LOCUS       c00006_JADPFP0..       16645 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JADPFP010000015.1 Lacticaseibacillus rhamnosus strain
            1001270B_150601_F12 NODE_15_length_65301_cov_36.587, whole genome
            shotgun sequence.
ACCESSION   JADPFP010000015
VERSION     JADPFP010000015
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 05:08:26
            Original ID  :: JADPFP010000015.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16645
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16645
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3863:11645]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3864..11645
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..16645
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16645
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(2..370)
                     /locus_tag="ctg6_1"
                     /transl_table=11
                     /translation="MTKYSSEFKVKVVQEYLSGRVSYNSLCTKYSIPSTKPVREWVKQA
                     QVHGLESLQRKHTKTFYSLEQKLAVVDYYQTSGAGVVSAAAHFGINASQVAVWMKIFKT
                     EGVAGLRPKPRGRRSTVKH"
     CDS             complement(466..1821)
                     /locus_tag="ctg6_2"
                     /transl_table=11
                     /translation="MKAKDNQADRGDQPLSEKHHMQIPWYDVIVSEERQADHATLEERA
                     SLVGRVGIMLLACGTGAWRVREAMNTVARALRMSCSADIGLISLSYTCFSNNHAYSEVL
                     SLPKSGVNTDKLDALERFVRHFDKEYATQTVRDIHHRLDQIQKMSGNYDPLRAGLAAAL
                     ACCAFVFLLGGGPIEMVCCFVGAGIGNWLREIMIRRNWTLLACIGVSVAVACLVYFIAF
                     RGLEMGLGIAARHEAGYIGAMLFVIPGFPFITSMLDISKQDMRSGMERLLYALMITIVA
                     SLVGWLVAMVVHLRPENFVDLGLSPILLLVYRLIASFCGVFGFSVMFNSPRRMAIQAGL
                     IGAVANTLRLELVDLNTIPPAAAAFIGALVAGLIASAINRVDGYPRISLTVPSIVIMVP
                     GLYIYRAVYNIGLNNIGVGAEWMTRAALIIMFLPLGLFTARLIMDSRWRQSD"
     CDS             complement(2001..2354)
                     /locus_tag="ctg6_3"
                     /transl_table=11
                     /translation="MDYEEELETKGYIDCLLHELHEQPQLIRQTNIEEVVERTKEEIIR
                     DGFHGYELRRHVFRMILRIDFILTTESVRLSQEGRDAIDELRRIANGQKKEDPRRFLRI
                     RHFLAQRFQHHMQ"
     CDS             complement(2472..3851)
                     /locus_tag="ctg6_4"
                     /transl_table=11
                     /translation="MMDPKKLATTEYYQHRFRNFSTMIIMPSTILFLGLLLFLIFARRE
                     VTVLTAAEIEPVKAAVTVQATAANRIVSNRMKEGKRVKKGETLLVYHDVANPTQIKLLK
                     QQLATLKEQQQQLDVLKQSVTENKDLFSKADRFGYQQQVQDYLSQRRVLTLTAEAEQAT
                     QTVASEKNKEIDRLLSASIQTSQAKMAAISEAKAAIQANKPLPSRHAYHYLYQQYESEI
                     KNTDAEAQANLKRQYLAQLQTQLDEEQTNLTSLEQQRAGQKQADVSAQKAGETQANLTA
                     LQSRLQQTAVAEQTKVQQQVQADEAKLATLNDETQNYHVKASASGVLHLETALAGNQYV
                     PSGSVLARILPDLTEQTVADIKLGVSPTEIMSIKRGQKVRLRIAENVPTPTILDGRVYA
                     IDVAPTRDPKVGNFFTVKARVKLSKSQRQSLYYGLAGQASVITGTKTYWDYFADKMFNH
                     R"
     CDS             complement(3864..6056)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 311.7; E-value:
                     1.6e-94)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_5"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1107.2,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.7e-41, bitscore:
                     132.5, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKYTPKLGQITYYKRFYTAQVDERDCGVAALNMLLKYNGSDYSL
                     AHLRELAKTNQDGTTALGIVRAAEALAFETKPVQANMQLFDLEDVPYPFIAHVLKRGEL
                     LHYYVVFKATRTSILIGDPDPSVRMTWLSREVFEKEWSGVAIFIAPAPQYQPRKEDKGS
                     LFAFVPMLAKQKGIIANIILAAVLITVISIVGSYFLQSIIDTYIPNAMRTTMGMIASGL
                     LVAYLLQAVLTYGQNFLMAVLGQRLAIDVILGYVRHLYELPMSFFSTRRTGEIVSRFAD
                     ANKIIDALANTIMTLFLDVWIVLILGIVLGIQNGTLFLVSLIAVPCYLVIVFAFQRPFD
                     RLNQETMESNAILSSSIIEDLNGIETIKSLTGERVSYERVDREFLTYLKKSFSYTKADQ
                     LQQAIKGLLKLALNVVVLWIGASLVIANRMSLGQMLTFNALLSYFTNPLESIINLQPKL
                     QMARVANNRLNEVYLVESEFKEQRHLTERHLIEGPIRVRDVSFKYGFGQDVLKNVNLEV
                     PENAKYTIVGMSGSGKSTLAKLLVGFYPVDADKGTITFNGIPVKDINLTTLRQYIEYVP
                     QDPFIFSGTVLENLTLGSRSDVSEQDLTQACLAAEIAADIANLPQQWQTKLSESGSILS
                     GGQKQRLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIA
                     AKTEQIVVMDHGKIVEQGDHATLLAQDGYYARLVHE"
     CDS             6671..7966
                     /locus_tag="ctg6_6"
                     /transl_table=11
                     /translation="MTLMSDTTYFFITLPIFLTGIYFLTFVFESRSRVIHITFWSVFGT
                     LLSLLLSTYGEVFFFIIYACYVAKTTSRSNVFWVFIFMEVNLIVITAHTTSTQALVLLK
                     ARLDPCILIADSVINLAVFIATIWLLSKKKEQIIKLRDLVREQNKLQRSILIYTGANCA
                     SLYCFEATWNLIDLNNFLSWLSLGVFLLSVVISLYSIFFILKSYKYYIELIWIKRAESS
                     QRAYYATLAQQQKRTDKLLHDYKNLLATLQLSMDQSTHNISSETRDVVSKAQQALSQVE
                     FNQETFDAIKSDSLKSLLYLKWTEALHQNIKMYVHIEGIIEPLDSSTSFAVIRALGILI
                     DNALEETSRSGNSKFSVLLINSSSYLEVNVINDVTAGFELSNLNQSGFTTKGHGRGKGL
                     TIINELIEQNKKISLKKKVKDNQLKITLFVWR"
     CDS             7971..8747
                     /locus_tag="ctg6_7"
                     /transl_table=11
                     /translation="MSKNKTILNIYILEDNPDYLTFIQETVQQYLLIEELPAKIRLATT
                     SATELLATIDWSAINDSIFLLDIELGDSATSGVDVATAIRKKSYYVDILFITSHVDEAL
                     RILEHKIAPLDMINKNSPSKTEKKIRNNILYAIKRLKARQVASPRLFSYSINSSIFSLE
                     MDELIYIQTAPGVSGTLELHAENEITTFPGNLKELATKYTNLCRCHKSILINPAHVLRL
                     DITNRFVYMDNQDKLEVSIRRIGELRNILTGTRALS"
     CDS             complement(9154..9336)
                     /locus_tag="ctg6_8"
                     /transl_table=11
                     /translation="MTVVLYSMLLILAFFFTFVFVTAISWQMIDLLRHRLHARTSFWEK
                     CSQLTQLAISILPFS"
     CDS             complement(9861..10106)
                     /locus_tag="ctg6_9"
                     /transl_table=11
                     /translation="MTILKTMHTWLNEASFWIIVCIFFGGFSLSDSLNKLIVDCLGFDF
                     FIVRAFIEMLSIFIVLILFSKMSVASSRVKDHKRSK"
     CDS             complement(10233..10322)
                     /locus_tag="ctg6_10"
                     /transl_table=11
                     /translation="MVSFTDSFGADQTPIAMLVGMGLLSMDDA"
     CDS             complement(10356..10655)
                     /locus_tag="ctg6_11"
                     /transl_table=11
                     /translation="MNKLKWFAGGNERAEQAIQLIDELLHDFDDSSFRSDRIRTVLRNN
                     KEALIHKQAAVPFILSRMNLEISNALLQNNILLTKQQSDKFEQLSSLANIRYGY"
     CDS             complement(10833..10991)
                     /locus_tag="ctg6_12"
                     /transl_table=11
                     /translation="MTKLNEAELSKISGGIGPLAIPVAAILGFLATDAWNHADELVAGV
                     KQGWERS"
     CDS             complement(11460..11645)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_13"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 9.4e-09,
                     bitscore: 27.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHLKTLNTADLASISGGDNGNLWTFIGKAIGSTARSWAEGAMFA
                     PAIGPAKEIVDKLNGN"
     CDS             complement(11705..11890)
                     /locus_tag="ctg6_14"
                     /transl_table=11
                     /translation="MTMRTGLALKEISGKMLELTSGGNVPLSNCSVDPPNERHPPAYES
                     AFKYKLPIVHPIKVAT"
     CDS             complement(12276..12461)
                     /locus_tag="ctg6_15"
                     /transl_table=11
                     /translation="MSTRLTKLVDYGLIIATIIFAIYTVTSAFGWTNHGSFVTPMLILM
                     TLLMLLSEREEKQKSA"
     CDS             complement(12511..13317)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_16"
                     /sec_met_domain="Abi (E-value: 4.1e-15, bitscore: 48.1,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERKRHLLLSPGFCVLYILLLVVLISQLLLIPAVYMLKLDFWAGN
                     ILFKAIILLVMIALNWLLLKQVIVLKVTLSRPRLKPVIIWGLVLMLIAWFTVTNRTPID
                     VLQAAVIGTIAAVPEEYLFRGVMLGELIRAFYVAHHRHAKYQLLVCIGLSSLVFSLAHL
                     SNLPAQGLVITIAQVIQAFGMGAIFAALYIRYGSLLMPILIHFLIDFVITLVSGPYPKE
                     APSDPNAITMTIVHAFLIAGIYLAIALRLFRRGQNNEKFLARLSHS"
     CDS             complement(13638..14078)
                     /locus_tag="ctg6_17"
                     /transl_table=11
                     /translation="MAFSVAFSQALEITAYVNAKSQAQHEDYLSIQKISEMLNIPVPSI
                     KKISSTLKKSGILTSKTGLNGGLRLAKTPQTITVYEILAAIEGTAPLFKLHQEIDPAAF
                     VNGERVTSWLVASTNVLNRAEDAMVQVLKQTSIADLAEAAEA"
     CDS             complement(14133..15560)
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 325.1; E-value:
                     9.2e-99)"
                     /gene_kind="transport"
                     /locus_tag="ctg6_18"
                     /transl_table=11
                     /translation="MSKEEDKELINDGLADDTVIEETDAAITQSQRMSATQVIILGLAL
                     IGAFLGVLDTSIVYTGTVKMAAQLHLNAGALSWVQVAYALTYAGLMLVGGKLGDIYGRK
                     PLFIASLAIFGVGSLAVGAATNALVMISFRAVQGVGAAILAPNCLALLTDTFQGKARQR
                     AIGYYASVIGAGAAVGLVIGGFFATFASWRVGFYMNGPIALIMVGIAARYLPSAKRQTG
                     KIDWIGTILSVLAMTSISYGLDGSPWPIPTLLISAVLWIAFIASQGRVAHPTMPLEIFT
                     DRERMASYVSSLLFSAAAIGFWFYTPQFMQGVLGLTPFMTALGMVPMAILLFIVAVKAR
                     TFVDRWRNSRVMIFGFVTVLLSLAELAVASRFANYWFLLLGTLGFAVGFALAFATLATS
                     GLARIRPEISGAASGVYNTARQFGGALGLAIFAASTASLSKIADVFGQAMLIGVGMTIV
                     GLILVVTLIIPAEKAAK"
     CDS             complement(15733..16065)
                     /locus_tag="ctg6_19"
                     /transl_table=11
                     /translation="MNMVQRNQILFILTGLNLSLKKAASGGLMETEAREVVDEALAILK
                     RPNVLKNRAADYALSRLYARFTRLIGLQGMKLSAEANQWWQAVKDFMENDIHGELSQVG
                     GPHFII"
ORIGIN
        1 tatgtttcac tgtagaccgc cttcctcgcg gtttcggacg caacccagcc actccctcag
       61 tcttgaagat cttcatccag acagccacct gcgaggcatt gatcccgaaa tgagcagccg
      121 cagataccac acccgcacca ctggtttggt aatagtctac cacggccagc ttctgttcca
      181 gagaataaaa tgtcttcgta tgctttcgct gaagagattc aagtccatgg acttgggctt
      241 gcttaaccca ctctcggact ggtttcgttg acgggatact gtatttagtg caaaggctgt
      301 tataggaaac ccgtccagaa agatactcct gtacaacctt caccttgaac tcacttgaat
      361 atttagtcat aaaaataccc cacaatcatt agagtatctg tctaacaatt atggggcact
      421 tcattttgaa gtggggttat ttgtgttgct aaaaagttat actgatcaat cgctttgccg
      481 ccagcgagaa tccataatca agcgagcggt aaacaagccc agcggtaaaa acataatgat
      541 aagtgcggca cgcgtcatcc attcggcacc gacgccaata ttattcaatc caatattgta
      601 aactgcccgg taaatataca agccaggcac catgatgacg attgatggca ctgttagcga
      661 aatccgcgga tagccatcaa cgcgattaat cgccgacgca atcagtccgg ctaccaacgc
      721 gccgataaat gccgccgcag cagggggaat cgtattgaga tccaccaatt caagccgcaa
      781 cgtattcgcc actgccccaa tcaacccggc ctggattgcc attcggcggg ggctgttaaa
      841 catcaccgag aatccaaaga ccccacaaaa gctggcaatg aggcgataaa ccaaaagaag
      901 gatcggactc aggcctaagt cgacaaagtt ttccgggcgt aaatggacaa ccattgcgac
      961 cagccaacca accagcgaag ccacaatggt aatcatcaac gcatacagta gtcgttccat
     1021 tcccgagcgc atatcctgct tcgaaatatc cagcatactg gtgataaatg ggaagcccgg
     1081 aatcacaaac aacatggcgc cgatataccc cgcttcatgc cgcgccgcaa tgcccagtcc
     1141 catttccagt ccgcgaaaag cgataaaata aaccaagcag gcaaccgcca cactgacacc
     1201 gatacaagcc agcagtgtcc agttacgccg aatcatgatt tcacgcagcc aattaccgat
     1261 ccctgcacca acaaaacaac aaaccatttc gataggaccg ccgcctaaca aaaagacgaa
     1321 agcgcaacac gccaaagcag ctgctaatcc ggcgcgcaac ggatcgtaat tgccagacat
     1381 cttttgaatc tgatcaagtc gatgatgaat atcccgcacg gtttgagtcg catactcttt
     1441 gtcaaaatga cgcacaaaac gttccaacgc atccaacttg tcagtattca caccgctttt
     1501 tggcagtgaa agcacctcag aataggcatg gttattgcta aagcaggtat acgataagga
     1561 aattaagcca atatctgctg agcacgacat ccgcaatgct cgagcaacgg tgttcatcgc
     1621 ctcacgcacg cgccacgccc cggtaccaca cgccagcaac atgatcccga ctcggccaac
     1681 gagtgacgcg cgctcttcaa gggtggcatg atcggcttgc cgctcttcgc tgacaatcac
     1741 gtcataccac ggaatctgca tatgatgttt ttctgaaagc ggctggtctc cccgatccgc
     1801 ttggttatct tttgccttca taactcgtgc taatccttct tcttataggg attgtctttt
     1861 tcaaaaaaat tgaaaataaa cattcactat tctagcacaa ttcataacag ggtgtatttt
     1921 tgactttttg aaactaatga atttgaacgc cttattcatg acaagcacgc acaaactagc
     1981 aatcatttct cggtctcaac ttattgcata tgatgttgga atcgctgcgc cagaaaatgc
     2041 cggattcgca aaaagcgacg aggatcttcc ttcttctgtc cattagcaat ccttcgtagt
     2101 tcgtcaattg catctcgtcc ttcttgactc aaccgtacac tttcagtcgt gaggataaaa
     2161 tcaattctta gtatcatccg aaaaacatgc cgtcgtaatt catagccatg aaaaccatcg
     2221 cggataatct cttccttggt tctttccaca acttcttcaa tattcgtttg gcggatgagc
     2281 tgcggttgtt catgtaattc atgcaacagg cagtcgatat agccttttgt ttctaattct
     2341 tcctcgtaat ccatacgccg atcaccgcct ttcatttgac taacttgatc cgcatcgttt
     2401 tttatggtca ttttcttaaa taatgggcat cgccttttcg ctactaaaca acaaaagcgg
     2461 taaataccga tttatcgatg gttaaacatc ttatctgcaa agtaatccca ataagtcttt
     2521 gtgccggtga taacagatgc ttggccggct aatccataat aaagggactg ccgctgcgat
     2581 ttagataatt tcacccgcgc cttgaccgta aagaagttac caactttcgg atcgcgtgtt
     2641 ggggcgacgt caatcgcata aacccggcca tctaatatgg taggggtcgg cacattctca
     2701 gcaattcgca ggcgtacttt ctgcccacgc ttgatgctca tgatctctgt cggcgaaacg
     2761 cctaatttta tgtcagcaac cgtttgttcc gttaaatccg gcagaattcg tgccaacacg
     2821 cttcctgaag ggacgtattg attcccggcc aaggcagttt ctaaatgcaa aacgccactg
     2881 gcacttgctt tgacatgata gttttgagtt tcatcattca aggtagctaa cttagcctcg
     2941 tctgcttgga cctgttgctg aaccttcgtc tgttccgcaa cggctgtttg ctgcaaccga
     3001 ctttgtaatg cggttagatt agcctgagtc tctcccgctt tttgagccga tacatctgct
     3061 tgtttttgac cggcccgttg ctgctctaaa gacgtcaaat tggtttgttc ctcatccaac
     3121 tgtgtctgta attgagcaag gtactggcgt ttaaggttcg cctgtgcctc cgcgtcggta
     3181 ttttttatct cactttcata ttgttgataa aggtagtgat aggcgtggcg actgggcaag
     3241 ggtttgttcg cctgaatcgc cgcttttgcc tcggagatag cggccatttt tgcttggctc
     3301 gtttggatac tggcgcttag taaccgatca atctctttgt ttttttcact agcgacggtt
     3361 tgggttgcct gctcagcctc tgctgtcagt gtcagcactc gccgttgact cagataatct
     3421 tgcacctgtt gttgatagcc gaatcggtct gcctttgaaa aaagatcttt gttttcggta
     3481 acactttgtt tcaaaacatc caattgctgc tgttgctctt ttagcgttgc cagttgctgc
     3541 ttgagtaatt taatttgtgt tggattagcg acatcgtggt aaacaagtaa ggtctcgcct
     3601 ttcttcacgc gcttgccttc tttcatgcgg ttcgagacga tccgattggc ggccgtcgcc
     3661 tgaactgtca cggctgcctt taccggttca atttcggcag ctgtcagcac agttacctcg
     3721 cgccgagcaa agatcagaaa caatagcaag cctaagaaaa gaatcgtact aggcataata
     3781 atcatcgttg aaaaattgcg aaagcggtgc tggtaatatt cggtcgttgc aagttttttg
     3841 ggatccatca tctaaagctc acctcactca tgaaccaggc gcgcgtaata accgtcttgg
     3901 gctaacaacg ttgcatggtc accttgttcc acaattttgc catgatccat caccacaatt
     3961 tgttcggttt tagccgcaat agttaagcga tgggcaacaa aaataatggt ccgatccgtc
     4021 attgccagca agcgatcgac aatttttcgc tctgtaatgg tatccagact gctggtcgat
     4081 tcgtcaaaaa tcagtacttt tgccggtgac aacaaggccc gtgcaatcgc cagccgctgc
     4141 ttctgaccgc ctgataaaat actgccgctt tctgacaatt tggtctgcca ctgctgcggt
     4201 aagtttgcga tgtctgcggc aatttccgca gccaaacacg cctgcgtcaa atcttgttcc
     4261 gaaacatccg aacggctacc taacgtcaaa ttctccaaca ccgtgcccga aaaaataaac
     4321 ggatcctgag gtacatattc aatatattgc cgtaatgttg tcaggttaat gtctttgacc
     4381 ggaatgccat taaacgtgat ggttccttta tcggcatcaa ccgggtaaaa gccaactaat
     4441 aattttgcta atgtcgactt accagaaccg ctcatgccaa caatggtata tttagcattt
     4501 tccggcactt caaggttgac gtttttcaat acatcttggc caaaaccata tttaaacgag
     4561 acatcccgaa cgcgtatcgg accttcgatt aaatgccgct ccgtcaagtg ccgctgttct
     4621 ttgaattccg attcgaccag ataaacttca ttcaggcgat tgttagcaac ccgcgccatt
     4681 tgtaactttg gctgtaggtt gatgatgctt tcaagcggat tcgtaaagta tgacagcagt
     4741 gcattaaagg tcagcatctg ccccaagctc atccgattgg caatcaccaa acttgcccca
     4801 atccacaaca ccacaacgtt caacgccagc ttcaacagac ctttaatcgc ttgctgtaat
     4861 tgatctgcct tggtgtaact aaacgatttc ttcagatagg ttagaaattc ccgatcaacc
     4921 cgttcatagc taactcgttc gccggtcagg gacttgatgg tttcaatgcc attcaaatct
     4981 tcaataatcg atgaactcaa gattgcgtta ctttccatcg tctcttggtt caaccgatca
     5041 aacggccgct gaaatgcaaa aacaatcacc aaataacacg gcacggcaat caatgacact
     5101 aaaaacaaag tcccattttg gatccctaga acaatgccta atattaggac aatccagaca
     5161 tccaaaaaca acgtcataat cgtattcgcc agcgcgtcaa taattttatt ggcatccgca
     5221 aaccgcgaca caatctctcc ggtccgccga gttgaaaaaa acgacatcgg caattcatat
     5281 aagtggcgca cataccctaa aatgacatca atcgcaagcc gctgccccaa caccgccatc
     5341 aaaaaattct ggccataagt caacacagct tgcagcaagt aagccaccaa aaggccacta
     5401 gcaatcatcc ccatcgtcgt ccgcatggca ttcggtatat acgtatcaat aatagactgc
     5461 aaaaaatacg acccaacgat actaatgacc gtaatcaata ccgcggccag aataatgttc
     5521 gcgataatac ctttttgctt agccagcatg ggtacaaacg caaacaaact gcctttgtcc
     5581 tccttacgcg gctgatactg cggcgccggt gcaataaaga tggccacacc cgaccattct
     5641 ttttcaaaca cctctcgcga aagccaggtc atgcgcactg acgggtcagg atcgccaatc
     5701 agaatactcg tgcgcgttgc tttaaaaaca acatagtaat gaagcaattc accgcgcttc
     5761 agcacatggg caataaacgg ataaggcaca tcctcaagat caaacaactg catattcgcc
     5821 tgcaccggtt tcgtctcaaa cgctagtgct tcagcggccc gaacgattcc caaagccgtc
     5881 gtgccatcct gatttgtctt cgctaactcg cgcaagtggg ctaacgaata gtccgaccca
     5941 ttgtatttaa gcagcatgtt taacgcagcc acaccacagt cacgctcgtc aacttgtgcg
     6001 gtgtagaaac gtttgtagta ggtgatctgg cctagttttg gggtgtattt aaccattaac
     6061 tctcctcgct tattaagcca ttagattcag gcctctttta tgagccgata taccatgacg
     6121 tttagtcaaa aatacaggta gtgaatcccc aaatttgggg ttaccctttt gatataagca
     6181 ctgtaagatt tagtttttta catttaaaat gtgtggtagt atattttaga gcaggattaa
     6241 tagcgtataa aaataaatat taaaattaaa agcactttta tatatctaaa tatttatttt
     6301 tatacgttga aggcaatcgt ctgtctggcc tttaatgctt cccctgaaac tgttctatga
     6361 gccactttct caaattatta aatgttgagc ttattggtcg gccaccacca agtatctccg
     6421 taagacgatc atccgaaatt acgctgcttt tcatctgacg ctgaaactcc tttttgttgt
     6481 tcatttcaac ctacctccta cgatttattc ttctgtattt aacctaacat gtcgtgagct
     6541 ttttagggcc tacaaaaaat aaacgtcgtg ttttggccat ttaacgttat atcgttagca
     6601 tatgacgtca tttattttca ttcggtatga agaacttgcc atactttcat aactagcgga
     6661 ggttttctat atgacactga tgtcagacac aacctacttc tttataaccc ttcctatttt
     6721 tttgactgga atttactttc ttaccttcgt tttcgaaagc cgttccagag ttatccacat
     6781 tactttttgg tcagtcttcg gaacgcttct gtctttgctc ctttcgactt atggcgaagt
     6841 cttctttttt atcatctatg cgtgttatgt agctaagacc acttcacgtt caaatgtttt
     6901 ctgggttttt atctttatgg aagtcaatct gatcgtcatc acagctcaca ctactagtac
     6961 acaggctttg gtcttgctca aagcacgcct tgatccttgc attttaatcg ccgactcagt
     7021 tattaactta gcagtattca tcgcgactat ctggttacta tctaagaaga aagaacaaat
     7081 tataaagttg cgcgacttag ttcgagaaca gaataaattg caacgttcca ttcttattta
     7141 cacaggcgca aactgtgcgt cactctattg ttttgaagct acttggaatc tgattgacct
     7201 caataatttc ttgtcctggt taagccttgg cgtattccta ctttcagttg tgatcagcct
     7261 ttattcaatt ttctttatct taaaatccta taaatattat atagagctca tctggattaa
     7321 acgggcagaa agttcccagc gtgcttacta tgcaacgtta gcacagcaac aaaagagaac
     7381 ggacaagctc cttcatgatt acaaaaactt attagccacg ttgcagttgt caatggatca
     7441 atcaactcac aacatttctt ctgagacgcg agacgttgtt tcaaaggcac aacaagcgct
     7501 atctcaagtc gagttcaatc aagaaacctt cgatgcaatt aaaagcgatt cgttgaaaag
     7561 tctactctat ttaaaatgga cagaagcgct acatcagaat atcaagatgt acgttcacat
     7621 cgaagggatc attgaaccgc tcgatagcag cacttcattc gcggtcattc gtgcactcgg
     7681 tattttaatt gacaacgctt tagaagaaac aagccgctcc ggaaactcaa agtttagtgt
     7741 cttattaatc aattcaagct cgtacctgga agttaatgtc atcaatgacg tgaccgcggg
     7801 atttgaacta tcaaatctta accagtctgg atttaccacc aaaggccatg gtcgcggaaa
     7861 ggggttgacc attattaacg agctgattga acaaaacaaa aaaatcagcc ttaagaaaaa
     7921 ggtcaaagat aaccagttga aaatcacact ttttgtatgg aggtaacttt atgtctaaaa
     7981 acaaaacgat cctaaacatt tatattctcg aagacaaccc tgactatcta acctttatcc
     8041 aagaaactgt gcagcagtac cttctgattg aagaactacc cgccaagatc cggctggcaa
     8101 caacgtcagc aaccgaactg ctcgcaacta ttgattggtc agccatcaac gatagtatct
     8161 tcctccttga tatcgagctg ggagattcag cgacaagcgg cgtagatgta gccacagcca
     8221 ttcggaaaaa gtcatattat gtcgatatcc tcttcatcac tagccatgta gatgaagctt
     8281 taaggatttt agagcacaaa atcgcacctc tggacatgat caacaagaac tcaccttcaa
     8341 agacagaaaa gaaaattcga aataacattc tttatgcaat aaaacgtcta aaggcgcgtc
     8401 aggtcgcatc tcccagatta tttagctaca gcatcaactc cagtattttt tcacttgaaa
     8461 tggatgagct catctatatt caaactgctc ccggcgtctc agggacactg gagcttcatg
     8521 cagaaaatga aatcacaacc tttcccggca accttaagga actagcgacc aaatatacca
     8581 acttatgtcg atgccataag agtatcctga ttaatcccgc acatgttttg cgtctggaca
     8641 tcacaaaccg attcgtttat atggacaatc aagataaact tgaggtcagt attcggagaa
     8701 taggcgagtt gcgcaacatc ttaacaggca cacgggcttt atcttaagaa gagtgtgact
     8761 gggcaatcat cctagatttc tgttaatcaa cacagctgaa cgcacaaata acgcatcctc
     8821 aatatcaagg gtgcgttatt tggttggttt atacaggttg gaaatactat tcctcctgaa
     8881 aggttttatg ccaatctgtc atcggttcta cttcaaccaa agcgctatcg actgacccat
     8941 tcgataacca gcgtcatata tcccttttaa aattcccggt gaaaagtacc aaaacgccat
     9001 tattaaaacc ccaatggcga caagcaacga cactttctgt tggaatgata atcttgcaaa
     9061 ttgatcgatt acgctcacct cgtttacaaa cagacttatt tttacttctt tcagcaatcc
     9121 attagtaaca tgttctttat gttctcccac cttctaagaa aaaggcaata tactaatggc
     9181 caactgcgtc aattgggaac atttctccca aaaagatgtt cgcgcatgaa gccgatgtct
     9241 taagaggtct atcatctgcc agctgatcgc agttacaaat acgaatgtga agaaaaatgc
     9301 cagaatcaaa agcatagaat ataacacaac tgtcataagc aaagctcctt gagtcttcct
     9361 ttaaacttac attgaggcgg caaattagcg agcacaggtt cggagatacc atacgttctg
     9421 ctaaggtcgg tcatacaagc aagaaatcac aaaaatgaca ccattttagc tatttaatgc
     9481 tatttccgaa aggccttttg ctgtcaggaa gaaaaaacaa tcgtgggttt tgaaagctca
     9541 tcttatttag tatctgttct gccatactca cgcgcaagat ctcctgattt gtatttttgt
     9601 ttcaatacaa atcaggagac ttttgcggtt tttggctgat agaacacagg gtaacaagat
     9661 tctgacacta aaagcagttc ccaaatatca gtagtgtccc ctaaaatctc atttgccgtc
     9721 atgaacagcc gatattgcat tattatggcc tggcagatag ctgtgtcaca atagttgctg
     9781 tctctcggtg ctgacaggct tcccactgac aatgacgctg ccgccttacc aatacttcga
     9841 aatcaaacaa agaaaatttg ttatttagag cgtttatgat ctttaaccct tgaagatgcg
     9901 acactcattt tagaaaaaag aatcaaaaca atgaagattg aaagcatctc aatgaacgcc
     9961 cggacgatga aaaaatcaaa acccaagcaa tcgacaatca gcttgtttaa gctatcactg
    10021 agcgaaaacc cgccgaaaaa gatacatacg ataatccaga aagaagcttc attaagccat
    10081 gtgtgcatag ttttaagaat cgtcatcgta cctccgcttt gctcatcact aaatcattta
    10141 tcgaccgatc agttttggct ctgtcttttt aagttagacc gttatattcg aaactagttt
    10201 gcctaagtcg ccgttataaa ttggacaacc ttttaggcat catccattga caacaagccc
    10261 ataccaacca gcatcgcaat cggagtttga tctgcaccaa atgaatcagt gaagctaacc
    10321 ataatcaagc gcgctcaccg ttttagtagt ggcttctagt acccatatct gatattcgcc
    10381 agcgaagaaa gctgctcgaa tttatcagat tgttgcttgg ttaacaaaat attgttttgc
    10441 aacagggcat tagagatttc tagattcata cggcttaaaa taaatggaac cgctgcttgc
    10501 ttatgaatta aggcttcttt attgttcctt aacactgtcc gtatgcgatc actacggaaa
    10561 gaactgtcat cgaaatcgtg aagcagctca tcgataagct gtatcgcttg ttcagcccgt
    10621 tcattcccgc cagcaaacca tttcaatttg ttcatcattc actccaaaaa acgttgtgct
    10681 tgtgcatctt cacttgtaac acgtttggca ccgtgcattg ccagatctgc cgtagcaata
    10741 acggtaagtg catgctcgcc cacagataaa aacttgttct gggaagagat acttttacaa
    10801 cggcgaaatc gctaaaaatc aacgcaccgt tattacgatc gttcccatcc ttgcttgacc
    10861 ccagctacca gctcatcagc atggttccac gcatctgttg ccaggaatcc aagaatagca
    10921 gcgacaggga ttgcgagcgg tccgataccg ccggaaatct tactcaattc agcttcattc
    10981 aacttagtca ttaaaattac ctccttgtat ttgtaagaaa ctactcgcca gttgatccaa
    11041 aagtctttgt tatggatatt gtggcgataa aatgctcatc taccgcacaa ctttttgcaa
    11101 atacaaccat ggagtcatca gcggcatgcc tggattaaag ccacttgacc ttcaccatcg
    11161 aaattctgcc acttggtttg tatggcagca ttacagcgta cggcctaggc attgaacgga
    11221 acactcaaag tttaagcgta ggtaataaac cagatggcat tcaaaatata agcacgttta
    11281 aaggctatct gatgctcact gtcgagatat ttatcattcc aaacgcgata gtgaccatct
    11341 tttttacagc acgtatatac caaaacacct aatagatata ccaagataaa cgtagctaac
    11401 attaaaagat ttatcttatt catacgttcg cccgttcgag tgcctattca tcccggatac
    11461 taattgccgt taagtttatc aacaatctct ttggcaggac caatggctgg tgcaaacatg
    11521 gcgccttcag cccaagaacg cgcggttgaa ccaatggcct tcccgataaa ggtccacaga
    11581 ttaccattat cgccaccaga aatacttgcc aaatcagccg tgtttaaagt ttttaaatga
    11641 tccatgttct tcctcctttt tcctttatga gcctttcaat ctatctatca gcctaaatta
    11701 tcacttaagt cgccacctta attggatgaa caatcggcag tttatactta aatgccgatt
    11761 cgtaagctgg cggatggcgt tcgtttggtg gatccacact gcaattggat aaaggaacat
    11821 tcccaccgct cgtcaattca agcatttttc ccgagatttc cttcaaagct agtcctgttc
    11881 gcatggtcat cccattttcc tcctttccct ttgttagaag gacttccctt cttccccatc
    11941 aatataaagt agacagccag gtttgtggga atgaattttt taacgtcgat ttttgcaaga
    12001 aaatcgtcgt aaaaaaccta attttgacgt ttatcgttaa aaacccggcg attatttgat
    12061 attgccgcct tctcttcaaa actcaagcaa ctgcaactgt atttactttt acccatgtct
    12121 ttttcgccac tgtgagcatc cagtcttaag ccaacttaga aaggcgatta ggctcgcggc
    12181 cagcatgtgc atccattcgc cggggaaatg atgacaaact gcacacatat aaccgacaat
    12241 aaatgttaat aagcagcgcc aaaatctttt ttgattcacg cgctcttctg cttttcctcc
    12301 cgctcgctta acagcattaa caacgtcatc aaaatcaaca ttggcgtcac aaaactgccg
    12361 tgattggtcc atccaaatgc cgatgtgacc gtataaatgg cgaaaataat ggtagcgatt
    12421 atcaacccat aatcgactag tttagtcagt cgcgtagaca tcgtttttct ccttaaactc
    12481 gttctatcat aattgataca tacagccagt ttacgaatgc gacaatcgtg ccagaaactt
    12541 ttcattgttt tggccacggc gaaaaagtcg cagtgcaatc gctaggtaaa tcccggcaat
    12601 aaggaatgcg tgaacaatcg tcatcgttat agcgttggga tcactaggcg cttctttcgg
    12661 atacggtcca ctaaccaaag tgataacaaa atcaatcaaa aagtggatca atattggcat
    12721 aagcaacgat ccgtaacgaa tataaagtgc tgcaaaaata gcccccatgc caaatgcctg
    12781 gatcacttgg gcaattgtta tcacaagccc ttgagcaggc aaattactca ggtgagccaa
    12841 tgaaaaaaca agactgctta accctatgca aactaagagt tggtatttgg cgtggcgatg
    12901 atgggcaaca taaaacgccc gaatcaactc gccaagcatg acgccacgaa acaaatactc
    12961 ttcgggaaca gcggcaatag taccaatcac agctgcttgc aagacgtcaa tcggtgttcg
    13021 atttgtaacc gtgaaccaag cgataagcat caagaccagt ccccaaatga taactggctt
    13081 caatcgtggt cgactaagtg tcacttttaa gacgataact tgtttcagta acagccaatt
    13141 aagtgcgatc atcaccagta aaatgatggc tttaaataag atattcccag cccagaagtc
    13201 caatttaagc atgtaaactg ctggaattaa aagcagctgg ctgattagca caaccaaaag
    13261 caagatatat aaaacgcaaa atcctggcga caatagcaaa tgacgttttc tttccattta
    13321 tccaccttca ctcacacgtt tcaatgcaac gcagcttcga tatcgctacc cacaatatac
    13381 cgaggctgcg catgttacgg atcattaact tttaaacgtc gggttttcgc cgataatcgt
    13441 tgtgttttga aacttgacaa cacgttaatc gtctccattt ccaaaaaggt aggccaatga
    13501 agacgcactt acttcccatt tactgactgc cccacagttg cacgatcctg aaaatgccgt
    13561 aagcaaaatc gcctcatcca ataccaacgc gccaacgtta gtcttgaatg aggcgatgaa
    13621 aagttagagt tcgatattta cgcttctgcg gcttcagcca aatcagcaat gctcgtctgc
    13681 tttagcactt gcaccatagc atcttcggct cggtttagaa cgttggtgct tgctactaac
    13741 caacttgtga cgcgctcgcc gttgacaaac gcagctggat cgatttcctg atgcagctta
    13801 aataacggtg ccgtcccttc aatagccgct aagatttcgt aaactgtaat cgtttgtggc
    13861 gttttggcta atcgcaaacc gccattgaga ccggttttcg acgttaaaat accacttttt
    13921 ttaagtgtag acgaaatttt tttaatgcta ggaaccggaa tgtttagcat ttcggaaatc
    13981 ttttgaattg ataaatagtc ttcgtgttgt gcttgggact ttgcgttgac ataagccgta
    14041 atttcaagtg cttgcgagaa tgcgactgaa aaagccatcg aatatacctc ccattaggcg
    14101 attgtgtata ttctattata ccaatgatat cgttacttgg cggctttttc tgccggaata
    14161 atgagcgtga cgacaagtat taagccaaca atggtcatgc caacgccaat caacattgcc
    14221 tgtccgaata catcggcaat tttagataag ctggcggtcg aggccgcaaa aattgccagt
    14281 cctagagcgc cgccaaattg tcgggcagtg ttgtagacgc ctgatgcagc ccccgaaatt
    14341 tccggccgaa ttctagccaa acccgaagta gcgagtgtgg caaatgccag cgcgaatcct
    14401 accgcaaatc cgagtgttcc gagtaacaaa aaccagtaat tggcaaaccg tgatgccact
    14461 gccagttcag ccaatgaaag tagcaccgtg acaaatccga agatcatgac ccttgagtta
    14521 cgccaccgat caacgaaggt ccgggccttg actgccacaa tgaagagtaa gatggccatt
    14581 ggcaccatgc ctaacgcagt cataaatggc gttaatccta agacaccttg cataaactga
    14641 ggtgtgtaga accaaaagcc gattgcagcg gcactaaaca acaaagaact gacataagaa
    14701 gccatccgtt ccctatccgt aaagatttcc agtggcattg tcgggtgggc aacgcgacct
    14761 tgactagcaa tgaacgcaat ccaaagaact gctgaaatca gtaatgtggg gattggccat
    14821 ggactgccat ccaacccata tgagattgaa gtcatcgcta atactgacaa gatcgtacca
    14881 atccagtcaa tctttccggt ttggcgtttt gcactaggta aatatctagc cgcaatacca
    14941 accatgatta atgcgatcgg accattcatg tagaaaccga cccgccatga cgcaaacgtt
    15001 gcaaagaagc cgccaatgac taaaccaacc gctgcaccgg ctccaatcac agaggcgtag
    15061 tagccaattg cccgctgccg tgcttttcct tgaaaggtgt cagttaacaa tgctaaacag
    15121 ttcggtgcaa gaatggccgc gcccacgcct tgaacagcgc gaaagctaat catgacaagc
    15181 gcattggtag ctgccccgac tgccagactg ccaactccga aaatagctaa actcgcaatg
    15241 aataatggtt tgcgtccgta aatatcgcct aatttaccgc ctactagcat cagcccagca
    15301 taagttagcg cataggccac ctgcacccaa gacaacgcgc cagcattcaa atgcaattgt
    15361 gccgccattt taacggtacc cgtgtaaaca atcgatgtgt caagcacacc tagaaaagcc
    15421 ccaatcagtg ccagccctaa aataatgact tgagtcgctg acatgcgctg cgattgggtg
    15481 attgccgcat ctgtttcctc aatgacggtg tcgtcagcca ggccgtcatt gattaattcc
    15541 ttgtcttctt ctttgctcat atgagatgcc cctttctatg gttcacttag tatattccgt
    15601 ttatactatt atggcaaatc ttttttgagc aaaaaaacca cgtgttcctt aattctatgg
    15661 aaacacgcgg ctacaagcga attctattcg ggccggttac tggaatcaga ccatggcttg
    15721 ggcaacaact gtctaaataa taaagtgcgg cccgcctacc tgactcaact cgccatgaat
    15781 gtcattttcc ataaagtctt ttaccgcctg ccaccactga ttggcctccg ctgaaagttt
    15841 cattccttgc aagccgatta atcgcgtaaa ccgtgcgtat agtcgcgaca aggcgtaatc
    15901 tgcggctcga ttcttgagca cattaggccg ctttaaaata gctaaggcct catccacaac
    15961 ttcccgtgct tctgtctcca tcaggccacc actagccgct tttttcagac tcaggtttaa
    16021 tccggtcaaa ataaacagaa tctgatttct ttgcaccata ttcatgagcg ctcctccatg
    16081 tctggtagat aagtgtttgc attgagatag cgttttcttg aattgctaac tgcaatatac
    16141 caaatttatc aagcttcagg tcaaactttc gataaacgta gccttttcgc cgattaacgt
    16201 tattgcggac atgaatcgcc cggtccaaag cgcatagaaa aagccgtggt gcattaacca
    16261 cgactaatcg gaagcgcgta tttcagcata gtcgtaaaaa ggctgaaatg acacagttca
    16321 tcagcatcga acaagctcat attccatccg gctacttaat gtccgccacc ccagacaatt
    16381 ggaaaagcga ctagcccagc agccagcgcc tgatcgcgat aacgcttggc attgacctga
    16441 tctgccggca catccgcctt gatcgcattg aaaatggcga tcatctcggc tggaatcgcg
    16501 tgatgaatga gataatactt ggaaatatca tgcgatagct gggtcacgac tgcgacatag
    16561 gctgttttgt cctctgcatc ttccagttgt ttcgcgttgg attcgattat ttgctttaat
    16621 ttggcatcag ctttcacggc cggac
//
