LOCUS       c00016_JADOXS0..       11099 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JADOXS010000008.1 Bacillus subtilis strain 168(rho10) 1L10_contig_8,
            whole genome shotgun sequence.
ACCESSION   JADOXS010000008
VERSION     JADOXS010000008
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-21 01:50:24
            Original ID  :: JADOXS010000008.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11099
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11099
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[829:1099](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      830..1099
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..11099
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11099
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             96..830
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 103.3; E-value:
                     2.5e-31)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_1"
                     /transl_table=11
                     /translation="MITAEECRTYKEFVDLYQSYLYPLLGARLSRMYSPKNKVIIDMGT
                     GPGYLSIQLAKRTNAHVHAVDINPAMHEIAQEEAKKSGVSSLISFDLEDVHHLSYADQY
                     ADFIVSYSCLHHWEDVVKGLKECYRVLAPGGKIVILDTFNPQGSHLEIMRKQIKEPEYF
                     RFVREAFEESYSFEDIHQFVQDAGIPNYSLETFHFLPEDFIESLDELEDAPLWEQNDQS
                     TDHEIESVTWMLTIEKEKEGAL"
     CDS             830..1099
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_2"
                     /sec_met_domain="PF05402 (E-value: 1.9e-12, bitscore: 40.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.8e-09,
                     bitscore: 30.6, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 1.7e-09, bitscore:
                     30.4, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINESTVLSKNPEMPSRKYLKSIIIEPGITLNEMASDIYNHIDGK
                     VSIHDICSKIVNEYDVDYQTCLEDCMELFELLIDHEAIKVKQGA"
     CDS             1103..1585
                     /locus_tag="ctg16_3"
                     /transl_table=11
                     /translation="LEKQKVLALPDDVHELSTHRSKSIVNYIITLLAFAKKQGLTHQDI
                     VSWIHEQYEERGYYDEWRHINSQQPVGSFVELFIKGRRLLYDKIELFETEDKYVVNTHT
                     WYEKEPSEAFFYFEIDPEEFSAYASILAIENAKRLGIKIDIVKETDVETAYIYKHQ"
     CDS             1606..3849
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 407.1; E-value: 2.2e-123)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_4"
                     /sec_met_domain="Asn_synthase (E-value: 2.8e-95, bitscore:
                     312.9, seeds: 78, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 1e-44, bitscore: 144.4,
                     seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGLAGIINLAAPRSQECTFHILKGMADAISYRGPDDEQYHIDSK
                     VGFAFRRLSILDLVNGQQPFLNEDGSIVVMVNGEIYNYKELKASLHNHMFKTTSDCEVI
                     VHLYEEKGIGFVDDIIGMFSIAIWDKNKNKVFLVRDRFGIKPLFYTELKHELIFASEIK
                     SLFSHPHCPRQFNWKEALSDIWLSGEAASNHKETTSFFVNIQNLDAGHYLEINLTTNER
                     KTASYWSLQDILLRQGYRENLHPDDLIEGYRELLADSVHRCLQSDVEVGLFLSGGIDSA
                     AVAHFAAEKQDLHTFTVLSQSTFTNEDAKYAHWLAKDLHLPNHQVLYQLGNDELLQPES
                     YKHLLWICETPFCGPEQLYKFHLHKYAKAIRPNLKVMLTGQGSDEFNGGYSTTLSPAEN
                     PSWEGFIESVNTMEMNRLHRLQGNIFRVWEEHFGLSPINLSYLKSNDSSQADPWQSYVL
                     TKYRDLQMYNCWHEDRIAAANHIENRVPFLDHRLVEWVCGIPDGLRKDLLWDKSVLRKS
                     LTNELHTSYTHRPKVPFFYGKDVRYTHKMMFHLLKKNNYQLIEEAFSHSDASSIIQVEH
                     IHAIMTYLEDDPEFTNFEFLLRLVNMGLLSKMTKETPSVQLDITSHLESITIKDWHSQE
                     GDIASRLNISANKCEGQDILALNPGVTLLRPESDSEHCIYIAEEGFIQFIVSEEDVGAW
                     LHILCDINGKDTLHTILDRHGVSLEEVAKYIQEAIEHNIILIKQKNLPEGAYR"
     CDS             3846..5045
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 97.4; E-value: 1.1e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg16_5"
                     /transl_table=11
                     /translation="MSIFYSFSALRGLAMGIFSPIWILYLISKDYDFLQIGLMGAVLEI
                     AKLIFEVPSGVFADRYGIKISIASSFFFSILTWAFFPFIDSAAICILAMIIWALSDSLI
                     SGSFETWMSRVAGEDRFGKEMMKNTQLLITFLIIGSIASGYLYSLNIYFPFLLVMVIYL
                     LLFIWMSVFIKVPSVSETNHGDQNQHDSIKIIKESLKIIFNKKRVLLIVIAGFFTATAY
                     DTISRYWQPFLSDLGFSEKSLGYIFALGGFTALVLLTLTIRFEKKIEKNPYLALTSLDS
                     MGMVMTFLLSRAFRPLGIPCTAFLLAIEDIHHPIVTSYLNKFFPDSYKNTLFSLNSGVG
                     AIGEILSGVIFGIISAAFGLSAMFVVVAVFLLIPIILYTIVPKIKDNDMKVQIEKSQQV
                     "
     CDS             complement(5109..6341)
                     /locus_tag="ctg16_6"
                     /transl_table=11
                     /translation="MVKSFRMKALIAGAAVAAAVSAGAVSDVPAAKVLQPTAAYAAETV
                     FSQNNGASGFLPGRYDVQAMAPAMFNWSRESRFAGNTDGTLKWQNDIRTTPQNGAGAVI
                     DGDGTVYLHSRDGEMKAFNPDGSVKWVTGNLGKTYTQSPVLGTNGVIYLASYDKKIYFI
                     DKETGEILTTVPLSGGPSSETVIGSDGTLYFSTLDNYVHAIKPTSKSTWTERWKLKTNG
                     VVSSVPVLAKNGTVYVGTYNYVFYAINSGTGQVKWSRTTSNAFKGYPVIDKDGNIYAGN
                     QDGQLYAYTSTGSLKWTFPLNGFSSSSPAIDHNGNIYIGSGSGELFSISKNGDMNWSFY
                     TDGPVRTAPLIDAKGTVYFGSDDMKVYAADANGNELWSYQTDSNVVSSPQLAEDGTLYI
                     GSYTKLMAFGK"
     CDS             complement(6442..6867)
                     /locus_tag="ctg16_7"
                     /transl_table=11
                     /translation="MSKKNSVAIMTTISAFLFCAVIVAASLSPLAGTGAAANQFNSAGM
                     WSAVGMILVLYFIPFLVYMLGVDAMRYVMAVLCGFGLLIHLSSAGFILMFSFFSDHLLS
                     EVIFVLGVSLAAAAVNVIWFVAAFRSGAEKTSVNTLT"
     CDS             7124..7579
                     /locus_tag="ctg16_8"
                     /transl_table=11
                     /translation="MEKPAGFWIRFLAYFIDGIIVSVPSYIILFIINSVFVAGAVATNP
                     YMTEEEYLVKYMTLAFLPTMLIMIVISVLYYGLLTASKMQGTLGKKILGLKVVNEQGER
                     VSVGQGIGRYFAYILSGIIFYIGFIMIAFGEKKGLHDIICKTRVVYK"
     CDS             complement(7609..8817)
                     /locus_tag="ctg16_9"
                     /transl_table=11
                     /translation="MSSLQPTLTNERIGVLDVLRGMAIFGILFVNLAHFSYPDMYLSML
                     GKENFFMDKWSEADFAAADILKFFIQTKCILLFSFLFGFGMVVMMERAENKGKRFVPLY
                     VRRLMALLLFGTIHAFLIWDGDILTEYALLGFVLLLFRKAKPKTLLIWAVSLYLLFSIP
                     FMLTSFDQSNGQEWVQAVTQQAKQAIHVYGSGSLKDIAEQRIHDRLVYMSSNGMLTYNP
                     LNYFFASIPYFSMFLLGAAAAKSRYLHEPEKHRKGLKRLWMAGLVIGIGAQVLYSVTDK
                     EICLLIGAPFLMFFYVTTVVYLYHKTRVRTVLQSFSAVGRMAFTNYLMQSIVCTWIFYH
                     YGLGLYGKVYPAAGVLITIAVCAVQMVFSHLWLRVFRMGPFEWLWRSATYLSWQPIAKK
                     TKV"
     CDS             complement(8925..9938)
                     /locus_tag="ctg16_10"
                     /transl_table=11
                     /translation="MKTLCTHSLPKEKMPYLLRSGEGERYLFGRQVATVMANGRSTGDL
                     FEIVLLSGGKGDAFPLHVHKDTHEGILVLDGKLELTLDGERYLLISGDYANIPAGTPHS
                     YRMQSHRTRLVSYTMKGNVAHLYSVIGNPYDHAEHPPYASEEVSNERFAEAAAVADIVF
                     LDEAKPACSAKLAELTELPDGAVPYVLESGEGDRLLTGDQLHRIVAAQKNTDGQFIVVS
                     SEGPKGDRIVDHYHEYHTETFYCLEGQMTMWTDGQEIQLNPGDFLHVPANTVHSYRLDS
                     HYTKMVGVLVPGLFEPFFRTLGDPYEGHIFPCEPQALRFDRILQNIEALDLKVMKP"
     CDS             complement(10032..10607)
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 63.1; E-value: 7.5e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg16_11"
                     /transl_table=11
                     /translation="MTSRGDSREKILHTASRLFQLQGYHATGLNQIVKESGAPKGSLYH
                     FFPNGKEELAIEAVTYTGKIVEHLIQQSMDESSDPVEAIQLFIKKTASQFDNTESIKGI
                     PVGLLASETALISEPLRTVCMKVFKSWEAVFARKLMENGFAEEEANQLGTLINSMIEGG
                     IMLSLTNKDKTPLLLIAEQIPVLVRKKG"
ORIGIN
        1 ttgcgccgcg ctgtagcagc tggcggtcat taatcttatc caaaacgatt aacgtttgag
       61 gctatcacgc caacttgata aggaggatgc tgaagatgat tacggctgaa gaatgcagaa
      121 cgtacaaaga atttgttgat ctttaccaat cctatcttta ccccttgctt ggcgccagac
      181 tgtcccggat gtattccccc aaaaacaaag tcattatcga tatgggcaca ggtccaggtt
      241 atttaagcat tcagttggct aaaagaacaa atgcgcacgt gcatgctgtc gatattaacc
      301 cggccatgca tgaaatcgct caagaagaag ctaaaaaaag cggagtaagc agcctgattt
      361 catttgattt ggaagatgtc caccatttat cttacgctga ccaatatgct gacttcatcg
      421 tctcctactc ttgcctgcat cattgggaag acgttgttaa aggacttaaa gagtgctata
      481 gagttctggc tccgggcgga aaaattgtca ttttggatac atttaatccc caaggaagcc
      541 atttagagat tatgcgaaaa caaatcaaag aaccggaata cttcaggttt gtaagagagg
      601 catttgaaga aagttattcc tttgaagaca ttcaccagtt tgttcaggat gccggcattc
      661 ccaattattc attagaaacc tttcactttt taccggagga ttttatagaa agcttagatg
      721 agctggagga tgctcccctg tgggaacaaa atgatcaaag tactgatcat gaaattgagt
      781 ctgtcacatg gatgttaacg atagaaaaag aaaaggaagg tgcattgtaa tgatcaatga
      841 atcaactgtt ttatccaaaa atccagaaat gccatcaaga aaatatttga aaagcattat
      901 tatagagccg ggcatcactt taaatgaaat ggcatcagat atttataacc atatcgacgg
      961 caaggtcagc atacatgata tttgctcaaa aatcgtcaat gaatatgatg ttgattatca
     1021 aacctgctta gaagattgta tggagctgtt tgagttgctt attgatcatg aagcaatcaa
     1081 agttaagcag ggggcatgag aattggaaaa acaaaaagtg cttgctttac cagacgatgt
     1141 acatgagctg agtacacacc gttctaaatc aatcgtaaat tacatcatca ctctgcttgc
     1201 ctttgccaaa aaacaaggat tgactcatca agatattgta agctggattc acgagcaata
     1261 tgaggaaaga ggatattatg atgagtggag acacattaac agccaacaac cagttggatc
     1321 atttgtggaa ctctttataa aaggaagacg tttactttat gacaaaattg aattgtttga
     1381 aacagaagat aaatatgtcg taaataccca cacttggtat gaaaaagaac ctagtgaggc
     1441 ctttttttat tttgaaattg atcccgaaga attttctgcg tacgcttcca ttctcgcaat
     1501 cgaaaacgca aaacgtctcg gaattaaaat cgatattgta aaagaaacag atgtagagac
     1561 agcttatatc tataaacatc aataacgcta ttgggaggga gacatatgtg cgggctcgcg
     1621 ggtattataa atctggctgc tccccgttct caggaatgta cctttcatat attgaaaggc
     1681 atggcagatg ccatcagcta taggggaccg gatgatgaac aatatcatat tgattccaaa
     1741 gtcggctttg catttcggcg attgtccatt cttgaccttg taaatggaca gcagcccttt
     1801 ttaaatgagg atggatcaat cgtcgttatg gtaaatggag aaatttataa ctataaagaa
     1861 ctgaaggctt ctttacacaa tcatatgttt aaaacgacat ctgattgtga agtaattgtt
     1921 catttatatg aagaaaaagg gattggattt gtagacgaca tcatcggaat gttttcaata
     1981 gccatttggg acaaaaataa aaacaaagta tttttagttc gtgaccgctt tgggattaaa
     2041 ccgctttttt acacagagct aaaacacgag cttatatttg cctctgaaat aaaatcccta
     2101 ttttctcatc ctcactgtcc ccgccaattt aattggaaag aagcactctc agacatttgg
     2161 ctaagcgggg aagcagccag taatcataaa gaaaccactt ccttttttgt aaacatccaa
     2221 aatctcgatg ctggccatta tctcgaaatt aatttgacaa caaatgaacg aaaaacagca
     2281 agctattggt ctttacagga tattttgctc aggcaaggct atcgtgagaa tctccatccc
     2341 gatgacctga ttgaaggata tagagaactg ctggcagatt cagtccatag atgtttacaa
     2401 agcgacgttg aagtcgggtt gtttcttagc ggtggcattg attcagctgc agtcgcacat
     2461 tttgctgcag aaaaacagga tctccatacg tttacagtat taagccaaag tacatttaca
     2521 aatgaagatg caaaatatgc ccattggctg gctaaagatt tacaccttcc aaatcatcag
     2581 gttctctatc aattagggaa cgatgagtta ttacaaccag agtcatataa acatttgtta
     2641 tggatctgtg aaacaccgtt ttgcggaccg gaacaattat ataagtttca tttacataag
     2701 tatgccaaag cgataaggcc aaacctgaaa gtcatgctga ccggccaggg cagcgacgaa
     2761 tttaacggcg gttacagcac gacactttca ccagccgaga acccaagttg ggaaggattt
     2821 attgaatcgg tcaatacgat ggagatgaac cggctgcatc ggctgcaggg aaatatcttt
     2881 agagtgtggg aggagcattt tggactttct cctataaacc tttcttattt aaagagcaat
     2941 gattccagcc aagcagatcc ttggcaatcg tatgtcctga caaaataccg tgatctgcaa
     3001 atgtataatt gctggcatga agatcggatc gccgcggcta atcatatcga aaaccgtgta
     3061 ccgttcttgg accatcggct tgttgaatgg gtttgcggaa tacctgatgg actccgtaaa
     3121 gacttgttat gggataagtc ggtattgcga aaatcattaa caaatgagct gcatacaagc
     3181 tatacccacc ggccaaaggt tccttttttc tatggtaagg acgtgagata tacacataaa
     3241 atgatgtttc atcttctgaa gaaaaacaat tatcagctta tagaggaggc cttctctcac
     3301 agcgatgcct ccagcataat acaggttgaa cacattcatg ccatcatgac atatttggag
     3361 gatgatcctg agtttacaaa ttttgaattt ttattaagac tggtgaacat gggactttta
     3421 tcaaaaatga ctaaagaaac cccttctgtt caattagaca taaccagcca tttagaatcg
     3481 ataacaataa aagactggca ctcacaggaa ggtgatattg ccagtcgttt aaatatctca
     3541 gccaataagt gtgaaggaca agatattttg gcgctaaacc ctggcgtcac tctgttaagg
     3601 ccggaaagcg atagtgagca ttgcatctac attgcggaag aaggatttat tcagtttatt
     3661 gtttcggagg aagacgtcgg agcttggctg catattctct gcgatattaa tggaaaagac
     3721 acacttcata cgattttaga cagacatggt gtcagccttg aagaagtggc caaatatatt
     3781 caagaagcca tcgaacacaa tatcattttg atcaaacaaa aaaatctgcc agaaggagca
     3841 tatagatgag catcttttat tcgttttccg cacttagggg attagcaatg gggatttttt
     3901 cgcctatttg gattctttat ctgatatcta aagattatga tttccttcag attggattaa
     3961 tgggagcggt acttgaaatt gctaagctta tatttgaagt tccttccggc gtttttgctg
     4021 atcgttatgg aattaaaatt tcaattgcca gttcattctt tttctccatc cttacatggg
     4081 ccttcttccc ttttatcgat tcagctgcta tttgcatact ggctatgatc atatgggctt
     4141 tatcagattc cttaatttcc ggttcttttg aaacttggat gagccgtgtc gcaggggaag
     4201 atcgattcgg caaagaaatg atgaaaaaca cacaattgct aatcactttt ttaattattg
     4261 gaagtattgc cagcgggtat ttgtattcat taaatatcta ttttcctttc ctgctcgtta
     4321 tggtgatcta cttattacta tttatttgga tgtctgtatt tattaaagtc ccttctgttt
     4381 ccgaaacaaa tcatggggat cagaaccaac atgattcgat aaagattatc aaagaaagtt
     4441 taaaaattat ctttaacaaa aaaagggttc ttttaatcgt catagccggt ttctttacag
     4501 ccacagccta tgacacaatt tcccgttact ggcagccttt tttgagtgat ttaggctttt
     4561 cagaaaagtc actgggatat atttttgccc taggagggtt taccgctctc gttcttttga
     4621 cattaaccat caggttcgaa aagaagatcg aaaaaaatcc atatctcgct ttaacctcat
     4681 tggattccat gggcatggtc atgacttttc tattgtctag agcattcagg ccgctgggca
     4741 ttccatgtac agcgtttttg cttgcaattg aagatattca tcatccgatc gtaacaagtt
     4801 acttaaataa gtttttcccc gattcataca agaacacact tttctcgtta aactcagggg
     4861 taggagcaat tggagaaatt ctttccggtg tcattttcgg catcatttcc gcagcctttg
     4921 ggctctctgc catgtttgtt gttgtagctg tatttctatt aatccctatt atcctttata
     4981 cgatagtgcc taagattaaa gacaatgata tgaaagttca gattgaaaaa tcccagcaag
     5041 tgtaaatgtt ttgtatcaca gtaagaagac cttcttatta aaagaaggtc ttctgctatt
     5101 ctattcagtt atttcccaaa agccatcagc ttcgtataac ttccaatata aagtgttccg
     5161 tcctcagcga gctgaggaga agacacgacg ttgctgtcgg tttgatagct ccataattca
     5221 ttgccgtttg cgtctgccgc ataaaccttc atatcatctg acccgaaata aaccgttccc
     5281 ttcgcgtcaa tcagcggcgc cgttctgaca gggccgtctg tgtagaatga ccagttcata
     5341 tccccgtttt tgctgatgga aaacagctcg ccgcttcctg agccgatgta gatattgcca
     5401 ttatgatcaa tcgcaggaga tgagctggag aacccgttta gcgggaatgt ccatttcaaa
     5461 ctgcctgttg atgtataagc atacagctgt ccatcttggt tgccggcata aatgtttccg
     5521 tccttatcaa tcaccggata tcctttaaac gcatttgacg tcgttctgga ccatttcacc
     5581 tgtccggttc cggagttgat cgcataaaac acgtaattat atgtgccgac atacacggtg
     5641 ccgtttttgg caagcaccgg cacagagctg acgaccccat ttgttttcaa cttccagcgc
     5701 tctgtccagg ttgattttga cgtcggtttg atcgcgtgaa cataattatc aagtgttgag
     5761 aaatacaacg tcccgtctga accgatcacc gtttcagagc ttggcccgcc gcttaacgga
     5821 accgttgtta aaatttctcc cgtttctttg tcaataaaat aaatcttttt gtcataggat
     5881 gccaaataga taacgccgtt ggtcccaagt acaggagatt gcgtatatgt ttttccaaga
     5941 ttgcccgtca cccatttgac tgagccgtct ggattaaagg ctttcatttc cccgtctctg
     6001 gaatgaagat atactgtgcc gtctccgtca atcacagccc ccgctccatt ttgcggagtc
     6061 gttctgatgt cgttttgcca tttcagcgtc ccgtctgtat ttccggcgaa ccggctttcg
     6121 cgtgaccagt taaacatggc aggcgccatc gcttgtacat catatcttcc tggcaaaaag
     6181 ccagatgctc cattattttg agaaaacacc gtttccgccg cataagcagc tgtcggctga
     6241 agcactttgg cagcgggcac atcagaaaca gcgccggccg aaacagccgc cgccaccgca
     6301 gctcccgcaa tcaaagcttt catacgaaat gacttgacca tcattgagac ccccattata
     6361 tgtaacttct aatttgtgac catcataaca tattcatcca ttttataaat ctatttcaca
     6421 aaaacatcac aaactagaaa actatgtaag agtattcacg gacgtttttt cagcacccga
     6481 tcgaaatgca gccacaaacc aaatgacgtt gacagcagcc gcagcgagac taactcccaa
     6541 aacaaagatc acctcagaaa gcagatggtc actaaagaaa ctaaacatca agataaaacc
     6601 ggccgaagac aaatgaatca aaagcccgaa gccgcaaagc accgccatga catacctcat
     6661 tgcatcgact ccgagcatat aaacgagaaa tggaatgaaa tacaagacaa ggatcatacc
     6721 gacagctgac cacatgccag ctgaattaaa ctgattggcc gccgctcccg ttccggccag
     6781 cggcgaaagt gaagccgcca caatcacggc gcaaaaaaga aacgcagaaa tggttgtcat
     6841 gatcgccacg ctattttttt ttgacatcaa actcctcctt taatagaaat attaaccttt
     6901 tttattataa gtaagttgaa tgttatattc attatatttt taaaaaattc cagaatacat
     6961 acacaaatgc tatgcttctt tctagtatat ttatatagta aaaaacaaag gataaaagac
     7021 tcatttttct gtaatatcag gattttatca ccataccata ttgcatgtac atgtttttca
     7081 aagtatacta ttccagatta attcagagga gagagaaaaa tacatggaaa aaccagcagg
     7141 attttggatt cgttttttag cttattttat tgacggcatt attgtatctg ttcctagtta
     7201 tattattcta tttattatca attctgtgtt tgtagctggg gctgtggcaa caaaccctta
     7261 catgacggaa gaagagtatt tagtgaaata catgacgctt gcatttttgc ctactatgct
     7321 gatcatgatc gtcatcagcg tgttatatta cgggctgctc acagcttcta aaatgcaagg
     7381 cacacttggc aaaaaaattc ttggcctgaa agtggtcaat gaacaaggtg aacgggtttc
     7441 tgtcggacag ggaattggcc gttactttgc ctatatctta tctggaatca tcttttatat
     7501 cgggtttatc atgatcgcct ttggagagaa aaaaggcctg catgacatca tttgcaaaac
     7561 acgtgtcgtg tataaataat agaaaaaagt ctagacgcca ataggcatct agacttttgt
     7621 tttctttgca ataggctgcc acgacagata cgtagcgctt ctccacaacc actcaaacgg
     7681 ccccatccga aagacacgaa gccaaaggtg gctgaagacc atttgaacgg cacaaacagc
     7741 aattgtaatg agcacaccgg cagcagggta cacttttcca tacaggccca agccgtaatg
     7801 ataaaaaatc caagtacaca caatagactg catcaaataa ttggtaaatg ccatcctccc
     7861 aacagcggag aatgattgca gcactgttct cactcttgtt ttatgataaa gatagacaac
     7921 cgttgtaaca tagaaaaaca tgaggaaagg cgcgccaatc agcaaacata tttctttatc
     7981 cgttacactg tacagcacct gggcgccgat gccgatgaca agcccagcca tccataatcg
     8041 ttttaatcct ttgcgatgct tttccggttc atgcaaatac cgtgattttg ctgccgcagc
     8101 tcccagcaaa aacatgctga aatatggaat ggatgcaaag aagtagttga gcggattata
     8161 cgtaagcatg ccattcgaag acatgtaaac aagacggtcg tggatccgct gttctgcaat
     8221 atccttcagg ctgccgcttc cataaacatg aatcgcttgt tttgcctgct gtgttaccgc
     8281 ttgtacccat tcctgtccgt ttgattgatc aaaacttgtc aacatgaacg gaatggaaaa
     8341 cagaagatac aaagagaccg cccatatcag cagtgttttc ggctttgctt ttcgaaacaa
     8401 gagcaggaca aatccgagca gggcatattc tgttaaaata tccccgtccc atatcaaaaa
     8461 ggcatgaatc gttccaaaca agagaagcgc cattaacctt ctcacatata acggaacaaa
     8521 ccgtttccct ttgttttctg ctctctccat catgacaacc atgccaaatc caaataaaaa
     8581 ggaaaacaat aaaatacatt ttgtttgaat gaagaatttc agtatgtctg cggcggcaaa
     8641 atcagcttca gaccacttat ccatgaaaaa attctctttt ccaagcatag acaaatacat
     8701 atccggataa ctgaaatgtg ccagattgac aaataagatg ccgaaaatcg ccattcctct
     8761 cagcacatca agcacaccga tccgctcatt tgttaaagtc ggctgtaatg aagacatagc
     8821 catcacgctc cttttttctg taccttaagg gtaggaaaaa atgaagcgcg gtaacatcga
     8881 tttaggtgtc aggccggcat gaaaacctta caatcttgtc atctttatgg tttcatcacc
     8941 tttaaatcta atgcttcgat attctgcaaa atgcgatcaa agcgcaaagc ctgaggctca
     9001 catgggaaga tgtggccttc atacgggtcg cctaacgtcc ggaaaaacgg ttcaaataaa
     9061 ccaggaacca atacgcccac catctttgta tagtgagaat caaggcgata ggagtgaacg
     9121 gtatttgcag ggacatgcag gaaatctccc ggattcagct gaatttcctg gccatctgtc
     9181 cacatcgtca tctggccttc aaggcaataa aatgtttctg tatgatattc atggtagtga
     9241 tcaacgattc ggtcaccttt agggccttca gatgatacga cgataaactg gccatctgta
     9301 tttttttgtg cagccacaat gcggtgaagc tgatctccag tcaacagacg atctccttct
     9361 ccagattcaa gaacgtatgg aaccgctcca tctggcagct ctgtaagttc cgctaatttg
     9421 gccgaacatg caggctttgc ttcatctaga aatacaatgt ccgctacagc ggctgcttct
     9481 gcaaatcgct cgtttgagac ttcttcgctt gcgtacggcg gatgttcagc gtgatcatac
     9541 ggattcccaa taacggaata caagtgcgct acgtttcctt tcatcgtgta agacaccagt
     9601 cttgttctgt ggctctgcat ccggtagctg tgcggtgttc ccgccggaat gttggcataa
     9661 tcacctgata ttaataaata gcgttcacca tcaagtgtca gttccagttt cccgtccaaa
     9721 acgagaattc cttcatgtgt gtccttgtgg acgtgaagcg gaaaggcatc tccttttccc
     9781 ccggaaagaa gcacgatctc aaacaaatca cctgtgctcc tcccattcgc catcaccgtg
     9841 gcaacctgtc tgccgaacag atagcgctcg ccttctccgc tccggagcaa ataaggcatt
     9901 ttttctttag gcaatgaatg tgtacataat gttttcatat tatcgcttcc tccaatttag
     9961 accagtctat atattatcat tcatttgtct agaccgttct atataattgt aggagaaagg
    10021 ataacaaaat gctacccttt ttttctcacc agcactggta tttgttcggc aatgagaaga
    10081 agaggcgttt tgtctttatt cgttaacgaa agcatgatgc cgccctcaat catcgaatta
    10141 atcagcgttc caagctgatt tgcttcttct tctgcaaatc cgttttccat taattttctg
    10201 gcaaaaaccg cttcccagct tttaaacacc ttcatgcaaa ccgtccgcag cggttcactg
    10261 attaacgctg tctcactcgc cagcaaaccg actggaatac ctttaatgct ttctgtgttg
    10321 tcaaattggc tggctgtttt tttgataaaa agctgaatcg cttcaacagg atcagaggat
    10381 tcatccatgc tttgctgtat cagatgttca acgatcttac ctgtatatgt aaccgcttca
    10441 attgctagtt cttctttgcc attcggaaaa aagtgataaa gcgatccttt tggagcaccg
    10501 ctttctttta caatctggtt caaacctgtc gcgtgatatc cttgcagctg gaacagacgt
    10561 gacgccgtgt gaaggatttt ttcacgtgaa tctcctctgc tagtcattaa aacattccct
    10621 cctaggtatg gtagagcgac ttatataata taaaaaagaa ccctgtgatt gtcaaaaggg
    10681 gtaagaccct tccggatggg gtaatgtaca aaaacagcgt ctaggaggga tctctcaatg
    10741 acaatcgatc attcagtcac aaatacagag cagcttgaac aacagaaccc cgccataaaa
    10801 acaaagctca aactgaaaaa gcttaaggat caggtgatcg tcattaccgg cgcttcaagc
    10861 ggtatcggac ttgtcacggc gagaatggca gctgaaaaag gcgcaaaggt cgtggcagca
    10921 gcgcgaaatg aagaggcgct gaaggagctc actgatgaac ttaaggaaaa agggcacgac
    10981 gccatatggg taaaggcgga tgtcggaaaa gaagaggacg tcaaccgcat cgcagaaacc
    11041 gcgatcagca cattcggccg ctttgataca tgggtcaaca atgcggccgt ctcgacttt
//
