# emapper version: emapper-2.0.1b-2-g816e190 emapper DB: 2.0 # command: ./emapper.py -i Bifidobacterium_breve/1.contigAnn/FFN/A00000108.ffn --translate --temp_dir Bifidobacterium_breve/4.eggNOG_mapper --output_dir Bifidobacterium_breve/4.eggNOG_mapper --output A00000108 --cpu 36 --keep_mapping_files -m diamond # time: Fri Jun 3 12:25:53 2022 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction taxonomic scope eggNOG OGs best eggNOG OG COG Functional cat. eggNOG free text desc. NIBLCNGB_00001 216816.GS08_02215 5.3e-107 393.7 Actinobacteria xerC_1 ko:K04763 ko00000,ko03036 Bacteria 2HB7R@201174,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family NIBLCNGB_00002 1437610.BREU_1897 3.3e-168 597.8 Bifidobacteriales Bacteria 2GKW1@201174,4D05P@85004,COG2801@1,COG2801@2,COG3415@1,COG3415@2 NA|NA|NA L PFAM Integrase catalytic NIBLCNGB_00003 326426.Bbr_0628 0.0 1160.6 Bifidobacteriales Bacteria 2GIZF@201174,4D0M7@85004,COG5001@1,COG5001@2 NA|NA|NA T Diguanylate cyclase, GGDEF domain NIBLCNGB_00004 326426.Bbr_0629 7.1e-136 490.0 Bifidobacteriales ybbM ko:K02069 M00211 ko00000,ko00002,ko02000 9.B.25.1 Bacteria 2GMHX@201174,4CYRQ@85004,COG0390@1,COG0390@2 NA|NA|NA V Uncharacterised protein family (UPF0014) NIBLCNGB_00005 326426.Bbr_0630 4.2e-127 460.7 Bifidobacteriales ybbL ko:K01990,ko:K02003,ko:K02068,ko:K05685 ko02010,map02010 M00211,M00254,M00258,M00709 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 Bacteria 2I8QP@201174,4CZZG@85004,COG1136@1,COG1136@2 NA|NA|NA V ATPases associated with a variety of cellular activities NIBLCNGB_00006 326426.Bbr_0631 3.9e-104 384.0 Bifidobacteriales efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 2GJMS@201174,4CYY6@85004,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase NIBLCNGB_00007 326426.Bbr_0632 1.1e-92 345.9 Bifidobacteriales nusB GO:0008150,GO:0040007 ko:K03625 ko00000,ko03009,ko03021 Bacteria 2IM3D@201174,4D0WG@85004,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons NIBLCNGB_00008 326426.Bbr_0633 2e-241 841.3 Bifidobacteriales carA GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1950,iNJ661.Rv1383,iUTI89_1310.UTI89_C0036,iYO844.BSU15510,ic_1306.c0040 Bacteria 2GKFA@201174,4CYQ1@85004,COG0505@1,COG0505@2 NA|NA|NA F Belongs to the CarA family NIBLCNGB_00009 326426.Bbr_0634 0.0 2221.4 Bifidobacteriales carB GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041 Bacteria 2GK5N@201174,4CZJ4@85004,COG0458@1,COG0458@2 NA|NA|NA EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain NIBLCNGB_00010 326426.Bbr_0635 6.7e-170 603.2 Bifidobacteriales pyrF GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS17585 Bacteria 2GKWK@201174,4D2UX@85004,COG0284@1,COG0284@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP NIBLCNGB_00011 326426.Bbr_0636 1.4e-104 385.6 Bifidobacteriales gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 ko:K00942,ko:K01591 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00050,M00051 R00332,R00965,R02090 RC00002,RC00409 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_2813,iIT341.HP0321,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Bacteria 2I2FT@201174,4CYUT@85004,COG0194@1,COG0194@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP NIBLCNGB_00012 326426.Bbr_0637 8.3e-136 489.6 Bifidobacteriales dnaQ 2.7.7.7 ko:K02342,ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2I2FU@201174,4D10C@85004,COG2176@1,COG2176@2 NA|NA|NA L Exonuclease, DNA polymerase III, epsilon subunit family NIBLCNGB_00014 326426.Bbr_0639 0.0 1464.9 Bifidobacteriales tetP ko:K02355 ko00000,ko03012,ko03029 Bacteria 2GJ64@201174,4CZM5@85004,COG0480@1,COG0480@2 NA|NA|NA J Elongation factor G, domain IV NIBLCNGB_00015 326426.Bbr_0640 1.9e-126 458.4 Bifidobacteriales ypfH GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689 ko:K06999 ko00000 Bacteria 2I5NR@201174,4CZJQ@85004,COG0400@1,COG0400@2 NA|NA|NA S Phospholipase/Carboxylesterase NIBLCNGB_00016 326426.Bbr_0641 4e-234 817.0 Bifidobacteriales metC 2.5.1.48,4.4.1.8 ko:K01739,ko:K01760 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ5S@201174,4CZKK@85004,COG0626@1,COG0626@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme NIBLCNGB_00017 326426.Bbr_0642 2.5e-42 177.6 Bifidobacteriales XAC3035 ko:K06191 ko00000 Bacteria 2HZQB@201174,4D18H@85004,COG0695@1,COG0695@2 NA|NA|NA O Glutaredoxin NIBLCNGB_00018 1437608.BBIA_1356 2.7e-08 63.9 Bifidobacteriales 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 Bacteria 2I8JG@201174,4CZ6W@85004,COG2873@1,COG2873@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme NIBLCNGB_00019 326426.Bbr_0643 7.2e-116 423.7 Bifidobacteriales XK27_08050 Bacteria 2GJ1U@201174,4CYTU@85004,COG0330@1,COG0330@2 NA|NA|NA O prohibitin homologues NIBLCNGB_00020 1437609.BCAL_1482 1.5e-25 121.7 Bifidobacteriales ko:K07133 ko00000 Bacteria 2GM3Y@201174,4D05H@85004,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) NIBLCNGB_00021 1437609.BCAL_1482 3.2e-15 87.0 Bifidobacteriales ko:K07133 ko00000 Bacteria 2GM3Y@201174,4D05H@85004,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) NIBLCNGB_00022 326426.Bbr_0645 4.9e-159 567.0 Bifidobacteriales ko:K07001 ko00000 Bacteria 2I8R7@201174,4CZUH@85004,COG4667@1,COG4667@2 NA|NA|NA S Patatin-like phospholipase NIBLCNGB_00023 326426.Bbr_0646 1.5e-149 535.4 Bifidobacteriales murI GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 R00260 RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 2GN4I@201174,4CZ54@85004,COG0796@1,COG0796@2 NA|NA|NA M Provides the (R)-glutamate required for cell wall biosynthesis NIBLCNGB_00024 326426.Bbr_0647 1.2e-168 599.0 Bifidobacteriales dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 iIT341.HP0566,iLJ478.TM1522 Bacteria 2GKUD@201174,4CYQP@85004,COG0253@1,COG0253@2 NA|NA|NA E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine NIBLCNGB_00025 326426.Bbr_0648 1.6e-126 458.8 Bifidobacteriales Bacteria 2GMVK@201174,4CZN1@85004,COG4243@1,COG4243@2 NA|NA|NA S Vitamin K epoxide reductase NIBLCNGB_00026 326426.Bbr_0649 6.1e-168 596.7 Bifidobacteriales PPA1328 3.1.3.97 ko:K07053 R00188,R11188 RC00078 ko00000,ko01000 Bacteria 2GNAP@201174,4CYQ5@85004,COG0613@1,COG0613@2 NA|NA|NA S DNA polymerase alpha chain like domain NIBLCNGB_00027 326426.Bbr_0650 1.8e-31 141.4 Bifidobacteriales Bacteria 2AS45@1,2HZSD@201174,31HGW@2,4D1H9@85004 NA|NA|NA S Protein of unknown function (DUF3107) NIBLCNGB_00028 326426.Bbr_0651 1.1e-297 1028.5 Bifidobacteriales mphA Bacteria 2I8R6@201174,4CYPR@85004,COG3173@1,COG3173@2 NA|NA|NA S Aminoglycoside phosphotransferase NIBLCNGB_00029 326426.Bbr_0652 7.8e-288 995.7 Bifidobacteriales uvrD2 GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKRW@201174,4CZ3A@85004,COG0210@1,COG0210@2 NA|NA|NA L DNA helicase NIBLCNGB_00030 326426.Bbr_0653 1.4e-293 1015.0 Bifidobacteriales Bacteria 2GJ9K@201174,4CYU7@85004,COG5282@1,COG5282@2 NA|NA|NA S Zincin-like metallopeptidase NIBLCNGB_00031 326426.Bbr_0654 2.5e-156 558.1 Bifidobacteriales lon ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Bacteria 2GMFX@201174,4CYUP@85004,COG3480@1,COG3480@2 NA|NA|NA T Belongs to the peptidase S16 family NIBLCNGB_00032 326426.Bbr_0655 1.6e-73 282.0 Bifidobacteriales Bacteria 2B57P@1,2IFRB@201174,31Y1M@2,4D307@85004 NA|NA|NA S Protein of unknown function (DUF3052) NIBLCNGB_00034 326426.Bbr_0656 8.6e-205 719.9 Bifidobacteriales 2.7.11.1 ko:K08884,ko:K12132 ko00000,ko01000,ko01001 Bacteria 2I2GE@201174,4CZDF@85004,COG3170@1,COG3170@2 NA|NA|NA NU Tfp pilus assembly protein FimV NIBLCNGB_00035 326426.Bbr_0657 1.7e-221 775.0 Bifidobacteriales dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iHN637.CLJU_RS06420,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188 Bacteria 2GIRV@201174,4CZVC@85004,COG0743@1,COG0743@2 NA|NA|NA I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) NIBLCNGB_00036 326426.Bbr_0658 2e-230 804.7 Bifidobacteriales ispG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS06430,iJN678.gcpE Bacteria 2GK2S@201174,4CYQB@85004,COG0821@1,COG0821@2 NA|NA|NA I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate NIBLCNGB_00037 326426.Bbr_0659 0.0 1130.2 Bifidobacteriales Bacteria 2I2GD@201174,4CZUD@85004,COG0657@1,COG0657@2 NA|NA|NA I acetylesterase activity NIBLCNGB_00038 326426.Bbr_0660 1e-128 466.1 Bifidobacteriales recO GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2GK81@201174,4CZCN@85004,COG1381@1,COG1381@2 NA|NA|NA L Involved in DNA repair and RecF pathway recombination NIBLCNGB_00039 326426.Bbr_0661 3.1e-155 554.3 Bifidobacteriales uppS GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 R06447,R09244,R09731 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 Bacteria 2GIXF@201174,4CZAR@85004,COG0020@1,COG0020@2 NA|NA|NA H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids NIBLCNGB_00040 326426.Bbr_0662 4.5e-135 487.3 Bifidobacteriales ytlD1 2.7.1.50 ko:K00878,ko:K15599 ko00730,ko01100,ko02010,map00730,map01100,map02010 M00127,M00442 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.17.3,3.A.1.17.6 Bacteria 2GKKZ@201174,4CZ9Q@85004,COG0600@1,COG0600@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component NIBLCNGB_00041 326426.Bbr_0663 5.2e-190 670.2 Bifidobacteriales ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 2HZ9T@201174,4CZ56@85004,COG0715@1,COG0715@2 NA|NA|NA P NMT1/THI5 like NIBLCNGB_00042 326426.Bbr_0664 4.8e-224 783.5 Bifidobacteriales Bacteria 2GNMB@201174,4CZ48@85004,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase class I and II NIBLCNGB_00043 326426.Bbr_0665 3.7e-140 504.2 Bifidobacteriales bioM ko:K16784,ko:K16786 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2I9PF@201174,4D04S@85004,COG1122@1,COG1122@2 NA|NA|NA P ATPases associated with a variety of cellular activities NIBLCNGB_00044 1437608.BBIA_1626 6.1e-19 100.1 Bifidobacteriales 2.8.2.22 ko:K01023 ko00000,ko01000 Bacteria 2A5FI@1,2I8X3@201174,30U5H@2,4D09F@85004 NA|NA|NA S Arylsulfotransferase Ig-like domain NIBLCNGB_00045 326426.Bbr_0666 0.0 1415.2 Bifidobacteriales Bacteria 2GNXR@201174,4CZXK@85004,COG1807@1,COG1807@2 NA|NA|NA M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family NIBLCNGB_00046 326426.Bbr_0667 0.0 2124.7 Bifidobacteriales Bacteria 2GWSR@201174,4CZ33@85004,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat NIBLCNGB_00047 326426.Bbr_0668 0.0 1805.0 Bifidobacteriales ligA GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 2GJUY@201174,4CZBC@85004,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA NIBLCNGB_00048 326426.Bbr_0669 3.3e-203 714.1 Bifidobacteriales mrp GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0040007,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K02612,ko:K03593,ko:K04488 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001,ko03029,ko03036 Bacteria 2GJUZ@201174,4CZDC@85004,COG0489@1,COG0489@2,COG2151@1,COG2151@2 NA|NA|NA D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP NIBLCNGB_00049 326426.Bbr_0670 2.3e-281 974.2 Bifidobacteriales glnA GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 2GMN1@201174,4CZNK@85004,COG0174@1,COG0174@2 NA|NA|NA E glutamine synthetase NIBLCNGB_00050 326426.Bbr_0671 6e-143 513.5 Bifidobacteriales Bacteria 2AUFS@1,2I87Z@201174,2ZBYU@2,4CYT8@85004 NA|NA|NA S Domain of unknown function (DUF4191) NIBLCNGB_00051 326426.Bbr_0672 4.2e-249 867.1 Bifidobacteriales lpdA 1.16.1.1,1.8.1.4 ko:K00382,ko:K00520 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GIXY@201174,4CZEI@85004,COG1249@1,COG1249@2 NA|NA|NA C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family NIBLCNGB_00052 216816.GS08_03265 6.9e-102 376.7 Bifidobacteriales GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 Bacteria 2AN86@1,2HWWU@201174,31D67@2,4CZZS@85004 NA|NA|NA S Protein of unknown function (DUF3043) NIBLCNGB_00053 326426.Bbr_0674 3.4e-258 897.1 Bifidobacteriales argE Bacteria 2GM84@201174,4CYZT@85004,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain NIBLCNGB_00054 326426.Bbr_0675 4e-107 394.0 Bifidobacteriales ykoE ko:K16925 M00582 ko00000,ko00002,ko02000 3.A.1.30 Bacteria 2IDAN@201174,4D00D@85004,COG4721@1,COG4721@2 NA|NA|NA S ABC-type cobalt transport system, permease component NIBLCNGB_00055 326426.Bbr_0676 1.2e-277 961.8 Bifidobacteriales ykoD ko:K01990,ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00254,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2GJ0M@201174,4CYZ6@85004,COG1122@1,COG1122@2 NA|NA|NA P ATPases associated with a variety of cellular activities NIBLCNGB_00056 326426.Bbr_0677 7.4e-164 583.2 Bifidobacteriales cbiQ ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2IDC9@201174,4CZM8@85004,COG0619@1,COG0619@2 NA|NA|NA P Cobalt transport protein NIBLCNGB_00057 326426.Bbr_0678 3e-159 567.8 Bifidobacteriales IV02_28330 2.1.1.185,2.1.1.34 ko:K00556,ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 2GJI6@201174,4CYZQ@85004,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family NIBLCNGB_00058 326426.Bbr_0679 1.3e-201 708.8 Bifidobacteriales pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GJGG@201174,4CZ78@85004,COG0016@1,COG0016@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily NIBLCNGB_00059 326426.Bbr_0680 0.0 1756.1 Bifidobacteriales pheT GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GMFD@201174,4CYUM@85004,COG0072@1,COG0072@2,COG0073@1,COG0073@2 NA|NA|NA J Phenylalanyl-tRNA synthetase beta NIBLCNGB_00060 326426.Bbr_0681 9.3e-97 359.8 Bifidobacteriales Bacteria 2AHAX@1,2IPJ5@201174,317M8@2,4D11M@85004 NA|NA|NA NIBLCNGB_00061 326426.Bbr_0682 6.8e-201 706.4 Bifidobacteriales argC GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKQK@201174,4CZNC@85004,COG0002@1,COG0002@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde NIBLCNGB_00062 326426.Bbr_0683 2e-211 741.5 Bifidobacteriales argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 ko:K00620,ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIW0@201174,4CZQQ@85004,COG1364@1,COG1364@2 NA|NA|NA E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate NIBLCNGB_00063 326426.Bbr_0684 2.4e-178 631.3 Bifidobacteriales argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS10565,iJN678.argB,iLJ478.TM1784 Bacteria 2GKDS@201174,4CYYX@85004,COG0548@1,COG0548@2 NA|NA|NA E Belongs to the acetylglutamate kinase family. ArgB subfamily NIBLCNGB_00064 326426.Bbr_0685 3.9e-248 863.6 Bifidobacteriales argD GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GKE9@201174,4CZGW@85004,COG4992@1,COG4992@2 NA|NA|NA E Aminotransferase class-III NIBLCNGB_00065 326426.Bbr_0686 3.9e-184 650.6 Bifidobacteriales argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ6H@201174,4CZGN@85004,COG0078@1,COG0078@2 NA|NA|NA E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline NIBLCNGB_00066 326426.Bbr_0687 1e-82 312.8 Bifidobacteriales argR GO:0000820,GO:0000821,GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006259,GO:0006310,GO:0006355,GO:0006520,GO:0006521,GO:0006525,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016043,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0022607,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031333,GO:0031334,GO:0031406,GO:0032991,GO:0032993,GO:0033238,GO:0033241,GO:0034214,GO:0034618,GO:0034641,GO:0036094,GO:0042150,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043254,GO:0043436,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051259,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140110,GO:1900079,GO:1900081,GO:1901360,GO:1901363,GO:1901564,GO:1901605,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2000144,GO:2000282,GO:2001141 ko:K03402 ko00000,ko03000 Bacteria 2GKA5@201174,4D0VM@85004,COG1438@1,COG1438@2 NA|NA|NA K Regulates arginine biosynthesis genes NIBLCNGB_00067 326426.Bbr_0688 1.2e-238 832.0 Bifidobacteriales argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 iNJ661.Rv1658 Bacteria 2GK96@201174,4CZ2R@85004,COG0137@1,COG0137@2 NA|NA|NA E Belongs to the argininosuccinate synthase family. Type 1 subfamily NIBLCNGB_00068 326426.Bbr_0692 3e-281 973.8 Bifidobacteriales argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.argH Bacteria 2GJ2A@201174,4CZ50@85004,COG0165@1,COG0165@2 NA|NA|NA E argininosuccinate lyase NIBLCNGB_00069 326426.Bbr_0693 1.2e-28 131.7 Bifidobacteriales thiS 2.8.1.10 ko:K03149,ko:K03154 ko00730,ko01100,ko04122,map00730,map01100,map04122 R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 Bacteria 2GSKM@201174,4D1GS@85004,COG2104@1,COG2104@2 NA|NA|NA H ThiS family NIBLCNGB_00070 326426.Bbr_0694 4e-156 557.4 Bifidobacteriales thiG GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c45060,iECO26_1355.ECO26_5099,ic_1306.c4947 Bacteria 2GM62@201174,4CZ4A@85004,COG2022@1,COG2022@2 NA|NA|NA H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S NIBLCNGB_00071 326426.Bbr_0695 1.3e-145 522.3 Bifidobacteriales moeB 2.7.7.80 ko:K21029 ko04122,map04122 R07459 RC00043 ko00000,ko00001,ko01000 Bacteria 2GJB6@201174,4D06G@85004,COG0476@1,COG0476@2 NA|NA|NA H ThiF family NIBLCNGB_00072 326426.Bbr_0696 1.5e-64 251.9 Bifidobacteriales M1-798 ko:K03892 ko00000,ko03000 Bacteria 2ISA2@201174,4D2SX@85004,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain NIBLCNGB_00073 326426.Bbr_0697 1e-101 375.9 Bifidobacteriales 6.1.1.14 ko:K01879,ko:K06950 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2IFXP@201174,4D0P2@85004,COG1418@1,COG1418@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. NIBLCNGB_00074 326426.Bbr_0698 3.9e-139 500.7 Bifidobacteriales Bacteria 2IA3M@201174,4CZY7@85004,COG4905@1,COG4905@2 NA|NA|NA S Putative ABC-transporter type IV NIBLCNGB_00075 326426.Bbr_0700 2.6e-255 887.5 Bifidobacteriales tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2GJPR@201174,4CZKG@85004,COG0162@1,COG0162@2 NA|NA|NA J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) NIBLCNGB_00076 326426.Bbr_0701 5.8e-140 504.6 Bifidobacteriales Bacteria 2GKX5@201174,4CYXN@85004,COG0457@1,COG0457@2 NA|NA|NA L Tetratricopeptide repeat NIBLCNGB_00077 326426.Bbr_0702 7.8e-199 699.5 Bifidobacteriales yutF GO:0000121,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030145,GO:0042578,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0046434,GO:0046475,GO:0046486,GO:0046503,GO:0046872,GO:0046914,GO:0046983,GO:0050897,GO:0071704,GO:1901575 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 R03024 RC00151 ko00000,ko00001,ko01000 Bacteria 2GK7V@201174,4CZ1Z@85004,COG0647@1,COG0647@2 NA|NA|NA G Haloacid dehalogenase-like hydrolase NIBLCNGB_00079 326426.Bbr_0703 1e-139 502.7 Bifidobacteriales tlyA GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 ko:K06442 ko00000,ko01000,ko03009 Bacteria 2GJVT@201174,4CZSS@85004,COG1189@1,COG1189@2 NA|NA|NA J Ribosomal RNA large subunit methyltransferase J NIBLCNGB_00080 326426.Bbr_0704 4.7e-96 357.5 Bifidobacteriales Bacteria 2B0CX@1,2GR13@201174,31SQ3@2,4D1JN@85004 NA|NA|NA NIBLCNGB_00081 216816.GS08_03410 3.3e-46 190.7 Bifidobacteriales trkA ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 2IA09@201174,4CZVT@85004,COG0569@1,COG0569@2 NA|NA|NA P TrkA-N domain NIBLCNGB_00082 1437610.BREU_1038 8.3e-12 75.1 Bifidobacteriales trkB ko:K03498 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 2GKKS@201174,4CZH7@85004,COG0168@1,COG0168@2 NA|NA|NA P Cation transport protein NIBLCNGB_00083 326426.Bbr_0707 3.7e-182 644.0 Bifidobacteriales nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 2GKM2@201174,4CYZ0@85004,COG0061@1,COG0061@2 NA|NA|NA H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP NIBLCNGB_00084 326426.Bbr_0708 0.0 1114.4 Bifidobacteriales recN GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0030312,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 ko:K03631,ko:K13582 ko04112,map04112 ko00000,ko00001,ko03400 Bacteria 2GIVG@201174,4CYYF@85004,COG0497@1,COG0497@2 NA|NA|NA L May be involved in recombinational repair of damaged DNA NIBLCNGB_00085 326426.Bbr_0709 7.7e-120 436.4 Bifidobacteriales Bacteria 2I362@201174,4CZ8D@85004,COG0637@1,COG0637@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase NIBLCNGB_00086 1437609.BCAL_0838 2.1e-56 225.3 Bifidobacteriales Bacteria 2HZK6@201174,4D0RS@85004,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain NIBLCNGB_00087 326426.Bbr_0711 4.8e-58 230.3 Bifidobacteriales ko:K07978,ko:K07979 ko00000,ko03000 Bacteria 2IQEW@201174,4D152@85004,COG1725@1,COG1725@2 NA|NA|NA K helix_turn_helix gluconate operon transcriptional repressor NIBLCNGB_00088 326426.Bbr_0712 1.1e-172 612.5 Bifidobacteriales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GRE8@201174,4CZBH@85004,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities NIBLCNGB_00089 326426.Bbr_0713 1.7e-120 438.7 Bifidobacteriales Bacteria 2ARYF@1,2IK3T@201174,31HAF@2,4D0YH@85004 NA|NA|NA S ABC-2 family transporter protein NIBLCNGB_00090 326426.Bbr_0714 4.8e-107 394.0 Bifidobacteriales Bacteria 29MAK@1,2HAKE@201174,3088B@2,4D2I1@85004 NA|NA|NA NIBLCNGB_00091 326426.Bbr_0715 1.4e-281 974.9 Bifidobacteriales thrC 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS16355,iIT341.HP0098 Bacteria 2GIRY@201174,4CYS0@85004,COG0498@1,COG0498@2 NA|NA|NA E Threonine synthase N terminus NIBLCNGB_00092 326426.Bbr_0716 2.3e-232 811.2 Bifidobacteriales proA GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0293,iNJ661.Rv2427c,iYO844.BSU13130 Bacteria 2GISA@201174,4CZ2H@85004,COG0014@1,COG0014@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate NIBLCNGB_00093 326426.Bbr_0717 2.7e-97 361.3 Bifidobacteriales Bacteria 2A13J@1,2GKGD@201174,30P9F@2,4D0QR@85004 NA|NA|NA NIBLCNGB_00094 326426.Bbr_0718 3.2e-138 497.7 Bifidobacteriales nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2GMFZ@201174,4CZ82@85004,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) NIBLCNGB_00095 216816.GS08_03510 5.7e-130 470.7 Bifidobacteriales ybbD 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM43@201174,4CZ6R@85004,COG1472@1,COG1472@2 NA|NA|NA G Glycosyl hydrolase family 3 N-terminal domain protein NIBLCNGB_00096 326426.Bbr_0720 0.0 1854.0 Bifidobacteriales GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K09118 ko00000 Bacteria 2GMP3@201174,4CYW1@85004,COG1615@1,COG1615@2 NA|NA|NA S Uncharacterised protein family (UPF0182) NIBLCNGB_00097 326426.Bbr_0721 4.1e-93 347.4 Bifidobacteriales 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 Bacteria 2HZCB@201174,4CZQI@85004,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase (GNAT) domain NIBLCNGB_00098 326426.Bbr_0722 1.5e-114 418.7 Bifidobacteriales pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 2GKCV@201174,4CZBE@85004,COG0193@1,COG0193@2 NA|NA|NA J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis NIBLCNGB_00099 326426.Bbr_0723 0.0 2336.2 Bifidobacteriales mfd ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJ42@201174,4CZ8X@85004,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site NIBLCNGB_00100 326426.Bbr_0724 2.1e-179 634.8 Bifidobacteriales 1.1.1.65 ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 R01708 RC00116 ko00000,ko00001,ko01000 Bacteria 2GJ6R@201174,4CZ9P@85004,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family NIBLCNGB_00101 326426.Bbr_0725 1.5e-244 851.7 Bifidobacteriales eno 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 2GJAY@201174,4CYT3@85004,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis NIBLCNGB_00102 326426.Bbr_0726 9.5e-69 266.5 Bifidobacteriales divIC ko:K05589,ko:K13052 ko00000,ko03036 Bacteria 2IR5G@201174,4D0SS@85004,COG2919@1,COG2919@2 NA|NA|NA D Septum formation initiator NIBLCNGB_00103 326426.Bbr_0727 8.2e-102 376.3 Bifidobacteriales ppx2 3.6.1.11,3.6.1.40 ko:K01524,ko:K09009 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 2I8CS@201174,4CZQX@85004,COG1507@1,COG1507@2 NA|NA|NA S Protein of unknown function (DUF501) NIBLCNGB_00104 326426.Bbr_0728 2.2e-182 644.8 Bifidobacteriales ppx GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 2GJBN@201174,4CZCS@85004,COG0248@1,COG0248@2 NA|NA|NA FP Ppx/GppA phosphatase family NIBLCNGB_00106 326426.Bbr_0729 2.9e-94 351.3 Bifidobacteriales Bacteria 2ASIR@1,2IHD9@201174,31HZA@2,4D0QP@85004 NA|NA|NA NIBLCNGB_00107 326426.Bbr_0730 1.2e-282 978.4 Bifidobacteriales sdaA 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 2GJPA@201174,4CZ6I@85004,COG1760@1,COG1760@2 NA|NA|NA E Serine dehydratase alpha chain NIBLCNGB_00108 326426.Bbr_0731 1.4e-74 285.4 Bifidobacteriales fkbP 5.2.1.8 ko:K01802 ko00000,ko01000 Bacteria 2GJK2@201174,4D0V6@85004,COG0545@1,COG0545@2 NA|NA|NA G Peptidyl-prolyl cis-trans NIBLCNGB_00109 326426.Bbr_0732 4.4e-80 303.9 Bifidobacteriales greA GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K03624 ko00000,ko03021 Bacteria 2GNZV@201174,4D0QM@85004,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides NIBLCNGB_00110 326426.Bbr_0733 1.4e-146 525.8 Bifidobacteriales yplQ ko:K11068 ko00000,ko02042 Bacteria 2GJGQ@201174,4CZGT@85004,COG1272@1,COG1272@2 NA|NA|NA S Haemolysin-III related NIBLCNGB_00111 326426.Bbr_0734 7.1e-278 962.6 Bifidobacteriales pdtaS GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 ko:K00936 M00839 ko00000,ko00002,ko01000,ko01001,ko02022 Bacteria 2GKMP@201174,4CYV1@85004,COG3920@1,COG3920@2 NA|NA|NA T ATPase histidine kinase DNA gyrase B HSP90 domain protein NIBLCNGB_00112 326426.Bbr_0735 4.9e-47 193.4 Bifidobacteriales whiB GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K18955 ko00000,ko03000 Bacteria 2DMIE@1,2IQCG@201174,32RSG@2,4D11W@85004 NA|NA|NA K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA NIBLCNGB_00113 326426.Bbr_0736 0.0 1120.1 Bifidobacteriales ko:K03466 ko00000,ko03036 3.A.12 Bacteria 2GJBR@201174,4CYU3@85004,COG1674@1,COG1674@2 NA|NA|NA D FtsK/SpoIIIE family NIBLCNGB_00114 326426.Bbr_0737 5.5e-205 720.3 Bifidobacteriales Bacteria 2GJJJ@201174,4CYQY@85004,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-related transcriptional attenuator domain NIBLCNGB_00115 326426.Bbr_0738 1.8e-55 221.5 Bifidobacteriales whiB ko:K18955 ko00000,ko03000 Bacteria 2CC1Y@1,2IQ4Q@201174,32RUK@2,4D12I@85004 NA|NA|NA K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA NIBLCNGB_00116 326426.Bbr_0739 0.0 1931.0 Bifidobacteriales Bacteria 2I2FX@201174,4CYVM@85004,COG1216@1,COG1216@2,COG5617@1,COG5617@2 NA|NA|NA S Glycosyl transferase, family 2 NIBLCNGB_00117 326426.Bbr_0740 1.4e-257 895.2 Bifidobacteriales Bacteria 2EC47@1,2I2HY@201174,33QBB@2,4D2VU@85004 NA|NA|NA NIBLCNGB_00118 326426.Bbr_0741 6.3e-78 296.6 Bifidobacteriales MA20_43655 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 2IS6W@201174,4D0YK@85004,COG3824@1,COG3824@2 NA|NA|NA S Zincin-like metallopeptidase NIBLCNGB_00119 326426.Bbr_0742 1.1e-144 519.2 Bifidobacteriales cof 5.2.1.8 ko:K01802 ko00000,ko01000 Bacteria 2HZD0@201174,4CZ4N@85004,COG0561@1,COG0561@2 NA|NA|NA T Eukaryotic phosphomannomutase NIBLCNGB_00120 326426.Bbr_0743 7.1e-105 386.7 Bifidobacteriales ctsW ko:K02242 M00429 ko00000,ko00002,ko02044 Bacteria 2I9PA@201174,4D11A@85004,COG1040@1,COG1040@2 NA|NA|NA S Phosphoribosyl transferase domain NIBLCNGB_00121 326426.Bbr_0744 4.9e-196 690.3 Bifidobacteriales Bacteria 2GIX7@201174,4CZNA@85004,COG5002@1,COG5002@2 NA|NA|NA T ATPase histidine kinase DNA gyrase B HSP90 domain protein NIBLCNGB_00122 326426.Bbr_0745 1e-128 466.1 Bifidobacteriales Bacteria 2GJE6@201174,4CZS5@85004,COG0745@1,COG0745@2 NA|NA|NA T Response regulator receiver domain protein NIBLCNGB_00123 326426.Bbr_0746 0.0 1550.8 Bifidobacteriales glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13 Bacteria 2GJ5C@201174,4CZMD@85004,COG0296@1,COG0296@2 NA|NA|NA G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position NIBLCNGB_00124 326426.Bbr_0747 2.1e-100 371.7 Bifidobacteriales carD GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 ko:K07736 ko00000,ko03000 Bacteria 2GKSU@201174,4CZXD@85004,COG1329@1,COG1329@2 NA|NA|NA K CarD-like/TRCF domain NIBLCNGB_00125 326426.Bbr_0748 1.1e-87 329.3 Bifidobacteriales ispF GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008685,GO:0009058,GO:0009987,GO:0016114,GO:0016829,GO:0016849,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0051483,GO:0071704,GO:1901576 2.1.1.228,2.7.7.60,4.6.1.12 ko:K00554,ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05633,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 iNJ661.Rv3581c Bacteria 2II8H@201174,4D0X6@85004,COG0245@1,COG0245@2 NA|NA|NA H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) NIBLCNGB_00126 326426.Bbr_0749 9.8e-136 489.6 Bifidobacteriales znuB ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 2GJ7H@201174,4CYTG@85004,COG1108@1,COG1108@2 NA|NA|NA U ABC 3 transport family NIBLCNGB_00127 326426.Bbr_0750 3.8e-162 577.4 Bifidobacteriales znuC ko:K02074,ko:K09817 ko02010,map02010 M00242,M00244 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 2GP3A@201174,4CZEV@85004,COG1121@1,COG1121@2 NA|NA|NA P ATPases associated with a variety of cellular activities NIBLCNGB_00128 326426.Bbr_0751 8e-184 649.8 Bifidobacteriales ko:K02077 M00244 ko00000,ko00002,ko02000 3.A.1.15 Bacteria 2GM1K@201174,4CZ99@85004,COG0803@1,COG0803@2 NA|NA|NA P Zinc-uptake complex component A periplasmic NIBLCNGB_00129 326426.Bbr_0752 7.6e-163 579.7 Bifidobacteriales folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJZS@201174,4CZ53@85004,COG0190@1,COG0190@2 NA|NA|NA F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate NIBLCNGB_00130 326426.Bbr_0753 3.2e-254 884.0 Bifidobacteriales rpsA ko:K02945 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJAK@201174,4CZ6S@85004,COG0539@1,COG0539@2 NA|NA|NA J Ribosomal protein S1 NIBLCNGB_00131 326426.Bbr_0754 3e-114 417.9 Bifidobacteriales coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN96@201174,4D0PG@85004,COG0237@1,COG0237@2 NA|NA|NA H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A NIBLCNGB_00132 326426.Bbr_0755 0.0 1382.5 Bifidobacteriales uvrB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K03702,ko:K08999 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2GJ03@201174,4CZR0@85004,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage NIBLCNGB_00133 326426.Bbr_0756 1.5e-175 622.1 Bifidobacteriales terC ko:K05794 ko00000 Bacteria 2GIWU@201174,4CYW2@85004,COG0861@1,COG0861@2 NA|NA|NA P Integral membrane protein, TerC family NIBLCNGB_00134 326426.Bbr_0757 6e-274 949.5 Bifidobacteriales pyk GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 e_coli_core.b1854,iAF1260.b1854,iB21_1397.B21_01813,iBWG_1329.BWG_1668,iEC042_1314.EC042_2021,iECBD_1354.ECBD_1784,iECB_1328.ECB_01825,iECDH10B_1368.ECDH10B_1995,iECDH1ME8569_1439.ECDH1ME8569_1801,iECD_1391.ECD_01825,iECO103_1326.ECO103_2044,iECO111_1330.ECO111_2362,iECO26_1355.ECO26_2692,iECUMN_1333.ECUMN_2152,iETEC_1333.ETEC_1887,iEcDH1_1363.EcDH1_1786,iEcE24377_1341.EcE24377A_2084,iEcHS_1320.EcHS_A1947,iEcSMS35_1347.EcSMS35_1332,iEcolC_1368.EcolC_1778,iG2583_1286.G2583_2306,iJO1366.b1854,iJR904.b1854,iSBO_1134.SBO_1162,iSSON_1240.SSON_1294,iSbBS512_1146.SbBS512_E2130,iUMNK88_1353.UMNK88_2326,iY75_1357.Y75_RS09740 Bacteria 2GJY8@201174,4CZA8@85004,COG0469@1,COG0469@2 NA|NA|NA G Pyruvate kinase NIBLCNGB_00135 326426.Bbr_0758 1.1e-109 402.5 Bifidobacteriales aspA 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 Bacteria 2HEH8@201174,4CZD0@85004,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain NIBLCNGB_00137 326426.Bbr_0759 2.8e-124 451.4 Bifidobacteriales pdtaR GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 ko:K22010 M00839 ko00000,ko00002,ko02022 Bacteria 2GK7T@201174,4CYS7@85004,COG3707@1,COG3707@2 NA|NA|NA T Response regulator receiver domain protein NIBLCNGB_00138 326426.Bbr_0760 0.0 1865.1 Bifidobacteriales polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 2GJY2@201174,4CYVK@85004,COG0258@1,COG0258@2,COG0749@1,COG0749@2 NA|NA|NA L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity NIBLCNGB_00139 326426.Bbr_0761 3.3e-177 627.5 Bifidobacteriales yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.16 ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKHZ@201174,4CYXC@85004,COG0327@1,COG0327@2 NA|NA|NA L NIF3 (NGG1p interacting factor 3) NIBLCNGB_00140 326426.Bbr_0762 4e-127 460.7 Bifidobacteriales 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 Bacteria 2IIY0@201174,4D0P8@85004,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain NIBLCNGB_00141 326426.Bbr_0763 0.0 1438.7 Bifidobacteriales glgX 3.2.1.68 ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11261 ko00000,ko00001,ko00002,ko01000 CBM48,GH13 Bacteria 2GJ00@201174,4CZGR@85004,COG1523@1,COG1523@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family NIBLCNGB_00142 216816.GS08_03780 6.4e-25 119.4 Bacteria zntR GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 Bacteria COG0789@1,COG0789@2 NA|NA|NA K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding NIBLCNGB_00143 702459.BBPR_0984 1.1e-89 335.9 Bifidobacteriales Bacteria 2IGPZ@201174,4D0N7@85004,COG1476@1,COG1476@2 NA|NA|NA K Putative zinc ribbon domain NIBLCNGB_00144 326426.Bbr_0766 2.1e-125 454.9 Bifidobacteriales Bacteria 2GN4K@201174,4D08M@85004,COG4832@1,COG4832@2 NA|NA|NA S GyrI-like small molecule binding domain NIBLCNGB_00145 216816.GS08_03800 4.6e-105 387.1 Bifidobacteriales tag 3.2.2.20 ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2IFH0@201174,4D0ZA@85004,COG2818@1,COG2818@2 NA|NA|NA L Methyladenine glycosylase NIBLCNGB_00147 908340.HMPREF9406_0789 2.3e-143 515.0 Clostridiaceae Bacteria 1TSRV@1239,248P6@186801,36FST@31979,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region NIBLCNGB_00148 665950.HMPREF1025_00451 4.1e-22 110.2 unclassified Lachnospiraceae Bacteria 1VBGF@1239,24NRM@186801,27SHV@186928,COG0582@1,COG0582@2 NA|NA|NA L viral genome integration into host DNA NIBLCNGB_00149 908340.HMPREF9406_3382 3.3e-36 157.1 Clostridia Bacteria 1V8RM@1239,24PX5@186801,2BPZN@1,32ITP@2 NA|NA|NA S Helix-turn-helix domain NIBLCNGB_00150 1415166.NONO_c60450 2.9e-13 82.4 Bacteria Bacteria 2DM0C@1,314VX@2 NA|NA|NA NIBLCNGB_00151 158787.BSCA_0889 0.0 1319.7 Bifidobacteriales dam 2.1.1.72 ko:K06223,ko:K07318 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 Bacteria 2I9YW@201174,4D0ZX@85004,COG0338@1,COG0338@2,COG3392@1,COG3392@2 NA|NA|NA L DNA binding domain with preference for A/T rich regions NIBLCNGB_00152 158787.BSCA_0888 1.1e-282 978.8 Bifidobacteriales Bacteria 2ICSJ@201174,4D1QI@85004,COG1578@1,COG1578@2 NA|NA|NA S AlwI restriction endonuclease NIBLCNGB_00153 566552.BIFCAT_01007 2e-35 154.8 Bifidobacteriales Bacteria 2A804@1,2IMWR@201174,30X0B@2,4D12R@85004 NA|NA|NA NIBLCNGB_00154 1437608.BBIA_1423 3e-143 515.0 Bifidobacteriales ko:K07273 ko00000 Bacteria 2I2GA@201174,4D07F@85004,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 NIBLCNGB_00155 1437609.BCAL_1734 3.4e-30 137.9 Bifidobacteriales Bacteria 2B5DY@1,2H0D8@201174,31Y8E@2,4D1NY@85004 NA|NA|NA NIBLCNGB_00156 1437609.BCAL_1735 7.8e-55 220.7 Bifidobacteriales Bacteria 2GVUQ@201174,4D1JT@85004,COG2023@1,COG2023@2 NA|NA|NA J tRNA 5'-leader removal NIBLCNGB_00157 1688.BCUN_0910 2.3e-146 525.4 Bifidobacteriales 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 2IC00@201174,4D0TE@85004,COG0515@1,COG0515@2,COG4271@1,COG4271@2 NA|NA|NA KLT Protein tyrosine kinase NIBLCNGB_00159 326426.Bbr_0769 1.9e-214 751.5 Bifidobacteriales ykiI Bacteria 2DSXT@1,2GKR7@201174,32UTZ@2,4CZBW@85004 NA|NA|NA NIBLCNGB_00160 326426.Bbr_0770 7.8e-252 875.9 Bifidobacteriales aroA GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJKX@201174,4CZBG@85004,COG0128@1,COG0128@2 NA|NA|NA E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate NIBLCNGB_00161 326426.Bbr_0771 1.7e-232 811.6 Bifidobacteriales ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.7.2.1,2.7.2.15 ko:K00925,ko:K19697 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1034,iIT341.HP0903m,iNJ661.Rv0409 Bacteria 2GJAW@201174,4CZ7V@85004,COG0282@1,COG0282@2 NA|NA|NA H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction NIBLCNGB_00162 326426.Bbr_0772 0.0 1090.5 Bifidobacteriales pta GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0006082,GO:0006083,GO:0006950,GO:0008150,GO:0008152,GO:0008959,GO:0009058,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016053,GO:0016407,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0030145,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0046914,GO:0050182,GO:0050896,GO:0055114,GO:0071704,GO:0072330,GO:1901576 1.1.1.40,2.3.1.19,2.3.1.8,3.6.3.21 ko:K00029,ko:K00625,ko:K00634,ko:K02028,ko:K04020,ko:K13788 ko00430,ko00620,ko00640,ko00650,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00650,map00680,map00710,map00720,map01100,map01120,map01200 M00169,M00172,M00236,M00357,M00579 R00216,R00230,R00921,R01174 RC00004,RC00105,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 iAF987.Gmet_1035,iAF987.Gmet_1637,iAF987.Gmet_2098,iE2348C_1286.E2348C_2692,iSB619.SA_RS03155,iYO844.BSU24090 Bacteria 2GJ5U@201174,4CZE6@85004,COG0280@1,COG0280@2 NA|NA|NA C phosphate acetyltransferase NIBLCNGB_00164 326426.Bbr_0773 1.9e-192 678.3 Bifidobacteriales prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ9S@201174,4CYRD@85004,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) NIBLCNGB_00165 326426.Bbr_0774 0.0 1200.7 Bifidobacteriales XK27_09800 Bacteria 2GKI5@201174,4D0BY@85004,COG1835@1,COG1835@2 NA|NA|NA I Psort location CytoplasmicMembrane, score 9.99 NIBLCNGB_00166 326426.Bbr_0775 1.8e-300 1037.7 Bifidobacteriales guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 iJN746.PP_1032,iLJ478.TM1820,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833 Bacteria 2GM09@201174,4CZC3@85004,COG0518@1,COG0518@2,COG0519@1,COG0519@2 NA|NA|NA F Catalyzes the synthesis of GMP from XMP NIBLCNGB_00167 326426.Bbr_0776 0.0 1711.4 Bifidobacteriales xfp GO:0003674,GO:0003824,GO:0008150,GO:0009758 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 Bacteria 2GN27@201174,4CZT5@85004,COG3957@1,COG3957@2 NA|NA|NA G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase NIBLCNGB_00168 326426.Bbr_0777 3.5e-263 913.7 Bifidobacteriales glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042,ko:K11528,ko:K16203 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000,ko01002 3.A.1.5.2 iJN678.glmU,iLJ478.TM1629 Bacteria 2GJS1@201174,4CZ4C@85004,COG1207@1,COG1207@2 NA|NA|NA M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain NIBLCNGB_00169 326426.Bbr_0778 6.5e-66 256.5 Bifidobacteriales rsfS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 ko:K00969,ko:K09710 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 2IKZ3@201174,4D11U@85004,COG0799@1,COG0799@2 NA|NA|NA J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation NIBLCNGB_00170 326426.Bbr_0779 2.7e-134 484.6 Bifidobacteriales 3.1.3.85 ko:K22306 ko00000,ko01000 Bacteria 2GJYU@201174,4CYXK@85004,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family NIBLCNGB_00173 326426.Bbr_0780 5.6e-158 563.5 Bifidobacteriales Bacteria 2HZBH@201174,4CZIQ@85004,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase NIBLCNGB_00174 326426.Bbr_0781 2.5e-178 631.3 Bifidobacteriales metQ ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 2GMNI@201174,4CZNB@85004,COG1464@1,COG1464@2 NA|NA|NA P NLPA lipoprotein NIBLCNGB_00175 326426.Bbr_0782 3.2e-220 770.8 Bifidobacteriales metN ko:K02071 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 2GJ9P@201174,4CZYI@85004,COG1135@1,COG1135@2 NA|NA|NA P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system NIBLCNGB_00176 326426.Bbr_0783 7.4e-113 413.3 Bifidobacteriales metI ko:K02072 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 2GY65@201174,4CZWG@85004,COG2011@1,COG2011@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component NIBLCNGB_00177 326426.Bbr_0784 3.7e-226 790.4 Bifidobacteriales ko:K01436 ko00000,ko01000,ko01002 Bacteria 2GK05@201174,4CZC6@85004,COG1473@1,COG1473@2 NA|NA|NA S Peptidase dimerisation domain NIBLCNGB_00178 326426.Bbr_0785 0.0 1128.6 Bifidobacteriales nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK2C@201174,4CZ14@85004,COG0171@1,COG0171@2,COG0388@1,COG0388@2 NA|NA|NA H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source NIBLCNGB_00179 326426.Bbr_0786 3.8e-37 160.2 Bifidobacteriales Bacteria 2EHMB@1,2HZRX@201174,33BD3@2,4D1G1@85004 NA|NA|NA NIBLCNGB_00180 326426.Bbr_0787 0.0 1627.1 Bifidobacteriales pflB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006629,GO:0006631,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016020,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017144,GO:0019541,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0043875,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0070689,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 iECH74115_1262.ECH74115_1064,iECIAI39_1322.ECIAI39_2245,iECSP_1301.ECSP_1007,iECs_1301.ECs0986,iEcSMS35_1347.EcSMS35_2218,iEcSMS35_1347.EcSMS35_3410,iG2583_1286.G2583_1138,iSDY_1059.SDY_2358,iZ_1308.Z1248 Bacteria 2GTTT@201174,4CZ59@85004,COG1882@1,COG1882@2 NA|NA|NA C Pyruvate formate lyase-like NIBLCNGB_00181 326426.Bbr_0788 8.7e-175 619.4 Bifidobacteriales pflA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0018307,GO:0019538,GO:0033554,GO:0036211,GO:0043170,GO:0043364,GO:0043365,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070283,GO:0071704,GO:1901564 1.97.1.4 ko:K04069 R04710 ko00000,ko01000 iECOK1_1307.ECOK1_0925,iEcE24377_1341.EcE24377A_0980,iEcSMS35_1347.EcSMS35_2219,iYL1228.KPN_00930 Bacteria 2GN2B@201174,4CZ5Y@85004,COG1180@1,COG1180@2 NA|NA|NA C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine NIBLCNGB_00182 326426.Bbr_0789 1.4e-118 432.2 Bifidobacteriales Bacteria 2B58P@1,2HZMM@201174,31Y2Q@2,4D0Y9@85004 NA|NA|NA S Protein of unknown function (DUF3000) NIBLCNGB_00183 326426.Bbr_0790 3.4e-252 877.1 Bifidobacteriales rnd 3.1.13.5 ko:K03684 ko00000,ko01000,ko03016 Bacteria 2GKNM@201174,4CYUV@85004,COG0349@1,COG0349@2 NA|NA|NA J 3'-5' exonuclease NIBLCNGB_00184 326426.Bbr_0791 4.4e-234 817.0 Bifidobacteriales tig GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 ko:K03545 ko00000 Bacteria 2GJIG@201174,4CZ6P@85004,COG0544@1,COG0544@2 NA|NA|NA D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase NIBLCNGB_00185 326426.Bbr_0792 8.2e-244 849.4 Bifidobacteriales clcA_2 ko:K03281 ko00000 2.A.49 Bacteria 2GPPN@201174,4CZPX@85004,COG0038@1,COG0038@2 NA|NA|NA P Voltage gated chloride channel NIBLCNGB_00186 326426.Bbr_0793 2e-59 235.0 Bifidobacteriales Bacteria 2A3Y6@1,2IM76@201174,30SGI@2,4D10Z@85004 NA|NA|NA NIBLCNGB_00187 326426.Bbr_0794 6.5e-116 423.3 Bifidobacteriales clpP 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 2GK5C@201174,4CYUU@85004,COG0740@1,COG0740@2 NA|NA|NA O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins NIBLCNGB_00188 326426.Bbr_0795 7.3e-121 439.9 Bifidobacteriales clpP GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 2GKNK@201174,4CZVF@85004,COG0740@1,COG0740@2 NA|NA|NA O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins NIBLCNGB_00189 326426.Bbr_0796 8e-252 875.9 Bifidobacteriales clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 2GJXQ@201174,4CYT6@85004,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP NIBLCNGB_00192 326426.Bbr_0797 1.3e-242 845.1 Bifidobacteriales patB 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 Bacteria 2GJFQ@201174,4CZFH@85004,COG1168@1,COG1168@2 NA|NA|NA E Aminotransferase, class I II NIBLCNGB_00193 326426.Bbr_0798 1.3e-238 832.0 Bifidobacteriales nhaA ko:K03313 ko00000,ko02000 2.A.33.1 Bacteria 2GKIK@201174,4CZES@85004,COG3004@1,COG3004@2 NA|NA|NA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons NIBLCNGB_00194 326426.Bbr_0799 1.6e-168 598.6 Bifidobacteriales fmt2 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 2GKJH@201174,4CZ8R@85004,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family NIBLCNGB_00195 326426.Bbr_0800 1.9e-113 415.2 Bifidobacteriales safC GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 Bacteria 2HXV7@201174,4CZZN@85004,COG4122@1,COG4122@2 NA|NA|NA S O-methyltransferase NIBLCNGB_00196 326426.Bbr_0801 1.1e-183 649.0 Bifidobacteriales sdhB GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0022904,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 e_coli_core.b0724,iAF1260.b0724,iBWG_1329.BWG_0583,iEC042_1314.EC042_0742,iECDH10B_1368.ECDH10B_0791,iECDH1ME8569_1439.ECDH1ME8569_0683,iECUMN_1333.ECUMN_0802,iEcDH1_1363.EcDH1_2911,iJO1366.b0724,iJR904.b0724,iY75_1357.Y75_RS03765 Bacteria 2GP9C@201174,4CZWJ@85004,COG0479@1,COG0479@2 NA|NA|NA C 4Fe-4S dicluster domain NIBLCNGB_00197 326426.Bbr_0802 0.0 1220.3 Bifidobacteriales sdhA GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071704,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0072350,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 iE2348C_1286.E2348C_0603,iJN746.PP_4191,iPC815.YPO1111 Bacteria 2GJ45@201174,4CYT5@85004,COG1053@1,COG1053@2 NA|NA|NA C Succinate dehydrogenase flavoprotein subunit NIBLCNGB_00198 326426.Bbr_0803 0.0 1090.1 Bifidobacteriales dprA 5.99.1.2 ko:K03168,ko:K04096 ko00000,ko01000,ko03032,ko03400 Bacteria 2GKDA@201174,4CYVW@85004,COG0758@1,COG0758@2 NA|NA|NA LU DNA recombination-mediator protein A NIBLCNGB_00199 326426.Bbr_0804 3.4e-291 1006.9 Bifidobacteriales comM ko:K07391 ko00000 Bacteria 2GJIQ@201174,4CYUB@85004,COG0606@1,COG0606@2 NA|NA|NA O Magnesium chelatase, subunit ChlI C-terminal NIBLCNGB_00200 326426.Bbr_0805 8.3e-75 286.2 Bifidobacteriales yraN ko:K07460 ko00000 Bacteria 2IQ3X@201174,4D191@85004,COG0792@1,COG0792@2 NA|NA|NA L Belongs to the UPF0102 family NIBLCNGB_00201 1437610.BREU_2146 1.6e-23 115.2 Bifidobacteriales Bacteria 2GMZX@201174,4D0DN@85004,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives IS30 family NIBLCNGB_00202 326426.Bbr_0806 2.8e-165 587.8 Bifidobacteriales pdxK 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2HS59@201174,4CYQC@85004,COG2240@1,COG2240@2 NA|NA|NA H Phosphomethylpyrimidine kinase NIBLCNGB_00203 326426.Bbr_0807 4.5e-252 876.7 Bifidobacteriales metY 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 Bacteria 2I2EB@201174,4CZCT@85004,COG2873@1,COG2873@2 NA|NA|NA E Aminotransferase class-V NIBLCNGB_00204 326426.Bbr_0808 7.8e-166 589.7 Bifidobacteriales ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJN6@201174,4CZ04@85004,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein NIBLCNGB_00205 326426.Bbr_0809 0.0 1610.5 Bifidobacteriales ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJTZ@201174,4CZUR@85004,COG0577@1,COG0577@2,COG4591@1,COG4591@2 NA|NA|NA MV MacB-like periplasmic core domain NIBLCNGB_00206 326426.Bbr_0810 1.3e-140 505.8 Bifidobacteriales Bacteria 2GJ46@201174,4CYQW@85004,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon NIBLCNGB_00207 326426.Bbr_0811 0.0 1453.7 Bifidobacteriales tcsS2 Bacteria 2GJEG@201174,4CZ1M@85004,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase NIBLCNGB_00208 326426.Bbr_0812 1.6e-293 1014.6 Bifidobacteriales pip 3.4.11.5 ko:K01259 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 2GK03@201174,4CZ9T@85004,COG0596@1,COG0596@2 NA|NA|NA S alpha/beta hydrolase fold NIBLCNGB_00209 326426.Bbr_0813 1.4e-147 528.9 Bifidobacteriales proC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0899,iIT341.HP1158 Bacteria 2GJ7D@201174,4CZIV@85004,COG0345@1,COG0345@2 NA|NA|NA E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline NIBLCNGB_00210 326426.Bbr_0814 9.6e-155 552.7 Bifidobacteriales cjaA ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2GJH8@201174,4CZAC@85004,COG0834@1,COG0834@2 NA|NA|NA ET Bacterial periplasmic substrate-binding proteins NIBLCNGB_00211 326426.Bbr_0815 5.8e-138 496.9 Bifidobacteriales glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 2H1ZM@201174,4CZTK@85004,COG1126@1,COG1126@2 NA|NA|NA E ATP binding protein of ABC transporter for glutamate aspartate K02028 NIBLCNGB_00212 326426.Bbr_0816 1.2e-118 432.6 Bifidobacteriales ko:K02029 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2GN44@201174,4CZG7@85004,COG0765@1,COG0765@2 NA|NA|NA E Binding-protein-dependent transport system inner membrane component NIBLCNGB_00213 326426.Bbr_0817 6.7e-111 406.8 Bifidobacteriales papP ko:K02029 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2GM0I@201174,4CZ8E@85004,COG0765@1,COG0765@2 NA|NA|NA E Binding-protein-dependent transport system inner membrane component NIBLCNGB_00214 326426.Bbr_0818 1.8e-202 711.8 Bifidobacteriales ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 ko:K06942 ko00000,ko03009 Bacteria 2GIXI@201174,4CZBU@85004,COG0012@1,COG0012@2 NA|NA|NA J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner NIBLCNGB_00215 326426.Bbr_0819 1.4e-92 345.5 Actinobacteria ko:K13653 ko00000,ko03000 Bacteria 2GVAR@201174,COG2207@1,COG2207@2,COG3708@1,COG3708@2 NA|NA|NA K Arac family NIBLCNGB_00216 326426.Bbr_0819 1.1e-58 232.6 Actinobacteria ko:K13653 ko00000,ko03000 Bacteria 2GVAR@201174,COG2207@1,COG2207@2,COG3708@1,COG3708@2 NA|NA|NA K Arac family NIBLCNGB_00217 326426.Bbr_0820 2.7e-28 131.0 Bacteria ko:K02890,ko:K07343 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria COG3743@1,COG3743@2 NA|NA|NA S rRNA binding NIBLCNGB_00219 326426.Bbr_0821 1.6e-44 185.3 Bifidobacteriales Bacteria 2GXXK@201174,4D04E@85004,COG0534@1,COG0534@2 NA|NA|NA V MatE NIBLCNGB_00220 326426.Bbr_0821 1.3e-171 609.0 Bifidobacteriales Bacteria 2GXXK@201174,4D04E@85004,COG0534@1,COG0534@2 NA|NA|NA V MatE NIBLCNGB_00221 326426.Bbr_0822 0.0 1495.3 Bifidobacteriales drrC Bacteria 2GJUV@201174,4CYXB@85004,COG0178@1,COG0178@2 NA|NA|NA L ABC transporter NIBLCNGB_00222 216816.GS08_00995 1.6e-14 86.3 Bifidobacteriales 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IEJD@201174,4CZTH@85004,COG3677@1,COG3677@2 NA|NA|NA L Transposase, Mutator family NIBLCNGB_00223 216816.GS08_04195 1.2e-233 815.5 Bifidobacteriales XK27_00240 Bacteria 2HZGJ@201174,4D0D3@85004,COG1510@1,COG1510@2,COG3177@1,COG3177@2 NA|NA|NA K Fic/DOC family NIBLCNGB_00224 216816.GS08_04200 4.1e-60 237.7 Bifidobacteriales yccF Bacteria 2IKS5@201174,4D11K@85004,COG3304@1,COG3304@2 NA|NA|NA S Inner membrane component domain NIBLCNGB_00225 326426.Bbr_0826 1.3e-159 568.9 Bifidobacteriales ksgA 2.1.1.182 ko:K02528 R10716 RC00003,RC03257 ko00000,ko01000,ko03009 Bacteria 2I2II@201174,4CZIK@85004,COG0030@1,COG0030@2 NA|NA|NA J Methyltransferase domain NIBLCNGB_00226 326426.Bbr_0827 2.5e-67 261.9 Bifidobacteriales Bacteria 2IHSV@201174,4D0ZF@85004,COG1917@1,COG1917@2 NA|NA|NA S Cupin 2, conserved barrel domain protein NIBLCNGB_00227 326426.Bbr_0828 1.5e-52 211.8 Bifidobacteriales ko:K07171 ko00000,ko01000,ko02048 Bacteria 2IICB@201174,4D102@85004,COG2337@1,COG2337@2 NA|NA|NA T PemK-like, MazF-like toxin of type II toxin-antitoxin system NIBLCNGB_00228 326426.Bbr_0829 1.1e-37 162.2 Bifidobacteriales ko:K07473 ko00000,ko02048 Bacteria 2IRS1@201174,4D1BV@85004,COG3077@1,COG3077@2 NA|NA|NA L RelB antitoxin NIBLCNGB_00229 326426.Bbr_0830 2.5e-244 850.9 Bifidobacteriales Bacteria 2IEMD@201174,4CZ2C@85004,COG3550@1,COG3550@2 NA|NA|NA S HipA-like C-terminal domain NIBLCNGB_00230 326426.Bbr_0831 2.4e-17 93.6 Bacteria ko:K21498 ko00000,ko02048 Bacteria COG3093@1,COG3093@2 NA|NA|NA K addiction module antidote protein HigA NIBLCNGB_00231 326426.Bbr_0832 1.2e-127 462.6 Bifidobacteriales Bacteria 2HZ9S@201174,4CZ4Z@85004,COG2271@1,COG2271@2 NA|NA|NA G Transmembrane secretion effector NIBLCNGB_00232 216816.GS08_04235 1.1e-119 436.0 Bifidobacteriales Bacteria 2HZJX@201174,4D0QJ@85004,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family NIBLCNGB_00233 547043.BIFPSEUDO_04438 2.2e-11 73.6 Bifidobacteriales Bacteria 29G83@1,2GQWW@201174,3035W@2,4D1G9@85004 NA|NA|NA NIBLCNGB_00234 566552.BIFCAT_01925 0.0 1242.6 Bifidobacteriales cysB 4.2.1.22 ko:K01697,ko:K18926 ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230 M00035,M00338,M00715 R00891,R01290,R04942 RC00056,RC00069,RC00256,RC00489,RC01246 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.1.3.30 Bacteria 2GIZX@201174,4CZWX@85004,COG0477@1,COG0517@1,COG0517@2,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily NIBLCNGB_00235 216816.GS08_04250 1.2e-13 81.3 Bifidobacteriales ko:K08217 br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 Bacteria 2GK06@201174,4D2W9@85004,COG0477@1,COG0477@2 NA|NA|NA EGP Transmembrane secretion effector NIBLCNGB_00236 566552.BIFCAT_00064 2e-286 991.1 Bifidobacteriales glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 R02111 ko00000,ko00001,ko01000 GT35 Bacteria 2GIVZ@201174,4CZ3V@85004,COG0058@1,COG0058@2 NA|NA|NA G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties NIBLCNGB_00237 326426.Bbr_0846 8.1e-243 845.9 Bifidobacteriales nagA 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 R02059 RC00166,RC00300 ko00000,ko00001,ko01000 Bacteria 2GK1E@201174,4CZKB@85004,COG1820@1,COG1820@2 NA|NA|NA G Amidohydrolase family NIBLCNGB_00238 326426.Bbr_0847 1.9e-147 528.5 Bifidobacteriales nagB 3.1.1.31,3.5.99.6 ko:K01057,ko:K02564 ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R00765,R02035 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK7F@201174,4CYYE@85004,COG0363@1,COG0363@2 NA|NA|NA G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion NIBLCNGB_00239 326426.Bbr_0848 2.8e-174 617.8 Bifidobacteriales 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GZ27@201174,4CZII@85004,COG1940@1,COG1940@2 NA|NA|NA GK ROK family NIBLCNGB_00240 326426.Bbr_0849 3.1e-220 770.8 Bifidobacteriales Bacteria 2GKMZ@201174,4CZUF@85004,COG1940@1,COG1940@2 NA|NA|NA GK ROK family NIBLCNGB_00241 326426.Bbr_0850 6.4e-159 566.6 Bifidobacteriales yeaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 4.2.1.9,5.1.3.15 ko:K01687,ko:K01792 ko00010,ko00290,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00010,map00290,map00770,map01100,map01110,map01120,map01130,map01210,map01230 M00019,M00570 R01209,R02739,R04441,R05070 RC00468,RC00563,RC01714 ko00000,ko00001,ko00002,ko01000 Bacteria 2IIUH@201174,4CZWN@85004,COG0676@1,COG0676@2 NA|NA|NA G Aldose 1-epimerase NIBLCNGB_00242 326426.Bbr_0851 7.5e-253 879.4 Bifidobacteriales gtr GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 2.A.1.1 Bacteria 2HC9X@201174,4D2XP@85004,COG0477@1,COG0477@2 NA|NA|NA U Sugar (and other) transporter NIBLCNGB_00243 326426.Bbr_0852 0.0 1078.9 Bifidobacteriales Bacteria 2GJ8H@201174,4D246@85004,COG3119@1,COG3119@2 NA|NA|NA P Domain of unknown function (DUF4976) NIBLCNGB_00244 326426.Bbr_0853 4e-272 943.3 Bifidobacteriales aslB GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:1901564 ko:K06871 ko00000 Bacteria 2HZTM@201174,4D1Q0@85004,COG0641@1,COG0641@2 NA|NA|NA C Iron-sulfur cluster-binding domain NIBLCNGB_00245 326426.Bbr_0854 1.6e-106 392.5 Bifidobacteriales ko:K07090 ko00000 Bacteria 2I5VT@201174,4D23D@85004,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE NIBLCNGB_00246 326426.Bbr_0855 1.1e-59 235.7 Bifidobacteriales Bacteria 2IF4K@201174,4D0JP@85004,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain NIBLCNGB_00247 566552.BIFCAT_01933 3.7e-92 344.4 Bifidobacteriales ko:K07090 ko00000 Bacteria 2GJCC@201174,4CZ65@85004,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE NIBLCNGB_00248 326426.Bbr_0857 1.3e-60 238.8 Bifidobacteriales MA20_22310 4.4.1.5 ko:K01759 ko00620,map00620 R02530 RC00004,RC00740 ko00000,ko00001,ko01000 Bacteria 2II51@201174,4D0V7@85004,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NIBLCNGB_00249 326426.Bbr_0859 1.1e-229 802.4 Bifidobacteriales ko:K08217 br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 Bacteria 2I2EY@201174,4D02G@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily NIBLCNGB_00250 326426.Bbr_0860 1.6e-108 398.7 Bifidobacteriales 3.1.3.27 ko:K18697 ko00564,map00564 R02029 RC00017 ko00000,ko00001,ko01000 Bacteria 2GMVR@201174,4D0CF@85004,COG0560@1,COG0560@2 NA|NA|NA E haloacid dehalogenase-like hydrolase NIBLCNGB_00251 326426.Bbr_0861 1.4e-161 575.5 Bifidobacteriales 3.1.3.73 ko:K02226,ko:K07814 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000,ko02022 Bacteria 2GN7B@201174,4CZFM@85004,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family NIBLCNGB_00252 326426.Bbr_0862 8.4e-235 819.3 Bifidobacteriales rutG GO:0003674,GO:0005215,GO:0005350,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0006810,GO:0006855,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0015205,GO:0015210,GO:0015238,GO:0015851,GO:0015855,GO:0015857,GO:0015893,GO:0016020,GO:0016021,GO:0017144,GO:0019860,GO:0022857,GO:0031224,GO:0031226,GO:0034641,GO:0042221,GO:0042493,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072527,GO:0072529,GO:0072531,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1903791,GO:1904082 ko:K02824,ko:K03458,ko:K09016 ko00000,ko02000 2.A.40,2.A.40.1.1,2.A.40.1.2,2.A.40.1.3 iECO103_1326.ECO103_1052,iECUMN_1333.ECUMN_1189 Bacteria 2GMH6@201174,4CZR8@85004,COG2233@1,COG2233@2 NA|NA|NA F Permease family NIBLCNGB_00253 326426.Bbr_0863 0.0 1107.4 Bifidobacteriales deaD 3.6.4.13 ko:K05592,ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2GIUR@201174,4CZ4K@85004,COG0513@1,COG0513@2 NA|NA|NA JKL helicase superfamily c-terminal domain NIBLCNGB_00254 326426.Bbr_0864 1.2e-257 895.2 Bifidobacteriales nplT Bacteria 2GJUT@201174,4D075@85004,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain NIBLCNGB_00255 326426.Bbr_0865 9.8e-189 666.0 Bifidobacteriales pit ko:K03306 ko00000 2.A.20 Bacteria 2GJHK@201174,4CZM7@85004,COG0306@1,COG0306@2 NA|NA|NA P Phosphate transporter family NIBLCNGB_00256 326426.Bbr_0866 3.3e-112 411.0 Bifidobacteriales MA20_27875 ko:K02039,ko:K07220 ko00000 Bacteria 2HNQ5@201174,4CZVQ@85004,COG1392@1,COG1392@2 NA|NA|NA P Protein of unknown function DUF47 NIBLCNGB_00257 326426.Bbr_0867 8.3e-114 416.4 Bifidobacteriales Bacteria 2IBZ9@201174,4D07J@85004,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon NIBLCNGB_00258 326426.Bbr_0868 5.7e-242 843.2 Bifidobacteriales Bacteria 2I9G4@201174,4CZHY@85004,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase NIBLCNGB_00259 158787.BSCA_2234 2.5e-119 435.3 Bifidobacteriales pacL 3.6.3.8,3.6.3.9 ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 ko00000,ko00001,ko01000,ko04147 3.A.3.1,3.A.3.2 Bacteria 2GJJC@201174,4D20B@85004,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus NIBLCNGB_00260 326426.Bbr_0870 1.1e-186 659.1 Bifidobacteriales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GIY8@201174,4CYUQ@85004,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities NIBLCNGB_00261 326426.Bbr_0871 7.5e-225 786.2 Bifidobacteriales ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IBJP@201174,4CZD5@85004,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 family transporter protein NIBLCNGB_00262 326426.Bbr_0872 5.6e-248 863.2 Bifidobacteriales ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2H9HW@201174,4CZ1J@85004,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 family transporter protein NIBLCNGB_00263 326426.Bbr_0873 3.5e-285 986.9 Bifidobacteriales 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GZ30@201174,4CYSX@85004,COG2865@1,COG2865@2 NA|NA|NA K Putative ATP-dependent DNA helicase recG C-terminal NIBLCNGB_00264 326426.Bbr_0874 1.5e-39 168.3 Bifidobacteriales Bacteria 2IPPH@201174,4D0X0@85004,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase family NIBLCNGB_00265 326426.Bbr_0875 1.9e-196 691.8 Bifidobacteriales Bacteria 2CGVZ@1,2IEU5@201174,33209@2,4CZAJ@85004 NA|NA|NA NIBLCNGB_00266 326426.Bbr_0876 4.8e-111 407.1 Bifidobacteriales 3.4.13.21 ko:K05995 ko00000,ko01000,ko01002 Bacteria 2GN35@201174,4D10R@85004,COG3340@1,COG3340@2 NA|NA|NA E Peptidase family S51 NIBLCNGB_00267 326426.Bbr_0877 1.8e-110 405.2 Bifidobacteriales pncA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 ko:K08281,ko:K12132 ko00760,ko01100,map00760,map01100 R01268 RC00100 ko00000,ko00001,ko01000,ko01001 iE2348C_1286.E2348C_1895,iECs_1301.ECs2475,iZ_1308.Z2802 Bacteria 2IFQW@201174,4CYTT@85004,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family NIBLCNGB_00268 326426.Bbr_0878 2.6e-161 574.7 Bifidobacteriales Bacteria 2I38D@201174,4D2XJ@85004,COG0791@1,COG0791@2 NA|NA|NA M pfam nlp p60 NIBLCNGB_00269 326426.Bbr_0879 7.4e-160 569.7 Bifidobacteriales Bacteria 2GNRY@201174,4D02B@85004,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 NIBLCNGB_00270 326426.Bbr_0880 1.1e-40 172.2 Bifidobacteriales Bacteria 2B2KB@1,2GV1B@201174,31V5N@2,4D1EE@85004 NA|NA|NA S Protein of unknown function (DUF2975) NIBLCNGB_00271 216816.GS08_04420 2.8e-31 140.6 Bifidobacteriales yozG ko:K07727 ko00000,ko03000 Bacteria 2GQZM@201174,4D1EQ@85004,COG3655@1,COG3655@2 NA|NA|NA K Cro/C1-type HTH DNA-binding domain NIBLCNGB_00272 326426.Bbr_0882 2e-242 844.7 Bifidobacteriales pbuX ko:K03458 ko00000 2.A.40 Bacteria 2GMH6@201174,4CZ9F@85004,COG2233@1,COG2233@2 NA|NA|NA F Permease family NIBLCNGB_00273 326426.Bbr_0883 9.7e-106 389.4 Bifidobacteriales xpt 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko04147 Bacteria 2GJ3S@201174,4CYSZ@85004,COG0503@1,COG0503@2 NA|NA|NA F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis NIBLCNGB_00274 326426.Bbr_0884 0.0 1540.0 Bifidobacteriales pcrA GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GISS@201174,4CYRJ@85004,COG0210@1,COG0210@2 NA|NA|NA L DNA helicase NIBLCNGB_00275 326426.Bbr_0885 1.1e-60 239.2 Bifidobacteriales Bacteria 2CBVU@1,2IKKE@201174,3324G@2,4D106@85004 NA|NA|NA S Domain of unknown function (DUF4418) NIBLCNGB_00276 326426.Bbr_0886 2.2e-216 758.1 Bifidobacteriales ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2H8C2@201174,4CZB5@85004,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family NIBLCNGB_00277 326426.Bbr_0887 3.9e-162 577.4 Bifidobacteriales lolD ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IATV@201174,4CZMH@85004,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter NIBLCNGB_00278 326426.Bbr_0888 1.7e-108 398.7 Bifidobacteriales rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 ko:K02986 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GIRX@201174,4CYSP@85004,COG0522@1,COG0522@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit NIBLCNGB_00279 326426.Bbr_0889 4.9e-153 547.0 Bifidobacteriales ko:K07010 ko00000,ko01002 Bacteria 2GIV6@201174,4D043@85004,COG2071@1,COG2071@2 NA|NA|NA S Peptidase C26 NIBLCNGB_00280 326426.Bbr_0890 2.5e-91 341.3 Bifidobacteriales 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 Bacteria 2IMXP@201174,4D1XM@85004,COG0295@1,COG0295@2 NA|NA|NA F cytidine deaminase activity NIBLCNGB_00281 326426.Bbr_0891 1.8e-46 191.8 Bifidobacteriales sdpI Bacteria 2GWJG@201174,4D1RC@85004,COG5658@1,COG5658@2 NA|NA|NA S SdpI/YhfL protein family NIBLCNGB_00282 216816.GS08_04475 7.9e-111 406.4 Bifidobacteriales Bacteria 2GM42@201174,4D0N1@85004,COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase-like superfamily NIBLCNGB_00283 326426.Bbr_0893 3.5e-66 257.3 Bifidobacteriales Bacteria 2GZTW@201174,4D25G@85004,COG2337@1,COG2337@2 NA|NA|NA T PemK-like, MazF-like toxin of type II toxin-antitoxin system NIBLCNGB_00284 326426.Bbr_0894 2.3e-47 194.5 Bifidobacteriales relB ko:K07473 ko00000,ko02048 Bacteria 2GRAY@201174,4D1J9@85004,COG3077@1,COG3077@2 NA|NA|NA L RelB antitoxin NIBLCNGB_00285 216816.GS08_07340 3.3e-17 93.6 Bifidobacteriales Bacteria 2H4CW@201174,4D25Y@85004,COG2826@1,COG2826@2 NA|NA|NA L Helix-turn-helix domain NIBLCNGB_00286 398513.BBNG_00001 1.1e-54 219.5 Bifidobacteriales Bacteria 2GMZX@201174,4D1MQ@85004,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives IS30 family NIBLCNGB_00289 1437610.BREU_2185 8.8e-297 1025.8 Bifidobacteriales ko:K06889 ko00000 Bacteria 2IA0Y@201174,4D06W@85004,COG1073@1,COG1073@2 NA|NA|NA S alpha beta NIBLCNGB_00290 1437610.BREU_2188 1.8e-136 492.3 Bifidobacteriales Bacteria 2GMIM@201174,4D05F@85004,COG2390@1,COG2390@2 NA|NA|NA K Putative sugar-binding domain NIBLCNGB_00291 1437610.BREU_2362 2.1e-110 406.0 Bifidobacteriales Bacteria 2GVNB@201174,4CZGZ@85004,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily NIBLCNGB_00292 1437610.BREU_2349 1.9e-87 329.3 Bifidobacteriales Bacteria 2HGIX@201174,4CZUK@85004,COG0657@1,COG0657@2 NA|NA|NA I Hydrolase, alpha beta domain protein NIBLCNGB_00293 518635.BIFANG_03163 2.3e-219 768.1 Bifidobacteriales 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 R09660 RC00477 ko00000,ko00001,ko01000 Bacteria 2GM63@201174,4D06J@85004,COG0402@1,COG0402@2 NA|NA|NA F Amidohydrolase family NIBLCNGB_00294 518635.BIFANG_03164 2.2e-101 375.2 Bifidobacteriales ko:K03458 ko00000 2.A.40 Bacteria 2GMH6@201174,4D2TM@85004,COG2233@1,COG2233@2 NA|NA|NA F Permease family NIBLCNGB_00295 398513.BBNG_00722 1.6e-46 191.8 Bifidobacteriales ko:K07483 ko00000 Bacteria 2IQ8F@201174,4D1BJ@85004,COG2963@1,COG2963@2 NA|NA|NA L Transposase NIBLCNGB_00296 398513.BBNG_00723 1.8e-97 362.1 Bifidobacteriales tnp7109-21 Bacteria 2GKDY@201174,4CZUB@85004,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain NIBLCNGB_00297 216816.GS08_09870 2e-202 711.4 Bifidobacteriales Bacteria 2I9JH@201174,4D2KU@85004,COG4974@1,COG4974@2 NA|NA|NA L Phage integrase, N-terminal SAM-like domain NIBLCNGB_00298 216816.GS08_03825 5.9e-193 679.9 Bifidobacteriales Bacteria 2I9B8@201174,4D2Q1@85004,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase family NIBLCNGB_00299 216816.GS08_02215 4.2e-228 797.0 Actinobacteria xerC_1 ko:K04763 ko00000,ko03036 Bacteria 2HB7R@201174,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family NIBLCNGB_00300 216816.GS08_09885 2.8e-88 331.3 Bifidobacteriales Bacteria 2GKW1@201174,4CYXY@85004,COG2801@1,COG2801@2,COG2963@1,COG2963@2 NA|NA|NA L HTH-like domain NIBLCNGB_00301 216816.GS08_09885 3.3e-66 257.7 Bifidobacteriales Bacteria 2GKW1@201174,4CYXY@85004,COG2801@1,COG2801@2,COG2963@1,COG2963@2 NA|NA|NA L HTH-like domain NIBLCNGB_00302 398513.BBNG_01485 5.5e-63 247.3 Bifidobacteriales Bacteria 2GMZX@201174,4D0DN@85004,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives IS30 family NIBLCNGB_00303 1437608.BBIA_0795 1.6e-41 176.0 Bifidobacteriales tnp3514b GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K07497 ko00000 Bacteria 2HRER@201174,4D28U@85004,COG2801@1,COG2801@2,COG3415@1,COG3415@2 NA|NA|NA L Winged helix-turn helix NIBLCNGB_00304 326426.Bbr_0024 8.8e-17 92.4 Bifidobacteriales Bacteria 2GMZX@201174,4D0DN@85004,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives IS30 family NIBLCNGB_00305 326426.Bbr_0895 3.4e-126 457.6 Bifidobacteriales pgm3 Bacteria 2GK2I@201174,4CZH2@85004,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family NIBLCNGB_00306 216816.GS08_04500 2.3e-55 221.5 Bifidobacteriales WQ51_05790 Bacteria 2II1J@201174,4D0VH@85004,COG4768@1,COG4768@2 NA|NA|NA S Bacterial protein of unknown function (DUF948) NIBLCNGB_00307 326426.Bbr_0897 1.6e-35 154.8 Bifidobacteriales Bacteria 2B9VR@1,2IQYT@201174,3238X@2,4D16I@85004 NA|NA|NA NIBLCNGB_00308 326426.Bbr_0898 0.0 1729.1 Bifidobacteriales alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GIUG@201174,4CZQN@85004,COG0013@1,COG0013@2 NA|NA|NA J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain NIBLCNGB_00309 326426.Bbr_0899 2.7e-71 274.6 Bifidobacteriales yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07447 ko00000,ko01000 Bacteria 2IQB0@201174,4D0WQ@85004,COG0816@1,COG0816@2 NA|NA|NA L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA NIBLCNGB_00310 326426.Bbr_0900 2.3e-194 684.9 Bifidobacteriales mltG ko:K07082 ko00000 Bacteria 2GKGQ@201174,4CZID@85004,COG1559@1,COG1559@2 NA|NA|NA S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation NIBLCNGB_00311 216816.GS08_04525 1e-68 266.2 Bifidobacteriales 3.4.23.43 ko:K02654 M00331 ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 Bacteria 2B59B@1,2GRM1@201174,31Y3G@2,4D110@85004 NA|NA|NA S Type IV leader peptidase family NIBLCNGB_00312 326426.Bbr_0902 2.5e-217 761.1 Bifidobacteriales aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0976,iNJ661.Rv2540c Bacteria 2GJJN@201174,4CZ43@85004,COG0082@1,COG0082@2 NA|NA|NA E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system NIBLCNGB_00313 326426.Bbr_0903 0.0 1087.8 Bifidobacteriales aroK GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003856,GO:0004765,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016835,GO:0016838,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71,4.2.3.4 ko:K00891,ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIUZ@201174,4CZ2G@85004,COG0337@1,COG0337@2,COG0703@1,COG0703@2 NA|NA|NA H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) NIBLCNGB_00314 326426.Bbr_0904 1.3e-78 298.9 Bifidobacteriales aroQ GO:0003674,GO:0003824,GO:0003855,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 iIT341.HP1038 Bacteria 2IMBY@201174,4D0Q6@85004,COG0757@1,COG0757@2 NA|NA|NA E Catalyzes a trans-dehydration via an enolate intermediate NIBLCNGB_00315 326426.Bbr_0905 0.0 1121.7 Bifidobacteriales pyrG GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iHN637.CLJU_RS01075,iNJ661.Rv1699,iPC815.YPO3377 Bacteria 2GJ13@201174,4CYWE@85004,COG0504@1,COG0504@2 NA|NA|NA F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates NIBLCNGB_00316 326426.Bbr_0906 0.0 1077.4 Bifidobacteriales Bacteria 2GQ7D@201174,4CZ5A@85004,COG1376@1,COG1376@2 NA|NA|NA S L,D-transpeptidase catalytic domain NIBLCNGB_00317 326426.Bbr_0907 1.5e-291 1008.1 Bifidobacteriales sufB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 ko:K07033,ko:K09014 ko00000 Bacteria 2GKCZ@201174,4CZPQ@85004,COG0719@1,COG0719@2 NA|NA|NA O FeS assembly protein SufB NIBLCNGB_00318 326426.Bbr_0908 1.6e-235 821.6 Bifidobacteriales sufD GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136 ko:K09015 ko00000 iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144 Bacteria 2GJNV@201174,4CZEE@85004,COG0719@1,COG0719@2 NA|NA|NA O FeS assembly protein SufD NIBLCNGB_00319 326426.Bbr_0909 7e-144 516.5 Bifidobacteriales sufC ko:K09013 ko00000,ko02000 Bacteria 2GKB7@201174,4CZU1@85004,COG0396@1,COG0396@2 NA|NA|NA O FeS assembly ATPase SufC NIBLCNGB_00320 326426.Bbr_0910 9.4e-239 832.4 Bifidobacteriales sufS GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 Bacteria 2GIVK@201174,4CZIU@85004,COG0520@1,COG0520@2 NA|NA|NA E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine NIBLCNGB_00321 326426.Bbr_0911 4e-101 374.0 Bifidobacteriales iscU ko:K04488 ko00000 Bacteria 2IHY9@201174,4CZU5@85004,COG0822@1,COG0822@2 NA|NA|NA C SUF system FeS assembly protein, NifU family NIBLCNGB_00322 326426.Bbr_0912 3.2e-109 401.0 Bifidobacteriales yitW ko:K02612,ko:K03593 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001,ko03029,ko03036 Bacteria 2IKUH@201174,4CYRH@85004,COG2151@1,COG2151@2 NA|NA|NA S Iron-sulfur cluster assembly protein NIBLCNGB_00323 326426.Bbr_0913 4.4e-241 840.1 Bifidobacteriales glgC GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2768 Bacteria 2I2EF@201174,4CZ4E@85004,COG0448@1,COG0448@2 NA|NA|NA H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans NIBLCNGB_00324 326426.Bbr_0914 3.3e-166 590.9 Bifidobacteriales spoU 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 2GJ12@201174,4CYQ6@85004,COG0566@1,COG0566@2 NA|NA|NA J SpoU rRNA Methylase family NIBLCNGB_00326 326426.Bbr_0915 6.8e-148 530.0 Bifidobacteriales rsmE 2.1.1.193 ko:K09761 ko00000,ko01000,ko03009 Bacteria 2GTKX@201174,4CZAD@85004,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit NIBLCNGB_00327 326426.Bbr_0916 4.4e-58 230.3 Bifidobacteriales hinT GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019478,GO:0019752,GO:0043436,GO:0043530,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046144,GO:0046395,GO:0046416,GO:0046436,GO:0055130,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.1.226,2.1.1.227 ko:K02503,ko:K06442 ko00000,ko01000,ko03009,ko04147 Bacteria 2IHPT@201174,4D130@85004,COG0537@1,COG0537@2 NA|NA|NA FG Scavenger mRNA decapping enzyme C-term binding NIBLCNGB_00328 326426.Bbr_0917 2.5e-217 761.1 Bifidobacteriales phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06217 ko00000 Bacteria 2GK0W@201174,4CZJH@85004,COG1702@1,COG1702@2 NA|NA|NA T PhoH-like protein NIBLCNGB_00329 326426.Bbr_0918 4.7e-102 377.1 Bifidobacteriales ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 2GMUF@201174,4CZJF@85004,COG0319@1,COG0319@2 NA|NA|NA S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA NIBLCNGB_00330 326426.Bbr_0919 5.1e-249 866.7 Bifidobacteriales corC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2GIWR@201174,4CZ1W@85004,COG1253@1,COG1253@2 NA|NA|NA S CBS domain NIBLCNGB_00331 326426.Bbr_0920 3.1e-184 651.0 Bifidobacteriales era GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043021,GO:0043024,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070181,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:1901363 ko:K03595 ko00000,ko03009,ko03029 Bacteria 2GJJE@201174,4CYZH@85004,COG1159@1,COG1159@2 NA|NA|NA S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism NIBLCNGB_00332 326426.Bbr_0921 0.0 1340.5 Bifidobacteriales fadD 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2GIXQ@201174,4CYYJ@85004,COG1022@1,COG1022@2 NA|NA|NA I AMP-binding enzyme NIBLCNGB_00333 326426.Bbr_0922 9.7e-198 696.0 Bifidobacteriales pntA 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 2I2FZ@201174,4CZZ3@85004,COG3288@1,COG3288@2 NA|NA|NA C NAD(P) transhydrogenase subunit alpha part 1 K00324 NIBLCNGB_00334 326426.Bbr_0923 2.1e-43 181.4 Bifidobacteriales pntAA 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 2IKR9@201174,4D12D@85004,COG3288@1,COG3288@2 NA|NA|NA C 4TM region of pyridine nucleotide transhydrogenase, mitoch NIBLCNGB_00335 326426.Bbr_0924 1.5e-232 812.0 Bifidobacteriales pntB 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 2GNKB@201174,4CZF5@85004,COG1282@1,COG1282@2 NA|NA|NA C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane NIBLCNGB_00336 326426.Bbr_0925 1.4e-234 818.5 Bifidobacteriales yhjX ko:K08177 ko00000,ko02000 2.A.1.11 Bacteria 2I2ID@201174,4CZX9@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily NIBLCNGB_00337 326426.Bbr_0926 6.9e-102 376.7 Bifidobacteriales ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02897 ko03010,map03010 M00178 ko00000,ko00001,ko00002,ko03011 Bacteria 2GJPJ@201174,4CZ7W@85004,COG1825@1,COG1825@2 NA|NA|NA J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance NIBLCNGB_00338 326426.Bbr_0927 1.6e-226 791.6 Bifidobacteriales ilvE GO:0000082,GO:0000278,GO:0003674,GO:0003824,GO:0004084,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006573,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008283,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009082,GO:0009083,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0022402,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044770,GO:0044772,GO:0044843,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607,GO:1903047 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GKJ1@201174,4CZD9@85004,COG0115@1,COG0115@2 NA|NA|NA E Amino-transferase class IV NIBLCNGB_00339 326426.Bbr_0928 2.9e-146 524.6 Bifidobacteriales mazG GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0022607,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0042454,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0047693,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 ko:K02428 ko00230,map00230 R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 Bacteria 2GNKC@201174,4CZ9U@85004,COG1694@1,COG3956@2 NA|NA|NA S Psort location Cytoplasmic, score 8.87 NIBLCNGB_00340 326426.Bbr_0929 3.3e-138 497.7 Bifidobacteriales GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2GMI4@201174,4CZ51@85004,COG2860@1,COG2860@2 NA|NA|NA S UPF0126 domain NIBLCNGB_00341 326426.Bbr_0930 5.8e-34 149.8 Bifidobacteriales rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02968 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ73@201174,4D18U@85004,COG0268@1,COG0268@2 NA|NA|NA J Binds directly to 16S ribosomal RNA NIBLCNGB_00342 326426.Bbr_0931 0.0 1242.3 Bifidobacteriales lepA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03596 ko05134,map05134 ko00000,ko00001 Bacteria 2GJAB@201174,4CYWI@85004,COG0481@1,COG0481@2 NA|NA|NA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner NIBLCNGB_00343 326426.Bbr_0932 9.7e-255 885.6 Bifidobacteriales hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 iNJ661.Rv2388c Bacteria 2GJXX@201174,4CZ81@85004,COG0635@1,COG0635@2 NA|NA|NA H Involved in the biosynthesis of porphyrin-containing compound NIBLCNGB_00345 326426.Bbr_0934 2.2e-190 671.4 Bifidobacteriales ko:K02529 ko00000,ko03000 Bacteria 2GK1X@201174,4CZS8@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor NIBLCNGB_00346 326426.Bbr_0936 0.0 3048.8 Bifidobacteriales gltB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 Bacteria 2GN09@201174,4CZB8@85004,COG0067@1,COG0067@2,COG0069@1,COG0069@2,COG0070@1,COG0070@2 NA|NA|NA E glutamate synthase NADPH large subunit NIBLCNGB_00347 326426.Bbr_0937 5.4e-305 1052.7 Bifidobacteriales gltD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450 Bacteria 2GJ0A@201174,4CZ7B@85004,COG0493@1,COG0493@2 NA|NA|NA C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NIBLCNGB_00349 326426.Bbr_0938 5.4e-44 183.3 Bifidobacteriales Bacteria 2A95S@1,2HBBF@201174,30YAB@2,4D2NR@85004 NA|NA|NA NIBLCNGB_00350 326426.Bbr_0939 0.0 1100.5 Bifidobacteriales ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2GIUH@201174,4CZFK@85004,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substrate-binding protein, family 5 NIBLCNGB_00351 216816.GS08_04760 0.0 1337.0 Bifidobacteriales Bacteria 28J61@1,2HZIR@201174,2Z91S@2,4D0KC@85004 NA|NA|NA S Glycosyl hydrolases related to GH101 family, GH129 NIBLCNGB_00352 216816.GS08_04765 1e-81 309.3 Bifidobacteriales Bacteria 2BI32@1,2IDD6@201174,32C84@2,4D0PC@85004 NA|NA|NA NIBLCNGB_00353 326426.Bbr_0942 1.3e-243 848.6 Bifidobacteriales glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 ko:K16148 ko00500,ko01100,map00500,map01100 R02421,R11530 RC00005,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 GT4 Bacteria 2I2EE@201174,4CZKY@85004,COG0297@1,COG0297@2 NA|NA|NA G Starch synthase catalytic domain NIBLCNGB_00354 326426.Bbr_0943 4.2e-158 563.9 Bifidobacteriales modF GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21,3.6.3.34 ko:K02013,ko:K02028,ko:K05776 ko02010,map02010 M00189,M00236,M00240 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14,3.A.1.3 Bacteria 2GIXX@201174,4CZDS@85004,COG1119@1,COG1119@2 NA|NA|NA P ATPases associated with a variety of cellular activities NIBLCNGB_00355 326426.Bbr_0944 2.4e-158 564.7 Bifidobacteriales Bacteria 2GNWG@201174,4CZY9@85004,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase NIBLCNGB_00356 500632.CLONEX_01141 8.2e-09 66.2 Firmicutes Bacteria 1VWQI@1239,2F873@1,340KD@2 NA|NA|NA S Psort location Cytoplasmic, score 8.87 NIBLCNGB_00357 622312.ROSEINA2194_01078 4.7e-79 300.4 Clostridia ko:K03088 ko00000,ko03021 Bacteria 1UVHM@1239,24DWE@186801,COG1595@1,COG1595@2 NA|NA|NA K Psort location Cytoplasmic, score NIBLCNGB_00360 326426.Bbr_0947 3.4e-106 391.0 Bifidobacteriales bcp GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0032843,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K03564 ko00000,ko01000 iPC815.YPO3064 Bacteria 2IHZ6@201174,4D0PN@85004,COG1225@1,COG1225@2 NA|NA|NA O Redoxin NIBLCNGB_00361 326426.Bbr_0948 3.8e-134 484.2 Bifidobacteriales Bacteria 2ARR4@1,2IG5G@201174,31H25@2,4D0U6@85004 NA|NA|NA NIBLCNGB_00365 326426.Bbr_0954 7.8e-137 493.0 Actinobacteria yfbU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 ko:K09161 ko00000 Bacteria 2ID7G@201174,COG3013@1,COG3013@2 NA|NA|NA S YfbU domain NIBLCNGB_00368 1437603.BMON_0329 2.2e-30 141.0 Bifidobacteriales Bacteria 2GJ39@201174,4CZC0@85004,COG4279@1,COG4279@2 NA|NA|NA S zinc finger NIBLCNGB_00369 1437610.BREU_2146 1.7e-39 169.5 Bifidobacteriales Bacteria 2GMZX@201174,4D0DN@85004,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives IS30 family NIBLCNGB_00370 1437610.BREU_2146 2.7e-09 66.6 Bifidobacteriales Bacteria 2GMZX@201174,4D0DN@85004,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives IS30 family NIBLCNGB_00371 1122216.AUHW01000005_gene498 2.1e-19 102.8 Negativicutes Bacteria 1V775@1239,28KYP@1,2ZAE6@2,4H7DY@909932 NA|NA|NA S Domain of unknown function DUF1828 NIBLCNGB_00372 158787.BSCA_1450 1.5e-33 149.1 Bifidobacteriales rarD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 ko:K05786 ko00000,ko02000 2.A.7.7 Bacteria 2GKCP@201174,4D0PS@85004,COG2962@1,COG2962@2 NA|NA|NA S EamA-like transporter family NIBLCNGB_00373 326426.Bbr_0958 9.2e-126 456.1 Bifidobacteriales ko:K07039,ko:K09858 ko00000 Bacteria 2I5YJ@201174,4D17C@85004,COG3012@1,COG3012@2 NA|NA|NA S Plasmid pRiA4b ORF-3-like protein NIBLCNGB_00374 326426.Bbr_0959 2.5e-129 468.0 Bifidobacteriales Bacteria 2EINA@1,2ICYX@201174,33CDM@2,4CZUT@85004 NA|NA|NA NIBLCNGB_00376 326426.Bbr_0961 4e-178 630.6 Bifidobacteriales Bacteria 2GNKU@201174,4CZVA@85004,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold NIBLCNGB_00377 326426.Bbr_0962 9.1e-92 342.8 Bifidobacteriales Bacteria 2IFEC@201174,4D01A@85004,COG2110@1,COG2110@2 NA|NA|NA S Appr-1'-p processing enzyme NIBLCNGB_00378 326426.Bbr_0963 1.9e-146 525.0 Bifidobacteriales Bacteria 2IRS9@201174,4D018@85004,COG4186@1,COG4186@2 NA|NA|NA S phosphoesterase or phosphohydrolase NIBLCNGB_00379 326426.Bbr_0964 2.6e-140 504.6 Bifidobacteriales tenA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 Bacteria 2IA0S@201174,4CZUI@85004,COG0819@1,COG0819@2 NA|NA|NA K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway NIBLCNGB_00381 326426.Bbr_0966 5.1e-133 480.3 Bifidobacteriales ko:K06999 ko00000 Bacteria 2GNIF@201174,4D0TH@85004,COG0400@1,COG0400@2 NA|NA|NA S Phospholipase/Carboxylesterase NIBLCNGB_00382 326426.Bbr_0967 7.8e-202 709.5 Bifidobacteriales trmI GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 ko:K07442 ko00000,ko01000,ko03016 Bacteria 2GJPD@201174,4CYUG@85004,COG2519@1,COG2519@2 NA|NA|NA J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA NIBLCNGB_00383 326426.Bbr_0968 1.3e-99 369.0 Bifidobacteriales sixA 3.6.1.55 ko:K03574,ko:K08296 ko00000,ko01000,ko03400 Bacteria 2GJ0I@201174,4D05N@85004,COG2062@1,COG2062@2 NA|NA|NA T Phosphoglycerate mutase family NIBLCNGB_00385 326426.Bbr_0969 0.0 1511.1 Bifidobacteriales metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131 Bacteria 2GIXA@201174,4CYWM@85004,COG0620@1,COG0620@2 NA|NA|NA E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation NIBLCNGB_00386 326426.Bbr_0970 5.7e-163 580.1 Bifidobacteriales metF GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 ko:K00297,ko:K21010 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,ko02025,map00670,map00720,map01100,map01120,map01200,map01523,map02025 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 iPC815.YPO0117,iSBO_1134.SBO_3961 Bacteria 2GJTN@201174,4CZ22@85004,COG0685@1,COG0685@2 NA|NA|NA E Methylenetetrahydrofolate reductase NIBLCNGB_00387 326426.Bbr_0971 1.7e-187 661.8 Bifidobacteriales cbh 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 2GK9Z@201174,4CZNU@85004,COG3049@1,COG3049@2 NA|NA|NA M Linear amide C-N hydrolase, choloylglycine hydrolase family protein NIBLCNGB_00388 326426.Bbr_0972 0.0 2090.8 Bifidobacteriales glnE GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 ko:K00982 ko00000,ko01000 Bacteria 2GJ91@201174,4CYQE@85004,COG1391@1,COG1391@2 NA|NA|NA H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell NIBLCNGB_00389 326426.Bbr_0973 9.2e-178 629.4 Bifidobacteriales pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 iZ_1308.Z5856 Bacteria 2GKNA@201174,4CYZR@85004,COG0540@1,COG0540@2 NA|NA|NA F Belongs to the ATCase OTCase family NIBLCNGB_00390 326426.Bbr_0974 7e-74 283.1 Bifidobacteriales pyrI GO:0003674,GO:0003824,GO:0004070,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00608,ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 Bacteria 2IFDF@201174,4D0QN@85004,COG1781@1,COG1781@2 NA|NA|NA F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein NIBLCNGB_00391 326426.Bbr_0975 2.4e-289 1000.7 Bifidobacteriales pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ0T@201174,4CZIW@85004,COG0044@1,COG0044@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily NIBLCNGB_00392 326426.Bbr_0976 1.5e-175 622.1 Bifidobacteriales pyrF GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS17585 Bacteria 2GKWK@201174,4CZAK@85004,COG0284@1,COG0284@2 NA|NA|NA F Belongs to the OMP decarboxylase family. Type 2 subfamily NIBLCNGB_00393 326426.Bbr_0977 1.6e-157 562.0 Bifidobacteriales pyrK 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 ko:K00266,ko:K00528,ko:K02823 ko00240,ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00910,map01100,map01110,map01120,map01130,map01230 R00093,R00114,R00248,R10159 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 Bacteria 2HQ24@201174,4CZC1@85004,COG0543@1,COG0543@2 NA|NA|NA C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B NIBLCNGB_00394 326426.Bbr_0978 2.4e-181 641.3 Bifidobacteriales pyrD 1.3.1.14,1.3.98.1 ko:K00226,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKC6@201174,4CYU2@85004,COG0167@1,COG0167@2 NA|NA|NA F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily NIBLCNGB_00395 326426.Bbr_0979 5e-125 453.8 Bifidobacteriales pyrE 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM5A@201174,4CZHB@85004,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) NIBLCNGB_00396 216816.GS08_04970 9e-29 132.1 Bifidobacteriales Bacteria 2B3KJ@1,2GWXF@201174,31W9X@2,4D1NA@85004 NA|NA|NA NIBLCNGB_00397 326426.Bbr_0980 8.1e-218 762.7 Bifidobacteriales MA20_36090 Bacteria 2GMT6@201174,4CZ4Q@85004,COG1073@1,COG1073@2 NA|NA|NA S Psort location Cytoplasmic, score 8.87 NIBLCNGB_00398 326426.Bbr_0981 9.4e-172 609.4 Bifidobacteriales cpsY Bacteria 2HZCU@201174,4CZT8@85004,COG0583@1,COG0583@2 NA|NA|NA K Bacterial regulatory helix-turn-helix protein, lysR family NIBLCNGB_00399 326426.Bbr_0982 9.4e-123 446.0 Bifidobacteriales 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 R05287 RC00697 ko00000,ko00001,ko01000 Bacteria 2I8XE@201174,4D00B@85004,COG1011@1,COG1011@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase NIBLCNGB_00400 326426.Bbr_0983 0.0 1119.8 Bifidobacteriales nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 2GJHB@201174,4CZC5@85004,COG0062@1,COG0062@2,COG0063@1,COG0063@2 NA|NA|NA H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration NIBLCNGB_00401 326426.Bbr_0984 6.4e-301 1039.3 Bifidobacteriales ybiT Bacteria 2GKQ4@201174,4CYS2@85004,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter NIBLCNGB_00402 326426.Bbr_0985 2.4e-130 471.5 Bifidobacteriales Bacteria 2GMGQ@201174,4CZA7@85004,COG4221@1,COG4221@2 NA|NA|NA S Enoyl-(Acyl carrier protein) reductase NIBLCNGB_00403 326426.Bbr_0986 1.1e-127 462.6 Bifidobacteriales ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2GJ0M@201174,4D2W4@85004,COG1122@1,COG1122@2 NA|NA|NA P ABC transporter NIBLCNGB_00404 1437610.BREU_0057 1.5e-14 84.7 Bifidobacteriales XK26_04485 ko:K16785 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2IDZ2@201174,4D0CV@85004,COG0619@1,COG0619@2 NA|NA|NA P Cobalt transport protein NIBLCNGB_00405 326426.Bbr_0988 9.5e-233 812.4 Bifidobacteriales yhdR 2.6.1.1 ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 Bacteria 2GPM3@201174,4CZ6T@85004,COG0436@1,COG0436@2 NA|NA|NA E Psort location Cytoplasmic, score 8.87 NIBLCNGB_00406 326426.Bbr_0989 0.0 2024.2 Bifidobacteriales uvrA GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090 ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2GJUV@201174,4CYRU@85004,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate NIBLCNGB_00407 326426.Bbr_0990 0.0 1472.6 Bifidobacteriales uvrC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2GIS4@201174,4CYVX@85004,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision NIBLCNGB_00408 326426.Bbr_0991 1.6e-190 671.8 Bifidobacteriales aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2552c Bacteria 2GPQQ@201174,4CZCM@85004,COG0169@1,COG0169@2 NA|NA|NA E Shikimate dehydrogenase substrate binding domain NIBLCNGB_00409 326426.Bbr_0992 1.1e-178 632.5 Bifidobacteriales rapZ GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K06958 ko00000,ko03019 Bacteria 2GMWB@201174,4CZ70@85004,COG1660@1,COG1660@2 NA|NA|NA S Displays ATPase and GTPase activities NIBLCNGB_00410 326426.Bbr_0993 3.5e-169 600.9 Bifidobacteriales whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 ko:K09762 ko00000 Bacteria 2GJZU@201174,4CYTD@85004,COG1481@1,COG1481@2 NA|NA|NA K May be required for sporulation NIBLCNGB_00411 326426.Bbr_0994 1.9e-220 771.5 Bifidobacteriales pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJC6@201174,4CZJ3@85004,COG0126@1,COG0126@2 NA|NA|NA F Phosphoglycerate kinase NIBLCNGB_00412 326426.Bbr_0995 3.5e-146 524.2 Bifidobacteriales tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJXZ@201174,4CYSG@85004,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) NIBLCNGB_00413 326426.Bbr_0996 2.5e-34 151.0 Bifidobacteriales secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2GR31@201174,4D16U@85004,COG1314@1,COG1314@2 NA|NA|NA U Preprotein translocase SecG subunit NIBLCNGB_00414 326426.Bbr_0997 3.4e-177 627.5 Bifidobacteriales ldh GO:0003674,GO:0003824,GO:0004457,GO:0004459,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 2IASS@201174,4CZRT@85004,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily NIBLCNGB_00415 326426.Bbr_0998 2.9e-159 567.8 Bifidobacteriales Bacteria 2HZYB@201174,4CZQW@85004,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase NIBLCNGB_00416 326426.Bbr_0999 4e-300 1036.6 Bifidobacteriales alaA GO:0003674,GO:0003824,GO:0004021,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0019842,GO:0030170,GO:0030632,GO:0032787,GO:0033554,GO:0036094,GO:0040007,GO:0042221,GO:0042851,GO:0042852,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0046677,GO:0047635,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.2,2.6.1.66 ko:K00814,ko:K14260 ko00220,ko00250,ko00290,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00220,map00250,map00290,map00710,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00171 R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 iNJ661.Rv0337c Bacteria 2GJ7R@201174,4CZVJ@85004,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase, class I II NIBLCNGB_00417 326426.Bbr_1000 1.7e-186 658.7 Bifidobacteriales Bacteria 29VGS@1,2GXVQ@201174,30GYC@2,4D1QB@85004 NA|NA|NA NIBLCNGB_00418 326426.Bbr_1001 4e-240 837.0 Bifidobacteriales brnQ ko:K03311 ko00000 2.A.26 Bacteria 2GNMD@201174,4CZIP@85004,COG1114@1,COG1114@2 NA|NA|NA U Component of the transport system for branched-chain amino acids NIBLCNGB_00419 216816.GS08_05525 3.6e-202 710.7 Bifidobacteriales tal GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016832,GO:0044424,GO:0044464,GO:0097023 2.2.1.2 ko:K00616,ko:K08313,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 iB21_1397.B21_03781,iEC042_1314.EC042_0914,iECBD_1354.ECBD_4077,iECB_1328.ECB_03832,iECD_1391.ECD_03832,iECH74115_1262.ECH74115_5407,iECSP_1301.ECSP_5016,iECs_1301.ECs4875,iEcHS_1320.EcHS_A4181,iG2583_1286.G2583_4758,iSBO_1134.SBO_0715,iSF_1195.SF0775,iSFxv_1172.SFxv_0845,iS_1188.S0818,iZ_1308.Z5501 Bacteria 2GMF9@201174,4CZ3J@85004,COG0176@1,COG0176@2 NA|NA|NA H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway NIBLCNGB_00420 326426.Bbr_1003 0.0 1413.3 Bifidobacteriales tkt GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ1K@201174,4CZ64@85004,COG0021@1,COG0021@2 NA|NA|NA H Belongs to the transketolase family NIBLCNGB_00421 326426.Bbr_1004 3.7e-191 674.1 Bifidobacteriales hrcA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K03705 ko00000,ko03000 Bacteria 2GKF5@201174,4CZK3@85004,COG1420@1,COG1420@2 NA|NA|NA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons NIBLCNGB_00422 326426.Bbr_1005 2.6e-211 741.1 Bifidobacteriales dnaJ GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K03686 ko00000,ko03029,ko03110 Bacteria 2GK69@201174,4D03K@85004,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins NIBLCNGB_00424 404380.Gbem_3471 6.1e-75 287.7 Deltaproteobacteria sppA ko:K04773 ko00000,ko01000,ko01002 Bacteria 1MY1I@1224,2WSJ6@28221,42PFB@68525,COG0616@1,COG0616@2 NA|NA|NA OU Serine dehydrogenase proteinase NIBLCNGB_00425 1437610.BREU_1266 2.2e-16 92.8 Actinobacteria Bacteria 2GZ09@201174,COG5479@1,COG5479@2 NA|NA|NA M peptidoglycan receptor activity NIBLCNGB_00426 1437609.BCAL_0101 6.6e-244 849.7 Bifidobacteriales Bacteria 2IBDV@201174,4CZS6@85004,COG4584@1,COG4584@2 NA|NA|NA L PFAM Integrase catalytic NIBLCNGB_00427 326426.Bbr_1401 2.2e-134 485.0 Bifidobacteriales Bacteria 2I90G@201174,4D05J@85004,COG1484@1,COG1484@2 NA|NA|NA L IstB-like ATP binding protein NIBLCNGB_00428 702459.BBPR_0930 2e-27 129.0 Bifidobacteriales Bacteria 2DRCI@1,2GPSH@201174,33B7V@2,4D1E1@85004 NA|NA|NA S SPP1 phage holin NIBLCNGB_00430 566552.BIFCAT_00857 3.6e-08 64.3 Bifidobacteriales Bacteria 2BDBJ@1,2HCKW@201174,3270A@2,4D2JW@85004 NA|NA|NA NIBLCNGB_00431 411473.RUMCAL_00420 3.3e-22 114.4 Clostridia sca1 Bacteria 1W3W2@1239,254XE@186801,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation NIBLCNGB_00432 1435051.BMOU_0765 6.2e-131 474.2 Bifidobacteriales Bacteria 2EPQN@1,2IA76@201174,33HB6@2,4D0AV@85004 NA|NA|NA NIBLCNGB_00433 1692.BMAGN_1457 3.1e-45 189.1 Bifidobacteriales Bacteria 2B163@1,2IGP1@201174,31TK5@2,4D129@85004 NA|NA|NA NIBLCNGB_00434 1394176.AWUO01000014_gene652 4.7e-67 261.5 Bifidobacteriales Bacteria 2A0PS@1,2IHAD@201174,30NU3@2,4D0Q4@85004 NA|NA|NA NIBLCNGB_00435 398513.BBNG_00858 6e-192 678.3 Bifidobacteriales Bacteria 2I92I@201174,4D030@85004,COG5283@1,COG5283@2 NA|NA|NA S Phage-related minor tail protein NIBLCNGB_00436 398513.BBNG_00857 3e-34 151.0 Bifidobacteriales Bacteria 2BMIJ@1,2H1C7@201174,32G3G@2,4D1RU@85004 NA|NA|NA NIBLCNGB_00437 702459.BBPR_0921 2.1e-56 225.3 Bifidobacteriales Bacteria 2BDK2@1,2HCXD@201174,3279G@2,4D2PB@85004 NA|NA|NA NIBLCNGB_00438 702459.BBPR_0920 1.3e-80 305.8 Bifidobacteriales Bacteria 2EMRF@1,2GR0S@201174,33FDY@2,4D1HP@85004 NA|NA|NA NIBLCNGB_00439 398513.BBNG_00854 2.3e-40 171.8 Bifidobacteriales Bacteria 2B64Z@1,2H1JX@201174,31Z1W@2,4D1RV@85004 NA|NA|NA NIBLCNGB_00440 398513.BBNG_00853 4.5e-38 164.1 Bifidobacteriales Bacteria 2EPKQ@1,2ISZ5@201174,33H7B@2,4D1CJ@85004 NA|NA|NA NIBLCNGB_00441 398513.BBNG_00852 1.2e-52 212.6 Bifidobacteriales Bacteria 2DY8F@1,2GRSW@201174,348MB@2,4D1II@85004 NA|NA|NA NIBLCNGB_00442 1680.BADO_1239 1.6e-60 239.2 Actinobacteria Bacteria 2DXEY@1,2IJBW@201174,344QE@2 NA|NA|NA NIBLCNGB_00443 1288079.AUKN01000018_gene2477 3.5e-80 305.1 Actinobacteria Bacteria 28JC4@1,2IEPB@201174,2Z96S@2 NA|NA|NA S P22 coat protein-protein 5 domain protein NIBLCNGB_00444 68199.JNZO01000025_gene5829 2.2e-23 115.9 Actinobacteria Bacteria 2EPXN@1,2IFJX@201174,33HI6@2 NA|NA|NA NIBLCNGB_00445 1680.BADO_1242 2.4e-100 372.5 Bifidobacteriales Bacteria 2BXAC@1,2I8IX@201174,2Z85S@2,4D2PT@85004 NA|NA|NA NIBLCNGB_00446 1680.BADO_1243 4.6e-168 597.8 Bifidobacteriales Bacteria 2C9AC@1,2I07F@201174,2Z7TR@2,4D2I2@85004 NA|NA|NA S Phage portal protein, SPP1 Gp6-like NIBLCNGB_00447 1680.BADO_1244 5.8e-99 367.1 Actinobacteria Bacteria 2GNSB@201174,COG4626@1,COG4626@2 NA|NA|NA S Terminase NIBLCNGB_00448 1680.BADO_1247 2.1e-165 588.6 Actinobacteria Bacteria 2GNSB@201174,COG4626@1,COG4626@2 NA|NA|NA S Terminase NIBLCNGB_00449 1680.BADO_1248 1.3e-27 129.8 Bifidobacteriales Bacteria 2EIV5@1,2GPKM@201174,331JY@2,4D2F7@85004 NA|NA|NA NIBLCNGB_00450 1437608.BBIA_0622 3.6e-51 207.6 Bifidobacteriales ko:K07451 ko00000,ko01000,ko02048 Bacteria 2FBQW@1,2GQHP@201174,343VS@2,4D2A9@85004 NA|NA|NA NIBLCNGB_00452 158787.BSCA_1015 3.7e-28 130.2 Bifidobacteriales Bacteria 2GQY8@201174,4D1IJ@85004,COG3311@1,COG3311@2 NA|NA|NA K Transcriptional regulator NIBLCNGB_00453 158787.BSCA_0747 7.1e-91 340.5 Bifidobacteriales Bacteria 2GW8Y@201174,4D1FV@85004,COG2023@1,COG2023@2 NA|NA|NA J tRNA 5'-leader removal NIBLCNGB_00459 1437609.BCAL_0154 3.7e-36 158.3 Bifidobacteriales ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2IM4T@201174,4D15Z@85004,COG1949@1,COG1949@2 NA|NA|NA A 3'-to-5' exoribonuclease specific for small oligoribonucleotides NIBLCNGB_00461 158787.BSCA_1022 4.1e-63 247.3 Bifidobacteriales Bacteria 2GQKB@201174,4D1JQ@85004,COG1403@1,COG1403@2 NA|NA|NA V HNH endonuclease NIBLCNGB_00463 158787.BSCA_1895 3.9e-84 318.9 Bifidobacteriales ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 2I9G6@201174,4D06E@85004,COG1475@1,COG1475@2 NA|NA|NA K ParB-like nuclease domain NIBLCNGB_00464 1435051.BMOU_0254 1.5e-12 79.3 Bifidobacteriales Bacteria 2BEW9@1,2HEFE@201174,328MX@2,4D2QV@85004 NA|NA|NA NIBLCNGB_00465 78345.BMERY_1436 1.5e-55 222.6 Bifidobacteriales ssb1 ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 2GMM3@201174,4CZ5V@85004,COG0629@1,COG0629@2 NA|NA|NA L Single-stranded DNA-binding protein NIBLCNGB_00471 702459.BBPR_0882 4e-17 95.1 Bifidobacteriales Bacteria 29F22@1,2HDWQ@201174,301ZU@2,4D2IC@85004 NA|NA|NA NIBLCNGB_00474 566552.BIFCAT_00892 3.1e-39 168.7 Bifidobacteriales Bacteria 2B5QH@1,2I00Z@201174,31YK2@2,4D2K0@85004 NA|NA|NA NIBLCNGB_00476 1437608.BBIA_0648 2.1e-10 72.0 Bifidobacteriales Bacteria 2BK5H@1,2HBVM@201174,32EJ4@2,4D2NH@85004 NA|NA|NA NIBLCNGB_00477 762211.BSTEL_1987 4.5e-119 434.5 Bifidobacteriales Bacteria 2IA5J@201174,4D0WF@85004,COG3943@1,COG3943@2 NA|NA|NA S Virulence protein RhuM family NIBLCNGB_00478 158787.BSCA_0773 7.4e-55 219.9 Bifidobacteriales Bacteria 2C5TS@1,2IT81@201174,2ZX0Y@2,4D1BF@85004 NA|NA|NA NIBLCNGB_00479 31954.BPSP_0858 2.8e-63 248.8 Actinobacteria Bacteria 2EUST@1,2GVYA@201174,33N8C@2 NA|NA|NA NIBLCNGB_00480 398513.BBNG_00808 2.7e-29 135.6 Bifidobacteriales Bacteria 2HZZA@201174,4D2CH@85004,COG5346@1,COG5346@2 NA|NA|NA S Predicted membrane protein (DUF2335) NIBLCNGB_00481 1437609.BCAL_1183 6.7e-114 417.5 Bifidobacteriales Bacteria 2HD2H@201174,4D2VK@85004,COG4974@1,COG4974@2 NA|NA|NA L Phage integrase family NIBLCNGB_00482 326426.Bbr_1006 4.8e-156 557.0 Bifidobacteriales Bacteria 2GW7W@201174,4CZ4W@85004,COG3001@1,COG3001@2 NA|NA|NA G Fructosamine kinase NIBLCNGB_00483 326426.Bbr_1007 1.8e-156 558.5 Bifidobacteriales uppP 3.6.1.27 ko:K06153 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 2GJVG@201174,4CZ83@85004,COG1968@1,COG1968@2 NA|NA|NA V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin NIBLCNGB_00484 216816.GS08_05495 1.2e-133 482.6 Bifidobacteriales ko:K07184 ko00000 Bacteria 2GK10@201174,4CYSJ@85004,COG1938@1,COG1938@2 NA|NA|NA S PAC2 family NIBLCNGB_00490 326426.Bbr_1009 0.0 1369.8 Bifidobacteriales thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GKTC@201174,4CZD3@85004,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) NIBLCNGB_00491 326426.Bbr_1010 2.6e-111 407.9 Bifidobacteriales hit GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 ko:K19710 ko00230,map00230 R00126,R01618 RC00002,RC02753,RC02795 ko00000,ko00001,ko01000 Bacteria 2GJT5@201174,4CZS7@85004,COG0537@1,COG0537@2 NA|NA|NA FG HIT domain NIBLCNGB_00492 326426.Bbr_1011 2e-111 408.7 Bifidobacteriales yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 Bacteria 2GJ4G@201174,4CZ9X@85004,COG0217@1,COG0217@2 NA|NA|NA K transcriptional regulatory protein NIBLCNGB_00493 326426.Bbr_1012 2.7e-100 371.3 Bifidobacteriales ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJI5@201174,4CZ79@85004,COG0817@1,COG0817@2 NA|NA|NA L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group NIBLCNGB_00494 326426.Bbr_1013 9.4e-107 392.9 Bifidobacteriales ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GN17@201174,4CZCE@85004,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB NIBLCNGB_00495 326426.Bbr_1014 4.7e-199 700.3 Bifidobacteriales ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJZF@201174,4CZGU@85004,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing NIBLCNGB_00496 326426.Bbr_1015 2.8e-52 211.5 Bifidobacteriales yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2IKUJ@201174,4D139@85004,COG1862@1,COG1862@2 NA|NA|NA U Preprotein translocase subunit NIBLCNGB_00497 326426.Bbr_1016 2.7e-100 371.3 Bifidobacteriales apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko04147 Bacteria 2IM7C@201174,4CZ9H@85004,COG0503@1,COG0503@2 NA|NA|NA F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis NIBLCNGB_00498 326426.Bbr_1017 6.9e-223 779.6 Bifidobacteriales sucC 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKSB@201174,4CZCQ@85004,COG0045@1,COG0045@2 NA|NA|NA F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit NIBLCNGB_00499 326426.Bbr_1018 2.9e-165 587.8 Bifidobacteriales sucD GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK00@201174,4CYX1@85004,COG0074@1,COG0074@2 NA|NA|NA C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit NIBLCNGB_00500 326426.Bbr_1019 4.7e-233 813.5 Bifidobacteriales GO:0008150,GO:0040007 Bacteria 2EKVE@1,2HZ8H@201174,33EIZ@2,4CYRN@85004 NA|NA|NA NIBLCNGB_00501 326426.Bbr_1020 2.3e-311 1073.5 Bifidobacteriales purH GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS04230,iJN678.purH Bacteria 2GJWU@201174,4CZ3P@85004,COG0138@1,COG0138@2 NA|NA|NA F Bifunctional purine biosynthesis protein PurH NIBLCNGB_00502 762211.BSTEL_0211 4.1e-31 140.6 Bifidobacteriales Bacteria 2AXAE@1,2IQKC@201174,31P9H@2,4D18B@85004 NA|NA|NA NIBLCNGB_00503 326426.Bbr_1021 2.3e-117 428.7 Bifidobacteriales glpF ko:K02440,ko:K06188 ko00000,ko02000 1.A.8,1.A.8.1,1.A.8.2 Bacteria 2HZ9W@201174,4CZ5Q@85004,COG0580@1,COG0580@2 NA|NA|NA U Belongs to the MIP aquaporin (TC 1.A.8) family NIBLCNGB_00504 326426.Bbr_1022 4.5e-143 513.8 Bifidobacteriales rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 ko00000,ko01000,ko03009 Bacteria 2GJ4N@201174,4CZGG@85004,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family NIBLCNGB_00505 326426.Bbr_1023 0.0 1370.5 Bifidobacteriales der GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0030312,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.1.1.399,1.1.1.95,2.7.4.25 ko:K00058,ko:K00945,ko:K03977 ko00240,ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00240,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020,M00052 R00158,R00512,R01513,R01665 RC00002,RC00031 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 Bacteria 2GJ8J@201174,4CYSE@85004,COG0283@1,COG0283@2,COG1160@1,COG1160@2 NA|NA|NA F GTPase that plays an essential role in the late steps of ribosome biogenesis NIBLCNGB_00507 326426.Bbr_1024 1.6e-162 578.6 Bifidobacteriales supH Bacteria 2HZBZ@201174,4CZNM@85004,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase NIBLCNGB_00508 326426.Bbr_1025 2.5e-291 1007.3 Bifidobacteriales ugpA 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2I2G3@201174,4CYTQ@85004,COG4284@1,COG4284@2 NA|NA|NA G UTP-glucose-1-phosphate uridylyltransferase NIBLCNGB_00509 326426.Bbr_1026 0.0 1229.9 Bifidobacteriales pafB ko:K13573 ko00000,ko03051 Bacteria 2I8M5@201174,4CZWF@85004,COG2378@1,COG2378@2 NA|NA|NA K WYL domain NIBLCNGB_00510 326426.Bbr_1027 6.8e-53 213.0 Bifidobacteriales Bacteria 2B5BE@1,2IQT5@201174,31Y5K@2,4D17A@85004 NA|NA|NA NIBLCNGB_00511 326426.Bbr_1028 0.0 1706.8 Bifidobacteriales helY GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 ko:K03727 ko00000,ko01000 Bacteria 2GJEX@201174,4CZEC@85004,COG4581@1,COG4581@2 NA|NA|NA L DEAD DEAH box helicase NIBLCNGB_00512 326426.Bbr_1029 5.1e-62 243.4 Bifidobacteriales rbpA GO:0001000,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0043167,GO:0043169,GO:0043175,GO:0045893,GO:0045935,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 Bacteria 2CNY9@1,2IMK6@201174,32SI2@2,4D0V5@85004 NA|NA|NA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters NIBLCNGB_00513 326426.Bbr_1030 5.7e-140 503.4 Bifidobacteriales pgp GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0071704,GO:0140096,GO:1901564 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 2HFGX@201174,4CYSF@85004,COG0546@1,COG0546@2 NA|NA|NA S HAD-hyrolase-like NIBLCNGB_00514 326426.Bbr_1031 2.6e-35 154.1 Bifidobacteriales Bacteria 2BB9R@1,2H9QN@201174,324SH@2,4D2DN@85004 NA|NA|NA NIBLCNGB_00515 326426.Bbr_1032 1.3e-64 252.3 Bifidobacteriales Bacteria 29TZI@1,2ISJH@201174,30F8H@2,4D0Z6@85004 NA|NA|NA NIBLCNGB_00516 326426.Bbr_1033 1.1e-110 406.0 Bifidobacteriales Bacteria 2GM67@201174,4CZ0X@85004,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance NIBLCNGB_00517 326426.Bbr_1034 2.6e-74 284.6 Bifidobacteriales garA Bacteria 2GK99@201174,4D0R3@85004,COG1716@1,COG1716@2 NA|NA|NA T Inner membrane component of T3SS, cytoplasmic domain NIBLCNGB_00518 326426.Bbr_1035 2.2e-140 505.0 Bifidobacteriales GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 Bacteria 2GJ3C@201174,4CYYH@85004,COG3879@1,COG3879@2 NA|NA|NA S Bacterial protein of unknown function (DUF881) NIBLCNGB_00519 326426.Bbr_1036 3.9e-35 154.1 Bifidobacteriales sbp Bacteria 2IKJW@201174,4D12G@85004,COG3856@1,COG3856@2 NA|NA|NA S Protein of unknown function (DUF1290) NIBLCNGB_00520 326426.Bbr_1037 1.6e-169 602.1 Bifidobacteriales GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 Bacteria 2GMS5@201174,4CZ72@85004,COG3879@1,COG3879@2 NA|NA|NA S Bacterial protein of unknown function (DUF881) NIBLCNGB_00521 326426.Bbr_1038 1.6e-103 382.1 Bifidobacteriales pgsA GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 Bacteria 2GM3F@201174,4CZGD@85004,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family NIBLCNGB_00522 326426.Bbr_1039 1.1e-155 555.8 Bifidobacteriales hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNAX@201174,4CZ66@85004,COG0040@1,COG0040@2 NA|NA|NA F ATP phosphoribosyltransferase NIBLCNGB_00523 326426.Bbr_1040 9.9e-42 175.6 Bifidobacteriales hisE GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16 ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04640 RC00002,RC00945,RC01055 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_0880,iECW_1372.ECW_m2186,iEKO11_1354.EKO11_1768,iSB619.SA_RS14110,iUMN146_1321.UM146_06665,iWFL_1372.ECW_m2186,iYO844.BSU34860 Bacteria 2IQ4D@201174,4D108@85004,COG0140@1,COG0140@2 NA|NA|NA E Phosphoribosyl-ATP pyrophosphohydrolase NIBLCNGB_00524 326426.Bbr_1041 9.4e-113 412.9 Bifidobacteriales rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783,ko:K17195 ko00030,ko00040,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529,R09031 RC00540,RC03111 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJZ9@201174,4CYX0@85004,COG0036@1,COG0036@2 NA|NA|NA G Ribulose-phosphate 3-epimerase NIBLCNGB_00525 326426.Bbr_1042 5.3e-186 656.8 Bifidobacteriales lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 ko:K03438,ko:K13292 ko00000,ko01000,ko03009 Bacteria 2GKSS@201174,4CYV8@85004,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins NIBLCNGB_00526 326426.Bbr_1043 1e-159 569.3 Bifidobacteriales trpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN6T@201174,4D0A3@85004,COG0159@1,COG0159@2 NA|NA|NA E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate NIBLCNGB_00527 326426.Bbr_1044 0.0 1352.4 Bifidobacteriales trpB GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48,4.2.1.20 ko:K01609,ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722,R03508 RC00209,RC00210,RC00700,RC00701,RC00944,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM7Z@201174,4CZJW@85004,COG0133@1,COG0133@2,COG0134@1,COG0134@2 NA|NA|NA E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine NIBLCNGB_00528 326426.Bbr_1045 1e-127 462.6 Bifidobacteriales Bacteria 2GKY8@201174,4CZPW@85004,COG2135@1,COG2135@2 NA|NA|NA S SOS response associated peptidase (SRAP) NIBLCNGB_00529 326426.Bbr_1046 1.4e-156 558.9 Bifidobacteriales nfo GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJJQ@201174,4CZ0H@85004,COG0648@1,COG0648@2 NA|NA|NA L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin NIBLCNGB_00530 326426.Bbr_1047 5.3e-259 899.8 Bifidobacteriales mmuP GO:0000096,GO:0000097,GO:0000100,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0015806,GO:0016020,GO:0016053,GO:0019752,GO:0022857,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682 ko:K02205,ko:K03293,ko:K16235,ko:K16236 ko00000,ko02000 2.A.3.1,2.A.3.1.10 Bacteria 2I2DX@201174,4D2V7@85004,COG0833@1,COG0833@2 NA|NA|NA E amino acid NIBLCNGB_00531 326426.Bbr_1048 8.5e-93 346.7 Bifidobacteriales Bacteria 2I8QF@201174,4CZF1@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily NIBLCNGB_00532 216816.GS08_05265 1.8e-187 661.8 Bifidobacteriales Bacteria 2H595@201174,4CZBZ@85004,COG4767@1,COG4767@2 NA|NA|NA V VanZ like family NIBLCNGB_00533 749414.SBI_00921 7.8e-69 267.3 Actinobacteria cefD 5.1.1.17 ko:K04127,ko:K11325,ko:K21174 ko00311,ko01059,ko01100,ko01130,map00311,map01059,map01100,map01130 M00673,M00825 R04147 RC00302 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNM2@201174,COG0520@1,COG0520@2 NA|NA|NA E Aminotransferase, class V NIBLCNGB_00534 158787.BSCA_1856 8.7e-34 149.4 Bifidobacteriales Bacteria 2IPTA@201174,4D10S@85004,COG4367@1,COG4367@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2316) NIBLCNGB_00535 216816.GS08_05230 3.3e-100 370.9 Bifidobacteriales Bacteria 2HEQC@201174,4D0EK@85004,COG3981@1,COG3981@2 NA|NA|NA S Acetyltransferase (GNAT) domain NIBLCNGB_00536 326426.Bbr_1056 1.5e-50 205.3 Bifidobacteriales Bacteria 2B0WB@1,2GRYR@201174,31T91@2,4D1GV@85004 NA|NA|NA NIBLCNGB_00537 326426.Bbr_1057 5.2e-121 440.3 Bifidobacteriales Bacteria 2IPD5@201174,333S7@2,4CZX8@85004,arCOG08992@1 NA|NA|NA NIBLCNGB_00540 158787.BSCA_2269 2e-35 156.4 Bifidobacteriales 2.7.13.3 ko:K07675,ko:K20263 ko02020,ko02024,map02020,map02024 M00473,M00818 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2GVWR@201174,4D03H@85004,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase NIBLCNGB_00541 326426.Bbr_1060 5.8e-203 713.4 Bifidobacteriales 2.7.13.3 ko:K07675,ko:K20263 ko02020,ko02024,map02020,map02024 M00473,M00818 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2GVWR@201174,4D03H@85004,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase NIBLCNGB_00542 216816.GS08_05195 5.3e-127 460.3 Bifidobacteriales Bacteria 2IAQ5@201174,4D0E3@85004,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon NIBLCNGB_00543 216816.GS08_05190 3e-95 354.4 Bifidobacteriales Bacteria 2DCFI@1,2GWSG@201174,2ZDXV@2,4D1VT@85004 NA|NA|NA NIBLCNGB_00544 216816.GS08_05185 3.6e-144 517.7 Bifidobacteriales ko:K02005,ko:K02022 ko00000 Bacteria 2IFY7@201174,4D13B@85004,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family NIBLCNGB_00545 326426.Bbr_1064 1.4e-124 452.2 Bifidobacteriales lolD ko:K02003,ko:K09810 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 Bacteria 2I5GS@201174,4D2XS@85004,COG4181@1,COG4181@2 NA|NA|NA Q ATPases associated with a variety of cellular activities NIBLCNGB_00546 216816.GS08_05175 2.7e-176 624.8 Bifidobacteriales ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2HXTZ@201174,4CZYZ@85004,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain NIBLCNGB_00547 326426.Bbr_1066 3.2e-40 170.6 Bifidobacteriales relB ko:K07473,ko:K18918 ko00000,ko02048,ko03000 Bacteria 2GV25@201174,4D179@85004,COG3077@1,COG3077@2 NA|NA|NA L RelB antitoxin NIBLCNGB_00548 326426.Bbr_1067 3.2e-49 200.7 Bifidobacteriales ko:K19157 ko00000,ko01000,ko02048 Bacteria 2GSX9@201174,4D1AZ@85004,COG3041@1,COG3041@2 NA|NA|NA S Bacterial toxin of type II toxin-antitoxin system, YafQ NIBLCNGB_00549 158787.BSCA_2269 5.1e-26 123.6 Bifidobacteriales 2.7.13.3 ko:K07675,ko:K20263 ko02020,ko02024,map02020,map02024 M00473,M00818 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2GVWR@201174,4D03H@85004,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase NIBLCNGB_00550 326426.Bbr_1068 8e-94 349.7 Bifidobacteriales rpoE4 ko:K03088 ko00000,ko03021 Bacteria 2HG2H@201174,4D1CQ@85004,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70 region 2 NIBLCNGB_00551 649743.HMPREF0972_00937 2.1e-21 109.8 Actinobacteria Bacteria 29ZK4@1,2GWY0@201174,30MKH@2,4D73R@85005 NA|NA|NA S Psort location CytoplasmicMembrane, score NIBLCNGB_00552 326426.Bbr_1070 4.7e-106 390.6 Bifidobacteriales Bacteria 2AYSN@1,2ISV3@201174,31QXY@2,4D18V@85004 NA|NA|NA NIBLCNGB_00553 326426.Bbr_1071 5.8e-138 496.9 Bifidobacteriales ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2B5A1@1,2HZNW@201174,31Y46@2,4D13D@85004 NA|NA|NA NIBLCNGB_00554 326426.Bbr_1072 4.9e-170 603.6 Bifidobacteriales yfiL ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GNQJ@201174,4D0SJ@85004,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities NIBLCNGB_00555 326426.Bbr_1073 6.9e-71 273.1 Bifidobacteriales Bacteria 2B3VD@1,2IS1C@201174,31QFH@2,4D1BE@85004 NA|NA|NA NIBLCNGB_00556 326426.Bbr_1074 1.4e-62 245.4 Bifidobacteriales Bacteria 2B7KG@1,2H4J4@201174,320RD@2,4D260@85004 NA|NA|NA NIBLCNGB_00557 216816.GS08_05150 5.3e-148 530.4 Bifidobacteriales ko:K11939 ko00000,ko02000 2.A.7.3.6 Bacteria 2GJKB@201174,4D03A@85004,COG5006@1,COG5006@2 NA|NA|NA S EamA-like transporter family NIBLCNGB_00558 216816.GS08_05145 1.7e-79 302.0 Bifidobacteriales Bacteria 2F10A@1,2IAKS@201174,33U1T@2,4D01S@85004 NA|NA|NA NIBLCNGB_00559 216816.GS08_05135 1.8e-53 215.3 Bifidobacteriales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IEJK@201174,4D0K4@85004,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities NIBLCNGB_00560 326426.Bbr_0152 2.8e-295 1020.4 Bifidobacteriales Bacteria 2IBDV@201174,4CZS6@85004,COG4584@1,COG4584@2 NA|NA|NA L PFAM Integrase catalytic NIBLCNGB_00561 326426.Bbr_0151 3.6e-148 530.8 Bifidobacteriales Bacteria 2H714@201174,4CZRM@85004,COG1484@1,COG1484@2 NA|NA|NA L IstB-like ATP binding protein NIBLCNGB_00562 216816.GS08_05135 7.2e-60 236.5 Bifidobacteriales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IEJK@201174,4D0K4@85004,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities NIBLCNGB_00563 327277.JHAL01000003_gene1823 8.8e-16 89.0 Bifidobacteriales fic GO:0008150,GO:0050789,GO:0050794,GO:0051302,GO:0065007 ko:K04095 ko00000,ko03036 Bacteria 2IN0D@201174,4D03T@85004,COG2184@1,COG2184@2 NA|NA|NA D Fic/DOC family NIBLCNGB_00564 216816.GS08_05125 4.1e-23 113.2 Actinobacteria Bacteria 2DEMJ@1,2GZR5@201174,2ZNGD@2 NA|NA|NA NIBLCNGB_00565 216816.GS08_05120 7.9e-109 399.8 Bifidobacteriales Bacteria 2BNX6@1,2GQ6P@201174,32HM5@2,4D027@85004 NA|NA|NA NIBLCNGB_00566 216816.GS08_05115 1.3e-45 188.7 Bacteria ko:K20391 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria COG1396@1,COG1396@2 NA|NA|NA K sequence-specific DNA binding NIBLCNGB_00567 326426.Bbr_1088 4.1e-33 146.7 Bacteria hipA GO:0000166,GO:0000287,GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0004672,GO:0004674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009279,GO:0009297,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015267,GO:0015288,GO:0015473,GO:0016020,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018105,GO:0018193,GO:0018209,GO:0019219,GO:0019222,GO:0019538,GO:0019867,GO:0022607,GO:0022611,GO:0022803,GO:0022829,GO:0022857,GO:0030030,GO:0030031,GO:0030312,GO:0030313,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031975,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0042710,GO:0043086,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043565,GO:0043711,GO:0044010,GO:0044085,GO:0044092,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044462,GO:0044464,GO:0044764,GO:0045892,GO:0045934,GO:0046777,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051252,GO:0051253,GO:0051704,GO:0055085,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140096,GO:0140110,GO:1901265,GO:1901363,GO:1901564,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 2.7.11.1 ko:K07154 ko00000,ko01000,ko01001,ko02048 Bacteria COG3550@1,COG3550@2 NA|NA|NA S kinase activity NIBLCNGB_00568 1437610.BREU_1320 4.5e-50 204.9 Bifidobacteriales Bacteria 2GJZG@201174,4CZ93@85004,COG2211@1,COG2211@2 NA|NA|NA G Transporter major facilitator family protein NIBLCNGB_00569 326426.Bbr_1090 3e-295 1020.4 Bifidobacteriales mmuP GO:0000096,GO:0000097,GO:0000100,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0015806,GO:0016020,GO:0016053,GO:0019752,GO:0022857,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682 ko:K02205,ko:K03293,ko:K16235,ko:K16236 ko00000,ko02000 2.A.3.1,2.A.3.1.10 Bacteria 2I2DX@201174,4D2V7@85004,COG0833@1,COG0833@2 NA|NA|NA E amino acid NIBLCNGB_00571 326426.Bbr_1092 4.3e-64 250.8 Bifidobacteriales yeaO Bacteria 2IQC0@201174,4D18P@85004,COG3189@1,COG3189@2 NA|NA|NA K Protein of unknown function, DUF488 NIBLCNGB_00572 326426.Bbr_1093 3.8e-75 287.3 Bifidobacteriales Bacteria 2ATA8@1,2IICV@201174,31IT9@2,4D0W4@85004 NA|NA|NA NIBLCNGB_00573 326426.Bbr_1094 5e-174 617.1 Bifidobacteriales 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2IF0U@201174,4D0I9@85004,COG2865@1,COG2865@2 NA|NA|NA NIBLCNGB_00574 326426.Bbr_1095 4e-65 253.8 Bifidobacteriales yijF ko:K09974 ko00000 Bacteria 2IBMJ@201174,4CZM2@85004,COG3738@1,COG3738@2 NA|NA|NA S Domain of unknown function (DUF1287) NIBLCNGB_00575 326426.Bbr_1096 9.9e-299 1031.9 Bifidobacteriales trpE 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKJT@201174,4CZHW@85004,COG0147@1,COG0147@2 NA|NA|NA E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia NIBLCNGB_00576 326426.Bbr_1097 1.5e-70 271.9 Bifidobacteriales hisI GO:0008150,GO:0040007 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1606 Bacteria 2IKKU@201174,4D0WW@85004,COG0139@1,COG0139@2 NA|NA|NA E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP NIBLCNGB_00577 326426.Bbr_1098 6.1e-140 503.4 Bifidobacteriales hisF GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007 4.1.3.27 ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023,M00026 R00985,R00986,R04558 RC00010,RC01190,RC01943,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIRP@201174,4CZ8Z@85004,COG0107@1,COG0107@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit NIBLCNGB_00578 216816.GS08_05710 1.6e-97 362.1 Bifidobacteriales 3.5.1.124 ko:K05520 ko00000,ko01000,ko01002 Bacteria 2GMMW@201174,4D0H3@85004,COG0693@1,COG0693@2 NA|NA|NA S DJ-1/PfpI family NIBLCNGB_00579 326426.Bbr_1100 1.6e-221 775.0 Bifidobacteriales rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 ko00000,ko01000,ko03009 Bacteria 2GJ48@201174,4CZG2@85004,COG0820@1,COG0820@2 NA|NA|NA J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs NIBLCNGB_00580 326426.Bbr_1101 1.8e-173 615.1 Bifidobacteriales cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41,2.7.7.67 ko:K00981,ko:K07098,ko:K19664 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799,R08966 RC00002 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1397 Bacteria 2I7ZA@201174,4CYZM@85004,COG0575@1,COG0575@2 NA|NA|NA I Cytidylyltransferase family NIBLCNGB_00581 326426.Bbr_1102 2.6e-92 344.7 Bifidobacteriales frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02838 ko00000,ko03012 Bacteria 2GJ9J@201174,4CYTF@85004,COG0233@1,COG0233@2 NA|NA|NA J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another NIBLCNGB_00582 326426.Bbr_1103 2.8e-134 484.6 Bifidobacteriales pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 iSB619.SA_RS06240 Bacteria 2GKWQ@201174,4CZEK@85004,COG0528@1,COG0528@2 NA|NA|NA F Catalyzes the reversible phosphorylation of UMP to UDP NIBLCNGB_00583 326426.Bbr_1104 1.4e-145 522.3 Bifidobacteriales tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02357 ko00000,ko03012,ko03029 Bacteria 2GK4M@201174,4CYVQ@85004,COG0264@1,COG0264@2 NA|NA|NA J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome NIBLCNGB_00584 326426.Bbr_1105 5.8e-144 516.9 Bifidobacteriales rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GMYC@201174,4CZ96@85004,COG0052@1,COG0052@2 NA|NA|NA J Belongs to the universal ribosomal protein uS2 family NIBLCNGB_00585 326426.Bbr_1106 1.7e-87 328.6 Bifidobacteriales def 3.5.1.88 ko:K01462 ko00000,ko01000 Bacteria 2GJ87@201174,4CZ63@85004,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions NIBLCNGB_00586 326426.Bbr_1107 0.0 1229.5 Bifidobacteriales fadD3 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2GIXQ@201174,4CYVD@85004,COG1022@1,COG1022@2 NA|NA|NA I long-chain-fatty acid CoA ligase NIBLCNGB_00587 326426.Bbr_1108 3.3e-91 340.9 Bifidobacteriales Bacteria 2BGJW@1,2IR97@201174,32AI7@2,4D19G@85004 NA|NA|NA NIBLCNGB_00588 326426.Bbr_1109 5.8e-208 729.9 Bifidobacteriales guaB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GKVS@201174,4CZDK@85004,COG0516@1,COG0516@2 NA|NA|NA F IMP dehydrogenase family protein NIBLCNGB_00589 326426.Bbr_1110 1.3e-242 845.1 Bifidobacteriales icd GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GM3D@201174,4CZ8V@85004,COG0538@1,COG0538@2 NA|NA|NA C Belongs to the isocitrate and isopropylmalate dehydrogenases family NIBLCNGB_00590 326426.Bbr_1111 1.7e-256 891.7 Bifidobacteriales ko:K10439,ko:K10546 ko02010,ko02030,map02010,map02030 M00212,M00216 ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.5 Bacteria 2HZAK@201174,4CZCR@85004,COG4213@1,COG4213@2 NA|NA|NA G ABC transporter substrate-binding protein NIBLCNGB_00591 326426.Bbr_1112 6.9e-36 156.0 Bifidobacteriales Bacteria 2IQ64@201174,4D199@85004,COG0739@1,COG0739@2 NA|NA|NA M Peptidase family M23 NIBLCNGB_00593 641146.HMPREF9020_01339 3.2e-175 620.9 Bifidobacteriales xerH ko:K04763 ko00000,ko03036 Bacteria 2IH6A@201174,4CZ62@85004,COG0582@1,COG0582@2,COG4974@1,COG4974@2 NA|NA|NA L Phage integrase family NIBLCNGB_00595 158787.BSCA_1053 4.1e-130 471.1 Bifidobacteriales ko:K09144 ko00000 Bacteria 2IHDQ@201174,4D0UC@85004,COG2253@1,COG2253@2 NA|NA|NA S Nucleotidyl transferase AbiEii toxin, Type IV TA system NIBLCNGB_00596 158787.BSCA_1054 1.6e-87 328.9 Bifidobacteriales Bacteria 2IMTJ@201174,4D150@85004,COG5340@1,COG5340@2 NA|NA|NA K Psort location Cytoplasmic, score NIBLCNGB_00597 326426.Bbr_1153 7.7e-102 377.1 Bifidobacteriales Bacteria 2ICFW@201174,4D01T@85004,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family NIBLCNGB_00602 326426.Bbr_1539 8.5e-55 221.1 Bifidobacteriales ard Bacteria 2ICX2@201174,4D0K8@85004,COG4734@1,COG4734@2 NA|NA|NA S Antirestriction protein (ArdA) NIBLCNGB_00604 1688.BCUN_0739 8.7e-84 317.4 Bifidobacteriales Bacteria 2I2GH@201174,4CZSM@85004,COG3583@1,COG3583@2,COG3942@1,COG3942@2 NA|NA|NA M G5 domain protein NIBLCNGB_00605 356829.BITS_1882 9.1e-69 267.3 Bifidobacteriales Bacteria 2B29P@1,2GUFB@201174,31UTG@2,4D1HY@85004 NA|NA|NA NIBLCNGB_00608 398513.BBNG_01183 1e-240 839.7 Bifidobacteriales topB 5.99.1.2 ko:K03169 ko00000,ko01000,ko03032 Bacteria 2GJU7@201174,4D044@85004,COG0550@1,COG0550@2 NA|NA|NA L DNA topoisomerase NIBLCNGB_00611 1688.BCUN_0733 1.3e-16 92.8 Bifidobacteriales Bacteria 2BI2K@1,2GR25@201174,32C7I@2,4D1ID@85004 NA|NA|NA K Bacterial mobilisation protein (MobC) NIBLCNGB_00612 411471.SUBVAR_07168 2.2e-36 159.8 Clostridia Bacteria 1TPD4@1239,24AYN@186801,COG3550@1,COG3550@2 NA|NA|NA S Pfam:CtkA_N NIBLCNGB_00614 1419583.V466_11885 6.3e-34 151.0 Gammaproteobacteria ecoRIIR 3.1.21.4 ko:K01155 ko00000,ko01000,ko02048 Bacteria 1R5NB@1224,1RN00@1236,2C4CB@1,2Z7XX@2 NA|NA|NA L EcoRII C terminal NIBLCNGB_00615 216816.GS08_05830 3.6e-140 504.2 Bifidobacteriales Bacteria 2GW8P@201174,4D1U2@85004,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family NIBLCNGB_00616 1688.BCUN_0730 3.9e-139 501.5 Bifidobacteriales Bacteria 2GPWU@201174,4CZXB@85004,COG0323@1,COG0323@2 NA|NA|NA L PFAM Relaxase mobilization nuclease family protein NIBLCNGB_00617 77635.BISU_0115 7.6e-87 327.8 Bifidobacteriales 2.7.11.1 ko:K07154 ko00000,ko01000,ko01001,ko02048 Bacteria 2IH51@201174,4D001@85004,COG3550@1,COG3550@2 NA|NA|NA S HipA-like C-terminal domain NIBLCNGB_00619 1688.BCUN_0723 1.1e-39 171.0 Bifidobacteriales Bacteria 2B5EX@1,2H0ER@201174,31Y9E@2,4D1TB@85004 NA|NA|NA NIBLCNGB_00620 356829.BITS_1851 2.5e-50 206.1 Bifidobacteriales Bacteria 2BGGQ@1,2GPXC@201174,32AER@2,4D1AU@85004 NA|NA|NA S Domain of unknown function (DUF4913) NIBLCNGB_00621 356829.BITS_1850 1.6e-231 808.9 Bifidobacteriales Bacteria 2GNQ7@201174,4D05X@85004,COG3505@1,COG3505@2 NA|NA|NA U TraM recognition site of TraD and TraG NIBLCNGB_00622 1193128.A200_01319 1.5e-22 113.2 Bifidobacteriales Bacteria 2ADU1@1,2HDBG@201174,313JQ@2,4D2MU@85004 NA|NA|NA NIBLCNGB_00623 909613.UO65_5304 1.1e-06 61.2 Pseudonocardiales Bacteria 2B0K8@1,2GRC0@201174,31SXX@2,4ED70@85010 NA|NA|NA NIBLCNGB_00626 1688.BCUN_0718 7.5e-201 706.8 Bifidobacteriales traD ko:K12071 ko00000,ko02044 3.A.7.11.1 Bacteria 2I70J@201174,4D08A@85004,COG0433@1,COG0433@2 NA|NA|NA S COG0433 Predicted ATPase NIBLCNGB_00627 356829.BITS_1878 8.3e-186 656.8 Bifidobacteriales Bacteria 28IPW@1,2HQJM@201174,2Z8PQ@2,4D0DF@85004 NA|NA|NA NIBLCNGB_00628 356829.BITS_1867 1.3e-141 510.4 Actinobacteria Bacteria 2D2AG@1,2I37G@201174,31S1J@2 NA|NA|NA NIBLCNGB_00629 356829.BITS_1866 1.7e-29 135.2 Bifidobacteriales Bacteria 2BFZK@1,2IR4J@201174,329VH@2,4D1C5@85004 NA|NA|NA NIBLCNGB_00630 356829.BITS_1865 6.9e-33 147.1 Bifidobacteriales Bacteria 2AP8J@1,2HZSS@201174,31EAI@2,4D1KR@85004 NA|NA|NA NIBLCNGB_00631 401473.BDP_0966 9.7e-07 61.6 Bifidobacteriales ko:K03646 ko00000,ko02000 2.C.1.2 Bacteria 2DDMI@1,2ICIR@201174,2ZIJN@2,4D112@85004 NA|NA|NA NIBLCNGB_00632 356829.BITS_1624 8e-21 107.5 Bifidobacteriales Bacteria 2BBDD@1,2H9W5@201174,324WG@2,4D2IY@85004 NA|NA|NA NIBLCNGB_00633 561180.BIFGAL_03249 0.0 1255.4 Bifidobacteriales XK27_00515 Bacteria 2HRQY@201174,4CYQ9@85004,COG3087@1,COG3087@2 NA|NA|NA D Cell surface antigen C-terminus NIBLCNGB_00634 1437610.BREU_2026 3.1e-38 166.0 Bifidobacteriales ko:K03646 ko00000,ko02000 2.C.1.2 Bacteria 2DDMI@1,2ICIR@201174,2ZIJN@2,4D00F@85004 NA|NA|NA NIBLCNGB_00635 401473.BDP_0972 4.5e-49 201.8 Bacteria Bacteria 2BTMH@1,32NU8@2 NA|NA|NA NIBLCNGB_00636 401473.BDP_0973 3.4e-22 110.5 Bacteria Bacteria 2EIAW@1,33C2A@2 NA|NA|NA NIBLCNGB_00638 1394176.AWUO01000011_gene383 8e-31 140.6 Bifidobacteriales parA ko:K03496 ko00000,ko03036,ko04812 Bacteria 2ICWE@201174,4D151@85004,COG1192@1,COG1192@2 NA|NA|NA D VirC1 protein NIBLCNGB_00641 1341695.BBOMB_0915 4.4e-16 91.3 Bifidobacteriales Bacteria 2B49D@1,2GY7H@201174,31X0M@2,4D1QU@85004 NA|NA|NA S Transcription factor WhiB NIBLCNGB_00642 401473.BDP_0914 7.5e-16 92.0 Bifidobacteriales Bacteria 29W79@1,2IC42@201174,30HSG@2,4CZZM@85004 NA|NA|NA S Helix-turn-helix domain NIBLCNGB_00648 547043.BIFPSEUDO_02912 2.7e-17 94.4 Bifidobacteriales Bacteria 2B56E@1,2H002@201174,31Y0A@2,4D1NU@85004 NA|NA|NA NIBLCNGB_00650 326426.Bbr_1123 5.2e-195 686.8 Bifidobacteriales tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 2GJ98@201174,4CZ0K@85004,COG0533@1,COG0533@2 NA|NA|NA O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction NIBLCNGB_00651 326426.Bbr_1124 3.8e-105 387.5 Bifidobacteriales rimI GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017189,GO:0018193,GO:0018194,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.3.1.128,2.3.1.234 ko:K01409,ko:K03789,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03009,ko03016 Bacteria 2IM9R@201174,4D0Q0@85004,COG0454@1,COG0456@2 NA|NA|NA K FR47-like protein NIBLCNGB_00652 326426.Bbr_1125 1e-159 569.3 Bifidobacteriales yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03016 Bacteria 2GMTM@201174,4D0A2@85004,COG1214@1,COG1214@2 NA|NA|NA O Glycoprotease family NIBLCNGB_00653 216816.GS08_05880 4e-88 330.9 Bifidobacteriales ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.1.221,5.1.1.1 ko:K01775,ko:K06925,ko:K07102 ko00473,ko00520,ko01100,ko01502,map00473,map00520,map01100,map01502 R00401,R08968,R11024 RC00002,RC00078,RC00285 ko00000,ko00001,ko01000,ko01011,ko03016 Bacteria 2IKV2@201174,4D0PH@85004,COG0802@1,COG0802@2 NA|NA|NA S Threonylcarbamoyl adenosine biosynthesis protein TsaE NIBLCNGB_00654 326426.Bbr_1127 9e-173 612.8 Bifidobacteriales holA 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GNMZ@201174,4CZ07@85004,COG1466@1,COG1466@2 NA|NA|NA L DNA polymerase III delta subunit NIBLCNGB_00655 326426.Bbr_1128 1.2e-310 1071.6 Bifidobacteriales comE ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 2GJGR@201174,4CZ6X@85004,COG0658@1,COG0658@2 NA|NA|NA S Competence protein NIBLCNGB_00656 326426.Bbr_1129 1.6e-44 185.7 Bifidobacteriales comEA 2.4.1.21 ko:K00703,ko:K02237,ko:K02238 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00429,M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003,ko02044 3.A.11.1,3.A.11.2 GT5 Bacteria 2IQDC@201174,4D176@85004,COG1555@1,COG1555@2 NA|NA|NA L Helix-hairpin-helix motif NIBLCNGB_00657 326426.Bbr_1130 0.0 2053.9 Bifidobacteriales leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2GJI1@201174,4CZHV@85004,COG0495@1,COG0495@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family NIBLCNGB_00658 326426.Bbr_1131 2.7e-160 571.2 Bifidobacteriales ko:K10005 ko02010,map02010 M00233 ko00000,ko00001,ko00002,ko02000 3.A.1.3.9 Bacteria 2I9PU@201174,4D09U@85004,COG0834@1,COG0834@2 NA|NA|NA ET Bacterial periplasmic substrate-binding proteins NIBLCNGB_00659 326426.Bbr_1132 5.3e-170 603.6 Bifidobacteriales corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 2HZ8V@201174,4CYWX@85004,COG0598@1,COG0598@2 NA|NA|NA P CorA-like Mg2+ transporter protein NIBLCNGB_00660 326426.Bbr_1133 1.6e-165 588.6 Bifidobacteriales 3.1.3.85,5.4.2.11,5.4.2.12 ko:K01834,ko:K15634,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2GJYU@201174,4CZI8@85004,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family NIBLCNGB_00661 326426.Bbr_1134 5e-232 810.1 Bifidobacteriales ko:K15257 ko00000,ko01000,ko03016 Bacteria 2HZAY@201174,4CZEU@85004,COG0742@1,COG0742@2 NA|NA|NA L ribosomal rna small subunit methyltransferase NIBLCNGB_00662 216816.GS08_05925 1e-69 269.2 Bifidobacteriales pdxH ko:K07006 ko00000 Bacteria 2IJK2@201174,4D0W8@85004,COG3576@1,COG3576@2 NA|NA|NA S Pfam:Pyridox_oxidase NIBLCNGB_00663 326426.Bbr_1136 3.1e-170 604.4 Bifidobacteriales Bacteria 2I8X5@201174,4D011@85004,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family NIBLCNGB_00664 326426.Bbr_1137 2.6e-129 468.0 Bifidobacteriales Bacteria 2GP9P@201174,4CZGH@85004,COG0778@1,COG0778@2 NA|NA|NA C Putative TM nitroreductase NIBLCNGB_00665 1437610.BREU_1546 9.4e-31 141.4 Bifidobacteriales Bacteria 2DQFC@1,2I8B6@201174,336HV@2,4D309@85004 NA|NA|NA NIBLCNGB_00666 326426.Bbr_1139 4.3e-255 886.7 Bifidobacteriales ko:K09704 ko00000 Bacteria 2HHAF@201174,4CZYN@85004,COG3538@1,COG3538@2 NA|NA|NA S Metal-independent alpha-mannosidase (GH125) NIBLCNGB_00667 326426.Bbr_1140 1.4e-234 818.5 Bifidobacteriales yihS 5.1.3.11 ko:K16213 R01445,R10810 RC00289 ko00000,ko01000 Bacteria 2GMJ7@201174,4CZNY@85004,COG2942@1,COG2942@2 NA|NA|NA G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) NIBLCNGB_00668 1437608.BBIA_1919 1.4e-137 496.1 Bifidobacteriales Bacteria 2GJHF@201174,4CZCC@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor NIBLCNGB_00669 1437610.BREU_1433 1.4e-221 775.4 Bifidobacteriales Bacteria 2GNN6@201174,4CZEH@85004,COG3934@1,COG3934@2 NA|NA|NA G Belongs to the glycosyl hydrolase 5 (cellulase A) family NIBLCNGB_00670 158787.BSCA_1686 4.5e-125 454.1 Bifidobacteriales lacG ko:K02026,ko:K17246 ko02010,map02010 M00207,M00601 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.40 Bacteria 2GMTH@201174,4D014@85004,COG0395@1,COG0395@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component NIBLCNGB_00671 158787.BSCA_1685 1.3e-123 449.5 Bifidobacteriales ko:K02025,ko:K10118,ko:K10189,ko:K15771,ko:K17245 ko02010,map02010 M00196,M00199,M00207,M00491,M00601 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.28,3.A.1.1.4,3.A.1.1.40 Bacteria 2GKJI@201174,4D0DM@85004,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component NIBLCNGB_00672 158787.BSCA_1802 1.1e-175 622.9 Bifidobacteriales srrA1 ko:K02027,ko:K17244 ko02010,map02010 M00207,M00601 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.40 Bacteria 2GJSR@201174,4D08C@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_00673 326426.Bbr_1149 0.0 1950.6 Bifidobacteriales 3.2.1.24 ko:K01191 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 GH38 Bacteria 2GM02@201174,4CYWB@85004,COG0383@1,COG0383@2 NA|NA|NA G Alpha mannosidase, middle domain NIBLCNGB_00674 216816.GS08_06690 0.0 2001.5 Bifidobacteriales 3.2.1.24 ko:K01191 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 GH38 Bacteria 2GM02@201174,4CYWB@85004,COG0383@1,COG0383@2 NA|NA|NA G Alpha mannosidase, middle domain NIBLCNGB_00675 326426.Bbr_1401 2.2e-134 485.0 Bifidobacteriales Bacteria 2I90G@201174,4D05J@85004,COG1484@1,COG1484@2 NA|NA|NA L IstB-like ATP binding protein NIBLCNGB_00676 1437609.BCAL_0101 4.2e-16 89.7 Bifidobacteriales Bacteria 2IBDV@201174,4CZS6@85004,COG4584@1,COG4584@2 NA|NA|NA L PFAM Integrase catalytic NIBLCNGB_00677 326426.Bbr_1404 2.3e-101 374.8 Bifidobacteriales Bacteria 2IBDV@201174,4CZS6@85004,COG4584@1,COG4584@2 NA|NA|NA L PFAM Integrase catalytic NIBLCNGB_00678 398513.BBNG_01193 6.1e-16 90.1 Bifidobacteriales Bacteria 2GISN@201174,4CZA9@85004,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase family NIBLCNGB_00679 326426.Bbr_1152 7e-39 166.0 Actinobacteria Bacteria 2CER0@1,2IQT8@201174,2ZM5T@2 NA|NA|NA NIBLCNGB_00680 326426.Bbr_1153 1.7e-171 608.6 Bifidobacteriales Bacteria 2ICFW@201174,4D01T@85004,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family NIBLCNGB_00681 216816.GS08_05960 1.7e-251 874.8 Bifidobacteriales Bacteria 2IEM1@201174,4CZPH@85004,COG3550@1,COG3550@2 NA|NA|NA S HipA-like C-terminal domain NIBLCNGB_00683 216816.GS08_05970 2.3e-74 284.6 Bifidobacteriales Bacteria 2ATF2@1,2IIKG@201174,31IYI@2,4D0ZG@85004 NA|NA|NA NIBLCNGB_00684 216816.GS08_05975 1.4e-183 648.7 Bifidobacteriales Bacteria 2HWAP@201174,4D0Z3@85004,COG4823@1,COG4823@2 NA|NA|NA V Abi-like protein NIBLCNGB_00685 547043.BIFPSEUDO_03924 1.8e-113 415.2 Bifidobacteriales Bacteria 2GISN@201174,4CZA9@85004,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase family NIBLCNGB_00686 326426.Bbr_0152 5e-284 983.0 Bifidobacteriales Bacteria 2IBDV@201174,4CZS6@85004,COG4584@1,COG4584@2 NA|NA|NA L PFAM Integrase catalytic NIBLCNGB_00687 326426.Bbr_0151 2.3e-147 528.1 Bifidobacteriales Bacteria 2H714@201174,4CZRM@85004,COG1484@1,COG1484@2 NA|NA|NA L IstB-like ATP binding protein NIBLCNGB_00688 547043.BIFPSEUDO_03924 2.1e-137 495.0 Bifidobacteriales Bacteria 2GISN@201174,4CZA9@85004,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase family NIBLCNGB_00689 547043.BIFPSEUDO_03925 7.2e-141 506.5 Bifidobacteriales fic GO:0008150,GO:0050789,GO:0050794,GO:0051302,GO:0065007 ko:K04095 ko00000,ko03036 Bacteria 2IN0D@201174,4D03T@85004,COG2184@1,COG2184@2 NA|NA|NA D Fic/DOC family NIBLCNGB_00690 216816.GS08_06025 9.8e-23 112.1 Bifidobacteriales Bacteria 2B0NT@1,2GRGK@201174,31T0I@2,4D1EC@85004 NA|NA|NA NIBLCNGB_00691 216816.GS08_00995 1.3e-126 459.1 Bifidobacteriales 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IEJD@201174,4CZTH@85004,COG3677@1,COG3677@2 NA|NA|NA L Transposase, Mutator family NIBLCNGB_00692 398513.BBNG_01833 3.5e-32 143.7 Bifidobacteriales Bacteria 2H9F1@201174,4D2FY@85004,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain NIBLCNGB_00693 196627.cg3058 1e-106 393.3 Corynebacteriaceae Bacteria 22K9X@1653,2GKDY@201174,COG2801@1,COG2801@2 NA|NA|NA L Transposase and inactivated derivatives NIBLCNGB_00694 1203566.HMPREF1285_01317 3.8e-29 134.0 Bacteria ko:K07483 ko00000 Bacteria COG2963@1,COG2963@2 NA|NA|NA L transposase activity NIBLCNGB_00695 1203566.HMPREF1285_01136 1.7e-154 552.0 Corynebacteriaceae ksgA 2.1.1.182,2.1.1.184 ko:K00561,ko:K02528 R10716 RC00003,RC03257 br01600,ko00000,ko01000,ko01504,ko03009 Bacteria 22JXN@1653,2H1TK@201174,COG0030@1,COG0030@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family NIBLCNGB_00696 1203567.HMPREF1286_01359 2.8e-22 110.9 Corynebacteriaceae Bacteria 22KP6@1653,2IA5I@201174,COG1002@1,COG1002@2 NA|NA|NA V Type II restriction enzyme, methylase subunits NIBLCNGB_00697 702459.BBPR_0055 2.7e-41 174.5 Bifidobacteriales ko:K07483 ko00000 Bacteria 2IQ8F@201174,4D15Y@85004,COG2963@1,COG2963@2 NA|NA|NA L Transposase NIBLCNGB_00698 1437600.JDUI01000007_gene734 3.1e-146 524.6 Bifidobacteriales tnp7109-21 Bacteria 2GKDY@201174,4CZUB@85004,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain NIBLCNGB_00699 196627.cg3058 9.3e-108 396.7 Corynebacteriaceae Bacteria 22K9X@1653,2GKDY@201174,COG2801@1,COG2801@2 NA|NA|NA L Transposase and inactivated derivatives NIBLCNGB_00700 1203566.HMPREF1285_01317 3.8e-29 134.0 Bacteria ko:K07483 ko00000 Bacteria COG2963@1,COG2963@2 NA|NA|NA L transposase activity NIBLCNGB_00701 662755.CRES_0868 5.7e-42 177.2 Corynebacteriaceae Bacteria 22Q50@1653,2HMKG@201174,COG4824@1,COG4824@2 NA|NA|NA S Bacteriophage holin family NIBLCNGB_00702 1121355.KB903375_gene1625 1.8e-59 236.1 Corynebacteriaceae 3.2.1.20,3.5.1.28 ko:K01187,ko:K01448 ko00052,ko00500,ko01100,ko01503,map00052,map00500,map01100,map01503 M00727 R00028,R00801,R00802,R04112,R06087,R06088 RC00028,RC00049,RC00064,RC00077,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 GH31 Bacteria 22NCM@1653,2HESP@201174,COG3023@1,COG3023@2 NA|NA|NA V Negative regulator of beta-lactamase expression NIBLCNGB_00703 883066.HMPREF9233_00619 5.5e-47 193.7 Actinobacteria Bacteria 2H5UT@201174,4D7T9@85005,COG1961@1,COG1961@2 NA|NA|NA L COG1961 Site-specific recombinases, DNA invertase Pin homologs NIBLCNGB_00705 77635.BISU_1293 8e-145 520.8 Bifidobacteriales Bacteria 2I8HV@201174,4D1XY@85004,COG1961@1,COG1961@2 NA|NA|NA L Recombinase NIBLCNGB_00706 191610.CATYP_00980 5.7e-225 786.9 Corynebacteriaceae Bacteria 22MQC@1653,2GMAS@201174,COG1961@1,COG1961@2 NA|NA|NA L Recombinase zinc beta ribbon domain NIBLCNGB_00707 1121360.AUAQ01000011_gene398 4.4e-91 341.3 Corynebacteriaceae Bacteria 22P79@1653,2GUZU@201174,COG5635@1,COG5635@2 NA|NA|NA T Nacht domain NIBLCNGB_00708 547043.BIFPSEUDO_03929 2.8e-28 131.0 Bacteria 2.1.1.72 ko:K07316 ko00000,ko01000,ko02048 Bacteria COG2189@1,COG2189@2 NA|NA|NA L Belongs to the N(4) N(6)-methyltransferase family NIBLCNGB_00709 547043.BIFPSEUDO_03930 2.4e-173 614.8 Bifidobacteriales Bacteria 2ICFW@201174,4D01T@85004,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family NIBLCNGB_00710 216816.GS08_05960 1.7e-251 874.8 Bifidobacteriales Bacteria 2IEM1@201174,4CZPH@85004,COG3550@1,COG3550@2 NA|NA|NA S HipA-like C-terminal domain NIBLCNGB_00712 216816.GS08_05970 2.3e-74 284.6 Bifidobacteriales Bacteria 2ATF2@1,2IIKG@201174,31IYI@2,4D0ZG@85004 NA|NA|NA NIBLCNGB_00713 326426.Bbr_1156 6e-102 376.7 Bifidobacteriales ppiA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria 2IFUE@201174,4CZSU@85004,COG0652@1,COG0652@2 NA|NA|NA G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides NIBLCNGB_00714 326426.Bbr_1157 0.0 1527.3 Bifidobacteriales relA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 Bacteria 2GJYQ@201174,4CZCW@85004,COG0317@1,COG0317@2 NA|NA|NA KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance NIBLCNGB_00715 326426.Bbr_1158 8.5e-84 316.2 Bifidobacteriales dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 ko:K01520,ko:K13038 ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100 M00053,M00120 R02100,R03269,R04231,R11896 RC00002,RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2IHYY@201174,4CZUJ@85004,COG0756@1,COG0756@2 NA|NA|NA F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA NIBLCNGB_00716 326426.Bbr_1159 1.4e-47 195.3 Bifidobacteriales Bacteria 2ATJW@1,2I80Y@201174,3361K@2,4D10Y@85004 NA|NA|NA S Domain of unknown function (DUF4193) NIBLCNGB_00717 326426.Bbr_1160 3.1e-150 538.1 Bifidobacteriales Bacteria 29W72@1,2HZB4@201174,30HS9@2,4CZFJ@85004 NA|NA|NA S Protein of unknown function (DUF3071) NIBLCNGB_00718 326426.Bbr_1161 1e-232 812.4 Bifidobacteriales Bacteria 2GISU@201174,4CZCK@85004,COG1524@1,COG1524@2 NA|NA|NA S Type I phosphodiesterase / nucleotide pyrophosphatase NIBLCNGB_00719 326426.Bbr_1162 0.0 1730.3 Bifidobacteriales gyrA GO:0005575,GO:0005622,GO:0005623,GO:0009330,GO:0032991,GO:0044424,GO:0044464 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 2GJ2Q@201174,4CYVH@85004,COG0188@1,COG0188@2 NA|NA|NA L DNA topoisomerase (ATP-hydrolyzing) NIBLCNGB_00721 326426.Bbr_1164 5.2e-43 179.9 Bifidobacteriales Bacteria 2ICPH@201174,4CZJ7@85004,COG5340@1,COG5340@2 NA|NA|NA K Psort location Cytoplasmic, score NIBLCNGB_00722 326426.Bbr_1164 1.2e-48 198.7 Bifidobacteriales Bacteria 2ICPH@201174,4CZJ7@85004,COG5340@1,COG5340@2 NA|NA|NA K Psort location Cytoplasmic, score NIBLCNGB_00723 326426.Bbr_1167 0.0 3142.1 Bifidobacteriales lhr GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 ko:K03724 ko00000,ko01000,ko03400 Bacteria 2GJG3@201174,4D01F@85004,COG1201@1,COG1201@2 NA|NA|NA L DEAD DEAH box helicase NIBLCNGB_00724 326426.Bbr_1168 7.5e-172 609.8 Bifidobacteriales rbsK 2.7.1.15 ko:K00852 ko00030,map00030 R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2I04R@201174,4CZIB@85004,COG0524@1,COG0524@2 NA|NA|NA H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway NIBLCNGB_00725 326426.Bbr_1169 4.5e-222 776.9 Bifidobacteriales Bacteria 2HWKN@201174,4CYRZ@85004,COG0738@1,COG0738@2 NA|NA|NA G Major Facilitator Superfamily NIBLCNGB_00726 326426.Bbr_1170 0.0 1540.0 Bifidobacteriales gyrB2 5.99.1.3 ko:K02470 ko00000,ko01000,ko03032,ko03400 Bacteria 2GM1E@201174,4CYXR@85004,COG0187@1,COG0187@2 NA|NA|NA L DNA topoisomerase (ATP-hydrolyzing) NIBLCNGB_00727 326426.Bbr_1171 8.2e-191 673.3 Bifidobacteriales sigA ko:K03086 ko00000,ko03021 Bacteria 2GK3Z@201174,4CZQC@85004,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth NIBLCNGB_00728 326426.Bbr_1172 3.2e-110 404.4 Bifidobacteriales Bacteria 2B5AP@1,2IF9M@201174,31Y4U@2,4D15J@85004 NA|NA|NA NIBLCNGB_00729 326426.Bbr_1173 3.6e-194 684.1 Bifidobacteriales crtE 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13787,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00365,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 2GJEK@201174,4CZQV@85004,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family NIBLCNGB_00730 326426.Bbr_1174 0.0 1312.0 Bifidobacteriales pknL 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 2GJ1J@201174,4CYTR@85004,COG0515@1,COG0515@2,COG2815@1,COG2815@2 NA|NA|NA KLT PASTA NIBLCNGB_00731 326426.Bbr_1175 6.2e-131 473.4 Bifidobacteriales plsC2 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GJ6V@201174,4CZBB@85004,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases NIBLCNGB_00732 326426.Bbr_1176 2e-118 431.8 Bifidobacteriales Bacteria 2AP35@1,2IBUY@201174,31E4N@2,4D0R7@85004 NA|NA|NA NIBLCNGB_00733 326426.Bbr_1177 1.8e-190 671.8 Bifidobacteriales trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM4G@201174,4CZKZ@85004,COG0547@1,COG0547@2 NA|NA|NA F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) NIBLCNGB_00734 326426.Bbr_1178 0.0 1841.2 Bifidobacteriales secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 2GIRT@201174,4CYX6@85004,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane NIBLCNGB_00735 326426.Bbr_1179 1.3e-111 409.1 Bifidobacteriales hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 ko:K05808 ko00000,ko03009 Bacteria 2GMYF@201174,4CZ3H@85004,COG1544@1,COG1544@2 NA|NA|NA J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase NIBLCNGB_00736 326426.Bbr_1180 3.5e-103 380.9 Bifidobacteriales recX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03565 ko00000,ko03400 Bacteria 2INKM@201174,4D0Y4@85004,COG2137@1,COG2137@2 NA|NA|NA S Modulates RecA activity NIBLCNGB_00737 326426.Bbr_1181 8.3e-197 693.0 Bifidobacteriales recA GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043142,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 ko:K03553 ko03440,map03440 M00729 ko00000,ko00001,ko00002,ko03400 Bacteria 2GJ4P@201174,4CYYY@85004,COG0468@1,COG0468@2 NA|NA|NA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage NIBLCNGB_00738 326426.Bbr_1182 1.2e-31 141.7 Bifidobacteriales Bacteria 2EFU9@1,2GQJW@201174,339KE@2,4D16T@85004 NA|NA|NA S Protein of unknown function (DUF3046) NIBLCNGB_00739 326426.Bbr_1183 1.1e-76 292.7 Bifidobacteriales Bacteria 2I2G5@201174,4D0PT@85004,COG1426@1,COG1426@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins NIBLCNGB_00740 326426.Bbr_1184 8.1e-94 349.7 Bifidobacteriales cinA 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 2IQ8T@201174,4D0CM@85004,COG1546@1,COG1546@2 NA|NA|NA S Belongs to the CinA family NIBLCNGB_00741 326426.Bbr_1185 2.1e-117 428.3 Bifidobacteriales pgsA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 Bacteria 2GK5D@201174,4CZ36@85004,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family NIBLCNGB_00742 326426.Bbr_1186 0.0 1715.3 Bifidobacteriales ftsK GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03466 ko00000,ko03036 3.A.12 Bacteria 2GK3T@201174,4CZ5T@85004,COG1674@1,COG1674@2 NA|NA|NA D FtsK SpoIIIE family protein NIBLCNGB_00743 326426.Bbr_1187 6.3e-151 540.0 Bifidobacteriales fic GO:0008150,GO:0050789,GO:0050794,GO:0051302,GO:0065007 ko:K04095 ko00000,ko03036 Bacteria 2IN0D@201174,4D03T@85004,COG2184@1,COG2184@2 NA|NA|NA D Fic/DOC family NIBLCNGB_00744 326426.Bbr_1188 3.6e-177 627.5 Bifidobacteriales miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 2GKFT@201174,4CZNS@85004,COG0324@1,COG0324@2 NA|NA|NA F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) NIBLCNGB_00745 326426.Bbr_1189 4.5e-277 959.9 Bifidobacteriales miaB 2.8.4.3 ko:K06168 R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 Bacteria 2GJEV@201174,4CZFB@85004,COG0621@1,COG0621@2 NA|NA|NA H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine NIBLCNGB_00746 326426.Bbr_1190 4.4e-149 533.9 Bifidobacteriales relA2 2.7.6.5 ko:K07816 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 2GKF8@201174,4CYXP@85004,COG2357@1,COG2357@2 NA|NA|NA S Region found in RelA / SpoT proteins NIBLCNGB_00747 326426.Bbr_1191 3.6e-166 590.9 Bifidobacteriales ydeD Bacteria 2I8X5@201174,4D0BH@85004,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family NIBLCNGB_00748 326426.Bbr_1192 4.3e-136 490.7 Bifidobacteriales ybhL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06890 ko00000 Bacteria 2I98Y@201174,4CZIJ@85004,COG0670@1,COG0670@2 NA|NA|NA S Belongs to the BI1 family NIBLCNGB_00749 326426.Bbr_1193 5.4e-81 307.0 Bifidobacteriales Bacteria 2GN80@201174,4CZRF@85004,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon NIBLCNGB_00750 326426.Bbr_1194 3.8e-119 434.1 Bifidobacteriales Bacteria 2I61X@201174,4D2U1@85004,COG1246@1,COG1246@2 NA|NA|NA E Psort location Cytoplasmic, score 8.87 NIBLCNGB_00751 326426.Bbr_1195 0.0 1791.5 Bifidobacteriales acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GJD5@201174,4CZ3T@85004,COG1048@1,COG1048@2 NA|NA|NA C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate NIBLCNGB_00752 216816.GS08_06260 0.0 1498.0 Bifidobacteriales ctpE GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 ko:K12952 ko00000,ko01000 3.A.3.23 Bacteria 2GJJC@201174,4CYS1@85004,COG0474@1,COG0474@2 NA|NA|NA P E1-E2 ATPase NIBLCNGB_00753 216816.GS08_06265 5.4e-103 380.6 Bifidobacteriales Bacteria 2AVVG@1,2INFG@201174,31MP9@2,4D12J@85004 NA|NA|NA NIBLCNGB_00754 216816.GS08_06270 2.2e-243 847.8 Bifidobacteriales trmA GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0019843,GO:0030488,GO:0030696,GO:0030697,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 ko00000,ko01000,ko03009,ko03016 Bacteria 2GIR3@201174,4CYYN@85004,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family NIBLCNGB_00755 216816.GS08_06275 7.3e-130 469.9 Bifidobacteriales Bacteria 2AVV0@1,2GJKP@201174,31MNQ@2,4CYQX@85004 NA|NA|NA S Protein of unknown function (DUF3159) NIBLCNGB_00756 216816.GS08_06280 1.1e-145 522.7 Bifidobacteriales Bacteria 28J4D@1,2I2E9@201174,30NZ9@2,4D2VD@85004 NA|NA|NA S Protein of unknown function (DUF3710) NIBLCNGB_00757 326426.Bbr_1201 2.4e-161 574.7 Bifidobacteriales exoA 3.1.11.2 ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKIS@201174,4CYVB@85004,COG0708@1,COG0708@2 NA|NA|NA L Endonuclease/Exonuclease/phosphatase family NIBLCNGB_00758 326426.Bbr_1202 0.0 1292.7 Bifidobacteriales dppD ko:K02031,ko:K02032,ko:K02034 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GIXV@201174,4D2V0@85004,COG0444@1,COG0444@2,COG1123@1,COG4172@2 NA|NA|NA EP Oligopeptide/dipeptide transporter, C-terminal region NIBLCNGB_00759 326426.Bbr_1203 1.7e-171 608.6 Bifidobacteriales dppC ko:K02031,ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2GJ9E@201174,4CYQF@85004,COG1173@1,COG1173@2 NA|NA|NA EP N-terminal TM domain of oligopeptide transport permease C NIBLCNGB_00760 216816.GS08_06300 4.4e-153 547.4 Bifidobacteriales dppB ko:K02033,ko:K13890,ko:K15581,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00348,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.11,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2GJ2C@201174,4CZSV@85004,COG0601@1,COG0601@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component NIBLCNGB_00761 326426.Bbr_1205 0.0 1089.3 Bifidobacteriales ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2GIUH@201174,4CZFK@85004,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substrate-binding protein, family 5 NIBLCNGB_00762 216816.GS08_06310 7e-179 633.3 Bifidobacteriales xerC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 2GNDP@201174,4CZCX@85004,COG4974@1,COG4974@2 NA|NA|NA D Belongs to the 'phage' integrase family. XerC subfamily NIBLCNGB_00763 216816.GS08_06315 2e-42 177.9 Bifidobacteriales Bacteria 2BGJ3@1,2IR91@201174,32AHC@2,4D17H@85004 NA|NA|NA NIBLCNGB_00764 216816.GS08_06320 1.2e-191 675.6 Bifidobacteriales tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 ko:K00210,ko:K00220,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025,M00040 R00732,R01728 RC00125 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKB4@201174,4CYV2@85004,COG0287@1,COG0287@2 NA|NA|NA E Prephenate dehydrogenase NIBLCNGB_00765 216816.GS08_06325 1.2e-185 655.6 Bifidobacteriales pheA 1.3.1.12,4.2.1.51,5.4.99.5 ko:K04517,ko:K04518,ko:K14170 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715,R01728 RC00125,RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJQ5@201174,4CZ61@85004,COG0077@1,COG0077@2 NA|NA|NA E Prephenate dehydratase NIBLCNGB_00766 216816.GS08_06330 2e-74 285.0 Bifidobacteriales Bacteria 2E9EF@1,2IKWQ@201174,333MW@2,4D10T@85004 NA|NA|NA NIBLCNGB_00767 216816.GS08_06335 0.0 1273.8 Bifidobacteriales typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 ko:K06207 ko00000 Bacteria 2GJUJ@201174,4CYX3@85004,COG1217@1,COG1217@2 NA|NA|NA T Elongation factor G C-terminus NIBLCNGB_00768 216816.GS08_06355 1.2e-244 852.0 Bifidobacteriales naiP GO:0005575,GO:0016020,GO:0016021,GO:0031224,GO:0044425 ko:K08369 ko00000,ko02000 2.A.1 Bacteria 2HC9X@201174,4D2V1@85004,COG0477@1,COG0477@2 NA|NA|NA U Sugar (and other) transporter NIBLCNGB_00769 216816.GS08_06360 2.5e-220 771.2 Bifidobacteriales iscS1 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 2GKUT@201174,4CZVW@85004,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class-V NIBLCNGB_00770 216816.GS08_06365 2.3e-162 578.2 Bifidobacteriales nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0030312,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 1.4.3.16,2.4.2.19 ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481,R03348 RC00006,RC02566,RC02877 ko00000,ko00001,ko00002,ko01000 Bacteria 2GV9P@201174,4CZWA@85004,COG0157@1,COG0157@2 NA|NA|NA H Quinolinate phosphoribosyl transferase, N-terminal domain NIBLCNGB_00771 216816.GS08_06370 2.7e-299 1033.9 Bifidobacteriales nadB GO:0008150,GO:0040007 1.3.5.4,1.4.3.16,2.4.2.19 ko:K00244,ko:K00278,ko:K00767 ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00115,M00150,M00173 R00357,R00481,R02164,R03348 RC00006,RC00045,RC02566,RC02877 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1595 Bacteria 2I2IJ@201174,4D01P@85004,COG0029@1,COG0029@2 NA|NA|NA H Catalyzes the oxidation of L-aspartate to iminoaspartate NIBLCNGB_00772 216816.GS08_06375 2e-249 867.8 Bifidobacteriales nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM59@201174,4D0AI@85004,COG0379@1,COG0379@2 NA|NA|NA H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate NIBLCNGB_00773 216816.GS08_06380 1.6e-154 552.0 Bifidobacteriales nrtR 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 2GNMT@201174,4CZNZ@85004,COG1051@1,COG1051@2 NA|NA|NA F NUDIX hydrolase NIBLCNGB_00774 216816.GS08_06385 2e-116 425.2 Bifidobacteriales scpB ko:K06024 ko00000,ko03036 Bacteria 2GISY@201174,4D0QW@85004,COG1386@1,COG1386@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves NIBLCNGB_00775 216816.GS08_06390 2e-153 548.5 Bifidobacteriales scpA ko:K05896 ko00000,ko03036 Bacteria 2GN1U@201174,4CYRV@85004,COG1354@1,COG1354@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves NIBLCNGB_00776 216816.GS08_06395 1.4e-149 535.8 Bifidobacteriales soj GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 ko:K03496 ko00000,ko03036,ko04812 Bacteria 2GJX3@201174,4CYV4@85004,COG1192@1,COG1192@2 NA|NA|NA D CobQ CobB MinD ParA nucleotide binding domain protein NIBLCNGB_00777 326426.Bbr_1226 1.2e-145 522.7 Bifidobacteriales xerD GO:0008150,GO:0040007 ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 2GNDP@201174,4CZ69@85004,COG4974@1,COG4974@2 NA|NA|NA D recombinase XerD NIBLCNGB_00778 326426.Bbr_1227 6.2e-197 693.3 Bifidobacteriales glxK 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 R08572 RC00002,RC00428 ko00000,ko00001,ko01000 Bacteria 2GKHX@201174,4CZRH@85004,COG1929@1,COG1929@2 NA|NA|NA G Belongs to the glycerate kinase type-1 family NIBLCNGB_00779 326426.Bbr_1228 2.1e-61 241.5 Bifidobacteriales rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHTN@201174,4D0QF@85004,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit NIBLCNGB_00780 326426.Bbr_1229 6.2e-25 119.4 Bifidobacteriales rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02916 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2HZRM@201174,4D1EV@85004,COG0291@1,COG0291@2 NA|NA|NA J Ribosomal protein L35 NIBLCNGB_00781 326426.Bbr_1230 1.7e-113 415.6 Bifidobacteriales infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 2GJGT@201174,4CZA3@85004,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins NIBLCNGB_00782 326426.Bbr_1231 1.6e-10 71.6 Bifidobacteriales Bacteria 2I372@201174,4D060@85004,COG4262@1,COG4262@2 NA|NA|NA S Spermine/spermidine synthase domain NIBLCNGB_00783 326426.Bbr_1232 1e-133 482.6 Bifidobacteriales 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 R00619 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2HQZZ@201174,4CZBY@85004,COG1564@1,COG1564@2 NA|NA|NA H Thiamin pyrophosphokinase, vitamin B1 binding domain NIBLCNGB_00784 216816.GS08_06425 1.3e-196 692.2 Bifidobacteriales gap GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009986,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0022610,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044464,GO:0044650,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:0140030,GO:0140032,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iJR904.b1416,iJR904.b1417 Bacteria 2GJK4@201174,4CZ97@85004,COG0057@1,COG0057@2 NA|NA|NA G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family NIBLCNGB_00785 326426.Bbr_1234 1.2e-88 332.4 Bifidobacteriales ybaK GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K03976 ko00000,ko01000,ko03016 Bacteria 2IHS8@201174,4CZFI@85004,COG2606@1,COG2606@2 NA|NA|NA J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily NIBLCNGB_00786 326426.Bbr_1235 7.5e-183 646.4 Bifidobacteriales ispH 1.17.7.4,2.7.4.25 ko:K00945,ko:K02945,ko:K03527 ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010 M00052,M00096,M00178 R00158,R00512,R01665,R05884,R08210 RC00002,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 iIT341.HP0400,iLJ478.TM1444 Bacteria 2GIZ7@201174,4CZ8B@85004,COG0761@1,COG0761@2 NA|NA|NA IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis NIBLCNGB_00787 326426.Bbr_1236 1.6e-190 671.8 Bifidobacteriales galM 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ0H@201174,4CYWN@85004,COG2017@1,COG2017@2 NA|NA|NA G Aldose 1-epimerase NIBLCNGB_00788 326426.Bbr_1237 3.8e-184 650.6 Bifidobacteriales galM 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ0H@201174,4CYWN@85004,COG2017@1,COG2017@2 NA|NA|NA G Aldose 1-epimerase NIBLCNGB_00789 326426.Bbr_1238 5.6e-52 209.9 Bifidobacteriales Bacteria 29M53@1,2GTWX@201174,3082I@2,4D1EJ@85004 NA|NA|NA NIBLCNGB_00790 326426.Bbr_1239 4e-136 490.7 Bifidobacteriales sigH ko:K03088 ko00000,ko03021 Bacteria 2GJ02@201174,4CZ09@85004,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily NIBLCNGB_00791 326426.Bbr_1240 1.8e-292 1011.1 Bifidobacteriales murE 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 Bacteria 2GIS2@201174,4CZAF@85004,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan NIBLCNGB_00792 326426.Bbr_1241 6.9e-192 676.4 Bifidobacteriales Bacteria 2GJUD@201174,4CZT9@85004,COG2348@1,COG2348@2 NA|NA|NA V Acetyltransferase (GNAT) domain NIBLCNGB_00793 326426.Bbr_1242 2.6e-20 104.4 Bifidobacteriales Bacteria 2GJUD@201174,4CZT9@85004,COG2348@1,COG2348@2 NA|NA|NA V Acetyltransferase (GNAT) domain NIBLCNGB_00794 326426.Bbr_1242 3.1e-41 174.1 Bifidobacteriales Bacteria 2GJUD@201174,4CZT9@85004,COG2348@1,COG2348@2 NA|NA|NA V Acetyltransferase (GNAT) domain NIBLCNGB_00795 326426.Bbr_1243 0.0 1889.0 Bifidobacteriales smc GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03529,ko:K19171 ko00000,ko02048,ko03036 Bacteria 2GK93@201174,4CZ8Q@85004,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning NIBLCNGB_00796 326426.Bbr_1244 3e-298 1030.4 Bifidobacteriales folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2447c Bacteria 2GJP2@201174,4CZG9@85004,COG0285@1,COG0285@2 NA|NA|NA H Mur ligase middle domain NIBLCNGB_00797 326426.Bbr_1245 0.0 1081.2 Bifidobacteriales pepP 3.4.11.9 ko:K01262 ko00000,ko01000,ko01002 Bacteria 2GM7D@201174,4CZIA@85004,COG0006@1,COG0006@2 NA|NA|NA E Aminopeptidase P, N-terminal domain NIBLCNGB_00798 326426.Bbr_1246 3.1e-95 354.4 Bifidobacteriales 3.6.1.55 ko:K03574,ko:K06287 ko00000,ko01000,ko03400 Bacteria 2IKKB@201174,4CZS4@85004,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain NIBLCNGB_00799 326426.Bbr_1247 6.5e-248 862.8 Bifidobacteriales nagA 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 R02059 RC00166,RC00300 ko00000,ko00001,ko01000 Bacteria 2GK1E@201174,4CZKB@85004,COG1820@1,COG1820@2 NA|NA|NA G Amidohydrolase family NIBLCNGB_00800 326426.Bbr_1248 1.4e-150 538.9 Bifidobacteriales nagB 3.1.1.31,3.5.99.6 ko:K01057,ko:K02564 ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R00765,R02035 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK7F@201174,4CYYE@85004,COG0363@1,COG0363@2 NA|NA|NA G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion NIBLCNGB_00801 326426.Bbr_1249 6.9e-209 733.0 Bifidobacteriales Bacteria 2GKMZ@201174,4CZUF@85004,COG1940@1,COG1940@2 NA|NA|NA GK ROK family NIBLCNGB_00802 326426.Bbr_1250 2.2e-165 588.2 Bifidobacteriales 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GZ27@201174,4CZII@85004,COG1940@1,COG1940@2 NA|NA|NA GK ROK family NIBLCNGB_00803 326426.Bbr_1251 8.7e-226 789.3 Bifidobacteriales Bacteria 2GJ2S@201174,4CYV9@85004,COG1940@1,COG1940@2 NA|NA|NA GK ROK family NIBLCNGB_00804 326426.Bbr_1252 2e-166 591.7 Bifidobacteriales 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2HZB3@201174,4CZFC@85004,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase NIBLCNGB_00805 326426.Bbr_1254 3e-47 195.3 Bifidobacteriales dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K07560 ko00000,ko01000,ko03016 Bacteria 2IKVR@201174,4D0VE@85004,COG1490@1,COG1490@2 NA|NA|NA J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality NIBLCNGB_00806 398513.BBNG_00476 7e-15 87.0 Bifidobacteriales Bacteria 2B3SJ@1,2GX7W@201174,31WG6@2,4D1T0@85004 NA|NA|NA NIBLCNGB_00807 326426.Bbr_1255 7.3e-173 613.2 Bifidobacteriales ftsQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 6.3.2.4 ko:K01921,ko:K03589,ko:K06438 ko00473,ko00550,ko01100,ko01502,ko04112,map00473,map00550,map01100,map01502,map04112 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011,ko03036 Bacteria 2H4A4@201174,4D04A@85004,COG1589@1,COG1589@2 NA|NA|NA D Cell division protein FtsQ NIBLCNGB_00808 326426.Bbr_1256 4.9e-282 976.5 Bifidobacteriales murC GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2I2E7@201174,4CZ3B@85004,COG0773@1,COG0773@2 NA|NA|NA M Belongs to the MurCDEF family NIBLCNGB_00809 326426.Bbr_1257 5.9e-219 766.5 Bifidobacteriales murG GO:0008150,GO:0040007 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 GT28 iLJ478.TM0232 Bacteria 2GJEM@201174,4CYQS@85004,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) NIBLCNGB_00810 326426.Bbr_1258 9.7e-225 785.8 Bifidobacteriales ftsW GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 2.4.1.227 ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 2.A.103.1 GT28 Bacteria 2GKXP@201174,4CYPZ@85004,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family NIBLCNGB_00811 326426.Bbr_1259 6.6e-273 946.0 Bifidobacteriales murD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iNJ661.Rv2155c Bacteria 2GJZA@201174,4CZKI@85004,COG0771@1,COG0771@2 NA|NA|NA M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) NIBLCNGB_00812 326426.Bbr_1260 1.7e-204 718.4 Bifidobacteriales mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Bacteria 2GNEH@201174,4CYRX@85004,COG0472@1,COG0472@2 NA|NA|NA M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan NIBLCNGB_00813 326426.Bbr_1261 9.7e-240 835.9 Bifidobacteriales murF 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2GK0Y@201174,4CZ7U@85004,COG0770@1,COG0770@2 NA|NA|NA M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein NIBLCNGB_00814 326426.Bbr_1262 2.6e-155 554.7 Bifidobacteriales yqeC 6.3.2.10,6.3.2.13 ko:K01928,ko:K15792 ko00300,ko00550,map00300,map00550 R02788,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2GMZF@201174,4CYWT@85004,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan NIBLCNGB_00815 326426.Bbr_1263 0.0 1146.3 Bifidobacteriales ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 2GKHH@201174,4CYS8@85004,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding protein, transpeptidase domain protein NIBLCNGB_00816 326426.Bbr_1264 4e-67 260.8 Bifidobacteriales ftsL ko:K05589,ko:K12065 ko00000,ko02044,ko03036 3.A.7.11.1 Bacteria 2IKUA@201174,4D109@85004,COG2919@1,COG2919@2 NA|NA|NA D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic NIBLCNGB_00817 326426.Bbr_1265 1.8e-190 671.8 Bifidobacteriales rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 2GJGK@201174,4CYRM@85004,COG0275@1,COG0275@2 NA|NA|NA J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA NIBLCNGB_00818 326426.Bbr_1266 1.3e-93 349.0 Bifidobacteriales mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 ko:K03925 ko00000 Bacteria 2IHUB@201174,4D0P1@85004,COG2001@1,COG2001@2 NA|NA|NA K Belongs to the MraZ family NIBLCNGB_00819 326426.Bbr_1267 0.0 1474.1 Bifidobacteriales Bacteria 2GK30@201174,4CYUF@85004,COG3973@1,COG3973@2 NA|NA|NA L DNA helicase NIBLCNGB_00820 326426.Bbr_1268 7.5e-230 802.7 Bifidobacteriales serA GO:0003674,GO:0003824,GO:0004617,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008219,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0012501,GO:0016053,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047545,GO:0055114,GO:0070905,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 iYL1228.KPN_03348 Bacteria 2GJGA@201174,4CYPT@85004,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NIBLCNGB_00821 326426.Bbr_1269 8.4e-78 296.2 Bifidobacteriales nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K07738 ko00000,ko03000 Bacteria 2IHU9@201174,4D0P7@85004,COG1327@1,COG1327@2 NA|NA|NA K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes NIBLCNGB_00822 326426.Bbr_1270 4.3e-46 190.7 Bifidobacteriales Bacteria 2HVH4@201174,4D1G8@85004,COG1388@1,COG1388@2 NA|NA|NA M Lysin motif NIBLCNGB_00823 326426.Bbr_1271 8.4e-128 463.0 Bifidobacteriales lexA 3.4.21.88 ko:K01356 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 2GMBN@201174,4CZ26@85004,COG1974@1,COG1974@2 NA|NA|NA K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair NIBLCNGB_00824 326426.Bbr_1272 2.4e-162 578.2 Bifidobacteriales czcD ko:K16264 ko00000,ko02000 2.A.4.1 Bacteria 2GMRZ@201174,4CZAB@85004,COG1230@1,COG1230@2 NA|NA|NA P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family NIBLCNGB_00825 326426.Bbr_1273 1.7e-176 625.2 Bifidobacteriales ldh 1.1.1.27,1.1.1.37 ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R00703,R01000,R03104,R07136 RC00031,RC00044 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GN5S@201174,4CYWK@85004,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily. LDH family NIBLCNGB_00826 326426.Bbr_1274 6.9e-273 946.0 Bifidobacteriales hflX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 ko:K03665 ko00000,ko03009 Bacteria 2GK55@201174,4CZCB@85004,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis NIBLCNGB_00827 326426.Bbr_1275 3.4e-123 447.6 Bifidobacteriales rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 2IFG7@201174,4CZP1@85004,COG2813@1,COG2813@2 NA|NA|NA J Ribosomal protein L11 methyltransferase (PrmA) NIBLCNGB_00828 326426.Bbr_1276 0.0 2701.8 Bifidobacteriales hrpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K03578 ko00000,ko01000 Bacteria 2GIWX@201174,4CZ3C@85004,COG1643@1,COG1643@2 NA|NA|NA L Helicase associated domain (HA2) Add an annotation NIBLCNGB_00829 326426.Bbr_1277 2.3e-218 764.6 Bifidobacteriales Bacteria 2GK8C@201174,4CZH1@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily NIBLCNGB_00830 326426.Bbr_1278 2.1e-265 921.0 Bifidobacteriales glnA2 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 2GJ2I@201174,4CZ0G@85004,COG0174@1,COG0174@2 NA|NA|NA E glutamine synthetase NIBLCNGB_00831 326426.Bbr_1279 1.8e-278 964.5 Bifidobacteriales Bacteria 2GKEK@201174,4CZIY@85004,COG4320@1,COG4320@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2252) NIBLCNGB_00832 326426.Bbr_1280 1.3e-131 475.7 Bifidobacteriales hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16,5.3.1.24 ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 M00023,M00026 R03509,R04640 RC00945 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ4V@201174,4CZEA@85004,COG0106@1,COG0106@2 NA|NA|NA E Histidine biosynthesis protein NIBLCNGB_00833 326426.Bbr_1281 1.4e-121 442.2 Bifidobacteriales hisH GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIYS@201174,4CZGA@85004,COG0118@1,COG0118@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR NIBLCNGB_00834 326426.Bbr_1282 1.5e-98 365.9 Bifidobacteriales Bacteria 2EKCN@1,2GNIC@201174,33E2Y@2,4D0B5@85004 NA|NA|NA NIBLCNGB_00835 326426.Bbr_1283 4.6e-111 407.1 Bifidobacteriales hisB GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,2.6.1.9,3.1.3.15,4.2.1.19 ko:K00013,ko:K00817,ko:K01089,ko:K01693 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R01158,R01163,R03012,R03013,R03243,R03457 RC00006,RC00017,RC00099,RC00242,RC00463,RC00888,RC00932 ko00000,ko00001,ko00002,ko01000,ko01007 iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iLJ478.TM1039,iSB619.SA_RS14130,iUMNK88_1353.UMNK88_2570 Bacteria 2GKMD@201174,4CZDD@85004,COG0131@1,COG0131@2 NA|NA|NA E Imidazoleglycerol-phosphate dehydratase NIBLCNGB_00836 326426.Bbr_1284 1.8e-220 771.5 Bifidobacteriales hisC GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GJ9W@201174,4CZDT@85004,COG0079@1,COG0079@2 NA|NA|NA E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily NIBLCNGB_00837 326426.Bbr_1285 1.7e-254 884.8 Bifidobacteriales hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 ko:K00013,ko:K15509 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1599 Bacteria 2GKKA@201174,4CZ3E@85004,COG0141@1,COG0141@2 NA|NA|NA E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine NIBLCNGB_00838 326426.Bbr_1286 1.1e-53 215.7 Bifidobacteriales acyP GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036 Bacteria 2HZRI@201174,4D1EM@85004,COG1254@1,COG1254@2 NA|NA|NA C Acylphosphatase NIBLCNGB_00839 326426.Bbr_1287 7.7e-157 559.7 Bifidobacteriales yvgN 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 2GJQ7@201174,4CZ1F@85004,COG0656@1,COG0656@2 NA|NA|NA S Aldo/keto reductase family NIBLCNGB_00840 326426.Bbr_1288 0.0 1590.1 Bifidobacteriales 2.4.1.230,3.2.1.51 ko:K10231,ko:K15923 ko00511,map00511 ko00000,ko00001,ko01000 GH65,GH95 Bacteria 2GJXJ@201174,4CZZK@85004,COG1554@1,COG1554@2 NA|NA|NA G Glycosyl hydrolase family 65, N-terminal domain NIBLCNGB_00841 216816.GS08_01715 2.6e-285 987.3 Bifidobacteriales fucA 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria 2I650@201174,4CZPN@85004,COG3669@1,COG3669@2 NA|NA|NA G Alpha-L-fucosidase NIBLCNGB_00842 216816.GS08_01710 3.2e-77 294.3 Bifidobacteriales fucU GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016853,GO:0016854,GO:0016857,GO:0030246,GO:0036094,GO:0042806,GO:0044424,GO:0044464,GO:0048029 5.1.3.29 ko:K02431 R10764 RC00563 ko00000,ko01000 Bacteria 2INSY@201174,4D122@85004,COG4154@1,COG4154@2 NA|NA|NA G RbsD / FucU transport protein family NIBLCNGB_00843 216816.GS08_01705 8.3e-165 586.3 Bifidobacteriales dapA 4.1.2.28,4.3.3.7 ko:K01714,ko:K22397 ko00040,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00040,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R01782,R10147 RC00307,RC00572,RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJDB@201174,4D04B@85004,COG0329@1,COG0329@2 NA|NA|NA EM Dihydrodipicolinate synthetase family NIBLCNGB_00844 547043.BIFPSEUDO_03221 1.1e-152 545.8 Bifidobacteriales ko:K07046 ko00051,ko01120,map00051,map01120 R10689 RC00537 ko00000,ko00001,ko01000 Bacteria 2HRH9@201174,4CZX0@85004,COG3618@1,COG3618@2 NA|NA|NA S Amidohydrolase NIBLCNGB_00845 326426.Bbr_1291 2.6e-146 524.6 Bifidobacteriales Bacteria 2GJGM@201174,4CZXI@85004,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain NIBLCNGB_00846 547043.BIFPSEUDO_03223 2.9e-165 587.8 Bifidobacteriales 4.2.1.68 ko:K18334 ko00051,ko01120,map00051,map01120 R03688 RC00543 ko00000,ko00001,ko01000 Bacteria 2GKSK@201174,4D0EI@85004,COG4948@1,COG4948@2 NA|NA|NA M Enolase C-terminal domain-like NIBLCNGB_00847 1121439.dsat_2904 9.2e-10 70.5 Proteobacteria Bacteria 1NMSQ@1224,2AZ0G@1,31R6J@2 NA|NA|NA NIBLCNGB_00848 326426.Bbr_1293 0.0 1315.8 Bifidobacteriales 4.2.1.53 ko:K10254 ko00000,ko01000 Bacteria 2GKZ8@201174,4CYZK@85004,COG4716@1,COG4716@2 NA|NA|NA S MCRA family NIBLCNGB_00849 326426.Bbr_1294 1.8e-167 595.1 Bifidobacteriales dkgA GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008106,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 iECH74115_1262.ECH74115_4323,iECSP_1301.ECSP_3988 Bacteria 2GJQ7@201174,4CZXR@85004,COG0656@1,COG0656@2 NA|NA|NA C Aldo/keto reductase family NIBLCNGB_00850 326426.Bbr_1295 5.7e-39 166.4 Bifidobacteriales yneG Bacteria 2DMJC@1,2IHZV@201174,32RYJ@2,4D0UY@85004 NA|NA|NA S Domain of unknown function (DUF4186) NIBLCNGB_00851 326426.Bbr_1296 0.0 2380.5 Bifidobacteriales dnaE 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJ1P@201174,4CZKT@85004,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase III alpha subunit NIBLCNGB_00852 326426.Bbr_1297 1.7e-201 708.4 Bifidobacteriales ko:K07012 ko00000,ko01000,ko02048 Bacteria 2IAIA@201174,4CYRS@85004,COG2378@1,COG2378@2 NA|NA|NA K WYL domain NIBLCNGB_00853 326426.Bbr_1298 5.8e-177 626.7 Bifidobacteriales rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 2GIY1@201174,4CYYR@85004,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil NIBLCNGB_00854 326426.Bbr_1299 5.4e-90 337.0 Bifidobacteriales lspA 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 2GKRX@201174,4D0WR@85004,COG0597@1,COG0597@2 NA|NA|NA MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins NIBLCNGB_00855 326426.Bbr_1300 5.3e-22 112.5 Bifidobacteriales tccB2 ko:K02004,ko:K06218,ko:K16552 M00258 ko00000,ko00002,ko02000,ko02048 1.B.18.1,3.A.1 Bacteria 2I2G9@201174,4CZ5W@85004,COG1566@1,COG1566@2 NA|NA|NA V DivIVA protein NIBLCNGB_00856 326426.Bbr_1301 4.9e-45 186.8 Bifidobacteriales yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02221 ko00000,ko02044 Bacteria 2GQI1@201174,4D17B@85004,COG0762@1,COG0762@2 NA|NA|NA S YGGT family NIBLCNGB_00857 326426.Bbr_1302 5.9e-69 266.9 Bifidobacteriales sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0051301,GO:0071840,GO:0090529 ko:K09772 ko00000,ko03036 Bacteria 2GNVH@201174,4D0RJ@85004,COG1799@1,COG1799@2 NA|NA|NA D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA NIBLCNGB_00858 326426.Bbr_1303 1.2e-211 742.3 Bifidobacteriales ftsZ GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Bacteria 2GJWC@201174,4CZ10@85004,COG0206@1,COG0206@2 NA|NA|NA D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity NIBLCNGB_00859 326426.Bbr_1304 5.7e-249 866.3 Bifidobacteriales dus GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090 Bacteria 2GJ8I@201174,4CZFD@85004,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines NIBLCNGB_00860 326426.Bbr_1305 6.7e-297 1025.8 Bifidobacteriales glyQS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iSB619.SA_RS07880 Bacteria 2GIT3@201174,4CYZU@85004,COG0423@1,COG0423@2 NA|NA|NA J Catalyzes the attachment of glycine to tRNA(Gly) NIBLCNGB_00861 216816.GS08_07010 8.8e-157 559.7 Bifidobacteriales thiM 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2IC73@201174,4CZU8@85004,COG2145@1,COG2145@2 NA|NA|NA H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) NIBLCNGB_00862 326426.Bbr_1312 0.0 1804.3 Bifidobacteriales thiC GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 ko:K00788,ko:K03147,ko:K14153 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R03472,R04509,R10712 RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 iYO844.BSU08790,iYO844.BSU38290 Bacteria 2GJ3Y@201174,4D2W5@85004,COG0352@1,COG0352@2,COG0422@1,COG0422@2 NA|NA|NA H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction NIBLCNGB_00863 326426.Bbr_1313 1.7e-229 801.6 Bifidobacteriales ko:K13525,ko:K13527 ko03050,ko04141,ko05134,map03050,map04141,map05134 M00342,M00400,M00403 ko00000,ko00001,ko00002,ko03019,ko03051,ko04131,ko04147 3.A.16.1 Bacteria 2I5C1@201174,4D0DP@85004,COG1222@1,COG1222@2 NA|NA|NA O AAA domain (Cdc48 subfamily) NIBLCNGB_00864 326426.Bbr_1314 4.6e-146 523.9 Bifidobacteriales thiD 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 ko:K00941,ko:K03147,ko:K14153 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R03472,R04509,R10712 RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2909 Bacteria 2GKZM@201174,4CYQA@85004,COG0351@1,COG0351@2 NA|NA|NA H Phosphomethylpyrimidine kinase NIBLCNGB_00865 216816.GS08_07030 9.5e-62 242.7 Bifidobacteriales GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 Bacteria 2IQ7E@201174,4D14E@85004,COG0011@1,COG0011@2 NA|NA|NA S Thiamine-binding protein NIBLCNGB_00866 216816.GS08_07035 7.1e-248 862.8 Bifidobacteriales ydjK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K08369 ko00000,ko02000 2.A.1 Bacteria 2I32P@201174,4D2WZ@85004,COG2271@1,COG2271@2 NA|NA|NA G Sugar (and other) transporter NIBLCNGB_00867 326426.Bbr_1317 4.4e-213 747.3 Bifidobacteriales 2.7.13.3 ko:K07675,ko:K20263 ko02020,ko02024,map02020,map02024 M00473,M00818 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2I370@201174,4D0JE@85004,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase NIBLCNGB_00868 326426.Bbr_1318 6.1e-123 446.8 Bifidobacteriales Bacteria 2HRPE@201174,4D098@85004,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon NIBLCNGB_00869 326426.Bbr_1319 5e-190 670.2 Bifidobacteriales Bacteria 2CK5B@1,2HU05@201174,2ZYDK@2,4D0JT@85004 NA|NA|NA NIBLCNGB_00870 326426.Bbr_1320 1.3e-257 895.2 Bifidobacteriales ko:K13963 ko05146,map05146 ko00000,ko00001 Bacteria 2GJ5T@201174,4D0C1@85004,COG4826@1,COG4826@2 NA|NA|NA O SERine Proteinase INhibitors NIBLCNGB_00871 216816.GS08_07060 1.8e-195 688.3 Bifidobacteriales ko:K02529 ko00000,ko03000 Bacteria 2GJY9@201174,4CYU5@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor NIBLCNGB_00872 401473.BDP_1602 6.2e-241 839.7 Bifidobacteriales lacY ko:K02532,ko:K05820,ko:K08167,ko:K08218,ko:K08369 ko01501,map01501 M00628,M00713,M00714 ko00000,ko00001,ko00002,ko01504,ko02000 2.A.1,2.A.1.25,2.A.1.27,2.A.1.3,2.A.1.5 Bacteria 2GJRD@201174,4CYTK@85004,COG2807@1,COG2807@2 NA|NA|NA P LacY proton/sugar symporter NIBLCNGB_00873 326426.Bbr_1324 3e-303 1047.0 Bifidobacteriales cscA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 GH32 iE2348C_1286.E2348C_2556,iEC55989_1330.EC55989_2656,iECIAI1_1343.ECIAI1_2428 Bacteria 2GJ9T@201174,4CZ8W@85004,COG1621@1,COG1621@2 NA|NA|NA G Belongs to the glycosyl hydrolase 32 family NIBLCNGB_00874 326426.Bbr_1325 3.2e-141 507.7 Bifidobacteriales ppgK 2.7.1.2,2.7.1.63 ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786,R02187,R02189 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJA0@201174,4CYR1@85004,COG1940@1,COG1940@2 NA|NA|NA GK ROK family NIBLCNGB_00875 326426.Bbr_1326 3.6e-148 530.8 Bifidobacteriales Bacteria 2IAH8@201174,4D04W@85004,COG0778@1,COG0778@2 NA|NA|NA C Putative TM nitroreductase NIBLCNGB_00876 326426.Bbr_1327 1.4e-197 695.3 Bifidobacteriales Bacteria 2GMQQ@201174,4CZRJ@85004,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase, group 2 family protein NIBLCNGB_00877 326426.Bbr_1328 5.3e-92 344.0 Bifidobacteriales ribU GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 Bacteria 2IAX0@201174,4CZQD@85004,COG3601@1,COG3601@2 NA|NA|NA U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins NIBLCNGB_00878 326426.Bbr_1329 0.0 1437.9 Bifidobacteriales ecfA ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2I2G4@201174,4CZJE@85004,COG0619@1,COG0619@2,COG1129@1,COG1129@2 NA|NA|NA GP ABC transporter, ATP-binding protein NIBLCNGB_00879 326426.Bbr_1330 3.1e-47 194.1 Bifidobacteriales yhbY GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 ko:K07574 ko00000,ko03009 Bacteria 2IKSS@201174,4D10K@85004,COG1534@1,COG1534@2 NA|NA|NA J CRS1_YhbY NIBLCNGB_00880 326426.Bbr_1331 1.6e-53 215.3 Bifidobacteriales yvlD ko:K08972 ko00000 Bacteria 2HZND@201174,4D117@85004,COG1950@1,COG1950@2 NA|NA|NA S Mycobacterial 4 TMS phage holin, superfamily IV NIBLCNGB_00881 1437609.BCAL_0492 5.7e-54 216.9 Bifidobacteriales Bacteria 29SSD@1,2IJ1J@201174,30DYB@2,4D0SG@85004 NA|NA|NA NIBLCNGB_00882 326426.Bbr_1333 2.2e-187 661.4 Bifidobacteriales ghrA Bacteria 2GP09@201174,4CZUN@85004,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NIBLCNGB_00883 326426.Bbr_1334 1.9e-251 874.8 Bifidobacteriales ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 2GIZX@201174,4CZ0R@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily NIBLCNGB_00884 216816.GS08_07475 2.1e-34 152.1 Bifidobacteriales mtrB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 2.7.13.3 ko:K02484,ko:K07653,ko:K07654 ko02020,map02020 M00460,M00461 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2GJ2D@201174,4D03C@85004,COG5002@1,COG5002@2 NA|NA|NA T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain NIBLCNGB_00885 216816.GS08_07480 2.2e-09 67.4 Bifidobacteriales Bacteria 2GJE6@201174,4D2SY@85004,COG0745@1,COG0745@2 NA|NA|NA KT Transcriptional regulatory protein, C terminal NIBLCNGB_00886 326426.Bbr_1337 7.5e-250 869.4 Bifidobacteriales rarA ko:K07478 ko00000 Bacteria 2GKDP@201174,4CZ2K@85004,COG2256@1,COG2256@2 NA|NA|NA L Recombination factor protein RarA NIBLCNGB_00887 326426.Bbr_1338 0.0 1702.6 Bifidobacteriales helY ko:K03727 ko00000,ko01000 Bacteria 2GJSV@201174,4CZVX@85004,COG4581@1,COG4581@2 NA|NA|NA L DEAD DEAH box helicase NIBLCNGB_00888 326426.Bbr_1339 4e-198 697.2 Bifidobacteriales 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2GKRN@201174,4CZZU@85004,COG2326@1,COG2326@2 NA|NA|NA S Polyphosphate kinase 2 (PPK2) NIBLCNGB_00890 326426.Bbr_1340 3.2e-286 990.3 Bifidobacteriales ydfD ko:K03710,ko:K18907 M00700,M00702 ko00000,ko00002,ko01504,ko03000 Bacteria 2GITW@201174,4CZGJ@85004,COG1167@1,COG1167@2 NA|NA|NA EK Alanine-glyoxylate amino-transferase NIBLCNGB_00891 326426.Bbr_1341 5.1e-111 407.1 Bifidobacteriales argO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 ko:K06895 ko00000,ko02000 2.A.75.1 iPC815.YPO0918 Bacteria 2HZBK@201174,4CZJP@85004,COG1279@1,COG1279@2 NA|NA|NA S LysE type translocator NIBLCNGB_00892 326426.Bbr_1342 4.1e-289 1000.0 Bifidobacteriales phoN Bacteria 2I4ZG@201174,4CZ80@85004,COG0671@1,COG0671@2 NA|NA|NA I PAP2 superfamily NIBLCNGB_00893 326426.Bbr_1343 1.7e-204 718.4 Bifidobacteriales gluD ko:K02029,ko:K10007 ko02010,map02010 M00233,M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.9 Bacteria 2GNBH@201174,4CZB4@85004,COG0765@1,COG0765@2 NA|NA|NA E Binding-protein-dependent transport system inner membrane component NIBLCNGB_00894 326426.Bbr_1344 3.4e-110 404.4 Bifidobacteriales gluC GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K10006,ko:K10040 ko02010,map02010 M00228,M00233 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.9 Bacteria 2GNUR@201174,4CZ5M@85004,COG0765@1,COG0765@2 NA|NA|NA E Binding-protein-dependent transport system inner membrane component NIBLCNGB_00895 326426.Bbr_1345 2.2e-145 521.5 Bifidobacteriales gluB ko:K10005 ko02010,map02010 M00233 ko00000,ko00001,ko00002,ko02000 3.A.1.3.9 Bacteria 2GJH8@201174,4CZA4@85004,COG0834@1,COG0834@2 NA|NA|NA ET Belongs to the bacterial solute-binding protein 3 family NIBLCNGB_00896 326426.Bbr_1346 1.2e-152 545.8 Bifidobacteriales gluA 3.6.3.21 ko:K02028,ko:K10008 ko02010,map02010 M00233,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.9 Bacteria 2GIZW@201174,4CYXE@85004,COG1126@1,COG1126@2 NA|NA|NA E ATP-binding protein of ABC transporter for glutamate K02028 NIBLCNGB_00897 326426.Bbr_1347 1.2e-100 372.5 Bifidobacteriales ko:K03976,ko:K19055 ko00000,ko01000,ko03016 Bacteria 2GKUX@201174,4D0MH@85004,COG2606@1,COG2606@2 NA|NA|NA S Aminoacyl-tRNA editing domain NIBLCNGB_00898 326426.Bbr_1348 0.0 1208.4 Bifidobacteriales aspS GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2GJHU@201174,4CYWQ@85004,COG0173@1,COG0173@2 NA|NA|NA J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) NIBLCNGB_00899 1437610.BREU_0948 5.9e-261 906.4 Bifidobacteriales hisS 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GIYJ@201174,4CYR9@85004,COG0124@1,COG0124@2 NA|NA|NA J Histidyl-tRNA synthetase NIBLCNGB_00900 326426.Bbr_1350 4.4e-224 783.9 Bifidobacteriales 3.1.26.12,3.2.1.8 ko:K01181,ko:K08300,ko:K08301 ko03018,map03018 M00394 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Bacteria 2I2EC@201174,4CYYM@85004,COG3266@1,COG3266@2 NA|NA|NA S Domain of Unknown Function (DUF349) NIBLCNGB_00901 326426.Bbr_1351 0.0 1114.4 Bifidobacteriales 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 2GKC3@201174,4D0CZ@85004,COG0737@1,COG0737@2 NA|NA|NA F 5'-nucleotidase, C-terminal domain NIBLCNGB_00902 1341695.BBOMB_1372 9.6e-59 234.2 Bifidobacteriales lipA Bacteria 2HGIX@201174,4CZUK@85004,COG0657@1,COG0657@2 NA|NA|NA I Hydrolase, alpha beta domain protein NIBLCNGB_00903 1437610.BREU_0420 3e-132 478.8 Bifidobacteriales xylE GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 2.A.1.1 Bacteria 2HC9X@201174,4D2XP@85004,COG0477@1,COG0477@2 NA|NA|NA U Sugar (and other) transporter NIBLCNGB_00904 401473.BDP_1318 3e-26 125.9 Bifidobacteriales Bacteria 2I65M@201174,4D17X@85004,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein NIBLCNGB_00905 326426.Bbr_1356 0.0 1581.2 Bifidobacteriales clpC ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 2GJ77@201174,4CZCH@85004,COG0542@1,COG0542@2 NA|NA|NA O ATPase family associated with various cellular activities (AAA) NIBLCNGB_00906 326426.Bbr_1357 2.4e-178 631.3 Bifidobacteriales uspA Bacteria 2IA7S@201174,4CZZ0@85004,COG0589@1,COG0589@2 NA|NA|NA T Belongs to the universal stress protein A family NIBLCNGB_00907 326426.Bbr_1358 1.4e-176 625.5 Bifidobacteriales Bacteria 28NWB@1,2GJ74@201174,2ZBU7@2,4CYW9@85004 NA|NA|NA S Protein of unknown function (DUF3027) NIBLCNGB_00908 326426.Bbr_1359 1.7e-66 258.5 Bifidobacteriales cspB ko:K03704 ko00000,ko03000 Bacteria 2IKXN@201174,4D0V4@85004,COG1278@1,COG1278@2 NA|NA|NA K 'Cold-shock' DNA-binding domain NIBLCNGB_00909 326426.Bbr_1360 0.0 1126.7 Bifidobacteriales 2.7.13.3 ko:K02484,ko:K07768 ko02020,map02020 M00443 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2I2DU@201174,4CZNF@85004,COG2770@1,COG2770@2,COG5002@1,COG5002@2 NA|NA|NA T ATPase histidine kinase DNA gyrase B HSP90 domain protein NIBLCNGB_00910 326426.Bbr_1361 2e-132 478.4 Bifidobacteriales Bacteria 2GIZB@201174,4CYPS@85004,COG0745@1,COG0745@2 NA|NA|NA KT Response regulator receiver domain protein NIBLCNGB_00911 326426.Bbr_1362 1.3e-100 372.9 Bifidobacteriales Bacteria 2B59T@1,2HZNR@201174,31Y3Y@2,4D12Q@85004 NA|NA|NA NIBLCNGB_00912 326426.Bbr_1363 4.2e-33 147.1 Bifidobacteriales Bacteria 2GQI8@201174,4D17K@85004,COG4842@1,COG4842@2 NA|NA|NA S Proteins of 100 residues with WXG NIBLCNGB_00913 326426.Bbr_1364 2.7e-291 1007.3 Bifidobacteriales groL GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016465,GO:0022610,GO:0030112,GO:0030312,GO:0030313,GO:0031975,GO:0032991,GO:0036293,GO:0040007,GO:0042026,GO:0042603,GO:0043388,GO:0044093,GO:0044183,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051704,GO:0061077,GO:0065007,GO:0065009,GO:0070482,GO:0071944,GO:0101031,GO:1990220,GO:2000677,GO:2000679 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 2GKC9@201174,4CZJK@85004,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions NIBLCNGB_00914 326426.Bbr_1365 6.1e-38 162.9 Bifidobacteriales ko:K03704 ko00000,ko03000 Bacteria 2GQRU@201174,4D1FB@85004,COG1278@1,COG1278@2 NA|NA|NA K 'Cold-shock' DNA-binding domain NIBLCNGB_00915 326426.Bbr_1366 2.4e-84 318.5 Bifidobacteriales Bacteria 2DP6P@1,2GQYA@201174,330SA@2,4CZYT@85004 NA|NA|NA S LytR cell envelope-related transcriptional attenuator NIBLCNGB_00916 326426.Bbr_1367 3.8e-133 480.7 Bifidobacteriales ung GO:0003674,GO:0003824,GO:0004844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJ9Z@201174,4CZ3Y@85004,COG0692@1,COG0692@2 NA|NA|NA L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine NIBLCNGB_00917 326426.Bbr_1368 1.4e-187 662.1 Bifidobacteriales moxR ko:K03924 ko00000,ko01000 Bacteria 2GK07@201174,4CZ2I@85004,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) NIBLCNGB_00918 326426.Bbr_1369 1.1e-162 579.3 Bifidobacteriales Bacteria 2GKSJ@201174,4CYYD@85004,COG1721@1,COG1721@2 NA|NA|NA S Protein of unknown function DUF58 NIBLCNGB_00919 326426.Bbr_1370 3.9e-85 320.9 Bifidobacteriales Bacteria 2AUTC@1,2IKRN@201174,31KGE@2,4D134@85004 NA|NA|NA NIBLCNGB_00920 326426.Bbr_1371 3.3e-189 667.5 Bifidobacteriales ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2I9VM@201174,4CZ00@85004,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor (vWF) type A domain NIBLCNGB_00921 326426.Bbr_1372 1e-153 549.7 Bifidobacteriales ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2GJMP@201174,4CZ8P@85004,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor (vWF) type A domain NIBLCNGB_00922 326426.Bbr_1373 3.1e-56 224.9 Bifidobacteriales Bacteria 2BG6D@1,2IR67@201174,32A37@2,4D18W@85004 NA|NA|NA NIBLCNGB_00923 326426.Bbr_1375 9.9e-254 882.5 Bifidobacteriales Bacteria 2IHFB@201174,4CZ17@85004,COG1075@1,COG1075@2 NA|NA|NA S PGAP1-like protein NIBLCNGB_00924 326426.Bbr_1376 2.2e-111 408.3 Bifidobacteriales ykoE ko:K16925 M00582 ko00000,ko00002,ko02000 3.A.1.30 Bacteria 2H5VZ@201174,4CZ6M@85004,COG4721@1,COG4721@2 NA|NA|NA S ABC-type cobalt transport system, permease component NIBLCNGB_00925 326426.Bbr_1377 4.7e-279 966.5 Bifidobacteriales purB GO:0003674,GO:0003824,GO:0004018,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 iAF1260.b1131,iBWG_1329.BWG_0979,iE2348C_1286.E2348C_1272,iEC042_1314.EC042_1202,iECABU_c1320.ECABU_c13450,iECDH10B_1368.ECDH10B_1203,iECP_1309.ECP_1126,iECUMN_1333.ECUMN_1375,iETEC_1333.ETEC_1255,iEcHS_1320.EcHS_A1251,iEcolC_1368.EcolC_2472,iJO1366.b1131,iJR904.b1131,iLF82_1304.LF82_1774,iNRG857_1313.NRG857_05460,iY75_1357.Y75_RS05905,ic_1306.c1510 Bacteria 2GM71@201174,4CYV6@85004,COG0015@1,COG0015@2 NA|NA|NA F Adenylosuccinate lyase C-terminal NIBLCNGB_00926 326426.Bbr_1378 0.0 1595.1 Bifidobacteriales Bacteria 2GMAV@201174,4CYRT@85004,COG0392@1,COG0392@2 NA|NA|NA S Lysylphosphatidylglycerol synthase TM region NIBLCNGB_00927 326426.Bbr_1379 8.1e-42 176.0 Bifidobacteriales hup GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 2IKQR@201174,4D11V@85004,COG0776@1,COG0776@2 NA|NA|NA L Belongs to the bacterial histone-like protein family NIBLCNGB_00928 326426.Bbr_1380 8.6e-284 982.2 Bifidobacteriales pafA GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 ko:K13571 M00342 R11207 RC00090,RC00096 ko00000,ko00002,ko01000,ko03051 Bacteria 2GMC6@201174,4CZ12@85004,COG0638@1,COG0638@2 NA|NA|NA O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine NIBLCNGB_00930 326426.Bbr_1382 8.9e-175 619.4 Bifidobacteriales hisN 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2HGP2@201174,4CYWZ@85004,COG0483@1,COG0483@2 NA|NA|NA G Inositol monophosphatase family NIBLCNGB_00931 326426.Bbr_1383 0.0 1104.0 Bifidobacteriales dop GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119,6.3.1.19 ko:K13571,ko:K20814 M00342 R11207 RC00090,RC00096 ko00000,ko00002,ko01000,ko03051 Bacteria 2GJGI@201174,4CZAN@85004,COG4122@1,COG4122@2 NA|NA|NA S Pup-ligase protein NIBLCNGB_00932 326426.Bbr_1384 6.1e-134 483.4 Bifidobacteriales alsE GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019313,GO:0019314,GO:0019316,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0034700,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046367,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783,ko:K17195 ko00030,ko00040,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529,R09031 RC00540,RC03111 ko00000,ko00001,ko00002,ko01000 iEcSMS35_1347.EcSMS35_4551 Bacteria 2IC1U@201174,4CZWV@85004,COG0036@1,COG0036@2 NA|NA|NA G Ribulose-phosphate 3 epimerase family NIBLCNGB_00933 326426.Bbr_1385 1.1e-161 576.2 Bifidobacteriales ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.2.1 Bacteria 2GJU4@201174,4CZ60@85004,COG1299@1,COG1299@2 NA|NA|NA G Phosphotransferase System NIBLCNGB_00934 326426.Bbr_1386 2.1e-46 191.4 Bifidobacteriales fruA 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 Bacteria 2IPEN@201174,4D113@85004,COG1445@1,COG1445@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit NIBLCNGB_00935 326426.Bbr_1387 1.1e-78 299.3 Bifidobacteriales 2.7.1.194,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02821 ko00051,ko00053,ko01100,ko01120,ko02060,map00051,map00053,map01100,map01120,map02060 M00273,M00283,M00550 R03232,R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.7.1 Bacteria 2IMPP@201174,4D0WI@85004,COG1762@1,COG1762@2 NA|NA|NA G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 NIBLCNGB_00936 326426.Bbr_1388 2.6e-71 274.6 Bifidobacteriales Bacteria 2BIQA@1,2GTDU@201174,32CXN@2,4D1IN@85004 NA|NA|NA H Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 NIBLCNGB_00937 326426.Bbr_1389 2.9e-279 967.2 Bifidobacteriales manR ko:K02538 ko00000,ko03000 Bacteria 2HXN0@201174,4D049@85004,COG3711@1,COG3711@2 NA|NA|NA K PRD domain NIBLCNGB_00938 326426.Bbr_1390 2.5e-132 478.0 Bifidobacteriales 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 R05287 RC00697 ko00000,ko00001,ko01000 Bacteria 2I8XE@201174,4CZGV@85004,COG1011@1,COG1011@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase NIBLCNGB_00939 326426.Bbr_1391 1.3e-285 988.4 Bifidobacteriales arc GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 ko:K13525,ko:K13527 ko03050,ko04141,ko05134,map03050,map04141,map05134 M00342,M00400,M00403 ko00000,ko00001,ko00002,ko03019,ko03051,ko04131,ko04147 3.A.16.1 Bacteria 2GMR1@201174,4CZ86@85004,COG1222@1,COG1222@2 NA|NA|NA O AAA ATPase forming ring-shaped complexes NIBLCNGB_00940 326426.Bbr_1392 9.4e-124 449.5 Bifidobacteriales apl 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 2GN43@201174,4CZZA@85004,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein NIBLCNGB_00941 326426.Bbr_1393 7.2e-119 433.3 Bifidobacteriales serB 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 Bacteria 2GJDH@201174,4CYWC@85004,COG0560@1,COG0560@2 NA|NA|NA E haloacid dehalogenase-like hydrolase NIBLCNGB_00942 326426.Bbr_1394 0.0 1492.2 Bifidobacteriales priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKES@201174,4D04J@85004,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA NIBLCNGB_00943 326426.Bbr_1395 2.5e-132 478.0 Bifidobacteriales 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 R05287 RC00697 ko00000,ko00001,ko01000 Bacteria 2I8XE@201174,4CZGV@85004,COG1011@1,COG1011@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase NIBLCNGB_00944 326426.Bbr_1396 1.8e-184 651.7 Bifidobacteriales fmt GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.1.176,2.1.2.9 ko:K00604,ko:K03500 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000,ko03009 iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048 Bacteria 2GKH5@201174,4CZ8C@85004,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus NIBLCNGB_00945 326426.Bbr_1397 0.0 1188.7 Bifidobacteriales ilvD GO:0003674,GO:0003824,GO:0004160,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1259,iECIAI39_1322.ECIAI39_3015 Bacteria 2GJIJ@201174,4CZ1T@85004,COG0129@1,COG0129@2 NA|NA|NA H Belongs to the IlvD Edd family NIBLCNGB_00946 326426.Bbr_1398 4.2e-46 190.3 Bifidobacteriales rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2IQHU@201174,4D12C@85004,COG1758@1,COG1758@2 NA|NA|NA K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits NIBLCNGB_00947 326426.Bbr_1399 5e-229 800.0 Bifidobacteriales metK GO:0000096,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006556,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009069,GO:0009108,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0019752,GO:0019899,GO:0030312,GO:0030554,GO:0030955,GO:0031420,GO:0032553,GO:0032555,GO:0032559,GO:0033353,GO:0034641,GO:0035375,GO:0035639,GO:0036094,GO:0040007,GO:0042278,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046872,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901605,GO:1901657 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 iJN678.metX,iJN746.PP_4967,iYL1228.KPN_03375 Bacteria 2GJ4U@201174,4CZ5D@85004,COG0192@1,COG0192@2 NA|NA|NA H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme NIBLCNGB_00948 1437609.BCAL_0365 1.8e-41 175.3 Bifidobacteriales GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K07485 ko00000 Bacteria 2GJK7@201174,4D0ME@85004,COG3464@1,COG3464@2 NA|NA|NA L Transposase NIBLCNGB_00949 326426.Bbr_1414 0.0 2251.9 Bifidobacteriales ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GK9M@201174,4CYT7@85004,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) NIBLCNGB_00950 326426.Bbr_1415 1.1e-135 489.6 Bifidobacteriales rbsK 2.7.1.15 ko:K00852 ko00030,map00030 R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2I04R@201174,4CZIB@85004,COG0524@1,COG0524@2 NA|NA|NA H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway NIBLCNGB_00951 1193128.A200_02539 1.1e-168 599.7 Bifidobacteriales ko:K08168 M00704 ko00000,ko00002,ko01504,ko02000 2.A.1.3.16,2.A.1.3.22,2.A.1.3.6 Bacteria 2GJV6@201174,4CZH3@85004,COG0477@1,COG0477@2 NA|NA|NA EGP Major Facilitator Superfamily NIBLCNGB_00952 1120933.ATUY01000006_gene1213 6.8e-139 500.4 Actinobacteria rihA_2 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 Bacteria 2GP6N@201174,4D4IS@85005,COG1957@1,COG1957@2 NA|NA|NA F Inosine-uridine preferring nucleoside hydrolase NIBLCNGB_00953 216816.GS08_07920 2.7e-135 488.4 Bifidobacteriales rbsR ko:K02529 ko00000,ko03000 Bacteria 2GNVD@201174,4CZNG@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor NIBLCNGB_00954 326426.Bbr_1433 0.0 1291.6 Bifidobacteriales ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,4CZPJ@85004,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region NIBLCNGB_00955 216816.GS08_07930 0.0 1117.1 Bifidobacteriales ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,4CZMX@85004,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter, ATP-binding protein NIBLCNGB_00956 326426.Bbr_1435 5.2e-90 337.0 Bifidobacteriales Bacteria 2IIWT@201174,4D0WT@85004,COG1846@1,COG1846@2 NA|NA|NA K MarR family NIBLCNGB_00957 158787.BSCA_0785 0.0 1287.7 Bifidobacteriales bglB 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 GH3 Bacteria 2GJ5H@201174,4CZ2P@85004,COG1472@1,COG1472@2 NA|NA|NA G Glycosyl hydrolase family 3 N-terminal domain protein NIBLCNGB_00958 1437610.BREU_0902 1.3e-86 325.9 Bifidobacteriales Bacteria 2I8DN@201174,4CZXN@85004,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family NIBLCNGB_00959 1437603.BMON_1706 3.8e-104 384.8 Bifidobacteriales Bacteria 2HGIX@201174,4CZUK@85004,COG0657@1,COG0657@2 NA|NA|NA I Hydrolase, alpha beta domain protein NIBLCNGB_00960 1437603.BMON_1705 8.6e-248 862.8 Bifidobacteriales ko:K06978 ko00000 Bacteria 2GK8B@201174,4D21R@85004,COG2936@1,COG2936@2 NA|NA|NA S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain NIBLCNGB_00961 1437603.BMON_1704 7.6e-164 583.6 Bifidobacteriales Bacteria 2GVNB@201174,4CZGZ@85004,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily NIBLCNGB_00962 1437603.BMON_1703 3.9e-73 281.2 Bifidobacteriales Bacteria 2I8DN@201174,4D2T6@85004,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family NIBLCNGB_00963 1437608.BBIA_2163 4.4e-40 171.8 Bifidobacteriales Bacteria 2B8XW@1,2H6J9@201174,3228D@2,4D2B4@85004 NA|NA|NA NIBLCNGB_00964 326426.Bbr_1438 7.6e-238 829.3 Bifidobacteriales 3.2.1.58 ko:K01210 ko00500,map00500 R00308,R03115 RC00467 ko00000,ko00001,ko01000 Bacteria 2I8WH@201174,4CZV7@85004,COG2730@1,COG2730@2 NA|NA|NA G Belongs to the glycosyl hydrolase 5 (cellulase A) family NIBLCNGB_00965 326426.Bbr_1439 1.3e-69 268.9 Bifidobacteriales Bacteria 2IJSQ@201174,4D0XU@85004,COG1669@1,COG1669@2 NA|NA|NA S Nucleotidyltransferase substrate binding protein like NIBLCNGB_00966 326426.Bbr_1440 1.6e-45 188.3 Bifidobacteriales Bacteria 2IMP4@201174,4D145@85004,COG1669@1,COG1669@2 NA|NA|NA S Nucleotidyltransferase domain NIBLCNGB_00968 326426.Bbr_1442 0.0 1573.9 Bifidobacteriales bgl2 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 GH3 Bacteria 2GJ5H@201174,4CZT6@85004,COG1472@1,COG1472@2 NA|NA|NA G Fibronectin type III-like domain NIBLCNGB_00969 326426.Bbr_1443 9.6e-129 466.1 Bifidobacteriales Bacteria 2I8DN@201174,4D2T6@85004,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family NIBLCNGB_00970 326426.Bbr_1444 5.5e-255 886.3 Bifidobacteriales gshA 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJPI@201174,4CYZP@85004,COG3572@1,COG3572@2 NA|NA|NA H Glutamate-cysteine ligase family 2(GCS2) NIBLCNGB_00971 326426.Bbr_1445 0.0 3184.0 Bifidobacteriales hgdC Bacteria 2I1VH@201174,4CZ6Y@85004,COG1924@1,COG1924@2,COG3580@1,COG3580@2,COG3581@1,COG3581@2 NA|NA|NA I CoA enzyme activase uncharacterised domain (DUF2229) NIBLCNGB_00972 326426.Bbr_1446 2.2e-136 491.5 Bifidobacteriales nrdG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0031250,GO:0032991,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 1.97.1.4 ko:K04068 R04710 ko00000,ko01000 iE2348C_1286.E2348C_4563 Bacteria 2H0HA@201174,4CYSC@85004,COG0602@1,COG0602@2 NA|NA|NA O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine NIBLCNGB_00973 326426.Bbr_1447 0.0 1658.3 Bifidobacteriales nrdD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019001,GO:0019103,GO:0019438,GO:0019637,GO:0019692,GO:0030554,GO:0031250,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032556,GO:0032558,GO:0032559,GO:0032560,GO:0032564,GO:0032567,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0046872,GO:0046914,GO:0051065,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_4713,iPC815.YPO3454 Bacteria 2GMGA@201174,4CYV3@85004,COG1328@1,COG1328@2 NA|NA|NA F Anaerobic ribonucleoside-triphosphate reductase NIBLCNGB_00974 326426.Bbr_1448 6.9e-256 889.4 Bifidobacteriales xseA GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.1.11.6 ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJAS@201174,4CZU4@85004,COG1570@1,COG1570@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides NIBLCNGB_00975 326426.Bbr_1449 3.5e-40 170.6 Bifidobacteriales xseB GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GR0U@201174,4D18C@85004,COG1722@1,COG1722@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides NIBLCNGB_00976 326426.Bbr_1450 5.1e-91 340.5 Bifidobacteriales ywrO 1.6.5.2 ko:K00355,ko:K11748 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000,ko02000 2.A.37.1.2 Bacteria 2HZE1@201174,4D11H@85004,COG2249@1,COG2249@2 NA|NA|NA S Flavodoxin-like fold NIBLCNGB_00977 326426.Bbr_1451 0.0 1239.9 Bifidobacteriales fadD 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2GIXQ@201174,4CYYC@85004,COG1022@1,COG1022@2 NA|NA|NA I AMP-binding enzyme NIBLCNGB_00978 326426.Bbr_1452 3.2e-65 254.6 Bifidobacteriales mscL GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 ko:K03282 ko00000,ko02000 1.A.22.1 Bacteria 2IQDN@201174,4D13A@85004,COG1970@1,COG1970@2 NA|NA|NA M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell NIBLCNGB_00979 326426.Bbr_1453 3.7e-78 297.4 Bifidobacteriales Bacteria 2IHGG@201174,4D0T2@85004,COG3613@1,COG3613@2 NA|NA|NA F Nucleoside 2-deoxyribosyltransferase NIBLCNGB_00981 326426.Bbr_1454 1.6e-200 705.3 Bifidobacteriales ko:K18353 ko01502,ko02020,map01502,map02020 M00651 ko00000,ko00001,ko00002,ko01504 Bacteria 2I2GX@201174,4CYTX@85004,COG3568@1,COG3568@2 NA|NA|NA S Endonuclease/Exonuclease/phosphatase family NIBLCNGB_00982 326426.Bbr_1455 4.9e-179 633.6 Bifidobacteriales ppx GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 2GMME@201174,4CYW8@85004,COG0248@1,COG0248@2 NA|NA|NA FP Ppx/GppA phosphatase family NIBLCNGB_00983 326426.Bbr_1456 3.3e-233 813.9 Bifidobacteriales aspB Bacteria 2GJ7R@201174,4CZQP@85004,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase class-V NIBLCNGB_00984 326426.Bbr_1457 8.5e-201 706.1 Bifidobacteriales afr_2 Bacteria 2GKW0@201174,4CYXG@85004,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold NIBLCNGB_00985 326426.Bbr_1458 7.4e-88 329.7 Bifidobacteriales vsr ko:K07458 ko00000,ko01000,ko03400 Bacteria 2IKPY@201174,4D0R6@85004,COG3727@1,COG3727@2 NA|NA|NA L May nick specific sequences that contain T G mispairs resulting from m5C-deamination NIBLCNGB_00986 326426.Bbr_1459 1.2e-100 372.5 Bifidobacteriales XK27_03610 Bacteria 2II91@201174,4D0SH@85004,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain NIBLCNGB_00987 326426.Bbr_1460 0.0 2625.9 Bifidobacteriales snf 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 2GISC@201174,4CZSD@85004,COG0553@1,COG0553@2,COG4715@1,COG4715@2 NA|NA|NA KL Psort location Cytoplasmic, score 8.87 NIBLCNGB_00988 326426.Bbr_1461 8.9e-147 526.6 Bifidobacteriales dapD GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1201c Bacteria 2GIZ9@201174,4CYVT@85004,COG2171@1,COG2171@2 NA|NA|NA E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA NIBLCNGB_00989 326426.Bbr_1462 2.4e-250 870.9 Bifidobacteriales gltA GO:0003674,GO:0003824,GO:0004108,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0036440,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046912,GO:0055114,GO:0071704,GO:0071944,GO:0072350 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 iIT341.HP0026,iYL1228.KPN_00727 Bacteria 2GJ7E@201174,4CZ2J@85004,COG0372@1,COG0372@2 NA|NA|NA C Citrate synthase, C-terminal domain NIBLCNGB_00990 326426.Bbr_1463 6e-151 540.0 Bifidobacteriales map 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 2GKKB@201174,4CZAA@85004,COG0024@1,COG0024@2 NA|NA|NA E Methionine aminopeptidase NIBLCNGB_00991 326426.Bbr_1464 1.5e-142 512.3 Bifidobacteriales Bacteria 2H3AT@201174,4D00R@85004,COG3247@1,COG3247@2 NA|NA|NA S Short repeat of unknown function (DUF308) NIBLCNGB_00992 326426.Bbr_1465 0.0 1470.7 Bifidobacteriales pepO 3.4.24.71 ko:K01415,ko:K07386 ko00000,ko01000,ko01002,ko04147 Bacteria 2GNJY@201174,4CYVU@85004,COG3590@1,COG3590@2 NA|NA|NA O Peptidase family M13 NIBLCNGB_00993 326426.Bbr_1466 2.2e-117 428.3 Bifidobacteriales ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 2GQIQ@201174,4D17E@85004,COG0629@1,COG0629@2 NA|NA|NA L Single-strand binding protein family NIBLCNGB_00994 326426.Bbr_1467 0.0 1208.4 Bifidobacteriales proS GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GJ9G@201174,4CZ6E@85004,COG0442@1,COG0442@2 NA|NA|NA J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS NIBLCNGB_00995 216816.GS08_08175 2.2e-100 371.7 Bifidobacteriales pflA 1.97.1.4 ko:K04069 R04710 ko00000,ko01000 Bacteria 2HZHC@201174,4D0G1@85004,COG1180@1,COG1180@2 NA|NA|NA O Radical SAM superfamily NIBLCNGB_00996 216816.GS08_08185 4.2e-264 916.8 Bifidobacteriales recD2 3.6.4.12 ko:K15255 ko00000,ko01000,ko03029,ko03032 Bacteria 2HFY1@201174,4CZ0C@85004,COG0507@1,COG0507@2 NA|NA|NA L PIF1-like helicase NIBLCNGB_00997 216816.GS08_08190 7e-121 439.9 Bifidobacteriales orn GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2GJR7@201174,4CYZY@85004,COG1949@1,COG1949@2 NA|NA|NA L 3'-to-5' exoribonuclease specific for small oligoribonucleotides NIBLCNGB_00998 762211.BSTEL_1108 4.4e-129 467.6 Bifidobacteriales Bacteria 2GJBJ@201174,4D00W@85004,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding protein-like domain NIBLCNGB_00999 1437609.BCAL_0483 1.6e-188 665.2 Bifidobacteriales 3.2.1.10,3.2.1.20,3.2.1.93 ko:K01182,ko:K01187,ko:K01226 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R00837,R01718,R01791,R06087,R06088,R06113,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13,GH31 Bacteria 2GKS4@201174,4CZ1E@85004,COG0366@1,COG0366@2 NA|NA|NA G Alpha-amylase domain NIBLCNGB_01000 1437609.BCAL_0483 1.3e-62 245.7 Bifidobacteriales 3.2.1.10,3.2.1.20,3.2.1.93 ko:K01182,ko:K01187,ko:K01226 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R00837,R01718,R01791,R06087,R06088,R06113,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13,GH31 Bacteria 2GKS4@201174,4CZ1E@85004,COG0366@1,COG0366@2 NA|NA|NA G Alpha-amylase domain NIBLCNGB_01001 762211.BSTEL_1110 3.6e-119 434.9 Bifidobacteriales Bacteria 2GJZG@201174,4CZ93@85004,COG2211@1,COG2211@2 NA|NA|NA G Transporter major facilitator family protein NIBLCNGB_01003 1236504.HMPREF2132_02335 2.7e-15 88.2 Bacteroidia 2.1.1.72 ko:K07317 ko00000,ko01000,ko02048 Bacteria 2FQ1D@200643,4NEHR@976,COG0827@1,COG0827@2,COG1002@1,COG1002@2 NA|NA|NA L COG1002 Type II restriction enzyme methylase subunits NIBLCNGB_01004 1127131.WEISSC39_10660 1.2e-221 776.9 Leuconostocaceae 2.1.1.72 ko:K07317 ko00000,ko01000,ko02048 Bacteria 1UXW6@1239,4AYSX@81850,4IF28@91061,COG0827@1,COG0827@2,COG1002@1,COG1002@2 NA|NA|NA LV Eco57I restriction-modification methylase NIBLCNGB_01005 1095726.HMPREF1116_1511 3.1e-202 712.6 Bacilli Bacteria 1TQH0@1239,4HAQK@91061,COG0553@1,COG0553@2 NA|NA|NA L SNF2 family N-terminal domain NIBLCNGB_01006 326426.Bbr_1472 4.8e-293 1013.1 Bifidobacteriales guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GITZ@201174,4CZ2S@85004,COG0516@1,COG0516@2,COG0517@1,COG0517@2 NA|NA|NA F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth NIBLCNGB_01007 326426.Bbr_1473 5.1e-213 746.9 Bifidobacteriales tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 ko:K02851 R08856 RC00002 ko00000,ko01000,ko01003,ko01005 Bacteria 2GIT7@201174,4CZ4P@85004,COG0472@1,COG0472@2 NA|NA|NA M Glycosyl transferase family 4 NIBLCNGB_01008 326426.Bbr_1474 1.5e-118 432.2 Bifidobacteriales ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 2GK2X@201174,4CYVA@85004,COG0009@1,COG0009@2 NA|NA|NA J Belongs to the SUA5 family NIBLCNGB_01009 326426.Bbr_1475 2.5e-124 451.4 Bifidobacteriales livF ko:K01996 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 2GKSQ@201174,4CZE0@85004,COG0410@1,COG0410@2 NA|NA|NA E ATPases associated with a variety of cellular activities NIBLCNGB_01010 326426.Bbr_1476 2.4e-161 574.7 Bifidobacteriales ko:K01995 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 2GMEE@201174,4CZBX@85004,COG0411@1,COG0411@2 NA|NA|NA E Branched-chain amino acid ATP-binding cassette transporter NIBLCNGB_01011 326426.Bbr_1477 1.4e-187 662.1 Bifidobacteriales livM ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 2GJB3@201174,4CYTE@85004,COG4177@1,COG4177@2 NA|NA|NA U Belongs to the binding-protein-dependent transport system permease family NIBLCNGB_01012 326426.Bbr_1478 5.4e-111 407.5 Bifidobacteriales ko:K01997 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 2GMAY@201174,4CZQ6@85004,COG0559@1,COG0559@2 NA|NA|NA U Belongs to the binding-protein-dependent transport system permease family NIBLCNGB_01013 326426.Bbr_1479 1.8e-207 728.4 Bifidobacteriales livK ko:K01999 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 2GM00@201174,4CZYU@85004,COG0683@1,COG0683@2 NA|NA|NA E Receptor family ligand binding region NIBLCNGB_01014 326426.Bbr_1480 2.4e-164 584.7 Bifidobacteriales prmC 2.1.1.297 ko:K02493 R10806 RC00003,RC03279 ko00000,ko01000,ko03012 Bacteria 2GMH1@201174,4CZB3@85004,COG2890@1,COG2890@2 NA|NA|NA J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif NIBLCNGB_01015 326426.Bbr_1481 3.7e-191 674.1 Bifidobacteriales prfA ko:K02835 ko00000,ko03012 Bacteria 2GJWG@201174,4CYX4@85004,COG0216@1,COG0216@2 NA|NA|NA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA NIBLCNGB_01016 216816.GS08_08225 1.3e-36 158.3 Bifidobacteriales rpmE GO:0008150,GO:0040007 ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ4I@201174,4D17F@85004,COG0254@1,COG0254@2 NA|NA|NA J Binds the 23S rRNA NIBLCNGB_01018 326426.Bbr_1483 2.7e-98 364.8 Bifidobacteriales yebQ GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 ko:K08169 ko00000,ko02000 2.A.1.3.17 Bacteria 2GIZX@201174,4CZWX@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily NIBLCNGB_01019 326426.Bbr_1484 2.4e-147 528.1 Bifidobacteriales Bacteria 2A54I@1,2IETW@201174,30TT6@2,4CZX3@85004 NA|NA|NA NIBLCNGB_01020 158787.BSCA_2217 1.5e-68 265.4 Bifidobacteriales def2 3.5.1.31,3.5.1.88 ko:K01450,ko:K01462 ko00270,ko00630,map00270,map00630 R00653 RC00165,RC00323 ko00000,ko00001,ko01000 Bacteria 2IJQ5@201174,4D14S@85004,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins NIBLCNGB_01021 326426.Bbr_1486 6e-165 586.6 Bifidobacteriales dkgB Bacteria 2GJQ7@201174,4CYUN@85004,COG0656@1,COG0656@2 NA|NA|NA S Oxidoreductase, aldo keto reductase family protein NIBLCNGB_01022 158787.BSCA_2219 1.3e-19 101.7 Bifidobacteriales lmrB ko:K03466,ko:K18926 M00715 ko00000,ko00002,ko02000,ko03036 2.A.1.3.30,3.A.12 Bacteria 2I2QX@201174,4CZRY@85004,COG0477@1,COG0477@2 NA|NA|NA U Major Facilitator Superfamily NIBLCNGB_01023 326426.Bbr_1487 4.8e-88 330.5 Bifidobacteriales Bacteria 2IHK6@201174,4D0T3@85004,COG1846@1,COG1846@2 NA|NA|NA K Winged helix DNA-binding domain NIBLCNGB_01024 216816.GS08_08420 1.9e-175 621.7 Bifidobacteriales glkA GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJCQ@201174,4CZF6@85004,COG1940@1,COG1940@2 NA|NA|NA G ROK family NIBLCNGB_01026 326426.Bbr_1489 1.2e-308 1065.1 Bifidobacteriales Bacteria 2GIUM@201174,4D0BX@85004,COG0477@1,COG0477@2 NA|NA|NA EGP Major Facilitator Superfamily NIBLCNGB_01027 326426.Bbr_1490 0.0 1115.9 Bifidobacteriales yjjK GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 Bacteria 2GKBQ@201174,4CYWH@85004,COG0488@1,COG0488@2 NA|NA|NA S ATP-binding cassette protein, ChvD family NIBLCNGB_01028 326426.Bbr_1491 2.5e-169 601.3 Bifidobacteriales tesB ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Bacteria 2GJ1B@201174,4CZRC@85004,COG1946@1,COG1946@2 NA|NA|NA I Thioesterase-like superfamily NIBLCNGB_01029 326426.Bbr_1492 1e-85 322.8 Bifidobacteriales Bacteria 2DRQG@1,2HZP6@201174,33CMQ@2,4D14M@85004 NA|NA|NA S Protein of unknown function (DUF3180) NIBLCNGB_01030 326426.Bbr_1493 6.5e-226 790.0 Bifidobacteriales folK GO:0000287,GO:0003674,GO:0003824,GO:0003848,GO:0005488,GO:0008150,GO:0016740,GO:0016772,GO:0016778,GO:0040007,GO:0043167,GO:0043169,GO:0046872 1.13.11.81,2.5.1.15,2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01495,ko:K01633,ko:K13940,ko:K17488 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841,M00842,M00843 R00428,R03066,R03067,R03503,R03504,R04639,R05046,R05048,R10348,R11037,R11073 RC00002,RC00017,RC00121,RC00263,RC00294,RC00323,RC00721,RC00842,RC00943,RC00945,RC01188,RC01479,RC02504,RC03131,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 iECDH1ME8569_1439.ECDH1ME8569_0136,iEcDH1_1363.EcDH1_3460,iJN746.PP_4698,iLJ478.TM0041,iSBO_1134.SBO_0131 Bacteria 2H3G6@201174,4D0EJ@85004,COG0801@1,COG0801@2,COG1539@1,COG1539@2 NA|NA|NA H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin NIBLCNGB_01031 326426.Bbr_1494 1.4e-161 575.5 Bifidobacteriales folP 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503,R03504,R11037,R11073 RC00002,RC00017,RC00121,RC00721,RC00842,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJDQ@201174,4CZWW@85004,COG0294@1,COG0294@2 NA|NA|NA H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives NIBLCNGB_01032 216816.GS08_08460 1.1e-96 359.4 Bifidobacteriales folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R03503,R04639,R05046,R05048 RC00002,RC00017,RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 iIT341.HP0928 Bacteria 2GP2P@201174,4CZ5S@85004,COG0302@1,COG0302@2 NA|NA|NA H GTP cyclohydrolase NIBLCNGB_01033 326426.Bbr_1496 0.0 1268.4 Bifidobacteriales ftsH GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 ko:K03798 M00742 ko00000,ko00002,ko01000,ko01002,ko03110 Bacteria 2GJ4Q@201174,4CZ6U@85004,COG0465@1,COG0465@2 NA|NA|NA O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins NIBLCNGB_01034 326426.Bbr_1497 2.7e-97 361.3 Bifidobacteriales hpt 2.4.2.8,6.3.4.19 ko:K00760,ko:K04075,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 2GMDZ@201174,4CZNJ@85004,COG0634@1,COG0634@2 NA|NA|NA F Belongs to the purine pyrimidine phosphoribosyltransferase family NIBLCNGB_01035 326426.Bbr_1498 8.3e-210 736.1 Bifidobacteriales tilS 2.4.2.8,6.3.4.19 ko:K00760,ko:K04075,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 2GJR4@201174,4CYSY@85004,COG0037@1,COG0037@2 NA|NA|NA J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine NIBLCNGB_01036 326426.Bbr_1499 1.5e-248 865.1 Bifidobacteriales dacB 3.4.16.4 ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 2GJPH@201174,4CYXQ@85004,COG2027@1,COG2027@2 NA|NA|NA M D-Ala-D-Ala carboxypeptidase 3 (S13) family NIBLCNGB_01037 326426.Bbr_1500 2.6e-297 1027.3 Bifidobacteriales ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2BWH2@1,2GMNW@201174,2Z89R@2,4CZP3@85004 NA|NA|NA NIBLCNGB_01038 326426.Bbr_1501 2.3e-190 671.4 Bifidobacteriales natA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GIY8@201174,4CZ0Q@85004,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities NIBLCNGB_01039 326426.Bbr_1502 1.6e-235 821.6 Bifidobacteriales epsG ko:K00786 ko00000,ko01000 Bacteria 2HZ9V@201174,4CZ5J@85004,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family 21 NIBLCNGB_01040 326426.Bbr_1503 1.6e-280 971.5 Bifidobacteriales Bacteria 2GN4Y@201174,4CZD1@85004,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter NIBLCNGB_01041 326426.Bbr_1504 4.7e-179 633.6 Bifidobacteriales 3.4.14.13 ko:K20742 ko00000,ko01000,ko01002 Bacteria 2GNPU@201174,4CZ7E@85004,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 NIBLCNGB_01042 326426.Bbr_1505 5.2e-204 716.8 Bifidobacteriales fucO GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006004,GO:0006066,GO:0008150,GO:0008152,GO:0008198,GO:0008912,GO:0009056,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019299,GO:0019301,GO:0019317,GO:0019318,GO:0019320,GO:0019751,GO:0034311,GO:0034313,GO:0042354,GO:0042355,GO:0042844,GO:0042846,GO:0043167,GO:0043169,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0046365,GO:0046872,GO:0046914,GO:0051143,GO:0055114,GO:0071704,GO:1901575,GO:1901615,GO:1901616 1.1.1.1,1.1.1.77,1.1.99.37,1.2.98.1 ko:K00048,ko:K13954,ko:K17067 ko00010,ko00071,ko00350,ko00625,ko00626,ko00630,ko00640,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00630,map00640,map00680,map01100,map01110,map01120,map01130,map01200,map01220 R00614,R00623,R00754,R01781,R02257,R04880,R05233,R05234,R06917,R06927 RC00034,RC00050,RC00087,RC00088,RC00099,RC00116,RC00188,RC00649 ko00000,ko00001,ko01000 iAF1260.b2799,iECDH1ME8569_1439.ECDH1ME8569_2709,iECSE_1348.ECSE_3059,iECW_1372.ECW_m3009,iEKO11_1354.EKO11_0969,iEcDH1_1363.EcDH1_0889,iEcE24377_1341.EcE24377A_3104,iEcHS_1320.EcHS_A2943,iJO1366.b2799,iJR904.b2799,iUMNK88_1353.UMNK88_3484,iWFL_1372.ECW_m3009,iY75_1357.Y75_RS14565 Bacteria 2I2FD@201174,4CZ71@85004,COG1454@1,COG1454@2 NA|NA|NA C Iron-containing alcohol dehydrogenase NIBLCNGB_01043 326426.Bbr_1506 3.6e-262 910.2 Bifidobacteriales cma 2.1.1.79 ko:K00574 ko00000,ko01000 Bacteria 2GJ94@201174,4D016@85004,COG2230@1,COG2230@2 NA|NA|NA M Mycolic acid cyclopropane synthetase NIBLCNGB_01046 326426.Bbr_1507 7.6e-161 573.2 Bifidobacteriales trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02493,ko:K02527,ko:K03439 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763,R10806 RC00003,RC00009,RC00077,RC00247,RC03279 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko03012,ko03016 GT30 Bacteria 2GJ8R@201174,4CZKF@85004,COG0220@1,COG0220@2 NA|NA|NA J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA NIBLCNGB_01048 1437608.BBIA_0825 2.6e-11 74.3 Bifidobacteriales Bacteria 2AWD3@1,2IP9B@201174,31N90@2,4D14C@85004 NA|NA|NA NIBLCNGB_01049 1437608.BBIA_0824 2.2e-21 107.5 Bifidobacteriales Bacteria 2BA3Q@1,2H863@201174,323HI@2,4D2FS@85004 NA|NA|NA NIBLCNGB_01050 1437609.BCAL_0532 4.3e-233 813.5 Bifidobacteriales Bacteria 29W79@1,2IC42@201174,30HSG@2,4CZCZ@85004 NA|NA|NA S Helix-turn-helix domain NIBLCNGB_01051 1437609.BCAL_0534 8e-83 313.2 Bifidobacteriales ko:K18955 ko00000,ko03000 Bacteria 2A2Z4@1,2IDG0@201174,30RDK@2,4D038@85004 NA|NA|NA S Transcription factor WhiB NIBLCNGB_01052 1437608.BBIA_0821 4.9e-103 380.6 Bifidobacteriales parA ko:K03496 ko00000,ko03036,ko04812 Bacteria 2ICWE@201174,4D14U@85004,COG1192@1,COG1192@2 NA|NA|NA D AAA domain NIBLCNGB_01053 1437608.BBIA_0820 1.7e-35 154.8 Bifidobacteriales Bacteria 2AYK3@1,2ISGT@201174,31QQD@2,4D1C9@85004 NA|NA|NA NIBLCNGB_01054 1437609.BCAL_0537 1.3e-69 268.9 Bifidobacteriales Bacteria 2BH3J@1,2IHK5@201174,32B4F@2,4D0RP@85004 NA|NA|NA NIBLCNGB_01055 1437610.BREU_1736 2.2e-22 111.7 Bifidobacteriales Bacteria 2B6SJ@1,2IQ17@201174,31ZRP@2,4D142@85004 NA|NA|NA NIBLCNGB_01057 216816.GS08_09725 5.5e-125 453.8 Bifidobacteriales Bacteria 2A74Q@1,2ISJ1@201174,30W0F@2,4D1A8@85004 NA|NA|NA NIBLCNGB_01058 1437610.BREU_1663 1.3e-271 941.8 Bifidobacteriales Bacteria 2IH2Y@201174,4D0R4@85004,COG1106@1,COG1106@2 NA|NA|NA S Psort location Cytoplasmic, score NIBLCNGB_01059 1437608.BBIA_0816 0.0 2679.0 Bifidobacteriales sprF 4.6.1.1 ko:K01768,ko:K21449 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko02000 1.B.40.2 Bacteria 2I2HK@201174,4D2VM@85004,COG3064@1,COG3064@2 NA|NA|NA M Cell surface antigen C-terminus NIBLCNGB_01060 58344.JOEL01000018_gene5379 9.6e-41 174.1 Bacteria ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria COG1131@1,COG1131@2 NA|NA|NA V ATPase activity NIBLCNGB_01061 1206731.BAGB01000062_gene7626 4.6e-17 95.9 Nocardiaceae ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Bacteria 2GPKJ@201174,4G7S7@85025,COG4403@1,COG4403@2 NA|NA|NA V Lanthionine synthetase C-like protein NIBLCNGB_01062 762211.BSTEL_0148 3.5e-85 321.2 Bifidobacteriales Bacteria 2F10A@1,2IAKS@201174,33U1T@2,4D01S@85004 NA|NA|NA NIBLCNGB_01063 216816.GS08_05140 1.6e-126 458.8 Bifidobacteriales Bacteria 2EXFX@1,2IC7Z@201174,33QS8@2,4CZUQ@85004 NA|NA|NA NIBLCNGB_01064 216816.GS08_05135 2e-120 438.3 Bifidobacteriales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IEJK@201174,4D0K4@85004,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities NIBLCNGB_01066 1437610.BREU_1728 1.9e-98 365.5 Bifidobacteriales lacR ko:K02529 ko00000,ko03000 Bacteria 2H5ZG@201174,4CZ8A@85004,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family NIBLCNGB_01067 1437609.BCAL_0547 1.6e-194 685.3 Bifidobacteriales Bacteria 2C746@1,2IPH7@201174,340R4@2,4D1XT@85004 NA|NA|NA NIBLCNGB_01068 1437610.BREU_1726 1e-133 482.6 Bifidobacteriales ytrE ko:K02003,ko:K10038 ko02010,map02010 M00227,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.3.2 Bacteria 2ICH8@201174,4D0ET@85004,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter NIBLCNGB_01069 1437610.BREU_1725 2.2e-188 664.8 Bifidobacteriales Bacteria 2I9EN@201174,4D24X@85004,COG3023@1,COG3023@2 NA|NA|NA V Putative peptidoglycan binding domain NIBLCNGB_01070 1437609.BCAL_0550 1.2e-118 432.6 Bifidobacteriales Bacteria 2F769@1,2IS95@201174,33ZMP@2,4D2UK@85004 NA|NA|NA NIBLCNGB_01071 1437610.BREU_1723 2.9e-48 198.0 Bifidobacteriales Bacteria 2B6Z5@1,2H351@201174,31ZZC@2,4D1UJ@85004 NA|NA|NA NIBLCNGB_01072 1437609.BCAL_0552 4.6e-120 437.2 Bifidobacteriales Bacteria 2GKYV@201174,4D0I8@85004,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C terminal NIBLCNGB_01073 1437609.BCAL_0553 1.9e-231 808.1 Bifidobacteriales qseC GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0042221,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 ko:K02484,ko:K07637,ko:K07643,ko:K07645,ko:K07649,ko:K07653,ko:K18351 ko01502,ko01503,ko02020,ko02024,map01502,map01503,map02020,map02024 M00444,M00451,M00453,M00457,M00460,M00651,M00658,M00709,M00721,M00722,M00723,M00724,M00744 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 Bacteria 2I436@201174,4D205@85004,COG0642@1,COG0642@2 NA|NA|NA T GHKL domain NIBLCNGB_01074 1437610.BREU_1720 3.5e-97 360.9 Bifidobacteriales ko:K22108 ko00000,ko03000 Bacteria 2HZZ1@201174,4D2BM@85004,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator NIBLCNGB_01075 1437609.BCAL_0555 6.4e-37 159.8 Bifidobacteriales Bacteria 2A2CR@1,2H4YY@201174,30QPR@2,4D27C@85004 NA|NA|NA NIBLCNGB_01076 1437608.BBIA_0810 8.1e-31 139.0 Bifidobacteriales Bacteria 2EJJI@1,2GW42@201174,33DAG@2,4D1C7@85004 NA|NA|NA NIBLCNGB_01077 1437610.BREU_1717 5.5e-142 510.4 Bifidobacteriales Bacteria 2B0U3@1,2IDXF@201174,31T6M@2,4D01Y@85004 NA|NA|NA NIBLCNGB_01078 1437609.BCAL_0558 8.6e-63 246.1 Bifidobacteriales Bacteria 29YW1@1,2HZKD@201174,30KSH@2,4D0T1@85004 NA|NA|NA S PrgI family protein NIBLCNGB_01079 1437609.BCAL_0559 5.9e-39 167.2 Bifidobacteriales trsE Bacteria 2H6W2@201174,4CYWV@85004,COG3451@1,COG3451@2 NA|NA|NA U type IV secretory pathway VirB4 NIBLCNGB_01080 1437609.BCAL_0575 2.4e-73 281.6 Bifidobacteriales Bacteria 2B5AP@1,2GVFX@201174,31VDH@2,4D1E8@85004 NA|NA|NA S Domain of unknown function (DUF4192) NIBLCNGB_01081 326426.Bbr_0152 9.8e-296 1021.9 Bifidobacteriales Bacteria 2IBDV@201174,4CZS6@85004,COG4584@1,COG4584@2 NA|NA|NA L PFAM Integrase catalytic NIBLCNGB_01082 326426.Bbr_0151 3.6e-148 530.8 Bifidobacteriales Bacteria 2H714@201174,4CZRM@85004,COG1484@1,COG1484@2 NA|NA|NA L IstB-like ATP binding protein NIBLCNGB_01083 1147128.BAST_0865 1.7e-78 298.9 Bifidobacteriales ko:K18955 ko00000,ko03000 Bacteria 2A2Z4@1,2IDG0@201174,30RDK@2,4D038@85004 NA|NA|NA S Transcription factor WhiB NIBLCNGB_01084 326426.Bbr_1513 1.3e-100 372.5 Bifidobacteriales parA ko:K03496 ko00000,ko03036,ko04812 Bacteria 2ICWE@201174,4D14U@85004,COG1192@1,COG1192@2 NA|NA|NA D AAA domain NIBLCNGB_01085 326426.Bbr_1514 2.6e-39 167.5 Bifidobacteriales Bacteria 2AYK3@1,2ISGT@201174,31QQD@2,4D1C9@85004 NA|NA|NA NIBLCNGB_01086 216816.GS08_08570 1.2e-280 971.8 Bifidobacteriales ko:K15738,ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 3.A.1.120.6,3.A.1.121.1,3.A.1.121.3 Bacteria 2GKZC@201174,4CZ9C@85004,COG0488@1,COG0488@2 NA|NA|NA S ATPases associated with a variety of cellular activities NIBLCNGB_01087 326426.Bbr_1516 2.2e-93 348.2 Bifidobacteriales Bacteria 2IQQX@201174,4D1CY@85004,COG0454@1,COG0456@2 NA|NA|NA K FR47-like protein NIBLCNGB_01088 326426.Bbr_1517 1.3e-119 435.6 Bifidobacteriales serB 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 Bacteria 2HZV3@201174,4D1VN@85004,COG0560@1,COG0560@2 NA|NA|NA E haloacid dehalogenase-like hydrolase NIBLCNGB_01089 326426.Bbr_1518 0.0 1835.5 Bifidobacteriales XK27_00515 Bacteria 2HRQY@201174,4CYQ9@85004,COG3087@1,COG3087@2 NA|NA|NA D Cell surface antigen C-terminus NIBLCNGB_01090 1147128.BAST_0873 1.5e-272 944.9 Bifidobacteriales XK27_00515 Bacteria 2HRQY@201174,4CYQ9@85004,COG3087@1,COG3087@2 NA|NA|NA D Cell surface antigen C-terminus NIBLCNGB_01091 78346.BRUM_1918 2.4e-44 184.9 Bifidobacteriales Bacteria 2BM73@1,2HZUH@201174,32FQT@2,4D1TW@85004 NA|NA|NA S Helix-turn-helix domain NIBLCNGB_01092 78346.BRUM_1919 1.8e-61 242.3 Bifidobacteriales Bacteria 2IMP1@201174,4D13G@85004,COG1569@1,COG1569@2 NA|NA|NA S PIN domain NIBLCNGB_01093 326426.Bbr_1527 6.2e-31 139.4 Bifidobacteriales Bacteria 2EJJI@1,2GW42@201174,33DAG@2,4D1C7@85004 NA|NA|NA NIBLCNGB_01094 326426.Bbr_1528 1.1e-145 522.7 Bifidobacteriales Bacteria 2B0U3@1,2IDXF@201174,31T6M@2,4D01Y@85004 NA|NA|NA NIBLCNGB_01095 1437609.BCAL_0558 1.1e-41 176.0 Bifidobacteriales Bacteria 29YW1@1,2HZKD@201174,30KSH@2,4D0T1@85004 NA|NA|NA S PrgI family protein NIBLCNGB_01096 1437609.BCAL_0559 0.0 1131.7 Bifidobacteriales trsE Bacteria 2H6W2@201174,4CYWV@85004,COG3451@1,COG3451@2 NA|NA|NA U type IV secretory pathway VirB4 NIBLCNGB_01097 326426.Bbr_1530 4.5e-201 707.6 Bifidobacteriales isp2 3.2.1.96 ko:K01227,ko:K07347,ko:K17733,ko:K21471 ko00511,ko05133,map00511,map05133 ko00000,ko00001,ko01000,ko01002,ko01011,ko02000,ko02035,ko02044 1.B.11.3 Bacteria 2I9VT@201174,4D074@85004,COG0741@1,COG0741@2,COG3942@1,COG3942@2 NA|NA|NA M CHAP domain NIBLCNGB_01098 326426.Bbr_1531 1.2e-84 320.1 Bifidobacteriales Bacteria 2AQRU@1,2IABZ@201174,31FZM@2,4D0HM@85004 NA|NA|NA NIBLCNGB_01099 1211112.ALJC01000089_gene753 7.1e-86 324.7 Gammaproteobacteria mloB Bacteria 1MXG1@1224,1RY9W@1236,COG2865@1,COG2865@2 NA|NA|NA K Putative ATP-dependent DNA helicase recG C-terminal NIBLCNGB_01101 702459.BBPR_0055 2.7e-41 174.5 Bifidobacteriales ko:K07483 ko00000 Bacteria 2IQ8F@201174,4D15Y@85004,COG2963@1,COG2963@2 NA|NA|NA L Transposase NIBLCNGB_01102 1437600.JDUI01000007_gene734 3.1e-146 524.6 Bifidobacteriales tnp7109-21 Bacteria 2GKDY@201174,4CZUB@85004,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain NIBLCNGB_01103 326426.Bbr_1536 1e-159 569.3 Bifidobacteriales ko:K03205 ko03070,map03070 M00333 ko00000,ko00001,ko00002,ko02044 3.A.7 Bacteria 2HZ9D@201174,4CZ1V@85004,COG3505@1,COG3505@2 NA|NA|NA U Type IV secretory system Conjugative DNA transfer NIBLCNGB_01104 1437608.BBIA_0816 8.8e-13 79.3 Bifidobacteriales sprF 4.6.1.1 ko:K01768,ko:K21449 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko02000 1.B.40.2 Bacteria 2I2HK@201174,4D2VM@85004,COG3064@1,COG3064@2 NA|NA|NA M Cell surface antigen C-terminus NIBLCNGB_01105 326426.Bbr_1551 2.8e-266 924.1 Bifidobacteriales lacS ko:K03292,ko:K11104,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.1,2.A.2.2 Bacteria 2HD4Y@201174,4CZRA@85004,COG2211@1,COG2211@2 NA|NA|NA G Psort location CytoplasmicMembrane, score 10.00 NIBLCNGB_01106 326426.Bbr_1552 0.0 2166.0 Bifidobacteriales lacL 3.2.1.23 ko:K01190,ko:K12111 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 Bacteria 2GMAT@201174,4CYYS@85004,COG3250@1,COG3250@2 NA|NA|NA G Psort location Cytoplasmic, score 8.87 NIBLCNGB_01107 326426.Bbr_1553 4.8e-185 653.7 Bifidobacteriales lacR ko:K02529 ko00000,ko03000 Bacteria 2H5ZG@201174,4CZ8A@85004,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family NIBLCNGB_01108 216816.GS08_07340 2.8e-22 110.9 Bifidobacteriales Bacteria 2H4CW@201174,4D25Y@85004,COG2826@1,COG2826@2 NA|NA|NA L Helix-turn-helix domain NIBLCNGB_01109 326426.Bbr_1554 4e-248 863.6 Bifidobacteriales ko:K02027,ko:K10240 ko02010,map02010 M00206,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.23 Bacteria 2GJIP@201174,4D0C5@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_01110 326426.Bbr_1555 3.3e-214 750.7 Bifidobacteriales Bacteria 2GKMZ@201174,4CZUF@85004,COG1940@1,COG1940@2 NA|NA|NA GK ROK family NIBLCNGB_01111 326426.Bbr_1556 0.0 1368.6 Bifidobacteriales Bacteria 2HZCI@201174,4CZS1@85004,COG3525@1,COG3525@2 NA|NA|NA G Glycosyl hydrolase family 20, domain 2 NIBLCNGB_01112 77635.BISU_2462 6.7e-08 62.4 Bifidobacteriales Bacteria 2GKW1@201174,4CYXY@85004,COG2801@1,COG2801@2,COG2963@1,COG2963@2 NA|NA|NA L HTH-like domain NIBLCNGB_01113 702459.BBPR_1469 8.9e-219 766.1 Bifidobacteriales vex3 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2I99G@201174,4D0H6@85004,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease NIBLCNGB_01114 326426.Bbr_1559 6.8e-210 736.5 Bifidobacteriales vex1 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IA7B@201174,4CZJM@85004,COG0577@1,COG0577@2 NA|NA|NA V Efflux ABC transporter, permease protein NIBLCNGB_01115 216816.GS08_02130 1.4e-110 405.6 Bifidobacteriales vex2 ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2I7UV@201174,4CZ1C@85004,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein NIBLCNGB_01116 216816.GS08_08595 6.4e-12 76.6 Bifidobacteriales azlC Bacteria 2HZA0@201174,4CZ7Q@85004,COG1296@1,COG1296@2 NA|NA|NA E AzlC protein NIBLCNGB_01117 326426.Bbr_1562 5e-96 357.1 Bifidobacteriales ptpA GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 ko:K01104,ko:K20945 ko05111,map05111 ko00000,ko00001,ko01000 Bacteria 2IM0Q@201174,4CZWM@85004,COG0394@1,COG0394@2 NA|NA|NA T low molecular weight NIBLCNGB_01118 326426.Bbr_1563 3e-127 461.1 Bifidobacteriales folA GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070401,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2763c Bacteria 2IM1S@201174,4CZM1@85004,COG0262@1,COG0262@2 NA|NA|NA H dihydrofolate reductase NIBLCNGB_01119 216816.GS08_08615 7.8e-168 596.3 Bifidobacteriales thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKY0@201174,4CZQ3@85004,COG0207@1,COG0207@2 NA|NA|NA F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis NIBLCNGB_01120 326426.Bbr_1565 3.4e-73 280.8 Bifidobacteriales attW GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2IIK7@201174,4D0PB@85004,COG1765@1,COG1765@2 NA|NA|NA O OsmC-like protein NIBLCNGB_01121 326426.Bbr_1566 3.6e-188 664.1 Bifidobacteriales Bacteria 2GMFE@201174,4CZ6V@85004,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein family NIBLCNGB_01122 326426.Bbr_1567 3.9e-101 374.4 Bifidobacteriales ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 2GJX7@201174,4D01Q@85004,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family NIBLCNGB_01123 326426.Bbr_1568 1.4e-101 375.9 Bifidobacteriales ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 2IBQZ@201174,4CYXI@85004,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family NIBLCNGB_01124 326426.Bbr_1569 1.7e-168 598.6 Bifidobacteriales usp 3.5.1.28 ko:K21471,ko:K22409 ko00000,ko01000,ko01002,ko01011 CBM50 Bacteria 2GP2A@201174,4CYXV@85004,COG3942@1,COG3942@2 NA|NA|NA S CHAP domain NIBLCNGB_01125 326426.Bbr_1570 1.7e-210 738.4 Bifidobacteriales serC GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GKYK@201174,4CZ94@85004,COG1932@1,COG1932@2 NA|NA|NA E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine NIBLCNGB_01126 216816.GS08_08650 8.1e-33 146.0 Bifidobacteriales Bacteria 2EG1H@1,2IQTR@201174,339TH@2,4D16E@85004 NA|NA|NA NIBLCNGB_01127 326426.Bbr_1572 1.8e-170 605.5 Bifidobacteriales Bacteria 2GJY7@201174,4CZIM@85004,COG5002@1,COG5002@2 NA|NA|NA T ATPase histidine kinase DNA gyrase B HSP90 domain protein NIBLCNGB_01128 326426.Bbr_1573 5.4e-116 423.7 Bifidobacteriales phoU ko:K02039 ko00000 Bacteria 2GKAD@201174,4CZ9B@85004,COG0704@1,COG0704@2 NA|NA|NA P Plays a role in the regulation of phosphate uptake NIBLCNGB_01129 326426.Bbr_1574 1.1e-138 499.2 Bifidobacteriales gpmA GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2GK8F@201174,4CZMF@85004,COG0588@1,COG0588@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate NIBLCNGB_01130 326426.Bbr_1575 6.8e-173 613.2 Bifidobacteriales menA GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 iECH74115_1262.ECH74115_5387,iG2583_1286.G2583_4737 Bacteria 2GJBS@201174,4CZHQ@85004,COG1575@1,COG1575@2 NA|NA|NA H Belongs to the MenA family. Type 1 subfamily NIBLCNGB_01131 216816.GS08_08675 1.2e-310 1071.6 Bifidobacteriales lysS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF1260.b4129,iECDH1ME8569_1439.ECDH1ME8569_3989,iECW_1372.ECW_m4490,iEcDH1_1363.EcDH1_3862,iJN678.lysS,iJO1366.b4129,iWFL_1372.ECW_m4490 Bacteria 2GKE0@201174,4CZHM@85004,COG1190@1,COG1190@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family NIBLCNGB_01133 326426.Bbr_1577 1.8e-215 755.0 Bifidobacteriales araJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K08156,ko:K19577 ko00000,ko02000 2.A.1.2.14,2.A.1.2.65 Bacteria 2GK8C@201174,4CZ46@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily NIBLCNGB_01134 326426.Bbr_1578 0.0 1365.5 Bifidobacteriales Bacteria 2I7P1@201174,4CZTS@85004,COG0457@1,COG0457@2 NA|NA|NA S Domain of unknown function (DUF4037) NIBLCNGB_01135 326426.Bbr_1579 1.4e-110 405.6 Bifidobacteriales Bacteria 2DM2Z@1,2GKMX@201174,31HGC@2,4CZJ9@85004 NA|NA|NA S Protein of unknown function (DUF4125) NIBLCNGB_01136 326426.Bbr_1580 0.0 1088.6 Bifidobacteriales ko:K06889 ko00000 Bacteria 2H036@201174,4CYRR@85004,COG1073@1,COG1073@2 NA|NA|NA S alpha beta NIBLCNGB_01137 326426.Bbr_1581 2.2e-67 262.3 Bifidobacteriales Bacteria 2BIES@1,2GSGC@201174,32CM6@2,4D1KF@85004 NA|NA|NA NIBLCNGB_01138 326426.Bbr_1582 1.8e-285 988.0 Bifidobacteriales pspC Bacteria 2GIVS@201174,4CZZT@85004,COG1983@1,COG1983@2 NA|NA|NA KT PspC domain NIBLCNGB_01139 326426.Bbr_1583 1.1e-237 828.9 Bifidobacteriales tcsS3 Bacteria 2GJ4J@201174,4CZ2U@85004,COG1983@1,COG1983@2,COG4585@1,COG4585@2 NA|NA|NA KT PspC domain NIBLCNGB_01140 326426.Bbr_1584 4.4e-118 430.6 Bifidobacteriales degU ko:K07684 ko02020,map02020 M00471 ko00000,ko00001,ko00002,ko02022 Bacteria 2GIVA@201174,4CZW8@85004,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon NIBLCNGB_01141 326426.Bbr_1585 4.1e-168 597.4 Bifidobacteriales galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMCW@201174,4CZDB@85004,COG1087@1,COG1087@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family NIBLCNGB_01142 326426.Bbr_1586 2.6e-205 721.1 Bifidobacteriales mdsC 2.7.1.162,2.7.1.39 ko:K02204,ko:K13059 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771,R08962 RC00002,RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2I8JD@201174,4D06K@85004,COG2334@1,COG2334@2 NA|NA|NA S Phosphotransferase enzyme family NIBLCNGB_01143 326426.Bbr_1587 0.0 1570.1 Bifidobacteriales gnpA GO:0003674,GO:0003824,GO:0004645,GO:0005975,GO:0008150,GO:0008152,GO:0016740,GO:0016757,GO:0016758,GO:0044238,GO:0050500,GO:0071704 2.4.1.211 ko:K15533 ko00000,ko01000 Bacteria 2GN2A@201174,4CYZB@85004,COG5426@1,COG5426@2 NA|NA|NA S Lacto-N-biose phosphorylase C-terminal domain NIBLCNGB_01144 326426.Bbr_1588 2.5e-167 594.7 Bifidobacteriales ko:K02026 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GJPZ@201174,4CYV5@85004,COG0395@1,COG0395@2 NA|NA|NA G ABC transporter permease NIBLCNGB_01145 326426.Bbr_1589 6.9e-173 613.2 Bifidobacteriales malC ko:K02025,ko:K10118,ko:K10241,ko:K15771 ko02010,map02010 M00196,M00206,M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.23,3.A.1.1.28 Bacteria 2GMTW@201174,4CZX2@85004,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component NIBLCNGB_01146 326426.Bbr_1590 1.2e-249 868.6 Bifidobacteriales ko:K02027,ko:K10240 ko02010,map02010 M00206,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.23 Bacteria 2GJIP@201174,4CZ88@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_01148 326426.Bbr_1591 3.3e-242 844.0 Bifidobacteriales serS GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GIWP@201174,4CZ40@85004,COG0172@1,COG0172@2 NA|NA|NA J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) NIBLCNGB_01149 326426.Bbr_1592 3e-207 727.6 Bifidobacteriales Bacteria 2GJ3K@201174,4CYTC@85004,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain NIBLCNGB_01150 326426.Bbr_1593 8.6e-162 576.2 Bifidobacteriales arbG ko:K02538,ko:K03488 ko00000,ko03000 Bacteria 2I8K8@201174,4D08T@85004,COG3711@1,COG3711@2 NA|NA|NA K CAT RNA binding domain NIBLCNGB_01151 326426.Bbr_1594 0.0 1234.2 Bifidobacteriales crr GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006109,GO:0006793,GO:0006796,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009892,GO:0009898,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045912,GO:0048519,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071944,GO:0080090,GO:0098552,GO:0098562 2.7.1.193 ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02803,ko:K02804 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00267,M00268,M00270,M00271,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R05199,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 e_coli_core.b2417,iAF1260.b2417,iAPECO1_1312.APECO1_4128,iB21_1397.B21_02278,iBWG_1329.BWG_2179,iE2348C_1286.E2348C_2603,iEC042_1314.EC042_2626,iEC55989_1330.EC55989_2707,iECABU_c1320.ECABU_c27380,iECBD_1354.ECBD_1264,iECB_1328.ECB_02317,iECDH10B_1368.ECDH10B_2582,iECDH1ME8569_1439.ECDH1ME8569_2351,iECD_1391.ECD_02317,iECED1_1282.ECED1_2861,iECH74115_1262.ECH74115_3648,iECIAI1_1343.ECIAI1_2475,iECIAI39_1322.ECIAI39_2563,iECNA114_1301.ECNA114_2494,iECO103_1326.ECO103_2936,iECO111_1330.ECO111_3147,iECO26_1355.ECO26_3470,iECOK1_1307.ECOK1_2734,iECS88_1305.ECS88_2607,iECSE_1348.ECSE_2708,iECSF_1327.ECSF_2281,iECSP_1301.ECSP_3365,iECUMN_1333.ECUMN_2739,iECW_1372.ECW_m2646,iEKO11_1354.EKO11_1311,iETEC_1333.ETEC_2530,iEcDH1_1363.EcDH1_1244,iEcE24377_1341.EcE24377A_2704,iEcHS_1320.EcHS_A2552,iEcSMS35_1347.EcSMS35_2572,iEcolC_1368.EcolC_1261,iG2583_1286.G2583_2949,iJO1366.b2417,iJR904.b2417,iLF82_1304.LF82_0357,iNRG857_1313.NRG857_12120,iSFV_1184.SFV_2469,iSF_1195.SF2472,iSFxv_1172.SFxv_2721,iSSON_1240.SSON_2506,iS_1188.S2618,iUMN146_1321.UM146_04535,iUMNK88_1353.UMNK88_3019,iUTI89_1310.UTI89_C2751,iWFL_1372.ECW_m2646,iY75_1357.Y75_RS12665,ic_1306.c2952 Bacteria 2GK6B@201174,4CZR7@85004,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G pts system, glucose-specific IIABC component NIBLCNGB_01152 326426.Bbr_1595 0.0 1120.5 Bifidobacteriales pgm GO:0000271,GO:0003674,GO:0003824,GO:0004614,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005996,GO:0006006,GO:0006012,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0016868,GO:0019318,GO:0019320,GO:0019388,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0055114,GO:0071704,GO:1901575,GO:1901576 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1376,iECED1_1282.ECED1_0670,iECNA114_1301.ECNA114_0627,iECOK1_1307.ECOK1_0699,iECP_1309.ECP_0709,iECS88_1305.ECS88_0725,iJN678.pgm,iLF82_1304.LF82_1632,iNRG857_1313.NRG857_03110,iUMN146_1321.UM146_14115,iYL1228.KPN_00711 Bacteria 2H1PI@201174,4CZ7X@85004,COG0033@1,COG0033@2 NA|NA|NA G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II NIBLCNGB_01153 326426.Bbr_1596 8.9e-198 696.0 Bifidobacteriales gmk 1.1.1.23,2.7.4.8 ko:K00013,ko:K00942 ko00230,ko00340,ko01100,ko01110,ko01230,map00230,map00340,map01100,map01110,map01230 M00026,M00050 R00332,R01158,R01163,R02090,R03012 RC00002,RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 Bacteria 2HTNX@201174,4D0CP@85004,COG2852@1,COG2852@2 NA|NA|NA S Protein conserved in bacteria NIBLCNGB_01154 326426.Bbr_1597 1.9e-74 285.0 Bifidobacteriales ko:K19587 M00767 ko00000,ko00002,ko03000 Bacteria 2IKDG@201174,4D0YZ@85004,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator NIBLCNGB_01155 326426.Bbr_1598 1.5e-275 954.9 Bifidobacteriales merA GO:0000302,GO:0000305,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0019725,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901530,GO:1901700,GO:1990748 1.16.1.1,1.8.1.7 ko:K00383,ko:K00520,ko:K21739 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 2GJJK@201174,4CZZF@85004,COG1249@1,COG1249@2 NA|NA|NA C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family NIBLCNGB_01156 326426.Bbr_1599 1e-172 612.8 Bifidobacteriales rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2GK53@201174,4CZGC@85004,COG0328@1,COG0328@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids NIBLCNGB_01157 326426.Bbr_1600 9.1e-127 459.5 Bifidobacteriales rpiA GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,5.3.1.6 ko:K00851,ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056,R01737 RC00002,RC00017,RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMHW@201174,4CZDH@85004,COG0120@1,COG0120@2 NA|NA|NA G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate NIBLCNGB_01159 326426.Bbr_1602 2.3e-97 361.7 Bifidobacteriales Bacteria 2EHBK@1,2ICD4@201174,33B3F@2,4CZY5@85004 NA|NA|NA NIBLCNGB_01160 326426.Bbr_1603 3.6e-261 907.1 Bifidobacteriales radA GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K04485 ko00000,ko03400 Bacteria 2GMQ0@201174,4CZE1@85004,COG1066@1,COG1066@2 NA|NA|NA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function NIBLCNGB_01161 326426.Bbr_1604 4.3e-219 766.9 Bifidobacteriales ribF GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKQF@201174,4CYXT@85004,COG0196@1,COG0196@2 NA|NA|NA H riboflavin kinase NIBLCNGB_01162 326426.Bbr_1605 2.7e-219 767.7 Bifidobacteriales truB GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 ko00000,ko01000,ko03016 Bacteria 2GJZK@201174,4CZED@85004,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs NIBLCNGB_01163 326426.Bbr_1606 4e-81 307.4 Bifidobacteriales rbfA ko:K02834 ko00000,ko03009 Bacteria 2IKXP@201174,4CZZZ@85004,COG0858@1,COG0858@2 NA|NA|NA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA NIBLCNGB_01164 326426.Bbr_1607 0.0 1360.9 Bifidobacteriales infB ko:K02519 ko00000,ko03012,ko03029 Bacteria 2GKPH@201174,4CZ4B@85004,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex NIBLCNGB_01165 326426.Bbr_1608 1.6e-183 648.7 Bifidobacteriales nusA ko:K02600 ko00000,ko03009,ko03021 Bacteria 2GJDJ@201174,4CYTW@85004,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination NIBLCNGB_01166 326426.Bbr_1609 8.9e-125 453.0 Bifidobacteriales Bacteria 2B54U@1,2HXKT@201174,31XYD@2,4D0IH@85004 NA|NA|NA NIBLCNGB_01167 216816.GS08_08925 4.9e-100 370.9 Bifidobacteriales Bacteria 2GJ5Q@201174,4D040@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor NIBLCNGB_01169 326426.Bbr_1611 7.4e-149 533.1 Bifidobacteriales Bacteria 2GN5D@201174,4CZBJ@85004,COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase/protease-like homologues NIBLCNGB_01170 326426.Bbr_1612 0.0 1464.1 Bifidobacteriales gcs2 Bacteria 2GN0J@201174,4D061@85004,COG2307@1,COG2307@2,COG2308@1,COG2308@2 NA|NA|NA S A circularly permuted ATPgrasp NIBLCNGB_01171 326426.Bbr_1613 8.7e-170 602.8 Bifidobacteriales truA GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 2GJ6C@201174,4CZ8H@85004,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs NIBLCNGB_01172 326426.Bbr_1614 2e-62 245.4 Bifidobacteriales rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 ko:K02879 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHV2@201174,4D0PZ@85004,COG0203@1,COG0203@2 NA|NA|NA J Ribosomal protein L17 NIBLCNGB_01173 326426.Bbr_1615 3.4e-183 647.5 Bifidobacteriales rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2GJJ5@201174,4CZEN@85004,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates NIBLCNGB_01174 216816.GS08_08970 1.5e-65 255.4 Bifidobacteriales rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02948 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFFC@201174,4D0PJ@85004,COG0100@1,COG0100@2 NA|NA|NA J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome NIBLCNGB_01175 326426.Bbr_1617 9.5e-62 242.7 Bifidobacteriales rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02952 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHPN@201174,4D0PQ@85004,COG0099@1,COG0099@2 NA|NA|NA J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits NIBLCNGB_01176 158787.BSCA_1163 8.4e-14 81.6 Bifidobacteriales rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02919 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GWMH@201174,4D1NT@85004,COG0257@1,COG0257@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL36 family NIBLCNGB_01177 1435051.BMOU_1728 1.6e-32 144.8 Bifidobacteriales infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009986,GO:0016020,GO:0030246,GO:0030247,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 2IQ4B@201174,4D16H@85004,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex NIBLCNGB_01178 326426.Bbr_1620 1.1e-98 365.9 Bifidobacteriales adk 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJ7T@201174,4CZ7Z@85004,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism NIBLCNGB_01179 216816.GS08_08995 3.8e-246 857.1 Bifidobacteriales secY GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5 Bacteria 2GJ26@201174,4CYWU@85004,COG0201@1,COG0201@2 NA|NA|NA U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently NIBLCNGB_01180 326426.Bbr_1622 8.1e-76 289.7 Bifidobacteriales rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02876 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2II6M@201174,4D0R9@85004,COG0200@1,COG0200@2 NA|NA|NA J binds to the 23S rRNA NIBLCNGB_01181 216816.GS08_09005 9.2e-26 122.1 Bifidobacteriales rpmD GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02907 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQV0@201174,4D1EZ@85004,COG1841@1,COG1841@2 NA|NA|NA J Ribosomal protein L30p/L7e NIBLCNGB_01182 326426.Bbr_1624 6.7e-96 357.1 Bifidobacteriales rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02988 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJW8@201174,4CZCD@85004,COG0098@1,COG0098@2 NA|NA|NA J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body NIBLCNGB_01183 326426.Bbr_1625 2.4e-57 228.0 Bifidobacteriales rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02881 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKTX@201174,4D0WE@85004,COG0256@1,COG0256@2 NA|NA|NA J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance NIBLCNGB_01184 326426.Bbr_1626 5.4e-95 353.6 Bifidobacteriales rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02933 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GK35@201174,4CYQV@85004,COG0097@1,COG0097@2 NA|NA|NA J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center NIBLCNGB_01185 1437610.BREU_0623 5.5e-68 263.5 Bifidobacteriales rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02994 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHQZ@201174,4D0P6@85004,COG0096@1,COG0096@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit NIBLCNGB_01186 1437609.BCAL_1317 9.2e-18 95.5 Bifidobacteriales rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ8R@201174,4D177@85004,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site NIBLCNGB_01187 326426.Bbr_1629 4.4e-103 380.6 Bifidobacteriales rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02931 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJW7@201174,4CZCA@85004,COG0094@1,COG0094@2 NA|NA|NA J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits NIBLCNGB_01188 326426.Bbr_1630 1.3e-51 208.8 Bifidobacteriales rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02895 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKP2@201174,4D10I@85004,COG0198@1,COG0198@2 NA|NA|NA J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit NIBLCNGB_01189 216816.GS08_09045 6.6e-60 236.5 Bifidobacteriales rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02874 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHNX@201174,4D0VI@85004,COG0093@1,COG0093@2 NA|NA|NA J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome NIBLCNGB_01190 216816.GS08_09050 6.4e-41 172.9 Bifidobacteriales rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02961 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ68@201174,4D10N@85004,COG0186@1,COG0186@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA NIBLCNGB_01191 216816.GS08_09055 4.1e-37 160.2 Bifidobacteriales rpmC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02904 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ6V@201174,4D181@85004,COG0255@1,COG0255@2 NA|NA|NA J Belongs to the universal ribosomal protein uL29 family NIBLCNGB_01192 326426.Bbr_1634 2.2e-75 288.1 Bifidobacteriales rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02878 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFEI@201174,4D0Q8@85004,COG0197@1,COG0197@2 NA|NA|NA J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs NIBLCNGB_01193 326426.Bbr_1635 1.7e-100 372.5 Bifidobacteriales rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02982 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GKF1@201174,4CYQN@85004,COG0092@1,COG0092@2 NA|NA|NA J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation NIBLCNGB_01194 326426.Bbr_1636 5.7e-56 223.4 Bifidobacteriales rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02890 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IM3J@201174,4D0UZ@85004,COG0091@1,COG0091@2 NA|NA|NA J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome NIBLCNGB_01195 1437608.BBIA_2303 3.7e-47 193.7 Bifidobacteriales rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02965 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKMS@201174,4D105@85004,COG0185@1,COG0185@2 NA|NA|NA J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA NIBLCNGB_01196 326426.Bbr_1638 1.8e-153 548.5 Bifidobacteriales rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02886 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GK7R@201174,4CZ5U@85004,COG0090@1,COG0090@2 NA|NA|NA J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity NIBLCNGB_01197 326426.Bbr_1639 7.5e-46 189.5 Bifidobacteriales rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02892 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ7V@201174,4D11N@85004,COG0089@1,COG0089@2 NA|NA|NA J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome NIBLCNGB_01198 326426.Bbr_1640 3.1e-116 424.5 Bifidobacteriales rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02926 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJYJ@201174,4CZSA@85004,COG0088@1,COG0088@2 NA|NA|NA J Forms part of the polypeptide exit tunnel NIBLCNGB_01199 326426.Bbr_1641 8.7e-116 422.9 Bifidobacteriales rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 ko:K02906 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJXT@201174,4CYQD@85004,COG0087@1,COG0087@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit NIBLCNGB_01200 1437600.JDUI01000009_gene364 8e-51 206.1 Bifidobacteriales rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02946 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHRA@201174,4D0UT@85004,COG0051@1,COG0051@2 NA|NA|NA J Involved in the binding of tRNA to the ribosomes NIBLCNGB_01201 216816.GS08_09105 8.2e-137 493.0 Bifidobacteriales budA GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0047605 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 R02948 RC00812 ko00000,ko00001,ko01000 Bacteria 2IBRH@201174,4D0BN@85004,COG3527@1,COG3527@2 NA|NA|NA H Alpha-acetolactate decarboxylase NIBLCNGB_01202 326426.Bbr_1644 9.5e-145 519.6 Bifidobacteriales ywiC Bacteria 28NT3@1,2IIC3@201174,2ZBRV@2,4D0MQ@85004 NA|NA|NA S YwiC-like protein NIBLCNGB_01203 326426.Bbr_1645 0.0 1752.3 Bifidobacteriales adhE 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 iSB619.SA_RS00885 Bacteria 2GJI2@201174,4CZ8F@85004,COG1012@1,COG1012@2,COG1454@1,COG1454@2 NA|NA|NA C belongs to the iron- containing alcohol dehydrogenase family NIBLCNGB_01204 78345.BMERY_0610 3.1e-170 604.4 Bifidobacteriales rhaR_1 Bacteria 2HZE7@201174,4D00U@85004,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein NIBLCNGB_01205 78345.BMERY_0609 1.5e-194 685.3 Bifidobacteriales Z012_01000 1.1.1.14,1.1.1.9 ko:K00008,ko:K05351 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKC7@201174,4D04X@85004,COG1063@1,COG1063@2 NA|NA|NA C Zinc-binding dehydrogenase NIBLCNGB_01206 547043.BIFPSEUDO_02633 2.7e-196 691.4 Bifidobacteriales iYL1228.KPN_02541 Bacteria 2GPRH@201174,4D048@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily NIBLCNGB_01207 78345.BMERY_0607 1.1e-214 752.3 Bifidobacteriales 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2I7R8@201174,4CZZ7@85004,COG1940@1,COG1940@2 NA|NA|NA GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565 NIBLCNGB_01208 78345.BMERY_0606 6e-75 286.6 Bifidobacteriales 4.4.1.5 ko:K01759 ko00620,map00620 R02530 RC00004,RC00740 ko00000,ko00001,ko01000 Bacteria 2IHBC@201174,4D0P3@85004,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NIBLCNGB_01209 78346.BRUM_0709 2.2e-233 814.7 Bifidobacteriales iYL1228.KPN_02541 Bacteria 2GPRH@201174,4D048@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily NIBLCNGB_01210 78345.BMERY_0604 2.3e-179 634.8 Bifidobacteriales tdh 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKC7@201174,4D04X@85004,COG1063@1,COG1063@2 NA|NA|NA C Zinc-binding dehydrogenase NIBLCNGB_01211 547043.BIFPSEUDO_02637 0.0 1694.9 Bifidobacteriales glgX 3.2.1.196,3.2.1.68 ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02111,R09995,R11261 ko00000,ko00001,ko00002,ko01000 CBM48,GH13 Bacteria 2GJ00@201174,4CYZ1@85004,COG1523@1,COG1523@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family NIBLCNGB_01212 216816.GS08_09130 3.7e-82 310.8 Bifidobacteriales rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GNDY@201174,4CZ9Y@85004,COG0103@1,COG0103@2 NA|NA|NA J Belongs to the universal ribosomal protein uS9 family NIBLCNGB_01213 326426.Bbr_1649 3.5e-79 300.8 Bifidobacteriales rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFG1@201174,4D0PV@85004,COG0102@1,COG0102@2 NA|NA|NA J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly NIBLCNGB_01214 326426.Bbr_1650 0.0 1459.5 Bifidobacteriales malQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.4.1.18,2.4.1.25,3.2.1.196,5.4.99.15 ko:K00700,ko:K00705,ko:K02438,ko:K06044 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R01824,R02110,R02111,R05196,R09995 RC00049 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13,GH77 iJN678.malQ Bacteria 2GM5Z@201174,4CZC7@85004,COG1640@1,COG1640@2 NA|NA|NA G 4-alpha-glucanotransferase NIBLCNGB_01215 326426.Bbr_1651 4.2e-116 424.1 Bifidobacteriales Bacteria 2BMRI@1,2GMIA@201174,32GAY@2,4CZFZ@85004 NA|NA|NA NIBLCNGB_01216 326426.Bbr_1652 1.4e-110 405.6 Bifidobacteriales yigZ 2.1.1.45,3.4.13.9 ko:K00560,ko:K01271 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 2GMM4@201174,4CZH8@85004,COG1739@1,COG1739@2 NA|NA|NA S Uncharacterized protein family UPF0029 NIBLCNGB_01217 326426.Bbr_1653 3.8e-182 644.0 Bifidobacteriales MA20_16500 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GKTT@201174,4CZRS@85004,COG0111@1,COG0111@2 NA|NA|NA EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family NIBLCNGB_01218 1437610.BREU_0592 1.8e-117 429.1 Bifidobacteriales ko:K07282 ko00000 Bacteria 2GK15@201174,4D081@85004,COG2843@1,COG2843@2 NA|NA|NA M Bacterial capsule synthesis protein PGA_cap NIBLCNGB_01219 326426.Bbr_1655 6.3e-245 852.8 Bifidobacteriales bglA 3.2.1.21 ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 Bacteria 2GJAF@201174,4CYPX@85004,COG2723@1,COG2723@2 NA|NA|NA G Glycosyl hydrolase family 1 NIBLCNGB_01220 326426.Bbr_1656 6.1e-160 570.1 Bifidobacteriales ko:K02026 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GMTH@201174,4CZQ9@85004,COG0395@1,COG0395@2 NA|NA|NA U Binding-protein-dependent transport system inner membrane component NIBLCNGB_01221 326426.Bbr_1657 1.2e-163 582.4 Bifidobacteriales malC ko:K02025,ko:K10118,ko:K10241,ko:K15771 ko02010,map02010 M00196,M00206,M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.23,3.A.1.1.28 Bacteria 2GKBJ@201174,4CZDV@85004,COG1175@1,COG1175@2 NA|NA|NA U Binding-protein-dependent transport system inner membrane component NIBLCNGB_01222 326426.Bbr_1658 7.1e-242 842.8 Bifidobacteriales malE ko:K02027 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GM4E@201174,4CZ8S@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_01223 326426.Bbr_1659 1.4e-217 761.9 Bifidobacteriales rbsR ko:K02529 ko00000,ko03000 Bacteria 2GJV7@201174,4D04H@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor NIBLCNGB_01224 326426.Bbr_1660 5.2e-22 109.4 Bifidobacteriales Bacteria 2B4WM@1,2GZCV@201174,31XPC@2,4D1TG@85004 NA|NA|NA NIBLCNGB_01226 216816.GS08_09170 3.1e-64 251.1 Bifidobacteriales ko:K11939 ko00000,ko02000 2.A.7.3.6 Bacteria 2GJKB@201174,4D03A@85004,COG5006@1,COG5006@2 NA|NA|NA S EamA-like transporter family NIBLCNGB_01227 216816.GS08_09170 3.9e-21 107.1 Bifidobacteriales ko:K11939 ko00000,ko02000 2.A.7.3.6 Bacteria 2GJKB@201174,4D03A@85004,COG5006@1,COG5006@2 NA|NA|NA S EamA-like transporter family NIBLCNGB_01228 326426.Bbr_1662 6.5e-235 819.7 Bifidobacteriales dinB 2.7.7.7 ko:K02346 ko00000,ko01000,ko03400 Bacteria 2GKBI@201174,4CZHT@85004,COG0389@1,COG0389@2 NA|NA|NA L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII NIBLCNGB_01229 326426.Bbr_1663 4.4e-222 776.9 Bifidobacteriales dapC Bacteria 2GJMI@201174,4CZ91@85004,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase class I and II NIBLCNGB_01230 326426.Bbr_1664 8.3e-59 232.6 Bifidobacteriales fdxA ko:K05524 ko00000 Bacteria 2IKVN@201174,4D11B@85004,COG1146@1,COG1146@2 NA|NA|NA C 4Fe-4S binding domain NIBLCNGB_01231 326426.Bbr_1665 1.5e-267 928.3 Bifidobacteriales ko:K03294 ko00000 2.A.3.2 Bacteria 2GJ75@201174,4CYZA@85004,COG0531@1,COG0531@2 NA|NA|NA E aromatic amino acid transport protein AroP K03293 NIBLCNGB_01232 326426.Bbr_1666 1.8e-215 755.0 Bifidobacteriales murB GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0022603,GO:0022604,GO:0030203,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0055114,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 iECED1_1282.ECED1_4683,iECUMN_1333.ECUMN_4498_AT6,iLF82_1304.LF82_1416,iNRG857_1313.NRG857_19845 Bacteria 2GIV2@201174,4CZSJ@85004,COG0812@1,COG0812@2 NA|NA|NA M Cell wall formation NIBLCNGB_01233 1437609.BCAL_1264 4.1e-25 119.8 Bifidobacteriales rpmG ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQFG@201174,4D1EA@85004,COG0267@1,COG0267@2 NA|NA|NA J Ribosomal protein L33 NIBLCNGB_01237 326426.Bbr_1668 1.5e-46 191.8 Bifidobacteriales groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K04078 ko00000,ko03029,ko03110 Bacteria 2IKTH@201174,4D101@85004,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter NIBLCNGB_01238 326426.Bbr_1669 1.1e-135 490.0 Bifidobacteriales Bacteria 2E03N@1,2GQE4@201174,32VSG@2,4CYUX@85004 NA|NA|NA NIBLCNGB_01239 326426.Bbr_1670 2.6e-85 321.2 Bifidobacteriales rimJ 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 2HAFI@201174,4CZRR@85004,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain NIBLCNGB_01240 1437610.BREU_0576 1.1e-55 223.4 Bifidobacteriales fthC 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 Bacteria 2IKWR@201174,4D12B@85004,COG0212@1,COG0212@2 NA|NA|NA H 5-formyltetrahydrofolate cyclo-ligase family NIBLCNGB_01241 326426.Bbr_1670a 4.3e-31 139.8 Bifidobacteriales fmdB Bacteria 2IQHE@201174,4D1ES@85004,COG2331@1,COG2331@2 NA|NA|NA S Putative regulatory protein NIBLCNGB_01242 326426.Bbr_1672 7e-93 346.7 Bifidobacteriales flgA GO:0001539,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 ko:K02279,ko:K02386 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Bacteria 2IIYF@201174,4D0YD@85004,COG1261@1,COG1261@2 NA|NA|NA NO SAF NIBLCNGB_01243 1437610.BREU_0572 6.6e-19 99.0 Bifidobacteriales Bacteria 2GKJW@201174,4CYY9@85004,COG1112@1,COG1112@2 NA|NA|NA L Superfamily I DNA and RNA helicases and helicase subunits NIBLCNGB_01244 326426.Bbr_1673 0.0 2325.8 Bifidobacteriales Bacteria 2GKJW@201174,4CYY9@85004,COG1112@1,COG1112@2 NA|NA|NA L Superfamily I DNA and RNA helicases and helicase subunits NIBLCNGB_01245 326426.Bbr_1674 1.1e-184 652.9 Bifidobacteriales Bacteria 2GIT6@201174,4CYX9@85004,COG1716@1,COG1716@2 NA|NA|NA T Forkhead associated domain NIBLCNGB_01246 326426.Bbr_1675 9.3e-49 199.5 Bifidobacteriales rplL GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKNW@201174,4D0W2@85004,COG0222@1,COG0222@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation NIBLCNGB_01247 326426.Bbr_1676 2.4e-87 328.2 Bifidobacteriales rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GM0V@201174,4CZFP@85004,COG0244@1,COG0244@2 NA|NA|NA J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors NIBLCNGB_01248 326426.Bbr_1677 7.1e-144 516.5 Bifidobacteriales 3.2.1.8 ko:K01181,ko:K06889 ko00000,ko01000 Bacteria 2HZF3@201174,4D06X@85004,COG1073@1,COG1073@2 NA|NA|NA S alpha beta NIBLCNGB_01249 326426.Bbr_1678 1.1e-251 875.5 Bifidobacteriales pbuO ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 2GKYD@201174,4CZHD@85004,COG2252@1,COG2252@2 NA|NA|NA S Permease family NIBLCNGB_01250 326426.Bbr_1679 1.2e-148 532.3 Bifidobacteriales pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 Bacteria 2GJQ3@201174,4CYVE@85004,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system NIBLCNGB_01251 326426.Bbr_1680 1.3e-171 609.0 Bifidobacteriales pstA GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0033554,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 ko:K02037,ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 iJN746.PP_2658,iPC815.YPO4115,iYL1228.KPN_04131,iZ_1308.Z5217 Bacteria 2I2F2@201174,4D2UW@85004,COG0581@1,COG0581@2 NA|NA|NA P Phosphate transport system permease NIBLCNGB_01252 326426.Bbr_1681 3.4e-156 557.8 Bifidobacteriales pstC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0009314,GO:0009628,GO:0010921,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 ko:K02037,ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 iAF987.Gmet_2702,ic_1306.c4652 Bacteria 2GJDA@201174,4CYV0@85004,COG0573@1,COG0573@2 NA|NA|NA P probably responsible for the translocation of the substrate across the membrane NIBLCNGB_01253 326426.Bbr_1682 2.8e-202 711.1 Bifidobacteriales pstS ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 2GJXD@201174,4CYTZ@85004,COG0226@1,COG0226@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import NIBLCNGB_01254 326426.Bbr_1683 3.8e-142 510.8 Bifidobacteriales Bacteria 2GKFS@201174,4CZTX@85004,COG0745@1,COG0745@2 NA|NA|NA KT Transcriptional regulatory protein, C terminal NIBLCNGB_01255 326426.Bbr_1684 3.2e-205 721.1 Bifidobacteriales senX3 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564 2.7.13.3 ko:K07636,ko:K07768,ko:K11383 ko02020,map02020 M00434,M00443,M00505 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2GJY7@201174,4CZ42@85004,COG5002@1,COG5002@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain NIBLCNGB_01256 326426.Bbr_1685 8.1e-58 229.6 Bifidobacteriales ko:K03762 ko00000,ko02000 2.A.1.6.4 Bacteria 2GIYR@201174,4CZFF@85004,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter NIBLCNGB_01257 326426.Bbr_1685 1e-168 599.4 Bifidobacteriales ko:K03762 ko00000,ko02000 2.A.1.6.4 Bacteria 2GIYR@201174,4CZFF@85004,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter NIBLCNGB_01258 326426.Bbr_1686 3.7e-123 447.6 Bifidobacteriales mtnN 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 Bacteria 2I8GZ@201174,4CYTM@85004,COG0775@1,COG0775@2 NA|NA|NA E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively NIBLCNGB_01259 326426.Bbr_1687 4.7e-235 820.1 Bifidobacteriales aroG GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2375,iAPECO1_1312.APECO1_3932,iECNA114_1301.ECNA114_0684,iECOK1_1307.ECOK1_2946,iECS88_1305.ECS88_2787,iECSF_1327.ECSF_0680,iEcSMS35_1347.EcSMS35_0777,iHN637.CLJU_RS07240,iLF82_1304.LF82_0146,iNRG857_1313.NRG857_03335,iSbBS512_1146.SbBS512_E1908,iUMN146_1321.UM146_03705,iUTI89_1310.UTI89_C2934,iYL1228.KPN_00758 Bacteria 2GMVF@201174,4CZ7I@85004,COG0722@1,COG0722@2 NA|NA|NA E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) NIBLCNGB_01260 326426.Bbr_1688 1.5e-216 758.4 Bifidobacteriales aroG GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2375,iAPECO1_1312.APECO1_3932,iECNA114_1301.ECNA114_0684,iECOK1_1307.ECOK1_2946,iECS88_1305.ECS88_2787,iECSF_1327.ECSF_0680,iEcSMS35_1347.EcSMS35_0777,iHN637.CLJU_RS07240,iLF82_1304.LF82_0146,iNRG857_1313.NRG857_03335,iSbBS512_1146.SbBS512_E1908,iUMN146_1321.UM146_03705,iUTI89_1310.UTI89_C2934,iYL1228.KPN_00758 Bacteria 2GMVF@201174,4CZMR@85004,COG0722@1,COG0722@2 NA|NA|NA E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) NIBLCNGB_01261 326426.Bbr_1700 1e-267 928.7 Bifidobacteriales pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 2GNYU@201174,4CZDZ@85004,COG3579@1,COG3579@2 NA|NA|NA E Peptidase C1-like family NIBLCNGB_01262 326426.Bbr_1701 3.6e-45 189.5 Bifidobacteriales Bacteria 2HZ99@201174,4CZ0S@85004,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation NIBLCNGB_01263 326426.Bbr_1702 2.6e-126 458.0 Bifidobacteriales pcp GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 ko:K01304 ko00000,ko01000,ko01002 Bacteria 2GN39@201174,4CZ57@85004,COG2039@1,COG2039@2 NA|NA|NA O Removes 5-oxoproline from various penultimate amino acid residues except L-proline NIBLCNGB_01264 326426.Bbr_1703 8.4e-151 539.7 Bifidobacteriales ispD GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.405,2.7.7.40,2.7.7.60,4.6.1.12 ko:K00991,ko:K12506,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 M00096 R01525,R02921,R05633,R05637 RC00002,RC00089,RC01440 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNHP@201174,4CYVZ@85004,COG1211@1,COG1211@2 NA|NA|NA I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) NIBLCNGB_01265 326426.Bbr_1704 8e-199 699.5 Bifidobacteriales yfiH GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944 ko:K05810 ko00000,ko01000 Bacteria 2GN1M@201174,4CZBI@85004,COG1496@1,COG1496@2 NA|NA|NA Q Multi-copper polyphenol oxidoreductase laccase NIBLCNGB_01266 326426.Bbr_1705 1e-303 1048.5 Bifidobacteriales yegQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Bacteria 2GKTB@201174,4CZA1@85004,COG0826@1,COG0826@2 NA|NA|NA O Peptidase family U32 C-terminal domain NIBLCNGB_01267 326426.Bbr_1706 1.4e-178 632.1 Bifidobacteriales trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 2GJ1G@201174,4CZ7A@85004,COG0336@1,COG0336@2 NA|NA|NA J Belongs to the RNA methyltransferase TrmD family NIBLCNGB_01268 326426.Bbr_1707 7.7e-103 379.8 Bifidobacteriales rsmD 2.1.1.171 ko:K08316 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 2GQ3G@201174,4D0GU@85004,COG0742@1,COG0742@2 NA|NA|NA L Conserved hypothetical protein 95 NIBLCNGB_01269 326426.Bbr_1708 0.0 1595.1 Bifidobacteriales recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKA3@201174,4CYTV@85004,COG1200@1,COG1200@2 NA|NA|NA L helicase superfamily c-terminal domain NIBLCNGB_01270 326426.Bbr_1709 2.5e-29 134.0 Bifidobacteriales rpmB GO:0003674,GO:0003735,GO:0005198 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQNU@201174,4D17Q@85004,COG0227@1,COG0227@2 NA|NA|NA J Ribosomal L28 family NIBLCNGB_01271 326426.Bbr_1710 3.2e-197 694.1 Bifidobacteriales yegV GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 Bacteria 2IA3T@201174,4CYSM@85004,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase NIBLCNGB_01272 326426.Bbr_1711 2.5e-239 834.3 Bifidobacteriales yxiO ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 Bacteria 2GJCW@201174,4CZU3@85004,COG2270@1,COG2270@2 NA|NA|NA S Vacuole effluxer Atg22 like NIBLCNGB_01273 326426.Bbr_1712 3.7e-82 310.8 Bifidobacteriales soxR ko:K13639 ko00000,ko03000 Bacteria 2HZI3@201174,4D0I1@85004,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance NIBLCNGB_01274 216816.GS08_01645 6.5e-60 236.5 Bifidobacteriales Bacteria 2IFQF@201174,4D0PF@85004,COG2337@1,COG2337@2 NA|NA|NA T Toxic component of a toxin-antitoxin (TA) module NIBLCNGB_01275 216816.GS08_01640 9e-53 212.6 Bifidobacteriales relB ko:K07473 ko00000,ko02048 Bacteria 2IJU2@201174,4D0WU@85004,COG3077@1,COG3077@2 NA|NA|NA L RelB antitoxin NIBLCNGB_01276 216816.GS08_01635 6.1e-25 119.4 Bacteria yxiO ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 Bacteria COG2270@1,COG2270@2 NA|NA|NA G Major facilitator Superfamily NIBLCNGB_01277 216816.GS08_01630 1.7e-188 665.2 Bifidobacteriales Bacteria 2IBHI@201174,4CZ2T@85004,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins NIBLCNGB_01278 326426.Bbr_1717 3.4e-63 247.7 Actinobacteria Bacteria 2DQJC@1,2I5YK@201174,33782@2 NA|NA|NA S Alpha/beta hydrolase family NIBLCNGB_01282 1437600.JDUI01000007_gene840 9.4e-17 92.4 Bifidobacteriales Bacteria 2I8HS@201174,4CZ4M@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily NIBLCNGB_01283 1437610.BREU_0523 6.1e-45 186.8 Bifidobacteriales XK27_04590 ko:K19784 ko00000 Bacteria 2GMA7@201174,4D163@85004,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase NIBLCNGB_01285 326426.Bbr_1720 4.2e-300 1036.6 Bifidobacteriales pccB Bacteria 2GIRU@201174,4CYSI@85004,COG4799@1,COG4799@2 NA|NA|NA I Carboxyl transferase domain NIBLCNGB_01286 326426.Bbr_1721 0.0 1215.7 Bifidobacteriales accA 6.3.4.14,6.4.1.2,6.4.1.3 ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00741 R00742,R01859,R04385 RC00040,RC00097,RC00253,RC00367,RC00609 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIZP@201174,4CYU4@85004,COG4770@1,COG4770@2 NA|NA|NA I Carbamoyl-phosphate synthase L chain, ATP binding domain protein NIBLCNGB_01287 326426.Bbr_1722 2.2e-92 345.1 Bifidobacteriales bioY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03523 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 Bacteria 2GJ53@201174,4D0BB@85004,COG1268@1,COG1268@2 NA|NA|NA S BioY family NIBLCNGB_01288 326426.Bbr_1723 2.2e-163 581.6 Bifidobacteriales birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 2.7.1.33,6.3.4.15 ko:K01947,ko:K03524 ko00770,ko00780,ko01100,map00770,map00780,map01100 M00120 R01074,R02971,R03018,R04391,R05145 RC00002,RC00017,RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 2GN8Q@201174,4D0R8@85004,COG0340@1,COG0340@2 NA|NA|NA H Biotin/lipoate A/B protein ligase family NIBLCNGB_01289 326426.Bbr_1724 0.0 1345.5 Bifidobacteriales Bacteria 2DX0J@1,2H683@201174,342TV@2,4CZAG@85004 NA|NA|NA NIBLCNGB_01290 326426.Bbr_1725 1.4e-164 585.5 Bifidobacteriales Bacteria 2GN0S@201174,4CYXU@85004,COG2508@1,COG2508@2 NA|NA|NA QT PucR C-terminal helix-turn-helix domain NIBLCNGB_01291 326426.Bbr_1726 2.7e-123 448.0 Bifidobacteriales rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GM51@201174,4CZFR@85004,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release NIBLCNGB_01292 216816.GS08_09450 1e-72 279.3 Bifidobacteriales rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFCK@201174,4D0PA@85004,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors NIBLCNGB_01293 326426.Bbr_1728 2.5e-146 524.6 Bifidobacteriales Bacteria 2IDUY@201174,4D00E@85004,COG5340@1,COG5340@2 NA|NA|NA K Psort location Cytoplasmic, score NIBLCNGB_01294 326426.Bbr_1729 7e-110 403.7 Bifidobacteriales nusG GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 2GJFW@201174,4CYSH@85004,COG0250@1,COG0250@2 NA|NA|NA K Participates in transcription elongation, termination and antitermination NIBLCNGB_01295 326426.Bbr_1730 5.6e-33 146.4 Bifidobacteriales secE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2HZQC@201174,4D18K@85004,COG0690@1,COG0690@2 NA|NA|NA U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation NIBLCNGB_01297 326426.Bbr_1731 7.6e-230 802.7 Bifidobacteriales aspC Bacteria 2GJ7R@201174,4CZFY@85004,COG0436@1,COG0436@2 NA|NA|NA E DegT/DnrJ/EryC1/StrS aminotransferase family NIBLCNGB_01298 326426.Bbr_1732 4.7e-214 750.4 Bacteria Bacteria COG0726@1,COG0726@2 NA|NA|NA G polysaccharide deacetylase NIBLCNGB_01299 326426.Bbr_1733 8.3e-199 699.5 Bifidobacteriales proB GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM8U@201174,4CZ2B@85004,COG0263@1,COG0263@2 NA|NA|NA E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate NIBLCNGB_01300 326426.Bbr_1734 6.1e-310 1069.3 Bifidobacteriales obg GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904 ko:K03979 ko00000,ko01000,ko03009 Bacteria 2GISB@201174,4CYWD@85004,COG0536@1,COG0536@2 NA|NA|NA S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control NIBLCNGB_01301 326426.Bbr_1735 5.8e-39 166.4 Bifidobacteriales rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQDI@201174,4D19N@85004,COG0211@1,COG0211@2 NA|NA|NA J Ribosomal L27 protein NIBLCNGB_01302 326426.Bbr_1736 1.4e-47 195.3 Bifidobacteriales rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ9A@201174,4D10B@85004,COG0261@1,COG0261@2 NA|NA|NA J This protein binds to 23S rRNA in the presence of protein L20 NIBLCNGB_01303 326426.Bbr_1737 0.0 1166.0 Bifidobacteriales rne GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 3.1.26.12 ko:K08300,ko:K08301 ko03018,map03018 M00394 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Bacteria 2GMM5@201174,4CYQT@85004,COG1530@1,COG1530@2 NA|NA|NA J Ribonuclease E/G family NIBLCNGB_01304 326426.Bbr_1738 1.8e-231 808.1 Bifidobacteriales dapE 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK09@201174,4CZ9K@85004,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain NIBLCNGB_01305 326426.Bbr_1739 1.9e-167 595.1 Bifidobacteriales mdcF ko:K07088 ko00000 Bacteria 2GNIA@201174,4CZFX@85004,COG0679@1,COG0679@2 NA|NA|NA S Transporter, auxin efflux carrier (AEC) family protein NIBLCNGB_01306 326426.Bbr_1740 5.7e-166 590.1 Bifidobacteriales dapA 4.1.2.28,4.3.3.7 ko:K01714,ko:K22397 ko00040,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00040,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R01782,R10147 RC00307,RC00572,RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJDB@201174,4D04B@85004,COG0329@1,COG0329@2 NA|NA|NA EM Dihydrodipicolinate synthetase family NIBLCNGB_01307 326426.Bbr_1741 3.2e-149 534.3 Bifidobacteriales ko:K07046 ko00051,ko01120,map00051,map01120 R10689 RC00537 ko00000,ko00001,ko01000 Bacteria 2HRH9@201174,4CZX0@85004,COG3618@1,COG3618@2 NA|NA|NA S Amidohydrolase NIBLCNGB_01308 216816.GS08_09520 2.7e-201 708.0 Bifidobacteriales fucP ko:K02429 ko00000,ko02000 2.A.1.7 Bacteria 2GJ5D@201174,4D02K@85004,COG0738@1,COG0738@2 NA|NA|NA G Major Facilitator Superfamily NIBLCNGB_01309 216816.GS08_09525 2.8e-148 531.2 Bifidobacteriales Bacteria 2GJGM@201174,4CZXI@85004,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain NIBLCNGB_01310 326426.Bbr_1744 1.1e-250 872.1 Bifidobacteriales 4.2.1.68 ko:K18334 ko00051,ko01120,map00051,map01120 R03688 RC00543 ko00000,ko00001,ko01000 Bacteria 2GKSK@201174,4D0EI@85004,COG4948@1,COG4948@2 NA|NA|NA M Enolase C-terminal domain-like NIBLCNGB_01311 326426.Bbr_1745 1.2e-191 675.6 Bifidobacteriales ko:K02529,ko:K17640 ko00000,ko03000 Bacteria 2GJRG@201174,4CZI0@85004,COG1609@1,COG1609@2 NA|NA|NA K Bacterial regulatory proteins, lacI family NIBLCNGB_01312 216816.GS08_09540 1.4e-222 778.9 Bifidobacteriales ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GKF3@201174,4D03X@85004,COG0577@1,COG0577@2 NA|NA|NA V Efflux ABC transporter, permease protein NIBLCNGB_01313 326426.Bbr_1747 1.6e-130 472.2 Bifidobacteriales ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GM25@201174,4D0FV@85004,COG1136@1,COG1136@2 NA|NA|NA V ATPases associated with a variety of cellular activities NIBLCNGB_01314 1437608.BBIA_1347 7.2e-29 133.3 Bifidobacteriales Bacteria 2B12Y@1,2GWJ2@201174,30DWC@2,4D1TU@85004 NA|NA|NA S Protein of unknown function (DUF1778) NIBLCNGB_01315 326426.Bbr_1748 5.5e-89 333.6 Bifidobacteriales Bacteria 2IC6K@201174,4D0SR@85004,COG0454@1,COG0454@2 NA|NA|NA K Acetyltransferase (GNAT) family NIBLCNGB_01316 326426.Bbr_1749 3.9e-273 946.8 Bifidobacteriales maf GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 1.1.1.25,2.1.1.190,3.6.1.55,3.6.1.67 ko:K00014,ko:K03215,ko:K03574,ko:K06287,ko:K08310 ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230 M00022,M00126 R02413,R04638 RC00002,RC00206 ko00000,ko00001,ko00002,ko01000,ko03009,ko03400 Bacteria 2GNI0@201174,4CZXF@85004,COG0424@1,COG0424@2,COG1051@1,COG1051@2 NA|NA|NA DF Maf-like protein NIBLCNGB_01317 216816.GS08_09565 9.3e-185 652.9 Bifidobacteriales thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545,iSB619.SA_RS06620 Bacteria 2GKIW@201174,4CZN0@85004,COG0083@1,COG0083@2 NA|NA|NA E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate NIBLCNGB_01318 326426.Bbr_1751 1.8e-237 828.2 Bifidobacteriales hom GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1294,iSB619.SA_RS06610 Bacteria 2GIX9@201174,4CZVD@85004,COG0460@1,COG0460@2 NA|NA|NA E Homoserine dehydrogenase NIBLCNGB_01319 1437608.BBIA_0273 3.3e-54 218.0 Bifidobacteriales nagE 2.7.1.193,2.7.1.199 ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 M00267,M00809 R02738,R05199 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.13,4.A.1.1.14,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.1.9 iSB619.SA_RS08720 Bacteria 2GKPM@201174,4D069@85004,COG1263@1,COG1263@2,COG1264@1,COG1264@2 NA|NA|NA G phosphotransferase system, EIIB NIBLCNGB_01320 702459.BBPR_0239 1.4e-55 222.6 Bifidobacteriales 2.7.1.208 ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12 Bacteria 2INQB@201174,4D11R@85004,COG2190@1,COG2190@2 NA|NA|NA G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 NIBLCNGB_01321 326426.Bbr_1753 1.8e-303 1047.7 Bifidobacteriales lysA 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKAI@201174,4CYRG@85004,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine NIBLCNGB_01322 326426.Bbr_1754 0.0 1216.4 Bifidobacteriales argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iAF987.Gmet_1434 Bacteria 2GKQ3@201174,4CZ9J@85004,COG0018@1,COG0018@2 NA|NA|NA J Arginyl-tRNA synthetase NIBLCNGB_01323 326426.Bbr_1755 8.1e-131 473.0 Bifidobacteriales Bacteria 2HZJX@201174,4D0QJ@85004,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family NIBLCNGB_01324 326426.Bbr_1756 3.6e-222 777.3 Bifidobacteriales Bacteria 2HZ9S@201174,4CZ4Z@85004,COG2271@1,COG2271@2 NA|NA|NA G Transmembrane secretion effector NIBLCNGB_01325 326426.Bbr_1757 6.8e-256 889.4 Bifidobacteriales murA 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 Bacteria 2GJPW@201174,4CZN7@85004,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine NIBLCNGB_01326 326426.Bbr_1758 1.2e-200 705.7 Bifidobacteriales nox 1.6.3.4 ko:K17869 ko00000,ko01000 Bacteria 2H7WY@201174,4CZXP@85004,COG0446@1,COG0446@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase NIBLCNGB_01327 1203566.HMPREF1285_01136 8.4e-128 463.0 Corynebacteriaceae ksgA 2.1.1.182,2.1.1.184 ko:K00561,ko:K02528 R10716 RC00003,RC03257 br01600,ko00000,ko01000,ko01504,ko03009 Bacteria 22JXN@1653,2H1TK@201174,COG0030@1,COG0030@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family NIBLCNGB_01328 504474.cu1923 4.4e-111 407.1 Bacteria Bacteria COG3464@1,COG3464@2 NA|NA|NA NIBLCNGB_01329 1203567.HMPREF1286_00566 3e-228 797.3 Corynebacteriaceae 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 22KBK@1653,2IEJD@201174,COG3677@1,COG3677@2 NA|NA|NA L Transposase and inactivated derivatives NIBLCNGB_01330 1203566.HMPREF1285_01136 1.2e-157 562.4 Corynebacteriaceae ksgA 2.1.1.182,2.1.1.184 ko:K00561,ko:K02528 R10716 RC00003,RC03257 br01600,ko00000,ko01000,ko01504,ko03009 Bacteria 22JXN@1653,2H1TK@201174,COG0030@1,COG0030@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family NIBLCNGB_01331 504474.cu1923 4.4e-111 407.1 Bacteria Bacteria COG3464@1,COG3464@2 NA|NA|NA NIBLCNGB_01332 1203567.HMPREF1286_00566 3e-228 797.3 Corynebacteriaceae 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 22KBK@1653,2IEJD@201174,COG3677@1,COG3677@2 NA|NA|NA L Transposase and inactivated derivatives NIBLCNGB_01333 216816.GS08_09600 3.9e-37 160.2 Bifidobacteriales nox 1.6.3.4 ko:K17869 ko00000,ko01000 Bacteria 2H7WY@201174,4CZXP@85004,COG0446@1,COG0446@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase NIBLCNGB_01334 216816.GS08_09605 2.4e-209 734.6 Bifidobacteriales pyrD 1.3.1.14,1.3.98.1 ko:K00226,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJMN@201174,4CZKM@85004,COG0167@1,COG0167@2 NA|NA|NA F Dihydroorotate dehydrogenase NIBLCNGB_01335 326426.Bbr_1766 1.8e-130 471.9 Bifidobacteriales leuD GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2987c Bacteria 2GJ8Z@201174,4CZ2F@85004,COG0066@1,COG0066@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate NIBLCNGB_01336 216816.GS08_09615 2.7e-271 940.6 Bifidobacteriales leuC GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 iEcE24377_1341.EcE24377A_0075,iPC815.YPO0531 Bacteria 2GKT7@201174,4CYUC@85004,COG0065@1,COG0065@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate NIBLCNGB_01337 216816.GS08_09620 4.5e-138 497.3 Bifidobacteriales ltbR Bacteria 2GKB0@201174,4CZ9D@85004,COG1414@1,COG1414@2 NA|NA|NA K Transcriptional regulator, IclR family, C-terminal domain protein NIBLCNGB_01338 216816.GS08_09625 1.8e-242 844.7 Bifidobacteriales Bacteria 2HRDZ@201174,4CYQR@85004,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase NIBLCNGB_01339 216816.GS08_09630 0.0 1467.6 Bifidobacteriales ppk 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2GJ0B@201174,4CYXH@85004,COG0855@1,COG0855@2 NA|NA|NA P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) NIBLCNGB_01340 326426.Bbr_1771 1.2e-229 802.4 Bifidobacteriales mutT 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574,ko:K08296 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 2GNRV@201174,4CZ90@85004,COG0494@1,COG0494@2,COG2062@1,COG2062@2 NA|NA|NA LT Phosphoglycerate mutase family NIBLCNGB_01341 326426.Bbr_1772 2.1e-130 471.9 Bifidobacteriales Bacteria 28MMU@1,2HAD5@201174,2ZAXG@2,4CZ1Q@85004 NA|NA|NA NIBLCNGB_01342 326426.Bbr_1775 0.0 1271.1 Bifidobacteriales Bacteria 2GIUI@201174,4D0HI@85004,COG3408@1,COG3408@2 NA|NA|NA G N-terminal domain of (some) glycogen debranching enzymes NIBLCNGB_01343 326426.Bbr_1776 4.6e-49 200.3 Bifidobacteriales ko:K02026 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GITV@201174,4CZHG@85004,COG0395@1,COG0395@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component NIBLCNGB_01344 326426.Bbr_1777 3.9e-116 424.1 Bifidobacteriales upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000 Bacteria 2GPJE@201174,4CYVS@85004,COG0035@1,COG0035@2 NA|NA|NA F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate NIBLCNGB_01345 216816.GS08_09655 2.8e-82 311.2 Bifidobacteriales rlmH 2.1.1.177 ko:K00783 ko00000,ko01000,ko03009 Bacteria 2IJE0@201174,4D0P5@85004,COG1576@1,COG1576@2 NA|NA|NA J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA NIBLCNGB_01346 326426.Bbr_1779 1.3e-215 755.4 Bifidobacteriales ugpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 2GNM5@201174,4CYS4@85004,COG0584@1,COG0584@2 NA|NA|NA C Glycerophosphoryl diester phosphodiesterase family NIBLCNGB_01347 326426.Bbr_1780 2.7e-218 764.2 Bifidobacteriales gluQ 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Bacteria 2GKMT@201174,4CYRY@85004,COG0008@1,COG0008@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family NIBLCNGB_01349 326426.Bbr_1781 0.0 1650.6 Bifidobacteriales clpB GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K03694,ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Bacteria 2GJ73@201174,4CZDY@85004,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE NIBLCNGB_01350 326426.Bbr_1782 1e-165 589.3 Bifidobacteriales ko:K07088 ko00000 Bacteria 2GN0R@201174,4CZ6C@85004,COG0679@1,COG0679@2 NA|NA|NA S Auxin Efflux Carrier NIBLCNGB_01351 326426.Bbr_1783 1.7e-156 558.5 Bifidobacteriales fahA Bacteria 2GN2G@201174,4CZH5@85004,COG0179@1,COG0179@2 NA|NA|NA Q Fumarylacetoacetate (FAA) hydrolase family NIBLCNGB_01352 326426.Bbr_1784 3.6e-110 404.4 Bifidobacteriales Bacteria 2EGCD@1,2I2HS@201174,33A46@2,4D1EH@85004 NA|NA|NA S Domain of unknown function (DUF4190) NIBLCNGB_01353 326426.Bbr_1785 1.3e-165 589.0 Bifidobacteriales Bacteria 2BG3R@1,2IR5J@201174,32A0B@2,4D1AV@85004 NA|NA|NA NIBLCNGB_01354 326426.Bbr_1786 5e-234 816.6 Bifidobacteriales glf GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0071554,GO:0071766,GO:0071840,GO:0071944,GO:0097159,GO:1901265,GO:1901363 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 iNJ661.Rv3809c Bacteria 2GK2Z@201174,4CZ2W@85004,COG0562@1,COG0562@2 NA|NA|NA M UDP-galactopyranose mutase NIBLCNGB_01355 1437610.BREU_1204 8.2e-64 250.0 Bifidobacteriales Bacteria 2IQFY@201174,4D15C@85004,COG3311@1,COG3311@2 NA|NA|NA K Helix-turn-helix domain NIBLCNGB_01356 1437608.BBIA_2250 4.8e-07 60.1 Bifidobacteriales Bacteria 2IMP1@201174,4D13G@85004,COG1569@1,COG1569@2 NA|NA|NA S PIN domain NIBLCNGB_01357 566552.BIFCAT_01196 8e-29 133.3 Bifidobacteriales Bacteria 2GW1R@201174,4D1HV@85004,COG3415@1,COG3415@2 NA|NA|NA L Transposase NIBLCNGB_01358 702459.BBPR_0058 3.1e-32 144.1 Bifidobacteriales Bacteria 2GKW1@201174,4D05P@85004,COG2801@1,COG2801@2 NA|NA|NA L PFAM Integrase catalytic NIBLCNGB_01359 428125.CLOLEP_00679 1.3e-46 193.0 Ruminococcaceae 5.3.1.27 ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05339,R09780 RC00377 ko00000,ko00001,ko00002,ko01000 Bacteria 1UYG2@1239,25A7T@186801,3WRAW@541000,COG0794@1,COG0794@2 NA|NA|NA G sugar phosphate isomerase involved in capsule formation NIBLCNGB_01360 411468.CLOSCI_01968 1.9e-57 229.9 Lachnoclostridium Bacteria 1V3BR@1239,220P8@1506553,249XT@186801,COG1172@1,COG1172@2 NA|NA|NA G Branched-chain amino acid transport system / permease component NIBLCNGB_01361 592026.GCWU0000282_002492 1.9e-72 279.6 Clostridia ko:K02057 M00221 ko00000,ko00002,ko02000 3.A.1.2 Bacteria 1V20A@1239,247TN@186801,COG1172@1,COG1172@2 NA|NA|NA P branched-chain amino acid ABC transporter, permease protein NIBLCNGB_01362 411468.CLOSCI_01966 1.4e-119 436.8 Lachnoclostridium Bacteria 1TP6I@1239,21Z5E@1506553,24CJF@186801,COG1129@1,COG1129@2 NA|NA|NA G ATPases associated with a variety of cellular activities NIBLCNGB_01363 1122962.AULH01000016_gene124 2.1e-79 302.8 Alphaproteobacteria ko:K10559 ko02010,map02010 M00220 ko00000,ko00001,ko00002,ko02000 3.A.1.2.9 Bacteria 1MUAT@1224,2U2VQ@28211,COG1879@1,COG1879@2 NA|NA|NA G ABC-type sugar transport system periplasmic component NIBLCNGB_01364 585198.HMPREF0574_1384 3e-167 595.1 Actinobacteria xylB 1.1.1.57,2.7.1.17 ko:K00040,ko:K00854,ko:K19168 ko00040,ko01100,map00040,map01100 M00014,M00061 R01639,R02454 RC00002,RC00085,RC00538 ko00000,ko00001,ko00002,ko01000,ko02048 Bacteria 2GJDZ@201174,4D3F4@85005,COG1070@1,COG1070@2 NA|NA|NA G Belongs to the FGGY kinase family NIBLCNGB_01365 548479.HMPREF0573_10533 1e-75 290.8 Actinobacteria xylR Bacteria 2GJIE@201174,4D4U2@85005,COG1940@1,COG1940@2 NA|NA|NA GK ROK family NIBLCNGB_01366 326426.Bbr_1785 8.3e-65 254.2 Bifidobacteriales Bacteria 2BG3R@1,2IR5J@201174,32A0B@2,4D1AV@85004 NA|NA|NA NIBLCNGB_01367 702459.BBPR_0072 1.6e-191 675.2 Bifidobacteriales Bacteria 2I2H4@201174,4CYWJ@85004,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 NIBLCNGB_01368 326426.Bbr_1790 2.9e-48 198.4 Bifidobacteriales XK27_08315 Bacteria 2HVID@201174,4CZ6J@85004,COG1368@1,COG1368@2 NA|NA|NA M Psort location CytoplasmicMembrane, score 9.26 NIBLCNGB_01369 326426.Bbr_1790 2.3e-52 211.5 Bifidobacteriales XK27_08315 Bacteria 2HVID@201174,4CZ6J@85004,COG1368@1,COG1368@2 NA|NA|NA M Psort location CytoplasmicMembrane, score 9.26 NIBLCNGB_01370 326426.Bbr_0312 3.8e-219 767.3 Bifidobacteriales Bacteria 2GM8F@201174,4D01G@85004,COG3328@1,COG3328@2 NA|NA|NA L Transposase, Mutator family NIBLCNGB_01371 326426.Bbr_1790 1.6e-111 409.1 Bifidobacteriales XK27_08315 Bacteria 2HVID@201174,4CZ6J@85004,COG1368@1,COG1368@2 NA|NA|NA M Psort location CytoplasmicMembrane, score 9.26 NIBLCNGB_01372 762211.BSTEL_1629 6.9e-64 251.5 Bifidobacteriales Bacteria 2IAIH@201174,4D08G@85004,COG4713@1,COG4713@2 NA|NA|NA S Predicted membrane protein (DUF2142) NIBLCNGB_01373 1437610.BREU_1897 7.7e-152 543.5 Bifidobacteriales Bacteria 2GKW1@201174,4D05P@85004,COG2801@1,COG2801@2,COG3415@1,COG3415@2 NA|NA|NA L PFAM Integrase catalytic NIBLCNGB_01374 1437610.BREU_1897 4.3e-42 176.8 Bifidobacteriales Bacteria 2GKW1@201174,4D05P@85004,COG2801@1,COG2801@2,COG3415@1,COG3415@2 NA|NA|NA L PFAM Integrase catalytic NIBLCNGB_01375 158787.BSCA_0658 2.9e-26 124.4 Bifidobacteriales lytC 3.2.1.17,3.2.1.96 ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Bacteria 2I2GQ@201174,4D08Z@85004,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 NIBLCNGB_01376 702459.BBPR_0064 5.4e-172 610.1 Bifidobacteriales 1.1.1.339 ko:K19180 ko00523,ko01130,map00523,map01130 R10190 RC00182 ko00000,ko00001,ko01000 Bacteria 2IBI2@201174,4CZUP@85004,COG0451@1,COG0451@2 NA|NA|NA GM NAD dependent epimerase/dehydratase family NIBLCNGB_01377 702459.BBPR_0063 1.7e-190 671.8 Bifidobacteriales Bacteria 2IDHY@201174,4CZ27@85004,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase family NIBLCNGB_01378 702459.BBPR_0062 0.0 1307.4 Bifidobacteriales rgpF ko:K07272 ko00000,ko01000,ko01003,ko01005 Bacteria 2HQS4@201174,4CYYB@85004,COG3754@1,COG3754@2 NA|NA|NA M Rhamnan synthesis protein F NIBLCNGB_01379 702459.BBPR_0061 5.7e-250 869.8 Bifidobacteriales Bacteria 2I8MR@201174,4D0JH@85004,COG2327@1,COG2327@2 NA|NA|NA S Polysaccharide pyruvyl transferase NIBLCNGB_01380 702459.BBPR_0060 4.8e-272 943.3 Bifidobacteriales Bacteria 2AJ90@1,2I28A@201174,319TX@2,4D0A5@85004 NA|NA|NA S Glucosyl transferase GtrII NIBLCNGB_01381 1437610.BREU_1897 3.5e-60 237.7 Bifidobacteriales Bacteria 2GKW1@201174,4D05P@85004,COG2801@1,COG2801@2,COG3415@1,COG3415@2 NA|NA|NA L PFAM Integrase catalytic NIBLCNGB_01382 1437609.BCAL_0101 6.6e-244 849.7 Bifidobacteriales Bacteria 2IBDV@201174,4CZS6@85004,COG4584@1,COG4584@2 NA|NA|NA L PFAM Integrase catalytic NIBLCNGB_01383 326426.Bbr_1401 2.2e-134 485.0 Bifidobacteriales Bacteria 2I90G@201174,4D05J@85004,COG1484@1,COG1484@2 NA|NA|NA L IstB-like ATP binding protein NIBLCNGB_01384 1437610.BREU_1897 6.1e-63 246.5 Bifidobacteriales Bacteria 2GKW1@201174,4D05P@85004,COG2801@1,COG2801@2,COG3415@1,COG3415@2 NA|NA|NA L PFAM Integrase catalytic NIBLCNGB_01385 1437610.BREU_1200 3.8e-147 527.7 Bifidobacteriales gtrB ko:K20534 ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 Bacteria 2I3C0@201174,4D2X0@85004,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 NIBLCNGB_01386 702459.BBPR_0082 1e-229 802.4 Bifidobacteriales rgpD 3.6.3.38,3.6.3.40 ko:K01990,ko:K09689,ko:K09691,ko:K09693 ko02010,map02010 M00249,M00250,M00251,M00254 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.101,3.A.1.103,3.A.1.104 Bacteria 2GIVF@201174,4CZ1B@85004,COG1134@1,COG1134@2 NA|NA|NA GM ABC transporter, ATP-binding protein NIBLCNGB_01387 702459.BBPR_0081 2.7e-149 534.6 Bifidobacteriales rgpC ko:K01992,ko:K09692 ko02010,map02010 M00251,M00254 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.104 Bacteria 2GP5K@201174,4CZ73@85004,COG1682@1,COG1682@2 NA|NA|NA U Transport permease protein NIBLCNGB_01388 702459.BBPR_0080 7.9e-204 716.1 Bifidobacteriales rfbB GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv3464 Bacteria 2GNDU@201174,4CZZY@85004,COG1088@1,COG1088@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily NIBLCNGB_01389 702459.BBPR_0079 1.5e-261 908.3 Bifidobacteriales rmlC 1.1.1.133,5.1.3.13 ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777,R06514 RC00182,RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNY8@201174,4CZ18@85004,COG1091@1,COG1091@2,COG1898@1,COG1898@2 NA|NA|NA M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose NIBLCNGB_01390 702459.BBPR_0078 1.1e-172 612.5 Bifidobacteriales rfbA GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0334 Bacteria 2GP20@201174,4CZ5F@85004,COG1209@1,COG1209@2 NA|NA|NA H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis NIBLCNGB_01391 762211.BSTEL_1802 3.3e-214 751.5 Bifidobacteriales lytC 3.2.1.17,3.2.1.96 ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Bacteria 2I2GQ@201174,4D08Z@85004,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 NIBLCNGB_01392 1437610.BREU_0860 1e-176 626.3 Bifidobacteriales ko:K07133 ko00000 Bacteria 2I96U@201174,4CZD7@85004,COG1373@1,COG1373@2 NA|NA|NA S AAA domain NIBLCNGB_01393 873513.HMPREF6485_2763 2.5e-10 70.9 Bacteroidia ko:K07133 ko00000 Bacteria 2FMQ0@200643,4NGFI@976,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) NIBLCNGB_01394 326426.Bbr_1803 3.5e-186 657.9 Bifidobacteriales Bacteria 2GJM3@201174,4CZ5B@85004,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-related transcriptional attenuator domain NIBLCNGB_01395 216816.GS08_02610 8.1e-165 586.6 Bifidobacteriales Bacteria 2GMZX@201174,4D0DN@85004,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives IS30 family NIBLCNGB_01396 326426.Bbr_0312 3.8e-219 767.3 Bifidobacteriales Bacteria 2GM8F@201174,4D01G@85004,COG3328@1,COG3328@2 NA|NA|NA L Transposase, Mutator family NIBLCNGB_01397 326426.Bbr_1804 4.2e-259 900.2 Bifidobacteriales ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GMGJ@201174,4CZBN@85004,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease NIBLCNGB_01398 326426.Bbr_1805 3.6e-184 651.0 Bifidobacteriales ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GNFW@201174,4CZAW@85004,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter NIBLCNGB_01399 326426.Bbr_1806 4e-144 517.3 Bifidobacteriales ko:K02030,ko:K06950 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2GNQR@201174,4CYT9@85004,COG2206@1,COG2206@2 NA|NA|NA T HD domain NIBLCNGB_01400 326426.Bbr_1807 7.9e-160 569.7 Bifidobacteriales Bacteria 2IBFV@201174,4CYX2@85004,COG0121@1,COG0121@2 NA|NA|NA S Glutamine amidotransferase domain NIBLCNGB_01401 326426.Bbr_1808 0.0 1523.1 Bifidobacteriales kup GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 ko:K03549 ko00000,ko02000 2.A.72 Bacteria 2GMPQ@201174,4CZM3@85004,COG3158@1,COG3158@2 NA|NA|NA P Transport of potassium into the cell NIBLCNGB_01402 326426.Bbr_1809 5.3e-186 656.8 Bifidobacteriales tatD ko:K03424 ko00000,ko01000 Bacteria 2GMJJ@201174,4CYZI@85004,COG0084@1,COG0084@2 NA|NA|NA L TatD related DNase NIBLCNGB_01403 326426.Bbr_1810 0.0 1125.5 Bifidobacteriales yknV ko:K02021,ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 Bacteria 2GITR@201174,4CZ32@85004,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter NIBLCNGB_01404 326426.Bbr_1811 0.0 1218.8 Bifidobacteriales mdlA2 ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,4D028@85004,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter NIBLCNGB_01405 216816.GS08_09990 2.3e-23 114.0 Bifidobacteriales ko:K06921 ko00000 Bacteria 2GMAZ@201174,4CZTD@85004,COG1672@1,COG1672@2 NA|NA|NA S ATPase domain predominantly from Archaea NIBLCNGB_01406 326426.Bbr_1812 1.2e-252 878.6 Bifidobacteriales ko:K07133 ko00000 Bacteria 2GM3Y@201174,4CZTJ@85004,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) NIBLCNGB_01407 216816.GS08_10000 5.7e-193 679.9 Bifidobacteriales Bacteria 2I2H2@201174,4CZDP@85004,COG3507@1,COG3507@2 NA|NA|NA G Glycosyl hydrolases family 43 NIBLCNGB_01408 1437610.BREU_2297 1.4e-153 548.9 Bifidobacteriales ko:K10119 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 2GM2W@201174,4D05E@85004,COG0395@1,COG0395@2 NA|NA|NA U Binding-protein-dependent transport system inner membrane component NIBLCNGB_01409 1437610.BREU_2296 1.3e-176 625.5 Bifidobacteriales ko:K02025,ko:K10118,ko:K15771 ko02010,map02010 M00196,M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.28 Bacteria 2GKJI@201174,4CZCI@85004,COG1175@1,COG1175@2 NA|NA|NA U Binding-protein-dependent transport system inner membrane component NIBLCNGB_01410 216816.GS08_10015 1.8e-242 844.7 Bifidobacteriales ko:K10117 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 2HZAD@201174,4CZ9S@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_01411 216816.GS08_10020 3.1e-195 687.6 Bifidobacteriales Bacteria 2GJ5Q@201174,4D041@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor NIBLCNGB_01412 216816.GS08_10025 0.0 1441.4 Bifidobacteriales lacZ 3.2.1.23 ko:K12308 ko00052,map00052 R01105 RC00452 ko00000,ko00001,ko01000 Bacteria 2GMDT@201174,4CZ6K@85004,COG1874@1,COG1874@2 NA|NA|NA G Beta-galactosidase trimerisation domain NIBLCNGB_01413 216816.GS08_10030 1.6e-268 931.4 Bifidobacteriales ko:K07133 ko00000 Bacteria 2HCYQ@201174,4D2TP@85004,COG1373@1,COG1373@2 NA|NA|NA S AAA domain NIBLCNGB_01414 1437610.BREU_2284 3.4e-54 218.0 Bacteria Bacteria COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator Superfamily NIBLCNGB_01415 1437610.BREU_2284 4e-34 150.2 Bacteria Bacteria COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator Superfamily NIBLCNGB_01416 158787.BSCA_0398 5.7e-21 106.7 Bifidobacteriales 3.2.1.185 ko:K09955,ko:K18205 ko00000,ko01000 GH127 Bacteria 2GM60@201174,4CYSU@85004,COG3533@1,COG3533@2 NA|NA|NA S Beta-L-arabinofuranosidase, GH127 NIBLCNGB_01417 326426.Bbr_1814 0.0 1101.3 Bifidobacteriales oppA ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GJ9N@201174,4CZ3S@85004,COG0747@1,COG0747@2 NA|NA|NA E Bacterial extracellular solute-binding proteins, family 5 Middle NIBLCNGB_01418 216816.GS08_10045 0.0 1384.0 Bifidobacteriales oppD ko:K02031,ko:K02032 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2H3HY@201174,4CYU0@85004,COG1123@1,COG4172@2 NA|NA|NA P Belongs to the ABC transporter superfamily NIBLCNGB_01419 326426.Bbr_1816 1.6e-172 612.1 Bifidobacteriales dppC ko:K02031,ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2GJ9E@201174,4CYQF@85004,COG1173@1,COG1173@2 NA|NA|NA EP N-terminal TM domain of oligopeptide transport permease C NIBLCNGB_01420 216816.GS08_10055 7.9e-177 626.3 Bifidobacteriales appB GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 ko:K02033 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GJ2C@201174,4CYS5@85004,COG0601@1,COG0601@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component NIBLCNGB_01421 216816.GS08_10060 8e-277 959.1 Bifidobacteriales pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 2HCVR@201174,4CZD8@85004,COG3579@1,COG3579@2 NA|NA|NA E Peptidase C1-like family NIBLCNGB_01422 326426.Bbr_1819 1.9e-46 191.4 Bifidobacteriales Bacteria 2AWD6@1,2IP9F@201174,31N94@2,4D137@85004 NA|NA|NA NIBLCNGB_01423 216816.GS08_10075 0.0 1219.9 Bifidobacteriales metG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GK4S@201174,4CZ20@85004,COG0143@1,COG0143@2 NA|NA|NA J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation NIBLCNGB_01424 326426.Bbr_1821 9.4e-121 439.5 Bifidobacteriales Bacteria 2AU2N@1,2IJNI@201174,31JNZ@2,4D047@85004 NA|NA|NA NIBLCNGB_01425 326426.Bbr_1823 2.1e-160 571.6 Bifidobacteriales rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 2GJ9Q@201174,4CZ03@85004,COG0313@1,COG0313@2 NA|NA|NA H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA NIBLCNGB_01427 326426.Bbr_1824 1.5e-256 891.7 Bifidobacteriales ko:K03292,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.2 Bacteria 2HZ98@201174,4CZ0N@85004,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein NIBLCNGB_01428 326426.Bbr_1825 2.5e-180 637.9 Bifidobacteriales apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 2H8YU@201174,4CZW7@85004,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein NIBLCNGB_01429 326426.Bbr_1826 0.0 1165.6 Bifidobacteriales lmrA2 ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,4CZTU@85004,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region NIBLCNGB_01430 326426.Bbr_1827 0.0 1117.4 Bifidobacteriales lmrA1 ko:K02021,ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 Bacteria 2GITR@201174,4CYYV@85004,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter, ATP-binding protein NIBLCNGB_01431 326426.Bbr_1828 1.8e-90 338.6 Bifidobacteriales ydgJ Bacteria 2IMKE@201174,4CYZZ@85004,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein NIBLCNGB_01432 326426.Bbr_1839 2.5e-278 964.1 Bifidobacteriales cycA GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601 Bacteria 2GJ0X@201174,4CZAY@85004,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease NIBLCNGB_01433 326426.Bbr_1840 0.0 1720.3 Bifidobacteriales ko:K02004,ko:K06994 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2I2FK@201174,4CZJR@85004,COG0577@1,COG0577@2,COG1511@1,COG1511@2 NA|NA|NA V FtsX-like permease family NIBLCNGB_01434 326426.Bbr_1841 7.5e-129 466.5 Bifidobacteriales ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJQV@201174,4CYT2@85004,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter NIBLCNGB_01435 326426.Bbr_1842 4.5e-269 933.3 Bifidobacteriales aroP GO:0003333,GO:0003674,GO:0005215,GO:0005302,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008104,GO:0008150,GO:0008320,GO:0008324,GO:0008509,GO:0008514,GO:0008565,GO:0009977,GO:0015031,GO:0015075,GO:0015171,GO:0015173,GO:0015179,GO:0015192,GO:0015196,GO:0015238,GO:0015291,GO:0015318,GO:0015399,GO:0015405,GO:0015450,GO:0015711,GO:0015801,GO:0015807,GO:0015823,GO:0015827,GO:0015828,GO:0015833,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0033036,GO:0034220,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1904680,GO:1905039 ko:K03293,ko:K11732,ko:K11734 ko00000,ko02000 2.A.3.1,2.A.3.1.1,2.A.3.1.3 iAPECO1_1312.APECO1_1472,iECW_1372.ECW_m0628,iEcE24377_1341.EcE24377A_0114,iEcolC_1368.EcolC_3070,iJN746.PP_4495,iUTI89_1310.UTI89_C0576,iWFL_1372.ECW_m0628 Bacteria 2GJ0X@201174,4CZ4X@85004,COG1113@1,COG1113@2 NA|NA|NA E aromatic amino acid transport protein AroP K03293 NIBLCNGB_01436 326426.Bbr_1843 5e-105 387.1 Bifidobacteriales Bacteria 2IBKF@201174,4D0E0@85004,COG5578@1,COG5578@2 NA|NA|NA S Protein of unknown function, DUF624 NIBLCNGB_01437 326426.Bbr_1844 6.8e-153 546.6 Bifidobacteriales rafG ko:K10119 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 2GJNN@201174,4CYZ9@85004,COG0395@1,COG0395@2 NA|NA|NA G ABC transporter permease NIBLCNGB_01438 326426.Bbr_1845 4.4e-147 527.3 Bifidobacteriales malC ko:K02025,ko:K10118,ko:K10241,ko:K15771 ko02010,map02010 M00196,M00206,M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.23,3.A.1.1.28 Bacteria 2I330@201174,4CZJC@85004,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component NIBLCNGB_01439 326426.Bbr_1846 1e-182 646.0 Bifidobacteriales Bacteria 2GJBJ@201174,4CZ1Y@85004,COG1609@1,COG1609@2 NA|NA|NA K Psort location Cytoplasmic, score NIBLCNGB_01440 326426.Bbr_1847 1.6e-252 878.2 Bifidobacteriales amyE ko:K10117 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 2GWCY@201174,4CYWG@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_01441 326426.Bbr_1848 1.2e-102 379.0 Bifidobacteriales Bacteria 2GNRS@201174,4CZD2@85004,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family NIBLCNGB_01442 326426.Bbr_1849 1.2e-59 235.7 Bifidobacteriales Bacteria 2B5DJ@1,2IRRR@201174,31Y80@2,4D1E6@85004 NA|NA|NA S Protein of unknown function (DUF4235) NIBLCNGB_01443 326426.Bbr_1850 4.2e-141 507.3 Bifidobacteriales nfrA 1.5.1.38,1.5.1.39 ko:K19285,ko:K19286 ko00740,ko01100,map00740,map01100 R05705,R05706 RC00126 ko00000,ko00001,ko01000 Bacteria 2I65Z@201174,4CZ5R@85004,COG0778@1,COG0778@2 NA|NA|NA C Nitroreductase family NIBLCNGB_01444 326426.Bbr_1851 0.0 1300.8 Bifidobacteriales pip ko:K01421 ko00000 Bacteria 2GKEM@201174,4CZ9R@85004,COG1511@1,COG1511@2 NA|NA|NA S YhgE Pip domain protein NIBLCNGB_01445 326426.Bbr_1852 3.1e-280 971.1 Bifidobacteriales pip ko:K01421 ko00000 Bacteria 2GKEM@201174,4CZ2A@85004,COG1511@1,COG1511@2 NA|NA|NA S YhgE Pip domain protein NIBLCNGB_01446 762211.BSTEL_2229 1.8e-40 171.4 Bifidobacteriales Bacteria 2B78R@1,2IQGT@201174,320BB@2,4D178@85004 NA|NA|NA NIBLCNGB_01447 1121439.dsat_2904 9.2e-10 70.5 Proteobacteria Bacteria 1NMSQ@1224,2AZ0G@1,31R6J@2 NA|NA|NA NIBLCNGB_01449 1121439.dsat_2904 9.2e-10 70.5 Proteobacteria Bacteria 1NMSQ@1224,2AZ0G@1,31R6J@2 NA|NA|NA NIBLCNGB_01450 326426.Bbr_1853 1.4e-144 518.8 Bifidobacteriales cobB2 ko:K12410 ko00000,ko01000 Bacteria 2GJI3@201174,4CYUW@85004,COG0846@1,COG0846@2 NA|NA|NA K Sir2 family NIBLCNGB_01451 216816.GS08_10305 2.1e-230 804.7 Bifidobacteriales tdcB GO:0003674,GO:0003824,GO:0003941,GO:0004793,GO:0004794,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006565,GO:0006566,GO:0006567,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016597,GO:0016829,GO:0016830,GO:0016832,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJAG@201174,4CYW0@85004,COG1171@1,COG1171@2 NA|NA|NA E Pyridoxal-phosphate dependent enzyme NIBLCNGB_01452 216816.GS08_10310 0.0 1164.8 Bifidobacteriales 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13 Bacteria 2GKS4@201174,4CZT7@85004,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain protein NIBLCNGB_01453 326426.Bbr_1865 2.9e-154 551.2 Bifidobacteriales ko:K10119 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 2GNQW@201174,4D02Q@85004,COG0395@1,COG0395@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component NIBLCNGB_01454 326426.Bbr_1866 1.1e-143 516.2 Bifidobacteriales malC ko:K02025,ko:K10118,ko:K10241,ko:K15771 ko02010,map02010 M00196,M00206,M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.23,3.A.1.1.28 Bacteria 2GKJI@201174,4CZPG@85004,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component NIBLCNGB_01455 326426.Bbr_1867 2.3e-245 854.4 Bifidobacteriales msmE7 ko:K10117 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 2GN9T@201174,4CZ4V@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_01456 326426.Bbr_1868 3.4e-230 803.9 Bifidobacteriales nagC GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 ko:K02565 ko00000,ko03000 Bacteria 2GMBH@201174,4CZK4@85004,COG1846@1,COG1846@2,COG1940@1,COG1940@2 NA|NA|NA GK ROK family NIBLCNGB_01457 326426.Bbr_1869 0.0 1584.3 Bifidobacteriales 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 Bacteria 2GJJ1@201174,4CZJB@85004,COG3345@1,COG3345@2 NA|NA|NA G Glycosyl hydrolase family 36 N-terminal domain NIBLCNGB_01458 326426.Bbr_1870 2e-79 301.6 Bifidobacteriales tadA 3.5.4.1,3.5.4.33,3.8.1.5,6.3.4.19 ko:K01485,ko:K01563,ko:K04075,ko:K11991 ko00240,ko00330,ko00361,ko00625,ko01100,ko01120,map00240,map00330,map00361,map00625,map01100,map01120 R00974,R01411,R02922,R05284,R05367,R05368,R05369,R05370,R07669,R07670,R09597,R10223 RC00074,RC00477,RC00514,RC00809,RC01317,RC01340,RC01341,RC02013,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 2IM3Z@201174,4D0V0@85004,COG0590@1,COG0590@2 NA|NA|NA FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) NIBLCNGB_01459 326426.Bbr_1871 0.0 1288.5 Bifidobacteriales yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 2GIUT@201174,4CZC4@85004,COG0025@1,COG0025@2 NA|NA|NA P Sodium/hydrogen exchanger family NIBLCNGB_01460 326426.Bbr_1872 1.1e-115 422.9 Bifidobacteriales ko:K07090 ko00000 Bacteria 2I5VT@201174,4CZFS@85004,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein NIBLCNGB_01461 326426.Bbr_1873 4.3e-146 523.9 Bifidobacteriales ypfH GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689 ko:K06999 ko00000 Bacteria 2I5NR@201174,4CZJQ@85004,COG0400@1,COG0400@2 NA|NA|NA S Phospholipase/Carboxylesterase NIBLCNGB_01462 326426.Bbr_1874 9.9e-155 552.7 Bifidobacteriales Bacteria 2BFMF@1,2IGC7@201174,329FS@2,4D0RD@85004 NA|NA|NA NIBLCNGB_01463 326426.Bbr_1875 9e-112 409.5 Bifidobacteriales dcd GO:0003674,GO:0003824,GO:0004170,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0015949,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0033973,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 iPC815.YPO1525 Bacteria 2GKQQ@201174,4CZEB@85004,COG0717@1,COG0717@2 NA|NA|NA F Belongs to the dCTP deaminase family NIBLCNGB_01464 326426.Bbr_1876 1e-36 161.4 Bifidobacteriales Bacteria 2DDMI@1,2ICIR@201174,2ZIJN@2,4D00F@85004 NA|NA|NA NIBLCNGB_01465 326426.Bbr_1877 0.0 1837.0 Bifidobacteriales pacL2 3.6.3.8 ko:K01537 ko00000,ko01000 3.A.3.2 Bacteria 2GJJC@201174,4CZ1I@85004,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus NIBLCNGB_01466 1437609.BCAL_1414 2e-16 91.3 Bifidobacteriales ko:K02529 ko00000,ko03000 Bacteria 2GJRG@201174,4CZ05@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor NIBLCNGB_01467 326426.Bbr_1879 7.5e-86 323.2 Bifidobacteriales 2.7.1.208 ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12 Bacteria 2INQB@201174,4D11R@85004,COG2190@1,COG2190@2 NA|NA|NA G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 NIBLCNGB_01468 326426.Bbr_1880 1.6e-288 998.0 Bifidobacteriales nagE 2.7.1.193,2.7.1.199 ko:K02755,ko:K02756,ko:K02757,ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 M00267,M00271,M00809 R02738,R05199 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.13,4.A.1.1.14,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.1.9,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 iSB619.SA_RS08720 Bacteria 2GKPM@201174,4D069@85004,COG1263@1,COG1263@2,COG1264@1,COG1264@2 NA|NA|NA G phosphotransferase system, EIIB NIBLCNGB_01469 326426.Bbr_1881 1.3e-205 722.2 Bifidobacteriales Bacteria 2GJU2@201174,4CZVY@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily NIBLCNGB_01470 326426.Bbr_1882 1.2e-175 622.5 Bifidobacteriales rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 2GJMR@201174,4CZB1@85004,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family NIBLCNGB_01471 326426.Bbr_1883 5.2e-164 583.6 Bifidobacteriales yeaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 4.2.1.9,5.1.3.15 ko:K01687,ko:K01792 ko00010,ko00290,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00010,map00290,map00770,map01100,map01110,map01120,map01130,map01210,map01230 M00019,M00570 R01209,R02739,R04441,R05070 RC00468,RC00563,RC01714 ko00000,ko00001,ko00002,ko01000 Bacteria 2IIUH@201174,4CZWN@85004,COG0676@1,COG0676@2 NA|NA|NA G Aldose 1-epimerase NIBLCNGB_01472 326426.Bbr_1884 3.5e-301 1040.0 Bifidobacteriales galT 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2HNCF@201174,4CZT3@85004,COG4468@1,COG4468@2 NA|NA|NA G UDP-glucose--hexose-1-phosphate uridylyltransferase NIBLCNGB_01473 326426.Bbr_1885 1.6e-271 941.4 Bifidobacteriales Bacteria 2I2F0@201174,4CZ2E@85004,COG0515@1,COG0515@2 NA|NA|NA KLT Domain of unknown function (DUF4032) NIBLCNGB_01474 326426.Bbr_1890 4.3e-211 740.3 Bifidobacteriales ugpC ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko02000 3.A.1.1 Bacteria 2GJCM@201174,4CYU6@85004,COG3842@1,COG3842@2 NA|NA|NA E Belongs to the ABC transporter superfamily NIBLCNGB_01475 326426.Bbr_1891 6e-137 493.4 Bifidobacteriales ko:K03710 ko00000,ko03000 Bacteria 2GJZ1@201174,4D0IV@85004,COG2188@1,COG2188@2 NA|NA|NA K UTRA domain NIBLCNGB_01476 326426.Bbr_1892 2.2e-241 841.3 Bifidobacteriales ulaA 2.7.1.194 ko:K02822,ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 Bacteria 2GMYV@201174,4D064@85004,COG3037@1,COG3037@2 NA|NA|NA S PTS system sugar-specific permease component NIBLCNGB_01477 326426.Bbr_1893 3.7e-45 187.2 Bifidobacteriales ulaB 2.7.1.194 ko:K02822,ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 Bacteria 2IQ7W@201174,4D161@85004,COG3414@1,COG3414@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit NIBLCNGB_01478 326426.Bbr_1894 2.1e-73 281.6 Bifidobacteriales 2.7.1.194,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02821 ko00051,ko00053,ko01100,ko01120,ko02060,map00051,map00053,map01100,map01120,map02060 M00273,M00283,M00550 R03232,R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.7.1 Bacteria 2I8CH@201174,4D0XI@85004,COG1762@1,COG1762@2 NA|NA|NA G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 NIBLCNGB_01479 326426.Bbr_1895 3.1e-220 770.8 Bifidobacteriales 2.4.1.166 ko:K00745 ko00000,ko01000 GT2 Bacteria 2I2GT@201174,4CZ0W@85004,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase like family 2 NIBLCNGB_01480 326426.Bbr_1898 1.3e-190 672.2 Bifidobacteriales nrdF GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0030145,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 iECNA114_1301.ECNA114_2708,iECSF_1327.ECSF_2473,iSFV_1184.SFV_2827,iSF_1195.SF2704,iSFxv_1172.SFxv_2966,iS_1188.S2890 Bacteria 2GK46@201174,4CYQ2@85004,COG0208@1,COG0208@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides NIBLCNGB_01482 326426.Bbr_1899 0.0 1443.3 Bifidobacteriales nrdE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0015949,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 iAPECO1_1312.APECO1_3846,iYO844.BSU17380 Bacteria 2GKX9@201174,4CZF3@85004,COG0209@1,COG0209@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides NIBLCNGB_01483 326426.Bbr_1900 1.6e-88 332.0 Bifidobacteriales nrdI ko:K03647 ko00000 Bacteria 2IM4D@201174,4D0XV@85004,COG1780@1,COG1780@2 NA|NA|NA F Probably involved in ribonucleotide reductase function NIBLCNGB_01484 326426.Bbr_1901 3.1e-43 180.6 Bifidobacteriales nrdH ko:K06191 ko00000 Bacteria 2IRCP@201174,4D17U@85004,COG0695@1,COG0695@2 NA|NA|NA O Glutaredoxin NIBLCNGB_01485 78346.BRUM_1778 4.1e-115 421.0 Bifidobacteriales 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 GH3 Bacteria 2GQQR@201174,4CZ02@85004,COG1472@1,COG1472@2 NA|NA|NA G Fibronectin type III-like domain NIBLCNGB_01486 326426.Bbr_1908 0.0 1340.9 Bifidobacteriales Bacteria 2GIV0@201174,4CYQG@85004,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase NIBLCNGB_01487 326426.Bbr_1909 7.5e-135 486.9 Bifidobacteriales Bacteria 2GN3N@201174,4CZBD@85004,COG1651@1,COG1651@2 NA|NA|NA O Thioredoxin NIBLCNGB_01489 326426.Bbr_1910 2e-216 758.4 Bifidobacteriales Bacteria 2H4RU@201174,4CYY0@85004,COG3583@1,COG3583@2 NA|NA|NA S G5 NIBLCNGB_01490 326426.Bbr_1911 2.9e-168 597.8 Bifidobacteriales ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182,2.1.1.184 ko:K00561,ko:K02528 R10716 RC00003,RC03257 br01600,ko00000,ko01000,ko01504,ko03009 Bacteria 2GKBT@201174,4CYS9@85004,COG0030@1,COG0030@2 NA|NA|NA J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits NIBLCNGB_01491 326426.Bbr_1912 1.7e-176 625.2 Bifidobacteriales ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.1.1.182,2.7.1.148 ko:K00919,ko:K02528,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634,R10716 RC00002,RC00003,RC01439,RC03257 ko00000,ko00001,ko00002,ko01000,ko02000,ko03009 3.A.1.29 iEC55989_1330.EC55989_1304,iLJ478.TM1383,iYO844.BSU00460 Bacteria 2GKXD@201174,4CZMW@85004,COG1947@1,COG1947@2 NA|NA|NA F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol NIBLCNGB_01492 326426.Bbr_1913 4.8e-111 407.1 Bifidobacteriales Bacteria 2E1BJ@1,2IKG0@201174,32WRF@2,4D0S1@85004 NA|NA|NA S LytR cell envelope-related transcriptional attenuator NIBLCNGB_01493 326426.Bbr_1914 2.1e-282 977.6 Bifidobacteriales cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 2GMT1@201174,4CYUH@85004,COG0617@1,COG0617@2 NA|NA|NA J Probable RNA and SrmB- binding site of polymerase A NIBLCNGB_01494 326426.Bbr_1915 2.3e-160 571.6 Bifidobacteriales deoC 3.6.1.13,3.6.1.17,3.6.1.55,3.6.1.61 ko:K01515,ko:K01518,ko:K03574,ko:K18445 ko00230,ko00240,map00230,map00240 R00184,R00969,R01054,R01232,R02805 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 2GWEB@201174,4CZAV@85004,COG0494@1,COG0494@2 NA|NA|NA L Belongs to the Nudix hydrolase family NIBLCNGB_01495 326426.Bbr_1916 0.0 1291.9 Bifidobacteriales Bacteria 2CETP@1,2GMJ0@201174,33P5Y@2,4CZCV@85004 NA|NA|NA NIBLCNGB_01496 326426.Bbr_1917 0.0 2131.3 Bifidobacteriales murJ ko:K03980 ko00000,ko01011,ko02000 2.A.66.4 Bacteria 2GKN0@201174,4CZ8M@85004,COG0728@1,COG0728@2 NA|NA|NA KLT MviN-like protein NIBLCNGB_01497 326426.Bbr_1918 1.1e-176 625.9 Bifidobacteriales trxB GO:0000166,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 ko:K00384,ko:K22345 ko00030,ko00450,map00030,map00450 R01544,R02016,R03596,R09372 RC00013,RC00544,RC02518,RC02873 ko00000,ko00001,ko01000 iPC815.YPO1374 Bacteria 2GKD2@201174,4CYU9@85004,COG0492@1,COG0492@2 NA|NA|NA C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family NIBLCNGB_01498 326426.Bbr_1919 1.2e-214 752.3 Bifidobacteriales parB GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944 ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 2GNRN@201174,4CYUE@85004,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family NIBLCNGB_01499 326426.Bbr_1920 8.1e-174 616.3 Bifidobacteriales parA ko:K03496 ko00000,ko03036,ko04812 Bacteria 2GMU7@201174,4CZ2D@85004,COG1192@1,COG1192@2 NA|NA|NA D CobQ CobB MinD ParA nucleotide binding domain protein NIBLCNGB_01500 326426.Bbr_1921 3.4e-123 447.6 Bifidobacteriales rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 ko00000,ko01000,ko03009,ko03036 Bacteria 2GM9Z@201174,4CZ29@85004,COG0357@1,COG0357@2 NA|NA|NA J Specifically methylates the N7 position of a guanine in 16S rRNA NIBLCNGB_01501 326426.Bbr_1922 5.6e-92 343.6 Bifidobacteriales jag ko:K06346,ko:K09749 ko00000 Bacteria 2GPZK@201174,4CYQQ@85004,COG1847@1,COG1847@2 NA|NA|NA S Putative single-stranded nucleic acids-binding domain NIBLCNGB_01502 326426.Bbr_1923 9.3e-181 639.4 Bifidobacteriales yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 2GJBU@201174,4CYZ2@85004,COG0706@1,COG0706@2 NA|NA|NA U Membrane protein insertase, YidC Oxa1 family NIBLCNGB_01503 326426.Bbr_1925 8.5e-57 226.1 Bifidobacteriales rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536,ko:K08998 ko00000,ko01000,ko03016 Bacteria 2HZPS@201174,4D16S@85004,COG0594@1,COG0594@2 NA|NA|NA J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme NIBLCNGB_01504 326426.Bbr_1926 2.6e-14 83.6 Bifidobacteriales rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02914 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQFY@201174,4D1EF@85004,COG0230@1,COG0230@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL34 family NIBLCNGB_01505 326426.Bbr_0001 3.3e-280 970.3 Bifidobacteriales dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 2GJKI@201174,4CZDW@85004,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids NIBLCNGB_01506 326426.Bbr_0002 5.5e-206 723.4 Bifidobacteriales dnaN GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJK3@201174,4CZTV@85004,COG0592@1,COG0592@2 NA|NA|NA L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria NIBLCNGB_01507 326426.Bbr_0003 1.1e-201 709.1 Bifidobacteriales recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 ko:K03629,ko:K07459 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2GJCS@201174,4CZQT@85004,COG1195@1,COG1195@2 NA|NA|NA L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP NIBLCNGB_01508 326426.Bbr_0004 4.2e-83 313.9 Bifidobacteriales Bacteria 2GNQ4@201174,4D157@85004,COG5512@1,COG5512@2 NA|NA|NA S Protein of unknown function (DUF721) NIBLCNGB_01509 326426.Bbr_0005 0.0 1373.6 Bifidobacteriales gyrB GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02470 ko00000,ko01000,ko03032,ko03400 Bacteria 2GKGP@201174,4CZ47@85004,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner NIBLCNGB_01510 326426.Bbr_0006 0.0 1760.0 Bifidobacteriales gyrA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02469 ko00000,ko01000,ko03032,ko03400 Bacteria 2GJ2Q@201174,4CYRP@85004,COG0188@1,COG0188@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner NIBLCNGB_01511 326426.Bbr_0007 9.3e-50 203.4 Bifidobacteriales GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 Bacteria 2GKZP@201174,4D0XB@85004,COG3266@1,COG3266@2 NA|NA|NA S Transmembrane domain of unknown function (DUF3566) NIBLCNGB_01512 326426.Bbr_0008 2.6e-183 647.9 Bifidobacteriales lacR ko:K02529 ko00000,ko03000 Bacteria 2H5ZG@201174,4CZ8A@85004,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family NIBLCNGB_01513 762211.BSTEL_0991 2.9e-16 91.7 Bifidobacteriales lacS ko:K03292,ko:K11104,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.1,2.A.2.2 Bacteria 2HD4Y@201174,4CZRA@85004,COG2211@1,COG2211@2 NA|NA|NA G Psort location CytoplasmicMembrane, score 10.00 NIBLCNGB_01514 326426.Bbr_0010 0.0 2035.4 Bifidobacteriales lacL 3.2.1.23 ko:K01190,ko:K12111 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 Bacteria 2GMAT@201174,4CYYS@85004,COG3250@1,COG3250@2 NA|NA|NA G Psort location Cytoplasmic, score 8.87 NIBLCNGB_01515 326426.Bbr_0011 4e-203 714.1 Bifidobacteriales Bacteria 2H595@201174,4CZBZ@85004,COG4767@1,COG4767@2 NA|NA|NA V VanZ like family NIBLCNGB_01516 326426.Bbr_0012 2.5e-258 897.5 Bifidobacteriales gdhA 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 R00248 RC00006,RC02799 ko00000,ko00001,ko01000 Bacteria 2GKXG@201174,4CYTN@85004,COG0334@1,COG0334@2 NA|NA|NA E Belongs to the Glu Leu Phe Val dehydrogenases family NIBLCNGB_01517 326426.Bbr_0013 2.5e-194 684.5 Bifidobacteriales Bacteria 28H6R@1,2I9RC@201174,2Z7J3@2,4CZ7J@85004 NA|NA|NA S Psort location CytoplasmicMembrane, score NIBLCNGB_01520 326426.Bbr_0014 1.3e-122 445.7 Bifidobacteriales ko:K07043 ko00000 Bacteria 2GMP6@201174,4CZF9@85004,COG1451@1,COG1451@2 NA|NA|NA S Protein of unknown function DUF45 NIBLCNGB_01522 326426.Bbr_0015 1e-256 892.1 Bifidobacteriales ko:K07133 ko00000 Bacteria 2GM3Y@201174,4D05H@85004,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) NIBLCNGB_01523 326426.Bbr_0016 3.3e-83 314.3 Bifidobacteriales dps GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 ko:K04047 ko00000,ko03036 Bacteria 2IFDP@201174,4CZV3@85004,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family NIBLCNGB_01524 1437610.BREU_2146 7.2e-117 426.8 Bifidobacteriales Bacteria 2GMZX@201174,4D0DN@85004,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives IS30 family NIBLCNGB_01525 1437610.BREU_2242 1.1e-88 332.8 Bifidobacteriales amyE ko:K10117 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 2GWCY@201174,4CYWG@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_01526 326426.Bbr_0018 1e-114 419.5 Bifidobacteriales Bacteria 2IBKF@201174,4D0E0@85004,COG5578@1,COG5578@2 NA|NA|NA S Protein of unknown function, DUF624 NIBLCNGB_01527 326426.Bbr_0019 3.8e-201 707.2 Bifidobacteriales ko:K02529 ko00000,ko03000 Bacteria 2GJY9@201174,4CYU8@85004,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding protein domain NIBLCNGB_01528 326426.Bbr_0020 2.1e-292 1010.7 Bifidobacteriales 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 GH32 Bacteria 2H3S0@201174,4D05M@85004,COG1621@1,COG1621@2 NA|NA|NA G Glycosyl hydrolases family 32 NIBLCNGB_01529 1437610.BREU_2247 7.4e-247 859.4 Bifidobacteriales amyE ko:K10117 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 2GWCY@201174,4CYWG@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_01530 326426.Bbr_0022 0.0 1804.3 Bifidobacteriales 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 GH31 Bacteria 2GP4V@201174,4D005@85004,COG1501@1,COG1501@2 NA|NA|NA G Belongs to the glycosyl hydrolase 31 family NIBLCNGB_01531 326426.Bbr_0023 3e-187 661.0 Bifidobacteriales Bacteria 2GJBJ@201174,4CZ1Y@85004,COG1609@1,COG1609@2 NA|NA|NA K Psort location Cytoplasmic, score NIBLCNGB_01532 326426.Bbr_0024 9.5e-211 739.2 Bifidobacteriales Bacteria 2GMZX@201174,4D0DN@85004,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives IS30 family NIBLCNGB_01533 1437610.BREU_2241 1e-147 529.3 Bifidobacteriales 3.2.1.10,3.2.1.20,3.2.1.93 ko:K01182,ko:K01187,ko:K01226 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R00837,R01718,R01791,R06087,R06088,R06113,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13,GH31 Bacteria 2GKS4@201174,4CZ1E@85004,COG0366@1,COG0366@2 NA|NA|NA G Alpha-amylase domain NIBLCNGB_01534 1437610.BREU_2241 4.1e-52 210.7 Bifidobacteriales 3.2.1.10,3.2.1.20,3.2.1.93 ko:K01182,ko:K01187,ko:K01226 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R00837,R01718,R01791,R06087,R06088,R06113,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13,GH31 Bacteria 2GKS4@201174,4CZ1E@85004,COG0366@1,COG0366@2 NA|NA|NA G Alpha-amylase domain NIBLCNGB_01535 1437610.BREU_2241 7e-75 286.6 Bifidobacteriales 3.2.1.10,3.2.1.20,3.2.1.93 ko:K01182,ko:K01187,ko:K01226 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R00837,R01718,R01791,R06087,R06088,R06113,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13,GH31 Bacteria 2GKS4@201174,4CZ1E@85004,COG0366@1,COG0366@2 NA|NA|NA G Alpha-amylase domain NIBLCNGB_01536 326426.Bbr_0026 5.8e-152 543.5 Bifidobacteriales rafG ko:K10119 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 2GJNN@201174,4CYZ9@85004,COG0395@1,COG0395@2 NA|NA|NA G ABC transporter permease NIBLCNGB_01537 326426.Bbr_0027 4.2e-150 537.3 Bifidobacteriales malC ko:K02025,ko:K10118,ko:K10241,ko:K15771 ko02010,map02010 M00196,M00206,M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.23,3.A.1.1.28 Bacteria 2I330@201174,4CZJC@85004,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component NIBLCNGB_01538 1437610.BREU_2237 1.5e-30 138.3 Bifidobacteriales Bacteria 2GJBJ@201174,4CZ1Y@85004,COG1609@1,COG1609@2 NA|NA|NA K Psort location Cytoplasmic, score NIBLCNGB_01539 1437610.BREU_2237 2e-71 275.0 Bifidobacteriales Bacteria 2GJBJ@201174,4CZ1Y@85004,COG1609@1,COG1609@2 NA|NA|NA K Psort location Cytoplasmic, score NIBLCNGB_01540 1437610.BREU_2236 5.9e-76 290.0 Bifidobacteriales amyE ko:K10117 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 2GWCY@201174,4CYWG@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_01541 1437610.BREU_2236 1.2e-42 179.1 Bifidobacteriales amyE ko:K10117 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 2GWCY@201174,4CYWG@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_01542 1437610.BREU_2236 2e-50 205.3 Bifidobacteriales amyE ko:K10117 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 2GWCY@201174,4CYWG@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_01544 326426.Bbr_0030 5.9e-229 799.7 Bifidobacteriales Bacteria 2GJFD@201174,4CZ06@85004,COG4030@1,COG4030@2 NA|NA|NA M Protein of unknown function (DUF2961) NIBLCNGB_01545 1437610.BREU_2234 3e-254 884.0 Bifidobacteriales amyE ko:K10117 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 2GWCY@201174,4CYWG@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_01546 326426.Bbr_0032 8.9e-187 659.4 Bifidobacteriales Bacteria 2GJBJ@201174,4D00W@85004,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding protein-like domain NIBLCNGB_01547 326426.Bbr_0033 4.4e-266 923.3 Bifidobacteriales amyE ko:K10117 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 2IEBR@201174,4D00M@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_01548 326426.Bbr_0034 2.1e-82 311.6 Bifidobacteriales dps GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 ko:K04047 ko00000,ko03036 Bacteria 2IFDP@201174,4CZV3@85004,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family NIBLCNGB_01549 326426.Bbr_0035 7.6e-231 806.2 Bifidobacteriales ytfL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03699 ko00000,ko02042 Bacteria 2GKN5@201174,4CZKA@85004,COG1253@1,COG1253@2 NA|NA|NA P Transporter associated domain NIBLCNGB_01550 326426.Bbr_0036 1.3e-207 728.8 Bifidobacteriales Bacteria 2GWBV@201174,4CZV8@85004,COG1672@1,COG1672@2 NA|NA|NA S AAA ATPase domain NIBLCNGB_01551 326426.Bbr_0037 2.8e-120 438.0 Bifidobacteriales cah GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008270,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944 4.2.1.1 ko:K01673 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 Bacteria 2GT5H@201174,4D06V@85004,COG0288@1,COG0288@2 NA|NA|NA P Reversible hydration of carbon dioxide NIBLCNGB_01552 326426.Bbr_0038 1.4e-106 392.1 Bifidobacteriales ahpC 1.11.1.15 ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Bacteria 2GM74@201174,4CZXS@85004,COG0450@1,COG0450@2 NA|NA|NA O C-terminal domain of 1-Cys peroxiredoxin NIBLCNGB_01553 326426.Bbr_0039 0.0 1159.8 Bifidobacteriales trxB2 1.8.1.9 ko:K00384 ko00450,map00450 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 Bacteria 2GKD2@201174,4CZ6G@85004,COG0492@1,COG0492@2,COG3634@1,COG3634@2 NA|NA|NA C Thioredoxin domain NIBLCNGB_01554 326426.Bbr_0040 0.0 1403.7 Bifidobacteriales 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 2ICHN@201174,4CYZ7@85004,COG0451@1,COG0451@2 NA|NA|NA GM ADP-glyceromanno-heptose 6-epimerase activity NIBLCNGB_01555 326426.Bbr_0041 5.7e-161 573.5 Bifidobacteriales Bacteria 28H6W@1,2ICGP@201174,2Z7J7@2,4CZUA@85004 NA|NA|NA NIBLCNGB_01556 216816.GS08_07965 0.0 1138.6 Bifidobacteriales Bacteria 2IERA@201174,4D00K@85004,COG4878@1,COG4878@2 NA|NA|NA S Uncharacterised protein conserved in bacteria (DUF2194) NIBLCNGB_01557 326426.Bbr_0044 3.5e-282 976.9 Bifidobacteriales pelF ko:K21011 ko02025,map02025 ko00000,ko00001,ko01003 GT4 Bacteria 2GKEA@201174,4CZ5G@85004,COG0438@1,COG0438@2 NA|NA|NA M Domain of unknown function (DUF3492) NIBLCNGB_01558 547043.BIFPSEUDO_02522 3.5e-272 943.7 Bifidobacteriales pelG ko:K21012 ko02025,map02025 ko00000,ko00001 Bacteria 2IE76@201174,4CZ7D@85004,COG4267@1,COG4267@2 NA|NA|NA S Putative exopolysaccharide Exporter (EPS-E) NIBLCNGB_01559 216816.GS08_07950 1.4e-304 1051.6 Bifidobacteriales cotH ko:K06330 ko00000 Bacteria 2ID5Z@201174,4D02F@85004,COG5337@1,COG5337@2 NA|NA|NA M CotH kinase protein NIBLCNGB_01560 216816.GS08_07945 4.3e-152 543.9 Bifidobacteriales Bacteria 2HZIY@201174,4D0MA@85004,COG5036@1,COG5036@2 NA|NA|NA P VTC domain NIBLCNGB_01561 326426.Bbr_0048 2.7e-109 401.4 Bifidobacteriales Bacteria 2HZFV@201174,4D0AX@85004,COG1285@1,COG1285@2 NA|NA|NA S Domain of unknown function (DUF4956) NIBLCNGB_01562 326426.Bbr_0049 0.0 1488.4 Bifidobacteriales yliE GO:0003674,GO:0003824,GO:0008081,GO:0016787,GO:0016788,GO:0042578,GO:0071111 Bacteria 2I2FR@201174,4D09B@85004,COG2199@1,COG2199@2,COG2200@1,COG2200@2 NA|NA|NA T Putative diguanylate phosphodiesterase NIBLCNGB_01563 326426.Bbr_0050 3.8e-96 357.5 Bifidobacteriales ko:K07133 ko00000 Bacteria 2HCYQ@201174,4D2TP@85004,COG1373@1,COG1373@2 NA|NA|NA S AAA domain NIBLCNGB_01564 326426.Bbr_0051 5.9e-310 1069.3 Bifidobacteriales 3.6.4.12 ko:K03655,ko:K10439,ko:K11708 ko02010,ko02030,ko03440,map02010,map02030,map03440 M00212,M00319 ko00000,ko00001,ko00002,ko01000,ko02000,ko03400 3.A.1.15,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 Bacteria 2I3IG@201174,4CZRW@85004,COG1414@1,COG1414@2,COG2865@1,COG2865@2 NA|NA|NA K Putative ATP-dependent DNA helicase recG C-terminal NIBLCNGB_01565 326426.Bbr_0052 0.0 1744.9 Bifidobacteriales ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 iJN678.ppc Bacteria 2GKDB@201174,4CZS0@85004,COG2352@1,COG2352@2 NA|NA|NA H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle NIBLCNGB_01566 326426.Bbr_0053 0.0 1224.2 Bifidobacteriales yjjP Bacteria 2HZ8C@201174,4CYR2@85004,COG2966@1,COG2966@2,COG3610@1,COG3610@2 NA|NA|NA S Threonine/Serine exporter, ThrE NIBLCNGB_01567 326426.Bbr_0054 4e-44 183.7 Bifidobacteriales putP GO:0003333,GO:0003674,GO:0005215,GO:0005283,GO:0005298,GO:0005342,GO:0005343,GO:0005416,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006820,GO:0006865,GO:0006869,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0010876,GO:0015075,GO:0015077,GO:0015081,GO:0015171,GO:0015291,GO:0015293,GO:0015294,GO:0015318,GO:0015370,GO:0015672,GO:0015711,GO:0015718,GO:0015804,GO:0015824,GO:0015849,GO:0015908,GO:0015912,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0033036,GO:0034220,GO:0035725,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1903825,GO:1905039 ko:K03307,ko:K11928 ko00000,ko02000 2.A.21,2.A.21.2 iSbBS512_1146.SbBS512_E2302 Bacteria 2I041@201174,4CZS2@85004,COG0591@1,COG0591@2 NA|NA|NA E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family NIBLCNGB_01568 326426.Bbr_0055 3.2e-157 561.2 Bifidobacteriales gmk 1.1.1.23,2.7.4.8 ko:K00013,ko:K00942 ko00230,ko00340,ko01100,ko01110,ko01230,map00230,map00340,map01100,map01110,map01230 M00026,M00050 R00332,R01158,R01163,R02090,R03012 RC00002,RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN40@201174,4CZPZ@85004,COG2852@1,COG2852@2 NA|NA|NA S Protein conserved in bacteria NIBLCNGB_01569 326426.Bbr_0056 1.7e-288 998.0 Bifidobacteriales Bacteria 2GJVW@201174,4CZQ4@85004,COG1574@1,COG1574@2 NA|NA|NA S Amidohydrolase family NIBLCNGB_01570 216816.GS08_00230 5.5e-203 713.4 Bifidobacteriales trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GJ9A@201174,4CYXM@85004,COG0180@1,COG0180@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family NIBLCNGB_01571 326426.Bbr_0058 2.1e-40 171.8 Bifidobacteriales Bacteria 2EGRW@1,2HZNH@201174,32FNP@2,4D120@85004 NA|NA|NA S Protein of unknown function (DUF3073) NIBLCNGB_01572 216816.GS08_00240 5.5e-113 413.7 Bifidobacteriales Bacteria 2IF55@201174,4D0XW@85004,COG2197@1,COG2197@2 NA|NA|NA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain NIBLCNGB_01573 216816.GS08_00245 2.7e-208 731.1 Bifidobacteriales 2.7.13.3 ko:K07675,ko:K20263 ko02020,ko02024,map02020,map02024 M00473,M00818 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2IC0A@201174,4D04K@85004,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase NIBLCNGB_01574 216816.GS08_00250 2.5e-224 784.6 Bifidobacteriales Bacteria 2I3AP@201174,4D0YC@85004,COG0477@1,COG0477@2 NA|NA|NA EGP Major Facilitator Superfamily NIBLCNGB_01575 216816.GS08_00255 3.7e-72 277.3 Bifidobacteriales Bacteria 2IQBF@201174,4D10H@85004,COG3255@1,COG3255@2 NA|NA|NA I Sterol carrier protein NIBLCNGB_01576 216816.GS08_00260 0.0 1615.9 Bifidobacteriales glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 R02111 ko00000,ko00001,ko01000 GT35 Bacteria 2GIVZ@201174,4CZ3V@85004,COG0058@1,COG0058@2 NA|NA|NA G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties NIBLCNGB_01577 326426.Bbr_0061 4.5e-35 153.3 Bifidobacteriales Bacteria 2BFAJ@1,2ISGB@201174,3293I@2,4D185@85004 NA|NA|NA NIBLCNGB_01578 326426.Bbr_0062 1.8e-120 438.7 Bifidobacteriales gluP 3.4.21.105 ko:K19225 ko00000,ko01000,ko01002 Bacteria 2GJYG@201174,4CZJ0@85004,COG0705@1,COG0705@2 NA|NA|NA S Rhomboid family NIBLCNGB_01579 326426.Bbr_0063 6.3e-68 263.5 Bifidobacteriales crgA Bacteria 2E4NY@1,2GQPW@201174,32ZHR@2,4D0ZH@85004 NA|NA|NA D Involved in cell division NIBLCNGB_01580 326426.Bbr_0064 1.6e-116 425.6 Bifidobacteriales Bacteria 2GJ9Y@201174,4CZ1A@85004,COG3879@1,COG3879@2 NA|NA|NA S Bacterial protein of unknown function (DUF881) NIBLCNGB_01581 326426.Bbr_0065 1.9e-228 798.1 Bifidobacteriales srtA 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 2GKT6@201174,4CYZ5@85004,COG3764@1,COG3764@2 NA|NA|NA M Sortase family NIBLCNGB_01582 326426.Bbr_0066 2e-120 438.3 Bifidobacteriales trpG GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 ko:K01664,ko:K13950 ko00790,map00790 R01716 RC00010,RC01418 ko00000,ko00001,ko01000 Bacteria 2GJUX@201174,4D09E@85004,COG0512@1,COG0512@2 NA|NA|NA EH para-aminobenzoate synthase glutamine amidotransferase component II NIBLCNGB_01583 326426.Bbr_0067 0.0 1131.7 Bifidobacteriales pknB 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 2GJ1J@201174,4CZFU@85004,COG0515@1,COG0515@2,COG2815@1,COG2815@2 NA|NA|NA KLT Protein tyrosine kinase NIBLCNGB_01584 326426.Bbr_0068 1.3e-171 609.0 Bifidobacteriales Bacteria 2GMPZ@201174,4CYUK@85004,COG0515@1,COG0515@2 NA|NA|NA T Protein tyrosine kinase NIBLCNGB_01585 326426.Bbr_0069 6.5e-260 902.9 Bifidobacteriales pbpA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K05364 ko00550,map00550 R04519 RC00005,RC00049 ko00000,ko00001,ko01011 Bacteria 2GJUQ@201174,4CYTI@85004,COG0768@1,COG0768@2 NA|NA|NA M penicillin-binding protein NIBLCNGB_01586 326426.Bbr_0070 1.2e-278 965.3 Bifidobacteriales rodA GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 ko:K03588,ko:K05364,ko:K05837 ko00550,ko04112,map00550,map04112 R04519 RC00005,RC00049 ko00000,ko00001,ko01011,ko02000,ko03036 2.A.103.1 Bacteria 2GJTI@201174,4CZ67@85004,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family NIBLCNGB_01587 326426.Bbr_0071 6.3e-272 943.0 Bifidobacteriales pstP GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 3.1.3.16 ko:K01090,ko:K20074 ko00000,ko01000,ko01009 Bacteria 2GJ3M@201174,4CZDN@85004,COG0631@1,COG0631@2 NA|NA|NA T Sigma factor PP2C-like phosphatases NIBLCNGB_01588 326426.Bbr_0072 1e-74 286.2 Bifidobacteriales fhaB GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 Bacteria 2GKA7@201174,4D0RN@85004,COG1716@1,COG1716@2 NA|NA|NA T Inner membrane component of T3SS, cytoplasmic domain NIBLCNGB_01589 326426.Bbr_0073 2e-129 468.4 Bifidobacteriales fhaA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 ko:K02283 ko00000,ko02035,ko02044 Bacteria 2GNU2@201174,4CYUI@85004,COG1716@1,COG1716@2 NA|NA|NA T Protein of unknown function (DUF2662) NIBLCNGB_01590 326426.Bbr_0074 0.0 1912.5 Bifidobacteriales dpp4 3.4.14.5 ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Bacteria 2GJ6A@201174,4CZAE@85004,COG1506@1,COG1506@2 NA|NA|NA E Dipeptidyl peptidase IV (DPP IV) N-terminal region NIBLCNGB_01591 326426.Bbr_0075 2e-213 748.0 Bifidobacteriales pldB GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016740,GO:0016746,GO:0016747,GO:0016787,GO:0016788,GO:0044238,GO:0044464,GO:0052689,GO:0071704,GO:0071944 3.1.1.5 ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 iETEC_1333.ETEC_4102,iEcHS_1320.EcHS_A4049 Bacteria 2HZ9U@201174,4CZ5E@85004,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 NIBLCNGB_01592 326426.Bbr_0076 5.1e-87 327.0 Bifidobacteriales hsp20 ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 2HZHR@201174,4D0H9@85004,COG0071@1,COG0071@2 NA|NA|NA O Hsp20/alpha crystallin family NIBLCNGB_01593 326426.Bbr_0077 5e-71 273.9 Bifidobacteriales yddG GO:0003333,GO:0003674,GO:0005215,GO:0005302,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015179,GO:0015192,GO:0015196,GO:0015238,GO:0015318,GO:0015711,GO:0015801,GO:0015807,GO:0015823,GO:0015827,GO:0015828,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 iBWG_1329.BWG_1294,iE2348C_1286.E2348C_1607,iECDH10B_1368.ECDH10B_1604,iECDH1ME8569_1439.ECDH1ME8569_1416,iECS88_1305.ECS88_1565,iEcDH1_1363.EcDH1_2175,iJO1366.b1473,iNRG857_1313.NRG857_07295,iSSON_1240.SSON_1651,iUMN146_1321.UM146_09675 Bacteria 2GM6M@201174,4CZPP@85004,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family NIBLCNGB_01594 326426.Bbr_0077 3.2e-95 354.4 Bifidobacteriales yddG GO:0003333,GO:0003674,GO:0005215,GO:0005302,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015179,GO:0015192,GO:0015196,GO:0015238,GO:0015318,GO:0015711,GO:0015801,GO:0015807,GO:0015823,GO:0015827,GO:0015828,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 iBWG_1329.BWG_1294,iE2348C_1286.E2348C_1607,iECDH10B_1368.ECDH10B_1604,iECDH1ME8569_1439.ECDH1ME8569_1416,iECS88_1305.ECS88_1565,iEcDH1_1363.EcDH1_2175,iJO1366.b1473,iNRG857_1313.NRG857_07295,iSSON_1240.SSON_1651,iUMN146_1321.UM146_09675 Bacteria 2GM6M@201174,4CZPP@85004,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family NIBLCNGB_01595 216816.GS08_00370 2.4e-20 104.0 Bifidobacteriales Bacteria 29P0D@1,2GV4X@201174,309YI@2,4D1M7@85004 NA|NA|NA NIBLCNGB_01596 326426.Bbr_0079 1.5e-253 881.7 Bifidobacteriales Bacteria 2GP6Q@201174,4CYXF@85004,COG0627@1,COG0627@2 NA|NA|NA S Putative esterase NIBLCNGB_01597 326426.Bbr_0080 0.0 1693.3 Bifidobacteriales lysX Bacteria 2GM2C@201174,4CYW5@85004,COG2898@1,COG2898@2 NA|NA|NA S Uncharacterised conserved protein (DUF2156) NIBLCNGB_01598 326426.Bbr_0081 5.3e-200 703.4 Bifidobacteriales msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K07305,ko:K12267 ko00000,ko01000 Bacteria 2GJ1S@201174,4CZXJ@85004,COG0225@1,COG0225@2,COG0229@1,COG0229@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine NIBLCNGB_01599 326426.Bbr_0082 6.3e-131 473.4 Bifidobacteriales ko:K07005 ko00000 Bacteria 2IGUA@201174,4D0SF@85004,COG3467@1,COG3467@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase NIBLCNGB_01600 326426.Bbr_0083 3.6e-199 700.7 Bifidobacteriales Bacteria 2IAAQ@201174,4CZAM@85004,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family NIBLCNGB_01601 326426.Bbr_0084 1e-70 273.1 Bifidobacteriales Bacteria 2I2IF@201174,4CYW6@85004,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 NIBLCNGB_01602 326426.Bbr_0085 0.0 2148.2 Bifidobacteriales Bacteria 2GJ4Y@201174,4CZNN@85004,COG1061@1,COG1061@2,COG3886@1,COG3886@2 NA|NA|NA KL Domain of unknown function (DUF3427) NIBLCNGB_01603 216816.GS08_00405 3.1e-74 284.3 Bifidobacteriales nudG GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55,3.6.1.65 ko:K03574,ko:K08320 ko00000,ko01000,ko03400 iE2348C_1286.E2348C_1887,iECP_1309.ECP_1705,iLF82_1304.LF82_1533,iNRG857_1313.NRG857_08815,iPC815.YPO2167,iSSON_1240.SSON_1397 Bacteria 2I2GY@201174,4D0UJ@85004,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain NIBLCNGB_01604 326426.Bbr_0086 1.2e-52 212.2 Bifidobacteriales ybjQ Bacteria 2IQNY@201174,4D0ZM@85004,COG0393@1,COG0393@2 NA|NA|NA S Putative heavy-metal-binding NIBLCNGB_01605 326426.Bbr_0087 3.8e-143 514.2 Bifidobacteriales yplQ ko:K11068 ko00000,ko02042 Bacteria 2HRAC@201174,4D0D6@85004,COG1272@1,COG1272@2 NA|NA|NA S Haemolysin-III related NIBLCNGB_01607 326426.Bbr_0088 1e-259 902.1 Bifidobacteriales tgt 2.4.2.29 ko:K00773 R03789,R10209 RC00063 ko00000,ko01000,ko03016 Bacteria 2GMWY@201174,4CZNX@85004,COG0343@1,COG0343@2 NA|NA|NA F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) NIBLCNGB_01608 326426.Bbr_0089 8.4e-263 912.9 Bifidobacteriales degP ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJ96@201174,4CZAP@85004,COG0265@1,COG0265@2 NA|NA|NA O Domain present in PSD-95, Dlg, and ZO-1/2. NIBLCNGB_01610 326426.Bbr_0090 0.0 1510.0 Bifidobacteriales cadA Bacteria 2GIRF@201174,4CZ4F@85004,COG2217@1,COG2217@2 NA|NA|NA P E1-E2 ATPase NIBLCNGB_01611 326426.Bbr_0091 1e-276 958.7 Bifidobacteriales fprA 1.18.1.2,1.19.1.1 ko:K00528 R10159 ko00000,ko01000 Bacteria 2GJ4A@201174,4CZIT@85004,COG0493@1,COG0493@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase NIBLCNGB_01612 216816.GS08_00460 2e-169 601.7 Bifidobacteriales htpX GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03799 M00743 ko00000,ko00002,ko01000,ko01002 Bacteria 2GMJF@201174,4CYVY@85004,COG0501@1,COG0501@2 NA|NA|NA O Belongs to the peptidase M48B family NIBLCNGB_01614 326426.Bbr_0093 1.8e-170 605.1 Bifidobacteriales yicL Bacteria 2HZCH@201174,4CZRZ@85004,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family NIBLCNGB_01615 326426.Bbr_0094 1.7e-196 691.8 Bifidobacteriales fbaA GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 iZ_1308.Z4263 Bacteria 2GM5P@201174,4CZJI@85004,COG0191@1,COG0191@2 NA|NA|NA G Fructose-bisphosphate aldolase class-II NIBLCNGB_01616 326426.Bbr_0095 6.8e-245 852.8 Bifidobacteriales purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMP4@201174,4CZ0U@85004,COG0104@1,COG0104@2 NA|NA|NA F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP NIBLCNGB_01617 216816.GS08_00505 5.3e-281 973.0 Bifidobacteriales clcA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006821,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015672,GO:0015698,GO:0015706,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0031404,GO:0034220,GO:0042802,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 ko:K03281,ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4,2.A.49 iAF1260.b0155,iB21_1397.B21_00153,iBWG_1329.BWG_0148,iE2348C_1286.E2348C_0162,iEC042_1314.EC042_0155,iEC55989_1330.EC55989_0149,iECBD_1354.ECBD_3463,iECDH10B_1368.ECDH10B_0135,iECDH1ME8569_1439.ECDH1ME8569_0149,iECD_1391.ECD_00154,iECIAI1_1343.ECIAI1_0153,iECO103_1326.ECO103_0155,iECSE_1348.ECSE_0156,iECUMN_1333.ECUMN_0152,iECW_1372.ECW_m0152,iEKO11_1354.EKO11_3761,iETEC_1333.ETEC_0151,iEcDH1_1363.EcDH1_3447,iEcE24377_1341.EcE24377A_0160,iEcolC_1368.EcolC_3504,iJO1366.b0155,iSSON_1240.SSON_0167,iUMNK88_1353.UMNK88_159,iWFL_1372.ECW_m0152,iY75_1357.Y75_RS00790,iZ_1308.Z0166 Bacteria 2GPPN@201174,4CZQR@85004,COG0038@1,COG0038@2,COG0569@1,COG0569@2 NA|NA|NA P Voltage gated chloride channel NIBLCNGB_01618 326426.Bbr_0097 1.1e-123 449.9 Bifidobacteriales ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 2IC26@201174,4D0RK@85004,COG0239@1,COG0239@2 NA|NA|NA U Important for reducing fluoride concentration in the cell, thus reducing its toxicity NIBLCNGB_01619 216816.GS08_00515 8.7e-58 229.6 Bifidobacteriales crcB ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 2IC26@201174,4D14T@85004,COG0239@1,COG0239@2 NA|NA|NA U Important for reducing fluoride concentration in the cell, thus reducing its toxicity NIBLCNGB_01620 326426.Bbr_0099 2.4e-203 714.5 Bifidobacteriales ko:K02529,ko:K03484 ko00000,ko03000 Bacteria 2GMHV@201174,4CZ3G@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor NIBLCNGB_01622 326426.Bbr_0100 6.1e-301 1039.3 Bifidobacteriales gtfA GO:0003674,GO:0003824,GO:0004645,GO:0005975,GO:0005976,GO:0006066,GO:0006073,GO:0008150,GO:0008152,GO:0009018,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0019400,GO:0019751,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0051472,GO:0071704,GO:1901615 2.4.1.329,2.4.1.7 ko:K00690,ko:K21350 ko00500,map00500 R00803 RC00028 ko00000,ko00001,ko01000 GH13 Bacteria 2GNEC@201174,4CZ4T@85004,COG0366@1,COG0366@2 NA|NA|NA G Domain of unknown function (DUF1964) NIBLCNGB_01623 326426.Bbr_0101 2.3e-277 961.1 Bifidobacteriales scrT Bacteria 2GJZG@201174,4CZ93@85004,COG2211@1,COG2211@2 NA|NA|NA G Transporter major facilitator family protein NIBLCNGB_01624 326426.Bbr_0102 2.8e-180 637.9 Bifidobacteriales ko:K02529,ko:K03484 ko00000,ko03000 Bacteria 2GMHV@201174,4CZ3G@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor NIBLCNGB_01625 326426.Bbr_0103 2.6e-250 870.9 Bifidobacteriales yhjE ko:K03762 ko00000,ko02000 2.A.1.6.4 Bacteria 2GIYR@201174,4CYY8@85004,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter NIBLCNGB_01626 326426.Bbr_0104 2.4e-203 714.5 Bifidobacteriales ilvC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKXA@201174,4CZBR@85004,COG0059@1,COG0059@2 NA|NA|NA H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate NIBLCNGB_01627 326426.Bbr_0110 3.7e-204 717.2 Bifidobacteriales ilvC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKXA@201174,4CZBR@85004,COG0059@1,COG0059@2 NA|NA|NA H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate NIBLCNGB_01628 1437610.BREU_0338 4.3e-149 533.9 Bifidobacteriales Bacteria 28JTN@1,2IH1U@201174,2Z9IV@2,4D20Y@85004 NA|NA|NA S Psort location Cytoplasmic, score NIBLCNGB_01629 216816.GS08_00580 1.2e-191 675.6 Bifidobacteriales Bacteria 2IR8X@201174,4D23Q@85004,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator NIBLCNGB_01630 216816.GS08_00585 0.0 1250.3 Bifidobacteriales 3.2.1.10,3.2.1.20,3.2.1.93 ko:K01182,ko:K01187,ko:K01226 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R00837,R01718,R01791,R06087,R06088,R06113,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13,GH31 Bacteria 2GKS4@201174,4CZ1E@85004,COG0366@1,COG0366@2 NA|NA|NA G Alpha-amylase domain NIBLCNGB_01631 326426.Bbr_0112 3e-187 661.0 Bifidobacteriales Bacteria 2GJBJ@201174,4CZ1Y@85004,COG1609@1,COG1609@2 NA|NA|NA K Psort location Cytoplasmic, score NIBLCNGB_01632 326426.Bbr_0113 0.0 2769.6 Bifidobacteriales Bacteria 2HH2U@201174,4CZ5N@85004,COG4932@1,COG4932@2 NA|NA|NA M cell wall anchor domain protein NIBLCNGB_01633 326426.Bbr_0114 0.0 1111.3 Bifidobacteriales Bacteria 2IMAM@201174,4D140@85004,COG4932@1,COG4932@2 NA|NA|NA M domain protein NIBLCNGB_01634 326426.Bbr_0115 2.2e-171 608.2 Bifidobacteriales 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 2GNWT@201174,4CZMM@85004,COG3764@1,COG3764@2 NA|NA|NA M Sortase family NIBLCNGB_01635 326426.Bbr_0116 0.0 1480.7 Bifidobacteriales malQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.4.1.18,2.4.1.25,3.2.1.196,5.4.99.15 ko:K00700,ko:K00705,ko:K02438,ko:K06044 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R01824,R02110,R02111,R05196,R09995 RC00049 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13,GH77 iJN678.malQ Bacteria 2GM5Z@201174,4CZ0F@85004,COG1640@1,COG1640@2 NA|NA|NA G 4-alpha-glucanotransferase NIBLCNGB_01636 326426.Bbr_0117 0.0 1183.7 Bifidobacteriales malL 3.2.1.1,5.4.99.16 ko:K05343 ko00500,ko01100,map00500,map01100 R01557,R02108,R02112,R11262 RC01816 ko00000,ko00001,ko01000 GH13 Bacteria 2GIV1@201174,4CZ7N@85004,COG0366@1,COG0366@2 NA|NA|NA G Alpha-amylase domain NIBLCNGB_01637 326426.Bbr_0118 2.2e-232 811.2 Bifidobacteriales malE ko:K15770 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 Bacteria 2GJ8S@201174,4CZ8G@85004,COG2182@1,COG2182@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_01638 326426.Bbr_0119 4.1e-251 873.6 Bifidobacteriales malF ko:K02025,ko:K02026,ko:K10118,ko:K10241,ko:K15771 ko02010,map02010 M00196,M00206,M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.23,3.A.1.1.28 Bacteria 2GJGB@201174,4CYZ8@85004,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component NIBLCNGB_01639 326426.Bbr_0120 2.3e-162 578.2 Bifidobacteriales malG ko:K15772 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 Bacteria 2I2EZ@201174,4CZDE@85004,COG3833@1,COG3833@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component NIBLCNGB_01640 1437610.BREU_0347 0.0 1294.3 Bifidobacteriales pulA 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 R02111 ko00000,ko00001,ko01000 CBM48,GH13 Bacteria 2I2GM@201174,4CYSS@85004,COG1523@1,COG1523@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family NIBLCNGB_01641 1437610.BREU_0348 5.7e-175 620.2 Bifidobacteriales ko:K07025 ko00000 Bacteria 2I2GN@201174,4CZF4@85004,COG1011@1,COG1011@2 NA|NA|NA S HAD-hyrolase-like NIBLCNGB_01642 1437610.BREU_0349 1.1e-144 519.2 Bifidobacteriales traX Bacteria 2AYHW@1,2I9DQ@201174,32WBP@2,4CYRI@85004 NA|NA|NA S TraX protein NIBLCNGB_01643 326426.Bbr_0122 4.4e-194 683.7 Bifidobacteriales Bacteria 2GJBJ@201174,4CZ1Y@85004,COG1609@1,COG1609@2 NA|NA|NA K Psort location Cytoplasmic, score NIBLCNGB_01644 566552.BIFCAT_01374 5.9e-103 380.2 Bifidobacteriales ko:K07450 ko00000 Bacteria 2IDNQ@201174,4CZVV@85004,COG2452@1,COG2452@2 NA|NA|NA L Resolvase, N terminal domain NIBLCNGB_01645 216816.GS08_01860 8.6e-187 659.8 Bifidobacteriales ko:K07496 ko00000 Bacteria 2GM6K@201174,4CZ11@85004,COG0675@1,COG0675@2 NA|NA|NA L Helix-turn-helix domain NIBLCNGB_01646 326426.Bbr_0124 0.0 1134.0 Bifidobacteriales dnaK GO:0000302,GO:0000303,GO:0000305,GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016310,GO:0019222,GO:0019538,GO:0019899,GO:0030112,GO:0030162,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031975,GO:0031982,GO:0032268,GO:0032270,GO:0033554,GO:0034599,GO:0034614,GO:0035375,GO:0036211,GO:0040007,GO:0042221,GO:0042603,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043388,GO:0043412,GO:0044044,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046677,GO:0046688,GO:0046777,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051099,GO:0051101,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070613,GO:0070887,GO:0071450,GO:0071451,GO:0071704,GO:0071944,GO:0080090,GO:0097691,GO:1901564,GO:1901700,GO:1901701,GO:1903317,GO:1903319,GO:1903561,GO:2000677,GO:2000679 ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 2GJTY@201174,4CZDX@85004,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein NIBLCNGB_01647 326426.Bbr_0125 5.2e-58 231.1 Bifidobacteriales grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 ko:K02652,ko:K03687 ko00000,ko02035,ko02044,ko03029,ko03110 3.A.15.2 Bacteria 2GP4F@201174,4CZJ6@85004,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ NIBLCNGB_01648 326426.Bbr_0126 9.4e-157 559.7 Bifidobacteriales dnaJ1 ko:K03686,ko:K05516 ko00000,ko03029,ko03036,ko03110 Bacteria 2GJKK@201174,4CZ68@85004,COG0484@1,COG0484@2 NA|NA|NA O DnaJ molecular chaperone homology domain NIBLCNGB_01649 326426.Bbr_0127 1.2e-103 382.5 Bifidobacteriales hspR ko:K13640 ko00000,ko03000 Bacteria 2IQJ4@201174,4D0Q7@85004,COG0789@1,COG0789@2 NA|NA|NA K transcriptional regulator, MerR family NIBLCNGB_01650 1437610.BREU_1929 3.1e-17 93.6 Bifidobacteriales ko:K03458 ko00000 2.A.40 Bacteria 2GV9H@201174,4CZYX@85004,COG2233@1,COG2233@2 NA|NA|NA F Psort location CytoplasmicMembrane, score 10.00 NIBLCNGB_01651 1437610.BREU_1927 1.5e-114 419.1 Bifidobacteriales luxC 1.2.1.50 ko:K03400 ko02020,ko02024,map02020,map02024 R10549 RC00004,RC00184 ko00000,ko00001,ko01000 Bacteria 2HZAQ@201174,4CZDA@85004,COG1012@1,COG1012@2 NA|NA|NA C Acyl-CoA reductase (LuxC) NIBLCNGB_01652 326426.Bbr_0129 1.1e-139 502.7 Bifidobacteriales Bacteria 2GIX2@201174,4D0FH@85004,COG1028@1,COG1028@2 NA|NA|NA IQ Oxidoreductase, short chain dehydrogenase reductase family protein NIBLCNGB_01653 326426.Bbr_0130 1.5e-126 458.8 Bifidobacteriales Bacteria 2GJNG@201174,4CYZV@85004,COG0637@1,COG0637@2 NA|NA|NA S HAD hydrolase, family IA, variant 3 NIBLCNGB_01654 326426.Bbr_0131 2.1e-134 485.0 Bifidobacteriales dedA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03975 ko00000 Bacteria 2GKGR@201174,4CZ7Y@85004,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein NIBLCNGB_01655 326426.Bbr_0132 5.8e-125 453.8 Bifidobacteriales cpaE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K04562 ko00000,ko02035 Bacteria 2HZIH@201174,4D0JG@85004,COG0455@1,COG0455@2 NA|NA|NA D bacterial-type flagellum organization NIBLCNGB_01656 326426.Bbr_0133 3.8e-190 670.6 Bifidobacteriales cpaF ko:K02283 ko00000,ko02035,ko02044 Bacteria 2GKKJ@201174,4CZF2@85004,COG4962@1,COG4962@2 NA|NA|NA U Type II IV secretion system protein NIBLCNGB_01657 326426.Bbr_0134 3.4e-74 284.3 Bifidobacteriales ko:K12510 ko00000,ko02044 Bacteria 2GRXU@201174,4D1A3@85004,COG4965@1,COG4965@2 NA|NA|NA U Type ii secretion system NIBLCNGB_01658 326426.Bbr_0135 5.8e-115 420.2 Bifidobacteriales gspF ko:K12510,ko:K12511 ko00000,ko02044 Bacteria 2I2FP@201174,4D16W@85004,COG2064@1,COG2064@2 NA|NA|NA NU Type II secretion system (T2SS), protein F NIBLCNGB_01659 326426.Bbr_0136 1.1e-41 175.6 Bifidobacteriales Bacteria 2EHCF@1,2GR72@201174,33B4A@2,4D1FR@85004 NA|NA|NA S Protein of unknown function (DUF4244) NIBLCNGB_01660 326426.Bbr_0137 1.4e-57 228.8 Bifidobacteriales ko:K12513 ko00000,ko02044 Bacteria 2GT3N@201174,4D1E4@85004,COG4961@1,COG4961@2 NA|NA|NA U TadE-like protein NIBLCNGB_01661 326426.Bbr_0138 2.5e-53 214.5 Bifidobacteriales Bacteria 2DRBM@1,2HZRZ@201174,33B4F@2,4D1G6@85004 NA|NA|NA S TIGRFAM helicase secretion neighborhood TadE-like protein NIBLCNGB_01662 326426.Bbr_0139 1.1e-214 752.3 Bifidobacteriales dagK GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 R02240 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2GK3P@201174,4CZ1S@85004,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain protein NIBLCNGB_01663 326426.Bbr_0140 3.5e-95 354.4 Bifidobacteriales Bacteria 2GND5@201174,4CZUU@85004,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family NIBLCNGB_01664 326426.Bbr_0141 0.0 1221.1 Bifidobacteriales dnaX GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJKA@201174,4CZMY@85004,COG2812@1,COG2812@2 NA|NA|NA L DNA polymerase III subunit gamma tau NIBLCNGB_01665 326426.Bbr_0142 8.7e-110 402.9 Bifidobacteriales recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2GJY0@201174,4CZRI@85004,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO NIBLCNGB_01666 326426.Bbr_0144 5e-197 693.7 Bifidobacteriales 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 2GNWT@201174,4CZMM@85004,COG3764@1,COG3764@2 NA|NA|NA M Sortase family NIBLCNGB_01667 326426.Bbr_0145 2.8e-40 171.0 Bacteria Bacteria COG4823@1,COG4823@2 NA|NA|NA V Abi-like protein NIBLCNGB_01668 326426.Bbr_0146 5.1e-179 633.6 Bifidobacteriales 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GZ30@201174,4CYSX@85004,COG2865@1,COG2865@2 NA|NA|NA K Putative ATP-dependent DNA helicase recG C-terminal NIBLCNGB_01669 326426.Bbr_0147 1.1e-133 482.6 Bifidobacteriales ask GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 ko:K00928,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN0G@201174,4CYSD@85004,COG0527@1,COG0527@2 NA|NA|NA E Amino acid kinase family NIBLCNGB_01670 326426.Bbr_0148 5.1e-96 357.1 Bifidobacteriales askB 1.1.1.3,2.7.2.4 ko:K00928,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN0G@201174,4D00P@85004,COG0527@1,COG0527@2 NA|NA|NA E ACT domain NIBLCNGB_01671 326426.Bbr_0149 2.9e-212 744.2 Bifidobacteriales asd GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0030312,GO:0036094,GO:0040007,GO:0043891,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071944,GO:0097159,GO:1901265,GO:1901363 1.2.1.11,1.2.1.12 ko:K00133,ko:K00134 ko00010,ko00260,ko00261,ko00270,ko00300,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04066,ko05010,map00010,map00260,map00261,map00270,map00300,map00710,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04066,map05010 M00001,M00002,M00003,M00016,M00017,M00018,M00033,M00165,M00166,M00308,M00525,M00526,M00527,M00552 R01061,R02291 RC00149,RC00684 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2GJJ8@201174,4CZPY@85004,COG0136@1,COG0136@2 NA|NA|NA E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate NIBLCNGB_01672 216816.GS08_00795 9.6e-112 409.5 Bifidobacteriales Bacteria 2C7PT@1,2GM64@201174,2ZXN2@2,4CYPY@85004 NA|NA|NA NIBLCNGB_01673 326426.Bbr_0160 9.9e-174 615.9 Bifidobacteriales Bacteria 2I8IU@201174,4D0HP@85004,COG0648@1,COG0648@2 NA|NA|NA L Domain of unknown function (DUF4862) NIBLCNGB_01674 326426.Bbr_0161 3e-171 607.8 Bifidobacteriales 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJCQ@201174,4D0EX@85004,COG1940@1,COG1940@2 NA|NA|NA GK ROK family NIBLCNGB_01675 326426.Bbr_0162 1.3e-125 455.7 Bifidobacteriales nanE 5.1.3.9 ko:K01788 ko00520,map00520 R02087 RC00290 ko00000,ko00001,ko01000 Bacteria 2GTWV@201174,4CZK9@85004,COG3010@1,COG3010@2 NA|NA|NA G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) NIBLCNGB_01676 326426.Bbr_0163 3.3e-160 570.9 Bacteria 3.5.1.106 ko:K15357 ko00760,ko01120,map00760,map01120 M00622 R09126 RC00323,RC02431 ko00000,ko00001,ko00002,ko01000 Bacteria COG2267@1,COG2267@2 NA|NA|NA I carboxylic ester hydrolase activity NIBLCNGB_01677 326426.Bbr_0164 1.6e-301 1041.2 Bifidobacteriales ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GK4Y@201174,4CYSK@85004,COG0747@1,COG0747@2 NA|NA|NA E Bacterial extracellular solute-binding proteins, family 5 Middle NIBLCNGB_01678 326426.Bbr_0165 6.6e-152 543.5 Bifidobacteriales oppB6 ko:K02033 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GK0Z@201174,4D2RG@85004,COG0601@1,COG0601@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component NIBLCNGB_01679 326426.Bbr_0166 0.0 1284.6 Bifidobacteriales oppD ko:K02031,ko:K02032,ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2GIXV@201174,4D0C4@85004,COG0444@1,COG0444@2,COG1173@1,COG1173@2 NA|NA|NA EP Oligopeptide/dipeptide transporter, C-terminal region NIBLCNGB_01680 326426.Bbr_0167 6.5e-148 530.0 Bifidobacteriales oppF ko:K02032 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2H4BW@201174,4CYR3@85004,COG4608@1,COG4608@2 NA|NA|NA E ATPases associated with a variety of cellular activities NIBLCNGB_01681 326426.Bbr_0168 1.7e-179 635.2 Bifidobacteriales nanL 4.1.2.28,4.3.3.7 ko:K01714,ko:K22397 ko00040,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00040,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R01782,R10147 RC00307,RC00572,RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJDB@201174,4D04B@85004,COG0329@1,COG0329@2 NA|NA|NA EM Dihydrodipicolinate synthetase family NIBLCNGB_01682 326426.Bbr_0169 1.4e-147 528.9 Bifidobacteriales nagB 3.1.1.31,3.5.99.6 ko:K01057,ko:K02564 ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R00765,R02035 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK7F@201174,4CYYE@85004,COG0363@1,COG0363@2 NA|NA|NA G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion NIBLCNGB_01683 762211.BSTEL_0833 1.6e-13 81.6 Bifidobacteriales nagA 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 R02059 RC00166,RC00300 ko00000,ko00001,ko01000 Bacteria 2GK1E@201174,4CZKB@85004,COG1820@1,COG1820@2 NA|NA|NA G Amidohydrolase family NIBLCNGB_01684 326426.Bbr_0171 0.0 1543.9 Bifidobacteriales nanI 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 GH33 Bacteria 2I0CJ@201174,4D02H@85004,COG4409@1,COG4409@2 NA|NA|NA G BNR repeat-like domain NIBLCNGB_01685 326426.Bbr_0172 1.5e-244 851.7 Bifidobacteriales ko:K07133 ko00000 Bacteria 2GK1Q@201174,4D0A9@85004,COG1373@1,COG1373@2 NA|NA|NA P Domain of unknown function (DUF4143) NIBLCNGB_01686 326426.Bbr_0173 9e-153 546.2 Bifidobacteriales ko:K05799 ko00000,ko03000 Bacteria 2GJ82@201174,4D0K7@85004,COG2186@1,COG2186@2 NA|NA|NA K FCD NIBLCNGB_01687 326426.Bbr_0174 6.8e-273 946.0 Bifidobacteriales Bacteria 2GNKK@201174,4CZMC@85004,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase NIBLCNGB_01688 326426.Bbr_0175 0.0 1265.0 Bifidobacteriales leuA GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GISX@201174,4CZYW@85004,COG0119@1,COG0119@2 NA|NA|NA E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) NIBLCNGB_01689 326426.Bbr_0176 0.0 1369.4 Bifidobacteriales mrcB 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 2GK21@201174,4CZQZ@85004,COG0744@1,COG0744@2 NA|NA|NA M Transglycosylase NIBLCNGB_01690 326426.Bbr_0177 3.6e-165 587.8 Bifidobacteriales 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 2HIXE@201174,4CYS6@85004,COG0671@1,COG0671@2 NA|NA|NA I PAP2 superfamily NIBLCNGB_01691 326426.Bbr_0178 0.0 1831.6 Bifidobacteriales topA GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria 2GJU7@201174,4CZ85@85004,COG0550@1,COG0550@2,COG1754@1,COG1754@2 NA|NA|NA L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone NIBLCNGB_01692 326426.Bbr_0179 2.4e-116 424.9 Bifidobacteriales tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNTI@201174,4CYQ8@85004,COG0125@1,COG0125@2 NA|NA|NA F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis NIBLCNGB_01693 326426.Bbr_0180 1.9e-206 724.9 Bifidobacteriales holB GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJ8C@201174,4CZ4Y@85004,COG0470@1,COG0470@2 NA|NA|NA L DNA polymerase III NIBLCNGB_01694 326426.Bbr_0181 2.3e-105 388.3 Bifidobacteriales ko:K02529 ko00000,ko03000 Bacteria 2GJRG@201174,4CZ05@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor NIBLCNGB_01695 326426.Bbr_0182 3.3e-37 160.6 Bifidobacteriales ptsH ko:K11189 ko00000,ko02000 4.A.2.1 Bacteria 2GQX6@201174,4D19B@85004,COG1925@1,COG1925@2 NA|NA|NA G PTS HPr component phosphorylation site NIBLCNGB_01696 326426.Bbr_0183 3.9e-293 1013.4 Bifidobacteriales ptsI 2.7.3.9 ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 8.A.7 Bacteria 2GIZZ@201174,4CZ52@85004,COG1080@1,COG1080@2 NA|NA|NA G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) NIBLCNGB_01697 216816.GS08_00835 1.4e-104 385.6 Bifidobacteriales ko:K06910 ko00000 Bacteria 2I5K1@201174,4CZSW@85004,COG1881@1,COG1881@2 NA|NA|NA S Phosphatidylethanolamine-binding protein NIBLCNGB_01698 326426.Bbr_0187 2.7e-310 1070.5 Bifidobacteriales pepD ko:K08659 ko00000,ko01000,ko01002 Bacteria 2GM80@201174,4CZI5@85004,COG4690@1,COG4690@2 NA|NA|NA E Peptidase family C69 NIBLCNGB_01699 326426.Bbr_0188 1.2e-288 998.4 Bifidobacteriales fhs GO:0000096,GO:0000097,GO:0000105,GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006547,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0052803,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.5,3.5.4.9,6.3.4.3 ko:K00288,ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00141,M00377 R00943,R01220,R01655 RC00026,RC00111,RC00202,RC00578 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GT0X@201174,4CZ7P@85004,COG2759@1,COG2759@2 NA|NA|NA F Formate-tetrahydrofolate ligase NIBLCNGB_01700 326426.Bbr_0189 6.7e-62 243.0 Bifidobacteriales Bacteria 2II0W@201174,4D0VC@85004,COG1942@1,COG1942@2 NA|NA|NA S Macrophage migration inhibitory factor (MIF) NIBLCNGB_01701 326426.Bbr_0190 8.4e-96 356.3 Bifidobacteriales Bacteria 2HZBR@201174,4CZM6@85004,COG2246@1,COG2246@2 NA|NA|NA S GtrA-like protein NIBLCNGB_01702 326426.Bbr_0191 9.7e-248 862.4 Bifidobacteriales Bacteria 2GKMQ@201174,4CZ6D@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily NIBLCNGB_01703 326426.Bbr_0192 7.5e-123 446.4 Bifidobacteriales 3.1.3.3,3.1.3.73 ko:K02226,ko:K22305 ko00260,ko00680,ko00860,ko01100,ko01120,ko01130,map00260,map00680,map00860,map01100,map01120,map01130 M00122 R00582,R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMXF@201174,4CZ0Z@85004,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family NIBLCNGB_01704 326426.Bbr_0193 2.8e-118 431.8 Bifidobacteriales Bacteria 2BR5C@1,2I8T9@201174,32K3E@2,4CZ8U@85004 NA|NA|NA NIBLCNGB_01705 326426.Bbr_0194 5.5e-60 236.9 Bifidobacteriales 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNMK@201174,4D0CD@85004,COG2706@1,COG2706@2 NA|NA|NA G Lactonase, 7-bladed beta-propeller NIBLCNGB_01706 326426.Bbr_0194 1.3e-150 538.9 Bifidobacteriales 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNMK@201174,4D0CD@85004,COG2706@1,COG2706@2 NA|NA|NA G Lactonase, 7-bladed beta-propeller NIBLCNGB_01707 326426.Bbr_0195 6e-151 540.8 Bifidobacteriales Bacteria 2IQHK@201174,4D0Q2@85004,COG3152@1,COG3152@2 NA|NA|NA S Protein of unknown function (DUF805) NIBLCNGB_01709 326426.Bbr_0196 4.7e-293 1013.1 Bifidobacteriales gltX GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 iNJ661.Rv2992c Bacteria 2GJJS@201174,4CZHK@85004,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) NIBLCNGB_01712 762211.BSTEL_1797 2.1e-31 141.4 Bifidobacteriales Bacteria 2GISN@201174,4D0EV@85004,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase, N-terminal SAM-like domain NIBLCNGB_01713 762211.BSTEL_1797 1.9e-22 111.7 Bifidobacteriales Bacteria 2GISN@201174,4D0EV@85004,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase, N-terminal SAM-like domain NIBLCNGB_01715 326426.Bbr_0221 0.0 1112.8 Bifidobacteriales efeU_1 ko:K07243 ko00000,ko02000 2.A.108.1,2.A.108.2 Bacteria 2GJ22@201174,4D01C@85004,COG0672@1,COG0672@2 NA|NA|NA P Iron permease FTR1 family NIBLCNGB_01716 326426.Bbr_0222 2.8e-99 368.2 Bifidobacteriales tpd ko:K07230 ko00000,ko02000 2.A.108.2.10,2.A.108.2.4,2.A.108.2.9 Bacteria 2GNAD@201174,4CZCG@85004,COG3470@1,COG3470@2 NA|NA|NA P Fe2+ transport protein NIBLCNGB_01717 326426.Bbr_0223 7.7e-233 812.8 Bifidobacteriales Bacteria 2GMS6@201174,4CZ19@85004,COG4393@1,COG4393@2 NA|NA|NA S Predicted membrane protein (DUF2318) NIBLCNGB_01718 326426.Bbr_0224 2e-220 771.5 Bifidobacteriales macB_2 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2I91N@201174,4CZGK@85004,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease NIBLCNGB_01719 326426.Bbr_0225 1.7e-196 692.2 Bifidobacteriales Z012_06715 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GIRW@201174,4CZEZ@85004,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family NIBLCNGB_01720 216816.GS08_01100 4.5e-146 523.9 Bifidobacteriales macB ko:K02003,ko:K09810 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 Bacteria 2GK3I@201174,4CYTA@85004,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein NIBLCNGB_01721 326426.Bbr_0227 1.7e-67 262.3 Bifidobacteriales ko:K03612 ko00000 Bacteria 2IQ4E@201174,4D0YM@85004,COG3976@1,COG3976@2 NA|NA|NA S FMN_bind NIBLCNGB_01722 326426.Bbr_0228 7.1e-101 373.2 Bifidobacteriales Bacteria 2HZI8@201174,4D0IS@85004,COG1309@1,COG1309@2 NA|NA|NA K Psort location Cytoplasmic, score 8.87 NIBLCNGB_01723 326426.Bbr_0229 3.7e-304 1050.4 Bifidobacteriales pip ko:K01421 ko00000 Bacteria 2GKEM@201174,4CZ2A@85004,COG1511@1,COG1511@2 NA|NA|NA S YhgE Pip domain protein NIBLCNGB_01724 326426.Bbr_0230 0.0 1271.9 Bifidobacteriales pip ko:K01421 ko00000 Bacteria 2GKEM@201174,4CZ9R@85004,COG1511@1,COG1511@2 NA|NA|NA S YhgE Pip domain protein NIBLCNGB_01725 326426.Bbr_0231 5.5e-253 879.8 Bifidobacteriales Bacteria 2IBSV@201174,4D05G@85004,COG4905@1,COG4905@2 NA|NA|NA S Putative ABC-transporter type IV NIBLCNGB_01726 326426.Bbr_0232 1.5e-272 944.9 Bifidobacteriales gnd GO:0003674,GO:0003824,GO:0004616,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019520,GO:0019521,GO:0019637,GO:0019682,GO:0019693,GO:0019752,GO:0032787,GO:0034641,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046177,GO:0046395,GO:0046483,GO:0046496,GO:0046983,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072329,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 iECS88_1305.ECS88_2128,iECW_1372.ECW_m2189,iEKO11_1354.EKO11_1765,iPC815.YPO1541,iWFL_1372.ECW_m2189 Bacteria 2GJ2J@201174,4CZFG@85004,COG0362@1,COG0362@2 NA|NA|NA H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH NIBLCNGB_01727 326426.Bbr_0233 1.3e-140 505.8 Bifidobacteriales pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31,3.5.99.6 ko:K01057,ko:K02003,ko:K02564 ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008,M00258 R00765,R02035 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1 Bacteria 2GMQ2@201174,4CZRG@85004,COG0363@1,COG0363@2 NA|NA|NA G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase NIBLCNGB_01728 326426.Bbr_0234 3.7e-193 680.6 Bifidobacteriales opcA Bacteria 2GJ1H@201174,4CZI4@85004,COG3429@1,COG3429@2 NA|NA|NA G Glucose-6-phosphate dehydrogenase subunit NIBLCNGB_01729 326426.Bbr_0235 3.5e-304 1050.0 Bifidobacteriales zwf 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 iIT341.HP1101 Bacteria 2GISI@201174,4CYQM@85004,COG0364@1,COG0364@2 NA|NA|NA G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone NIBLCNGB_01730 326426.Bbr_0236 2.4e-291 1007.7 Bifidobacteriales 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 2HZMP@201174,4D0YE@85004,COG2367@1,COG2367@2 NA|NA|NA V Beta-lactamase enzyme family NIBLCNGB_01732 326426.Bbr_0237 4.6e-301 1039.6 Bifidobacteriales pepD ko:K08659 ko00000,ko01000,ko01002 Bacteria 2GM80@201174,4CYT0@85004,COG4690@1,COG4690@2 NA|NA|NA E Peptidase family C69 NIBLCNGB_01733 326426.Bbr_0238 1.1e-197 695.7 Bifidobacteriales XK27_01805 Bacteria 2GMDK@201174,4CZIS@85004,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase like family 2 NIBLCNGB_01734 326426.Bbr_0239 1e-151 542.7 Bifidobacteriales icaR Bacteria 2GMBW@201174,4CYUD@85004,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family NIBLCNGB_01735 326426.Bbr_0240 2.9e-171 608.2 Bifidobacteriales ftsY GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 2GJQH@201174,4CZZX@85004,COG0552@1,COG0552@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) NIBLCNGB_01736 326426.Bbr_0241 1e-227 795.8 Bifidobacteriales amt ko:K03320 ko00000,ko02000 1.A.11 Bacteria 2GIZK@201174,4CZA0@85004,COG0004@1,COG0004@2 NA|NA|NA U Ammonium Transporter Family NIBLCNGB_01737 1435051.BMOU_1470 1.5e-53 215.3 Bifidobacteriales glnB ko:K04751 ko02020,map02020 ko00000,ko00001 Bacteria 2IKN1@201174,4D0VD@85004,COG0347@1,COG0347@2 NA|NA|NA K Nitrogen regulatory protein P-II NIBLCNGB_01738 326426.Bbr_0243 0.0 1234.6 Bifidobacteriales 2.7.7.19,2.7.7.59 ko:K00970,ko:K00990 ko02020,ko03018,map02020,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2GMKT@201174,4D07P@85004,COG2844@1,COG2844@2 NA|NA|NA O Nucleotidyltransferase domain NIBLCNGB_01739 326426.Bbr_0244 1.6e-236 825.1 Bifidobacteriales dinF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03327 ko00000,ko02000 2.A.66.1 Bacteria 2GJE3@201174,4CZ75@85004,COG0534@1,COG0534@2 NA|NA|NA V MatE NIBLCNGB_01740 216816.GS08_01205 2.1e-250 871.3 Bifidobacteriales dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 2GKXQ@201174,4CYY3@85004,COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication NIBLCNGB_01741 326426.Bbr_0246 1.7e-257 894.8 Bifidobacteriales murD 3.4.21.10,6.3.2.13,6.3.2.9 ko:K01317,ko:K01925,ko:K01928,ko:K01932 ko00300,ko00471,ko00550,ko01100,map00300,map00471,map00550,map01100 R02783,R02788 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01002,ko01011,ko04131 Bacteria 2GK18@201174,4CYTP@85004,COG0771@1,COG0771@2 NA|NA|NA M Domain of unknown function (DUF1727) NIBLCNGB_01742 326426.Bbr_0247 1.1e-141 509.2 Bifidobacteriales cobQ ko:K07009 ko00000 iSB619.SA_RS09800 Bacteria 2GKPV@201174,4CZJ1@85004,COG3442@1,COG3442@2 NA|NA|NA S CobB/CobQ-like glutamine amidotransferase domain NIBLCNGB_01743 326426.Bbr_0248 5.5e-38 163.3 Bifidobacteriales Bacteria 2GS3M@201174,4D1FE@85004,COG3937@1,COG3937@2 NA|NA|NA S granule-associated protein NIBLCNGB_01744 326426.Bbr_0249 0.0 1144.8 Bifidobacteriales ubiB ko:K03688 ko00000 Bacteria 2GJQ6@201174,4CZ45@85004,COG0661@1,COG0661@2 NA|NA|NA S ABC1 family NIBLCNGB_01745 158787.BSCA_0644 8.7e-85 319.7 Bifidobacteriales ko:K02529 ko00000,ko03000 Bacteria 2GJV7@201174,4CZND@85004,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding protein domain NIBLCNGB_01746 762211.BSTEL_1934 1.3e-275 955.3 Bifidobacteriales 3.2.1.185 ko:K09955,ko:K18205 ko00000,ko01000 GH127 Bacteria 2GM60@201174,4CYSU@85004,COG3533@1,COG3533@2 NA|NA|NA S Beta-L-arabinofuranosidase, GH127 NIBLCNGB_01747 326426.Bbr_0252 2.2e-154 551.6 Bifidobacteriales yggS ko:K06997 ko00000 Bacteria 2GMRJ@201174,4CZUY@85004,COG0325@1,COG0325@2 NA|NA|NA S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis NIBLCNGB_01748 216816.GS08_01250 1.3e-187 662.1 Bifidobacteriales prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ9S@201174,4CZPM@85004,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) NIBLCNGB_01749 216816.GS08_01260 4.6e-48 196.8 Bifidobacteriales rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904 ko:K02990 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2IQHD@201174,4D10X@85004,COG0360@1,COG0360@2 NA|NA|NA J Binds together with S18 to 16S ribosomal RNA NIBLCNGB_01750 326426.Bbr_0255 4e-76 291.2 Bifidobacteriales ssb1 ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 2GMM3@201174,4CZ5V@85004,COG0629@1,COG0629@2 NA|NA|NA L Single-stranded DNA-binding protein NIBLCNGB_01751 326426.Bbr_0256 2e-36 157.9 Bifidobacteriales rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963,ko:K03111,ko:K15125 ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133 M00178 br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400 Bacteria 2IQ92@201174,4D103@85004,COG0238@1,COG0238@2 NA|NA|NA J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit NIBLCNGB_01752 326426.Bbr_0257 2.7e-71 274.6 Bifidobacteriales rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKX7@201174,4D0P9@85004,COG0359@1,COG0359@2 NA|NA|NA J Binds to the 23S rRNA NIBLCNGB_01754 326426.Bbr_0267 4.5e-116 424.1 Bifidobacteriales gla ko:K02440 ko00000,ko02000 1.A.8.1,1.A.8.2 iHN637.CLJU_RS07630 Bacteria 2GKK3@201174,4CZ7F@85004,COG0580@1,COG0580@2 NA|NA|NA U Belongs to the MIP aquaporin (TC 1.A.8) family NIBLCNGB_01755 326426.Bbr_0268 0.0 1531.5 Bifidobacteriales pacS GO:0000041,GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0016020,GO:0030001,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0071944 1.9.3.1,3.6.3.54 ko:K02275,ko:K17686 ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016 M00155 R00081,R00086 RC00002,RC00016 ko00000,ko00001,ko00002,ko01000 3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 2GIRF@201174,4CZ24@85004,COG2217@1,COG2217@2,COG4633@1,COG4633@2 NA|NA|NA P E1-E2 ATPase NIBLCNGB_01756 326426.Bbr_0269 3.3e-43 180.6 Bifidobacteriales csoR GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0042221,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0046688,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K21600 ko00000,ko03000 Bacteria 2IQAC@201174,4D1A2@85004,COG1937@1,COG1937@2 NA|NA|NA S Metal-sensitive transcriptional repressor NIBLCNGB_01757 326426.Bbr_0270 3.5e-210 737.6 Bifidobacteriales rmuC ko:K09760 ko00000 Bacteria 2GP4U@201174,4CZA5@85004,COG1322@1,COG1322@2 NA|NA|NA S RmuC family NIBLCNGB_01758 326426.Bbr_0271 1.3e-108 399.1 Bifidobacteriales pyrE 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 iJN678.umpS Bacteria 2HZDS@201174,4CZZ6@85004,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) NIBLCNGB_01759 326426.Bbr_0272 1.5e-169 602.1 Bifidobacteriales spoU 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 2GM1A@201174,4CZE8@85004,COG0566@1,COG0566@2 NA|NA|NA J RNA methyltransferase TrmH family NIBLCNGB_01760 326426.Bbr_0273 5.4e-167 593.6 Bifidobacteriales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJDP@201174,4D00Y@85004,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter NIBLCNGB_01761 326426.Bbr_0274 2.9e-177 627.9 Bifidobacteriales Bacteria 2DRNP@1,2I2HC@201174,33CDT@2,4D2VI@85004 NA|NA|NA NIBLCNGB_01762 326426.Bbr_0275 2.5e-160 571.2 Bifidobacteriales Bacteria 2ICPH@201174,4CZJ7@85004,COG5340@1,COG5340@2 NA|NA|NA K Psort location Cytoplasmic, score NIBLCNGB_01763 398513.BBNG_01427 2.7e-50 204.9 Bifidobacteriales gatC GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 2IQJN@201174,4D10U@85004,COG0721@1,COG0721@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) NIBLCNGB_01764 326426.Bbr_0277 2.8e-285 987.3 Bifidobacteriales gatA GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 2GJK5@201174,4CZ1X@85004,COG0154@1,COG0154@2 NA|NA|NA F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) NIBLCNGB_01765 326426.Bbr_0278 1.3e-282 978.4 Bifidobacteriales gatB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 2GJJH@201174,4CYUY@85004,COG0064@1,COG0064@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) NIBLCNGB_01766 326426.Bbr_0279 4e-195 687.2 Bifidobacteriales 2.3.1.57 ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 M00135 R01154 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 2I2GV@201174,4CYPW@85004,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain NIBLCNGB_01767 216816.GS08_01350 3.3e-52 210.7 Bifidobacteriales GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2AFXT@1,2IKPZ@201174,3161G@2,4D0UV@85004 NA|NA|NA S Protein of unknown function (DUF2469) NIBLCNGB_01769 326426.Bbr_0281 0.0 1115.9 Bifidobacteriales 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 Bacteria 2HZ9K@201174,4CZ3Z@85004,COG1232@1,COG1232@2 NA|NA|NA H Flavin containing amine oxidoreductase NIBLCNGB_01770 326426.Bbr_0282 8.9e-281 972.6 Bifidobacteriales rho GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Bacteria 2GIWY@201174,4CZ2Z@85004,COG1158@1,COG1158@2 NA|NA|NA K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template NIBLCNGB_01771 1437609.BCAL_1765 5.9e-140 503.8 Bifidobacteriales pabC 2.6.1.42,4.1.3.38 ko:K00826,ko:K02619 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R05553,R10991 RC00006,RC00036,RC01843,RC02148 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GN5Z@201174,4CZJG@85004,COG0115@1,COG0115@2 NA|NA|NA EH Amino-transferase class IV NIBLCNGB_01772 326426.Bbr_0287 2.3e-63 248.1 Bifidobacteriales tyrA 5.4.99.5 ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 Bacteria 2IQ46@201174,4D12A@85004,COG1605@1,COG1605@2 NA|NA|NA E Chorismate mutase type II NIBLCNGB_01773 326426.Bbr_0288 0.0 1127.1 Bifidobacteriales ko:K01421,ko:K21449 ko00000,ko02000 1.B.40.2 Bacteria 2I9PN@201174,4CZC2@85004,COG1511@1,COG1511@2 NA|NA|NA S domain protein NIBLCNGB_01774 326426.Bbr_0289 0.0 1877.8 Bifidobacteriales valS 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GK8H@201174,4CYVG@85004,COG0525@1,COG0525@2 NA|NA|NA J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner NIBLCNGB_01775 326426.Bbr_0290 5.8e-283 979.5 Bifidobacteriales ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GM5G@201174,4CYUZ@85004,COG0747@1,COG0747@2 NA|NA|NA E Bacterial extracellular solute-binding proteins, family 5 Middle NIBLCNGB_01776 326426.Bbr_0291 5.7e-126 456.8 Bifidobacteriales nth GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJ01@201174,4CZ31@85004,COG0177@1,COG0177@2 NA|NA|NA L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate NIBLCNGB_01777 326426.Bbr_0292 6.9e-139 500.0 Bifidobacteriales Bacteria 2GJGU@201174,4CZB9@85004,COG0745@1,COG0745@2 NA|NA|NA KT Transcriptional regulatory protein, C terminal NIBLCNGB_01778 326426.Bbr_0293 1.9e-116 425.2 Bifidobacteriales Bacteria 2A0I6@1,2GJ8M@201174,30NNB@2,4D0ZN@85004 NA|NA|NA NIBLCNGB_01779 1437610.BREU_0484 4.5e-87 327.4 Bifidobacteriales mntP Bacteria 2GNBU@201174,4D01X@85004,COG1971@1,COG1971@2 NA|NA|NA P Probably functions as a manganese efflux pump NIBLCNGB_01780 326426.Bbr_0295 4e-92 344.0 Bifidobacteriales ppa GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944 3.6.1.1 ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 iNJ661.Rv3628 Bacteria 2GM7F@201174,4CYWS@85004,COG0221@1,COG0221@2 NA|NA|NA C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions NIBLCNGB_01781 326426.Bbr_0296 0.0 1449.9 Bifidobacteriales glgE 2.4.99.16 ko:K16147 ko00500,ko01100,map00500,map01100 R09994 ko00000,ko00001,ko01000 GH13 Bacteria 2GJKR@201174,4CZSK@85004,COG0366@1,COG0366@2 NA|NA|NA G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB NIBLCNGB_01782 326426.Bbr_0297 0.0 1231.9 Bifidobacteriales Bacteria 2H7AK@201174,4CZMA@85004,COG5624@1,COG5624@2 NA|NA|NA K RNA polymerase II activating transcription factor binding NIBLCNGB_01785 1437608.BBIA_1847 5.1e-11 74.3 Bifidobacteriales Bacteria 2ADV9@1,2HDCD@201174,313M5@2,4D2QB@85004 NA|NA|NA NIBLCNGB_01787 1416759.AYMR01000009_gene3000 1.1e-39 170.6 Microbacteriaceae Bacteria 2HT61@201174,4FRXS@85023,COG0330@1,COG0330@2 NA|NA|NA O prohibitin homologues NIBLCNGB_01792 904144.AEJD01000006_gene414 2.6e-49 201.8 Bifidobacteriales ssb1 ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 2GMM3@201174,4CZ5V@85004,COG0629@1,COG0629@2 NA|NA|NA L Single-stranded DNA-binding protein NIBLCNGB_01793 1435051.BMOU_0254 4.1e-08 64.7 Bifidobacteriales Bacteria 2BEW9@1,2HEFE@201174,328MX@2,4D2QV@85004 NA|NA|NA NIBLCNGB_01796 1437608.BBIA_2172 6e-30 137.1 Bifidobacteriales Bacteria 2GQKB@201174,4D1JQ@85004,COG1403@1,COG1403@2 NA|NA|NA V HNH endonuclease NIBLCNGB_01797 1437608.BBIA_2171 4.4e-43 181.4 Bifidobacteriales ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2IM4T@201174,4D15Z@85004,COG1949@1,COG1949@2 NA|NA|NA A 3'-to-5' exoribonuclease specific for small oligoribonucleotides NIBLCNGB_01798 1437608.BBIA_2170 2e-40 171.8 Actinobacteria Bacteria 2E5GW@1,2GX64@201174,3308F@2 NA|NA|NA S Protein of unknwon function (DUF3310) NIBLCNGB_01805 1341695.BBOMB_1048 2.9e-18 99.4 Bifidobacteriales Bacteria 2AZUG@1,2GQ7F@201174,31S3T@2,4D1BR@85004 NA|NA|NA NIBLCNGB_01807 1437608.BBIA_2158 4.2e-35 154.1 Bifidobacteriales Bacteria 2GVS5@201174,4D1MN@85004,COG1403@1,COG1403@2 NA|NA|NA L HNH endonuclease NIBLCNGB_01808 1273125.Rrhod_0724 3e-07 61.2 Nocardiaceae Bacteria 2AR8S@1,2HCA2@201174,31GIM@2,4G80B@85025 NA|NA|NA NIBLCNGB_01809 1437608.BBIA_2156 5.6e-240 836.6 Bifidobacteriales Bacteria 2IB7D@201174,4CZEW@85004,COG4626@1,COG4626@2 NA|NA|NA S Terminase NIBLCNGB_01810 1437608.BBIA_2155 9.6e-174 616.7 Bifidobacteriales Bacteria 2C9AC@1,2I2HE@201174,2Z839@2,4CZJA@85004 NA|NA|NA S Phage portal protein, SPP1 Gp6-like NIBLCNGB_01811 1437605.BACT_0499 1.7e-88 333.2 Bifidobacteriales Bacteria 2DM1N@1,2IRH6@201174,31BIG@2,4D0UB@85004 NA|NA|NA NIBLCNGB_01812 1437608.BBIA_1439 2.8e-12 77.8 Bifidobacteriales Bacteria 2BKG9@1,2H18E@201174,32EX3@2,4D1SN@85004 NA|NA|NA NIBLCNGB_01813 1437608.BBIA_2153 1.3e-24 119.8 Bifidobacteriales Bacteria 2EU2I@1,2IRRZ@201174,33MJH@2,4D1BP@85004 NA|NA|NA NIBLCNGB_01814 1437608.BBIA_2152 2.7e-147 528.1 Bifidobacteriales Bacteria 2I2HF@201174,4D086@85004,COG0577@1,COG0577@2 NA|NA|NA V Phage capsid family NIBLCNGB_01816 1437608.BBIA_2150 1.3e-46 192.6 Bifidobacteriales Bacteria 2EEUJ@1,2IRIW@201174,338N2@2,4D1FY@85004 NA|NA|NA S Phage protein Gp19/Gp15/Gp42 NIBLCNGB_01817 1437608.BBIA_2149 1e-30 139.4 Bifidobacteriales Bacteria 2ENTG@1,2GSYZ@201174,33GEN@2,4D1GG@85004 NA|NA|NA NIBLCNGB_01818 1437609.BCAL_0179 2.6e-08 64.7 Bifidobacteriales Bacteria 2BEER@1,2HDXV@201174,3285Y@2,4D2JP@85004 NA|NA|NA NIBLCNGB_01819 1437608.BBIA_2147 1.3e-18 99.4 Bifidobacteriales Bacteria 2B5F1@1,2GW7I@201174,31Y9I@2,4D1J8@85004 NA|NA|NA NIBLCNGB_01820 1437608.BBIA_2146 3.1e-59 235.0 Bifidobacteriales eae GO:0008150,GO:0009405,GO:0044419,GO:0051704 ko:K12790,ko:K13735 ko05100,ko05130,map05100,map05130 ko00000,ko00001 Bacteria 2GUYJ@201174,4D1EW@85004,COG5492@1,COG5492@2 NA|NA|NA N domain, Protein NIBLCNGB_01821 1437608.BBIA_2145 8.1e-30 136.3 Bifidobacteriales Bacteria 2EQ7M@1,2GZRV@201174,33HTV@2,4D1SP@85004 NA|NA|NA NIBLCNGB_01822 1437608.BBIA_2144 2.2e-29 135.2 Bifidobacteriales Bacteria 2BNR1@1,2HZZJ@201174,32HED@2,4D2DU@85004 NA|NA|NA NIBLCNGB_01823 1437609.BCAL_0193 1.4e-83 318.2 Bifidobacteriales Bacteria 2H75F@201174,4CZ1P@85004,COG3941@1,COG3941@2,COG5412@1,COG5412@2 NA|NA|NA NT phage tail tape measure protein NIBLCNGB_01824 1437608.BBIA_2142 1.5e-69 269.6 Bifidobacteriales Bacteria 2GSFE@201174,4D1EK@85004,COG4722@1,COG4722@2 NA|NA|NA S phage tail NIBLCNGB_01825 1437608.BBIA_2552 2.3e-224 786.2 Bifidobacteriales Bacteria 2GKYX@201174,4D0B9@85004,COG4926@1,COG4926@2 NA|NA|NA S Prophage endopeptidase tail NIBLCNGB_01828 398513.BBNG_00862 5.5e-09 66.6 Bifidobacteriales Bacteria 2AR26@1,2IF4V@201174,31GB5@2,4D0GW@85004 NA|NA|NA NIBLCNGB_01829 702459.BBPR_0927 1.5e-11 76.3 Bifidobacteriales Bacteria 2AR26@1,2IF4V@201174,31GB5@2,4D0GW@85004 NA|NA|NA NIBLCNGB_01830 1680.BADO_1222 6.6e-133 481.1 Bacteria Bacteria 2DKX6@1,30QMZ@2 NA|NA|NA NIBLCNGB_01831 1680.BADO_1221 2.4e-85 322.8 Bacteria ko:K15342 ko00000,ko02048,ko03400 Bacteria COG3344@1,COG3344@2 NA|NA|NA L reverse transcriptase NIBLCNGB_01833 158787.BSCA_0721 9.4e-18 96.3 Bifidobacteriales Bacteria 2BJPU@1,2GZ2E@201174,32E1F@2,4D1PK@85004 NA|NA|NA NIBLCNGB_01834 158787.BSCA_0886 1.7e-104 386.3 Bifidobacteriales ko:K07273,ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 2I2GA@201174,4D07F@85004,COG1388@1,COG1388@2,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 NIBLCNGB_01835 326426.Bbr_0299 8.2e-28 129.4 Bifidobacteriales Bacteria 2EK5K@1,2GSM4@201174,33DW0@2,4D1J2@85004 NA|NA|NA S Putative phage holin Dp-1 NIBLCNGB_01836 702459.BBPR_1656 7.2e-38 162.9 Bifidobacteriales Bacteria 2E3TC@1,2GU2H@201174,32DPP@2,4D1HW@85004 NA|NA|NA NIBLCNGB_01837 1437610.BREU_0488 2.4e-43 181.0 Bifidobacteriales ko:K09803 ko00000 Bacteria 2GW9X@201174,4D1SS@85004,COG2929@1,COG2929@2 NA|NA|NA S Ribonuclease toxin, BrnT, of type II toxin-antitoxin system NIBLCNGB_01838 326426.Bbr_0321 7e-94 350.5 Bifidobacteriales Bacteria 2IH6A@201174,4CZ62@85004,COG4974@1,COG4974@2 NA|NA|NA L Phage integrase family NIBLCNGB_01840 326426.Bbr_0322 1.6e-207 728.4 Bifidobacteriales metAA GO:0003674,GO:0003824,GO:0008374,GO:0008899,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0881 Bacteria 2GK5E@201174,4CZRK@85004,COG1897@1,COG1897@2 NA|NA|NA E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine NIBLCNGB_01841 326426.Bbr_0323 1.1e-144 519.2 Bifidobacteriales atpB ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 Bacteria 2H3PR@201174,4CYZD@85004,COG0356@1,COG0356@2 NA|NA|NA C it plays a direct role in the translocation of protons across the membrane NIBLCNGB_01842 356829.BITS_0605 1.7e-29 134.8 Bifidobacteriales atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2GQI6@201174,4D16J@85004,COG0636@1,COG0636@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation NIBLCNGB_01843 326426.Bbr_0325 4.9e-61 240.7 Bifidobacteriales atpF ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2GJS4@201174,4CYY5@85004,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) NIBLCNGB_01844 326426.Bbr_0326 2.2e-151 541.6 Bifidobacteriales atpH ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2GMJ5@201174,4CZ9V@85004,COG0712@1,COG0712@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation NIBLCNGB_01845 326426.Bbr_0327 1.3e-309 1068.1 Bifidobacteriales atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 Bacteria 2GJRJ@201174,4CZI7@85004,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit NIBLCNGB_01846 326426.Bbr_0328 6.1e-163 580.1 Bifidobacteriales atpG GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138 Bacteria 2GJ7Q@201174,4CYVJ@85004,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex NIBLCNGB_01847 326426.Bbr_0329 2.1e-282 977.6 Bifidobacteriales atpD GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 Bacteria 2GIY6@201174,4CZGY@85004,COG0055@1,COG0055@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits NIBLCNGB_01848 326426.Bbr_0330 9.4e-49 199.1 Bifidobacteriales atpC GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2HZPJ@201174,4D16F@85004,COG0355@1,COG0355@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane NIBLCNGB_01849 326426.Bbr_0331 1.2e-129 469.2 Bifidobacteriales nucS ko:K07503 ko00000,ko01000 Bacteria 2GIYB@201174,4CYXA@85004,COG1637@1,COG1637@2 NA|NA|NA L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures NIBLCNGB_01850 326426.Bbr_0332 3.6e-158 564.3 Bifidobacteriales fkbB 5.2.1.8 ko:K01802 ko00000,ko01000 Bacteria 2GJK2@201174,4CZEF@85004,COG0545@1,COG0545@2 NA|NA|NA M FKBP-type peptidyl-prolyl cis-trans isomerase NIBLCNGB_01851 326426.Bbr_0333 1.8e-186 658.7 Bifidobacteriales Bacteria 2DMQ0@1,2IA0N@201174,32SYI@2,4CYQ0@85004 NA|NA|NA NIBLCNGB_01852 326426.Bbr_0334 6.6e-179 633.3 Bifidobacteriales Bacteria 28PR0@1,2GNNZ@201174,2ZCCY@2,4CYX7@85004 NA|NA|NA NIBLCNGB_01853 326426.Bbr_0335 1.1e-164 585.9 Bifidobacteriales trxA2 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K03671,ko:K05838 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 2GJ7B@201174,4CZHU@85004,COG3118@1,COG3118@2 NA|NA|NA O Tetratricopeptide repeat NIBLCNGB_01854 326426.Bbr_0336 4.5e-117 427.2 Bifidobacteriales cyaA GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0050355 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 2GWD8@201174,4CZKD@85004,COG2954@1,COG2954@2 NA|NA|NA S CYTH NIBLCNGB_01857 326426.Bbr_0338 1.4e-63 248.8 Bifidobacteriales psp1 3.5.99.10 ko:K09022 R11098,R11099 RC03275,RC03354 ko00000,ko01000 Bacteria 2IFCR@201174,4D0QD@85004,COG0251@1,COG0251@2 NA|NA|NA J Endoribonuclease L-PSP NIBLCNGB_01858 326426.Bbr_0339 7.4e-188 662.9 Bifidobacteriales plsC2 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GKVA@201174,4CZG0@85004,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases NIBLCNGB_01859 326426.Bbr_0340 2.7e-180 637.9 Bifidobacteriales gpsA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 Bacteria 2GJSD@201174,4CZHP@85004,COG0240@1,COG0240@2 NA|NA|NA I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NIBLCNGB_01860 326426.Bbr_0341 7e-228 796.2 Bifidobacteriales ddl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008716,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016874,GO:0016879,GO:0016881,GO:0044424,GO:0044444,GO:0044464,GO:0050896 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iAF1260.b0381,iB21_1397.B21_00332,iBWG_1329.BWG_0265,iE2348C_1286.E2348C_0317,iEC042_1314.EC042_0413,iEC55989_1330.EC55989_0386,iECBD_1354.ECBD_3283,iECB_1328.ECB_00328,iECDH10B_1368.ECDH10B_0338,iECDH1ME8569_1439.ECDH1ME8569_0367,iECD_1391.ECD_00328,iECH74115_1262.ECH74115_0453,iECIAI1_1343.ECIAI1_0377,iECIAI39_1322.ECIAI39_0301,iECO103_1326.ECO103_0356,iECO111_1330.ECO111_0411,iECO26_1355.ECO26_0414,iECSE_1348.ECSE_0401,iECSP_1301.ECSP_0441,iECs_1301.ECs0431,iETEC_1333.ETEC_0434,iEcDH1_1363.EcDH1_3227,iEcE24377_1341.EcE24377A_0406,iEcHS_1320.EcHS_A0447,iEcSMS35_1347.EcSMS35_0410,iEcolC_1368.EcolC_3251,iJO1366.b0381,iJR904.b0381,iSF_1195.SF0232,iSFxv_1172.SFxv_0245,iS_1188.S0254,iUMNK88_1353.UMNK88_429,iY75_1357.Y75_RS01965,iZ_1308.Z0477 Bacteria 2GITC@201174,4CZ1R@85004,COG1181@1,COG1181@2 NA|NA|NA F Belongs to the D-alanine--D-alanine ligase family NIBLCNGB_01861 326426.Bbr_0342 1.1e-217 762.3 Bifidobacteriales ko:K02055 ko02024,map02024 M00193 ko00000,ko00001,ko00002,ko02000 3.A.1.11 Bacteria 2GJFH@201174,4CZHC@85004,COG1840@1,COG1840@2 NA|NA|NA P Bacterial extracellular solute-binding protein NIBLCNGB_01862 326426.Bbr_0343 9.9e-161 572.8 Bifidobacteriales ko:K02054 ko02024,map02024 M00193 ko00000,ko00001,ko00002,ko02000 3.A.1.11 Bacteria 2GNDF@201174,4CZHE@85004,COG4132@1,COG4132@2 NA|NA|NA U Binding-protein-dependent transport system inner membrane component NIBLCNGB_01863 326426.Bbr_0344 1.4e-151 542.3 Bifidobacteriales ko:K02053 ko02024,map02024 M00193 ko00000,ko00001,ko00002,ko02000 3.A.1.11 Bacteria 2GM0E@201174,4CZ2N@85004,COG1177@1,COG1177@2 NA|NA|NA U Binding-protein-dependent transport system inner membrane component NIBLCNGB_01864 326426.Bbr_0345 1.5e-239 835.1 Bifidobacteriales 3.6.3.30 ko:K02010,ko:K02052 ko02010,ko02024,map02010,map02024 M00190,M00193 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11 Bacteria 2GJCM@201174,4CZPE@85004,COG3842@1,COG3842@2 NA|NA|NA E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system NIBLCNGB_01865 326426.Bbr_0346 1.2e-186 659.1 Bifidobacteriales Bacteria 2I3DW@201174,4CZJZ@85004,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity NIBLCNGB_01866 326426.Bbr_0347 1.7e-137 495.4 Bifidobacteriales Bacteria 2GZI1@201174,4CZ0A@85004,COG0668@1,COG0668@2 NA|NA|NA M Mechanosensitive ion channel NIBLCNGB_01867 326426.Bbr_0348 8.6e-273 945.7 Bifidobacteriales aspA 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 R00490 RC00316,RC02799 ko00000,ko00001,ko01000 Bacteria 2I2HG@201174,4CZ6N@85004,COG1027@1,COG1027@2 NA|NA|NA E Fumarase C C-terminus NIBLCNGB_01868 158787.BSCA_0159 9.3e-11 72.0 Bifidobacteriales Bacteria 2GX1N@201174,4D2D5@85004,COG3293@1,COG3293@2 NA|NA|NA L Transposase DDE domain NIBLCNGB_01869 326426.Bbr_0349 5.7e-133 480.3 Bifidobacteriales ko:K07090 ko00000 Bacteria 2I5VT@201174,4D23D@85004,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE NIBLCNGB_01870 326426.Bbr_0350 2.8e-262 910.6 Bifidobacteriales aslB GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:1901564 ko:K06871 ko00000 Bacteria 2HZTM@201174,4D1Q0@85004,COG0641@1,COG0641@2 NA|NA|NA C Iron-sulfur cluster-binding domain NIBLCNGB_01871 326426.Bbr_0351 3.8e-193 680.6 Bifidobacteriales Bacteria 2GJ5Q@201174,4D041@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor NIBLCNGB_01872 326426.Bbr_0352 2.1e-306 1057.4 Bifidobacteriales Z012_09690 Bacteria 2GJ8H@201174,4D246@85004,COG3119@1,COG3119@2 NA|NA|NA P Domain of unknown function (DUF4976) NIBLCNGB_01873 326426.Bbr_0353 4.1e-264 916.8 Bifidobacteriales ko:K02027,ko:K10240 ko02010,map02010 M00206,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.23 Bacteria 2GJIP@201174,4CZWR@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_01874 326426.Bbr_0354 2.9e-165 587.8 Bifidobacteriales malC ko:K02025,ko:K10118,ko:K10241,ko:K15771 ko02010,map02010 M00196,M00206,M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.23,3.A.1.1.28 Bacteria 2GMTW@201174,4CZW4@85004,COG1175@1,COG1175@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component NIBLCNGB_01875 326426.Bbr_0355 1.6e-177 628.6 Bifidobacteriales ko:K02026 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GJPZ@201174,4CZTQ@85004,COG0395@1,COG0395@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component NIBLCNGB_01876 326426.Bbr_0356 2.2e-237 827.8 Bifidobacteriales ko:K07133 ko00000 Bacteria 2I96U@201174,4CZD7@85004,COG1373@1,COG1373@2 NA|NA|NA S AAA domain NIBLCNGB_01877 78344.BIGA_0350 4.3e-40 170.6 Bifidobacteriales Bacteria 2GM8F@201174,4D023@85004,COG3328@1,COG3328@2 NA|NA|NA L Transposase, Mutator family NIBLCNGB_01878 216816.GS08_01565 1.3e-106 392.5 Bifidobacteriales Bacteria 2I8SX@201174,4CZXQ@85004,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family NIBLCNGB_01879 326426.Bbr_0358 2.3e-256 891.0 Bifidobacteriales MA20_36090 Bacteria 2GMT6@201174,4CZ4Q@85004,COG1073@1,COG1073@2 NA|NA|NA S Psort location Cytoplasmic, score 8.87 NIBLCNGB_01880 326426.Bbr_0359 5.4e-89 333.6 Bifidobacteriales ogt GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63,3.2.2.20 ko:K00567,ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2IHXW@201174,4D10F@85004,COG0350@1,COG0350@2 NA|NA|NA L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated NIBLCNGB_01881 326426.Bbr_0360 1.9e-81 308.5 Bifidobacteriales acpS GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.8.7,3.2.1.52 ko:K00997,ko:K01207 ko00520,ko00531,ko00770,ko01100,ko01501,map00520,map00531,map00770,map01100,map01501 M00628 R00022,R01625,R05963,R07809,R07810,R10831 RC00002,RC00049 ko00000,ko00001,ko00002,ko01000 Bacteria 2HZNB@201174,4D10J@85004,COG0736@1,COG0736@2 NA|NA|NA I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein NIBLCNGB_01882 326426.Bbr_0361 1.1e-70 273.5 Bifidobacteriales ams 2.4.1.4,3.2.1.1,5.4.99.16 ko:K05341,ko:K05343 ko00500,ko01100,map00500,map01100 R01557,R01823,R02108,R02112,R11262 RC00028,RC01816 ko00000,ko00001,ko01000 GH13 Bacteria 2GKT9@201174,4CYRW@85004,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain NIBLCNGB_01884 326426.Bbr_0363 4.3e-103 380.6 Bifidobacteriales Bacteria 2C89M@1,2IPVJ@201174,332IE@2,4D133@85004 NA|NA|NA NIBLCNGB_01885 216816.GS08_09350 0.0 1600.1 Bifidobacteriales 1.3.98.1,3.2.1.21 ko:K00226,ko:K05349 ko00240,ko00460,ko00500,ko00940,ko01100,ko01110,map00240,map00460,map00500,map00940,map01100,map01110 M00051 R00026,R01867,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00051,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000 GH3 Bacteria 2GYAW@201174,4D2X8@85004,COG1361@1,COG1361@2 NA|NA|NA M Conserved repeat domain NIBLCNGB_01886 326426.Bbr_0366 1.8e-276 958.0 Bifidobacteriales Bacteria 2GP68@201174,4CZV4@85004,COG4932@1,COG4932@2 NA|NA|NA M LPXTG cell wall anchor motif NIBLCNGB_01888 326426.Bbr_0368 7.2e-86 323.2 Bifidobacteriales Bacteria 2DNNA@1,2ISEY@201174,32Y8E@2,4D1A0@85004 NA|NA|NA NIBLCNGB_01889 326426.Bbr_0369 7.6e-110 403.3 Bifidobacteriales Bacteria 2B37S@1,2IDBE@201174,31VVT@2,4CZJV@85004 NA|NA|NA NIBLCNGB_01890 326426.Bbr_0370 1e-41 175.6 Bifidobacteriales rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQA0@201174,4D10E@85004,COG0184@1,COG0184@2 NA|NA|NA J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome NIBLCNGB_01891 326426.Bbr_0371 0.0 1421.8 Bifidobacteriales pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 2GIT2@201174,4CYSW@85004,COG1185@1,COG1185@2 NA|NA|NA J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction NIBLCNGB_01892 326426.Bbr_0372 2.9e-120 438.0 Bifidobacteriales ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2I7UV@201174,4CZ1C@85004,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein NIBLCNGB_01893 326426.Bbr_0373 4e-26 125.6 Bifidobacteriales macB_7 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GMGJ@201174,4CZ0B@85004,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family NIBLCNGB_01894 326426.Bbr_0374 2.4e-88 331.6 Bifidobacteriales lemA ko:K03744 ko00000 Bacteria 2GPS4@201174,4CZE2@85004,COG1704@1,COG1704@2 NA|NA|NA S LemA family NIBLCNGB_01895 326426.Bbr_0375 0.0 1398.6 Bifidobacteriales Bacteria 2HZD2@201174,4CZV5@85004,COG4907@1,COG4907@2 NA|NA|NA S Predicted membrane protein (DUF2207) NIBLCNGB_01896 1680.BADO_0270 1.4e-10 72.0 Bifidobacteriales Bacteria 2HZD2@201174,4CZV5@85004,COG4907@1,COG4907@2 NA|NA|NA S Predicted membrane protein (DUF2207) NIBLCNGB_01897 326426.Bbr_0376 1.2e-69 269.6 Bifidobacteriales Bacteria 2HZD2@201174,4CZV5@85004,COG4907@1,COG4907@2 NA|NA|NA S Predicted membrane protein (DUF2207) NIBLCNGB_01898 326426.Bbr_0376a 2.1e-12 77.8 Bifidobacteriales Bacteria 29W0J@1,2HBEV@201174,30HIU@2,4D2JK@85004 NA|NA|NA NIBLCNGB_01899 326426.Bbr_0377 4.1e-169 600.5 Bifidobacteriales 1.1.1.65 ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 R01708 RC00116 ko00000,ko00001,ko01000 Bacteria 2GJ6R@201174,4CZB6@85004,COG0667@1,COG0667@2 NA|NA|NA C Oxidoreductase, aldo keto reductase family protein NIBLCNGB_01900 326426.Bbr_0378 2.6e-202 711.1 Bifidobacteriales iunH1 3.2.2.1 ko:K01239,ko:K01250 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 Bacteria 2GP6N@201174,4CZ0Y@85004,COG1957@1,COG1957@2 NA|NA|NA F Inosine-uridine preferring nucleoside hydrolase NIBLCNGB_01901 326426.Bbr_0379 2.2e-108 398.3 Bifidobacteriales rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 ko:K02860 ko00000,ko03009 Bacteria 2GK4I@201174,4D0C6@85004,COG0806@1,COG0806@2 NA|NA|NA J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes NIBLCNGB_01902 1437609.BCAL_0857 1e-34 152.1 Bifidobacteriales CP_0960 GO:0008150,GO:0040007 ko:K06960 ko00000 Bacteria 2IQ4C@201174,4D16Z@85004,COG1837@1,COG1837@2 NA|NA|NA S Belongs to the UPF0109 family NIBLCNGB_01903 326426.Bbr_0381 2.9e-57 228.0 Bifidobacteriales rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2IKU0@201174,4D0PE@85004,COG0228@1,COG0228@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS16 family NIBLCNGB_01904 326426.Bbr_0382 2.7e-204 718.0 Bifidobacteriales Bacteria 2GK2H@201174,4CYS3@85004,COG3021@1,COG3021@2 NA|NA|NA S Endonuclease/Exonuclease/phosphatase family NIBLCNGB_01905 326426.Bbr_0383 6.9e-266 922.9 Bifidobacteriales ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 2GK4R@201174,4CYY1@85004,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY NIBLCNGB_01906 326426.Bbr_0384 2.3e-162 578.2 Bifidobacteriales Bacteria 2H4CC@201174,4CZ1H@85004,COG3965@1,COG3965@2 NA|NA|NA P Cation efflux family NIBLCNGB_01907 326426.Bbr_0385 0.0 1095.5 Bifidobacteriales cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GJF2@201174,4CZZ9@85004,COG0215@1,COG0215@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family NIBLCNGB_01908 326426.Bbr_0386 1.8e-133 481.9 Bifidobacteriales guaA1 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 2GNA6@201174,4CYR4@85004,COG0518@1,COG0518@2 NA|NA|NA F Peptidase C26 NIBLCNGB_01909 326426.Bbr_0387 0.0 1429.8 Bifidobacteriales yjjK ko:K15738 ko00000,ko02000 3.A.1.120.6 Bacteria 2GJ5M@201174,4CZCU@85004,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter NIBLCNGB_01910 326426.Bbr_0388 2.1e-73 281.6 Bifidobacteriales vapC ko:K07062,ko:K18828 ko00000,ko01000,ko02048,ko03016 Bacteria 2IS29@201174,4D1D3@85004,COG1487@1,COG1487@2 NA|NA|NA S Toxic component of a toxin-antitoxin (TA) module. An RNase NIBLCNGB_01911 326426.Bbr_0389 3.9e-44 183.7 Bifidobacteriales stbC ko:K21495 ko00000,ko02048 Bacteria 2GRCV@201174,4D1GB@85004,COG4691@1,COG4691@2 NA|NA|NA S Plasmid stability protein NIBLCNGB_01912 326426.Bbr_0390 4e-93 347.4 Bifidobacteriales ilvN GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ilvN,iJN678.ilvN Bacteria 2GJCH@201174,4CYXX@85004,COG0440@1,COG0440@2 NA|NA|NA E ACT domain NIBLCNGB_01913 326426.Bbr_0391 0.0 1320.4 Bifidobacteriales ilvB 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKU4@201174,4CYR0@85004,COG0028@1,COG0028@2 NA|NA|NA H Thiamine pyrophosphate enzyme, central domain NIBLCNGB_01914 326426.Bbr_0392 4.8e-134 483.8 Bifidobacteriales rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 2GKER@201174,4CZ98@85004,COG0571@1,COG0571@2 NA|NA|NA J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism NIBLCNGB_01915 326426.Bbr_0393 9.3e-21 105.5 Bifidobacteriales rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2GQP3@201174,4D18N@85004,COG0333@1,COG0333@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL32 family NIBLCNGB_01916 326426.Bbr_0394 7.6e-117 426.4 Bifidobacteriales yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K07040 ko00000 Bacteria 2GJTS@201174,4CZ0J@85004,COG1399@1,COG1399@2 NA|NA|NA S Uncharacterized ACR, COG1399 NIBLCNGB_01917 326426.Bbr_0395 4.1e-75 288.1 Bifidobacteriales Bacteria 2EKTZ@1,2HZD3@201174,33EHP@2,4CZV9@85004 NA|NA|NA NIBLCNGB_01918 326426.Bbr_0396 5.1e-87 327.0 Bifidobacteriales coaD 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN1S@201174,4CYR5@85004,COG0669@1,COG0669@2 NA|NA|NA H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate NIBLCNGB_01919 216816.GS08_01985 2.7e-48 197.6 Bifidobacteriales Bacteria 2CAFG@1,2I800@201174,32ZDZ@2,4D107@85004 NA|NA|NA S Protein of unknown function (DUF3039) NIBLCNGB_01920 326426.Bbr_0398 2.3e-195 688.0 Bifidobacteriales yghZ ko:K19265 ko00000,ko01000 Bacteria 2GMT5@201174,4CZ25@85004,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family NIBLCNGB_01921 326426.Bbr_0399 6.3e-78 296.6 Bifidobacteriales soxR Bacteria 2HZMI@201174,4D0Y1@85004,COG0789@1,COG0789@2 NA|NA|NA K MerR, DNA binding NIBLCNGB_01922 326426.Bbr_0400 4.5e-117 427.2 Bifidobacteriales Bacteria 2DR9G@1,2I45M@201174,33ASJ@2,4D2WG@85004 NA|NA|NA NIBLCNGB_01923 326426.Bbr_0401 4.7e-249 866.7 Bifidobacteriales pncB GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0030312,GO:0034355,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 Bacteria 2GJAT@201174,4CYUR@85004,COG1488@1,COG1488@2 NA|NA|NA F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP NIBLCNGB_01924 326426.Bbr_0402 4.1e-144 517.3 Bifidobacteriales rph GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56,3.6.1.66 ko:K00989,ko:K02428 ko00230,map00230 R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000,ko03016 Bacteria 2GJFI@201174,4CZBF@85004,COG0689@1,COG0689@2 NA|NA|NA J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates NIBLCNGB_01925 326426.Bbr_0403 4.8e-137 493.8 Bifidobacteriales rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 2GM2B@201174,4CZ3F@85004,COG0127@1,COG0127@2 NA|NA|NA F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions NIBLCNGB_01926 326426.Bbr_0404 3.6e-177 627.5 Bifidobacteriales ko:K07088 ko00000 Bacteria 2GN0R@201174,4CZ6C@85004,COG0679@1,COG0679@2 NA|NA|NA S Auxin Efflux Carrier NIBLCNGB_01929 326426.Bbr_0405 0.0 1146.7 Bifidobacteriales pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJG0@201174,4CYVV@85004,COG0166@1,COG0166@2 NA|NA|NA G Belongs to the GPI family NIBLCNGB_01930 326426.Bbr_0406 5.7e-261 906.4 Bifidobacteriales abcT3 ko:K02049 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 2GN33@201174,4D00C@85004,COG1116@1,COG1116@2,COG4754@1,COG4754@2 NA|NA|NA P ATPases associated with a variety of cellular activities NIBLCNGB_01931 326426.Bbr_0407 0.0 1138.6 Bifidobacteriales opuAB ko:K02050 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 2GNF7@201174,4CZJS@85004,COG4986@1,COG4986@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component NIBLCNGB_01932 326426.Bbr_0408 1.5e-59 235.3 Bifidobacteriales rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHRT@201174,4D0V2@85004,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site NIBLCNGB_01933 326426.Bbr_0409 3.8e-165 587.4 Bifidobacteriales lepB GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 2GIYN@201174,4CZEY@85004,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family NIBLCNGB_01934 326426.Bbr_0410 1e-159 569.3 Bifidobacteriales rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2GJFN@201174,4CZ1U@85004,COG0164@1,COG0164@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids NIBLCNGB_01935 326426.Bbr_0411 3.1e-209 734.2 Bifidobacteriales ko:K02529 ko00000,ko03000 Bacteria 2GK1X@201174,4CYR6@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor NIBLCNGB_01936 326426.Bbr_0413 0.0 1187.9 Bifidobacteriales fadD 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2GIXQ@201174,4CZZP@85004,COG1022@1,COG1022@2 NA|NA|NA I AMP-binding enzyme NIBLCNGB_01937 1437609.BCAL_0899 1.6e-77 295.8 Bifidobacteriales araE GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 ko:K02100 ko00000,ko02000 2.A.1.1.2 Bacteria 2GJF6@201174,4CZW6@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily NIBLCNGB_01939 326426.Bbr_0415 0.0 2439.8 Bifidobacteriales cydD GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 ko:K06147,ko:K06148,ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.129,3.A.1.21 Bacteria 2GITR@201174,4CYSB@85004,COG1132@1,COG1132@2,COG4988@1,COG4988@2 NA|NA|NA V ABC transporter transmembrane region NIBLCNGB_01940 216816.GS08_02150 5.2e-38 163.3 Bifidobacteriales ko:K05820,ko:K07552,ko:K08195 ko00000,ko02000 2.A.1.15,2.A.1.2,2.A.1.27 Bacteria 2GJF6@201174,4CZW6@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily NIBLCNGB_01941 326426.Bbr_0417 2.7e-260 904.0 Bifidobacteriales ko:K02027,ko:K10240 ko02010,map02010 M00206,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.23 Bacteria 2GJIP@201174,4CZU2@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_01942 326426.Bbr_0418 3.1e-100 371.3 Bifidobacteriales malC ko:K02025,ko:K10118,ko:K10241,ko:K15771 ko02010,map02010 M00196,M00206,M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.23,3.A.1.1.28 Bacteria 2GMTW@201174,4CZX2@85004,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component NIBLCNGB_01943 326426.Bbr_0420 0.0 1469.5 Bifidobacteriales bga1 3.2.1.23 ko:K12308 ko00052,map00052 R01105 RC00452 ko00000,ko00001,ko01000 Bacteria 2GMDT@201174,4CZ38@85004,COG1874@1,COG1874@2 NA|NA|NA G Psort location Cytoplasmic, score 8.87 NIBLCNGB_01944 326426.Bbr_0421 1.2e-191 675.6 Bifidobacteriales Bacteria 2GJ5Q@201174,4D040@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor NIBLCNGB_01945 326426.Bbr_0422 0.0 1598.9 Bifidobacteriales ganB 3.2.1.89 ko:K01224 ko00000,ko01000 Bacteria 2GP0I@201174,4CZYM@85004,COG3867@1,COG3867@2 NA|NA|NA G Glycosyl hydrolase family 53 NIBLCNGB_01947 326426.Bbr_0424 8e-165 586.3 Bifidobacteriales dkgA GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008106,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 iECH74115_1262.ECH74115_4323,iECSP_1301.ECSP_3988 Bacteria 2GJQ7@201174,4CYUN@85004,COG0656@1,COG0656@2 NA|NA|NA S Oxidoreductase, aldo keto reductase family protein NIBLCNGB_01948 326426.Bbr_0425 1e-139 502.7 Bifidobacteriales Bacteria 2GJ38@201174,4CZCY@85004,COG2356@1,COG2356@2 NA|NA|NA L Protein of unknown function (DUF1524) NIBLCNGB_01949 326426.Bbr_0427 1.1e-229 802.4 Bifidobacteriales mntH GO:0000041,GO:0003674,GO:0005215,GO:0005384,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015075,GO:0015077,GO:0015078,GO:0015086,GO:0015291,GO:0015292,GO:0015293,GO:0015318,GO:0015672,GO:0015684,GO:0015691,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0034755,GO:0042221,GO:0044425,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070574,GO:0070838,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071421,GO:0071577,GO:0071578,GO:0071944,GO:0072511,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098739,GO:0099587,GO:1902600 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 iSF_1195.SF2457,iYO844.BSU04360 Bacteria 2GJSM@201174,4CZZB@85004,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system NIBLCNGB_01950 326426.Bbr_0428 8.1e-280 969.1 Bifidobacteriales Bacteria 2GIZX@201174,4CZWX@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily NIBLCNGB_01951 326426.Bbr_0429 0.0 1167.5 Bifidobacteriales 2.1.1.107,2.1.1.294,2.7.1.181,2.7.11.1 ko:K02496,ko:K05802,ko:K08884,ko:K18827 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03194,R10657,R10658 RC00002,RC00003,RC00078,RC00871,RC03220 ko00000,ko00001,ko00002,ko01000,ko01001,ko01005,ko02000 1.A.23.1.1 Bacteria 2I2HI@201174,4CYVN@85004,COG2959@1,COG2959@2 NA|NA|NA H Protein of unknown function (DUF4012) NIBLCNGB_01952 326426.Bbr_0430 1e-309 1068.5 Bifidobacteriales rfbP 2.7.8.6 ko:K00996 ko00000,ko01000,ko01005 Bacteria 2GK0M@201174,4CZ4J@85004,COG1086@1,COG1086@2,COG2148@1,COG2148@2 NA|NA|NA M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase NIBLCNGB_01953 326426.Bbr_0431 8.2e-108 396.4 Bifidobacteriales 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 2GMPR@201174,4D0GD@85004,COG0394@1,COG0394@2 NA|NA|NA T Low molecular weight phosphatase family NIBLCNGB_01954 702459.BBPR_0084 1.6e-14 85.1 Bacteria Bacteria COG2826@1,COG2826@2 NA|NA|NA L transposase and inactivated derivatives, IS30 family NIBLCNGB_01955 702459.BBPR_0083 1.6e-45 189.5 Bifidobacteriales Bacteria 2GMZX@201174,4D0DN@85004,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives IS30 family NIBLCNGB_01956 518635.BIFANG_03640 8.7e-100 370.2 Bifidobacteriales cps1D Bacteria 2HFT7@201174,4CZBS@85004,COG1442@1,COG1442@2 NA|NA|NA M Domain of unknown function (DUF4422) NIBLCNGB_01958 77635.BISU_2468 1.1e-38 166.8 Bifidobacteriales ko:K19427 ko00000,ko01000 GT2 Bacteria 2I2EQ@201174,4D2B9@85004,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 NIBLCNGB_01959 484018.BACPLE_00051 3.6e-23 114.4 Bacteroidaceae Bacteria 2G0IU@200643,4AV8Z@815,4NNEE@976,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase, group 2 family protein NIBLCNGB_01962 1005704.HMPREF9968_2015 5.6e-13 80.1 Streptococcus oralis lsgF Bacteria 1V1CB@1239,1WQ9J@1303,4HHH7@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 NIBLCNGB_01963 1437609.BCAL_0101 4.5e-215 753.8 Bifidobacteriales Bacteria 2IBDV@201174,4CZS6@85004,COG4584@1,COG4584@2 NA|NA|NA L PFAM Integrase catalytic NIBLCNGB_01964 326426.Bbr_0152 9.8e-296 1021.9 Bifidobacteriales Bacteria 2IBDV@201174,4CZS6@85004,COG4584@1,COG4584@2 NA|NA|NA L PFAM Integrase catalytic NIBLCNGB_01965 326426.Bbr_0151 3.6e-148 530.8 Bifidobacteriales Bacteria 2H714@201174,4CZRM@85004,COG1484@1,COG1484@2 NA|NA|NA L IstB-like ATP binding protein NIBLCNGB_01966 1437609.BCAL_0101 4.2e-16 89.7 Bifidobacteriales Bacteria 2IBDV@201174,4CZS6@85004,COG4584@1,COG4584@2 NA|NA|NA L PFAM Integrase catalytic NIBLCNGB_01967 326426.Bbr_1401 5.3e-136 490.3 Bifidobacteriales Bacteria 2I90G@201174,4D05J@85004,COG1484@1,COG1484@2 NA|NA|NA L IstB-like ATP binding protein NIBLCNGB_01969 78345.BMERY_1170 3.5e-97 361.7 Bifidobacteriales Bacteria 2GPJB@201174,4D1BX@85004,COG3594@1,COG3594@2 NA|NA|NA G Acyltransferase family NIBLCNGB_01970 216816.GS08_04820 2.5e-80 304.7 Bifidobacteriales Bacteria 2H714@201174,4CZRM@85004,COG1484@1,COG1484@2 NA|NA|NA L IstB-like ATP binding protein NIBLCNGB_01971 518635.BIFANG_03165 1.2e-32 145.6 Bifidobacteriales Bacteria 2IRD7@201174,4D16D@85004,COG2963@1,COG2963@2 NA|NA|NA L Psort location Cytoplasmic, score 8.87 NIBLCNGB_01972 78346.BRUM_0084 8e-31 140.2 Bifidobacteriales Bacteria 2GKDY@201174,4CZQK@85004,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain NIBLCNGB_01973 547043.BIFPSEUDO_03313 3.8e-42 177.9 Bifidobacteriales cps1D Bacteria 2HFT7@201174,4CZBS@85004,COG1442@1,COG1442@2 NA|NA|NA M Domain of unknown function (DUF4422) NIBLCNGB_01974 518635.BIFANG_03644 1.1e-154 552.7 Bifidobacteriales Bacteria 2I2EQ@201174,4CZNW@85004,COG1216@1,COG1216@2 NA|NA|NA S Glycosyl transferase family 2 NIBLCNGB_01975 545696.HOLDEFILI_02051 2.4e-27 130.2 Firmicutes Bacteria 1VES5@1239,2CCRF@1,334T0@2 NA|NA|NA S Psort location CytoplasmicMembrane, score 9.99 NIBLCNGB_01976 518635.BIFANG_03646 4.2e-222 777.3 Bifidobacteriales Bacteria 2IA1K@201174,4D0KU@85004,COG2244@1,COG2244@2 NA|NA|NA S Psort location CytoplasmicMembrane, score 9.99 NIBLCNGB_01977 518635.BIFANG_03647 6.1e-175 620.2 Bifidobacteriales wbbI GO:0003674,GO:0003824,GO:0008194,GO:0008378,GO:0008921,GO:0016740,GO:0016757,GO:0016758,GO:0035250 iAF1260.b2034,iBWG_1329.BWG_1824,iECDH10B_1368.ECDH10B_2184,iECDH1ME8569_1439.ECDH1ME8569_1971,iECSF_1327.ECSF_1923,iEcDH1_1363.EcDH1_1623,iJO1366.b2034,iY75_1357.Y75_RS10645 Bacteria 2IEFR@201174,4CZQH@85004,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups NIBLCNGB_01978 518635.BIFANG_03648 1.3e-148 532.7 Bifidobacteriales 1.13.11.79 ko:K04719 ko00740,ko01100,map00740,map01100 R09083 RC00435,RC02413 ko00000,ko00001,ko01000 Bacteria 2IE9H@201174,4CZI3@85004,COG0778@1,COG0778@2 NA|NA|NA C Psort location Cytoplasmic, score 8.87 NIBLCNGB_01979 518635.BIFANG_03649 6.3e-132 477.2 Bifidobacteriales ko:K19427 ko00000,ko01000 GT2 Bacteria 2IPTK@201174,4D12W@85004,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 NIBLCNGB_01980 518635.BIFANG_03650 8.4e-181 639.8 Bifidobacteriales Bacteria 2I42G@201174,4D2WE@85004,COG1143@1,COG1143@2 NA|NA|NA C Polysaccharide pyruvyl transferase NIBLCNGB_01981 216816.GS08_07340 2.5e-26 124.4 Bifidobacteriales Bacteria 2H4CW@201174,4D25Y@85004,COG2826@1,COG2826@2 NA|NA|NA L Helix-turn-helix domain NIBLCNGB_01982 1437610.BREU_1897 2e-156 558.9 Bifidobacteriales Bacteria 2GKW1@201174,4D05P@85004,COG2801@1,COG2801@2,COG3415@1,COG3415@2 NA|NA|NA L PFAM Integrase catalytic NIBLCNGB_01984 1680.BADO_1364 6.8e-08 62.4 Bifidobacteriales ko:K06926 ko00000 Bacteria 2GMVX@201174,4CZWP@85004,COG1106@1,COG1106@2 NA|NA|NA S AAA domain, putative AbiEii toxin, Type IV TA system NIBLCNGB_01985 78346.BRUM_0079 5.2e-128 463.8 Bifidobacteriales insK GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 ko:K07497 ko00000 Bacteria 2H928@201174,4CZCP@85004,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain NIBLCNGB_01986 78346.BRUM_0813 1.2e-55 223.0 Bifidobacteriales Bacteria 2IF4K@201174,4D0JP@85004,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain NIBLCNGB_01987 78344.BIGA_1786 9e-14 84.0 Bifidobacteriales Bacteria 2GKW1@201174,4D05P@85004,COG2801@1,COG2801@2 NA|NA|NA L PFAM Integrase catalytic NIBLCNGB_01988 78344.BIGA_1603 1.9e-88 332.4 Actinobacteria Bacteria 2BTX1@1,2GTTM@201174,32P53@2 NA|NA|NA NIBLCNGB_01989 78344.BIGA_1604 1.5e-66 259.2 Bifidobacteriales Bacteria 2CM5B@1,2IRBQ@201174,32SDR@2,4D2GK@85004 NA|NA|NA NIBLCNGB_01990 1437610.BREU_1897 1.3e-26 125.2 Bifidobacteriales Bacteria 2GKW1@201174,4D05P@85004,COG2801@1,COG2801@2,COG3415@1,COG3415@2 NA|NA|NA L PFAM Integrase catalytic NIBLCNGB_01991 702459.BBPR_1823 1.8e-16 91.3 Bifidobacteriales Bacteria 2H4CW@201174,4D25Y@85004,COG2826@1,COG2826@2 NA|NA|NA L Helix-turn-helix domain NIBLCNGB_01992 326426.Bbr_0472 1.2e-247 862.1 Bifidobacteriales Bacteria 2C04M@1,2IBPG@201174,32Y5W@2,4D07E@85004 NA|NA|NA S Psort location CytoplasmicMembrane, score 9.99 NIBLCNGB_01994 216816.GS08_02275 6.4e-70 270.0 Bifidobacteriales Bacteria 28PY9@1,2INBV@201174,2ZCI0@2,4D13Q@85004 NA|NA|NA NIBLCNGB_01995 326426.Bbr_0474 2.6e-237 827.8 Bifidobacteriales wcoI ko:K16692 ko00000,ko01000,ko01001 Bacteria 2GJ1Y@201174,4CZKW@85004,COG0489@1,COG0489@2,COG3944@1,COG3944@2 NA|NA|NA DM Psort location CytoplasmicMembrane, score NIBLCNGB_01996 326426.Bbr_0475 2.9e-148 531.9 Bifidobacteriales Bacteria 2DDMI@1,2ICIR@201174,2ZIJN@2,4D00F@85004 NA|NA|NA NIBLCNGB_01997 326426.Bbr_0476 6.1e-169 600.1 Bifidobacteriales Bacteria 2I2GH@201174,4CYVC@85004,COG3583@1,COG3583@2 NA|NA|NA S G5 NIBLCNGB_01998 216816.GS08_02300 1.9e-59 235.0 Bifidobacteriales trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8,1.8.1.9 ko:K00384,ko:K03671,ko:K03672 ko00450,ko04621,ko05418,map00450,map04621,map05418 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000,ko03110 Bacteria 2IKP1@201174,4D11J@85004,COG0526@1,COG0526@2 NA|NA|NA O Belongs to the thioredoxin family NIBLCNGB_01999 216816.GS08_02305 4.2e-121 440.7 Bifidobacteriales Bacteria 2GJGZ@201174,4CYT1@85004,COG1051@1,COG1051@2 NA|NA|NA F Domain of unknown function (DUF4916) NIBLCNGB_02000 326426.Bbr_0479 1.4e-158 565.5 Bifidobacteriales mhpC Bacteria 2I2GI@201174,4CYXW@85004,COG2267@1,COG2267@2 NA|NA|NA I Alpha/beta hydrolase family NIBLCNGB_02001 326426.Bbr_0480 2e-212 745.0 Bifidobacteriales nudC GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0033554,GO:0034641,GO:0035529,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 1.3.7.1,3.6.1.22 ko:K03426,ko:K20449 ko00760,ko01100,ko01120,ko04146,map00760,map01100,map01120,map04146 R00103,R03004,R03164,R11104 RC00002,RC02422 ko00000,ko00001,ko01000 iAF1260.b3996,iB21_1397.B21_03826,iBWG_1329.BWG_3656,iEC55989_1330.EC55989_4481,iECBD_1354.ECBD_4036,iECB_1328.ECB_03873,iECDH10B_1368.ECDH10B_4185,iECDH1ME8569_1439.ECDH1ME8569_3856,iECD_1391.ECD_03873,iECIAI1_1343.ECIAI1_4211,iECO103_1326.ECO103_4745,iECO111_1330.ECO111_4813,iECO26_1355.ECO26_5105,iECSE_1348.ECSE_4284,iECW_1372.ECW_m4355,iEKO11_1354.EKO11_4325,iETEC_1333.ETEC_4256,iEcDH1_1363.EcDH1_3998,iEcE24377_1341.EcE24377A_4539,iEcHS_1320.EcHS_A4230,iEcolC_1368.EcolC_4029,iJO1366.b3996,iPC815.YPO3736,iSSON_1240.SSON_4169,iUMNK88_1353.UMNK88_4837,iWFL_1372.ECW_m4355,iY75_1357.Y75_RS17065,iYL1228.KPN_04378 Bacteria 2GJZY@201174,4CZE5@85004,COG2816@1,COG2816@2 NA|NA|NA L NADH pyrophosphatase zinc ribbon domain NIBLCNGB_02002 326426.Bbr_0481 5.9e-70 270.0 Bifidobacteriales gcvH ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 Bacteria 2IKN2@201174,4D0W7@85004,COG0509@1,COG0509@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein NIBLCNGB_02003 326426.Bbr_0482 2.1e-224 784.6 Bifidobacteriales Bacteria 2GKPS@201174,4CZ13@85004,COG4850@1,COG4850@2 NA|NA|NA S Uncharacterized conserved protein (DUF2183) NIBLCNGB_02004 326426.Bbr_0483 0.0 1886.7 Bifidobacteriales ptrB 3.4.21.83 ko:K01354 ko05142,ko05143,map05142,map05143 ko00000,ko00001,ko01000,ko01002 Bacteria 2GNA9@201174,4CZ2X@85004,COG1770@1,COG1770@2 NA|NA|NA E Peptidase, S9A B C family, catalytic domain protein NIBLCNGB_02005 326426.Bbr_0484 5.4e-192 676.8 Bifidobacteriales leuB 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GK44@201174,4CZ08@85004,COG0473@1,COG0473@2 NA|NA|NA CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate NIBLCNGB_02006 326426.Bbr_0485 4.3e-212 743.8 Bifidobacteriales lplA 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 Bacteria 2GJV5@201174,4CZYA@85004,COG0095@1,COG0095@2 NA|NA|NA H Biotin/lipoate A/B protein ligase family NIBLCNGB_02007 326426.Bbr_0486 2.1e-134 485.0 Bifidobacteriales glxR GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 Bacteria 2GMPN@201174,4CYYW@85004,COG0664@1,COG0664@2 NA|NA|NA K helix_turn_helix, cAMP Regulatory protein NIBLCNGB_02008 326426.Bbr_0487 0.0 1417.9 Bifidobacteriales pon1 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 2GK21@201174,4CZAZ@85004,COG0744@1,COG0744@2 NA|NA|NA M Transglycosylase NIBLCNGB_02009 326426.Bbr_0488 6.3e-230 803.1 Bifidobacteriales namA 1.6.99.1 ko:K00354 R00282 RC00001 ko00000,ko01000 Bacteria 2GK8E@201174,4CZ9Z@85004,COG1902@1,COG1902@2 NA|NA|NA C NADH:flavin oxidoreductase / NADH oxidase family NIBLCNGB_02010 326426.Bbr_0489 8.9e-228 795.8 Bifidobacteriales pyrD 1.3.1.14,1.3.5.2,1.3.98.1 ko:K00226,ko:K00254,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01868,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKC6@201174,4CYWW@85004,COG0167@1,COG0167@2 NA|NA|NA F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor NIBLCNGB_02011 326426.Bbr_0490 6.3e-123 446.8 Bifidobacteriales glpR ko:K02444 ko00000,ko03000 Bacteria 2H5X4@201174,4CZMT@85004,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain NIBLCNGB_02012 326426.Bbr_0491 1.9e-252 877.9 Bifidobacteriales galT 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2I2DM@201174,4CYXZ@85004,COG1085@1,COG1085@2 NA|NA|NA C Galactose-1-phosphate uridyl transferase, N-terminal domain NIBLCNGB_02013 326426.Bbr_0492 1.1e-231 808.9 Bifidobacteriales galK 2.7.1.6,2.7.7.12 ko:K00849,ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955,R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJXI@201174,4CZNV@85004,COG0153@1,COG0153@2 NA|NA|NA G Belongs to the GHMP kinase family. GalK subfamily NIBLCNGB_02014 326426.Bbr_0493 6.4e-44 183.0 Bifidobacteriales gcvR ko:K07166 ko00000 Bacteria 2IKS1@201174,4D11D@85004,COG3830@1,COG3830@2 NA|NA|NA T Belongs to the UPF0237 family NIBLCNGB_02015 326426.Bbr_0494 3.2e-253 880.6 Bifidobacteriales ko:K09157 ko00000 Bacteria 2HHMF@201174,4CZGB@85004,COG2848@1,COG2848@2 NA|NA|NA S UPF0210 protein NIBLCNGB_02016 158787.BSCA_0673 7.6e-115 419.9 Bifidobacteriales trmL GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 ko:K03216 ko00000,ko01000,ko03016 Bacteria 2IHN9@201174,4CZ0E@85004,COG0219@1,COG0219@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily NIBLCNGB_02017 326426.Bbr_0496 8.3e-187 659.4 Bifidobacteriales mutY 2.1.1.37,2.1.3.15,6.4.1.2 ko:K00558,ko:K01962,ko:K01963,ko:K03575 ko00061,ko00270,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03410,ko05206,map00061,map00270,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map03410,map05206 M00035,M00082,M00376 R00742,R04386,R04858 RC00003,RC00040,RC00253,RC00332,RC00367 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 2GJD9@201174,4CYRB@85004,COG1194@1,COG1194@2 NA|NA|NA L FES NIBLCNGB_02018 326426.Bbr_0497 3.9e-128 464.2 Bifidobacteriales Bacteria 2E5CN@1,2I2GJ@201174,3304R@2,4D0SD@85004 NA|NA|NA NIBLCNGB_02019 326426.Bbr_0498 0.0 2373.6 Bifidobacteriales rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2GJ81@201174,4CZ3W@85004,COG0085@1,COG0085@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates NIBLCNGB_02020 326426.Bbr_0499 0.0 2566.2 Bifidobacteriales rpoC GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2GKWF@201174,4CZ1D@85004,COG0086@1,COG0086@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates NIBLCNGB_02021 326426.Bbr_0500 0.0 1499.2 Bifidobacteriales Bacteria 2HQBB@201174,4CZ3X@85004,COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase-like superfamily NIBLCNGB_02022 326426.Bbr_0501 2.5e-239 834.3 Bifidobacteriales Bacteria 2GIWE@201174,4CZWT@85004,COG1721@1,COG1721@2 NA|NA|NA S Protein of unknown function DUF58 NIBLCNGB_02023 326426.Bbr_0502 0.0 4089.3 Bifidobacteriales ko:K03924,ko:K20276 ko02024,map02024 ko00000,ko00001,ko01000 Bacteria 2GMKC@201174,4CZFT@85004,COG0714@1,COG0714@2,COG4733@1,COG4733@2 NA|NA|NA S Fibronectin type 3 domain NIBLCNGB_02024 326426.Bbr_0504 1e-220 772.3 Bifidobacteriales Bacteria 2GIW5@201174,4CZ9N@85004,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase NIBLCNGB_02025 326426.Bbr_0505 0.0 2644.4 Bifidobacteriales uvrD 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJD0@201174,4CYQU@85004,COG0210@1,COG0210@2,COG2887@1,COG2887@2 NA|NA|NA L PD-(D/E)XK nuclease superfamily NIBLCNGB_02026 326426.Bbr_0506 0.0 2560.0 Bifidobacteriales uvrD2 3.6.4.12 ko:K03657,ko:K07465 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GM2E@201174,4CZ49@85004,COG0210@1,COG0210@2,COG2887@1,COG2887@2 NA|NA|NA L Belongs to the helicase family. UvrD subfamily NIBLCNGB_02027 326426.Bbr_0507 1.7e-235 821.6 Bifidobacteriales Bacteria 2I2GK@201174,4CZ0T@85004,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily NIBLCNGB_02028 326426.Bbr_0508 6.4e-134 483.4 Bifidobacteriales dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 iJN678.dapB,iYO844.BSU22490 Bacteria 2GM2T@201174,4CZJ5@85004,COG0289@1,COG0289@2 NA|NA|NA E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate NIBLCNGB_02029 326426.Bbr_0509 3.8e-162 577.4 Bifidobacteriales dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ34@201174,4CZ34@85004,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) NIBLCNGB_02030 216816.GS08_02580 0.0 1181.4 Bifidobacteriales rnj GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2GIW7@201174,4CZEJ@85004,COG0595@1,COG0595@2 NA|NA|NA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay NIBLCNGB_02031 326426.Bbr_0511 0.0 1751.9 Bifidobacteriales pepN 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJJ4@201174,4CZH4@85004,COG0308@1,COG0308@2 NA|NA|NA E Peptidase family M1 domain NIBLCNGB_02032 326426.Bbr_0512 2.6e-258 897.5 Bifidobacteriales glmM GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 R02060 RC00408 ko00000,ko00001,ko01000 iAF987.Gmet_1886,iLJ478.TM0184,iSB619.SA_RS11275,iSBO_1134.SBO_3206 Bacteria 2GN87@201174,4CYZX@85004,COG1109@1,COG1109@2 NA|NA|NA G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate NIBLCNGB_02033 326426.Bbr_0513 7.5e-123 446.4 Bifidobacteriales def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 ko00000,ko01000 Bacteria 2GNZ9@201174,4CZ7M@85004,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions NIBLCNGB_02034 326426.Bbr_0514 6.5e-268 929.5 Bifidobacteriales recE GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005515,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008309,GO:0008409,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0035312,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051908,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 2.7.7.7,3.6.4.12 ko:K02335,ko:K02342,ko:K03654,ko:K03722,ko:K10906 ko00230,ko00240,ko01100,ko03018,ko03030,ko03410,ko03420,ko03430,ko03440,map00230,map00240,map01100,map03018,map03030,map03410,map03420,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IC59@201174,4CZY1@85004,COG0847@1,COG0847@2 NA|NA|NA L Psort location Cytoplasmic, score NIBLCNGB_02035 326426.Bbr_0515 1.6e-205 721.8 Bifidobacteriales prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 2GJ0F@201174,4CZJX@85004,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA NIBLCNGB_02036 326426.Bbr_0516 1.3e-205 722.2 Bifidobacteriales ftsE GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 ko:K09811,ko:K09812 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 2GJE1@201174,4CYYQ@85004,COG2884@1,COG2884@2 NA|NA|NA D Cell division ATP-binding protein FtsE NIBLCNGB_02037 326426.Bbr_0517 9.8e-161 572.8 Bifidobacteriales ftsX GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531 ko:K09811,ko:K09812 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 2GJMA@201174,4CZSQ@85004,COG2177@1,COG2177@2 NA|NA|NA D Part of the ABC transporter FtsEX involved in cellular division NIBLCNGB_02038 326426.Bbr_0518 9e-147 526.9 Bifidobacteriales usp 3.5.1.28 ko:K21471,ko:K22409 ko00000,ko01000,ko01002,ko01011 CBM50 Bacteria 2GZG8@201174,4CYQJ@85004,COG3942@1,COG3942@2 NA|NA|NA D CHAP domain protein NIBLCNGB_02039 326426.Bbr_0519 1.4e-78 298.9 Bifidobacteriales smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 ko:K03664 ko00000 Bacteria 2GJX1@201174,4CZG4@85004,COG0691@1,COG0691@2 NA|NA|NA J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA NIBLCNGB_02040 326426.Bbr_0520 5.6e-143 513.8 Bifidobacteriales pknD ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2GJQW@201174,4CZ6H@85004,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter, substrate-binding protein, family 3 NIBLCNGB_02041 326426.Bbr_0521 4.9e-168 597.0 Bifidobacteriales pknD ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2GJQW@201174,4CZ6H@85004,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter, substrate-binding protein, family 3 NIBLCNGB_02042 326426.Bbr_0522 1.6e-153 548.9 Bifidobacteriales yecS ko:K02029,ko:K10009 ko02010,map02010 M00234,M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.10,3.A.1.3.14 Bacteria 2GJJ9@201174,4CYSN@85004,COG0765@1,COG0765@2 NA|NA|NA E Binding-protein-dependent transport system inner membrane component NIBLCNGB_02043 326426.Bbr_0523 1.4e-150 538.9 Bifidobacteriales tcyC 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 2GIZW@201174,4CZSB@85004,COG1126@1,COG1126@2 NA|NA|NA E ATPases associated with a variety of cellular activities NIBLCNGB_02044 326426.Bbr_0524 0.0 1251.5 Bifidobacteriales glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 iNJ661.Rv3436c,iSB619.SA_RS11245,iYO844.BSU01780 Bacteria 2GKH0@201174,4CZ1G@85004,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source NIBLCNGB_02045 326426.Bbr_0525 5.3e-158 563.5 Bifidobacteriales rluA 5.4.99.28,5.4.99.29 ko:K06177 ko00000,ko01000,ko03009,ko03016 Bacteria 2GJ2Z@201174,4CZB2@85004,COG0564@1,COG0564@2 NA|NA|NA J RNA pseudouridylate synthase NIBLCNGB_02046 326426.Bbr_0526 1.5e-186 658.7 Bifidobacteriales ko:K02529 ko00000,ko03000 Bacteria 2GK1X@201174,4CZWK@85004,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding protein domain NIBLCNGB_02047 326426.Bbr_0527 1.4e-167 595.5 Bifidobacteriales malC ko:K02025,ko:K10118,ko:K10241,ko:K15771 ko02010,map02010 M00196,M00206,M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.23,3.A.1.1.28 Bacteria 2GMTW@201174,4CZX2@85004,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component NIBLCNGB_02048 326426.Bbr_0528 6.8e-168 596.7 Bifidobacteriales ko:K02026 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GJPZ@201174,4CYV5@85004,COG0395@1,COG0395@2 NA|NA|NA G ABC transporter permease NIBLCNGB_02049 326426.Bbr_0529 0.0 1434.9 Bifidobacteriales lacZ5 3.2.1.23 ko:K12308 ko00052,map00052 R01105 RC00452 ko00000,ko00001,ko01000 Bacteria 2GMDT@201174,4CZ38@85004,COG1874@1,COG1874@2 NA|NA|NA G Psort location Cytoplasmic, score 8.87 NIBLCNGB_02050 326426.Bbr_0530 2.5e-258 897.5 Bifidobacteriales ko:K02027,ko:K10240 ko02010,map02010 M00206,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.23 Bacteria 2GJIP@201174,4CYRE@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_02051 326426.Bbr_0531 1.5e-277 961.4 Bifidobacteriales ko:K02027,ko:K10240 ko02010,map02010 M00206,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.23 Bacteria 2GJIP@201174,4CYRE@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_02052 326426.Bbr_0532 5.9e-143 513.5 Bifidobacteriales coaX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1986 Bacteria 2GMRQ@201174,4CZQS@85004,COG1521@1,COG1521@2 NA|NA|NA H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis NIBLCNGB_02053 326426.Bbr_0533 8e-291 1005.7 Bifidobacteriales ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GJ4B@201174,4CYWF@85004,COG0747@1,COG0747@2 NA|NA|NA E ABC transporter, substrate-binding protein, family 5 NIBLCNGB_02054 326426.Bbr_0534 6.3e-166 590.1 Bifidobacteriales ko:K02033 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GK0Z@201174,4CYST@85004,COG0601@1,COG0601@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component NIBLCNGB_02055 326426.Bbr_0535 1e-147 529.6 Bifidobacteriales ko:K02031,ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2GNQ5@201174,4CZ84@85004,COG1173@1,COG1173@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component NIBLCNGB_02056 326426.Bbr_0536 1.9e-136 491.9 Bifidobacteriales oppD ko:K02031 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GIXV@201174,4CZ3U@85004,COG0444@1,COG0444@2 NA|NA|NA EP oligopeptide transport protein of the ABC superfamily, ATP-binding component NIBLCNGB_02057 326426.Bbr_0537 2e-138 498.4 Bifidobacteriales sapF ko:K02032,ko:K19230 ko01503,ko02010,ko02024,map01503,map02010,map02024 M00239,M00739 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.5 Bacteria 2GP46@201174,4CYXD@85004,COG4608@1,COG4608@2 NA|NA|NA E ATPases associated with a variety of cellular activities NIBLCNGB_02058 326426.Bbr_0538 4.8e-193 680.2 Bifidobacteriales cbs GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00035,M00338 R00891,R00897,R01290,R03601,R04859,R04942 RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIXE@201174,4CYQ4@85004,COG0031@1,COG0031@2 NA|NA|NA E Pyridoxal-phosphate dependent enzyme NIBLCNGB_02059 326426.Bbr_0539 2.4e-220 771.2 Bifidobacteriales metB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.8 ko:K01739,ko:K01758,ko:K01760 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 iNJ661.Rv1079 Bacteria 2GJ5S@201174,4CYY2@85004,COG0626@1,COG0626@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme NIBLCNGB_02060 326426.Bbr_0540 0.0 1266.1 Bifidobacteriales recQ 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJSS@201174,4CZ0I@85004,COG0514@1,COG0514@2 NA|NA|NA L ATP-dependent DNA helicase RecQ NIBLCNGB_02061 326426.Bbr_0541 2.7e-93 347.8 Bifidobacteriales luxS GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300 Bacteria 2GJVF@201174,4CYZ4@85004,COG1854@1,COG1854@2 NA|NA|NA H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) NIBLCNGB_02062 326426.Bbr_0542 1.7e-104 385.2 Bifidobacteriales cysE 2.3.1.178 ko:K06718 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06978 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 2HBE2@201174,4CZTR@85004,COG1670@1,COG1670@2 NA|NA|NA J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins NIBLCNGB_02063 326426.Bbr_0543 7.7e-269 932.6 Bifidobacteriales yhdG ko:K03294 ko00000 2.A.3.2 Bacteria 2GJ75@201174,4CYZA@85004,COG0531@1,COG0531@2 NA|NA|NA E aromatic amino acid transport protein AroP K03293 NIBLCNGB_02064 326426.Bbr_0544 1e-262 912.1 Bifidobacteriales alr GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006082,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008784,GO:0009058,GO:0009059,GO:0009078,GO:0009079,GO:0009252,GO:0009273,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0019842,GO:0030170,GO:0030203,GO:0030632,GO:0034645,GO:0036094,GO:0036361,GO:0040007,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047661,GO:0048037,GO:0050662,GO:0070279,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011 iEC55989_1330.EC55989_1285,iECIAI39_1322.ECIAI39_1880,iECO103_1326.ECO103_1292,iECO26_1355.ECO26_1703,iECSE_1348.ECSE_1238,iECUMN_1333.ECUMN_1479,iECW_1372.ECW_m1275,iEKO11_1354.EKO11_2666,iEcE24377_1341.EcE24377A_1335,iPC815.YPO0321,iSBO_1134.SBO_4064,iSbBS512_1146.SbBS512_E4542,iWFL_1372.ECW_m1275,iYL1228.KPN_02308,iYL1228.KPN_04440 Bacteria 2GM2Y@201174,4CZ2Q@85004,COG0787@1,COG0787@2 NA|NA|NA M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids NIBLCNGB_02065 326426.Bbr_0545 3.1e-245 854.0 Bifidobacteriales dgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 ko:K01129 ko00230,map00230 R01856 RC00017 ko00000,ko00001,ko01000 Bacteria 2GJ8F@201174,4CYYP@85004,COG0232@1,COG0232@2 NA|NA|NA F Phosphohydrolase-associated domain NIBLCNGB_02066 326426.Bbr_0546 0.0 1392.5 Bifidobacteriales dnaG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2GJFX@201174,4CYZG@85004,COG0358@1,COG0358@2 NA|NA|NA L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication NIBLCNGB_02067 326426.Bbr_0547 1.8e-69 268.5 Bifidobacteriales Bacteria 2INKB@201174,4D149@85004,COG1848@1,COG1848@2 NA|NA|NA S PIN domain NIBLCNGB_02068 326426.Bbr_0548 5.1e-34 149.8 Bifidobacteriales Bacteria 2EH4D@1,2GZXK@201174,33AWC@2,4D1PF@85004 NA|NA|NA NIBLCNGB_02069 326426.Bbr_0549 3.1e-156 557.8 Bifidobacteriales pdxS GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 ko:K06215 ko00750,map00750 R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 Bacteria 2GK1T@201174,4CZ5P@85004,COG0214@1,COG0214@2 NA|NA|NA H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively NIBLCNGB_02070 326426.Bbr_0550 1.1e-115 422.5 Bifidobacteriales pdxT GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 ko:K08681 ko00750,map00750 R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 iHN637.CLJU_RS19495 Bacteria 2GNYG@201174,4CYUS@85004,COG0311@1,COG0311@2 NA|NA|NA H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS NIBLCNGB_02071 326426.Bbr_0551 1.4e-292 1011.5 Bifidobacteriales ko:K03710,ko:K18907 M00700,M00702 ko00000,ko00002,ko01504,ko03000 Bacteria 2GITW@201174,4CZGJ@85004,COG1167@1,COG1167@2 NA|NA|NA EK Alanine-glyoxylate amino-transferase NIBLCNGB_02072 326426.Bbr_0552 1.1e-209 735.7 Bifidobacteriales ybiR GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2GP6U@201174,4CZ37@85004,COG1055@1,COG1055@2 NA|NA|NA P Citrate transporter NIBLCNGB_02073 326426.Bbr_0553 3.3e-30 137.1 Bifidobacteriales Bacteria 2B4W6@1,2GZB9@201174,31XNV@2,4D1T7@85004 NA|NA|NA NIBLCNGB_02074 1437608.BBIA_0865 7e-43 180.3 Bifidobacteriales Bacteria 2GP9Z@201174,4CZ95@85004,COG3534@1,COG3534@2 NA|NA|NA G Alpha-L-arabinofuranosidase C-terminal domain NIBLCNGB_02075 326426.Bbr_0555 1.5e-158 565.5 Bifidobacteriales Bacteria 2HY2W@201174,4D050@85004,COG1737@1,COG1737@2 NA|NA|NA K Helix-turn-helix domain, rpiR family NIBLCNGB_02078 326426.Bbr_0557 3.6e-257 893.6 Bifidobacteriales ko:K02027,ko:K10240 ko02010,map02010 M00206,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.23 Bacteria 2GJIP@201174,4CYRE@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_02079 326426.Bbr_0558 9.9e-225 785.8 Bifidobacteriales Bacteria 2GJDS@201174,4CZR6@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor NIBLCNGB_02080 326426.Bbr_0559 0.0 1265.0 Bifidobacteriales 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13 Bacteria 2GKS4@201174,4CZT7@85004,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain protein NIBLCNGB_02081 216816.GS08_10200 4.5e-13 80.1 Bifidobacteriales ko:K07483 ko00000 Bacteria 2IRD7@201174,4D16D@85004,COG2963@1,COG2963@2 NA|NA|NA L Psort location Cytoplasmic, score 8.87 NIBLCNGB_02082 326426.Bbr_0560 2.2e-311 1073.9 Bifidobacteriales ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2GIUH@201174,4CZFK@85004,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substrate-binding protein, family 5 NIBLCNGB_02083 326426.Bbr_0561 1.6e-85 322.0 Bacteria msrA 1.8.4.11,1.8.4.12 ko:K12267 ko00000,ko01000 Bacteria COG0225@1,COG0225@2 NA|NA|NA O peptide-methionine (S)-S-oxide reductase activity NIBLCNGB_02084 326426.Bbr_0562 6.2e-135 486.9 Bifidobacteriales ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJN6@201174,4D2SJ@85004,COG1136@1,COG1136@2 NA|NA|NA V ATPases associated with a variety of cellular activities NIBLCNGB_02085 326426.Bbr_0563 9.1e-181 639.8 Bifidobacteriales Bacteria 2GP6I@201174,4D013@85004,COG1361@1,COG1361@2 NA|NA|NA M Conserved repeat domain NIBLCNGB_02086 326426.Bbr_0564 7.2e-286 989.2 Bifidobacteriales macB_8 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GIRW@201174,4CZMQ@85004,COG0577@1,COG0577@2,COG4591@1,COG4591@2 NA|NA|NA V MacB-like periplasmic core domain NIBLCNGB_02087 326426.Bbr_0565 0.0 1353.6 Bifidobacteriales dxs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMFA@201174,4CZ2M@85004,COG1154@1,COG1154@2 NA|NA|NA H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) NIBLCNGB_02088 326426.Bbr_0566 4.8e-182 643.7 Bifidobacteriales adh3 Bacteria 2GMHR@201174,4D00X@85004,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase NIBLCNGB_02089 326426.Bbr_0567 7.3e-86 323.2 Bifidobacteriales purE GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551 Bacteria 2IFFD@201174,4CYQZ@85004,COG0041@1,COG0041@2 NA|NA|NA F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) NIBLCNGB_02090 216816.GS08_02915 4.2e-225 786.9 Bifidobacteriales purK 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJCU@201174,4CYWP@85004,COG0026@1,COG0026@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) NIBLCNGB_02091 326426.Bbr_0569 1.2e-68 265.8 Bifidobacteriales zur GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02076,ko:K03711,ko:K09823 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria 2IKS3@201174,4D0XG@85004,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family NIBLCNGB_02092 158787.BSCA_2103 5.7e-84 317.4 Bifidobacteriales ylbB ko:K02004,ko:K06994 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2I2FK@201174,4CZJR@85004,COG0577@1,COG0577@2,COG1511@1,COG1511@2 NA|NA|NA V FtsX-like permease family NIBLCNGB_02093 1437608.BBIA_0567 2.9e-27 128.3 Bifidobacteriales ylbB ko:K02004,ko:K06994 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2I2FK@201174,4CZJR@85004,COG0577@1,COG0577@2,COG1511@1,COG1511@2 NA|NA|NA V FtsX-like permease family NIBLCNGB_02094 1437608.BBIA_0566 4e-70 271.2 Bifidobacteriales XK27_06785 ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJQV@201174,4CYT2@85004,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter NIBLCNGB_02095 326426.Bbr_0572 2.7e-63 247.7 Bifidobacteriales Bacteria 2AUUP@1,2IKU9@201174,31KHW@2,4D15K@85004 NA|NA|NA NIBLCNGB_02096 326426.Bbr_0573 8.7e-27 125.9 Bifidobacteriales zur GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02076,ko:K03711,ko:K09823 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria 2IKS3@201174,4D15A@85004,COG0735@1,COG0735@2 NA|NA|NA P Ferric uptake regulator family NIBLCNGB_02097 326426.Bbr_0574 7.8e-140 503.1 Bifidobacteriales ko:K08986 ko00000 Bacteria 2I8JS@201174,4CZZQ@85004,COG3689@1,COG3689@2 NA|NA|NA S TIGRFAM TIGR03943 family protein NIBLCNGB_02098 326426.Bbr_0575 1.4e-180 639.0 Bifidobacteriales ycgR ko:K07089 ko00000 Bacteria 2GJQ0@201174,4D057@85004,COG0701@1,COG0701@2 NA|NA|NA S Predicted permease NIBLCNGB_02100 326426.Bbr_0579 6.1e-155 553.5 Bifidobacteriales ko:K02077 M00244 ko00000,ko00002,ko02000 3.A.1.15 Bacteria 2GM1K@201174,4CZ99@85004,COG0803@1,COG0803@2 NA|NA|NA P Zinc-uptake complex component A periplasmic NIBLCNGB_02101 326426.Bbr_0580 0.0 1330.9 Bifidobacteriales XK27_08315 Bacteria 2HVID@201174,4CZ6J@85004,COG1368@1,COG1368@2 NA|NA|NA M Psort location CytoplasmicMembrane, score 9.26 NIBLCNGB_02102 326426.Bbr_0581 1e-295 1021.9 Bifidobacteriales aldH 1.2.1.3,1.2.1.5 ko:K00128,ko:K00129 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00980,ko00981,ko00982,ko01100,ko01110,ko01120,ko01130,ko05204,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00903,map00980,map00981,map00982,map01100,map01110,map01120,map01130,map05204 M00135 R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02536,R02537,R02549,R02678,R02695,R02697,R02940,R02957,R03283,R03300,R03302,R03869,R04065,R04506,R04882,R04883,R04888,R04889,R04891,R04892,R04903,R04996,R05050,R05237,R05238,R05286,R06366,R07104,R08146,R08282,R08283,R08307 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500,RC01735 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIWZ@201174,4CZQF@85004,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family NIBLCNGB_02103 326426.Bbr_0582 5.3e-242 843.2 Bifidobacteriales purD 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS05245,iYO844.BSU06530 Bacteria 2I2F5@201174,4CZ3I@85004,COG0151@1,COG0151@2 NA|NA|NA F Belongs to the GARS family NIBLCNGB_02104 326426.Bbr_0583 4.1e-184 650.6 Bifidobacteriales purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 ko:K01933,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1844,iECSF_1327.ECSF_2340 Bacteria 2GJNY@201174,4CZ3K@85004,COG0150@1,COG0150@2 NA|NA|NA F Phosphoribosylformylglycinamidine cyclo-ligase NIBLCNGB_02105 326426.Bbr_0584 2.7e-293 1013.8 Bifidobacteriales purF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 iSB619.SA_RS05225 Bacteria 2GK6I@201174,4CZ89@85004,COG0034@1,COG0034@2 NA|NA|NA F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine NIBLCNGB_02106 326426.Bbr_0585 1.6e-299 1034.6 Bifidobacteriales umuC 2.7.7.7 ko:K02346,ko:K03502,ko:K14161 ko00000,ko01000,ko03400 Bacteria 2GQX7@201174,4CZ0D@85004,COG0389@1,COG0389@2 NA|NA|NA L DNA-damage repair protein (DNA polymerase IV) K00961 NIBLCNGB_02107 326426.Bbr_0586 1.3e-31 141.7 Bifidobacteriales Bacteria 2DTWH@1,2GUGG@201174,33MZC@2,4D1FM@85004 NA|NA|NA NIBLCNGB_02108 216816.GS08_02990 1.5e-13 81.3 Bifidobacteriales GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008076,GO:0008150,GO:0008152,GO:0009117,GO:0009898,GO:0009987,GO:0010959,GO:0012505,GO:0012506,GO:0015459,GO:0016020,GO:0016021,GO:0016192,GO:0016247,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019637,GO:0019897,GO:0019898,GO:0030141,GO:0030424,GO:0030659,GO:0030667,GO:0031090,GO:0031224,GO:0031226,GO:0031234,GO:0031410,GO:0031982,GO:0032879,GO:0032880,GO:0032940,GO:0032991,GO:0033267,GO:0034641,GO:0034702,GO:0034703,GO:0034705,GO:0034762,GO:0034765,GO:0035579,GO:0036230,GO:0042119,GO:0042581,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043266,GO:0043269,GO:0043299,GO:0043312,GO:0044224,GO:0044237,GO:0044238,GO:0044281,GO:0044304,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046496,GO:0046903,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051179,GO:0051186,GO:0051234,GO:0055086,GO:0055114,GO:0060341,GO:0065007,GO:0065009,GO:0070820,GO:0070821,GO:0070995,GO:0071704,GO:0071944,GO:0072524,GO:0097458,GO:0097708,GO:0098552,GO:0098562,GO:0098588,GO:0098772,GO:0098796,GO:0098797,GO:0098805,GO:0099106,GO:0099503,GO:0120025,GO:0120038,GO:1901360,GO:1901379,GO:1901564,GO:1902495,GO:1903827,GO:1904062,GO:1990031,GO:1990351,GO:2000008 Bacteria 2GMT5@201174,4CZ8K@85004,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family NIBLCNGB_02109 326426.Bbr_0588 1.1e-102 379.4 Bifidobacteriales mug 3.2.2.28 ko:K03575,ko:K03649 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2IGMS@201174,4D0QQ@85004,COG3663@1,COG3663@2 NA|NA|NA L Uracil DNA glycosylase superfamily NIBLCNGB_02110 398513.BBNG_01260 2.4e-08 64.7 Bifidobacteriales Bacteria 2ADW4@1,2IEGF@201174,313N4@2,4CZI1@85004 NA|NA|NA S Protein of unknown function (DUF4230) NIBLCNGB_02113 216816.GS08_03025 1.5e-29 134.8 Bifidobacteriales Bacteria 2ADW4@1,2IEGF@201174,313N4@2,4CZI1@85004 NA|NA|NA S Protein of unknown function (DUF4230) NIBLCNGB_02114 216816.GS08_03030 1.9e-144 518.5 Bifidobacteriales Bacteria 2EDPB@1,2IE1I@201174,337J0@2,4D01N@85004 NA|NA|NA NIBLCNGB_02115 326426.Bbr_0594 8.4e-114 416.4 Bifidobacteriales Bacteria 2GIS8@201174,4D0BP@85004,COG1020@1,COG1020@2 NA|NA|NA Q D-alanine [D-alanyl carrier protein] ligase activity NIBLCNGB_02116 326426.Bbr_0595 2.3e-254 884.4 Bifidobacteriales Bacteria 2H4CN@201174,4D0AP@85004,COG1020@1,COG1020@2 NA|NA|NA Q D-alanine [D-alanyl carrier protein] ligase activity NIBLCNGB_02117 216816.GS08_03045 8.2e-222 776.2 Bifidobacteriales ko:K01066 ko00000,ko01000 Bacteria 2GKX2@201174,4CYYK@85004,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold NIBLCNGB_02118 326426.Bbr_0597 0.0 2375.9 Bifidobacteriales purL 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKG6@201174,4CZ7C@85004,COG0046@1,COG0046@2,COG0047@1,COG0047@2 NA|NA|NA F CobB/CobQ-like glutamine amidotransferase domain NIBLCNGB_02119 326426.Bbr_0598 3.3e-138 497.7 Bifidobacteriales purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016881,GO:0044424,GO:0044444,GO:0044464 4.1.1.21,4.3.2.2,6.3.2.6 ko:K01587,ko:K01756,ko:K01923 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04209,R04559,R04591 RC00064,RC00162,RC00379,RC00444,RC00445,RC00590 ko00000,ko00001,ko00002,ko01000 iAF1260.b2476,iB21_1397.B21_02330,iBWG_1329.BWG_2240,iE2348C_1286.E2348C_2713,iEC042_1314.EC042_2677,iEC55989_1330.EC55989_2759,iECABU_c1320.ECABU_c27880,iECBD_1354.ECBD_1213,iECB_1328.ECB_02368,iECDH10B_1368.ECDH10B_2642,iECDH1ME8569_1439.ECDH1ME8569_2402,iECDH1ME8569_1439.EcDH1_1193,iECD_1391.ECD_02368,iECED1_1282.ECED1_2911,iECH74115_1262.ECH74115_3698,iECIAI1_1343.ECIAI1_2527,iECNA114_1301.ECNA114_2561,iECO103_1326.ECO103_2988,iECO111_1330.ECO111_3199,iECO26_1355.ECO26_3522,iECOK1_1307.ECOK1_2784,iECP_1309.ECP_2490,iECS88_1305.ECS88_2658,iECSE_1348.ECSE_2760,iECSF_1327.ECSF_2329,iECSP_1301.ECSP_3415,iECUMN_1333.ECUMN_2789,iECW_1372.ECW_m2698,iECs_1301.ECs3338,iEKO11_1354.EKO11_1259,iETEC_1333.ETEC_2581,iEcDH1_1363.EcDH1_1193,iEcE24377_1341.EcE24377A_2757,iEcHS_1320.EcHS_A2607,iEcSMS35_1347.EcSMS35_2623,iEcolC_1368.EcolC_1200,iG2583_1286.G2583_2999,iJN746.PP_1240,iJO1366.b2476,iJR904.b2476,iLF82_1304.LF82_1775,iNRG857_1313.NRG857_12360,iSFV_1184.SFV_2521,iSF_1195.SF2519,iSFxv_1172.SFxv_2773,iS_1188.S2669,iSbBS512_1146.SbBS512_E2848,iUMNK88_1353.UMNK88_3071,iWFL_1372.ECW_m2698,iY75_1357.Y75_RS12925,iYL1228.KPN_02810,iZ_1308.Z3735 Bacteria 2GK3H@201174,4CZGQ@85004,COG0152@1,COG0152@2 NA|NA|NA F Belongs to the SAICAR synthetase family NIBLCNGB_02120 326426.Bbr_0599 5.3e-221 773.5 Bifidobacteriales purT GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008776,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016741,GO:0016742,GO:0016772,GO:0016774,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0389,iSDY_1059.SDY_1135 Bacteria 2GMCS@201174,4CZXH@85004,COG0027@1,COG0027@2 NA|NA|NA F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate NIBLCNGB_02121 326426.Bbr_0600 2.5e-228 797.7 Bifidobacteriales mtnE GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016740,GO:0016769,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249 2.6.1.83 ko:K08969,ko:K10206,ko:K19549 ko00270,ko00300,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map01100,map01110,map01130,map01230 M00034,M00527,M00787 R07396,R07613,R11068 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GJ7R@201174,4CZCF@85004,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase class I and II NIBLCNGB_02122 326426.Bbr_0601 8.1e-221 772.7 Bifidobacteriales Bacteria 2HEH6@201174,4CZSN@85004,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase 4-like domain NIBLCNGB_02123 326426.Bbr_0602 1.5e-194 685.3 Bifidobacteriales ltaE 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 Bacteria 2GJ0V@201174,4CZ7G@85004,COG2008@1,COG2008@2 NA|NA|NA E Beta-eliminating lyase NIBLCNGB_02125 326426.Bbr_0603 6.6e-111 406.8 Bifidobacteriales yocS ko:K03453 ko00000 2.A.28 Bacteria 2GMAM@201174,4CZ1K@85004,COG0385@1,COG0385@2 NA|NA|NA S SBF-like CPA transporter family (DUF4137) NIBLCNGB_02126 904144.AEJD01000003_gene1022 9.3e-62 242.7 Bifidobacteriales rpsL GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02950 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHUF@201174,4D0PK@85004,COG0048@1,COG0048@2 NA|NA|NA J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit NIBLCNGB_02127 1437610.BREU_2069 3.3e-80 304.3 Bifidobacteriales rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02992 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GMVW@201174,4CZQJ@85004,COG0049@1,COG0049@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA NIBLCNGB_02128 326426.Bbr_0606 0.0 1409.4 Bifidobacteriales fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02355 ko00000,ko03012,ko03029 Bacteria 2GKB3@201174,4CYTB@85004,COG0480@1,COG0480@2 NA|NA|NA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome NIBLCNGB_02129 326426.Bbr_0607 6.2e-232 809.7 Bifidobacteriales tuf GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 ko:K02358 ko00000,ko03012,ko03029,ko04147 Bacteria 2GK4T@201174,4CYY7@85004,COG0050@1,COG0050@2 NA|NA|NA J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis NIBLCNGB_02130 326426.Bbr_0608 2.1e-126 458.4 Bifidobacteriales tmp1 Bacteria 28XY7@1,2GN31@201174,2ZJU4@2,4CZQG@85004 NA|NA|NA S Domain of unknown function (DUF4391) NIBLCNGB_02131 326426.Bbr_0609 7.8e-146 523.1 Bifidobacteriales rlrG ko:K21900 ko00000,ko03000 Bacteria 2HZCS@201174,4CZT1@85004,COG0583@1,COG0583@2 NA|NA|NA K Bacterial regulatory helix-turn-helix protein, lysR family NIBLCNGB_02132 326426.Bbr_0610 7.8e-186 656.4 Bifidobacteriales MA20_14895 Bacteria 2GS6E@201174,4CZWB@85004,COG2855@1,COG2855@2 NA|NA|NA S Conserved hypothetical protein 698 NIBLCNGB_02133 326426.Bbr_0612 2.5e-59 234.6 Bifidobacteriales crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 2IC26@201174,4D14T@85004,COG0239@1,COG0239@2 NA|NA|NA U Important for reducing fluoride concentration in the cell, thus reducing its toxicity NIBLCNGB_02134 326426.Bbr_0613 2.4e-87 328.2 Bifidobacteriales ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 2IJGQ@201174,4D11I@85004,COG0239@1,COG0239@2 NA|NA|NA D Important for reducing fluoride concentration in the cell, thus reducing its toxicity NIBLCNGB_02135 326426.Bbr_0614 1.1e-75 289.7 Bifidobacteriales Bacteria 2HZK3@201174,4D0RM@85004,COG0789@1,COG0789@2 NA|NA|NA K MerR family regulatory protein NIBLCNGB_02136 326426.Bbr_0615 4.9e-193 680.2 Bifidobacteriales 1.1.1.1,1.1.1.14 ko:K00001,ko:K00008 ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 M00014 R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko00002,ko01000 Bacteria 2GISW@201174,4CZJY@85004,COG1063@1,COG1063@2 NA|NA|NA C Zinc-binding dehydrogenase NIBLCNGB_02137 326426.Bbr_0616 5.1e-259 899.8 Bifidobacteriales ko:K07133 ko00000 Bacteria 2HJ52@201174,4D2TQ@85004,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) NIBLCNGB_02138 216816.GS08_03150 2.4e-110 404.8 Bifidobacteriales ko:K07220 ko00000 Bacteria 2IIE4@201174,4D200@85004,COG1392@1,COG1392@2 NA|NA|NA P Protein of unknown function DUF47 NIBLCNGB_02139 326426.Bbr_0618 0.0 1615.9 Bifidobacteriales uvrA3 ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2GNMW@201174,4CZ5X@85004,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate NIBLCNGB_02140 869209.Tresu_0922 8.9e-171 607.4 Spirochaetes Bacteria 2J6KT@203691,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family NIBLCNGB_02141 869209.Tresu_0921 5.4e-99 367.9 Spirochaetes Bacteria 2J6GC@203691,COG0464@1,COG0464@2 NA|NA|NA O PFAM ATPase family associated with various cellular activities (AAA) NIBLCNGB_02142 1280673.AUJJ01000025_gene1325 5.1e-12 77.4 Butyrivibrio Bacteria 1V8BM@1239,24KZ3@186801,2AWWP@1,31NU7@2,4BZI5@830 NA|NA|NA NIBLCNGB_02143 1688.BCUN_1887 1e-47 196.4 Bacteria Bacteria COG3209@1,COG3209@2 NA|NA|NA M self proteolysis NIBLCNGB_02144 1410632.JHWW01000001_gene953 2.1e-44 186.0 unclassified Lachnospiraceae Bacteria 1V6J8@1239,25272@186801,27TP6@186928,2C08P@1,2ZC0W@2 NA|NA|NA S Domain of unknown function (DUF4417) NIBLCNGB_02146 326426.Bbr_0312 1.7e-219 768.5 Bifidobacteriales Bacteria 2GM8F@201174,4D01G@85004,COG3328@1,COG3328@2 NA|NA|NA L Transposase, Mutator family NIBLCNGB_02147 216816.GS08_03180 4.2e-189 667.2 Bifidobacteriales ko:K02529,ko:K03604 ko00000,ko03000 Bacteria 2IEHE@201174,4D2DY@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor NIBLCNGB_02148 216816.GS08_03175 1e-141 509.6 Actinobacteria ko:K03306 ko00000 2.A.20 Bacteria 2IDX1@201174,COG0306@1,COG0306@2 NA|NA|NA P Phosphate transporter family NIBLCNGB_02149 216816.GS08_03170 2.2e-139 501.9 Bifidobacteriales ugpA ko:K02025,ko:K05814,ko:K10118,ko:K15771 ko02010,map02010 M00196,M00198,M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.28,3.A.1.1.3 Bacteria 2GKJI@201174,4D0GQ@85004,COG1175@1,COG1175@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component NIBLCNGB_02150 216816.GS08_03165 3.5e-138 497.7 Bifidobacteriales ugpE ko:K02026,ko:K05815 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 Bacteria 2GMTH@201174,4D29F@85004,COG0395@1,COG0395@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component NIBLCNGB_02151 216816.GS08_03160 6.3e-241 839.7 Actinobacteria ugpB GO:0001407,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0015711,GO:0015748,GO:0015794,GO:0030288,GO:0030313,GO:0031975,GO:0034220,GO:0042597,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098656,GO:1901264 ko:K02027,ko:K05813 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 iEcE24377_1341.EcE24377A_3931 Bacteria 2HP0P@201174,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein NIBLCNGB_02152 216816.GS08_03155 1.3e-149 535.8 Actinobacteria ugpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 2INE1@201174,COG0584@1,COG0584@2 NA|NA|NA C Domain of unknown function NIBLCNGB_02153 216816.GS08_03150 5.1e-97 360.5 Bifidobacteriales ko:K07220 ko00000 Bacteria 2IIE4@201174,4D200@85004,COG1392@1,COG1392@2 NA|NA|NA P Protein of unknown function DUF47 NIBLCNGB_02154 1437610.BREU_1897 3.3e-168 597.8 Bifidobacteriales Bacteria 2GKW1@201174,4D05P@85004,COG2801@1,COG2801@2,COG3415@1,COG3415@2 NA|NA|NA L PFAM Integrase catalytic NIBLCNGB_02155 216816.GS08_09870 1.7e-139 501.9 Bifidobacteriales Bacteria 2I9JH@201174,4D2KU@85004,COG4974@1,COG4974@2 NA|NA|NA L Phage integrase, N-terminal SAM-like domain NIBLCNGB_02158 1095770.CAHE01000089_gene1818 2.5e-60 239.2 Peptoniphilaceae Bacteria 1V8VU@1239,22IK1@1570339,24PY3@186801,COG5527@1,COG5527@2 NA|NA|NA L Initiator Replication protein NIBLCNGB_02160 60520.HR47_00110 2.5e-55 223.0 Lactobacillaceae Bacteria 1UI5D@1239,3FBS7@33958,4ISEB@91061,COG2433@1,COG2433@2 NA|NA|NA S MobA/MobL family # 1986 queries scanned # Total time (seconds): 4.63253903389 # Rate: 428.71 q/s