LOCUS       c00023_JAFIWI0..       22776 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAFIWI010000084.1 Lactobacillus helveticus strain 314
            NODE_15_length_36377_cov_60.523361, whole genome shotgun sequence.
ACCESSION   JAFIWI010000084
VERSION     JAFIWI010000084
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 09:40:16
            Original ID  :: JAFIWI010000084.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2637
            Orig. end    :: 25413
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22776
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[12637:15413]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12776
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..22776
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22776
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03882))"
                     /tool="antismash"
     CDS             17..223
                     /locus_tag="ctg23_6"
                     /transl_table=11
                     /translation="LITVKENASEILYLYLRDHGIKQNYVARKMEISSANFSSRLHGRL
                     KFNADFALAVAKALDIDPTIFLN"
     CDS             276..650
                     /locus_tag="ctg23_7"
                     /transl_table=11
                     /translation="VNKAFEGSKAFLNIPVGVARDKELLKKPKTILLMGEIVSMLNVTG
                     EFFMSNKKIAERLQVSTRTVNDYLDILEKKKLIIREKVVSDENNAIIGRKIRAGADLVK
                     YISLGWGSTFHQGSEEDFIP"
     CDS             650..1003
                     /locus_tag="ctg23_8"
                     /transl_table=11
                     /translation="VKPTSHKYNNINRTSNRAVNNSSSEKKEDPEREKIYKEFFFLARM
                     NDKQKQRSTNPSLDEIKQMRSLLYQCSINTLQATKDKFQQRMEWDMVGDPFAYLLKMLR
                     DGLANDRNFESWG"
     CDS             994..1350
                     /locus_tag="ctg23_9"
                     /transl_table=11
                     /translation="LGIKMQEEMSNTLINIASLTNLIKGIVNEAVKENEKDLTGKTWNV
                     NGFRRYCCRGKADNWVRTFIFDEFPEVDYKNGGFVVNPRRTPEGRTTLIFAKEACEWMQ
                     RHQHEIDWNAKLIN"
     CDS             1431..1823
                     /locus_tag="ctg23_10"
                     /transl_table=11
                     /translation="MKLSGKKENFDEFLFKVDELGYAINDLLPNNWMLNLRESTSLLND
                     LLDDKHLKFKQETVTSSDNIAIQIKTTLQDTDLQVFTSSVVILKSEDQIEYVLNWWLWQ
                     INCQLALIAEISNVFETAEEPECDAS"
     CDS             complement(1816..2415)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 31.7; E-value: 3.1e-09)"
                     /gene_kind="other"
                     /locus_tag="ctg23_11"
                     /transl_table=11
                     /translation="MKDKLKQSIIAITSANLKRILYSQKVTQRDLAALTGISIPSINRY
                     YLGNGAIPQSNLIKIAKALHVAPNELDPSYQPTKDFLSQLAEKSSDPDLKFRTEYLKQL
                     IQNSNLSVQELADKLSLKPITVYKWLAGVNTPSKENTAKLADLFNVSVDSLTDTSKELE
                     LTPQQKKILTALPSNLTDQQTDLIISLIKSVLTNTN"
     CDS             2579..2860
                     /locus_tag="ctg23_12"
                     /transl_table=11
                     /translation="MNSKNKKVAQALLDGRIDIQEIDDRLFAVMLLSMTGGLKLNKQKL
                     DEKEKLRLSSYLVSEVFGLMGNSPGVFDCRLHDMNYLVRISARSRKAQ"
     CDS             2835..3194
                     /locus_tag="ctg23_13"
                     /transl_table=11
                     /translation="VQDQEKLNEVQEKINSEKANHSSKENSKTKGKFDKTAWKKQHEQT
                     VEKLKKGLLKEVENYTQSPEKVVEMLDFMSKFHNYSERNALLIHMQRPGATAVGSYAKF
                     KKLGYNVKVKMVKRI"
     CDS             3200..4267
                     /locus_tag="ctg23_14"
                     /transl_table=11
                     /translation="LKNATKEEKQQIREGNIDSYQKTFYKIGTVFDAPQTNMPKEKYPE
                     LYPNRHQDFAVKNPGQLDLLEKGLRSVADDMQMPVVTYNPFDAEIRDKYKDPQNAKGYF
                     NRATNEIVLNGNNTPTENVSVLAHELGHAQLHNSQKQEKDLPRELKEMQAELTSYLYCS
                     HFGIDTKQETIDYIASWTSNGQKFNELPNGVKGQILTHVGSATRTLTTNTDKVIEKEQD
                     KIDQIAKENFLDTPEHSQWYLQKEKMEQEVSNNENNGTNFKSELTALRKIEDSMSRDEI
                     RKLDNAFTRTQSWQLDNTYSRVSNELRDEIKENQKKAEPVVSEEKINHATVKKTVSDEK
                     VREAIRQRRGQELDR"
     CDS             4502..4975
                     /locus_tag="ctg23_15"
                     /transl_table=11
                     /translation="MSFESKSQQQFSMPQIAKLEDILFNVVKPNREGYSKELIDSYYVI
                     DIVKPAQINKTDNLTVIKRKLIKYGLNAKNLKHDQVSDFITYINQDWTKNYGYAINDKI
                     YQKEKARLENKGIGFYLYSKYLNCNNDQQLYSYFKKMIEQMNKEILKSIKQVY"
     CDS             5097..7673
                     /locus_tag="ctg23_16"
                     /transl_table=11
                     /translation="VERLLILNEKKSQAEKFADYLGGMSGEFEGNHYDIVYAAGHLLQL
                     KAPGEMVDPKLAAKYSDWQNLDNFPWNPLDLNWSKTVISSKKKYISNIQENLSGHDVIV
                     IASDNDPSGEGDVLGWEIVDYLNWKNEVWRIRFKGDDSADYVIDALHKPEKSTIKNQDS
                     QGVLVKGKSRQRFDFLTGLEESRIATELAREQGYSNKGKALSIGRLQTYITSLVDQQNK
                     ARAAYVKKPFYEIRYKDTNGNTLKRDYQEGDTWRFAEKNLAEQDLMSYSPDQVIVDSTV
                     EKRKQPPKLVNLADLGKIFQKEYTTEQITDTYQKMYDDKIVSYPRTEDKAITIDDFNEL
                     LPYADKIATVVGIDPQLLRHKDPRKKFIIKSEDHGANRPTKLVPQSLEEVESKYGKCGR
                     DIYERVAKSYLAMLAEDYVYTQIKAHIANHPDFTSTINVPKELNYKLIFNESDSSEERQ
                     SGQQTKNFAENANPEVYQGTNTPPSKPTLTFILNNLDKWNLGTGATKMQTISKLQAIGK
                     ENKNVIPQLKVVKGVFEVTGTGALIACLAKDTYLSSGKITKRLQDILNEIKTDPAKKDM
                     VYSVAEKTIEYDRAIMIKNASLLKQDVQVKKLAGDLKAIERFSGVFVPTNEKINPSVII
                     FDGHKTTIEEQQKALAGEKIKYLIDRFGKKEEHTAYLAEQTYKSKKVGKEITKIDWKVE
                     FPEDTDHIKGLYLPLGKEIKFKKEYGRHIFSKEEATKLLAGEEISFGATNKQGKSFTVT
                     GKLTEQEFRDGRHKVKFWGFRINPKPVDTNIYEVITYKDGKEYHFKKIHRGHRWTPEEI
                     KRIAAGKKQIVAFNGRNGTYRMEIKPNPNKQYKGRKYFGFEEKFVK"
     CDS             7685..8371
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_17"
                     /sec_met_domain="Abi (E-value: 2.3e-19, bitscore: 61.2,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKQRILTKVTGIGQMIITFIVYALVQGVFMIRAKQLSMITVIFI
                     FGLTIALLSLIYEIYQRRLNQQNAWHFTSYSKSRMPKFSLKNWGYAFLGFLVICVLQIL
                     AGFLLKGEATNQATIAIHQQQLNPIINVMLVVIAPIFEEIIFRGIFFNWFFSDKPNSKA
                     TVFLAVLINGLIFGLLHEPQIDLFTGLYTLCGCVLATVYLKTKDLTFSYAAHLCNNLTV
                     FLISGL"
     CDS             8632..8772
                     /locus_tag="ctg23_18"
                     /transl_table=11
                     /translation="MSESTLLNLDISESSIQAFDEVEVSRRSRYSSCSCVNPPCPIAPV
                     D"
     CDS             8848..9060
                     /locus_tag="ctg23_19"
                     /transl_table=11
                     /translation="MVKVCVFPFVFVRQPILSTDVLFQKFNSIDELIEFYLNNDTILKA
                     LKDANPNVVDEMYRYKKGEITKKKE"
     CDS             9099..9824
                     /locus_tag="ctg23_20"
                     /transl_table=11
                     /translation="MGTRTTPFRLLTQECMASFDKDKHVHDYLTSNNTYMVGPCAIIDE
                     KNKGKIKLRASSIYVKKLKNIYLERQDNKEKTVIINNSDFLEFVLNSLHDWKLYVTLWN
                     TVKKEFPQISESNFIKYVNRLIMLGLLCSSYPSKYLKESLNFSVNSSKLPKNLEENVKK
                     VINFLSYFIDSKQEYLGWSRLENYFRENYEFERIPLSQVVYDDEFIFWKNTKENYKRRE
                     NYKLLQEYIDLKLKMDMKI"
     CDS             10001..11530
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     190.1; E-value: 8e-58)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_21"
                     /sec_met_domain="Lant_dehydr_N (E-value: 7.7e-35, bitscore:
                     111.5, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRQKFAEFSQNSLSVDNSIKAEVRYLFADTKFAAINNNFTSYKYE
                     INLNAPLDESKTELPISSLSVGIDQNGLYLWSEQLNKKVIPQFSNAINGLGVESEMYRF
                     LYLISRNRYEEFKPLLPYYLENKNWSPRLTYEDMIIKREEWRLDSVFLSEYKEDFNKAL
                     KDWQNRYNVPSIVGLSQGEAPIIYNLDNPLHLKLLKRFIMKKDLKQVSFVEVPEITEWH
                     ESKISQLSFSFYVPYECNDNNENSVFLTQKRIKTDKVSLLQGLISINIFPSSYLKDSLS
                     VVQKSIQNLNCKYFFINYLDNQRKSIRLRVWPINVVLLKNIFIRLDNLSAQKMIYDYQV
                     VNYLPEYSRYGGQSFYNQMLTAFYQDSKNALCTEGMNSSDKCLATIDSIIQILDFVTIK
                     SETWQQIQGFDEKLIDKHSSIIEKLERFNSKYNSKVKYQIQDDLGDYLKEIKLEYINNP
                     SKYYSILLSFIHMHVNRYLAPSKKEERDIYLSILEYYRIKEDAKKYGKVRK"
     CDS             11511..12776
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     227.1; E-value: 5.8e-69)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_22"
                     /sec_met_domain="LANC_like (E-value: 3.7e-34, bitscore:
                     109.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERLESKILFHSYKICVSECESALKDISLADGLAGISIFLSNFYK
                     SVDEDAVKNKIREINLRVITKAVKEINSQGTVLSLFGGLTGVGTACMEAMEYEEKYITL
                     LTKITKAVVEKVNVVFEDPNIYTNLTFQIYDLFNGAVGISLFLSKVYKKGVDIPNLGKA
                     IHCLTTFLIKVSVIDIKHFSESLLFLPADELPKSGDAQKLLPKGALLIGEAHGLAGILG
                     CLGTIYKIFPSLYLKKHIQNILEFLHRIRDDSVLYPEYVLSSKDNTPQVPHHKLNGGWC
                     FGSLGTTYSILLSSESIRNGGWADQAKKDLKFLFDNWKDDIRRDSLIMCHGLASQIYIA
                     NVLNKIYDDLHLEKTITEMISFTVHSANWKNKYLFSDVAMSLKGKKRYERGILEGELGV
                     SLVLNSVVSNIKWDADWIFLFG"
     CDS             12788..13903
                     /locus_tag="ctg23_23"
                     /transl_table=11
                     /translation="MKSQYFQANFRIARKSKKNMLLAILLVVCMIFAVLVVEKQKINDG
                     YRQWRDYNESVHVNADYFSSNLLRKKDYKQTFNNLNKQAEYLAGVQNGEVFDSPQDYLQ
                     NSKKLVQTMLAGYQNNYRGASTLNVPPKYQLRQKLVVYDYLYQHHLAIVMNSKESSTYL
                     IYILGLVGMFLFFYVLFIASDSWMINLSHPTLLKNIPYQIRDEVEGKFIINLALTLLLL
                     VIGMLGSYLFAGFKNGFNSLNYPAVLYFGKISAVPLWLYCLLYLTYAVILVMFVTSLAL
                     LLNQLTHSVYLTIFIAALVYSISLLPGSIAKYLFFLPSAYLNISSVLDGTVASQSIIPA
                     NWAVGMTILLVWTVVLVIWFRHLVNQGGVEK"
     CDS             13900..15141
                     /locus_tag="ctg23_24"
                     /transl_table=11
                     /translation="MKKQYFLFQLKMFLTNPKNVGLFAITIVFALYFGLVSAPQHHVIE
                     NVDPYAITKEYQDDQAFLKVAEKEFAQADKGTSDYDPSEGTKDAITTYPTIIKYDHERL
                     KALKNHDWRLYTKYSSNWYQKMDNLIWVKENQNYMYPLEYYHNNNYKEDGHFGYQRTFH
                     FYDGLLKSQAKLNKNVLEERTTLQRLQQSLSGWTMIILIVIVVLFAADMITNDQKYRTV
                     VKNIPLSKRTILWLKTAVIEVGVLFNFLVAFLVVTLCTAPRYGFGSFNLLTPIYTGRLY
                     FKTPFVYQTLGQYYLGFLLFAVVITFIFIRLTLLLSLIFRNEYVAAIISSILAMSAKVL
                     YFSLGMGFVYPFLKQLPMTYFTIGESLTSNLSYLMDSPGWGFSDGLVPLLIFAIAIEAV
                     IWLFCQFRNLVLVK"
     CDS             15150..16016
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 149.2; E-value:
                     2.6e-45)"
                     /gene_kind="transport"
                     /locus_tag="ctg23_25"
                     /transl_table=11
                     /translation="MLKINNVKLAFGKHVVLDQINLAFQAGTIVGLVAPNGTGKSTLLN
                     VILHNLEPQAGYVEYDHLRYRSNREIIKLHQLICAFPDQSDLVPFMSGRDHLKLYADLW
                     GNSDKKVDEIINQLQMADYVDRPTHTYSLGMKQRLCFAMVVAADTPVMLLDEVMNGLDP
                     QNVQLISNCLLKLKKENKLIIMASHLLNNLQSYADRVLFLKAGKVIEDLDNQHQTKQYL
                     KTEANEQVEALLKDKKFTKLPDNKIILPLEDNDPELDQLVLQMTKQKIPYSIGRIDLTE
                     LFSKFYG"
     CDS             complement(16061..16489)
                     /locus_tag="ctg23_26"
                     /transl_table=11
                     /translation="LTPYSCTILINFMKKDKIVVFPIIIKPTNDSKIKYTVNVPDLDRD
                     TQGKTIAEAIDMGKDLIGTMSLVEDLPKSNVKIPKTKNDEIATLVTVNISEYKRKNDER
                     VVKKTLTIPNYLNEEGKAAGLNFSAILSDGIKAKLGIK"
     CDS             complement(16502..16681)
                     /locus_tag="ctg23_27"
                     /transl_table=11
                     /translation="MVKRRDALKILKKNGWWLDRHGTNHDVYTDGHHSEPIPRHGDMNK
                     ITWLKIMKRNNLKG"
     CDS             16880..17017
                     /locus_tag="ctg23_28"
                     /transl_table=11
                     /translation="MNNNSKRKANKFDEDFVAWMLVTQAVVVAACAYLVSTGFFTTLPV
                     "
     CDS             17079..17870
                     /gene_functions="other (smcogs) SMCOG1157:hypothetical
                     protein (Score: 155.2; E-value: 3.7e-47)"
                     /gene_kind="other"
                     /locus_tag="ctg23_29"
                     /transl_table=11
                     /translation="MKIITFAAIKGGVGKTTLAYNYGEWLANQGSRILFIDLDHQSNLT
                     QTYQIYDNKYTVGNIFLKNDQVKIHQINENIDLIAGDMHLDDIEADIETKVDKNMLLYM
                     WLADNYDTRSLDQYDYIIIDCHPDFSIATKNAVIISDDILSPITPSEHGYSAKFNLEER
                     FKELKRETIDYSTRQSLVDAKLLFVGNMIKNNTRSSHELLEVLKKDPSVIAKIPNRELF
                     NRSTLDKVAISTIMKDKTMEHKYGAFFSELNDIFDSITNNV"
     CDS             17938..18195
                     /locus_tag="ctg23_30"
                     /transl_table=11
                     /translation="MSFNPNQGKKFAAALKESKPKLNEQDSDVQDSTEENSNYIKREKR
                     KPYTFSLMPSARIKLTESAKEHGYNSSSNYLNDAILNGKL"
     CDS             18525..18761
                     /locus_tag="ctg23_31"
                     /transl_table=11
                     /translation="MKIGEALKEERINLGMSKYQFSKGIVDRKFYGKVEKEEGTISSKK
                     LLLLLQKNDINFQEFFCKLQSKEKLVNFNLKKN"
     CDS             18785..19357
                     /locus_tag="ctg23_32"
                     /transl_table=11
                     /translation="MREAFNRKDLQKCKRICQQILKLKDEKILKLRAIVATYYLEDKLD
                     YLKDSIKKEIVSEIYNSKNITKNTPIIQLFSNVMPILSNDQLNILILEFLRRYENSNKK
                     TEMDRKRIAVLLNNYLVTCYEKGIDGDVVDKTISCLMNMQDVHLLIYKEVGKFYFELIK
                     GNKTNALKIKQELKNWNYTNLTEKLKI"
     CDS             19586..19780
                     /locus_tag="ctg23_33"
                     /transl_table=11
                     /translation="VAVPSFTLKCGYSLIVSKEGEKMYNKLVGLQKMQVRKSSKRNNSF
                     ISIACVDKSTISLFACPGK"
     CDS             19807..20427
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 113.9; E-value:
                     1.6e-34)"
                     /gene_kind="transport"
                     /locus_tag="ctg23_34"
                     /transl_table=11
                     /translation="VQYTIKTTDVTLRFHFDVNHNDRILIIGKSGVGKSTLLKIIDGNI
                     IPDKGKVVELINKRIFLNPFNDIAYINQTPYIFSASIMENITLFDNKVDYHKVQKILNE
                     VNLNSFSKEKLEDIKLEKNGISVSGGQKQKIEIARALFSHKSLILADEITANLDRNNAK
                     KIRDLLFRIPNPVIEVAHHFNENDRRYTKVFRLDADGSLKRIR"
     CDS             20496..22058
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 123.6; E-value:
                     1.7e-37)"
                     /gene_kind="transport"
                     /locus_tag="ctg23_35"
                     /transl_table=11
                     /translation="LDEISFSVYKGEIVALVGHNGVGKTTLMKCILGTTGYDKGIKIFE
                     GNKIKNKQCLREIGGLIEQPGIYNFLTGMENLELLNYNHGAQDLNYLLNKFNMKSYLNK
                     KVATYSLGIRQKLGIIEAFLMGNKLVILDEPINALDPISVKEFREAVEHFRNKGVSFLI
                     SSHIISETAKVADKILVLNKSQLTEIKMKDNEEKTLIIKTSNDNKLEALLQKDNVEYSL
                     RTNKVMIKCSSFFQAGQYVTKIIKAGIDITYLDLSKDSLENKILKIMGKKMISLINIEL
                     KKISKRLQTKIAACILIFFYLAIVIATKYFHAFDSKFAVENSFSTLQFIPIVLIIFTTS
                     SVTVEYQSGAIKTLIYNVKQRYKIVISKFLALVIINFFMYLIILMANILITKYLFSEIA
                     SKKILTYASLWVMGYSIENLYLISFAFLLAIIFSNQAISVSLSVISYFLVNLIDGSMFS
                     AIRNYNVLKYNPVNLFNFKMQIVMPSFAAKTCLSLSEFGCLFAIYIFINIILSIFILNT
                     KDF"
     CDS             22628..22753
                     /locus_tag="ctg23_36"
                     /transl_table=11
                     /translation="MLDMIQAFNLSWNKEQLLPDEGRANCHRQPMSVGPEHFCSR"
ORIGIN
        1 aaatcgaggt gataaattga ttactgtgaa agaaaatgcc agtgagattt tatatttata
       61 tttaagagat catgggatta aacagaatta tgtagcacgt aaaatggaaa taagcagtgc
      121 aaactttagt agtcgcttac atggtcgttt aaagtttaat gctgactttg cactggcagt
      181 agcaaaagcg ttagatattg atcccactat ttttttaaac tgaatttatt caaattggat
      241 aattaaacat cttaacttgg aaagtaggaa ttaaagtgaa caaagcattt gaaggatcaa
      301 aagctttttt gaatattcca gtaggggtag cgagagataa ggaactacta aaaaaaccta
      361 aaaccattct cctaatgggt gaaattgttt caatgctgaa cgttactggt gaattcttta
      421 tgagtaataa gaaaattgct gaacgattgc aggtttctac acgtactgta aatgattacc
      481 tagatattct ggagaagaaa aagttaatta tacgtgaaaa agttgtaagt gatgaaaata
      541 atgcgatcat tggcaggaaa atacgtgctg gtgcagacct agtgaaatac atttcactag
      601 ggtggggaag tacatttcat cagggtagtg aagaggactt cataccctag tgaagcctac
      661 ttcacataaa tataacaata ttaatagaac atctaataga gcagttaata attcttcttc
      721 tgagaagaaa gaagatccag aaagagaaaa gatttataaa gagtttttct ttttggctag
      781 gatgaatgat aagcaaaaac aacgatccac taatccttct ttagatgaga ttaaacagat
      841 gcgaagtctg ctgtaccaat gtagtataaa cacacttcaa gcaactaaag ataagttcca
      901 gcaaaggatg gaatgggata tggttggtga tccatttgct tatctactaa agatgctaag
      961 agatggctta gcaaacgata ggaattttga aagttgggga taaaaatgca agaagaaatg
     1021 tcaaacactt taattaatat tgcaagcctt acaaacctta ttaaaggtat cgttaatgaa
     1081 gctgttaaag aaaatgaaaa agatttaaca ggcaagactt ggaatgtcaa tgggtttaga
     1141 cggtattgtt gtcgtggtaa agctgataac tgggttagaa cctttatctt tgatgagttt
     1201 cctgaggttg attataaaaa tggtggtttt gttgtaaatc ctagaaggac acctgaaggc
     1261 agaactacac tcatttttgc taaagaagcc tgtgaatgga tgcaacgtca ccaacatgaa
     1321 attgactgga atgccaaact cattaactaa ttcaatggta aaaaatgcaa ataaataacg
     1381 ctcttcaata ataggagcga tatagattta gatgagaatg gagaaaagaa atgaaattat
     1441 caggtaagaa agaaaatttt gatgaatttt tgttcaaggt agatgagtta ggctacgcca
     1501 ttaacgattt attgcctaac aattggatgc tgaacttaag agagtctacg agtttattga
     1561 atgatctgct tgacgataaa catctaaagt ttaagcagga gactgtgacc tcatcagata
     1621 atattgcaat tcagattaaa acaactttac aagatacgga tttacaagta ttcaccagtt
     1681 cagttgtaat attaaaatca gaggatcaaa tcgagtatgt tttaaactgg tggttatggc
     1741 aaattaactg ccaattagca ttaattgctg aaatttcaaa tgtatttgaa actgctgaag
     1801 aaccagaatg tgatgctagt tagtattagt taacacagat ttgattaaag agatgattag
     1861 atcagtttgc tgatcagtta gatttgatgg taaagcagtt aagatttttt tctgttgtgg
     1921 tgttaattca agttctttgg aggtatccgt taaagaatca acactaacgt taaataaatc
     1981 ggctaattta gctgtgtttt ccttgctagg tgtatttact cctgcaagcc atttataaac
     2041 tgtaatcggt tttaaactaa gtttatcagc aagctcttga actgataaat tactgttctg
     2101 aattagttgc ttaaggtatt cagttctaaa ctttaagtct ggatcagatg atttttcagc
     2161 taattgagac aaaaagtctt tagtgggttg atatgaagga tcaagttcat taggtgcaac
     2221 atgcaaggct ttagcaatct taatcaaatt gctctgtggg attgcaccat ttcctaaata
     2281 ataacgatta attgaaggaa tggagatccc agttagtgca gctaagtctc gctgcgttac
     2341 tttctgacta tataaaattc tttttaagtt agcactagtt attgcaatga tagattgttt
     2401 aagcttgtct ttcataataa ttacctcttt aaatcttcaa agtactaaat cattactaat
     2461 atatcatttt tacgatattt ttgtataaaa ttacaagatt tatataaagt cgaaatgaaa
     2521 ttaattagaa atcgtattaa aaaaacagaa agcataggaa ctacgaggaa gaatgaaaat
     2581 gaactcaaaa aataaaaaag tcgcacaagc tttacttgat ggcagaatag atattcaaga
     2641 aattgatgat aggttgtttg ctgtcatgtt gcttagtatg acaggtggtc ttaaattaaa
     2701 taaacaaaaa cttgatgaga aggaaaaatt aagattaagc agttatttag ttagtgaagt
     2761 atttggattg atgggaaata gtccaggagt ctttgattgt cgactccatg atatgaacta
     2821 tcttgtaaga attagtgcaa gatcaagaaa agctcaatga agttcaggaa aaaattaatt
     2881 ctgaaaaagc taatcactca tcaaaagaaa atagcaagac taaaggtaag tttgataaaa
     2941 cagcttggaa aaaacaacat gaacaaacag ttgaaaaatt aaaaaaaggc ttgcttaaag
     3001 aagtagaaaa ttatactcaa tcacctgaaa aagttgtgga gatgcttgat tttatgagta
     3061 aatttcacaa ctactctgaa aggaatgcat tgttgattca tatgcaacga cctggtgcaa
     3121 ctgcggtagg atcttatgct aaatttaaaa agctaggcta caacgtcaag gtaaagatgg
     3181 taaaaagaat ttaactagtt tgaaaaatgc aaccaaagaa gaaaaacaac aaatcaggga
     3241 gggtaacata gacagttatc aaaagacttt ctataagatt ggtactgttt tcgatgctcc
     3301 tcaaactaat atgcctaagg aaaaatatcc agagctttat cctaatagac atcaagattt
     3361 tgctgtgaag aatccaggtc agcttgattt actagaaaaa ggattaagaa gtgtggctga
     3421 tgatatgcaa atgccggttg tcacttacaa tccatttgat gcagaaattc gtgataagta
     3481 taaagatcca cagaatgcaa agggatactt taatagagct actaatgaga tagtactaaa
     3541 tggcaacaat actccgacag aaaatgtttc agtcttagct catgaacttg gacatgcaca
     3601 gctacataat agtcaaaagc aagaaaaaga tttgcctaga gaattgaagg aaatgcaagc
     3661 agaacttacc agctatttgt attgttccca ttttggaatt gataccaagc aagaaactat
     3721 tgactatatt gctagttgga caagtaatgg acaaaagttt aatgagttgc ctaatggtgt
     3781 taagggacaa atacttacac acgtgggttc agcaaccaga acacttacaa caaatactga
     3841 taaagtaatt gaaaaagaac aagataaaat tgatcagatt gctaaagaaa acttcttaga
     3901 tactcccgag cattcacaat ggtacttgca aaaggaaaag atggaacaag aagtatcaaa
     3961 caatgaaaat aatggaacta atttcaaatc ggaactgaca gcattaagaa aaattgaaga
     4021 tagtatgtca agagatgaga ttagaaagtt agataatgcc tttactagaa ctcagagctg
     4081 gcagttagat aatacttata gccgagtatc gaatgaatta agggatgaaa ttaaggaaaa
     4141 tcagaaaaaa gccgagccag ttgtcagtga ggagaagatt aatcatgcta cagtgaaaaa
     4201 aactgtaagt gatgaaaagg ttagggaggc aattcggcaa agaagaggac aagagctaga
     4261 tcgttaatag ttgaaaaaat gaaaaatgta aaaagaaagc agttagtgat gcaaaaacta
     4321 actgcttttt ttgtacaggg aaatagtgag ctaaagtcca tataaatgac atatacatta
     4381 cttatatgta gcatataagt acattgcatg tttggactat taaaaaagtt gatgatattc
     4441 taaatatcat aaaatagata tataatatag tcaaagtggt ttaaatagca aggagaatat
     4501 tatgagtttt gaatcaaaat cccaacagca gttttctatg ccacaaattg caaagttaga
     4561 agatatttta tttaacgttg tcaaacctaa tcgagaagga tactctaaag aattgatcga
     4621 ttcttattat gtaattgata tagttaaacc agcacaaatc aacaaaacag acaatttaac
     4681 tgtaatcaaa agaaaattaa ttaagtatgg cttgaatgct aagaacctaa agcatgacca
     4741 agtaagcgac ttcattactt atattaatca agattggaca aaaaattatg gttatgcaat
     4801 taatgacaag atttatcaaa aggaaaaggc aagactagaa aataagggaa ttggttttta
     4861 cttgtattcc aagtatctta attgcaacaa tgaccagcaa ttatattcat actttaagaa
     4921 aatgattgaa caaatgaata aagagatttt gaaaagcatt aagcaggttt actagctttt
     4981 tatatatcat aaatatgaca tataatataa gcacctccat taatcatttt tgaataatga
     5041 ttatgctatg tgaagaatac cgtgaggtat tcttttttat tgaaaggaat aggaacgtgg
     5101 aaagattatt aattttaaat gaaaagaagt ctcaagcaga aaaatttgca gattatttag
     5161 gtggaatgag cggtgaattt gaaggtaatc attatgatat tgtttatgct gcaggacatt
     5221 tattgcagct taaagcacct ggtgaaatgg ttgatcctaa acttgcagcc aaatattccg
     5281 attggcaaaa tttggataat tttccttgga atcctcttga tttaaattgg tcaaaaacgg
     5341 ttattagttc aaagaaaaaa tatattagta atattcaaga aaacctatct ggacatgatg
     5401 tgattgttat tgcaagtgat aatgatccat ctggtgaggg tgatgtactg ggctgggaaa
     5461 tagtagatta cttaaattgg aaaaatgaag tctggcggat tcgctttaaa ggtgacgatt
     5521 cagccgatta tgtcattgat gcattacata agccagaaaa atcaacgata aaaaatcaag
     5581 attcacaagg tgttttggta aaaggaaaat caagacaaag atttgatttt ttgacaggtt
     5641 tagaagaatc aagaattgca actgaattag ctagagaaca aggctacagc aataaaggta
     5701 aggctctttc gattggtcgc ttacagacat acattacttc tttagttgat caacaaaata
     5761 aagcgagagc agcatatgtc aagaagcctt tctatgaaat aaggtataag gacacgaacg
     5821 gtaatacgtt aaaacgtgat tatcaagagg gtgatacctg gcgttttgcg gagaaaaatt
     5881 tagctgagca agatttgatg agctatagtc cagatcaagt tatcgttgac agcactgttg
     5941 aaaagagaaa gcagccgcct aagctggtca acttagcaga tttgggtaaa atctttcaaa
     6001 aagaatatac gactgaacaa attacagata cttatcaaaa aatgtatgat gataaaattg
     6061 tttcttaccc aagaacagaa gataaagcaa ttacgattga tgactttaat gaactattac
     6121 cgtatgcaga taagattgca acagttgttg gaattgatcc acaactttta aggcataaag
     6181 atccccgtaa aaagttcatc attaagagtg aagatcacgg tgctaatcgc ccaaccaaat
     6241 tagtaccaca atcacttgaa gaagttgaaa gcaaatatgg taaatgcggt cgagatattt
     6301 atgaaagagt cgcaaagtct tatttagcta tgctggctga agattatgtt tatacccaga
     6361 ttaaagccca catcgcaaat catcctgatt ttacaagtac tattaatgtc cctaaagaat
     6421 taaattataa acttattttc aatgaatcag attcaagtga agaacgacaa tctggacaac
     6481 aaactaaaaa ttttgcagaa aatgctaatc ccgaagtata tcagggcaca aatacgccac
     6541 catcaaagcc tactttaacc tttattctaa ataatttaga taaatggaac ttgggtacag
     6601 gtgccaccaa aatgcagaca atcagtaaac ttcaagcaat tggtaaagaa aataagaatg
     6661 ttattcctca actaaaagta gtaaaagggg tatttgaagt cactggaact ggtgctttaa
     6721 ttgcttgctt ggctaaagat acgtatctat cttcagggaa aataactaag cgtttgcaag
     6781 atattttaaa tgaaattaag actgatccag ctaagaaaga tatggtgtat tcagttgcag
     6841 aaaaaacaat tgaatacgat agggcgatta tgattaaaaa tgcttcgtta ttaaagcaag
     6901 atgttcaagt taagaaatta gctggcgatt taaaggcaat tgaacgtttc agtggtgttt
     6961 ttgtcccgac aaatgagaaa atcaatccat cagtaataat ttttgatgga cataaaacta
     7021 ctatcgaaga gcagcaaaaa gctttagcgg gtgaaaaaat caaatattta attgatagat
     7081 tcggtaaaaa agaggagcat actgcctatt tagcggaaca aacgtataaa agcaaaaagg
     7141 taggcaaaga aatcactaaa attgattgga aagtagagtt tcctgaagat actgatcaca
     7201 tcaaaggatt gtatctgccg ttaggcaaag aaattaaatt taagaaagaa tatggacgac
     7261 atatctttag taaagaagaa gctactaaat tattagctgg tgaagaaatt agttttggag
     7321 caactaataa gcaggggaaa agttttacag taactggaaa gctgacagaa caagaattta
     7381 gagatggtcg tcataaagta aagttctggg gctttagaat taatcccaaa cctgttgata
     7441 caaatattta tgaagtaatt acttataagg atggcaagga atatcatttt aagaaaatac
     7501 accgaggaca tcgttggaca ccagaagaaa ttaagagaat cgcggcaggt aagaaacaga
     7561 tcgtagcttt caatggccga aatggcacct atcgaatgga aattaaacct aatccaaata
     7621 agcaatacaa aggaagaaag tatttcggtt ttgaagaaaa gtttgttaag taggagttgg
     7681 tacgatgaat aagcagagaa tccttactaa agtaactggt attggtcaaa tgattataac
     7741 tttcatagtc tatgcattag ttcaaggggt atttatgatt agagcaaaac aattaagcat
     7801 gatcactgtt atcttcatat ttggattgac gatagctctt ttaagtttga tttatgaaat
     7861 atatcaaaga aggcttaatc agcaaaatgc ttggcacttt actagttata gcaaaagcag
     7921 aatgccgaag ttttctttaa agaattgggg ctatgcattt ttagggtttc tggtaatttg
     7981 tgtgttgcaa attttagcag gatttttgct taagggagaa gccactaacc aagctacaat
     8041 agccattcat caacaacagc taaatccaat cattaatgtg atgctggtag taattgcacc
     8101 aatctttgaa gaaattattt ttagaggtat tttctttaat tggttcttta gtgataagcc
     8161 aaacagtaaa gcaacagtat ttttagcagt cctcattaat ggattgattt ttggacttct
     8221 gcatgaacca cagattgact tgtttactgg actatataca ttatgtggct gtgttttagc
     8281 tacagtgtac ctaaagacta aagatttgac tttttcttat gcagctcatc tttgcaataa
     8341 tttaaccgta tttttgataa gcggtttgta atagtgctac gaataaacaa tgcgtaagaa
     8401 attagcagta cttaaaattt tagatcgttc tccattaaaa tgtcttatta tagtaataaa
     8461 aatgaaaaaa tattaaagaa ataattgaaa tttattttta atttattata atttaatcaa
     8521 gaaataatta aatcagacca aagtacaaaa acttagcttt atatcaagtt agatcgtaca
     8581 tactgattaa ttatttcgtt attcattaac atttattagg aggtattaat tatgtcagaa
     8641 tcaacattat taaatttgga tattagcgaa agttcaatcc aagcatttga tgaggtagag
     8701 gtaagtagac gttcaagata ttcttcttgt tcttgtgtta acccaccttg tcctattgca
     8761 ccagtggatt aaacaatcgc tacatagtaa gaattaagaa agctcttagg aattcctaag
     8821 agctttctta ataaggggga gattgaaatg gttaaagtat gtgtatttcc atttgtattt
     8881 gtacgccaac cgattttatc cacagatgtt ttattccaaa aatttaatag catagatgaa
     8941 ttaatagagt tttatttaaa taacgataca attcttaaag cacttaaaga tgcaaatcca
     9001 aatgtagttg atgaaatgta tagatataaa aagggtgaaa taacaaaaaa aaaagagtaa
     9061 gaaatttatt tttaactatg gagaattatt ttatccgaat ggggaccaga acaacgccgt
     9121 ttagattatt aactcaggag tgtatggcat cttttgataa agacaaacat gttcatgatt
     9181 atttgacatc gaataataca tatatggttg gtccgtgtgc aataattgat gaaaaaaata
     9241 aaggaaaaat taaattacga gcatctagca tatatgtgaa aaaactaaaa aatatatatt
     9301 tagagaggca ggataataaa gaaaagactg taatcattaa taatagtgac tttttagagt
     9361 ttgttttgaa tagcttacat gattggaaac tatacgttac tttatggaat acagtgaaga
     9421 aagaatttcc acagatctcg gaatcaaatt ttattaagta tgtaaataga cttattatgt
     9481 tgggtttgct atgcagctct taccctagta agtatttaaa agaatcactt aatttttcag
     9541 ttaatagctc gaaattgcct aagaatttgg aagagaatgt aaaaaaagtg attaattttt
     9601 tatcatattt tatagattcg aaacaagaat atttaggctg gagtagatta gaaaattatt
     9661 ttagggaaaa ttatgaattt gagcgtatac ctttgtctca agtagtctat gatgatgaat
     9721 tcattttttg gaagaatacg aaggaaaatt ataagagaag agaaaattat aaattattac
     9781 aagaatatat tgatttgaaa ttaaaaatgg acatgaaaat atagatattt cccagtcact
     9841 tatatcgaga ttgaaaaata ctaacagtaa ttatgcacta tctggggatt tactacttag
     9901 ttattctggc tctcaaaaca agattgttat tgattctggt attggaagtt caagaagtgg
     9961 gaagattgtt gggagatttg taaatttatt ttccaaaacg atgagacaaa aatttgcaga
    10021 attttcacaa aacagtctca gtgtagacaa tagtattaaa gcagaagtaa gatatctttt
    10081 tgctgatacc aagtttgcag ctattaataa taactttact agctataagt atgaaattaa
    10141 tctaaatgca ccactagatg aatccaaaac agagctccca atatcgtcgc tatctgtagg
    10201 aattgatcaa aacgggctat atctttggtc agaacaacta aataaaaaag ttattccaca
    10261 attttcaaat gcaataaatg gactgggcgt agaaagtgaa atgtataggt ttctatattt
    10321 aatatctcga aataggtatg aggaatttaa acctttactt ccatattatc ttgaaaacaa
    10381 gaattggagt cctaggttaa cttatgaaga tatgattata aaaagagaag agtggcgact
    10441 agattctgtt tttttatcgg aatataaaga agattttaat aaagctttaa aagattggca
    10501 aaatcgttat aatgtcccat caatagttgg gctttctcag ggagaggcac caattattta
    10561 caatttagat aatccgttac atcttaaatt actaaaaagg ttcattatga agaaagatct
    10621 aaaacaagtt tcttttgttg aagtcccaga aattaccgaa tggcatgaat ctaaaattag
    10681 tcaattatcg ttttcttttt atgtaccata tgaatgtaat gataacaatg aaaatagtgt
    10741 atttctaaca cagaaaagaa taaaaactga taaggtgtca ttgcttcaag gactgatatc
    10801 tatcaatatt ttcccaagtt cttacttaaa ggattcactt agtgtagttc aaaagtcgat
    10861 ccaaaattta aattgtaaat acttttttat taattatttg gataaccaga gaaagagtat
    10921 tcgtttaaga gtgtggccta taaatgttgt tcttttaaaa aatattttca ttagactaga
    10981 taatttaagt gctcaaaaga tgatatatga ctatcaagta gtaaattact tgccagagta
    11041 ttctaggtat ggtggtcagt cattttataa tcaaatgctt acagcatttt atcaagacag
    11101 taaaaatgca ctttgcacag aagggatgaa tagttcagat aaatgcttag caacgattga
    11161 tagcatcatt caaattttag attttgtaac tatcaagagt gaaacttggc aacaaatcca
    11221 aggttttgat gaaaaattaa ttgataaaca tagttctatc atagaaaaat tagaaaggtt
    11281 taatagtaaa tataacagta aagttaaata tcaaatacaa gatgacttag gagattactt
    11341 aaaggaaatc aagctagagt atataaataa tccatctaag tactatagta tattgttatc
    11401 gtttattcat atgcatgtta atagatactt agcaccaagt aaaaaagaag agcgagatat
    11461 ctatttaagt atattggaat attatcgaat taaagaggat gctaagaaat atggaaaggt
    11521 tagaaagtaa aatacttttt cattcatata aaatttgtgt aagtgaatgt gagtctgcac
    11581 tgaaagatat tagtttagcg gatggtttag ctgggattag cattttttta tctaattttt
    11641 ataaatctgt tgatgaagat gcggtaaaaa ataaaattcg agaaataaat ctaagagtaa
    11701 tcaccaaagc tgtgaaagaa attaatagtc aaggaactgt tctatcctta tttggtggat
    11761 taacaggggt aggtactgca tgcatggaag caatggaata tgaagagaaa tatattacat
    11821 tactgactaa gattactaag gctgttgttg aaaaggtaaa tgttgtattt gaagatccta
    11881 atatttacac aaatttaact tttcaaattt atgatctatt taatggggca gttggaatat
    11941 cacttttttt atcaaaagta tataaaaaag gagtagatat ccctaattta ggaaaggcaa
    12001 tacattgctt aactactttt ttgataaaag tatcagtgat tgatattaag catttttctg
    12061 aatcgttatt attcttacct gctgatgaat tgccgaaaag tggcgatgca cagaaattac
    12121 tgcctaaagg cgctttatta attggagaag cgcatggttt agcaggaatt ttaggatgtt
    12181 taggtacaat ttataagatt tttccgtctt tatatttgaa aaaacacatt caaaatatat
    12241 tagaattttt gcacagaatt cgagatgata gtgtcctata tccagaatat gtgttatctt
    12301 ctaaagataa tacacctcag gtacctcatc acaagcttaa tgggggatgg tgttttggat
    12361 ctttaggaac aacgtactct attcttttaa gttctgaaag tataaggaat ggcggttggg
    12421 ctgatcaagc aaaaaaggat ttgaaattcc tctttgataa ttggaaggat gatattcgca
    12481 gggattcatt gataatgtgt catggattgg caagtcaaat atatatcgct aatgtgctga
    12541 ataaaattta tgatgattta catttagaaa aaacaattac cgaaatgata agttttactg
    12601 ttcattcagc gaactggaaa aataaatatt tattttcaga tgttgctatg tccttaaaag
    12661 ggaaaaaaag atatgaaaga ggaatacttg aaggagagtt aggtgtaagt ttagttttaa
    12721 attcagtagt ttccaatatc aaatgggatg ctgattggat atttttattt ggataggggt
    12781 ggtataaatg aaatcgcaat atttccaagc caattttcga attgcacgta agtcaaaaaa
    12841 gaatatgttg cttgccattt tattggtagt ttgcatgatt tttgctgtac tggttgtaga
    12901 gaagcaaaaa atcaacgatg gctaccgtca atggcgagac tacaatgagt ccgttcacgt
    12961 taatgcagat tatttttcta gcaatttact acggaaaaag gattacaaac aaactttcaa
    13021 taatctgaat aaacaggccg agtatttggc tggcgtacaa aatggtgaag tatttgattc
    13081 gcctcaagat tatttacaaa attccaaaaa attagtgcaa acgatgctgg cgggttatca
    13141 aaataattat cgtggtgctt caacgctgaa tgtcccaccg aaatatcagc tgcgacaaaa
    13201 attagtagtt tacgattatt tgtaccagca tcacttagca attgtcatga attctaaaga
    13261 atctagcacc tacttaatct acattttagg attagtcggc atgttcttat ttttctacgt
    13321 cttatttatt gctagtgata gttggatgat taacttatcg catccaactt tgctcaaaaa
    13381 tattccttac cagattaggg acgaagttga aggtaaattt atcatcaatc tcgctttgac
    13441 tttgcttctg ctagtgattg ggatgttagg gagttactta tttgctggct ttaaaaatgg
    13501 ctttaatagt ctgaattatc cagcagtttt gtacttcggc aaaattagcg cggttccact
    13561 gtggctttat tgtttgttgt atttaaccta tgcagttata ttagtgatgt ttgtgactag
    13621 cctggcattg ctgcttaatc aattaactca cagcgtttat ttgacaattt ttattgcggc
    13681 attggtttac agtatttcac ttttgccagg cagtattgct aaatatcttt tctttttgcc
    13741 ttcagcttat ctaaatatta gcagtgttct agatggaact gtcgcaagtc aatcaattat
    13801 tccggcaaat tgggcagtcg gtatgactat tttactagtg tggactgtcg tgctggttat
    13861 ctggttcagg catttggtta accaaggtgg tgttgaaaaa tgaaaaaaca gtatttttta
    13921 ttccagctaa aaatgttttt gactaatccc aaaaacgtcg gcctgtttgc cattaccatt
    13981 gtgtttgcac tttattttgg cttagtcagc gcaccccagc atcatgtaat tgaaaatgta
    14041 gatccatatg caattactaa agaatatcag gatgaccagg cctttttaaa ggtggctgaa
    14101 aaagaatttg cgcaggcaga taaaggtact tcggattatg atcccagcga aggtactaaa
    14161 gatgctatca ctacttatcc gaccatcatt aagtatgacc atgagcgttt aaaggcactt
    14221 aagaatcatg attggcgttt atataccaaa tatagtagca attggtatca gaaaatggat
    14281 aatttgattt gggttaaaga aaatcagaat tacatgtatc cgttggaata ttaccacaac
    14341 aataattaca aagaagacgg acactttggc tatcaaagaa catttcattt ctatgatggc
    14401 ttgcttaaga gtcaggcaaa attgaacaaa aatgttttag aagaacggac tactttacag
    14461 aggctgcagc agtcgctttc tggctggacg atgattattt taattgtgat tgtcgttttg
    14521 tttgcggcag atatgataac caatgatcaa aaataccgca cagtagtgaa gaatattcct
    14581 ctttctaaaa gaacaattct ttggctaaaa actgcggtta ttgaagtagg ggttttgttt
    14641 aactttttag ttgcttttct agtcgttacg ttgtgtactg cgccaagata tggttttggg
    14701 tcttttaatt tattaacgcc aatttatact ggacgtctgt attttaaaac gccatttgtt
    14761 taccagacat tgggacaata ttatcttggc ttcttgcttt ttgcagttgt aattaccttt
    14821 atttttatta gattgacatt gctattgtcg ctaattttta gaaatgaata tgtagctgct
    14881 attatttcta gcattttggc aatgagtgcc aaagtccttt atttctcatt ggggatgggt
    14941 tttgtttatc catttttgaa gcaattaccg atgacatatt ttacaattgg cgaaagtttg
    15001 accagcaact tatcgtatct aatggattcg ccaggctggg gttttagtga tggactcgtt
    15061 ccattactca tctttgcaat tgcaatcgag gcagtgattt ggctattttg ccagtttaga
    15121 aacttggtat tagtgaagta ggtgaaaaca tgttaaagat taataatgtt aaattagctt
    15181 ttggcaagca tgtcgttctt gatcaaatta atttagcctt tcaggcagga actattgtag
    15241 gcttagttgc gccaaatgga acgggtaagt caactctatt gaatgtgatt ttgcataatc
    15301 ttgaaccaca agcaggatat gtagaatacg atcatttacg ttaccgcagc aatcgggaga
    15361 ttatcaagct gcaccaactg atttgtgctt tccctgacca aagcgatttg gttccattca
    15421 tgagcggcag ggaccacttg aagctttatg cggatctatg gggtaattca gataaaaaag
    15481 tagatgagat cattaatcaa ttacagatgg cggactatgt agatcgacct acccatactt
    15541 attccttggg gatgaaacag cgactttgtt ttgccatggt agtagcagcc gatacgccgg
    15601 taatgttgct ggacgaagtg atgaatggac ttgatccaca aaatgtgcaa ttaatttcaa
    15661 actgtttatt aaaattaaaa aaagaaaata aactgattat catggcttca cacttgttaa
    15721 ataatctgca gtcttatgcg gatcgggtgc tttttctgaa ggcaggtaaa gtgattgaag
    15781 atcttgataa tcagcatcaa actaaacagt acctgaaaac tgaagcaaat gagcaagttg
    15841 aagctctgtt aaaagataaa aagtttacta agttgcctga taataaaatt attttgccat
    15901 tagaagataa tgatccagaa ttagatcagc ttgtgttgca aatgactaaa caaaaaattc
    15961 cgtattcaat tgggcgaatt gatttgacgg aattatttag caagttttat ggataacaaa
    16021 tagctctgca taatgcagag ctttattttg attccctaaa ttatttaata cctaattttg
    16081 ctttgatacc atcagaaaga atagctgaaa aattaagacc agcagctttt ccttcttcat
    16141 ttaagtagtt tggaatagtt agagtcttct taactacacg ttcatcgttt ttccgtttgt
    16201 attctgaaat attgacggta actaaagtag caatttcatc attttttgtt ttaggaattt
    16261 tgacatttga ttttggtaag tcttctacta atgacatagt accaattaag tcttttccca
    16321 tatcaatggc ttctgcaatt gtttttcctt gagtatcacg gtcaaggtct ggaacattta
    16381 cagtgtactt aattttagaa tcattagttg gttttataat aattggaaaa acaacgattt
    16441 tatctttttt cataaaatta attaagatgg tacacgaata aggggtcaac cccccttatt
    16501 tttatccttt aagattattt cgtttcataa tctttagcca ggtaattttg ttcatatcac
    16561 cgtgacgagg aattggctct gaatgatgac catcggtata aacatcatga ttagttccat
    16621 gacgatcaag ccaccaacca tttttcttta aaattttaag agcgtctcgc cttttaacca
    16681 tctcatttct cctttcgaat attataatac acgtatgcca tacgtgtgta aacataaatg
    16741 aaaagattat cttacttttt tagtttttat gaaaaaagac acaagatttg ttgaaatatc
    16801 ataaatatga tatataatat aaaaataagt taatcataaa taacttatac gtagcatacg
    16861 aattatggag gacatgatta tgaataataa ttctaagcgt aaggctaata agtttgacga
    16921 agattttgta gcttggatgt tagtaacaca ggcagtggta gttgctgctt gtgcatactt
    16981 agtttcaaca ggtttcttta caacgttacc agtttaaatt aaacataagt aaatcataca
    17041 taacatatga atccagtata atacgaggag aaaagaaaat gaaaattatt acttttgcag
    17101 ctatcaaagg cggtgtaggt aaaactacat tagcctataa ctatggtgaa tggttggcta
    17161 atcaaggatc acggattctt ttcatcgact tagatcatca gtctaatttg acccaaacat
    17221 atcaaattta tgataataaa tatacagtgg gaaacatttt cctaaagaat gatcaagtta
    17281 aaattcatca gattaacgaa aatattgatc tgattgcagg agatatgcac ttagacgata
    17341 ttgaagcaga cattgaaact aaagttgata aaaatatgtt gctgtacatg tggttagcag
    17401 ataattatga tactagaagt cttgatcaat atgattacat tattattgat tgtcaccctg
    17461 atttttcaat tgctaccaag aatgcagtga ttatcagtga tgatattctt agtcctatta
    17521 ctccaagcga acatggttat agtgctaagt ttaatttgga ggagcgcttt aaagaactta
    17581 aacgagaaac gattgactat agtaccagac agtcattagt agatgctaaa ctgctatttg
    17641 tcggaaatat gattaagaac aatactagat cttctcatga actactagag gttttgaaga
    17701 aggatccaag tgtcatagcc aagattccta atcgtgagct gtttaatcgt tctacgctag
    17761 ataaagtagc aattagtacg ataatgaagg ataaaacaat ggaacataaa tatggggcat
    17821 tttttagtga actaaatgat atttttgatt ccattacaaa taatgtataa atagtggata
    17881 tgttaaataa acgttaaata taagtgatgt atataggtat aagaaaggat ttttagaatg
    17941 agctttaatc caaatcaagg taaaaaattt gcggcagcat taaaagagtc aaagcctaaa
    18001 ttgaatgaac aagattctga tgtgcaagat tcaactgaag aaaatagtaa ttatattaaa
    18061 cgtgaaaaga ggaagccata tacttttagt ttaatgccaa gtgcaagaat taaactaaca
    18121 gagagtgcga aagaacatgg atataattca tcttctaatt atttaaatga tgctatttta
    18181 aatggaaaat tataacaaat agtgaatgaa ataataagca ttcttgcata agtatctcat
    18241 ctttttaact tattacttaa tgacaaaacc atcattttaa ataattttgt ttaaaatgat
    18301 ggttttttag ttgcacccga agctatatca aatttaactg tactcaaagc gtaaaaaaag
    18361 actgtgaaga tttaatggct tacttacttg aaatttttct cgaatttgta aaagattagg
    18421 caaatttttg caaaaatgag tttaactatt atatagttaa gattatctaa acttttatct
    18481 ttatttaaag ttagaatgtg ttgtaaaaat gaaggaatta aaaaatgaaa attggtgaag
    18541 cattaaaaga agaacgtata aatttaggta tgtcaaaata tcaattttca aaaggaatag
    18601 ttgataggaa attttatggc aaagtggaga aagaagaggg aacaattagt tcgaagaaat
    18661 tattattatt gctacaaaaa aatgacataa actttcaaga atttttttgt aaacttcaat
    18721 ctaaagaaaa attagtaaac ttcaatctaa agaaaaatta aatgttgaaa atctagataa
    18781 gtcaatgaga gaagcattta atagaaaaga cttgcagaaa tgtaaaagaa tttgtcagca
    18841 gattttgaaa ttgaaagatg aaaaaatttt aaaattacgc gcaatagtag caacttatta
    18901 tttagaagat aagttagact acttaaaaga tagtattaaa aaagaaatag ttagtgaaat
    18961 ttataatagt aaaaacataa ctaaaaacac tccaataatt caattgtttt ctaatgtaat
    19021 gccaatatta tcgaatgatc aattaaatat cctgatttta gaattcctga gaagatatga
    19081 aaattcaaat aaaaaaacag aaatggatag aaagaggata gctgttctat taaataatta
    19141 tttggttaca tgctatgaaa aggggataga tggggatgtc gttgataaaa caataagttg
    19201 tcttatgaat atgcaagatg tgcacttatt aatatacaaa gaagtaggta aattttattt
    19261 tgaactgatt aaaggaaata aaaccaacgc attaaaaatt aaacaggaat taaaaaattg
    19321 gaattataca aacttaacag aaaaacttaa aatataaggg ttaataatct agtgttagat
    19381 aattatttga cggagtaatt atctaacact ttttttgctt taaacgagaa agggaaggac
    19441 tataattctg ccattaatat cagtaatcaa aacatgataa ataaaaagag atgtctatag
    19501 actacaatgt ctaaattgaa aaaaaaaaga tggtataaat agcacaggta agttttagtt
    19561 aaagtaagga gcattacatg ttttggtggc agttcccagt tttaccttaa agtgcggtta
    19621 cagtcttatt gtaagtaaag aaggtgaaaa aatgtataac aaattagtgg gcttgcagaa
    19681 gatgcaagtg agaaaatcaa gcaaacgaaa caactcgttc attagtattg cttgcgtgga
    19741 taaaagtacg attagtcttt ttgcttgtcc aggtaagtaa aaaaagcatg tttcaaaata
    19801 gaaaatgtgc agtataccat taaaactaca gatgtaactt tacgttttca tttcgatgta
    19861 aatcataatg atagaatatt aattattggt aaatcgggtg ttggaaaaag tacattattg
    19921 aaaataatag atggaaacat aataccagac aaggggaaag ttgttgaatt aataaataaa
    19981 cgaatttttt taaacccttt taatgatata gcatatataa atcagacacc atatattttt
    20041 tctgcatcta ttatggaaaa tataacatta tttgataata aggtagatta tcataaagta
    20101 caaaagattt taaatgaagt aaatcttaat tccttttcaa aagaaaaact agaagatata
    20161 aaactcgaga aaaatggtat ttctgtttct ggggggcaaa aacagaaaat tgaaatagct
    20221 agagctttat tttcacataa atcattaatt ttggcagatg aaatcacagc taatttagat
    20281 aggaataatg ctaaaaaaat tagggactta ttgtttagaa tacctaatcc agttatagaa
    20341 gtagcacatc attttaacga aaatgatagg aggtatacta aagtatttag gttagatgct
    20401 gatggtagtt tgaaaagaat aaggtaggta ataataatga atgaaccttt attagaaatc
    20461 tatgatttaa aaaaatgtac ggcagaagac tgattttgga tgaaatttcc ttttctgttt
    20521 ataaaggtga gatagttgct ttagtggggc ataatggtgt tggcaaaaca acacttatga
    20581 agtgtattct aggtaccaca gggtatgata aaggaataaa aatttttgaa ggtaacaaaa
    20641 taaaaaataa acaatgtttg cgtgaaattg gaggtctaat tgaacaacct ggtatatata
    20701 attttttaac aggaatggaa aatctagaat tgttaaatta taatcacggg gctcaggatt
    20761 taaattattt actaaataaa tttaatatga aatcatacct aaataaaaaa gttgctactt
    20821 attctttagg aatccgacaa aaattaggca ttattgaggc tttcttgatg ggaaacaagt
    20881 tagtaatttt ggatgagcct ataaatgcat tagatcctat ttctgttaaa gagtttagag
    20941 aagctgttga acactttagg aataaaggtg tttcattctt aatatcaagt catataatta
    21001 gcgaaactgc aaaagttgct gataaaatcc tggtcttaaa taaatcccaa ttgacggaaa
    21061 taaaaatgaa ggataatgaa gaaaaaactc ttattataaa aacttcaaat gataataaat
    21121 tagaagcact tttacagaaa gacaatgtgg aatatagttt aagaactaat aaagtaatga
    21181 taaaatgttc ttcgtttttt caagcagggc aatatgtcac taaaataata aaagcaggta
    21241 ttgacattac ttatctagat ttgagtaaag attccttaga gaataagata ttaaagatta
    21301 tgggtaaaaa aatgattagt ttgataaaca ttgaattgaa gaaaatcagt aaaagattac
    21361 aaactaaaat cgctgcttgc atattgattt tcttctattt agcaattgta atagccacaa
    21421 aatattttca tgcatttgac agtaaatttg ctgtagaaaa ttctttttct acgctacagt
    21481 ttattcctat tgttttaata atcttcacaa cctcaagtgt aactgtcgag tatcaaagtg
    21541 gtgcaataaa aacattaatt tacaatgtta agcagagata taaaatagtt atttctaaat
    21601 ttctagcttt agtaattata aatttcttta tgtatttgat tattctaatg gcgaatatac
    21661 ttattactaa atatttattt tcagagattg catcaaagaa aatactgact tatgcttcat
    21721 tatgggtaat gggatatagt attgaaaatt tatatttaat aagtttcgca tttttactag
    21781 caataatatt ttccaatcaa gctatatcag tttcattaag tgttataagt tattttttag
    21841 tcaatttaat tgatggaagt atgttttcag caataagaaa ttataatgtt ttaaaatata
    21901 accctgttaa cctgtttaat tttaagatgc aaattgtaat gccatcattt gctgctaaaa
    21961 cttgtttatc cttaagcgaa tttggttgtt tatttgcaat ttatattttt attaacatta
    22021 ttctcagtat ttttatttta aatacaaaag atttttagta agcgtcaaat aaccaagtat
    22081 attgcaaaat acaccccagc tagatgagct gaggtgtatt tctttagata ttttatttac
    22141 atttgttttg aattcattct gtccatggca aatagacttc aagcgtctcc aaatttaaaa
    22201 catcctcatt ttggcagctt ttgaagcaga taatttagat gttttccatg ccttttggta
    22261 gtttcaatca agcttaaaat tattcccgta gacatggtcc cgctaaagct tttggaaaac
    22321 agtcaatttt tgcgtttatg ttcttaaaca cataattgcg ttccattact aagaatttaa
    22381 ctgcacattc tgcttgttgt tggacagctc caaacgacca tctaataaga ctgcataaaa
    22441 atctcctggt gatttaggtt ataattgagg gctgtgttta atttgaaact cctcaagata
    22501 tatgcttttt ctttagcaca ccaagcaaag aatctccatc gccggcttga gttctttttg
    22561 tcttagccgc tgtcttaata attttgcaag taggctaatt ttgattgtag gattcacatt
    22621 tataagcatg ttggatatga ttcaagcgtt taatttgagc tggaataaag agcagctctt
    22681 gcctgacgag ggaagagcca attgccatag acaaccgatg tctgtcggac cagaacattt
    22741 ttgttccaga taatttgtaa tgaacgtcct cggatg
//
