LOCUS       c00021_JAAONQ0..       13045 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAAONQ010000006.1 Lactobacillus acidophilus strain BCRC 12255
            Scaffold6_1, whole genome shotgun sequence.
ACCESSION   JAAONQ010000006
VERSION     JAAONQ010000006
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-19 19:47:31
            Original ID  :: JAAONQ010000006.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 53329
            Orig. end    :: 66374
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13045
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[58329:61374]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8045
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..13045
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13045
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             917..1093
                     /locus_tag="ctg21_58"
                     /transl_table=11
                     /translation="MKKLKVMNNGELEKVIGGSLYEMKNSVPRLLGPDGMEGSMGGSTG
                     GIQSFRHFPGFGR"
     CDS             1149..1775
                     /locus_tag="ctg21_59"
                     /transl_table=11
                     /translation="MRTRIGRMFFRYKRHRLSTWSALGMLLFGVATLALWIFNMLLFLQ
                     FVGYAATIYYIIDIEAGYAEEKVIGNSQHRLSKSDQFWLGLAQTVTAIIGIAELAVLIY
                     CQVTNYYHFMLSAVFLTGLYFTYWTCLYGLSIYQVKRRVNIAARKWLIGEIVALSVMAA
                     VMVRIYFVQNWVFFVIVIGIAIIEWIVSWRNYYVIKNGDRNAMGY"
     CDS             1947..2108
                     /locus_tag="ctg21_60"
                     /transl_table=11
                     /translation="MQEWKKTTLSDNELIDVIGGSAKSYIRRLGPDGGYGGRESKLIAM
                     ADMIRRRI"
     CDS             2221..2412
                     /locus_tag="ctg21_61"
                     /transl_table=11
                     /translation="MKLRQEQLNRKELSQVIGGRRDMILVALPHAVGPDGMPGSGRGGG
                     AQMRAIGSIPPWRPNWWK"
     CDS             2543..2686
                     /locus_tag="ctg21_62"
                     /transl_table=11
                     /translation="MKKKVVKKTVLKEKELTKVVGGKKAPISGYVGRGLWENLSNIFKH
                     HK"
     CDS             2693..4015
                     /locus_tag="ctg21_63"
                     /transl_table=11
                     /translation="MVLYLSIVQFLLSSAIDLWMFLKITRIKLNINLKLGLTLVVITIG
                     SIISIILDEYGGLLLANISEIIGFYVIYKKKNNKILVAGAIVFVCTLDLFINIILAFAA
                     VFIKVEGYMSIILLFVEAWIVKKYNKNIYSTLVGQNKKSFLYILCYIFLSSEIVLLIIL
                     LTKSYNAFYTVAMVLFALQIIFSIVAYHEIVSIQQELLNKQKQKEILDNQHQLEEYASY
                     LEKSEDDLRAFRHDYKNILNSLKVSAQEGNVKEVIQKLDKYTETNLNSKALLKYKDVNH
                     IYVKSIKSIIISKLTELYNLNIPYNFECRSNIHNLPDHVNELDLVRIIGITFDNAIEES
                     KALVAEKHDIRSAEVQIMVYSDGPDEFEFEIRNKIQNKKISTSQIQQRGFTTKKDHKGL
                     GLANIKEIEGKYPDMSISYTIQDGWFDFYMTIDTEDGEDDE"
     CDS             3999..4808
                     /locus_tag="ctg21_64"
                     /transl_table=11
                     /translation="VKMMSKFPIIVCDDDKDLANQLAKNINASIQDLTDDNESYTELDE
                     SVTFVANDFAQAVGYVVANDIKNCIYFLDIELSRESKAKNGVDLAEFIKKNDENAQIIF
                     VTAYDKYAPLTYRRRIGAIDYISKSMSSDKIIQRIEETLRNAFDNLSSRIKFGQRDFTY
                     KIGRRICKVAEDNILFIEHSTTQHKVHMVTENGEVEYKGNISQIDKENPFLVKVSQSYL
                     VNPRNINAIDMKEHTIIFDNDKMVTYSRAYKDVVKTLVNKFKDIEVK"
     CDS             5001..5252
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_65"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1e-18, bitscore:
                     60.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKLMVLNEEKLSYVIGGGNPKVAHCASQIGRSTAWGAVSGAATG
                     TAVGQAVGALGGALFGGSMGVIKGSAACVSYLTRHRHH"
     CDS             5286..5690
                     /locus_tag="ctg21_66"
                     /transl_table=11
                     /translation="MVKNKLVIKGITASIIYCLLGIIFDYIDSNLSIISIIENIGEGIV
                     FGLLMYWLLKSNNVRSISKHKINPLSSFVIGFFGSCLLLTLLLFLKIGYVSIDFYKSNF
                     YIISMIYLITGFIGGGALCFLSYVYRHKKE"
     CDS             5883..8045
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 314.5; E-value:
                     2.4e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_67"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1076.1,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 3e-45, bitscore:
                     146.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLQYKSIYVPQVDESDCGVACLAMILKKYHSRVSLAHLRHSART
                     NLEGTTALGLVKTAQTFNLKTEAVKADMSLFDPDTDIQYPFIVHVLKQGELLHYYVVLK
                     ATKNYLVIADPDPSVGLTKMSKEKFSQEWTGIALFMVPNDDFEPVKEKKRNLWSLFPYM
                     FKQKKLVTNIILAALLMTIISICSSYFLQGLIDTYIPNGTYQTLSILAIGLLIAYVFNS
                     IFSYGQNFLLNILGQRLSIDLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDAL
                     ASTVISLFLDLSIVIVMGIVLAIQNSTLFMITLLALPVYAVVILSFSKKFEKLNNDQME
                     SNAVLSSSVIEDIQGIETIKALNSEQTRYRKIDSQFVDYLKKSFRYSKTESLQSALKTF
                     IQLSLNVIILWVGAKVVMNGQMSIGQLMTFNALLSYFVDPLQSIINLQPTLQSANVAQN
                     RLNEVYMVKSEFQKDVQIRDAKQLVGDIEYHNVDYHYGYGVDVLKDVNLKIKQNDKLAI
                     VGMSGSGKSTMVKLLVDFFSPSKGKLTFNGFDSTKVDKHVLRSYVNYVPQTPYIFSGTI
                     KENLLLGSRPDITEEDVLKACQIAEIESEIEQLPLQFETKMDENAKILSGGQKQRLTIA
                     RALLSPAKVLIFDEATSGLDTITEKKVVDNLMKLKNKTIIFIAHRLAIAQRTNNIVVVD
                     HGQIVEQGSHDELMQKHGFYYNLVEN"
     CDS             8056..8646
                     /locus_tag="ctg21_68"
                     /transl_table=11
                     /translation="MNSKDYESTEFYSYKFKNFSTMIIIPMALLVFILIIGSFFAIRQS
                     TVTSTGIVEPQSTLDIANKNYHEGQIIKRNRSKWMVHLDDKKENIVHLLPIIKAKKSVN
                     IVTYFPGNKIGAIKKGQPLHFQLSNANGTTDRLVGEVKEVGIYPVNLHGNNVYEVICKA
                     KLDKDVKYGMEGNATIITGKSTYFEYFKDKILN"
     CDS             8812..10128
                     /locus_tag="ctg21_69"
                     /transl_table=11
                     /translation="MNKKNVSMLMLSPAILLMMNSTIVHADKGSTSHEISSKVVSKTKN
                     DDKNVPESEQETSSNNEIDQSQDKQEKEEQAIPEDQNDQSQNTNNQDPNDASEEDDEDE
                     VSVEDYENNVKDFHRVKMQEVKDLLAEKNNQEHLMYIGRPTCYYCRQFSPDLKDFNEIV
                     KGKLLYFNIDDEEGAHDYAFKVIGIPGTPTTMRFMNGKLISAWIGGEKTGQELHDFLYS
                     DTANKLVEQVVIKNQSNDTATQADNDVVASESDKTPEVTVEENNQAQSNNDVAITNFAE
                     NSVFENAKNVASSTADLTQVATGDQDDVAPKAETKNKTVKKPIKHKIVANKVKKQAKLH
                     KTNIIIPMSAKKREDVKENNQYDTVKVHGTSPNAIKDKQARITMLKELENDTSDTISTV
                     SLPSTGEKKNIWIQLMGMISVLVSVVLGISLRKKTKEEK"
     CDS             10129..10320
                     /locus_tag="ctg21_70"
                     /transl_table=11
                     /translation="MKQIIITENKVILSKILGGSSSIDDIGLNDTEHMLPLYSKKGSNH
                     KRDVYLENPRYQTHFKFM"
     CDS             10486..10680
                     /locus_tag="ctg21_71"
                     /transl_table=11
                     /translation="MNKFKDLNELELSNIAGGSNNIFWTRVGVGWAAEARCMIKPSLGN
                     WTTKAVSCGAKGLYAAVRG"
     CDS             10684..10839
                     /locus_tag="ctg21_72"
                     /transl_table=11
                     /translation="MKKKILESDLKNIKGGVAPIVYPIAGYVMKQMFEHSDQIIKGFKR
                     GWKKYK"
     CDS             10857..11072
                     /locus_tag="ctg21_73"
                     /transl_table=11
                     /translation="MKQIIKRGEEKTSKQWMIFVSLVSVLIAGGLYSWVNQAMLHTDSF
                     VLQTVITLLLAYVFVFAFLFVKGSKK"
     CDS             11269..11451
                     /locus_tag="ctg21_74"
                     /transl_table=11
                     /translation="MLPDKKRQIGSIIGMLIMMAILVFANLGGTWSVLRITLLAIGVTG
                     VIGSAIYRIIQILGG"
     CDS             11456..11995
                     /locus_tag="ctg21_75"
                     /transl_table=11
                     /translation="MKKFILNLLTVFAWIYQIFCVIGIIMGIVMIGVMPFGLKNPDFRA
                     GFESGRGIKGGSVDSYIGAIVVVLLSMIMMSVAAFLICRYARLIVKNIKQEVYFADSNL
                     NLLKKLLISVAGYTIISIVDFIMLMTHRAWFIKNANNVLYPSGVTTGLLFLAVLYVVYL
                     VFKYGMKVQEDADSII"
     CDS             12010..12219
                     /locus_tag="ctg21_76"
                     /transl_table=11
                     /translation="MIEVTLDFMLLKRKMSSKELAEKVGITPANLSILKTGKAHGVRFD
                     TLSKICEVLDCQPGDLLVYKKDEE"
     CDS             12352..12546
                     /locus_tag="ctg21_77"
                     /transl_table=11
                     /translation="MLYLIYIVLGLLIVLAVNYAVTAFLAVHDLLENREKDQLSFGDAF
                     KKYFAKNNNIPTKFSDLFN"
     CDS             12580..13002
                     /locus_tag="ctg21_78"
                     /transl_table=11
                     /translation="MNNEKFARENKRIIEGMVIGAIAGPIVFLVLMYFKNPGPLQIWQI
                     FVSIALGIVMGLTLGGVMSASLVLNKTVESKIPWRKKVLKLAPQVIGTGVVVAAAGVVI
                     TLVTNWGSVDIVKTIFSTDTLWQFFDGVLLGLITIR"
ORIGIN
        1 cttgggacta agtcaattag ctcccgcatt aaaattctat tgtgcgccca aatatgtaag
       61 tgaactactt gaatctggtc ttataaatgc acttgccatg ttcattctgg cattctttat
      121 ttttaaagca tggggattaa aatttgaatg gaatttgaaa tttatcaaaa ctaagaattt
      181 tcaatggtgg gcattagtgc tactgctcct tttctcagct tatttcccat tttttaatgt
      241 gtttttgggg atagcacaaa caccggtaca aatctttaac tgggatttta gtacttttga
      301 agtaacgttg actggatttc tttcagcagt agaagccgga atcatggaag aaacgcaacg
      361 ttgtttagat attgttgtac ttttatttgt ctttcgtaat tttaaaggaa aagtagtgtg
      421 ggctaccgta atttcttcac tattatttag cttggatcat ttgactaatt tgggttcaac
      481 gcaatttggc gttctttata atttgacaaa agttgaacag caaatgatct atacctttgg
      541 atttggcatg ttagctgcag ttttgtactt atatactggt aaattatggt taagcatgtt
      601 ggttcacttt ggcttagatt tcattgtctt tagtgaaacg ccattaactg tgtcgatatc
      661 tccatttttt gataattggg cttgtgcttt tattgtaatg gcagcatcat ccttggtagc
      721 catcttcatg ttattaggaa aaagatgtaa gtttatggat gataatgcag atagaattat
      781 gaaaatgtaa gtaagaaata tttggaagag tttaacaagt ttagagtaaa aaactgccaa
      841 atcagtataa tttaattttt aataaaaata ttaattatta tttaattgta gctgaattaa
      901 tgaaaggaag aaaattatga aaaaattgaa agtaatgaat aatggtgaat tagaaaaagt
      961 aatcggtggt tcattatatg aaatgaagaa ttcggtacca cgtttgttag gtccagatgg
     1021 aatggaaggt agtatgggtg gtagtactgg aggtattcaa tcgtttcgtc atttcccagg
     1081 attcggaaga taggaatagc atttagttaa actcaatgtg atgagaatta tcgcagtagg
     1141 tgagaataat gagaactaga attggacgga tgttttttcg ttataaaaga cataggctct
     1201 ctacctggtc agcgttaggg atgcttttat ttggtgtagc aaccttggcg ttatggattt
     1261 tcaatatgct actattcttg cagttcgtag gttatgctgc aacaatctac tacattattg
     1321 atattgaagc agggtatgcg gaagaaaaag taattggtaa ttcccaacat cgattaagta
     1381 agtctgatca gttctggctc ggattagctc aaacagtgac tgcaataatc ggtattgctg
     1441 aactggcagt gttgatctac tgtcaagtta ctaattatta tcacttcatg ttgagtgcag
     1501 tattccttac tgggttgtac tttacgtact ggacttgtct ctatggctta tccatttatc
     1561 aagtcaagag aagagttaac atagctgcta ggaaatggtt aattggtgaa attgtagctc
     1621 ttagcgttat ggcagctgtt atggtgagaa tttattttgt acaaaattgg gtattctttg
     1681 taattgtaat aggaattgcg attattgaat ggatcgtcag ttggcgtaat tattatgtaa
     1741 ttaaaaatgg cgatcggaat gcaatgggat actaatttgt ggaaacaacc aagttaaata
     1801 cttggttgtt ttttatatat ttgaaagaaa aatttagtaa ttaaacatct gatttagtca
     1861 aaatatgtgc taaattagta ttttttgttt taatagccga aatttaatta ttatttaagt
     1921 ataaattaat taaagaggtg aaaaatatgc aggaatggaa gaagactacc ttaagtgaca
     1981 atgagttgat tgacgtaatt ggtggttcag caaaaagcta tattcgtaga ttaggacctg
     2041 atggtggtta tggcggtcga gagagtaaat taatcgctat ggcagacatg attagacgac
     2101 gtatttaatt aaggtcaaaa atggctagta gtaagagatg aacctgaaat gtcgagccct
     2161 ggagttaaat atcaaaattc atacaaaatt tataaataaa tcaattagta ggtgatgaaa
     2221 atgaagctta gacaagaaca attgaataga aaagaattaa gtcaggttat tggtggccga
     2281 agagatatga tcttggtagc gcttcctcat gctgtaggtc cagatggtat gccaggtagc
     2341 ggtagaggtg gtggtgctca aatgagagcc attggcagta ttcctccatg gcgtccaaat
     2401 tggtggaagt agaattaagc aagatgccag atcggtacga aagtatgacc gaattggtat
     2461 ctttttttat tcgtttaaaa gtgcatgata tattaagagt gtaaataagt tgagtataaa
     2521 aatcatgaaa ggatgaaata tcatgaagaa gaaagttgtt aagaagactg ttttgaagga
     2581 aaaagaatta actaaggttg ttggcgggaa aaaagcacca atttctggtt atgtaggtag
     2641 aggactatgg gaaaacctaa gtaatatatt taaacatcac aagtaatcta atatggtctt
     2701 atacctatct atagttcaat ttttattgtc gagtgccata gatttatgga tgtttcttaa
     2761 aataactcgt ataaaattga atataaattt aaaactggga ctaacattag tagttattac
     2821 tataggatcg ataataagca taatattaga tgaatatggt ggcttacttt tagcaaatat
     2881 atctgagata ataggttttt atgtaatata taaaaagaaa aataacaaaa tacttgtagc
     2941 aggtgcaata gtttttgtat gtactttaga tctatttatt aatataattc tagcttttgc
     3001 ggcagttttt attaaagtag aaggttatat gagtataatc cttttatttg ttgaagcctg
     3061 gattgtaaaa aaatataata aaaatattta tagtacttta gtaggacaaa ataaaaaatc
     3121 atttttgtac atattatgtt atattttctt gtcaagtgaa atagtattgt tgattatttt
     3181 attaactaaa tcatataatg ctttttatac tgtagcaatg gtgttgtttg ctttgcaaat
     3241 tatattttca atcgttgcat atcatgaaat tgttagtatc cagcaagaac ttttaaataa
     3301 acaaaagcaa aaagagatcc ttgataatca acatcagctc gaagaatatg cctcttatct
     3361 tgaaaaaagt gaagatgatc tccgtgcctt cagacatgat tacaaaaata ttcttaattc
     3421 tttaaaggta agtgctcaag agggcaacgt taaagaagta attcagaaac tagataaata
     3481 cactgaaact aacttaaatt ctaaggctct actcaaatat aaagacgtaa atcacattta
     3541 cgttaaatca attaagagta ttattatttc caagttaaca gaattataca atttgaatat
     3601 tccatataac ttcgaatgtc gaagcaatat tcataattta ccagatcatg taaatgagct
     3661 tgatctagta cgtattattg gtattacctt tgataatgca attgaagaaa gcaaagcctt
     3721 ggttgctgag aaacatgata ttagaagcgc tgaagttcaa ataatggtct actctgatgg
     3781 tcctgatgag tttgagttcg aaatcagaaa taaaattcaa aataaaaaga tctcaactag
     3841 tcagattcaa caacgtggct ttactactaa gaaagatcat aagggactcg gattagctaa
     3901 tattaaagaa attgagggta aatatcctga tatgtctatt tcttatacaa ttcaagatgg
     3961 ctggtttgac ttctatatga caattgatac ggaagatggt gaagatgatg agtaaatttc
     4021 caattattgt gtgcgacgac gataaagact tggctaatca attggctaag aatattaatg
     4081 catctattca agatttaact gatgacaatg aaagttatac cgaattggat gaatctgtta
     4141 catttgttgc taatgatttt gctcaagcag taggatatgt cgttgcaaat gatattaaaa
     4201 actgtattta cttcttagat attgaattaa gccgtgagtc taaagctaag aatggcgtag
     4261 atctagctga attcattaag aagaatgatg agaatgccca gatcatcttt gtaacggcgt
     4321 acgacaagta cgctccgtta acatatcgcc gtcgtatcgg tgcaattgac tatataagta
     4381 agtccatgtc atctgataag attattcagc gtattgagga aactttgcgt aatgctttcg
     4441 ataatttatc tagcaggatt aagtttggtc aacgtgattt tacttataaa attggtcggc
     4501 gtatatgtaa agtagctgaa gacaatatac tttttattga acatagtact acgcagcata
     4561 aggtacatat ggttaccgaa aatggagagg tagaatacaa gggaaatatt agtcagattg
     4621 ataaagaaaa cccattttta gtaaaagtct ctcagtctta tttagtgaat ccaagaaata
     4681 ttaatgcgat tgatatgaaa gaacatacta ttatatttga taatgataag atggtaactt
     4741 attctagagc gtacaaagat gtggttaaaa cacttgtaaa taaatttaaa gatattgaag
     4801 ttaaataatt aaaaaactgg atttactcca gtttttttat tttagagata ataccaaatt
     4861 cgtatgagaa aacagtatta gtttataaaa tagctagatt ggttcatttt atttctaata
     4921 gctgttatgt tgatatcctt tatatgtaag ttgaaatgag ataaaaatct caaaaagtag
     4981 ttatttagga ggtaactaaa atggaaaagt taatggtatt aaatgaagaa aaattgagtt
     5041 atgtaattgg tggaggaaat cctaaagtag cacattgtgc tagtcaaatt ggtagatcaa
     5101 cggcttgggg tgcagttagc ggtgcagcta ctggaactgc agttggtcag gcagttggtg
     5161 cattgggtgg tgctcttttc ggtgggagta tgggcgttat caaaggctca gcagcatgtg
     5221 taagttattt aacgcgtcat agacatcatt aattgttttt gagtaaaatg tgaaaggcaa
     5281 aaaatatggt taaaaataaa ttggttatta aaggaataac agctagtatt atatattgtc
     5341 ttctcggaat aatatttgac tatattgata gtaatttatc aattatttca attattgaaa
     5401 atattggaga aggtatagta ttcggcttac ttatgtattg gctattaaaa agtaataatg
     5461 ttagatcaat atcaaagcat aaaattaatc ctttaagttc atttgttatt ggtttcttcg
     5521 gcagttgttt attactgact ttacttctat ttctaaaaat aggttatgta tcaattgatt
     5581 tttataagag taatttttat attattagta tgatttactt gattactgga tttattggtg
     5641 gtggagcttt atgttttctt tcctatgttt atagacataa gaaagagtaa catctttaag
     5701 ataatccata accttactag tttgtagata tttctaatct attttttgtc agtttactat
     5761 tttgaaatgt taaaaatact aaattagtta ttaaattaac caatttggta ttttttttat
     5821 ttgattcttc tgtcatgaaa taatgaacat atcttaataa aaacgtaaag gtagggagag
     5881 ctatgctact acaatataaa tcaatctatg taccacaagt agacgaatca gattgcggtg
     5941 ttgcctgttt ggctatgatt cttaagaaat atcattctag agtatcatta gcacatttgc
     6001 gccattcagc acgtactaat ttagaaggaa ctaccgccct tggcttagtc aaaacagcac
     6061 aaacatttaa tttgaaaact gaagcggtca aagctgatat gtccttgttt gatccagata
     6121 cggatatcca atatcctttt attgttcatg tcttaaaaca aggcgaatta ctccactatt
     6181 atgttgtact taaagcaact aaaaattatt tagtaattgc tgatccagat cctagcgttg
     6241 gtttaacgaa aatgtctaaa gaaaaattct ctcaagaatg gactggtatt gcccttttta
     6301 tggttcctaa tgacgatttt gagccagtta aggagaaaaa acgaaatctt tggtcgttgt
     6361 ttccatatat gttcaagcaa aagaaattag ttactaatat tattttggcc gcccttttaa
     6421 tgacaattat tagtatttgt agttcatatt tcttacaagg tttaattgat acttatattc
     6481 ctaatggcac atatcaaacc ttatcaattc tagccatcgg tttattgata gcatatgtct
     6541 ttaattccat cttttcttat ggtcaaaact ttttgttaaa tatcttagga caacgattaa
     6601 gtattgatct taatttacaa tatattcgcc atatttttga attaccaatg gaattttttg
     6661 tgactcgtag aacaggtgaa atcacttcta gattctctga tgctagtcga attattgacg
     6721 ccttagctag tacagttatt tcattatttc ttgacctttc aattgtaatt gtaatgggaa
     6781 ttgttttggc aattcaaaac tctactttat tcatgattac tttgttagca ctgccagtat
     6841 acgctgtagt gattcttagc ttttctaaga aatttgaaaa gctgaacaat gatcagatgg
     6901 aaagtaatgc agttttaagt tcttcagtaa ttgaggatat tcaagggatt gaaacgatca
     6961 aggctttaaa tagtgaacag acacggtacc gtaagattga tagtcaattt gtcgattatc
     7021 taaagaaatc ctttcgttac agtaaaactg aatctttgca gtcagctcta aagactttca
     7081 ttcaactgtc tctcaatgtg attatccttt gggtaggagc caaagttgta atgaacggtc
     7141 agatgagtat cggtcaatta atgacattta atgcattgct atcatatttt gtagatccac
     7201 ttcagagtat tattaatctt cagccaacct tacagtctgc taatgtagct caaaatcgat
     7261 tgaatgaagt atacatggtt aagagcgagt ttcagaaaga tgtccagatt agggatgcaa
     7321 agcaattagt aggagatatt gaataccata atgtcgatta tcattatggt tatggagttg
     7381 atgttttaaa ggacgttaat ttaaagatta agcagaatga taagttggcg atcgtaggaa
     7441 tgagtggctc aggcaagtca accatggtaa agcttttagt tgattttttc tctccaagca
     7501 aaggcaagtt aacttttaat ggatttgatt ctactaaagt agataagcat gtcttacggt
     7561 catacgtaaa ctatgttccc caaacaccat acatcttttc aggaacaatc aaagaaaatc
     7621 tgctcttagg tagtcgacca gatattacag aagaagatgt attgaaagct tgccagatag
     7681 cagagattga gtctgaaatc gagcaattac cattgcaatt tgaaactaag atggatgaaa
     7741 atgccaagat tttatccggt ggacaaaagc aaaggttaac tattgcacgt gcattattgt
     7801 caccagctaa ggttttgatt tttgatgaag ccacaagtgg acttgatacg attacggaga
     7861 aaaaagtagt agataactta atgaaattga agaataaaac tattattttt atcgcccatc
     7921 gtttagcaat tgcgcaaagg actaataata ttgtggttgt agaccatggt caaattgttg
     7981 agcaaggaag ccatgatgaa ttaatgcaaa aacatggatt ctattataac ttagttgaaa
     8041 attaggaggt aacttatgaa tagcaaagac tatgaaagta ctgaattcta ttcttataaa
     8101 tttaaaaatt tttcaactat gattatcatt cctatggcac ttttagtatt tatcttgata
     8161 attggctctt tctttgcaat cagacagagt acagttacat ctactggaat tgtagaacca
     8221 caaagtacac ttgatattgc caataaaaat tatcatgagg gacaaattat taaaagaaat
     8281 agaagtaaat ggatggttca tctagatgat aaaaaagaaa atatagtgca tttattacca
     8341 ataattaaag caaaaaaatc agttaatatc gttacatatt tccctggtaa taaaattggt
     8401 gcaattaaaa aaggacaacc cttacatttt caattatcta acgccaatgg aacaacagat
     8461 agactagttg gggaagtgaa agaagtagga atataccctg ttaacttaca cggaaacaat
     8521 gtttacgaag tgatttgtaa agctaaatta gataaagatg tgaagtatgg aatggaaggc
     8581 aatgcaacaa ttattacagg aaagagcaca tattttgaat attttaagga taaaattctt
     8641 aactaaaatt aaaaagagct gaaaagctct tttttaattg ggattaattc cgattgccat
     8701 gattaaagaa aactgatttg gttaaaaagt gtactgaata agtctaataa ccaaaaatat
     8761 agtgtacaat tgatatattt ttcttagtta taaaagatat ggggaatatc tatgaataag
     8821 aaaaatgtat caatgctaat gttaagtcca gcaatcttat taatgatgaa tagtactatt
     8881 gtgcatgcgg ataaaggtag tacttctcat gagattagta gtaaagtagt atctaaaaca
     8941 aaaaatgatg ataaaaatgt tcctgaatcc gagcaagaaa ctagtagtaa taacgaaatt
     9001 gatcaatctc aagataagca ggaaaaagaa gaacaagcaa ttcctgaaga tcaaaatgat
     9061 caatctcaga atacaaataa tcaagatcct aatgacgcaa gtgaagaaga tgatgaagat
     9121 gaagtatctg ttgaagatta tgaaaacaat gtaaaagatt ttcatagagt gaaaatgcaa
     9181 gaggtgaaag atcttctagc agagaaaaat aatcaagaac atcttatgta cattggtcgc
     9241 ccaacatgtt attactgccg acaattttca cctgatttaa aagatttcaa tgaaatcgtt
     9301 aaaggtaagc tgctttattt caatattgat gatgaagaag gagcacatga ttatgctttt
     9361 aaggttattg gtattccagg aacacctaca acgatgagat ttatgaatgg aaaattgata
     9421 agtgcttgga taggtggaga aaaaacagga caagagctac atgatttttt gtattctgac
     9481 acagctaata aattagtaga acaggttgta attaaaaatc aatcgaatga tacggctact
     9541 caagcagata atgatgtcgt tgcatctgag agcgataaaa cacctgaagt gactgtagag
     9601 gaaaataatc aagcgcagtc taataatgat gtcgctatta ctaacttcgc tgagaatagt
     9661 gtatttgaaa atgctaaaaa tgttgctagt tctactgcgg atttaactca agtagcgacg
     9721 ggcgatcaag atgatgtagc tcctaaagct gaaactaaaa ataaaactgt gaagaaacca
     9781 ataaaacata aaattgtagc caataaggtt aagaaacaag ctaaattgca taagacgaat
     9841 attattatac ctatgtccgc taaaaaacgt gaagatgtaa aagaaaataa tcaatatgat
     9901 acggtaaaag tacacggtac atctcctaat gcaattaagg acaaacaagc tagaattact
     9961 atgttgaagg aacttgagaa tgatacttca gatactattt ctactgtgtc tttgccgtct
    10021 actggtgaga agaaaaatat ctggattcaa ttaatgggaa tgattagtgt tctagttagt
    10081 gtagttttag gtatttcgtt aagaaagaaa actaaggagg aaaagtaaat gaagcaaatt
    10141 attattactg agaacaaagt gattttaagt aaaattttag gtggatcgag ttctatagat
    10201 gatattggtc tgaatgatac tgaacatatg ctacctttgt atagtaagaa agggagcaat
    10261 cataaaagag atgtttattt ggagaatcct agataccaaa cacattttaa atttatgtga
    10321 tgatcaatgt taaatacaaa acggcatcgc taaaatactg aaataaagat gaaagtagtt
    10381 tttagttata aagatagtca aattattcca gtttctattt aagaatagaa attttagtaa
    10441 tatgaatttg tacttgaata agttttttat taggaggtaa ttgagatgaa taaatttaaa
    10501 gatttgaatg aattagaatt aagtaatatt gctgggggaa gtaacaacat tttttggaca
    10561 agagtcggag ttggttgggc tgcagaagcg agatgcatga tcaaacccag tctcggtaat
    10621 tggactacga aagcagtaag ctgtggagca aaaggattat atgcagcggt gaggggataa
    10681 ctaatgaaaa agaaaatatt agaatcagat ttaaaaaata taaagggtgg ggtggctcct
    10741 atagtatatc cgatagcagg atatgtaatg aaacagatgt ttgaacactc agatcaaata
    10801 ataaagggat ttaaacgagg atggaaaaaa tataaatagc aagaggatgc ccaaaaatga
    10861 aacaaataat aaaacgtgga gaagaaaaga catcaaaaca atggatgatc tttgtgtctt
    10921 tagttagcgt gctaattgct ggtggattat atagttgggt gaatcaagca atgttacata
    10981 cagatagttt cgttctacaa actgtcatta ctttgctgct ggcttacgtt ttcgtatttg
    11041 ctttcctatt tgttaagggc agtaaaaagt aggattaaag gctgtagaca aagctgagag
    11101 aaatgaataa attaaaagca tcaagttagt ttagcgacta atttggtgct ttttattatc
    11161 ctaaaaaaat attttatttc tgtattgcaa ttataaatta tcgtaataca ataattatca
    11221 aaaggaataa gaaagagata gatagtttca tggaagagag ggatagatat gcttccagat
    11281 aagaaaagac aaataggctc aattattgga atgctgataa tgatggcaat cttagtgttt
    11341 gctaacttag gtggaacatg gagtgttctt agaattacat tattagcaat tggagtaacg
    11401 ggtgtaattg gcagtgctat atacagaatc attcagattt tgggaggata gaaaaatgaa
    11461 aaagtttatt ttgaatttgt tgacagtttt tgcttggatt taccaaatat tttgcgtaat
    11521 aggaataatt atgggaattg ttatgatagg tgttatgcca ttcggcttaa aaaatccaga
    11581 ttttcgtgct ggttttgaaa gtggtagggg tataaaaggt ggatcagttg atagctatat
    11641 tggtgcaata gtggttgtgt tgctgtcaat gatcatgatg agcgttgcag cttttttgat
    11701 ctgtcgatat gccagattaa ttgttaagaa tatcaagcaa gaagtttact ttgctgatag
    11761 taatttgaat ttactcaaaa aattattaat ttcagttgct ggatatacca tcatttcaat
    11821 agtagatttc attatgctaa tgactcaccg cgcttggttc attaaaaatg cgaataatgt
    11881 actttatcca agcggtgtaa caactggatt actttttcta gcagtactat atgtagtcta
    11941 cttggtattc aagtacggaa tgaaagttca ggaggatgca gactcgatta tttagaaagg
    12001 ttgatataga tgattgaagt gacactagat tttatgctct tgaagcgaaa gatgtcttca
    12061 aaggagctag cagaaaaggt tggcatcacg ccggctaatt tgtcaattct gaagacagga
    12121 aaggcacatg gcgttcgttt tgacacattg agcaagatct gtgaagtctt ggattgtcaa
    12181 ccaggggatt tattagttta taaaaaagat gaagaataaa atgcaaaatc agtccgataa
    12241 atgacagaat tggacggttt tggcaattat gtaaatgatg gggatatgat taatttaaaa
    12301 agataagaga ttatttcttg ggagataatc gctaaattgg aggaaagaaa aatgctgtac
    12361 ttaatttaca ttgtgcttgg cttgctaatc gttttagccg ttaattacgc tgttacagca
    12421 ttcttggctg ttcacgattt acttgaaaat agagaaaaag atcaattaag ctttggggat
    12481 gcattcaaga aatacttcgc caagaacaac aatattccga ctaagttttc ggatttgttt
    12541 aattagaaat gaaaaacaaa tttccttgag gtaagaaaaa tgaataacga aaaatttgct
    12601 cgtgaaaaca agagaattat tgagggaatg gtaatcggag caattgctgg accaatagta
    12661 tttcttgtgt tgatgtattt taaaaatccc ggtccacttc aaatttggca gatttttgtt
    12721 tctattgcac ttggaatcgt tatgggcttg acattaggtg gtgttatgtc cgcaagttta
    12781 gtccttaata agacagtaga gtcaaaaatt ccatggcgta agaaagtgtt gaagctggcc
    12841 cctcaagtta ttggtacagg agtagtggtt gctgcagctg gtgtagtgat tactttagta
    12901 accaattggg gatcagttga tattgtaaaa acaatttttt caaccgatac tttatggcag
    12961 ttctttgacg gtgtacttct aggtctaata accattagat aaaaagtgga gggatagatc
    13021 atgttggaaa aagctaaaag acaat
//
