LOCUS       c00050_JADOXT0..       11108 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JADOXT010000007.1 Bacillus subtilis strain 168(rho6) 1L9_contig_7,
            whole genome shotgun sequence.
ACCESSION   JADOXT010000007
VERSION     JADOXT010000007
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-21 01:55:16
            Original ID  :: JADOXT010000007.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11108
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11108
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[838:1108](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      839..1108
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..11108
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11108
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             105..839
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 103.3; E-value:
                     2.5e-31)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_1"
                     /transl_table=11
                     /translation="MITAEECRTYKEFVDLYQSYLYPLLGARLSRMYSPKNKVIIDMGT
                     GPGYLSIQLAKRTNAHVHAVDINPAMHEIAQEEAKKSGVSSLISFDLEDVHHLSYADQY
                     ADFIVSYSCLHHWEDVVKGLKECYRVLAPGGKIVILDTFNPQGSHLEIMRKQIKEPEYF
                     RFVREAFEESYSFEDIHQFVQDAGIPNYSLETFHFLPEDFIESLDELEDAPLWEQNDQS
                     TDHEIESVTWMLTIEKEKEGAL"
     CDS             839..1108
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_2"
                     /sec_met_domain="PF05402 (E-value: 1.9e-12, bitscore: 40.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.8e-09,
                     bitscore: 30.6, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 1.7e-09, bitscore:
                     30.4, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINESTVLSKNPEMPSRKYLKSIIIEPGITLNEMASDIYNHIDGK
                     VSIHDICSKIVNEYDVDYQTCLEDCMELFELLIDHEAIKVKQGA"
     CDS             1112..1594
                     /locus_tag="ctg50_3"
                     /transl_table=11
                     /translation="LEKQKVLALPDDVHELSTHRSKSIVNYIITLLAFAKKQGLTHQDI
                     VSWIHEQYEERGYYDEWRHINSQQPVGSFVELFIKGRRLLYDKIELFETEDKYVVNTHT
                     WYEKEPSEAFFYFEIDPEEFSAYASILAIENAKRLGIKIDIVKETDVETAYIYKHQ"
     CDS             1615..3858
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 407.1; E-value: 2.2e-123)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_4"
                     /sec_met_domain="Asn_synthase (E-value: 2.8e-95, bitscore:
                     312.9, seeds: 78, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 1e-44, bitscore: 144.4,
                     seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGLAGIINLAAPRSQECTFHILKGMADAISYRGPDDEQYHIDSK
                     VGFAFRRLSILDLVNGQQPFLNEDGSIVVMVNGEIYNYKELKASLHNHMFKTTSDCEVI
                     VHLYEEKGIGFVDDIIGMFSIAIWDKNKNKVFLVRDRFGIKPLFYTELKHELIFASEIK
                     SLFSHPHCPRQFNWKEALSDIWLSGEAASNHKETTSFFVNIQNLDAGHYLEINLTTNER
                     KTASYWSLQDILLRQGYRENLHPDDLIEGYRELLADSVHRCLQSDVEVGLFLSGGIDSA
                     AVAHFAAEKQDLHTFTVLSQSTFTNEDAKYAHWLAKDLHLPNHQVLYQLGNDELLQPES
                     YKHLLWICETPFCGPEQLYKFHLHKYAKAIRPNLKVMLTGQGSDEFNGGYSTTLSPAEN
                     PSWEGFIESVNTMEMNRLHRLQGNIFRVWEEHFGLSPINLSYLKSNDSSQADPWQSYVL
                     TKYRDLQMYNCWHEDRIAAANHIENRVPFLDHRLVEWVCGIPDGLRKDLLWDKSVLRKS
                     LTNELHTSYTHRPKVPFFYGKDVRYTHKMMFHLLKKNNYQLIEEAFSHSDASSIIQVEH
                     IHAIMTYLEDDPEFTNFEFLLRLVNMGLLSKMTKETPSVQLDITSHLESITIKDWHSQE
                     GDIASRLNISANKCEGQDILALNPGVTLLRPESDSEHCIYIAEEGFIQFIVSEEDVGAW
                     LHILCDINGKDTLHTILDRHGVSLEEVAKYIQEAIEHNIILIKQKNLPEGAYR"
     CDS             3855..5054
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 97.4; E-value: 1.1e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg50_5"
                     /transl_table=11
                     /translation="MSIFYSFSALRGLAMGIFSPIWILYLISKDYDFLQIGLMGAVLEI
                     AKLIFEVPSGVFADRYGIKISIASSFFFSILTWAFFPFIDSAAICILAMIIWALSDSLI
                     SGSFETWMSRVAGEDRFGKEMMKNTQLLITFLIIGSIASGYLYSLNIYFPFLLVMVIYL
                     LLFIWMSVFIKVPSVSETNHGDQNQHDSIKIIKESLKIIFNKKRVLLIVIAGFFTATAY
                     DTISRYWQPFLSDLGFSEKSLGYIFALGGFTALVLLTLTIRFEKKIEKNPYLALTSLDS
                     MGMVMTFLLSRAFRPLGIPCTAFLLAIEDIHHPIVTSYLNKFFPDSYKNTLFSLNSGVG
                     AIGEILSGVIFGIISAAFGLSAMFVVVAVFLLIPIILYTIVPKIKDNDMKVQIEKSQQV
                     "
     CDS             complement(5118..6350)
                     /locus_tag="ctg50_6"
                     /transl_table=11
                     /translation="MVKSFRMKALIAGAAVAAAVSAGAVSDVPAAKVLQPTAAYAAETV
                     FSQNNGASGFLPGRYDVQAMAPAMFNWSRESRFAGNTDGTLKWQNDIRTTPQNGAGAVI
                     DGDGTVYLHSRDGEMKAFNPDGSVKWVTGNLGKTYTQSPVLGTNGVIYLASYDKKIYFI
                     DKETGEILTTVPLSGGPSSETVIGSDGTLYFSTLDNYVHAIKPTSKSTWTERWKLKTNG
                     VVSSVPVLAKNGTVYVGTYNYVFYAINSGTGQVKWSRTTSNAFKGYPVIDKDGNIYAGN
                     QDGQLYAYTSTGSLKWTFPLNGFSSSSPAIDHNGNIYIGSGSGELFSISKNGDMNWSFY
                     TDGPVRTAPLIDAKGTVYFGSDDMKVYAADANGNELWSYQTDSNVVSSPQLAEDGTLYI
                     GSYTKLMAFGK"
     CDS             complement(6451..6876)
                     /locus_tag="ctg50_7"
                     /transl_table=11
                     /translation="MSKKNSVAIMTTISAFLFCAVIVAASLSPLAGTGAAANQFNSAGM
                     WSAVGMILVLYFIPFLVYMLGVDAMRYVMAVLCGFGLLIHLSSAGFILMFSFFSDHLLS
                     EVIFVLGVSLAAAAVNVIWFVAAFRSGAEKTSVNTLT"
     CDS             7133..7588
                     /locus_tag="ctg50_8"
                     /transl_table=11
                     /translation="MEKPAGFWIRFLAYFIDGIIVSVPSYIILFIINSVFVAGAVATNP
                     YMTEEEYLVKYMTLAFLPTMLIMIVISVLYYGLLTASKMQGTLGKKILGLKVVNEQGER
                     VSVGQGIGRYFAYILSGIIFYIGFIMIAFGEKKGLHDIICKTRVVYK"
     CDS             complement(7618..8826)
                     /locus_tag="ctg50_9"
                     /transl_table=11
                     /translation="MSSLQPTLTNERIGVLDVLRGMAIFGILFVNLAHFSYPDMYLSML
                     GKENFFMDKWSEADFAAADILKFFIQTKCILLFSFLFGFGMVVMMERAENKGKRFVPLY
                     VRRLMALLLFGTIHAFLIWDGDILTEYALLGFVLLLFRKAKPKTLLIWAVSLYLLFSIP
                     FMLTSFDQSNGQEWVQAVTQQAKQAIHVYGSGSLKDIAEQRIHDRLVYMSSNGMLTYNP
                     LNYFFASIPYFSMFLLGAAAAKSRYLHEPEKHRKGLKRLWMAGLVIGIGAQVLYSVTDK
                     EICLLIGAPFLMFFYVTTVVYLYHKTRVRTVLQSFSAVGRMAFTNYLMQSIVCTWIFYH
                     YGLGLYGKVYPAAGVLITIAVCAVQMVFSHLWLRVFRMGPFEWLWRSATYLSWQPIAKK
                     TKV"
     CDS             complement(8934..9947)
                     /locus_tag="ctg50_10"
                     /transl_table=11
                     /translation="MKTLCTHSLPKEKMPYLLRSGEGERYLFGRQVATVMANGRSTGDL
                     FEIVLLSGGKGDAFPLHVHKDTHEGILVLDGKLELTLDGERYLLISGDYANIPAGTPHS
                     YRMQSHRTRLVSYTMKGNVAHLYSVIGNPYDHAEHPPYASEEVSNERFAEAAAVADIVF
                     LDEAKPACSAKLAELTELPDGAVPYVLESGEGDRLLTGDQLHRIVAAQKNTDGQFIVVS
                     SEGPKGDRIVDHYHEYHTETFYCLEGQMTMWTDGQEIQLNPGDFLHVPANTVHSYRLDS
                     HYTKMVGVLVPGLFEPFFRTLGDPYEGHIFPCEPQALRFDRILQNIEALDLKVMKP"
     CDS             complement(10041..10616)
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 63.1; E-value: 7.5e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg50_11"
                     /transl_table=11
                     /translation="MTSRGDSREKILHTASRLFQLQGYHATGLNQIVKESGAPKGSLYH
                     FFPNGKEELAIEAVTYTGKIVEHLIQQSMDESSDPVEAIQLFIKKTASQFDNTESIKGI
                     PVGLLASETALISEPLRTVCMKVFKSWEAVFARKLMENGFAEEEANQLGTLINSMIEGG
                     IMLSLTNKDKTPLLLIAEQIPVLVRKKG"
ORIGIN
        1 ctttttgaat tgcgccgcgc tgtagcagct ggcggtcatt aatcttatcc aaaacgatta
       61 acgtttgagg ctatcacgcc aacttgataa ggaggatgct gaagatgatt acggctgaag
      121 aatgcagaac gtacaaagaa tttgttgatc tttaccaatc ctatctttac cccttgcttg
      181 gcgccagact gtcccggatg tattccccca aaaacaaagt cattatcgat atgggcacag
      241 gtccaggtta tttaagcatt cagttggcta aaagaacaaa tgcgcacgtg catgctgtcg
      301 atattaaccc ggccatgcat gaaatcgctc aagaagaagc taaaaaaagc ggagtaagca
      361 gcctgatttc atttgatttg gaagatgtcc accatttatc ttacgctgac caatatgctg
      421 acttcatcgt ctcctactct tgcctgcatc attgggaaga cgttgttaaa ggacttaaag
      481 agtgctatag agttctggct ccgggcggaa aaattgtcat tttggataca tttaatcccc
      541 aaggaagcca tttagagatt atgcgaaaac aaatcaaaga accggaatac ttcaggtttg
      601 taagagaggc atttgaagaa agttattcct ttgaagacat tcaccagttt gttcaggatg
      661 ccggcattcc caattattca ttagaaacct ttcacttttt accggaggat tttatagaaa
      721 gcttagatga gctggaggat gctcccctgt gggaacaaaa tgatcaaagt actgatcatg
      781 aaattgagtc tgtcacatgg atgttaacga tagaaaaaga aaaggaaggt gcattgtaat
      841 gatcaatgaa tcaactgttt tatccaaaaa tccagaaatg ccatcaagaa aatatttgaa
      901 aagcattatt atagagccgg gcatcacttt aaatgaaatg gcatcagata tttataacca
      961 tatcgacggc aaggtcagca tacatgatat ttgctcaaaa atcgtcaatg aatatgatgt
     1021 tgattatcaa acctgcttag aagattgtat ggagctgttt gagttgctta ttgatcatga
     1081 agcaatcaaa gttaagcagg gggcatgaga attggaaaaa caaaaagtgc ttgctttacc
     1141 agacgatgta catgagctga gtacacaccg ttctaaatca atcgtaaatt acatcatcac
     1201 tctgcttgcc tttgccaaaa aacaaggatt gactcatcaa gatattgtaa gctggattca
     1261 cgagcaatat gaggaaagag gatattatga tgagtggaga cacattaaca gccaacaacc
     1321 agttggatca tttgtggaac tctttataaa aggaagacgt ttactttatg acaaaattga
     1381 attgtttgaa acagaagata aatatgtcgt aaatacccac acttggtatg aaaaagaacc
     1441 tagtgaggcc tttttttatt ttgaaattga tcccgaagaa ttttctgcgt acgcttccat
     1501 tctcgcaatc gaaaacgcaa aacgtctcgg aattaaaatc gatattgtaa aagaaacaga
     1561 tgtagagaca gcttatatct ataaacatca ataacgctat tgggagggag acatatgtgc
     1621 gggctcgcgg gtattataaa tctggctgct ccccgttctc aggaatgtac ctttcatata
     1681 ttgaaaggca tggcagatgc catcagctat aggggaccgg atgatgaaca atatcatatt
     1741 gattccaaag tcggctttgc atttcggcga ttgtccattc ttgaccttgt aaatggacag
     1801 cagccctttt taaatgagga tggatcaatc gtcgttatgg taaatggaga aatttataac
     1861 tataaagaac tgaaggcttc tttacacaat catatgttta aaacgacatc tgattgtgaa
     1921 gtaattgttc atttatatga agaaaaaggg attggatttg tagacgacat catcggaatg
     1981 ttttcaatag ccatttggga caaaaataaa aacaaagtat ttttagttcg tgaccgcttt
     2041 gggattaaac cgctttttta cacagagcta aaacacgagc ttatatttgc ctctgaaata
     2101 aaatccctat tttctcatcc tcactgtccc cgccaattta attggaaaga agcactctca
     2161 gacatttggc taagcgggga agcagccagt aatcataaag aaaccacttc cttttttgta
     2221 aacatccaaa atctcgatgc tggccattat ctcgaaatta atttgacaac aaatgaacga
     2281 aaaacagcaa gctattggtc tttacaggat attttgctca ggcaaggcta tcgtgagaat
     2341 ctccatcccg atgacctgat tgaaggatat agagaactgc tggcagattc agtccataga
     2401 tgtttacaaa gcgacgttga agtcgggttg tttcttagcg gtggcattga ttcagctgca
     2461 gtcgcacatt ttgctgcaga aaaacaggat ctccatacgt ttacagtatt aagccaaagt
     2521 acatttacaa atgaagatgc aaaatatgcc cattggctgg ctaaagattt acaccttcca
     2581 aatcatcagg ttctctatca attagggaac gatgagttat tacaaccaga gtcatataaa
     2641 catttgttat ggatctgtga aacaccgttt tgcggaccgg aacaattata taagtttcat
     2701 ttacataagt atgccaaagc gataaggcca aacctgaaag tcatgctgac cggccagggc
     2761 agcgacgaat ttaacggcgg ttacagcacg acactttcac cagccgagaa cccaagttgg
     2821 gaaggattta ttgaatcggt caatacgatg gagatgaacc ggctgcatcg gctgcaggga
     2881 aatatcttta gagtgtggga ggagcatttt ggactttctc ctataaacct ttcttattta
     2941 aagagcaatg attccagcca agcagatcct tggcaatcgt atgtcctgac aaaataccgt
     3001 gatctgcaaa tgtataattg ctggcatgaa gatcggatcg ccgcggctaa tcatatcgaa
     3061 aaccgtgtac cgttcttgga ccatcggctt gttgaatggg tttgcggaat acctgatgga
     3121 ctccgtaaag acttgttatg ggataagtcg gtattgcgaa aatcattaac aaatgagctg
     3181 catacaagct atacccaccg gccaaaggtt ccttttttct atggtaagga cgtgagatat
     3241 acacataaaa tgatgtttca tcttctgaag aaaaacaatt atcagcttat agaggaggcc
     3301 ttctctcaca gcgatgcctc cagcataata caggttgaac acattcatgc catcatgaca
     3361 tatttggagg atgatcctga gtttacaaat tttgaatttt tattaagact ggtgaacatg
     3421 ggacttttat caaaaatgac taaagaaacc ccttctgttc aattagacat aaccagccat
     3481 ttagaatcga taacaataaa agactggcac tcacaggaag gtgatattgc cagtcgttta
     3541 aatatctcag ccaataagtg tgaaggacaa gatattttgg cgctaaaccc tggcgtcact
     3601 ctgttaaggc cggaaagcga tagtgagcat tgcatctaca ttgcggaaga aggatttatt
     3661 cagtttattg tttcggagga agacgtcgga gcttggctgc atattctctg cgatattaat
     3721 ggaaaagaca cacttcatac gattttagac agacatggtg tcagccttga agaagtggcc
     3781 aaatatattc aagaagccat cgaacacaat atcattttga tcaaacaaaa aaatctgcca
     3841 gaaggagcat atagatgagc atcttttatt cgttttccgc acttagggga ttagcaatgg
     3901 ggattttttc gcctatttgg attctttatc tgatatctaa agattatgat ttccttcaga
     3961 ttggattaat gggagcggta cttgaaattg ctaagcttat atttgaagtt ccttccggcg
     4021 tttttgctga tcgttatgga attaaaattt caattgccag ttcattcttt ttctccatcc
     4081 ttacatgggc cttcttccct tttatcgatt cagctgctat ttgcatactg gctatgatca
     4141 tatgggcttt atcagattcc ttaatttccg gttcttttga aacttggatg agccgtgtcg
     4201 caggggaaga tcgattcggc aaagaaatga tgaaaaacac acaattgcta atcacttttt
     4261 taattattgg aagtattgcc agcgggtatt tgtattcatt aaatatctat tttcctttcc
     4321 tgctcgttat ggtgatctac ttattactat ttatttggat gtctgtattt attaaagtcc
     4381 cttctgtttc cgaaacaaat catggggatc agaaccaaca tgattcgata aagattatca
     4441 aagaaagttt aaaaattatc tttaacaaaa aaagggttct tttaatcgtc atagccggtt
     4501 tctttacagc cacagcctat gacacaattt cccgttactg gcagcctttt ttgagtgatt
     4561 taggcttttc agaaaagtca ctgggatata tttttgccct aggagggttt accgctctcg
     4621 ttcttttgac attaaccatc aggttcgaaa agaagatcga aaaaaatcca tatctcgctt
     4681 taacctcatt ggattccatg ggcatggtca tgacttttct attgtctaga gcattcaggc
     4741 cgctgggcat tccatgtaca gcgtttttgc ttgcaattga agatattcat catccgatcg
     4801 taacaagtta cttaaataag tttttccccg attcatacaa gaacacactt ttctcgttaa
     4861 actcaggggt aggagcaatt ggagaaattc tttccggtgt cattttcggc atcatttccg
     4921 cagcctttgg gctctctgcc atgtttgttg ttgtagctgt atttctatta atccctatta
     4981 tcctttatac gatagtgcct aagattaaag acaatgatat gaaagttcag attgaaaaat
     5041 cccagcaagt gtaaatgttt tgtatcacag taagaagacc ttcttattaa aagaaggtct
     5101 tctgctattc tattcagtta tttcccaaaa gccatcagct tcgtataact tccaatataa
     5161 agtgttccgt cctcagcgag ctgaggagaa gacacgacgt tgctgtcggt ttgatagctc
     5221 cataattcat tgccgtttgc gtctgccgca taaaccttca tatcatctga cccgaaataa
     5281 accgttccct tcgcgtcaat cagcggcgcc gttctgacag ggccgtctgt gtagaatgac
     5341 cagttcatat ccccgttttt gctgatggaa aacagctcgc cgcttcctga gccgatgtag
     5401 atattgccat tatgatcaat cgcaggagat gagctggaga acccgtttag cgggaatgtc
     5461 catttcaaac tgcctgttga tgtataagca tacagctgtc catcttggtt gccggcataa
     5521 atgtttccgt ccttatcaat caccggatat cctttaaacg catttgacgt cgttctggac
     5581 catttcacct gtccggttcc ggagttgatc gcataaaaca cgtaattata tgtgccgaca
     5641 tacacggtgc cgtttttggc aagcaccggc acagagctga cgaccccatt tgttttcaac
     5701 ttccagcgct ctgtccaggt tgattttgac gtcggtttga tcgcgtgaac ataattatca
     5761 agtgttgaga aatacaacgt cccgtctgaa ccgatcaccg tttcagagct tggcccgccg
     5821 cttaacggaa ccgttgttaa aatttctccc gtttctttgt caataaaata aatctttttg
     5881 tcataggatg ccaaatagat aacgccgttg gtcccaagta caggagattg cgtatatgtt
     5941 tttccaagat tgcccgtcac ccatttgact gagccgtctg gattaaaggc tttcatttcc
     6001 ccgtctctgg aatgaagata tactgtgccg tctccgtcaa tcacagcccc cgctccattt
     6061 tgcggagtcg ttctgatgtc gttttgccat ttcagcgtcc cgtctgtatt tccggcgaac
     6121 cggctttcgc gtgaccagtt aaacatggca ggcgccatcg cttgtacatc atatcttcct
     6181 ggcaaaaagc cagatgctcc attattttga gaaaacaccg tttccgccgc ataagcagct
     6241 gtcggctgaa gcactttggc agcgggcaca tcagaaacag cgccggccga aacagccgcc
     6301 gccaccgcag ctcccgcaat caaagctttc atacgaaatg acttgaccat cattgagacc
     6361 cccattatat gtaacttcta atttgtgacc atcataacat attcatccat tttataaatc
     6421 tatttcacaa aaacatcaca aactagaaaa ctatgtaaga gtattcacgg acgttttttc
     6481 agcacccgat cgaaatgcag ccacaaacca aatgacgttg acagcagccg cagcgagact
     6541 aactcccaaa acaaagatca cctcagaaag cagatggtca ctaaagaaac taaacatcaa
     6601 gataaaaccg gccgaagaca aatgaatcaa aagcccgaag ccgcaaagca ccgccatgac
     6661 atacctcatt gcatcgactc cgagcatata aacgagaaat ggaatgaaat acaagacaag
     6721 gatcataccg acagctgacc acatgccagc tgaattaaac tgattggccg ccgctcccgt
     6781 tccggccagc ggcgaaagtg aagccgccac aatcacggcg caaaaaagaa acgcagaaat
     6841 ggttgtcatg atcgccacgc tatttttttt tgacatcaaa ctcctccttt aatagaaata
     6901 ttaacctttt ttattataag taagttgaat gttatattca ttatattttt aaaaaattcc
     6961 agaatacata cacaaatgct atgcttcttt ctagtatatt tatatagtaa aaaacaaagg
     7021 ataaaagact catttttctg taatatcagg attttatcac cataccatat tgcatgtaca
     7081 tgtttttcaa agtatactat tccagattaa ttcagaggag agagaaaaat acatggaaaa
     7141 accagcagga ttttggattc gttttttagc ttattttatt gacggcatta ttgtatctgt
     7201 tcctagttat attattctat ttattatcaa ttctgtgttt gtagctgggg ctgtggcaac
     7261 aaacccttac atgacggaag aagagtattt agtgaaatac atgacgcttg catttttgcc
     7321 tactatgctg atcatgatcg tcatcagcgt gttatattac gggctgctca cagcttctaa
     7381 aatgcaaggc acacttggca aaaaaattct tggcctgaaa gtggtcaatg aacaaggtga
     7441 acgggtttct gtcggacagg gaattggccg ttactttgcc tatatcttat ctggaatcat
     7501 cttttatatc gggtttatca tgatcgcctt tggagagaaa aaaggcctgc atgacatcat
     7561 ttgcaaaaca cgtgtcgtgt ataaataata gaaaaaagtc tagacgccaa taggcatcta
     7621 gacttttgtt ttctttgcaa taggctgcca cgacagatac gtagcgcttc tccacaacca
     7681 ctcaaacggc cccatccgaa agacacgaag ccaaaggtgg ctgaagacca tttgaacggc
     7741 acaaacagca attgtaatga gcacaccggc agcagggtac acttttccat acaggcccaa
     7801 gccgtaatga taaaaaatcc aagtacacac aatagactgc atcaaataat tggtaaatgc
     7861 catcctccca acagcggaga atgattgcag cactgttctc actcttgttt tatgataaag
     7921 atagacaacc gttgtaacat agaaaaacat gaggaaaggc gcgccaatca gcaaacatat
     7981 ttctttatcc gttacactgt acagcacctg ggcgccgatg ccgatgacaa gcccagccat
     8041 ccataatcgt tttaatcctt tgcgatgctt ttccggttca tgcaaatacc gtgattttgc
     8101 tgccgcagct cccagcaaaa acatgctgaa atatggaatg gatgcaaaga agtagttgag
     8161 cggattatac gtaagcatgc cattcgaaga catgtaaaca agacggtcgt ggatccgctg
     8221 ttctgcaata tccttcaggc tgccgcttcc ataaacatga atcgcttgtt ttgcctgctg
     8281 tgttaccgct tgtacccatt cctgtccgtt tgattgatca aaacttgtca acatgaacgg
     8341 aatggaaaac agaagataca aagagaccgc ccatatcagc agtgttttcg gctttgcttt
     8401 tcgaaacaag agcaggacaa atccgagcag ggcatattct gttaaaatat ccccgtccca
     8461 tatcaaaaag gcatgaatcg ttccaaacaa gagaagcgcc attaaccttc tcacatataa
     8521 cggaacaaac cgtttccctt tgttttctgc tctctccatc atgacaacca tgccaaatcc
     8581 aaataaaaag gaaaacaata aaatacattt tgtttgaatg aagaatttca gtatgtctgc
     8641 ggcggcaaaa tcagcttcag accacttatc catgaaaaaa ttctcttttc caagcataga
     8701 caaatacata tccggataac tgaaatgtgc cagattgaca aataagatgc cgaaaatcgc
     8761 cattcctctc agcacatcaa gcacaccgat ccgctcattt gttaaagtcg gctgtaatga
     8821 agacatagcc atcacgctcc ttttttctgt accttaaggg taggaaaaaa tgaagcgcgg
     8881 taacatcgat ttaggtgtca ggccggcatg aaaaccttac aatcttgtca tctttatggt
     8941 ttcatcacct ttaaatctaa tgcttcgata ttctgcaaaa tgcgatcaaa gcgcaaagcc
     9001 tgaggctcac atgggaagat gtggccttca tacgggtcgc ctaacgtccg gaaaaacggt
     9061 tcaaataaac caggaaccaa tacgcccacc atctttgtat agtgagaatc aaggcgatag
     9121 gagtgaacgg tatttgcagg gacatgcagg aaatctcccg gattcagctg aatttcctgg
     9181 ccatctgtcc acatcgtcat ctggccttca aggcaataaa atgtttctgt atgatattca
     9241 tggtagtgat caacgattcg gtcaccttta gggccttcag atgatacgac gataaactgg
     9301 ccatctgtat ttttttgtgc agccacaatg cggtgaagct gatctccagt caacagacga
     9361 tctccttctc cagattcaag aacgtatgga accgctccat ctggcagctc tgtaagttcc
     9421 gctaatttgg ccgaacatgc aggctttgct tcatctagaa atacaatgtc cgctacagcg
     9481 gctgcttctg caaatcgctc gtttgagact tcttcgcttg cgtacggcgg atgttcagcg
     9541 tgatcatacg gattcccaat aacggaatac aagtgcgcta cgtttccttt catcgtgtaa
     9601 gacaccagtc ttgttctgtg gctctgcatc cggtagctgt gcggtgttcc cgccggaatg
     9661 ttggcataat cacctgatat taataaatag cgttcaccat caagtgtcag ttccagtttc
     9721 ccgtccaaaa cgagaattcc ttcatgtgtg tccttgtgga cgtgaagcgg aaaggcatct
     9781 ccttttcccc cggaaagaag cacgatctca aacaaatcac ctgtgctcct cccattcgcc
     9841 atcaccgtgg caacctgtct gccgaacaga tagcgctcgc cttctccgct ccggagcaaa
     9901 taaggcattt tttctttagg caatgaatgt gtacataatg ttttcatatt atcgcttcct
     9961 ccaatttaga ccagtctata tattatcatt catttgtcta gaccgttcta tataattgta
    10021 ggagaaagga taacaaaatg ctaccctttt tttctcacca gcactggtat ttgttcggca
    10081 atgagaagaa gaggcgtttt gtctttattc gttaacgaaa gcatgatgcc gccctcaatc
    10141 atcgaattaa tcagcgttcc aagctgattt gcttcttctt ctgcaaatcc gttttccatt
    10201 aattttctgg caaaaaccgc ttcccagctt ttaaacacct tcatgcaaac cgtccgcagc
    10261 ggttcactga ttaacgctgt ctcactcgcc agcaaaccga ctggaatacc tttaatgctt
    10321 tctgtgttgt caaattggct ggctgttttt ttgataaaaa gctgaatcgc ttcaacagga
    10381 tcagaggatt catccatgct ttgctgtatc agatgttcaa cgatcttacc tgtatatgta
    10441 accgcttcaa ttgctagttc ttctttgcca ttcggaaaaa agtgataaag cgatcctttt
    10501 ggagcaccgc tttcttttac aatctggttc aaacctgtcg cgtgatatcc ttgcagctgg
    10561 aacagacgtg acgccgtgtg aaggattttt tcacgtgaat ctcctctgct agtcattaaa
    10621 acattccctc ctaggtatgg tagagcgact tatataatat aaaaaagaac cctgtgattg
    10681 tcaaaagggg taagaccctt ccggatgggg taatgtacaa aaacagcgtc taggagggat
    10741 ctctcaatga caatcgatca ttcagtcaca aatacagagc agcttgaaca acagaacccc
    10801 gccataaaaa caaagctcaa actgaaaaag cttaaggatc aggtgatcgt cattaccggc
    10861 gcttcaagcg gtatcggact tgtcacggcg agaatggcag ctgaaaaagg cgcaaaggtc
    10921 gtggcagcag cgcgaaatga agaggcgctg aaggagctca ctgatgaact taaggaaaaa
    10981 gggcacgacg ccatatgggt aaaggcggat gtcggaaaag aagaggacgt caaccgcatc
    11041 gcagaaaccg cgatcagcac attcggccgc tttgatacat gggtcaacaa tgcggccgtc
    11101 tcgacttt
//
