LOCUS       c00022_JAAPAR0..       13044 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAAPAR010000007.1 Lactobacillus acidophilus strain BCRC 17486
            Scaffold7_1, whole genome shotgun sequence.
ACCESSION   JAAPAR010000007
VERSION     JAAPAR010000007
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-19 19:50:00
            Original ID  :: JAAPAR010000007.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 54392
            Orig. end    :: 67436
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13044
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[59392:62436]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8044
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..13044
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13044
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(44..466)
                     /locus_tag="ctg22_60"
                     /transl_table=11
                     /translation="MNNEKFARENKRIIEGMVIGAIAGPIVFLVLMYFKNPGPLQIWQI
                     FVSIALGIVMGLTLGGVMSASLVLNKTVESKIPWRKKVLKLAPQVIGTGVVVAAAGVVI
                     TLVTNWGSVDIVKTIFSTDTLWQFFDGVLLGLITIR"
     CDS             complement(500..694)
                     /locus_tag="ctg22_61"
                     /transl_table=11
                     /translation="MLYLIYIVLGLLIVLAVNYAVTAFLAVHDLLENREKDQLSFGDAF
                     KKYFAKNNNIPTKFSDLFN"
     CDS             complement(827..1036)
                     /locus_tag="ctg22_62"
                     /transl_table=11
                     /translation="MIEVTLDFMLLKRKMSSKELAEKVGITPANLSILKTGKAHGVRFD
                     TLSKICEVLDCQPGDLLVYKKDEE"
     CDS             complement(1051..1590)
                     /locus_tag="ctg22_63"
                     /transl_table=11
                     /translation="MKKFILNLLTVFAWIYQIFCVIGIIMGIVMIGVMPFGLKNPDFRA
                     GFESGRGIKGGSVDSYIGAIVVVLLSMIMMSVAAFLICRYARLIVKNIKQEVYFADSNL
                     NLLKKLLISVAGYTIISIVDFIMLMTHRAWFIKNANNVLYPSGVTTGLLFLAVLYVVYL
                     VFKYGMKVQEDADSII"
     CDS             complement(1595..1777)
                     /locus_tag="ctg22_64"
                     /transl_table=11
                     /translation="MLPDKKRQIGSIIGMLIMMAILVFANLGGTWSVLRITLLAIGVTG
                     VIGSAIYRIIQILGG"
     CDS             complement(1974..2189)
                     /locus_tag="ctg22_65"
                     /transl_table=11
                     /translation="MKQIIKRGEEKTSKQWMIFVSLVSVLIAGGLYSWVNQAMLHTDSF
                     VLQTVITLLLAYVFVFAFLFVKGSKK"
     CDS             complement(2207..2362)
                     /locus_tag="ctg22_66"
                     /transl_table=11
                     /translation="MKKKILESDLKNIKGGVAPIVYPIAGYVMKQMFEHSDQIIKGFKR
                     GWKKYK"
     CDS             complement(2726..2917)
                     /locus_tag="ctg22_67"
                     /transl_table=11
                     /translation="MKQIIITENKVILSKILGGSSSIDDIGLNDTEHMLPLYSKKGSNH
                     KRDVYLENPRYQTHFKFM"
     CDS             complement(2918..4234)
                     /locus_tag="ctg22_68"
                     /transl_table=11
                     /translation="MNKKNVSMLMLSPAILLMMNSTIVHADKGSTSHEISSKVVSKTKN
                     DDKNVPESEQETSSNNEIDQSQDKQEKEEQAIPEDQNDQSQNTNNQDPNDASEEDDEDE
                     VSVEDYENNVKDFHRVKMQEVKDLLAEKNNQEHLMYIGRPTCYYCRQFSPDLKDFNEIV
                     KGKLLYFNIDDEEGAHDYAFKVIGIPGTPTTMRFMNGKLISAWIGGEKTGQELHDFLYS
                     DTANKLVEQVVIKNQSNDTATQADNDVVASESDKTPEVTVEENNQAQSNNDVAITNFAE
                     NSVFENAKNVASSTADLTQVATGDQDDVAPKAETKNKTVKKPIKHKIVANKVKKQAKLH
                     KTNIIIPMSAKKREDVKENNQYDTVKVHGTSPNAIKDKQARITMLKELENDTSDTISTV
                     SLPSTGEKKNIWIQLMGMISVLVSVVLGISLRKKTKEEK"
     CDS             complement(4400..4990)
                     /locus_tag="ctg22_69"
                     /transl_table=11
                     /translation="MNSKDYESTEFYSYKFKNFSTMIIIPMALLVFILIIGSFFAIRQS
                     TVTSTGIVEPQSTLDIANKNYHEGQIIKRNRSKWMVHLDDKKENIVHLLPIIKAKKSVN
                     IVTYFPGNKIGAIKKGQPLHFQLSNANGTTDRLVGEVKEVGIYPVNLHGNNVYEVICKA
                     KLDKDVKYGMEGNATIITGKSTYFEYFKDKILN"
     CDS             complement(5001..7163)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 314; E-value: 3.4e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_70"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1075.9,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 3e-45, bitscore:
                     146.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLQYKSIYVPQVDESDCGVACLAMILKKYHSRVSLAHLRHSART
                     NLEGTTALGLVKTAQTFNLKTEAVKADMSLFDPDTDIQYPFIVHVLKQGELLHYYVVLK
                     ATKNYLVIADPDPSVGLTKMSKEKFSQEWTGIALFMVPNDDFEPVKEKKRNLWSLFPYM
                     FKQKKLVTNIILAALLMTIISICSSYFLQGLIDTYIPNGTYQTLSILAIGLLIAYVFNS
                     IFSYGQNFLLNILGQRLSIDLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDAL
                     ASTVISLFLDLSIVIVMGIVLAIQNSTLFMITLLALPVYAVVILSFSKKFEKLNNDQME
                     SNAVLSSSVIEDIQGIETIKALNSEQTRYRKIDSQFVDYLKKSFRYSKTESLQSALKTF
                     IQLSLNVIILWVGAKVVMNGQMSIGQLMTFNALLSYFVDPLQSIINLQPTLQSANVAQN
                     RLNEVYMVKSEFQKDVQIRDAKQLVGDIEYHNVDYHYGYGVDVLKDVNLKIKQNDKLAI
                     VGMSGSGKSTMVKLLVDFFSPSKGKLTFNGFDSTKVDKHVLRSYVNYVPQTPYIFSGTI
                     KENLLLGSRPDITEEDVLKACHIAEIESEIEQLPLQFETKMDENAKILSGGQKQRLTIA
                     RALLSPAKVLIFDEATSGLDTITEKKVVDNLMKLKNKTIIFIAHRLAIAQRTNNIVVVD
                     HGQIVEQGSHDELMQKHGFYYNLVEN"
     CDS             complement(7355..7759)
                     /locus_tag="ctg22_71"
                     /transl_table=11
                     /translation="MVKNKLVIKGITASIIYCLLGIIFDYIDSNLSIISIIENIGEGIV
                     FGLLMYWLLKSNNVRSISKHKINPLSSFVIGFFGSCLLLTLLLFLKIGYVSIDFYKSNF
                     YIISMIYLITGFIGGGALCFLSYVYRHKKE"
     CDS             complement(7793..8044)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_72"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1e-18, bitscore:
                     60.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKLMVLNEEKLSYVIGGGNPKVAHCASQIGRSTAWGAVSGAATG
                     TAVGQAVGALGGALFGGSMGVIKGSAACVSYLTRHRHH"
     CDS             complement(8237..9046)
                     /locus_tag="ctg22_73"
                     /transl_table=11
                     /translation="VKMMSKFPIIVCDDDKDLANQLAKNINASIQDLTDDNESYTELDE
                     SVTFVANDFAQAVGYVVANDIKNCIYFLDIELSRESKAKNGVDLAEFIKKNDENAQIIF
                     VTAYDKYAPLTYRRRIGAIDYISKSMSSDKIIQRIEETLRNAFDNLSSRIKFGQRDFTY
                     KIGRRICKVAEDNILFIEHSTTQHKVHMVTENGEVEYKGNISQIDKENPFLVKVSQSYL
                     VNPRNINAIDMKEHTIIFDNDKMVTYSRAYKDVVKTLVNKFKDIEVK"
     CDS             complement(9030..10352)
                     /locus_tag="ctg22_74"
                     /transl_table=11
                     /translation="MVLYLSIVQFLLSSAIDLWMFLKITRIKLNINLKLGLTLVVITIG
                     SIISIILDEYGGLLLANISEIIGFYVIYKKKNNKILVAGAIVFVCTLDLFINIILAFAA
                     VFIKVEGYMSIILLFVEAWIVKKYNKNIYSTLVGQNKKSFLYILCYIFLSSEIVLLIIL
                     LTKSYNAFYTVAMVLFALQIIFSIVAYHEIVSIQQELLNKQKQKEILDNQHQLEEYASY
                     LEKSEDDLRAFRHDYKNILNSLKVSAQEGNVKEVIQKLDKYTETNLNSKALLKYKDVNH
                     IYVKSIKSIIISKLTELYNLNIPYNFECRSNIHNLPDHVNELDLVRIIGITFDNAIEES
                     KALVAEKHDIRSAEVQIMVYSDGPDEFEFEIRNKIQNKKISTSQIQQRGFTTKKDHKGL
                     GLANIKEIEGKYPDMSISYTIQDGWFDFYMTIDTEDGEDDE"
     CDS             complement(10359..10502)
                     /locus_tag="ctg22_75"
                     /transl_table=11
                     /translation="MKKKVVKKTVLKEKELTKVVGGKKAPISGYVGRGLWENLSNIFKH
                     HK"
     CDS             complement(10633..10824)
                     /locus_tag="ctg22_76"
                     /transl_table=11
                     /translation="MKLRQEQLNRKELSQVIGGRRDMILVALPHAVGPDGMPGSGRGGG
                     AQMRAIGSIPPWRPNWWK"
     CDS             complement(10937..11098)
                     /locus_tag="ctg22_77"
                     /transl_table=11
                     /translation="MQEWKKTTLSDNELIDVIGGSAKSYIRRLGPDGGYGGRESKLIAM
                     ADMIRRRI"
     CDS             complement(11270..11896)
                     /locus_tag="ctg22_78"
                     /transl_table=11
                     /translation="MRTRIGRMFFRYKRHRLSTWSALGMLLFGVATLALWIFNMLLFLQ
                     FVGYAATIYYIIDIEAGYAEEKVIGNSQHRLSKSDQFWLGLAQTVTAIIGIAELAVLIY
                     CQVTNYYHFMLSAVFLTGLYFTYWTCLYGLSIYQVKRRVNIAARKWLIGEIVALSVMAA
                     VMVRIYFVQNWVFFVIVIGIAIIEWIVSWRNYYVIKNGDRNAMGY"
     CDS             complement(11952..12128)
                     /locus_tag="ctg22_79"
                     /transl_table=11
                     /translation="MKKLKVMNNGELEKVIGGSLYEMKNSVPRLLGPDGMEGSMGGSTG
                     GIQSFRHFPGFGR"
ORIGIN
        1 attgtctttt agctttttcc aacatgatct atccctccac tttttatcta atggttatta
       61 gacctagaag tacaccgtca aagaactgcc ataaagtatc ggttgaaaaa attgttttta
      121 caatatcaac tgatccccaa ttggttacta aagtaatcac tacaccagct gcagcaacca
      181 ctactcctgt accaataact tgaggggcca gcttcaacac tttcttacgc catggaattt
      241 ttgactctac tgtcttatta aggactaaac ttgcggacat aacaccacct aatgtcaagc
      301 ccataacgat tccaagtgca atagaaacaa aaatctgcca aatttgaagt ggaccgggat
      361 ttttaaaata catcaacaca agaaatacta ttggtccagc aattgctccg attaccattc
      421 cctcaataat tctcttgttt tcacgagcaa atttttcgtt attcattttt cttacctcaa
      481 ggaaatttgt ttttcatttc taattaaaca aatccgaaaa cttagtcgga atattgttgt
      541 tcttggcgaa gtatttcttg aatgcatccc caaagcttaa ttgatctttt tctctatttt
      601 caagtaaatc gtgaacagcc aagaatgctg taacagcgta attaacggct aaaacgatta
      661 gcaagccaag cacaatgtaa attaagtaca gcatttttct ttcctccaat ttagcgatta
      721 tctcccaaga aataatctct tatcttttta aattaatcat atccccatca tttacataat
      781 tgccaaaacc gtccaattct gtcatttatc ggactgattt tgcattttat tcttcatctt
      841 ttttataaac taataaatcc cctggttgac aatccaagac ttcacagatc ttgctcaatg
      901 tgtcaaaacg aacgccatgt gcctttcctg tcttcagaat tgacaaatta gccggcgtga
      961 tgccaacctt ttctgctagc tcctttgaag acatctttcg cttcaagagc ataaaatcta
     1021 gtgtcacttc aatcatctat atcaaccttt ctaaataatc gagtctgcat cctcctgaac
     1081 tttcattccg tacttgaata ccaagtagac tacatatagt actgctagaa aaagtaatcc
     1141 agttgttaca ccgcttggat aaagtacatt attcgcattt ttaatgaacc aagcgcggtg
     1201 agtcattagc ataatgaaat ctactattga aatgatggta tatccagcaa ctgaaattaa
     1261 taattttttg agtaaattca aattactgtc agcaaagtaa acttcttgct tgatattctt
     1321 aacaattaat ctggcatatc gacagatcaa aaaagctgca acgctcatca tgatcattga
     1381 cagcaacaca accactattg caccaatata gctatcaact gatccacctt ttatacccct
     1441 accactttca aaaccagcac gaaaatctgg attttttaag ccgaatggca taacacctat
     1501 cataacaatt cccataatta ttcctattac gcaaaatatt tggtaaatcc aagcaaaaac
     1561 tgtcaacaaa ttcaaaataa actttttcat ttttctatcc tcccaaaatc tgaatgattc
     1621 tgtatatagc actgccaatt acacccgtta ctccaattgc taataatgta attctaagaa
     1681 cactccatgt tccacctaag ttagcaaaca ctaagattgc catcattatc agcattccaa
     1741 taattgagcc tatttgtctt ttcttatctg gaagcatatc tatccctctc ttccatgaaa
     1801 ctatctatct ctttcttatt ccttttgata attattgtat tacgataatt tataattgca
     1861 atacagaaat aaaatatttt tttaggataa taaaaagcac caaattagtc gctaaactaa
     1921 cttgatgctt ttaatttatt catttctctc agctttgtct acagccttta atcctacttt
     1981 ttactgccct taacaaatag gaaagcaaat acgaaaacgt aagccagcag caaagtaatg
     2041 acagtttgta gaacgaaact atctgtatgt aacattgctt gattcaccca actatataat
     2101 ccaccagcaa ttagcacgct aactaaagac acaaagatca tccattgttt tgatgtcttt
     2161 tcttctccac gttttattat ttgtttcatt tttgggcatc ctcttgctat ttatattttt
     2221 tccatcctcg tttaaatccc tttattattt gatctgagtg ttcaaacatc tgtttcatta
     2281 catatcctgc tatcggatat actataggag ccaccccacc ctttatattt tttaaatctg
     2341 attctaatat tttctttttc attagttatc ccctcaccgc tgcatataat ccttttgctc
     2401 cacagcttac tgctttcgta gtccaattac cgagactggg tttgatcatg catctcgctt
     2461 ctgcagccca accaactccg actcttgtcc aaaaaatgtt gttacttccc ccagcaatat
     2521 tacttaattc taattcattc aaatctttaa atttattcat ctcaattacc tcctaataaa
     2581 aaacttattc aagtacaaat tcatattact aaaatttcta ttcttaaata gaaactggaa
     2641 taatttgact atctttataa ctaaaaacta ctttcatctt tatttcagta ttttagcgat
     2701 gccgttttgt atttaacatt gatcatcaca taaatttaaa atgtgtttgg tatctaggat
     2761 tctccaaata aacatctctt ttatgattgc tccctttctt actatacaaa ggtagcatat
     2821 gttcagtatc attcagacca atatcatcta tagaactcga tccacctaaa attttactta
     2881 aaatcacttt gttctcagta ataataattt gcttcattta cttttcctcc ttagttttct
     2941 ttcttaacga aatacctaaa actacactaa ctagaacact aatcattccc attaattgaa
     3001 tccagatatt tttcttctca ccagtagacg gcaaagacac agtagaaata gtatctgaag
     3061 tatcattctc aagttccttc aacatagtaa ttctagcttg tttgtcctta attgcattag
     3121 gagatgtacc gtgtactttt accgtatcat attgattatt ttcttttaca tcttcacgtt
     3181 ttttagcgga cataggtata ataatattcg tcttatgcaa tttagcttgt ttcttaacct
     3241 tattggctac aattttatgt tttattggtt tcttcacagt tttattttta gtttcagctt
     3301 taggagctac atcatcttga tcgcccgtcg ctacttgagt taaatccgca gtagaactag
     3361 caacattttt agcattttca aatacactat tctcagcgaa gttagtaata gcgacatcat
     3421 tattagactg cgcttgatta ttttcctcta cagtaacttc aggtgtttta tcgctctcag
     3481 atgcaacgac atcattatct gcttgagtag ccgtatcatt cgattgattt ttaattacaa
     3541 cctgttctac taatttatta gctgtgtcag aatacaaaaa atcatgtagc tcttgtcctg
     3601 ttttttctcc acctatccaa gcacttatca attttccatt cataaatctc atcgttgtag
     3661 gtgttcctgg aataccaata accttaaaag cataatcatg tgctccttct tcatcatcaa
     3721 tattgaaata aagcagctta cctttaacga tttcattgaa atcttttaaa tcaggtgaaa
     3781 attgtcggca gtaataacat gttgggcgac caatgtacat aagatgttct tgattatttt
     3841 tctctgctag aagatctttc acctcttgca ttttcactct atgaaaatct tttacattgt
     3901 tttcataatc ttcaacagat acttcatctt catcatcttc ttcacttgcg tcattaggat
     3961 cttgattatt tgtattctga gattgatcat tttgatcttc aggaattgct tgttcttctt
     4021 tttcctgctt atcttgagat tgatcaattt cgttattact actagtttct tgctcggatt
     4081 caggaacatt tttatcatca ttttttgttt tagatactac tttactacta atctcatgag
     4141 aagtactacc tttatccgca tgcacaatag tactattcat cattaataag attgctggac
     4201 ttaacattag cattgataca tttttcttat tcatagatat tccccatatc ttttataact
     4261 aagaaaaata tatcaattgt acactatatt tttggttatt agacttattc agtacacttt
     4321 ttaaccaaat cagttttctt taatcatggc aatcggaatt aatcccaatt aaaaaagagc
     4381 ttttcagctc tttttaattt tagttaagaa ttttatcctt aaaatattca aaatatgtgc
     4441 tctttcctgt aataattgtt gcattgcctt ccattccata cttcacatct ttatctaatt
     4501 tagctttaca aatcacttcg taaacattgt ttccgtgtaa gttaacaggg tatattccta
     4561 cttctttcac ttccccaact agtctatctg ttgttccatt ggcgttagat aattgaaaat
     4621 gtaagggttg tcctttttta attgcaccaa ttttattacc agggaaatat gtaacgatat
     4681 taactgattt ttttgcttta attattggta ataaatgcac tatattttct tttttatcat
     4741 ctagatgaac catccattta cttctatttc ttttaataat ttgtccctca tgataatttt
     4801 tattggcaat atcaagtgta ctttgtggtt ctacaattcc agtagatgta actgtactct
     4861 gtctgattgc aaagaaagag ccaattatca agataaatac taaaagtgcc ataggaatga
     4921 taatcatagt tgaaaaattt ttaaatttat aagaatagaa ttcagtactt tcatagtctt
     4981 tgctattcat aagttacctc ctaattttca actaagttat aatagaatcc atgtttttgc
     5041 attaattcat catggcttcc ttgctcaaca atttgaccat ggtctacaac cacaatatta
     5101 ttagtccttt gcgcaattgc taaacgatgg gcgataaaaa taatagtttt attcttcaat
     5161 ttcattaagt tatctactac ttttttctcc gtaatcgtat caagtccact tgtggcttca
     5221 tcaaaaatca aaaccttagc tggtgacaat aatgcacgtg caatagttaa cctttgcttt
     5281 tgtccaccgg ataaaatctt ggcattttca tccatcttag tttcaaattg caatggtaat
     5341 tgctcgattt cagactcaat ctctgctata tggcaagctt tcaatacatc ttcttctgta
     5401 atatctggtc gactacctaa gagcagattt tctttgattg ttcctgaaaa gatgtatggt
     5461 gtttggggaa catagtttac gtatgaccgt aagacatgct tatctacttt agtagaatca
     5521 aatccattaa aagttaactt gcctttgctt ggagagaaaa aatcaactaa aagctttacc
     5581 atggttgact tgcctgagcc actcattcct acgatcgcca acttatcatt ctgcttaatc
     5641 tttaaattaa cgtcctttaa aacatcaact ccataaccat aatgataatc gacattatgg
     5701 tattcaatat ctcctactaa ttgctttgca tccctaatct ggacatcttt ctgaaactcg
     5761 ctcttaacca tgtatacttc attcaatcga ttttgagcta cattagcaga ctgtaaggtt
     5821 ggctgaagat taataatact ctgaagtgga tctacaaaat atgatagcaa tgcattaaat
     5881 gtcattaatt gaccgatact catctgaccg ttcattacaa ctttggctcc tacccaaagg
     5941 ataatcacat tgagagacag ttgaatgaaa gtctttagag ctgactgcaa agattcagtt
     6001 ttactgtaac gaaaggattt ctttagataa tcgacaaatt gactatcaat cttacggtac
     6061 cgtgtctgtt cactatttaa agccttgatc gtttcaatcc cttgaatatc ctcaattact
     6121 gaagaactta aaactgcatt actttccatc tgatcattgt tcagcttttc aaatttctta
     6181 gaaaagctaa gaatcactac agcgtatact ggcagtgcta acaaagtaat catgaataaa
     6241 gtagagtttt gaattgccaa aacaattccc attacaatta caattgaaag gtcaagaaat
     6301 aatgaaataa ctgtactagc taaggcgtca ataattcgac tagcatcaga gaatctagaa
     6361 gtgatttcac ctgttctacg agtcacaaaa aattccattg gtaattcaaa aatatggcga
     6421 atatattgta aattaagatc aatacttaat cgttgtccta agatatttaa caaaaagttt
     6481 tgaccataag aaaagatgga attaaagaca tatgctatca ataaaccgat ggctagaatt
     6541 gataaggttt gatatgtgcc attaggaata taagtatcaa ttaaaccttg taagaaatat
     6601 gaactacaaa tactaataat tgtcattaaa agggcggcca aaataatatt agtaactaat
     6661 ttcttttgct tgaacatata tggaaacaac gaccaaagat ttcgtttttt ctccttaact
     6721 ggctcaaaat cgtcattagg aaccataaaa agggcaatac cagtccattc ttgagagaat
     6781 ttttctttag acattttcgt taaaccaacg ctaggatctg gatcagcaat tactaaataa
     6841 tttttagttg ctttaagtac aacataatag tggagtaatt cgccttgttt taagacatga
     6901 acaataaaag gatattggat atccgtatct ggatcaaaca aggacatatc agctttgacc
     6961 gcttcagttt tcaaattaaa tgtttgtgct gttttgacta agccaagggc ggtagttcct
     7021 tctaaattag tacgtgctga atggcgcaaa tgtgctaatg atactctaga atgatatttc
     7081 ttaagaatca tagccaaaca ggcaacaccg caatctgatt cgtctacttg tggtacatag
     7141 attgatttat attgtagtag catagctctc cctaccttta cgtttttatt aagatatgtt
     7201 cattatttca tgacagaaga atcaaataaa aaaaatacca aattggttaa tttaataact
     7261 aatttagtat ttttaacatt tcaaaatagt aaactgaaaa aaatagatta gaaatatcta
     7321 caaactagta aggttatgga ttatcttaaa gatgttactc tttcttatgt ctataaacat
     7381 aggaaagaaa acataaagct ccaccaccaa taaatccagt aatcaagtaa atcatactaa
     7441 taatataaaa attactctta taaaaatcaa ttgatacata acctattttt agaaatagaa
     7501 gtaaagtcag taataaacaa ctgccgaaga aaccaataac aaatgaactt aaaggattaa
     7561 ttttatgctt tgatattgat ctaacattat tactttttaa tagccaatac ataagtaagc
     7621 cgaatactat accttctcca atattttcaa taattgaaat aattgataaa ttactatcaa
     7681 tatagtcaaa tattattccg agaagacaat atataatact agctgttatt cctttaataa
     7741 ccaatttatt tttaaccata ttttttgcct ttcacatttt actcaaaaac aattaatgat
     7801 gtctatgacg cgttaaataa cttacacatg ctgctgagcc tttgataacg cccatactcc
     7861 caccgaaaag agcaccaccc aatgcaccaa ctgcctgacc aactgcagtt ccagtagctg
     7921 caccgctaac tgcaccccaa gccgttgatc taccaatttg actagcacaa tgtgctactt
     7981 taggatttcc tccaccaatt acataactca atttttcttc atttaatacc attaactttt
     8041 ccattttagt tacctcctaa ataactactt tttgagattt ttatctcatt tcaacttaca
     8101 tataaaggat atcaacataa cagctattag aaataaaatg aaccaatcta gctattttat
     8161 aaactaatac tgttttctca tacgaatttg gtattatctc taaaataaaa aaactggagt
     8221 aaatccagtt ttttaattat ttaacttcaa tatctttaaa tttatttaca agtgttttaa
     8281 ccacatcttt gtacgctcta gaataagtta ccatcttatc attatcaaat ataatagtat
     8341 gttctttcat atcaatcgca ttaatatttc ttggattcac taaataagac tgagagactt
     8401 ttactaaaaa tgggttttct ttatcaatct gactaatatt tcccttgtat tctacctctc
     8461 cattttcggt aaccatatgt accttatgct gcgtagtact atgttcaata aaaagtatat
     8521 tgtcttcagc tactttacat atacgccgac caattttata agtaaaatca cgttgaccaa
     8581 acttaatcct gctagataaa ttatcgaaag cattacgcaa agtttcctca atacgctgaa
     8641 taatcttatc agatgacatg gacttactta tatagtcaat tgcaccgata cgacggcgat
     8701 atgttaacgg agcgtacttg tcgtacgccg ttacaaagat gatctgggca ttctcatcat
     8761 tcttcttaat gaattcagct agatctacgc cattcttagc tttagactca cggcttaatt
     8821 caatatctaa gaagtaaata cagtttttaa tatcatttgc aacgacatat cctactgctt
     8881 gagcaaaatc attagcaaca aatgtaacag attcatccaa ttcggtataa ctttcattgt
     8941 catcagttaa atcttgaata gatgcattaa tattcttagc caattgatta gccaagtctt
     9001 tatcgtcgtc gcacacaata attggaaatt tactcatcat cttcaccatc ttccgtatca
     9061 attgtcatat agaagtcaaa ccagccatct tgaattgtat aagaaataga catatcagga
     9121 tatttaccct caatttcttt aatattagct aatccgagtc ccttatgatc tttcttagta
     9181 gtaaagccac gttgttgaat ctgactagtt gagatctttt tattttgaat tttatttctg
     9241 atttcgaact caaactcatc aggaccatca gagtagacca ttatttgaac ttcagcgctt
     9301 ctaatatcat gtttctcagc aaccaaggct ttgctttctt caattgcatt atcaaaggta
     9361 ataccaataa tacgtactag atcaagctca tttacatgat ctggtaaatt atgaatattg
     9421 cttcgacatt cgaagttata tggaatattc aaattgtata attctgttaa cttggaaata
     9481 ataatactct taattgattt aacgtaaatg tgatttacgt ctttatattt gagtagagcc
     9541 ttagaattta agttagtttc agtgtattta tctagtttct gaattacttc tttaacgttg
     9601 ccctcttgag cacttacctt taaagaatta agaatatttt tgtaatcatg tctgaaggca
     9661 cggagatcat cttcactttt ttcaagataa gaggcatatt cttcgagctg atgttgatta
     9721 tcaaggatct ctttttgctt ttgtttattt aaaagttctt gctggatact aacaatttca
     9781 tgatatgcaa cgattgaaaa tataatttgc aaagcaaaca acaccattgc tacagtataa
     9841 aaagcattat atgatttagt taataaaata atcaacaata ctatttcact tgacaagaaa
     9901 atataacata atatgtacaa aaatgatttt ttattttgtc ctactaaagt actataaata
     9961 tttttattat atttttttac aatccaggct tcaacaaata aaaggattat actcatataa
    10021 ccttctactt taataaaaac tgccgcaaaa gctagaatta tattaataaa tagatctaaa
    10081 gtacatacaa aaactattgc acctgctaca agtattttgt tatttttctt tttatatatt
    10141 acataaaaac ctattatctc agatatattt gctaaaagta agccaccata ttcatctaat
    10201 attatgctta ttatcgatcc tatagtaata actactaatg ttagtcccag ttttaaattt
    10261 atattcaatt ttatacgagt tattttaaga aacatccata aatctatggc actcgacaat
    10321 aaaaattgaa ctatagatag gtataagacc atattagatt acttgtgatg tttaaatata
    10381 ttacttaggt tttcccatag tcctctacct acataaccag aaattggtgc ttttttcccg
    10441 ccaacaacct tagttaattc tttttccttc aaaacagtct tcttaacaac tttcttcttc
    10501 atgatatttc atcctttcat gatttttata ctcaacttat ttacactctt aatatatcat
    10561 gcacttttaa acgaataaaa aaagatacca attcggtcat actttcgtac cgatctggca
    10621 tcttgcttaa ttctacttcc accaatttgg acgccatgga ggaatactgc caatggctct
    10681 catttgagca ccaccacctc taccgctacc tggcatacca tctggaccta cagcatgagg
    10741 aagcgctacc aagatcatat ctcttcggcc accaataacc tgacttaatt cttttctatt
    10801 caattgttct tgtctaagct tcattttcat cacctactaa ttgatttatt tataaatttt
    10861 gtatgaattt tgatatttaa ctccagggct cgacatttca ggttcatctc ttactactag
    10921 ccatttttga ccttaattaa atacgtcgtc taatcatgtc tgccatagcg attaatttac
    10981 tctctcgacc gccataacca ccatcaggtc ctaatctacg aatatagctt tttgctgaac
    11041 caccaattac gtcaatcaac tcattgtcac ttaaggtagt cttcttccat tcctgcatat
    11101 ttttcacctc tttaattaat ttatacttaa ataataatta aatttcggct attaaaacaa
    11161 aaaatactaa tttagcacat attttgacta aatcagatgt ttaattacta aatttttctt
    11221 tcaaatatat aaaaaacaac caagtattta acttggttgt ttccacaaat tagtatccca
    11281 ttgcattccg atcgccattt ttaattacat aataattacg ccaactgacg atccattcaa
    11341 taatcgcaat tcctattaca attacaaaga atacccaatt ttgtacaaaa taaattctca
    11401 ccataacagc tgccataacg ctaagagcta caatttcacc aattaaccat ttcctagcag
    11461 ctatgttaac tcttctcttg acttgataaa tggataagcc atagagacaa gtccagtacg
    11521 taaagtacaa cccagtaagg aatactgcac tcaacatgaa gtgataataa ttagtaactt
    11581 gacagtagat caacactgcc agttcagcaa taccgattat tgcagtcact gtttgagcta
    11641 atccgagcca gaactgatca gacttactta atcgatgttg ggaattacca attacttttt
    11701 cttccgcata ccctgcttca atatcaataa tgtagtagat tgttgcagca taacctacga
    11761 actgcaagaa tagtagcata ttgaaaatcc ataacgccaa ggttgctaca ccaaataaaa
    11821 gcatccctaa cgctgaccag gtagagagcc tatgtctttt ataacgaaaa aacatccgtc
    11881 caattctagt tctcattatt ctcacctact gcgataattc tcatcacatt gagtttaact
    11941 aaatgctatt cctatcttcc gaatcctggg aaatgacgaa acgattgaat acctccagta
    12001 ctaccaccca tactaccttc cattccatct ggacctaaca aacgtggtac cgaattcttc
    12061 atttcatata atgaaccacc gattactttt tctaattcac cattattcat tactttcaat
    12121 tttttcataa ttttcttcct ttcattaatt cagctacaat taaataataa ttaatatttt
    12181 tattaaaaat taaattatac tgatttggca gttttttact ctaaacttgt taaactcttc
    12241 caaatatttc ttacttacat tttcataatt ctatctgcat tatcatccat aaacttacat
    12301 ctttttccta ataacatgaa gatggctacc aaggatgatg ctgccattac aataaaagca
    12361 caagcccaat tatcaaaaaa tggagatatc gacacagtta atggcgtttc actaaagaca
    12421 atgaaatcta agccaaagtg aaccaacatg cttaaccata atttaccagt atataagtac
    12481 aaaactgcag ctaacatgcc aaatccaaag gtatagatca tttgctgttc aacttttgtc
    12541 aaattataaa gaacgccaaa ttgcgttgaa cccaaattag tcaaatgatc caagctaaat
    12601 aatagtgaag aaattacggt agcccacact acttttcctt taaaattacg aaagacaaat
    12661 aaaagtacaa caatatctaa acaacgttgc gtttcttcca tgattccggc ttctactgct
    12721 gaaagaaatc cagtcaacgt tacttcaaaa gtactaaaat cccagttaaa gatttgtacc
    12781 ggtgtttgtg ctatccccaa aaacacatta aaaaatggga aataagctga gaaaaggagc
    12841 agtagcacta atgcccacca ttgaaaattc ttagttttga taaatttcaa attccattca
    12901 aattttaatc cccatgcttt aaaaataaag aatgccagaa tgaacatggc aagtgcattt
    12961 ataagaccag attcaagtag ttcacttaca tatttgggcg cacaatagaa ttttaatgcg
    13021 ggagctaatt gacttagtcc caag
//
