LOCUS       c00061_JADNKT0..        5834 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JADNKT010000073.1 Lacticaseibacillus paracasei strain
            1001095A_150126_G7 NODE_307_length_32117_cov_23.7909, whole genome
            shotgun sequence.
ACCESSION   JADNKT010000073
VERSION     JADNKT010000073
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-19 22:02:29
            Original ID  :: JADNKT010000073.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5834
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5834
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[388:834]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      389..834
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..5834
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5834
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(2..253)
                     /locus_tag="ctg61_1"
                     /transl_table=11
                     /translation="MDKIISIIIVILILLATIAFYLAPFVGGLWQGAARSKVIAKILLL
                     NRDLKLSSKGLSRLINPQNPYIVAGESSITASFIGIKE"
     CDS             complement(389..604)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_2"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.9e-09,
                     bitscore: 29.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISKEVGITLKQHDLVLIQGGAKRRNKPSGCIVSTIGGAVAGAAG
                     LNPFTTVAGAAIGLSLCLSTNYIHPA"
     CDS             complement(601..834)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_3"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 4.3e-15,
                     bitscore: 47.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYNYRQLDDFQLSGVSGGKKKFDCAATFVTGITAGIGSGTITGL
                     AGGPFGIIGGAVVGGNLGAVGSAIKCLGDGMQ"
     CDS             complement(1106..2059)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     223.7; E-value: 5.1e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg61_4"
                     /transl_table=11
                     /translation="MKQVRLGGSNWQASSVALGIMRMNVLAPDKAANVLDSAYNDGINF
                     IDSADIYGQGKSEEVFGEALKQASVSRDQLFIQSKVGIVVDPKRSHGSLVFGKRYDFSK
                     DHLLSAVDHILKRLQVDYLDSVLLHRPDPLMEVDDVAAAFDALEQSGKVRHFGVSNFNP
                     EQIALLESGIRQPLLIDQVQFSVAHTGMVNAGMHTNMADAASVDHDGSLLPYLQRKHMT
                     LQAWSPFQYGMFEGTFIDSPKFKALNDELQKVADHYHTNKNAIAVAWLLRHPVGVQVIL
                     GSMNPEHIKESAEGADITLTRQEWYDIYFAAGNDLP"
     CDS             2264..2998
                     /NRPS_PKS="Domain: PKS_KR (6-169). E-value: 3.6e-12. Score:
                     38.3. Matches aSDomain: nrpspksdomains_ctg61_5_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     192.9; E-value: 1.1e-58)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg61_5"
                     /sec_met_domain="adh_short (E-value: 9e-35, bitscore:
                     111.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LTVKDKVVVITGASSGIGAATVQVLAEAGAKLVIGARRTERLAEL
                     AASFTDGQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEW
                     ERMIDVNIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIM
                     DGLRQEQAANHIKTTMISPGAVNTELFSTITDPKRREAVEADEKNNGLSASDVAKAVLY
                     AIDQPANVAINEVLLRPVTQER"
     aSDomain        2282..2770
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg61_5_PKS_KR.1"
                     /evalue="3.60E-12"
                     /label="ctg61_5_PKS_KR.1"
                     /locus_tag="ctg61_5"
                     /protein_end="169"
                     /protein_start="6"
                     /score="38.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVITGASSGIGAATVQVLAEAGAKLVIGARRTERLAELAASFTD
                     GQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEWERMIDV
                     NIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIMDGLRQE
                     "
     aSModule        2282..2770
                     /domains="nrpspksdomains_ctg61_5_PKS_KR.1"
                     /incomplete
                     /locus_tags="ctg61_5"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       2285..2365
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg61_5_0001"
                     /evalue="1.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg61_5"
                     /protein_end="34"
                     /protein_start="7"
                     /score="14.1"
                     /tool="antismash"
                     /translation="VVITGASSGIGAATVQVLAEAGAKLVI"
     CDS             3024..4187
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217:NADH:flavin oxidoreductase/NADH oxidase (Score:
                     289.8; E-value: 4.6e-88)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg61_6"
                     /transl_table=11
                     /translation="MSGYHFLKPFTFKHQTITLKNRIVIPPMTTRLSFEDGTVTRDEIR
                     YYQQRAGGVGMFITGTANVNALGKGFEGELSVADDRFIPGLSKLAAAMKTGGTKAILQI
                     FSAGRMSNSKILRGEQPVSASAVAAPRAGYETPRALTPAEIEATIHDFGQAVRRAILAG
                     FDGIELHGANTYLIQQFYSPNSNRRTDEWGGDRDKRMRFPLAVVHEAEKMIATIADRPF
                     LLGYRISPEELEQPGITLDDTLALIAALKQTKIDYLHVSQSDVWRTSLRNPEDTAIMNE
                     QIRNHVAGAFPVIVVGGIKTPADAEKAAESFDLVAIGHEMIREPHWVQKVLDHDEKAIR
                     FQIAPADLEELGIAPTFLDFIESISGGAKGVPLTTAQSVTSSNVTQD"
     CDS             complement(4449..5825)
                     /locus_tag="ctg61_7"
                     /transl_table=11
                     /translation="MSKYRTETDTLGPVEIPANALWGPQTERSRHNFQAGPLMPMPVIR
                     ALLQLKKAAARANVAADVLPAPKGQLITRAVDALLALPDEKLQKDFPLHVYQTGSGTQT
                     NMNVNEVISHQAAKLNPDLPILPNDDVNHSQSSNDTFPTVMNITSAIAVNQLLHAVNQL
                     CSVLYSKAVTYARVVKIGRTHLQDATPLTFGQEISGWVAMMEHDQIALKQLQPNLFYLA
                     IGGTAVGTGLNADPNFGKIVAGRLSDVYQLPLSAKTNKFAALAAHSEISVVHGAIKTLA
                     ADLLKIANDIRFLASGPRAGYGELRIPANEPGSSIMPGKVNPTQAEALTMAAVRVMGND
                     TTITVAASQGNFELNVYKPVIISTFLESADLLTKTVTSFTEKLAAGLTIHAPHMRALVD
                     HSLMLVTALAPHIGYEKSAAIAQLAEQENLDLKAAAIKSGDVTAAQFDKWVDPLKMTRA
                     "
ORIGIN
        1 actattcttt gatgccaata aagcttgcag ttatgctgct ttcaccagcc actatataag
       61 ggttctgggg attgattaac ctactcagcc ccttactaga tagtttcaaa tctcgattta
      121 acaaaagtat cttggcaatg actttgcttc ttgctgcccc ttgccaaagt cctccaacaa
      181 atggtgctag ataaaaagcg atcgtcgcca gtaaaatcaa gataactatg atgatactta
      241 ttatcttatc catttgtatt tcctcttcct tttgtacaaa tagactaatt tgaaatcgat
      301 ctttgactaa gacaagaaaa agtgagcact accaaggtgt tagttatatt gaacagttgc
      361 gataggagct aaccgtcttt gtccaatatt aggctgggtg aatgtaatta gtgctgagac
      421 acaaggataa tcctattgca gcgcctgcaa cagttgtaaa tggatttaat ccagctgccc
      481 ctgctaccgc tcccccgatc gtggacacaa tacacccact aggtttattg cgtcgcttgg
      541 ctcctccttg gattaagacc aaatcatgct gttttaaagt aatgcccact tctttactta
      601 tcattgcatc ccatctccta agcatttaat agctgaccca accgctccta agtttccacc
      661 aactacggcg ccgccgatta tcccaaaagg accaccagct aggccagtaa tcgttcctga
      721 tccaatacct gccgtgatgc cagtaacaaa tgtagcagca caatcaaatt tctttttccc
      781 acctgaaacc cctgacaact gaaaatcgtc gagctggcga taattataag acataatttt
      841 ccttttttct tcaaaaggca acaagttatt ttgtgtaagg tcgactttac tgtctttaac
      901 atacattaat tatttgtgta aaatgccaaa attttttaaa cgtaggaaat ttccagttta
      961 acgtcgtctt tacactttta ttgttcagtt gcgctttaaa agtcaaaaat tcttaacgtt
     1021 taaatctcct tgcttggtaa aaacttcaat tttttgcaaa aaaaatcgtc tcagcaattt
     1081 gagacaattt tttcatatca tcaacttacg gcaaatcatt ccccgccgca aagtaaatgt
     1141 cataccattc ttgtcgggtc aacgtgatgt ccgcgccttc cgcactttcc ttgatatgtt
     1201 caggattcat agagccgaga atcacctgca caccaactgg atggcgtaat agccaagcga
     1261 ctgcgattgc atttttattg gtgtggtagt ggtcagcgac tttctgcagt tcatcattca
     1321 acgccttaaa cttcgggcta tcgataaagg tgccttcaaa catgccgtat tggaatggtg
     1381 accatgcttg taaggtcatg tgtttgcgtt gtaagtatgg taataggctg ccatcatgat
     1441 cgaccgaggc agcgtcggcc atgttggtgt gcatccccgc attgaccatg ccagtatggg
     1501 caacggagaa ttgaacttgg tcaatcagca aaggctgccg aatgccgctt tcaagcaacg
     1561 caatttgttc agggttaaag ttggagacgc caaaatgccg aaccttgcca ctttgttcca
     1621 atgcatcaaa ggccgccgca acgtcatcga cttccattaa cggatctggc cgatgcagca
     1681 agaccgaatc aaggtaatca acctgcaacc gtttcaaaat gtgatcaacc gctgacagta
     1741 agtgatcttt tgaaaagtcg taccgtttgc cgaataccaa actgccatga gagcgttttg
     1801 gatcaacgac gatcccgact ttcgattgaa tgaataactg atcgcgggaa acgctggctt
     1861 gcttcaaggc ttcaccaaaa acttcttcgg atttgccttg gccataaatg tcggccgagt
     1921 cgataaagtt gatgccgtca ttgtacgcac tatccagcac attggccgct ttgtcggggg
     1981 ccagcacatt catccgcatg atgcccaagg ccacacttga cgcctgccaa ttggatccgc
     2041 ctaatcgaac ttgtttcata aacacaaaac tcccttcgat acgtcatttc aaattatgtt
     2101 actgacgaca agttaagtgt agcccctaaa gtccacttga ggtcaagcca atattagaat
     2161 ttcaataaaa cagcttgcat ggtgctgagc tgcgcggtag gttaaactgt gtttgttact
     2221 tattttttct tagcaggata agcccataaa ggaggccgtg attttgacag ttaaagataa
     2281 agtggttgta atcacaggtg catcgagcgg gattggcgcg gcaacggtac aagtgttggc
     2341 cgaggctggt gcaaaactag tcatcggtgc gcggcgcaca gaacggttgg ctgaattggc
     2401 ggccagcttt acggacggtc aggtgctgta tcaacaaacc gatgtgaccg accagcagca
     2461 agtgaaagcg ctgattgatt tggcgttgga taagtttggt catgtggatg ttttgtataa
     2521 caacgctggc ctgatgccac tttctgaaat ggccgaactc aaagtcaacg aatgggagcg
     2581 gatgattgac gtcaacatta aaggcgtctt gtatgggatc gccgcggttt taccgcctat
     2641 gattgcccaa cacagtggcc aaattatcac aacagactcg gtcgccggtc acattgttca
     2701 ccctggaacc gccgtttact ctggtaccaa gtgggctatc caggcgatca tggacggcct
     2761 gcgacaagaa caagcggcta atcatattaa aacgaccatg atctcgcccg gtgccgtgaa
     2821 tactgagctt ttcagcacaa ttaccgatcc taagcgccgt gaagctgttg aagccgatga
     2881 aaaaaacaat ggcctcagcg cctcggatgt tgccaaggca gttttgtatg ccattgatca
     2941 accggccaat gttgccatca atgaagtgct cttacggcca gtcacgcaag aacgttaatt
     3001 ttcgtctaaa ggagtgtgat tgcatgtcgg gttatcattt tttaaaaccg ttcaccttca
     3061 agcaccaaac catcacgttg aaaaatcgca ttgtcattcc gccgatgaca acgcgcctgt
     3121 cgtttgaaga cggcactgtg acgcgggacg aaatcaggta ttaccagcaa cgggccggtg
     3181 gcgtcggcat gtttattacc ggtaccgcca atgtcaatgc gcttggcaaa ggattcgaag
     3241 gtgagctaag tgtcgctgat gatcgattca tccccggttt gagcaaactc gccgctgcga
     3301 tgaaaacagg cggcaccaag gctattttgc aaatcttcag cgctggccgc atgagcaata
     3361 gcaagattct gcgcggtgag cagccagtca gtgccagtgc ggttgctgcg ccacgggcgg
     3421 gttacgaaac accgcgcgca ttgacaccgg cagaaattga ggccactatt cacgattttg
     3481 gtcaggccgt gcgccgcgcc atccttgctg gttttgatgg catcgaactg catggtgcca
     3541 acacatatct gatacagcaa ttctattcgc caaactctaa tcgccgaacc gatgaatggg
     3601 gcggtgaccg cgataagcgg atgcgttttc cgttggcagt cgttcatgaa gcagaaaaaa
     3661 tgattgccac aattgctgac cggccatttt tgttaggcta ccgcatttcg ccggaagagt
     3721 tggaacagcc tggcattacc ttggatgata ccttggcctt aatcgccgct ttgaaacaaa
     3781 ccaagattga ttacctgcac gtctcccaaa gtgacgtttg gcgaacctca ttgcgcaacc
     3841 ccgaggacac agccatcatg aatgaacaaa ttcgtaacca cgtcgccggt gcttttccag
     3901 tgattgtggt cggtggcatt aaaacccccg ccgatgctga gaaagcggca gaatcctttg
     3961 atttggtcgc gattggtcac gaaatgattc gcgagccgca ctgggttcag aaggtcttag
     4021 accatgacga aaaggcgatc cgtttccaga tcgcccctgc tgatcttgaa gaacttggca
     4081 ttgcgccgac cttccttgat tttatcgaaa gtatttccgg tggggcaaaa ggtgtcccgt
     4141 taacaactgc gcagtctgtg acatcaagca acgtgactca agattaatct agcatttcaa
     4201 atcatcgtgc gagtcgagct gtaaaaagct cgcctttttt cttgccgtct tcaacttacg
     4261 cgatggtgcc tgaagctacc agtgatttat aagttttaaa tcaaggtgtg atcatcacct
     4321 gctcacgctc tgatttaaac gcgttcacca gcgcagctcg gctatgcgaa gaacagtgac
     4381 acagatggtc caaagcccag accatctgtg tcactgccac ttcgctacgc cgagctaacc
     4441 gcgccagttc acgctcttgt catttttaac gggtcgaccc atttatcaaa ctgcgctgct
     4501 gtgacgtcgc cgcttttgat ggcggctgct tttagatcga ggttttcttg ctcagccaat
     4561 tgcgcgatgg cggcactttt ttcgtagccg atgtggggtg cgagggcggt gaccagcatg
     4621 agcgaatgat caacgagtgc tctcatatgc ggtgcgtgga tggtcaagcc ggcagctaat
     4681 ttttcagtga aactcgtgac tgttttggtt agtagatcag ctgactctaa aaaggtactg
     4741 atgataaccg gcttgtagac gttcaattca aaattgcctt gtgaagcggc caccgtgatc
     4801 gtcgtatcgt tgcccatgac tcgaacagcg gccatggtta gcgcttcggc ctgtgtggga
     4861 ttcactttgc ccggcatgat ggaactacca ggctcattgg ccggaatgcg caactcgccg
     4921 tatccagcac gtggaccact ggcaaggaag cgaatgtcat tggcgatttt aagcagatca
     4981 gccgctagcg ttttaatggc accatgaaca acgctaattt ctgagtgagc cgctaaagca
     5041 gcaaacttat tggttttcgc cgaaagtggt aattgataaa catcgctcaa tcggcccgcc
     5101 acaatcttgc caaagttagg gtcagcgtta agccccgttc cgactgctgt tccgccaatg
     5161 gctaagtaaa aaagattggg ctgaagctgc tttaaagcaa tctgatcatg ttccatcatg
     5221 gccacccatc cgctgatttc ttggccaaac gttagcggcg ttgcatcctg taaatgagtt
     5281 cgaccgattt taacaacacg agcgtaagtg acggcttttg aatataaaac actgcacagt
     5341 tggttgacag cgtgcagcaa ctgattcact gcaatagccg acgtaatatt catcacagtt
     5401 ggaaaagtat cattggagct ttgactgtga ttcacatcat cattcggtaa gatcggcaag
     5461 tcggggttga gttttgcagc ttggtggcta atgacttcgt tcacattcat atttgtttgt
     5521 gtgccagacc cggtttgata gacatgcagt ggaaaatctt tttgcagttt ttcgtctggc
     5581 aaggccaaca aggcatcgac tgctcgcgtg attaattggc cttttggtgc cggtaaaaca
     5641 tcagcggcca catttgctcg cgctgccgct tttttgagtt gcagcaaggc cctaatcact
     5701 ggcatcggca tcaatggacc agcctgaaaa ttatggcggc tgcgctctgt ttgcggtccc
     5761 cacaaagcgt ttgccggaat ttcaactggt cctaatgtgt ccgtttctgt tcgatatttg
     5821 ctcatgttta cctc
//
