LOCUS       c00014_JAAOXP0..       13045 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAAOXP010000003.1 Lactobacillus acidophilus strain BCRC 16099
            contig_3, whole genome shotgun sequence.
ACCESSION   JAAOXP010000003
VERSION     JAAOXP010000003
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-19 19:51:44
            Original ID  :: JAAOXP010000003.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 176356
            Orig. end    :: 189401
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13045
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[181356:184401]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8045
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..13045
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13045
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(44..466)
                     /locus_tag="ctg14_155"
                     /transl_table=11
                     /translation="MNNEKFARENKRIIEGMVIGAIAGPIVFLVLMYFKNPGPLQIWQI
                     FVSIALGIVMGLTLGGVMSASLVLNKTVESKIPWRKKVLKLAPQVIGTGVVVAAAGVVI
                     TLVTNWGSVDIVKTIFSTDTLWQFFDGVLLGLITIR"
     CDS             complement(500..694)
                     /locus_tag="ctg14_156"
                     /transl_table=11
                     /translation="MLYLIYIVLGLLIVLAVNYAVTAFLAVHDLLENREKDQLSFGDAF
                     KKYFAKNNNIPTKFSDLFN"
     CDS             complement(827..1036)
                     /locus_tag="ctg14_157"
                     /transl_table=11
                     /translation="MIEVTLDFMLLKRKMSSKELAEKVGITPANLSILKTGKAHGVRFD
                     TLSKICEVLDCQPGDLLVYKKDEE"
     CDS             complement(1051..1590)
                     /locus_tag="ctg14_158"
                     /transl_table=11
                     /translation="MKKFILNLLTVFAWIYQIFCVIGIIMGIVMIGVMPFGLKNPDFRA
                     GFESGRGIKGGSVDSYIGAIVVVLLSMIMMSVAAFLICRYARLIVKNIKQEVYFADSNL
                     NLLKKLLISVAGYTIISIVDFIMLMTHRAWFIKNANNVLYPSGVTTGLLFLAVLYVVYL
                     VFKYGMKVQEDADSII"
     CDS             complement(1595..1777)
                     /locus_tag="ctg14_159"
                     /transl_table=11
                     /translation="MLPDKKRQIGSIIGMLIMMAILVFANLGGTWSVLRITLLAIGVTG
                     VIGSAIYRIIQILGG"
     CDS             complement(1974..2189)
                     /locus_tag="ctg14_160"
                     /transl_table=11
                     /translation="MKQIIKRGEEKTSKQWMIFVSLVSVLIAGGLYSWVNQAMLHTDSF
                     VLQTVITLLLAYVFVFAFLFVKGSKK"
     CDS             complement(2207..2362)
                     /locus_tag="ctg14_161"
                     /transl_table=11
                     /translation="MKKKILESDLKNIKGGVAPIVYPIAGYVMKQMFEHSDQIIKGFKR
                     GWKKYK"
     CDS             complement(2366..2560)
                     /locus_tag="ctg14_162"
                     /transl_table=11
                     /translation="MNKFKDLNELELSNIAGGSNNIFWTRVGVGWAAEARCMIKPSLGN
                     WTTKAVSCGAKGLYAAVRG"
     CDS             complement(2726..2917)
                     /locus_tag="ctg14_163"
                     /transl_table=11
                     /translation="MKQIIITENKVILSKILGGSSSIDDIGLNDTEHMLPLYSKKGSNH
                     KRDVYLENPRYQTHFKFM"
     CDS             complement(2918..4234)
                     /locus_tag="ctg14_164"
                     /transl_table=11
                     /translation="MNKKNVSMLMLSPAILLMMNSTIVHADKGSTSHEISSKVVSKTKN
                     DDKNVPESEQETSSNNEIDQSQDKQEKEEQAIPEDQNDQSQNTNNQDPNDASEEDDEDE
                     VSVEDYENNVKDFHRVKMQEVKDLLAEKNNQEHLMYIGRPTCYYCRQFSPDLKDFNEIV
                     KGKLLYFNIDDEEGAHDYAFKVIGIPGTPTTMRFMNGKLISAWIGGEKTGQELHDFLYS
                     DTANKLVEQVVIKNQSNDTATQADNDVVASESDKTPEVTVEENNQAQSNNDVAITNFAE
                     NSVFENAKNVASSTADLTQVATGDQDDVAPKAETKNKTVKKPIKHKIVANKVKKQAKLH
                     KTNIIIPMSAKKREDVKENNQYDTVKVHGTSPNAIKDKQARITMLKELENDTSDTISTV
                     SLPSTGEKKNIWIQLMGMISVLVSVVLGISLRKKTKEEK"
     CDS             complement(4400..4990)
                     /locus_tag="ctg14_165"
                     /transl_table=11
                     /translation="MNSKDYESTEFYSYKFKNFSTMIIIPMALLVFILIIGSFFAIRQS
                     TVTSTGIVEPQSTLDIANKNYHEGQIIKRNRSKWMVHLDDKKENIVHLLPIIKAKKSVN
                     IVTYFPGNKIGAIKKGQPLHFQLSNANGTTDRLVGEVKEVGIYPVNLHGNNVYEVICKA
                     KLDKDVKYGMEGNATIITGKSTYFEYFKDKILN"
     CDS             complement(5001..7163)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 314.5; E-value:
                     2.4e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_166"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1076.1,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 5.1e-45, bitscore:
                     146.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLQYKSIYVPQVDESDCGVACLAMILKKYHSRVSLAHLRHSART
                     NLEGTTALGLVKTAQTFNLKTEAVKADMSLFDPDTDIQYPFIVHVLKQGELLHYYVVLK
                     ATKNYLVIADPDPSVGLTKMSKEKFSQEWTGIALFMVPNDDFEPVKEKKRNLWSLFPYM
                     FKQKKLVTNIILAALLMTIISICSSYFLQGLIDTYIPNGTYQTLSILAIGLLIAYVFNS
                     IFSYGQNFLLNILGQRLSIDLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDAL
                     ASTVISLFLDLSIVIVMGIVLAIQNSTLFMITLLALPVYAVVILSFSKKFEKLNNDQME
                     SNAVLSSSVIEDIQGIETIKALNSEQTRYRKIDSQFVDYLKKSFRYSKTESLQSALKTF
                     IQLSLNVIILWVGAKVVMNGQMSIGQLMTFNALLSYFVDPLQSIINLQPTLQSANVAQN
                     RLNEVYMVKSEFQKDVQIRDAKQLVGDIEYHNVDYHYGYGVDVLKDVNLKIKQNDKLAI
                     VGMSGSGKSTMVKLLVDFFSPSKGKLTFNGFDSTKVDKHVLRSYVNYVPQTPYIFSGTI
                     KENLLLGSRPDITEEDVLKACQIAEIESEIEQLPLQFETKMDENAKILSGGQKQRLTIA
                     RALLSPAKVLIFDEATSGLDTITEKKVVDNLMKLKNKTIIFIAHRLAIAQRTNNIVVVD
                     HGQIVEQGSHDELMQKHGFYYNLVEN"
     CDS             complement(7356..7760)
                     /locus_tag="ctg14_167"
                     /transl_table=11
                     /translation="MVKNKLVIKGITASIIYCLLGIIFDYIDSNLSIISIIENIGEGIV
                     FGLLMYWLLKSNNVRSISKHKINPLSSFVIGFFGSCLLLTLLLFLKIGYVSIDFYKSNF
                     YIISMIYLITGFIGGGALCFLSYVYRHKKE"
     CDS             complement(7794..8045)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_168"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.7e-18,
                     bitscore: 60.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKLMVLNEEKLSYVIGGGNPKVAHCASQIGRSTAWGAVSGAATG
                     TAVGQAVGALGGALFGGSMGVIKGSAACVSYLTRHRHH"
     CDS             complement(8238..9038)
                     /locus_tag="ctg14_169"
                     /transl_table=11
                     /translation="MSKFPIIVCDDDKDLANQLAKNINASIQDLTDDNESYTELDESVT
                     FVANDFAQAVGYVVANDIKNCIYFLDIKLSRESKAKNGVDLAEFIKKNDENAQIIFVTA
                     YDKYAPLTYRRRIGAIDYISKSMSSDKIIQRIEETLRNAFDNLSSRIKFGQRDFTYKIG
                     RRICKVAEDNILFIEHSTTQHKVHMVTENGEVEYKGNISQIDKENPFLVKVSQSYLVNP
                     RNINAIDMKEHTIIFDNDKMVTYSRAYKDVVKTLVNKFKDIEVK"
     CDS             complement(9031..10353)
                     /locus_tag="ctg14_170"
                     /transl_table=11
                     /translation="MVLYLSIVQFLLSSAIDLWMFLKITRIKLNINLKLGLTLVVITIG
                     SIISIILDEYGGLLLANISEIIGFYVIYKKKNNKILVAGAIVFVCTLDLFINIILAFAA
                     VFIKVEGYMSIILLFVEAWIVKKYNKNIYSTLVGQNKKSFLYILCYIFLSSEIVLLIIL
                     LTKSYNAFYTVAMVLFALQIIFSIVAYHEIVSIQQELLNKQKQKEILDNQHQLEEYASY
                     LEKSEDDLRAFRHDYKNILNSLKVSAQEGNVKEVIQKLDKYTETNLNSKALLKYKDVNH
                     IYVKSIKSIIISKLTELYNLNIPYNFECRSNIHNLPDHVNELDLVRIIGITFDNAIEES
                     KALVAEKHDIRSAEVQIMVYSDGPDEFEFEIRNKIQNKKISTSQIQQRGFTTKKDHKGL
                     GLANIKEIEGKYPDMSISYTIQDGWFDFYMTIDTEDGEDDE"
     CDS             complement(10360..10503)
                     /locus_tag="ctg14_171"
                     /transl_table=11
                     /translation="MKKKVVKKTVLKEKELTKVVGGKKAPISGYVGRGLWENLSNIFKH
                     HK"
     CDS             complement(10634..10825)
                     /locus_tag="ctg14_172"
                     /transl_table=11
                     /translation="MKLRQEQLNRKELSQVIGGRRDMILVALPHAVGPDGMPGSGRGGG
                     AQMRAIGSIPPWRPNWWK"
     CDS             complement(10938..11099)
                     /locus_tag="ctg14_173"
                     /transl_table=11
                     /translation="MQEWKKTTLSDNELIDVIGGSAKSYIRRLGPDGGYGGRESKLIAM
                     ADMIRRRI"
     CDS             complement(11271..11897)
                     /locus_tag="ctg14_174"
                     /transl_table=11
                     /translation="MRTRIGRMFFRYKRHRLSTWSALGMLLFGVATLALWIFNMLLFLQ
                     FVGYAATIYYIIDIEAGYAEEKVIGNSQHRLSKSDQFWLGLAQTVTAIIGIAELAVLIY
                     CQVTNYYHFMLSAVFLTGLYFTYWTCLYGLSIYQVKRRVNIAARKWLIGEIVALSVMAA
                     VMVRIYFVQNWVFFVIVIGIAIIEWIVSWRNYYVIKNGDRNAMGY"
     CDS             complement(11953..12129)
                     /locus_tag="ctg14_175"
                     /transl_table=11
                     /translation="MKKLKVMNNGELEKVIGGSLYEMKNSVPRLLGPDGMEGSMGGSTG
                     GIQSFRHFPGFGR"
ORIGIN
        1 attgtctttt agctttttcc aacatgatct atccctccac tttttatcta atggttatta
       61 gacctagaag tacaccgtca aagaactgcc ataaagtatc ggttgaaaaa attgttttta
      121 caatatcaac tgatccccaa ttggttacta aagtaatcac tacaccagct gcagcaacca
      181 ctactcctgt accaataact tgaggggcca gcttcaacac tttcttacgc catggaattt
      241 ttgactctac tgtcttatta aggactaaac ttgcggacat aacaccacct aatgtcaagc
      301 ccataacgat tccaagtgca atagaaacaa aaatctgcca aatttgaagt ggaccgggat
      361 ttttaaaata catcaacaca agaaatacta ttggtccagc aattgctccg attaccattc
      421 cctcaataat tctcttgttt tcacgagcaa atttttcgtt attcattttt cttacctcaa
      481 ggaaatttgt ttttcatttc taattaaaca aatccgaaaa cttagtcgga atattgttgt
      541 tcttggcgaa gtatttcttg aatgcatccc caaagcttaa ttgatctttt tctctatttt
      601 caagtaaatc gtgaacagcc aagaatgctg taacagcgta attaacggct aaaacgatta
      661 gcaagccaag cacaatgtaa attaagtaca gcatttttct ttcctccaat ttagcgatta
      721 tctcccaaga aataatctct tatcttttta aattaatcat atccccatca tttacataat
      781 tgccaaaacc gtccaattct gtcatttatc ggactgattt tgcattttat tcttcatctt
      841 ttttataaac taataaatcc cctggttgac aatccaagac ttcacagatc ttgctcaatg
      901 tgtcaaaacg aacgccatgt gcctttcctg tcttcagaat tgacaaatta gccggcgtga
      961 tgccaacctt ttctgctagc tcctttgaag acatctttcg cttcaagagc ataaaatcta
     1021 gtgtcacttc aatcatctat atcaaccttt ctaaataatc gagtctgcat cctcctgaac
     1081 tttcattccg tacttgaata ccaagtagac tacatatagt actgctagaa aaagtaatcc
     1141 agttgttaca ccgcttggat aaagtacatt attcgcattt ttaatgaacc aagcgcggtg
     1201 agtcattagc ataatgaaat ctactattga aatgatggta tatccagcaa ctgaaattaa
     1261 taattttttg agtaaattca aattactatc agcaaagtaa acttcttgct tgatattctt
     1321 aacaattaat ctggcatatc gacagatcaa aaaagctgca acgctcatca tgatcattga
     1381 cagcaacaca accactattg caccaatata gctatcaact gatccacctt ttatacccct
     1441 accactttca aaaccagcac gaaaatctgg attttttaag ccgaatggca taacacctat
     1501 cataacaatt cccataatta ttcctattac gcaaaatatt tggtaaatcc aagcaaaaac
     1561 tgtcaacaaa ttcaaaataa actttttcat ttttctatcc tcccaaaatc tgaatgattc
     1621 tgtatatagc actgccaatt acacccgtta ctccaattgc taataatgta attctaagaa
     1681 cactccatgt tccacctaag ttagcaaaca ctaagattgc catcattatc agcattccaa
     1741 taattgagcc tatttgtctt ttcttatctg gaagcatatc tatccctctc ttccatgaaa
     1801 ctatctatct ctttcttatt ccttttgata attattgtat tacgataatt tataattgca
     1861 atacagaaat aaaatatttt tttaggataa taaaaagcac caaattagtc gctaaactaa
     1921 cttgatgctt ttaatttatt catttctctc agctttgtct acagccttta atcctacttt
     1981 ttactgccct taacaaatag gaaagcaaat acgaaaacgt aagccagcag caaagtaatg
     2041 acagtttgta gaacgaaact atctgtatgt aacattgctt gattcaccca actatataat
     2101 ccaccagcaa ttagcacgct aactaaagac acaaagatca tccattgttt tgatgtcttt
     2161 tcttctccac gttttattat ttgtttcatt tttgggcatc ctcttgctat ttatattttt
     2221 tccatcctcg tttaaatccc tttattattt gatctgagtg ttcaaacatc tgtttcatta
     2281 catatcctgc tatcggatat actataggag ccaccccacc ctttatattt tttaaatctg
     2341 attctaatat tttctttttc attagttatc ccctcaccgc tgcatataat ccttttgctc
     2401 cacagcttac tgctttcgta gtccaattac cgagactggg tttgatcatg catctcgctt
     2461 ctgcagccca accaactccg actcttgtcc aaaaaatgtt gttacttccc ccagcaatat
     2521 tacttaattc taattcattc aaatctttaa atttattcat ctcaattacc tcctaataaa
     2581 aaacttattc aagtacaaat tcatattact aaaatttcta ttcttaaata gaaactggaa
     2641 taatttgact atctttataa ctaaaaacta ctttcatctt tatttcagta ttttagcgat
     2701 gccgttttgt atttaacatt gatcatcaca taaatttaaa atgtgtttgg tatctaggat
     2761 tctccaaata aacatctctt ttatgattgc tccctttctt actatacaaa ggtagcatat
     2821 gttcagtatc attcagacca atatcatcta tagaactcga tccacctaaa attttactta
     2881 aaatcacttt gttctcagta ataataattt gcttcattta cttttcctcc ttagttttct
     2941 ttcttaacga aatacctaaa actacactaa ctagaacact aatcattccc attaattgaa
     3001 tccagatatt tttcttctca ccagtagacg gcaaagacac agtagaaata gtatctgaag
     3061 tatcattctc aagttccttc aacatagtaa ttctagcttg tttgtcctta attgcattag
     3121 gagatgtacc gtgtactttt accgtatcat attgattatt ttcttttaca tcttcacgtt
     3181 ttttagcgga cataggtata ataatattcg tcttatgcaa tttagcttgt ttcttaacct
     3241 tattggctac aattttatgt tttattggtt tcttcacagt tttattttta gtttcagctt
     3301 taggagctac atcatcttga tcgcccgtcg ctacttgagt taaatccgca gtagaactag
     3361 caacattttt agcattttca aatacactat tctcagcgaa gttagtaata gcgacatcat
     3421 tattagactg cgcttgatta ttttcctcta cagtcacttc aggtgtttta tcgctctcag
     3481 atgcaacgac atcattatct gcttgagtag ccgtatcatt cgattgattt ttaattacaa
     3541 cctgttctac taatttatta gctgtgtcag aatacaaaaa atcatgtagc tcttgtcctg
     3601 ttttttctcc acctatccaa gcacttatca attttccatt cataaatctc atcgttgtag
     3661 gtgttcctgg aataccaata accttaaaag cataatcatg tgctccttct tcatcatcaa
     3721 tattgaaata aagcagctta cctttaacga tttcattgaa atcttttaaa tcaggtgaaa
     3781 attgtcggca gtaataacat gttgggcgac caatgtacat aagatgttct tgattatttt
     3841 tctctgctag aagatctttc acctcttgca ttttcactct atgaaaatct tttacattgt
     3901 tttcataatc ttcaacagat acttcatctt catcatcttc ttcacttgcg tcattaggat
     3961 cttgattatt tgtattctga gattgatcat tttgatcttc aggaattgct tgttcttctt
     4021 tttcctgctt atcttgagat tgatcaattt cgttattact actagtttct tgctcggatt
     4081 caggaacatt tttatcatca ttttttgttt tagatactac tttactacta atctcatgag
     4141 aagtactacc tttatccgca tgcacaatag tactattcat cattaataag attgctggac
     4201 ttaacattag cattgataca tttttcttat tcatagatat tccccatatc ttttataact
     4261 aagaaaaata tatcaattgt acactatatt tttggttatt agacttattc agtacacttt
     4321 ttaaccaaat cagttttctt taatcatggc aatcggaatt aatcccaatt aaaaaagagc
     4381 ttttcagctc tttttaattt tagttaagaa ttttatcctt aaaatattca aaatatgtgc
     4441 tctttcctgt aataattgtt gcattgcctt ccattccata cttcacatct ttatctaatt
     4501 tagctttaca aatcacttcg taaacattgt ttccgtgtaa gttaacaggg tatattccta
     4561 cttctttcac ttccccaact agtctatctg ttgttccatt ggcgttagat aattgaaaat
     4621 gtaagggttg tcctttttta attgcaccaa ttttattacc agggaaatat gtaacgatat
     4681 taactgattt ttttgcttta attattggta ataaatgcac tatattttct tttttatcat
     4741 ctagatgaac catccattta cttctatttc ttttaataat ttgtccctca tgataatttt
     4801 tattggcaat atcaagtgta ctttgtggtt ctacaattcc agtagatgta actgtactct
     4861 gtctgattgc aaagaaagag ccaattatca agataaatac taaaagtgcc ataggaatga
     4921 taatcatagt tgaaaaattt ttaaatttat aagaatagaa ttcagtactt tcatagtctt
     4981 tgctattcat aagttacctc ctaattttca actaagttat aatagaatcc atgtttttgc
     5041 attaattcat catggcttcc ttgctcaaca atttgaccat ggtctacaac cacaatatta
     5101 ttagtccttt gcgcaattgc taaacgatgg gcgataaaaa taatagtttt attcttcaat
     5161 ttcattaagt tatctactac ttttttctcc gtaatcgtat caagtccact tgtggcttca
     5221 tcaaaaatca aaaccttagc tggtgacaat aatgcacgtg caatagttaa cctttgcttt
     5281 tgtccaccgg ataaaatctt ggcattttca tccatcttag tttcaaattg caatggtaat
     5341 tgctcgattt cagactcaat ctctgctatc tggcaagctt tcaatacatc ttcttctgta
     5401 atatctggtc gactacctaa gagcagattt tctttgattg ttcctgaaaa gatgtatggt
     5461 gtttggggaa catagtttac gtatgaccgt aagacatgct tatctacttt agtagaatca
     5521 aatccattaa aagttaactt gcctttgctt ggagagaaaa aatcaactaa aagctttacc
     5581 atggttgact tgcctgagcc actcattcct acgatcgcca acttatcatt ctgcttaatc
     5641 tttaaattaa cgtcctttaa aacatcaact ccataaccat aatgataatc gacattatgg
     5701 tattcaatat ctcctactaa ttgctttgca tccctaatct ggacatcttt ctgaaactcg
     5761 ctcttaacca tgtatacttc attcaatcga ttttgagcta cattagcaga ctgtaaggtt
     5821 ggctgaagat taataatact ctgaagtgga tctacaaaat atgatagcaa tgcattaaat
     5881 gtcattaatt gaccgatact catctgaccg ttcattacaa ctttggctcc tacccaaagg
     5941 ataatcacat tgagagacag ttgaatgaaa gtctttagag ctgactgcaa agattcagtt
     6001 ttactgtaac gaaaggattt ctttagataa tcgacaaatt gactatcaat cttacggtac
     6061 cgtgtctgtt cactatttaa agccttgatc gtttcaatcc cttgaatatc ctcaattact
     6121 gaagaactta aaactgcatt actttccatc tgatcattgt tcagcttttc aaatttctta
     6181 gaaaagctaa gaatcactac agcgtatact ggcagtgcta acaaagtaat catgaataaa
     6241 gtagagtttt gaattgccaa aacaattccc attacaatta caattgaaag gtcaagaaat
     6301 aatgaaataa ctgtactagc taaggcgtca ataattcgac tagcatcaga gaatctagaa
     6361 gtgatttcac ctgttctacg agtcacaaaa aattccattg gtaattcaaa aatatggcga
     6421 atatattgta aattaagatc aatacttaat cgttgtccta agatatttaa caaaaagttt
     6481 tgaccataag aaaagatgga attaaagaca tatgctatca ataaaccgat ggctagaatt
     6541 gataaggttt gatatgtgcc attaggaata taagtatcaa ttaaaccttg taagaaatat
     6601 gaactacaaa tactaataat tgtcattaaa agggcggcca aaataatatt agtaactaat
     6661 ttcttttgct tgaacatata tggaaacaac gaccaaagat ttcgtttttt ctccttaact
     6721 ggctcaaaat cgtcattagg aaccataaaa agggcaatac cagtccattc ttgagagaat
     6781 ttttctttag acattttcgt taaaccaacg ctaggatctg gatcagcaat tactaaataa
     6841 tttttagttg ctttaagtac aacataatag tggagtaatt cgccttgttt taagacatga
     6901 acaataaaag gatattggat atccgtatct ggatcaaaca aggacatatc agctttgacc
     6961 gcttcagttt tcaaattaaa tgtttgtgct gttttgacta agccaagggc ggtagttcct
     7021 tctaaattag tacgtgctga atggcgcaaa tgtgctaatg atactctaga atgatatttc
     7081 ttaagaatca tagccaaaca ggcaacaccg caatctgatt cgtctacttg tggtacatag
     7141 attgatttat attgtagtag catagctctc cctaccttta cgtttttatt aagatatgtt
     7201 cattatttca tgacagaaga atcaaataaa aaaaatacca aattggttaa tttaataact
     7261 aatttagtat ttttaacatt tcaaaatagt aaactgacaa aaaatagatt agaaatatct
     7321 acaaactagt aaggttatgg attatcttaa agatgttact ctttcttatg tctataaaca
     7381 taggaaagaa aacataaagc tccaccacca ataaatccag taatcaagta aatcatacta
     7441 ataatataaa aattactctt ataaaaatca attgatacat aacctatttt tagaaataga
     7501 agtaaagtca gtaataaaca actgccgaag aaaccaataa caaatgaact taaaggatta
     7561 attttatgct ttgatattga tctaacatta ttacttttta atagccaata cataagtaag
     7621 ccgaatacta taccttctcc aatattttca ataattgaaa taattgataa attactatca
     7681 atatagtcaa atattattcc gagaagacaa tatataatac tagctgttat tcctttaata
     7741 accaatttat ttttaaccat attttttgcc tttcacattt tactcaaaaa caattaatga
     7801 tgtctatgac gcgttaaata acttacacat gctgctgagc ctttgataac gcccatactc
     7861 ccaccgaaaa gagcaccacc caatgcacca actgcctgac caactgcagt tccagtagct
     7921 gcaccgctaa ctgcacccca agccgttgat ctaccaattt gactagcaca atgtgctact
     7981 ttaggatttc ctccaccaat tacataactc aatttttctt catttaatac cattaacttt
     8041 tccattttag ttacctccta aataactact ttttgagatt tttatctcat ttcaacttac
     8101 atataaagga tatcaacata acagctatta gaaataaaat gaaccaatct agctatttta
     8161 taaactaata ctgttttctc atacgaattt ggtattatct ctaaaataaa aaaactggag
     8221 taaatccagt tttttaatta tttaacttca atatctttaa atttatttac aagtgtttta
     8281 accacatctt tgtacgctct agaataagtt accatcttat cattatcaaa tataatagta
     8341 tgttctttca tatcaatcgc attaatattt cttggattca ctaaataaga ctgagagact
     8401 tttactaaaa atgggttttc tttatcaatc tgactaatat ttcccttgta ttctacctct
     8461 ccattttcgg taaccatatg taccttatgc tgcgtagtac tatgttcaat aaaaagtata
     8521 ttgtcttcag ctactttaca tatacgccga ccaattttat aagtaaaatc acgttgacca
     8581 aacttaatcc tgctagataa attatcgaaa gcattacgca aagtttcctc aatacgctga
     8641 ataatcttat cagatgacat ggacttactt atatagtcaa ttgcaccgat acgacggcga
     8701 tatgttaacg gagcgtactt gtcgtacgcc gttacaaaga tgatctgggc attctcatca
     8761 ttcttcttaa tgaattcagc tagatctacg ccattcttag ctttagactc acggcttaat
     8821 ttaatatcta agaagtaaat acagttttta atatcatttg caacgacata tcctactgct
     8881 tgagcaaaat cattagcaac aaatgtaaca gattcatcca attcggtata actttcattg
     8941 tcatcagtta aatcttgaat agatgcatta atattcttag ccaattgatt agccaagtct
     9001 ttatcgtcgt cgcacacaat aattggaaat ttactcatca tcttcaccat cttccgtatc
     9061 aattgtcata tagaagtcaa accagccatc ttgaattgta taagaaatag acatatcagg
     9121 atatttaccc tcaatttctt taatattagc taatccgagt cccttatgat ctttcttagt
     9181 agtaaagcca cgttgttgaa tctgactagt tgagatcttt ttattttgaa ttttatttct
     9241 gatttcgaac tcaaactcat caggaccatc agagtagacc attatttgaa cttcagcgct
     9301 tctaatatca tgtttctcag caaccaaggc tttgctttct tcaattgcat tatcaaaggt
     9361 aataccaata atacgtacta gatcaagctc atttacatga tctggtaaat tatgaatatt
     9421 gcttcgacat tcgaagttat atggaatatt caaattgtat aattctgtta acttggaaat
     9481 aataatactc ttaattgatt taacgtaaat gtgatttacg tctttatatt tgagtagagc
     9541 cttagaattt aagttagttt cagtgtattt atctagtttc tgaattactt ctttaacgtt
     9601 gccctcttga gcacttacct ttaaagaatt aagaatattt ttgtaatcat gtctgaaggc
     9661 acggagatca tcttcacttt tttcaagata agaggcatat tcttcgagct gatgttgatt
     9721 atcaaggatc tctttttgct tttgtttatt taaaagttct tgctggatac taacaatttc
     9781 atgatatgca acgattgaaa atataatttg caaagcaaac aacaccattg ctacagtata
     9841 aaaagcatta tatgatttag ttaataaaat aatcaacaat actatttcac ttgacaagaa
     9901 aatataacat aatatgtaca aaaatgattt tttattttgt cctactaaag tactataaat
     9961 atttttatta tattttttta caatccaggc ttcaacaaat aaaaggatta tactcatata
    10021 accttctact ttaataaaaa ctgccgcaaa agctagaatt atattaataa atagatctaa
    10081 agtacataca aaaactattg cacctgctac aagtattttg ttatttttct ttttatatat
    10141 tacataaaaa cctattatct cagatatatt tgctaaaagt aagccaccat attcatctaa
    10201 tattatgctt attatcgatc ctatagtaat aactactaat gttagtccca gttttaaatt
    10261 tatattcaat tttatacgag ttattttaag aaacatccat aaatctatgg cactcgacaa
    10321 taaaaattga actatagata ggtataagac catattagat tacttgtgat gtttaaatat
    10381 attacttagg ttttcccata gtcctctacc tacataacca gaaattggtg cttttttccc
    10441 gccaacaacc ttagttaatt ctttttcctt caaaacagtc ttcttaacaa ctttcttctt
    10501 catgatattt catcctttca tgatttttat actcaactta tttacactct taatatatca
    10561 tgcactttta aacgaataaa aaaagatacc aattcggtca tactttcgta ccgatctggc
    10621 atcttgctta attctacttc caccaatttg gacgccatgg aggaatactg ccaatggctc
    10681 tcatttgagc accaccacct ctaccgctac ctggcatacc atctggacct acagcatgag
    10741 gaagcgctac caagatcata tctcttcggc caccaataac ctgacttaat tcttttctat
    10801 tcaattgttc ttgtctaagc ttcattttca tcacctacta attgatttat ttataaattt
    10861 tgtatgaatt ttgatattta actccagggc tcgacatttc aggttcatct cttactacta
    10921 gccatttttg accttaatta aatacgtcgt ctaatcatgt ctgccatagc gattaattta
    10981 ctctctcgac cgccataacc accatcaggt cctaatctac gaatatagct ttttgctgaa
    11041 ccaccaatta cgtcaatcaa ctcattgtca cttaaggtag tcttcttcca ttcctgcata
    11101 tttttcacct ctttaattaa tttatactta aataataatt aaatttcggc tattaaaaca
    11161 aaaaatacta atttagcaca tattttgact aaatcagatg tttaattact aaatttttct
    11221 ttcaaatata taaaaaacaa ccaagtattt aacttggttg tttccacaaa ttagtatccc
    11281 attgcattcc gatcgccatt tttaattaca taataattac gccaactgac gatccattca
    11341 ataatcgcaa ttcctattac aattacaaag aatacccaat tttgtacaaa ataaattctc
    11401 accataacag ctgccataac gctaagagct acaatttcac caattaacca tttcctagca
    11461 gctatgttaa ctcttctctt gacttgataa atggataagc catagagaca agtccagtac
    11521 gtaaagtaca acccagtaag gaatactgca ctcaacatga agtgataata attagtaact
    11581 tgacagtaga tcaacactgc cagttcagca ataccgatta ttgcagtcac tgtttgagct
    11641 aatccgagcc agaactgatc agacttactt aatcgatgtt gggaattacc aattactttt
    11701 tcttccgcat accctgcttc aatatcaata atgtagtaga ttgttgcagc ataacctacg
    11761 aactgcaaga atagtagcat attgaaaatc cataacgcca aggttgctac accaaataaa
    11821 agcatcccta acgctgacca ggtagagagc ctatgtcttt tataacgaaa aaacatccgt
    11881 ccaattctag ttctcattat tctcacctac tgcgataatt ctcatcacat tgagtttaac
    11941 taaatgctat tcctatcttc cgaatcctgg gaaatgacga aacgattgaa tacctccagt
    12001 actaccaccc atactacctt ccattccatc tggacctaac aaacgtggta ccgaattctt
    12061 catttcatat aatgaaccac cgattacttt ttctaattca ccattattca ttactttcaa
    12121 ttttttcata attttcttcc tttcattaat tcagctacaa ttaaataata attaatattt
    12181 ttattaaaaa ttaaattata ctgatttggc agttttttac tctaaacttg ttaaactctt
    12241 ccaaatattt cttacttaca ttttcataat tctatctgca ttatcatcca taaacttaca
    12301 tctttttcct aataacatga agatggctac caaggatgat gctgccatta caataaaagc
    12361 acaagcccaa ttatcaaaaa atggagatat cgacacagtt aatggcgttt cactaaagac
    12421 aatgaaatct aagccaaagt gaaccaacat gcttaaccat aatttaccag tatataagta
    12481 caaaactgca gctaacatgc caaatccaaa ggtatagatc atttgctgtt caacttttgt
    12541 caaattataa agaacgccaa attgcgttga acccaaatta gtcaaatgat ccaagctaaa
    12601 taatagtgaa gaaattacgg tagcccacac tacttttcct ttaaaattac gaaagacaaa
    12661 taaaagtaca acaatatcta aacaacgttg cgtttcttcc atgattccgg cttctactgc
    12721 tgaaagaaat ccagtcaacg ttacttcaaa agtactaaaa tcccagttaa agatttgtac
    12781 cggtgtttgt gctatcccca aaaacacatt aaaaaatggg aaataagctg agaaaaggag
    12841 cagtagcact aatgcccacc attgaaaatt cttagttttg ataaatttca aattccattc
    12901 aaattttaat ccccatgctt taaaaataaa gaatgccaga atgaacatgg caagtgcatt
    12961 tataagacca gattcaagta gttcacttac atatttgggc gcacaataga attttaatgc
    13021 gggagctaat tgacttagtc ccaag
//
