LOCUS       c00046_JACJLI0..       15143 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JACJLI010000025.1 Ligilactobacillus salivarius strain An453
            An453_contig-110_24, whole genome shotgun sequence.
ACCESSION   JACJLI010000025
VERSION     JACJLI010000025
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2022-06-21 20:22:52
            Original ID  :: JACJLI010000025.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15143
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15143
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2012:5143]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2013..5143
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15143
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15143
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             489..791
                     /locus_tag="ctg46_1"
                     /transl_table=11
                     /translation="MNKIIISKLNNDENKIEWRISNSETGHYLNISISRALEDAMKKKR
                     NLSFNRFESEQINNLSHLVTNIQEDYVLNIDESNISSSYLPLRGIDALSYMKTVE"
     CDS             1049..1927
                     /locus_tag="ctg46_2"
                     /transl_table=11
                     /translation="MYYNAALVLEGGAMRGLYTSGVLDTFLEHDIQFDCVIGVSAGSLN
                     GANFVSKQYQRTYNVNVKYRKDHDYISLARPFKHESIINLDFLFDDHGLDWHNFDNKAY
                     LKSETDFIVVATSLESGKAVMLRNPQPGQDLIDALEASSSMPFISKPHNTSKGLCLDGG
                     IANSIPFDIAQKMGFQKIVVVRTRPRDYRKKPTSFALKRLYSNSFKEYPEFVKTAIRRP
                     EMYNHSVEVLNKLEHNDEIFCLAPKDPVKVGRLEHNTKKMTELYNIGRNDAESNLEAML
                     NYLQKSESLYD"
     CDS             complement(2013..2849)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.4;
                     E-value: 1.5e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_3"
                     /sec_met_domain="Radical_SAM (E-value: 9.3e-34, bitscore:
                     107.7, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSANPLLNPVPTKDGHVVGYVHSLETFGAVDGPGIRFVVFMQGCH
                     MRCKFCHNPDTWKTRVGSQMTTEEVLNKALPYRSFWGDKGGITLSGGEILLQIDFALEL
                     FKMCKEEGISTCLDTCGQPFTRREPWFSKFNELMDYTDILLVDIKHINSDEHKRLTGFP
                     NDNILDMCEYLSSIGKPVWIRHVLIPGITDNDEYLKQLGEYVKENLHNVEKFEVLPYHT
                     MGVHKYHEMGIRYRLEGVEPPTPERVKNAEKLLEVDRYQGYKDWYPGINTLDQQPS"
     CDS             complement(2876..5143)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_4"
                     /sec_met_domain="Gly_radical (E-value: 7.2e-41, bitscore:
                     129.7, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 2e-262, bitscore:
                     862.4, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVEKTQMQNVDVKDAWEGFRGKEWKEEIDIREFIQDNFTPYDGDQ
                     SFLEGPTEATTKLNDKLIDLKLKERAHGGPLEADTKVVSTITSHKPGYLDKSLEKIVGL
                     QTDKPMKRALMPYGGIRMAKGALEAYGFKIDPETDFVFEKLSKTHNQGVFDAYTSEIMK
                     ARHNKIITGLPDAYGRGRLIGDFPRVALYGIDRLIEEKKKDLENCGDGEMTNDIIQMRE
                     EISDQIKALKDMKIMAESYGYDISKPATTAKEAIQWLYFGYLASIKQQNGAAMSIGRID
                     SFIDIYIERDMKRGILTEKEAQELIDQFTMKLRMVCFIRTPAYNSLFSGNPIWATLSIA
                     GMGLDGRHHVTKTSYRFLNTLHNMGAAPEPNITLLWSDRLPESFKHYAASVSIASSTIQ
                     YENDDLMMKTWGTDYYGIACCVSAQPIANGMQFFGARANLAKAVLYAINGGKDELTKQQ
                     VGPAYEPISSEYIDYDEFMKKFDDMMEWIADIYVNALNTIHYMHDKYYYESAQMALKDT
                     LVDRSFATGISGLSVAADSISAIKYGHVKVIRDEDGIAVDFKADHDFPRYGNDDDRVDD
                     IAAWLVKELFTKMSKHHLYRGAKLTTSVLTITSNVVYGKNTGTTPNGRQKGEPFAPGAN
                     PAYGADTTGALASLLSVAKLPYKYATDGISNTFAVTPTTLGHDEKMQEDTLVNMIGGYM
                     RKDGHHLNINVFNRDTLLDAQAHPEKYPTLTIRVSGYCVYFADLTKEQQDDVIARTFHT
                     SM"
     CDS             complement(5455..6039)
                     /locus_tag="ctg46_5"
                     /transl_table=11
                     /translation="LKVTYVLKVKTNFFWDSLNVIRASILGANDGIISVSGIVLGAAGA
                     NLNSKTLLISGLSGMLAGACSMAGGEWISVSTQRDIQEKTMERQSQLENEDCENCPIKL
                     QKNDILMPFHAAASSFCSFIIGAMIPLLTMILARPEHRVVFTLIAMIASLSINAVVCTH
                     NSEVSTSKTILRNVITGLLTTLVTFILGASV"
     CDS             complement(6232..7635)
                     /locus_tag="ctg46_6"
                     /transl_table=11
                     /translation="MISEDIKDIGGQYKYGFKDDIEPIYTTGEGLSEEVVRNISKAKNE
                     PEWMLDIRLAAYEKYKTLKMANFGPDLSELDLDHINYFRRDTDTVARKWEDVPQEIKDT
                     FDRLGVPEAERKYLAGSSAQYESEVVYHNMKEDFAKKGIIFMDTDSAVQEYPELVKKYF
                     GKLIPADDNKMAALNTAVWSGGTFIYVPKGVKVETPIQSYFRINAGNSGQFERTLIIVD
                     EGASVNYVEGCTAPNYSQDSLHAAVVEVNVLKDAYCRYTTIQNWSNNVYSLETKRARAL
                     ENATMEWVDGNLGSKVTMKYPSIYLDGEGAHGNMLSIAFAGKGIDSDTGARMIHNAKNT
                     YSSTVSKSLCKDGGIADYRGYVRFNRDSDGSFAHVECDTIIMDDESSSDTIPFNEVLNS
                     NVSMEHEAKVSKISEDQLYYLMSRGISEEKATEMIIMGFVEPFTKELPMEYAVELNRLI
                     EYQMDGSVG"
     CDS             complement(7628..8077)
                     /locus_tag="ctg46_7"
                     /transl_table=11
                     /translation="MSNLNNLYRQAILEEANHPRHKGKLENKSVEVELRNPTCGDVITL
                     TALIEDNKIKDIAFDGYGCTISQSSASIMTNEVLNKDFDTIKNMVLSFSDMITKEVKPD
                     RKVLGEAIILEGVKQFPARIKCAMLSWKAIYQLIEKYEGKGEKND"
     CDS             complement(8074..9303)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_8"
                     /sec_met_domain="Aminotran_5 (E-value: 2.7e-161, bitscore:
                     527.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKKTSDLRKDFPLLETKMNNQPLTYLDSAATSQKPKQVIDEIAD
                     YYNKYNSNIHRGVYNLAVETTDKYENVRHKVANFINAYRDEEVLFTKGTTQSLNWIAQG
                     YVRYNLHEGDEIVTTYMEHHSNIVPWQAIAQEKNLKVKYVTLTKEGKLDLDDLKQKITD
                     KTKIVAVTHVSNVLGTINPIKEIAAIVHQSNAILVVDGAQSVPHLPVDIQDLEADFYVF
                     SGHKMLGPTGIGVLWGKYELLEKMHPLEYGGEMIDSVTTEKSTFKEIPWNFEGGTQNIE
                     GVLGLGAAIDYLEEVGMENVARNDEDLQKYALEKLANIKTVEIYGPKDPDQRCGVVSFN
                     LKGIHPHDVATFLDADGIAVRAGHHCAQPLMDWLGVSATLRASFYFYNTYEEIDKLVDS
                     LKKVEEFFQI"
     CDS             complement(9287..10537)
                     /locus_tag="ctg46_9"
                     /transl_table=11
                     /translation="MKQLSIDELIELRKEPEWFRAKRNEAKQLIETTKLPSFQKIKYHD
                     WDINVDGTSVIDDQPKFDTNADVYQYASNKAQIKLPSEFLDKGVIVEDFEDALVNHEDI
                     MKKYFMEKGLKMDDNRLLAEHVANLQSGVLVYVPKNVDLETPLTCEYIQNSRVEEDYVH
                     HVLIVTEANSSLSYVERLKTDGDKSNTANIVVEVIAGDGSRIHFASVDNLSKNTTAYMN
                     RRGYLQRDSKIDWAMGMMNSGLTIGDFDSDLVGDGSHAELKVVGISTSDQIQGIDTRVT
                     NIGKNTIGHILQHGVALDASELTFNGIGHVMKRSKGSDAQQESRILMLSPQARGDANPI
                     LLIDDNDVTAGHAASIGRVNPEQLYYLMSRGLQKRLAEKLVIRGFLAPVLDEIPLKEIR
                     NEFSELIERKVSYDEEN"
     CDS             complement(10550..11140)
                     /locus_tag="ctg46_10"
                     /transl_table=11
                     /translation="LNGKSIIDLPVDERARMGLFLAMQYPQEIPGVTNAEFVKSAINAR
                     RPKDDPIPLMDFIKRLDETLETLDMSEEMADRYLNEGFSGGEKKRNEIMQMMMIRPEFA
                     ILDEIDSGLDIDALKVVSRGVNQMRGDNFGSLIITHYQRLLNYIVPDYVHVMMDGQLVK
                     TGGPDLAIRLEKEGYAKLRDELGLDIKLVDENA"
     CDS             complement(11591..13225)
                     /locus_tag="ctg46_11"
                     /transl_table=11
                     /translation="MKRIKAIITGIFISLTAVLLVACGKSTSENSKQVLNLSTTGPLDT
                     IDISKSTGYGQTGNVFESFYRLGKDGKVTPGLAKSGQVSQDGKTWTFTLRDAKWSNGDK
                     ITAQDFVYSWRRTIDPKTASPYAYLFYDVKNAQAINEGKMSADKLGIKAEGDNKVVITL
                     DRPISYFKVLMTYPLFGPQNEKVVQKYGKKYGTNSKYMVYSGPFKVKDWNGTSDKWSFV
                     KNDQYWDKKVVKLQKINYQVVKNTNTGYQLFQQGKLDLTPLSSEQVKNLHNKPEFKQYS
                     YSYVAYLDYNFNDSNEVNRKALNNKNIRLALSLAIDRKTLTKKVFGDGSNVPTGFVASD
                     LATNPKTGKDFAAEQKVDNTVDYNEKLAKEYWKKGLQEIGEKNLSFTILASNEMANNDA
                     LTQYLQSQYTKVLPGIKVSVQNIPGNSALSKARKGNYDIYVSGWGGDFKDPITFMQIPV
                     TGTSYNYGKYSNKEYDALIEKAQNEDANDTNKRWEDLVKAARIFNADQGVTPLYQQTTS
                     YMQNTKVKGIIQNTAGTQWNYKYAYIK"
     CDS             complement(13754..14035)
                     /locus_tag="ctg46_12"
                     /transl_table=11
                     /translation="MKPMYISINSEKTGANLKSLFKNNGYSVRDIQSVMGFENPQSIYK
                     WLSGRSLPSLDNLVILSKVLHTTIEDILVVDGDVVFLFHLTWTIHLNR"
     CDS             14473..14664
                     /locus_tag="ctg46_13"
                     /transl_table=11
                     /translation="MSPLASLYTTFFRCSQLVLPKWKLEKINVSVYFVIVVIKRRMARR
                     LVTPYPLASSVHLYTNKA"
ORIGIN
        1 gattattaaa atcaaaatta ggaaattaat ttccaataaa ataaaaagtt actttaactt
       61 tctaaaaaat gtacgttttt cataaagatg gatagagaga aaaccaaaca gtgtaatata
      121 atctcattat agctttattg agtaattttg atgtttatca aaaatcatat ttttttagaa
      181 agttaaagta actttttatt ttattggaaa ttaatttcct aattttgatt ttaataatct
      241 gtctacgatc tgttgttttt aaagacaaat ttgtattata taactgattc cattcaataa
      301 tcctttatca aaacaattat attaacatac caatccttat attatatgga tattcaactt
      361 tttaaataag taaaaacaat tatttactta tatttttaat tttacacttg cttttattcg
      421 taaataagag tagagttata cttgtaagtt aaggaaagca tttacattta ttaaggtggt
      481 aattatatat gaataaaatt attattagca agttaaacaa tgacgaaaat aagattgaat
      541 ggcgtatttc taacagtgaa actggacatt acttaaatat ttcaatttcc cgtgcattag
      601 aagatgctat gaagaaaaag cgtaatttat cctttaaccg ctttgaatct gaacaaatta
      661 acaatttgtc tcacttagtt acaaacattc aagaagacta tgttcttaat attgatgaat
      721 ccaatattag ctctagttat ttaccattaa ggggtatcga cgcattatca tatatgaaaa
      781 ccgtcgaata agtgattata agtattaaat taagttgtta ttttaatact tatcttggat
      841 atatttaggt attcttaatt gattaaagat ttggctgtca acaatctcta ttttaatgat
      901 agaggttgtt tttttattaa atgttttaca gttgcattgt ttttgactaa ttaaatattt
      961 aaattctctt attattcctt tgtattcttg ctatctctac tttttaggtt tatattaatt
     1021 ctagttattt ttcgaaagga atggttacat gtattacaat gcagctctag ttttagaagg
     1081 tggtgcaatg cgtggcctct atacttctgg cgttctagat acctttttgg aacatgatat
     1141 tcaatttgat tgtgttattg gagtttctgc agggtcccta aatggtgcta atttcgtttc
     1201 aaaacaatat caaagaactt ataatgtaaa tgttaaatac cgtaaagatc atgactatat
     1261 ctctttagca cgccctttta agcatgaaag tattattaac ttagatttct tatttgatga
     1321 tcatggatta gattggcata atttcgataa taaagcttat ttaaagtctg aaactgattt
     1381 tattgttgta gctacttctc tagaaagcgg aaaagctgtg atgctacgta atccccaacc
     1441 tggccaagac ttaattgatg ctttagaagc ttcttcatct atgcctttca tctcaaagcc
     1501 acataatact tctaaaggac tttgtctaga tggtggtatt gctaactcta tcccttttga
     1561 tatcgctcaa aaaatgggtt ttcaaaaaat tgtagttgtt cgtactcgtc cacgtgatta
     1621 tcgcaaaaag cctactagtt ttgctttaaa acgcctctac agtaatagct tcaaggaata
     1681 cccagaattc gttaaaacgg ccatcagacg ccctgaaatg tataatcatt ctgttgaagt
     1741 tttaaataaa cttgaacaca acgacgaaat tttttgttta gcacccaagg atccagttaa
     1801 agttggtagg cttgaacaca atactaaaaa gatgactgaa ctctataata taggtagaaa
     1861 tgatgctgaa agtaatcttg aagcaatgct taactatctt caaaaaagtg aatccctata
     1921 tgactaaaaa tacattttaa aaccaaaaaa catggtatct acttagcaaa actaagcgat
     1981 accatgtttt tattttatat ttgccaattt agctagcttg gttgttgatc caaagtatta
     2041 atgcctggat accaatcttt atatccttga tatctatcta cttctagcag tttttcagca
     2101 ttttttactc tttctggcgt aggaggctca acaccttcaa gacgatatct gatacccatt
     2161 tcatgatact tatgaacgcc cattgtatga taaggtaata cttcaaattt ttcgacatta
     2221 tgaagatttt ccttaacata ctcgcccaat tgtttcaagt attcatcatt atccgtgatg
     2281 cctgggataa ggacatgacg aatccaaaca ggtttcccta tgctagaaag atattcgcac
     2341 atatccaaaa tattatcatt tgggaatccg gttaatctct tatgttcgtc cgaattaata
     2401 tgcttgatat caactaatag aatgtcggta tagtccatta actcattgaa cttactaaac
     2461 caaggttctc ttcttgtaaa tggctgtcca caagtgtcca aacaagtgct aataccttct
     2521 tccttgcaca tcttgaataa ctctagtgca aaatctattt gcaatagaat ttcaccacct
     2581 gataaagtta ttccaccttt gtcgccccaa aagctacgat aaggaagtgc cttatttaga
     2641 acttcttcag tcgtcatttg tgaacctacc cttgttttcc aagtgtccgg attgtgacag
     2701 aacttacacc tcatatggca accttgcata aaaacgacaa aacgtatacc tggtccatcg
     2761 acagccccaa aagtttccaa agaatgtaca tagcctacga catgaccgtc tttagttgga
     2821 actggattca ataaaggatt agcactcatt ctctccacct actctcttct aaatattaca
     2881 ttgaagtatg gaaggttctt gcaataacgt catcttgttg ttctttagtt agatcagcaa
     2941 agtatacaca gtaacctgaa acacgaattg ttaatgttgg atacttctct ggatgtgctt
     3001 gagcatctaa taaagtatct ctattgaata cattaatatt caaatgatga ccatcttttc
     3061 tcatatagcc tccgatcatg tttactaatg tatcttcttg catcttttca tcatgaccca
     3121 atgttgttgg tgttacagca aatgtattag aaataccatc tgtagcatac ttgtatggta
     3181 atttagcaac agataataat gatgctaaag cacctgttgt atctgctcca tatgctgggt
     3241 tagcacctgg tgcaaatggt tcaccctttt gacgaccatt tggagtagta cctgtgttct
     3301 taccataaac aacatttgaa gtaattgtaa gaacggatgt tgttaactta gctccacgat
     3361 atagatgatg cttgctcatc ttagtaaata gttccttaac aagccatgca gcaatatcgt
     3421 caacacgatc atcatcgtta ccataacgag ggaagtcatg atctgcttta aagtcaacag
     3481 caataccatc ttcgtcacga attactttaa catgtccgta cttgatagct gaaattgagt
     3541 cagcagcaac agacaatcca gaaatacctg tagcaaagct acgatctact aatgtatctt
     3601 tcaatgccat ttgtgctgat tcatagtaat acttgtcatg catgtaatga attgtgttca
     3661 aagcatttac ataaatatca gcaatccatt ccatcatgtc atcgaatttc ttcatgaatt
     3721 catcgtagtc aatgtattct gagctaattg gttcgtatgc aggacctact tgttgttttg
     3781 taagttcatc cttaccacca ttgatagcat acaatacagc cttagctaga tttgcacgag
     3841 ctccgaagaa ttgcatacca tttgcaattg gttgtgcaga tacacagcaa gcaatgccat
     3901 agtagtctgt tccccatgtc ttcatcatta agtcatcgtt ttcgtattga attgtagaac
     3961 ttgcaataga tacacttgca gcatagtgct taaatgattc aggcaaacga tcagaccaaa
     4021 gtaatgtgat atttggttct ggtgcggcac ccatattatg caatgtattt aagaaacgat
     4081 atgatgtctt agttacatgg tgacgtccat ctaagcccat accagcaatt gataatgttg
     4141 cccagatagg gttacctgag aatagtgagt tgtaagctgg tgtacgaatg aagcatacca
     4201 ttctcaattt cattgtgaat tggtcaatta attcttgtgc ttctttttca gttaaaatac
     4261 cacgcttcat atcacgttca atgtaaatat cgatgaatga atcgatacga ccaatagaca
     4321 tagcagcacc attttgttgt ttaatagatg ctaaatatcc aaagtataac cattgaattg
     4381 cttctttagc tgttgtagct ggtttggaaa tgtcatagcc ataagactca gccataatct
     4441 tcatatcctt taaggctttg atttgatcag aaatctcttc acgcatttgg attatgtcgt
     4501 tagtcatctc accatcgcca caattttcca aatctttttt cttttcttcg attaaacgat
     4561 caataccata caatgcaaca cgtgggaagt caccaatcaa acggccacga ccatatgcat
     4621 ctggtagtcc agtgataatc ttgttgtggc gagctttcat gatttcgctt gtgtatgcat
     4681 caaatacacc ttggttatgt gtcttagata gcttttcaaa tacgaagtct gtttctggat
     4741 caatcttaaa tccataagct tccaaagcac ctttagccat tctgatacca ccatatggca
     4801 taagtgcacg tttcataggt ttatctgttt gtaaaccaac aatcttttct aatgacttgt
     4861 ctaaataacc tggtttatga gatgtaattg ttgatactac ttttgtatca gcttcaagag
     4921 gtccaccatg tgcacgttct tttaatttta agtcgattaa tttatcgttt aacttcgttg
     4981 tagcttcggt tggtccttca aggaaagatt gatctccatc atatggagtg aagttatctt
     5041 gaataaattc acgaatatca atttcttctt tccattcttt tcctctaaat ccttcccaag
     5101 catcttttac atcaacgttt tgcatttgag tcttttcaac catacccaaa gcctcctttg
     5161 tgatttttaa gaaaacgttt tctacactgt taatactaca ccttagttaa attaaattca
     5221 atgaaaaatt gttcacaatg ttttttattt tcaaaaaata ttataaacgc tatcatttat
     5281 tttaatcatt ataaatgtta atatgacaat atttttgaca acagtttata aactttaaaa
     5341 atgtgattta tgtatcaaaa tataaatttc attaatttta ttttagaatt tcttaaaatt
     5401 acaaaaaaag accctatacc caataaaatt taggtatagg acctttaaaa gtatctatac
     5461 tgacgcccct aaaataaagg taactaacgt cgttaacaat ccggttataa catttcgtaa
     5521 aattgttttg ctagttgaaa cctcagagtt gtgtgtacaa actactgcat taattgataa
     5581 tgaggcaatc atcgcaatta atgtaaatac cacgcgatgt tctggtcttg ctagaatcat
     5641 cgtcaataat ggaatcattg ccccaattat aaatgagcag aaagaactgg ctgcagcatg
     5701 aaacggcatt aagatatcat tcttttgcaa ttttatcgga caattttcac agtcttcatt
     5761 ttccaactga ctttgtcttt ccattgtctt ttcttgaata tctctttgag tacttacaga
     5821 tatccattct ccaccagcca ttgaacaagc tccagctagc atgccagaca aaccactgat
     5881 taaaagggtc ttactattaa gattagcccc tgcagcacct aacacgattc cagatactga
     5941 aataatccca tcattggcac ctaaaatact agcccttata acatttaagc tatcccaaaa
     6001 aaaattagtc ttaactttca atacatacgt aactttcaat ttgtacactt cctcacgaaa
     6061 tataaaaata ataccgtttt tatatacata tttaaattat ataaaccgct ttcattacga
     6121 ttaaattata catcatatga gtaattagta ctaatttagc aaaatttata attatataca
     6181 tgtttcacaa taatataaaa aagcatactt aaaaagcatg cttttttata attaacctac
     6241 actaccatcc atttgatact caatcaatct attcaattcg actgcatatt ccattggtag
     6301 ttctttagta aatggttcaa caaatcccat aataatcatt tcagtagcct tttcttcaga
     6361 aatacctcta ctcatcaaat agtaaagctg atcttcagaa attttagaaa ctttagcttc
     6421 atgttccatt gaaacattac tatttaatac ttcattaaat ggaattgtat cacttgaaga
     6481 ctcatcatcc ataatgatag tgtcacattc aacgtgcgca aacgaaccat cactatctct
     6541 attaaacctt acatacccac gatagtcagc aattcctcca tctttacaga gagattttga
     6601 tacagttgac gaatatgtat tcttagcatt atgaatcatt cttgcaccag tatcagagtc
     6661 aatacctttg cccgcaaatg caatagataa catatttcca tgtgcacctt cgccatctaa
     6721 atagatactt ggatatttca tagttacttt agaaccaagg ttaccgtcta cccattccat
     6781 agtagcattt tccaaagctc tggcacgttt tgtttccaaa ctatatacgt tgttggacca
     6841 gttttggatt gttgtataac ggcaataagc atccttcaaa acatttactt caacaactgc
     6901 cgcatgtaag gaatcttgtg aataattagg agcagtacaa ccttctacat agttaacact
     6961 agcaccttca tcgacaatga ttagtgttct ttcaaattgt cctgaatttc cggcattaat
     7021 tcggaagtaa ctttgaatag gtgtttcaac ctttaccccc ttaggtacgt aaataaatgt
     7081 tcccccagac caaacagctg tattaagagc tgccatttta ttatcatctg ctggtattaa
     7141 ctttccaaaa tatttcttta ctaattctgg atattcttga actgcagaat ctgtatccat
     7201 aaatatgata ccttttttgg caaagtcttc tttcatatta tggtaaacaa cttccgattc
     7261 atattgagca gaagaaccag ctaaatattt acgttcagct tctggtacgc ctaagcgatc
     7321 aaaggtatct ttaatttctt gtggaacatc ttcccatttt ctagctactg tatcagtatc
     7381 acgtctaaaa taattaatat gatctaaatc caattctgac aaatctggtc caaaattagc
     7441 catcttcaaa gtcttgtact tttcataagc agccaatcta atatccaaca tccattcagg
     7501 ttcattttta gctttagaaa tatttcttac aacttcttca ctaagacctt caccagttgt
     7561 atatattggt tcaatatcat ctttaaaacc atatttatat tggccaccaa tatcttttat
     7621 atcttcacta atcattcttt tcaccctttc cttcatactt ctcaataagt tgataaattg
     7681 ccttccatga taacattgcg catttaattc gagctgggaa ttgtttaacc ccttctaaaa
     7741 ttattgcctc acctaaaact tttctatcag gttttacttc ttttgtaatc atatcggaaa
     7801 atgacaatac catgtttttt attgtatcga agtctttatt taatacttca tttgtcataa
     7861 tacttgcgga tgattgagaa attgtgcaac catagccatc aaaagcaata tcttttatct
     7921 tattatcctc aattaatgca gttaaggtaa taacatcgcc acaagttgga tttctcaatt
     7981 caacttcaac acttttattt tctaatttac ctttatgtcg tggatggtta gcttcttcta
     8041 aaattgcttg tcgatataaa ttatttaaat tactcatatt tggaaaaatt cctctacttt
     8101 ctttagagaa tctactaatt tgtcgatttc ttcataagta ttataaaaat agaaacttgc
     8161 tctcaaagta gcactcacac ctaaccaatc cataagtggt tgtgcacaat ggtgaccagc
     8221 tctaactgca attccatcag catctaaaaa agttgctaca tcgtggggat gaataccttt
     8281 caaattaaag gatactactc cacatctttg atcaggatct ttgggaccat aaatttcaac
     8341 agtcttaata ttagctaact tttcaagtgc atacttttgt aagtcctcat cgtttcgagc
     8401 cacattttcc attccaactt cttctaaata atcaatcgca gcaccaaggc ctagtacacc
     8461 ttcaatattt tgcgttccac cttcaaagtt ccaaggaatc tctttgaatg ttgatttttc
     8521 agttgttaca ctgtcaatca tttctccacc atattctaaa ggatgcattt tttctaagag
     8581 ttcatacttt ccccatagaa caccaattcc agtaggtcct aacatcttat ggccagaaaa
     8641 tacataaaag tctgcttcta aatcttgtat atctactggt aaatgtggta cagattgagc
     8701 accatcaact actaaaattg cattactttg atgaacaata gctgcaattt ctttaattgg
     8761 attaattgtt cctaaaacgt tagaaacatg agtaactgct actatctttg ttttatcagt
     8821 aatcttttgc tttaaatcgt ctaaatcaag tttaccttct ttagttaaag ttacatactt
     8881 tacctttaga ttcttttctt gtgcaattgc ttgccatgga acaatgttac tgtgatgctc
     8941 catataagtg gtgacaattt catcgccttc atgcaagtta tatctaacat aaccttgtgc
     9001 tatccagttc aaactttgag ttgttccctt ggtaaaaagt acttcctcat cgcgataagc
     9061 attaataaaa tttgccactt tatgtcttac attttcatat ttatcagttg tttcgactgc
     9121 taaattgtag acaccacgat gaatattact attgtattta ttatagtagt cagcaatttc
     9181 gtcaattact tgcttaggct tttgcgaagt agctgcacta tctaagtaag ttaaaggctg
     9241 attgttcatt ttagtttcta aaagaggaaa atcttttctt aaatcactag ttttcttcat
     9301 cataacttac ctttctttca atcaattcac taaactcatt gcgaatttct ttcaaaggta
     9361 tttcatctaa aacaggagct aggaaacctc taattactaa tttttcagct aaacgtttct
     9421 gtaagccacg actcattaag taatataatt gttcaggatt tacacgacca atacttgccg
     9481 catgtcctgc agtaacatca ttatcatcaa ttagcaaaat tggattagca tcccctctag
     9541 cttgtggaga taacattaaa atacgacttt cttgttgtgc atcagatcct ttacttctct
     9601 tcattacatg tccgatgccg ttgaaagtta attcggatgc atctaaagca acaccatgtt
     9661 gtaagatatg accgattgta ttctttccaa tatttgtaac tcgtgtatca attccttgaa
     9721 tttgatcact tgttgaaata cctacgactt ttaattcagc atgagagcca tcgccaacta
     9781 aatcagaatc aaaatcaccg attgttaaac cagaattcat catacccatt gcccagtcaa
     9841 tcttggaatc tctttgtaag tatccacgac gattcatata agcagttgtg ttcttactta
     9901 aattatcaac actagcaaag tgaattcgac ttccatcacc agcaataact tcaactacaa
     9961 tattagctgt attactctta tcaccatctg tttttaaacg ttctacataa gatagtgaac
    10021 tatttgcttc tgtaacaatt agtacatgat gaacataatc ttcctcaact cgtgaatttt
    10081 gaatatattc gcatgttaat ggtgtttcta agtctacatt tttaggtaca taaactaaaa
    10141 ctccactttg aagatttgct acatgttctg ccaacagacg attatcgtcc atttttagtc
    10201 ctttttccat aaagtatttc ttcataatat cttcatggtt aaccaaagca tcttcaaaat
    10261 cttcaacaat tacaccctta tcaagaaatt ctgatggtaa cttaatttgt gccttattac
    10321 tagcatattg atagacatca gcgttagtat caaatttagg ttgatcatca attacactcg
    10381 tcccatcaac atttatatcc cagtcatgat acttaatttt ttggaaacta ggcaatttag
    10441 tagtttcaat taattgttta gcttcatttc gcttagctct aaaccattcg ggctcttttc
    10501 gaagttcaat caattcatct atggataatt gtttcattgt acaagccccc taagcatttt
    10561 catcaactaa tttaatatct agtccaagtt catcacgaag ttttgcgtat ccttcttttt
    10621 ccaaacgaat tgccaaatct ggaccaccag ttttgacaag ttggccatcc atcataacat
    10681 gtacataatc tggaacgatg tagttcaaga gtctttgata gtgagtaata atcaaagatc
    10741 caaaattatc gccacgcatt tggttgacac cacgagaaac gactttaagt gcatcaatat
    10801 ctagtccaga gtcaatttca tctaatattg cgaattcggg tctgatcatc atcatctgca
    10861 taatttcatt acgtttcttt tcaccaccag aaaagccttc gtttaaatat ctatcagcca
    10921 tttcttcaga catatccaat gtttctaatg tttcatctaa acgtttgatg aaatccatta
    10981 aaggaatcgg atcatcttta ggacgacgag cattgatcgc acttttaaca aattctgcat
    11041 tagttactcc tggaatttct tgtggatatt gcatcgctaa aaatagtccc attctagcac
    11101 gttcatcaac tggtaaatca atgatacttt taccattcaa taaaatatct ccctttgtaa
    11161 tcttgtaagc aggatctccc ataatagttg aagaaagtgt tgatttccca gtaccattcg
    11221 gacccataat tgcatgaatt tcaccagtcg acatctttaa attaacgccc tttaaaattt
    11281 cctttccttc aacagttaca tgtaaatctt taacttctaa tactgacatt taaatcacca
    11341 ctataaaata gttacctttc ctggaatttt cttatcaata acattataag acaaattacc
    11401 taacttaacg attggattta agtattttta caatatattc ccttaaattt atttgtaatt
    11461 aagtaataat ctttataata agtttacaaa tatagaataa cgcttacata caacataatc
    11521 aatactctta tacaaattat ttagcacaac ttaaaaactc gcctagaaac cattctagac
    11581 gagtttttac ctacttaata taagcgtatt tgtaattcca ttgtgtacct gcagtatttt
    11641 gaataatacc cttcactttt gtattttgca tataagatgt tgtttgttga tatagaggcg
    11701 ttacaccttg atcagcatta aagattcgag ctgcttttac taaatcttcc caacgcttat
    11761 tagtatcatt ggcatcttca ttttgcgctt tttcaattaa agcatcatat tctttattag
    11821 aatattttcc ataattgtac gaagttcctg taactggaat ttgcatgaat gtgattggat
    11881 ctttgaagtc tccaccccaa cctgatacat aaatatcata gttaccttta cgagctttag
    11941 ataatgcact atttccaggg atattttgta cggaaacctt aattcctggc aatacctttg
    12001 tatattgtga ttgtagatat tgagttaaag catcattatt agccatttca ttagaagcta
    12061 gaattgtgaa acttaagttc ttttcaccaa tttcttgtaa tcctttcttc caatattctt
    12121 tagctaattt ttcattatag tcaactgtat tatctacttt ttgttctgca gcgaaatctt
    12181 tacctgtttt cggattagta gctaaatcag atgctacaaa accagttggt acattagatc
    12241 catcgccgaa aactttcttt gtaagtgtct ttctgtcgat cgctaatgat agagctaatc
    12301 taatattttt attatttagt gccttacgat ttacttcatt agaatcatta aagttgtagt
    12361 ctagatacgc aacataagaa taagagtatt gtttgaattc tggcttgtta tgtaaattct
    12421 taacttgctc actagataat ggtgttaaat ctaacttgcc ttgttggaat aattgatagc
    12481 ctgtattggt attcttaact acttgataat taatcttttg tagtttcact acttttttat
    12541 cccagtattg atcgttcttt acaaatgacc acttatctga ggtaccattc caatctttaa
    12601 ctttaaatgg tcctgaatac accatgtatt tagaattagt tccatatttc ttaccatact
    12661 tttgtactac tttttcattt tgtggtccaa ataatggata tgtcattaag actttaaaat
    12721 atgatatagg tctatctaat gtaataacaa ccttgttatc accttcagcc tttattccta
    12781 acttgtcagc tgacatttta ccctcattaa tagcttgagc attctttaca tcatagaaca
    12841 aataagcata tggcgaagct gtcttaggat caattgttct tctccaggaa tatacaaaat
    12901 cttgagcagt aatcttatca ccgttactcc actttgcatc tcttaaagta aaagtccatg
    12961 ttttgccatc ttgtgaaact tggccacttt tagctaatcc aggagttacc ttaccatctt
    13021 tacctaaacg ataaaaactt tcaaaaacat tcccagtttg accataaccg gtagacttag
    13081 aaatatcaat ggtatccaat ggtccagttg tacttaaatt taaaacttgc ttagaatttt
    13141 cactagttga tttaccacat gcaactaaca aaactgcggt taaacttata aatattccag
    13201 taataattgc tttaattctt ttcatcttta ttttctcctt tatgtaagat atgtttttaa
    13261 tctataaaca gttcatcatc catccttcca gataaacaaa aaggacttgc aactccaaaa
    13321 aattagaatc gcaagtccag ttattattat ctcatataat ctaactgatt aaattaatct
    13381 gcatcggtac cgataataaa tatatacagt ttaatccaat cttggaagtg tgaatctaat
    13441 tttctgcata ccaaaattca tgttgcctac tggacaacat gttaccaaac aacagcattg
    13501 tgtattgata aagtttgaca tagtgattca cactcctctc atttctttaa ccaaatcata
    13561 taaccttact atacttttgt caataaattt taattataag tttgcatttt ctaatttttg
    13621 gcaaaaataa tattacttat ttaataaact ctctaattca gctaaatttc ttgctcgttc
    13681 caatttagaa tcatttaaat catctatcat ttctaaaata taatgattta ttctatatgt
    13741 ttcctttcaa ttattatcta tttaaatgta tggtccaagt taaatggaat aaaaaaacaa
    13801 catccccgtc aacaacgagg atgtcttcga ttgtggtatg tagaacctta ctgagaatga
    13861 ctaagttatc caaactaggt agtgatctac cagataacca cttataaatg gattgtgggt
    13921 tttcaaatcc catgactgat tgaatgtcac gtacactgta cccattgttt ttgaataaac
    13981 tttttaggtt agcaccagtt ttttctgaat ttatcgaaat atacattggc ttcatgtaat
    14041 cacctcaatt taattataca tacctctaac actttatacc aaaaatagcc aacgcaaaat
    14101 ttgcattgac taaaaattat gtaaaccgac gcgtattggt ttacgcggga tactcttgta
    14161 tctggactta ttagactact gaatcagact agcacatcat ggctagcaac ttccatgacc
    14221 tagtccgcat ttcaagttca gggcatagac cttttcctat ccaattttca ccaaacatgt
    14281 gcaatgttcc agttaatgta atattgtcga ttttggctac tcaaatctta ctcgtcagtt
    14341 atagctgtgt caccacaact tcacgacacg aattcttagt tgatattttt ctttggttcc
    14401 taaggtaatc agccttaatt aactgagatg gtatattgcg aatccctgac gacaagtgtc
    14461 ttagtttcag atatgagtcc ccttgcttct ctctacacaa ctttttttcg ttgctcccaa
    14521 ttagtactac ctaagtggaa attagaaaaa ataaacgtat ccgtatattt cgtcatagta
    14581 gttattaaga gacgtatggc taggcggctt gtcacacctt atccactagc ttcatcggta
    14641 cacttatata ctaacaaagc ttaggtcatt aaactataaa ctgttaggtt aatttggggg
    14701 atttcactgc aactattaaa atagaatttt gtattctaac tgttatttga agccattaat
    14761 tctgcttgct ctatcacagt ttctactgcc tgcttttgaa aatcaggtgg atagccatat
    14821 tttctaagta atcttcgtac ttctcttcgc atcttagctt ggacactttc tcgtttttcc
    14881 caatctattc cagcttctct ttgtacgact tttactaatt ctttagcaat aagctgtagt
    14941 gtctcttcac ctaacatttc cactgctttc ttatggtcag ctaaagcatc ataaaaagct
    15001 atttcttctt gcgtcaatcc aagatcttca cctttgtttt gttgttctct aattttttta
    15061 gcaatttcta taagttgacg aataactagt tcacttgtta taccacgatt attgtagtca
    15121 tcaatggatt tctttaacat ttc
//
