LOCUS       c00035_JADOAW0..       23731 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JADOAW010000017.1 Lacticaseibacillus paracasei strain
            1001713B170131_170501_F11 NODE_17_length_52669_cov_65.2556, whole
            genome shotgun sequence.
ACCESSION   JADOAW010000017
VERSION     JADOAW010000017
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2022-06-21 01:27:15
            Original ID  :: JADOAW010000017.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 28938
            Orig. end    :: 52669
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23731
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[38938:51074]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..22136
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..23731
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23731
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(1897..2355)
                     /locus_tag="ctg35_32"
                     /transl_table=11
                     /translation="VANYIREIRSKVGHMPIFLNAVAGAVVNEQGQLLLQKRTDAGNWS
                     LPGGMMEYGETFVETLQREMEEDAGLLVEPVKALHTFDQGFTTYPNGDQAQIICRFYLV
                     KPVGGSLAEADPKETLALQYFDFDQLPPLFNQQSRDMISFVQAYLQAH"
     CDS             complement(2605..3294)
                     /locus_tag="ctg35_33"
                     /transl_table=11
                     /translation="MAKLVLIRHGQSEWNLSNQFTGWVDVDLSEKGVEEAKHAGQLVKQ
                     AGLEFDQAYTSVLTRAIKTLHYVLEESDQLWIPEMKTWRLNERHYGALQGLNKKETADK
                     YGADQVHIWRRSYDVLPPLLKATDEGSAAKDRRYADLDPRIIPGGENLKVTLERVIPFW
                     EDHIAPDLLAGKNVIIAAHGNSLRALTKYIENISDADIMNLEMATGEPVVYDFDEKLNV
                     NSKSKLD"
     CDS             3528..3734
                     /locus_tag="ctg35_34"
                     /transl_table=11
                     /translation="VKKIWLSIAGVWLISVIYFIVYLTVPAMQVAVNASGLLSLVHGVM
                     DLILLGGAFALIAGALYRIFHRR"
     CDS             3827..4897
                     /locus_tag="ctg35_35"
                     /transl_table=11
                     /translation="MFKICPNCGAHNTATAKFCTRCGTSLAGVVATAETAVQSAQPTSE
                     NEASTANTAAVSEQSSVPSSLTSSSAQNQPVTPQQAQSQVTPPDNSQQQVPPQPAGTQT
                     QSQQTAQGPAPTAQPYQQADQTQQQAQTPPEEPNPTVEATKKYAGSYWRYLVDSIKHPA
                     TVTRPYHQYFGLTSLAITIVSLALTIALMTGSAVSSLPGAIASNVLMTFLKLVFLVAVL
                     MIAVVAVYYLVVNGMLGDRRRSFLTFTTEYAFHCNWMVFFSVFTLLMQMLGMINIGSIF
                     LIWLLLSLGSGLFVISGTYMLFTAQSTNRFDKIYAYLIVGILLVIVFLIIMTFGLSSIL
                     GGIGQGINDFGRSFNF"
     CDS             complement(5004..6104)
                     /locus_tag="ctg35_36"
                     /transl_table=11
                     /translation="MTMHKHRWLIVIVLAVALVAATGLTMAWVYHQRQASKIVARPVPQ
                     AQVGKHAQALIKKTAFTGSVALIKNGQIVYTGGVGDADHGQHEANNGETMFPLASVEKY
                     LTALVIGHLIAEHKLSFNTKLAEFFPKIDHSKDISIRQLLDHRSGIQMDELTPDQTLTS
                     EQAILDWTFEQMGSTGDHSFIYANANYAVLAGIVRQVTGKSFANVLQQTIITPLQLTHT
                     HNFTALTAQMPVAQGYLTAGDNDYQPDELSNALLSTLLGSGSVYMSATDLAKVIIAAET
                     GKIMPLKVYHQLINANYGDGNPYASGVMWLDDQRLLQGMYNDNPESFSTLAYFRADAKS
                     GVVLFGNHTMSTDTVSLAQNLEALVN"
     CDS             complement(6091..7194)
                     /locus_tag="ctg35_37"
                     /transl_table=11
                     /translation="VYLVKNVGKSMSGYEKFINNLPVRRTVVLFSVFLLLWFARSIMSD
                     ILLTFIFAFLVSRLVHAVQRHVHIRPFVIVVPVYILVILGLVYAAVHYVPAIIHQTIGL
                     FNSVQNFYNSEAFANNQVMQWVLQSTKSLNLTEQLKTGVTTVLQYAGNIGAMGLTLFVS
                     FILSFFFTIELDSLPAFGQLFLDSPFGWYFKDLQYFAMKFINTFGVVMEAQIFIAVVNT
                     VITTITLLFLKMPNTPSLAIMVFLLSLIPVAGAIISLIPLTIIGYTVGGWQDVLTILIM
                     IAAIHVLEAYVLNPKFMSSRTQLPVFFTFVVLLVAERLFGTWGLIVGIPIFTFFLDVLG
                     VKKIAGTAHKQSTYASVPQPKEHDDDA"
     CDS             complement(7249..7950)
                     /locus_tag="ctg35_38"
                     /transl_table=11
                     /translation="MTQSNKKQPPRKHRWLWRTIFTLGILLGLALIFNEPIKLFVVDHL
                     SQWTMAQVDRDNVNKNEKRKATFDFKGVKALDINTVGNAALNRDLHPIGKVAIRSVGLK
                     LPIFKGLSNENLSAGAGTMKADQKMGEGNYALAGHYMTNQGILFSPLKNVKQDDIIYIT
                     DMKKVYSYKVTSKQVVNETQVQWIDDVAGKKLITMVTCASPTEGEVDRIIIQGQLQSVK
                     KATKQHLKVFL"
     CDS             8393..8803
                     /locus_tag="ctg35_39"
                     /transl_table=11
                     /translation="LKKLFQLYKRYEMIINYLFIGGLTTLINFVTFFAMRYFGIGLVLT
                     NTTANIVSVIFAFFANKSVVFHSDYSSKKKFWFELISFLVLRGVSLLLDNLIMIIGVDW
                     LHSNEILVKILDQVIIVIANYLFSKLIFLRKK"
     CDS             complement(8857..9789)
                     /locus_tag="ctg35_40"
                     /transl_table=11
                     /translation="MPFAEVIMNPSAGNARWKKQLPELVAIIESHFAPLHISQTRKAGD
                     ARLVTERLIKAYQHKMDDLQLIVIGGDGTLHDVVNGLQRQGHPEVAIGYVPTGTGDDFA
                     RANHIPLDPKKAAAALTTAMPHALKIGVADSAKYGTQYFINNFGIGMDAQIVYQTNHSD
                     HKAALNALKLGHFSYAASILKALRQQKKFRATWQVDGKTTAIDNAYLNVFTNHPFLGGG
                     LRLFPDKADNRNTLSFVQVHREKLGILLQVLFAILSGRSVHRAMHHSQGQTFEFATSAT
                     VPIQIDGEEYSTPIQVTLHQTKQLFLLPT"
     CDS             complement(10001..11761)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_41"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.9e-33, bitscore:
                     107.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKTIKAGVAALKTLESWGVTHVYGIPGGTFNNMMYALDEEKDNL
                     KYIHVRHEEVGALAAVADGKLTGHIGVAFGSAGPGATHLFQGAYDAKMDKVPTLFLVGQ
                     VEQRFMNYDFFQELDEDPMFQDAALYARTVTTAASLPHIIDEAIRRAYAGRGAAIVVIP
                     NDLAAEEIPADGYYSAAATHATPVLPAGSDEQVDAALRLIGAAQRPVMYVGQGVRGAAD
                     TVMTLARKLQMPVITTALGKPIIPYEFESLLGSAARVASKPANEALRVADLIMFVGSNY
                     PFAEVMFSPNAKFIQIEADSKTLGKRHHTDVAILADAPATLKKMIDRSDDAPRSGWYQA
                     NVDNVKNWHQYNDDMMTRTTGKMRFEPVFGQINRIATDDAIFAIDVGDVTQNAVRLLKV
                     NGRQAWTTSGLFATMGAGLPAALAGQLSFPKRQVFNLAGDGAAAMVMQDLDTEVRYHLP
                     IINVVFSNNALGYIEDEQEDDGHEWFGIDMPAIDFATVAKGMGMTGITVTQVDELPAAF
                     ETAEDNRAAGKPTLIDAKITNERPIPVEHLQLDPNQFDADTIAAFKKRYYAERLVPLSE
                     FLKTHKVPVA"
     CDS             complement(12325..13227)
                     /locus_tag="ctg35_42"
                     /transl_table=11
                     /translation="LTFLKKIAAALAVLITVGALAACSSTQPKYDAKEPLGPQINYTIT
                     GIDAGAGVMTSTDKALKAYGLVDKKWQLQPSSTAAMTSTLQKAIADKRPIVVTGWTPHW
                     MFTKFPLKFLKDPKNVYGKTEQIHTIVRKGLKQDAPQAYQVLDQFHWTPEEMSSVMLAV
                     NGGKDPAEAAKAFVKKHPEQIAQWTKGVTHVSGKPKLTMTYIAWDSEIASTNVVATVLR
                     QIGYNVTIRAMEPQPVWASVATKAADAQVSAWLPNTSAKLYSDYKNQVVDLGVNLDGAK
                     VGLAVPKYMKNINSIEDLK"
     CDS             complement(13239..14090)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 83.9; E-value: 3.9e-26)"
                     /gene_kind="transport"
                     /locus_tag="ctg35_43"
                     /sec_met_domain="BPD_transp_1 (E-value: 3.2e-26, bitscore:
                     83.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNILISIPTLPLAHWVDSFVAWLTQFSGFFGVLTNFIGGIVNAF
                     QAVFDFIPIWLFIILVLALTWYLKRDQKYRSLLIFELLGLLLIWNLGFWRDMTQTLTLV
                     LTASLLAIVIGVPLGIWAAESKSVSAVVKPLMDFMQTMPAFVYLIPAVAFFGIGMVPGV
                     VASVIFAMPPTVRMTQLGITQVPADLNEAAVAFGATGWQQLLKVQLPFARGTIMAGINQ
                     SMMLALSMVVIASMIGAMGLGTKVYFAVGRNDAGGGFVAGLAIVILAIILDRITQSLNR
                     SR"
     CDS             complement(14083..15306)
                     /locus_tag="ctg35_44"
                     /transl_table=11
                     /translation="MQHKVESNAETKIEVRGLTKIFGKRVNRAKEMLKAGKTKPEILKA
                     TGATVGVDRADFSIKTGEIFVIMGLSGSGKSTTLRMLNRLIEPTDGQVLIDGDDIAKLD
                     KQALREVRRQKLSMVFQGFALLPNRTVLQNAAFGLEIQGMEKDEREMKANKALDLVGLN
                     GFADQYPDQLSGGMQQRVGLARALASDAEILLMDEAFSALDPLNRRDMQDELLDLQEDM
                     QKTIVFISHDLNEALRIGDHIMIMKDGEIVQIGTPEEILSQPADDYVEKFIEGVDRSQV
                     YTAANVMIRANTVNIDRDGPRLAARRMRDNEISSLYVVDTKRKLVGILDADDVRSAIDA
                     GQKDLRSIVKSDVPTTKMDTPLADLLDAVSTTPVPFAVVDDHDRLRGIIIRGAVLGALS
                     GQEVNVNV"
     CDS             complement(15575..16306)
                     /locus_tag="ctg35_45"
                     /transl_table=11
                     /translation="MYYQNVSVGQLIKRVSRFTVEIDLNGTVEPVHMNNTGRNKEILIP
                     GSLASVRYVDNPNRKTHYDLLAVQRQGRWINIDSLAPNHVTKECLEAGTLKLPGLALPY
                     AIHPESTWRDSRLDFAGKAADGQSWFVETKGVTLANGTLAAFPDAPTTRAVKHVHTLTM
                     AQAEGYQAFLLFIVQLPDIRQMTIYRDRFPELVTAITTAKQNGVRVLAYDTMTGPDQIT
                     LGNEIPFDEHLPFSEINLNSL"
     CDS             complement(16413..16874)
                     /locus_tag="ctg35_46"
                     /transl_table=11
                     /translation="LVTEDDLTIESMHYNRLLLAVDDDDDDSSRKALNYACTVAKIYDI
                     PLGIVSVLETGDLNIFQSLTPDDVDAARETLAKDLYTYVEKATAFGVQNAQPIVAEGRP
                     AAAILDEVIPAFKPDLVIMGSHVRRGRLRLGHVASEVARDASVSVIIVR"
     CDS             complement(16923..18182)
                     /locus_tag="ctg35_47"
                     /transl_table=11
                     /translation="MKDAPSFTPILLGSDMNVYGMARSFHEMIGGAIDVYAREQLAPTR
                     FSRIVNVHLIEHFDSDPTFIENMRQVAKVHADAPGKLLLIACGDTYAQLVSKHKDELSQ
                     WFICPYVDYELLKRLNSKESFYQVCEEYHLPYPATKIVTKSMYESNATITAPFEFPVAL
                     KPTDSVEWLNIRFEGRKKAFTIHSQVELTNTIAKIYDNGYTSDLILQDFVPGDDSNMRT
                     LNCYVDQYHHVKMMCLGHPLLEDPTPSSIGNYVAIMPAFDQDLYDQIKKFLEAIKFTGF
                     ANFDMKYDHRDKTFKLFEINIRQGRSSFFVTLNGYNLASWPVRDYIVGDLKDAPTVYGN
                     DDHSKYKLWLGVPERVFKQYSADNEAKKEALQLLKEKRYGTTVFYKPDMTFKRWLLMKY
                     MFHNYVGRFKQYFAENKGDM"
     CDS             complement(18467..19348)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_48"
                     /sec_met_domain="GHMP_kinases_C (E-value: 4.3e-08,
                     bitscore: 25.3, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 5.8e-14,
                     bitscore: 43.9, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISVSVPATSANLAVGFDVLGLALDLKAHFTFEMSTQKLEIIGDD
                     PAFANSENLIYQAFSKFAEAIDQPVPNLRIVVDSAVPSARGLGSSAICVVGGIAAANAW
                     YQAGWDDTALLRFATEMEGHPDNAAPAIYGQLCATIMAQNEPVVRQYTVSSKLHFVTLI
                     PDYAVSTADARRILPRTMTYADATYQMGRCTLMTRALADGDMSLLRQVATDRMQEPYRA
                     ELIPDYSAAHQVVQTAGGVLLISGSGSTMLAITDSSAAAAQVQAQAQESWKKWQVQVVA
                     PSQQGVQVEQFE"
     CDS             complement(19314..20828)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: PALP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_49"
                     /sec_met_domain="PALP (E-value: 9.8e-16, bitscore: 49.6,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRYTSTRDHQVSKTSKEAIKQGISEEGGLFVLPHLADQTLNIHEL
                     LDLDYETIAQRVLMILLPDFNTDSLKKAIHFAYHQHFSDDRITPVRSVGDFHVLELFHG
                     PTSAFKDVGLQLLPRLMQLALDPDDRVMILAATSGDTGTAALQGFKDVAQTGITVFYPN
                     HGVSPIQERQMLTVGSDNTRVFPIAGNFDQAQSAVKTLFTDTSFAARLQAEQVTLSAAN
                     SINIGRLIPQVVYYFAAYSQLVKTQAISMGDEVNFTVPTGNFGDVLAGYYAKSLGLPVH
                     KLIAAANANSELADFLATGVYDRNRPFLKTVAPSMDIQISSNLERLLYYKSGEDSAYVA
                     HLMQELETTGRYQVRPDVLTAIQVDFAGGFAVDEEVADAIREVWHRDGYLLDPHTAVGY
                     AVQQQYRAASGDNTPNVLLATASPYKFPRVVAKALQSHVPDDDFAAMQMLQQVSGVTIP
                     PNLARLQQLRPQEKIVVAPTDMGQAIIGAAKEVFNDDQRVRSGNER"
     CDS             20937..22136
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: Homoserine_dh"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_50"
                     /sec_met_domain="Homoserine_dh (E-value: 2.9e-49, bitscore:
                     159.0, seeds: 932, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIAILGFGTVGSGVYDIIANGDTRMRVTAIFIRPTHPATMPEMT
                     TDLDAILNDPTIDVIVETMGGLHPAHDYILQALQHDKHVVTANKAVVAKYLPEFTAVAA
                     QHHVQFYFEATTGGGIPWIRNLERAARIDQIDTIEGIFNGTSNYILDQMQRAHLDFDPV
                     LLAAKDMGYAEADPSADIDGEDVVNKLKISAALAYNMAPPRDVPTFGIRNVSKADIDFF
                     ASQHQVLRLIGKSKRDGDHYSMVVEPRLYSETALAANTFENFNLIRLHGQTIGDLQFYG
                     QGAGKYPTANAIVQDLYDILENAPHLDRSFDQPLHFDANLNVTDYVLRADPMTFAMFND
                     RETEIVNDRLVIKQIPTGDMHKLMRGVLAIDADAFMAAIGDSELAAKDVLHQRDQEVIG
                     "
     CDS             22133..23479
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_51"
                     /sec_met_domain="AA_kinase (E-value: 2.7e-40, bitscore:
                     130.2, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVVKFGGSSVADAGQFQKVKAIIDQDVNRQIVVISAAGKYGNAT
                     RKLTDTLYLIADGMEAGRDVEPLFNQVLARLEAINIALQLNVPLIKLLHTIRHHLAIRY
                     SRDYLVSRGEFLTAHLMAAYLGYTFVDAANLLFFNKAGAIDEAKTQTAYQQLASHHGIV
                     VPGFYGRDADGHVKLMPRGGSDISGAWLARLAHADLYENWTDVSGIKMADPRIIKDADS
                     IDVMSYDELRELTYMGFSVFQEEAVQPVRECGIPTRILNTNAPEDPGTLIIHDDDPAND
                     LKTITGIAGRKHYLVITVRKYQLALHLEVIQHALGVVAAHHLVVDYLPTGIDSFSLLIR
                     EPRRQVSVQELTAEIAAACQPDKMEVTENVALIAMVSRKLRQRPAIAGKVLAYLDDNLL
                     NVQLVSQTNDDINLLIGVHDLDYDKAVRVIYSSIHQNFQRPAPYIEGIA"
ORIGIN
        1 tgcgacttga tcaggtcctc atgtgtgccg ctgccgctca ccgtgccatt ttcaatgaag
       61 tagatccgat tagcattcat gatcgtgctg agtcgatggg caatcacaat cgttgtacga
      121 ccatgcatta atttagttaa tgctttttga accatcattt ctgattcggc atcaagacta
      181 gcggttgctt catcgagcat taaaatcttg ggatcgcgaa gaaaggcgcg ggcaatggcg
      241 agtcgctgtc gctgaccgcc ggaaaccttg accccacgtt cgccgacttc agtatcgagt
      301 ccctgcggca tggcctcaac aaagattttt gcgtacgcca tatcaagcac atgccataat
      361 tcttcatctg tatagttgcg cgtcgcccca tacgtcaagt tataacgaat ggtacctgcc
      421 ataattgttg catcttgccc aaccagccca atctgctcac gcaaatcttc aacattcaga
      481 tttgcgatgt cctgatcccc gatcaaaatg tggccgctat caggcgagta gaagcgttct
      541 aaaagactga taatcgttga tttgccgcca ccagacggac cggcaaaggc aatgacctga
      601 ttaggtgccg ctgtcaccgt gacatctttt agcaccggcg tctcctgatc ataactaaaa
      661 ctgacatgcg acattgtcaa agcttgacca ctggcatctt ttagcgggcg acctgtgcga
      721 ctttcctcag gttgttgcag taactcatca atccgcgccg ttgaaccgct cgctttcgct
      781 gtctccgcaa aaaactgtcc aagcgttgaa aaaggcccaa tcaactgggt gagatacatt
      841 aagaaagcaa acaaggttcc catattcatt gacccacttg caacccgact ggcaccatat
      901 gcgagcacgc ccacaatcat acccatcatt aatgtcgtca ttactggctg ggcaaccgcg
      961 tcataaactg cttccttcaa gcccaagcga tacaaacgat caatgcgggc atcaccggtt
     1021 ttcttttcga ctgcttcagc attggaactt ttgaccaagc gcacagcgcc caacacatcc
     1081 ccagcctcgc cactaaaagc tgccagattc tcttgtcgtg aaaaagcaat cttacgcgac
     1141 tgagtggcaa ctggcaggaa gatcagaata acaagcggca caacagcaaa cataatcgcc
     1201 gtcattttcc aatccatcat caacatcaaa atcagcgcac cgatcagttg catcaaggct
     1261 gtgaccatgc gcggtaccga gttggcgagt aaatccttga cttgagtaga atcatttacc
     1321 agtcgcgacg tgatttcgcc agacttggtg gtgtcgaaat aactgactgg taataccaaa
     1381 agcttggccc acagcttatt gcgtaatttg gcaacgacat catcgccaaa aaagcctaac
     1441 acggcacctg aaccagcact gatcaacgct gaaccaataa acagcccgac aacgccaatc
     1501 accaaattca tgttgaccgc atgccccaac gcattaatca gcgacttggc aatggttggc
     1561 acaattaatt ggccggccgt cgccactaat cccaaaagca gcccaagacc aagctgccag
     1621 taatgtgggt gaatggtact gattagtttc atgaaactac ggaaatcgaa cttttttggt
     1681 gttgactgcc ttttttcggc tgccatcatc gtggttgaac gttgcatatg catgtgcctc
     1741 cagttatcag ctatttaaaa tagttagttg cttatatatc taactaacat tgtgctagcc
     1801 taatcctttt gttagtctat gtcaacaaca actaacaaaa agaactgaac aaattttgtc
     1861 cagttcttaa atcaccttga atttccatgt cctcggctag tgcgcttgca aatatgcctg
     1921 aacgaaacta atcatgtcgc gcgactgttg attaaacaat ggcggcagtt gatcaaagtc
     1981 aaagtattgc aaggccaacg tttctttggg atccgcttca gccaaactgc cgccgactgg
     2041 tttgacgaga taaaaacggc agatgatttg ggcctgatca ccattgggat aagttgtaaa
     2101 tccttggtcg aaagtatgca gtgccttgac tggttccacc agtaaaccgg catcctcttc
     2161 catctctcgt tgcaaggttt cgacaaaggt ctcaccgtac tccatcatcc cacctggcaa
     2221 gctccagtta ccggcatctg tccgtttttg cagtaacaat tgtccctgct cgttcaccac
     2281 cgcaccggca acggcgttta aaaaaatcgg catgtgtccg actttgctgc gaatctctcg
     2341 aatataattt gccacttaac tgcctctttt ctcgaatcgg ttaatctgat tatcaagcag
     2401 tcagccaatt ggcgcaacta gctgcaagac aattcgaaca ctttgtctag acgctggtat
     2461 gcttaaaaca ataagctcac ggtaaatggt ccaatcaaac aaccccaacc aaatttgacc
     2521 gcaaacaaat agacgaccat cctcgcaact aaaagtcgca atgacagccg tctttttcaa
     2581 tcacttaagc aattgatttt tggattagtc cagcttgctc ttactgttga cgttcaactt
     2641 ttcgtcgaag tcataaacaa caggttcgcc agtcgccatt tccaagttca tgatgtctgc
     2701 atcggaaatg ttttcgatgt acttggtcaa ggcgcgcagt gagttaccgt gggcagcgat
     2761 gataacattc ttgccagcca acagatctgg tgcaatatga tcttcccaga atgggataac
     2821 ccgttcgagg gtcactttca ggttttcgcc gccaggaatg atccgtgggt caagatcagc
     2881 gtaacgacga tccttagcag ctgaaccttc gtcagttgct ttcaacaatg gtggcaaaac
     2941 gtcatacgaa cgacgccaga tgtgaacttg atcggcaccg tatttatcag cggtttcctt
     3001 cttgttcaag ccttgcaaag cgccatagtg acgttcgttc aggcgccatg tcttcatttc
     3061 tggaatccaa agttgatcgg attcttccaa gacgtaatgc agggtcttga tcgcgcgggt
     3121 caaaactgag gtgtaagcct gatcgaattc aagaccagct tgcttaacca attggccagc
     3181 atgctttgct tcttcgacac ccttttcact cagatcaaca tccacccagc cggtaaattg
     3241 gttggacaaa ttccattcac tttgcccgtg acggatcaat actaatttcg ccatatcaga
     3301 gaatacctcg cttttatgat ttgacagtct tctgcctgtt tacagaatct catgttacac
     3361 cattttcagt aagttcgcac ccgctttctc tggtatattg gaaagggatt gttgccaaaa
     3421 gaacatacga cgcaaattaa ctgcggcttg atttgctttt ggcaactttt agcacgcatc
     3481 acaatcataa ttgtcacctt ttactgaaaa tatttctgga ggttcatgtg aaaaaaattt
     3541 ggctatcaat tgctggcgtt tggctcatca gcgtcattta ctttatcgtc tatctgacag
     3601 ttcccgccat gcaggttgcg gttaatgcaa gcggcctgtt gtcattggtt catggtgtca
     3661 tggatctaat cttacttggc ggtgcgtttg ccttaatcgc aggcgcgtta tatcgaatat
     3721 ttcatcgtcg ttaatgataa agacagtttt ttgttatact ctttttgtac aactttaatt
     3781 tcattcttta tattcagcac tcatacatat ctttggaggg aacactatgt ttaagatttg
     3841 tccaaattgt ggtgcgcata atactgccac cgctaaattt tgtacccgat gcggcaccag
     3901 tttagccggt gtcgttgcaa cagccgaaac ggcggttcaa agtgcacaac cgacttctga
     3961 gaatgaagcc tcaaccgcca acacagcagc tgttagcgaa caatcttcag tgccaagcag
     4021 tctaacttca tcgtcagctc agaatcaacc tgtaacgccg caacaagcgc aaagtcaggt
     4081 cacaccgcct gacaacagtc agcagcaagt gccaccacaa ccagctggca cacagacaca
     4141 aagtcagcaa acggctcaag gaccagcacc gacagcgcag ccttaccagc aggctgatca
     4201 aacgcagcaa caagcacaaa caccgccaga ggagccaaat cccacggtgg aggctaccaa
     4261 aaagtatgct ggcagttact ggcgctatct agtcgacagc attaaacatc ctgcgactgt
     4321 gacgcgacca tatcaccagt attttgggct aaccagttta gccatcacga ttgttagttt
     4381 ggcattaacc attgccttga tgactggttc cgcagtgtcg tcattgccag gcgcaattgc
     4441 tagtaatgtc ttgatgacct tcctaaaatt agtctttcta gtggcggtcc tgatgattgc
     4501 ggtggtcgcc gtctattact tagtcgtcaa cggcatgctt ggcgatcggc gtcgatcttt
     4561 tctgacattt accaccgagt atgcctttca ctgcaactgg atggtctttt tctcagtgtt
     4621 cacgctgctc atgcaaatgc ttggtatgat taacatcggt tcaatcttcc tgatttggtt
     4681 gctgctatcg ctgggcagcg ggttattcgt catctctggc acgtatatgt tgttcaccgc
     4741 tcagtcaacc aaccgttttg ataaaatcta cgcctatcta atcgttggta ttttactagt
     4801 catcgtgttc ttgatcatca tgacgttcgg cctttcaagt attctcggcg gcattggtca
     4861 aggtatcaat gattttggcc gcagctttaa cttttagaca agtatctact gcctaatcca
     4921 acggcttttt agacaaaaat aggccttaag acctgacaca tgggtagtgt cgtgatctta
     4981 aggcctattt ttttggtcgt cactcaattg accaatgcct ctaggttttg tgcaagactc
     5041 acggtatcag ttgacattgt atgattgcca aacaagacca caccgctttt cgcatcggct
     5101 cgaaaatagg ctaaggtgct gaaactttcc ggattgtcgt tgtacattcc ctgtaataac
     5161 cgctggtcgt ctaaccacat cacgccactg gcatatggat taccatcccc ataattggcg
     5221 ttaatcagct gatgatagac ttttaacggc atgattttcc cagtctctgc cgcaatgatg
     5281 actttagcca agtccgttgc gctcatatac acactgccgc tgcccaacaa agtcgacaac
     5341 agggcgttgc tcagctcatc tggttgataa tcgttatcac cggctgttaa gtagccctgc
     5401 gcaacaggca tctgcgccgt cagcgccgta aagttatggg tgtgcgtcag ttgtagcggg
     5461 gtgatgatcg tttgttgtaa gacattcgca aaacttttac ccgtaacttg acgcacaatc
     5521 cccgctagca ctgcatagtt agcattagca taaatgaagc tgtggtcgcc agtcgatccc
     5581 atctgctcga atgtccagtc caaaatagcc tgctccgagg ttaaggtttg atcaggcgtt
     5641 agttcgtcca tttgaatacc agaacggtga tccaataact gacgaatcga gatgtcctta
     5701 ctatgatcaa ttttcgggaa aaactcggcc agtttggtat taaatgacag tttgtgttcg
     5761 gcaatcaaat gaccgatcac cagtgccgtt aagtattttt caaccgacgc caaaggaaac
     5821 attgtctcgc cgttattggc ttcatgttga ccatgatccg cgtcaccgac gccgccagta
     5881 taaacaatct gcccgttttt gatcaaagcc acactacccg tgaacgccgt tttcttaatc
     5941 aaggcttggg catgtttgcc gacttgcgct tgcggcaccg gacgcgccac aattttacta
     6001 gcttggcgtt gatgatacac ccacgccatc gttaagcccg ttgcagccac caacgctacc
     6061 gccaatacaa tcacaatcag ccaacggtgt ttatgcatcg tcatcgtgct ccttgggctg
     6121 cggcacactc gcgtatgttg attgcttgtg cgccgtacca gcaattttct taacgcccaa
     6181 tacatctagg aaaaaggtaa agatcggaat gccgacaatc aatccccaag tgccaaataa
     6241 ccgctctgcc actaacaaaa cgacaaaggt aaagaaaact ggcagctgtg ttcggctgct
     6301 catgaacttc ggattcaaga cataagcttc tagcacatga atagctgcaa tcatgatcaa
     6361 aatggtgagg acatcttgcc aaccgccgac ggtataacca ataatcgtga gcggaatcaa
     6421 ggaaataatc gctccggcaa ctgggatcaa ggaaagtaaa aagaccataa tcgcgagact
     6481 aggggtgttc ggcattttta agaatagtag tgtaatcgtt gtgatcacgg tattcacaac
     6541 tgcaataaaa atttgtgctt ccatcacaac gccaaaagta ttgataaact tcatcgcgaa
     6601 atattgcaga tctttgaaat accagccgaa cggtgaatcc agaaacagtt ggccaaacgc
     6661 aggcaagctg tcaagctcaa tcgtgaaaaa gaaactaaga atgaaagaga caaacagtgt
     6721 caatcccatg gcgccgatat tgccggcgta ttgtagcacc gtggtcacgc cagtcttaag
     6781 ttgttccgtc aagttgagac tcttcgtgct ttgcagcacc cattgcatga cctgattgtt
     6841 ggcgaacgcc tcactgttat aaaagttttg cacagaatta aacaagccaa tcgtctgatg
     6901 aataatcgct ggcacgtaat gcactgcagc gtagactagg cctaggatca caagtatgta
     6961 aactggcacc acaatcacaa atgggcgaat atgaacatgc cgctgaacag cgtggactaa
     7021 gcggctgact aggaacgcga aaatgaaggt caacaaaata tcgctcataa tgctgcgagc
     7081 aaaccacaac aagagaaaga ctgaaaacaa caccactgtg cgcctaaccg gaagattatt
     7141 gatgaacttt tcgtaacctg acatactttt ccccacattc ttaacgagat acactaagcc
     7201 tgccgcaaaa tcaaaaaaag cgcaagcatt cgctcgcgct tgccgaaatt ataagaaaac
     7261 cttcaagtgt tgcttcgttg cctttttaac tgactgaagc tggccttgaa taataatgcg
     7321 atccacttcg ccttcagttg gcgatgcaca cgtcaccatt gtaatcagtt tcttaccggc
     7381 aacatcatca atccactgaa cttgggtttc attaacaacc tgtttactgg tcactttata
     7441 cgagtaaact ttcttcatat cggtgatata aatgatgtcg tcttgcttca catttttgag
     7501 cggtgaaaac aaaatacctt gattggtcat gtagtgacca gctaaagcgt aattaccttc
     7561 gcccattttt tgatcggctt tcatcgtgcc tgcccctgca ctgagattct cgtttgataa
     7621 ccctttaaaa ataggcaatt tcaaaccgac actgcgaatg gcaactttgc caataggatg
     7681 caggtcacgg ttaagcgcgg cattgccaac tgtattgata tcaagcgctt tgaccccttt
     7741 gaaatcaaag gttgctttgc gtttttcatt tttgttgaca ttgtcacggt caacttgtgc
     7801 catcgtccac tggctaagat gatcgaccac aaataattta atgggttcat tgaagatcag
     7861 cgctaatccc agaaggatac cgagcgtaaa aatggttcgc caaagccaac gatgtttacg
     7921 cggtggctgt tttttattag attgtgtcat cgtcatcctc ctcggggaaa tcataccttg
     7981 aaacgttgtg agattcaagc aagggtgctc gggtgaatgg ctcaattgcg gtttgttatt
     8041 ttgataaata agttgttttt ctgttctgct gtcgttggaa ggttatcctt agtgtccgag
     8101 ctggctacgc ggcgattcgg ggtggcgacc gcgaagctag agtggtgggc acgacttcga
     8161 gcccacgcgc aaaacccgcg cgcagtctcg aagctcggcc tccttgtagg cggtaaaccg
     8221 ccaacaagga tttcaccact gagcccatcg ccgctccgcc agctctccag attctatttt
     8281 aattttaaaa cggtattctg atctactcat gcaagaacga cccacaattg aagttctaca
     8341 tgccccacct gccatggtat actattgaaa gtttgcatag gaggcgcctg ttttgaagaa
     8401 gctttttcaa ctctataagc gttatgaaat gatcatcaat tacctgttta tcggcggttt
     8461 gaccacgttg attaactttg tcacgttctt cgccatgcgg tattttggta ttggcttagt
     8521 tttgaccaat acaacggcga atatcgtcag tgtcattttt gctttttttg ccaacaaaag
     8581 tgtcgttttc cacagtgact actcaagcaa gaaaaagttc tggttcgagt taatcagctt
     8641 tcttgtgttg cgtggggtct ccttgttgct ggataacttg atcatgatca tcggggtcga
     8701 ttggctgcat agtaatgaga ttctcgtcaa aattttagat caggtcatca tcgtgatcgc
     8761 caattatctc ttctcaaaat tgattttctt acgcaaaaaa taacttcatg aagtgtgctg
     8821 acccctgtct ttgttgcagg cggctagcac gcttttttaa gttggcagca aaaatagttg
     8881 cttggtttgg tgcagtgtca cctgaatcgg ggttgaatat tcttcgccgt caatttgaat
     8941 tggtacagtc gctgatgtgg caaattcaaa tgtttgccct tgtgaatggt gcatggcgcg
     9001 gtgaactgaa cggccactga gaatggcaaa taggacctga agcaaaatgc ccaatttttc
     9061 gcgatgcacc tggacaaaag acaaggtgtt gcgattatct gccttatcag gaaacagtcg
     9121 caaaccgccg cctaagaatg gatgattagt aaagacattg agataagcat tgtcgattgc
     9181 cgtggtttta ccgtctactt gccaagtcgc acgaaacttt ttttgttgtc gcagtgcttt
     9241 tagaatactg gcagcatacg aaaaatgacc gagttttagg gcattcaatg ctgccttgtg
     9301 atcagaatgg ttcgtttggt aaacgatttg ggcatccatt ccaataccaa agttattaat
     9361 aaaatactga gtcccgtact tggccgagtc tgccaccccg attttcaagg catgcggcat
     9421 tgccgttgtc aaagccgccg cagctttttt cgggtccaga ggaatatggt tggcgcgggc
     9481 aaaatcatcg ccggtcccgg ttggcacata gccaatggcg acttctggat gaccttgtcg
     9541 ctgcaaccca ttcacaacat cgtgtagcgt cccatcacca ccaatcacga tcagttgaag
     9601 atcgtccatc ttgtgttgat aagccttgat gagtcgttcg gtcaccaacc tggcatcacc
     9661 agccttgcgc gtctgactaa tatgcagtgg cgcaaagtga gactcaatga ttgcaactaa
     9721 ctcaggtaat tgctttttcc agcgggcatt ccccgcactg ggattcataa tcacttcagc
     9781 aaaaggcatt ttccttactc cgtctcatta gataattggt caaaaagcga tgatattctt
     9841 tatcagcgat gaccactttt atcatatgat acctttttca aggcagctag acacgtattg
     9901 cgcttgaaaa atcacctttc tcaatcgccg gcaacacagc gactaaaaac agcacggcca
     9961 tcgccgtact gcttaatact catctttctt ctatcaccag ttacgccaca ggcaccttgt
    10021 gtgtcttcaa gaattcactc agcggtacca atctttccgc gtagtaacgc ttcttgaacg
    10081 cagcaatcgt gtctgcgtca aactggttag gatccaattg cagatgctca actggaattg
    10141 gccgttcgtt ggtgattttg gcatcaatca aggttggttt gccggcagcc cggttgtctt
    10201 cggctgtttc gaaagccgct ggtaattcgt caacttgggt gacagtaatg ccggtcatac
    10261 ccatgccttt cgcaaccgtc gcaaagtcaa tcgccggcat gtcgatcccg aaccactcgt
    10321 gaccatcgtc ctcctgctca tcttcaatgt accctagcgc attatttgaa aagaccacat
    10381 tgatgattgg caaatgataa cggacttcgg tatccaagtc ctgcatcacc atcgccgcgg
    10441 caccatcccc agccaggtta aagacctgtc gctttgggaa gctcaattga ccggctaatg
    10501 cggccggcaa tccagcgccc atcgtggcaa acaacccact ggtggtccac gcttggcgcc
    10561 cattgacttt cagtaaccgg acagcatttt gggtaacatc cccgacatca atcgcaaaaa
    10621 tggcatcatc agtagcaatg cggttaattt ggccgaaaac tggttcgaag cgcattttcc
    10681 cggttgtccg ggtcatcata tcgtcattat actgatgcca atttttcacg ttgtcgacat
    10741 tggcttgata ccagccgctg cgtggtgcat cgtcactacg atcaatcatt ttcttcaagg
    10801 ttgccggagc atccgccaaa atggcaacat ctgtgtgatg gcgcttgccc aatgtcttcg
    10861 aatctgcctc gatctgaata aacttggcgt tcggtgagaa catgacttca gcaaacgggt
    10921 aattcgaacc gacaaacatg atcaagtcag caactcgcaa cgcttcattc gctggttttg
    10981 aagccacccg agctgcagaa ccaagcagtg attcaaattc gtaagggata atcggcttgc
    11041 caagtgctgt cgtaatgact ggcatctgta gctttctggc cagcgtcatc accgtatcag
    11101 cagccccacg gacgccttgg ccaacgtaca tcacgggccg ttgcgctgcg ccaattaagc
    11161 gcaacgccgc atctacttgc tcgtcgctgc cagctggtaa aactggggtg gcgtgggtag
    11221 ctgctgcact gtagtagcca tcggctggaa tttcttcggc tgccaaatca ttgggaatca
    11281 caacaatcgc agctccacgg ccggcataag cacggcgaat agcctcgtca ataatatgcg
    11341 gcagactagc cgccgtggta accgtccgcg catacaaagc ggcatcttga aacatcggat
    11401 cttcatccag ctcttggaag aaatcgtaat tcatgaagcg ttgttcaact tgacccacaa
    11461 gaaataacgt cggcacctta tccattttag cgtcatacgc cccttgaaat agatgggttg
    11521 cgccgggtcc cgctgatcca aatgccacgc caatatgccc agtcaattta ccatccgcta
    11581 ctgcagctag cgcaccgacc tcttcatgtc ggacgtgaat atactttaaa ttgtctttct
    11641 cttcatccag cgcatacatc atattgttaa aagtaccgcc ggggattccg taaacatgtg
    11701 tcacacccca gctctcaagt gtcttcaacg cggcgacacc agccttaatg gtctttacca
    11761 taagaatccc tcccaaaaag tgagcgcgaa caggcacgtt tagaagtcgg cacatatgtg
    11821 ggcttctgcg acgacgagcg cgttattcaa tatctctcgc ggttatacta gatttgtttt
    11881 aggcataaag caattatttt gttcagagca cgaggtgagg ttgggacatc attcacagcc
    11941 aacaacaagg cgacaatttc catacaaagc tgaaatagtt ggccttattc tcatggatca
    12001 attttattga gatttaaaga taccagtgcc aaggcggagc aatcgtaggc cagatggggc
    12061 tcagccgtgc aaacaacaca gcgaccgggt ttcgtcgctg atgttgttag gcgacttcga
    12121 gaccgggctt tgggttcgaa gcgccgtcac gctctagctc cgcgtcgcaa gccacatctg
    12181 gccggagatt gcggagtttg gcacggcaaa gaatgttagt cctaagcttc cgctcgatta
    12241 gccgtcatca tctaaaccgc ccaatcgcat aacaaaaaaa cggcgaaccc cccatatcaa
    12301 ggaaagcatt cgccgtcatc aaacttattt caaatcttca atactattaa tattcttcat
    12361 atacttcggc actgccaagc cgacctttgc accatctaag ttcacgccaa gatcaacaac
    12421 ttgattctta taatcagaat aaagttttgc tgacgtattc ggtaaccaag cagaaacctg
    12481 agcatcggca gctttagttg caactgaagc ccaaactggt tgtggttcca ttgcccgaat
    12541 cgtcacgtta taccctattt gccgcaaaac agttgcaaca acattggtgg atgcgatttc
    12601 cgaatcccac gcaatatagg tcatcgtcag tttaggtttg ccgctaacat gcgtcacacc
    12661 cttggtccac tgtgcgattt gttctgggtg cttcttaacg aaagctttgg ctgcctcggc
    12721 aggatccttg ccgccgttga ccgccagcat cacactggac atttcttcag gcgtccagtg
    12781 gaactgatct aatacctgat aagcttgcgg tgcatcctgc ttaaggccct tccgcacgat
    12841 tgtatgaatc tgttcggttt tgccgtaaac atttttagga tccttgagaa actttagtgg
    12901 aaacttggtg aacatccagt gcggcgtcca gccagtgacc acaatcggac gtttgtcggc
    12961 aatcgccttt tgcaacgtac tggtcatagc ggcggtggaa cttggttgca actgccactt
    13021 tttatccaca agaccataag ctttcagcgc tttgtctgta ctggtcatga ccccagcgcc
    13081 agcatcaatc ccagtaatgg tgtaattgat ttgcggtccc agcggctctt tagcgtcata
    13141 cttaggctgt gtgctgctgc aggcggcaag tgcaccgact gtgatcaaca ccgctagcgc
    13201 cgcggcaatc tttttcaaaa aagtcaaacg gccacctcct aacgactacg attgagactt
    13261 tgcgtgatcc ggtcaagaat gatggccaaa atcacgatgg caagcccggc gacaaaaccg
    13321 ccgccagcat cattacggcc gactgcaaag taaaccttcg tacctaagcc catcgcacca
    13381 atcatcgaag caataacaac cattgacagg gccaacatca tactttggtt gatcccggcc
    13441 ataatggttc cgcgggcaaa cggtaactgc accttcaaca attgttgcca accagttgcc
    13501 ccaaatgcga ccgctgcttc atttaaatca gctggtactt gcgtaatgcc aagctgcgtc
    13561 atacgaactg tcggtggcat cgcgaagata accgaggcta caaccccggg taccatcccg
    13621 ataccaaaga aagcaacggc tggaatcagg taaacaaagg ccggcatcgt ctgcatgaag
    13681 tccatcaatg gtttcaccac tgcggaaact gacttgcttt cggccgccca aattcccagc
    13741 ggaaccccga tgacaatcgc taacaaactt gcggtcaaca ctaaggttaa cgtttgggtc
    13801 atgtcacgcc agaaaccaag gttccaaatc aacagtaaac caagcaattc aaaaatcagt
    13861 aagctgcgat atttctggtc gcgtttcaga taccaagtta acgcaagtac tagaatgatg
    13921 aataaccaga tgggaataaa atcaaagaca gcttggaaag cattcacaat gccgccgatg
    13981 aagttcgtta aaaccccgaa gaagccggaa aactgggtta accacgcaac aaatgaatcg
    14041 acccagtggg ccaatggtaa tgtgggaatg ctgattaaaa tgttagacat tgacattgac
    14101 ctcctgtcca gataatgcac ctaagacggc accgcgaatg atgatcccgc gtaagcgatc
    14161 atgatcgtct accactgcaa atggtaccgg tgtagtggaa acggcgtcta gtaagtctgc
    14221 caacggcgta tccattttag tcgttggcac atcggactta acaattgagc gcagatcctt
    14281 ttgaccggca tcaatagctg accgcacgtc gtcggcgtcc aaaatgccga cgagtttacg
    14341 tttagtatcc acaacataca aacttgaaat ttcattgtcc cgcatccgcc gggcagccaa
    14401 acgaggacca tctctatcaa tattgactgt gttggcccga atcatcacat tggcagccgt
    14461 ataaacctgg ctgcgatcaa caccttcaat gaatttctca acataatcgt cagcaggctg
    14521 gctcaaaatt tcttcaggcg tgccaatctg aacgatttcg ccatctttca taatcataat
    14581 gtgatcgcca attcggagcg cttcgttgag gtcatgcgaa atgaagacaa tggttttttg
    14641 catatcttct tgcaagtcca ataattcatc ttgcatatcg cgacgattca gcggatcaag
    14701 tgctgaaaaa gcttcgtcca tcagcagaat ttcggcatcg ctagccagcg cgcgggctaa
    14761 accaacacgt tgctgcatcc caccagacaa ctgatctgga tattgatcgg caaaaccatt
    14821 taagccaacc aaatcgagtg ctttgttggc tttcatctcg cgttcatctt tctccatccc
    14881 ttgaatctca agtccaaagg cagcattttg cagaacggtc cgattcggca gtaaggcaaa
    14941 gccttggaaa accatgctga gcttttgccg tctaacttca cgcaatgctt gcttatcaag
    15001 tttggcaatg tcatcaccgt caatcagtac ttgcccgtct gtcggttcaa tcaaccggtt
    15061 cagcatccgc aaggtcgttg atttaccaga accggaaagt cccataatca caaaaatctc
    15121 accggtttta atcgaaaaat cagcacgatc aacaccaacc gttgcgccgg ttgcttttaa
    15181 aatttcaggc ttggtcttgc cggccttcaa catttctttc gcgcgattca cgcgcttacc
    15241 gaaaatcttg gttagcccgc gaacctcaat ttttgtctcg gcattacttt caactttgtg
    15301 ttgcatctac tcactccttg ttttgaaaaa cgtttgtcat cgaattgaaa caatgctatc
    15361 cattctagag atagtttgtg tgtgattcaa atcacggaat ctcattttca ttttcgccgc
    15421 cattaagcgc cacatgacgt tctgtaattg atgcgcacaa aaaaagcccg tatccgcatg
    15481 aggttatggg ctagggacaa tcagcgattc gaattttgag agcttctctg aaagtcaagg
    15541 atagatgaaa tttagatggg atctttttca ttattcacaa gctgttaaga ttaatctctg
    15601 aaaaaggcaa gtgttcgtcg aatggtattt cgttgcctaa tgtgatttga tctgggccag
    15661 tcatggtgtc ataagccagc acgcgaacgc cattttgttt agcagtcgtg atggcagtca
    15721 ctagttcagg aaaacggtcc cgataaatgg tcatttggcg aatatccggt aattgcacga
    15781 tgaacaataa aaatgcctga tacccttctg cctgcgccat cgtcagcgta tgaacatgct
    15841 tgacggcgcg agttgttggc gcatctggga aagctgctag ggtgccatta gccaacgtga
    15901 cgcccttcgt ttcaacaaac cacgactggc catcagcggc tttcccagca aagtccagtc
    15961 gcgaatcgcg ccaagtcgat tctggatgaa tggcgtatgg caaggcgagt cccggcaatt
    16021 ttaaggtgcc agcttccaaa cattctttgg taacatgatt gggtgccaga ctgtcgatgt
    16081 tgatccagcg accttgccgt tgaacagcca gcaagtcata gtgcgttttg cgatttgggt
    16141 tatcaacata gcggacactg gctaatgatc ccggaatcaa aatttcttta ttgcgtccgg
    16201 tattattcat gtggacaggt tcgacggtgc cattcaggtc aatttcaacg gtaaagcgac
    16261 tcacccgttt gatgagctgc ccgacgctga cattttggta gtacatgcgt tacttccttc
    16321 ccttgttggg tgttggccgc catgaaaata gcagtcgcaa cgatccatga agaatcggta
    16381 cgactgctca tttttgctgc acttgaccga aatcagcgaa cgataatcac cgagaccgat
    16441 gcatcgcgag caacttcgct cgcaacatga ccaagacgta accgaccgcg gcgaacatgg
    16501 gaacccataa tcaccaaatc cggtttgaag gctgggatca cttcgtcaag aatggcagct
    16561 gctggccgcc cttctgcaac gatcggttgt gcgttttgaa cgccaaatgc cgttgctttt
    16621 tcgacgtaag tgtacagatc cttagccagt gtttcccggg ccgcatcaac atcatcaggt
    16681 gtcaatgatt ggaaaatatt gaggtcgccg gtttcaagta ccgacacgat ccccaacgga
    16741 atgtcataaa tcttggcaac cgtgcaggcg tagttcaatg ccttgcgcga ggagtcgtca
    16801 tcatcatcat caaccgccaa taacaaccgg ttataatgca tggattcaat cgtcaaatca
    16861 tcttcagtaa ccaaaagaaa tgcccccttg caagtttagg tatccctaac aatgccattt
    16921 tatcacatgt cgcccttatt ttccgcaaaa tactgcttaa accgaccaac ataattatgg
    16981 aacatatatt tcatcaataa ccagcgcttg aatgtcatgt ccggtttata aaagaccgtc
    17041 gtaccatagc gtttctcttt aagtaactgc aaggcttcct ttttagcttc gttatctgca
    17101 gaatactgct tgaaaacacg ctctggaacc cctagccaca atttatactt gctgtggtca
    17161 tcattaccat aaaccgttgg cgcgtccttc aaatctccca cgatgtaatc gcgaacaggc
    17221 cagctggcaa gattataccc atttaaagtg acgaaaaagc tactccggcc ttgacgaata
    17281 ttaatttcaa acagcttgaa cgtcttgtca cgatgatcat acttcatatc aaagttagca
    17341 aaaccggtga acttaattgc ttcgaggaat tttttgatct gatcgtacaa atcctgatcg
    17401 aaagctggca tgatcgcgac atagttaccg attgaagaag gcgtaggatc ctcaagtagc
    17461 ggatgaccta agcacatcat tttaacgtga tgatattgat caacataaca gttcaaagtc
    17521 cgcatgttac tgtcatcacc tggtacaaag tcctgcaaga tgagatcaga cgtatagccg
    17581 ttatcataga ttttggcaat cgtattcgtc agttcaactt gcgagtgaat cgtaaacgcc
    17641 tttttgcggc cttcaaagcg aatgttcaac cattcaacgg aatcagtcgg cttgagtgct
    17701 actggaaatt caaacggtgc cgtgatggtt gcgttgcttt catacatcga cttggtgacg
    17761 attttggttg ccggatatgg caaatgatac tcttcgcaga cttgatagaa gctctcctta
    17821 ctattcaggc gcttcaacaa ttcataatca acatatgggc agatgaacca ctggctcaac
    17881 tcatccttat gtttggaaac aagttgggca taggtgtccc cgcaagcgat taacaacagt
    17941 ttgcctggag catctgcatg taccttggct acctgccgca tattttcaat aaaagtcgga
    18001 tcggaatcaa aatgctcgat cagatggaca ttcacgatcc gcgaaaaacg cgttggagca
    18061 agttgttcgc gcgcataaac atcaatcgcc ccaccgatca tctcgtggaa cgaacgcgcc
    18121 ataccataca cattcatgtc actgccaagc aggatggggg taaaactggg tgcatctttc
    18181 atctgaatga taatctcctc gttcaataag acgcgaattc ggtcaactgt gcgtcttgaa
    18241 attttcattt taaaaccttg tctgccgatt caattattga catcaggcat cgttagactc
    18301 gttttgtaag acgcgaaggt gattttatca atcagcttcc gtccgttgcc cccgaattat
    18361 accataatgc cccaccacgt tcacttgcgt caggatacca taacactttt tcaataatca
    18421 tgaatcaaaa aatactaggt catggctacc tagtattttc tgaaactcac tcaaactgtt
    18481 caacttgtac gccttgttga ctcggcgcca ccacctgtac ttgccacttt ttccaacttt
    18541 cttgagcttg cgcctgtacc tgcgcggcag ccgcagatga gtctgtgatc gccagcatgg
    18601 tcgaaccaga accagaaatc aaaagaacac cgccggccgt ctgcaccact tgatgagccg
    18661 ctgaatagtc tggtattaat tccgcgcggt aaggctcctg catccgatca gtcgcaactt
    18721 ggcgtaataa cgacatgtcg ccatcagcca gtgcccgggt catcaaggta caacggccca
    18781 tttgataggt agcatctgca taagtcatgg ttcgcggtaa aattcggcgg gcatcagcgg
    18841 tactgacagc atagtcaggg atcaaggtca caaaatgcaa ctttgagctg accgtatact
    18901 gccgaacgac tggttcattt tgcgccatga tcgtggcaca tagctgcccg taaatcgctg
    18961 gtgccgcatt atctggatgg ccttccattt cagtagcaaa tcgcagcagc gccgtatcat
    19021 cccaaccggc ttgataccac gcattagcag cggcgatacc accaaccaca catattgctg
    19081 aactgcccaa accgcgggca ctcggcaccg ctgaatcaac cacaatccgc agattaggaa
    19141 caggctgatc aatcgcctcg gcaaatttgc taaacgcctg ataaatcaag ttctcactat
    19201 tggcgaaagc tgggtcatcg ccaatgatct caagcttttg ggtgctcatt tcaaacgtaa
    19261 aatgagcttt gagatctaag gcaagtccca gcacatcaaa gccaaccgct aagttagcgc
    19321 tcgttgccgg aacggacacg ctgatcatcg ttgaatacct ccttcgccgc cccaataata
    19381 gcttgaccca tatcggttgg tgccacaaca atcttttcct gcggtcttag ctgttgaagg
    19441 cgagcaagat tcggcggaat cgtcacaccg ctaacctgtt gcaacatttg catcgcagca
    19501 aagtcatcat ccggtacgtg cgattgtagt gccttggcca ccacgcgtgg aaatttataa
    19561 gggcttgcgg tggctaaaag cacattcggg gtgttatccc cagacgccgc ccggtactgc
    19621 tgttgaaccg cataaccaac agcagtgtgc ggatccagca aatacccatc ccgatgccaa
    19681 acctcgcgaa tggcatctgc cacctcttca tcaacagcaa aaccgccagc aaagtccact
    19741 tgaatcgcgg tcaacacatc cggccgaact tgatagcgac cagtcgtctc aagttcctgc
    19801 attaaatgcg caacatacgc gctatcttcg ccactcttat aatacaacag gcgttccaga
    19861 ttactggaaa tttgaatatc catgctaggt gccactgttt tcaaaaacgg tcggttgcga
    19921 tcatacacac cggttgccag aaaatcagcc aattcgctgt tggcattggc ggccgcgatt
    19981 agtttatgaa caggcaagcc tagactctta gcatagtagc ccgccaacac atcgccaaaa
    20041 ttcccggttg gaacagtgaa attaacctca tctcccattg aaatggcctg tgttttaacc
    20101 agttggctat acgctgcaaa ataatacaca acttgcggaa tcagtcggcc aatgttgatg
    20161 gaattggctg ctgacagggt tacttgctct gcctgcaacc gagcagcaaa gctagtgtca
    20221 gtgaacaagg ttttcactgc gctttgggcc tgatcaaaat tgccagcaat tgggaaaact
    20281 cgcgtattgt cactgcccac ggtcaacatt tggcgctcct gaattggact gacaccatga
    20341 ttaggataga aaaccgtgat cccagtctgc gcgacatctt taaacccttg tagagccgcc
    20401 gttcccgtat caccgctggt tgccgctaaa atcatgaccc gatcatcagg atcaagtgcc
    20461 aactgcatca agcgcggaag caactgcaag ccgacatcct taaaggcact ggttggtcca
    20521 tgaaataact ctaaaacatg aaaatccccg acagaacgaa ctggcgtgat gcgatcatcg
    20581 gaaaaatgct gatgataggc aaaatgaatc gcttttttta gtgagtcggt gttaaaatca
    20641 ggcaacagga tcatgagaac tcgctgagca atcgtttcat aatctaaatc taacagttca
    20701 tgaatgttca gcgtctgatc ggccaaatgc ggcaggacaa acaaaccgcc ttcttcagaa
    20761 ataccttgtt tgattgcctc tttgctggtt ttgctaacct gatgatcccg tgtgctcgta
    20821 tatcgcattt gaagaactcc tatctcattc ggcttgaatt aacgatatgg atatgataat
    20881 ctgttcgcat tagaaaaaca agtgtctata ttttataaac aaggagctga gaatttatga
    20941 aaattgccat cttaggtttt gggactgtcg gcagcggcgt ttacgatatt attgcaaatg
    21001 gtgatacccg aatgcgcgtc accgctattt tcattcggcc aacgcaccct gcgaccatgc
    21061 ctgagatgac aacagacctt gacgccatct taaacgatcc tactattgat gtgatcgttg
    21121 aaacaatggg cggtcttcat ccagcacatg attatatttt acaggctttg cagcacgata
    21181 agcacgtggt taccgctaat aaagccgttg tcgctaaata tttgccggag tttaccgctg
    21241 ttgctgccca gcatcacgtg caattttact tcgaagccac tactggcggc ggcatcccgt
    21301 ggattcgcaa ccttgaacgc gccgcacgca ttgatcagat cgataccatc gaaggcattt
    21361 tcaatggcac tagcaattat attctcgatc agatgcaacg cgcccacctc gattttgacc
    21421 ccgttctcct agccgctaaa gatatgggct atgccgaagc cgatcccagt gctgatattg
    21481 atggcgagga tgtggtcaac aagctgaaaa tttcggcagc acttgcctac aacatggccc
    21541 caccacgtga tgtcccaact tttggtattc gcaacgttag caaagccgac attgactttt
    21601 tcgcaagtca acatcaggtt ttacggttga ttggtaaaag taaacgtgac ggtgaccact
    21661 atagtatggt cgtggaaccg cgcttgtatt cagaaaccgc cttggcggcc aatacatttg
    21721 aaaacttcaa tctaattcgc ctgcatggac aaacgattgg cgacctgcaa ttttatggtc
    21781 aaggcgctgg aaaatacccg acagccaacg ctatcgtgca agatctgtac gatatccttg
    21841 aaaatgcccc gcatctggac cgtagcttcg atcagccgct gcattttgac gccaacctga
    21901 atgtcaccga ttacgttttg cgcgccgatc ccatgacctt cgcgatgttc aatgatcgcg
    21961 aaaccgagat cgtcaatgac cggctggtga tcaagcaaat accaactggc gacatgcaca
    22021 aactcatgcg cggcgtttta gccattgatg ccgatgcttt tatggcagca atcggagaca
    22081 gtgagttggc tgctaaagac gtccttcacc agcgagatca ggaggtgatc ggatgaaggt
    22141 cgttaaattt ggcggtagtt ccgtggccga tgccggtcaa ttccagaaag ttaaagccat
    22201 aatcgatcag gatgtgaatc ggcaaatcgt cgtgattagc gcagctggaa aatatggtaa
    22261 tgctacccga aaattaactg atacgctcta tttaattgct gacggtatgg aagccggtcg
    22321 agatgtcgaa ccgctgttta atcaggtctt ggctcggcta gaggccatca acattgcgct
    22381 gcagctcaat gtgccgctca tcaaactgtt gcatacaatt cgccatcatc tggccattcg
    22441 ctattctcga gactatctgg tctctcgcgg tgagttcttg acagcccact taatggcagc
    22501 ctacttaggc tatacttttg tggacgccgc caatcttttg tttttcaata aagcaggcgc
    22561 cattgatgaa gccaaaactc agactgctta tcaacaacta gccagccatc atggtatcgt
    22621 cgttcccggt ttttatggtc gcgacgcaga cggacatgtc aagctgatgc cgcgcggcgg
    22681 ttctgacatt tctggtgcat ggctagcacg cttggcccac gctgatctct atgaaaattg
    22741 gaccgatgtt tcaggcatta aaatggccga tccgcgtatc attaaagatg ccgacagtat
    22801 tgatgtgatg agttacgacg aattacgcga actcacctac atgggattta gtgttttcca
    22861 agaagaagcg gtgcaaccgg tccgtgaatg tggcatcccg acgcgtattt tgaacaccaa
    22921 tgcgccagaa gacccaggta cgctgatcat tcatgatgat gaccccgcca atgatctcaa
    22981 aacaatcact ggtattgctg gccgtaaaca ttatttggtc atcacggtcc gcaagtacca
    23041 gctggccttg cacttagaag tcattcaaca tgcgctcggg gtagttgcag cgcaccatct
    23101 cgttgtcgat tatctgccca cgggcattga cagtttcagt ctgctcattc gtgaaccgcg
    23161 tcgtcaagtc tcggtacagg agctgaccgc tgaaatcgcc gctgcctgtc aaccagacaa
    23221 aatggaagtc accgaaaatg ttgcgttaat cgccatggtt tctcgtaaac ttcgacaacg
    23281 accagccatt gccggaaaag tcctcgctta tctggatgat aacctgctca acgtacaact
    23341 cgttagtcag accaatgacg atatcaattt gctaatcggc gtacatgatc ttgattacga
    23401 caaagctgtt cgggtcattt atagcagtat tcatcaaaac tttcagcgcc cggcgcctta
    23461 tattgagggg attgcctagc gcgttacaag tcttgaatcg catttaataa aaaagcatcc
    23521 tttccgcaaa aatttggctc tacgtcaact ggtgttgaag aataaattta tcatttgagg
    23581 cggttctcca tttggggagc cgtctttgtc atgttatgcc gtgatttggt agattcgttt
    23641 gaagaagttc agctgattct tgaagccaaa acaggatcgt ttgagtgact tgatgaggcg
    23701 gttaacccct tcgatcggac cgttggaata a
//
