 gattattgcc ttgatcaatg gcatttttaa tgcagtattc ggtatttcgt tccaaggcat
     6781 ccttggatat gtgtttgctc cattcgcttt tcttgtgggt atcccatgga atgaagctgt
     6841 taatgcggga agcattatgg caacaaaaat ggtatcgaat gaatttgtcg ccatgacgtc
     6901 gcttacgcaa aacggtttcc atttcagcgg ccgtacaaca gcgatcgtat cggtattcct
     6961 tgtgtcattt gcgaacttct cctcaatcgg aatcattgcc ggtgccgtaa aaggactgaa
     7021 tgaaaagcaa ggaaatgtcg tcgctcgttt cggcttgaaa ttattatacg gtgctacgct
     7081 tgtcagcttt ttatcagcag caattgtggg cttgatttac tgaacttaat cgaaaaggat
     7141 cggtgaccaa acatgagaat ggtagatatc atcatcaaaa aacaaaacgg aaaagaactc
     7201 accactgaag aaattcaatt tttcgtgaaa ggctatacag acggaagcat tcctgattat
     7261 caggcaagcg cgcttgctat ggcgattttc ttccaggata tgagtgatcg tgaacgcgcg
     7321 gacttgacga tggctatggt gaactccggt gaaacgattg atctttctgc cattgaagga
     7381 attaaagtgg ataaacactc caccggcggc gtcggcgaca caacaacact cgttctcgct
     7441 ccgcttgttg cggctcttga cgtgccggtt gccaaaatgt ccggccgcgg cctcggccat
     7501 acgggcggca cgattgataa gttagaggca atcgacggct tccacgtgga actgacgaag
     7561 gatgaattta ttaaacttgt gaaccgcgac aaggttgcgg tcatcggcca aagcggcaat
     7621 ttaacgccgg ctgataaaaa actgtacgcg cttcgtgatg taacgggaac ggtcaattcc
     7681 attccgctca ttgcaagctc gattatgagt aaaaaaatcg ctgccggggc ggacgcaatc
     7741 gtgcttgacg taaaaacggg agcgggcgcc ttcatgaaaa cagaagaaga cgcagctgaa
     7801 cttgccaaag cgatggtacg catcggaaat aacgtcggcc gtcagacaat ggctgtcatt
     7861 tcagacatgt cccagccgct cggctttgcg atcggaaatg cgcttgaagt caaagaagcg
     7921 atcgacacgc tcaaaggcga gggacctgag gatcttcatg agcttgtctt aacgctcggc
     7981 agccagatgg ttgtgcttgc gaaaaaagcc gatacattgg acgaagcgag agcgaagctg
     8041 gaagaagtca tgaaaaacgg caaagcgctt gagaaattca aggatttcct gaaaaaccaa
     8101 ggcggcgaca gctcaattgt tgacgatccg tctaagcttc cgcaagccgc atatcaaatt
     8161 gatgtgcctg ccaaagaagc gggtgtcgtc tctgaaatcg ttgcggacga aatcggcgtc
     8221 gcggcgatgc tgttaggtgc cggccgtgcc acaaaagaag atgagatcga tttagccgtc
     8281 ggcatcatgc tccgcaaaaa ggtcggcgac aaagtagaaa aaggcgaacc gctcgtgacg
     8341 ctttacgcca accgcgaaaa cgttgatgaa gtcatcgcaa aagtctatga caacatccgc
     8401 atcgccgcgg aagcgaaggc gccgaagctg attcatacgt tgattacaga ataaaaaata
     8461 aagcacatcc catactgagc ggggtgtgct tttttaatta taggatgtga tcggctggat
     8521 attcctcttg gctgattttt ttcgcttttg taacatttct tttgaaatgg tagatgagat
     8581 agcaaaggat gatacaagga actccgcaga aaagtgcgat tctttgattg ggatcaaaag
     8641 caagaccgat acaagaagca gaacataata agagagcggc tataggcata agaggataaa
     8701 gcggcgtgcg aaatgtcaga tcttttacat cccccccttt tttcagaaat ctctttcgaa
     8761 acaagagttg ggacaaggca atgctcatcc agaccacgac tcctgcaaat ccagcaattg
     8821 cgaccatcac aacatagaca gttccagggg ccacgatact ggaaacgaga gataaacaag
     8881 atacagccat actgatcatt aaggcattta aaggaatgcc tttagatgtc actttcttaa
     8941 aacgggagct gatcatgttt tcatttgcta acgaccacat catacgggtc gaggcatata
     9001 agcctgagtt ggcgacagac agcaaggctg ttaatatcac gaaattcata atatcagcag
     9061 cgtaagggat tccgatctcc gcaaatacgg ctacaaacgg gctttcaatc acgcctgcgt
     9121 ccttccacga aatcaatccg gataatatga agacagcgcc aatgaaaaaa atcacggttc
     9181 tccatgcgac attacggatg gatcgcggta tatccttttg aggatttgct gattctcctg
     9241 ctgtaacgcc gattaactct gtaccggaaa aggcgaagct cacagatatc attgcgataa
     9301 aaacggcgag aaagccattc ggaaacagcc cgccatggtc cgtgaagttt gacaacatag
     9361 gagcatccgc cgttccgttt aaagagatca ggccaaacat agcggctcct cccaaaatga
     9421 taaataaaat aatggtgaca atctttacgc ttgaaaacca aaattcagtc tccgcaaata
     9481 acttaactga aaatgcgttg catataaaaa gaagggctgc aaaaatcgca ctccacatcc
     9541 atacactgct gtcagggaac cagcgctgca tgagaatacc ggatgcggta aactcagagc
     9601 ctaccgtcac cacccaattg atccagtaca tgatgccgac cataaaaccg gtagatggac
     9661 cgataaatgt tgtagcatat ttttgaaaag agccggtcac cggcatggca accgacaatt
     9721 cgccgagaca ttgcatgacg aggtacatca tcaacccgcc gattacataa gcgagtatcg
     9781 taccgccggg tccggcttga tgtagcgtat agcccgtact gaggaaaagt cctgtgccta
     9841 tgacgcctcc caatgagatc ataaataggt gcctgctttt cattgtgcgt tttagctgtt
     9901 ggctgctgtt ctcctgaaga ttcactgtct cgccctcctt ttagctgcca ttcctaaggc
     9961 agatgagttt cttataccca aaatacaacc tgccagaaga tcacttgaat ggggagagtt
    10021 tcattccttt taatgcgtgt aacagaacat gagctgcagc tctgcttgtc atatctcgaa
    10081 aatcgagggt aggatcgact tcaacaattt caatcccggc aacattgggc tgttgtgcga
    10141 tgtacttgac tgcttcaagc aattcgtctg tatagaggcc gcccgggcca atcgctggac
    10201 agccgggtgc atgggactgg tctaagacat ccatgtcaac agatataaaa atgaaatctg
    10261 ttctattttg aacggctggc aaaacctctt ttatcgtgga gatgagtcct ttttcccgga
    10321 tcatgtccat cgtgtgaatg ttcacgttat gtttttttgc atatgcttca taggcctggc
    10381 tgttgctgaa ttctctgata cccagctgga tcaaatgttg accttcaatg atctcttcat
    10441 ccaaaaggcg gcggaagggg gtgccgtttg tcggcccccc gtcctccgta ttgcgaacat
    10501 cgtgatgggc atcaaattga atcaccgctg tcgttccttt tgtttgtgct atcgctttta
    10561 ttgtggagta gctgatagag ttatctcccc caagtatgag cggcacccaa tccggatgat
    10621 ccgaaagcag agcgtgcatg gtttggaaaa tgtgatgatg tgactttacg atatcagtga
    10681 catgaatatc gatatccccc agatcatata gaagctctga tacgacatgc tctccaagct
    10741 cagcagaata ggctgatgaa tgtttcagag cctggcgtat tgttccgggt gcaaaggaag
    10801 cgcctgaatg actgatggag gattttgata gggggacacc tatcaacgcc ggtcccttaa
    10861 tgtcttggcc gtcccatgtt gcgatcaggt cgctcatttt tgtgacatcc cggtccttaa
    10921 acgaagaccc agcctctctg agaaaagggt acttatccaa aaatagctcc ctccctgttg
    10981 acaacaattg ttccgttttt catgacttga tgtacatgat tgaccccgta gtgatacgga
    11041 atatacatat agttcgaggc ttgccaaatg actagatcag ctgagcggcc gactttgagc
    11101 tgaccggctt cctctccttt ccctatggcg tatgcggcat tgactgtgac cgcatgccat
    11161 atttcttctg cagtcatttt cagatgaagc gcggcaatgg acataatcag ctggatattt
    11221 tcagtcggcg agctgccagg attaaaatcc gttgccaagc tgacacatac accttcatca
    11281 atcatagctc tagccttggc gtatgtgctt ttgccaagat aaaatgtcgt gcccggcaag
    11341 aggacggcga tcgttcctgc ctcagccaat ttctttatgc cttcgtccga tgcacctacc
    11401 aaatggtcgg ctgagacggc ctttagctca cctgctaatt cagcacctcc aagcggatcg
    11461 atttcatctg cgtgtatttt taatccgaag cctgcctcag ctgctttttg taaataacgg
    11521 cgggattggc tgactgtaaa aacgcctgtt tctgtaaaaa tatcagcaaa gctggcgagc
    11581 tcctgctctt tgatttccgg caaaagggaa agcatttgat ccagaaattc atctggatcg
    11641 ttttgatatt cgggaggaat cgcatgggct cccataaatg tggaaacaag gtcaacaggc
    11701 tggctttcat gcagtttctt tgcgacacgc aactgtttga gctctgtctc tttttccaag
    11761 ccgtagccgc ttttcacttc tgctgtggtt gtgccgtagg acagcattct ttgcagatga
    11821 aaatgggctt tttgcagcag ctcttcttct gaagccgccc tggtatcctt gactgtagac
    11881 agaattccgc cgccctgcgc cagaatatcc aaatatgaaa tgccctgaag cttaaggttc
    11941 atctcctttt cacgagatcc gccaaataca agatgggtgt gcggatcaac gaggccaggc
    12001 gttacaaggc gtcccgaaca gtcagcgatt tcgtctgcct cgtaaccggc ttcagcccct
    12061 ttttgtccgg cgaacacaat tttctgttca tggatgccga caacagcgtc ttcgatcaca
    12121 tgaagatcct gcatgctttt gcctgcccgc gggccgctgc tttccatcgt caaaagctga
    12181 ccgatgttga tgagaatcgt atcaatttgc tttggcatgt catcactcct ttatttttgc
    12241 atcggcacga taatgtcctg ttttttcgct acttcaacgg cacgttcata acccgcatcc
    12301 gcatgacgga taatgcccat tcctgggtcg ctcgttaaga cccgcgcgag ccgctcgtca
    12361 gccagctcac ttccatcggc cactgcaacc atgccggcat gcagggaata gcccattccg
    12421 acgccgccgc catggtggaa ggaaacccag cttgcacccg ccgccgtgtt gacaagcgca
    12481 tttagcacag cccaatcacc gacagcgtca cttccgtcct tcatcgcttc tgtctcccgg
    12541 tttggagagg cgacagaccc gcagtccaaa tgatctctcc caataacgac aggcgctttt
    12601 agctccccgg ttctaaccag ctcgttaatg gcgaggccca tcttttttcg ttctccatat
    12661 ccaagccagc aaatacggga cggcaagcct tggaaggtga ctttttcctg tgccatatca
    12721 atccagcggt gaagggcttt atttgttggg aacagctctt ttaataacgc atccgtacgg
    12781 taaatatctg ccggatctcc ggaaagcgcc gcccagcgga acggcccttt tccttcacag
    12841 aataaggtgc ggatgtaggc agggacaaac cccggaaaat cgaaggcatt ctccagccct
    12901 tcatcctttg cgacttgccg gatattgttg ccgtagtcaa atacaataga gcccttttgc
    12961 tgaaaggcca gcatggcttc gacatgtttt ttcatgcttt gcttcgcaag gcgcacgtaa
    13021 agctctggat tgtcttgacg caaacggtca gcttcatcaa gtgaatagcc ctcgggaaca
    13081 taaccgatta aagggtcatg ggcagatgtc tgatctgtca caatatcaat tttgacgcct
    13141 cggttcaaaa gtgtgtgatg cacctcagct gcgtttccga gaagtgcaat ggacaaaggt
    13201 tttcctgcca gctttgcctc ttcagcccaa gctaaggctt cctcaatcga tgctgttttt
    13261 cgatcgcagt attttgtttc gatccgcttg tcgatgcgtt tttcgtcaac ctcgacagca
    13321 atgacgacgc cttcattcat cgtgacagac agcggctgtg cgcctcccat tccgccgaga
    13381 cccgctgtca gcgtcaatgt tccttttaag ctgcctccaa agtgctgtcg cgccagctca
    13441 gcgaaggttt cataggttcc ttgcaatatg ccttgtgagc caatgtaaat ccagctgcca
    13501 gccgtcatct gtccgtacat cattaaccct tttttctcaa gttcgtggaa atgctcccag
    13561 tctgcccact tcggaacaag aacagaattt gctaggagca cgcgcggggc ctgcgggtgt
    13621 gtacggaaca tgccaacggg ttttccggat tgcacgagca atgtttcatc attttttaat
    13681 gttttcaagg aatgctcaat ggcgtgaaaa gcgtcccaat cccgtgcggc tttgccaatc
    13741 ccgccatata cgatgaggtc ttccggcttc tcggcgactt ctggatcaag gttgtttcga
    13801 agcatccgaa gcactgcctc ttgctcccat cctaagcatt caagctctgt tcctctgttg
    13861 gcacggattg atttttttac atcagtcata tgttcatccc ccttagttct ttattctgat
    13921 gatcaggtat taaagattct ttcttcagcc agtcagtcaa gcgttcaatg tcataggaaa
    13981 aaacacggtc ctgctgaatg gacggcacga cttttctcat ttcctgaaaa agctgtttcg
    14041 tataggacgc tgcatgttct atgcctctgt attcaaccgc ctgcaatgcg caaatggctt
    14101 cgattgcaat gactctcctt gtatttgcga tcacctgata agcatgccga gcggcgatgg
    14161 ttcccatgct gacatggtcc tcttggttgg cggatgacgg aatagaatcc acacttgctg
    14221 ggtgggccaa tgttttattt tcagaaacga gtgaggccgc ggcatactgc atgatcatcg
    14281 caccggattg cagaccggga tgagggctca ggaacggcgg caggtcattc agctgcggat
    14341 tcacaagtcg ttcgatcctg cgctctgcga tattcgcaag ctctgatatt gcgattttta
    14401 gaaaatccat ggcaaaggcg atcggctgtc cgtgaaagtt tccgccagaa atcactttgt
    14461 caccgtcatt gaaaataaga ggattgtccg tagcggcatt catttcaatc tctaattttt
    14521 ctttgacata gcctaacgtc tgccaagtcg caccgtgtac ttgcggaata cagcgcaatg
    14581 aataggcatc ctggacccgc agttctccct gagaggttgt caggccgctg tcagatagat
    14641 agaagcgaat tcgttctgcg acatcgatct gctcctgata gccgcgggct aagtgaatat
    14701 cctcatcaaa cgcatctata attccccgca gcccttcaat cgttaagctg gcaatgcgct
    14761 cagtttgata ggctagtttt tcagcttcaa tgtatgagac cactcccatt gcagtcatgg
    14821 cctgagtccc gttaatcaag gcaagccctt ccttggatgt cagcgttacc ggttgaatac
    14881 ctgctttttt caagcctgtc attgccggca ttctttcccc ctcaaaaaag acttctcctt
    14941 gtccgatcag cgcaagcgcc aggtgggaaa gcggcgccag atctccgctt gcgccaagtg
    15001 atccctgctg ggggatgaca ggatggacgc gtttatttaa aaaagcaagc aactgttcga
    15061 tcagctcagc gcgtacaccg gaaaagcctt ttaacagcgc attggcgcgc aaaagcagca
    15121 ttgccctgga aacacactca ggaaaagggt cgccgactcc gcaggcatga gaaaggatta
    15181 aatttagctg cagcgccgcc gagtcttctt tctgaatcag gacatcgctg aatttgccaa
    15241 atccggtgtt gatgccgtag attgtctttt cgtcgcgtac aatccgttcc actgccgctc
    15301 tgcttttttt cacgcgctcc atactttcct cggaagccgc tgcctcctca aaatcaaaca
    15361 gcacacgagc gacgtcggct gttgtcaatg aagaaccgtc taaagtcacc ataagcccaa
    15421 ctcctttttc tttactttag taaagcgccc atacaaaaag gagctatgct gtgaacatct
    15481 gttttcacgc atagccccct atcgtctaag atctatgggc tgtttcatat gtgattaatt
    15541 ccaacaccga atgtctcgtg ctcaagacct ttaatcggcg ccccgattgt tccgtaaagc
    15601 gagacagcaa tccaatcgcc ttccgcttca ctttcataag gatttcccct caaaacggca
    15661 aacctcaagc ccaccgtccg aagcagcgat cccagcagca tttcacctct ggtcacgcca
    15721 tgcaaagcct ccatcgtcgc atgataaagc gcatgtgact cccgataacc ctcagattga
    15781 atgacaccgc tctttttgga agcggtttca attgcggcta ctactttatg cgcgtccatt
    15841 gatcctacct tgccaagaca gaccttccat ccgtctcgct ccagctcctc aacctgcgta
    15901 ctctcttccg cctcattcag cagcaggaga acagacagcc gtccgatccg acgctcttta
    15961 tgcagtgtca tatgaatcac tcaattccta aaaattctga taactattaa ctgagtatta
    16021 tattaattgg ttcagcagca gaagtcaaaa gattttttac agtctttaac aagttagatt
    16081 gctattgtaa tagcgcgacg cagagagcag aacaggtttt ttcagcgatt gcacacgata
    16141 tccagacaag gaggcaagcg ccgctgtctt actctcaata tgtgtttact aagtcgtatt
    16201 tttcgcaagg cattttctaa agagccagcc gaaaatcagg catcatctta aaaaacgccg
    16261 acaacgaaat ggctgtatca cagtcgatgc aaaacctgac aaagcagtta ttacatgtac
    16321 gcgaatgaaa aacagacgtg atgcaagaag gagaaacagc aaaagagttg aactatgaag
    16381 gagaggatat gcaagcagca gttctgtgcc aaacagacat cagtctgaca atgtaagaga
    16441 acagtgagaa atcacctatc tatatgaata tgaaaacatt cggctgtttt aataggccgg
    16501 tgtttcttca tagagaaatg taagcgctta aaaatttaat aaaaaagtga ggcgaattgt
    16561 ttagatgttc aaccgattgt tccgtgtatg ttttctggca gcccttatca tggccttcac
    16621 cctgccaaac tccgtctatg cgcaaaaagc aggaaaacca gtatttacag aagtcagcgt
    16681 ccatgaccct tccatcattg agacaaacgg caccttatat gtttttggat ctcatctcgc
    16741 ttcagctaaa acgaatgacc tcatgcaatg gcagcagctg accaccagcg tcagcaacga
    16801 caacccactt attccaaatg tctatgaaga attaaaagat accttcgaat gggcgcaatc
    16861 caataccctt tgggctgctg atgtcacgca gctggcggac ggcaaatact acatgtacta
    16921 caacgcctgc cgcggcgact cgcctaggtc cgccatgggt gttgccgtcg ctgacaacat
    16981 cgaagggcca tacaaaaaca aaggcatctt tttgaaatca ggaatggaag gcacaagcag
    17041 cgatggaaca ccgtatgacg caaccaaaca tccgaatgtc gtcgacccgc ataccttctt
    17101 tgataaagac ggaaagctgt ggatggtgta cggatcatac tcaggcggca ttttcatact
    17161 tgaaatgaat ccaaaaacgg gcttcccgct tcctgggcag ggatacggga aaaaactgct
    17221 cggtggcaac cacagcagaa tcgaaggccc gtatgttctc tacaatccag acacccaata
    17281 ctactactta tacctatcat atggcggtct tgatgcaaca ggcggctata acatccgtgt
    17341 ggcccgctcc aagaaaccag acggccctta ctatgatgca gaaggcaatc caatgctcga
    17401 tgtccgcggc aaagaaggca cattcttcga cgaccgttcc atcgaaccat acggcgtcaa
    17461 actcatgggc agctacactt ttgaaacaga aaatgaaaaa ggcaccgggt acgtctcacc
    17521 aggccacaac tccgcatact atgaccagaa aaccgggcgt tcctatttaa tcttccacac
    17581 ccgcttcccg ggcaggggtg aggaacacga agtcagagtc caccaattgt tcatgaacaa
    17641 agacggctgg ccggtagcag cgccctatcg ttatgcgggc gaaacattga aagaagtaaa
    17701 acaaaaagac atcacaggaa catacaaact tatccagcat ggaaaagaca tctcagccga
    17761 catcaaaaaa accatcaaca tccagctcaa caaagaccac accatttccg gggaaatgac
    17821 cggaacatgg aagaaaaccg gaaaaaatac agccgacatc acgttagcgg gcaagaagta
    17881 taacggggta tttttacgcc agtgggattc ggtgagagag aagaacgtca tgacgtttag
    17941 tgtgctgaat ggcagcggtg aggctgtatg gggatctaaa taagatggag aagcgccttc
    18001 tagagaaggc gcttttttat gagctttatt gactataaga aatggttgag cgagagaaaa
    18061 aacagaagtg atagcggggt tcaagaccta aacgaaaagt ccccatcatg atgattctcc
    18121 ctcttacaaa gttatgaaat tgaattttta gctatttaga accgggataa agttcctcaa
    18181 gacaatcctc tttacctatt tatccaatat gacccatcat gtaatatgaa aatagtctgt
    18241 attgtcaaga attgacacag tttgatagaa acacgaggtg ttgcggcatg catagtgaaa
    18301 tgttgttaca ttcggtaaaa gccgacttac atgaaaaaca ggaacaaatc catcagttaa
    18361 aacgagtgct gcacgaaatc aggcaaatca aacacgaatt ctccgaggcc cagcatctca
    18421 ttcaccggcc tcatcttaac cgggaggcat ggagaggaac acatgctgag cggtttgaag
    18481 atattcgtga aggaatgaac aaagcatatc agcaaattaa aagcgaacag gtcagtggaa
    18541 tcatcgagag catagaagga aaaatccatt cattagaggg cgatgtgtat tctataagac
    18601 gccaaatcac gaggatagag catgaaatag agaaggaaaa acataaaaag tgaggtgagc
    18661 acaaatggca caggaaatta aaatggtgta tggcacagtg aagcaagggc tttctcagct
    18721 caagaattca gctgaactca agtcctcctt acccggccat ctctcaggca gaaaccattt
    18781 gaatgttgta aagtccatcg agcaattaaa taaggacatc aaagagctca ctgaagcata
    18841 tgcgtctgtt ctggccaagc atatcgcaca aacggaaagc gcggtaaacg ccatgaagga
    18901 aacggacgaa aacatatcat cttccatgaa ataaagcgcg ggaggacaag ggattgaaaa
    18961 cattagatgt ccacgctctt cacgagggca ttcagcatac gattgagaaa ctggacaagc
    19021 aaaaacaaca gctggagaag ctggaaaaaa gcgttgagca tctggcaggc atgaaggatg
    19081 cgctgaaagg aaaaggcgga gatgccatcc ggacctttta cgaggagtgc cacaagcctt
    19141 ttctcctttt ctttggcatg tttatcggcg aatacaaaaa agtgctgaaa caaacacagc
    19201 atgcgatttc ctctgtagaa tctgactctc acggcatgat tgcagaggct tttctctcac
    19261 acgatgcgag acatggggtc aagcatgcac gagaagtgac agagcagctc actgatgcag
    19321 tcaatcgcca gacatcagcc atagatcaca tcgtcagcct gccggcagtc aatgatacct
    19381 ttttccgaat ggaaacagaa caggctgagc ggctgatttc ggacaccctg aataagctct
    19441 ttcaatttga cggccagcaa acccaagcac tagaaaccgc aaaatcagat tttcaaacga
    19501 tgaaaaaata tatagaccag ctcgaaacca tgtacaccgg cccgaaaatt gaaattacag
    19561 gctataaaag cggctccatc ttgaaatcgc aggaagaaga aaacatcaac caaaccttcg
    19621 gcgcgattaa cccgcaaatg aagcaggcgg atgattcacc gatggagatg atgctgaaga
    19681 aactagccga gaatgaaaag tctaaagtgg attcggttgt caaaacgggt cattctaaaa
    19741 aggtaagtaa aaatatcatc gttatcaatg gtaaagtgta taatacgagt gaacatagag
    19801 aacatataaa aactgatttc tcaaatgcag aggttaagca agtcgtttat aatgatacac
    19861 tttacaatgt atacatatct ggtaatgaca tgaagcttga acctgtcgtc tcgctttcgg
    19921 acattaaagt ggatgagaat ggatatgtga aaattttaga gacagctgta gagttttcag
    19981 gtataaatga tctgtttaga gctgctacag gcagagatcc tataacaggc gaaaaagtct
    20041 cgagtaaaga tcggattgtt gcaactgttc acgcggtacc aatttcgaaa atagctaagt
    20101 tgcaaaaatt taatatatat aagttaatta atggtgagat aaagacgaag aaggcttcta
    20161 agattgaaaa aggtacaaag aaaaataaaa atgacaaggt actaactaaa aatggagcct
    20221 ttagagatgc caaaaggaga gcaggaatac ctaactcttc tcaacataag aagccagtag
    20281 acgtttttga tggaacaagt gagaatagaa gggtatatga atttgaagta gatggtaaga
    20341 aaaaatatat tatagagcat agagaagaca aacttggtcg ggggccccac tttcacggtg
    20401 ctgatgattt aaaaggtaat ccgctagaaa aaggaagata taatcagtat cctggtcact
    20461 caccagagga ttttgaaggt tataaaaata aaggaaagtt taagaaaaaa ggtgattaaa
    20521 acttgaataa cgagagagtt aaaaagatgg aacttctaaa aaggaaaagt agaagaaaaa
    20581 atttaattag agaattagat ttcttacata taactgagga ttccttttta gatattgaag
    20641 aaaacgagct gttctgcaaa aaagcatttt caattcttga cacaaagcag aataaagtac
    20701 aaatacaagg tactgattat atagagaata ttcaaaaatc tattcaatta ttaaaggata
    20761 cttttgagaa tgtggaattg ggttcaaatg aagcaaggct actttttttt agggaaaacg
    20821 aaatagaggc tgttttatta tctttagacg aaatatttat aaatttggac aaagtgctcg
    20881 aaatcacaaa attttcaatt ggatatggag attttattct tacatcagaa gatttcaaat
    20941 tcggattatg tatagaacgg acagaatatc actatgaatt ttgtgtctgg ggattatcta
    21001 aaaaaaataa aaaataaagg tttttatata ttgaacaaca gttgaagaaa tgtcttttta
    21061 tttatgttaa tgatagagag tgcagaatat gggtaatgaa tttttattaa gataaataaa
    21121 tgaatcatta atttttatta agataaataa atgaatcatt attgaaatca acatattaga
    21181 agaggaatta aaataaagaa aaaccttgaa gggagcacct ttcaaggttt ttgacaatta
    21241 tcatcttttt ctagcgacaa taaaaagtaa ggggcggtta gtaattttta ccttttataa
    21301 tgaatatgat ttattagaac tgtttgatag tgagccaata agcgtggtga gtgatcccct
    21361 tgcagaaata ttcatatact ctatccaaga tatgaaaggc tttaaactga ttctgacaat
    21421 ggatgtatac gctttggagt gcaatctaag tctcaccttc aatgagttgc ttgtttttga
    21481 atctaagttt ataaatgtta ctcaattaaa gagatgtaat tctgatctat ttatatatat
    21541 tcataacgaa ccaaaggtaa aggttatatt taaaaagcaa cttggaatta tttttgttta
    21601 atgacatata tgaaagcaag gatgttagaa attaaaaatc gctttaaata ctttcaaagt
    21661 acatcatgta aatgacgatt ggaaaactct ttacgttggg ttgaagcaag ggtggataaa
    21721 caaaattgaa gtaatgaatt atgctgttga atatttgatg aaccatcccg gtgtataaca
    21781 agaagaaatt ctagaactgg cttggggaga caaggatgat attgaagaag ccattttgaa
    21841 tatattacga gttgaagaaa atagtttcta tgctattgaa aaaagaaaat ggagatatgt
    21901 tattcttctt gaagtaaaat caaagtatag tgatcatgga attgaacttt tgagcaagct
    21961 tgcggaagtt tatgcagata tgaattaccc tgaagatatg gcgggtttta ttcattatca
    22021 tccttttaat aacgggtgta actcgcattt acattcctat gaaaaaaata taaatagatt
    22081 atgcaatttc aagatttttt agtaaggaaa aaacaaaata tacaaaatgg cttaccgtta
    22141 taaaaaatag tccttattga gcaatcacct tagtcaacac caaaaatgaa agcgttgaca
    22201 tcccgcaagt ctagtgctaa agtataccta caaacaaata aaacgacccg tcaggattgt
    22261 tactgcgaaa gcaggcaaaa cctaaatggt gcaggtgcag gaggagactc tcgcaatctg
    22321 tgtcatttag gtttttttta ttctctttta ggaggtgatg cagcatttga tagaaaaaaa
    22381 gctggtgaaa ggcggccacc tttcttccag cagtcccccc ataaaaagga ggtatataca
    22441 tggattatga taaattatcg aaggacatat tacaactcgt aggcggtgaa gacaacgttc
    22501 agcgcgtgat tcactgcatg acgaggctgc gttttaatct tcatgacaat tcgaaggcgg
    22561 atcgcagtca gttggagcag ctgcctggag tgatgggcac caatatcagc ggcgagcagt
    22621 ttcaaatcat tatcggaaac gatgtgccga aggtgtatca ggcgattgtg cggcacagca
    22681 atctcagtga tgaaaagagc gctggttcat cctctcagaa aaagaatgtg ctgagtgcgg
    22741 tctttgatgt gatttctggt gtgtttaccc cgattctgcc tgcgattgcg ggagcgggga
    22801 tgatcaaagg gcttgttgcg ttggcagtta cgtttggctg gatggcggag aagagccagg
    22861 ttcatgtcat tttgacggct gtcggtgacg gcgcgttcta cttcctgccg ctcctgctag
    22921 cgatgagtgc ggcgagaaaa ttcggaagca atccgtacgt agcggctgcc attgcggcgg
    22981 cgatcctgca tccggatttg acagccctgc tcggtgcggg gaaaccgatt tcctttattg
    23041 ggcttcctgt aaccgctgcc acttattcgt caacggtcat cccgattttg ctggcgattt
    23101 ggattgcttc atacgtggaa aaatggattg accgttttac acacgcatct ctcaaattga
    23161 ttgtggttcc gacattcacg ctattgattg tcgtgccgct gacattgatt acagtcggtc
    23221 cgcttggcgc tattttagga gaatacttgt cttctggggt caattatttg tttgatcatg
    23281 cagggcttgt ggcgatgatt ttgctggctg gtacattctc tttaatcatt atgacgggca
    23341 tgcactatgc ctttgtgccg atcatgatca acaacatcgc tcaaaacggc cacgattatt
    23401 tactgccggc tatgtttttg gcgaatatgg ggcaggcggg agcatcattt gccgtcttcc
    23461 ttcgctccag aaacaaaaaa tttaaatcac tcgcgcttac cacaagcatc acggcgctga
    23521 tggggattac agaacctgcg atgtacggcg tgaatatgcg attgaaaaag ccgtttgcgg
    23581 ccgctttgat tggcggtgca gccggtggcg cgttttacgg catgacgggt gttgcttcct
    23641 atatcgtcgg aggtaatgca ggtctcccga gcatccctgt ctttatcggc ccaacgttta
    23701 tttacgcgat gatcggcctt gtgattgcgt ttgcggcggg aacagcagct gcgtatttgc
    23761 ttggattcga ggatgtgcct tctgacggca gccagcagcc ggcagtgcat gaaggcagca
    23821 gagagatcat tcacagcccg attaagggag aagtgaaagc attaagtgaa gtcaaagacg
    23881 gagtgttttc tgccgggatc atgggaaaag gattcgccat tgagcctgaa gaaggagaag
    23941 ttgtgtcgcc tgttcgtgga agcgttacca ccatttttaa aacaaaacac gcaattggca
    24001 ttacgagtga tcagggagct gaaatactca tacacattgg attggacacg gtgaagctgg
    24061 agggacaatg gttcacggct cacgtcaaag aaggcgacaa ggtcgcaccg ggagatccgc
    24121 tcgtgtcctt tgatctggag caaatcaaag ccgcgggata tgacgtcatt accccggtga
    24181 tcgtgaccaa cacagaccaa tattcatttt cgccggtaaa agagatcggt aaagtgcaga
    24241 caaaagaagc gctgcttgct ttatcttgaa aaaactaatg gggtgatcaa tatgagttca
    24301 aacgcaaaac gatttccaga aggattttta tggggcggcg cagttgctgc caaccaagtg
    24361 gagggtgctt ataacgaggg tggtaagggg ctttcgacag ctgacgtatc gccgaacggg
    24421 atcatgtctc catttgatga atcaatgact tccttgaatc tgtatcacaa cgggattgac
    24481 ttttatcatc gttataaaga ggatatcgcc ttatttgcag aaatgggatt taaggcgttc
    24541 cgcacatcga ttgcgtggac gagaattttt ccgaatggcg atgaagagga gcccaatgaa
    24601 gaaggcctca gcttttatga tgatctgttt gatgagctgt taaggcatca tattgagcct
    24661 gtcgtaacca tctctcatta tgaaatgccg ctcggtttag tgaaaaatta tggaggctgg
    24721 aagaatcgca aagtcataga gttttatgaa cgctatgcca aaacggtttt caaacgctat
    24781 caacacaaag tgaagtattg gatgacgttc aatgaaatta acgtggtgct ccatgcgcca
    24841 tttaccggag gcggccttgt ttttgaagaa ggagaaaaca aattaaacgc gatgtaccag
    24901 gcggcacacc accaatttgt ggccagtgct cttgctgtca aagcgggcca cgacatcatt
    24961 cctgattcga aaatcggctg tatgatagcg gcaacgacaa cctatccgat gacttctaag
    25021 ccggaggatg tcttcgcggc aatggagaat gagcgcaaaa cacttttctt ctcagatgtt
    25081 caggcaagag gcgcataccc gggatatatg aaacgctatc tggcagaaaa caatattgaa
    25141 attgaaatgg ctgaaggcga tgaagagctc ttgaaagaac atacggtgga ttatattgga
    25201 ttcagctact acatgtcgat ggcggcgagc acagatccgg aagagcttgc aaagtcaggg
    25261 ggcaacctgc tgggcggagt caaaaaccct tacctcaaat catcagaatg gggctggcaa
    25321 attgatccga aaggcttgcg catcacgctc aacaccttat acgaccgtta tcagaagccg
    25381 ctgttcattg ttgaaaatgg ccttggcgct gt
//
