# emapper version: emapper-2.0.1b-2-g816e190 emapper DB: 2.0 # command: ./emapper.py -i Lactobacillus_helveticus/1.contigAnn/FFN/A00000139.ffn --translate --temp_dir Lactobacillus_helveticus/4.eggNOG_mapper --output_dir Lactobacillus_helveticus/4.eggNOG_mapper --output A00000139 --cpu 36 --keep_mapping_files -m diamond # time: Fri Jun 17 21:35:42 2022 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction taxonomic scope eggNOG OGs best eggNOG OG COG Functional cat. eggNOG free text desc. GOKNOHPG_00001 326425.lhe_0995 6e-39 166.4 Lactobacillaceae Bacteria 1TQAX@1239,3F429@33958,4HCFF@91061,COG1961@1,COG1961@2 NA|NA|NA L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed GOKNOHPG_00002 334390.LAF_0679 2.8e-25 120.6 Lactobacillaceae cylA ko:K01990,ko:K11050 ko02010,map02010 M00254,M00298 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.130 Bacteria 1V0AH@1239,3FBFC@33958,4HD15@91061,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system GOKNOHPG_00003 1033837.WANG_0698 5.1e-34 150.2 Lactobacillaceae Bacteria 1TQ93@1239,3F4RD@33958,4HDNZ@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein GOKNOHPG_00005 748671.LCRIS_00011 2.1e-20 105.5 Lactobacillaceae Bacteria 1U580@1239,29NJD@1,309JD@2,3F53B@33958,4IEZA@91061 NA|NA|NA S Bacteriocin helveticin-J GOKNOHPG_00006 525365.HMPREF0548_1406 5.5e-70 271.2 Lactobacillaceae Bacteria 1U59E@1239,29DXA@1,300V7@2,3F59A@33958,4IF0P@91061 NA|NA|NA S SLAP domain GOKNOHPG_00008 1423748.BALB01000012_gene1216 7e-217 759.6 Lactobacillaceae malZ 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 GH31 Bacteria 1TR8N@1239,3F4CE@33958,4HB1D@91061,COG1501@1,COG1501@2 NA|NA|NA G Belongs to the glycosyl hydrolase 31 family GOKNOHPG_00009 1423748.BALB01000012_gene1216 1.3e-202 712.2 Lactobacillaceae malZ 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 GH31 Bacteria 1TR8N@1239,3F4CE@33958,4HB1D@91061,COG1501@1,COG1501@2 NA|NA|NA G Belongs to the glycosyl hydrolase 31 family GOKNOHPG_00010 326425.lhe_0367 1.5e-26 124.8 Lactobacillaceae Bacteria 1U6SR@1239,2B46M@1,31WXN@2,3F8F7@33958,4IGKA@91061 NA|NA|NA GOKNOHPG_00011 405566.lhv_1784 3.9e-159 567.4 Lactobacillaceae galU 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ24@1239,3F45A@33958,4HATY@91061,COG1210@1,COG1210@2 NA|NA|NA M UTP-glucose-1-phosphate uridylyltransferase GOKNOHPG_00012 1545701.LACWKB10_1244 6.4e-49 199.9 Lactobacillaceae fba 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ01@1239,3F58Z@33958,4HD42@91061,COG0191@1,COG0191@2 NA|NA|NA G Fructose-bisphosphate aldolase class-II GOKNOHPG_00013 1545701.LACWKB10_1244 5.4e-25 120.2 Lactobacillaceae fba 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ01@1239,3F58Z@33958,4HD42@91061,COG0191@1,COG0191@2 NA|NA|NA G Fructose-bisphosphate aldolase class-II GOKNOHPG_00015 1033837.WANG_1264 7.3e-104 383.3 Lactobacillaceae Bacteria 1UZH2@1239,3F4XK@33958,4HW0D@91061,COG2452@1,COG2452@2 NA|NA|NA L Resolvase, N terminal domain GOKNOHPG_00016 1033837.WANG_1265 3e-248 864.0 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TQI8@1239,3F547@33958,4HI2X@91061,COG0675@1,COG0675@2 NA|NA|NA L TIGRFAM transposase, IS605 OrfB family GOKNOHPG_00017 405566.lhv_2006 2.6e-146 524.6 Lactobacillaceae ptp2 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1W78R@1239,3F4QQ@33958,4IEVA@91061,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family GOKNOHPG_00018 326425.lhe_0246 4.4e-172 610.5 Lactobacillaceae yvdE ko:K02529 ko00000,ko03000 Bacteria 1U6Z4@1239,3F3ZC@33958,4HC2A@91061,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor GOKNOHPG_00019 405566.lhv_2090 1.4e-240 838.6 Lactobacillaceae amtB ko:K03320 ko00000,ko02000 1.A.11 Bacteria 1TQYG@1239,3F3X1@33958,4HBGK@91061,COG0004@1,COG0004@2 NA|NA|NA P ammonium transporter GOKNOHPG_00020 748671.LCRIS_00061 1.2e-78 299.3 Firmicutes Bacteria 1VGFB@1239,2DPM9@1,332MQ@2 NA|NA|NA GOKNOHPG_00022 1033837.WANG_1845 1.3e-12 79.0 Lactobacillaceae Bacteria 1U7P1@1239,2BK3T@1,32EHA@2,3F9YU@33958,4IHKA@91061 NA|NA|NA S SLAP domain GOKNOHPG_00023 1033837.WANG_1845 3e-63 248.4 Lactobacillaceae Bacteria 1U7P1@1239,2BK3T@1,32EHA@2,3F9YU@33958,4IHKA@91061 NA|NA|NA S SLAP domain GOKNOHPG_00024 326425.lhe_0259 2.6e-92 344.7 Lactobacillaceae Bacteria 1VK2R@1239,2ED8H@1,33752@2,3F8BK@33958,4HQ99@91061 NA|NA|NA GOKNOHPG_00025 326425.lhe_0260 1.2e-22 111.7 Lactobacillaceae Bacteria 1U4M0@1239,3F8FR@33958,4IECV@91061,COG5547@1,COG5547@2 NA|NA|NA S Small integral membrane protein (DUF2273) GOKNOHPG_00026 1138822.PL11_10390 7.2e-71 273.5 Bacilli Bacteria 1V63P@1239,4IR5M@91061,COG1302@1,COG1302@2 NA|NA|NA S cog cog1302 GOKNOHPG_00027 1138822.PL11_10395 8.7e-11 72.8 Lactobacillaceae Bacteria 1VENK@1239,3F7EK@33958,4HNKV@91061,COG2261@1,COG2261@2 NA|NA|NA S Transglycosylase associated protein GOKNOHPG_00028 326425.lhe_0263 6.5e-16 89.0 Lactobacillaceae Bacteria 1U6PA@1239,2A7T7@1,30WS9@2,3F892@33958,4IGGA@91061 NA|NA|NA GOKNOHPG_00029 405566.lhv_1414 2.6e-194 684.9 Lactobacillaceae xseA 3.1.11.6 ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP4E@1239,3F4RE@33958,4HAN2@91061,COG1570@1,COG1570@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides GOKNOHPG_00030 1423748.BALB01000011_gene1162 2.9e-35 154.1 Lactobacillaceae xseB 3.1.11.6 ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1VK9I@1239,3F81K@33958,4HNRB@91061,COG1722@1,COG1722@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides GOKNOHPG_00031 326425.lhe_1334 6.8e-156 556.6 Lactobacillaceae ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 ko:K00795,ko:K02523,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061,R09248 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1TPQY@1239,3F436@33958,4HA8E@91061,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family GOKNOHPG_00032 326425.lhe_1333 2.6e-149 534.6 Lactobacillaceae rrmJ 2.1.1.226,2.1.1.227 ko:K06442 ko00000,ko01000,ko03009 Bacteria 1TPE4@1239,3F45T@33958,4HAPY@91061,COG1189@1,COG1189@2 NA|NA|NA J Ribosomal RNA large subunit methyltransferase J GOKNOHPG_00033 405566.lhv_1410 2.4e-306 1057.4 Lactobacillaceae recN GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 ko:K03631,ko:K13582 ko04112,map04112 ko00000,ko00001,ko03400 Bacteria 1TP99@1239,3F43U@33958,4H9ZR@91061,COG0497@1,COG0497@2 NA|NA|NA L May be involved in recombinational repair of damaged DNA GOKNOHPG_00034 405566.lhv_1409 1e-78 299.3 Lactobacillaceae 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 Bacteria 1V6S0@1239,3F7EV@33958,4HKKR@91061,COG4405@1,COG4405@2 NA|NA|NA S ASCH GOKNOHPG_00035 1423748.BALB01000011_gene1156 2.3e-110 404.8 Lactobacillaceae gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 ko:K00942,ko:K01591 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00050,M00051 R00332,R00965,R02090 RC00002,RC00409 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_2813,iIT341.HP0321,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193,iYO844.BSU15680 Bacteria 1TP0M@1239,3F3X9@33958,4HAYW@91061,COG0194@1,COG0194@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP GOKNOHPG_00036 1423748.BALB01000011_gene1155 9.4e-33 145.6 Lactobacillaceae rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1VK74@1239,3F81N@33958,4HNHS@91061,COG1758@1,COG1758@2 NA|NA|NA K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits GOKNOHPG_00037 405566.lhv_1406 0.0 1577.8 Lactobacillaceae priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TNYB@1239,3F3N8@33958,4H9WW@91061,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA GOKNOHPG_00038 405566.lhv_1405 1.6e-171 608.6 Lactobacillaceae fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000 iSB619.SA_RS06010 Bacteria 1TQ32@1239,3F4N7@33958,4HART@91061,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus GOKNOHPG_00039 405566.lhv_1404 1e-243 849.0 Lactobacillaceae sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 1TP3N@1239,3F45F@33958,4HBQ6@91061,COG0144@1,COG0144@2,COG0781@1,COG0781@2 NA|NA|NA J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA GOKNOHPG_00040 326425.lhe_1325 8.6e-145 519.6 Lactobacillaceae stp 3.1.3.16 ko:K20074 ko00000,ko01000,ko01009 Bacteria 1V6K5@1239,3F4UI@33958,4HCDR@91061,COG0631@1,COG0631@2 NA|NA|NA T phosphatase GOKNOHPG_00041 326425.lhe_1324 0.0 1145.6 Lactobacillaceae prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 1TP3F@1239,3F4G6@33958,4H9KD@91061,COG0515@1,COG0515@2,COG2815@1,COG2815@2 NA|NA|NA KLT serine threonine protein kinase GOKNOHPG_00042 405566.lhv_1401 3.1e-164 584.3 Lactobacillaceae rsgA 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 Bacteria 1TPSQ@1239,3F3XH@33958,4HA9W@91061,COG1162@1,COG1162@2 NA|NA|NA S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit GOKNOHPG_00043 326425.lhe_1322 1.6e-117 428.7 Lactobacillaceae rpe 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQK8@1239,3F4KX@33958,4H9RW@91061,COG0036@1,COG0036@2 NA|NA|NA G Belongs to the ribulose-phosphate 3-epimerase family GOKNOHPG_00044 405566.lhv_1399 4e-127 460.7 Lactobacillaceae thiN 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 R00619 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1VA0W@1239,3F4N8@33958,4HHS1@91061,COG1564@1,COG1564@2 NA|NA|NA H thiamine pyrophosphokinase GOKNOHPG_00045 405566.lhv_1398 5.2e-50 203.4 Lactobacillaceae Bacteria 1U65W@1239,2AE84@1,31424@2,3F756@33958,4IFVX@91061 NA|NA|NA GOKNOHPG_00046 525365.HMPREF0548_0839 2.4e-26 124.0 Lactobacillaceae rpmB GO:0003674,GO:0003735,GO:0005198 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEI2@1239,3F7ZN@33958,4HNIK@91061,COG0227@1,COG0227@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL28 family GOKNOHPG_00047 1423748.BALB01000011_gene1141 6.8e-57 226.5 Lactobacillaceae asp Bacteria 1V731@1239,3F72W@33958,4HIS4@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function GOKNOHPG_00048 326425.lhe_1317 7.6e-305 1052.4 Lactobacillaceae yloV ko:K07030 ko00000 Bacteria 1TQMX@1239,3F3X0@33958,4HBSE@91061,COG1461@1,COG1461@2 NA|NA|NA S DAK2 domain fusion protein YloV GOKNOHPG_00049 326425.lhe_1316 0.0 1299.6 Lactobacillaceae recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TQ6I@1239,3F3JW@33958,4HAWN@91061,COG1200@1,COG1200@2 NA|NA|NA L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) GOKNOHPG_00050 405566.lhv_1393 1e-179 636.0 Lactobacillaceae plsX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPXS@1239,3F4N9@33958,4HA0R@91061,COG0416@1,COG0416@2 NA|NA|NA I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA GOKNOHPG_00051 326425.lhe_1314 3.4e-36 157.1 Lactobacillaceae acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 1VEE3@1239,3F7F4@33958,4HNQ0@91061,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis GOKNOHPG_00052 405566.lhv_1391 2.6e-194 684.5 Lactobacillaceae oppD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP6E@1239,3F41T@33958,4HA4E@91061,COG0444@1,COG0444@2 NA|NA|NA P Belongs to the ABC transporter superfamily GOKNOHPG_00053 326425.lhe_1312 5.9e-180 636.7 Lactobacillaceae oppF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02032,ko:K10823,ko:K12372,ko:K13892 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00324,M00348,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.11,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1V36J@1239,3F4GM@33958,4H9YB@91061,COG4608@1,COG4608@2 NA|NA|NA P Belongs to the ABC transporter superfamily GOKNOHPG_00054 1033837.WANG_0407 1e-173 615.9 Lactobacillaceae oppB ko:K02033,ko:K02034,ko:K13894 ko02010,ko02024,map02010,map02024 M00239,M00349 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 Bacteria 1TP1S@1239,3FCCU@33958,4HATR@91061,COG0601@1,COG0601@2 NA|NA|NA P ABC transporter permease GOKNOHPG_00055 326425.lhe_1310 1.7e-144 518.8 Lactobacillaceae oppC ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP4R@1239,3FCB7@33958,4HDIR@91061,COG1173@1,COG1173@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component GOKNOHPG_00056 405566.lhv_2929 0.0 1120.1 Lactobacillaceae oppA ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1TQ0N@1239,3F3KW@33958,4HARF@91061,COG0747@1,COG0747@2 NA|NA|NA E ABC transporter substrate-binding protein GOKNOHPG_00057 1423748.BALB01000011_gene1131 1.1e-29 135.6 Lactobacillaceae oppA ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1TQ0N@1239,3F3KW@33958,4HARF@91061,COG0747@1,COG0747@2 NA|NA|NA E ABC transporter substrate-binding protein GOKNOHPG_00058 326425.lhe_1308 1.6e-28 131.7 Lactobacillaceae oppA ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1TQ0N@1239,3F3KW@33958,4HARF@91061,COG0747@1,COG0747@2 NA|NA|NA E ABC transporter substrate-binding protein GOKNOHPG_00059 326425.lhe_1308 3.7e-101 374.4 Lactobacillaceae oppA ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1TQ0N@1239,3F3KW@33958,4HARF@91061,COG0747@1,COG0747@2 NA|NA|NA E ABC transporter substrate-binding protein GOKNOHPG_00060 326425.lhe_1308 2.2e-72 278.1 Lactobacillaceae oppA ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1TQ0N@1239,3F3KW@33958,4HARF@91061,COG0747@1,COG0747@2 NA|NA|NA E ABC transporter substrate-binding protein GOKNOHPG_00061 326425.lhe_1307 1.9e-124 451.8 Lactobacillaceae rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 1TPGC@1239,3F564@33958,4HAWU@91061,COG0571@1,COG0571@2 NA|NA|NA J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism GOKNOHPG_00062 405566.lhv_1379 0.0 1446.0 Lactobacillaceae smc ko:K03529 ko00000,ko03036 Bacteria 1TPJV@1239,3F478@33958,4HB89@91061,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning GOKNOHPG_00063 326425.lhe_1305 3.7e-166 591.3 Lactobacillaceae ftsY ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 1TPRI@1239,3F3YC@33958,4HA6A@91061,COG0552@1,COG0552@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) GOKNOHPG_00064 326425.lhe_1304 5.5e-288 996.1 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase GOKNOHPG_00065 1423748.BALB01000030_gene1903 2.6e-18 97.1 Lactobacillaceae Bacteria 1U68Z@1239,29P84@1,30A66@2,3F7C1@33958,4IG04@91061 NA|NA|NA GOKNOHPG_00066 326425.lhe_1302 3.5e-258 897.1 Lactobacillaceae yfnA ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3FCAJ@33958,4HA32@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid GOKNOHPG_00067 326425.lhe_1301 3.2e-56 224.2 Lactobacillaceae ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 ko:K09787 ko00000 Bacteria 1VEGP@1239,3F7FG@33958,4HKK6@91061,COG2739@1,COG2739@2 NA|NA|NA S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein GOKNOHPG_00068 326425.lhe_1300 2.2e-228 798.1 Lactobacillaceae ffh GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 1TP06@1239,3F40R@33958,4H9T4@91061,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY GOKNOHPG_00069 1033837.WANG_0417 4.5e-45 186.8 Lactobacillaceae rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VA0X@1239,3F6VV@33958,4HKNN@91061,COG0228@1,COG0228@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS16 family GOKNOHPG_00070 326425.lhe_1298 5.8e-94 350.1 Lactobacillaceae rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 ko:K02860 ko00000,ko03009 Bacteria 1V6HD@1239,3F74P@33958,4HH3H@91061,COG0806@1,COG0806@2 NA|NA|NA J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes GOKNOHPG_00071 405566.lhv_1369 8.5e-136 489.6 Lactobacillaceae trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1TPBV@1239,3F3NP@33958,4HBFV@91061,COG0336@1,COG0336@2 NA|NA|NA J Belongs to the RNA methyltransferase TrmD family GOKNOHPG_00072 1423748.BALB01000030_gene1896 1.1e-56 225.7 Lactobacillaceae rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6FT@1239,3F6K4@33958,4HIK3@91061,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site GOKNOHPG_00073 405566.lhv_1366 9.7e-120 436.4 Lactobacillaceae ung2 3.2.2.27 ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V4M9@1239,3F4GW@33958,4HHJN@91061,COG1573@1,COG1573@2 NA|NA|NA L Uracil-DNA glycosylase GOKNOHPG_00074 326425.lhe_1294 1.2e-146 525.8 Lactobacillaceae Bacteria 1V4VT@1239,3F4P8@33958,4HXCK@91061,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase family GOKNOHPG_00075 405566.lhv_1364 1.3e-111 409.1 Lactobacillaceae lexA 3.4.21.88 ko:K01356 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 1TQ3H@1239,3F3JG@33958,4HBHA@91061,COG1974@1,COG1974@2 NA|NA|NA K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair GOKNOHPG_00076 1423748.BALB01000030_gene1892 2.5e-37 161.0 Lactobacillaceae ynzC Bacteria 1VEKJ@1239,3F87S@33958,4HNIB@91061,COG4224@1,COG4224@2 NA|NA|NA S UPF0291 protein GOKNOHPG_00077 405566.lhv_1362 4.2e-30 136.7 Lactobacillaceae yneF ko:K09976 ko00000 Bacteria 1VEJC@1239,3F809@33958,4HKMJ@91061,COG3763@1,COG3763@2 NA|NA|NA S Uncharacterised protein family (UPF0154) GOKNOHPG_00078 326425.lhe_0514 6.3e-85 320.1 Lactobacillaceae XK27_08435 ko:K03710 ko00000,ko03000 Bacteria 1UYYY@1239,3F5F4@33958,4HGI6@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA GOKNOHPG_00080 1423758.BN55_05375 2.8e-27 127.5 Lactobacillaceae Bacteria 1U6PM@1239,2BU0G@1,32P91@2,3F89C@33958,4IGGK@91061 NA|NA|NA GOKNOHPG_00081 97137.C821_01321 1.9e-21 109.4 Lactobacillaceae Bacteria 1U85T@1239,2A094@1,30NCE@2,3FAK0@33958,4II3B@91061 NA|NA|NA GOKNOHPG_00082 1423767.BALU01000004_gene1377 3.3e-76 291.2 Lactobacillaceae ko:K07133 ko00000 Bacteria 1TP7X@1239,3F51K@33958,4HCSJ@91061,COG1373@1,COG1373@2 NA|NA|NA S cog cog1373 GOKNOHPG_00083 525365.HMPREF0548_1721 2e-60 238.4 Lactobacillaceae ko:K07133 ko00000 Bacteria 1TP7X@1239,3F51K@33958,4HCSJ@91061,COG1373@1,COG1373@2 NA|NA|NA S cog cog1373 GOKNOHPG_00084 1423807.BACO01000083_gene2430 1.5e-194 685.3 Lactobacillaceae ko:K18481,ko:K18640 M00670 ko00000,ko00002,ko02000,ko04812 3.A.1.27.4,3.A.1.27.5 Bacteria 1V76M@1239,3F499@33958,4IU5K@91061,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein GOKNOHPG_00085 1423748.BALB01000011_gene1165 1.1e-18 98.2 Lactobacillaceae nusB ko:K03625 ko00000,ko03009,ko03021 Bacteria 1VA9B@1239,3F7KW@33958,4HKMU@91061,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons GOKNOHPG_00086 1423748.BALB01000011_gene1164 4.9e-151 540.4 Lactobacillaceae folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1P@1239,3F46A@33958,4H9Q6@91061,COG0190@1,COG0190@2 NA|NA|NA F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate GOKNOHPG_00087 1423748.BALB01000010_gene1078 3.5e-71 274.2 Lactobacillaceae yeaL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1V7JN@1239,3F68U@33958,4HINS@91061,COG2707@1,COG2707@2 NA|NA|NA S Protein of unknown function (DUF441) GOKNOHPG_00088 1423748.BALB01000010_gene1079 1.8e-10 71.2 Lactobacillaceae Bacteria 1U6Q0@1239,29PJU@1,30AHZ@2,3F8A1@33958,4IGGY@91061 NA|NA|NA GOKNOHPG_00089 264199.stu0649 2.9e-24 117.1 Bacilli msrR Bacteria 1TSWQ@1239,4HE66@91061,COG1316@1,COG1316@2 NA|NA|NA K Transcriptional regulator GOKNOHPG_00090 264199.stu1444 6.8e-113 413.3 Firmicutes Bacteria 1TQ93@1239,COG3464@1,COG3464@2 NA|NA|NA L Transposase GOKNOHPG_00091 405566.lhv_1254 3.9e-159 567.4 Lactobacillaceae degV Bacteria 1TRM7@1239,3F40W@33958,4HBIR@91061,COG1307@1,COG1307@2 NA|NA|NA S EDD domain protein, DegV family GOKNOHPG_00092 326425.lhe_1135 1.3e-64 252.3 Lactobacillaceae Bacteria 1U6A0@1239,29P8Y@1,30A72@2,3F7ER@33958,4IG18@91061 NA|NA|NA GOKNOHPG_00093 405566.lhv_1255 0.0 1109.7 Lactobacillaceae FbpA ko:K12341 ko03070,map03070 ko00000,ko00001,ko02044 1.B.40.1.1 Bacteria 1TQ8A@1239,3F3PS@33958,4H9UF@91061,COG1293@1,COG1293@2 NA|NA|NA K Fibronectin-binding protein GOKNOHPG_00094 405566.lhv_1256 0.0 2049.2 Lactobacillaceae carB1 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPID@1239,3F3MD@33958,4HAEY@91061,COG0458@1,COG0458@2 NA|NA|NA F Carbamoyl-phosphate synthase GOKNOHPG_00095 405566.lhv_1257 1.1e-197 695.7 Lactobacillaceae carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383,iYO844.BSU15510 Bacteria 1TQ8N@1239,3F43R@33958,4H9Z0@91061,COG0505@1,COG0505@2 NA|NA|NA F Carbamoyl-phosphate synthetase glutamine chain GOKNOHPG_00096 405566.lhv_1258 9.3e-156 556.2 Lactobacillaceae rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1TPCM@1239,3F3P6@33958,4HBG2@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil GOKNOHPG_00097 405566.lhv_1259 9.5e-80 302.8 Lactobacillaceae lspA 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1VA9R@1239,3F66R@33958,4HIR4@91061,COG0597@1,COG0597@2 NA|NA|NA MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins GOKNOHPG_00098 326425.lhe_1141 0.0 1086.6 Lactobacillaceae fhs 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP6N@1239,3F3U6@33958,4HA2X@91061,COG2759@1,COG2759@2 NA|NA|NA F Belongs to the formate--tetrahydrofolate ligase family GOKNOHPG_00099 1423748.BALB01000007_gene894 2.8e-34 151.0 Lactobacillaceae Bacteria 1U6UZ@1239,29PP8@1,30AME@2,3F8IU@33958,4IGNU@91061 NA|NA|NA GOKNOHPG_00100 1423748.BALB01000007_gene893 4.2e-81 307.4 Lactobacillaceae cpdA Bacteria 1UQCQ@1239,3F483@33958,4HG8Z@91061,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase GOKNOHPG_00101 1423748.BALB01000007_gene893 5.1e-69 266.9 Lactobacillaceae cpdA Bacteria 1UQCQ@1239,3F483@33958,4HG8Z@91061,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase GOKNOHPG_00102 405566.lhv_1263 4e-217 760.4 Lactobacillaceae rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016423,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 ko:K07444,ko:K12297 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1TP0X@1239,3F3NZ@33958,4HBKY@91061,COG0116@1,COG0116@2 NA|NA|NA L Belongs to the methyltransferase superfamily GOKNOHPG_00103 405566.lhv_1264 3e-69 267.7 Lactobacillaceae gpsB ko:K04074 ko00000,ko03036 Bacteria 1VEQ4@1239,3F6VZ@33958,4HNP1@91061,COG3599@1,COG3599@2 NA|NA|NA D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation GOKNOHPG_00104 405566.lhv_1265 7.2e-106 389.8 Lactobacillaceae ypsA Bacteria 1V6SM@1239,3F4MR@33958,4HJGM@91061,COG4474@1,COG4474@2 NA|NA|NA S Belongs to the UPF0398 family GOKNOHPG_00105 326425.lhe_1146 1e-116 426.0 Lactobacillaceae recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03700 ko00000,ko03400 Bacteria 1V3S4@1239,3F4DG@33958,4HGZ7@91061,COG3331@1,COG3331@2 NA|NA|NA L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation GOKNOHPG_00106 326425.lhe_1147 0.0 1322.4 Lactobacillaceae ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366,ko:K12555,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1TPM5@1239,3F424@33958,4H9SA@91061,COG0744@1,COG0744@2 NA|NA|NA M penicillin-binding protein 1A GOKNOHPG_00107 326425.lhe_1148 3.9e-113 414.1 Lactobacillaceae nth 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TRAK@1239,3F42U@33958,4HATD@91061,COG0177@1,COG0177@2 NA|NA|NA L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate GOKNOHPG_00108 405566.lhv_1269 7.4e-115 419.9 Lactobacillaceae dnaD ko:K02086 ko00000 Bacteria 1V283@1239,3F4FF@33958,4HFP3@91061,COG3935@1,COG3935@2 NA|NA|NA L DnaD domain protein GOKNOHPG_00109 326425.lhe_1150 2.6e-260 904.0 Lactobacillaceae asnS GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP38@1239,3F4EK@33958,4H9YH@91061,COG0017@1,COG0017@2 NA|NA|NA J Asparaginyl-tRNA synthetase GOKNOHPG_00110 326425.lhe_1151 2.4e-89 334.7 Lactobacillaceae ypmB Bacteria 1VA2H@1239,3F4MM@33958,4HNMM@91061,COG5353@1,COG5353@2 NA|NA|NA S Protein conserved in bacteria GOKNOHPG_00111 405566.lhv_1272 0.0 1808.9 Lactobacillaceae dinG GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.6.4.12 ko:K02342,ko:K03722 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TQHQ@1239,3F4KA@33958,4HB2Y@91061,COG0847@1,COG0847@2,COG1199@1,COG1199@2 NA|NA|NA L helicase involved in DNA repair and perhaps also replication GOKNOHPG_00112 326425.lhe_1153 0.0 2318.9 Lactobacillaceae addA 3.6.4.12 ko:K16898 ko00000,ko01000,ko03400 Bacteria 1TQ35@1239,3F3Z0@33958,4HA64@91061,COG1074@1,COG1074@2 NA|NA|NA L ATP-dependent helicase nuclease subunit A GOKNOHPG_00113 405566.lhv_1274 0.0 2261.9 Lactobacillaceae rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.3,3.6.4.12 ko:K01153,ko:K16899 ko00000,ko01000,ko02048,ko03400 Bacteria 1TQJW@1239,3FCA9@33958,4HK67@91061,COG3857@1,COG3857@2 NA|NA|NA L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity GOKNOHPG_00114 326425.lhe_1155 7.6e-166 589.7 Lactobacillaceae mvk 1.1.1.88,2.3.3.10,2.7.1.36 ko:K00054,ko:K00869,ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,ko04146,map00072,map00280,map00650,map00900,map01100,map01110,map01130,map04146 M00088,M00095 R01978,R02081,R02245 RC00002,RC00004,RC00017,RC00503,RC00644 ko00000,ko00001,ko00002,ko01000 Bacteria 1UFCB@1239,3FBNI@33958,4HG49@91061,COG1577@1,COG1577@2 NA|NA|NA I GHMP kinases N terminal domain GOKNOHPG_00115 326425.lhe_1156 8.3e-179 632.9 Lactobacillaceae mvaD 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQXR@1239,3F4B5@33958,4HAM6@91061,COG3407@1,COG3407@2 NA|NA|NA I diphosphomevalonate decarboxylase GOKNOHPG_00116 405566.lhv_1277 4.2e-203 713.8 Lactobacillaceae mvaK2 2.7.1.36,2.7.1.43,2.7.4.2 ko:K00869,ko:K00938,ko:K16190 ko00040,ko00053,ko00520,ko00900,ko01100,ko01110,ko01130,ko04146,map00040,map00053,map00520,map00900,map01100,map01110,map01130,map04146 M00014,M00095 R01476,R02245,R03245 RC00002,RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPKP@1239,3F3RZ@33958,4HC93@91061,COG1577@1,COG1577@2 NA|NA|NA I phosphomevalonate kinase GOKNOHPG_00117 405566.lhv_1278 4.1e-184 650.6 Lactobacillaceae fni 1.1.1.88,5.3.3.2 ko:K00054,ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123,R02081 RC00004,RC00455,RC00644 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQZ3@1239,3F3UY@33958,4HAMV@91061,COG1304@1,COG1304@2 NA|NA|NA C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) GOKNOHPG_00118 405566.lhv_1279 1.2e-260 905.2 Lactobacillaceae rsmF 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 1TPGQ@1239,3F492@33958,4HCHQ@91061,COG0144@1,COG0144@2 NA|NA|NA J NOL1 NOP2 sun family protein GOKNOHPG_00119 326425.lhe_1160 1.8e-173 615.1 Lactobacillaceae Bacteria 1VNCY@1239,2EPHD@1,33H40@2,3F495@33958,4HYY7@91061 NA|NA|NA GOKNOHPG_00120 405566.lhv_1281 1.1e-138 499.2 Lactobacillaceae Bacteria 1VQQ8@1239,2E39Q@1,32Y99@2,3F4UX@33958,4HRY1@91061 NA|NA|NA GOKNOHPG_00121 405566.lhv_1282 5.2e-104 383.6 Lactobacillaceae lepB 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1V7H9@1239,3F4SM@33958,4HIQ4@91061,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family GOKNOHPG_00122 1423748.BALB01000007_gene870 5e-27 126.3 Lactobacillaceae Bacteria 1U6MC@1239,29PI4@1,30AG9@2,3F858@33958,4IGE7@91061 NA|NA|NA GOKNOHPG_00123 405566.lhv_1284 1.6e-45 188.3 Lactobacillaceae rarA ko:K07478 ko00000 Bacteria 1TPVV@1239,3F3NB@33958,4HAIS@91061,COG2256@1,COG2256@2 NA|NA|NA L recombination factor protein RarA GOKNOHPG_00125 1033837.WANG_0617 6.3e-97 360.1 Lactobacillaceae Bacteria 1U5RF@1239,2A1GN@1,30PQ9@2,3F6DA@33958,4IFFK@91061 NA|NA|NA GOKNOHPG_00126 1423748.BALB01000007_gene843 1.7e-88 332.0 Lactobacillaceae Bacteria 1UI90@1239,2DVJ8@1,33W59@2,3F5JD@33958,4HD3X@91061 NA|NA|NA S Peptidase family M23 GOKNOHPG_00127 1423748.BALB01000032_gene1943 6.6e-29 132.9 Lactobacillaceae Bacteria 1W58V@1239,2DEEV@1,2ZMQ9@2,3F7PV@33958,4I00W@91061 NA|NA|NA S Transposase C of IS166 homeodomain GOKNOHPG_00128 1423748.BALB01000032_gene1942 2.9e-54 217.6 Lactobacillaceae ko:K07484 ko00000 Bacteria 1VAJD@1239,3F7E1@33958,4HKCG@91061,COG3436@1,COG3436@2 NA|NA|NA L PFAM IS66 Orf2 family protein GOKNOHPG_00129 326425.lhe_0391 8.1e-47 193.0 Lactobacillaceae Bacteria 1U644@1239,2BZTJ@1,30A2T@2,3F6ZQ@33958,4IFTP@91061 NA|NA|NA GOKNOHPG_00130 1423748.BALB01000003_gene480 2.4e-62 245.0 Lactobacillaceae Bacteria 1TPAA@1239,3F755@33958,4HC6H@91061,COG5421@1,COG5421@2 NA|NA|NA L Transposase DDE domain GOKNOHPG_00131 405566.lhv_0193 1.6e-122 445.7 Lactobacillaceae gepA ko:K18830 ko00000,ko02048,ko03000 Bacteria 1UK2I@1239,3F4EH@33958,4ITGB@91061,COG2944@1,COG2944@2,COG3600@1,COG3600@2 NA|NA|NA K Protein of unknown function (DUF4065) GOKNOHPG_00132 405566.lhv_0192 0.0 1107.0 Lactobacillaceae yjbQ ko:K03455,ko:K03499 ko00000,ko02000 2.A.37,2.A.38.1,2.A.38.4 Bacteria 1TS32@1239,3F4AZ@33958,4H9Q5@91061,COG0475@1,COG0475@2,COG0569@1,COG0569@2 NA|NA|NA P TrkA C-terminal domain protein GOKNOHPG_00133 326425.lhe_0190 1.3e-207 728.8 Lactobacillaceae atl 3.2.1.96,3.5.1.28 ko:K01447,ko:K13714 R04112 RC00064,RC00141 ko00000,ko01000 GH73 Bacteria 1V3MY@1239,3F4BU@33958,4HBWG@91061,COG5632@1,COG5632@2 NA|NA|NA M N-acetylmuramoyl-L-alanine amidase GOKNOHPG_00134 326425.lhe_0189 1.6e-222 778.5 Lactobacillaceae ko:K02395 ko00000,ko02035 Bacteria 1TVPT@1239,3F4I7@33958,4HC0X@91061,COG1705@1,COG1705@2 NA|NA|NA NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase GOKNOHPG_00135 326425.lhe_0188 2.1e-98 365.5 Lactobacillaceae Bacteria 1U6DR@1239,29PBT@1,30AA0@2,3F7P3@33958,4IG5G@91061 NA|NA|NA GOKNOHPG_00136 748671.LCRIS_00174 1.1e-49 203.0 Lactobacillaceae Bacteria 1U6KG@1239,3F83H@33958,4IGD9@91061,COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation GOKNOHPG_00137 1423748.BALB01000008_gene917 7.3e-39 167.5 Lactobacillaceae Bacteria 1U8EN@1239,29QPJ@1,30BP9@2,3FAWE@33958,4IICH@91061 NA|NA|NA GOKNOHPG_00139 1423754.BALY01000052_gene1836 1.2e-98 367.5 Lactobacillaceae Bacteria 1U5FB@1239,2DKJ8@1,309P7@2,3F5UP@33958,4IF6X@91061 NA|NA|NA S SLAP domain GOKNOHPG_00140 1423748.BALB01000008_gene913 5.2e-38 163.3 Bacilli Bacteria 1VKCM@1239,2DR42@1,33A2M@2,4HRAS@91061 NA|NA|NA S Protein of unknown function (DUF2922) GOKNOHPG_00141 405566.lhv_0182 3.3e-10 69.7 Lactobacillaceae Bacteria 1U6IH@1239,2AQKB@1,31FT9@2,3F7ZB@33958,4IGAU@91061 NA|NA|NA GOKNOHPG_00143 1423748.BALB01000006_gene744 1.3e-70 272.3 Lactobacillaceae Bacteria 1U5KK@1239,29NU4@1,309S8@2,3F65J@33958,4IFBH@91061 NA|NA|NA GOKNOHPG_00144 1423748.BALB01000006_gene745 0.0 1283.5 Lactobacillaceae kup GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 ko:K03549 ko00000,ko02000 2.A.72 Bacteria 1TRUQ@1239,3F4CU@33958,4HA8Z@91061,COG3158@1,COG3158@2 NA|NA|NA P Transport of potassium into the cell GOKNOHPG_00145 326425.lhe_0179 0.0 1291.2 Lactobacillaceae pepO 3.4.24.71 ko:K01415,ko:K07386 ko00000,ko01000,ko01002,ko04147 Bacteria 1TQTA@1239,3F4CX@33958,4HDSF@91061,COG3590@1,COG3590@2 NA|NA|NA O Peptidase family M13 GOKNOHPG_00146 405566.lhv_0173 4.1e-223 780.4 Lactobacillaceae yttB Bacteria 1TPJ6@1239,3F4F9@33958,4HAGJ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GOKNOHPG_00147 326425.lhe_0177 5.9e-227 793.1 Lactobacillaceae XK27_04775 ko:K09155 ko00000 Bacteria 1TRD5@1239,3F45M@33958,4HAAW@91061,COG2461@1,COG2461@2 NA|NA|NA S PAS domain GOKNOHPG_00148 326425.lhe_0176 3.3e-98 364.4 Lactobacillaceae ko:K02612,ko:K09155 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1V9YV@1239,3F7D5@33958,4HKC6@91061,COG2151@1,COG2151@2,COG2461@1,COG2461@2 NA|NA|NA S Iron-sulfur cluster assembly protein GOKNOHPG_00149 1423748.BALB01000006_gene752 9.6e-140 502.7 Lactobacillaceae nrdG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0031250,GO:0032991,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 1.97.1.4 ko:K04068 R04710 ko00000,ko01000 iE2348C_1286.E2348C_4563 Bacteria 1V1HG@1239,3F46H@33958,4HGJ9@91061,COG0602@1,COG0602@2 NA|NA|NA O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine GOKNOHPG_00150 326425.lhe_0174 0.0 1507.7 Lactobacillaceae nrdD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019001,GO:0019103,GO:0019438,GO:0019637,GO:0019692,GO:0030554,GO:0031250,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032556,GO:0032558,GO:0032559,GO:0032560,GO:0032564,GO:0032567,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0046872,GO:0046914,GO:0051065,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_4713,iPC815.YPO3454 Bacteria 1TR9K@1239,3F435@33958,4HBIY@91061,COG1328@1,COG1328@2 NA|NA|NA F Ribonucleoside-triphosphate reductase GOKNOHPG_00151 1423758.BN55_02795 6.2e-46 190.3 Lactobacillaceae 3.6.3.6 ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 3.A.3.3 Bacteria 1TPF5@1239,3F55J@33958,4HVA4@91061,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus GOKNOHPG_00152 1423758.BN55_02795 1.4e-21 108.6 Lactobacillaceae 3.6.3.6 ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 3.A.3.3 Bacteria 1TPF5@1239,3F55J@33958,4HVA4@91061,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus GOKNOHPG_00153 1423758.BN55_02795 2.8e-161 575.1 Lactobacillaceae 3.6.3.6 ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 3.A.3.3 Bacteria 1TPF5@1239,3F55J@33958,4HVA4@91061,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus GOKNOHPG_00154 326425.lhe_0172 2.3e-253 880.9 Lactobacillaceae yxbA 6.3.1.12 ko:K17810 ko00000,ko01000 Bacteria 1TQPN@1239,3F3S7@33958,4HAB0@91061,COG3919@1,COG3919@2 NA|NA|NA S ATP-grasp enzyme GOKNOHPG_00155 405566.lhv_0164 0.0 1328.2 Lactobacillaceae asnB 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 1TRPB@1239,3FB65@33958,4HA44@91061,COG0367@1,COG0367@2 NA|NA|NA E Asparagine synthase GOKNOHPG_00156 405566.lhv_0163 5.4e-272 943.0 Lactobacillaceae Bacteria 1VMH1@1239,2EQYH@1,33II5@2,3F5E7@33958,4HUIK@91061 NA|NA|NA S Calcineurin-like phosphoesterase GOKNOHPG_00157 326425.lhe_0169 8.1e-82 309.7 Lactobacillaceae Bacteria 1U5KG@1239,2CCK1@1,309S4@2,3F64Y@33958,4IFBA@91061 NA|NA|NA GOKNOHPG_00158 405566.lhv_0161 2.3e-107 394.8 Lactobacillaceae tag 3.2.2.20 ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1UYWG@1239,3F5KA@33958,4HGWW@91061,COG2818@1,COG2818@2 NA|NA|NA L glycosylase GOKNOHPG_00159 405566.lhv_0160 1.4e-147 528.9 Lactobacillaceae phnE 3.6.1.63 ko:K02042,ko:K06162 ko00440,ko02010,map00440,map02010 M00223 R10186 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 Bacteria 1V15B@1239,3F4TN@33958,4IQWU@91061,COG3639@1,COG3639@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component GOKNOHPG_00160 326425.lhe_0166 6.5e-129 466.8 Lactobacillaceae phnE 3.6.1.63 ko:K02042,ko:K06162 ko00440,ko02010,map00440,map02010 M00223 R10186 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 Bacteria 1TR1S@1239,3F58M@33958,4HBT8@91061,COG3639@1,COG3639@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component GOKNOHPG_00161 326425.lhe_0165 5.2e-139 500.4 Lactobacillaceae phnC GO:0006810,GO:0008150,GO:0015716,GO:0051179,GO:0051234,GO:0071702 3.6.3.28 ko:K02041 ko02010,map02010 M00223 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 Bacteria 1TQG6@1239,3F3SJ@33958,4HC3N@91061,COG3638@1,COG3638@2 NA|NA|NA P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system GOKNOHPG_00162 1033837.WANG_1706 3.3e-148 531.2 Lactobacillaceae phnD ko:K02044 ko02010,map02010 M00223 ko00000,ko00001,ko00002,ko02000 3.A.1.9 Bacteria 1TR0H@1239,3F3KK@33958,4HBJQ@91061,COG3221@1,COG3221@2 NA|NA|NA P Phosphonate ABC transporter GOKNOHPG_00163 326425.lhe_0163 3.6e-85 320.9 Lactobacillaceae uspA ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1VEJR@1239,3F4Z0@33958,4HNHG@91061,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein GOKNOHPG_00164 326425.lhe_0162 1.8e-147 528.5 Lactobacillaceae ptp3 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1V851@1239,3F55V@33958,4HJB2@91061,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family GOKNOHPG_00165 511437.Lbuc_2396 2.2e-91 341.7 Lactobacillaceae Bacteria 1TRSF@1239,3F3WY@33958,4HTRR@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family GOKNOHPG_00166 203120.LEUM_0858 1.8e-22 111.3 Leuconostocaceae Bacteria 1TR53@1239,4AXCH@81850,4HB8Y@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase GOKNOHPG_00167 1423748.BALB01000009_gene1024 9e-59 233.0 Lactobacillaceae Bacteria 1TSH6@1239,3F5HS@33958,4HEX8@91061,COG3385@1,COG3385@2 NA|NA|NA L PFAM transposase, IS4 family protein GOKNOHPG_00168 1423754.BALY01000006_gene1369 9.4e-10 68.2 Lactobacillaceae ko:K07483 ko00000 Bacteria 1V4FD@1239,3FBFG@33958,4IQ19@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain GOKNOHPG_00169 1423754.BALY01000036_gene554 1.7e-164 585.5 Lactobacillaceae ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0409 Bacteria 1TQ22@1239,3F48Z@33958,4HA7K@91061,COG0282@1,COG0282@2 NA|NA|NA F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction GOKNOHPG_00170 405566.lhv_2002 0.0 1130.5 Lactobacillaceae malL 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13,GH31 Bacteria 1UY2T@1239,3FC10@33958,4HBRE@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain GOKNOHPG_00171 326425.lhe_0249 0.0 1178.7 Lactobacillaceae nplT 3.2.1.133,3.2.1.135,3.2.1.54 ko:K01208 ko00500,ko01100,map00500,map01100 R02112,R03122,R11262 ko00000,ko00001,ko01000 GH13 Bacteria 1TNZ0@1239,3F41N@33958,4HB67@91061,COG0366@1,COG0366@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family GOKNOHPG_00172 405566.lhv_2000 0.0 1540.0 Lactobacillaceae map2 2.4.1.8 ko:K00691 ko00500,ko01100,map00500,map01100 R01555 RC00049 ko00000,ko00001,ko01000 GH65 Bacteria 1TQMB@1239,3F3PG@33958,4HAVB@91061,COG1554@1,COG1554@2 NA|NA|NA G hydrolase, family 65, central catalytic GOKNOHPG_00173 405566.lhv_1999 4.8e-117 427.2 Lactobacillaceae pgmB GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008801,GO:0009058,GO:0009292,GO:0009294,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016853,GO:0016866,GO:0016868,GO:0019203,GO:0030312,GO:0033554,GO:0034637,GO:0040007,GO:0042221,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046351,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0071704,GO:0071944,GO:1901576 2.4.1.64,3.1.3.12,3.2.1.28,5.4.2.6 ko:K01087,ko:K01194,ko:K01838,ko:K05342 ko00500,ko01100,map00500,map01100 R00010,R02727,R02728,R02778,R11310 RC00017,RC00049,RC00408 ko00000,ko00001,ko00537,ko01000 GH37,GH65 Bacteria 1UY8N@1239,3F4ST@33958,4HF3K@91061,COG0637@1,COG0637@2 NA|NA|NA S beta-phosphoglucomutase GOKNOHPG_00174 1423748.BALB01000024_gene1747 2.5e-203 714.5 Lactobacillaceae msmX ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko02000 3.A.1.1 Bacteria 1TP2M@1239,3FC3D@33958,4HAMQ@91061,COG3842@1,COG3842@2 NA|NA|NA P Belongs to the ABC transporter superfamily GOKNOHPG_00175 405566.lhv_1997 5.2e-210 736.9 Lactobacillaceae malE ko:K15770 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 Bacteria 1TPU9@1239,3F50T@33958,4HAK6@91061,COG2182@1,COG2182@2 NA|NA|NA G Bacterial extracellular solute-binding protein GOKNOHPG_00176 326425.lhe_0254 5.3e-248 863.2 Lactobacillaceae malF ko:K02025,ko:K02026,ko:K15771 ko02010,map02010 M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2 Bacteria 1TR2A@1239,3F4J1@33958,4HB8H@91061,COG1175@1,COG1175@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component GOKNOHPG_00177 326425.lhe_0255 5.3e-153 547.0 Lactobacillaceae malG ko:K15772 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 Bacteria 1TRB7@1239,3F4NP@33958,4HC5K@91061,COG3833@1,COG3833@2 NA|NA|NA P ABC transporter permease GOKNOHPG_00178 1423754.BALY01000024_gene999 2e-83 315.1 Lactobacillaceae ymdB Bacteria 1TPCU@1239,3F6GV@33958,4HIHC@91061,COG2110@1,COG2110@2 NA|NA|NA S Macro domain protein GOKNOHPG_00179 525365.HMPREF0548_1488 1.5e-101 375.9 Lactobacillaceae Bacteria 1UVUA@1239,3F7YF@33958,4IGAD@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins GOKNOHPG_00181 1403946.Q615_SPAC00113G0012 4.8e-08 65.5 Streptococcus anginosus group Bacteria 1TVT2@1239,42DXW@671232,4I45P@91061,COG4932@1,COG4932@2 NA|NA|NA M MucBP domain GOKNOHPG_00182 1423807.BACO01000088_gene2513 4e-108 399.1 Lactobacillaceae Bacteria 1UHY6@1239,3FBS3@33958,4ISAK@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein GOKNOHPG_00183 349123.Lreu23DRAFT_3295 3.5e-85 321.6 Lactobacillaceae Bacteria 1TSH6@1239,3F5HS@33958,4HEX8@91061,COG3385@1,COG3385@2 NA|NA|NA L PFAM transposase, IS4 family protein GOKNOHPG_00184 1423732.BALS01000119_gene9 3.2e-95 354.4 Lactobacillaceae cysE 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR42@1239,3F63E@33958,4HAKS@91061,COG1045@1,COG1045@2 NA|NA|NA E Bacterial transferase hexapeptide (six repeats) GOKNOHPG_00185 797515.HMPREF9103_03168 1.2e-214 752.3 Lactobacillaceae metC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.4.1.1,4.4.1.2,4.4.1.8 ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00782,R01001,R01283,R01286,R02408,R04941 RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC7@1239,3F3Y2@33958,4HAFQ@91061,COG0626@1,COG0626@2 NA|NA|NA E cystathionine GOKNOHPG_00186 1423732.BALS01000119_gene7 1.4e-167 595.5 Lactobacillaceae mccA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042127,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0065007,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.134,2.5.1.47 ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00609 R00897,R03601,R04859,R10305 RC00020,RC00069,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS02385 Bacteria 1TP30@1239,3F4VD@33958,4HAMU@91061,COG0031@1,COG0031@2 NA|NA|NA E Belongs to the cysteine synthase cystathionine beta- synthase family GOKNOHPG_00188 511437.Lbuc_2396 6.8e-93 346.7 Lactobacillaceae Bacteria 1TRSF@1239,3F3WY@33958,4HTRR@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family GOKNOHPG_00189 416870.llmg_0666 8.4e-224 782.7 Lactococcus oxlT ko:K08177 ko00000,ko02000 2.A.1.11 Bacteria 1TPR9@1239,1YCA4@1357,4HB93@91061,COG2223@1,COG2223@2 NA|NA|NA P Major Facilitator Superfamily GOKNOHPG_00190 203123.OEOE_0347 8.4e-102 376.3 Leuconostocaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,4AXYS@81850,4HC8M@91061,COG2801@1,COG2801@2 NA|NA|NA L HTH-like domain GOKNOHPG_00191 1123359.AUIQ01000085_gene536 1.6e-74 285.4 Enterococcaceae ko:K07483 ko00000 Bacteria 1V35U@1239,4B6SW@81852,4HHRN@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain GOKNOHPG_00192 1423807.BACO01000098_gene2536 1.2e-40 173.3 Lactobacillaceae 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 1TP7S@1239,3F50Q@33958,4HB5A@91061,COG0610@1,COG0610@2 NA|NA|NA V Subunit R is required for both nuclease and ATPase activities, but not for modification GOKNOHPG_00193 1033837.WANG_1781 7.5e-152 543.1 Lactobacillaceae nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 1.4.3.16,2.4.2.19 ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481,R03348 RC00006,RC02566,RC02877 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1988,iHN637.CLJU_RS12010,iLJ478.TM1645 Bacteria 1TPQC@1239,3F58H@33958,4HB46@91061,COG0157@1,COG0157@2 NA|NA|NA H Quinolinate phosphoribosyl transferase, C-terminal domain GOKNOHPG_00194 1033837.WANG_1782 2.9e-213 747.7 Lactobacillaceae yceI ko:K08369 ko00000,ko02000 2.A.1 Bacteria 1TQM0@1239,3F3SE@33958,4HATA@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GOKNOHPG_00195 1154757.Q5C_01445 1.4e-44 185.3 Leuconostocaceae Bacteria 1U3F5@1239,29MJA@1,308H4@2,4AXYE@81850,4ID7T@91061 NA|NA|NA GOKNOHPG_00196 907931.AEIZ01000029_gene1538 8.7e-41 172.6 Leuconostocaceae tcdA2 ko:K03497,ko:K13582 ko04112,map04112 ko00000,ko00001,ko03000,ko03036,ko04812 Bacteria 1UI5C@1239,4AWZS@81850,4ISE9@91061,COG0497@1,COG0497@2 NA|NA|NA L Plasmid recombination enzyme GOKNOHPG_00197 1045854.WKK_06862 1.6e-122 445.7 Leuconostocaceae ko:K07498 ko00000 Bacteria 1V1XJ@1239,4AXJP@81850,4HD1W@91061,COG5527@1,COG5527@2 NA|NA|NA L Initiator Replication protein GOKNOHPG_00198 1045854.WKK_06862 8.7e-61 239.6 Leuconostocaceae ko:K07498 ko00000 Bacteria 1V1XJ@1239,4AXJP@81850,4HD1W@91061,COG5527@1,COG5527@2 NA|NA|NA L Initiator Replication protein GOKNOHPG_00199 1045854.WKK_06867 8e-34 150.6 Leuconostocaceae WQ51_02910 Bacteria 1VNC1@1239,2EHT6@1,33BIW@2,4AYXY@81850,4HRJ5@91061 NA|NA|NA K HTH DNA binding domain GOKNOHPG_00200 1450694.BTS2_2962 5.5e-87 328.2 Bacillus 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1TPHR@1239,1ZGWR@1386,4HFEJ@91061,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain GOKNOHPG_00201 326425.lhe_0269 1.7e-254 884.8 Lactobacillaceae ykgC GO:0000302,GO:0000305,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0019725,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901530,GO:1901700,GO:1990748 1.16.1.1,1.8.1.7 ko:K00383,ko:K00520,ko:K21739 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1TP1W@1239,3FC6T@33958,4HBZF@91061,COG1249@1,COG1249@2 NA|NA|NA C Pyridine nucleotide-disulfide oxidoreductase GOKNOHPG_00202 326425.lhe_1558 3.2e-88 331.3 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1UZ6K@1239,3F5A4@33958,4HCYU@91061,COG3694@1,COG3694@2 NA|NA|NA S ABC-2 family transporter protein GOKNOHPG_00204 405566.lhv_0020 1.6e-13 80.9 Lactobacillaceae isp2 Bacteria 1TQ93@1239,3F4RD@33958,4HDNZ@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein GOKNOHPG_00205 405566.lhv_1941 6.6e-154 550.1 Lactobacillaceae isp2 Bacteria 1TQ93@1239,3F4RD@33958,4HDNZ@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein GOKNOHPG_00206 326425.lhe_1550 6.2e-82 310.1 Lactobacillaceae racA ko:K11686,ko:K13640,ko:K18997 ko00000,ko03000,ko03036 Bacteria 1V7Z4@1239,3F6W4@33958,4HPH8@91061,COG0789@1,COG0789@2 NA|NA|NA K Domain of unknown function (DUF1836) GOKNOHPG_00207 585524.HMPREF0493_0570 1.2e-152 545.8 Lactobacillaceae yitS Bacteria 1TSKD@1239,3FBEP@33958,4HC4E@91061,COG1307@1,COG1307@2 NA|NA|NA S EDD domain protein, DegV family GOKNOHPG_00210 324831.LGAS_1663 2e-22 114.0 Lactobacillaceae dnaX 2.4.99.16,2.7.7.7 ko:K02343,ko:K02519,ko:K07114,ko:K14192,ko:K14194,ko:K14201,ko:K16147,ko:K20276 ko00230,ko00240,ko00500,ko01100,ko02024,ko03030,ko03430,ko03440,ko05150,map00230,map00240,map00500,map01100,map02024,map03030,map03430,map03440,map05150 M00260 R00375,R00376,R00377,R00378,R09994 RC02795 ko00000,ko00001,ko00002,ko01000,ko02000,ko03012,ko03029,ko03032,ko03400 1.A.13.2.2,1.A.13.2.3 GH13 Bacteria 1UHY6@1239,3FBS3@33958,4ISAK@91061,COG3115@1,COG3115@2,COG4932@1,COG4932@2 NA|NA|NA M domain protein GOKNOHPG_00211 324831.LGAS_1663 2.3e-81 309.7 Lactobacillaceae dnaX 2.4.99.16,2.7.7.7 ko:K02343,ko:K02519,ko:K07114,ko:K14192,ko:K14194,ko:K14201,ko:K16147,ko:K20276 ko00230,ko00240,ko00500,ko01100,ko02024,ko03030,ko03430,ko03440,ko05150,map00230,map00240,map00500,map01100,map02024,map03030,map03430,map03440,map05150 M00260 R00375,R00376,R00377,R00378,R09994 RC02795 ko00000,ko00001,ko00002,ko01000,ko02000,ko03012,ko03029,ko03032,ko03400 1.A.13.2.2,1.A.13.2.3 GH13 Bacteria 1UHY6@1239,3FBS3@33958,4ISAK@91061,COG3115@1,COG3115@2,COG4932@1,COG4932@2 NA|NA|NA M domain protein GOKNOHPG_00212 1423748.BALB01000005_gene697 1.6e-135 488.8 Lactobacillaceae mdcD 4.1.1.87 ko:K13932,ko:K13933 ko00000,ko01000 Bacteria 1TSPB@1239,3F4MQ@33958,4HAM5@91061,COG4799@1,COG4799@2 NA|NA|NA I Malonate decarboxylase gamma subunit (MdcE) GOKNOHPG_00213 1423748.BALB01000005_gene698 1.1e-113 416.0 Lactobacillaceae mdcG 2.7.7.66 ko:K13934 R10706 ko00000,ko01000 Bacteria 1VE6C@1239,28INI@1,2Z8NU@2,3F57N@33958,4HNAY@91061 NA|NA|NA H Phosphoribosyl-dephospho-CoA transferase MdcG GOKNOHPG_00214 1423748.BALB01000005_gene699 9.1e-139 499.6 Lactobacillaceae yisY 1.11.1.10 ko:K00433 ko00000,ko01000 Bacteria 1VH04@1239,3FBUH@33958,4IT4E@91061,COG0596@1,COG0596@2 NA|NA|NA S Alpha/beta hydrolase family GOKNOHPG_00215 405566.lhv_1673 2.9e-148 531.2 Lactobacillaceae citG 2.4.2.52,2.7.7.61 ko:K05966,ko:K13927,ko:K13930 ko02020,map02020 R09675,R10706 RC00049,RC00063 ko00000,ko00001,ko01000 Bacteria 1TQGQ@1239,3F4SU@33958,4HGCS@91061,COG1767@1,COG1767@2 NA|NA|NA H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase GOKNOHPG_00216 405566.lhv_1672 6.5e-41 172.9 Lactobacillaceae Bacteria 1U624@1239,2AE03@1,313SN@2,3F6UV@33958,4IFR4@91061 NA|NA|NA GOKNOHPG_00217 1423748.BALB01000005_gene705 1e-136 492.7 Lactobacillaceae glpF ko:K02440 ko00000,ko02000 1.A.8.1,1.A.8.2 Bacteria 1TP4T@1239,3F4J6@33958,4HAWP@91061,COG0580@1,COG0580@2 NA|NA|NA U Belongs to the MIP aquaporin (TC 1.A.8) family GOKNOHPG_00218 326425.lhe_1542 1.4e-122 445.7 Lactobacillaceae mgtC ko:K07507 ko00000,ko02000 9.B.20 Bacteria 1V409@1239,3FB84@33958,4HC2G@91061,COG1285@1,COG1285@2 NA|NA|NA S MgtC family GOKNOHPG_00219 405566.lhv_1668 2.5e-161 574.7 Lactobacillaceae rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 Bacteria 1TSM6@1239,3F50K@33958,4HA7M@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil GOKNOHPG_00220 405566.lhv_1667 0.0 1361.3 Lactobacillaceae pbp2A 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366,ko:K12555,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1TPM5@1239,3F49Q@33958,4H9SA@91061,COG0744@1,COG0744@2 NA|NA|NA M penicillin-binding protein GOKNOHPG_00221 405566.lhv_1666 9.4e-56 222.6 Lactobacillaceae yheA Bacteria 1VASS@1239,3F822@33958,4HKKC@91061,COG3679@1,COG3679@2 NA|NA|NA S Belongs to the UPF0342 family GOKNOHPG_00222 405566.lhv_1665 2.2e-229 801.2 Lactobacillaceae yhaO ko:K03547 ko00000,ko03400 Bacteria 1TWMI@1239,3F3PX@33958,4HCA0@91061,COG0420@1,COG0420@2 NA|NA|NA L Ser Thr phosphatase family protein GOKNOHPG_00223 405566.lhv_1664 0.0 1167.5 Lactobacillaceae Bacteria 1TQP3@1239,3F3PF@33958,4HBCA@91061,COG0419@1,COG0419@2,COG4717@1,COG4717@2 NA|NA|NA L AAA domain GOKNOHPG_00224 326425.lhe_1535 4.2e-186 657.1 Lactobacillaceae cbf ko:K03698 ko00000,ko01000,ko03019 Bacteria 1TPIU@1239,3F4SF@33958,4HB1M@91061,COG3481@1,COG3481@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. GOKNOHPG_00225 326425.lhe_1534 2.3e-50 204.5 Lactobacillaceae ko:K09155 ko00000 Bacteria 1TRD5@1239,3F45M@33958,4HAAW@91061,COG2461@1,COG2461@2 NA|NA|NA S PAS domain GOKNOHPG_00226 1423748.BALB01000005_gene719 7.3e-153 546.6 Lactobacillaceae prsA 5.2.1.8 ko:K02597,ko:K07533 ko00000,ko01000,ko03110 Bacteria 1TX3R@1239,3FB3Y@33958,4HC85@91061,COG0760@1,COG0760@2 NA|NA|NA M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins GOKNOHPG_00227 326425.lhe_1532 4e-27 127.5 Lactobacillaceae Bacteria 1U65N@1239,29P5R@1,30A3W@2,3F74E@33958,4IFVH@91061 NA|NA|NA GOKNOHPG_00228 1423748.BALB01000005_gene721 3.1e-80 304.3 Lactobacillaceae hit ko:K02503 ko00000,ko04147 Bacteria 1V9ZJ@1239,3FCD7@33958,4HJ19@91061,COG0537@1,COG0537@2 NA|NA|NA FG Scavenger mRNA decapping enzyme C-term binding GOKNOHPG_00229 405566.lhv_1658 1.2e-41 175.6 Lactobacillaceae Bacteria 1U5QE@1239,3F7U8@33958,4IG85@91061,COG3549@1,COG3549@2 NA|NA|NA S Plasmid maintenance system killer GOKNOHPG_00230 405566.lhv_1657 8.4e-54 216.1 Lactobacillaceae higA ko:K18831,ko:K21498 ko00000,ko02048,ko03000 Bacteria 1U65V@1239,3F752@33958,4IFVU@91061,COG3093@1,COG3093@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins GOKNOHPG_00231 326425.lhe_1528 8.8e-136 489.6 Lactobacillaceae ecsA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQIH@1239,3F444@33958,4HA2B@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter, ATP-binding protein GOKNOHPG_00232 326425.lhe_1527 2.2e-213 748.0 Lactobacillaceae ecsB ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1VG@1239,3F4HH@33958,4HG1K@91061,COG4473@1,COG4473@2 NA|NA|NA U ABC transporter GOKNOHPG_00233 405566.lhv_1653 9.1e-121 439.5 Lactobacillaceae trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33 ko:K02493,ko:K03439 R10806 RC00003,RC03279 ko00000,ko01000,ko03012,ko03016 Bacteria 1TQCA@1239,3F3QM@33958,4HC08@91061,COG0220@1,COG0220@2 NA|NA|NA J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA GOKNOHPG_00234 326425.lhe_1525 1.8e-53 214.9 Lactobacillaceae ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 2.7.1.180,5.3.4.1 ko:K01829,ko:K03671,ko:K03734,ko:K06196 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko02000,ko03110 5.A.1.2 Bacteria 1VAS6@1239,3F72K@33958,4HKGM@91061,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin GOKNOHPG_00235 326425.lhe_1524 4.1e-121 440.7 Lactobacillaceae pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890,ko:K06878 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1V7QA@1239,3FBJ0@33958,4HJBD@91061,COG0073@1,COG0073@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily GOKNOHPG_00236 326425.lhe_1523 8.4e-259 899.0 Firmicutes Bacteria 1V4H2@1239,29PCB@1,30AAJ@2 NA|NA|NA GOKNOHPG_00237 405566.lhv_1151 1.9e-217 761.5 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TRNY@1239,3F55P@33958,4HBKP@91061,COG0675@1,COG0675@2 NA|NA|NA L transposase, IS605 OrfB family GOKNOHPG_00238 405566.lhv_1636 4.8e-254 883.2 Lactobacillaceae mpl GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464 6.3.2.4,6.3.2.45,6.3.2.8 ko:K01921,ko:K01924,ko:K02558 ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502 R01150,R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iSDY_1059.SDY_4251 Bacteria 1TQ5H@1239,3F49J@33958,4HAR4@91061,COG0773@1,COG0773@2 NA|NA|NA M Belongs to the MurCDEF family GOKNOHPG_00239 326425.lhe_1516 2.3e-176 624.8 Lactobacillaceae Bacteria 1U5FS@1239,29NRF@1,309PE@2,3F5V8@33958,4IF75@91061 NA|NA|NA S SLAP domain GOKNOHPG_00240 405566.lhv_1633 1.4e-289 1001.5 Lactobacillaceae Bacteria 1U6PC@1239,3F557@33958,4HDA6@91061,COG0308@1,COG0308@2 NA|NA|NA M Peptidase family M1 domain GOKNOHPG_00241 326425.lhe_1514 2.9e-195 687.6 Lactobacillaceae Bacteria 1U53C@1239,29NJD@1,309H9@2,3F4BP@33958,4IEUN@91061 NA|NA|NA S Bacteriocin helveticin-J GOKNOHPG_00242 405566.lhv_1631 4.3e-52 210.3 Lactobacillaceae ko:K07473 ko00000,ko02048 Bacteria 1VGJW@1239,3F6PK@33958,4HR7A@91061,COG3077@1,COG3077@2 NA|NA|NA L RelB antitoxin GOKNOHPG_00243 326425.lhe_1511 4.8e-141 507.3 Lactobacillaceae qmcA GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 Bacteria 1TPXU@1239,3F4HV@33958,4HGRC@91061,COG0330@1,COG0330@2 NA|NA|NA O prohibitin homologues GOKNOHPG_00244 405566.lhv_0268 3.6e-73 280.8 Lactobacillaceae isp2 Bacteria 1TQ93@1239,3F4RD@33958,4HDNZ@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein GOKNOHPG_00247 1545701.LACWKB10_1145 1.4e-153 549.3 Lactobacillaceae Bacteria 1TPE1@1239,3F3NJ@33958,4HA65@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family GOKNOHPG_00249 1423767.BALU01000006_gene809 1.9e-30 138.7 Firmicutes Bacteria 1VHH1@1239,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins GOKNOHPG_00250 1423767.BALU01000006_gene808 2.8e-15 87.4 Lactobacillaceae Bacteria 1U6Y9@1239,2DKSW@1,30APK@2,3F8Q3@33958,4IGSF@91061 NA|NA|NA K Helix-turn-helix XRE-family like proteins GOKNOHPG_00251 1423767.BALU01000006_gene800 2.4e-33 148.3 Lactobacillaceae Bacteria 1UPK8@1239,3F8S8@33958,4IV6I@91061,COG1846@1,COG1846@2 NA|NA|NA K Helix-turn-helix domain GOKNOHPG_00253 12348.Q37943_BPLLH 1.1e-24 119.4 Siphoviridae Viruses 4QEM3@10239,4QMFP@10699,4QUJ5@28883,4QZD2@35237 NA|NA|NA S Domain of unknown function (DUF771) GOKNOHPG_00257 1122147.AUEH01000046_gene2902 4.1e-14 84.3 Bacilli Bacteria 1UHSZ@1239,4HE2T@91061,COG2856@1,COG2856@2 NA|NA|NA E Pfam:DUF955 GOKNOHPG_00258 1260356.D920_00008 2.4e-30 139.8 Enterococcaceae Bacteria 1TQN4@1239,4B3Q0@81852,4IUW3@91061,COG4227@1,COG4227@2 NA|NA|NA L Psort location Cytoplasmic, score GOKNOHPG_00260 1423790.BN53_05380 3.8e-130 472.6 Lactobacillaceae topA2 5.99.1.2 ko:K03169 ko00000,ko01000,ko03032 Bacteria 1TPJD@1239,3F4W6@33958,4HAZV@91061,COG0550@1,COG0550@2 NA|NA|NA L This gene contains a nucleotide ambiguity which may be the result of a sequencing error GOKNOHPG_00261 575606.HMPREF0525_00357 9.9e-25 120.6 Lactobacillaceae ko:K07052 ko00000 Bacteria 1VFRX@1239,3F4Q0@33958,4HRQQ@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity GOKNOHPG_00265 883103.HMPREF9703_01034 1.7e-22 114.4 Bacilli spaB ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Bacteria 1TSSF@1239,2C4IS@1,2Z81U@2,4HC39@91061 NA|NA|NA S Lantibiotic dehydratase, C terminus GOKNOHPG_00266 1196322.A370_05564 9.4e-13 81.6 Clostridiaceae spaC2 ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Bacteria 1V13V@1239,24KSM@186801,36K0Y@31979,COG4403@1,COG4403@2 NA|NA|NA V PFAM Lanthionine synthetase GOKNOHPG_00267 1545701.LACWKB10_0646 2.6e-107 395.6 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1UZZX@1239,28MJI@1,2ZAW0@2,3F5KU@33958,4HCUA@91061 NA|NA|NA GOKNOHPG_00268 1423748.BALB01000005_gene732 1.3e-139 503.1 Lactobacillaceae Bacteria 1TT1Z@1239,28MM7@1,2ZAX4@2,3F45B@33958,4HDYX@91061 NA|NA|NA GOKNOHPG_00269 1545701.LACWKB10_0648 3.7e-101 374.8 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQA2@1239,3FC3N@33958,4HEU0@91061,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities GOKNOHPG_00270 1423754.BALY01000020_gene765 5.8e-23 114.0 Lactobacillaceae Bacteria 1VCA6@1239,3F7MJ@33958,4HPP0@91061,COG1598@1,COG1598@2 NA|NA|NA S HicB_like antitoxin of bacterial toxin-antitoxin system GOKNOHPG_00271 411460.RUMTOR_02081 1.6e-11 74.7 Clostridia hicA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 ko:K07339 ko00000,ko01000,ko02048 Bacteria 1UK3R@1239,25FIH@186801,COG1724@1,COG1724@2 NA|NA|NA N HicA toxin of bacterial toxin-antitoxin, GOKNOHPG_00273 46256.BBIK01000007_gene1246 2e-98 365.5 Leuconostocaceae ko:K03496 ko00000,ko03036,ko04812 Bacteria 1V6Q6@1239,4AWNS@81850,4HINH@91061,COG1192@1,COG1192@2 NA|NA|NA D VirC1 protein GOKNOHPG_00275 272621.LBA0125 3e-13 80.9 Lactobacillaceae Bacteria 1UFUT@1239,29NJE@1,30GE4@2,3F51E@33958,4IEZ0@91061 NA|NA|NA K Helix-turn-helix XRE-family like proteins GOKNOHPG_00276 97137.C821_00266 9.7e-26 123.6 Lactobacillaceae Bacteria 1U5FX@1239,29NJE@1,31AUJ@2,3F5VD@33958,4IF77@91061 NA|NA|NA K Helix-turn-helix XRE-family like proteins GOKNOHPG_00277 170187.SP_1342 2.4e-30 139.0 Streptococcus pneumoniae ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1V08F@1239,1WUH5@1313,4HTAU@91061,COG1132@1,COG1132@2 NA|NA|NA P ABC transporter ATP-binding GOKNOHPG_00278 1121105.ATXL01000018_gene1568 1.8e-45 190.7 Enterococcaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TP4J@1239,4B1FK@81852,4HBGH@91061,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system GOKNOHPG_00279 405566.lhv_1732 1e-167 595.9 Lactobacillaceae psaA ko:K02077 M00244 ko00000,ko00002,ko02000 3.A.1.15 Bacteria 1V110@1239,3FC74@33958,4HE71@91061,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family GOKNOHPG_00282 1423748.BALB01000034_gene1966 1.6e-216 758.4 Lactobacillaceae metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCV@1239,3F3T0@33958,4HB33@91061,COG0192@1,COG0192@2 NA|NA|NA H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme GOKNOHPG_00283 326425.lhe_1591 2.3e-257 894.4 Lactobacillaceae qacA Bacteria 1VSW8@1239,3F4AW@33958,4HUQC@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GOKNOHPG_00284 1423748.BALB01000034_gene1968 1e-147 529.6 Lactobacillaceae hepT 2.5.1.30,2.5.1.90 ko:K00805,ko:K02523 ko00900,ko01110,map00900,map01110 R09247,R09248 RC00279 ko00000,ko00001,ko01000,ko01006 Bacteria 1TR0U@1239,3F4GC@33958,4H9RH@91061,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family GOKNOHPG_00285 405566.lhv_1727 1.3e-119 435.6 Lactobacillaceae 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1VF2U@1239,3F5CM@33958,4HNXR@91061,COG0671@1,COG0671@2 NA|NA|NA I Acid phosphatase homologues GOKNOHPG_00286 405566.lhv_1726 0.0 1678.3 Lactobacillaceae leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TP0Y@1239,3F46M@33958,4HAG1@91061,COG0495@1,COG0495@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family GOKNOHPG_00287 405566.lhv_1725 2.9e-296 1023.8 Lactobacillaceae ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03328,ko:K06409 ko00000,ko02000 2.A.66.2,2.A.66.2.14 Bacteria 1TNYX@1239,3F404@33958,4H9RY@91061,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein GOKNOHPG_00288 405566.lhv_0612 5.3e-127 460.3 Lactobacillaceae rpiA GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,2.7.1.15,5.3.1.6 ko:K00851,ko:K00852,ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01051,R01056,R01737,R02750 RC00002,RC00017,RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria 1V1DB@1239,3F43N@33958,4HFQ7@91061,COG0120@1,COG0120@2 NA|NA|NA G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate GOKNOHPG_00289 326425.lhe_0602 1.9e-164 585.1 Lactobacillaceae rbsK 2.7.1.15 ko:K00852 ko00030,map00030 R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TQRC@1239,3F3S5@33958,4HA87@91061,COG0524@1,COG0524@2 NA|NA|NA H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway GOKNOHPG_00290 1423748.BALB01000004_gene555 5.5e-160 570.1 Lactobacillaceae 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSNU@1239,3F3JH@33958,4H9TY@91061,COG1085@1,COG1085@2 NA|NA|NA C Domain of unknown function (DUF4931) GOKNOHPG_00291 405566.lhv_0605 7.6e-236 822.8 Lactobacillaceae ko:K02027,ko:K05813 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 Bacteria 1UNFN@1239,3FBF0@33958,4HCSA@91061,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein GOKNOHPG_00292 272621.LBA1455 1.1e-11 75.5 Lactobacillaceae Bacteria 1U7FT@1239,29Q45@1,30B2V@2,3F9JX@33958,4IHBV@91061 NA|NA|NA S SLAP domain GOKNOHPG_00293 1423754.BALY01000001_gene1682 8.2e-82 309.7 Lactobacillaceae Bacteria 1U7FT@1239,29Q45@1,30B2V@2,3F9JX@33958,4IHBV@91061 NA|NA|NA S SLAP domain GOKNOHPG_00294 525365.HMPREF0548_0610 2.6e-63 248.1 Lactobacillaceae Bacteria 1V6G9@1239,2CJHH@1,32SA1@2,3F5FF@33958,4HIZ6@91061 NA|NA|NA S Protein of unknown function (DUF2974) GOKNOHPG_00295 1033837.WANG_1054 3.6e-74 284.3 Lactobacillaceae Bacteria 1V6G9@1239,2CJHH@1,32SA1@2,3F5FF@33958,4HIZ6@91061 NA|NA|NA S Protein of unknown function (DUF2974) GOKNOHPG_00296 326425.lhe_0607 7.5e-107 393.3 Lactobacillaceae glnP GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K02029,ko:K10002,ko:K10040 ko02010,ko02020,map02010,map02020 M00228,M00230,M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.19,3.A.1.3.4 Bacteria 1UJM4@1239,3F3WJ@33958,4HBAS@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease GOKNOHPG_00297 405566.lhv_0600 3e-108 397.9 Lactobacillaceae gluC GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K10006,ko:K10040 ko02010,map02010 M00228,M00233 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.9 Bacteria 1TQ5K@1239,3F3XW@33958,4HFBH@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease GOKNOHPG_00298 326425.lhe_0609 1.8e-150 538.5 Lactobacillaceae glnH ko:K10039 ko02010,map02010 M00228 ko00000,ko00001,ko00002,ko02000 3.A.1.3 Bacteria 1TT11@1239,3F4GG@33958,4HAHV@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter substrate-binding protein GOKNOHPG_00299 405566.lhv_0598 1.8e-133 481.9 Lactobacillaceae glnQ 3.6.3.21 ko:K02028,ko:K10041 ko02010,map02010 M00228,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein GOKNOHPG_00300 405566.lhv_0597 9.9e-67 259.2 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TRNY@1239,3F55P@33958,4HBKP@91061,COG0675@1,COG0675@2 NA|NA|NA L transposase, IS605 OrfB family GOKNOHPG_00301 1033837.WANG_0039 1.6e-37 161.8 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TRNY@1239,3F55P@33958,4HBKP@91061,COG0675@1,COG0675@2 NA|NA|NA L transposase, IS605 OrfB family GOKNOHPG_00302 748671.LCRIS_00113 1.4e-10 72.0 Lactobacillaceae Bacteria 1U6HK@1239,29PF3@1,30AD9@2,3F7XT@33958,4IG9W@91061 NA|NA|NA GOKNOHPG_00304 405566.lhv_0587 1.7e-35 154.8 Lactobacillaceae Bacteria 1U538@1239,29NJ9@1,309H6@2,3F4AG@33958,4IEUK@91061 NA|NA|NA GOKNOHPG_00305 405566.lhv_0586 1.9e-308 1064.3 Lactobacillaceae ybiT GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896 ko:K06158 ko00000,ko03012 Bacteria 1TPW0@1239,3F3ZJ@33958,4HATH@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein GOKNOHPG_00306 326425.lhe_0619 9.6e-208 729.2 Lactobacillaceae pepA Bacteria 1TNZT@1239,3F55I@33958,4H9SM@91061,COG1363@1,COG1363@2 NA|NA|NA E M42 glutamyl aminopeptidase GOKNOHPG_00307 326425.lhe_0620 1.1e-36 159.1 Lactobacillaceae mdtG GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085 ko:K08161 ko00000,ko02000 2.A.1.2.20 Bacteria 1TRDJ@1239,3FCA7@33958,4H9UE@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GOKNOHPG_00308 326425.lhe_0620 1.3e-120 439.1 Lactobacillaceae mdtG GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085 ko:K08161 ko00000,ko02000 2.A.1.2.20 Bacteria 1TRDJ@1239,3FCA7@33958,4H9UE@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GOKNOHPG_00309 405566.lhv_0583 8e-258 896.0 Lactobacillaceae emrY Bacteria 1VSW8@1239,3F4AW@33958,4HUQC@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GOKNOHPG_00310 326425.lhe_0622 1.4e-90 339.0 Lactobacillaceae pyrR 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000,ko03000 Bacteria 1V3GV@1239,3F4MT@33958,4HGYE@91061,COG2065@1,COG2065@2 NA|NA|NA F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant GOKNOHPG_00311 405566.lhv_0581 5.2e-240 836.6 Lactobacillaceae pyrP ko:K02824,ko:K16169 ko00000,ko02000 2.A.40.1.1,2.A.40.1.2,2.A.40.3.1 iLJ478.TM0819 Bacteria 1TQKX@1239,3F3UJ@33958,4HAEU@91061,COG2233@1,COG2233@2 NA|NA|NA F Permease GOKNOHPG_00312 405566.lhv_1190 1.1e-47 195.7 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3FCFA@33958,4HC8M@91061,COG2801@1,COG2801@2 NA|NA|NA L COG2963 Transposase and inactivated derivatives GOKNOHPG_00313 405566.lhv_1190 3.3e-37 160.6 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3FCFA@33958,4HC8M@91061,COG2801@1,COG2801@2 NA|NA|NA L COG2963 Transposase and inactivated derivatives GOKNOHPG_00314 1423748.BALB01000004_gene528 4.6e-76 290.4 Lactobacillaceae 2.3.1.128 ko:K03789 ko00000,ko01000,ko03009 Bacteria 1VEW7@1239,3FCFM@33958,4HQMJ@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain GOKNOHPG_00315 891391.LAC30SC_02835 1.6e-171 608.6 Lactobacillaceae 4.2.1.53 ko:K10254 ko00000,ko01000 Bacteria 1TQZ6@1239,3F3QX@33958,4HAYH@91061,COG4716@1,COG4716@2 NA|NA|NA S Myosin-crossreactive antigen GOKNOHPG_00316 1423748.BALB01000004_gene527 1.8e-40 171.4 Lactobacillaceae 4.2.1.53 ko:K10254 ko00000,ko01000 Bacteria 1TQZ6@1239,3F3QX@33958,4HAYH@91061,COG4716@1,COG4716@2 NA|NA|NA S Myosin-crossreactive antigen GOKNOHPG_00317 1033837.WANG_1116 9.1e-92 342.8 Lactobacillaceae yxdD Bacteria 1VGCX@1239,3FC4I@33958,4HH8V@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family GOKNOHPG_00318 1033837.WANG_1117 1.6e-242 845.1 Lactobacillaceae emrY Bacteria 1VSW8@1239,3F4AW@33958,4HUQC@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GOKNOHPG_00323 1033837.WANG_1118 6e-96 356.7 Lactobacillaceae MA20_25245 Bacteria 1VJPU@1239,3F5MH@33958,4HG6J@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain GOKNOHPG_00324 405566.lhv_0577 9.6e-29 132.1 Lactobacillaceae cspA ko:K03704 ko00000,ko03000 Bacteria 1VEE0@1239,3F7FW@33958,4HNJC@91061,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein GOKNOHPG_00325 1033837.WANG_1127 9.4e-141 506.1 Lactobacillaceae tnp2 Bacteria 1TQ93@1239,3F4RB@33958,4HC0Q@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM Transposase, IS204 IS1001 IS1096 IS1165 GOKNOHPG_00327 405566.lhv_0563 2.5e-253 880.9 Lactobacillaceae rumA GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 ko00000,ko01000,ko03009 Bacteria 1TP4H@1239,3F41R@33958,4HA6M@91061,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family GOKNOHPG_00328 1033837.WANG_1130 4.7e-244 850.1 Lactobacillaceae nhaC ko:K03315 ko00000,ko02000 2.A.35 Bacteria 1TQ3B@1239,3F3VX@33958,4HA18@91061,COG1757@1,COG1757@2 NA|NA|NA C Na H antiporter NhaC GOKNOHPG_00329 1033837.WANG_1131 8e-52 209.5 Lactobacillaceae Bacteria 1UQJZ@1239,2BQGU@1,32JC9@2,3F6M4@33958,4IFJT@91061 NA|NA|NA GOKNOHPG_00330 1033837.WANG_1132 3.5e-118 431.0 Lactobacillaceae ybhL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06890 ko00000 Bacteria 1V779@1239,3F3QH@33958,4HIX1@91061,COG0670@1,COG0670@2 NA|NA|NA S Belongs to the BI1 family GOKNOHPG_00331 405566.lhv_2010 7.6e-70 269.6 Lactobacillaceae doc ko:K07341 ko00000,ko02048 Bacteria 1VCC8@1239,3F7JS@33958,4HKXW@91061,COG3654@1,COG3654@2 NA|NA|NA S Fic/DOC family GOKNOHPG_00332 1033837.WANG_p1186 2.6e-34 151.0 Lactobacillaceae Bacteria 1U6CP@1239,29PZ7@1,30A97@2,3F7M9@33958,4IG4E@91061 NA|NA|NA GOKNOHPG_00333 405566.lhv_2014 5.8e-149 533.5 Lactobacillaceae Bacteria 1TZWX@1239,3F4I5@33958,4HFD7@91061,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family GOKNOHPG_00334 405566.lhv_2015 2.5e-104 384.8 Lactobacillaceae Bacteria 1UY4S@1239,3FBF8@33958,4HD5D@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain GOKNOHPG_00335 405566.lhv_1953 5.4e-90 337.0 Bacilli Bacteria 1UZVH@1239,2BVJW@1,32QXP@2,4HFK6@91061 NA|NA|NA S Uncharacterised protein family (UPF0236) GOKNOHPG_00336 748671.LCRIS_01907 3.6e-155 554.3 Lactobacillaceae glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPX3@1239,3F3WI@33958,4H9ZF@91061,COG0554@1,COG0554@2 NA|NA|NA F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate GOKNOHPG_00337 1423767.BALU01000001_gene1512 2.5e-98 364.8 Lactobacillaceae glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPX3@1239,3F3WI@33958,4H9ZF@91061,COG0554@1,COG0554@2 NA|NA|NA F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate GOKNOHPG_00338 405566.lhv_2020 2.5e-152 544.7 Lactobacillaceae thiD GO:0008150,GO:0040007 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 ko:K00941,ko:K03147,ko:K21219 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R03472,R04509,R10712 RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ4A@1239,3F3NA@33958,4HAAH@91061,COG0351@1,COG0351@2 NA|NA|NA H Phosphomethylpyrimidine kinase GOKNOHPG_00340 326425.lhe_0242 1.9e-132 478.4 Lactobacillaceae cobQ ko:K07009 ko00000 Bacteria 1U7I9@1239,3F4CH@33958,4HD1P@91061,COG3442@1,COG3442@2 NA|NA|NA S glutamine amidotransferase GOKNOHPG_00341 405566.lhv_2023 9.5e-83 312.8 Lactobacillaceae Bacteria 1V9ZW@1239,3FC1P@33958,4HZ6Z@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family GOKNOHPG_00342 405566.lhv_2024 1.6e-158 565.5 Lactobacillaceae Bacteria 1TRTP@1239,3FBJS@33958,4HB3F@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family GOKNOHPG_00343 326425.lhe_0239 3.9e-108 397.5 Lactobacillaceae Bacteria 1UQ43@1239,2A5BR@1,30U1B@2,3F6BQ@33958,4IFET@91061 NA|NA|NA GOKNOHPG_00344 326425.lhe_0238 2.9e-41 174.9 Lactobacillaceae Bacteria 1U5BC@1239,29NPC@1,309M9@2,3F5FH@33958,4IF2P@91061 NA|NA|NA GOKNOHPG_00345 326425.lhe_0237 1.1e-31 142.1 Lactobacillaceae XK27_05540 Bacteria 1UR34@1239,3F4J5@33958,4HDF2@91061,COG1434@1,COG1434@2 NA|NA|NA S DUF218 domain GOKNOHPG_00346 326425.lhe_0237 4.5e-135 487.3 Lactobacillaceae XK27_05540 Bacteria 1UR34@1239,3F4J5@33958,4HDF2@91061,COG1434@1,COG1434@2 NA|NA|NA S DUF218 domain GOKNOHPG_00347 748671.LCRIS_01927 1.3e-180 639.4 Lactobacillaceae yheS_2 ko:K18231,ko:K19349,ko:K19350 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 3.A.1.121,3.A.1.121.1,3.A.1.121.2,3.A.1.121.3 Bacteria 1TQNA@1239,3F4UR@33958,4H9VW@91061,COG0488@1,COG0488@2 NA|NA|NA S ATPases associated with a variety of cellular activities GOKNOHPG_00348 326425.lhe_0235 1.3e-84 318.9 Lactobacillaceae Bacteria 1U5Q4@1239,2DKKP@1,309U8@2,3F6AJ@33958,4IFEC@91061 NA|NA|NA GOKNOHPG_00349 405566.lhv_2904 6.1e-58 229.9 Lactobacillaceae Bacteria 1U5UZ@1239,29NYM@1,309WQ@2,3F6IU@33958,4IFIM@91061 NA|NA|NA GOKNOHPG_00350 1033837.WANG_1421 8.4e-243 845.9 Lactobacillaceae purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1095 Bacteria 1TPMM@1239,3F48P@33958,4HACW@91061,COG0015@1,COG0015@2 NA|NA|NA F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily GOKNOHPG_00351 326425.lhe_0232 6.2e-246 856.3 Lactobacillaceae purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ4C@1239,3F3RQ@33958,4H9YT@91061,COG0104@1,COG0104@2 NA|NA|NA F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP GOKNOHPG_00352 405566.lhv_2031 3.7e-182 644.0 Lactobacillaceae guaC 1.1.1.205,1.7.1.7 ko:K00088,ko:K00364 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R01134,R08240 RC00143,RC00457,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iSB619.SA_RS06660 Bacteria 1TNYF@1239,3F45K@33958,4HA55@91061,COG0516@1,COG0516@2 NA|NA|NA F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides GOKNOHPG_00355 326425.lhe_0228 5.5e-200 703.4 Lactobacillaceae 4.2.1.126 ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 R08555 RC00397,RC00746 ko00000,ko00001,ko01000 Bacteria 1TRIY@1239,3FB4D@33958,4HAHJ@91061,COG3589@1,COG3589@2 NA|NA|NA S Bacterial protein of unknown function (DUF871) GOKNOHPG_00356 326425.lhe_0227 2.7e-188 664.5 Lactobacillaceae asnA GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 R00483 RC00010 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299 Bacteria 1TP28@1239,3F40A@33958,4HAEC@91061,COG2502@1,COG2502@2 NA|NA|NA F aspartate--ammonia ligase GOKNOHPG_00357 1423748.BALB01000014_gene1320 1.3e-230 805.4 Lactobacillaceae steT_1 Bacteria 1UZNT@1239,3F3SX@33958,4HFMI@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid GOKNOHPG_00358 1423748.BALB01000014_gene1321 2.7e-21 107.1 Lactobacillaceae puuD ko:K07010 ko00000,ko01002 Bacteria 1V1KC@1239,3F4PK@33958,4HI59@91061,COG2071@1,COG2071@2 NA|NA|NA S peptidase C26 GOKNOHPG_00359 326425.lhe_0221 7.3e-245 852.8 Lactobacillaceae yifK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03293 ko00000 2.A.3.1 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease GOKNOHPG_00360 326425.lhe_0220 4.9e-212 743.8 Lactobacillaceae cycA GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease GOKNOHPG_00361 326425.lhe_0219 5.3e-128 463.8 Lactobacillaceae Bacteria 1UGDF@1239,29V9A@1,30GPA@2,3F5SI@33958,4IF6B@91061 NA|NA|NA GOKNOHPG_00362 326425.lhe_0218 1.8e-116 425.2 Lactobacillaceae lepB 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1TRAV@1239,3FBKX@33958,4HCTU@91061,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family GOKNOHPG_00363 405566.lhv_2043 0.0 1337.4 Lactobacillaceae clpE ko:K03697 ko00000,ko03110 Bacteria 1TPMU@1239,3F5GX@33958,4HA0V@91061,COG0542@1,COG0542@2 NA|NA|NA O AAA domain (Cdc48 subfamily) GOKNOHPG_00364 326425.lhe_0216 3.7e-168 597.4 Lactobacillaceae Bacteria 1V8NG@1239,3F41V@33958,4HJ22@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF915) GOKNOHPG_00365 405566.lhv_2045 8.4e-208 729.6 Lactobacillaceae pts13C ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 Bacteria 1V5SI@1239,3F3Z5@33958,4HJTK@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane GOKNOHPG_00366 326425.lhe_0214 1.6e-83 315.5 Lactobacillaceae XK27_06785 ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQC9@1239,3F3YU@33958,4HB8D@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein GOKNOHPG_00367 326425.lhe_0214 2.2e-31 141.0 Lactobacillaceae XK27_06785 ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQC9@1239,3F3YU@33958,4HB8D@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein GOKNOHPG_00368 525365.HMPREF0548_1440 3.9e-113 414.5 Lactobacillaceae XK27_06780 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPHU@1239,3F4HF@33958,4HA2C@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease GOKNOHPG_00369 1423748.BALB01000014_gene1333 8e-71 273.1 Lactobacillaceae XK27_06780 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPHU@1239,3F4HF@33958,4HA2C@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease GOKNOHPG_00371 326425.lhe_0430 3.1e-189 667.5 Lactobacillaceae rfbD 1.1.1.133,5.1.3.13 ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777,R06514 RC00182,RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP71@1239,3F4QS@33958,4HBXF@91061,COG1091@1,COG1091@2 NA|NA|NA M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose GOKNOHPG_00372 748671.LCRIS_01734 1.4e-115 422.2 Lactobacillaceae rfbC 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 1TRVB@1239,3F4FN@33958,4HFQB@91061,COG1898@1,COG1898@2 NA|NA|NA M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose GOKNOHPG_00373 326425.lhe_0428 1.2e-163 582.4 Lactobacillaceae rfbA GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0334 Bacteria 1V301@1239,3F4F8@33958,4H9R0@91061,COG1209@1,COG1209@2 NA|NA|NA H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis GOKNOHPG_00374 326425.lhe_0427 1.2e-207 728.8 Lactobacillaceae rfbB 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPWM@1239,3F3R6@33958,4HA3Y@91061,COG1088@1,COG1088@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily GOKNOHPG_00375 326425.lhe_0426 5e-218 763.5 Lactobacillaceae Bacteria 1TSDZ@1239,3F5ZT@33958,4ISNQ@91061,COG0500@1,COG0789@1,COG0789@2,COG2226@2 NA|NA|NA KQ helix_turn_helix, mercury resistance GOKNOHPG_00377 1423754.BALY01000026_gene809 8.5e-212 743.0 Lactobacillaceae cps1C Bacteria 1TP7R@1239,3F48Q@33958,4HC84@91061,COG2244@1,COG2244@2 NA|NA|NA S Membrane protein involved in the export of O-antigen and teichoic acid GOKNOHPG_00378 405566.lhv_1794 2e-208 731.5 Lactobacillaceae glf GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 iNJ661.Rv3809c Bacteria 1TQB9@1239,3F52G@33958,4HB5F@91061,COG0562@1,COG0562@2 NA|NA|NA M UDP-galactopyranose mutase GOKNOHPG_00380 411474.COPEUT_02997 4e-51 208.4 Clostridia Bacteria 1U6EG@1239,24B83@186801,COG1442@1,COG1442@2 NA|NA|NA M Psort location Cytoplasmic, score GOKNOHPG_00381 515622.bpr_I2417 1.1e-40 174.1 Clostridia Bacteria 1VCNF@1239,252FN@186801,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase family 92 GOKNOHPG_00382 1226325.HMPREF1548_04160 4e-55 221.9 Clostridiaceae ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 GT2 Bacteria 1V5AQ@1239,24IBY@186801,36KV3@31979,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase, group 2 family protein GOKNOHPG_00383 1449338.JQLU01000005_gene2990 1.5e-50 206.8 Bacilli ko:K12997 ko00000,ko01000,ko01003,ko01005 GT2 Bacteria 1V2EP@1239,4HHPV@91061,COG0463@1,COG0463@2 NA|NA|NA M COG0463, glycosyltransferases involved in cell wall biogenesis GOKNOHPG_00384 1233951.IO90_01890 7.3e-46 191.4 Bacteria Bacteria COG4421@1,COG4421@2 NA|NA|NA G Protein of unknown function (DUF563) GOKNOHPG_00385 1226325.HMPREF1548_05774 8.8e-22 109.8 Clostridiaceae Bacteria 1UZRX@1239,24HX7@186801,36VJ3@31979,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase, group 2 family protein GOKNOHPG_00386 349123.Lreu23DRAFT_3750 6.3e-51 207.2 Bacteria Bacteria COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase, family 2 GOKNOHPG_00387 349123.Lreu23DRAFT_3749 2e-122 445.7 Lactobacillaceae ko:K19354 ko00000,ko01000,ko01003,ko01005 GT2 Bacteria 1VBC9@1239,3FBVD@33958,4HW8J@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 GOKNOHPG_00388 1423748.BALB01000028_gene1855 1.7e-34 152.1 Lactobacillaceae Bacteria 1UHSF@1239,3F428@33958,4HB04@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 GOKNOHPG_00389 257314.LJ_1029 6.2e-11 72.8 Lactobacillaceae Bacteria 1TRCM@1239,3F6H1@33958,4HC0S@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 GOKNOHPG_00390 658086.HMPREF0994_02131 9.3e-110 403.7 unclassified Lachnospiraceae Bacteria 1TPY6@1239,24834@186801,27Q3P@186928,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase 4-like domain GOKNOHPG_00391 405566.lhv_1803 2e-120 438.3 Lactobacillaceae rfbP Bacteria 1TP7M@1239,3FB5K@33958,4HHDH@91061,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase GOKNOHPG_00392 326425.lhe_0406 2.6e-143 514.6 Lactobacillaceae ywqE 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1TQ1T@1239,3F3RT@33958,4HDZR@91061,COG4464@1,COG4464@2 NA|NA|NA GM PHP domain protein GOKNOHPG_00393 405566.lhv_1805 2.4e-115 421.8 Lactobacillaceae ywqD 2.7.10.1 ko:K08252,ko:K16554 ko05111,map05111 ko00000,ko00001,ko01000,ko02000 8.A.3.1 Bacteria 1TS4R@1239,3F4BM@33958,4HCEN@91061,COG0489@1,COG0489@2 NA|NA|NA D Capsular exopolysaccharide family GOKNOHPG_00394 1033837.WANG_1298 2.3e-135 488.4 Lactobacillaceae epsB Bacteria 1UZCR@1239,3F4M5@33958,4HE26@91061,COG3944@1,COG3944@2 NA|NA|NA M biosynthesis protein GOKNOHPG_00395 405566.lhv_1807 1.2e-178 632.5 Lactobacillaceae brpA Bacteria 1TR1B@1239,3F3MQ@33958,4HA09@91061,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-like function transcriptional attenuator common domain protein GOKNOHPG_00396 405566.lhv_1808 3.6e-198 697.6 Lactobacillaceae hflX ko:K03665 ko00000,ko03009 Bacteria 1TNZB@1239,3F4B2@33958,4HACA@91061,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis GOKNOHPG_00397 326425.lhe_0400 3e-136 491.5 Lactobacillaceae ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1V5H7@1239,3FBE5@33958,4HMYU@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family GOKNOHPG_00398 326425.lhe_0399 7.3e-125 453.4 Lactobacillaceae ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1VG0Z@1239,3F50V@33958,4HBE9@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC P60 family protein GOKNOHPG_00399 405566.lhv_0211 2.4e-206 724.5 Lactobacillaceae Bacteria 1U7T5@1239,3F51F@33958,4HNFV@91061,COG0675@1,COG0675@2 NA|NA|NA L Putative transposase DNA-binding domain GOKNOHPG_00400 525365.HMPREF0548_1594 4.5e-41 173.7 Lactobacillaceae ko:K06921 ko00000 Bacteria 1TR21@1239,3F57U@33958,4HF7F@91061,COG1672@1,COG1672@2 NA|NA|NA S Archaea bacterial proteins of unknown function GOKNOHPG_00401 525365.HMPREF0548_1594 5.4e-33 146.7 Lactobacillaceae ko:K06921 ko00000 Bacteria 1TR21@1239,3F57U@33958,4HF7F@91061,COG1672@1,COG1672@2 NA|NA|NA S Archaea bacterial proteins of unknown function GOKNOHPG_00402 405566.lhv_1816 2.9e-91 341.3 Lactobacillaceae ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1V5H7@1239,3F4VI@33958,4IEXC@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family GOKNOHPG_00403 405566.lhv_1817 1e-93 349.4 Lactobacillaceae gmk2 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1VGNR@1239,3FBPU@33958,4IRT6@91061,COG0194@1,COG0194@2 NA|NA|NA F Guanylate kinase homologues. GOKNOHPG_00404 405566.lhv_1818 4.3e-25 120.6 Lactobacillaceae Bacteria 1U6CF@1239,2DKPT@1,30A91@2,3F7KP@33958,4IG44@91061 NA|NA|NA GOKNOHPG_00405 326425.lhe_0394 7.2e-278 962.6 Lactobacillaceae Bacteria 1V7RP@1239,2EZVI@1,33T01@2,3F4QD@33958,4IEWB@91061 NA|NA|NA S O-antigen ligase like membrane protein GOKNOHPG_00406 326425.lhe_0393 1.6e-93 349.0 Lactobacillaceae Bacteria 1U55V@1239,29DQI@1,300NC@2,3F4UQ@33958,4IEX6@91061 NA|NA|NA GOKNOHPG_00407 326425.lhe_1264 4.3e-198 697.2 Lactobacillaceae dnaJ ko:K03686 ko00000,ko03029,ko03110 Bacteria 1TP00@1239,3F490@33958,4H9KA@91061,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins GOKNOHPG_00408 405566.lhv_1336 0.0 1115.9 Lactobacillaceae dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 1TP1J@1239,3F48C@33958,4HA9S@91061,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein GOKNOHPG_00409 1423748.BALB01000013_gene1286 1.8e-80 305.4 Lactobacillaceae grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 ko:K03687 ko00000,ko03029,ko03110 Bacteria 1V6G2@1239,3F4DY@33958,4HIRK@91061,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ GOKNOHPG_00410 326425.lhe_1267 1.4e-184 652.1 Lactobacillaceae hrcA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K03705 ko00000,ko03000 Bacteria 1TQP7@1239,3F3ST@33958,4HAX5@91061,COG1420@1,COG1420@2 NA|NA|NA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons GOKNOHPG_00411 405566.lhv_1339 3e-181 641.0 Lactobacillaceae ribF 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS06310 Bacteria 1TPKS@1239,3F3TG@33958,4H9KE@91061,COG0196@1,COG0196@2 NA|NA|NA H Belongs to the ribF family GOKNOHPG_00412 405566.lhv_1340 1.7e-165 588.6 Lactobacillaceae truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 ko00000,ko01000,ko03000,ko03016 iSB619.SA_RS06305 Bacteria 1TP9Y@1239,3F3NX@33958,4HA9X@91061,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs GOKNOHPG_00413 405566.lhv_1341 3.3e-59 234.2 Lactobacillaceae rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 ko:K02834 ko00000,ko03009 Bacteria 1VA0P@1239,3F6WZ@33958,4HII1@91061,COG0858@1,COG0858@2 NA|NA|NA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA GOKNOHPG_00414 326425.lhe_1271 0.0 1396.3 Lactobacillaceae infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K02519 ko00000,ko03012,ko03029 Bacteria 1TPAI@1239,3F3JV@33958,4HA8S@91061,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex GOKNOHPG_00415 326425.lhe_1272 1.2e-46 192.2 Lactobacillaceae rplGA ko:K07590,ko:K07742 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEYG@1239,3F7ZK@33958,4HNY7@91061,COG1358@1,COG1358@2 NA|NA|NA J ribosomal protein GOKNOHPG_00416 405566.lhv_1344 3e-47 194.1 Lactobacillaceae ylxR ko:K02600,ko:K07742 ko00000,ko03009,ko03021 Bacteria 1VEJS@1239,3F7E2@33958,4HKBY@91061,COG2740@1,COG2740@2 NA|NA|NA K Protein of unknown function (DUF448) GOKNOHPG_00417 405566.lhv_1345 1.6e-192 678.7 Lactobacillaceae nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02600,ko:K02945 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03009,ko03011,ko03021 Bacteria 1TPB3@1239,3F3KZ@33958,4HA7F@91061,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination GOKNOHPG_00418 405566.lhv_1346 3.2e-83 314.3 Lactobacillaceae rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 ko:K09748 ko00000,ko03009 Bacteria 1V6KT@1239,3F6GZ@33958,4HH88@91061,COG0779@1,COG0779@2 NA|NA|NA J Required for maturation of 30S ribosomal subunits GOKNOHPG_00419 326425.lhe_1276 0.0 2783.1 Lactobacillaceae polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K02342,ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPAG@1239,3F4AN@33958,4H9RF@91061,COG2176@1,COG2176@2 NA|NA|NA L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity GOKNOHPG_00420 326425.lhe_1277 0.0 1114.4 Lactobacillaceae proS GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iJN678.proS,iUTI89_1310.UTI89_C0210 Bacteria 1TRBV@1239,3F44A@33958,4H9NN@91061,COG0442@1,COG0442@2 NA|NA|NA J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS GOKNOHPG_00421 326425.lhe_1278 8.8e-197 693.0 Lactobacillaceae rseP GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107,3.4.21.116 ko:K04771,ko:K06399,ko:K11749,ko:K16922 ko01503,ko02020,ko02024,ko04112,map01503,map02020,map02024,map04112 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1TPMC@1239,3F3TM@33958,4HAQ5@91061,COG0750@1,COG0750@2 NA|NA|NA M zinc metalloprotease GOKNOHPG_00422 326425.lhe_1279 1.6e-146 525.4 Lactobacillaceae cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1397 Bacteria 1UPNB@1239,3F4AF@33958,4IV81@91061,COG0575@1,COG0575@2 NA|NA|NA I Belongs to the CDS family GOKNOHPG_00423 326425.lhe_1280 5.4e-138 496.9 Lactobacillaceae uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 Bacteria 1TQTS@1239,3F42M@33958,4HA37@91061,COG0020@1,COG0020@2 NA|NA|NA H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids GOKNOHPG_00424 405566.lhv_1353 3.4e-92 344.4 Lactobacillaceae frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02838 ko00000,ko03012 Bacteria 1V1F2@1239,3F4X2@33958,4HFSH@91061,COG0233@1,COG0233@2 NA|NA|NA J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another GOKNOHPG_00425 1423748.BALB01000013_gene1269 4.5e-129 467.2 Lactobacillaceae pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 iSB619.SA_RS06240 Bacteria 1TPXN@1239,3F42J@33958,4H9UB@91061,COG0528@1,COG0528@2 NA|NA|NA F Catalyzes the reversible phosphorylation of UMP to UDP GOKNOHPG_00426 326425.lhe_1283 6.3e-185 653.3 Lactobacillaceae tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 ko:K02357 ko00000,ko03012,ko03029 Bacteria 1TPFJ@1239,3F459@33958,4HBDV@91061,COG0264@1,COG0264@2 NA|NA|NA J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome GOKNOHPG_00427 326425.lhe_1284 1.5e-138 498.8 Lactobacillaceae rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPNA@1239,3F3M1@33958,4H9N5@91061,COG0052@1,COG0052@2 NA|NA|NA J Belongs to the universal ribosomal protein uS2 family GOKNOHPG_00428 326425.lhe_1285 5.9e-199 699.9 Lactobacillaceae yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 ko00000,ko01000,ko03016 Bacteria 1TQ25@1239,3F4C5@33958,4HA8W@91061,COG2827@1,COG2827@2,COG4123@1,COG4123@2 NA|NA|NA L Methyltransferase small domain GOKNOHPG_00429 326425.lhe_1286 1.6e-111 408.7 Lactobacillaceae plsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1U8N2@1239,3F4QB@33958,4HDQR@91061,COG0204@1,COG0204@2 NA|NA|NA I Acyltransferase GOKNOHPG_00430 353496.LBU_1254 2.5e-225 787.7 Lactobacillaceae cfa 2.1.1.317,2.1.1.79 ko:K00574,ko:K20238 ko00000,ko01000 Bacteria 1TSG4@1239,3F3PA@33958,4HDKI@91061,COG2230@1,COG2230@2 NA|NA|NA M cyclopropane-fatty-acyl-phospholipid synthase GOKNOHPG_00431 405566.lhv_1360 0.0 1288.5 Lactobacillaceae pepO 3.4.24.71 ko:K01415,ko:K07386 ko00000,ko01000,ko01002,ko04147 Bacteria 1TQTA@1239,3F4CX@33958,4HDSF@91061,COG3590@1,COG3590@2 NA|NA|NA O Peptidase family M13 GOKNOHPG_00432 1423767.BALU01000005_gene968 1.8e-299 1034.6 Lactobacillaceae mdlB GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008144,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0033036,GO:0034040,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K06147,ko:K18890 ko02010,map02010 M00707 ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter GOKNOHPG_00433 748671.LCRIS_01291 1.6e-292 1011.5 Lactobacillaceae mdlA GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016021,GO:0017076,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K06148,ko:K18889 ko02010,map02010 M00707 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter GOKNOHPG_00434 326425.lhe_1641 2.2e-148 531.6 Lactobacillaceae yumC GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 1.18.1.2,1.19.1.1,1.8.1.9 ko:K00384,ko:K21567 ko00450,map00450 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 iYO844.BSU32110 Bacteria 1TRPN@1239,3F3NQ@33958,4H9V7@91061,COG0492@1,COG0492@2 NA|NA|NA C Ferredoxin--NADP reductase GOKNOHPG_00435 326425.lhe_1642 2e-115 421.8 Lactobacillaceae dedA ko:K03975 ko00000 Bacteria 1UZ4P@1239,3F4KG@33958,4HG3F@91061,COG0586@1,COG0586@2 NA|NA|NA S SNARE-like domain protein GOKNOHPG_00436 326425.lhe_1643 8.3e-84 316.6 Lactobacillaceae Bacteria 1V7UW@1239,3F4YP@33958,4HHH4@91061,COG4478@1,COG4478@2 NA|NA|NA S Protein of unknown function (DUF1461) GOKNOHPG_00437 326425.lhe_1644 7.5e-146 523.1 Lactobacillaceae nagD 2.7.1.25,3.1.3.41 ko:K00860,ko:K01101 ko00230,ko00627,ko00920,ko01100,ko01120,map00230,map00627,map00920,map01100,map01120 M00176 R00509,R03024,R04928 RC00002,RC00078,RC00151 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQGM@1239,3F49D@33958,4HA3R@91061,COG0647@1,COG0647@2 NA|NA|NA G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro GOKNOHPG_00438 405566.lhv_0461 1.7e-87 328.9 Lactobacillaceae yutD Bacteria 1VA85@1239,3F66P@33958,4HKF7@91061,COG4470@1,COG4470@2 NA|NA|NA S Protein of unknown function (DUF1027) GOKNOHPG_00439 405566.lhv_0460 7.3e-277 959.1 Lactobacillaceae yunD 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPV2@1239,3FC1D@33958,4H9VJ@91061,COG0737@1,COG0737@2 NA|NA|NA F Belongs to the 5'-nucleotidase family GOKNOHPG_00440 405566.lhv_0459 1.1e-55 222.2 Lactobacillaceae Bacteria 1VX4A@1239,2C26E@1,3424N@2,3F70Q@33958,4HXT9@91061 NA|NA|NA GOKNOHPG_00441 405566.lhv_0458 3.1e-264 917.1 Lactobacillaceae ugpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1V3W4@1239,3F4E3@33958,4HFNQ@91061,COG0584@1,COG0584@2 NA|NA|NA C glycerophosphoryl diester phosphodiesterase GOKNOHPG_00442 405566.lhv_0457 4.1e-181 640.6 Lactobacillaceae ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02529 ko00000,ko03000 Bacteria 1TQ7K@1239,3F4AA@33958,4H9NG@91061,COG1609@1,COG1609@2 NA|NA|NA K catabolite control protein A GOKNOHPG_00443 326425.lhe_1650 4.1e-214 750.4 Lactobacillaceae pepQ 3.4.13.9 ko:K01271 ko00000,ko01000,ko01002 Bacteria 1TQ6R@1239,3F3X5@33958,4HA5I@91061,COG0006@1,COG0006@2 NA|NA|NA E Creatinase/Prolidase N-terminal domain GOKNOHPG_00444 405566.lhv_0455 3e-44 184.5 Lactobacillaceae Bacteria 1U63A@1239,29P3Z@1,30A26@2,3F6XS@33958,4IFSN@91061 NA|NA|NA GOKNOHPG_00445 1423748.BALB01000002_gene199 3.3e-10 71.6 Lactobacillaceae WQ51_05790 Bacteria 1VAXN@1239,3F6KB@33958,4HM93@91061,COG4768@1,COG4768@2 NA|NA|NA S protein containing a divergent version of the methyl-accepting chemotaxis-like domain GOKNOHPG_00446 405566.lhv_0453 4.1e-153 547.4 Lactobacillaceae ykuT GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0042802,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 ko:K22044 ko00000,ko02000 1.A.23.3 Bacteria 1TR9Z@1239,3F49U@33958,4HCB8@91061,COG0668@1,COG0668@2 NA|NA|NA M mechanosensitive ion channel GOKNOHPG_00447 326425.lhe_1654 1.9e-115 421.8 Lactobacillaceae rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 1V6RN@1239,3F3KD@33958,4HCP6@91061,COG0127@1,COG0127@2 NA|NA|NA F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions GOKNOHPG_00448 326425.lhe_1655 3.5e-146 524.2 Lactobacillaceae murI GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 iYO844.BSU28390 Bacteria 1TPPR@1239,3F446@33958,4HA46@91061,COG0796@1,COG0796@2 NA|NA|NA M Provides the (R)-glutamate required for cell wall biosynthesis GOKNOHPG_00449 1423748.BALB01000002_gene203 8.5e-69 266.2 Lactobacillaceae yslB Bacteria 1VD7N@1239,3F7ZI@33958,4HKV3@91061,COG1719@1,COG1719@2 NA|NA|NA S Protein of unknown function (DUF2507) GOKNOHPG_00450 326425.lhe_1657 7.1e-38 163.3 Lactobacillaceae mscL GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 ko:K03282 ko00000,ko02000 1.A.22.1 Bacteria 1VA14@1239,3F6YZ@33958,4HKIA@91061,COG1970@1,COG1970@2 NA|NA|NA M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell GOKNOHPG_00451 1423748.BALB01000002_gene205 1e-53 215.7 Lactobacillaceae trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1VA3Y@1239,3F6Y3@33958,4HKKX@91061,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family GOKNOHPG_00452 405566.lhv_0442 0.0 1313.1 Lactobacillaceae mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TP5W@1239,3F4DX@33958,4H9NZ@91061,COG1193@1,COG1193@2 NA|NA|NA L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity GOKNOHPG_00453 326425.lhe_1660 6.2e-51 206.5 Lactobacillaceae yrzB Bacteria 1VAPW@1239,3F6X3@33958,4HKV7@91061,COG3906@1,COG3906@2 NA|NA|NA S Belongs to the UPF0473 family GOKNOHPG_00454 1423748.BALB01000002_gene208 1e-72 279.3 Lactobacillaceae yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07447 ko00000,ko01000 Bacteria 1V6ER@1239,3F6NI@33958,4HH04@91061,COG0816@1,COG0816@2 NA|NA|NA J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA GOKNOHPG_00455 1033837.WANG_0122 2e-42 177.9 Lactobacillaceae yrzL Bacteria 1VAC4@1239,3F7EG@33958,4HKD0@91061,COG4472@1,COG4472@2 NA|NA|NA S Belongs to the UPF0297 family GOKNOHPG_00456 405566.lhv_0438 0.0 1747.6 Lactobacillaceae alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPK6@1239,3F3QS@33958,4H9XC@91061,COG0013@1,COG0013@2 NA|NA|NA J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain GOKNOHPG_00457 405566.lhv_0437 1.2e-85 322.4 Lactobacillaceae Bacteria 1VG2M@1239,2ERDT@1,33IZD@2,3F8CY@33958,4IGIT@91061 NA|NA|NA GOKNOHPG_00458 97137.C821_01309 1.9e-64 251.9 Lactobacillaceae Bacteria 1U7TP@1239,29QBD@1,30BAK@2,3FA5W@33958,4IHR5@91061 NA|NA|NA GOKNOHPG_00459 1033837.WANG_0120 5.2e-235 820.1 Lactobacillaceae cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TPAP@1239,3F4FQ@33958,4HA98@91061,COG0513@1,COG0513@2 NA|NA|NA JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures GOKNOHPG_00460 326425.lhe_1665 8.8e-181 639.4 Lactobacillaceae nrnA GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPXX@1239,3F4FC@33958,4H9ZW@91061,COG0618@1,COG0618@2 NA|NA|NA S DHHA1 domain protein GOKNOHPG_00461 326425.lhe_1666 7.1e-214 749.6 Lactobacillaceae dinB GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031668,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 ko:K02346 ko00000,ko01000,ko03400 Bacteria 1TP42@1239,3F44N@33958,4HADJ@91061,COG0389@1,COG0389@2 NA|NA|NA L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII GOKNOHPG_00462 405566.lhv_0432 2e-280 971.1 Lactobacillaceae zwf GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 iIT341.HP1101 Bacteria 1TPYF@1239,3F48G@33958,4HA73@91061,COG0364@1,COG0364@2 NA|NA|NA G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone GOKNOHPG_00463 405566.lhv_0431 2.4e-37 161.8 Lactobacillaceae yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VEMC@1239,3F7EY@33958,4HNK0@91061,COG1862@1,COG1862@2 NA|NA|NA U Preprotein translocase GOKNOHPG_00464 405566.lhv_0430 3e-187 661.0 Lactobacillaceae ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TR47@1239,3F47S@33958,4HBMW@91061,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing GOKNOHPG_00465 1423748.BALB01000002_gene217 5.9e-103 380.2 Lactobacillaceae ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1V3KF@1239,3F42W@33958,4HHI5@91061,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB GOKNOHPG_00466 326425.lhe_1671 0.0 1214.1 Lactobacillaceae mutL GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TPGK@1239,3F3PK@33958,4HB34@91061,COG0323@1,COG0323@2 NA|NA|NA L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex GOKNOHPG_00467 326425.lhe_1672 0.0 1666.4 Lactobacillaceae mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TPRJ@1239,3F4A5@33958,4HA63@91061,COG0249@1,COG0249@2 NA|NA|NA L that it carries out the mismatch recognition step. This protein has a weak ATPase activity GOKNOHPG_00468 405566.lhv_0426 1.5e-289 1001.5 Lactobacillaceae groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 1TP1T@1239,3F3MM@33958,4HA38@91061,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions GOKNOHPG_00469 1423748.BALB01000002_gene222 3e-44 184.1 Lactobacillaceae groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0032991,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:0101031,GO:1903506,GO:1990220,GO:2000112,GO:2001141 ko:K04078 ko00000,ko03029,ko03110 Bacteria 1V9ZM@1239,3F7CZ@33958,4HKEK@91061,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter GOKNOHPG_00470 405566.lhv_0423 1.8e-90 338.6 Lactobacillaceae Bacteria 1U5M7@1239,2CHFM@1,301I5@2,3F66G@33958,4IFC0@91061 NA|NA|NA GOKNOHPG_00471 326425.lhe_1681 6.1e-46 189.9 Lactobacillaceae Bacteria 1UPY3@1239,2DN64@1,32VRU@2,3FC0U@33958,4IVD5@91061 NA|NA|NA GOKNOHPG_00472 891391.LAC30SC_01990 6.2e-129 466.8 Lactobacillaceae scrA 2.7.1.208,2.7.1.211,5.3.1.1 ko:K01803,ko:K02749,ko:K02750,ko:K02808,ko:K02809,ko:K02810 ko00010,ko00051,ko00500,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko02060,map00010,map00051,map00500,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map02060 M00001,M00002,M00003,M00268,M00269 R00811,R01015,R04111 RC00017,RC00423,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko04147 4.A.1.1.10,4.A.1.1.16,4.A.1.1.4,4.A.1.1.8,4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system GOKNOHPG_00473 1423748.BALB01000002_gene226 5.8e-124 450.3 Lactobacillaceae scrA 2.7.1.211,5.3.1.1 ko:K01803,ko:K02808,ko:K02809,ko:K02810 ko00010,ko00051,ko00500,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko02060,map00010,map00051,map00500,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map02060 M00001,M00002,M00003,M00269 R00811,R01015 RC00017,RC00423,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko04147 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system GOKNOHPG_00474 1033837.WANG_p1012 7.4e-236 822.8 Lactobacillaceae Bacteria 1TQ93@1239,3F4RD@33958,4HDNZ@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein GOKNOHPG_00475 326425.lhe_1684 2.5e-122 444.9 Lactobacillaceae liaI ko:K11619 ko02020,map02020 M00754 ko00000,ko00001,ko00002 Bacteria 1V7WJ@1239,3F6JJ@33958,4HR21@91061,COG4758@1,COG4758@2 NA|NA|NA S membrane GOKNOHPG_00476 405566.lhv_0417 4.3e-77 293.9 Lactobacillaceae XK27_02470 Bacteria 1VBF7@1239,3F7K4@33958,4IPQI@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain GOKNOHPG_00477 326425.lhe_1686 1.8e-113 415.2 Lactobacillaceae rex ko:K01926 ko00000,ko03000 Bacteria 1TSMR@1239,3F40G@33958,4HB7Q@91061,COG2344@1,COG2344@2 NA|NA|NA K Modulates transcription in response to changes in cellular NADH NAD( ) redox state GOKNOHPG_00478 326425.lhe_1687 0.0 1101.7 Lactobacillaceae uup ko:K06158 ko00000,ko03012 Bacteria 1TPAX@1239,3F3QI@33958,4HBVV@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein GOKNOHPG_00479 405566.lhv_0796 1.9e-279 968.0 Lactobacillaceae Bacteria 1TQQ9@1239,3F4M8@33958,4H9KK@91061,COG3666@1,COG3666@2 NA|NA|NA L Transposase GOKNOHPG_00480 1423748.BALB01000002_gene239 1.5e-194 685.3 Lactobacillaceae tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1TQDR@1239,3F4AX@33958,4HANB@91061,COG0533@1,COG0533@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction GOKNOHPG_00481 326425.lhe_1695 2.6e-103 381.3 Lactobacillaceae rimI 2.3.1.128 ko:K03789 ko00000,ko01000,ko03009 Bacteria 1V6KU@1239,3F522@33958,4HIKU@91061,COG0454@1,COG0456@2 NA|NA|NA K Ribosomal-protein-alanine acetyltransferase GOKNOHPG_00482 405566.lhv_0411 1.3e-131 475.7 Lactobacillaceae yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03016 Bacteria 1V4YX@1239,3F3WV@33958,4HHD7@91061,COG1214@1,COG1214@2 NA|NA|NA O Universal bacterial protein YeaZ GOKNOHPG_00483 1033837.WANG_0084 2.4e-81 308.1 Lactobacillaceae Bacteria 1VGAX@1239,2DNHW@1,32XKY@2,3FBRP@33958,4ISA7@91061 NA|NA|NA S ECF transporter, substrate-specific component GOKNOHPG_00484 1033837.WANG_0083 7.3e-143 513.1 Lactobacillaceae fat 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 Bacteria 1V3RB@1239,3F41B@33958,4HHJ4@91061,COG3884@1,COG3884@2 NA|NA|NA I Acyl-ACP thioesterase GOKNOHPG_00485 326425.lhe_1699 1.5e-155 555.4 Lactobacillaceae rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 1TP6U@1239,3F4AI@33958,4HAH8@91061,COG0313@1,COG0313@2 NA|NA|NA H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA GOKNOHPG_00486 1423748.BALB01000002_gene245 1.6e-58 231.9 Lactobacillaceae yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 Bacteria 1VA1F@1239,3F864@33958,4HKND@91061,COG4467@1,COG4467@2 NA|NA|NA L Involved in initiation control of chromosome replication GOKNOHPG_00487 326425.lhe_1701 6.3e-154 550.1 Lactobacillaceae holB 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TRVS@1239,3F50D@33958,4HA3T@91061,COG0470@1,COG0470@2 NA|NA|NA L DNA polymerase III GOKNOHPG_00488 405566.lhv_0405 1.1e-50 205.7 Lactobacillaceae yaaQ Bacteria 1V6NI@1239,3F6VW@33958,4HIHA@91061,COG3870@1,COG3870@2 NA|NA|NA S Cyclic-di-AMP receptor GOKNOHPG_00489 326425.lhe_1703 8.7e-116 422.9 Lactobacillaceae tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS02535 Bacteria 1V1HE@1239,3F4JR@33958,4HGWR@91061,COG0125@1,COG0125@2 NA|NA|NA F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis GOKNOHPG_00490 326425.lhe_1704 2.6e-33 147.5 Lactobacillaceae Bacteria 1U6E6@1239,29PC5@1,30AAD@2,3F7PR@33958,4IG5Y@91061 NA|NA|NA S Protein of unknown function (DUF2508) GOKNOHPG_00491 326425.lhe_1705 2.1e-108 398.3 Lactobacillaceae recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1TR87@1239,3F4JQ@33958,4HAZR@91061,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO GOKNOHPG_00492 1423748.BALB01000002_gene252 2.5e-37 161.4 Lactobacillaceae yaaK ko:K09747 ko00000 Bacteria 1VA1S@1239,3F7F3@33958,4HKH3@91061,COG0718@1,COG0718@2 NA|NA|NA S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection GOKNOHPG_00493 405566.lhv_0400 0.0 1118.6 Lactobacillaceae dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02341,ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPS9@1239,3F3P2@33958,4HAUE@91061,COG2812@1,COG2812@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity GOKNOHPG_00494 326425.lhe_1708 2e-91 341.7 Lactobacillaceae tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 R10223 RC00477 ko00000,ko01000,ko03016 Bacteria 1V3HZ@1239,3F6IS@33958,4HH7S@91061,COG0590@1,COG0590@2 NA|NA|NA F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) GOKNOHPG_00495 326425.lhe_1709 7.2e-115 419.9 Lactobacillaceae rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1V1BG@1239,3F4NU@33958,4HHCA@91061,COG2813@1,COG2813@2 NA|NA|NA J Methyltransferase GOKNOHPG_00496 1423748.BALB01000002_gene255 4.6e-26 123.6 Lactobacillaceae rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172,2.1.1.80,3.1.1.61 ko:K00564,ko:K02026,ko:K10716,ko:K11070,ko:K13924,ko:K14393 ko02010,ko02020,ko02030,map02010,map02020,map02030 M00207,M00299,M00506 R07234 RC00003 ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035,ko03009 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6,2.A.21.7,3.A.1.1,3.A.1.11.1 Bacteria 1UI94@1239,3FBT5@33958,4HFS7@91061,COG1340@1,COG1340@2,COG2813@1,COG2813@2 NA|NA|NA J Ion channel GOKNOHPG_00497 1423748.BALB01000002_gene255 1.3e-36 158.7 Lactobacillaceae rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172,2.1.1.80,3.1.1.61 ko:K00564,ko:K02026,ko:K10716,ko:K11070,ko:K13924,ko:K14393 ko02010,ko02020,ko02030,map02010,map02020,map02030 M00207,M00299,M00506 R07234 RC00003 ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035,ko03009 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6,2.A.21.7,3.A.1.1,3.A.1.11.1 Bacteria 1UI94@1239,3FBT5@33958,4HFS7@91061,COG1340@1,COG1340@2,COG2813@1,COG2813@2 NA|NA|NA J Ion channel GOKNOHPG_00498 1423748.BALB01000002_gene256 7e-54 216.5 Lactobacillaceae rplL ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6EI@1239,3F6YA@33958,4HIGQ@91061,COG0222@1,COG0222@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation GOKNOHPG_00499 1423748.BALB01000002_gene257 6.6e-82 310.1 Lactobacillaceae rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3JJ@1239,3F4S4@33958,4HH0N@91061,COG0244@1,COG0244@2 NA|NA|NA J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors GOKNOHPG_00500 1423748.BALB01000002_gene258 4.2e-90 337.4 Lactobacillaceae yfdV GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07088 ko00000 iECW_1372.ECW_m2605,iWFL_1372.ECW_m2605 Bacteria 1VDS9@1239,3F5JF@33958,4HQT5@91061,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein GOKNOHPG_00501 1423748.BALB01000002_gene258 1.3e-35 155.2 Lactobacillaceae yfdV GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07088 ko00000 iECW_1372.ECW_m2605,iWFL_1372.ECW_m2605 Bacteria 1VDS9@1239,3F5JF@33958,4HQT5@91061,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein GOKNOHPG_00502 272621.LBA0367 2.8e-26 124.0 Lactobacillaceae yfdV GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07088 ko00000 iECW_1372.ECW_m2605,iWFL_1372.ECW_m2605 Bacteria 1VDS9@1239,3F5JF@33958,4HQT5@91061,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein GOKNOHPG_00503 326425.lhe_1714 5.4e-116 423.7 Lactobacillaceae phoU ko:K02039 ko00000 Bacteria 1URN3@1239,3F46W@33958,4HEU9@91061,COG0704@1,COG0704@2 NA|NA|NA P Plays a role in the regulation of phosphate uptake GOKNOHPG_00504 326425.lhe_1715 1.9e-138 498.4 Lactobacillaceae pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 iLJ478.TM1261 Bacteria 1TP1M@1239,3F3SY@33958,4HAB1@91061,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system GOKNOHPG_00505 326425.lhe_1716 9.3e-144 516.2 Lactobacillaceae pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 iLJ478.TM1261 Bacteria 1TP1M@1239,3F3SY@33958,4HAB1@91061,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system GOKNOHPG_00506 326425.lhe_1717 1.5e-153 548.9 Lactobacillaceae pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TP74@1239,3F412@33958,4HAKF@91061,COG0581@1,COG0581@2 NA|NA|NA P Phosphate transport system permease protein PstA GOKNOHPG_00507 326425.lhe_1718 1.1e-173 615.9 Lactobacillaceae pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02037 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TSPP@1239,3F3NI@33958,4HC9H@91061,COG0573@1,COG0573@2 NA|NA|NA P probably responsible for the translocation of the substrate across the membrane GOKNOHPG_00508 405566.lhv_0387 9.5e-158 562.8 Lactobacillaceae pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TQ5X@1239,3F4ER@33958,4HBEB@91061,COG0226@1,COG0226@2 NA|NA|NA P Phosphate GOKNOHPG_00509 326425.lhe_1720 9.4e-124 449.5 Lactobacillaceae rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPTS@1239,3F3VQ@33958,4HAK4@91061,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release GOKNOHPG_00510 1423748.BALB01000002_gene267 3.8e-67 260.8 Lactobacillaceae rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1BS@1239,3F64I@33958,4HFQ0@91061,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors GOKNOHPG_00511 326425.lhe_1722 3.1e-101 374.4 Lactobacillaceae nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 1TR3P@1239,3F55W@33958,4HAJA@91061,COG0250@1,COG0250@2 NA|NA|NA K Participates in transcription elongation, termination and antitermination GOKNOHPG_00512 326425.lhe_1723 5.9e-24 115.9 Lactobacillaceae secE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VK48@1239,3F86Y@33958,4HR1W@91061,COG0690@1,COG0690@2 NA|NA|NA U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation GOKNOHPG_00513 1423748.BALB01000002_gene270 0.0 1114.4 Lactobacillaceae dxs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP37@1239,3F4RN@33958,4H9QW@91061,COG1154@1,COG1154@2 NA|NA|NA H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) GOKNOHPG_00514 405566.lhv_0375 4.5e-280 969.9 Lactobacillaceae gntK 2.7.1.12,2.7.1.17 ko:K00851,ko:K00854 ko00030,ko00040,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map01100,map01110,map01120,map01130,map01200 M00014 R01639,R01737 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ1I@1239,3F4R2@33958,4H9W6@91061,COG1070@1,COG1070@2 NA|NA|NA G Belongs to the FGGY kinase family GOKNOHPG_00515 272621.LBA0352 2.2e-34 151.0 Lactobacillaceae Bacteria 1U6KC@1239,29PH8@1,30AFD@2,3F83D@33958,4IGD6@91061 NA|NA|NA GOKNOHPG_00516 326425.lhe_1727 2.6e-92 344.7 Lactobacillaceae sigH ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Bacteria 1VG7U@1239,3F8D5@33958,4HNKD@91061,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family GOKNOHPG_00517 405566.lhv_0372 3.3e-138 497.7 Lactobacillaceae rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218,ko:K03437,ko:K12952 ko00000,ko01000,ko03009,ko03016 3.A.3.23 Bacteria 1TP9G@1239,3F3TD@33958,4HBBI@91061,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family GOKNOHPG_00518 326425.lhe_1729 1.4e-75 288.9 Lactobacillaceae mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 ko:K11145 ko00000,ko01000,ko03009 Bacteria 1VA5V@1239,3F6HS@33958,4HIM3@91061,COG1939@1,COG1939@2 NA|NA|NA J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) GOKNOHPG_00519 405566.lhv_0370 7.3e-272 942.6 Lactobacillaceae cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16,6.3.1.13 ko:K01883,ko:K15526 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECUMN_1333.ECUMN_0566,iJN746.PP_2905 Bacteria 1TP9D@1239,3F4K7@33958,4HA6D@91061,COG0215@1,COG0215@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family GOKNOHPG_00520 405566.lhv_0369 9.6e-291 1005.4 Lactobacillaceae gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009986,GO:0030246,GO:0030247,GO:0044424,GO:0044464,GO:2001065 6.1.1.17,6.1.1.24 ko:K01885,ko:K09698 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 iSB619.SA_RS02860 Bacteria 1TPJC@1239,3F3PR@33958,4HAKH@91061,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) GOKNOHPG_00521 1423748.BALB01000002_gene280 2.1e-252 877.9 Lactobacillaceae radA ko:K04485 ko00000,ko03400 Bacteria 1TQ7Y@1239,3F3W8@33958,4H9YC@91061,COG1066@1,COG1066@2 NA|NA|NA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function GOKNOHPG_00522 405566.lhv_0367 4.7e-102 377.1 Lactobacillaceae dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 ko:K01520,ko:K13038 ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100 M00053,M00120 R02100,R03269,R04231,R11896 RC00002,RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1V6HX@1239,3F65D@33958,4HIZ3@91061,COG0756@1,COG0756@2 NA|NA|NA F dUTP diphosphatase GOKNOHPG_00523 326425.lhe_1734 4.5e-54 216.9 Lactobacillaceae Bacteria 1U6EY@1239,2BRXH@1,32KXS@2,3F7RT@33958,4IG6S@91061 NA|NA|NA GOKNOHPG_00524 1423748.BALB01000002_gene283 4e-264 916.8 Lactobacillaceae pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 1TRJN@1239,3F49B@33958,4HBZ9@91061,COG3579@1,COG3579@2 NA|NA|NA E Peptidase C1-like family GOKNOHPG_00525 1033837.WANG_0042 1.1e-142 512.7 Lactobacillaceae glcU ko:K05340 ko00000,ko02000 2.A.7.5 Bacteria 1TQBN@1239,3F4K2@33958,4HAVH@91061,COG4975@1,COG4975@2 NA|NA|NA U sugar transport GOKNOHPG_00526 405566.lhv_0178 2.4e-239 834.3 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TT4J@1239,3FB6R@33958,4IRBE@91061,COG0675@1,COG0675@2 NA|NA|NA L Probable transposase GOKNOHPG_00527 405566.lhv_0361 4.3e-23 113.6 Lactobacillaceae Bacteria 1VKTU@1239,2DS5S@1,33ENY@2,3F6MW@33958,4HSXX@91061 NA|NA|NA GOKNOHPG_00528 405566.lhv_0360 0.0 1581.6 Lactobacillaceae mgtA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132 3.6.3.2 ko:K01531 ko00000,ko01000 3.A.3.4 iSF_1195.SF4248 Bacteria 1TPF5@1239,3F4E0@33958,4HBQJ@91061,COG0474@1,COG0474@2 NA|NA|NA P COG0474 Cation transport ATPase GOKNOHPG_00529 525365.HMPREF0548_2086 2.5e-180 637.9 Lactobacillaceae Bacteria 1TQKR@1239,3F51A@33958,4HF9B@91061,COG4639@1,COG4639@2 NA|NA|NA S AAA domain GOKNOHPG_00530 405566.lhv_0354 7.5e-126 456.4 Lactobacillaceae gpmA GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1V2UT@1239,3F443@33958,4HGRK@91061,COG0588@1,COG0588@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate GOKNOHPG_00531 326425.lhe_1741 5.5e-23 112.8 Lactobacillaceae Bacteria 1U6P8@1239,29PJE@1,30AHJ@2,3F88U@33958,4IGG9@91061 NA|NA|NA GOKNOHPG_00532 405566.lhv_0353 3e-162 577.8 Lactobacillaceae czcD ko:K16264 ko00000,ko02000 2.A.4.1 Bacteria 1TR92@1239,3F4KJ@33958,4HBCQ@91061,COG1230@1,COG1230@2 NA|NA|NA P cation diffusion facilitator family transporter GOKNOHPG_00533 326425.lhe_1743 8.3e-125 453.0 Lactobacillaceae pgm3 Bacteria 1TQF1@1239,3F4RY@33958,4I2XH@91061,COG0406@1,COG0406@2 NA|NA|NA G Belongs to the phosphoglycerate mutase family GOKNOHPG_00534 405566.lhv_0350 1.6e-70 271.9 Lactobacillaceae ko:K07090 ko00000 Bacteria 1VR9G@1239,3F3TR@33958,4HV4W@91061,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein GOKNOHPG_00535 405566.lhv_0350 2e-22 111.7 Lactobacillaceae ko:K07090 ko00000 Bacteria 1VR9G@1239,3F3TR@33958,4HV4W@91061,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein GOKNOHPG_00536 1423748.BALB01000002_gene293 4.8e-109 400.6 Lactobacillaceae 3.1.3.18,3.8.1.2 ko:K01091,ko:K01560,ko:K07025,ko:K11777 ko00361,ko00625,ko00630,ko01100,ko01110,ko01120,ko01130,map00361,map00625,map00630,map01100,map01110,map01120,map01130 R01334,R05287 RC00017,RC00697 ko00000,ko00001,ko01000 Bacteria 1UMZH@1239,3FBY3@33958,4IU43@91061,COG0546@1,COG0546@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase GOKNOHPG_00537 326425.lhe_1746 2.7e-108 397.9 Lactobacillaceae thiJ 2.7.11.1,3.5.1.124 ko:K03152,ko:K05520,ko:K12132 ko00000,ko01000,ko01001,ko01002 Bacteria 1V3UV@1239,3F3T7@33958,4IQYM@91061,COG0693@1,COG0693@2 NA|NA|NA S DJ-1/PfpI family GOKNOHPG_00538 405566.lhv_0347 2.7e-61 241.5 Lactobacillaceae Bacteria 1VDSW@1239,3F4C0@33958,4HMMJ@91061,COG3152@1,COG3152@2 NA|NA|NA S Protein of unknown function (DUF805) GOKNOHPG_00539 1423748.BALB01000002_gene295 4.6e-67 260.4 Lactobacillaceae rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3MQ@1239,3F656@33958,4HH3B@91061,COG0103@1,COG0103@2 NA|NA|NA J Belongs to the universal ribosomal protein uS9 family GOKNOHPG_00540 1423748.BALB01000002_gene296 5e-78 297.0 Lactobacillaceae rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3HX@1239,3F696@33958,4HG0I@91061,COG0102@1,COG0102@2 NA|NA|NA J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly GOKNOHPG_00541 405566.lhv_0342 2.3e-142 511.5 Lactobacillaceae truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 1TQUY@1239,3F4KC@33958,4HCFI@91061,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs GOKNOHPG_00542 405566.lhv_0341 2e-138 498.4 Lactobacillaceae ecfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 ko:K02008,ko:K16783,ko:K16785 ko02010,map02010 M00245,M00246,M00581,M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TQ0E@1239,3F3UW@33958,4H9VT@91061,COG0619@1,COG0619@2 NA|NA|NA U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates GOKNOHPG_00543 326425.lhe_1761 4e-150 537.3 Lactobacillaceae ecfA GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008144,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032217,GO:0032218,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035461,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0097159,GO:0097367,GO:0098656,GO:1901265,GO:1901363 3.6.3.55 ko:K01990,ko:K02068,ko:K06857,ko:K16784,ko:K16786,ko:K16787 ko02010,map02010 M00186,M00211,M00254,M00581,M00582 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35,3.A.1.6.2,3.A.1.6.4 Bacteria 1TPH8@1239,3F48E@33958,4HA7T@91061,COG1122@1,COG1122@2 NA|NA|NA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates GOKNOHPG_00544 326425.lhe_1762 8.5e-151 539.7 Lactobacillaceae ecfA1 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 ko:K01990,ko:K16784,ko:K16786,ko:K16787 ko02010,map02010 M00254,M00581,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPH8@1239,3F3VD@33958,4H9R8@91061,COG1122@1,COG1122@2 NA|NA|NA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates GOKNOHPG_00545 1423748.BALB01000002_gene302 1.1e-60 239.2 Lactobacillaceae rplQ GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02879,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6JQ@1239,3F6GJ@33958,4HGX2@91061,COG0203@1,COG0203@2 NA|NA|NA J Ribosomal protein L17 GOKNOHPG_00546 405566.lhv_0337 1.5e-169 602.1 Lactobacillaceae rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TPR8@1239,3F3W6@33958,4H9R1@91061,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates GOKNOHPG_00547 1033837.WANG_0019 5.2e-63 246.9 Lactobacillaceae rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02948 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3IK@1239,3F67D@33958,4HH2T@91061,COG0100@1,COG0100@2 NA|NA|NA J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome GOKNOHPG_00548 405566.lhv_0335 2.1e-55 221.5 Lactobacillaceae rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02952 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3JH@1239,3F6GN@33958,4HGX6@91061,COG0099@1,COG0099@2 NA|NA|NA J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits GOKNOHPG_00549 1423748.BALB01000002_gene306 7.8e-15 85.1 Lactobacillaceae rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02919 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VK4F@1239,3F8TC@33958,4HR2X@91061,COG0257@1,COG0257@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL36 family GOKNOHPG_00550 1423748.BALB01000002_gene307 8.4e-34 149.1 Lactobacillaceae infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009986,GO:0016020,GO:0030246,GO:0030247,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 1V9ZK@1239,3F7CW@33958,4HKF4@91061,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex GOKNOHPG_00551 405566.lhv_0333 2.7e-120 438.0 Lactobacillaceae adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS20110 Bacteria 1TP27@1239,3F3KB@33958,4HA89@91061,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism GOKNOHPG_00552 326425.lhe_1769 2.2e-235 821.2 Lactobacillaceae secY GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0040007,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5 Bacteria 1TPHB@1239,3F4FV@33958,4HAWH@91061,COG0201@1,COG0201@2 NA|NA|NA U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently GOKNOHPG_00553 1423748.BALB01000002_gene310 5.9e-71 273.5 Lactobacillaceae rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02876 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3KE@1239,3F675@33958,4HFPW@91061,COG0200@1,COG0200@2 NA|NA|NA J Binds to the 23S rRNA GOKNOHPG_00554 326425.lhe_1771 2.3e-24 117.5 Lactobacillaceae rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02907 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEG4@1239,3F7ZU@33958,4HNHF@91061,COG1841@1,COG1841@2 NA|NA|NA J Ribosomal protein L30 GOKNOHPG_00555 1423748.BALB01000002_gene312 1.8e-84 318.5 Lactobacillaceae rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02988 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1B1@1239,3F3VY@33958,4HFN4@91061,COG0098@1,COG0098@2 NA|NA|NA J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body GOKNOHPG_00556 1423748.BALB01000002_gene313 1.1e-54 219.2 Lactobacillaceae rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02881 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6DM@1239,3F6KN@33958,4HIGF@91061,COG0256@1,COG0256@2 NA|NA|NA J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance GOKNOHPG_00557 405566.lhv_0327 4.7e-91 340.5 Lactobacillaceae rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02933 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1FC@1239,3F4G5@33958,4HFQD@91061,COG0097@1,COG0097@2 NA|NA|NA J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center GOKNOHPG_00558 1423748.BALB01000002_gene315 3.6e-67 260.8 Lactobacillaceae rpsH GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904 ko:K02994 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3KK@1239,3F64E@33958,4HH32@91061,COG0096@1,COG0096@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit GOKNOHPG_00559 1423748.BALB01000002_gene316 8.9e-29 132.1 Lactobacillaceae rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEF6@1239,3FB5M@33958,4HNKX@91061,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site GOKNOHPG_00560 405566.lhv_0324 3.6e-94 350.9 Lactobacillaceae rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02931 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPE0@1239,3F3Q7@33958,4HBAX@91061,COG0094@1,COG0094@2 NA|NA|NA J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits GOKNOHPG_00561 405566.lhv_0323 9.8e-33 145.6 Lactobacillaceae rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02895 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9ZQ@1239,3F6X5@33958,4HKH9@91061,COG0198@1,COG0198@2 NA|NA|NA J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit GOKNOHPG_00562 1423748.BALB01000002_gene319 1.5e-59 235.3 Lactobacillaceae rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02874 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3N0@1239,3F6GT@33958,4HGYR@91061,COG0093@1,COG0093@2 NA|NA|NA J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome GOKNOHPG_00563 1423748.BALB01000002_gene320 1.9e-40 171.4 Lactobacillaceae rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02961 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9YC@1239,3F7FX@33958,4HKDN@91061,COG0186@1,COG0186@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA GOKNOHPG_00564 405566.lhv_0320 3.7e-25 120.2 Lactobacillaceae rpmC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02904 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEME@1239,3F82Z@33958,4HNUP@91061,COG0255@1,COG0255@2 NA|NA|NA J Belongs to the universal ribosomal protein uL29 family GOKNOHPG_00565 1423748.BALB01000002_gene322 6e-76 290.0 Lactobacillaceae rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02878 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1AY@1239,3F653@33958,4HFPN@91061,COG0197@1,COG0197@2 NA|NA|NA J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs GOKNOHPG_00566 326425.lhe_1783 1.7e-109 402.1 Lactobacillaceae rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02982 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPCP@1239,3F3Q8@33958,4HAUR@91061,COG0092@1,COG0092@2 NA|NA|NA J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation GOKNOHPG_00567 1423767.BALU01000004_gene1270 4e-54 217.2 Lactobacillaceae rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02890 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6PU@1239,3F6K6@33958,4HIK2@91061,COG0091@1,COG0091@2 NA|NA|NA J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome GOKNOHPG_00568 1423748.BALB01000002_gene325 1.6e-45 188.3 Lactobacillaceae rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02965 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6CX@1239,3F6XP@33958,4HIG0@91061,COG0185@1,COG0185@2 NA|NA|NA J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA GOKNOHPG_00569 405566.lhv_0315 4.7e-154 550.4 Lactobacillaceae rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02886 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TP9X@1239,3F3XI@33958,4HAE8@91061,COG0090@1,COG0090@2 NA|NA|NA J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity GOKNOHPG_00570 326425.lhe_1787 2e-46 191.4 Lactobacillaceae rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02892 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VA4W@1239,3F6Z2@33958,4HKCV@91061,COG0089@1,COG0089@2 NA|NA|NA J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome GOKNOHPG_00571 405566.lhv_0313 3.9e-105 387.5 Lactobacillaceae rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02926,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPGW@1239,3F3QD@33958,4HB01@91061,COG0088@1,COG0088@2 NA|NA|NA J Forms part of the polypeptide exit tunnel GOKNOHPG_00572 1423748.BALB01000002_gene329 7.6e-112 409.8 Lactobacillaceae rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 ko:K02906 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPFT@1239,3F45I@33958,4HAEN@91061,COG0087@1,COG0087@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit GOKNOHPG_00573 1033837.WANG_1903 4.4e-49 200.3 Lactobacillaceae rpsJ GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 ko:K02946 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6C9@1239,3F6KC@33958,4HIKH@91061,COG0051@1,COG0051@2 NA|NA|NA J Involved in the binding of tRNA to the ribosomes GOKNOHPG_00574 405566.lhv_0310 0.0 1364.4 Lactobacillaceae fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02355 ko00000,ko03012,ko03029 Bacteria 1TPF9@1239,3F3JR@33958,4HAB8@91061,COG0480@1,COG0480@2 NA|NA|NA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome GOKNOHPG_00575 1033837.WANG_1901 2.3e-81 308.1 Lactobacillaceae rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02992 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1GG@1239,3F3RX@33958,4H9PA@91061,COG0049@1,COG0049@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA GOKNOHPG_00576 405566.lhv_0308 7.8e-70 269.6 Lactobacillaceae rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02950 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1FJ@1239,3F64B@33958,4HFMZ@91061,COG0048@1,COG0048@2 NA|NA|NA J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit GOKNOHPG_00577 326425.lhe_1794 2.3e-122 444.9 Lactobacillaceae pilD 3.4.23.43 ko:K02236,ko:K02506,ko:K02654 M00331,M00429 ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 Bacteria 1W118@1239,3F863@33958,4HZ6B@91061,COG1989@1,COG1989@2 NA|NA|NA NOU Bacterial Peptidase A24 N-terminal domain GOKNOHPG_00578 891391.LAC30SC_02360 4.8e-29 133.3 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3FCFA@33958,4HC8M@91061,COG2801@1,COG2801@2 NA|NA|NA L COG2963 Transposase and inactivated derivatives GOKNOHPG_00579 891391.LAC30SC_02360 9.2e-57 226.1 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3FCFA@33958,4HC8M@91061,COG2801@1,COG2801@2 NA|NA|NA L COG2963 Transposase and inactivated derivatives GOKNOHPG_00580 891391.LAC30SC_02360 6.2e-61 240.4 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3FCFA@33958,4HC8M@91061,COG2801@1,COG2801@2 NA|NA|NA L COG2963 Transposase and inactivated derivatives GOKNOHPG_00581 405566.lhv_0303 0.0 2418.3 Lactobacillaceae rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TNYT@1239,3F3KF@33958,4HA24@91061,COG0086@1,COG0086@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates GOKNOHPG_00582 405566.lhv_0302 0.0 2356.6 Lactobacillaceae rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TP96@1239,3F4ET@33958,4H9PK@91061,COG0085@1,COG0085@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates GOKNOHPG_00583 326425.lhe_1797 0.0 1525.0 Lactobacillaceae clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 1TPMU@1239,3F3RV@33958,4HACY@91061,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE GOKNOHPG_00584 326425.lhe_1798 1.4e-80 305.4 Lactobacillaceae yebR 1.8.4.14 ko:K08968 ko00270,map00270 R02025 RC00639 ko00000,ko00001,ko01000 Bacteria 1V6GQ@1239,3F6NT@33958,4HH7X@91061,COG1956@1,COG1956@2 NA|NA|NA T GAF domain-containing protein GOKNOHPG_00586 935836.JAEL01000201_gene4586 1.6e-08 63.5 Bacillus Bacteria 1TZQ8@1239,1ZJ4J@1386,2AWWM@1,31NU5@2,4II4F@91061 NA|NA|NA GOKNOHPG_00587 326425.lhe_1801 6.3e-27 126.3 Lactobacillaceae Bacteria 1V7W5@1239,2APNN@1,31ES7@2,3F70U@33958,4HJDN@91061 NA|NA|NA GOKNOHPG_00589 326425.lhe_1803 5.1e-295 1019.6 Lactobacillaceae lysS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP2P@1239,3F439@33958,4H9X4@91061,COG1190@1,COG1190@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family GOKNOHPG_00590 405566.lhv_0298 8e-196 689.5 Lactobacillaceae dus ko:K05540 ko00000,ko01000,ko03016 Bacteria 1TQ2R@1239,3F4C6@33958,4HA9K@91061,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines GOKNOHPG_00591 326425.lhe_1805 1.5e-161 575.5 Lactobacillaceae hslO GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008 ko:K04083 ko00000,ko03110 Bacteria 1TRCH@1239,3F42B@33958,4HAFR@91061,COG1281@1,COG1281@2 NA|NA|NA O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress GOKNOHPG_00592 405566.lhv_0296 0.0 1275.8 Lactobacillaceae ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 ko:K03798 M00742 ko00000,ko00002,ko01000,ko01002,ko03110 Bacteria 1TPTV@1239,3F49Z@33958,4HAJB@91061,COG0465@1,COG0465@2 NA|NA|NA O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins GOKNOHPG_00593 405566.lhv_0295 4.9e-240 836.6 Lactobacillaceae tilS 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 1TPXP@1239,3F4GY@33958,4H9ZM@91061,COG0037@1,COG0037@2 NA|NA|NA J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine GOKNOHPG_00594 326425.lhe_1808 1.5e-59 235.3 Lactobacillaceae yabR ko:K07570,ko:K07571 ko00000 Bacteria 1UI95@1239,3F6P8@33958,4ISGM@91061,COG1098@1,COG1098@2 NA|NA|NA J S1 RNA binding domain GOKNOHPG_00595 405566.lhv_0293 2.6e-59 234.6 Lactobacillaceae divIC ko:K05589,ko:K13052 ko00000,ko03036 Bacteria 1VKC5@1239,3F76Z@33958,4HR53@91061,COG2919@1,COG2919@2 NA|NA|NA D Septum formation initiator GOKNOHPG_00596 326425.lhe_1810 1.8e-34 151.4 Lactobacillaceae yabO GO:0008150,GO:0040007 Bacteria 1VEI5@1239,3F7JX@33958,4HKJJ@91061,COG1188@1,COG1188@2 NA|NA|NA J S4 domain protein GOKNOHPG_00597 405566.lhv_0291 0.0 2243.0 Lactobacillaceae mfd ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPF1@1239,3F4KU@33958,4H9NB@91061,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site GOKNOHPG_00598 405566.lhv_0290 1.1e-103 382.5 Lactobacillaceae pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 1V3NB@1239,3F3VZ@33958,4HH2Z@91061,COG0193@1,COG0193@2 NA|NA|NA J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis GOKNOHPG_00599 405566.lhv_0289 2.1e-182 644.8 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPSY@1239,3F3RM@33958,4HB0Z@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily. LDH family GOKNOHPG_00600 1423748.BALB01000002_gene350 2.7e-126 458.0 Lactobacillaceae Bacteria 1TR5G@1239,3F3JY@33958,4H9ZA@91061,COG0517@1,COG0517@2 NA|NA|NA S (CBS) domain GOKNOHPG_00601 326425.lhe_1815 1.2e-65 255.8 Lactobacillaceae Bacteria 1U689@1239,3F7AB@33958,4IFZ0@91061,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator GOKNOHPG_00602 326425.lhe_1816 1.1e-214 752.3 Lactobacillaceae alr 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011 Bacteria 1TNYY@1239,3F3X2@33958,4HA95@91061,COG0787@1,COG0787@2 NA|NA|NA E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids GOKNOHPG_00603 326425.lhe_1817 1.7e-60 238.4 Lactobacillaceae acpS 2.7.6.3,2.7.8.7,5.1.1.1 ko:K00950,ko:K00997,ko:K01775 ko00473,ko00770,ko00790,ko01100,ko01502,map00473,map00770,map00790,map01100,map01502 M00126,M00841 R00401,R01625,R03503 RC00002,RC00017,RC00285 ko00000,ko00001,ko00002,ko01000,ko01011 iYO844.BSU04620 Bacteria 1VA0T@1239,3F6HC@33958,4HKBI@91061,COG0736@1,COG0736@2 NA|NA|NA I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein GOKNOHPG_00604 326425.lhe_1818 2.3e-244 851.3 Lactobacillaceae cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TPAP@1239,3F46Q@33958,4HAB3@91061,COG0513@1,COG0513@2 NA|NA|NA F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity GOKNOHPG_00605 326425.lhe_1819 5.3e-264 916.4 Lactobacillaceae murF 6.3.2.10,6.3.2.13 ko:K01928,ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R02788,R04573,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1VT78@1239,3F4SK@33958,4HACR@91061,COG0770@1,COG0770@2 NA|NA|NA M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein GOKNOHPG_00606 326425.lhe_1820 1.9e-39 167.9 Lactobacillaceae rpmE2 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEGU@1239,3FCDM@33958,4HNQF@91061,COG0254@1,COG0254@2 NA|NA|NA J Ribosomal protein L31 GOKNOHPG_00607 411465.PEPMIC_00660 7.9e-34 151.0 Bacteria Bacteria COG0778@1,COG0778@2 NA|NA|NA C coenzyme F420-1:gamma-L-glutamate ligase activity GOKNOHPG_00609 411465.PEPMIC_00658 2.1e-36 159.8 Firmicutes Bacteria 1VPX9@1239,2EHRA@1,33BH3@2 NA|NA|NA S YcaO cyclodehydratase, ATP-ad Mg2+-binding GOKNOHPG_00610 999413.HMPREF1094_04658 5.8e-18 98.6 Firmicutes Bacteria 1VP9D@1239,2EU1C@1,33MIE@2 NA|NA|NA S YcaO cyclodehydratase, ATP-ad Mg2+-binding GOKNOHPG_00612 411465.PEPMIC_00655 1.2e-32 147.1 Firmicutes Bacteria 1VI7J@1239,2E6BM@1,330ZD@2 NA|NA|NA GOKNOHPG_00613 405566.lhv_1140 3.4e-209 734.6 Lactobacillaceae ko:K06148 ko00000,ko02000 3.A.1 Bacteria 1UYYQ@1239,3F5DU@33958,4HWP7@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region GOKNOHPG_00615 405566.lhv_0280 3e-153 547.7 Lactobacillaceae Bacteria 1TREF@1239,3F5C1@33958,4H9Y9@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase GOKNOHPG_00616 1033837.WANG_1756 0.0 1407.1 Lactobacillaceae nrdE GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005971,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0015949,GO:0016020,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0051063,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 iAPECO1_1312.APECO1_3846,iYO844.BSU17380 Bacteria 1TPFH@1239,3F3XG@33958,4H9X0@91061,COG0209@1,COG0209@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides GOKNOHPG_00617 1033837.WANG_1755 2.7e-73 281.2 Bacteria nrdI GO:0000166,GO:0003674,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0019538,GO:0032553,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564 ko:K03647 ko00000 Bacteria COG1780@1,COG1780@2 NA|NA|NA F Probably involved in ribonucleotide reductase function GOKNOHPG_00618 1033837.WANG_1754 2.4e-192 677.9 Lactobacillaceae nrdF GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0030145,GO:0032991,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 iECNA114_1301.ECNA114_2708,iECSF_1327.ECSF_2473,iSFV_1184.SFV_2827,iSF_1195.SF2704,iSFxv_1172.SFxv_2966,iS_1188.S2890 Bacteria 1TQTH@1239,3F3P1@33958,4H9WX@91061,COG0208@1,COG0208@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides GOKNOHPG_00619 1400520.LFAB_16000 3.6e-41 174.1 Lactobacillaceae Bacteria 1TRQC@1239,3F4FH@33958,4HD7P@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase GOKNOHPG_00620 525318.HMPREF0497_0232 1.3e-27 129.0 Lactobacillaceae Bacteria 1TRQC@1239,3F4FH@33958,4HD7P@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase GOKNOHPG_00621 1033837.WANG_1753 6.9e-16 89.7 Lactobacillaceae metQ_4 ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1V0Z6@1239,3FC6K@33958,4HBBW@91061,COG1464@1,COG1464@2 NA|NA|NA P Belongs to the nlpA lipoprotein family GOKNOHPG_00622 1423758.BN55_05380 1.2e-20 105.5 Lactobacillaceae Bacteria 1U869@1239,29QIX@1,30BIF@2,3FAKK@33958,4II3T@91061 NA|NA|NA GOKNOHPG_00625 405566.lhv_1909 7.5e-107 393.7 Lactobacillaceae ropB Bacteria 1VD8E@1239,3F61C@33958,4HMD2@91061,COG1396@1,COG1396@2 NA|NA|NA K Transcriptional regulator GOKNOHPG_00626 405566.lhv_1910 3.1e-205 721.1 Lactobacillaceae ko:K07785 ko02020,map02020 ko00000,ko00001,ko02000 2.A.1.31 Bacteria 1UI8U@1239,3FBSV@33958,4ISG9@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator Superfamily GOKNOHPG_00627 405566.lhv_1911 1.7e-151 542.0 Lactobacillaceae ropB Bacteria 1VD8E@1239,3F61C@33958,4HMD2@91061,COG1396@1,COG1396@2 NA|NA|NA K Transcriptional regulator GOKNOHPG_00628 405566.lhv_0511 1.7e-159 568.5 Lactobacillaceae Bacteria 1UZVA@1239,3F4KP@33958,4HH09@91061,COG3039@1,COG3039@2 NA|NA|NA L An automated process has identified a potential problem with this gene model GOKNOHPG_00629 1423780.LOT_0778 2.5e-20 104.8 Lactobacillaceae xylB 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ1I@1239,3FCAE@33958,4HBRJ@91061,COG1070@1,COG1070@2 NA|NA|NA G Xylulose kinase GOKNOHPG_00630 797515.HMPREF9103_01984 3.5e-109 401.0 Lactobacillaceae Bacteria 1V6ES@1239,3F5SD@33958,4HGZI@91061,COG0406@1,COG0406@2 NA|NA|NA G phosphoglycerate mutase GOKNOHPG_00631 797515.HMPREF9103_01983 6.6e-201 706.4 Lactobacillaceae serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP6Y@1239,3F4IU@33958,4HATT@91061,COG1932@1,COG1932@2 NA|NA|NA E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine GOKNOHPG_00632 797515.HMPREF9103_01982 5.5e-209 733.4 Lactobacillaceae serA 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1V410@1239,3F4JJ@33958,4H9PH@91061,COG0111@1,COG0111@2 NA|NA|NA EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family GOKNOHPG_00633 1423754.BALY01000006_gene1368 6.2e-118 430.6 Lactobacillaceae Bacteria 1TQEG@1239,3F43M@33958,4HD6M@91061,COG2801@1,COG2801@2 NA|NA|NA L hmm pf00665 GOKNOHPG_00634 324831.LGAS_1507 5.2e-93 347.4 Lactobacillaceae ko:K07483 ko00000 Bacteria 1V1QC@1239,3F5BG@33958,4HH7E@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain GOKNOHPG_00635 1423780.LOT_0790 8.4e-34 149.8 Lactobacillaceae Bacteria 1VAQZ@1239,3FBPB@33958,4HJFH@91061,COG3548@1,COG3548@2 NA|NA|NA S Protein of unknown function (DUF1211) GOKNOHPG_00636 1033837.WANG_1779 7.2e-99 367.1 Lactobacillaceae Bacteria 1U8KG@1239,29QSS@1,30BSM@2,3FB2Y@33958,4IIIF@91061 NA|NA|NA GOKNOHPG_00637 326425.lhe_0295 1.4e-08 64.3 Lactobacillaceae bioY GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 ko:K03523 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 Bacteria 1V9T0@1239,3FBMX@33958,4HK0R@91061,COG1268@1,COG1268@2 NA|NA|NA S BioY family GOKNOHPG_00638 1033837.WANG_1776 2.2e-187 661.4 Lactobacillaceae birA 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 Bacteria 1TQCU@1239,3F5HY@33958,4HB60@91061,COG0340@1,COG0340@2 NA|NA|NA H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor GOKNOHPG_00639 1033837.WANG_1775 1.1e-133 482.6 Lactobacillaceae fabI GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPVD@1239,3F4AQ@33958,4H9YN@91061,COG0623@1,COG0623@2 NA|NA|NA I Enoyl- acyl-carrier-protein reductase NADH GOKNOHPG_00640 1033837.WANG_1774 7.7e-143 513.1 Lactobacillaceae accA 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHNS@1239,3F496@33958,4HA4C@91061,COG0825@1,COG0825@2 NA|NA|NA I alpha subunit GOKNOHPG_00641 1033837.WANG_1773 3e-156 557.8 Lactobacillaceae accD 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4U@1239,3F3T6@33958,4HAI7@91061,COG0777@1,COG0777@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA GOKNOHPG_00642 1033837.WANG_1772 3.6e-260 903.7 Lactobacillaceae accC GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iSF_1195.SF3294 Bacteria 1TP16@1239,3F3PT@33958,4HARK@91061,COG0439@1,COG0439@2 NA|NA|NA I Acetyl-CoA carboxylase biotin carboxylase subunit GOKNOHPG_00643 1033837.WANG_1771 3.8e-72 277.3 Lactobacillaceae fabZ 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 1VXBZ@1239,3F6TF@33958,4HXVK@91061,COG0764@1,COG0764@2 NA|NA|NA I FabA-like domain GOKNOHPG_00644 1033837.WANG_1770 1.4e-78 298.9 Lactobacillaceae accB 2.3.1.12,4.1.1.3 ko:K00627,ko:K01571,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00217,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 Bacteria 1VAB7@1239,3F7M1@33958,4HKCS@91061,COG0511@1,COG0511@2 NA|NA|NA I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA GOKNOHPG_00645 1033837.WANG_1769 3.8e-229 800.4 Lactobacillaceae fabF 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPA7@1239,3F51H@33958,4H9SD@91061,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP GOKNOHPG_00646 326425.lhe_0286 8.6e-128 463.0 Lactobacillaceae Bacteria 1TP76@1239,3F4RI@33958,4HAA6@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase GOKNOHPG_00647 1033837.WANG_1767 1.7e-168 598.6 Lactobacillaceae fabD 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPB7@1239,3F3W9@33958,4HBCU@91061,COG0331@1,COG0331@2 NA|NA|NA I Malonyl CoA-acyl carrier protein transacylase GOKNOHPG_00648 1033837.WANG_1766 4.9e-35 153.3 Lactobacillaceae acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 1VGIY@1239,3F7ZJ@33958,4HP0V@91061,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis GOKNOHPG_00649 1033837.WANG_1765 3.8e-179 634.0 Lactobacillaceae fabH 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TP0K@1239,3F3XP@33958,4HATK@91061,COG0332@1,COG0332@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids GOKNOHPG_00650 1033837.WANG_1764 1.6e-79 302.0 Lactobacillaceae marR Bacteria 1VCUU@1239,3FC7K@33958,4HIUM@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator GOKNOHPG_00651 1033837.WANG_1763 1.5e-77 295.4 Lactobacillaceae fabZ 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 1V3UN@1239,3FCD6@33958,4HHYD@91061,COG0764@1,COG0764@2 NA|NA|NA I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs GOKNOHPG_00652 326425.lhe_0280 7.9e-91 339.7 Lactobacillaceae pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 R01570,R01876,R02296,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 iHN637.CLJU_RS08925 Bacteria 1TPCH@1239,3F45P@33958,4H9NP@91061,COG0213@1,COG0213@2 NA|NA|NA F pyrimidine-nucleoside phosphorylase GOKNOHPG_00653 1423748.BALB01000014_gene1334 2.7e-21 107.5 Lactobacillaceae XK27_06780 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPHU@1239,3F4HF@33958,4HA2C@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease GOKNOHPG_00654 1423748.BALB01000014_gene1334 2.1e-56 224.9 Lactobacillaceae XK27_06780 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPHU@1239,3F4HF@33958,4HA2C@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease GOKNOHPG_00655 326425.lhe_0212 3.3e-36 157.1 Lactobacillaceae Bacteria 1U6A1@1239,2C9N2@1,30A73@2,3F7ES@33958,4IG19@91061 NA|NA|NA GOKNOHPG_00656 405566.lhv_2052 1.3e-285 988.4 Lactobacillaceae ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03328,ko:K06409 ko00000,ko02000 2.A.66.2,2.A.66.2.14 Bacteria 1TNYX@1239,3F404@33958,4H9RY@91061,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein GOKNOHPG_00657 1423748.BALB01000014_gene1337 2.9e-147 528.1 Lactobacillaceae lysA2 ko:K07273 ko00000 Bacteria 1VF8D@1239,3F4U9@33958,4HX0U@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 GOKNOHPG_00658 326425.lhe_0209 7.4e-118 429.9 Lactobacillaceae Bacteria 1V6FC@1239,3FBKG@33958,4HPG8@91061,COG5523@1,COG5523@2 NA|NA|NA S Protein of unknown function (DUF975) GOKNOHPG_00659 326425.lhe_0207 6.3e-48 196.8 Lactobacillaceae Bacteria 1U6PF@1239,29PJF@1,30AHK@2,3F894@33958,4IGGE@91061 NA|NA|NA GOKNOHPG_00660 324831.LGAS_0137 2.8e-17 94.7 Lactobacillaceae Bacteria 1U65S@1239,2CHFN@1,30A3Z@2,3F74U@33958,4IFVM@91061 NA|NA|NA GOKNOHPG_00661 326425.lhe_0205 4.6e-118 430.6 Lactobacillaceae ko:K07052 ko00000 Bacteria 1VNA9@1239,3F5T9@33958,4HRMP@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity GOKNOHPG_00662 97137.C821_01144 1.2e-10 72.0 Lactobacillaceae Bacteria 1U5GX@1239,2DKJE@1,309Q1@2,3F5X8@33958,4IF7Q@91061 NA|NA|NA GOKNOHPG_00664 1423748.BALB01000014_gene1342 2.7e-174 617.8 Lactobacillaceae pbpX2 ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1V0GX@1239,3F4TH@33958,4HCXH@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase GOKNOHPG_00665 326425.lhe_0203 3.6e-246 857.1 Lactobacillaceae dltD ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1TSZU@1239,3F3WE@33958,4HC3H@91061,COG3966@1,COG3966@2 NA|NA|NA M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) GOKNOHPG_00666 326425.lhe_0202 5.7e-36 156.4 Lactobacillaceae dltC GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K02078,ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1VFQI@1239,3F7Q1@33958,4HNIH@91061,COG0236@1,COG0236@2 NA|NA|NA J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall GOKNOHPG_00667 405566.lhv_2059 2.9e-240 837.4 Lactobacillaceae dltB ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1TP52@1239,3F4KK@33958,4HBQG@91061,COG1696@1,COG1696@2 NA|NA|NA M MBOAT, membrane-bound O-acyltransferase family GOKNOHPG_00668 326425.lhe_0200 4.8e-290 1003.0 Lactobacillaceae dltA 6.1.1.13 ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1TPTH@1239,3F49R@33958,4HAHU@91061,COG1020@1,COG1020@2 NA|NA|NA H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall GOKNOHPG_00669 525365.HMPREF0548_1419 7e-19 99.0 Lactobacillaceae Bacteria 1U6IK@1239,2DKQV@1,30ADX@2,3F7ZM@33958,4IGAZ@91061 NA|NA|NA S D-Ala-teichoic acid biosynthesis protein GOKNOHPG_00670 326425.lhe_0198 3.8e-50 203.8 Lactobacillaceae Bacteria 1U67F@1239,29P6X@1,30A50@2,3F78Y@33958,4IFXY@91061 NA|NA|NA GOKNOHPG_00671 326425.lhe_0197 8.8e-212 742.7 Lactobacillaceae ywhK Bacteria 1V841@1239,3F50M@33958,4HITC@91061,COG3391@1,COG3391@2 NA|NA|NA S Membrane GOKNOHPG_00672 1423748.BALB01000014_gene1349 3.9e-81 307.4 Lactobacillaceae ykuL Bacteria 1V9HN@1239,3F678@33958,4HH3X@91061,COG0517@1,COG0517@2 NA|NA|NA S (CBS) domain GOKNOHPG_00673 405566.lhv_2064 0.0 1141.3 Lactobacillaceae cadA Bacteria 1TQ07@1239,3F4JI@33958,4H9SP@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase GOKNOHPG_00674 405566.lhv_2065 1e-202 712.6 Lactobacillaceae napA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 Bacteria 1TS32@1239,3FCEG@33958,4HP0X@91061,COG0475@1,COG0475@2 NA|NA|NA P Sodium/hydrogen exchanger family GOKNOHPG_00675 1423748.BALB01000014_gene1354 4.4e-49 200.3 Lactobacillaceae yefM 2.3.1.15 ko:K08591,ko:K19158,ko:K19159 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004,ko02048 Bacteria 1U6UC@1239,3F8I1@33958,4IGN6@91061,COG2161@1,COG2161@2 NA|NA|NA D Antitoxin component of a toxin-antitoxin (TA) module GOKNOHPG_00676 405566.lhv_2907 1.6e-47 194.9 Lactobacillaceae ko:K19158 ko00000,ko01000,ko02048 Bacteria 1VEN0@1239,3F80N@33958,4HRVW@91061,COG4115@1,COG4115@2 NA|NA|NA S YoeB-like toxin of bacterial type II toxin-antitoxin system GOKNOHPG_00677 405566.lhv_2067 3.2e-281 973.8 Lactobacillaceae ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TSRV@1239,3F3JJ@33958,4HIAU@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region GOKNOHPG_00678 326425.lhe_1895 1.8e-78 298.9 Lactobacillaceae Bacteria 1VKFR@1239,3F701@33958,4HKWD@91061,COG3595@1,COG3595@2 NA|NA|NA S Putative adhesin GOKNOHPG_00679 326425.lhe_1896 8.5e-151 539.7 Lactobacillaceae mutR ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria 1U54X@1239,3F4P7@33958,4IEW2@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins GOKNOHPG_00680 326425.lhe_1897 1.6e-45 188.3 Lactobacillaceae Bacteria 1U6UW@1239,2BRU7@1,32KUC@2,3F8IR@33958,4IGNS@91061 NA|NA|NA GOKNOHPG_00681 326425.lhe_1898 1.2e-117 429.1 Lactobacillaceae ko:K07052 ko00000 Bacteria 1VFRX@1239,3F4Q0@33958,4HRQQ@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity GOKNOHPG_00682 326425.lhe_1899 2.7e-78 298.1 Lactobacillaceae Bacteria 1V8H4@1239,3FC81@33958,4HI4B@91061,COG1434@1,COG1434@2 NA|NA|NA S DUF218 domain GOKNOHPG_00683 1423748.BALB01000021_gene1667 1.4e-309 1068.1 Lactobacillaceae macB_3 ko:K02003,ko:K02004,ko:K05685 ko02010,map02010 M00258,M00709 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 Bacteria 1TPBJ@1239,3F44P@33958,4HBK7@91061,COG0577@1,COG0577@2,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein GOKNOHPG_00684 405566.lhv_2075 1.6e-95 355.5 Lactobacillaceae Bacteria 1V2ZW@1239,3FBM9@33958,4IR4I@91061,COG4684@1,COG4684@2 NA|NA|NA S ECF transporter, substrate-specific component GOKNOHPG_00685 326425.lhe_1902 1.7e-159 568.5 Lactobacillaceae yeaE Bacteria 1TPM1@1239,3FB4R@33958,4HU74@91061,COG0656@1,COG0656@2 NA|NA|NA S Aldo/keto reductase family GOKNOHPG_00686 405566.lhv_2077 1.7e-131 475.3 Lactobacillaceae nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0008150,GO:0008152,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135 3.1.1.31,3.5.99.6 ko:K01057,ko:K02564 ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R00765,R02035 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP10@1239,3F3NR@33958,4HAG4@91061,COG0363@1,COG0363@2 NA|NA|NA G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion GOKNOHPG_00687 748671.LCRIS_01642 6.4e-26 123.2 Lactobacillaceae ybbH_2 ko:K03481 ko00000,ko03000 Bacteria 1TR0N@1239,3F42G@33958,4HB9E@91061,COG1737@1,COG1737@2 NA|NA|NA K rpiR family GOKNOHPG_00688 326425.lhe_0477 0.0 1255.4 Lactobacillaceae ydgH GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006790,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0030312,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046505,GO:0046506,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901576 ko:K06994,ko:K07003 ko00000 Bacteria 1TQ7C@1239,3FCCY@33958,4HBM6@91061,COG1511@1,COG1511@2,COG2409@1,COG2409@2 NA|NA|NA S MMPL family GOKNOHPG_00689 405566.lhv_1742 3.3e-98 364.4 Lactobacillaceae yobS GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 Bacteria 1V1DM@1239,3F5CS@33958,4HG0Y@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family GOKNOHPG_00690 326425.lhe_0475 1e-157 562.8 Lactobacillaceae 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1U564@1239,3F4WE@33958,4IEXG@91061,COG2367@1,COG2367@2 NA|NA|NA V Beta-lactamase enzyme family GOKNOHPG_00691 405566.lhv_1744 3.5e-158 564.3 Lactobacillaceae corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1TPSV@1239,3FCA3@33958,4HAPC@91061,COG0598@1,COG0598@2 NA|NA|NA P CorA-like Mg2+ transporter protein GOKNOHPG_00692 326425.lhe_0473 3.7e-230 803.9 Lactobacillaceae ko:K02027,ko:K05813 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 Bacteria 1TS64@1239,3F4P5@33958,4HEKH@91061,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein GOKNOHPG_00693 405566.lhv_1747 2.1e-254 884.4 Lactobacillaceae YSH1 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1UDEF@1239,3F4WJ@33958,4HIN2@91061,COG0595@1,COG0595@2 NA|NA|NA S Zn-dependent metallo-hydrolase RNA specificity domain GOKNOHPG_00694 326425.lhe_0471 1.1e-144 519.2 Lactobacillaceae gtsC ko:K02026 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 1TRCP@1239,3FC8G@33958,4HBK1@91061,COG0395@1,COG0395@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component GOKNOHPG_00695 405566.lhv_1749 7.3e-158 563.1 Lactobacillaceae gtsB ko:K02025,ko:K15771 ko02010,map02010 M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2 Bacteria 1TREE@1239,3F464@33958,4HCD0@91061,COG1175@1,COG1175@2 NA|NA|NA P ABC-type sugar transport systems, permease components GOKNOHPG_00696 405566.lhv_1750 1.9e-200 704.9 Lactobacillaceae malK ko:K10112,ko:K17240 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00599,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.38 iLJ478.TM0421 Bacteria 1TP2M@1239,3FC3J@33958,4HBKK@91061,COG3842@1,COG3842@2 NA|NA|NA P ATPases associated with a variety of cellular activities GOKNOHPG_00697 405566.lhv_1751 5.5e-280 969.5 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase GOKNOHPG_00698 326425.lhe_0467 6.1e-157 560.1 Lactobacillaceae endA ko:K15051 ko00000 Bacteria 1V4X2@1239,3F3Y8@33958,4HIF5@91061,COG2169@1,COG2169@2 NA|NA|NA F DNA RNA non-specific endonuclease GOKNOHPG_00699 405566.lhv_1753 7e-162 576.6 Lactobacillaceae dnaQ 2.7.7.7 ko:K02342,ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TRS5@1239,3F546@33958,4HFJA@91061,COG2176@1,COG2176@2 NA|NA|NA L EXOIII GOKNOHPG_00700 326425.lhe_0465 4e-158 563.9 Lactobacillaceae Bacteria 1V192@1239,3F52D@33958,4IQTP@91061,COG0846@1,COG0846@2 NA|NA|NA K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form GOKNOHPG_00701 1033837.WANG_1224 1.8e-105 388.7 Lactobacillaceae yviA Bacteria 1TPNF@1239,3F4F3@33958,4HF15@91061,COG2323@1,COG2323@2 NA|NA|NA S Protein of unknown function (DUF421) GOKNOHPG_00702 405566.lhv_1756 5.4e-64 250.4 Lactobacillaceae Bacteria 1VG8C@1239,2C9NT@1,32ZGB@2,3F749@33958,4HN0V@91061 NA|NA|NA S Protein of unknown function (DUF3290) GOKNOHPG_00703 326425.lhe_0463 8.4e-139 499.6 Lactobacillaceae pnuC ko:K03811 ko00000,ko02000 4.B.1.1 Bacteria 1VE5T@1239,3F3MB@33958,4HMNW@91061,COG3201@1,COG3201@2 NA|NA|NA H nicotinamide mononucleotide transporter GOKNOHPG_00704 1423748.BALB01000051_gene2072 7.7e-12 75.9 Lactobacillaceae Bacteria 1VNWP@1239,2DBU6@1,2ZB4C@2,3F51G@33958,4HRN6@91061 NA|NA|NA GOKNOHPG_00705 1423748.BALB01000015_gene1366 2.8e-94 351.3 Lactobacillaceae Bacteria 1UI8X@1239,3FBSZ@33958,4ISGE@91061,COG2461@1,COG2461@2 NA|NA|NA S PAS domain GOKNOHPG_00706 405566.lhv_1758 1.3e-272 945.3 Lactobacillaceae ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TSRV@1239,3F3JJ@33958,4HIAU@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region GOKNOHPG_00707 1423748.BALB01000015_gene1369 2.7e-179 634.4 Lactobacillaceae pip 3.4.11.5 ko:K01259 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 1UEDT@1239,3F47H@33958,4HF61@91061,COG2267@1,COG2267@2 NA|NA|NA E Releases the N-terminal proline from various substrates GOKNOHPG_00708 326425.lhe_0460 3.9e-187 660.6 Lactobacillaceae add 3.5.4.4 ko:K01488 ko00230,ko01100,ko05340,map00230,map01100,map05340 R01560,R02556 RC00477 ko00000,ko00001,ko01000 iHN637.CLJU_RS13960 Bacteria 1U44B@1239,3F5RC@33958,4HCES@91061,COG1816@1,COG1816@2 NA|NA|NA F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism GOKNOHPG_00709 326425.lhe_0459 3.3e-94 350.9 Lactobacillaceae Bacteria 1V8XI@1239,3FBAU@33958,4HJ7M@91061,COG3613@1,COG3613@2 NA|NA|NA F Nucleoside 2-deoxyribosyltransferase GOKNOHPG_00710 1423748.BALB01000015_gene1372 3.3e-67 261.5 Lactobacillaceae Bacteria 1VD0Q@1239,3FBE6@33958,4IPQG@91061,COG3212@1,COG3212@2 NA|NA|NA S Peptidase propeptide and YPEB domain GOKNOHPG_00711 1423748.BALB01000015_gene1373 3.1e-53 214.2 Lactobacillaceae paiA 2.3.1.57 ko:K22441 ko00000,ko01000 Bacteria 1VDFK@1239,3FB81@33958,4HMHW@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain GOKNOHPG_00712 1423748.BALB01000015_gene1375 7.8e-14 82.4 Lactobacillaceae Bacteria 1U5TJ@1239,3F6H2@33958,4IFHH@91061,COG3212@1,COG3212@2 NA|NA|NA S Peptidase propeptide and YPEB domain GOKNOHPG_00713 326425.lhe_0458 5.5e-50 203.4 Lactobacillaceae Bacteria 1U5TJ@1239,3F6H2@33958,4IFHH@91061,COG3212@1,COG3212@2 NA|NA|NA S Peptidase propeptide and YPEB domain GOKNOHPG_00714 405566.lhv_1764 2e-244 851.3 Lactobacillaceae ko:K02027,ko:K05813 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 Bacteria 1TS64@1239,3F4P5@33958,4HEKH@91061,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein GOKNOHPG_00715 405566.lhv_1765 1.4e-98 365.5 Lactobacillaceae efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 1TR8P@1239,3F4EW@33958,4H9YX@91061,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase GOKNOHPG_00716 326425.lhe_0455 8.7e-170 602.8 Lactobacillaceae coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECDH1ME8569_1439.ECDH1ME8569_3838,iECH74115_1262.ECH74115_5439,iECSE_1348.ECSE_4265,iECSF_1327.ECSF_3833,iECSP_1301.ECSP_5045,iECW_1372.ECW_m4332,iEcDH1_1363.EcDH1_4016,iEcolC_1368.EcolC_4046,iPC815.YPO3758,iSFV_1184.SFV_4047,iSFxv_1172.SFxv_4418,iWFL_1372.ECW_m4332,iZ_1308.Z5545 Bacteria 1TPHJ@1239,3F42Q@33958,4HA4K@91061,COG1072@1,COG1072@2 NA|NA|NA F Pantothenic acid kinase GOKNOHPG_00717 405566.lhv_1767 4.3e-103 380.6 Lactobacillaceae Bacteria 1VB88@1239,3F5AR@33958,4IPQF@91061,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase GOKNOHPG_00718 405566.lhv_1910 6.9e-155 553.5 Lactobacillaceae ko:K07785 ko02020,map02020 ko00000,ko00001,ko02000 2.A.1.31 Bacteria 1UI8U@1239,3FBSV@33958,4ISG9@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator Superfamily GOKNOHPG_00719 405566.lhv_1910 1.1e-34 152.1 Lactobacillaceae ko:K07785 ko02020,map02020 ko00000,ko00001,ko02000 2.A.1.31 Bacteria 1UI8U@1239,3FBSV@33958,4ISG9@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator Superfamily GOKNOHPG_00720 405566.lhv_1911 1.9e-53 215.3 Lactobacillaceae ropB Bacteria 1VD8E@1239,3F61C@33958,4HMD2@91061,COG1396@1,COG1396@2 NA|NA|NA K Transcriptional regulator GOKNOHPG_00721 405566.lhv_1901 4.5e-219 766.9 Lactobacillaceae ko:K07493 ko00000 Bacteria 1TP4C@1239,3F4RA@33958,4HAXJ@91061,COG3328@1,COG3328@2 NA|NA|NA L Transposase GOKNOHPG_00722 1423754.BALY01000059_gene700 7e-67 261.5 Lactobacillaceae Bacteria 1V8VU@1239,3F45C@33958,4HWIQ@91061,COG5527@1,COG5527@2 NA|NA|NA L Initiator Replication protein GOKNOHPG_00723 525309.HMPREF0494_1294 3e-28 131.0 Lactobacillaceae ko:K07473 ko00000,ko02048 Bacteria 1W2DP@1239,28XQA@1,2ZJM1@2,3F7TV@33958,4IG7X@91061 NA|NA|NA S RelB antitoxin GOKNOHPG_00724 525309.HMPREF0494_2047 2.8e-42 177.9 Lactobacillaceae Bacteria 1U6NH@1239,29PJ0@1,30AH5@2,3F876@33958,4IGFG@91061 NA|NA|NA GOKNOHPG_00725 1423807.BACO01000085_gene2462 5.4e-07 60.5 Lactobacillaceae Bacteria 1U74C@1239,29PW5@1,30AUG@2,3F8YJ@33958,4IGYZ@91061 NA|NA|NA S Family of unknown function (DUF5388) GOKNOHPG_00726 1423807.BACO01000085_gene2463 9.3e-91 340.1 Lactobacillaceae soj ko:K03496 ko00000,ko03036,ko04812 Bacteria 1TP8S@1239,3F4QA@33958,4HCBZ@91061,COG1192@1,COG1192@2 NA|NA|NA D CobQ CobB MinD ParA nucleotide binding domain protein GOKNOHPG_00727 1423758.BN55_09605 2.2e-32 144.4 Lactobacillaceae Bacteria 1TU4U@1239,3F8GD@33958,4IGM3@91061,COG2161@1,COG2161@2 NA|NA|NA D Antitoxin component of a toxin-antitoxin (TA) module GOKNOHPG_00728 1423758.BN55_09600 2.2e-35 154.8 Lactobacillaceae Bacteria 1U8HE@1239,2BUB1@1,32PKN@2,3FAZN@33958,4IIFA@91061 NA|NA|NA GOKNOHPG_00729 326425.lhe_0313 3.5e-259 900.6 Lactobacillaceae Bacteria 1TSRV@1239,3F46B@33958,4HCIZ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC-type multidrug transport system, ATPase and permease components GOKNOHPG_00730 326425.lhe_0314 4.8e-277 959.9 Lactobacillaceae Bacteria 1TSRV@1239,3F46B@33958,4HCIZ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC-type multidrug transport system, ATPase and permease components GOKNOHPG_00732 97137.C821_01939 2.1e-09 68.2 Bacilli Bacteria 1VKCM@1239,2DR42@1,33A2M@2,4HRAS@91061 NA|NA|NA S Protein of unknown function (DUF2922) GOKNOHPG_00733 891391.LAC30SC_10905 1.4e-37 162.2 Lactobacillaceae ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 1W2GV@1239,3F8DK@33958,4IGJ6@91061,COG0629@1,COG0629@2 NA|NA|NA L Single-strand binding protein family GOKNOHPG_00734 713605.ADHG01000001_gene353 1.4e-21 109.4 Lactobacillaceae ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 1W2GV@1239,3F8DK@33958,4IGJ6@91061,COG0629@1,COG0629@2 NA|NA|NA L Single-strand binding protein family GOKNOHPG_00735 1133569.AHYZ01000019_gene565 7.2e-101 373.2 Lactobacillaceae tnpR Bacteria 1UZM8@1239,3FBG8@33958,4IQ67@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain GOKNOHPG_00737 641146.HMPREF9020_01129 5.4e-34 150.2 Bacteria Bacteria COG0640@1,COG0640@2 NA|NA|NA K DNA-binding transcription factor activity GOKNOHPG_00739 1423816.BACQ01000069_gene2568 1.6e-55 221.9 Lactobacillaceae tnp2PF3 Bacteria 1VXWA@1239,3F7AF@33958,4HXG3@91061,COG3293@1,COG3293@2 NA|NA|NA L Transposase DDE domain GOKNOHPG_00740 1122149.BACN01000095_gene1995 8.6e-53 212.6 Lactobacillaceae tnp2PF3 Bacteria 1U5ZT@1239,3F6RW@33958,4IFNT@91061,COG3293@1,COG3293@2 NA|NA|NA L Putative transposase of IS4/5 family (DUF4096) GOKNOHPG_00742 405566.lhv_1986 1.4e-167 595.5 Lactobacillaceae Bacteria 1UIWH@1239,3F5HW@33958,4HI23@91061,COG0524@1,COG0524@2 NA|NA|NA G Belongs to the carbohydrate kinase PfkB family GOKNOHPG_00743 405566.lhv_1985 8.2e-249 865.9 Bacilli ko:K03457 ko00000 2.A.39 Bacteria 1TRAH@1239,4IRPE@91061,COG1457@1,COG1457@2 NA|NA|NA F Belongs to the purine-cytosine permease (2.A.39) family GOKNOHPG_00744 405566.lhv_1984 3.6e-188 664.1 Lactobacillaceae yegU Bacteria 1U2AQ@1239,3F4WI@33958,4HIXT@91061,COG1397@1,COG1397@2 NA|NA|NA O ADP-ribosylglycohydrolase GOKNOHPG_00745 525367.HMPREF0556_11469 1.4e-61 242.7 Listeriaceae hsdS_1 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1TP5N@1239,26KX7@186820,4HN7V@91061,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain GOKNOHPG_00746 1423780.LOT_2221 0.0 1257.7 Lactobacillaceae Bacteria 1VQWC@1239,3F4DP@33958,4HD6B@91061,COG0507@1,COG0507@2 NA|NA|NA L MobA MobL family protein GOKNOHPG_00747 908339.HMPREF9265_1193 3.6e-26 123.6 Lactobacillaceae Bacteria 1U69C@1239,29P8B@1,30A6E@2,3F7CM@33958,4IG0H@91061 NA|NA|NA GOKNOHPG_00748 1033837.WANG_1719 2e-40 171.4 Lactobacillaceae Bacteria 1VKZC@1239,2EJES@1,33D5R@2,3F6Y2@33958,4HRGI@91061 NA|NA|NA GOKNOHPG_00749 908339.HMPREF9265_1769 5.6e-58 230.3 Lactobacillaceae Bacteria 1V4U7@1239,3F5H8@33958,4HHGF@91061,COG4185@1,COG4185@2 NA|NA|NA S protein conserved in bacteria GOKNOHPG_00750 1122149.BACN01000133_gene193 2.9e-27 127.1 Lactobacillaceae Bacteria 1U6EI@1239,2DKQ6@1,30AAQ@2,3F7QK@33958,4IG69@91061 NA|NA|NA GOKNOHPG_00751 1423734.JCM14202_2806 1.6e-42 178.3 Lactobacillaceae relB ko:K07473 ko00000,ko02048 Bacteria 1VGJW@1239,3F72D@33958,4HR7A@91061,COG3077@1,COG3077@2 NA|NA|NA L Addiction module antitoxin, RelB DinJ family GOKNOHPG_00753 326425.lhe_0789 3.1e-78 297.7 Lactobacillaceae usp6 ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1V3NY@1239,3F68T@33958,4HIP3@91061,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein GOKNOHPG_00754 326425.lhe_0788 9.5e-217 759.2 Lactobacillaceae rodA ko:K05837 ko00000,ko03036 Bacteria 1TPGH@1239,3F4J4@33958,4HAV4@91061,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family GOKNOHPG_00755 326425.lhe_0787 7.3e-33 146.0 Lactobacillaceae Bacteria 1U6BQ@1239,29FEW@1,302CK@2,3F7J3@33958,4IG3B@91061 NA|NA|NA S Protein of unknown function (DUF2969) GOKNOHPG_00756 405566.lhv_2403 3.8e-50 203.8 Lactobacillaceae yidD ko:K08998 ko00000 Bacteria 1VEIG@1239,3F7H1@33958,4HPA3@91061,COG0759@1,COG0759@2 NA|NA|NA S Could be involved in insertion of integral membrane proteins into the membrane GOKNOHPG_00757 1423748.BALB01000001_gene90 1.9e-178 631.7 Lactobacillaceae mbl ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 1TP51@1239,3F463@33958,4HA4S@91061,COG1077@1,COG1077@2 NA|NA|NA D Cell shape determining protein MreB Mrl GOKNOHPG_00758 405566.lhv_2402 5.8e-30 136.3 Lactobacillaceae ywzB Bacteria 1U2FQ@1239,3F831@33958,4HNZX@91061,COG4836@1,COG4836@2 NA|NA|NA S Protein of unknown function (DUF1146) GOKNOHPG_00759 748671.LCRIS_00772 4.6e-60 237.3 Lactobacillaceae atpC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190 Bacteria 1VA89@1239,3F6I6@33958,4HKHS@91061,COG0355@1,COG0355@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane GOKNOHPG_00760 326425.lhe_0782 1.2e-237 828.9 Lactobacillaceae atpD 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iSB619.SA_RS10965 Bacteria 1TPGF@1239,3F3TF@33958,4HAT6@91061,COG0055@1,COG0055@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits GOKNOHPG_00761 326425.lhe_0781 7e-170 603.2 Lactobacillaceae atpG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611,iSB619.SA_RS10970,iYO844.BSU36820 Bacteria 1TPBX@1239,3F40E@33958,4HB0E@91061,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex GOKNOHPG_00762 405566.lhv_0810 4.8e-282 976.5 Lactobacillaceae atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 Bacteria 1TNZ8@1239,3F3R4@33958,4HAMZ@91061,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit GOKNOHPG_00763 405566.lhv_0809 2.2e-91 341.7 Lactobacillaceae atpH GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 1VAG3@1239,3F5TZ@33958,4HKFW@91061,COG0712@1,COG0712@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation GOKNOHPG_00764 1423748.BALB01000001_gene98 1.1e-49 203.0 Lactobacillaceae atpF ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iHN637.CLJU_RS01170,iYO844.BSU36850 Bacteria 1VB85@1239,3F5M8@33958,4HM64@91061,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) GOKNOHPG_00765 1423748.BALB01000001_gene99 3.5e-27 127.1 Lactobacillaceae atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 1VEHP@1239,3F82A@33958,4HNKQ@91061,COG0636@1,COG0636@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation GOKNOHPG_00766 326425.lhe_0776 2.1e-126 458.4 Lactobacillaceae atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666 Bacteria 1TQIT@1239,3F3RE@33958,4H9NV@91061,COG0356@1,COG0356@2 NA|NA|NA C it plays a direct role in the translocation of protons across the membrane GOKNOHPG_00767 326425.lhe_0775 8.8e-113 412.9 Lactobacillaceae upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000 iSB619.SA_RS11010 Bacteria 1TPMT@1239,3F4M0@33958,4H9Y0@91061,COG0035@1,COG0035@2 NA|NA|NA F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate GOKNOHPG_00768 326425.lhe_0774 4.6e-188 663.7 Lactobacillaceae ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87,3.1.3.48 ko:K01104,ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 1TP1I@1239,3F3T1@33958,4HA7W@91061,COG0009@1,COG0009@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine GOKNOHPG_00769 326425.lhe_0773 5.6e-155 553.5 Lactobacillaceae prmB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564 2.1.1.297,2.1.1.298 ko:K02493,ko:K07320 R10806 RC00003,RC03279 ko00000,ko01000,ko03009,ko03012 Bacteria 1TSMA@1239,3F460@33958,4HC6W@91061,COG2890@1,COG2890@2 NA|NA|NA J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif GOKNOHPG_00770 326425.lhe_0772 6.9e-182 643.3 Lactobacillaceae prfA ko:K02835 ko00000,ko03012 Bacteria 1TQ7V@1239,3F3Q0@33958,4H9MB@91061,COG0216@1,COG0216@2 NA|NA|NA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA GOKNOHPG_00771 326425.lhe_0771 2.2e-113 414.8 Lactobacillaceae tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 iAF1260.b1238,iBWG_1329.BWG_1065,iECDH10B_1368.ECDH10B_1298,iECDH1ME8569_1439.ECDH1ME8569_1176,iEcDH1_1363.EcDH1_2411,iJO1366.b1238,iJR904.b1238,iPC815.YPO2176,iY75_1357.Y75_RS06470 Bacteria 1TRVM@1239,3F4UE@33958,4HA4A@91061,COG1435@1,COG1435@2 NA|NA|NA F thymidine kinase GOKNOHPG_00772 405566.lhv_0800 1.3e-246 858.6 Lactobacillaceae murF 6.3.2.10,6.3.2.13 ko:K01928,ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R02788,R04573,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TRG9@1239,3FBS5@33958,4HAMY@91061,COG0770@1,COG0770@2 NA|NA|NA M Domain of unknown function (DUF1727) GOKNOHPG_00775 326425.lhe_0757 5.6e-194 683.3 Lactobacillaceae ampC Bacteria 1TNZX@1239,3F3WZ@33958,4IPJT@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase GOKNOHPG_00776 272621.LBA0753 6.7e-206 723.4 Lactobacillaceae ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1UYQB@1239,3F3NG@33958,4HE3Y@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GOKNOHPG_00777 326425.lhe_0755 1.2e-260 905.2 Lactobacillaceae pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 iLJ478.TM1385 Bacteria 1TP29@1239,3F3XK@33958,4H9VI@91061,COG0166@1,COG0166@2 NA|NA|NA G Belongs to the GPI family GOKNOHPG_00778 326425.lhe_0754 3.2e-107 394.4 Lactobacillaceae vanZ Bacteria 1VK3A@1239,3F5EN@33958,4HPCD@91061,COG4767@1,COG4767@2 NA|NA|NA V VanZ like family GOKNOHPG_00779 326425.lhe_0753 0.0 1380.9 Lactobacillaceae ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 R05081,R10849 RC00017 ko00000,ko00001,ko01000 Bacteria 1TRMA@1239,3F3R7@33958,4H9S0@91061,COG1368@1,COG1368@2 NA|NA|NA M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily GOKNOHPG_00780 405566.lhv_0791 8.2e-271 939.1 Lactobacillaceae yclK 2.7.13.3 ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQ1H@1239,3FBSR@33958,4IS6U@91061,COG5000@1,COG5000@2,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase GOKNOHPG_00781 405566.lhv_0790 1e-128 466.1 Lactobacillaceae Bacteria 1TPZ0@1239,3FC92@33958,4HA7D@91061,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C terminal GOKNOHPG_00782 326425.lhe_0750 9.2e-60 236.1 Lactobacillaceae Bacteria 1VKM4@1239,2ZY3R@2,3F6IB@33958,4I0CM@91061,COG5658@1 NA|NA|NA S SdpI/YhfL protein family GOKNOHPG_00783 326425.lhe_0749 1.4e-165 589.0 Lactobacillaceae manA 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 1VRGI@1239,3F40I@33958,4HBFW@91061,COG1482@1,COG1482@2 NA|NA|NA G mannose-6-phosphate isomerase GOKNOHPG_00784 405566.lhv_0788 3.7e-148 530.8 Lactobacillaceae patB 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 Bacteria 1TP5G@1239,3F4JX@33958,4H9PE@91061,COG1168@1,COG1168@2 NA|NA|NA E Aminotransferase, class I GOKNOHPG_00785 748671.LCRIS_00747 2.4e-31 141.4 Lactobacillaceae Bacteria 1TQXN@1239,3F4Y5@33958,4HBHT@91061,COG5434@1,COG5434@2 NA|NA|NA M Protein of unknown function (DUF3737) GOKNOHPG_00786 748671.LCRIS_01023 2.4e-154 552.4 Lactobacillaceae Bacteria 1TSRV@1239,3F3JJ@33958,4HIAU@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region GOKNOHPG_00788 1423748.BALB01000021_gene1657 6.7e-224 783.1 Lactobacillaceae pbuG ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 1TQC6@1239,3F44D@33958,4HANG@91061,COG2252@1,COG2252@2 NA|NA|NA S permease GOKNOHPG_00789 326425.lhe_1914 2.3e-35 154.5 Lactobacillaceae Bacteria 1U6NN@1239,29PJ2@1,30AH7@2,3F87H@33958,4IGFM@91061 NA|NA|NA GOKNOHPG_00790 326425.lhe_1915 3.9e-75 287.3 Lactobacillaceae atkY Bacteria 1V7EY@1239,3FBNQ@33958,4HP8S@91061,COG3682@1,COG3682@2 NA|NA|NA K Penicillinase repressor GOKNOHPG_00791 326425.lhe_1916 6.6e-63 246.5 Lactobacillaceae silP 1.9.3.1,3.6.3.54 ko:K02275,ko:K17686 ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016 M00155 R00081,R00086 RC00002,RC00016 ko00000,ko00001,ko00002,ko01000 3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 1TQ02@1239,3FBQA@33958,4IRVT@91061,COG4633@1,COG4633@2 NA|NA|NA S Cupredoxin-like domain GOKNOHPG_00792 326425.lhe_1917 5.4e-49 199.9 Lactobacillaceae silP 1.9.3.1,3.6.3.54 ko:K02275,ko:K17686 ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016 M00155 R00081,R00086 RC00002,RC00016 ko00000,ko00001,ko00002,ko01000 3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 1U632@1239,3F6XB@33958,4IFSB@91061,COG4633@1,COG4633@2 NA|NA|NA S Cupredoxin-like domain GOKNOHPG_00793 405566.lhv_2097 0.0 1169.5 Lactobacillaceae copA 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 1TP5S@1239,3F4IX@33958,4HAI0@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase GOKNOHPG_00794 1545701.LACWKB10_0382 1.2e-27 129.4 Lactobacillaceae mutT Bacteria 1UA69@1239,3F8RR@33958,4IKH6@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain GOKNOHPG_00795 1033837.WANG_1480 1.1e-16 91.7 Lactobacillaceae Bacteria 1U6JH@1239,29PGF@1,30AEK@2,3F819@33958,4IGBZ@91061 NA|NA|NA GOKNOHPG_00796 326425.lhe_1921 8e-210 736.1 Lactobacillaceae Bacteria 1U547@1239,29NJT@1,309HR@2,3F4IW@33958,4IEVJ@91061 NA|NA|NA GOKNOHPG_00797 326425.lhe_1922 6.1e-280 969.5 Lactobacillaceae clcA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006821,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015672,GO:0015698,GO:0015706,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0031404,GO:0034220,GO:0042802,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 ko:K03281,ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4,2.A.49 iAF1260.b0155,iB21_1397.B21_00153,iBWG_1329.BWG_0148,iE2348C_1286.E2348C_0162,iEC042_1314.EC042_0155,iEC55989_1330.EC55989_0149,iECBD_1354.ECBD_3463,iECDH10B_1368.ECDH10B_0135,iECDH1ME8569_1439.ECDH1ME8569_0149,iECD_1391.ECD_00154,iECIAI1_1343.ECIAI1_0153,iECO103_1326.ECO103_0155,iECSE_1348.ECSE_0156,iECUMN_1333.ECUMN_0152,iECW_1372.ECW_m0152,iEKO11_1354.EKO11_3761,iETEC_1333.ETEC_0151,iEcDH1_1363.EcDH1_3447,iEcE24377_1341.EcE24377A_0160,iEcolC_1368.EcolC_3504,iJO1366.b0155,iSSON_1240.SSON_0167,iUMNK88_1353.UMNK88_159,iWFL_1372.ECW_m0152,iY75_1357.Y75_RS00790,iZ_1308.Z0166 Bacteria 1TPX0@1239,3F3MU@33958,4HD2H@91061,COG0038@1,COG0038@2,COG0569@1,COG0569@2 NA|NA|NA P chloride GOKNOHPG_00798 326425.lhe_1923 1.6e-268 931.4 Lactobacillaceae gnd 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4I@1239,3F3S8@33958,4H9NC@91061,COG0362@1,COG0362@2 NA|NA|NA H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH GOKNOHPG_00799 326425.lhe_1924 0.0 1235.3 Lactobacillaceae gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 ko:K03495 R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 Bacteria 1TQ4B@1239,3F454@33958,4HA6S@91061,COG0445@1,COG0445@2 NA|NA|NA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 GOKNOHPG_00800 405566.lhv_2104 2.1e-252 877.9 Lactobacillaceae mnmE GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K03650 R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 Bacteria 1TPJF@1239,3F3WA@33958,4HA06@91061,COG0486@1,COG0486@2 NA|NA|NA S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 GOKNOHPG_00801 405566.lhv_2105 2.1e-141 508.4 Lactobacillaceae yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 1TQ0J@1239,3F3SD@33958,4HB3J@91061,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins GOKNOHPG_00802 326425.lhe_1927 6e-61 240.0 Lactobacillaceae rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536,ko:K08998 ko00000,ko01000,ko03016 Bacteria 1VA78@1239,3F6GS@33958,4HKG6@91061,COG0594@1,COG0594@2 NA|NA|NA J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme GOKNOHPG_00803 1033837.WANG_1471 1.1e-15 88.2 Lactobacillaceae rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02914 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VK90@1239,3F81W@33958,4HR2Z@91061,COG0230@1,COG0230@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL34 family GOKNOHPG_00804 326425.lhe_0001 5.3e-257 893.3 Lactobacillaceae dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 1TPV7@1239,3F3YA@33958,4H9MW@91061,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids GOKNOHPG_00805 405566.lhv_0002 3.9e-196 690.6 Lactobacillaceae dnaN 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TQ7J@1239,3F3ZQ@33958,4H9TF@91061,COG0592@1,COG0592@2 NA|NA|NA L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria GOKNOHPG_00806 405566.lhv_0003 9.4e-33 145.6 Lactobacillaceae yaaA GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K14761 ko00000,ko03009 Bacteria 1VEJ2@1239,3F803@33958,4HNMC@91061,COG2501@1,COG2501@2 NA|NA|NA S S4 domain protein YaaA GOKNOHPG_00807 1423748.BALB01000029_gene1863 1.7e-207 728.4 Lactobacillaceae recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1TP9U@1239,3F3Q1@33958,4HA0W@91061,COG1195@1,COG1195@2 NA|NA|NA L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP GOKNOHPG_00808 405566.lhv_0005 0.0 1291.2 Lactobacillaceae gyrB GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02470,ko:K02622 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TQ0R@1239,3F48M@33958,4H9Y6@91061,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner GOKNOHPG_00809 405566.lhv_0006 0.0 1575.1 Lactobacillaceae gyrA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TP2Z@1239,3F3YM@33958,4HAHY@91061,COG0188@1,COG0188@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner GOKNOHPG_00810 405566.lhv_0007 4.2e-49 200.3 Lactobacillaceae rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 ko:K02990 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VA18@1239,3FCDH@33958,4HP6B@91061,COG0360@1,COG0360@2 NA|NA|NA J Binds together with S18 to 16S ribosomal RNA GOKNOHPG_00811 326425.lhe_0008 5.8e-78 297.0 Lactobacillaceae ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 1V3WT@1239,3F66N@33958,4HH8I@91061,COG0629@1,COG0629@2 NA|NA|NA L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism GOKNOHPG_00812 1423748.BALB01000029_gene1871 2.8e-35 154.1 Lactobacillaceae rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963,ko:K03111,ko:K15125 ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133 M00178 br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400 Bacteria 1V9XS@1239,3F7CY@33958,4HKCC@91061,COG0238@1,COG0238@2 NA|NA|NA J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit GOKNOHPG_00813 97137.C821_01143 2.5e-15 89.4 Lactobacillaceae Bacteria 1U5EX@1239,2DKJ7@1,309P1@2,3F5TG@33958,4IF6H@91061 NA|NA|NA GOKNOHPG_00814 405566.lhv_1058 4.8e-288 996.5 Lactobacillaceae Bacteria 1TQQ9@1239,3F4M8@33958,4H9KK@91061,COG3666@1,COG3666@2 NA|NA|NA L Transposase GOKNOHPG_00815 1033837.WANG_p1032 2e-39 167.9 Lactobacillaceae ko:K07172 ko00000,ko02048 Bacteria 1U7Y1@1239,2DEZ7@1,2ZPUZ@2,3FAB6@33958,4IHVE@91061 NA|NA|NA S SpoVT / AbrB like domain GOKNOHPG_00816 1033837.WANG_p1033 4.7e-52 210.3 Lactobacillaceae pemK GO:0001558,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009894,GO:0009987,GO:0010468,GO:0010608,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019219,GO:0019222,GO:0030308,GO:0031323,GO:0031329,GO:0034641,GO:0040008,GO:0043170,GO:0043487,GO:0043488,GO:0044237,GO:0044238,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1903311 ko:K07171,ko:K18841 ko00000,ko01000,ko02048 Bacteria 1VBXM@1239,3F6S1@33958,4HM83@91061,COG2337@1,COG2337@2 NA|NA|NA T PemK-like, MazF-like toxin of type II toxin-antitoxin system GOKNOHPG_00817 324831.LGAS_0222 5.2e-11 73.9 Lactobacillaceae dexB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.10,3.2.1.70 ko:K01182,ko:K01215 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13 Bacteria 1TP53@1239,3F41I@33958,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain protein GOKNOHPG_00818 1033837.WANG_1268 1.2e-88 332.4 Lactobacillaceae malE ko:K15770 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 Bacteria 1TPU9@1239,3F50T@33958,4HAK6@91061,COG2182@1,COG2182@2 NA|NA|NA G Bacterial extracellular solute-binding protein GOKNOHPG_00819 1033837.WANG_1268 3.6e-97 360.9 Lactobacillaceae malE ko:K15770 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 Bacteria 1TPU9@1239,3F50T@33958,4HAK6@91061,COG2182@1,COG2182@2 NA|NA|NA G Bacterial extracellular solute-binding protein GOKNOHPG_00820 326425.lhe_1109 1.7e-251 874.8 Lactobacillaceae gor 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1TS0Z@1239,3F3K2@33958,4HBYB@91061,COG1249@1,COG1249@2 NA|NA|NA C Glutathione reductase GOKNOHPG_00821 405566.lhv_1218 7.5e-58 229.6 Lactobacillaceae Bacteria 1V6Z8@1239,3F6WQ@33958,4HMP7@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) family GOKNOHPG_00822 525365.HMPREF0548_1225 1.8e-69 269.2 Lactobacillaceae Bacteria 1VSYU@1239,3F4J2@33958,4HU15@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha beta hydrolase GOKNOHPG_00823 1033837.WANG_1262 1.3e-70 272.3 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TPW7@1239,3F5IC@33958,4HEFQ@91061,COG1073@1,COG1073@2 NA|NA|NA S Hydrolases of the alpha beta superfamily GOKNOHPG_00824 575594.ACOH01000002_gene1160 5.2e-29 133.3 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TPW7@1239,3F5IC@33958,4HEFQ@91061,COG1073@1,COG1073@2 NA|NA|NA S Hydrolases of the alpha beta superfamily GOKNOHPG_00825 1423814.HMPREF0549_0425 9.5e-59 232.6 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TPW7@1239,3F5IC@33958,4HEFQ@91061,COG1073@1,COG1073@2 NA|NA|NA S Hydrolases of the alpha beta superfamily GOKNOHPG_00826 326425.lhe_1112 6.4e-142 510.0 Lactobacillaceae nfrA 1.5.1.38,1.5.1.39 ko:K19285,ko:K19286 ko00740,ko01100,map00740,map01100 R05705,R05706 RC00126 ko00000,ko00001,ko01000 Bacteria 1UB8S@1239,3F4IY@33958,4HEGP@91061,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase GOKNOHPG_00827 326425.lhe_1113 5.7e-29 133.3 Bacteria 1.1.1.3 ko:K00003,ko:K07166 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria COG3830@1,COG3830@2 NA|NA|NA T phosphoserine phosphatase activity GOKNOHPG_00828 525365.HMPREF0548_1170 1.3e-22 111.7 Lactobacillaceae XK27_08635 ko:K09157 ko00000 Bacteria 1TQG8@1239,3F4H2@33958,4HBTU@91061,COG2848@1,COG2848@2 NA|NA|NA S UPF0210 protein GOKNOHPG_00829 405566.lhv_1224 1e-30 139.4 Lactobacillaceae ko:K09705,ko:K12410 ko00000,ko01000 Bacteria 1V192@1239,3F5GG@33958,4IJ3S@91061,COG0846@1,COG0846@2 NA|NA|NA K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form GOKNOHPG_00830 525365.HMPREF0548_1143 1.7e-19 101.7 Lactobacillaceae Bacteria 1V192@1239,3F5GG@33958,4IJ3S@91061,COG0846@1,COG0846@2 NA|NA|NA K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form GOKNOHPG_00831 525365.HMPREF0548_1143 7.7e-70 270.0 Lactobacillaceae Bacteria 1V192@1239,3F5GG@33958,4IJ3S@91061,COG0846@1,COG0846@2 NA|NA|NA K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form GOKNOHPG_00832 326425.lhe_1116 1.9e-71 275.0 Lactobacillaceae Bacteria 1TQB7@1239,3F4Q7@33958,4HAQT@91061,COG0846@1,COG0846@2 NA|NA|NA K COG COG0846 NAD-dependent protein deacetylases, SIR2 family GOKNOHPG_00833 405566.lhv_1226 1.5e-39 168.3 Lactobacillaceae ko:K12410 ko00000,ko01000 Bacteria 1TQB7@1239,3F4Q7@33958,4HAQT@91061,COG0846@1,COG0846@2 NA|NA|NA K COG COG0846 NAD-dependent protein deacetylases, SIR2 family GOKNOHPG_00834 326425.lhe_1116 5.5e-14 82.4 Lactobacillaceae Bacteria 1TQB7@1239,3F4Q7@33958,4HAQT@91061,COG0846@1,COG0846@2 NA|NA|NA K COG COG0846 NAD-dependent protein deacetylases, SIR2 family GOKNOHPG_00835 326425.lhe_1117 2.6e-94 351.3 Lactobacillaceae Bacteria 1V5SA@1239,3FBU8@33958,4ISZX@91061,COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase GOKNOHPG_00836 326425.lhe_1118 5.8e-85 320.1 Lactobacillaceae dps ko:K04047 ko00000,ko03036 Bacteria 1VCVJ@1239,3F5WI@33958,4HMBD@91061,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family GOKNOHPG_00837 525365.HMPREF0548_1229 5.2e-33 147.1 Lactobacillaceae Bacteria 1U67D@1239,29P6U@1,30A4Y@2,3F78T@33958,4IFXW@91061 NA|NA|NA GOKNOHPG_00838 1423748.BALB01000017_gene1504 3.9e-31 140.6 Lactobacillaceae Bacteria 1U6QB@1239,29PK4@1,30AI9@2,3F8AM@33958,4IGHF@91061 NA|NA|NA GOKNOHPG_00839 1423748.BALB01000017_gene1505 7.1e-18 95.5 Lactobacillaceae snf 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 1TPFZ@1239,3F52K@33958,4HAIF@91061,COG0553@1,COG0553@2 NA|NA|NA KL domain protein GOKNOHPG_00840 1423748.BALB01000017_gene1505 1.5e-42 178.7 Lactobacillaceae snf 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 1TPFZ@1239,3F52K@33958,4HAIF@91061,COG0553@1,COG0553@2 NA|NA|NA KL domain protein GOKNOHPG_00841 1423748.BALB01000017_gene1505 6.6e-40 169.9 Lactobacillaceae snf 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 1TPFZ@1239,3F52K@33958,4HAIF@91061,COG0553@1,COG0553@2 NA|NA|NA KL domain protein GOKNOHPG_00842 1423748.BALB01000017_gene1505 1.7e-179 635.6 Lactobacillaceae snf 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 1TPFZ@1239,3F52K@33958,4HAIF@91061,COG0553@1,COG0553@2 NA|NA|NA KL domain protein GOKNOHPG_00843 405566.lhv_1231 6.7e-105 386.7 Lactobacillaceae plsY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15,3.5.1.104 ko:K08591,ko:K22278 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1VA3J@1239,3F543@33958,4HC55@91061,COG0344@1,COG0344@2 NA|NA|NA I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP GOKNOHPG_00844 405566.lhv_1232 0.0 1195.3 Lactobacillaceae parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470,ko:K02622 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TQCF@1239,3F430@33958,4H9UC@91061,COG0187@1,COG0187@2 NA|NA|NA L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule GOKNOHPG_00845 405566.lhv_1233 0.0 1583.5 Lactobacillaceae parC GO:0005575,GO:0005622,GO:0005623,GO:0009330,GO:0032991,GO:0044424,GO:0044464 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TRE7@1239,3F3MJ@33958,4HAQB@91061,COG0188@1,COG0188@2 NA|NA|NA L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule GOKNOHPG_00846 326425.lhe_1123 3.8e-171 607.4 Lactobacillaceae Bacteria 1UYS5@1239,3F48B@33958,4HF07@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator GOKNOHPG_00847 405566.lhv_1235 3.6e-163 580.9 Lactobacillaceae ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1TPH6@1239,3F3PJ@33958,4H9T8@91061,COG1227@1,COG1227@2 NA|NA|NA C inorganic pyrophosphatase GOKNOHPG_00848 326425.lhe_1125 5.5e-109 400.2 Lactobacillaceae ppiB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03768 ko00000,ko01000,ko03110 Bacteria 1TRHW@1239,3F3TI@33958,4H9V0@91061,COG0652@1,COG0652@2 NA|NA|NA G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides GOKNOHPG_00849 326425.lhe_1126 6.8e-54 216.5 Lactobacillaceae Bacteria 1UUUD@1239,3F8QF@33958,4I3X4@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix domain GOKNOHPG_00850 326425.lhe_0348 3.3e-180 637.5 Lactobacillaceae apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 1TR9C@1239,3F3QR@33958,4HHVC@91061,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein GOKNOHPG_00851 405566.lhv_1870 3.1e-147 527.7 Lactobacillaceae 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1VA24@1239,3F4H4@33958,4IQXZ@91061,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family GOKNOHPG_00852 326425.lhe_0346 5e-96 357.1 Lactobacillaceae azr 1.5.1.36 ko:K22393,ko:K22394 ko00740,ko01100,map00740,map01100 R05705,R09748,R09750 RC00126 ko00000,ko00001,ko01000 Bacteria 1TT2S@1239,3F544@33958,4HBQI@91061,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase GOKNOHPG_00853 326425.lhe_0345 7.9e-94 349.7 Lactobacillaceae nqr 1.5.1.36 ko:K22393,ko:K22394 ko00740,ko01100,map00740,map01100 R05705,R09748,R09750 RC00126 ko00000,ko00001,ko01000 Bacteria 1VI8F@1239,3FCC2@33958,4HPT0@91061,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase GOKNOHPG_00854 405566.lhv_1873 5e-108 397.1 Lactobacillaceae Bacteria 1U9UE@1239,3F403@33958,4HM7U@91061,COG1309@1,COG1309@2 NA|NA|NA K WHG domain GOKNOHPG_00855 326425.lhe_0342 1.1e-36 158.7 Lactobacillaceae Bacteria 1U6B2@1239,2A5EV@1,30U4Q@2,3F7HR@33958,4IG2J@91061 NA|NA|NA GOKNOHPG_00856 405566.lhv_1877 1.7e-273 948.0 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase GOKNOHPG_00857 326425.lhe_0340 2.8e-117 427.9 Lactobacillaceae devA 3.6.3.25 ko:K02003,ko:K06020,ko:K09810 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 Bacteria 1TQP5@1239,3F4RP@33958,4HBXK@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein GOKNOHPG_00858 405566.lhv_1879 5.8e-165 587.0 Lactobacillaceae hrtB ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TWFZ@1239,3F3K5@33958,4H9RQ@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease GOKNOHPG_00859 326425.lhe_0338 4.5e-94 350.5 Lactobacillaceae ygfC Bacteria 1V4D3@1239,3F6ZM@33958,4HJ8Z@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family GOKNOHPG_00860 405566.lhv_1881 3.9e-110 404.1 Lactobacillaceae Bacteria 1V6ES@1239,3F5SD@33958,4HGZI@91061,COG0406@1,COG0406@2 NA|NA|NA G phosphoglycerate mutase GOKNOHPG_00861 326425.lhe_0336 1.9e-141 508.4 Lactobacillaceae aroD ko:K06889 ko00000 Bacteria 1V43W@1239,3F4SI@33958,4HNBU@91061,COG1073@1,COG1073@2 NA|NA|NA S Alpha/beta hydrolase family GOKNOHPG_00862 405566.lhv_1883 1.3e-142 512.3 Lactobacillaceae ko:K09861 ko00000 Bacteria 1TR33@1239,3F4KR@33958,4HFN2@91061,COG3022@1,COG3022@2 NA|NA|NA S Belongs to the UPF0246 family GOKNOHPG_00863 326425.lhe_0334 1.1e-118 432.6 Lactobacillaceae Bacteria 1U59M@1239,2CBCD@1,309KB@2,3F5A8@33958,4IF11@91061 NA|NA|NA GOKNOHPG_00864 1423748.BALB01000012_gene1253 1.4e-77 295.4 Lactobacillaceae 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSNU@1239,3F3JH@33958,4H9TY@91061,COG1085@1,COG1085@2 NA|NA|NA C Domain of unknown function (DUF4931) GOKNOHPG_00865 1423748.BALB01000035_gene1982 5e-181 640.6 Lactobacillaceae Bacteria 1TQMA@1239,3F3QW@33958,4HDTN@91061,COG1376@1,COG1376@2 NA|NA|NA S Putative peptidoglycan binding domain GOKNOHPG_00866 1423748.BALB01000035_gene1981 1.5e-23 114.8 Lactobacillaceae Bacteria 1U6RB@1239,29PKP@1,30AIV@2,3F8CU@33958,4IGIQ@91061 NA|NA|NA GOKNOHPG_00867 1423748.BALB01000035_gene1980 5.5e-188 663.7 Lactobacillaceae dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03305 ko00000 2.A.17 Bacteria 1TP81@1239,3F4WU@33958,4HAF2@91061,COG3104@1,COG3104@2 NA|NA|NA U amino acid peptide transporter GOKNOHPG_00868 1423748.BALB01000035_gene1980 1.3e-32 145.2 Lactobacillaceae dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03305 ko00000 2.A.17 Bacteria 1TP81@1239,3F4WU@33958,4HAF2@91061,COG3104@1,COG3104@2 NA|NA|NA U amino acid peptide transporter GOKNOHPG_00869 405566.lhv_1886 0.0 1666.4 Lactobacillaceae pepN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 1TR43@1239,3F3UH@33958,4HA20@91061,COG0308@1,COG0308@2 NA|NA|NA E aminopeptidase GOKNOHPG_00871 326425.lhe_0329 4e-57 227.3 Lactobacillaceae lysM Bacteria 1U5V5@1239,3F6J1@33958,4IFIT@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain GOKNOHPG_00872 405566.lhv_1888 2.1e-169 601.7 Lactobacillaceae Bacteria 1U59F@1239,29NN9@1,309K7@2,3F59C@33958,4IF0Q@91061 NA|NA|NA GOKNOHPG_00873 1423748.BALB01000035_gene1973 6.7e-213 746.5 Lactobacillaceae mdtG GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085 ko:K08161 ko00000,ko02000 2.A.1.2.20 Bacteria 1TRDJ@1239,3F3T5@33958,4H9Q9@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GOKNOHPG_00874 405566.lhv_0505 1.1e-136 492.7 Bacilli ko:K07496 ko00000 Bacteria 1TRNY@1239,4HBKP@91061,COG0675@1,COG0675@2 NA|NA|NA L Transposase GOKNOHPG_00875 1033837.WANG_1516 9.5e-71 272.7 Lactobacillaceae Bacteria 1VY6M@1239,29NZE@1,309XJ@2,3F9SI@33958,4HXWC@91061 NA|NA|NA L IS1381, transposase OrfA GOKNOHPG_00876 405566.lhv_0153 5.7e-80 303.5 Lactobacillaceae ntd 2.4.2.6 ko:K08728 ko00240,map00240 R02806 RC00063 ko00000,ko00001,ko01000 Bacteria 1VY4Q@1239,3F5CB@33958,4HXB4@91061,COG3613@1,COG3613@2 NA|NA|NA F Nucleoside GOKNOHPG_00877 405566.lhv_0154 1.4e-89 335.5 Lactobacillaceae 2.7.1.200,2.7.1.202,2.7.1.204 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K20112 ko00051,ko00052,ko01100,ko01120,ko02060,map00051,map00052,map01100,map01120,map02060 M00273,M00279,M00807 R03232,R05570,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.5,4.A.5.1 Bacteria 1V8H9@1239,3F4A7@33958,4HK36@91061,COG1762@1,COG1762@2 NA|NA|NA G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 GOKNOHPG_00878 405566.lhv_0151 3.1e-98 364.4 Lactobacillaceae isp2 Bacteria 1TQ93@1239,3F4RD@33958,4HDNZ@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein GOKNOHPG_00879 1033837.WANG_0698 5.4e-33 146.4 Lactobacillaceae Bacteria 1TQ93@1239,3F4RD@33958,4HDNZ@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein GOKNOHPG_00880 1033837.WANG_0698 1.4e-33 148.3 Lactobacillaceae Bacteria 1TQ93@1239,3F4RD@33958,4HDNZ@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein GOKNOHPG_00881 326425.lhe_1843 1.4e-66 258.8 Lactobacillaceae Bacteria 1U64K@1239,29P4Y@1,30A35@2,3F712@33958,4IFU4@91061 NA|NA|NA S Domain of unknown function (DUF1934) GOKNOHPG_00882 326425.lhe_1842 3.9e-48 198.0 Lactobacillaceae rpoE GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Bacteria 1V6WX@1239,3F55D@33958,4HIUK@91061,COG3343@1,COG3343@2 NA|NA|NA K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling GOKNOHPG_00883 326425.lhe_1841 2.2e-311 1074.3 Lactobacillaceae pyrG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS01075,iNJ661.Rv1699 Bacteria 1TP34@1239,3F42X@33958,4H9X6@91061,COG0504@1,COG0504@2 NA|NA|NA F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates GOKNOHPG_00884 405566.lhv_0248 2.8e-246 857.4 Lactobacillaceae murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 iYO844.BSU37100 Bacteria 1TPAU@1239,3F3P8@33958,4H9KI@91061,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine GOKNOHPG_00885 1423748.BALB01000008_gene975 3.7e-33 147.1 Lactobacillaceae GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0044237,GO:0050308,GO:0050309 Bacteria 1V1N8@1239,3F8H8@33958,4HG58@91061,COG0637@1,COG0637@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase GOKNOHPG_00886 405566.lhv_0249 4.4e-49 200.3 Lactobacillaceae GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0044237,GO:0050308,GO:0050309 Bacteria 1V1N8@1239,3F8H8@33958,4HG58@91061,COG0637@1,COG0637@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase GOKNOHPG_00887 405566.lhv_0250 9.1e-283 978.8 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase GOKNOHPG_00888 326425.lhe_1837 2.6e-157 561.2 Lactobacillaceae msmR Bacteria 1V8G6@1239,3FBER@33958,4HIF6@91061,COG2207@1,COG2207@2 NA|NA|NA K AraC-like ligand binding domain GOKNOHPG_00889 1033837.WANG_1860 6.4e-219 766.5 Lactobacillaceae pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 ko:K02824,ko:K03458,ko:K16169,ko:K16170 ko00000,ko02000 2.A.40,2.A.40.1.1,2.A.40.1.2,2.A.40.3.1,2.A.40.3.2 iSB619.SA_RS02140 Bacteria 1TNZZ@1239,3F3Y7@33958,4HBAM@91061,COG2233@1,COG2233@2 NA|NA|NA F xanthine permease GOKNOHPG_00890 326425.lhe_1835 9.6e-98 362.8 Lactobacillaceae xpt GO:0003674,GO:0003824,GO:0006139,GO:0006166,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046128,GO:0046129,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816,ko:K09685 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko03000,ko04147 iYO844.BSU22070 Bacteria 1V1DU@1239,3F49S@33958,4HFNW@91061,COG0503@1,COG0503@2 NA|NA|NA F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis GOKNOHPG_00891 326425.lhe_1834 3.6e-54 217.2 Lactobacillaceae Bacteria 1V36C@1239,3F65G@33958,4IT3D@91061,COG1476@1,COG1476@2 NA|NA|NA K DNA-binding helix-turn-helix protein GOKNOHPG_00892 1423748.BALB01000008_gene981 1.1e-10 73.2 Lactobacillaceae Bacteria 1UHWD@1239,3FBYR@33958,4IU4I@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix GOKNOHPG_00893 326425.lhe_1831 4.9e-17 92.8 Lactobacillaceae Bacteria 1VETP@1239,3F4HG@33958,4HCJ3@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix GOKNOHPG_00894 326425.lhe_1830 1.8e-300 1037.7 Lactobacillaceae guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 ko:K01951,ko:K03790 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002,ko03009 iLJ478.TM1820 Bacteria 1TPG8@1239,3F3NV@33958,4HA7Q@91061,COG0519@1,COG0519@2 NA|NA|NA F Catalyzes the synthesis of GMP from XMP GOKNOHPG_00895 713605.ADHG01000001_gene220 1.8e-82 312.0 Lactobacillaceae yeeA Bacteria 1TRZH@1239,3F4XU@33958,4HE9W@91061,COG1002@1,COG1002@2 NA|NA|NA V Type II restriction enzyme, methylase subunits GOKNOHPG_00896 1033837.WANG_1867 2.6e-121 441.4 Lactobacillaceae yeeB Bacteria 1TQUR@1239,3F4UP@33958,4HDB4@91061,COG1061@1,COG1061@2 NA|NA|NA L DEAD-like helicases superfamily GOKNOHPG_00897 1033837.WANG_1868 6e-75 287.0 Lactobacillaceae pstS ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1V2DG@1239,3F623@33958,4HFZU@91061,COG0226@1,COG0226@2 NA|NA|NA P T5orf172 GOKNOHPG_00898 1033837.WANG_1868 1.2e-24 118.6 Lactobacillaceae pstS ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1V2DG@1239,3F623@33958,4HFZU@91061,COG0226@1,COG0226@2 NA|NA|NA P T5orf172 GOKNOHPG_00899 713605.ADHG01000001_gene217 1.2e-80 305.8 Lactobacillaceae pstS ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1V2DG@1239,3F623@33958,4HFZU@91061,COG0226@1,COG0226@2 NA|NA|NA P T5orf172 GOKNOHPG_00900 525365.HMPREF0548_0003 3.6e-53 214.2 Lactobacillaceae Bacteria 1TRSF@1239,3F3YG@33958,4HADR@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family GOKNOHPG_00901 1033837.WANG_p1034 9.2e-39 165.6 Lactobacillaceae Bacteria 1TRSF@1239,3F3YG@33958,4HADR@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family GOKNOHPG_00902 326425.lhe_1825 3.5e-230 803.9 Lactobacillaceae glyA 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQVM@1239,3F4C1@33958,4HA5K@91061,COG0112@1,COG0112@2 NA|NA|NA E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism GOKNOHPG_00903 405566.lhv_0384 2.2e-185 654.8 Lactobacillaceae isp2 Bacteria 1TQ93@1239,3F4RD@33958,4HDNZ@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein GOKNOHPG_00904 1033837.WANG_p1012 1.2e-13 81.3 Lactobacillaceae Bacteria 1TQ93@1239,3F4RD@33958,4HDNZ@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein GOKNOHPG_00905 1423748.BALB01000010_gene1069 4e-26 123.6 Lactobacillaceae Bacteria 1TQQ9@1239,3F4M8@33958,4H9KK@91061,COG3666@1,COG3666@2 NA|NA|NA L Transposase GOKNOHPG_00906 272621.LBA0077 7.3e-68 263.8 Lactobacillaceae Bacteria 1TQQ9@1239,3F4M8@33958,4H9KK@91061,COG3666@1,COG3666@2 NA|NA|NA L Transposase GOKNOHPG_00907 405566.lhv_0273 1.3e-154 552.4 Lactobacillaceae Bacteria 1U5TY@1239,2DI1S@1,301QZ@2,3F6I2@33958,4IFHX@91061 NA|NA|NA GOKNOHPG_00908 326425.lhe_1823 1.2e-91 342.4 Lactobacillaceae Bacteria 1U53C@1239,29NJD@1,309H9@2,3F4BP@33958,4IEUN@91061 NA|NA|NA S Bacteriocin helveticin-J GOKNOHPG_00909 326425.lhe_1823 2.4e-78 298.1 Lactobacillaceae Bacteria 1U53C@1239,29NJD@1,309H9@2,3F4BP@33958,4IEUN@91061 NA|NA|NA S Bacteriocin helveticin-J GOKNOHPG_00910 405566.lhv_0277 1.2e-175 622.5 Lactobacillaceae Bacteria 1U5FB@1239,2DKJ8@1,309P7@2,3F5UP@33958,4IF6X@91061 NA|NA|NA S SLAP domain GOKNOHPG_00911 405566.lhv_0742 9.8e-186 656.0 Lactobacillaceae cggR ko:K05311 ko00000,ko03000 Bacteria 1TP62@1239,3F53Y@33958,4HAE6@91061,COG2390@1,COG2390@2 NA|NA|NA K Putative sugar-binding domain GOKNOHPG_00912 1423748.BALB01000001_gene161 6.5e-190 669.8 Lactobacillaceae gap GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009986,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0022610,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044464,GO:0044650,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:0140030,GO:0140032,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iJR904.b1416,iJR904.b1417 Bacteria 1TNYU@1239,3F3JS@33958,4H9NS@91061,COG0057@1,COG0057@2 NA|NA|NA G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family GOKNOHPG_00913 326425.lhe_0709 4.6e-227 793.5 Lactobacillaceae pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iSB619.SA_RS04145 Bacteria 1TP3H@1239,3F3SC@33958,4H9R3@91061,COG0126@1,COG0126@2 NA|NA|NA F Belongs to the phosphoglycerate kinase family GOKNOHPG_00914 1423748.BALB01000001_gene159 1.3e-142 512.3 Lactobacillaceae tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS19265 Bacteria 1TP2F@1239,3F494@33958,4HAPT@91061,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) GOKNOHPG_00915 1423748.BALB01000001_gene156 1.5e-94 352.1 Lactobacillaceae Bacteria 1U5NS@1239,29NVF@1,309TI@2,3F68I@33958,4IFDC@91061 NA|NA|NA GOKNOHPG_00916 326425.lhe_0712 9.7e-158 562.8 Lactobacillaceae ycsE Bacteria 1V5FB@1239,3F58Y@33958,4HGY8@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase GOKNOHPG_00917 326425.lhe_0713 9.7e-137 492.7 Lactobacillaceae ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPSN@1239,3F3W0@33958,4HBTR@91061,COG0692@1,COG0692@2 NA|NA|NA L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine GOKNOHPG_00918 326425.lhe_0714 1.3e-179 635.6 Lactobacillaceae pta 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028,ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 iSB619.SA_RS03155 Bacteria 1TPQ0@1239,3F3MW@33958,4H9VH@91061,COG0280@1,COG0280@2 NA|NA|NA C phosphate acetyltransferase GOKNOHPG_00919 405566.lhv_0750 1.9e-89 335.1 Lactobacillaceae ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.1.221,5.1.1.1 ko:K01775,ko:K06925,ko:K07102 ko00473,ko00520,ko01100,ko01502,map00473,map00520,map01100,map01502 R00401,R08968,R11024 RC00002,RC00078,RC00285 ko00000,ko00001,ko01000,ko01011,ko03016 Bacteria 1V6CV@1239,3F3MR@33958,4HIIF@91061,COG0802@1,COG0802@2 NA|NA|NA O Hydrolase, P-loop family GOKNOHPG_00920 1423748.BALB01000001_gene151 1.4e-98 365.5 Lactobacillaceae dnaQ 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1V57H@1239,3F42Z@33958,4HI1V@91061,COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III GOKNOHPG_00921 405566.lhv_0752 7e-164 583.2 Lactobacillaceae murB 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 Bacteria 1TP3W@1239,3F40T@33958,4HAD8@91061,COG0812@1,COG0812@2 NA|NA|NA M Cell wall formation GOKNOHPG_00922 1423748.BALB01000001_gene149 1.4e-203 715.3 Lactobacillaceae potA 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 iSB619.SA_RS05380 Bacteria 1TP2M@1239,3F40H@33958,4H9MS@91061,COG3842@1,COG3842@2 NA|NA|NA P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system GOKNOHPG_00923 326425.lhe_0719 1.3e-129 469.2 Lactobacillaceae potB ko:K11071 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 Bacteria 1TQ7Z@1239,3F4CM@33958,4HAYS@91061,COG1176@1,COG1176@2 NA|NA|NA P ABC transporter permease GOKNOHPG_00924 326425.lhe_0720 6.5e-124 450.3 Lactobacillaceae potC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008519,GO:0015075,GO:0015101,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015595,GO:0015606,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072488,GO:0098533,GO:0098655,GO:0098796,GO:0098797,GO:1902047,GO:1902494,GO:1902495,GO:1903711,GO:1904949,GO:1990351 ko:K11070 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 iSBO_1134.SBO_1939 Bacteria 1V0VD@1239,3F3ZN@33958,4H9ZC@91061,COG1177@1,COG1177@2 NA|NA|NA P ABC transporter permease GOKNOHPG_00925 405566.lhv_0756 3.7e-204 717.2 Lactobacillaceae potD ko:K11069 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 iSB619.SA_RS05395 Bacteria 1TPY1@1239,3F3W1@33958,4HAET@91061,COG0687@1,COG0687@2 NA|NA|NA P ABC transporter GOKNOHPG_00926 326425.lhe_0722 1.2e-149 535.8 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 ko00000,ko01000 Bacteria 1TPRW@1239,3F4N3@33958,4H9XZ@91061,COG1624@1,COG1624@2 NA|NA|NA S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria GOKNOHPG_00927 405566.lhv_0758 8.3e-171 606.3 Lactobacillaceae ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 Bacteria 1TSIV@1239,3F41C@33958,4HD8Y@91061,COG4856@1,COG4856@2 NA|NA|NA S YbbR-like protein GOKNOHPG_00928 326425.lhe_0724 4.1e-256 890.2 Lactobacillaceae glmM GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 R02060 RC00408 ko00000,ko00001,ko01000 iSB619.SA_RS11275,iSBO_1134.SBO_3206 Bacteria 1TP1X@1239,3F3W5@33958,4HB16@91061,COG1109@1,COG1109@2 NA|NA|NA G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate GOKNOHPG_00929 326425.lhe_0725 9.8e-22 108.6 Lactobacillaceae Bacteria 1TR16@1239,3F55S@33958,4HCZ6@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase GOKNOHPG_00930 405566.lhv_0760 3e-104 384.4 Lactobacillaceae Bacteria 1TR16@1239,3F55S@33958,4HCZ6@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase GOKNOHPG_00931 326425.lhe_0726 1.9e-88 332.0 Lactobacillaceae Bacteria 1U3W2@1239,3FC85@33958,4HM9S@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase GOKNOHPG_00932 405566.lhv_0761 6.2e-24 115.9 Lactobacillaceae Bacteria 1U3W2@1239,3FC85@33958,4HM9S@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase GOKNOHPG_00933 405566.lhv_0762 4.9e-112 410.6 Lactobacillaceae Bacteria 1U56K@1239,29NKW@1,309IV@2,3F4Y0@33958,4IEXT@91061 NA|NA|NA GOKNOHPG_00934 326425.lhe_0728 4.4e-85 320.5 Lactobacillaceae ptpA 3.1.3.48 ko:K01104,ko:K20945 ko05111,map05111 ko00000,ko00001,ko01000 Bacteria 1V6SG@1239,3F74A@33958,4HIZN@91061,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family GOKNOHPG_00935 405566.lhv_0764 4.3e-214 750.4 Lactobacillaceae glxK 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 R08572 RC00002,RC00428 ko00000,ko00001,ko01000 Bacteria 1TPSI@1239,3F3V2@33958,4HA91@91061,COG1929@1,COG1929@2 NA|NA|NA G Belongs to the glycerate kinase type-1 family GOKNOHPG_00936 748671.LCRIS_00729 6.8e-28 129.8 Lactobacillaceae licT ko:K02538,ko:K03488 ko00000,ko03000 Bacteria 1TT5A@1239,3F4SJ@33958,4HC5Y@91061,COG3711@1,COG3711@2 NA|NA|NA K CAT RNA binding domain GOKNOHPG_00937 1423748.BALB01000001_gene134 8.1e-142 509.6 Lactobacillaceae 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family GOKNOHPG_00938 1423748.BALB01000001_gene134 5.4e-55 219.9 Lactobacillaceae 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family GOKNOHPG_00939 1423748.BALB01000001_gene134 3.7e-47 193.7 Lactobacillaceae 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family GOKNOHPG_00940 405566.lhv_0771 1e-184 652.5 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TQYU@1239,3F43H@33958,4HC4H@91061,COG1073@1,COG1073@2 NA|NA|NA D Alpha beta GOKNOHPG_00941 1423748.BALB01000019_gene1575 1.4e-09 67.8 Lactobacillaceae Bacteria 1TR5A@1239,3F7II@33958,4IT3F@91061,COG3976@1,COG3976@2 NA|NA|NA C FMN_bind GOKNOHPG_00942 405566.lhv_1690 1.1e-144 519.2 Lactobacillaceae Bacteria 1UZVA@1239,3F4KP@33958,4HH09@91061,COG3039@1,COG3039@2 NA|NA|NA L An automated process has identified a potential problem with this gene model GOKNOHPG_00943 405566.lhv_0914 8.1e-296 1022.3 Lactobacillaceae Bacteria 1UHVZ@1239,3F5G1@33958,4ISGG@91061,COG2267@1,COG2267@2 NA|NA|NA I Protein of unknown function (DUF2974) GOKNOHPG_00944 1423748.BALB01000019_gene1577 6.3e-111 406.8 Lactobacillaceae 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1U7WX@1239,3F4BS@33958,4HHQT@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain GOKNOHPG_00945 405566.lhv_0912 1.9e-203 714.9 Lactobacillaceae pbpX1 Bacteria 1V4BS@1239,3F3QN@33958,4HJRT@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase GOKNOHPG_00946 405566.lhv_0911 3.3e-197 694.1 Lactobacillaceae asd 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC6@1239,3F4S9@33958,4HA9H@91061,COG0136@1,COG0136@2 NA|NA|NA E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate GOKNOHPG_00947 326425.lhe_0874 2.2e-210 738.0 Lactobacillaceae aspC 2.6.1.1 ko:K00812,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00525 R00355,R00694,R00734,R00896,R02433,R02619,R04467,R05052 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase GOKNOHPG_00948 326425.lhe_0873 7.8e-143 513.1 Lactobacillaceae dapB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 iJN678.dapB,iNJ661.Rv2773c,iYO844.BSU22490 Bacteria 1TR9D@1239,3F3MA@33958,4HA5X@91061,COG0289@1,COG0289@2 NA|NA|NA E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate GOKNOHPG_00949 326425.lhe_0872 2.3e-173 614.8 Lactobacillaceae dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCK@1239,3F4UH@33958,4H9K9@91061,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) GOKNOHPG_00950 405566.lhv_0907 2.9e-218 764.2 Lactobacillaceae hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823,ko:K21613 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPD7@1239,3F419@33958,4H9SG@91061,COG1473@1,COG1473@2 NA|NA|NA E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate GOKNOHPG_00951 326425.lhe_0870 3.6e-78 298.1 Lactobacillaceae dapD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 iSbBS512_1146.SbBS512_E0158,iYO844.BSU14180 Bacteria 1TQUJ@1239,3F3U0@33958,4H9KY@91061,COG2171@1,COG2171@2 NA|NA|NA E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate GOKNOHPG_00952 405566.lhv_0905 4.8e-246 856.7 Lactobacillaceae lysA 4.1.1.19,4.1.1.20 ko:K01585,ko:K01586 ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map01100,map01110,map01120,map01130,map01230 M00016,M00133,M00525,M00526,M00527 R00451,R00566 RC00299 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS18870 Bacteria 1TPE9@1239,3F3VJ@33958,4H9XW@91061,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine GOKNOHPG_00953 326425.lhe_0868 8e-260 902.5 Lactobacillaceae lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iYO844.BSU03790 Bacteria 1TPQJ@1239,3F48V@33958,4HAEP@91061,COG0527@1,COG0527@2 NA|NA|NA E Belongs to the aspartokinase family GOKNOHPG_00954 405566.lhv_0902 1e-187 662.5 Lactobacillaceae dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMN@1239,3F4F7@33958,4HBH4@91061,COG0253@1,COG0253@2 NA|NA|NA E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan GOKNOHPG_00955 891391.LAC30SC_04260 2.6e-272 944.1 Lactobacillaceae yjeM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1TRFS@1239,3F4J0@33958,4HA0N@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid GOKNOHPG_00956 405566.lhv_0898 5.4e-104 383.6 Lactobacillaceae engB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03978 ko00000,ko03036 Bacteria 1TSPW@1239,3F44G@33958,4HBXZ@91061,COG0218@1,COG0218@2 NA|NA|NA D Necessary for normal cell division and for the maintenance of normal septation GOKNOHPG_00957 326425.lhe_0864 9.5e-231 805.8 Lactobacillaceae clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 1TQ00@1239,3F41K@33958,4H9U4@91061,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP GOKNOHPG_00958 326425.lhe_0863 5.8e-207 726.9 Lactobacillaceae tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K03545 ko00000 Bacteria 1TQQ8@1239,3F40B@33958,4H9Q8@91061,COG0544@1,COG0544@2 NA|NA|NA D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase GOKNOHPG_00959 1423748.BALB01000001_gene5 3e-223 780.8 Lactobacillaceae tuf GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 ko:K02358,ko:K15771 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 Bacteria 1TPKC@1239,3F3ZP@33958,4HAEH@91061,COG0050@1,COG0050@2 NA|NA|NA J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis GOKNOHPG_00960 405566.lhv_0894 8.3e-151 539.7 Lactobacillaceae Bacteria 1TW9B@1239,2CC00@1,30489@2,3F52A@33958,4I50I@91061 NA|NA|NA GOKNOHPG_00961 405566.lhv_0893 0.0 1092.0 Lactobacillaceae rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TQ9G@1239,3F3U9@33958,4HAAP@91061,COG0595@1,COG0595@2 NA|NA|NA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay GOKNOHPG_00962 1423748.BALB01000001_gene8 1.2e-42 178.7 Lactobacillaceae rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VA5C@1239,3F7DV@33958,4HKE9@91061,COG0184@1,COG0184@2 NA|NA|NA J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome GOKNOHPG_00963 272621.LBA0841 3.3e-34 150.6 Lactobacillaceae rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02968 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEGX@1239,3F7D8@33958,4HNJS@91061,COG0268@1,COG0268@2 NA|NA|NA J Binds directly to 16S ribosomal RNA GOKNOHPG_00964 326425.lhe_0857 5.9e-172 610.1 Lactobacillaceae holA 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TRM0@1239,3F3TP@33958,4HBB4@91061,COG1466@1,COG1466@2 NA|NA|NA L DNA polymerase III delta subunit GOKNOHPG_00965 326425.lhe_0856 0.0 1438.3 Lactobacillaceae comEC ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1TS9U@1239,3F3VT@33958,4H9M4@91061,COG0658@1,COG0658@2,COG2333@1,COG2333@2 NA|NA|NA S Competence protein ComEC GOKNOHPG_00966 405566.lhv_0888 2.6e-81 308.5 Lactobacillaceae comEA ko:K02237 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1VA3W@1239,3F7NP@33958,4HKJ1@91061,COG1555@1,COG1555@2 NA|NA|NA L Competence protein ComEA GOKNOHPG_00967 405566.lhv_0887 6.4e-193 679.9 Lactobacillaceae ylbL ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Bacteria 1TRUF@1239,3F4KY@33958,4HBAY@91061,COG3480@1,COG3480@2 NA|NA|NA T Belongs to the peptidase S16 family GOKNOHPG_00968 405566.lhv_0886 2.7e-85 321.2 Lactobacillaceae coaD GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0015939,GO:0015940,GO:0016043,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046390,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 iPC815.YPO0053,iSDY_1059.SDY_4064 Bacteria 1V3MR@1239,3FCD3@33958,4HH47@91061,COG0669@1,COG0669@2 NA|NA|NA H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate GOKNOHPG_00969 326425.lhe_0852 1.5e-95 355.5 Lactobacillaceae rsmD 2.1.1.171 ko:K08316 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1V3JF@1239,3F505@33958,4HGXT@91061,COG0742@1,COG0742@2 NA|NA|NA L RNA methyltransferase, RsmD family GOKNOHPG_00970 326425.lhe_0851 2.5e-53 214.5 Lactobacillaceae ylbG Bacteria 1VF52@1239,3F70V@33958,4HNTH@91061,COG4471@1,COG4471@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2129) GOKNOHPG_00971 326425.lhe_0850 1.1e-204 719.2 Lactobacillaceae ftsW ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 2.A.103.1 Bacteria 1TPT7@1239,3F4IK@33958,4HAEV@91061,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family GOKNOHPG_00972 1423748.BALB01000001_gene18 0.0 1206.0 Lactobacillaceae typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 ko:K06207 ko00000 Bacteria 1TQ5Y@1239,3F3UK@33958,4HAQ6@91061,COG1217@1,COG1217@2 NA|NA|NA T GTP-binding protein TypA GOKNOHPG_00973 326425.lhe_0848 8.9e-101 372.9 Lactobacillaceae def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 ko:K01450,ko:K01462 ko00270,ko00630,map00270,map00630 R00653 RC00165,RC00323 ko00000,ko00001,ko01000 Bacteria 1V70B@1239,3F3YH@33958,4HH0G@91061,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions GOKNOHPG_00974 1033837.WANG_0819 4.2e-33 146.7 Lactobacillaceae ykzG Bacteria 1VEI7@1239,3F807@33958,4HNSK@91061,COG5503@1,COG5503@2 NA|NA|NA S Belongs to the UPF0356 family GOKNOHPG_00975 1423748.BALB01000001_gene21 0.0 1092.4 Lactobacillaceae rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TQ9G@1239,3F3TT@33958,4HAAP@91061,COG0595@1,COG0595@2 NA|NA|NA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay GOKNOHPG_00976 1423748.BALB01000001_gene22 2.3e-29 134.4 Lactobacillaceae ytlR 2.7.1.91 ko:K04718 ko00600,ko01100,ko04020,ko04071,ko04072,ko04370,ko04371,ko04666,ko05152,map00600,map01100,map04020,map04071,map04072,map04370,map04371,map04666,map05152 M00100 R01926,R02976 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V7DZ@1239,3F5GQ@33958,4HBUD@91061,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain GOKNOHPG_00977 1423748.BALB01000001_gene22 3.6e-73 281.2 Lactobacillaceae ytlR 2.7.1.91 ko:K04718 ko00600,ko01100,ko04020,ko04071,ko04072,ko04370,ko04371,ko04666,ko05152,map00600,map01100,map04020,map04071,map04072,map04370,map04371,map04666,map05152 M00100 R01926,R02976 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V7DZ@1239,3F5GQ@33958,4HBUD@91061,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain GOKNOHPG_00978 405566.lhv_0873 0.0 1516.1 Lactobacillaceae recD2 3.1.11.5 ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPZH@1239,3F44X@33958,4HATQ@91061,COG0507@1,COG0507@2 NA|NA|NA L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity GOKNOHPG_00979 326425.lhe_0843 1.1e-102 379.4 Lactobacillaceae Bacteria 1VFGR@1239,3F4MD@33958,4IBSH@91061,COG0457@1,COG0457@2 NA|NA|NA S Repeat protein GOKNOHPG_00980 405566.lhv_0871 4.7e-125 453.8 Lactobacillaceae pgm6 5.4.2.11,5.4.2.12 ko:K01834,ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1V7EZ@1239,3FBD9@33958,4HJCK@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family GOKNOHPG_00981 405566.lhv_0869 1.5e-219 768.5 Lactobacillaceae mnmA GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 Bacteria 1TPIZ@1239,3F4N5@33958,4HBJ6@91061,COG0482@1,COG0482@2 NA|NA|NA J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 GOKNOHPG_00982 326425.lhe_0840 1.4e-56 225.3 Lactobacillaceae XK27_04120 Bacteria 1VDSF@1239,2DHWG@1,32U9W@2,3F7E3@33958,4HP9N@91061 NA|NA|NA S Putative amino acid metabolism GOKNOHPG_00983 326425.lhe_0839 1e-215 755.7 Lactobacillaceae iscS 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TP21@1239,3F3RF@33958,4HA6H@91061,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class V GOKNOHPG_00984 326425.lhe_0838 7.2e-124 449.9 Lactobacillaceae mtnN 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 Bacteria 1U7WK@1239,3F4HE@33958,4HB8K@91061,COG0775@1,COG0775@2 NA|NA|NA E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively GOKNOHPG_00985 326425.lhe_0837 5.6e-36 156.8 Lactobacillaceae Bacteria 1U6T4@1239,2B5KT@1,31YFV@2,3F8FY@33958,4IGKV@91061 NA|NA|NA GOKNOHPG_00986 326425.lhe_0836 1.3e-102 379.0 Lactobacillaceae nudF 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 iHN637.CLJU_RS05505,iSB619.SA_RS07540,iYO844.BSU23610 Bacteria 1V6F5@1239,3F53J@33958,4HII9@91061,COG0494@1,COG0494@2 NA|NA|NA L ADP-ribose pyrophosphatase GOKNOHPG_00987 1423748.BALB01000001_gene32 2.1e-31 141.0 Lactobacillaceae cspA ko:K03704 ko00000,ko03000 Bacteria 1U6DB@1239,3F7NC@33958,4IG52@91061,COG1278@1,COG1278@2 NA|NA|NA K 'Cold-shock' DNA-binding domain GOKNOHPG_00988 405566.lhv_0863 0.0 1902.5 Lactobacillaceae ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_0027,iPC815.YPO0475 Bacteria 1TPS7@1239,3F3X4@33958,4HAWB@91061,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) GOKNOHPG_00989 326425.lhe_0833 2.3e-97 362.1 Lactobacillaceae gpsB ko:K04074 ko00000,ko03036 Bacteria 1V27M@1239,3F4IN@33958,4HG80@91061,COG3599@1,COG3599@2 NA|NA|NA D DivIVA domain protein GOKNOHPG_00990 405566.lhv_0861 9.7e-149 532.7 Lactobacillaceae ylmH ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 Bacteria 1U5V2@1239,3F48W@33958,4HD3F@91061,COG2302@1,COG2302@2 NA|NA|NA S S4 domain protein GOKNOHPG_00991 326425.lhe_0831 2.2e-45 188.0 Lactobacillaceae yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02221 ko00000,ko02044 Bacteria 1U6JG@1239,3F818@33958,4IGBY@91061,COG0762@1,COG0762@2 NA|NA|NA S YGGT family GOKNOHPG_00992 1423748.BALB01000001_gene37 2e-71 275.0 Lactobacillaceae sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0044464,GO:0051301,GO:0071840,GO:0071944,GO:0090529 ko:K09772 ko00000,ko03036 Bacteria 1VER3@1239,3F7MQ@33958,4HKIC@91061,COG1799@1,COG1799@2 NA|NA|NA D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA GOKNOHPG_00993 272621.LBA0812 4.7e-220 770.4 Lactobacillaceae ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Bacteria 1TP6W@1239,3F4V1@33958,4H9WZ@91061,COG0206@1,COG0206@2 NA|NA|NA D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity GOKNOHPG_00994 405566.lhv_0858 3.4e-234 817.4 Lactobacillaceae ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Bacteria 1TP1Z@1239,3F413@33958,4H9NF@91061,COG0849@1,COG0849@2 NA|NA|NA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring GOKNOHPG_00995 405566.lhv_0857 7e-129 466.8 Lactobacillaceae divIB ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Bacteria 1V6V5@1239,3F406@33958,4HDFD@91061,COG1589@1,COG1589@2 NA|NA|NA D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex GOKNOHPG_00996 405566.lhv_0856 2.3e-209 734.6 Lactobacillaceae murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 GT28 iLJ478.TM0232,iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089 Bacteria 1TQFT@1239,3F4FW@33958,4HBAQ@91061,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) GOKNOHPG_00997 326425.lhe_0825 8.9e-259 899.0 Lactobacillaceae murD 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TQ3P@1239,3F49W@33958,4HA5P@91061,COG0771@1,COG0771@2 NA|NA|NA M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) GOKNOHPG_00998 405566.lhv_0854 4.6e-177 627.1 Lactobacillaceae mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Bacteria 1TP8W@1239,3F3YP@33958,4H9TP@91061,COG0472@1,COG0472@2 NA|NA|NA M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan GOKNOHPG_00999 1423748.BALB01000001_gene45 0.0 1261.9 Lactobacillaceae ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 1TP93@1239,3F47N@33958,4H9VQ@91061,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein GOKNOHPG_01000 326425.lhe_0822 1.9e-51 208.4 Lactobacillaceae ftsL Bacteria 1VCE5@1239,3F6KG@33958,4HM4W@91061,COG4839@1,COG4839@2 NA|NA|NA D Cell division protein FtsL GOKNOHPG_01001 326425.lhe_0821 2.2e-182 644.8 Lactobacillaceae rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 1TNZV@1239,3F3MF@33958,4H9U2@91061,COG0275@1,COG0275@2 NA|NA|NA J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA GOKNOHPG_01002 326425.lhe_0820 9.1e-77 292.7 Lactobacillaceae mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 ko:K03925 ko00000 Bacteria 1V3JD@1239,3F6K3@33958,4HH23@91061,COG2001@1,COG2001@2 NA|NA|NA K Belongs to the MraZ family GOKNOHPG_01003 349123.Lreu23DRAFT_3295 1.9e-157 562.4 Lactobacillaceae Bacteria 1TSH6@1239,3F5HS@33958,4HEX8@91061,COG3385@1,COG3385@2 NA|NA|NA L PFAM transposase, IS4 family protein GOKNOHPG_01004 326425.lhe_0819 7.1e-53 213.0 Lactobacillaceae Bacteria 1U6DY@1239,2A5PG@1,30UEB@2,3F7PE@33958,4IG5S@91061 NA|NA|NA S Protein of unknown function (DUF3397) GOKNOHPG_01005 326425.lhe_0818 6.5e-13 79.0 Lactobacillaceae Bacteria 1TV7P@1239,29GVY@1,303TQ@2,3F8AT@33958,4I8MD@91061 NA|NA|NA S Protein of unknown function (DUF4044) GOKNOHPG_01006 326425.lhe_0817 3.8e-96 357.5 Lactobacillaceae mreD ko:K03571 ko00000,ko03036 9.B.157.1 Bacteria 1U5E6@1239,29NQT@1,309NS@2,3F5PM@33958,4IF5G@91061 NA|NA|NA GOKNOHPG_01007 405566.lhv_0846 3.7e-146 524.2 Lactobacillaceae mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 ko:K03570 ko00000,ko03036 9.B.157.1 Bacteria 1TR1V@1239,3F3MC@33958,4HB0K@91061,COG1792@1,COG1792@2 NA|NA|NA M Involved in formation and maintenance of cell shape GOKNOHPG_01008 326425.lhe_0815 4.6e-172 610.5 Lactobacillaceae mreB ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 1TP51@1239,3F3ZV@33958,4HA4S@91061,COG1077@1,COG1077@2 NA|NA|NA D cell shape determining protein MreB GOKNOHPG_01009 326425.lhe_0814 2.1e-114 418.3 Lactobacillaceae radC ko:K03630 ko00000 Bacteria 1TQ3K@1239,3F5IM@33958,4HB1W@91061,COG2003@1,COG2003@2 NA|NA|NA L DNA repair protein GOKNOHPG_01010 326425.lhe_0813 5.7e-126 456.8 Lactobacillaceae Bacteria 1V1N8@1239,3F56K@33958,4HG58@91061,COG0637@1,COG0637@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase GOKNOHPG_01011 405566.lhv_0842 7.5e-236 822.8 Lactobacillaceae folC 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0166 Bacteria 1TPX5@1239,3F498@33958,4HBJM@91061,COG0285@1,COG0285@2 NA|NA|NA H Belongs to the folylpolyglutamate synthase family GOKNOHPG_01012 405566.lhv_0841 0.0 1819.7 Lactobacillaceae valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iLJ478.TM1817 Bacteria 1TPN4@1239,3F3RB@33958,4HB85@91061,COG0525@1,COG0525@2 NA|NA|NA J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner GOKNOHPG_01013 525365.HMPREF0548_1177 1.7e-38 164.9 Lactobacillaceae Bacteria 1VBKC@1239,3F782@33958,4IFXG@91061,COG1733@1,COG1733@2 NA|NA|NA K HxlR-like helix-turn-helix GOKNOHPG_01014 405566.lhv_1193 0.0 1743.8 Lactobacillaceae ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 iJN678.ppc,iSFV_1184.SFV_4025 Bacteria 1TQB6@1239,3F4BB@33958,4HCAF@91061,COG2352@1,COG2352@2 NA|NA|NA H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle GOKNOHPG_01015 326425.lhe_1083 3.8e-187 660.6 Lactobacillaceae Bacteria 1V4BS@1239,3F3QN@33958,4HJRT@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase GOKNOHPG_01016 326425.lhe_1082 4.5e-274 949.9 Lactobacillaceae pepV 3.5.1.18 ko:K01270,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 M00016 R00899,R02734,R04951 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPEG@1239,3F3UV@33958,4HC14@91061,COG0624@1,COG0624@2 NA|NA|NA E dipeptidase PepV GOKNOHPG_01017 405566.lhv_1541 3.1e-105 387.9 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3FCFA@33958,4HC8M@91061,COG2801@1,COG2801@2 NA|NA|NA L COG2963 Transposase and inactivated derivatives GOKNOHPG_01018 405566.lhv_1541 5.1e-113 413.7 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3FCFA@33958,4HC8M@91061,COG2801@1,COG2801@2 NA|NA|NA L COG2963 Transposase and inactivated derivatives GOKNOHPG_01020 1423748.BALB01000033_gene1951 1.1e-31 142.1 Lactobacillaceae tdh 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPWP@1239,3F3WG@33958,4HABC@91061,COG1063@1,COG1063@2 NA|NA|NA C Zinc-binding dehydrogenase GOKNOHPG_01021 1423748.BALB01000033_gene1951 7.4e-83 313.2 Lactobacillaceae tdh 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPWP@1239,3F3WG@33958,4HABC@91061,COG1063@1,COG1063@2 NA|NA|NA C Zinc-binding dehydrogenase GOKNOHPG_01022 1423724.BAMM01000002_gene398 2.5e-16 91.3 Lactobacillaceae Bacteria 1VX0V@1239,2F603@1,33YIJ@2,3F6YU@33958,4HXF9@91061 NA|NA|NA GOKNOHPG_01024 1158601.I585_02393 2.3e-29 135.2 Enterococcaceae ubiX GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3JV@1239,4B0F1@81852,4HFZX@91061,COG0163@1,COG0163@2 NA|NA|NA H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN GOKNOHPG_01025 936140.AEOT01000026_gene811 1.6e-104 385.6 Lactobacillaceae ubiX GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129,4.1.1.98 ko:K03182,ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ6V@1239,3F50J@33958,4HM1D@91061,COG0043@1,COG0043@2,COG0163@1,COG0163@2 NA|NA|NA H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase GOKNOHPG_01026 314315.LCA_0579 3.8e-07 60.8 Lactobacillaceae ko:K09681 ko00000,ko03000 Bacteria 1TQ6Y@1239,3F4CY@33958,4HWQQ@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain GOKNOHPG_01027 756499.Desde_1559 2.5e-08 64.3 Peptococcaceae Bacteria 1TQ6Y@1239,25M84@186801,263JF@186807,COG0583@1,COG0583@2 NA|NA|NA K PFAM Bacterial regulatory helix-turn-helix protein, lysR family GOKNOHPG_01028 1140001.I571_01003 8.9e-73 280.0 Enterococcaceae ko:K07150 ko00000 Bacteria 1TQWV@1239,4AZQN@81852,4HEYY@91061,COG1811@1,COG1811@2 NA|NA|NA S Protein of unknown function (DUF554) GOKNOHPG_01029 405566.lhv_1189 3.2e-240 837.4 Lactobacillaceae brnQ GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 ko:K03311 ko00000 2.A.26 Bacteria 1TQIS@1239,3F3KC@33958,4HAKA@91061,COG1114@1,COG1114@2 NA|NA|NA U Component of the transport system for branched-chain amino acids GOKNOHPG_01030 326425.lhe_1080 5.4e-47 193.4 Lactobacillaceae Bacteria 1U7WD@1239,2BN3Q@1,32GQJ@2,3FA99@33958,4IHTS@91061 NA|NA|NA GOKNOHPG_01031 525365.HMPREF0548_1061 2e-141 508.4 Lactobacillaceae malY 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 Bacteria 1TP5G@1239,3F4JX@33958,4H9PE@91061,COG1168@1,COG1168@2 NA|NA|NA E Aminotransferase, class I GOKNOHPG_01032 1423748.BALB01000033_gene1959 8.8e-37 159.1 Lactobacillaceae Bacteria 1U6BF@1239,29PA0@1,30A85@2,3F7IE@33958,4IG31@91061 NA|NA|NA GOKNOHPG_01033 326425.lhe_1077 8e-102 376.3 Lactobacillaceae ko:K07038 ko00000 Bacteria 1TV5H@1239,3F689@33958,4ICPV@91061,COG1988@1,COG1988@2 NA|NA|NA S LexA-binding, inner membrane-associated putative hydrolase GOKNOHPG_01034 1423748.BALB01000020_gene1596 1.1e-15 88.6 Lactobacillaceae Bacteria 1U6M0@1239,29PHT@1,30AFY@2,3F84R@33958,4IGDT@91061 NA|NA|NA GOKNOHPG_01036 405566.lhv_1180 1.2e-91 342.4 Lactobacillaceae hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 Bacteria 1V1C9@1239,3F3K3@33958,4HFZ2@91061,COG0634@1,COG0634@2 NA|NA|NA F Belongs to the purine pyrimidine phosphoribosyltransferase family GOKNOHPG_01037 525365.HMPREF0548_1117 1.7e-255 888.3 Lactobacillaceae Bacteria 1TQJ0@1239,3F4C3@33958,4H9P7@91061,COG1288@1,COG1288@2 NA|NA|NA S C4-dicarboxylate anaerobic carrier GOKNOHPG_01038 1423767.BALU01000003_gene1012 7.1e-11 72.8 Lactobacillaceae Bacteria 1U5CG@1239,29V6Q@1,309MR@2,3F5IP@33958,4IF3N@91061 NA|NA|NA GOKNOHPG_01039 1423748.BALB01000033_gene1964 5.4e-18 96.3 Lactobacillaceae Bacteria 1U5CG@1239,29V6Q@1,309MR@2,3F5IP@33958,4IF3N@91061 NA|NA|NA GOKNOHPG_01040 1423748.BALB01000033_gene1964 7e-54 216.5 Lactobacillaceae Bacteria 1U5CG@1239,29V6Q@1,309MR@2,3F5IP@33958,4IF3N@91061 NA|NA|NA GOKNOHPG_01041 97137.C821_00801 6.7e-11 72.4 Lactobacillaceae merA GO:0000302,GO:0000305,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0019725,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901530,GO:1901700,GO:1990748 1.16.1.1,1.8.1.7 ko:K00383,ko:K00520,ko:K21739 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1TP1W@1239,3FC6T@33958,4HBZF@91061,COG1249@1,COG1249@2 NA|NA|NA C Pyridine nucleotide-disulfide oxidoreductase GOKNOHPG_01042 353496.LBU_0210 2.8e-238 830.9 Lactobacillaceae ko:K09384 ko00000 Bacteria 1TPQU@1239,3F47M@33958,4HBI0@91061,COG3410@1,COG3410@2 NA|NA|NA N Uncharacterized conserved protein (DUF2075) GOKNOHPG_01043 525365.HMPREF0548_1074 1.9e-35 154.8 Lactobacillaceae mmuP GO:0000096,GO:0000097,GO:0000100,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0015806,GO:0016020,GO:0016053,GO:0019752,GO:0022857,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682 ko:K02205,ko:K03293,ko:K16235,ko:K16236 ko00000,ko02000 2.A.3.1,2.A.3.1.10 Bacteria 1UHNR@1239,3F4BG@33958,4HUT7@91061,COG0833@1,COG0833@2 NA|NA|NA E amino acid GOKNOHPG_01044 353496.LBU_0209 4.9e-31 139.8 Lactobacillaceae mmuP GO:0000096,GO:0000097,GO:0000100,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0015806,GO:0016020,GO:0016053,GO:0019752,GO:0022857,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682 ko:K02205,ko:K03293,ko:K16235,ko:K16236 ko00000,ko02000 2.A.3.1,2.A.3.1.10 Bacteria 1UHNR@1239,3F4BG@33958,4HUT7@91061,COG0833@1,COG0833@2 NA|NA|NA E amino acid GOKNOHPG_01045 353496.LBU_0209 4.3e-77 293.9 Lactobacillaceae mmuP GO:0000096,GO:0000097,GO:0000100,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0015806,GO:0016020,GO:0016053,GO:0019752,GO:0022857,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682 ko:K02205,ko:K03293,ko:K16235,ko:K16236 ko00000,ko02000 2.A.3.1,2.A.3.1.10 Bacteria 1UHNR@1239,3F4BG@33958,4HUT7@91061,COG0833@1,COG0833@2 NA|NA|NA E amino acid GOKNOHPG_01046 405566.lhv_1172 1.3e-60 238.8 Lactobacillaceae mmuM GO:0003674,GO:0003824,GO:0005488,GO:0006575,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008270,GO:0008757,GO:0008898,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033477,GO:0033554,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:1901564 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHQ5@1239,3F4UT@33958,4HAS6@91061,COG2040@1,COG2040@2 NA|NA|NA H homocysteine S-methyltransferase GOKNOHPG_01047 525365.HMPREF0548_0256 3.7e-102 377.9 Lactobacillaceae Bacteria 1W1FZ@1239,2FIUN@1,34AK2@2,3F4EU@33958,4HYXZ@91061 NA|NA|NA GOKNOHPG_01048 326425.lhe_1399 2e-26 124.8 Lactobacillaceae Bacteria 1W1FZ@1239,2FIUN@1,34AK2@2,3F4EU@33958,4HYXZ@91061 NA|NA|NA GOKNOHPG_01049 1423767.BALU01000009_gene485 3.3e-22 110.9 Lactobacillaceae Bacteria 1W1FZ@1239,2FIUN@1,34AK2@2,3F4EU@33958,4HYXZ@91061 NA|NA|NA GOKNOHPG_01050 405566.lhv_1486 1.6e-81 309.3 Lactobacillaceae Bacteria 1U575@1239,29NM6@1,309J4@2,3F507@33958,4IEYP@91061 NA|NA|NA GOKNOHPG_01051 405566.lhv_1487 5.6e-124 450.3 Lactobacillaceae dkgA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 1U59X@1239,3F5BI@33958,4IF1F@91061,COG0656@1,COG0656@2 NA|NA|NA S L-ascorbic acid biosynthetic process GOKNOHPG_01052 326425.lhe_1402 6e-70 270.0 Lactobacillaceae Bacteria 1VN90@1239,3F6MQ@33958,4HRIC@91061,COG1765@1,COG1765@2 NA|NA|NA O OsmC-like protein GOKNOHPG_01053 405566.lhv_1489 1.3e-205 722.2 Lactobacillaceae Bacteria 1TQHD@1239,3F43Q@33958,4HX8J@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GOKNOHPG_01054 1423748.BALB01000003_gene466 2.8e-116 424.9 Lactobacillaceae sptS 2.7.13.3 ko:K11328 ko02020,map02020 M00464 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1UHQH@1239,3F4JY@33958,4HAHG@91061,COG0642@1,COG0642@2 NA|NA|NA T Histidine kinase GOKNOHPG_01055 1423748.BALB01000003_gene466 7.5e-61 240.0 Lactobacillaceae sptS 2.7.13.3 ko:K11328 ko02020,map02020 M00464 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1UHQH@1239,3F4JY@33958,4HAHG@91061,COG0642@1,COG0642@2 NA|NA|NA T Histidine kinase GOKNOHPG_01056 1423748.BALB01000003_gene465 2.2e-64 251.9 Lactobacillaceae Bacteria 1TPU2@1239,3F53G@33958,4HG2E@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator GOKNOHPG_01057 405566.lhv_1499 4.5e-196 690.3 Lactobacillaceae galM 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQGJ@1239,3F48R@33958,4HADZ@91061,COG2017@1,COG2017@2 NA|NA|NA G Catalyzes the interconversion of alpha and beta anomers of maltose GOKNOHPG_01058 326425.lhe_1409 6.5e-284 982.6 Lactobacillaceae galT 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPBN@1239,3F4D8@33958,4HAYJ@91061,COG4468@1,COG4468@2 NA|NA|NA G UDP-glucose--hexose-1-phosphate uridylyltransferase GOKNOHPG_01059 405566.lhv_1501 1.3e-221 775.4 Lactobacillaceae galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TPD0@1239,3F3Q9@33958,4HARP@91061,COG0153@1,COG0153@2 NA|NA|NA F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) GOKNOHPG_01061 1033837.WANG_0664 2.7e-137 494.6 Lactobacillaceae Bacteria 1UZVH@1239,2BVJW@1,32QXP@2,3F54U@33958,4HFK6@91061 NA|NA|NA S Uncharacterised protein family (UPF0236) GOKNOHPG_01062 1033837.WANG_1439 3e-89 334.7 Lactobacillaceae Bacteria 1UZVH@1239,2BVJW@1,32QXP@2,3F54U@33958,4HFK6@91061 NA|NA|NA S Uncharacterised protein family (UPF0236) GOKNOHPG_01063 1071400.LBUCD034_1016 1e-53 216.5 Lactobacillaceae tnp2PF3 Bacteria 1U5ZT@1239,3F6RW@33958,4IFNT@91061,COG3293@1,COG3293@2 NA|NA|NA L Putative transposase of IS4/5 family (DUF4096) GOKNOHPG_01064 405566.lhv_0606 3.8e-246 857.1 Lactobacillaceae XK27_08635 ko:K09157 ko00000 Bacteria 1TQG8@1239,3F4H2@33958,4HBTU@91061,COG2848@1,COG2848@2 NA|NA|NA S UPF0210 protein GOKNOHPG_01065 1071400.LBUCD034_0849 8.6e-41 172.6 Lactobacillaceae gcvR ko:K07166 ko00000 Bacteria 1VENW@1239,3F811@33958,4HNJ4@91061,COG3830@1,COG3830@2 NA|NA|NA T Belongs to the UPF0237 family GOKNOHPG_01066 1033837.WANG_1409 1.9e-78 298.5 Lactobacillaceae Bacteria 1UZVH@1239,2BVJW@1,32QXP@2,3F54U@33958,4HFK6@91061 NA|NA|NA S Uncharacterised protein family (UPF0236) GOKNOHPG_01067 908339.HMPREF9265_2037 5.8e-98 363.6 Lactobacillaceae Bacteria 1TQAX@1239,3F429@33958,4HCFF@91061,COG1961@1,COG1961@2 NA|NA|NA L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed GOKNOHPG_01068 326425.lhe_1749 1.7e-12 77.8 Lactobacillaceae Bacteria 1TRZH@1239,3F4XU@33958,4HE9W@91061,COG1002@1,COG1002@2 NA|NA|NA V Type II restriction enzyme, methylase subunits GOKNOHPG_01069 1423767.BALU01000003_gene1088 1.7e-52 212.2 Lactobacillaceae 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1V8PX@1239,3FC6S@33958,4HJXV@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain GOKNOHPG_01070 888064.HMPREF9088_1779 1.8e-18 98.6 Enterococcaceae 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1TT28@1239,4B6G4@81852,4HHZM@91061,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain GOKNOHPG_01071 1227266.HMPREF1551_00339 5.6e-62 244.6 Capnocytophaga Bacteria 1ESZ5@1016,1IFG8@117743,28JU1@1,2Z9J4@2,4NV4K@976 NA|NA|NA S GIY-YIG catalytic domain GOKNOHPG_01072 764291.STRUR_2279 1.4e-44 185.3 Bacilli Bacteria 1W3Q6@1239,294UX@1,2ZS82@2,4I1T5@91061 NA|NA|NA S Domain of unknown function (DUF4298) GOKNOHPG_01075 797515.HMPREF9103_01291 7.9e-11 72.4 Lactobacillaceae hprA 1.1.1.29 ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCX@1239,3F4Z6@33958,4HASY@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family GOKNOHPG_01076 1033837.WANG_1734 5.6e-115 420.6 Lactobacillaceae Bacteria 1V3YR@1239,2BVD0@1,32QT1@2,3F67T@33958,4HK85@91061 NA|NA|NA GOKNOHPG_01077 405566.lhv_0486 2.2e-55 221.5 Lactobacillaceae maa Bacteria 1TSQQ@1239,3F73Z@33958,4HJJ7@91061,COG0110@1,COG0110@2 NA|NA|NA S transferase hexapeptide repeat GOKNOHPG_01078 405566.lhv_0487 3.7e-233 813.9 Lactobacillaceae cycA GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease GOKNOHPG_01079 326425.lhe_0498 0.0 1719.5 Lactobacillaceae adhE 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 Bacteria 1TPB4@1239,3F3RN@33958,4HAN8@91061,COG1012@1,COG1012@2,COG1454@1,COG1454@2 NA|NA|NA C belongs to the iron- containing alcohol dehydrogenase family GOKNOHPG_01080 326425.lhe_0499 0.0 1183.7 Lactobacillaceae glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 iNJ661.Rv3436c,iSB619.SA_RS11245,iYO844.BSU01780 Bacteria 1TPGU@1239,3F467@33958,4H9R4@91061,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source GOKNOHPG_01081 326425.lhe_0500 8e-39 166.0 Lactobacillaceae Bacteria 1U7QQ@1239,29Q9E@1,30B8I@2,3FA10@33958,4IHN0@91061 NA|NA|NA GOKNOHPG_01082 405566.lhv_0493 1.8e-99 368.6 Lactobacillaceae yagE Bacteria 1UZNT@1239,3F3SX@33958,4HFMI@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid GOKNOHPG_01083 405566.lhv_0496 6.3e-92 344.0 Lactobacillaceae Bacteria 1U7M2@1239,2BJNP@1,32E07@2,3F9W4@33958,4IHI5@91061 NA|NA|NA S LPXTG cell wall anchor motif GOKNOHPG_01084 326425.lhe_0503 5.4e-220 770.0 Lactobacillaceae ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0409 Bacteria 1TQ22@1239,3F48Z@33958,4HA7K@91061,COG0282@1,COG0282@2 NA|NA|NA F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction GOKNOHPG_01085 326425.lhe_0504 1.3e-131 475.7 Lactobacillaceae 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R03470 RC00938 ko00000,ko00001,ko01000 Bacteria 1TQGP@1239,3FBCM@33958,4HH3D@91061,COG0599@1,COG0599@2 NA|NA|NA S Carboxymuconolactone decarboxylase family GOKNOHPG_01086 1423748.BALB01000025_gene1778 6.4e-37 159.5 Lactobacillaceae Bacteria 1U6B8@1239,29PH8@1,30A80@2,3F7HY@33958,4IG2S@91061 NA|NA|NA GOKNOHPG_01088 1423748.BALB01000025_gene1782 0.0 1104.4 Lactobacillaceae pckA 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPXB@1239,3F4N4@33958,4IS6N@91061,COG1866@1,COG1866@2 NA|NA|NA H Phosphoenolpyruvate carboxykinase GOKNOHPG_01089 1423748.BALB01000025_gene1783 1.3e-252 879.0 Lactobacillaceae Bacteria 1V2H3@1239,28PUF@1,2ZCFF@2,3F3KN@33958,4HRKS@91061 NA|NA|NA S TerB-C domain GOKNOHPG_01090 1423748.BALB01000025_gene1785 3.3e-250 870.5 Lactobacillaceae Bacteria 1TQPH@1239,3F54M@33958,4HCUW@91061,COG1135@1,COG1135@2 NA|NA|NA P P-loop Domain of unknown function (DUF2791) GOKNOHPG_01091 1423748.BALB01000025_gene1786 0.0 1492.6 Lactobacillaceae lhr ko:K03724 ko00000,ko01000,ko03400 Bacteria 1UHYQ@1239,3F42E@33958,4HD4E@91061,COG1201@1,COG1201@2 NA|NA|NA L DEAD DEAH box helicase GOKNOHPG_01092 326425.lhe_0509 3.3e-59 234.2 Lactobacillaceae Bacteria 1U61M@1239,29P2Q@1,30A0W@2,3F6U2@33958,4IFQH@91061 NA|NA|NA GOKNOHPG_01093 326425.lhe_0510 1.5e-138 498.8 Lactobacillaceae Bacteria 1TSFT@1239,3F6RG@33958,4HGDA@91061,COG4295@1,COG4295@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2263) GOKNOHPG_01094 1423748.BALB01000005_gene646 3.3e-32 144.4 Lactobacillaceae 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TYDT@1239,3FBWF@33958,4HB9Z@91061,COG5464@1,COG5464@2 NA|NA|NA S PD-(D/E)XK nuclease family transposase GOKNOHPG_01097 326425.lhe_0907 1.2e-86 326.2 Lactobacillaceae metI ko:K02072 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TRSY@1239,3F48A@33958,4HBEV@91061,COG2011@1,COG2011@2 NA|NA|NA P ABC transporter permease GOKNOHPG_01098 405566.lhv_0961 4.1e-187 660.6 Lactobacillaceae metN ko:K02071 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TPPN@1239,3F3U5@33958,4H9VX@91061,COG1135@1,COG1135@2 NA|NA|NA P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system GOKNOHPG_01099 405566.lhv_0960 9.1e-161 572.8 Lactobacillaceae metQ1 ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TQAS@1239,3F3WP@33958,4HCTA@91061,COG1464@1,COG1464@2 NA|NA|NA P Belongs to the nlpA lipoprotein family GOKNOHPG_01100 405566.lhv_0959 0.0 1387.1 Lactobacillaceae aha1 ko:K12952 ko00000,ko01000 3.A.3.23 Bacteria 1TPF5@1239,3F4Y1@33958,4H9ZI@91061,COG0474@1,COG0474@2 NA|NA|NA P E1-E2 ATPase GOKNOHPG_01101 326425.lhe_0902 8.9e-95 352.8 Lactobacillaceae folA 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 Bacteria 1VB80@1239,3F6Y4@33958,4HIGJ@91061,COG0262@1,COG0262@2 NA|NA|NA H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis GOKNOHPG_01102 326425.lhe_0901 4.5e-185 653.7 Lactobacillaceae thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSIR@1239,3F3SB@33958,4H9QS@91061,COG0207@1,COG0207@2 NA|NA|NA F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis GOKNOHPG_01103 405566.lhv_0954 1.2e-36 158.7 Lactobacillaceae yifK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03293 ko00000 2.A.3.1 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease GOKNOHPG_01104 405566.lhv_0954 4.5e-181 640.6 Lactobacillaceae yifK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03293 ko00000 2.A.3.1 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease GOKNOHPG_01105 405566.lhv_0953 8.4e-63 246.1 Lactobacillaceae Bacteria 1TUVJ@1239,3F8JH@33958,4IE4X@91061,COG1598@1,COG1598@2 NA|NA|NA S PFAM Uncharacterised protein family UPF0150 GOKNOHPG_01107 891391.LAC30SC_04505 6.1e-56 223.8 Lactobacillaceae cbh 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 1TPZS@1239,3F4NH@33958,4HC4Y@91061,COG3049@1,COG3049@2 NA|NA|NA M Linear amide C-N hydrolase, choloylglycine hydrolase family protein GOKNOHPG_01108 272621.LBA0892 5.5e-54 216.9 Lactobacillaceae cbh 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 1TPZS@1239,3F4NH@33958,4HC4Y@91061,COG3049@1,COG3049@2 NA|NA|NA M Linear amide C-N hydrolase, choloylglycine hydrolase family protein GOKNOHPG_01109 405566.lhv_0949 2.3e-99 368.2 Lactobacillaceae 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1U506@1239,3F3M2@33958,4IES2@91061,COG0671@1,COG0671@2 NA|NA|NA I Acid phosphatase homologues GOKNOHPG_01110 748671.LCRIS_00904 2.5e-131 474.9 Lactobacillaceae yitS Bacteria 1V0RC@1239,3F4PM@33958,4HBSA@91061,COG1307@1,COG1307@2 NA|NA|NA S Uncharacterised protein, DegV family COG1307 GOKNOHPG_01111 326425.lhe_0896 3.1e-245 854.0 Lactobacillaceae eno GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0043236,GO:0050840 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 1V12I@1239,3FCCA@33958,4HTD2@91061,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis GOKNOHPG_01112 326425.lhe_0895 2.9e-65 255.0 Lactobacillaceae Bacteria 1VZSI@1239,29W71@1,30HS8@2,3F6RP@33958,4IFNQ@91061 NA|NA|NA S Domain of unknown function (DUF4767) GOKNOHPG_01113 405566.lhv_0943 1.6e-85 322.0 Lactobacillaceae Bacteria 1UYXM@1239,3F667@33958,4HD96@91061,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase GOKNOHPG_01114 1423748.BALB01000019_gene1559 1.8e-148 531.9 Lactobacillaceae ypbG 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1UZ80@1239,3FBD4@33958,4HD5J@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family GOKNOHPG_01115 326425.lhe_0892 6.6e-10 68.6 Lactobacillaceae pbg6 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3FC7C@33958,4HDER@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family GOKNOHPG_01116 1423748.BALB01000019_gene1560 1.5e-28 131.3 Lactobacillaceae pbg6 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3FC7C@33958,4HDER@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family GOKNOHPG_01117 1033837.WANG_0770 5.8e-154 550.1 Lactobacillaceae pbg6 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3FC7C@33958,4HDER@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family GOKNOHPG_01118 748671.LCRIS_00898 1.9e-75 288.9 Lactobacillaceae lacE ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 Bacteria 1VTVX@1239,3FC6X@33958,4HFKM@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane GOKNOHPG_01119 891391.LAC30SC_04455 2.6e-91 341.7 Lactobacillaceae pts23C ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 Bacteria 1VTVX@1239,3FC6X@33958,4HFKM@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane GOKNOHPG_01120 1033837.WANG_0771 7.2e-135 486.5 Lactobacillaceae gmuR ko:K03492,ko:K03710 ko00000,ko03000 Bacteria 1V0UW@1239,3FC8M@33958,4HD10@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA GOKNOHPG_01121 1423767.BALU01000002_gene1649 6.6e-292 1009.2 Lactobacillaceae 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family GOKNOHPG_01122 1069534.LRC_10250 8e-44 184.1 Lactobacillaceae cas6 ko:K19091 ko00000,ko01000,ko02048 Bacteria 1U7RP@1239,3FA2Q@33958,4IHP0@91061,COG1583@1,COG1583@2 NA|NA|NA L CRISPR associated protein Cas6 GOKNOHPG_01123 1069534.LRC_10240 4.5e-106 392.1 Lactobacillaceae cst1 ko:K19088 ko00000,ko02048 Bacteria 1TPRZ@1239,28HTI@1,2Z80D@2,3F9R1@33958,4HCA6@91061 NA|NA|NA S CRISPR-associated protein (Cas_CXXC_CXXC) GOKNOHPG_01124 1069534.LRC_10230 1.8e-103 382.5 Lactobacillaceae cst2 ko:K19075 ko00000,ko02048 Bacteria 1TRGS@1239,3F9XP@33958,4HEVR@91061,COG1857@1,COG1857@2 NA|NA|NA L CRISPR-associated negative auto-regulator DevR/Csa2 GOKNOHPG_01125 1423806.JCM15457_530 1.4e-66 259.6 Lactobacillaceae cas5t ko:K19090 ko00000,ko02048 Bacteria 1UYJD@1239,3F9RR@33958,4HGCF@91061,COG1688@1,COG1688@2 NA|NA|NA L CRISPR-associated protein Cas5 GOKNOHPG_01126 1069534.LRC_10210 1.9e-179 636.3 Lactobacillaceae cas3 ko:K07012 ko00000,ko01000,ko02048 Bacteria 1TQ9B@1239,3F4VV@33958,4HAH7@91061,COG1203@1,COG1203@2 NA|NA|NA L CRISPR-associated helicase cas3 GOKNOHPG_01127 1069534.LRC_10200 5.4e-49 200.7 Lactobacillaceae cas4 3.1.12.1 ko:K07464 ko00000,ko01000,ko02048 Bacteria 1V781@1239,3F9SX@33958,4IHG2@91061,COG1468@1,COG1468@2 NA|NA|NA L Domain of unknown function DUF83 GOKNOHPG_01128 1069534.LRC_10190 5.1e-123 447.6 Lactobacillaceae cas1 ko:K15342 ko00000,ko02048,ko03400 Bacteria 1TQWG@1239,3FBCR@33958,4HDKV@91061,COG1518@1,COG1518@2 NA|NA|NA L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette GOKNOHPG_01129 1423806.JCM15457_525 1e-28 132.5 Bacilli cas2 ko:K09951 ko00000,ko02048 Bacteria 1VAV3@1239,4HKKP@91061,COG1343@1,COG1343@2 NA|NA|NA L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette GOKNOHPG_01130 405566.lhv_1617 0.0 1714.1 Lactobacillaceae polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1TPKJ@1239,3F3ZA@33958,4H9S7@91061,COG0258@1,COG0258@2,COG0749@1,COG0749@2 NA|NA|NA L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity GOKNOHPG_01131 326425.lhe_1494 3.5e-157 560.8 Lactobacillaceae fpg 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPM9@1239,3F43E@33958,4H9Q7@91061,COG0266@1,COG0266@2 NA|NA|NA L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates GOKNOHPG_01132 326425.lhe_1493 4.2e-104 384.0 Lactobacillaceae coaE 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6FS@1239,3F6WF@33958,4HII3@91061,COG0237@1,COG0237@2 NA|NA|NA F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A GOKNOHPG_01133 326425.lhe_1492 6.6e-81 306.6 Lactobacillaceae nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K07738 ko00000,ko03000 Bacteria 1V3JA@1239,3F65S@33958,4HGXA@91061,COG1327@1,COG1327@2 NA|NA|NA K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes GOKNOHPG_01134 326425.lhe_1491 1.2e-244 852.0 Lactobacillaceae dnaB ko:K03346 ko00000,ko03032 Bacteria 1TSBB@1239,3FB6I@33958,4HE63@91061,COG3611@1,COG3611@2 NA|NA|NA L Replication initiation and membrane attachment GOKNOHPG_01135 326425.lhe_1490 9.9e-166 589.3 Lactobacillaceae dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K11144 ko00000,ko03032 Bacteria 1TPZX@1239,3F4JK@33958,4HABS@91061,COG1484@1,COG1484@2 NA|NA|NA L Primosomal protein DnaI GOKNOHPG_01136 405566.lhv_1611 0.0 1276.5 Lactobacillaceae thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP78@1239,3F3TC@33958,4HABZ@91061,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) GOKNOHPG_01137 326425.lhe_1488 3.7e-88 330.9 Lactobacillaceae Bacteria 1U68M@1239,29NRA@1,30A5W@2,3F7B3@33958,4IFZH@91061 NA|NA|NA GOKNOHPG_01138 405566.lhv_1609 1.1e-95 355.9 Lactobacillaceae Bacteria 1U5FC@1239,29NRA@1,309P8@2,3F5US@33958,4IF6Y@91061 NA|NA|NA GOKNOHPG_01139 326425.lhe_1459 6.9e-38 162.9 Lactobacillaceae Bacteria 1UJGN@1239,3FBV2@33958,4IT9F@91061,COG3620@1,COG3620@2 NA|NA|NA K Helix-turn-helix domain GOKNOHPG_01140 326425.lhe_1460 4.4e-56 223.8 Lactobacillaceae GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0045926,GO:0045927,GO:0046483,GO:0048518,GO:0048519,GO:0050789,GO:0050896,GO:0065007,GO:0070482,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 Bacteria 1VB8K@1239,3F7HF@33958,4HKT7@91061,COG4679@1,COG4679@2 NA|NA|NA S Phage derived protein Gp49-like (DUF891) GOKNOHPG_01141 405566.lhv_1578 6.3e-168 596.7 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1TQIV@1239,3FBIV@33958,4IQTH@91061,COG0039@1,COG0039@2 NA|NA|NA C lactate/malate dehydrogenase, alpha/beta C-terminal domain GOKNOHPG_01142 405566.lhv_1579 4.1e-62 244.2 Lactobacillaceae greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K03624 ko00000,ko03021 Bacteria 1V44S@1239,3F4ZF@33958,4HGZU@91061,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides GOKNOHPG_01143 326425.lhe_1463 0.0 1584.3 Lactobacillaceae pheT GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_2160,iPC815.YPO2428 Bacteria 1TP98@1239,3F3V3@33958,4HAQ9@91061,COG0072@1,COG0072@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily GOKNOHPG_01144 405566.lhv_1581 9e-203 712.6 Lactobacillaceae pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPFW@1239,3F4NT@33958,4HAVN@91061,COG0016@1,COG0016@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily GOKNOHPG_01145 1423748.BALB01000003_gene414 6.7e-62 243.0 Lactobacillaceae yodB Bacteria 1VBI7@1239,3F7FK@33958,4HKBR@91061,COG1733@1,COG1733@2 NA|NA|NA K Transcriptional regulator, HxlR family GOKNOHPG_01146 326425.lhe_1466 5.7e-138 496.9 Lactobacillaceae spoU 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 1V3JP@1239,3F3NF@33958,4HCF5@91061,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family GOKNOHPG_01147 405566.lhv_1584 4.9e-44 183.3 Lactobacillaceae acyP GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036 Bacteria 1VEM9@1239,3F81R@33958,4HNN7@91061,COG1254@1,COG1254@2 NA|NA|NA C Belongs to the acylphosphatase family GOKNOHPG_01148 405566.lhv_1585 3.8e-155 554.3 Lactobacillaceae yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 1TSDN@1239,3F3P3@33958,4HCC8@91061,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins GOKNOHPG_01149 326425.lhe_1469 1.1e-81 309.3 Lactobacillaceae ko:K19055 ko00000,ko01000,ko03016 Bacteria 1V29H@1239,3F6ZD@33958,4HP8F@91061,COG3760@1,COG3760@2 NA|NA|NA S Aminoacyl-tRNA editing domain GOKNOHPG_01150 326425.lhe_1470 4.8e-277 959.9 Lactobacillaceae arlS GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K18940 ko02020,map02020 M00716,M00717 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TPSK@1239,3F3NU@33958,4HAH5@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase GOKNOHPG_01151 326425.lhe_1471 1e-125 456.1 Lactobacillaceae Bacteria 1TS81@1239,3F421@33958,4H9NE@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator GOKNOHPG_01152 405566.lhv_1589 7.8e-97 359.8 Lactobacillaceae yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K07040 ko00000 Bacteria 1VB08@1239,3F61Z@33958,4HME9@91061,COG1399@1,COG1399@2 NA|NA|NA S Uncharacterized ACR, COG1399 GOKNOHPG_01153 405566.lhv_1590 9.5e-214 749.2 Lactobacillaceae ylbM Bacteria 1TPP2@1239,3F3QC@33958,4HAZJ@91061,COG1323@1,COG1323@2 NA|NA|NA S Belongs to the UPF0348 family GOKNOHPG_01154 326425.lhe_1474 4.5e-58 230.3 Lactobacillaceae rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 ko:K09710 ko00000,ko03009 Bacteria 1VA2Z@1239,3F7QN@33958,4HKEJ@91061,COG0799@1,COG0799@2 NA|NA|NA J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation GOKNOHPG_01155 326425.lhe_1475 2.5e-109 401.4 Lactobacillaceae nadD 2.7.6.3,2.7.7.18 ko:K00950,ko:K00969,ko:K06950 ko00760,ko00790,ko01100,map00760,map00790,map01100 M00115,M00126,M00841 R00137,R03005,R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6Y1@1239,3F47C@33958,4HHRY@91061,COG1713@1,COG1713@2 NA|NA|NA H Hydrolase, HD family GOKNOHPG_01156 326425.lhe_1476 2.4e-121 441.4 Lactobacillaceae nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1V3SK@1239,3F4D6@33958,4HGXK@91061,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) GOKNOHPG_01157 405566.lhv_1594 1.1e-211 742.3 Lactobacillaceae yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 ko:K06948 ko00000,ko03009 Bacteria 1TPM2@1239,3F4JU@33958,4HAAF@91061,COG1161@1,COG1161@2 NA|NA|NA S Ribosome biogenesis GTPase YqeH GOKNOHPG_01158 405566.lhv_1595 1.1e-92 345.9 Lactobacillaceae yqeG ko:K07015 ko00000 Bacteria 1V6KM@1239,3F46V@33958,4HGAV@91061,COG2179@1,COG2179@2 NA|NA|NA S HAD phosphatase, family IIIA GOKNOHPG_01159 1423767.BALU01000009_gene397 5.1e-57 226.9 Lactobacillaceae rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6DB@1239,3F6HZ@33958,4HH2W@91061,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit GOKNOHPG_01160 1423748.BALB01000003_gene396 6.9e-27 125.9 Lactobacillaceae rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02916 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VF5W@1239,3F7CQ@33958,4HNIQ@91061,COG0291@1,COG0291@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL35 family GOKNOHPG_01161 326425.lhe_1481 4.8e-55 220.3 Lactobacillaceae infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 1V1RC@1239,3F4MS@33958,4HFUS@91061,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins GOKNOHPG_01162 525365.HMPREF0548_1195 1.9e-162 578.6 Lactobacillaceae Bacteria 1TPC4@1239,3F577@33958,4HJM8@91061,COG1304@1,COG1304@2 NA|NA|NA C FMN-dependent dehydrogenase GOKNOHPG_01163 525365.HMPREF0548_1194 9.3e-135 486.5 Firmicutes ko:K07088 ko00000 Bacteria 1TRAI@1239,COG0679@1,COG0679@2 NA|NA|NA S Transporter, auxin efflux carrier (AEC) family protein GOKNOHPG_01164 326425.lhe_1484 2.6e-19 102.1 Lactobacillaceae Bacteria 1TRFZ@1239,3F4KN@33958,4HEZ0@91061,COG1808@1,COG1808@2 NA|NA|NA S Domain of unknown function (DUF389) GOKNOHPG_01165 326425.lhe_0909 2.5e-26 124.0 Lactobacillaceae Bacteria 1U797@1239,29PZQ@1,30AY5@2,3F957@33958,4IH43@91061 NA|NA|NA GOKNOHPG_01166 405566.lhv_0968 2.6e-266 924.1 Lactobacillaceae fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHPH@1239,3F3K0@33958,4HA6P@91061,COG0114@1,COG0114@2 NA|NA|NA C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate GOKNOHPG_01167 326425.lhe_0911 2.3e-262 911.0 Lactobacillaceae frdC 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAR@1239,3F3KJ@33958,4HAXN@91061,COG1053@1,COG1053@2 NA|NA|NA C FAD binding domain GOKNOHPG_01168 272621.LBA0909 9.7e-107 394.0 Lactobacillaceae ko:K02519 ko00000,ko03012,ko03029 Bacteria 1UJ2C@1239,3FBTV@33958,4ISZG@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein GOKNOHPG_01170 405566.lhv_0978 6.1e-163 580.1 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPSY@1239,3F3RM@33958,4HB0Z@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily. LDH family GOKNOHPG_01171 272621.LBA1634 3.3e-73 283.1 Lactobacillaceae fhaB GO:0005575,GO:0005623,GO:0009986,GO:0044464 ko:K15125,ko:K18491 ko04550,ko05133,map04550,map05133 ko00000,ko00001,ko00536,ko03000 Bacteria 1UHXY@1239,3F52E@33958,4ISAC@91061,COG2373@1,COG2373@2,COG3064@1,COG3064@2 NA|NA|NA M Rib/alpha-like repeat GOKNOHPG_01172 1033837.WANG_0753 3.1e-45 188.7 Lactobacillaceae Bacteria 1UJGB@1239,29X4C@1,30IT6@2,3F6JZ@33958,4IT92@91061 NA|NA|NA GOKNOHPG_01174 405566.lhv_0980 4.7e-43 180.3 Lactobacillaceae Bacteria 1UJGB@1239,29X4C@1,30IT6@2,3F6JZ@33958,4IT92@91061 NA|NA|NA GOKNOHPG_01175 326425.lhe_0914 1.4e-256 891.7 Lactobacillaceae pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 1TRJN@1239,3F5DQ@33958,4HBZ9@91061,COG3579@1,COG3579@2 NA|NA|NA E Peptidase C1-like family GOKNOHPG_01176 405566.lhv_0984 5.3e-270 936.4 Lactobacillaceae ko:K03319 ko00000 2.A.47 Bacteria 1TSGE@1239,3F4RH@33958,4HDE4@91061,COG0471@1,COG0471@2 NA|NA|NA P Sodium:sulfate symporter transmembrane region GOKNOHPG_01177 326425.lhe_0916 1.4e-152 545.4 Lactobacillaceae ydjP Bacteria 1TR25@1239,3F4FI@33958,4HMJ7@91061,COG2267@1,COG2267@2 NA|NA|NA I Alpha/beta hydrolase family GOKNOHPG_01178 326425.lhe_0917 5.3e-195 686.8 Lactobacillaceae citC 6.2.1.22 ko:K01910 ko02020,map02020 R04449 RC00012,RC00039 ko00000,ko00001,ko01000 Bacteria 1TSGQ@1239,3F4H7@33958,4HC6Q@91061,COG3053@1,COG3053@2 NA|NA|NA H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase GOKNOHPG_01179 326425.lhe_0918 9.1e-44 182.6 Lactobacillaceae citD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008815,GO:0009346,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016833,GO:0032991,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 ko:K01646 ko02020,map02020 R00362 RC00067,RC01118 ko00000,ko00001 Bacteria 1VEZZ@1239,3F7FR@33958,4HNXD@91061,COG3052@1,COG3052@2 NA|NA|NA C Covalent carrier of the coenzyme of citrate lyase GOKNOHPG_01180 1423748.BALB01000010_gene1076 9e-167 592.8 Lactobacillaceae citE 4.1.3.25,4.1.3.34 ko:K01644,ko:K18292 ko00660,ko01100,ko02020,map00660,map01100,map02020 R00237,R00362 RC00067,RC00502,RC01118,RC01205 ko00000,ko00001,ko01000 Bacteria 1TPDY@1239,3F47Q@33958,4HD40@91061,COG2301@1,COG2301@2 NA|NA|NA G Belongs to the HpcH HpaI aldolase family GOKNOHPG_01181 405566.lhv_0990 3.9e-287 993.4 Lactobacillaceae citF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.8.3.10 ko:K01643 ko02020,map02020 R00362 RC00067,RC01118 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_0634 Bacteria 1TPN3@1239,3F4EA@33958,4HAE1@91061,COG3051@1,COG3051@2 NA|NA|NA H Citrate (pro-3S)-lyase alpha chain GOKNOHPG_01182 405566.lhv_0991 6.8e-35 153.3 Lactobacillaceae Bacteria 1VNWP@1239,2DBU6@1,2ZB4C@2,3F51G@33958,4HRN6@91061 NA|NA|NA GOKNOHPG_01183 326425.lhe_0921 9.1e-55 219.5 Lactobacillaceae Bacteria 1VNWP@1239,2DBU6@1,2ZB4C@2,3F51G@33958,4HRN6@91061 NA|NA|NA GOKNOHPG_01185 1158602.I590_03070 2.4e-76 291.6 Enterococcaceae M1-431 Bacteria 1TSF1@1239,4B123@81852,4HHG3@91061,COG4283@1,COG4283@2 NA|NA|NA S Protein of unknown function (DUF1706) GOKNOHPG_01187 405566.lhv_0212 1.5e-255 888.3 Lactobacillaceae pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 1TRJN@1239,3F3QA@33958,4HBZ9@91061,COG3579@1,COG3579@2 NA|NA|NA E aminopeptidase GOKNOHPG_01188 1033837.WANG_1818 1.3e-111 409.1 Lactobacillaceae ypgQ ko:K06950 ko00000 Bacteria 1V7IZ@1239,3F3PN@33958,4HIVB@91061,COG1418@1,COG1418@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. GOKNOHPG_01189 326425.lhe_1873 8.5e-207 726.1 Lactobacillaceae guaB GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027 Bacteria 1TNZ1@1239,3F3XN@33958,4H9V3@91061,COG0516@1,COG0516@2 NA|NA|NA F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides GOKNOHPG_01190 326425.lhe_1868 2e-252 877.9 Lactobacillaceae pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 1TRJN@1239,3F3QA@33958,4HBZ9@91061,COG3579@1,COG3579@2 NA|NA|NA E aminopeptidase GOKNOHPG_01191 1423748.BALB01000008_gene944 5.7e-63 246.9 Lactobacillaceae hsp ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 1VG0E@1239,3FB63@33958,4HIUZ@91061,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family GOKNOHPG_01192 405566.lhv_0223 2.6e-77 294.7 Lactobacillaceae greA ko:K03624,ko:K04760 ko00000,ko03021 Bacteria 1V1G3@1239,3F6ZK@33958,4HW8H@91061,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides GOKNOHPG_01193 405566.lhv_0224 3.2e-113 414.5 Lactobacillaceae Bacteria 1UG72@1239,2BFBV@1,3294Z@2,3F5KI@33958,4IF41@91061 NA|NA|NA GOKNOHPG_01195 326425.lhe_1863 1.3e-113 415.6 Lactobacillaceae Bacteria 1TRRV@1239,3F5AJ@33958,4HHE2@91061,COG2135@1,COG2135@2 NA|NA|NA E Belongs to the SOS response-associated peptidase family GOKNOHPG_01196 1423748.BALB01000008_gene948 2.6e-191 674.5 Lactobacillaceae trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPY7@1239,3F3V6@33958,4HA1K@91061,COG0180@1,COG0180@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family GOKNOHPG_01197 326425.lhe_1861 4.7e-90 337.0 Lactobacillaceae comEB 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 Bacteria 1V3PU@1239,3FC8D@33958,4HEJU@91061,COG2131@1,COG2131@2 NA|NA|NA F MafB19-like deaminase GOKNOHPG_01198 405566.lhv_0227 3e-108 397.9 Lactobacillaceae ko:K06872,ko:K07507 ko00000,ko02000 9.B.20 Bacteria 1V5YF@1239,3F5HD@33958,4HJVB@91061,COG1512@1,COG1512@2 NA|NA|NA S TPM domain GOKNOHPG_01199 326425.lhe_1859 0.0 1681.8 Lactobacillaceae mgtA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132 3.6.3.2 ko:K01531 ko00000,ko01000 3.A.3.4 iSF_1195.SF4248 Bacteria 1TPF5@1239,3F4E0@33958,4HBQJ@91061,COG0474@1,COG0474@2 NA|NA|NA P COG0474 Cation transport ATPase GOKNOHPG_01200 405566.lhv_0229 0.0 1326.2 Lactobacillaceae metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPA1@1239,3F3XR@33958,4H9VC@91061,COG0143@1,COG0143@2 NA|NA|NA J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation GOKNOHPG_01201 405566.lhv_0230 2.8e-145 521.2 Lactobacillaceae tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 ko:K03424 ko00000,ko01000 Bacteria 1TNY1@1239,3F3N2@33958,4HA74@91061,COG0084@1,COG0084@2 NA|NA|NA L hydrolase, TatD family GOKNOHPG_01202 326425.lhe_1856 7.2e-98 363.2 Lactobacillaceae rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985,ko:K07476 ko00000,ko01000 Bacteria 1V3K3@1239,3F64F@33958,4HH5Y@91061,COG1658@1,COG1658@2 NA|NA|NA J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step GOKNOHPG_01203 405566.lhv_0232 1.4e-159 568.9 Lactobacillaceae ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528,ko:K15256 R10716 RC00003,RC03257 ko00000,ko01000,ko03009,ko03016 Bacteria 1TP9W@1239,3F3VC@33958,4HA4R@91061,COG0030@1,COG0030@2 NA|NA|NA J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits GOKNOHPG_01204 748671.LCRIS_00221 2.9e-38 164.1 Lactobacillaceae veg Bacteria 1VEQM@1239,3F7D3@33958,4HKF8@91061,COG4466@1,COG4466@2 NA|NA|NA S Biofilm formation stimulator VEG GOKNOHPG_01205 405566.lhv_0234 4.7e-146 523.9 Lactobacillaceae purR 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816,ko:K09685 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko03000,ko04147 Bacteria 1TPN9@1239,3F3NH@33958,4HB8I@91061,COG0503@1,COG0503@2 NA|NA|NA F pur operon repressor GOKNOHPG_01206 1423748.BALB01000008_gene959 4.5e-202 710.7 Lactobacillaceae glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042,ko:K11528 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP88@1239,3F4I3@33958,4H9V5@91061,COG1207@1,COG1207@2 NA|NA|NA M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain GOKNOHPG_01207 326425.lhe_1851 9.6e-30 135.6 Lactobacillaceae Bacteria 1U6AS@1239,2DKPF@1,30A7K@2,3F7GS@33958,4IG26@91061 NA|NA|NA S SLAP domain GOKNOHPG_01208 405566.lhv_0918 7e-175 619.8 Lactobacillaceae iunH 3.2.2.1 ko:K01239,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 Bacteria 1TRGU@1239,3F3V1@33958,4H9TZ@91061,COG1957@1,COG1957@2 NA|NA|NA F inosine-uridine preferring nucleoside hydrolase GOKNOHPG_01209 326425.lhe_0882 7.5e-126 456.4 Lactobacillaceae Bacteria 1TQ12@1239,3F4U1@33958,4HA57@91061,COG4989@1,COG4989@2 NA|NA|NA S Aldo keto reductase GOKNOHPG_01210 1423748.BALB01000019_gene1571 1.5e-35 154.8 Lactobacillaceae celA 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family GOKNOHPG_01211 891391.LAC30SC_04380 6.1e-232 809.7 Lactobacillaceae celA 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family GOKNOHPG_01212 326425.lhe_1434 5.8e-135 486.9 Lactobacillaceae aroD GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25,4.2.1.10 ko:K03785,ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413,R03084 RC00206,RC00848 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSPN@1239,3F4TX@33958,4HDMG@91061,COG0710@1,COG0710@2 NA|NA|NA E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate GOKNOHPG_01213 1033837.WANG_p1133 4.3e-138 497.3 Lactobacillaceae Bacteria 1TP4A@1239,3F40X@33958,4HDAB@91061,COG3547@1,COG3547@2 NA|NA|NA L COG3547 Transposase and inactivated derivatives GOKNOHPG_01214 1033837.WANG_1536 0.0 1079.7 Lactobacillaceae fhs GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP6N@1239,3F3U6@33958,4HA2X@91061,COG2759@1,COG2759@2 NA|NA|NA F Belongs to the formate--tetrahydrofolate ligase family GOKNOHPG_01215 1033837.WANG_1537 6.9e-81 306.6 Lactobacillaceae purE GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551 Bacteria 1V1MV@1239,3F6P0@33958,4HFR7@91061,COG0041@1,COG0041@2 NA|NA|NA F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) GOKNOHPG_01216 1033837.WANG_1538 1.1e-214 752.3 Lactobacillaceae purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQCD@1239,3F3YV@33958,4H9M5@91061,COG0026@1,COG0026@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) GOKNOHPG_01217 1033837.WANG_1539 5.7e-132 476.9 Lactobacillaceae purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016881,GO:0044424,GO:0044444,GO:0044464 4.1.1.21,4.3.2.2,6.3.2.6 ko:K01587,ko:K01756,ko:K01923 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04209,R04559,R04591 RC00064,RC00162,RC00379,RC00444,RC00445,RC00590 ko00000,ko00001,ko00002,ko01000 iAF1260.b2476,iB21_1397.B21_02330,iBWG_1329.BWG_2240,iE2348C_1286.E2348C_2713,iEC042_1314.EC042_2677,iEC55989_1330.EC55989_2759,iECABU_c1320.ECABU_c27880,iECBD_1354.ECBD_1213,iECB_1328.ECB_02368,iECDH10B_1368.ECDH10B_2642,iECDH1ME8569_1439.ECDH1ME8569_2402,iECDH1ME8569_1439.EcDH1_1193,iECD_1391.ECD_02368,iECED1_1282.ECED1_2911,iECH74115_1262.ECH74115_3698,iECIAI1_1343.ECIAI1_2527,iECNA114_1301.ECNA114_2561,iECO103_1326.ECO103_2988,iECO111_1330.ECO111_3199,iECO26_1355.ECO26_3522,iECOK1_1307.ECOK1_2784,iECP_1309.ECP_2490,iECS88_1305.ECS88_2658,iECSE_1348.ECSE_2760,iECSF_1327.ECSF_2329,iECSP_1301.ECSP_3415,iECUMN_1333.ECUMN_2789,iECW_1372.ECW_m2698,iECs_1301.ECs3338,iEKO11_1354.EKO11_1259,iETEC_1333.ETEC_2581,iEcDH1_1363.EcDH1_1193,iEcE24377_1341.EcE24377A_2757,iEcHS_1320.EcHS_A2607,iEcSMS35_1347.EcSMS35_2623,iEcolC_1368.EcolC_1200,iG2583_1286.G2583_2999,iJN746.PP_1240,iJO1366.b2476,iJR904.b2476,iLF82_1304.LF82_1775,iNRG857_1313.NRG857_12360,iSFV_1184.SFV_2521,iSF_1195.SF2519,iSFxv_1172.SFxv_2773,iS_1188.S2669,iSbBS512_1146.SbBS512_E2848,iUMNK88_1353.UMNK88_3071,iWFL_1372.ECW_m2698,iY75_1357.Y75_RS12925,iYL1228.KPN_02810,iZ_1308.Z3735 Bacteria 1TP11@1239,3F44Z@33958,4H9U8@91061,COG0152@1,COG0152@2 NA|NA|NA F Belongs to the SAICAR synthetase family GOKNOHPG_01218 1033837.WANG_1540 2.7e-36 157.5 Lactobacillaceae purS 6.3.2.6,6.3.5.3 ko:K01923,ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463,R04591 RC00010,RC00064,RC00162,RC01160 ko00000,ko00001,ko00002,ko01000 iYO844.BSU06460 Bacteria 1VEH1@1239,3F81F@33958,4HP0E@91061,COG1828@1,COG1828@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL GOKNOHPG_01219 1033837.WANG_1541 7e-124 449.9 Lactobacillaceae purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1B@1239,3F48D@33958,4HAKZ@91061,COG0047@1,COG0047@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL GOKNOHPG_01220 1033837.WANG_1542 0.0 1492.6 Lactobacillaceae purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAS@1239,3F4IQ@33958,4HB3N@91061,COG0046@1,COG0046@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL GOKNOHPG_01221 1033837.WANG_1543 6e-274 949.5 Lactobacillaceae purF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 iSB619.SA_RS05225 Bacteria 1TPH3@1239,3F3U7@33958,4HAXU@91061,COG0034@1,COG0034@2 NA|NA|NA F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine GOKNOHPG_01222 1033837.WANG_1544 1.9e-200 704.9 Lactobacillaceae purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 ko:K01933,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1844,iECSF_1327.ECSF_2340 Bacteria 1TP9J@1239,3F4RT@33958,4HABW@91061,COG0150@1,COG0150@2 NA|NA|NA F Phosphoribosylformylglycinamidine cyclo-ligase GOKNOHPG_01223 1033837.WANG_1545 0.0 1407.5 Lactobacillaceae purH GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.purH Bacteria 1TPQ5@1239,3F4FD@33958,4H9YY@91061,COG0138@1,COG0138@2 NA|NA|NA F Bifunctional purine biosynthesis protein PurH GOKNOHPG_01224 1033837.WANG_1546 8.1e-243 845.9 Lactobacillaceae purD 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS05245,iYO844.BSU06530 Bacteria 1UHN9@1239,3F4Z8@33958,4HA70@91061,COG0151@1,COG0151@2 NA|NA|NA F Belongs to the GARS family GOKNOHPG_01225 1423754.BALY01000005_gene1237 4e-41 173.7 Lactobacillaceae Bacteria 1UI8X@1239,3FBSZ@33958,4ISGE@91061,COG2461@1,COG2461@2 NA|NA|NA S PAS domain GOKNOHPG_01226 272621.LBA1026 2.2e-80 305.1 Lactobacillaceae akr5f 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 1TPM1@1239,3FB4Q@33958,4H9XJ@91061,COG0656@1,COG0656@2 NA|NA|NA S reductase GOKNOHPG_01227 1423754.BALY01000018_gene342 1.2e-23 115.5 Bacilli Bacteria 1U2GS@1239,4H9R9@91061,COG1028@1,COG1028@2 NA|NA|NA IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) GOKNOHPG_01228 405566.lhv_0446 4.6e-46 190.3 Lactobacillaceae Bacteria 1UZVA@1239,3F4KP@33958,4HH09@91061,COG3039@1,COG3039@2 NA|NA|NA L An automated process has identified a potential problem with this gene model GOKNOHPG_01229 1423748.BALB01000031_gene1914 3.3e-102 377.9 Lactobacillaceae Bacteria 1U7B3@1239,29Q0Z@1,30AZG@2,3F992@33958,4IH63@91061 NA|NA|NA GOKNOHPG_01230 1423748.BALB01000031_gene1913 2.7e-94 351.3 Lactobacillaceae Bacteria 1TUPQ@1239,2C0IE@1,2Z7YA@2,3F4HC@33958,4IEVE@91061 NA|NA|NA GOKNOHPG_01231 1423748.BALB01000031_gene1913 1.2e-73 282.7 Lactobacillaceae Bacteria 1TUPQ@1239,2C0IE@1,2Z7YA@2,3F4HC@33958,4IEVE@91061 NA|NA|NA GOKNOHPG_01232 1423748.BALB01000031_gene1913 3e-42 177.6 Lactobacillaceae Bacteria 1TUPQ@1239,2C0IE@1,2Z7YA@2,3F4HC@33958,4IEVE@91061 NA|NA|NA GOKNOHPG_01233 1423748.BALB01000031_gene1912 8.9e-12 75.1 Lactobacillaceae Bacteria 1VQ4B@1239,2A8RI@1,30XU8@2,3F4H8@33958,4IJHJ@91061 NA|NA|NA GOKNOHPG_01234 405566.lhv_1195 3.3e-163 581.3 Lactobacillaceae Bacteria 1VQ4B@1239,2A8RI@1,30XU8@2,3F4H8@33958,4IJHJ@91061 NA|NA|NA GOKNOHPG_01235 405566.lhv_1195 8.1e-117 426.4 Lactobacillaceae Bacteria 1VQ4B@1239,2A8RI@1,30XU8@2,3F4H8@33958,4IJHJ@91061 NA|NA|NA GOKNOHPG_01236 405566.lhv_1196 2.7e-88 331.3 Lactobacillaceae XK27_09675 ko:K07105 ko00000 Bacteria 1UHPQ@1239,3FBT6@33958,4IS5I@91061,COG0454@1,COG0454@2 NA|NA|NA K Acetyltransferase (GNAT) domain GOKNOHPG_01237 326425.lhe_1089 1.3e-51 209.1 Lactobacillaceae Bacteria 1U62T@1239,29P3F@1,30A1N@2,3F6WA@33958,4IFRY@91061 NA|NA|NA S Protein of unknown function (DUF3021) GOKNOHPG_01238 326425.lhe_1090 1.1e-74 285.8 Lactobacillaceae Bacteria 1U5WZ@1239,3F6MT@33958,4IFKG@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain GOKNOHPG_01239 326425.lhe_1091 2.3e-38 164.5 Lactobacillaceae Bacteria 1U75H@1239,29PX4@1,30AVF@2,3F907@33958,4IH06@91061 NA|NA|NA GOKNOHPG_01240 326425.lhe_1092 3e-90 337.8 Lactobacillaceae magIII ko:K07457 ko00000 Bacteria 1V4SG@1239,3F62T@33958,4HI5U@91061,COG2231@1,COG2231@2 NA|NA|NA L Base excision DNA repair protein, HhH-GPD family GOKNOHPG_01241 326425.lhe_1092 8.9e-20 101.7 Lactobacillaceae magIII ko:K07457 ko00000 Bacteria 1V4SG@1239,3F62T@33958,4HI5U@91061,COG2231@1,COG2231@2 NA|NA|NA L Base excision DNA repair protein, HhH-GPD family GOKNOHPG_01242 1423743.JCM14108_347 9.8e-21 105.9 Lactobacillaceae folT Bacteria 1V5I7@1239,3F5GB@33958,4HK9Q@91061,COG4720@1,COG4720@2 NA|NA|NA S ECF transporter, substrate-specific component GOKNOHPG_01243 326425.lhe_1094 8.5e-57 226.1 Lactobacillaceae folB 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01633,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503,R03504,R11037,R11073 RC00002,RC00017,RC00121,RC00721,RC00842,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 1VA0I@1239,3F7N6@33958,4HKKK@91061,COG1539@1,COG1539@2 NA|NA|NA H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin GOKNOHPG_01244 1423743.JCM14108_349 3.9e-201 707.2 Lactobacillaceae folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 1.13.11.81,2.5.1.15,2.7.6.3,3.5.4.16,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01495,ko:K01633,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841,M00842,M00843 R00428,R03066,R03067,R03503,R03504,R04639,R05046,R05048,R11037,R11073 RC00002,RC00017,RC00121,RC00263,RC00294,RC00323,RC00721,RC00842,RC00943,RC00945,RC01188,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv3609c Bacteria 1TRNM@1239,3F4A0@33958,4HAXS@91061,COG0302@1,COG0302@2,COG0801@1,COG0801@2 NA|NA|NA F GTP cyclohydrolase 1 GOKNOHPG_01245 353496.LBU_0194 9.9e-247 859.0 Lactobacillaceae folC 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0166 Bacteria 1TPX5@1239,3F3ZR@33958,4HBJM@91061,COG0285@1,COG0285@2 NA|NA|NA H Belongs to the folylpolyglutamate synthase family GOKNOHPG_01246 405566.lhv_1204 1.3e-199 702.2 Lactobacillaceae folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796,ko:K18824,ko:K18974 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1TPKT@1239,3F4SS@33958,4H9SY@91061,COG0294@1,COG0294@2 NA|NA|NA H dihydropteroate synthase GOKNOHPG_01247 1423743.JCM14108_352 4e-98 364.0 Lactobacillaceae 3.6.1.55,3.6.1.67 ko:K03207,ko:K03574,ko:K19965 ko00790,map00790 M00126 R04638 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1VFNI@1239,3F4CG@33958,4HQPJ@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain GOKNOHPG_01248 1423743.JCM14108_353 1.9e-23 114.4 Lactobacillaceae hutG 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6B3@1239,3F6V6@33958,4HQ4E@91061,COG3741@1,COG3741@2 NA|NA|NA E N-formylglutamate amidohydrolase GOKNOHPG_01249 1033837.WANG_1275 3e-57 227.6 Lactobacillaceae adhR Bacteria 1VAAP@1239,3F6JI@33958,4HKZ9@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance GOKNOHPG_01250 1033837.WANG_1274 2.5e-110 404.8 Lactobacillaceae papP ko:K02029 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TRU3@1239,3F3XD@33958,4HGE1@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter, permease protein GOKNOHPG_01251 1033837.WANG_1273 2e-86 325.5 Lactobacillaceae ko:K02029,ko:K10040 ko02010,map02010 M00228,M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3 Bacteria 1TR7R@1239,3F45E@33958,4HGVA@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease GOKNOHPG_01252 1033837.WANG_1272 1.6e-134 485.3 Lactobacillaceae glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,3FC3P@33958,4HDK7@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein GOKNOHPG_01253 326425.lhe_1105 9.1e-161 572.8 Lactobacillaceae cjaA ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TT11@1239,3F54P@33958,4HFBQ@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter substrate-binding protein GOKNOHPG_01254 1423754.BALY01000062_gene1837 6.8e-157 560.1 Lactobacillaceae ko:K07484 ko00000 Bacteria 1TQST@1239,3F47D@33958,4HPQC@91061,COG4974@1,COG4974@2 NA|NA|NA L Transposase IS66 family GOKNOHPG_01255 1423754.BALY01000019_gene735 2.5e-86 325.1 Lactobacillaceae lepB 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1V7H9@1239,3F56W@33958,4HMGQ@91061,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family GOKNOHPG_01256 405566.lhv_0620 3e-96 357.8 Lactobacillaceae Bacteria 1UZVA@1239,3F4KP@33958,4HH09@91061,COG3039@1,COG3039@2 NA|NA|NA L An automated process has identified a potential problem with this gene model GOKNOHPG_01257 525365.HMPREF0548_0243 3e-110 405.2 Lactobacillaceae mrr GO:0001101,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009295,GO:0009415,GO:0009628,GO:0009987,GO:0010035,GO:0015666,GO:0016787,GO:0016788,GO:0032067,GO:0034641,GO:0042221,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051599,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901700 ko:K07448 ko00000,ko02048 Bacteria 1V1TA@1239,3F5UV@33958,4HC3T@91061,COG1715@1,COG1715@2 NA|NA|NA L restriction endonuclease GOKNOHPG_01258 203120.LEUM_1980 1.4e-31 142.1 Leuconostocaceae Bacteria 1VZDZ@1239,2DY5Q@1,34896@2,4AY9W@81850,4HZ9A@91061 NA|NA|NA GOKNOHPG_01259 543734.LCABL_21480 6.8e-127 459.9 Lactobacillaceae tnp ko:K07498 ko00000 Bacteria 1TTKR@1239,3F4NE@33958,4HCB4@91061,COG3316@1,COG3316@2 NA|NA|NA L DDE domain GOKNOHPG_01260 1423814.HMPREF0549_1573 2.7e-54 219.5 Bacilli Bacteria 1VAIE@1239,4HZG7@91061,COG4127@1,COG4127@2 NA|NA|NA S FRG GOKNOHPG_01261 148814.JI66_00050 2.1e-227 794.7 Lactobacillaceae tnp ko:K07493 ko00000 Bacteria 1TP4C@1239,3FB4C@33958,4HB0P@91061,COG3328@1,COG3328@2 NA|NA|NA L MULE transposase domain GOKNOHPG_01263 568703.LGG_02395 8e-135 486.5 Lactobacillaceae ko:K07052 ko00000 Bacteria 1W74D@1239,3F80E@33958,4HXYG@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity GOKNOHPG_01264 568703.LGG_02397 3.9e-67 260.8 Lactobacillaceae Bacteria 1VG8M@1239,3F6QY@33958,4HYHM@91061,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator GOKNOHPG_01265 568703.LGG_02398 2.9e-252 877.5 Lactobacillaceae Bacteria 1UHNW@1239,3FCCP@33958,4IS4S@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Major Facilitator Superfamily GOKNOHPG_01266 543734.LCABL_21480 6.8e-127 459.9 Lactobacillaceae tnp ko:K07498 ko00000 Bacteria 1TTKR@1239,3F4NE@33958,4HCB4@91061,COG3316@1,COG3316@2 NA|NA|NA L DDE domain GOKNOHPG_01267 416870.llmg_0676 3.6e-82 310.8 Bacteria yitI Bacteria COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase GOKNOHPG_01268 1033837.WANG_1745 5.6e-92 344.0 Bacilli 3.4.13.21 ko:K05995 ko00000,ko01000,ko01002 Bacteria 1TTAT@1239,4HD0E@91061,COG3340@1,COG3340@2 NA|NA|NA E Belongs to the peptidase S51 family GOKNOHPG_01269 1214184.ALKY01000026_gene1653 2.6e-16 92.0 Streptococcus suis XK27_05370 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 Bacteria 1V436@1239,1WT46@1307,4I3QW@91061,COG0135@1,COG0135@2 NA|NA|NA E phosphoribosylanthranilate isomerase activity GOKNOHPG_01270 904293.HMPREF9176_0969 5.5e-43 181.0 Bacilli Bacteria 1W1AX@1239,4HY0T@91061,COG1476@1,COG1476@2 NA|NA|NA K Cro/C1-type HTH DNA-binding domain GOKNOHPG_01271 1045854.WKK_06857 7.1e-207 726.5 Leuconostocaceae recN ko:K03631,ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000,ko03400 3.A.1.112,8.A.1 Bacteria 1UI5C@1239,4AWZS@81850,4ISE9@91061,COG0497@1,COG0497@2 NA|NA|NA L Plasmid recombination enzyme GOKNOHPG_01272 1045854.WKK_06862 6e-184 650.2 Leuconostocaceae ko:K07498 ko00000 Bacteria 1V1XJ@1239,4AXJP@81850,4HD1W@91061,COG5527@1,COG5527@2 NA|NA|NA L Initiator Replication protein GOKNOHPG_01273 1138822.PL11_10425 5e-61 240.7 Lactobacillaceae Bacteria 1V4IG@1239,2A9SW@1,30Z0H@2,3F884@33958,4HHW5@91061 NA|NA|NA GOKNOHPG_01274 1408473.JHXO01000001_gene1973 3.3e-48 198.7 Bacteria Bacteria COG4916@1,COG4916@2 NA|NA|NA S TIR domain GOKNOHPG_01275 349519.LCK_00758 1.4e-170 605.5 Leuconostocaceae Bacteria 1TRSF@1239,4AXKQ@81850,4HVB3@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives IS30 family GOKNOHPG_01277 1423758.BN55_05390 7.6e-67 260.8 Lactobacillaceae ropB Bacteria 1VD8E@1239,3F61C@33958,4HMD2@91061,COG1396@1,COG1396@2 NA|NA|NA K Transcriptional regulator GOKNOHPG_01278 1423815.BACR01000056_gene2365 3e-15 86.7 Lactobacillaceae Bacteria 1U5AH@1239,2DVX3@1,33XIG@2,3F5D0@33958,4IF1T@91061 NA|NA|NA S Plasmid replication protein GOKNOHPG_01279 326425.lhe_0344 6.9e-213 746.5 Lactobacillaceae ko:K02445 ko00000,ko02000 2.A.1.4.3 Bacteria 1TS33@1239,3F4E6@33958,4HBVJ@91061,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily GOKNOHPG_01281 585524.HMPREF0493_1651 0.0 1538.5 Lactobacillaceae res 3.1.21.5 ko:K01156 ko00000,ko01000,ko02048 Bacteria 1TPRR@1239,3F4QK@33958,4HBNH@91061,COG3587@1,COG3587@2 NA|NA|NA L Type III restriction enzyme, res subunit GOKNOHPG_01282 585524.HMPREF0493_1652 1.6e-218 765.8 Lactobacillaceae mod 2.1.1.72 ko:K07316 ko00000,ko01000,ko02048 Bacteria 1TR8A@1239,3F504@33958,4HBP1@91061,COG2189@1,COG2189@2 NA|NA|NA L DNA methylase GOKNOHPG_01283 797515.HMPREF9103_01291 5.7e-172 610.1 Lactobacillaceae hprA 1.1.1.29 ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCX@1239,3F4Z6@33958,4HASY@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family GOKNOHPG_01284 1133569.AHYZ01000017_gene1019 6.8e-97 360.1 Lactobacillaceae Bacteria 1TQN4@1239,3F5I0@33958,4HKTX@91061,COG4227@1,COG4227@2 NA|NA|NA L Psort location Cytoplasmic, score GOKNOHPG_01285 908339.HMPREF9265_0261 4e-90 337.4 Lactobacillaceae Bacteria 1TQN4@1239,3FC8F@33958,4HN8F@91061,COG4227@1,COG4227@2 NA|NA|NA L Psort location Cytoplasmic, score GOKNOHPG_01286 913848.AELK01000077_gene1657 1.7e-18 98.2 Lactobacillaceae Bacteria 1U69B@1239,29P8A@1,30A6D@2,3F7CJ@33958,4IG0G@91061 NA|NA|NA GOKNOHPG_01287 220668.45723572 0.0 1154.4 Lactobacillaceae traI 5.99.1.2 ko:K03169 ko00000,ko01000,ko03032 Bacteria 1TPJD@1239,3F4W6@33958,4HAZV@91061,COG0550@1,COG0550@2 NA|NA|NA L This gene contains a nucleotide ambiguity which may be the result of a sequencing error GOKNOHPG_01288 1423816.BACQ01000038_gene1588 6.4e-67 260.0 Lactobacillaceae Bacteria 1U5SV@1239,29NXD@1,309VH@2,3F6FI@33958,4IFGT@91061 NA|NA|NA GOKNOHPG_01289 908339.HMPREF9265_1417 3.3e-147 527.7 Lactobacillaceae Bacteria 1VPIB@1239,2EN0Y@1,33FP4@2,3F4ME@33958,4HRWI@91061 NA|NA|NA GOKNOHPG_01290 1138822.PL11_10215 7.5e-62 243.0 Lactobacillaceae Bacteria 1UQAF@1239,2BAF6@1,323VN@2,3F6F2@33958,4IFGF@91061 NA|NA|NA GOKNOHPG_01291 908339.HMPREF9265_1755 6.7e-263 912.9 Lactobacillaceae traK ko:K03205 ko03070,map03070 M00333 ko00000,ko00001,ko00002,ko02044 3.A.7 Bacteria 1TPCF@1239,3F4S3@33958,4H9ZN@91061,COG3505@1,COG3505@2 NA|NA|NA U TraM recognition site of TraD and TraG GOKNOHPG_01293 220668.45723577 1.9e-67 261.9 Lactobacillaceae Bacteria 1U59I@1239,2AC4N@1,311NX@2,3F59S@33958,4IF0X@91061 NA|NA|NA GOKNOHPG_01294 797515.HMPREF9103_01697 1.5e-57 228.8 Lactobacillaceae Bacteria 1U5XH@1239,3F6NC@33958,4IFKV@91061,COG0526@1,COG0526@2 NA|NA|NA CO COG0526, thiol-disulfide isomerase and thioredoxins GOKNOHPG_01295 908339.HMPREF9265_1758 1.5e-88 332.4 Lactobacillaceae Bacteria 1UFKJ@1239,29UXR@1,30GAH@2,3F46S@33958,4IEU2@91061 NA|NA|NA GOKNOHPG_01296 1045004.OKIT_0530 3.4e-203 714.1 Bacilli ko:K03199 ko03070,map03070 M00333 ko00000,ko00001,ko00002,ko02044 3.A.7 Bacteria 1VW67@1239,4HWSY@91061,COG0741@1,COG0741@2,COG0791@1,COG0791@2 NA|NA|NA M CHAP domain GOKNOHPG_01297 1045004.OKIT_0529 5.1e-217 760.4 Bacilli polC 2.4.1.129,2.7.7.7,3.4.16.4 ko:K03763,ko:K05366 ko00230,ko00240,ko00550,ko01100,ko01501,ko03030,ko03430,ko03440,map00230,map00240,map00550,map01100,map01501,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko01003,ko01011,ko03032,ko03400 GT51 Bacteria 1V1PS@1239,4HGKF@91061,COG4499@1,COG4499@2 NA|NA|NA S WXG100 protein secretion system (Wss), protein YukC GOKNOHPG_01298 1291743.LOSG293_220160 0.0 1300.8 Lactobacillaceae traE Bacteria 1TS2J@1239,3F3NC@33958,4HYWU@91061,COG3451@1,COG3451@2 NA|NA|NA U type IV secretory pathway VirB4 GOKNOHPG_01299 1045004.OKIT_0527 9.6e-118 429.5 Bacilli Bacteria 1VEP6@1239,2ECAZ@1,3369B@2,4HQSU@91061 NA|NA|NA GOKNOHPG_01300 908339.HMPREF9265_1763 1.5e-35 155.6 Lactobacillaceae Bacteria 1VVYR@1239,2F48Y@1,33WZQ@2,3F6NH@33958,4HW55@91061 NA|NA|NA GOKNOHPG_01301 1138822.PL11_10165 4.3e-50 203.8 Lactobacillaceae Bacteria 1U5UW@1239,2BZG5@1,309WK@2,3F6IN@33958,4IFIG@91061 NA|NA|NA S Cag pathogenicity island, type IV secretory system GOKNOHPG_01302 1400520.LFAB_17250 7.6e-101 373.2 Lactobacillaceae Bacteria 1U59R@1239,29NNG@1,309KE@2,3F5AZ@33958,4IF1A@91061 NA|NA|NA GOKNOHPG_01303 1138822.PL11_10155 2.1e-33 148.3 Lactobacillaceae Bacteria 1U6EB@1239,29PC9@1,30AAH@2,3F7QB@33958,4IG63@91061 NA|NA|NA GOKNOHPG_01304 1400520.LFAB_17260 0.0 1276.9 Lactobacillaceae Bacteria 1VQWC@1239,3F4DP@33958,4HD6B@91061,COG0507@1,COG0507@2 NA|NA|NA L MobA MobL family protein GOKNOHPG_01305 1423734.JCM14202_2802 2.6e-09 66.6 Lactobacillaceae Bacteria 1U69C@1239,29P8B@1,30A6E@2,3F7CM@33958,4IG0H@91061 NA|NA|NA GOKNOHPG_01306 1033837.WANG_1719 3.2e-38 164.1 Lactobacillaceae Bacteria 1VKZC@1239,2EJES@1,33D5R@2,3F6Y2@33958,4HRGI@91061 NA|NA|NA GOKNOHPG_01307 944562.HMPREF9102_2160 1.2e-76 292.7 Lactobacillaceae Bacteria 1V3AX@1239,3F4YX@33958,4HVK3@91061,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family GOKNOHPG_01308 908339.HMPREF9265_1393 3.9e-22 110.2 Lactobacillaceae Bacteria 1V3AX@1239,3F4YX@33958,4HVK3@91061,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family GOKNOHPG_01309 1138822.PL11_10075 3.2e-158 564.7 Bacilli repA Bacteria 1TQXM@1239,2DBC6@1,2Z8BZ@2,4IQUN@91061 NA|NA|NA S Replication initiator protein A (RepA) N-terminus GOKNOHPG_01310 1400520.LFAB_17480 3e-32 144.1 Lactobacillaceae Bacteria 1U665@1239,29P62@1,30A47@2,3F75R@33958,4IFW4@91061 NA|NA|NA GOKNOHPG_01311 1400520.LFAB_17485 8.9e-142 509.6 Lactobacillaceae ko:K03496 ko00000,ko03036,ko04812 Bacteria 1V6Q6@1239,3F477@33958,4HINH@91061,COG1192@1,COG1192@2 NA|NA|NA D CobQ CobB MinD ParA nucleotide binding domain protein GOKNOHPG_01312 203123.OEOE_0334 1.5e-55 221.9 Leuconostocaceae tnp2PF3 Bacteria 1VW4T@1239,4AYJV@81850,4HWBF@91061,COG3293@1,COG3293@2 NA|NA|NA L Putative transposase of IS4/5 family (DUF4096) GOKNOHPG_01313 1033837.WANG_1733 3.1e-78 297.7 Lactobacillaceae tnp2PF3 Bacteria 1VTEC@1239,3F62D@33958,4HUXQ@91061,COG3293@1,COG3293@2 NA|NA|NA L Transposase DDE domain GOKNOHPG_01315 1158604.I591_02054 1.2e-54 220.3 Enterococcaceae ysnF ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1V9A1@1239,4AZ6W@81852,4HISC@91061,COG3861@1,COG3861@2 NA|NA|NA S Heat induced stress protein YflT GOKNOHPG_01316 1246.JMEA01000018_gene772 1e-29 135.6 Leuconostocaceae ko:K07483 ko00000 Bacteria 1VWXF@1239,4AXXS@81850,4HWX3@91061,COG2963@1,COG2963@2 NA|NA|NA L Transposase GOKNOHPG_01317 1229517.AMFD01000006_gene1781 1.4e-49 202.6 Lactococcus ko:K04763 ko00000,ko03036 Bacteria 1UD2A@1239,1YC8P@1357,4IEJF@91061,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase family GOKNOHPG_01318 1423743.JCM14108_3252 1.7e-61 241.9 Lactobacillaceae Bacteria 1VQDB@1239,2EHZR@1,33BR8@2,3F5IT@33958,4HRJT@91061 NA|NA|NA GOKNOHPG_01319 1045004.OKIT_0519 1.1e-43 182.2 Bacilli relB ko:K07473 ko00000,ko02048 Bacteria 1VGJW@1239,4HR7A@91061,COG3077@1,COG3077@2 NA|NA|NA L Addiction module antitoxin, RelB DinJ family GOKNOHPG_01320 1423780.LOT_2226 7.9e-165 586.6 Lactobacillaceae repA Bacteria 1VHQA@1239,2DP1C@1,3304N@2,3F55E@33958,4HPY6@91061 NA|NA|NA S Replication initiator protein A GOKNOHPG_01321 1423780.LOT_2227 6.6e-142 510.0 Lactobacillaceae soj ko:K03496 ko00000,ko03036,ko04812 Bacteria 1TP8S@1239,3FB46@33958,4HAYM@91061,COG1192@1,COG1192@2 NA|NA|NA D AAA domain GOKNOHPG_01322 1423780.LOT_2228 4.6e-29 133.3 Lactobacillaceae Bacteria 1U71N@1239,29PU7@1,30ASC@2,3F8V3@33958,4IGW4@91061 NA|NA|NA GOKNOHPG_01323 1122149.BACN01000113_gene2019 6.1e-83 313.9 Lactobacillaceae Bacteria 1TQ93@1239,3F4RD@33958,4HDNZ@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein GOKNOHPG_01324 220668.lp_3573 3.5e-69 267.3 Lactobacillaceae Bacteria 1V717@1239,2AK1X@1,31ARI@2,3F6WW@33958,4HIQ9@91061 NA|NA|NA S Pyrimidine dimer DNA glycosylase GOKNOHPG_01325 1045004.OKIT_0545 5.5e-39 166.8 Bacilli tnpR Bacteria 1UZM8@1239,4IQ67@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain GOKNOHPG_01327 768486.EHR_07355 3.3e-10 72.0 Firmicutes Bacteria 1W4RT@1239,2DD5H@1,2ZGM4@2 NA|NA|NA GOKNOHPG_01328 405566.lhv_1909 2.6e-107 395.2 Lactobacillaceae ropB Bacteria 1VD8E@1239,3F61C@33958,4HMD2@91061,COG1396@1,COG1396@2 NA|NA|NA K Transcriptional regulator GOKNOHPG_01329 326425.lhe_1562 4.4e-31 140.2 Lactobacillaceae Bacteria 1U8JH@1239,29QS7@1,30BS2@2,3FB1X@33958,4IIHG@91061 NA|NA|NA GOKNOHPG_01330 326425.lhe_1563 2.9e-36 157.5 Lactobacillaceae Bacteria 1W6M0@1239,2ETIJ@1,33M2D@2,3F79G@33958,4IFY8@91061 NA|NA|NA GOKNOHPG_01331 405566.lhv_1697 6e-91 340.1 Lactobacillaceae 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1V55F@1239,3F50F@33958,4HJEI@91061,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain GOKNOHPG_01332 405566.lhv_1698 1e-170 605.9 Lactobacillaceae fba 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ01@1239,3F4EF@33958,4H9ZU@91061,COG0191@1,COG0191@2 NA|NA|NA G Fructose-1,6-bisphosphate aldolase, class II GOKNOHPG_01333 326425.lhe_1566 0.0 1121.3 Lactobacillaceae argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPEZ@1239,3F4DE@33958,4HAR3@91061,COG0018@1,COG0018@2 NA|NA|NA J Arginyl-tRNA synthetase GOKNOHPG_01334 1423748.BALB01000005_gene673 2.1e-12 78.2 Lactobacillaceae 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1A7@1239,3F655@33958,4HG0B@91061,COG5464@1,COG5464@2 NA|NA|NA S PD-(D/E)XK nuclease family transposase GOKNOHPG_01335 326425.lhe_1567 2.5e-112 411.4 Lactobacillaceae 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1A7@1239,3F655@33958,4HG0B@91061,COG5464@1,COG5464@2 NA|NA|NA S PD-(D/E)XK nuclease family transposase GOKNOHPG_01336 525365.HMPREF0548_0408 1.2e-21 108.2 Lactobacillaceae padC ko:K13727 ko00000,ko01000 Bacteria 1UY0X@1239,3F4P4@33958,4HAN3@91061,COG3479@1,COG3479@2 NA|NA|NA Q Phenolic acid decarboxylase GOKNOHPG_01337 326425.lhe_1568 7.6e-32 142.5 Lactobacillaceae padC ko:K13727 ko00000,ko01000 Bacteria 1UY0X@1239,3F4P4@33958,4HAN3@91061,COG3479@1,COG3479@2 NA|NA|NA Q Phenolic acid decarboxylase GOKNOHPG_01338 405566.lhv_1703 1.1e-87 329.3 Lactobacillaceae padR Bacteria 1V5J2@1239,3FBD5@33958,4IPMM@91061,COG1695@1,COG1695@2 NA|NA|NA K Virulence activator alpha C-term GOKNOHPG_01339 326425.lhe_1570 5.7e-110 403.7 Lactobacillaceae Bacteria 1V4KP@1239,3F6PH@33958,4HIBF@91061,COG1376@1,COG1376@2 NA|NA|NA M ErfK YbiS YcfS YnhG GOKNOHPG_01340 326425.lhe_1571 1.1e-153 549.3 Lactobacillaceae nnrD 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 1TNZE@1239,3F480@33958,4HBZC@91061,COG0063@1,COG0063@2 NA|NA|NA H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration GOKNOHPG_01341 326425.lhe_1572 1.2e-241 842.0 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1TQN0@1239,3F43S@33958,4HBD4@91061,COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family GOKNOHPG_01343 405566.lhv_1707 7e-47 193.0 Lactobacillaceae pspC ko:K03973 ko00000,ko02048,ko03000 Bacteria 1VKBQ@1239,3F87Y@33958,4HRGW@91061,COG1983@1,COG1983@2 NA|NA|NA KT PspC domain GOKNOHPG_01344 405566.lhv_1708 1.6e-37 162.2 Lactobacillaceae psd 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR34@1239,3F5QB@33958,4HB6I@91061,COG0688@1,COG0688@2 NA|NA|NA I Belongs to the phosphatidylserine decarboxylase family GOKNOHPG_01345 1423748.BALB01000005_gene659 7.2e-37 159.5 Lactobacillaceae Bacteria 1U6CG@1239,2DKPU@1,30A92@2,3F7KQ@33958,4IG45@91061 NA|NA|NA S Enterocin A Immunity GOKNOHPG_01346 1423748.BALB01000005_gene658 1.3e-137 495.7 Lactobacillaceae yxeH Bacteria 1TR16@1239,3F55S@33958,4HCZ6@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase GOKNOHPG_01347 1033837.WANG_1181 4.3e-18 96.7 Lactobacillaceae 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1A7@1239,3F655@33958,4HG0B@91061,COG5464@1,COG5464@2 NA|NA|NA S PD-(D/E)XK nuclease family transposase GOKNOHPG_01348 1423748.BALB01000005_gene656 6.3e-16 89.7 Lactobacillaceae frnE Bacteria 1TZ1N@1239,3F5IF@33958,4HEBF@91061,COG2761@1,COG2761@2 NA|NA|NA Q DSBA-like thioredoxin domain GOKNOHPG_01349 1423748.BALB01000005_gene656 3.2e-15 87.0 Lactobacillaceae frnE Bacteria 1TZ1N@1239,3F5IF@33958,4HEBF@91061,COG2761@1,COG2761@2 NA|NA|NA Q DSBA-like thioredoxin domain GOKNOHPG_01350 1423748.BALB01000005_gene656 2.3e-37 161.0 Lactobacillaceae frnE Bacteria 1TZ1N@1239,3F5IF@33958,4HEBF@91061,COG2761@1,COG2761@2 NA|NA|NA Q DSBA-like thioredoxin domain GOKNOHPG_01351 326425.lhe_1578 3.5e-174 617.5 Lactobacillaceae trxB 1.8.1.9 ko:K00384 ko00450,map00450 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 Bacteria 1TNZS@1239,3F411@33958,4HA4N@91061,COG0492@1,COG0492@2 NA|NA|NA C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family GOKNOHPG_01352 405566.lhv_1714 4.4e-115 420.6 Lactobacillaceae M1-798 ko:K03892 ko00000,ko03000 Bacteria 1V2NW@1239,3F6DW@33958,4HGAA@91061,COG0607@1,COG0607@2,COG0640@1,COG0640@2 NA|NA|NA K Rhodanese Homology Domain GOKNOHPG_01353 405566.lhv_1715 1.4e-59 235.3 Lactobacillaceae ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1U6PP@1239,3F89E@33958,4IGGN@91061,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin GOKNOHPG_01354 326425.lhe_1581 1.1e-19 101.7 Lactobacillaceae Bacteria 1U892@1239,29QKD@1,30BK1@2,3FAQ3@33958,4II6X@91061 NA|NA|NA GOKNOHPG_01355 1423748.BALB01000005_gene651 1.7e-22 113.2 Lactobacillaceae Bacteria 1VSP5@1239,3F4FY@33958,4HUK1@91061,COG3266@1,COG3266@2 NA|NA|NA UW LPXTG-motif cell wall anchor domain protein GOKNOHPG_01356 349123.Lreu23DRAFT_4946 1.7e-15 88.6 Lactobacillaceae infB ko:K02519,ko:K03832 ko00000,ko02000,ko03012,ko03029 2.C.1.1 Bacteria 1VSP5@1239,3F4FY@33958,4HUK1@91061,COG0810@1,COG0810@2,COG3266@1,COG3266@2,COG4932@1,COG4932@2 NA|NA|NA UW LPXTG-motif cell wall anchor domain protein GOKNOHPG_01357 324831.LGAS_0045 2.5e-71 276.2 Lactobacillaceae infB ko:K02519,ko:K03832 ko00000,ko02000,ko03012,ko03029 2.C.1.1 Bacteria 1VSP5@1239,3F4FY@33958,4HUK1@91061,COG0810@1,COG0810@2,COG3266@1,COG3266@2,COG4932@1,COG4932@2 NA|NA|NA UW LPXTG-motif cell wall anchor domain protein GOKNOHPG_01358 46256.BBIK01000007_gene1282 3.1e-84 317.8 Bacilli yhbO GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0006139,GO:0006259,GO:0006281,GO:0006464,GO:0006517,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009100,GO:0009266,GO:0009268,GO:0009314,GO:0009408,GO:0009411,GO:0009416,GO:0009438,GO:0009628,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019249,GO:0019538,GO:0019752,GO:0030091,GO:0032787,GO:0033554,GO:0034641,GO:0036211,GO:0036524,GO:0036525,GO:0042180,GO:0042182,GO:0042802,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0046394,GO:0046483,GO:0050896,GO:0051596,GO:0051716,GO:0061727,GO:0071704,GO:0072330,GO:0090304,GO:0140096,GO:1901135,GO:1901360,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901617 3.5.1.124 ko:K05520 ko00000,ko01000,ko01002 Bacteria 1V3I7@1239,4HFNG@91061,COG0693@1,COG0693@2 NA|NA|NA S Intracellular protease GOKNOHPG_01360 1074451.CRL705_1859 0.0 1523.5 Lactobacillaceae uvrA2 Bacteria 1TR1H@1239,3F50Y@33958,4H9RE@91061,COG0178@1,COG0178@2 NA|NA|NA L ABC transporter GOKNOHPG_01361 1423807.BACO01000087_gene2502 3.3e-16 90.9 Lactobacillaceae Bacteria 1UZM8@1239,3FBG8@33958,4IQ67@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain GOKNOHPG_01362 797515.HMPREF9103_00814 3e-75 287.7 Lactobacillaceae hsp1 ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 1VG0E@1239,3F7DR@33958,4HPDH@91061,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family GOKNOHPG_01363 797515.HMPREF9103_00813 4.3e-71 273.9 Lactobacillaceae hsp1 ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 1VG0E@1239,3F7DR@33958,4HPDH@91061,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family GOKNOHPG_01364 797515.HMPREF9103_00812 2e-32 144.8 Lactobacillaceae Bacteria 1U67Q@1239,29P74@1,30A57@2,3F79H@33958,4IFY9@91061 NA|NA|NA GOKNOHPG_01365 797515.HMPREF9103_00811 1.6e-100 372.1 Lactobacillaceae Bacteria 1UYIP@1239,3FC4J@33958,4HJ4M@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family GOKNOHPG_01366 797515.HMPREF9103_00809 0.0 1130.5 Lactobacillaceae lai 4.2.1.53 ko:K10254 ko00000,ko01000 Bacteria 1TQZ6@1239,3F3QX@33958,4HAYH@91061,COG4716@1,COG4716@2 NA|NA|NA S Myosin-crossreactive antigen GOKNOHPG_01367 525309.HMPREF0494_0054 7.9e-40 169.5 Lactobacillaceae Bacteria 1TQAX@1239,3F429@33958,4HCFF@91061,COG1961@1,COG1961@2 NA|NA|NA L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed GOKNOHPG_01368 1291743.LOSG293_220340 1.7e-148 531.9 Lactobacillaceae ko:K03496 ko00000,ko03036,ko04812 Bacteria 1V6Q6@1239,3F477@33958,4HINH@91061,COG1192@1,COG1192@2 NA|NA|NA D CobQ CobB MinD ParA nucleotide binding domain protein GOKNOHPG_01369 1291743.LOSG293_220350 2.9e-35 154.1 Lactobacillaceae Bacteria 1U68J@1239,29P7R@1,30A5U@2,3F7B0@33958,4IFZF@91061 NA|NA|NA GOKNOHPG_01370 1291743.LOSG293_220360 1.2e-165 589.3 Lactobacillaceae repA Bacteria 1VHQA@1239,2DP1C@1,3304N@2,3F55E@33958,4HPY6@91061 NA|NA|NA S Replication initiator protein A GOKNOHPG_01371 1045004.OKIT_0519 3.9e-44 183.7 Bacilli relB ko:K07473 ko00000,ko02048 Bacteria 1VGJW@1239,4HR7A@91061,COG3077@1,COG3077@2 NA|NA|NA L Addiction module antitoxin, RelB DinJ family GOKNOHPG_01372 1423780.LOT_2224 2.9e-82 311.2 Lactobacillaceae Bacteria 1VQDB@1239,2EHZR@1,33BR8@2,3F5IT@33958,4HRJT@91061 NA|NA|NA GOKNOHPG_01373 1033837.WANG_1719 7.5e-40 169.5 Lactobacillaceae Bacteria 1VKZC@1239,2EJES@1,33D5R@2,3F6Y2@33958,4HRGI@91061 NA|NA|NA GOKNOHPG_01374 908339.HMPREF9265_1193 1.7e-23 114.8 Lactobacillaceae Bacteria 1U69C@1239,29P8B@1,30A6E@2,3F7CM@33958,4IG0H@91061 NA|NA|NA GOKNOHPG_01375 1045004.OKIT_0523 6.2e-152 543.5 Leuconostocaceae traA Bacteria 1VQWC@1239,4AYTM@81850,4HD6B@91061,COG0507@1,COG0507@2 NA|NA|NA L MobA/MobL family GOKNOHPG_01376 334390.LAF_0706 1.3e-70 272.3 Lactobacillaceae tnp ko:K07498 ko00000 Bacteria 1TTKR@1239,3F4NE@33958,4HCB4@91061,COG3316@1,COG3316@2 NA|NA|NA L DDE domain GOKNOHPG_01377 334390.LAF_0706 3.4e-31 140.6 Lactobacillaceae tnp ko:K07498 ko00000 Bacteria 1TTKR@1239,3F4NE@33958,4HCB4@91061,COG3316@1,COG3316@2 NA|NA|NA L DDE domain GOKNOHPG_01378 1136177.KCA1_1180 5.3e-243 846.7 Lactobacillaceae dinF Bacteria 1TNZN@1239,3FC3X@33958,4HANM@91061,COG0534@1,COG0534@2 NA|NA|NA V MatE GOKNOHPG_01380 326425.lhe_1166 6.2e-120 436.8 Lactobacillaceae Bacteria 1UG47@1239,29NT4@1,30GID@2,3F5H9@33958,4IF33@91061 NA|NA|NA GOKNOHPG_01382 326425.lhe_1167 1.1e-145 522.7 Lactobacillaceae Bacteria 1U5IX@1239,29NT4@1,309R6@2,3F624@33958,4HZ1H@91061 NA|NA|NA GOKNOHPG_01383 326425.lhe_1168 4e-122 444.1 Lactobacillaceae skfE ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPUP@1239,3F4GA@33958,4HG6U@91061,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities GOKNOHPG_01384 326425.lhe_1169 1.1e-50 205.7 Lactobacillaceae yvoA_1 ko:K07979 ko00000,ko03000 Bacteria 1VA2B@1239,3F6GC@33958,4HPK4@91061,COG1725@1,COG1725@2 NA|NA|NA K Transcriptional regulator, GntR family GOKNOHPG_01385 405566.lhv_1291 8.3e-240 835.9 Lactobacillaceae pepT GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0034701,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045148,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.4 ko:K01258 ko00000,ko01000,ko01002 Bacteria 1TP3A@1239,3F45V@33958,4HAZE@91061,COG2195@1,COG2195@2 NA|NA|NA E Cleaves the N-terminal amino acid of tripeptides GOKNOHPG_01386 326425.lhe_1171 1e-153 549.3 Lactobacillaceae yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.16 ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ27@1239,3F3ZD@33958,4H9NY@91061,COG0327@1,COG0327@2 NA|NA|NA S Belongs to the GTP cyclohydrolase I type 2 NIF3 family GOKNOHPG_01387 405566.lhv_1293 9.3e-124 449.5 Lactobacillaceae trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 ko00000,ko01000,ko03016 Bacteria 1V3I4@1239,3F4GT@33958,4HHIM@91061,COG2384@1,COG2384@2 NA|NA|NA S SAM-dependent methyltransferase GOKNOHPG_01388 272621.LBA1193 3.6e-68 264.2 Lactobacillaceae mutT 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1V6PF@1239,3F66W@33958,4HKTF@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain GOKNOHPG_01389 326425.lhe_1174 6.4e-122 443.4 Lactobacillaceae Bacteria 1UI90@1239,2DVJ8@1,33W59@2,3F3K4@33958,4HD3X@91061 NA|NA|NA S Peptidase family M23 GOKNOHPG_01390 748671.LCRIS_01196 1.2e-197 695.7 Lactobacillaceae sigA GO:0000988,GO:0000990,GO:0001098,GO:0001101,GO:0001108,GO:0001666,GO:0002791,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032879,GO:0032880,GO:0036293,GO:0040007,GO:0042221,GO:0043175,GO:0043254,GO:0044087,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051173,GO:0051223,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070063,GO:0070201,GO:0070482,GO:0071944,GO:0080090,GO:0090087,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:1903530,GO:2000112,GO:2000142,GO:2001141 ko:K03086,ko:K03087 ko02026,ko05111,map02026,map05111 ko00000,ko00001,ko03021 Bacteria 1TPD6@1239,3F4CF@33958,4HB1H@91061,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth GOKNOHPG_01391 326425.lhe_1176 0.0 1209.9 Lactobacillaceae dnaG ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1TQ0X@1239,3F3N1@33958,4HAG2@91061,COG0358@1,COG0358@2 NA|NA|NA L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication GOKNOHPG_01392 326425.lhe_1177 0.0 1329.7 Lactobacillaceae glyS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01879,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iJN678.glyS,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,ic_1306.c4378 Bacteria 1TNZ7@1239,3F4G8@33958,4H9NT@91061,COG0751@1,COG0751@2 NA|NA|NA J Glycyl-tRNA synthetase beta subunit GOKNOHPG_01393 326425.lhe_1178 3.9e-178 630.6 Lactobacillaceae glyQ GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016875,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 ko:K01878,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF1260.b3560,iAF987.Gmet_2942,iJO1366.b3560,iPC815.YPO4072,iY75_1357.Y75_RS19360 Bacteria 1TPW8@1239,3F3T8@33958,4HBCF@91061,COG0752@1,COG0752@2 NA|NA|NA J glycyl-tRNA synthetase alpha subunit GOKNOHPG_01394 405566.lhv_1300 2e-135 488.4 Lactobacillaceae recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1UZ19@1239,3F56P@33958,4HAHI@91061,COG1381@1,COG1381@2 NA|NA|NA L Involved in DNA repair and RecF pathway recombination GOKNOHPG_01395 326425.lhe_1180 1.4e-167 595.5 Lactobacillaceae era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 ko:K03595,ko:K06883 ko00000,ko03009,ko03029 Bacteria 1TP3R@1239,3F3WQ@33958,4H9WF@91061,COG1159@1,COG1159@2 NA|NA|NA S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism GOKNOHPG_01396 1423748.BALB01000007_gene849 3.6e-91 340.9 Lactobacillaceae ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 1V6BU@1239,3F516@33958,4HIIE@91061,COG0319@1,COG0319@2 NA|NA|NA S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA GOKNOHPG_01397 405566.lhv_1303 6.1e-174 616.7 Lactobacillaceae phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06217 ko00000 Bacteria 1TP35@1239,3F4E7@33958,4HBD5@91061,COG1702@1,COG1702@2 NA|NA|NA T phosphate starvation-inducible protein PhoH GOKNOHPG_01398 326425.lhe_1183 2.7e-68 264.6 Lactobacillaceae yqeY ko:K09117 ko00000 Bacteria 1V6F2@1239,3F6I0@33958,4HIQP@91061,COG1610@1,COG1610@2 NA|NA|NA S YqeY-like protein GOKNOHPG_01399 1033837.WANG_0480 2e-22 110.9 Lactobacillaceae rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02970 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEHU@1239,3F81Y@33958,4HNPV@91061,COG0828@1,COG0828@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS21 family GOKNOHPG_01400 326425.lhe_1185 3.7e-151 540.8 Lactobacillaceae yqfL 2.7.11.33,2.7.4.28 ko:K09773 ko00000,ko01000 Bacteria 1TPG0@1239,3F3WK@33958,4HB0Q@91061,COG1806@1,COG1806@2 NA|NA|NA F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation GOKNOHPG_01401 748671.LCRIS_01833 6.2e-10 69.3 Lactobacillaceae Bacteria 1U8GB@1239,29QQF@1,30BQ8@2,3FAYA@33958,4IIE4@91061 NA|NA|NA GOKNOHPG_01402 326425.lhe_0365 4.1e-32 144.4 Lactobacillaceae yozG ko:K07727 ko00000,ko03000 Bacteria 1VESP@1239,3F802@33958,4HPRB@91061,COG3655@1,COG3655@2 NA|NA|NA K Transcriptional regulator GOKNOHPG_01403 405566.lhv_1121 3.2e-48 197.6 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TRNY@1239,3F55P@33958,4HBKP@91061,COG0675@1,COG0675@2 NA|NA|NA L transposase, IS605 OrfB family GOKNOHPG_01404 1033837.WANG_1070 2.4e-83 314.7 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TRNY@1239,3F55P@33958,4HBKP@91061,COG0675@1,COG0675@2 NA|NA|NA L transposase, IS605 OrfB family GOKNOHPG_01405 405566.lhv_1850 6.2e-54 216.5 Lactobacillaceae Bacteria 1U65A@1239,29P5G@1,30A3N@2,3F737@33958,4IFV3@91061 NA|NA|NA S Enterocin A Immunity GOKNOHPG_01406 326425.lhe_0364 3.7e-13 79.7 Lactobacillaceae Bacteria 1U65A@1239,29P5G@1,30A3N@2,3F737@33958,4IFV3@91061 NA|NA|NA S Enterocin A Immunity GOKNOHPG_01407 1033837.WANG_1166 7e-211 740.0 Lactobacillaceae ko:K06921 ko00000 Bacteria 1TR21@1239,3F57U@33958,4HF7F@91061,COG1672@1,COG1672@2 NA|NA|NA S Archaea bacterial proteins of unknown function GOKNOHPG_01408 405566.lhv_1852 4.5e-140 503.8 Lactobacillaceae racD 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 R00491 RC00302 ko00000,ko00001,ko01000 Bacteria 1TQ6M@1239,3FCEP@33958,4HR12@91061,COG1794@1,COG1794@2 NA|NA|NA M Belongs to the aspartate glutamate racemases family GOKNOHPG_01409 326425.lhe_0361 9.7e-302 1042.0 Lactobacillaceae murE 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 Bacteria 1TPQE@1239,3F3UE@33958,4H9T1@91061,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan GOKNOHPG_01410 326425.lhe_0360 6.6e-207 726.5 Lactobacillaceae hpk31 2.7.13.3 ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TRZ0@1239,3FC2N@33958,4H9U1@91061,COG5002@1,COG5002@2 NA|NA|NA T His Kinase A (phospho-acceptor) domain GOKNOHPG_01411 405566.lhv_1855 5.1e-122 443.7 Lactobacillaceae Bacteria 1TP9M@1239,3F3Y0@33958,4HB3T@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator GOKNOHPG_01412 1423748.BALB01000012_gene1228 0.0 1158.7 Lactobacillaceae ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter GOKNOHPG_01413 326425.lhe_0357 9.6e-295 1018.8 Lactobacillaceae ko:K06147,ko:K06148,ko:K18891 ko02010,map02010 M00708 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 Bacteria 1TP0B@1239,3F3SP@33958,4H9SC@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter, ATP-binding protein GOKNOHPG_01414 326425.lhe_0356 4.6e-135 487.3 Lactobacillaceae XK27_01040 Bacteria 1VF5N@1239,3F4JS@33958,4HH7B@91061,COG4858@1,COG4858@2 NA|NA|NA S Protein of unknown function (DUF1129) GOKNOHPG_01415 326425.lhe_0355 2.3e-201 708.0 Lactobacillaceae ychF GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 ko:K06942 ko00000,ko03009 Bacteria 1TPRK@1239,3F3TK@33958,4H9SQ@91061,COG0012@1,COG0012@2 NA|NA|NA J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner GOKNOHPG_01416 326425.lhe_0354 3.7e-44 183.7 Lactobacillaceae yyzM Bacteria 1VEQ7@1239,3F823@33958,4HNHU@91061,COG4481@1,COG4481@2 NA|NA|NA S Bacterial protein of unknown function (DUF951) GOKNOHPG_01417 405566.lhv_1864 1.7e-154 552.0 Lactobacillaceae spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 1TQ2B@1239,3F47R@33958,4H9TB@91061,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family GOKNOHPG_01418 326425.lhe_0352 9.2e-136 489.6 Lactobacillaceae soj ko:K03496 ko00000,ko03036,ko04812 Bacteria 1TP8S@1239,3F4AE@33958,4HAYM@91061,COG1192@1,COG1192@2 NA|NA|NA D Sporulation initiation inhibitor GOKNOHPG_01419 326425.lhe_0351 7.3e-147 526.6 Lactobacillaceae noc ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 1TP0I@1239,3F4RU@33958,4HAC6@91061,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family GOKNOHPG_01420 326425.lhe_0350 1e-128 466.1 Lactobacillaceae rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 ko00000,ko01000,ko03009,ko03036 Bacteria 1TPBT@1239,3F3ZX@33958,4HAAZ@91061,COG0357@1,COG0357@2 NA|NA|NA J Specifically methylates the N7 position of a guanine in 16S rRNA GOKNOHPG_01421 405566.lhv_1868 7.3e-84 316.6 Lactobacillaceae cvpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 ko:K03558 ko00000 Bacteria 1U58E@1239,3F552@33958,4IEZI@91061,COG1286@1,COG1286@2 NA|NA|NA S Colicin V production protein GOKNOHPG_01422 326425.lhe_0141 2.1e-145 521.5 Lactobacillaceae rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469,ko:K06993 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1V4A0@1239,3F3RG@33958,4HHJ9@91061,COG0328@1,COG0328@2,COG3341@1,COG3341@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids GOKNOHPG_01423 405566.lhv_0133 1.6e-137 495.7 Lactobacillaceae ypuA Bacteria 1UY79@1239,3F416@33958,4HAZ5@91061,COG4086@1,COG4086@2 NA|NA|NA S Protein of unknown function (DUF1002) GOKNOHPG_01424 405566.lhv_0134 1.2e-157 562.4 Lactobacillaceae epsV 2.7.8.12 ko:K09809 ko00000,ko01000 Bacteria 1VATJ@1239,3F52I@33958,4HNAP@91061,COG1216@1,COG1216@2 NA|NA|NA S glycosyl transferase family 2 GOKNOHPG_01425 326425.lhe_0144 2.3e-124 451.4 Lactobacillaceae Bacteria 1TSFW@1239,3F5BW@33958,4HI0M@91061,COG0596@1,COG0596@2 NA|NA|NA S Alpha/beta hydrolase family GOKNOHPG_01426 326425.lhe_0145 3.3e-115 421.0 Lactobacillaceae Bacteria 1UJSC@1239,3F4ZZ@33958,4HCVT@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family GOKNOHPG_01427 326425.lhe_0146 3.3e-55 221.1 Lactobacillaceae Bacteria 1U6HK@1239,29PF3@1,30AD9@2,3F7XT@33958,4IG9W@91061 NA|NA|NA GOKNOHPG_01428 405566.lhv_0137 2e-180 638.3 Lactobacillaceae prs 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2848 Bacteria 1TQ6Q@1239,3F3V8@33958,4HB61@91061,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) GOKNOHPG_01429 405566.lhv_0138 3e-114 417.9 Lactobacillaceae luxT Bacteria 1VZKY@1239,3F43G@33958,4HM1C@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family GOKNOHPG_01430 326425.lhe_0149 6.7e-129 466.8 Lactobacillaceae Bacteria 1U516@1239,2CCK0@1,309GI@2,3F3YE@33958,4IESZ@91061 NA|NA|NA GOKNOHPG_01431 326425.lhe_0150 1.3e-260 905.2 Lactobacillaceae glnPH2 ko:K02029,ko:K02030,ko:K17073,ko:K17074 ko02010,map02010 M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1TPM3@1239,3F48Y@33958,4HAS2@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2 NA|NA|NA P ABC transporter permease GOKNOHPG_01432 326425.lhe_0151 8.4e-131 473.0 Lactobacillaceae glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein GOKNOHPG_01433 326425.lhe_0152 9.5e-228 795.8 Lactobacillaceae Bacteria 1V1IM@1239,3F3QG@33958,4HRX1@91061,COG2340@1,COG2340@2 NA|NA|NA S Cysteine-rich secretory protein family GOKNOHPG_01434 1423748.BALB01000006_gene775 8.4e-204 716.1 Lactobacillaceae ddl 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TP2Y@1239,3F41Z@33958,4H9KB@91061,COG1181@1,COG1181@2 NA|NA|NA F Belongs to the D-alanine--D-alanine ligase family GOKNOHPG_01435 405566.lhv_0144 3e-88 331.6 Lactobacillaceae Bacteria 1VN62@1239,2EIZT@1,33CQY@2,3F5GU@33958,4HRPP@91061 NA|NA|NA GOKNOHPG_01436 405566.lhv_0145 2.4e-201 708.0 Lactobacillaceae yibE Bacteria 1TPEV@1239,3F3M9@33958,4HCP3@91061,COG5438@1,COG5438@2 NA|NA|NA S overlaps another CDS with the same product name GOKNOHPG_01437 326425.lhe_0156 1.7e-129 468.8 Lactobacillaceae yibF Bacteria 1TSWX@1239,3F3S6@33958,4HBKX@91061,COG5438@1,COG5438@2 NA|NA|NA S overlaps another CDS with the same product name GOKNOHPG_01438 1321784.HMPREF1987_00140 2.7e-18 99.8 Clostridia Bacteria 1W0F0@1239,253Z6@186801,2DYQM@1,34APZ@2 NA|NA|NA GOKNOHPG_01439 1545702.LACWKB8_1664 4.9e-245 853.6 Lactobacillaceae Bacteria 1V08F@1239,3FBEY@33958,4HUKE@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region GOKNOHPG_01440 1033837.WANG_0617 4.5e-60 237.7 Lactobacillaceae Bacteria 1U5RF@1239,2A1GN@1,30PQ9@2,3F6DA@33958,4IFFK@91061 NA|NA|NA GOKNOHPG_01441 1033837.WANG_0622 1.9e-231 808.1 Lactobacillaceae yrvN ko:K07478 ko00000 Bacteria 1TPVV@1239,3F44J@33958,4HAIS@91061,COG2256@1,COG2256@2 NA|NA|NA L AAA C-terminal domain GOKNOHPG_01442 1033837.WANG_0623 8.3e-146 523.1 Lactobacillaceae glxR 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 iJN678.mmsB Bacteria 1TR4F@1239,3F3XC@33958,4H9MA@91061,COG2084@1,COG2084@2 NA|NA|NA I Dehydrogenase GOKNOHPG_01443 324831.LGAS_0985 2.2e-34 151.4 Lactobacillaceae Bacteria 1V6Z8@1239,3F6WQ@33958,4HMP7@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) family GOKNOHPG_01444 324831.LGAS_0985 4.1e-10 69.3 Lactobacillaceae Bacteria 1V6Z8@1239,3F6WQ@33958,4HMP7@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) family GOKNOHPG_01445 1423748.BALB01000020_gene1608 1.4e-110 405.6 Lactobacillaceae rcfA 4.1.99.16,4.2.3.22,4.2.3.75 ko:K10187,ko:K21562 ko00909,ko01100,ko01110,map00909,map01100,map01110 R07647,R07648,R08543,R09487 RC01832,RC02159,RC02160,RC02183,RC02425,RC02552 ko00000,ko00001,ko01000,ko03000 Bacteria 1V3XW@1239,3F4YM@33958,4HDG1@91061,COG0664@1,COG0664@2 NA|NA|NA K Transcriptional regulator, Crp Fnr family GOKNOHPG_01446 1423748.BALB01000020_gene1609 4.6e-89 334.0 Lactobacillaceae dps ko:K04047 ko00000,ko03036 Bacteria 1VB1X@1239,3F4SN@33958,4HMJG@91061,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family GOKNOHPG_01447 1423748.BALB01000020_gene1610 6e-35 152.9 Lactobacillaceae copZ ko:K07213 ko04978,map04978 ko00000,ko00001 Bacteria 1VK5F@1239,3FBN8@33958,4IRA3@91061,COG2608@1,COG2608@2 NA|NA|NA C Heavy-metal-associated domain GOKNOHPG_01448 1033837.WANG_0627 0.0 1152.9 Lactobacillaceae cadA 3.6.3.3,3.6.3.5 ko:K01534 ko00000,ko01000 3.A.3.6 Bacteria 1TQ07@1239,3FC0Y@33958,4HT7C@91061,COG2217@1,COG2217@2 NA|NA|NA P E1-E2 ATPase GOKNOHPG_01449 1423790.BN53_01125 1.1e-96 359.4 Lactobacillaceae Bacteria 1TP9A@1239,3F4TJ@33958,4H9NW@91061,COG3344@1,COG3344@2 NA|NA|NA L PFAM RNA-directed DNA polymerase (Reverse transcriptase) GOKNOHPG_01450 1033837.WANG_0639 1.7e-118 432.2 Lactobacillaceae ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1UZXK@1239,3F41Q@33958,4HUWT@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator GOKNOHPG_01451 585524.HMPREF0493_0564 7.2e-261 906.0 Lactobacillaceae npr 1.11.1.1 ko:K05910 ko00000,ko01000 Bacteria 1TPWW@1239,3F449@33958,4H9U7@91061,COG0446@1,COG0446@2 NA|NA|NA C NADH oxidase GOKNOHPG_01452 585524.HMPREF0493_0563 6.1e-67 260.0 Lactobacillaceae GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K07006 ko00000 Bacteria 1VGE7@1239,3F6YB@33958,4HNE7@91061,COG3576@1,COG3576@2 NA|NA|NA S pyridoxamine 5-phosphate GOKNOHPG_01453 585524.HMPREF0493_0562 4.9e-168 597.0 Lactobacillaceae yobV1 Bacteria 1TPS2@1239,3F56I@33958,4HDVX@91061,COG2378@1,COG2378@2 NA|NA|NA K WYL domain GOKNOHPG_01454 585524.HMPREF0493_0561 1.1e-80 305.8 Lactobacillaceae XK26_02160 Bacteria 1U621@1239,3F6UR@33958,4IFR1@91061,COG5015@1,COG5015@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase GOKNOHPG_01455 405566.lhv_0015 1.4e-58 233.0 Lactobacillaceae Bacteria 1U59E@1239,29DXA@1,300V7@2,3F59A@33958,4IF0P@91061 NA|NA|NA S SLAP domain GOKNOHPG_01456 525365.HMPREF0548_1401 5.6e-35 153.7 Lactobacillaceae Bacteria 1U59E@1239,29DXA@1,300V7@2,3F59A@33958,4IF0P@91061 NA|NA|NA S SLAP domain GOKNOHPG_01457 1545701.LACWKB10_0255 4.5e-134 484.6 Lactobacillaceae Bacteria 1TRUT@1239,3F5PJ@33958,4HFIF@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GOKNOHPG_01458 525365.HMPREF0548_0015 3.2e-93 348.2 Lactobacillaceae ko:K01992,ko:K06994 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1UHYG@1239,3F58P@33958,4IT95@91061,COG1511@1,COG1511@2 NA|NA|NA S domain protein GOKNOHPG_01459 1033837.WANG_0653 2.5e-133 481.5 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1UHTY@1239,3FBTX@33958,4ISIK@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter GOKNOHPG_01460 1033837.WANG_0653 1.1e-18 98.2 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1UHTY@1239,3FBTX@33958,4ISIK@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter GOKNOHPG_01461 1033837.WANG_1133 1.1e-38 165.6 Lactobacillaceae Bacteria 1VNI3@1239,3F5J9@33958,4HSHZ@91061,COG3548@1,COG3548@2 NA|NA|NA S Protein of unknown function (DUF1211) GOKNOHPG_01462 326425.lhe_0552 6.7e-170 603.2 Lactobacillaceae yegS GO:0001727,GO:0003674,GO:0003824,GO:0004143,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0030258,GO:0044237,GO:0044238,GO:0044255,GO:0046834,GO:0071704 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 R02240 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TQAU@1239,3F447@33958,4H9WD@91061,COG1597@1,COG1597@2 NA|NA|NA G Lipid kinase GOKNOHPG_01463 405566.lhv_0555 5e-273 946.4 Lactobacillaceae gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 ko:K01876,ko:K02434 ko00970,ko01100,map00970,map01100 M00359,M00360 R03905,R04212,R05577 RC00010,RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPG3@1239,3F44H@33958,4HAFB@91061,COG0064@1,COG0064@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) GOKNOHPG_01464 326425.lhe_0550 1.1e-259 902.1 Lactobacillaceae gatA 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 1TP0C@1239,3F4BK@33958,4HBAZ@91061,COG0154@1,COG0154@2 NA|NA|NA J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) GOKNOHPG_01465 405566.lhv_0553 5.2e-50 203.4 Lactobacillaceae gatC 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 iAF987.Gmet_0076 Bacteria 1VEK3@1239,3F7XB@33958,4HNNA@91061,COG0721@1,COG0721@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) GOKNOHPG_01466 326425.lhe_0548 1.5e-206 725.3 Lactobacillaceae camS Bacteria 1TSYE@1239,3F3KI@33958,4HBI8@91061,COG4851@1,COG4851@2 NA|NA|NA S sex pheromone GOKNOHPG_01467 326425.lhe_0547 0.0 1308.1 Lactobacillaceae ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1TPQ3@1239,3F43C@33958,4HA1D@91061,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA GOKNOHPG_01468 405566.lhv_0550 0.0 1460.7 Lactobacillaceae pcrA 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPSU@1239,3F400@33958,4HB12@91061,COG0210@1,COG0210@2 NA|NA|NA L ATP-dependent DNA helicase GOKNOHPG_01469 272621.LBA0527 2.9e-103 381.3 Lactobacillaceae acmC 3.2.1.17,3.2.1.96 ko:K01185,ko:K01227,ko:K02395 ko00511,map00511 ko00000,ko00001,ko01000,ko02035 Bacteria 1V7JY@1239,3F584@33958,4HIY4@91061,COG1705@1,COG1705@2 NA|NA|NA NU mannosyl-glycoprotein GOKNOHPG_01471 326425.lhe_0543 6.9e-86 323.2 Lactobacillaceae ydcK ko:K03095 ko00000 Bacteria 1V6NU@1239,3F703@33958,4HIHY@91061,COG3091@1,COG3091@2 NA|NA|NA S Belongs to the SprT family GOKNOHPG_01472 405566.lhv_0548 4.8e-136 490.3 Lactobacillaceae Bacteria 1V9J7@1239,3F4U2@33958,4HIAM@91061,COG3774@1,COG3774@2 NA|NA|NA M Glycosyltransferase sugar-binding region containing DXD motif GOKNOHPG_01473 326425.lhe_0541 1.1e-256 892.1 Lactobacillaceae epsU Bacteria 1TRTX@1239,3FB7P@33958,4HDWM@91061,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein GOKNOHPG_01474 405566.lhv_0546 3e-223 780.8 Lactobacillaceae Bacteria 1VD8C@1239,3F52X@33958,4HI8C@91061,COG1887@1,COG1887@2 NA|NA|NA M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase GOKNOHPG_01475 1423748.BALB01000004_gene503 0.0 1309.7 Lactobacillaceae pacL 3.6.3.8 ko:K01537 ko00000,ko01000 3.A.3.2 Bacteria 1TPF5@1239,3F3KP@33958,4H9S5@91061,COG0474@1,COG0474@2 NA|NA|NA P P-type ATPase GOKNOHPG_01476 1423748.BALB01000004_gene503 2.8e-60 238.0 Lactobacillaceae pacL 3.6.3.8 ko:K01537 ko00000,ko01000 3.A.3.2 Bacteria 1TPF5@1239,3F3KP@33958,4H9S5@91061,COG0474@1,COG0474@2 NA|NA|NA P P-type ATPase GOKNOHPG_01477 1033837.WANG_0286 1.7e-235 821.6 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3FCFA@33958,4HC8M@91061,COG2801@1,COG2801@2 NA|NA|NA L COG2963 Transposase and inactivated derivatives GOKNOHPG_01478 1116231.SMA_1824 6.6e-171 606.7 Bacilli wbbI GO:0003674,GO:0003824,GO:0008194,GO:0008378,GO:0008921,GO:0016740,GO:0016757,GO:0016758,GO:0035250 iAF1260.b2034,iBWG_1329.BWG_1824,iECDH10B_1368.ECDH10B_2184,iECDH1ME8569_1439.ECDH1ME8569_1971,iECSF_1327.ECSF_1923,iEcDH1_1363.EcDH1_1623,iJO1366.b2034,iY75_1357.Y75_RS10645 Bacteria 1V8J0@1239,4HITN@91061,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups GOKNOHPG_01479 220668.lp_1176 1.5e-192 678.7 Lactobacillaceae glf GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 iNJ661.Rv3809c Bacteria 1TQB9@1239,3F52G@33958,4HB5F@91061,COG0562@1,COG0562@2 NA|NA|NA M UDP-galactopyranose mutase GOKNOHPG_01480 203123.OEOE_0357 2.8e-163 581.3 Bacilli ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1UZ8W@1239,4HE3B@91061,COG0598@1,COG0598@2 NA|NA|NA P CorA-like Mg2+ transporter protein GOKNOHPG_01481 326425.lhe_0278 1.6e-33 148.3 Lactobacillaceae GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 ko:K14060 ko00000 Bacteria 1V51N@1239,3F51V@33958,4HDX2@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain GOKNOHPG_01482 862514.HMPREF0623_1589 3.8e-45 187.2 Lactobacillaceae alwI Bacteria 1UPNM@1239,2DBCK@1,2Z8EF@2,3F7YT@33958,4HNIC@91061 NA|NA|NA L AlwI restriction endonuclease GOKNOHPG_01486 797515.HMPREF9103_01291 1e-43 183.0 Lactobacillaceae hprA 1.1.1.29 ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCX@1239,3F4Z6@33958,4HASY@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family GOKNOHPG_01487 797515.HMPREF9103_01291 8.1e-56 223.0 Lactobacillaceae hprA 1.1.1.29 ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCX@1239,3F4Z6@33958,4HASY@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family GOKNOHPG_01488 1423780.LOT_0173 1.5e-32 145.6 Lactobacillaceae Bacteria 1TSZZ@1239,3F49K@33958,4HB54@91061,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase GOKNOHPG_01489 1423780.LOT_0174 1.1e-113 416.0 Lactobacillaceae pgmB GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008801,GO:0009058,GO:0009292,GO:0009294,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016853,GO:0016866,GO:0016868,GO:0019203,GO:0030312,GO:0033554,GO:0034637,GO:0040007,GO:0042221,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046351,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0071704,GO:0071944,GO:1901576 2.4.1.64,3.1.3.12,3.2.1.28,5.4.2.6 ko:K01087,ko:K01194,ko:K01838,ko:K05342 ko00500,ko01100,map00500,map01100 R00010,R02727,R02728,R02778,R11310 RC00017,RC00049,RC00408 ko00000,ko00001,ko00537,ko01000 GH37,GH65 Bacteria 1UY8N@1239,3F4ST@33958,4HF3K@91061,COG0637@1,COG0637@2 NA|NA|NA S beta-phosphoglucomutase GOKNOHPG_01490 511437.Lbuc_1257 0.0 1580.5 Lactobacillaceae trePP GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0030312,GO:0044464,GO:0071944 2.4.1.216,2.4.1.8,3.1.3.12,3.2.1.28 ko:K00691,ko:K01087,ko:K01194,ko:K03731 ko00500,ko01100,map00500,map01100 R00010,R01555,R02778 RC00017,RC00049 ko00000,ko00001,ko00537,ko01000 GH37,GH65 Bacteria 1TQMB@1239,3F4TB@33958,4HD7Z@91061,COG1554@1,COG1554@2 NA|NA|NA G Glycosyl hydrolase family 65 central catalytic domain GOKNOHPG_01491 1329250.WOSG25_300030 1e-31 142.5 Bacilli ko:K07483 ko00000 Bacteria 1VEWG@1239,4HX6Y@91061,COG2963@1,COG2963@2 NA|NA|NA L Transposase and inactivated derivatives GOKNOHPG_01492 1329250.WOSG25_160320 1.4e-49 202.6 Bacilli ko:K07497 ko00000 Bacteria 1TU21@1239,4HDK4@91061,COG2801@1,COG2801@2 NA|NA|NA L COG2801 Transposase and inactivated derivatives GOKNOHPG_01494 220668.lp_2425 3.2e-12 77.4 Lactobacillaceae Bacteria 1W4M5@1239,2911N@1,2ZNP8@2,3F95E@33958,4I18X@91061 NA|NA|NA GOKNOHPG_01498 60520.HR47_13545 1.4e-45 189.1 Lactobacillaceae arpU Bacteria 1VJNE@1239,2DPRG@1,3333C@2,3FB8F@33958,4HPDS@91061 NA|NA|NA S Transcriptional regulator, ArpU family GOKNOHPG_01499 220668.lp_0655 9.2e-17 92.0 Lactobacillaceae Bacteria 1U76U@1239,29PXZ@1,30AWD@2,3F91U@33958,4IH1M@91061 NA|NA|NA GOKNOHPG_01501 1400520.LFAB_17310 4.1e-19 99.8 Lactobacillaceae traA Bacteria 1VQWC@1239,3F4DP@33958,4HD6B@91061,COG0507@1,COG0507@2 NA|NA|NA L MobA MobL family protein GOKNOHPG_01502 405566.lhv_1172 1.9e-36 157.9 Lactobacillaceae mmuM GO:0003674,GO:0003824,GO:0005488,GO:0006575,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008270,GO:0008757,GO:0008898,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033477,GO:0033554,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:1901564 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHQ5@1239,3F4UT@33958,4HAS6@91061,COG2040@1,COG2040@2 NA|NA|NA H homocysteine S-methyltransferase GOKNOHPG_01503 405566.lhv_1171 2.4e-228 797.7 Lactobacillaceae amd 3.5.1.47 ko:K01436,ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPD7@1239,3FC42@33958,4H9WQ@91061,COG1473@1,COG1473@2 NA|NA|NA E Peptidase family M20/M25/M40 GOKNOHPG_01504 326425.lhe_1069 5.4e-229 800.0 Lactobacillaceae steT GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ48@1239,3F3YJ@33958,4HBGT@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid GOKNOHPG_01505 353496.LBU_0205 3.3e-59 234.2 Lactobacillaceae pdxH ko:K07006 ko00000 Bacteria 1VW4G@1239,3F6IW@33958,4HW37@91061,COG3576@1,COG3576@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase GOKNOHPG_01506 1033837.WANG_1725 5.4e-147 526.9 Lactobacillaceae cbiO2 ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TQAV@1239,3F5M4@33958,4HCMA@91061,COG1122@1,COG1122@2 NA|NA|NA P ABC transporter GOKNOHPG_01507 1033837.WANG_1724 6e-157 560.1 Lactobacillaceae ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1VTBJ@1239,3F4XB@33958,4HVE5@91061,COG1122@1,COG1122@2 NA|NA|NA P ABC transporter GOKNOHPG_01508 1033837.WANG_1723 3.7e-132 477.6 Lactobacillaceae cbiQ ko:K02008,ko:K16785 ko02010,map02010 M00245,M00246,M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1UYQQ@1239,3F5GJ@33958,4HFDP@91061,COG0619@1,COG0619@2 NA|NA|NA P Cobalt transport protein GOKNOHPG_01509 944562.HMPREF9102_2135 1e-89 336.3 Lactobacillaceae 2.7.7.65 ko:K16923,ko:K18967 M00582 ko00000,ko00002,ko01000,ko02000 3.A.1.28,9.B.34.1.1 Bacteria 1UZUT@1239,3F4G1@33958,4HMC0@91061,COG3275@1,COG3275@2 NA|NA|NA T phosphorelay sensor kinase activity GOKNOHPG_01510 1423754.BALY01000067_gene768 2.8e-46 191.0 Lactobacillaceae Bacteria 1UZVH@1239,2BVJW@1,32QXP@2,3F6CN@33958,4HFK6@91061 NA|NA|NA S Uncharacterised protein family (UPF0236) GOKNOHPG_01511 1033837.WANG_1752 5.3e-124 450.7 Lactobacillaceae Bacteria 1UZVH@1239,2BVJW@1,32QXP@2,3F6CN@33958,4HFK6@91061 NA|NA|NA S Uncharacterised protein family (UPF0236) GOKNOHPG_01512 326425.lhe_1067 0.0 1278.8 Lactobacillaceae pepO 3.4.24.71 ko:K01415,ko:K07386 ko00000,ko01000,ko01002,ko04147 Bacteria 1TQTA@1239,3F4CX@33958,4HDSF@91061,COG3590@1,COG3590@2 NA|NA|NA O Peptidase family M13 GOKNOHPG_01513 326425.lhe_1066 1.2e-59 236.1 Lactobacillaceae ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0409 Bacteria 1TQ22@1239,3F48Z@33958,4HA7K@91061,COG0282@1,COG0282@2 NA|NA|NA F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction GOKNOHPG_01514 326425.lhe_1065 3.6e-302 1043.5 Lactobacillaceae XK27_11280 Bacteria 1TQFA@1239,2BW99@1,2Z7PD@2,3F4D7@33958,4HC1J@91061 NA|NA|NA S Psort location CytoplasmicMembrane, score GOKNOHPG_01515 1423767.BALU01000003_gene1008 0.0 1179.9 Lactobacillaceae ko:K09384 ko00000 Bacteria 1TPQU@1239,3F47M@33958,4HBI0@91061,COG3410@1,COG3410@2 NA|NA|NA N Uncharacterized conserved protein (DUF2075) GOKNOHPG_01516 748671.LCRIS_00733 1.9e-223 781.6 Lactobacillaceae ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1VT70@1239,3FCAG@33958,4HUMC@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease GOKNOHPG_01517 1033837.WANG_0930 8.6e-37 159.1 Lactobacillaceae ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1VT70@1239,3FCAG@33958,4HUMC@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease GOKNOHPG_01519 326425.lhe_0735 4e-29 133.3 Lactobacillaceae rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEF6@1239,3F7TS@33958,4HNKX@91061,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site GOKNOHPG_01520 326425.lhe_0736 2e-86 325.1 Lactobacillaceae Bacteria 1VF6Q@1239,3F57S@33958,4HMDE@91061,COG5652@1,COG5652@2 NA|NA|NA S VanZ like family GOKNOHPG_01521 326425.lhe_0737 2.6e-132 478.0 Lactobacillaceae yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 Bacteria 1TPP5@1239,3F4WF@33958,4H9WJ@91061,COG0217@1,COG0217@2 NA|NA|NA K Transcriptional regulatory protein GOKNOHPG_01522 326425.lhe_0738 3.9e-176 624.0 Lactobacillaceae comGA ko:K02243 M00429 ko00000,ko00002,ko02044 3.A.14.1 Bacteria 1TPGE@1239,3F4HY@33958,4HB0C@91061,COG2804@1,COG2804@2 NA|NA|NA NU Type II IV secretion system protein GOKNOHPG_01523 326425.lhe_0739 3.2e-173 614.4 Lactobacillaceae comGB ko:K02244 M00429 ko00000,ko00002,ko02044 3.A.14.1 Bacteria 1U00C@1239,3F3S9@33958,4HGUA@91061,COG1459@1,COG1459@2 NA|NA|NA NU type II secretion system GOKNOHPG_01524 326425.lhe_0740 4.1e-43 180.6 Lactobacillaceae comGC GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 ko:K02245,ko:K02456 ko03070,ko05111,map03070,map05111 M00331,M00429 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1VFI9@1239,3F7ZC@33958,4HNNT@91061,COG4537@1,COG4537@2 NA|NA|NA U competence protein ComGC GOKNOHPG_01525 326425.lhe_0741 6.8e-72 276.6 Lactobacillaceae ko:K02246 M00429 ko00000,ko00002,ko02044 Bacteria 1U645@1239,29ZCH@1,30MB3@2,3F6ZT@33958,4IFTR@91061 NA|NA|NA GOKNOHPG_01526 326425.lhe_0742 1e-41 175.6 Lactobacillaceae Bacteria 1U6G6@1239,2BS3U@1,32M4K@2,3F7UI@33958,4IG89@91061 NA|NA|NA GOKNOHPG_01527 326425.lhe_0743 2.1e-80 305.1 Lactobacillaceae comGF ko:K02246,ko:K02248 M00429 ko00000,ko00002,ko02044 Bacteria 1U6NI@1239,3F87B@33958,4IGFH@91061,COG4940@1,COG4940@2 NA|NA|NA U Putative Competence protein ComGF GOKNOHPG_01528 405566.lhv_0784 3e-187 661.0 Lactobacillaceae ytxK 2.1.1.72 ko:K00571 ko00000,ko01000,ko02048 Bacteria 1TRIQ@1239,3F4CI@33958,4H9SE@91061,COG0827@1,COG0827@2 NA|NA|NA L N-6 DNA Methylase GOKNOHPG_01529 326425.lhe_0745 1.4e-220 771.9 Lactobacillaceae ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0409 Bacteria 1TQ22@1239,3F48Z@33958,4HA7K@91061,COG0282@1,COG0282@2 NA|NA|NA F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction GOKNOHPG_01531 1399941.U3PCM7_9CAUD 3.4e-44 184.9 Siphoviridae GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0015074,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360 Viruses 4QAQE@10239,4QKN9@10699,4QPDM@28883,4QUYF@35237 NA|NA|NA S Phage integrase family GOKNOHPG_01532 575606.HMPREF0525_00592 1.1e-31 143.3 Lactobacillaceae sip Bacteria 1TTJI@1239,3F4IB@33958,4HDG6@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family GOKNOHPG_01536 97137.C821_00559 1e-18 100.9 Lactobacillaceae Bacteria 1UI8W@1239,3F6SG@33958,4ISGD@91061,COG3152@1,COG3152@2 NA|NA|NA S Membrane GOKNOHPG_01537 326425.lhe_1055 6.2e-15 87.8 Lactobacillaceae Bacteria 1VI5W@1239,2E37J@1,32Y79@2,3F8SQ@33958,4HP73@91061 NA|NA|NA GOKNOHPG_01539 891391.LAC30SC_06705 2.9e-25 121.3 Lactobacillaceae Bacteria 1VEKB@1239,3FBRQ@33958,4HNIW@91061,COG1476@1,COG1476@2 NA|NA|NA K Cro/C1-type HTH DNA-binding domain GOKNOHPG_01541 272621.LBA0742 1.5e-25 121.7 Lactobacillaceae Bacteria 1TQXN@1239,3F4Y5@33958,4HBHT@91061,COG5434@1,COG5434@2 NA|NA|NA M Protein of unknown function (DUF3737) GOKNOHPG_01542 405566.lhv_0690 3.3e-158 564.3 Lactobacillaceae coiA 3.6.4.12 ko:K03657,ko:K06198 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TRGD@1239,3F4BZ@33958,4HFP5@91061,COG4469@1,COG4469@2 NA|NA|NA S Competence protein GOKNOHPG_01543 326425.lhe_0659 1.5e-132 478.8 Lactobacillaceae mecA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K16511 ko00000 Bacteria 1UZ7D@1239,3F5G4@33958,4HID6@91061,COG4862@1,COG4862@2 NA|NA|NA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis GOKNOHPG_01544 1423748.BALB01000004_gene614 2.3e-66 258.1 Lactobacillaceae spxA 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1V3QC@1239,3F6HJ@33958,4HH0I@91061,COG1393@1,COG1393@2 NA|NA|NA K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress GOKNOHPG_01545 326425.lhe_0657 2.1e-305 1054.3 Lactobacillaceae ptsI GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0008965,GO:0009401,GO:0016740,GO:0016772,GO:0016775,GO:0019197,GO:0032991,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 8.A.7 iB21_1397.B21_02277,iE2348C_1286.E2348C_2602,iEC042_1314.EC042_2625,iECBD_1354.ECBD_1265,iECB_1328.ECB_02316,iECD_1391.ECD_02316,iECH74115_1262.ECH74115_3647,iECIAI1_1343.ECIAI1_2474,iECIAI39_1322.ECIAI39_2562,iECO103_1326.ECO103_2935,iECO111_1330.ECO111_3146,iECO26_1355.ECO26_3469,iECP_1309.ECP_2440,iECSE_1348.ECSE_2707,iECSP_1301.ECSP_3364,iECUMN_1333.ECUMN_2738,iECW_1372.ECW_m2645,iECs_1301.ECs3288,iEKO11_1354.EKO11_1312,iEcE24377_1341.EcE24377A_2703,iEcHS_1320.EcHS_A2551,iEcSMS35_1347.EcSMS35_2571,iEcolC_1368.EcolC_1262,iLF82_1304.LF82_1770,iNRG857_1313.NRG857_12115,iSBO_1134.SBO_2440,iSDY_1059.SDY_2613,iSFV_1184.SFV_2468,iSF_1195.SF2471,iSFxv_1172.SFxv_2720,iSSON_1240.SSON_2505,iS_1188.S2617,iUMNK88_1353.UMNK88_3018,iWFL_1372.ECW_m2645,iZ_1308.Z3682 Bacteria 1TPK8@1239,3F3MS@33958,4H9VD@91061,COG1080@1,COG1080@2 NA|NA|NA G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) GOKNOHPG_01546 1423748.BALB01000004_gene612 8.5e-41 172.6 Lactobacillaceae ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 ko:K11189 ko00000,ko02000 4.A.2.1 Bacteria 1VA0R@1239,3F6XQ@33958,4HKGA@91061,COG1925@1,COG1925@2 NA|NA|NA G phosphocarrier protein HPR GOKNOHPG_01547 405566.lhv_0685 3.3e-26 123.6 Lactobacillaceae Bacteria 1U6MM@1239,29PIA@1,30AGF@2,3F85J@33958,4IGEE@91061 NA|NA|NA GOKNOHPG_01548 405566.lhv_0683 0.0 1335.5 Lactobacillaceae clpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03697 ko00000,ko03110 Bacteria 1TPMU@1239,3F3K9@33958,4HA0V@91061,COG0542@1,COG0542@2 NA|NA|NA O Belongs to the ClpA ClpB family GOKNOHPG_01549 1423748.BALB01000004_gene609 8.7e-44 182.6 Lactobacillaceae XK27_09445 Bacteria 1VFRS@1239,2EBZ8@1,335YI@2,3F70G@33958,4HNUK@91061 NA|NA|NA S Domain of unknown function (DUF1827) GOKNOHPG_01550 326425.lhe_0652 2.8e-301 1040.4 Lactobacillaceae prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02837,ko:K07133 ko00000,ko03012 Bacteria 1TPYT@1239,3F489@33958,4HADS@91061,COG4108@1,COG4108@2 NA|NA|NA J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP GOKNOHPG_01551 326425.lhe_0651 2.5e-158 564.7 Lactobacillaceae hlyX ko:K03699 ko00000,ko02042 Bacteria 1TPN0@1239,3F3KG@33958,4H9SB@91061,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain GOKNOHPG_01552 326425.lhe_0650 1.3e-73 282.3 Lactobacillaceae Bacteria 1U5U1@1239,2C070@1,300GJ@2,3F6I5@33958,4IFHZ@91061 NA|NA|NA GOKNOHPG_01553 326425.lhe_0649 5.4e-86 323.6 Lactobacillaceae Bacteria 1U5P0@1239,29NVN@1,309TR@2,3F693@33958,4IFDJ@91061 NA|NA|NA GOKNOHPG_01554 405566.lhv_0678 6.6e-145 520.0 Lactobacillaceae recX GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496 2.4.1.337 ko:K03565,ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003,ko03400 GT4 Bacteria 1V72V@1239,3F4BY@33958,4HJ7R@91061,COG2137@1,COG2137@2 NA|NA|NA S Regulatory protein RecX GOKNOHPG_01555 326425.lhe_0647 1.8e-259 901.4 Lactobacillaceae rumA 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 ko00000,ko01000,ko03009,ko03016 Bacteria 1TP4H@1239,3F4GQ@33958,4HA6M@91061,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family GOKNOHPG_01556 1423748.BALB01000004_gene601 1.5e-79 302.4 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TQYU@1239,3F43H@33958,4HC4H@91061,COG1073@1,COG1073@2 NA|NA|NA D Alpha beta GOKNOHPG_01557 405566.lhv_0620 1.6e-94 352.1 Lactobacillaceae Bacteria 1UZVA@1239,3F4KP@33958,4HH09@91061,COG3039@1,COG3039@2 NA|NA|NA L An automated process has identified a potential problem with this gene model GOKNOHPG_01558 525365.HMPREF0548_0665 4.1e-20 103.6 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TQYU@1239,3F43H@33958,4HC4H@91061,COG1073@1,COG1073@2 NA|NA|NA D Alpha beta GOKNOHPG_01559 326425.lhe_0593 1.4e-46 191.8 Lactobacillaceae Bacteria 1U6EZ@1239,29PCT@1,30AB1@2,3F7RU@33958,4IG6T@91061 NA|NA|NA GOKNOHPG_01560 405566.lhv_0663 9.6e-214 749.2 Lactobacillaceae mvaS 2.3.3.10 ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR4K@1239,3F425@33958,4HA67@91061,COG3425@1,COG3425@2 NA|NA|NA I Hydroxymethylglutaryl-CoA synthase GOKNOHPG_01561 405566.lhv_0662 1.2e-152 545.8 Lactobacillaceae mvaA 1.1.1.34,1.1.1.88,2.3.1.9 ko:K00021,ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,ko04152,ko04976,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020,map04152,map04976 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081,R02082 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TPNY@1239,3F3YY@33958,4HBQ3@91061,COG1257@1,COG1257@2 NA|NA|NA C Belongs to the HMG-CoA reductase family GOKNOHPG_01562 326425.lhe_0591 3.2e-57 227.6 Lactobacillaceae mvaA 1.1.1.34,1.1.1.88,2.3.1.9 ko:K00021,ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,ko04152,ko04976,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020,map04152,map04976 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081,R02082 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TPNY@1239,3F3YY@33958,4HBQ3@91061,COG1257@1,COG1257@2 NA|NA|NA C Belongs to the HMG-CoA reductase family GOKNOHPG_01563 326425.lhe_0590 5.6e-214 750.0 Lactobacillaceae atoB 1.1.1.88,2.3.1.9 ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TP07@1239,3F3Q5@33958,4H9RJ@91061,COG0183@1,COG0183@2 NA|NA|NA I Belongs to the thiolase family GOKNOHPG_01564 326425.lhe_0589 6.2e-168 596.7 Lactobacillaceae galU 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ24@1239,3F45A@33958,4HATY@91061,COG1210@1,COG1210@2 NA|NA|NA M UTP-glucose-1-phosphate uridylyltransferase GOKNOHPG_01565 326425.lhe_0588 1.2e-150 539.3 Lactobacillaceae yihY ko:K07058 ko00000 Bacteria 1U7HM@1239,3F4TC@33958,4H9MJ@91061,COG1295@1,COG1295@2 NA|NA|NA S Belongs to the UPF0761 family GOKNOHPG_01566 326425.lhe_0587 4.2e-163 580.5 Lactobacillaceae map GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 1TQC1@1239,3F3MK@33958,4H9S9@91061,COG0024@1,COG0024@2 NA|NA|NA E Methionine Aminopeptidase GOKNOHPG_01567 326425.lhe_0586 1.6e-79 302.0 Lactobacillaceae fld ko:K03839 ko00000 Bacteria 1V7AG@1239,3F6HY@33958,4HMJF@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin GOKNOHPG_01568 405566.lhv_0653 3.8e-88 330.9 Lactobacillaceae gtcA GO:0000166,GO:0003674,GO:0003824,GO:0003870,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009987,GO:0016020,GO:0016410,GO:0016491,GO:0016620,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0016903,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 Bacteria 1VESW@1239,3F4GH@33958,4HNK7@91061,COG2246@1,COG2246@2 NA|NA|NA S Teichoic acid glycosylation protein GOKNOHPG_01569 405566.lhv_0652 6.5e-215 753.1 Lactobacillaceae mnaA 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1TQZT@1239,3F3KQ@33958,4HBI3@91061,COG0381@1,COG0381@2 NA|NA|NA G Belongs to the UDP-N-acetylglucosamine 2-epimerase family GOKNOHPG_01570 326425.lhe_0583 1.3e-25 121.7 Lactobacillaceae Bacteria 1U6PN@1239,29PJM@1,30AHS@2,3F89D@33958,4IGGM@91061 NA|NA|NA GOKNOHPG_01572 326425.lhe_0581 9.2e-245 852.4 Lactobacillaceae celB GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264,GO:1902815 ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 iECABU_c1320.ECABU_c19930 Bacteria 1TP8D@1239,3F4VG@33958,4H9W2@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane GOKNOHPG_01573 405566.lhv_0650 6e-206 723.4 Lactobacillaceae yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TQ9R@1239,3F4K8@33958,4HANR@91061,COG0513@1,COG0513@2 NA|NA|NA L DEAD DEAH box helicase GOKNOHPG_01574 405566.lhv_0649 7.5e-129 466.5 Lactobacillaceae ko:K07273 ko00000 Bacteria 1V484@1239,3F4K0@33958,4HQWA@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 GOKNOHPG_01575 326425.lhe_0578 6.7e-12 75.5 Lactobacillaceae potE ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ48@1239,3F3YJ@33958,4HBGT@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid GOKNOHPG_01576 326425.lhe_0578 6.5e-202 709.9 Lactobacillaceae potE ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ48@1239,3F3YJ@33958,4HBGT@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid GOKNOHPG_01577 326425.lhe_0577 5.4e-101 373.6 Lactobacillaceae hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 Bacteria 1V1C9@1239,3F56C@33958,4HFZ2@91061,COG0634@1,COG0634@2 NA|NA|NA F Belongs to the purine pyrimidine phosphoribosyltransferase family GOKNOHPG_01578 405566.lhv_0645 1.3e-238 832.0 Lactobacillaceae yhdP ko:K03699,ko:K06189 ko00000,ko02000,ko02042 9.A.40.1.2 Bacteria 1TPN0@1239,3F3TX@33958,4H9SB@91061,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain GOKNOHPG_01579 1423748.BALB01000004_gene580 1.7e-23 114.4 Lactobacillaceae Bacteria 1V6AG@1239,3F6YM@33958,4HN5N@91061,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase GOKNOHPG_01580 1423748.BALB01000004_gene580 2.7e-17 93.6 Lactobacillaceae Bacteria 1V6AG@1239,3F6YM@33958,4HN5N@91061,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase GOKNOHPG_01581 405566.lhv_2311 2.9e-36 157.5 Lactobacillaceae Bacteria 1U6H9@1239,29PEW@1,30AD2@2,3F7X8@33958,4IG9K@91061 NA|NA|NA GOKNOHPG_01582 405566.lhv_0640 1.9e-83 315.1 Lactobacillaceae pts23A ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1 Bacteria 1VAEB@1239,3FC0X@33958,4HIPR@91061,COG2190@1,COG2190@2 NA|NA|NA G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 GOKNOHPG_01583 1423748.BALB01000004_gene578 2.9e-74 284.6 Lactobacillaceae Bacteria 1U5P7@1239,2CJCY@1,309TS@2,3F69B@33958,4IFDR@91061 NA|NA|NA GOKNOHPG_01584 1423748.BALB01000004_gene577 6.5e-23 112.5 Lactobacillaceae glvR ko:K03481 ko00000,ko03000 Bacteria 1V2J8@1239,3FBJH@33958,4IQVX@91061,COG1737@1,COG1737@2 NA|NA|NA K Helix-turn-helix domain, rpiR family GOKNOHPG_01585 1423748.BALB01000004_gene577 5.2e-70 270.4 Lactobacillaceae glvR ko:K03481 ko00000,ko03000 Bacteria 1V2J8@1239,3FBJH@33958,4IQVX@91061,COG1737@1,COG1737@2 NA|NA|NA K Helix-turn-helix domain, rpiR family GOKNOHPG_01586 1423748.BALB01000004_gene576 1.2e-308 1065.1 Lactobacillaceae glvC 2.7.1.199,2.7.1.208 ko:K02749,ko:K02750,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 M00266,M00268 R02738,R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.10,4.A.1.1.16,4.A.1.1.3,4.A.1.1.4,4.A.1.1.8 Bacteria 1TPJ8@1239,3F44V@33958,4HA8X@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2 NA|NA|NA G phosphotransferase system, EIIB GOKNOHPG_01587 1423748.BALB01000004_gene576 8.3e-20 102.1 Lactobacillaceae glvC 2.7.1.199,2.7.1.208 ko:K02749,ko:K02750,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 M00266,M00268 R02738,R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.10,4.A.1.1.16,4.A.1.1.3,4.A.1.1.4,4.A.1.1.8 Bacteria 1TPJ8@1239,3F44V@33958,4HA8X@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2 NA|NA|NA G phosphotransferase system, EIIB GOKNOHPG_01588 525365.HMPREF0548_0642 1.6e-135 488.8 Lactobacillaceae Bacteria 1TR16@1239,3F55S@33958,4HCZ6@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase GOKNOHPG_01589 1423754.BALY01000021_gene892 1.2e-187 662.9 Lactobacillaceae Bacteria 1TSRV@1239,3F46B@33958,4HCIZ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC-type multidrug transport system, ATPase and permease components GOKNOHPG_01590 272621.LBA0074 5.1e-149 534.6 Lactobacillaceae Bacteria 1TSRV@1239,3F514@33958,4HCIZ@91061,COG1132@1,COG1132@2 NA|NA|NA P ABC transporter GOKNOHPG_01591 405566.lhv_0631 9.6e-147 526.2 Lactobacillaceae rssA Bacteria 1TQ9W@1239,3F52H@33958,4HCHJ@91061,COG4667@1,COG4667@2 NA|NA|NA S Phospholipase, patatin family GOKNOHPG_01592 405566.lhv_0629 0.0 1650.6 Lactobacillaceae xfp 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 Bacteria 1TR23@1239,3F3TZ@33958,4HC2J@91061,COG3957@1,COG3957@2 NA|NA|NA G Phosphoketolase GOKNOHPG_01593 405566.lhv_0263 3.3e-95 354.4 Lactobacillaceae ko:K07493 ko00000 Bacteria 1TP4C@1239,3F4RA@33958,4HAXJ@91061,COG3328@1,COG3328@2 NA|NA|NA L Transposase GOKNOHPG_01594 525365.HMPREF0548_0637 6.6e-206 723.4 Lactobacillaceae mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 1TPT1@1239,3F49Y@33958,4HAEA@91061,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system GOKNOHPG_01595 525365.HMPREF0548_0637 2.4e-14 84.3 Lactobacillaceae mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 1TPT1@1239,3F49Y@33958,4HAEA@91061,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system GOKNOHPG_01596 525365.HMPREF0548_0636 7.6e-44 183.0 Lactobacillaceae yitW ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1V9YV@1239,3F7D5@33958,4HKC6@91061,COG2151@1,COG2151@2 NA|NA|NA S Iron-sulfur cluster assembly protein GOKNOHPG_01597 525365.HMPREF0548_0635 3.1e-267 927.2 Lactobacillaceae sufB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 ko:K07033,ko:K09014 ko00000 Bacteria 1TQ21@1239,3F44I@33958,4HA1Z@91061,COG0719@1,COG0719@2 NA|NA|NA O assembly protein SufB GOKNOHPG_01598 525365.HMPREF0548_0634 2.7e-66 258.1 Lactobacillaceae nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 ko:K04488 ko00000 Bacteria 1V3H9@1239,3F6WP@33958,4HIJ0@91061,COG0822@1,COG0822@2 NA|NA|NA C SUF system FeS assembly protein, NifU family GOKNOHPG_01599 405566.lhv_0623 1.6e-206 725.3 Lactobacillaceae sufS 2.8.1.7,4.4.1.16 ko:K04487,ko:K11717 ko00450,ko00730,ko01100,ko04122,map00450,map00730,map01100,map04122 R03599,R07460,R11528,R11529 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TQ1W@1239,3F3UP@33958,4HA6Z@91061,COG0520@1,COG0520@2 NA|NA|NA E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine GOKNOHPG_01600 525365.HMPREF0548_0632 2.5e-199 701.4 Lactobacillaceae sufD ko:K07033,ko:K09015 ko00000 Bacteria 1TRT0@1239,3F4BR@33958,4HB6W@91061,COG0719@1,COG0719@2 NA|NA|NA O FeS assembly protein SufD GOKNOHPG_01601 405566.lhv_0621 8.7e-142 509.6 Lactobacillaceae sufC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 ko:K09013 ko00000,ko02000 iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710 Bacteria 1TQ98@1239,3F3XT@33958,4HAD9@91061,COG0396@1,COG0396@2 NA|NA|NA O FeS assembly ATPase SufC GOKNOHPG_01602 405566.lhv_1190 2.6e-37 161.0 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3FCFA@33958,4HC8M@91061,COG2801@1,COG2801@2 NA|NA|NA L COG2963 Transposase and inactivated derivatives GOKNOHPG_01603 405566.lhv_1190 2.1e-31 141.4 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3FCFA@33958,4HC8M@91061,COG2801@1,COG2801@2 NA|NA|NA L COG2963 Transposase and inactivated derivatives GOKNOHPG_01604 525365.HMPREF0548_0618 9.9e-103 379.4 Lactobacillaceae pflC 1.97.1.4 ko:K04069 R04710 ko00000,ko01000 Bacteria 1TPK2@1239,3FC98@33958,4HD35@91061,COG1180@1,COG1180@2 NA|NA|NA O Radical SAM superfamily GOKNOHPG_01605 1423748.BALB01000004_gene563 2.8e-135 488.0 Lactobacillaceae Bacteria 1V2JE@1239,3F3Z7@33958,4HWAW@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase GOKNOHPG_01606 1423748.BALB01000004_gene561 4e-133 480.7 Lactobacillaceae gntR ko:K03710 ko00000,ko03000 Bacteria 1TTCD@1239,3F4DA@33958,4HEXQ@91061,COG2188@1,COG2188@2 NA|NA|NA K UbiC transcription regulator-associated domain protein GOKNOHPG_01607 405566.lhv_0614 2.4e-175 621.3 Lactobacillaceae rihB 3.2.2.1 ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 Bacteria 1TSSS@1239,3F4T0@33958,4HB17@91061,COG1957@1,COG1957@2 NA|NA|NA F Nucleoside GOKNOHPG_01608 405566.lhv_0613 0.0 1277.7 Lactobacillaceae kup GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 ko:K03549 ko00000,ko02000 2.A.72 Bacteria 1TRUQ@1239,3F4CU@33958,4HA8Z@91061,COG3158@1,COG3158@2 NA|NA|NA P Transport of potassium into the cell GOKNOHPG_01610 525365.HMPREF0548_1209 1.6e-100 372.5 Lactobacillaceae mta ko:K11923 ko00000,ko03000 Bacteria 1TS86@1239,3F6G4@33958,4HJAU@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance GOKNOHPG_01611 326425.lhe_1031 1.6e-91 342.0 Lactobacillaceae yyaR ko:K06889 ko00000 Bacteria 1V6YX@1239,3F6BG@33958,4IQXU@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain GOKNOHPG_01612 405566.lhv_1132 0.0 1653.3 Lactobacillaceae uvrA3 ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TP0A@1239,3F3V4@33958,4HTDZ@91061,COG0178@1,COG0178@2 NA|NA|NA L excinuclease ABC, A subunit GOKNOHPG_01614 326425.lhe_1035 1e-55 222.6 Lactobacillaceae rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 1U7FQ@1239,3F9JR@33958,4IHBR@91061,COG0127@1,COG0127@2 NA|NA|NA F Ham1 family GOKNOHPG_01615 326425.lhe_1036 3.1e-72 277.7 Lactobacillaceae Bacteria 1VD10@1239,3F6QC@33958,4HMF3@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain GOKNOHPG_01616 326425.lhe_1037 2.5e-74 284.6 Lactobacillaceae Bacteria 1U66T@1239,2A0WQ@1,30P1T@2,3F77R@33958,4IFX9@91061 NA|NA|NA S Protein of unknown function (DUF3021) GOKNOHPG_01617 405566.lhv_1134 0.0 1193.3 Lactobacillaceae mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TQWB@1239,3F47G@33958,4HAHW@91061,COG1193@1,COG1193@2 NA|NA|NA L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity GOKNOHPG_01619 405566.lhv_1136 4.2e-286 989.9 Lactobacillaceae lsa ko:K06158,ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000,ko03012 3.A.1.121 Bacteria 1TNYS@1239,3F53D@33958,4HBFK@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter GOKNOHPG_01621 1033837.WANG_1094 1.1e-276 958.7 Lactobacillaceae Bacteria 1U7ZF@1239,29QEQ@1,30BE2@2,3FACR@33958,4IHWS@91061 NA|NA|NA GOKNOHPG_01622 1033837.WANG_p1062 1.4e-115 422.2 Lactobacillaceae ko:K04763 ko00000,ko03036 Bacteria 1V2RX@1239,3F4SP@33958,4IEJ7@91061,COG0582@1,COG0582@2 NA|NA|NA L Integrase GOKNOHPG_01623 1033837.WANG_p1061 4.2e-223 780.4 Bacilli Bacteria 1UZSK@1239,4HVI6@91061,COG1996@1,COG1996@2 NA|NA|NA K Probable Zinc-ribbon domain GOKNOHPG_01624 1033837.WANG_1664 2.8e-44 184.9 Lactobacillaceae glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1UGF1@1239,3FC1C@33958,4HBM4@91061,COG0584@1,COG0584@2,COG4781@1,COG4781@2 NA|NA|NA C Membrane domain of glycerophosphoryl diester phosphodiesterase GOKNOHPG_01625 326425.lhe_0123 5.6e-68 263.5 Lactobacillaceae Bacteria 1VY7K@1239,2F916@1,341CT@2,3F70S@33958,4HX4B@91061 NA|NA|NA S Iron-sulphur cluster biosynthesis GOKNOHPG_01626 405566.lhv_0110 1.4e-190 672.2 Lactobacillaceae ybiR GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1TQCH@1239,3F4CJ@33958,4HEW7@91061,COG1055@1,COG1055@2 NA|NA|NA P Citrate transporter GOKNOHPG_01627 405566.lhv_0109 8.7e-96 356.3 Lactobacillaceae lemA ko:K03744 ko00000 Bacteria 1V4SV@1239,3FBKP@33958,4IR1I@91061,COG1704@1,COG1704@2 NA|NA|NA S LemA family GOKNOHPG_01628 405566.lhv_0108 1.5e-161 575.5 Lactobacillaceae htpX ko:K03799 M00743 ko00000,ko00002,ko01000,ko01002 Bacteria 1TP23@1239,3F40Z@33958,4HB11@91061,COG0501@1,COG0501@2 NA|NA|NA O Belongs to the peptidase M48B family GOKNOHPG_01629 1423754.BALY01000006_gene1343 1.6e-41 175.3 Lactobacillaceae ko:K07483 ko00000 Bacteria 1V1QC@1239,3F65F@33958,4HH7E@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain GOKNOHPG_01630 1423754.BALY01000006_gene1343 1.3e-49 202.2 Lactobacillaceae ko:K07483 ko00000 Bacteria 1V1QC@1239,3F65F@33958,4HH7E@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain GOKNOHPG_01631 1423754.BALY01000006_gene1344 4.5e-166 590.5 Lactobacillaceae Bacteria 1TQEG@1239,3F43M@33958,4HD6M@91061,COG2801@1,COG2801@2 NA|NA|NA L hmm pf00665 GOKNOHPG_01632 405566.lhv_0105 2.5e-172 611.3 Lactobacillaceae Bacteria 1VCUV@1239,3F48T@33958,4HGUV@91061,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein GOKNOHPG_01633 326425.lhe_0117 9.3e-245 852.4 Lactobacillaceae cbiO1 ko:K05776,ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00189,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1UI2R@1239,3F3WM@33958,4ISG8@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein GOKNOHPG_01634 1423748.BALB01000006_gene819 3.4e-91 341.3 Lactobacillaceae ko:K16785 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1V2VE@1239,3FBE3@33958,4IPQA@91061,COG0619@1,COG0619@2 NA|NA|NA P Cobalt transport protein GOKNOHPG_01635 405566.lhv_0102 7.4e-174 616.3 Lactobacillaceae pepI 3.4.11.5,3.5.1.101 ko:K01259,ko:K18457 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 1TRMT@1239,3F40N@33958,4HE23@91061,COG2267@1,COG2267@2 NA|NA|NA E Releases the N-terminal proline from various substrates GOKNOHPG_01636 326425.lhe_1822 3.1e-75 288.9 Lactobacillaceae Bacteria 1U5FB@1239,2DKJ8@1,309P7@2,3F5UP@33958,4IF6X@91061 NA|NA|NA S SLAP domain GOKNOHPG_01637 585524.HMPREF0493_1138 1.9e-98 365.9 Lactobacillaceae Bacteria 1U53C@1239,29NJD@1,309H9@2,3F4BP@33958,4IEUN@91061 NA|NA|NA S Bacteriocin helveticin-J GOKNOHPG_01638 1203076.CAKF01000010_gene269 3.5e-60 238.0 Lactobacillaceae apt 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 Bacteria 1V1XS@1239,3F6EK@33958,4HG1T@91061,COG0503@1,COG0503@2 NA|NA|NA F Phosphoribosyl transferase domain GOKNOHPG_01639 944562.HMPREF9102_1853 2.8e-151 541.6 Lactobacillaceae ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 1UY33@1239,3F41X@33958,4HDN5@91061,COG0659@1,COG0659@2 NA|NA|NA P secondary active sulfate transmembrane transporter activity GOKNOHPG_01640 405566.lhv_1420 3.4e-68 264.2 Lactobacillaceae yqhY ko:K10947 ko00000,ko03000 Bacteria 1V4IC@1239,3F71X@33958,4HJ7T@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function GOKNOHPG_01641 1423748.BALB01000011_gene1167 1.2e-100 372.5 Lactobacillaceae efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 1TR8P@1239,3F422@33958,4H9YX@91061,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase GOKNOHPG_01642 405566.lhv_1422 5.4e-198 696.8 Lactobacillaceae pepP 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 ko00000,ko01000,ko01002 Bacteria 1TQ44@1239,3F4DR@33958,4HAT7@91061,COG0006@1,COG0006@2 NA|NA|NA E Creatinase/Prolidase N-terminal domain GOKNOHPG_01643 1423748.BALB01000011_gene1169 1e-47 195.7 Lactobacillaceae rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6HW@1239,3F6WU@33958,4HIMN@91061,COG0211@1,COG0211@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL27 family GOKNOHPG_01644 1423748.BALB01000011_gene1170 5.8e-49 199.9 Lactobacillaceae rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9YH@1239,3F6WT@33958,4HIGK@91061,COG0261@1,COG0261@2 NA|NA|NA J This protein binds to 23S rRNA in the presence of protein L20 GOKNOHPG_01645 326425.lhe_1345 8.5e-254 882.5 Lactobacillaceae Bacteria 1VK4A@1239,2EM25@1,33ERN@2,3F53P@33958,4HRGD@91061 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2325) GOKNOHPG_01646 326425.lhe_1346 5.3e-200 703.4 Lactobacillaceae ilvE 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TQQI@1239,3F4BD@33958,4HASX@91061,COG0115@1,COG0115@2 NA|NA|NA E Branched-chain amino acid aminotransferase GOKNOHPG_01647 326425.lhe_1347 6.1e-128 463.4 Lactobacillaceae Bacteria 1VBTT@1239,2E7EK@1,331XM@2,3F4W0@33958,4HMT5@91061 NA|NA|NA S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) GOKNOHPG_01648 1033837.WANG_0371 2.1e-27 127.5 Lactobacillaceae dmpI GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 Bacteria 1VKD5@1239,3F83T@33958,4HRBS@91061,COG1942@1,COG1942@2 NA|NA|NA G Belongs to the 4-oxalocrotonate tautomerase family GOKNOHPG_01649 405566.lhv_1432 0.0 1084.7 Lactobacillaceae Bacteria 1TS3Q@1239,3F4AT@33958,4HF7D@91061,COG4907@1,COG4907@2 NA|NA|NA S Predicted membrane protein (DUF2207) GOKNOHPG_01650 405566.lhv_1433 2.3e-170 605.1 Lactobacillaceae ko:K07273 ko00000 Bacteria 1VF8D@1239,3F4U9@33958,4HX0U@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 GOKNOHPG_01652 326425.lhe_1352 1.6e-51 208.4 Lactobacillaceae Bacteria 1V2AW@1239,3F3N7@33958,4HU2V@91061,COG0657@1,COG0657@2 NA|NA|NA I Carboxylesterase family GOKNOHPG_01653 326425.lhe_1352 1.6e-114 418.7 Lactobacillaceae Bacteria 1V2AW@1239,3F3N7@33958,4HU2V@91061,COG0657@1,COG0657@2 NA|NA|NA I Carboxylesterase family GOKNOHPG_01654 405566.lhv_1435 1.1e-64 252.3 Lactobacillaceae arsC 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1VA5Q@1239,3F72U@33958,4HKQQ@91061,COG1393@1,COG1393@2 NA|NA|NA P Belongs to the ArsC family GOKNOHPG_01655 748671.LCRIS_01361 1.5e-26 125.2 Lactobacillaceae Bacteria 1U6JT@1239,2DKR3@1,30AEW@2,3F81U@33958,4IGCA@91061 NA|NA|NA GOKNOHPG_01656 525365.HMPREF0548_0800 1.1e-59 236.5 Lactobacillaceae Bacteria 1VMSZ@1239,2DF54@1,32U4N@2,3F6U1@33958,4HSRG@91061 NA|NA|NA S Bacterial PH domain GOKNOHPG_01657 405566.lhv_1436 0.0 1575.8 Lactobacillaceae pepX 3.4.14.11 ko:K01281 ko00000,ko01000,ko01002 Bacteria 1TT78@1239,3FCF2@33958,4IRQ0@91061,COG2936@1,COG2936@2 NA|NA|NA E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline GOKNOHPG_01658 405566.lhv_0016 0.0 1275.4 Lactobacillaceae yybT Bacteria 1TPGP@1239,3F3TY@33958,4HBVH@91061,COG3887@1,COG3887@2 NA|NA|NA T signaling protein consisting of a modified GGDEF domain and a DHH domain GOKNOHPG_01659 1423748.BALB01000029_gene1873 1.1e-67 262.7 Lactobacillaceae rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6QG@1239,3F68P@33958,4HIKJ@91061,COG0359@1,COG0359@2 NA|NA|NA J Binds to the 23S rRNA GOKNOHPG_01660 1423748.BALB01000029_gene1874 2.5e-253 880.9 Lactobacillaceae dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 1TPCT@1239,3F4MW@33958,4H9Y8@91061,COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication GOKNOHPG_01661 405566.lhv_0019 1.5e-164 585.5 Lactobacillaceae phnD ko:K02044 ko02010,map02010 M00223 ko00000,ko00001,ko00002,ko02000 3.A.1.9 Bacteria 1TR0H@1239,3FB6H@33958,4HBU5@91061,COG3221@1,COG3221@2 NA|NA|NA P ABC transporter, phosphonate, periplasmic substrate-binding protein GOKNOHPG_01662 405566.lhv_0021 6.6e-173 613.2 Lactobacillaceae degV Bacteria 1V289@1239,3F4D9@33958,4I3AR@91061,COG1307@1,COG1307@2 NA|NA|NA S DegV family GOKNOHPG_01663 326425.lhe_0025 1.9e-43 181.4 Lactobacillaceae scrK 2.7.1.2,2.7.1.4 ko:K00845,ko:K00847 ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R00760,R00867,R01600,R01786,R03920 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQU4@1239,3F3K8@33958,4HA1C@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family GOKNOHPG_01664 405566.lhv_1956 8.7e-125 453.0 Lactobacillaceae ko:K16924,ko:K16927 M00582 ko00000,ko00002,ko02000 3.A.1.29,3.A.1.32 Bacteria 1V2DR@1239,3F4W4@33958,4HFXY@91061,COG4720@1,COG4720@2 NA|NA|NA S ECF-type riboflavin transporter, S component GOKNOHPG_01665 405566.lhv_1955 1.2e-310 1071.6 Lactobacillaceae ykoD_2 ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1UI2B@1239,3FBVX@33958,4ISBR@91061,COG3845@1,COG3845@2 NA|NA|NA S AAA domain, putative AbiEii toxin, Type IV TA system GOKNOHPG_01666 1033837.WANG_1513 4.3e-153 547.4 Lactobacillaceae ko:K16785 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TSB5@1239,3F5CF@33958,4HDM2@91061,COG0619@1,COG0619@2 NA|NA|NA P ABC-type cobalt transport system permease component CbiQ and related transporters GOKNOHPG_01667 1033837.WANG_0664 6.2e-25 119.4 Lactobacillaceae Bacteria 1UZVH@1239,2BVJW@1,32QXP@2,3F54U@33958,4HFK6@91061 NA|NA|NA S Uncharacterised protein family (UPF0236) GOKNOHPG_01668 1033837.WANG_1500 1.3e-118 433.3 Lactobacillaceae ko:K21449 ko00000,ko02000 1.B.40.2 Bacteria 1VQKC@1239,2EGNI@1,33AEP@2,3F4VE@33958,4HP40@91061 NA|NA|NA S Domain of unknown function (DUF4430) GOKNOHPG_01669 1033837.WANG_1501 1.8e-179 635.2 Lactobacillaceae Bacteria 1W217@1239,3F596@33958,4I1VH@91061,COG5066@1,COG5066@2 NA|NA|NA U FFAT motif binding GOKNOHPG_01670 405566.lhv_1948 3.3e-74 285.0 Lactobacillaceae Bacteria 1U6HF@1239,2EGNI@1,33AEP@2,3F7XJ@33958,4IG9S@91061 NA|NA|NA S Domain of unknown function (DUF4430) GOKNOHPG_01671 1437605.BACT_1132 1.4e-30 139.0 Bifidobacteriales bcgIB 2.1.1.72,3.1.21.3 ko:K01154,ko:K03427 ko00000,ko01000,ko02048 Bacteria 2IPXW@201174,4D0XX@85004,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain GOKNOHPG_01672 326425.lhe_1458 1.5e-169 602.1 Lactobacillaceae 2.7.1.59 ko:K00884 ko00520,ko01100,map00520,map01100 R01201 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1V38W@1239,3F5MG@33958,4HGPI@91061,COG2971@1,COG2971@2 NA|NA|NA G BadF/BadG/BcrA/BcrD ATPase family GOKNOHPG_01673 405566.lhv_1571 0.0 1640.6 Lactobacillaceae Bacteria 1TRR1@1239,3F49G@33958,4HBW6@91061,COG4485@1,COG4485@2 NA|NA|NA S membrane GOKNOHPG_01674 326425.lhe_1456 0.0 1357.8 Lactobacillaceae pbp2b 3.4.16.4 ko:K00687,ko:K05515,ko:K12553,ko:K21465 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Bacteria 1TQHY@1239,3F3KH@33958,4HAFX@91061,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein GOKNOHPG_01675 1423748.BALB01000003_gene424 1.2e-20 104.8 Lactobacillaceae rpmG ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEJ4@1239,3F828@33958,4HNIM@91061,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family GOKNOHPG_01676 326425.lhe_1454 1.6e-97 362.1 Lactobacillaceae ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 Bacteria 1VA91@1239,3FC8W@33958,4HKQI@91061,COG0212@1,COG0212@2 NA|NA|NA H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family GOKNOHPG_01677 405566.lhv_1567 3.5e-115 421.0 Lactobacillaceae gluP 3.4.21.105 ko:K19225 ko00000,ko01000,ko01002 Bacteria 1TQXT@1239,3FC8V@33958,4HCDF@91061,COG0705@1,COG0705@2 NA|NA|NA S Rhomboid family GOKNOHPG_01678 1423748.BALB01000003_gene427 1.2e-32 145.2 Lactobacillaceae yqgQ Bacteria 1VK83@1239,3F83I@33958,4HRG2@91061,COG4483@1,COG4483@2 NA|NA|NA S Bacterial protein of unknown function (DUF910) GOKNOHPG_01679 405566.lhv_1565 5e-69 266.9 Lactobacillaceae yqhL Bacteria 1VAI7@1239,3F67E@33958,4HKCE@91061,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese-like protein GOKNOHPG_01680 326425.lhe_1450 1.3e-168 599.0 Lactobacillaceae miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 1TPSC@1239,3F3XS@33958,4HAVW@91061,COG0324@1,COG0324@2 NA|NA|NA F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) GOKNOHPG_01681 1423748.BALB01000003_gene430 8.5e-36 156.0 Lactobacillaceae ynbB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 4.4.1.1 ko:K01758 ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230 M00338 R00782,R01001,R02408,R04770,R04930,R09366 RC00056,RC00069,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TQ88@1239,3F3PU@33958,4HAF5@91061,COG4100@1,COG4100@2 NA|NA|NA P aluminum resistance GOKNOHPG_01682 1423748.BALB01000003_gene430 4.6e-82 310.5 Lactobacillaceae ynbB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 4.4.1.1 ko:K01758 ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230 M00338 R00782,R01001,R02408,R04770,R04930,R09366 RC00056,RC00069,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TQ88@1239,3F3PU@33958,4HAF5@91061,COG4100@1,COG4100@2 NA|NA|NA P aluminum resistance GOKNOHPG_01683 326425.lhe_1448 2.9e-262 910.6 Lactobacillaceae glnA 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 1TNZA@1239,3F41A@33958,4HACE@91061,COG0174@1,COG0174@2 NA|NA|NA E glutamine synthetase GOKNOHPG_01684 326425.lhe_1447 2.4e-132 478.4 Lactobacillaceae Bacteria 1U5CK@1239,2ACE2@1,311ZJ@2,3F5IZ@33958,4IF3R@91061 NA|NA|NA GOKNOHPG_01685 405566.lhv_1556 5.1e-162 577.0 Lactobacillaceae Bacteria 1U54Z@1239,2ACE2@1,309I3@2,3F4PW@33958,4IEW5@91061 NA|NA|NA GOKNOHPG_01686 326425.lhe_1445 2.7e-148 531.6 Lactobacillaceae Bacteria 1U5E7@1239,2ACE2@1,309NT@2,3F5PN@33958,4IF5H@91061 NA|NA|NA GOKNOHPG_01687 326425.lhe_0806 4.1e-26 123.2 Lactobacillaceae Bacteria 1U6G3@1239,29PDV@1,30AC1@2,3F7U6@33958,4IG84@91061 NA|NA|NA GOKNOHPG_01688 326425.lhe_0805 1.6e-288 998.0 Lactobacillaceae ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1V08F@1239,3F517@33958,4HTAU@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region GOKNOHPG_01689 326425.lhe_0804 4.4e-104 384.0 Lactobacillaceae Bacteria 1U6TT@1239,3F8H4@33958,4IGMM@91061,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase GOKNOHPG_01690 1423748.BALB01000001_gene66 1.1e-142 512.7 Lactobacillaceae Bacteria 1U53D@1239,29NJE@1,309HA@2,3F4BT@33958,4IEUP@91061 NA|NA|NA K Helix-turn-helix XRE-family like proteins GOKNOHPG_01691 97137.C821_01019 8e-23 113.6 Lactobacillaceae Bacteria 1U60J@1239,29NJE@1,30A05@2,3F6SJ@33958,4IFPC@91061 NA|NA|NA K Helix-turn-helix XRE-family like proteins GOKNOHPG_01692 1423748.BALB01000001_gene75 9.3e-45 186.0 Lactobacillaceae Bacteria 1U7MU@1239,29NJE@1,30B6P@2,3F9XA@33958,4IHJ3@91061 NA|NA|NA GOKNOHPG_01693 1423748.BALB01000001_gene76 2e-14 84.7 Lactobacillaceae Bacteria 1U81Y@1239,29NJE@1,30KQC@2,3FAFF@33958,4IHZB@91061 NA|NA|NA K Helix-turn-helix XRE-family like proteins GOKNOHPG_01694 1033837.WANG_0872 2.5e-124 451.4 Lactobacillaceae rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 ko00000,ko01000,ko03009 Bacteria 1TQZ2@1239,3F41G@33958,4H9VU@91061,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family GOKNOHPG_01695 1423748.BALB01000001_gene78 1.3e-143 515.8 Lactobacillaceae Bacteria 1U6CJ@1239,29NJE@1,30A94@2,3F7KV@33958,4IG48@91061 NA|NA|NA K Helix-turn-helix domain GOKNOHPG_01696 405566.lhv_0823 7.2e-228 796.2 Lactobacillaceae thiI GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07461 ko00000,ko00001,ko01000,ko03016 iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307 Bacteria 1TPNW@1239,3F3N0@33958,4HAV9@91061,COG0301@1,COG0301@2 NA|NA|NA H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS GOKNOHPG_01697 405566.lhv_0822 2.7e-216 757.7 Lactobacillaceae iscS2 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TP21@1239,3F4CD@33958,4HAEE@91061,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class V GOKNOHPG_01698 326425.lhe_0793 1.7e-280 971.5 Lactobacillaceae ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 ko:K06286,ko:K07158 ko00000,ko03036 Bacteria 1TQR7@1239,3F47K@33958,4HA15@91061,COG4477@1,COG4477@2 NA|NA|NA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization GOKNOHPG_01699 326425.lhe_0792 8.9e-110 402.9 Lactobacillaceae rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 ko:K02986 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TR0J@1239,3F3P0@33958,4HAC9@91061,COG0522@1,COG0522@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit GOKNOHPG_01700 326425.lhe_0791 6.6e-81 306.6 Lactobacillaceae yueI Bacteria 1V8ID@1239,3FCEV@33958,4HJTQ@91061,COG5506@1,COG5506@2 NA|NA|NA S Protein of unknown function (DUF1694) GOKNOHPG_01701 405566.lhv_0818 3.6e-241 840.5 Lactobacillaceae rarA ko:K07478 ko00000 Bacteria 1TPVV@1239,3F3WF@33958,4HAIS@91061,COG2256@1,COG2256@2 NA|NA|NA L recombination factor protein RarA GOKNOHPG_01702 405566.lhv_2404 1.6e-34 151.8 Lactobacillaceae Bacteria 1U6AF@1239,29P9A@1,30A7E@2,3F7FU@33958,4IG1T@91061 NA|NA|NA GOKNOHPG_01703 405566.lhv_0527 3.4e-95 354.4 Lactobacillaceae glpQ1 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1V3W4@1239,3F4E3@33958,4HFNQ@91061,COG0584@1,COG0584@2 NA|NA|NA C glycerophosphoryl diester phosphodiesterase GOKNOHPG_01704 326425.lhe_0524 6.2e-117 426.8 Lactobacillaceae VY92_08690 5.3.1.32 ko:K11530 ko02024,map02024 ko00000,ko00001,ko01000 Bacteria 1VVR5@1239,3F5NS@33958,4HWFJ@91061,COG0406@1,COG0406@2,COG1359@1,COG1359@2 NA|NA|NA G Antibiotic biosynthesis monooxygenase GOKNOHPG_01705 1423748.BALB01000016_gene1450 1.5e-101 375.6 Lactobacillaceae Bacteria 1V4Y8@1239,3F5FJ@33958,4IF2Q@91061,COG0406@1,COG0406@2 NA|NA|NA G Histidine phosphatase superfamily (branch 1) GOKNOHPG_01706 1033837.WANG_1161 4.9e-110 403.7 Lactobacillaceae Bacteria 1UXY8@1239,3F4JB@33958,4HFD9@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family GOKNOHPG_01707 1033837.WANG_1162 4.4e-197 693.7 Lactobacillaceae Bacteria 1U570@1239,3F4ZJ@33958,4IEYI@91061,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation GOKNOHPG_01708 405566.lhv_0523 4.4e-57 228.0 Lactobacillaceae Bacteria 1V773@1239,3F3JQ@33958,4HIJG@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain protein GOKNOHPG_01709 1033837.WANG_1164 1.2e-158 565.8 Lactobacillaceae Bacteria 1TPCZ@1239,3F4I6@33958,4HC7A@91061,COG0826@1,COG0826@2 NA|NA|NA O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity GOKNOHPG_01710 525365.HMPREF0548_0526 7.5e-84 316.6 Lactobacillaceae celB ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 iYO844.BSU38390 Bacteria 1TP8D@1239,3F3Q4@33958,4H9W2@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane GOKNOHPG_01711 272621.LBA0491 4.7e-95 354.0 Lactobacillaceae celB ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 iYO844.BSU38390 Bacteria 1TP8D@1239,3F3Q4@33958,4H9W2@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane GOKNOHPG_01712 1033837.WANG_1165 9.6e-13 78.2 Lactobacillaceae Bacteria 1U6Y4@1239,29PR7@1,30APF@2,3F8PS@33958,4IGSA@91061 NA|NA|NA GOKNOHPG_01713 1033837.WANG_1166 3.4e-26 123.6 Lactobacillaceae ko:K06921 ko00000 Bacteria 1TR21@1239,3F57U@33958,4HF7F@91061,COG1672@1,COG1672@2 NA|NA|NA S Archaea bacterial proteins of unknown function GOKNOHPG_01714 1033837.WANG_1166 2.8e-224 784.3 Lactobacillaceae ko:K06921 ko00000 Bacteria 1TR21@1239,3F57U@33958,4HF7F@91061,COG1672@1,COG1672@2 NA|NA|NA S Archaea bacterial proteins of unknown function GOKNOHPG_01715 1033837.WANG_1167 1.4e-169 602.1 Lactobacillaceae pphA 3.1.3.16 ko:K01090,ko:K07313 ko00000,ko01000 Bacteria 1V1HN@1239,3F401@33958,4HF40@91061,COG0639@1,COG0639@2 NA|NA|NA T Calcineurin-like phosphoesterase GOKNOHPG_01716 1033837.WANG_1168 7.3e-63 246.5 Lactobacillaceae Bacteria 1U643@1239,2C7EH@1,30A2S@2,3F6ZP@33958,4IFTN@91061 NA|NA|NA GOKNOHPG_01717 1033837.WANG_1169 1.2e-11 74.3 Lactobacillaceae Bacteria 1U6T5@1239,2C7HR@1,30AK4@2,3F8FZ@33958,4IGKW@91061 NA|NA|NA GOKNOHPG_01718 1033837.WANG_1170 5e-69 266.9 Lactobacillaceae Bacteria 1U5KS@1239,2F916@1,309SE@2,3F65Y@33958,4IFBR@91061 NA|NA|NA S Iron-sulphur cluster biosynthesis GOKNOHPG_01719 1033837.WANG_1171 4.6e-28 129.8 Lactobacillaceae Bacteria 1V4U7@1239,3F5H8@33958,4HHGF@91061,COG4185@1,COG4185@2 NA|NA|NA S protein conserved in bacteria GOKNOHPG_01720 1033837.WANG_1171 2.9e-29 134.0 Lactobacillaceae Bacteria 1V4U7@1239,3F5H8@33958,4HHGF@91061,COG4185@1,COG4185@2 NA|NA|NA S protein conserved in bacteria GOKNOHPG_01721 1033837.WANG_1171 1.2e-17 94.7 Lactobacillaceae Bacteria 1V4U7@1239,3F5H8@33958,4HHGF@91061,COG4185@1,COG4185@2 NA|NA|NA S protein conserved in bacteria GOKNOHPG_01723 1033837.WANG_1173 8.4e-56 223.0 Lactobacillaceae psiE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K13256 ko00000 Bacteria 1VCG5@1239,3FBQN@33958,4HKQN@91061,COG3223@1,COG3223@2 NA|NA|NA S Phosphate-starvation-inducible E GOKNOHPG_01724 1033837.WANG_1533 1.9e-195 688.3 Lactobacillaceae Bacteria 1TQQ0@1239,3F4D3@33958,4HDKW@91061,COG1228@1,COG1228@2 NA|NA|NA Q Imidazolonepropionase and related amidohydrolases GOKNOHPG_01725 1291743.LOSG293_220360 8.7e-124 450.3 Lactobacillaceae repA Bacteria 1VHQA@1239,2DP1C@1,3304N@2,3F55E@33958,4HPY6@91061 NA|NA|NA S Replication initiator protein A GOKNOHPG_01726 1423807.BACO01000054_gene1616 7.1e-99 367.1 Lactobacillaceae soj ko:K03496 ko00000,ko03036,ko04812 Bacteria 1TP8S@1239,3F4QA@33958,4HCBZ@91061,COG1192@1,COG1192@2 NA|NA|NA D CobQ CobB MinD ParA nucleotide binding domain protein GOKNOHPG_01727 1154757.Q5C_08115 3.3e-16 91.3 Leuconostocaceae Bacteria 1U3M0@1239,2BVCH@1,32QSJ@2,4AYJ7@81850,4IDDI@91061 NA|NA|NA GOKNOHPG_01729 938293.CAJU020000009_gene1201 7.6e-09 65.9 Clostridia Bacteria 1TPFS@1239,249JM@186801,COG3039@1,COG3039@2 NA|NA|NA L PFAM transposase, IS4 family protein GOKNOHPG_01732 203123.OEOE_0169 1.1e-20 105.9 Leuconostocaceae mdtG GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085 ko:K08161 ko00000,ko02000 2.A.1.2.20 Bacteria 1TRDJ@1239,4AWJ1@81850,4H9Q9@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GOKNOHPG_01733 586413.CCDL010000001_gene561 5e-71 275.8 Bacilli ko:K06915 ko00000 Bacteria 1TPQN@1239,4HC61@91061,COG0433@1,COG0433@2 NA|NA|NA S cog cog0433 GOKNOHPG_01734 585203.SMSK564_1854 8.8e-35 154.8 Bacilli Bacteria 1VEF7@1239,2Z924@2,4HI26@91061,arCOG14100@1 NA|NA|NA S SIR2-like domain GOKNOHPG_01735 1114972.AUAW01000027_gene721 7.7e-76 289.7 Lactobacillaceae Bacteria 1U342@1239,3F5GC@33958,4IF2W@91061,COG3293@1,COG3293@2 NA|NA|NA L Transposase DDE domain GOKNOHPG_01738 748671.LCRIS_01032 2.4e-19 100.9 Lactobacillaceae rimL ko:K03817 ko00000,ko01000,ko03009 Bacteria 1V3NE@1239,3F6YW@33958,4HG1N@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain GOKNOHPG_01739 1423758.BN55_08785 1e-121 443.0 Lactobacillaceae 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1VA24@1239,3F4H4@33958,4IQXZ@91061,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family GOKNOHPG_01740 1423758.BN55_08805 4.2e-83 314.3 Lactobacillaceae XK27_07525 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1U7WX@1239,3F4BS@33958,4HHQT@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain GOKNOHPG_01742 1423748.BALB01000037_gene1992 8.1e-98 363.2 Lactobacillaceae Bacteria 1V3HS@1239,3F4HP@33958,4IQPW@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain GOKNOHPG_01743 326425.lhe_0090 6.7e-93 346.7 Lactobacillaceae Bacteria 1TRVX@1239,3F48I@33958,4HFSV@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator, LysR family GOKNOHPG_01744 405566.lhv_2203 2.7e-28 130.6 Firmicutes Bacteria 1V64Y@1239,COG4892@1,COG4892@2 NA|NA|NA S Cytochrome b5 GOKNOHPG_01745 326425.lhe_0091 7.1e-61 239.6 Lactobacillaceae arbZ Bacteria 1V2F4@1239,3F5FU@33958,4IF2T@91061,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases GOKNOHPG_01746 405566.lhv_0074 1.3e-88 332.4 Lactobacillaceae arbZ Bacteria 1V2F4@1239,3F5FU@33958,4IF2T@91061,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases GOKNOHPG_01747 525365.HMPREF0548_1834 2.5e-159 568.2 Lactobacillaceae arbY GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0016740,GO:0016757,GO:0043170,GO:0044238,GO:0071704,GO:1901576 Bacteria 1VGDI@1239,3FBE4@33958,4IPQC@91061,COG1442@1,COG1442@2 NA|NA|NA M Glycosyl transferase family 8 GOKNOHPG_01748 1423790.BN53_01200 3.3e-19 100.5 Lactobacillaceae Bacteria 1U7X4@1239,29DXA@1,30BCR@2,3FAA3@33958,4IHUG@91061 NA|NA|NA GOKNOHPG_01750 1423748.BALB01000006_gene832 2.7e-32 144.1 Lactobacillaceae Bacteria 1USWD@1239,2930D@1,3270J@2,3F7S4@33958,4IG6X@91061 NA|NA|NA GOKNOHPG_01752 405566.lhv_0095 2.2e-131 474.9 Lactobacillaceae Bacteria 1TPQG@1239,3F4FB@33958,4HA8Q@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator GOKNOHPG_01753 1423748.BALB01000006_gene829 1.4e-291 1008.4 Lactobacillaceae vicK 2.7.13.3 ko:K07652 ko02020,map02020 M00459 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQ1H@1239,3F45G@33958,4HA52@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase GOKNOHPG_01754 1423748.BALB01000006_gene828 1.2e-239 835.5 Lactobacillaceae yycH Bacteria 1V32Y@1239,3F4HR@33958,4HG2Q@91061,COG4863@1,COG4863@2 NA|NA|NA S YycH protein GOKNOHPG_01755 405566.lhv_0098 7.7e-149 533.1 Lactobacillaceae yycI Bacteria 1V1FW@1239,3F3PV@33958,4HFWZ@91061,COG4853@1,COG4853@2 NA|NA|NA S YycH protein GOKNOHPG_01756 405566.lhv_0099 2.4e-147 528.1 Lactobacillaceae vicX 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 1TQ8E@1239,3F3S4@33958,4HAKD@91061,COG1235@1,COG1235@2 NA|NA|NA S domain protein GOKNOHPG_01757 405566.lhv_0100 1.6e-206 725.3 Lactobacillaceae htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04691,ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1TRM8@1239,3F45X@33958,4HA31@91061,COG0265@1,COG0265@2 NA|NA|NA O serine protease GOKNOHPG_01758 1423748.BALB01000006_gene823 4.4e-89 334.0 Lactobacillaceae rlmH 2.1.1.177 ko:K00783 ko00000,ko01000,ko03009 Bacteria 1V3JM@1239,3F3YX@33958,4HFP8@91061,COG1576@1,COG1576@2 NA|NA|NA J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA GOKNOHPG_01759 1033837.WANG_0616 9.7e-283 978.8 Lactobacillaceae lsa ko:K06158,ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000,ko03012 3.A.1.121 Bacteria 1TNYS@1239,3F53D@33958,4HBFK@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter GOKNOHPG_01760 1033837.WANG_0615 2.8e-35 154.1 Lactobacillaceae Bacteria 1U797@1239,29PZQ@1,30AY5@2,3F957@33958,4IH43@91061 NA|NA|NA GOKNOHPG_01761 1033837.WANG_0614 6.5e-37 159.5 Lactobacillaceae Bacteria 1U797@1239,29PZQ@1,30AY5@2,3F957@33958,4IH43@91061 NA|NA|NA GOKNOHPG_01762 1033837.WANG_0613 1.9e-124 451.8 Lactobacillaceae Bacteria 1U5U0@1239,309W7@2,3F6I4@33958,4IFHY@91061,COG5585@1 NA|NA|NA GOKNOHPG_01763 1403313.AXBR01000023_gene2581 3.1e-14 85.1 Bacillus Bacteria 1VARJ@1239,1ZHPC@1386,2E58T@1,33017@2,4HKU9@91061 NA|NA|NA S Uncharacterised protein family (UPF0158) GOKNOHPG_01764 525365.HMPREF0548_0530 2.8e-40 171.0 Bacteria Bacteria COG1598@1,COG1598@2 NA|NA|NA N PFAM Uncharacterised protein family UPF0150 GOKNOHPG_01765 525365.HMPREF0548_0530 4.3e-09 66.2 Bacteria Bacteria COG1598@1,COG1598@2 NA|NA|NA N PFAM Uncharacterised protein family UPF0150 GOKNOHPG_01766 326425.lhe_1041 0.0 1189.9 Lactobacillaceae treB ko:K02755,ko:K02756,ko:K02757,ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system GOKNOHPG_01767 326425.lhe_1042 1.2e-129 469.2 Lactobacillaceae treR ko:K03486,ko:K03492,ko:K03710 ko00000,ko03000 Bacteria 1TRF6@1239,3F62J@33958,4HDCX@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA GOKNOHPG_01768 326425.lhe_1043 0.0 1136.7 Lactobacillaceae treC GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005991,GO:0005993,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008788,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0015927,GO:0016052,GO:0016787,GO:0016798,GO:0033554,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046352,GO:0050896,GO:0051716,GO:0071704,GO:1901575 3.2.1.93 ko:K01226 ko00500,map00500 R00837,R06113 RC00049 ko00000,ko00001,ko01000 GH13 iECW_1372.ECW_m4600,iEKO11_1354.EKO11_4072,iEcE24377_1341.EcE24377A_4811,iEcSMS35_1347.EcSMS35_4720,iWFL_1372.ECW_m4600 Bacteria 1TP53@1239,3F41I@33958,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain protein GOKNOHPG_01769 1033837.WANG_0315 1.8e-303 1047.7 Lactobacillaceae Bacteria 1W1FZ@1239,2FIUN@1,34AK2@2,3F4QI@33958,4HYXZ@91061 NA|NA|NA GOKNOHPG_01770 1423748.BALB01000020_gene1630 1.5e-79 302.0 Lactobacillaceae Bacteria 1W4GP@1239,28WWC@1,2ZIVN@2,3F5SC@33958,4I0DB@91061 NA|NA|NA GOKNOHPG_01771 326425.lhe_1046 4.1e-109 400.6 Lactobacillaceae msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 ko00000,ko01000 Bacteria 1TQ3E@1239,3F3YI@33958,4HAIV@91061,COG0225@1,COG0225@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine GOKNOHPG_01772 326425.lhe_1047 6e-62 243.4 Lactobacillaceae Bacteria 1W0V5@1239,2DYG7@1,349JS@2,3FC0P@33958,4HYMX@91061 NA|NA|NA S ASCH domain GOKNOHPG_01773 1423748.BALB01000020_gene1627 9.9e-17 91.7 Bacteria 4.4.1.5 ko:K01759 ko00620,map00620 R02530 RC00004,RC00740 ko00000,ko00001,ko01000 Bacteria COG0346@1,COG0346@2 NA|NA|NA E lactoylglutathione lyase activity GOKNOHPG_01774 1423748.BALB01000023_gene1714 4.8e-40 170.6 Lactobacillaceae Bacteria 1U56S@1239,29NKY@1,309IX@2,3F4YK@33958,4IEY2@91061 NA|NA|NA GOKNOHPG_01775 349123.Lreu23DRAFT_3295 6.5e-24 116.3 Lactobacillaceae Bacteria 1TSH6@1239,3F5HS@33958,4HEX8@91061,COG3385@1,COG3385@2 NA|NA|NA L PFAM transposase, IS4 family protein GOKNOHPG_01776 748671.LCRIS_00617 3.4e-39 167.9 Lactobacillaceae Bacteria 1TSH6@1239,3F5HS@33958,4HEX8@91061,COG3385@1,COG3385@2 NA|NA|NA L PFAM transposase, IS4 family protein GOKNOHPG_01777 891391.LAC30SC_00110 6.9e-106 390.2 Lactobacillaceae aacC 2.3.1.81 ko:K00662 ko00000,ko01000,ko01504 Bacteria 1V2QD@1239,3F635@33958,4HC3S@91061,COG2746@1,COG2746@2 NA|NA|NA V Aminoglycoside 3-N-acetyltransferase GOKNOHPG_01778 1033837.WANG_0359 4.2e-141 507.3 Lactobacillaceae 2.4.2.3 ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01876,R02484,R08229 RC00063 ko00000,ko00001,ko01000 Bacteria 1TQ71@1239,3F3UX@33958,4IRA8@91061,COG2820@1,COG2820@2 NA|NA|NA F Phosphorylase superfamily GOKNOHPG_01779 1033837.WANG_0358 7.6e-143 513.1 Lactobacillaceae 2.4.2.3 ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01876,R02484,R08229 RC00063 ko00000,ko00001,ko01000 Bacteria 1TQ71@1239,3F3UX@33958,4IRA8@91061,COG2820@1,COG2820@2 NA|NA|NA F Phosphorylase superfamily GOKNOHPG_01780 1033837.WANG_0357 2.2e-148 531.6 Lactobacillaceae 2.7.1.89 ko:K07251 ko00730,ko01100,map00730,map01100 R02134 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1VGF6@1239,3F5XT@33958,4HPU6@91061,COG0510@1,COG0510@2 NA|NA|NA M Phosphotransferase enzyme family GOKNOHPG_01781 1033837.WANG_0356 7.4e-86 323.2 Lactobacillaceae Bacteria 1UIME@1239,3F6E7@33958,4ISNB@91061,COG0645@1,COG0645@2 NA|NA|NA S AAA domain GOKNOHPG_01782 1033837.WANG_0355 1.6e-31 141.4 Bacteria cdd GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009972,GO:0009987,GO:0016020,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019856,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042455,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046108,GO:0046109,GO:0046112,GO:0046131,GO:0046132,GO:0046133,GO:0046134,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0072529,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 2.4.2.4,3.5.4.5 ko:K00758,ko:K01489 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 R01570,R01878,R02484,R02485,R08221,R08222,R08230 RC00063,RC00074,RC00514 ko00000,ko00001,ko01000 Bacteria COG0295@1,COG0295@2 NA|NA|NA F cytidine deaminase activity GOKNOHPG_01783 1423758.BN55_08820 1.1e-21 108.6 Lactobacillaceae cdd GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009972,GO:0009987,GO:0016020,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019856,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042455,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046108,GO:0046109,GO:0046112,GO:0046131,GO:0046132,GO:0046133,GO:0046134,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0072529,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 2.4.2.4,3.5.4.5 ko:K00758,ko:K01489 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 R01570,R01878,R02484,R02485,R08221,R08222,R08230 RC00063,RC00074,RC00514 ko00000,ko00001,ko01000 Bacteria 1V7IK@1239,3FC88@33958,4HMND@91061,COG0295@1,COG0295@2 NA|NA|NA F Cytidine and deoxycytidylate deaminase zinc-binding region GOKNOHPG_01784 1423758.BN55_08815 4.8e-134 484.2 Bacteria yxaM Bacteria COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GOKNOHPG_01785 1033837.WANG_0352 8e-51 206.1 Lactobacillaceae 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1U7WX@1239,3F4BS@33958,4HHQT@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain GOKNOHPG_01786 1033837.WANG_0351 1.9e-30 137.9 Lactobacillaceae Bacteria 1U6JV@1239,2DKR4@1,30AEY@2,3F820@33958,4IGCE@91061 NA|NA|NA S Protein of unknown function (DUF3923) GOKNOHPG_01787 1033837.WANG_0350 2.8e-42 177.6 Lactobacillaceae ko:K07473 ko00000,ko02048 Bacteria 1U67K@1239,29P71@1,30A54@2,3F79C@33958,4IFY5@91061 NA|NA|NA GOKNOHPG_01788 748671.LCRIS_01029 4e-57 227.3 Lactobacillaceae Bacteria 1UPY9@1239,2DMQA@1,32SZE@2,3F6TX@33958,4IVD8@91061 NA|NA|NA GOKNOHPG_01789 324831.LGAS_1054 2.5e-44 184.5 Lactobacillaceae Bacteria 1VJNA@1239,3F7BG@33958,4I1AJ@91061,COG1694@1,COG1694@2 NA|NA|NA S MazG-like family GOKNOHPG_01790 1033837.WANG_0348 8.6e-137 493.0 Lactobacillaceae Bacteria 1VCVA@1239,2E1K9@1,32WXS@2,3FBP4@33958,4HN4A@91061 NA|NA|NA S Protein of unknown function (DUF2785) GOKNOHPG_01791 1033837.WANG_0347 3e-78 297.7 Lactobacillaceae Bacteria 1V125@1239,3F5TK@33958,4HFVJ@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain GOKNOHPG_01792 1033837.WANG_0346 1e-23 115.5 Lactobacillaceae Bacteria 1U8GF@1239,2BU1J@1,32PA8@2,3FAYE@33958,4IIE8@91061 NA|NA|NA GOKNOHPG_01793 1033837.WANG_0345 6.4e-75 286.6 Lactobacillaceae msrB 1.8.4.11,1.8.4.12 ko:K07305,ko:K12267 ko00000,ko01000 Bacteria 1UPN0@1239,3F6H4@33958,4HGWN@91061,COG0229@1,COG0229@2 NA|NA|NA O peptide methionine sulfoxide reductase GOKNOHPG_01794 326425.lhe_1357 1.1e-46 192.2 Lactobacillaceae Bacteria 1U63R@1239,2DKNK@1,30A2I@2,3F6YT@33958,4IFT6@91061 NA|NA|NA GOKNOHPG_01795 326425.lhe_1358 1.5e-47 195.3 Lactobacillaceae glcU ko:K05340 ko00000,ko02000 2.A.7.5 Bacteria 1TQBN@1239,3F4K2@33958,4HAVH@91061,COG4975@1,COG4975@2 NA|NA|NA U sugar transport GOKNOHPG_01796 326425.lhe_1358 4.6e-77 294.3 Lactobacillaceae glcU ko:K05340 ko00000,ko02000 2.A.7.5 Bacteria 1TQBN@1239,3F4K2@33958,4HAVH@91061,COG4975@1,COG4975@2 NA|NA|NA U sugar transport GOKNOHPG_01798 272621.LBA1377 1.8e-38 167.2 Firmicutes Bacteria 1V8N3@1239,29WY6@1,30IKC@2 NA|NA|NA GOKNOHPG_01803 405566.lhv_1443 0.0 2088.2 Lactobacillaceae carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPID@1239,3F3MD@33958,4HAEY@91061,COG0458@1,COG0458@2 NA|NA|NA F Carbamoyl-phosphate synthase GOKNOHPG_01804 353496.LBU_1726 1.6e-207 728.4 Lactobacillaceae carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383,iYO844.BSU15510 Bacteria 1TQ8N@1239,3F43R@33958,4H9Z0@91061,COG0505@1,COG0505@2 NA|NA|NA F Carbamoyl-phosphate synthetase glutamine chain GOKNOHPG_01805 405566.lhv_1445 1e-237 828.9 Lactobacillaceae pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPQM@1239,3F3S3@33958,4HA90@91061,COG0044@1,COG0044@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily GOKNOHPG_01806 390333.Ldb2112 2e-180 638.3 Lactobacillaceae pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00608,ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15490 Bacteria 1TQ96@1239,3F4BQ@33958,4H9M6@91061,COG0540@1,COG0540@2 NA|NA|NA F Belongs to the ATCase OTCase family GOKNOHPG_01807 1033837.WANG_0335 3.9e-93 347.4 Lactobacillaceae pyrR GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000,ko03000 iHN637.CLJU_RS05275 Bacteria 1V3GV@1239,3F4SR@33958,4HGYE@91061,COG2065@1,COG2065@2 NA|NA|NA F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant GOKNOHPG_01808 1033837.WANG_0334 1.8e-167 595.1 Lactobacillaceae pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15540 Bacteria 1TPFV@1239,3F4PJ@33958,4HA5H@91061,COG0167@1,COG0167@2 NA|NA|NA F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily GOKNOHPG_01809 1033837.WANG_0333 2.2e-120 438.3 Lactobacillaceae pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750 Bacteria 1TPPH@1239,3F47Y@33958,4HAJ2@91061,COG0284@1,COG0284@2 NA|NA|NA F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) GOKNOHPG_01810 1033837.WANG_0332 1.1e-110 406.0 Lactobacillaceae pyrE 2.4.2.10,4.1.1.23 ko:K00762,ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15560 Bacteria 1V1BZ@1239,3F487@33958,4HFV7@91061,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) GOKNOHPG_01811 891391.LAC30SC_02360 2.9e-241 840.9 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3FCFA@33958,4HC8M@91061,COG2801@1,COG2801@2 NA|NA|NA L COG2963 Transposase and inactivated derivatives GOKNOHPG_01812 405566.lhv_1092 3.5e-160 570.9 Lactobacillaceae Bacteria 1UZVA@1239,3F4KP@33958,4HH09@91061,COG3039@1,COG3039@2 NA|NA|NA L An automated process has identified a potential problem with this gene model GOKNOHPG_01813 1423748.BALB01000022_gene1698 4.2e-179 634.0 Lactobacillaceae tcsA ko:K02058,ko:K07335 M00221 ko00000,ko00002,ko02000 3.A.1.2 Bacteria 1TPEU@1239,3F3MZ@33958,4HANH@91061,COG1744@1,COG1744@2 NA|NA|NA S ABC transporter substrate-binding protein PnrA-like GOKNOHPG_01814 405566.lhv_1516 1e-247 862.4 Lactobacillaceae xylG 3.6.3.17 ko:K02056,ko:K06400 M00221 ko00000,ko00002,ko01000,ko02000 3.A.1.2 Bacteria 1UYQA@1239,3F50N@33958,4HVSH@91061,COG3845@1,COG3845@2 NA|NA|NA S ABC transporter GOKNOHPG_01815 1423748.BALB01000022_gene1701 3.5e-168 597.8 Lactobacillaceae yufP GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 ko:K02057 M00221 ko00000,ko00002,ko02000 3.A.1.2 Bacteria 1TP1F@1239,3F59X@33958,4H9VE@91061,COG4603@1,COG4603@2 NA|NA|NA S Belongs to the binding-protein-dependent transport system permease family GOKNOHPG_01816 1423748.BALB01000022_gene1702 1.3e-160 572.4 Lactobacillaceae yufQ ko:K02057 M00221 ko00000,ko00002,ko02000 3.A.1.2 Bacteria 1TP8Y@1239,3F4AJ@33958,4HAX4@91061,COG1079@1,COG1079@2 NA|NA|NA S Belongs to the binding-protein-dependent transport system permease family GOKNOHPG_01817 326425.lhe_1371 0.0 1596.3 Lactobacillaceae 3.6.3.8 ko:K01537 ko00000,ko01000 3.A.3.2 Bacteria 1TPF5@1239,3F3KP@33958,4H9S5@91061,COG0474@1,COG0474@2 NA|NA|NA P P-type ATPase GOKNOHPG_01818 405566.lhv_1456 2.4e-199 701.4 Lactobacillaceae Bacteria 1TPJB@1239,3F4VX@33958,4HEY7@91061,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily GOKNOHPG_01819 405566.lhv_1457 7.2e-49 199.5 Lactobacillaceae Bacteria 1U62Q@1239,29P3D@1,30A1J@2,3F6W2@33958,4IFRV@91061 NA|NA|NA GOKNOHPG_01820 326425.lhe_1391 1.9e-46 191.4 Lactobacillaceae Bacteria 1VNIV@1239,2CE9Z@1,33CNB@2,3F7UX@33958,4HRR9@91061 NA|NA|NA GOKNOHPG_01821 405566.lhv_1460 3.4e-100 370.9 Lactobacillaceae sdaAB 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 1V8XQ@1239,3FC4T@33958,4HJWN@91061,COG1760@1,COG1760@2 NA|NA|NA E Serine dehydratase beta chain GOKNOHPG_01822 326425.lhe_1393 1.7e-87 328.9 Lactobacillaceae sdaAA 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 1TP79@1239,3F3X8@33958,4HAI1@91061,COG1760@1,COG1760@2 NA|NA|NA E L-serine dehydratase, iron-sulfur-dependent, alpha subunit GOKNOHPG_01823 1423748.BALB01000055_gene2082 2.4e-22 110.9 Lactobacillaceae sdaAA 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 1TP79@1239,3F3X8@33958,4HAI1@91061,COG1760@1,COG1760@2 NA|NA|NA E L-serine dehydratase, iron-sulfur-dependent, alpha subunit GOKNOHPG_01824 405566.lhv_1462 1.3e-51 208.8 Lactobacillaceae ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1V9YV@1239,3F7D5@33958,4HKC6@91061,COG2151@1,COG2151@2 NA|NA|NA S Iron-sulfur cluster assembly protein GOKNOHPG_01825 525365.HMPREF0548_0419 2e-14 89.0 Lactobacillaceae Bacteria 1W39C@1239,3F754@33958,4I0DV@91061,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation GOKNOHPG_01827 1423790.BN53_04365 6e-17 94.4 Lactobacillaceae Bacteria 1U85B@1239,29QIF@1,30BHX@2,3FAJI@33958,4II2U@91061 NA|NA|NA GOKNOHPG_01828 326425.lhe_1055 1.3e-12 79.3 Lactobacillaceae Bacteria 1VI5W@1239,2E37J@1,32Y79@2,3F8SQ@33958,4HP73@91061 NA|NA|NA GOKNOHPG_01830 1423748.BALB01000003_gene495 8.7e-50 203.4 Lactobacillaceae Bacteria 1VB5V@1239,3F3P4@33958,4HN9W@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family GOKNOHPG_01831 1423748.BALB01000003_gene495 2.5e-52 211.1 Lactobacillaceae Bacteria 1VB5V@1239,3F3P4@33958,4HN9W@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family GOKNOHPG_01832 1423748.BALB01000022_gene1676 3.1e-125 454.9 Lactobacillaceae Bacteria 1V7GB@1239,3F5VT@33958,4I28M@91061,COG4990@1,COG4990@2 NA|NA|NA G Peptidase_C39 like family GOKNOHPG_01833 1423748.BALB01000003_gene493 3e-26 124.0 Lactobacillaceae Bacteria 1U6VF@1239,2CKSK@1,31Y2F@2,3F8JR@33958,4IGPC@91061 NA|NA|NA GOKNOHPG_01836 1423790.BN53_09885 5.3e-08 63.9 Lactobacillaceae Bacteria 1TPT5@1239,3F4XH@33958,4HAPJ@91061,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold GOKNOHPG_01838 891391.LAC30SC_07850 6.7e-60 236.5 Lactobacillaceae oppA ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1TQ0N@1239,3F3KW@33958,4HARF@91061,COG0747@1,COG0747@2 NA|NA|NA E ABC transporter substrate-binding protein GOKNOHPG_01839 525365.HMPREF0548_0230 8.8e-148 529.6 Lactobacillaceae cjaA ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TT11@1239,3F54P@33958,4HFBQ@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter substrate-binding protein GOKNOHPG_01840 525365.HMPREF0548_0231 4.8e-118 430.6 Lactobacillaceae glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,3FC3P@33958,4HDK7@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein GOKNOHPG_01841 326425.lhe_1380 2.6e-86 325.1 Lactobacillaceae ko:K02029,ko:K10040 ko02010,map02010 M00228,M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3 Bacteria 1TR7R@1239,3F45E@33958,4HGVA@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease GOKNOHPG_01842 1423748.BALB01000022_gene1687 3.2e-105 387.9 Lactobacillaceae papP ko:K02029 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TRU3@1239,3F3XD@33958,4HGE1@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter, permease protein GOKNOHPG_01843 525365.HMPREF0548_1733 4.5e-96 358.2 Lactobacillaceae Bacteria 1V0EH@1239,3F4KW@33958,4HXBI@91061,COG1672@1,COG1672@2 NA|NA|NA S PFAM Archaeal ATPase GOKNOHPG_01844 405566.lhv_1473 5.7e-222 776.5 Lactobacillaceae Bacteria 1UG8H@1239,29V6Q@1,30GKE@2,3F5M6@33958,4IF4J@91061 NA|NA|NA S SLAP domain GOKNOHPG_01845 405566.lhv_1475 5.6e-236 823.2 Lactobacillaceae Bacteria 1UK2K@1239,29XAY@1,30J0K@2,3F5Q0@33958,4ITGE@91061 NA|NA|NA S Domain of unknown function (DUF3883) GOKNOHPG_01846 1033837.WANG_1566 3.8e-63 247.3 Lactobacillaceae Bacteria 1UN2R@1239,29Y7R@1,30K1D@2,3F8ZW@33958,4IU5N@91061 NA|NA|NA GOKNOHPG_01847 326425.lhe_0140 9.8e-177 625.9 Lactobacillaceae Bacteria 1UY1T@1239,3F5D8@33958,4I2Y3@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF915) GOKNOHPG_01848 405566.lhv_0130 1.1e-283 981.9 Lactobacillaceae cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPKY@1239,3F3SF@33958,4H9TI@91061,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol GOKNOHPG_01849 405566.lhv_0129 6.6e-84 316.6 Lactobacillaceae Bacteria 1U58T@1239,2CCJZ@1,303JM@2,3F565@33958,4IF00@91061 NA|NA|NA GOKNOHPG_01850 405566.lhv_0128 9.1e-89 332.8 Lactobacillaceae cobB ko:K12410 ko00000,ko01000 Bacteria 1TQKD@1239,3F4WS@33958,4HC4I@91061,COG0846@1,COG0846@2 NA|NA|NA K SIR2 family GOKNOHPG_01851 326425.lhe_0136 1.9e-89 335.1 Lactobacillaceae ogt 2.1.1.63 ko:K00567,ko:K10778,ko:K13531 ko00000,ko01000,ko03000,ko03400 Bacteria 1VA03@1239,3F4TG@33958,4HETA@91061,COG0350@1,COG0350@2 NA|NA|NA L 6-O-methylguanine DNA methyltransferase, DNA binding domain GOKNOHPG_01852 1033837.WANG_1672 9e-123 446.4 Lactobacillaceae terC ko:K05794 ko00000 Bacteria 1TQ09@1239,3FB68@33958,4HB99@91061,COG0861@1,COG0861@2 NA|NA|NA P Integral membrane protein TerC family GOKNOHPG_01853 326425.lhe_0134 2.4e-62 244.6 Lactobacillaceae yeaO Bacteria 1VABH@1239,3F715@33958,4HKI2@91061,COG3189@1,COG3189@2 NA|NA|NA S Protein of unknown function, DUF488 GOKNOHPG_01854 326425.lhe_0133 4e-121 440.7 Lactobacillaceae mpg GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1E6@1239,3F59D@33958,4HG5E@91061,COG2094@1,COG2094@2 NA|NA|NA L Belongs to the DNA glycosylase MPG family GOKNOHPG_01855 326425.lhe_0132 8.7e-290 1002.3 Lactobacillaceae glnP ko:K02029,ko:K02030,ko:K17073,ko:K17074 ko02010,map02010 M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1TPM3@1239,3F48Y@33958,4HAS2@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2 NA|NA|NA P ABC transporter permease GOKNOHPG_01856 405566.lhv_0122 1.4e-136 492.3 Lactobacillaceae glnQ ko:K17074,ko:K17076 ko02010,map02010 M00589 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.20 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein GOKNOHPG_01857 326425.lhe_0130 2.2e-159 568.2 Lactobacillaceae Bacteria 1V4V2@1239,3F4P0@33958,4HI4X@91061,COG1403@1,COG1403@2 NA|NA|NA L HNH nucleases GOKNOHPG_01858 525365.HMPREF0548_1796 5e-119 433.7 Lactobacillaceae yfbR ko:K07023 ko00000 Bacteria 1TSDU@1239,3F4RZ@33958,4HA8H@91061,COG1896@1,COG1896@2 NA|NA|NA S HD containing hydrolase-like enzyme GOKNOHPG_01860 891391.LAC30SC_09010 2.1e-14 84.7 Lactobacillaceae Bacteria 1VD0Q@1239,3FBE6@33958,4IPQG@91061,COG3212@1,COG3212@2 NA|NA|NA S Peptidase propeptide and YPEB domain GOKNOHPG_01861 326425.lhe_0126 3.5e-62 244.2 Lactobacillaceae Bacteria 1VR8Q@1239,2F08C@1,33TBR@2,3F6XD@33958,4HTKM@91061 NA|NA|NA GOKNOHPG_01862 1033837.WANG_1665 5.9e-17 92.4 Lactobacillaceae Bacteria 1U6MZ@1239,29PIJ@1,30AGQ@2,3F868@33958,4IGEU@91061 NA|NA|NA GOKNOHPG_01863 1033837.WANG_1664 1.2e-59 235.7 Lactobacillaceae glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1UGF1@1239,3FC1C@33958,4HBM4@91061,COG0584@1,COG0584@2,COG4781@1,COG4781@2 NA|NA|NA C Membrane domain of glycerophosphoryl diester phosphodiesterase GOKNOHPG_01864 1033837.WANG_1664 1.9e-30 138.3 Lactobacillaceae glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1UGF1@1239,3FC1C@33958,4HBM4@91061,COG0584@1,COG0584@2,COG4781@1,COG4781@2 NA|NA|NA C Membrane domain of glycerophosphoryl diester phosphodiesterase GOKNOHPG_01865 1033837.WANG_1664 1.3e-12 78.2 Lactobacillaceae glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1UGF1@1239,3FC1C@33958,4HBM4@91061,COG0584@1,COG0584@2,COG4781@1,COG4781@2 NA|NA|NA C Membrane domain of glycerophosphoryl diester phosphodiesterase GOKNOHPG_01866 405566.lhv_1324 1.6e-62 245.4 Lactobacillaceae 3.4.21.96 ko:K01361 ko00000,ko01000,ko01002,ko03110 Bacteria 1U5RD@1239,29NWN@1,309UR@2,3F6D7@33958,4IFFJ@91061 NA|NA|NA S SLAP domain GOKNOHPG_01867 405566.lhv_1323 0.0 1420.6 Lactobacillaceae 3.6.3.2,3.6.3.6 ko:K01531,ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 3.A.3.3,3.A.3.4 Bacteria 1TPF5@1239,3F55J@33958,4HVA4@91061,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus GOKNOHPG_01868 405566.lhv_1322 1.8e-156 558.5 Lactobacillaceae lysR5 Bacteria 1UXFR@1239,3F4XG@33958,4HBNZ@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain GOKNOHPG_01869 1423748.BALB01000013_gene1301 3.7e-59 234.2 Lactobacillaceae arcA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0008218,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0016990,GO:0018101,GO:0018193,GO:0018195,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 R00552 RC00177 ko00000,ko00001,ko01000 Bacteria 1TQWS@1239,3F4VJ@33958,4HCMG@91061,COG2235@1,COG2235@2 NA|NA|NA E Arginine GOKNOHPG_01870 891391.LAC30SC_06905 7.6e-88 330.1 Lactobacillaceae arcA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0008218,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0016990,GO:0018101,GO:0018193,GO:0018195,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 R00552 RC00177 ko00000,ko00001,ko01000 Bacteria 1TQWS@1239,3F4VJ@33958,4HCMG@91061,COG2235@1,COG2235@2 NA|NA|NA E Arginine GOKNOHPG_01871 1423748.BALB01000013_gene1302 1e-51 209.1 Lactobacillaceae argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.7.2.2 ko:K00611,ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00220,map00230,map00910,map01100,map01110,map01120,map01130,map01200,map01230 M00029,M00844 R00150,R01395,R01398 RC00002,RC00043,RC00096,RC02803,RC02804 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPF2@1239,3F48K@33958,4H9X8@91061,COG0078@1,COG0078@2 NA|NA|NA E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline GOKNOHPG_01872 1423748.BALB01000013_gene1302 5.8e-62 243.4 Lactobacillaceae argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.7.2.2 ko:K00611,ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00220,map00230,map00910,map01100,map01110,map01120,map01130,map01200,map01230 M00029,M00844 R00150,R01395,R01398 RC00002,RC00043,RC00096,RC02803,RC02804 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPF2@1239,3F48K@33958,4H9X8@91061,COG0078@1,COG0078@2 NA|NA|NA E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline GOKNOHPG_01873 1423748.BALB01000013_gene1303 9.9e-68 262.7 Lactobacillaceae arcC 2.7.2.2 ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 R00150,R01395 RC00002,RC00043,RC02803,RC02804 ko00000,ko00001,ko01000 Bacteria 1TP9H@1239,3F3T4@33958,4H9QD@91061,COG0549@1,COG0549@2 NA|NA|NA E Belongs to the carbamate kinase family GOKNOHPG_01874 1423748.BALB01000013_gene1303 8e-52 209.5 Lactobacillaceae arcC 2.7.2.2 ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 R00150,R01395 RC00002,RC00043,RC02803,RC02804 ko00000,ko00001,ko01000 Bacteria 1TP9H@1239,3F3T4@33958,4H9QD@91061,COG0549@1,COG0549@2 NA|NA|NA E Belongs to the carbamate kinase family GOKNOHPG_01875 326425.lhe_1249 3.4e-97 360.9 Lactobacillaceae citX 2.4.2.52,2.7.7.61 ko:K05964,ko:K13927 ko02020,map02020 R09675,R10706 RC00049,RC00063 ko00000,ko00001,ko01000 Bacteria 1VB3E@1239,3F74S@33958,4HMZ5@91061,COG3697@1,COG3697@2 NA|NA|NA HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase GOKNOHPG_01876 405566.lhv_1311 4.2e-209 733.8 Lactobacillaceae Bacteria 1V7PR@1239,3FBA9@33958,4HV9V@91061,COG4552@1,COG4552@2 NA|NA|NA S Sterol carrier protein domain GOKNOHPG_01877 326425.lhe_1247 2.5e-19 100.5 Lactobacillaceae Bacteria 1U6K3@1239,2CETM@1,30AF4@2,3F82Q@33958,4IGCS@91061 NA|NA|NA GOKNOHPG_01878 405566.lhv_1310 3.5e-106 391.0 Lactobacillaceae Bacteria 1TT5B@1239,3F6BZ@33958,4HK1M@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain GOKNOHPG_01879 1423748.BALB01000013_gene1308 2.8e-32 144.1 Lactobacillaceae Bacteria 1U5E5@1239,2AJU9@1,31AGT@2,3F5PH@33958,4IF5F@91061 NA|NA|NA GOKNOHPG_01880 1423748.BALB01000007_gene835 5e-15 86.3 Lactobacillaceae VY92_08690 5.3.1.32 ko:K11530 ko02024,map02024 ko00000,ko00001,ko01000 Bacteria 1VVR5@1239,3F5NS@33958,4HWFJ@91061,COG1359@1,COG1359@2 NA|NA|NA G Antibiotic biosynthesis monooxygenase GOKNOHPG_01881 1423748.BALB01000007_gene835 2.6e-72 278.1 Lactobacillaceae VY92_08690 5.3.1.32 ko:K11530 ko02024,map02024 ko00000,ko00001,ko01000 Bacteria 1VVR5@1239,3F5NS@33958,4HWFJ@91061,COG1359@1,COG1359@2 NA|NA|NA G Antibiotic biosynthesis monooxygenase GOKNOHPG_01882 1423748.BALB01000007_gene836 4.3e-158 563.9 Lactobacillaceae lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iYO844.BSU03790 Bacteria 1TPQJ@1239,3F48V@33958,4HAEP@91061,COG0527@1,COG0527@2 NA|NA|NA E Belongs to the aspartokinase family GOKNOHPG_01910 326425.lhe_1609 1.4e-220 771.9 Lactobacillaceae mgs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 GT4 Bacteria 1TPTA@1239,3FC1E@33958,4IPQK@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase 4-like domain GOKNOHPG_01911 326425.lhe_1608 8.4e-201 706.1 Lactobacillaceae cpoA GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901576 ko:K13678 R10865 RC00005,RC00049 ko00000,ko01000,ko01003 GT4 Bacteria 1TPSS@1239,3F47X@33958,4HB9F@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase, group 1 family protein GOKNOHPG_01912 405566.lhv_0469 3.3e-178 630.9 Lactobacillaceae mprF ko:K07027 ko00000,ko02000 4.D.2 Bacteria 1TR9T@1239,3FBJD@33958,4IQVI@91061,COG0392@1,COG0392@2 NA|NA|NA S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms GOKNOHPG_01913 405566.lhv_0470 0.0 1343.9 Lactobacillaceae ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 R05081,R10849 RC00017 ko00000,ko00001,ko01000 Bacteria 1TRMA@1239,3F3R7@33958,4H9S0@91061,COG1368@1,COG1368@2 NA|NA|NA M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily GOKNOHPG_01914 326425.lhe_1605 2.3e-29 134.4 Lactobacillaceae secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VEQR@1239,3F7IQ@33958,4HNKC@91061,COG1314@1,COG1314@2 NA|NA|NA U Preprotein translocase GOKNOHPG_01915 405566.lhv_0472 0.0 1487.6 Lactobacillaceae rnr ko:K12573,ko:K12585 ko03018,map03018 M00391 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 1TQ1G@1239,3F4EC@33958,4HBBH@91061,COG0557@1,COG0557@2 NA|NA|NA J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs GOKNOHPG_01916 326425.lhe_1603 1.5e-77 295.4 Lactobacillaceae smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 ko:K03664 ko00000 Bacteria 1V3IJ@1239,3F65B@33958,4HGZX@91061,COG0691@1,COG0691@2 NA|NA|NA J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA GOKNOHPG_01917 334390.LAF_0673 6.9e-71 274.2 Lactobacillaceae Bacteria 1UHY6@1239,3FBS3@33958,4ISAK@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein GOKNOHPG_01918 1114972.AUAW01000013_gene1049 5.3e-27 127.1 Lactobacillaceae Bacteria 1TQ93@1239,3F4RD@33958,4HDNZ@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein GOKNOHPG_01919 543734.LCABL_03570 3.7e-131 474.2 Lactobacillaceae Bacteria 1TRSF@1239,3F3UG@33958,4HDM3@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase, catalytic core GOKNOHPG_01920 1423748.BALB01000012_gene1204 1e-41 175.6 Lactobacillaceae Bacteria 1VA6G@1239,3F72A@33958,4HKYT@91061,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor GOKNOHPG_01921 405566.lhv_1842 4.2e-156 557.4 Lactobacillaceae psaA ko:K02077 M00244 ko00000,ko00002,ko02000 3.A.1.15 Bacteria 1TRKU@1239,3F4B9@33958,4HAKT@91061,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family GOKNOHPG_01922 326425.lhe_0375 1.9e-115 421.8 Lactobacillaceae fhuC ko:K02074,ko:K09817 ko02010,map02010 M00242,M00244 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 1TQ68@1239,3F49M@33958,4HAZI@91061,COG1121@1,COG1121@2 NA|NA|NA P ABC transporter GOKNOHPG_01923 326425.lhe_0376 1.4e-128 465.7 Lactobacillaceae znuB ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 1V0SX@1239,3F4BC@33958,4HE09@91061,COG1108@1,COG1108@2 NA|NA|NA U ABC 3 transport family GOKNOHPG_01924 1033837.WANG_p1103 2.7e-244 850.9 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TRNY@1239,3F55P@33958,4HBKP@91061,COG0675@1,COG0675@2 NA|NA|NA L transposase, IS605 OrfB family GOKNOHPG_01925 1033837.WANG_p1104 1.7e-72 278.5 Bacteria ko:K07491 ko00000 Bacteria COG1943@1,COG1943@2 NA|NA|NA L Transposase GOKNOHPG_01926 326425.lhe_0377 3.2e-232 810.8 Lactobacillaceae ydjN GO:0000099,GO:0000101,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006791,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015184,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015811,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:0098656,GO:1901682,GO:1902475,GO:1903825,GO:1905039 ko:K06956 ko00000 Bacteria 1UPUK@1239,3FB7M@33958,4HAJY@91061,COG1823@1,COG1823@2 NA|NA|NA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family GOKNOHPG_01927 1423748.BALB01000012_gene1200 1.8e-42 178.7 Lactobacillaceae lctP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03303 ko00000,ko02000 2.A.14 Bacteria 1TQNM@1239,3F4EG@33958,4HAF3@91061,COG1620@1,COG1620@2 NA|NA|NA C L-lactate permease GOKNOHPG_01928 326425.lhe_0379 9.6e-40 169.1 Lactobacillaceae Bacteria 1U6IT@1239,29PFZ@1,30AE4@2,3F800@33958,4IGB6@91061 NA|NA|NA S Enterocin A Immunity GOKNOHPG_01929 405566.lhv_0475 7.4e-155 553.1 Lactobacillaceae msmR7 Bacteria 1V0Z0@1239,3F53H@33958,4ISD2@91061,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein GOKNOHPG_01930 748671.LCRIS_01512 2.4e-130 472.2 Lactobacillaceae scrB 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 GH32 Bacteria 1TPAE@1239,3F4UD@33958,4H9Y7@91061,COG1621@1,COG1621@2 NA|NA|NA G invertase GOKNOHPG_01931 748671.LCRIS_01510 9.1e-202 709.5 Lactobacillaceae scrA 2.7.1.208,2.7.1.211 ko:K02749,ko:K02750,ko:K02755,ko:K02756,ko:K02757,ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00268,M00269,M00271 R00811,R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.10,4.A.1.1.16,4.A.1.1.4,4.A.1.1.8,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system GOKNOHPG_01932 748671.LCRIS_01510 1.3e-79 302.8 Lactobacillaceae scrA 2.7.1.208,2.7.1.211 ko:K02749,ko:K02750,ko:K02755,ko:K02756,ko:K02757,ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00268,M00269,M00271 R00811,R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.10,4.A.1.1.16,4.A.1.1.4,4.A.1.1.8,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system GOKNOHPG_01933 1033837.WANG_0302 3.5e-10 70.5 Lactobacillaceae rafA GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009987,GO:0010033,GO:0015925,GO:0016043,GO:0016052,GO:0016787,GO:0016798,GO:0022607,GO:0042221,GO:0043933,GO:0044085,GO:0044238,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901545,GO:1901575,GO:1901700 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 Bacteria 1TQF4@1239,3F3RU@33958,4HA5R@91061,COG3345@1,COG3345@2 NA|NA|NA G alpha-galactosidase GOKNOHPG_01934 1423748.BALB01000003_gene462 2.1e-169 602.1 Lactobacillaceae rafA GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009987,GO:0010033,GO:0015925,GO:0016043,GO:0016052,GO:0016787,GO:0016798,GO:0022607,GO:0042221,GO:0043933,GO:0044085,GO:0044238,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901545,GO:1901575,GO:1901700 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 Bacteria 1TQF4@1239,3F3RU@33958,4HA5R@91061,COG3345@1,COG3345@2 NA|NA|NA G alpha-galactosidase GOKNOHPG_01935 748671.LCRIS_01509 3.1e-47 194.5 Lactobacillaceae rafA 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 Bacteria 1TQF4@1239,3F3RU@33958,4HA5R@91061,COG3345@1,COG3345@2 NA|NA|NA G alpha-galactosidase GOKNOHPG_01936 405566.lhv_0480 6.7e-187 659.8 Lactobacillaceae manL 2.7.1.191 ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1TQJ4@1239,3FC7R@33958,4HTTA@91061,COG2893@1,COG2893@2,COG3444@1,COG3444@2 NA|NA|NA G PTS system sorbose subfamily IIB component GOKNOHPG_01937 326425.lhe_0492 6.9e-134 483.4 Lactobacillaceae manY ko:K02795,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1TPKK@1239,3F3V5@33958,4H9QI@91061,COG3715@1,COG3715@2 NA|NA|NA G PTS system GOKNOHPG_01938 405566.lhv_0482 1.2e-171 609.0 Lactobacillaceae manN ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1TQA3@1239,3F3KR@33958,4HA3K@91061,COG3716@1,COG3716@2 NA|NA|NA G system, mannose fructose sorbose family IID component GOKNOHPG_01939 326425.lhe_0494 7.6e-64 249.6 Lactobacillaceae manO Bacteria 1V6KV@1239,3FB56@33958,4HX8Z@91061,COG4687@1,COG4687@2 NA|NA|NA S Domain of unknown function (DUF956) GOKNOHPG_01940 326425.lhe_0495 7.5e-61 239.6 Lactobacillaceae Bacteria 1TP77@1239,3F3VP@33958,4HAZB@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator GOKNOHPG_01941 326425.lhe_0495 1.9e-19 101.3 Lactobacillaceae Bacteria 1TP77@1239,3F3VP@33958,4HAZB@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator GOKNOHPG_01942 405566.lhv_1785 0.0 1407.1 Lactobacillaceae yaaO 4.1.1.17,4.1.1.19 ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00133,M00134 R00566,R00670 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 1TNZ9@1239,3F3TV@33958,4HBGC@91061,COG1982@1,COG1982@2 NA|NA|NA E Orn/Lys/Arg decarboxylase, C-terminal domain GOKNOHPG_01943 326425.lhe_0436 1.2e-266 925.2 Lactobacillaceae ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1UYSD@1239,3F48U@33958,4IPMN@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease GOKNOHPG_01944 748671.LCRIS_01240 6.7e-59 234.6 Lactobacillaceae Bacteria 1U7Z5@1239,29QEJ@1,30BDX@2,3FACF@33958,4IHWH@91061 NA|NA|NA GOKNOHPG_01945 1423816.BACQ01000055_gene2101 3.5e-94 350.9 Lactobacillaceae ko:K07493 ko00000 Bacteria 1TP4C@1239,3F4RA@33958,4HAXJ@91061,COG3328@1,COG3328@2 NA|NA|NA L Transposase GOKNOHPG_01946 1423748.BALB01000003_gene479 1.3e-90 339.0 Lactobacillaceae Bacteria 1U53J@1239,29NJI@1,309HE@2,3F4CT@33958,4IEUW@91061 NA|NA|NA GOKNOHPG_01948 1423748.BALB01000003_gene477 3.8e-58 231.1 Lactobacillaceae yxjG 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPDQ@1239,3F49P@33958,4HADW@91061,COG0620@1,COG0620@2 NA|NA|NA E methionine synthase, vitamin-B12 independent GOKNOHPG_01949 1423748.BALB01000003_gene476 1.8e-89 335.1 Lactobacillaceae luxS GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300 Bacteria 1V1CH@1239,3F4W2@33958,4HFPR@91061,COG1854@1,COG1854@2 NA|NA|NA H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) GOKNOHPG_01950 1423748.BALB01000003_gene475 1e-196 692.6 Lactobacillaceae yjeM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1TRFS@1239,3F4J0@33958,4HA0N@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid GOKNOHPG_01951 326425.lhe_0515 3.4e-227 793.9 Lactobacillaceae nagA 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 R02059 RC00166,RC00300 ko00000,ko00001,ko01000 Bacteria 1TPFK@1239,3F40F@33958,4HC6C@91061,COG1820@1,COG1820@2 NA|NA|NA G Belongs to the metallo-dependent hydrolases superfamily. NagA family GOKNOHPG_01952 324831.LGAS_1686 1.8e-97 362.5 Lactobacillaceae rpiR1 Bacteria 1TR5E@1239,3F49F@33958,4HGM0@91061,COG1737@1,COG1737@2 NA|NA|NA K Helix-turn-helix domain, rpiR family GOKNOHPG_01953 324831.LGAS_1687 2.3e-86 325.1 Lactobacillaceae nanE 5.1.3.9 ko:K01788 ko00520,map00520 R02087 RC00290 ko00000,ko00001,ko01000 Bacteria 1TSR7@1239,3F529@33958,4HBPF@91061,COG3010@1,COG3010@2 NA|NA|NA G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) GOKNOHPG_01954 324831.LGAS_1688 8.4e-138 496.5 Lactobacillaceae ptsG 2.7.1.199,2.7.1.208 ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.3 Bacteria 1TPJ8@1239,3F44V@33958,4HA8X@91061,COG1263@1,COG1263@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system, EIIB GOKNOHPG_01955 1545701.LACWKB10_0102 5.9e-19 99.8 Lactobacillaceae ptsG 2.7.1.199,2.7.1.208 ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.3 Bacteria 1TPJ8@1239,3F44V@33958,4HA8X@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system, EIIB GOKNOHPG_01956 324831.LGAS_1688 3.8e-92 344.7 Lactobacillaceae ptsG 2.7.1.199,2.7.1.208 ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.3 Bacteria 1TPJ8@1239,3F44V@33958,4HA8X@91061,COG1263@1,COG1263@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system, EIIB GOKNOHPG_01957 1033837.WANG_1178 1.3e-216 758.8 Lactobacillaceae naiP Bacteria 1TQM0@1239,3F3SE@33958,4HATA@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GOKNOHPG_01958 1033837.WANG_1177 0.0 1235.3 Lactobacillaceae XK27_00340 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPV2@1239,3F4S2@33958,4HB9S@91061,COG0737@1,COG0737@2 NA|NA|NA F Belongs to the 5'-nucleotidase family GOKNOHPG_01959 1033837.WANG_1176 8.8e-09 65.1 Lactobacillaceae oppA ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F5SJ@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter GOKNOHPG_01960 1033837.WANG_1176 1.8e-41 174.9 Lactobacillaceae oppA ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F5SJ@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter GOKNOHPG_01961 326425.lhe_0669 2.5e-231 807.7 Lactobacillaceae pacL 3.6.3.8,3.6.3.9 ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 ko00000,ko00001,ko01000,ko04147 3.A.3.1,3.A.3.2 Bacteria 1TPF5@1239,3FC0Z@33958,4HTQ4@91061,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus GOKNOHPG_01962 1423748.BALB01000004_gene625 1.1e-44 185.7 Lactobacillaceae pacL 3.6.3.8,3.6.3.9 ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 ko00000,ko00001,ko01000,ko04147 3.A.3.1,3.A.3.2 Bacteria 1TPF5@1239,3FC0Z@33958,4HTQ4@91061,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus GOKNOHPG_01963 326425.lhe_0669 2.9e-58 231.1 Lactobacillaceae pacL 3.6.3.8,3.6.3.9 ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 ko00000,ko00001,ko01000,ko04147 3.A.3.1,3.A.3.2 Bacteria 1TPF5@1239,3FC0Z@33958,4HTQ4@91061,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus GOKNOHPG_01964 405566.lhv_0701 1.6e-40 171.8 Lactobacillaceae pacL 3.6.3.8,3.6.3.9 ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 ko00000,ko00001,ko01000,ko04147 3.A.3.1,3.A.3.2 Bacteria 1TPF5@1239,3FC0Z@33958,4HTQ4@91061,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus GOKNOHPG_01965 405566.lhv_0700 1.7e-201 708.4 Lactobacillaceae pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ3J@1239,3F3RC@33958,4HBHB@91061,COG2706@1,COG2706@2 NA|NA|NA G Lactonase, 7-bladed beta-propeller GOKNOHPG_01966 405566.lhv_0699 1.4e-55 222.2 Lactobacillaceae Bacteria 1V6V7@1239,3F417@33958,4HITM@91061,COG0398@1,COG0398@2 NA|NA|NA S SNARE associated Golgi protein GOKNOHPG_01967 326425.lhe_0667 3.1e-41 174.1 Lactobacillaceae Bacteria 1V6V7@1239,3F417@33958,4HITM@91061,COG0398@1,COG0398@2 NA|NA|NA S SNARE associated Golgi protein GOKNOHPG_01968 326425.lhe_0666 0.0 1214.1 Lactobacillaceae mycA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046983,GO:0048037,GO:0050151,GO:0050660,GO:0050662,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901363 4.2.1.53 ko:K10254 ko00000,ko01000 Bacteria 1TQZ6@1239,3F3QX@33958,4HAYH@91061,COG4716@1,COG4716@2 NA|NA|NA S Myosin-crossreactive antigen GOKNOHPG_01969 326425.lhe_0665 2.6e-166 591.3 Lactobacillaceae rluD 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 Bacteria 1TS1T@1239,3F46Z@33958,4HBRY@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil GOKNOHPG_01970 405566.lhv_0694 3.9e-153 547.4 Lactobacillaceae nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895 Bacteria 1TRB3@1239,3F45D@33958,4HB08@91061,COG0061@1,COG0061@2 NA|NA|NA F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP GOKNOHPG_01971 326425.lhe_0663 2.1e-114 418.3 Lactobacillaceae yjbM 2.7.6.5 ko:K07816 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 1TQ2F@1239,3F452@33958,4HA3Q@91061,COG2357@1,COG2357@2 NA|NA|NA S RelA SpoT domain protein GOKNOHPG_01972 326425.lhe_0662 9.5e-112 409.5 Lactobacillaceae yjbK Bacteria 1TTVM@1239,3F4YS@33958,4I4A3@91061,COG4116@1,COG4116@2 NA|NA|NA S CYTH GOKNOHPG_01973 405566.lhv_0691 2.1e-111 408.3 Lactobacillaceae yjbH GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 Bacteria 1TQ8K@1239,3F6QR@33958,4HAI8@91061,COG2761@1,COG2761@2 NA|NA|NA Q Thioredoxin GOKNOHPG_01974 257314.LJ_1144 6.1e-245 853.2 Lactobacillaceae mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 1TPT1@1239,3F49Y@33958,4HAEA@91061,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system GOKNOHPG_01975 257314.LJ_1143 8.5e-43 179.5 Lactobacillaceae yitW ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1V9YV@1239,3F7D5@33958,4HKC6@91061,COG2151@1,COG2151@2 NA|NA|NA S Iron-sulfur cluster assembly protein GOKNOHPG_01976 257314.LJ_1142 1.3e-268 931.8 Lactobacillaceae sufB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 ko:K07033,ko:K09014 ko00000 Bacteria 1TQ21@1239,3F44I@33958,4HA1Z@91061,COG0719@1,COG0719@2 NA|NA|NA O assembly protein SufB GOKNOHPG_01977 257314.LJ_1141 1.4e-62 245.7 Lactobacillaceae nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 ko:K04488 ko00000 Bacteria 1V3H9@1239,3F6WP@33958,4HIJ0@91061,COG0822@1,COG0822@2 NA|NA|NA C SUF system FeS assembly protein, NifU family GOKNOHPG_01978 257314.LJ_1140 8.2e-187 659.8 Lactobacillaceae sufS 2.8.1.7,4.4.1.16 ko:K04487,ko:K11717 ko00450,ko00730,ko01100,ko04122,map00450,map00730,map01100,map04122 R03599,R07460,R11528,R11529 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TQ1W@1239,3F3UP@33958,4HA6Z@91061,COG0520@1,COG0520@2 NA|NA|NA E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine GOKNOHPG_01979 257314.LJ_1139 6.1e-195 686.8 Lactobacillaceae sufD ko:K07033,ko:K09015 ko00000 Bacteria 1TRT0@1239,3F4BR@33958,4HB6W@91061,COG0719@1,COG0719@2 NA|NA|NA O FeS assembly protein SufD GOKNOHPG_01980 257314.LJ_1138 1.1e-141 509.2 Lactobacillaceae sufC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 ko:K09013 ko00000,ko02000 iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710 Bacteria 1TQ98@1239,3F3XT@33958,4HAD9@91061,COG0396@1,COG0396@2 NA|NA|NA O FeS assembly ATPase SufC GOKNOHPG_01981 324831.LGAS_0948 1.2e-115 422.5 Lactobacillaceae brnQ GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 ko:K03311 ko00000 2.A.26 Bacteria 1TQIS@1239,3F3KC@33958,4HAKA@91061,COG1114@1,COG1114@2 NA|NA|NA U Component of the transport system for branched-chain amino acids GOKNOHPG_01983 1423767.BALU01000007_gene628 2.2e-127 462.2 Lactobacillaceae Bacteria 1UJ2D@1239,3F5DF@33958,4ISZI@91061,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation GOKNOHPG_01987 1033837.WANG_0557 5.4e-75 287.0 Lactobacillaceae dps ko:K04047 ko00000,ko03036 Bacteria 1VCVJ@1239,3F5WI@33958,4HMBD@91061,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family GOKNOHPG_01988 891391.LAC30SC_08610 1.4e-39 168.3 Lactobacillaceae Bacteria 1U749@1239,3F8YF@33958,4IGYW@91061,COG2826@1,COG2826@2 NA|NA|NA L transposase and inactivated derivatives, IS30 family GOKNOHPG_01989 1033837.WANG_1663 1.2e-55 222.2 Lactobacillaceae Bacteria 1VY7K@1239,2F916@1,341CT@2,3F70S@33958,4HX4B@91061 NA|NA|NA S Iron-sulphur cluster biosynthesis GOKNOHPG_01990 1045004.OKIT_0523 0.0 1263.4 Leuconostocaceae traA Bacteria 1VQWC@1239,4AYTM@81850,4HD6B@91061,COG0507@1,COG0507@2 NA|NA|NA L MobA/MobL family GOKNOHPG_01991 908339.HMPREF9265_1193 3.6e-26 123.6 Lactobacillaceae Bacteria 1U69C@1239,29P8B@1,30A6E@2,3F7CM@33958,4IG0H@91061 NA|NA|NA GOKNOHPG_01992 1033837.WANG_1719 3.1e-41 174.1 Lactobacillaceae Bacteria 1VKZC@1239,2EJES@1,33D5R@2,3F6Y2@33958,4HRGI@91061 NA|NA|NA GOKNOHPG_01993 1033837.WANG_0286 2e-71 275.0 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3FCFA@33958,4HC8M@91061,COG2801@1,COG2801@2 NA|NA|NA L COG2963 Transposase and inactivated derivatives GOKNOHPG_01997 908339.HMPREF9265_1394 6.8e-41 174.9 Lactobacillaceae repA Bacteria 1VHQA@1239,2DP1C@1,3304N@2,3F55E@33958,4HPY6@91061 NA|NA|NA S Replication initiator protein A GOKNOHPG_01998 326425.lhe_1022 3.4e-117 427.6 Lactobacillaceae XK27_07525 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1U7WX@1239,3F4BS@33958,4HHQT@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain GOKNOHPG_01999 891391.LAC30SC_05375 3.5e-132 477.6 Lactobacillaceae 2.4.2.3 ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01876,R02484,R08229 RC00063 ko00000,ko00001,ko01000 Bacteria 1TQ71@1239,3F3UX@33958,4IRA8@91061,COG2820@1,COG2820@2 NA|NA|NA F Phosphorylase superfamily GOKNOHPG_02000 405566.lhv_1123 1.1e-74 285.8 Lactobacillaceae cdd GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009972,GO:0009987,GO:0016020,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019856,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042455,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046108,GO:0046109,GO:0046112,GO:0046131,GO:0046132,GO:0046133,GO:0046134,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0072529,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 2.4.2.4,3.5.4.5 ko:K00758,ko:K01489 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 R01570,R01878,R02484,R02485,R08221,R08222,R08230 RC00063,RC00074,RC00514 ko00000,ko00001,ko01000 Bacteria 1V7IK@1239,3FC88@33958,4HMND@91061,COG0295@1,COG0295@2 NA|NA|NA F Cytidine and deoxycytidylate deaminase zinc-binding region GOKNOHPG_02002 405566.lhv_1122 6.1e-79 300.1 Lactobacillaceae Bacteria 1V125@1239,3F5TK@33958,4HFVJ@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain GOKNOHPG_02003 891391.LAC30SC_05360 1.8e-56 225.3 Lactobacillaceae Bacteria 1U67S@1239,29P75@1,30A58@2,3F79M@33958,4IFYB@91061 NA|NA|NA GOKNOHPG_02004 405566.lhv_1120 4.6e-134 483.8 Lactobacillaceae Bacteria 1VDYG@1239,2C6BP@1,32SQP@2,3F5TH@33958,4HS7C@91061 NA|NA|NA GOKNOHPG_02005 405566.lhv_1119 8.3e-205 719.5 Lactobacillaceae ko:K08152 ko00000,ko02000 2.A.1.2 Bacteria 1W01A@1239,3F4S8@33958,4HZ1U@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily GOKNOHPG_02006 326425.lhe_1014 1.7e-102 378.6 Lactobacillaceae Bacteria 1U5RF@1239,2A1GN@1,30PQ9@2,3F6DA@33958,4IFFK@91061 NA|NA|NA GOKNOHPG_02007 891391.LAC30SC_05250 7.9e-134 483.0 Lactobacillaceae Bacteria 1V3AX@1239,3F4YX@33958,4HVK3@91061,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family GOKNOHPG_02008 1423748.BALB01000009_gene1058 1.6e-55 222.2 Lactobacillaceae Bacteria 1U5S0@1239,29NX2@1,309V6@2,3F6ET@33958,4IFGA@91061 NA|NA|NA GOKNOHPG_02009 326425.lhe_1011 1.8e-73 282.0 Lactobacillaceae Bacteria 1U6XC@1239,2C5CP@1,30ANW@2,3F8NS@33958,4IGRM@91061 NA|NA|NA GOKNOHPG_02010 405566.lhv_1114 1.9e-57 228.4 Lactobacillaceae ypaA ko:K08987 ko00000 Bacteria 1VAVU@1239,3F7NA@33958,4HQHN@91061,COG3759@1,COG3759@2 NA|NA|NA S Protein of unknown function (DUF1304) GOKNOHPG_02011 405566.lhv_1113 5.1e-67 261.2 Lactobacillaceae Bacteria 1VKFR@1239,3F4TV@33958,4HRQ4@91061,COG3595@1,COG3595@2 NA|NA|NA S Putative adhesin GOKNOHPG_02012 405566.lhv_1112 2.7e-291 1007.3 Lactobacillaceae Bacteria 1TSRV@1239,3F46B@33958,4HCIZ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC-type multidrug transport system, ATPase and permease components GOKNOHPG_02013 405566.lhv_1111 9.3e-292 1008.8 Lactobacillaceae Bacteria 1TSRV@1239,3F514@33958,4HCIZ@91061,COG1132@1,COG1132@2 NA|NA|NA P ABC transporter GOKNOHPG_02014 1423748.BALB01000009_gene1052 1.2e-58 232.3 Lactobacillaceae Bacteria 1U5Z5@1239,29P12@1,309Z7@2,3F6QZ@33958,4IFN5@91061 NA|NA|NA GOKNOHPG_02015 1423748.BALB01000009_gene1051 6.2e-86 323.6 Lactobacillaceae fic ko:K04095 ko00000,ko03036 Bacteria 1VK13@1239,3F711@33958,4IQYB@91061,COG2184@1,COG2184@2 NA|NA|NA D Fic/DOC family GOKNOHPG_02016 326425.lhe_1007 4.3e-255 886.7 Lactobacillaceae pepT2 3.4.11.14,3.4.11.4 ko:K01258,ko:K01263 ko00000,ko01000,ko01002 Bacteria 1TP3A@1239,3F45V@33958,4HAZE@91061,COG2195@1,COG2195@2 NA|NA|NA E Cleaves the N-terminal amino acid of tripeptides GOKNOHPG_02017 405566.lhv_1107 2.3e-235 821.2 Lactobacillaceae mepA ko:K18908 M00705 ko00000,ko00002,ko01504,ko02000 2.A.66.1.13 Bacteria 1TPFM@1239,3F3KX@33958,4HEHY@91061,COG0534@1,COG0534@2 NA|NA|NA V MATE efflux family protein GOKNOHPG_02018 405566.lhv_1106 5.3e-231 806.6 Lactobacillaceae Bacteria 1TQMA@1239,3F3QW@33958,4HDTN@91061,COG1376@1,COG1376@2 NA|NA|NA S Putative peptidoglycan binding domain GOKNOHPG_02019 326425.lhe_1004 2e-92 345.1 Lactobacillaceae ko:K16923 M00582 ko00000,ko00002,ko02000 3.A.1.28 Bacteria 1V52B@1239,3F4W9@33958,4HKM2@91061,COG4720@1,COG4720@2 NA|NA|NA S ECF-type riboflavin transporter, S component GOKNOHPG_02020 326425.lhe_1003 2.4e-150 538.1 Lactobacillaceae pdxK 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TRCR@1239,3F3V7@33958,4HHME@91061,COG2240@1,COG2240@2 NA|NA|NA H Phosphomethylpyrimidine kinase GOKNOHPG_02021 326425.lhe_1002 6.5e-204 716.5 Lactobacillaceae pbpX1 Bacteria 1U52D@1239,3F440@33958,4IETU@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase GOKNOHPG_02022 405566.lhv_1102 1e-105 389.4 Lactobacillaceae lacA 2.3.1.79 ko:K00661 ko00000,ko01000 Bacteria 1V06U@1239,3FBEW@33958,4IPZB@91061,COG0110@1,COG0110@2 NA|NA|NA S Transferase hexapeptide repeat GOKNOHPG_02023 405566.lhv_1101 5.2e-113 413.7 Lactobacillaceae 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1V7XD@1239,3FBEV@33958,4IPZ9@91061,COG0671@1,COG0671@2 NA|NA|NA I Acid phosphatase homologues GOKNOHPG_02024 326425.lhe_0999 7.8e-79 299.7 Lactobacillaceae Bacteria 1V465@1239,3F7H7@33958,4HN5X@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin GOKNOHPG_02025 326425.lhe_0998 0.0 1170.2 Lactobacillaceae recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPN5@1239,3F4PY@33958,4H9QP@91061,COG0514@1,COG0514@2 NA|NA|NA L ATP-dependent DNA helicase RecQ GOKNOHPG_02026 1423748.BALB01000009_gene1037 3.2e-52 211.1 Lactobacillaceae ktrB ko:K03498 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1TQ4S@1239,3F5BE@33958,4H9ME@91061,COG0168@1,COG0168@2 NA|NA|NA P Potassium uptake protein GOKNOHPG_02027 1423754.BALY01000027_gene849 1.5e-52 212.2 Lactobacillaceae ktrB ko:K03498 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1TQ4S@1239,3F5BE@33958,4H9ME@91061,COG0168@1,COG0168@2 NA|NA|NA P Potassium uptake protein GOKNOHPG_02028 1423748.BALB01000009_gene1037 1.9e-29 134.8 Lactobacillaceae ktrB ko:K03498 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1TQ4S@1239,3F5BE@33958,4H9ME@91061,COG0168@1,COG0168@2 NA|NA|NA P Potassium uptake protein GOKNOHPG_02029 1423748.BALB01000009_gene1036 4.3e-113 414.1 Lactobacillaceae ktrA ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1TQ9H@1239,3F5G0@33958,4HBPH@91061,COG0569@1,COG0569@2 NA|NA|NA P domain protein GOKNOHPG_02030 326425.lhe_0997 7.9e-246 855.9 Lactobacillaceae ynbB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 4.4.1.1 ko:K01758 ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230 M00338 R00782,R01001,R02408,R04770,R04930,R09366 RC00056,RC00069,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TQ88@1239,3F3PU@33958,4HAF5@91061,COG4100@1,COG4100@2 NA|NA|NA P aluminum resistance GOKNOHPG_02031 326425.lhe_0996 3.2e-189 667.5 Lactobacillaceae yaaO 4.1.1.17,4.1.1.19 ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00133,M00134 R00566,R00670 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 1TNZ9@1239,3F3TV@33958,4HBGC@91061,COG1982@1,COG1982@2 NA|NA|NA E Orn/Lys/Arg decarboxylase, C-terminal domain GOKNOHPG_02032 326425.lhe_0996 3.5e-199 700.7 Lactobacillaceae yaaO 4.1.1.17,4.1.1.19 ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00133,M00134 R00566,R00670 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 1TNZ9@1239,3F3TV@33958,4HBGC@91061,COG1982@1,COG1982@2 NA|NA|NA E Orn/Lys/Arg decarboxylase, C-terminal domain GOKNOHPG_02033 405566.lhv_1092 1.2e-109 402.5 Lactobacillaceae Bacteria 1UZVA@1239,3F4KP@33958,4HH09@91061,COG3039@1,COG3039@2 NA|NA|NA L An automated process has identified a potential problem with this gene model GOKNOHPG_02034 1423767.BALU01000008_gene600 2e-272 944.5 Lactobacillaceae ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1UYSD@1239,3F48U@33958,4IPMN@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease GOKNOHPG_02035 1423748.BALB01000009_gene1032 1.5e-15 87.8 Lactobacillaceae XK26_02160 Bacteria 1TR2Q@1239,3F66T@33958,4HHXT@91061,COG5015@1,COG5015@2 NA|NA|NA C Pyridoxamine 5'-phosphate oxidase GOKNOHPG_02036 326425.lhe_0989 2.9e-63 247.7 Lactobacillaceae crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 1VM30@1239,3F8A8@33958,4HRC4@91061,COG0239@1,COG0239@2 NA|NA|NA U Important for reducing fluoride concentration in the cell, thus reducing its toxicity GOKNOHPG_02037 326425.lhe_0988 4.6e-64 250.4 Lactobacillaceae crcB ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 1U4G6@1239,3F6R4@33958,4IE88@91061,COG0239@1,COG0239@2 NA|NA|NA U Important for reducing fluoride concentration in the cell, thus reducing its toxicity GOKNOHPG_02038 405566.lhv_1082 9.9e-149 532.7 Lactobacillaceae xerD ko:K04763 ko00000,ko03036 Bacteria 1UFH8@1239,3F3KV@33958,4IES1@91061,COG4974@1,COG4974@2 NA|NA|NA L Phage integrase, N-terminal SAM-like domain GOKNOHPG_02039 525365.HMPREF0548_0270 7.1e-36 157.1 Lactobacillaceae birA 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 Bacteria 1TQCU@1239,3F5HY@33958,4HB60@91061,COG0340@1,COG0340@2 NA|NA|NA H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor GOKNOHPG_02040 585524.HMPREF0493_0223 2.7e-116 424.9 Lactobacillaceae fabI GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPVD@1239,3F4AQ@33958,4H9YN@91061,COG0623@1,COG0623@2 NA|NA|NA I Enoyl- acyl-carrier-protein reductase NADH GOKNOHPG_02041 585524.HMPREF0493_0222 4e-94 350.9 Lactobacillaceae accA 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHNS@1239,3F496@33958,4HA4C@91061,COG0825@1,COG0825@2 NA|NA|NA I alpha subunit GOKNOHPG_02042 585524.HMPREF0493_0221 1.1e-69 269.2 Lactobacillaceae accD 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4U@1239,3F3T6@33958,4HAI7@91061,COG0777@1,COG0777@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA GOKNOHPG_02046 405566.lhv_1079 2.6e-174 617.8 Lactobacillaceae lacX 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 1U26T@1239,3F3KT@33958,4HA4J@91061,COG2017@1,COG2017@2 NA|NA|NA G Aldose 1-epimerase GOKNOHPG_02047 326425.lhe_0984 1.7e-233 815.1 Lactobacillaceae hslU GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03667 ko00000,ko03110 Bacteria 1TPKQ@1239,3F3WB@33958,4HA83@91061,COG1220@1,COG1220@2 NA|NA|NA O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis GOKNOHPG_02048 326425.lhe_0983 3e-90 337.8 Lactobacillaceae hslV GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 ko:K01419 ko00000,ko01000,ko01002 Bacteria 1TPXK@1239,3F4HS@33958,4H9PD@91061,COG5405@1,COG5405@2 NA|NA|NA O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery GOKNOHPG_02049 326425.lhe_0982 4.8e-168 597.0 Lactobacillaceae xerC ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 1TQRG@1239,3FBHU@33958,4IQMI@91061,COG4974@1,COG4974@2 NA|NA|NA D Phage integrase, N-terminal SAM-like domain GOKNOHPG_02050 326425.lhe_0981 1.5e-247 861.7 Lactobacillaceae trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 ko00000,ko01000,ko03016,ko03036 Bacteria 1TP67@1239,3F3WW@33958,4HB27@91061,COG1206@1,COG1206@2 NA|NA|NA J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs GOKNOHPG_02051 326425.lhe_0980 0.0 1317.4 Lactobacillaceae topA 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria 1TPUS@1239,3F3VS@33958,4HA6C@91061,COG0550@1,COG0550@2 NA|NA|NA L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone GOKNOHPG_02052 326425.lhe_0979 2.8e-154 551.2 Lactobacillaceae dprA GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 ko:K04096 ko00000 Bacteria 1TPP7@1239,3F41U@33958,4HGWM@91061,COG0758@1,COG0758@2 NA|NA|NA LU DNA protecting protein DprA GOKNOHPG_02053 405566.lhv_1072 3.7e-134 484.2 Lactobacillaceae rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1V1D6@1239,3F3JC@33958,4HB7M@91061,COG0164@1,COG0164@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids GOKNOHPG_02054 405566.lhv_1071 3e-156 557.8 Lactobacillaceae ylqF GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 ko:K14540 ko00000,ko03009 Bacteria 1TQGK@1239,3F3MI@33958,4HA4D@91061,COG1161@1,COG1161@2 NA|NA|NA S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity GOKNOHPG_02055 405566.lhv_1070 1.6e-275 954.9 Lactobacillaceae yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 1TR4G@1239,3F42V@33958,4HBJR@91061,COG0025@1,COG0025@2 NA|NA|NA P Sodium proton antiporter GOKNOHPG_02056 326425.lhe_0975 9.3e-36 155.6 Lactobacillaceae yozE Bacteria 1VFI4@1239,3F7ZP@33958,4HR7P@91061,COG4479@1,COG4479@2 NA|NA|NA S Belongs to the UPF0346 family GOKNOHPG_02057 326425.lhe_0974 4.8e-146 523.9 Lactobacillaceae DegV Bacteria 1TRM7@1239,3FC90@33958,4HBIR@91061,COG1307@1,COG1307@2 NA|NA|NA S Uncharacterised protein, DegV family COG1307 GOKNOHPG_02058 326425.lhe_0973 9.7e-113 412.9 Lactobacillaceae hlyIII ko:K11068 ko00000,ko02042 Bacteria 1TSFK@1239,3F578@33958,4HAT2@91061,COG1272@1,COG1272@2 NA|NA|NA S protein, hemolysin III GOKNOHPG_02059 405566.lhv_1066 8.6e-226 789.3 Lactobacillaceae cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 1TQ2A@1239,3F3VH@33958,4HB2W@91061,COG0617@1,COG0617@2 NA|NA|NA J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate GOKNOHPG_02060 326425.lhe_0971 5.2e-159 567.0 Lactobacillaceae ypjC Bacteria 1TR9J@1239,3FC4M@33958,4H9N6@91061,COG1284@1,COG1284@2 NA|NA|NA S Uncharacterised 5xTM membrane BCR, YitT family COG1284 GOKNOHPG_02061 525365.HMPREF0548_1576 1.1e-50 206.1 Bacilli Z012_06740 Bacteria 1TZWX@1239,4HGN9@91061,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family GOKNOHPG_02062 326425.lhe_0381 0.0 1182.5 Lactobacillaceae pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 ko:K08602 ko00000,ko01000,ko01002 Bacteria 1TP4P@1239,3F4E5@33958,4HA7X@91061,COG1164@1,COG1164@2 NA|NA|NA E oligoendopeptidase F GOKNOHPG_02063 405566.lhv_1834 5.6e-212 743.4 Lactobacillaceae brpA Bacteria 1TR1B@1239,3F3MQ@33958,4HA09@91061,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-like function transcriptional attenuator common domain protein GOKNOHPG_02064 1423748.BALB01000012_gene1196 1.3e-114 419.1 Lactobacillaceae ko:K07150 ko00000 Bacteria 1U5PM@1239,3F56J@33958,4HEHT@91061,COG1811@1,COG1811@2 NA|NA|NA S Protein of unknown function (DUF554) GOKNOHPG_02065 326425.lhe_0384 9.9e-100 369.4 Lactobacillaceae rimL ko:K03817 ko00000,ko01000,ko03009 Bacteria 1V3NE@1239,3F6YW@33958,4HG1N@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain GOKNOHPG_02066 891391.LAC30SC_09505 1.6e-53 215.3 Lactobacillaceae Bacteria 1U5V0@1239,29NYN@1,309WR@2,3F6IV@33958,4IFIN@91061 NA|NA|NA GOKNOHPG_02067 405566.lhv_1829 2.1e-288 997.7 Lactobacillaceae ko:K06158 ko00000,ko03012 Bacteria 1TPAX@1239,3FC7X@33958,4HC58@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter GOKNOHPG_02068 405566.lhv_1828 4.8e-137 493.8 Lactobacillaceae thrE Bacteria 1TSE8@1239,3F4XE@33958,4HBW1@91061,COG2966@1,COG2966@2 NA|NA|NA S Putative threonine/serine exporter GOKNOHPG_02069 405566.lhv_1827 1.7e-79 302.0 Lactobacillaceae Bacteria 1V6P0@1239,3F63I@33958,4HJ1Y@91061,COG3610@1,COG3610@2 NA|NA|NA S Threonine/Serine exporter, ThrE GOKNOHPG_02070 326425.lhe_0389 1.3e-142 512.3 Lactobacillaceae yvpB Bacteria 1V3XE@1239,3F4HZ@33958,4HJBT@91061,COG4990@1,COG4990@2 NA|NA|NA S Peptidase_C39 like family GOKNOHPG_02071 326425.lhe_1829 3.6e-160 570.9 Lactobacillaceae prsA 5.2.1.8 ko:K02597,ko:K07533 ko00000,ko01000,ko03110 Bacteria 1VT0K@1239,3F4RW@33958,4I4BP@91061,COG0760@1,COG0760@2 NA|NA|NA M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins GOKNOHPG_02072 1423816.BACQ01000055_gene2101 5e-196 690.3 Lactobacillaceae ko:K07493 ko00000 Bacteria 1TP4C@1239,3F4RA@33958,4HAXJ@91061,COG3328@1,COG3328@2 NA|NA|NA L Transposase GOKNOHPG_02073 326425.lhe_1828 0.0 3367.0 Lactobacillaceae prtS 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652,ko:K17734 ko00000,ko01000,ko01002,ko03110 Bacteria 1TPH1@1239,3F3M5@33958,4HBQH@91061,COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family GOKNOHPG_02074 272621.LBA1710 1.2e-83 316.6 Lactobacillaceae pulA 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 R02111 ko00000,ko00001,ko01000 CBM48,GH13 Bacteria 1TP3M@1239,3F4C2@33958,4HBP5@91061,COG1523@1,COG1523@2 NA|NA|NA G belongs to the glycosyl hydrolase 13 family GOKNOHPG_02075 1033837.WANG_0860 7.4e-22 109.0 Lactobacillaceae Bacteria 1U7X0@1239,2BN97@1,32GWQ@2,3FA9Y@33958,4IHUC@91061 NA|NA|NA GOKNOHPG_02076 1033837.WANG_0859 2.9e-54 217.6 Lactobacillaceae 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1V3Z1@1239,3F555@33958,4IEZK@91061,COG0584@1,COG0584@2 NA|NA|NA C Glycerophosphoryl diester phosphodiesterase family GOKNOHPG_02077 1033837.WANG_0859 1.6e-88 332.0 Lactobacillaceae 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1V3Z1@1239,3F555@33958,4IEZK@91061,COG0584@1,COG0584@2 NA|NA|NA C Glycerophosphoryl diester phosphodiesterase family GOKNOHPG_02078 1033837.WANG_0858 1.6e-65 255.4 Lactobacillaceae 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003 GT2 Bacteria 1VP71@1239,3F73E@33958,4HSE0@91061,COG2246@1,COG2246@2 NA|NA|NA S GtrA-like protein GOKNOHPG_02079 1033837.WANG_0857 2.1e-171 608.2 Lactobacillaceae yfdH ko:K12999,ko:K20534 ko00000,ko01000,ko01003,ko01005,ko02000 4.D.2.1.9 GT2 Bacteria 1TPR3@1239,3FBT4@33958,4HC2Z@91061,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase like family 2 GOKNOHPG_02080 1033837.WANG_0856 1.1e-127 463.0 Lactobacillaceae Bacteria 1UZCF@1239,3F48H@33958,4HDPY@91061,COG4485@1,COG4485@2 NA|NA|NA S Bacterial membrane protein, YfhO GOKNOHPG_02081 1033837.WANG_0317 5.6e-201 706.8 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TRNY@1239,3F55P@33958,4HBKP@91061,COG0675@1,COG0675@2 NA|NA|NA L transposase, IS605 OrfB family GOKNOHPG_02082 405566.lhv_0207 2.7e-154 551.2 Lactobacillaceae Bacteria 1UGQV@1239,2A3XC@1,30SFQ@2,3F5YM@33958,4IF8A@91061 NA|NA|NA S Fibronectin type III domain GOKNOHPG_02083 1423748.BALB01000008_gene938 1e-240 839.0 Lactobacillaceae tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iAF1260.b1637,iBWG_1329.BWG_1452,iECDH10B_1368.ECDH10B_1771,iECDH1ME8569_1439.ECDH1ME8569_1581,iECH74115_1262.ECH74115_2349,iECIAI39_1322.ECIAI39_1418,iECNA114_1301.ECNA114_1685,iECO103_1326.ECO103_1778,iECO111_1330.ECO111_2107,iECO26_1355.ECO26_2366,iECSE_1348.ECSE_1760,iECSF_1327.ECSF_1500,iECSP_1301.ECSP_2202,iECUMN_1333.ECUMN_1928,iECW_1372.ECW_m1805,iECs_1301.ECs2346,iEKO11_1354.EKO11_2137,iETEC_1333.ETEC_1672,iEcDH1_1363.EcDH1_2003,iEcE24377_1341.EcE24377A_1847,iEcHS_1320.EcHS_A1713,iEcSMS35_1347.EcSMS35_1562,iEcolC_1368.EcolC_1992,iJO1366.b1637,iSFV_1184.SFV_1654,iSF_1195.SF1662,iSSON_1240.SSON_1519,iSbBS512_1146.SbBS512_E1829,iUMNK88_1353.UMNK88_2097,iWFL_1372.ECW_m1805,iY75_1357.Y75_RS08585 Bacteria 1TPGN@1239,3F48J@33958,4H9YV@91061,COG0162@1,COG0162@2 NA|NA|NA J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) GOKNOHPG_02084 326425.lhe_1879 1.5e-27 128.3 Lactobacillaceae Bacteria 1U655@1239,2BZTJ@1,30A3I@2,3F72R@33958,4IFUX@91061 NA|NA|NA GOKNOHPG_02085 405566.lhv_1773 0.0 1092.0 Lactobacillaceae ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TR2D@1239,3F45H@33958,4HAZG@91061,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family GOKNOHPG_02086 405566.lhv_1774 4.8e-134 483.8 Lactobacillaceae cysA ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TNZG@1239,3F3MG@33958,4H9UT@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein GOKNOHPG_02087 405566.lhv_1775 5.7e-236 823.2 Lactobacillaceae Bacteria 1V6D3@1239,3F4ZG@33958,4IPQE@91061,COG4640@1,COG4640@2 NA|NA|NA S response to antibiotic GOKNOHPG_02088 326425.lhe_0445 2.9e-122 444.5 Lactobacillaceae Bacteria 1U591@1239,29NN1@1,309JZ@2,3F57G@33958,4IF0C@91061 NA|NA|NA GOKNOHPG_02089 405566.lhv_2920 3.2e-15 86.7 Lactobacillaceae Bacteria 1U70J@1239,29PT6@1,30ARD@2,3F8TF@33958,4IGUW@91061 NA|NA|NA GOKNOHPG_02090 326425.lhe_0441 6.6e-187 659.8 Lactobacillaceae ansA 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 R00485 RC00010,RC02798 ko00000,ko00001,ko01000 Bacteria 1TPP9@1239,3FCC6@33958,4HD98@91061,COG0252@1,COG0252@2 NA|NA|NA EJ L-asparaginase, type I GOKNOHPG_02091 1423748.BALB01000015_gene1397 3.5e-98 364.4 Lactobacillaceae glvR ko:K03481 ko00000,ko03000 Bacteria 1TR3Z@1239,3FBJI@33958,4IQVZ@91061,COG1737@1,COG1737@2 NA|NA|NA K Helix-turn-helix domain, rpiR family GOKNOHPG_02092 326425.lhe_0439 8.2e-96 356.3 Lactobacillaceae Bacteria 1U63K@1239,2A3Q0@1,30S7H@2,3F6YD@33958,4IFT0@91061 NA|NA|NA GOKNOHPG_02093 1423748.BALB01000015_gene1401 8.4e-27 125.9 Lactobacillaceae 3.2.2.20 ko:K01246,ko:K06977 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V7GR@1239,3F44B@33958,4HJ11@91061,COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase GOKNOHPG_02094 326425.lhe_1881 3.1e-81 307.8 Lactobacillaceae Bacteria 1UGQV@1239,2A3XC@1,30SFQ@2,3F5YM@33958,4IF8A@91061 NA|NA|NA S Fibronectin type III domain GOKNOHPG_02095 326425.lhe_1882 0.0 1911.3 Lactobacillaceae XK27_08315 Bacteria 1TQYQ@1239,3F3NY@33958,4HBY6@91061,COG1368@1,COG1368@2 NA|NA|NA M Sulfatase GOKNOHPG_02096 326425.lhe_1883 4.8e-111 407.1 Lactobacillaceae plsY 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1VAFC@1239,3F5HQ@33958,4HMJZ@91061,COG0344@1,COG0344@2 NA|NA|NA I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP GOKNOHPG_02097 405566.lhv_0204 1.2e-194 685.6 Lactobacillaceae brpA Bacteria 1TR1B@1239,3F3MQ@33958,4HA09@91061,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-like function transcriptional attenuator common domain protein GOKNOHPG_02098 405566.lhv_0203 5.3e-101 373.6 Lactobacillaceae Bacteria 1U5EB@1239,3F5Q4@33958,4IF5R@91061,COG2017@1,COG2017@2 NA|NA|NA G Aldose 1-epimerase GOKNOHPG_02099 405566.lhv_0202 1.4e-107 395.6 Lactobacillaceae pcp GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.19.3 ko:K01304 ko00000,ko01000,ko01002 Bacteria 1TRRX@1239,3F46I@33958,4HCIJ@91061,COG2039@1,COG2039@2 NA|NA|NA O Removes 5-oxoproline from various penultimate amino acid residues except L-proline GOKNOHPG_02100 326425.lhe_1887 9.3e-132 476.1 Lactobacillaceae gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1TQFP@1239,3F3SK@33958,4HAW7@91061,COG0588@1,COG0588@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate GOKNOHPG_02101 748671.LCRIS_01642 2.8e-20 104.4 Lactobacillaceae ybbH_2 ko:K03481 ko00000,ko03000 Bacteria 1TR0N@1239,3F42G@33958,4HB9E@91061,COG1737@1,COG1737@2 NA|NA|NA K rpiR family GOKNOHPG_02102 405566.lhv_2079 5.1e-116 423.7 Lactobacillaceae dak 2.7.1.74,2.7.1.76 ko:K00893,ko:K10353 ko00230,ko00240,ko01100,map00230,map00240,map01100 R00185,R01666,R02089 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TPJ1@1239,3F488@33958,4HA9N@91061,COG1428@1,COG1428@2 NA|NA|NA F deoxynucleoside kinase GOKNOHPG_02103 326425.lhe_1906 4.5e-126 457.2 Lactobacillaceae dgk 2.7.1.74,2.7.1.76 ko:K00893,ko:K10353 ko00230,ko00240,ko01100,map00230,map00240,map01100 R00185,R01666,R02089 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TPJ1@1239,3F488@33958,4HA9N@91061,COG1428@1,COG1428@2 NA|NA|NA F deoxynucleoside kinase GOKNOHPG_02104 326425.lhe_1907 4.2e-144 517.3 Lactobacillaceae cof Bacteria 1TSGF@1239,3F57T@33958,4HHWU@91061,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase GOKNOHPG_02105 405566.lhv_2082 1.7e-230 805.1 Lactobacillaceae pbuG ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 1TQC6@1239,3F44D@33958,4HANG@91061,COG2252@1,COG2252@2 NA|NA|NA S permease GOKNOHPG_02106 1423767.BALU01000001_gene1588 3.7e-200 704.1 Lactobacillaceae ko:K07133 ko00000 Bacteria 1TP7X@1239,3F51K@33958,4HCSJ@91061,COG1373@1,COG1373@2 NA|NA|NA S cog cog1373 GOKNOHPG_02107 326425.lhe_1910 1.1e-59 235.7 Lactobacillaceae Bacteria 1V05W@1239,3F4R7@33958,4HSX6@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance GOKNOHPG_02108 326425.lhe_1911 9.1e-229 799.3 Lactobacillaceae pbuG ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 1TQC6@1239,3F44D@33958,4HANG@91061,COG2252@1,COG2252@2 NA|NA|NA S permease GOKNOHPG_02109 326425.lhe_1127 6.6e-76 290.0 Lactobacillaceae yoaK Bacteria 1V1VQ@1239,3F5F5@33958,4HM4F@91061,COG3619@1,COG3619@2 NA|NA|NA S Protein of unknown function (DUF1275) GOKNOHPG_02110 748671.LCRIS_01141 7.1e-18 95.5 Lactobacillaceae Bacteria 1VENK@1239,3F7EK@33958,4HNKV@91061,COG2261@1,COG2261@2 NA|NA|NA S Transglycosylase associated protein GOKNOHPG_02111 1423748.BALB01000007_gene907 4.5e-86 323.9 Lactobacillaceae ko:K07273 ko00000 Bacteria 1VF8D@1239,3F4U9@33958,4HX0U@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 GOKNOHPG_02112 1423748.BALB01000007_gene907 9e-17 92.0 Lactobacillaceae ko:K07273 ko00000 Bacteria 1VF8D@1239,3F4U9@33958,4HX0U@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 GOKNOHPG_02113 405566.lhv_2516 5.8e-53 213.4 Lactobacillaceae Bacteria 1TV1H@1239,2DINK@1,303QK@2,3F7U7@33958,4HYBN@91061 NA|NA|NA GOKNOHPG_02114 405566.lhv_1249 1.5e-109 402.1 Lactobacillaceae XK27_00160 Bacteria 1V5Q4@1239,29N5D@1,30939@2,3F5S8@33958,4HHUF@91061 NA|NA|NA S Domain of unknown function (DUF5052) GOKNOHPG_02115 405566.lhv_2517 3.9e-84 317.4 Lactobacillaceae adk 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1V7AW@1239,3F6PA@33958,4HH8A@91061,COG0563@1,COG0563@2 NA|NA|NA F topology modulation protein GOKNOHPG_02116 1423748.BALB01000007_gene904 5.3e-67 260.4 Lactobacillaceae Bacteria 1U5N3@1239,29EME@1,301JC@2,3F67R@33958,4IFCU@91061 NA|NA|NA GOKNOHPG_02117 326425.lhe_1133 7.6e-205 719.5 Lactobacillaceae xerS GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 ko:K04763 ko00000,ko03036 Bacteria 1TPQB@1239,3F3P9@33958,4HANE@91061,COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family GOKNOHPG_02118 1423815.BACR01000049_gene2340 7.3e-51 207.2 Lactobacillaceae Bacteria 1U4W9@1239,2DHKX@1,30063@2,3F5EU@33958,4IEM0@91061 NA|NA|NA GOKNOHPG_02119 1423767.BALU01000003_gene1092 3.1e-124 451.8 Lactobacillaceae Bacteria 1U59E@1239,29DXA@1,300V7@2,3F59A@33958,4IF0P@91061 NA|NA|NA S SLAP domain GOKNOHPG_02120 1133569.AHYZ01000024_gene414 3.4e-49 200.7 Lactobacillaceae ko:K19158 ko00000,ko01000,ko02048 Bacteria 1VAM5@1239,3F86X@33958,4HRX3@91061,COG4115@1,COG4115@2 NA|NA|NA S YoeB-like toxin of bacterial type II toxin-antitoxin system GOKNOHPG_02121 1400520.LFAB_17430 1.7e-38 164.9 Lactobacillaceae Bacteria 1U63Q@1239,2DKNJ@1,30A2H@2,3F6YR@33958,4IFT5@91061 NA|NA|NA S Antitoxin component of a toxin-antitoxin (TA) module GOKNOHPG_02122 60520.HR47_14815 4e-107 394.0 Lactobacillaceae ko:K04763 ko00000,ko03036 Bacteria 1V2RX@1239,3F4SP@33958,4IEJ7@91061,COG0582@1,COG0582@2 NA|NA|NA L Integrase GOKNOHPG_02123 1138822.PL11_10075 2.9e-27 127.1 Bacilli repA Bacteria 1TQXM@1239,2DBC6@1,2Z8BZ@2,4IQUN@91061 NA|NA|NA S Replication initiator protein A (RepA) N-terminus GOKNOHPG_02124 405566.lhv_1740 3.1e-150 538.1 Lactobacillaceae Bacteria 1U58Z@1239,29NMZ@1,309JX@2,3F573@33958,4IF0A@91061 NA|NA|NA GOKNOHPG_02125 326425.lhe_0479 3.3e-261 907.1 Lactobacillaceae gabD 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4S@1239,3F47F@33958,4H9MF@91061,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family GOKNOHPG_02126 326425.lhe_0480 2e-126 458.4 Lactobacillaceae hipB GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K15773 ko00000,ko02048,ko03000 Bacteria 1VBK2@1239,3FBE7@33958,4HCZ9@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix GOKNOHPG_02127 405566.lhv_1737 1.4e-152 545.4 Lactobacillaceae Bacteria 1VEC5@1239,3F50A@33958,4HKY6@91061,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold GOKNOHPG_02128 405566.lhv_1736 4.8e-108 397.1 Lactobacillaceae yjbF Bacteria 1V7NH@1239,3F3SV@33958,4HIU5@91061,COG0398@1,COG0398@2 NA|NA|NA S SNARE associated Golgi protein GOKNOHPG_02129 405566.lhv_1735 6e-97 360.1 Lactobacillaceae Bacteria 1V49W@1239,3F5A6@33958,4HHAP@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain GOKNOHPG_02130 405566.lhv_1734 3.1e-245 854.0 Lactobacillaceae serS GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF987.Gmet_3528,iSDY_1059.SDY_2368 Bacteria 1TP4W@1239,3F3M6@33958,4H9Y4@91061,COG0172@1,COG0172@2 NA|NA|NA J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) GOKNOHPG_02131 405566.lhv_0620 5.1e-47 193.4 Lactobacillaceae Bacteria 1UZVA@1239,3F4KP@33958,4HH09@91061,COG3039@1,COG3039@2 NA|NA|NA L An automated process has identified a potential problem with this gene model GOKNOHPG_02132 1033837.WANG_1084 1.2e-25 121.7 Lactobacillaceae Bacteria 1UZVA@1239,3F4KP@33958,4HH09@91061,COG3039@1,COG3039@2 NA|NA|NA L An automated process has identified a potential problem with this gene model GOKNOHPG_02133 891391.LAC30SC_01195 2.9e-15 87.4 Lactobacillaceae Bacteria 1W1MV@1239,28QH1@1,2ZCZ3@2,3F7TZ@33958,4IG80@91061 NA|NA|NA GOKNOHPG_02134 1423748.BALB01000013_gene1290 0.0 1201.8 Lactobacillaceae lepA ko:K03596 ko05134,map05134 ko00000,ko00001 Bacteria 1TP0G@1239,3F3Z1@33958,4HASA@91061,COG0481@1,COG0481@2 NA|NA|NA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner GOKNOHPG_02135 326425.lhe_1261 1.9e-116 425.2 Lactobacillaceae srtA 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 1V83Z@1239,3F54V@33958,4HJV9@91061,COG3764@1,COG3764@2 NA|NA|NA M sortase family GOKNOHPG_02136 326425.lhe_1260 0.0 1483.8 Lactobacillaceae recJ ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPXE@1239,3F42C@33958,4H9UP@91061,COG0608@1,COG0608@2 NA|NA|NA L Single-stranded-DNA-specific exonuclease RecJ GOKNOHPG_02137 1423748.BALB01000013_gene1293 1.8e-95 355.1 Lactobacillaceae apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816,ko:K09685 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko03000,ko04147 Bacteria 1V1BV@1239,3F4DB@33958,4HFUA@91061,COG0503@1,COG0503@2 NA|NA|NA F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis GOKNOHPG_02138 405566.lhv_1064 3.6e-227 793.9 Lactobacillaceae Bacteria 1TT97@1239,3F3ND@33958,4HAIA@91061,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat protein GOKNOHPG_02139 1423748.BALB01000009_gene1004 8.8e-41 172.6 Lactobacillaceae hup ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 1V9XQ@1239,3F6YN@33958,4HKF2@91061,COG0776@1,COG0776@2 NA|NA|NA L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions GOKNOHPG_02140 326425.lhe_0968 2.4e-245 854.4 Lactobacillaceae der GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.399,1.1.1.95 ko:K00058,ko:K03977 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 Bacteria 1TPNM@1239,3F4V0@33958,4HAJ6@91061,COG1160@1,COG1160@2 NA|NA|NA S GTPase that plays an essential role in the late steps of ribosome biogenesis GOKNOHPG_02141 405566.lhv_1061 5.3e-207 726.9 Lactobacillaceae rpsA 1.17.7.4 ko:K02945,ko:K03527 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 Bacteria 1TQ9N@1239,3F4DQ@33958,4H9PX@91061,COG0539@1,COG0539@2 NA|NA|NA J Ribosomal protein S1 GOKNOHPG_02142 326425.lhe_0966 2.5e-113 414.8 Lactobacillaceae cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.17.7.4,2.5.1.19,2.7.1.26,2.7.4.25,2.7.7.2,6.3.2.1 ko:K00800,ko:K00945,ko:K02945,ko:K03527,ko:K03977,ko:K11753,ko:K13799 ko00240,ko00400,ko00410,ko00740,ko00770,ko00900,ko01100,ko01110,ko01130,ko01230,ko03010,map00240,map00400,map00410,map00740,map00770,map00900,map01100,map01110,map01130,map01230,map03010 M00022,M00052,M00096,M00119,M00125,M00178 R00158,R00161,R00512,R00549,R01665,R02473,R03460,R05884,R08210 RC00002,RC00017,RC00096,RC00141,RC00350,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03009,ko03011 iPC815.YPO1391,iSDY_1059.SDY_2348 Bacteria 1V3IA@1239,3F3W4@33958,4HFZE@91061,COG0283@1,COG0283@2 NA|NA|NA F Belongs to the cytidylate kinase family. Type 1 subfamily GOKNOHPG_02143 405566.lhv_1059 2.7e-26 125.2 Lactobacillaceae yocH Bacteria 1W2PN@1239,3F6G9@33958,4I0F8@91061,COG1388@1,COG1388@2 NA|NA|NA M Lysin motif GOKNOHPG_02144 405566.lhv_1057 6.1e-115 420.2 Lactobacillaceae Bacteria 1V4BW@1239,3F4HD@33958,4HHFT@91061,COG3601@1,COG3601@2 NA|NA|NA U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins GOKNOHPG_02145 326425.lhe_0963 1.1e-127 462.6 Lactobacillaceae rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.21,5.4.99.22 ko:K06178,ko:K06182,ko:K06183 ko00000,ko01000,ko03009 Bacteria 1TP68@1239,3F402@33958,4H9MU@91061,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family GOKNOHPG_02146 405566.lhv_1055 2.1e-103 381.7 Lactobacillaceae scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K06024 ko00000,ko03036 Bacteria 1V6HI@1239,3F5RN@33958,4HIQ0@91061,COG1386@1,COG1386@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves GOKNOHPG_02147 405566.lhv_1054 1.2e-129 469.2 Lactobacillaceae scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K05896 ko00000,ko03036 Bacteria 1TRW3@1239,3F4FS@33958,4HA6Q@91061,COG1354@1,COG1354@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves GOKNOHPG_02148 326425.lhe_0960 1.1e-59 235.7 Lactobacillaceae ribT ko:K02859 ko00000 Bacteria 1VAD7@1239,3F7QC@33958,4HKR2@91061,COG0454@1,COG0456@2 NA|NA|NA K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases GOKNOHPG_02149 326425.lhe_0959 4e-167 594.0 Lactobacillaceae xerD ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 1TQRG@1239,3F3V9@33958,4HAEX@91061,COG4974@1,COG4974@2 NA|NA|NA D recombinase XerD GOKNOHPG_02150 405566.lhv_1051 1.4e-167 595.5 Lactobacillaceae cvfB ko:K00243 ko00000 Bacteria 1TQ1Z@1239,3F44W@33958,4HDAZ@91061,COG2996@1,COG2996@2 NA|NA|NA S S1 domain GOKNOHPG_02151 326425.lhe_0957 0.0 1123.6 Lactobacillaceae pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009986,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0022607,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40,2.7.7.4 ko:K00873,ko:K00958 ko00010,ko00230,ko00261,ko00450,ko00620,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00261,map00450,map00620,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050,M00176,M00596 R00200,R00430,R00529,R01138,R01858,R02320,R04929 RC00002,RC00015,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iECO103_1326.ECO103_1819,iPC815.YPO2393 Bacteria 1TPGG@1239,3F3JU@33958,4H9VY@91061,COG0469@1,COG0469@2 NA|NA|NA G Belongs to the pyruvate kinase family GOKNOHPG_02152 405566.lhv_1049 3.3e-183 647.5 Lactobacillaceae pfkA GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 iYO844.BSU29190 Bacteria 1TPF4@1239,3F4CC@33958,4HAPN@91061,COG0205@1,COG0205@2 NA|NA|NA F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis GOKNOHPG_02153 326425.lhe_0955 0.0 2020.7 Lactobacillaceae dnaE 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPYG@1239,3F4AM@33958,4H9T3@91061,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase GOKNOHPG_02154 525365.HMPREF0548_1001 1.2e-21 108.6 Lactobacillaceae Bacteria 1U6JJ@1239,29PGH@1,30AEN@2,3F81E@33958,4IGC1@91061 NA|NA|NA S Protein of unknown function (DUF2929) GOKNOHPG_02155 326425.lhe_0953 1.4e-300 1038.1 Lactobacillaceae cpdB 3.1.3.6,3.1.4.16 ko:K01119 ko00230,ko00240,map00230,map00240 R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135 RC00078,RC00296 ko00000,ko00001,ko01000 Bacteria 1TPV2@1239,3F45U@33958,4HC2M@91061,COG0737@1,COG0737@2 NA|NA|NA F Belongs to the 5'-nucleotidase family GOKNOHPG_02156 1423748.BALB01000010_gene1125 7.6e-28 129.0 Lactobacillaceae rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VKMZ@1239,3F7ZT@33958,4HR2Q@91061,COG0333@1,COG0333@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL32 family GOKNOHPG_02157 326425.lhe_0951 6.2e-33 146.4 Lactobacillaceae yrvD ko:K08992 ko00000 Bacteria 1VIG5@1239,3F7IW@33958,4HP5V@91061,COG5416@1,COG5416@2 NA|NA|NA S Lipopolysaccharide assembly protein A domain GOKNOHPG_02158 405566.lhv_1044 1.1e-141 509.2 Lactobacillaceae XK27_05435 1.1.1.100 ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TSJ3@1239,3F41Y@33958,4HI3D@91061,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family GOKNOHPG_02159 405566.lhv_1043 3.9e-173 614.0 Lactobacillaceae rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 1TRGP@1239,3F4F1@33958,4HABM@91061,COG1234@1,COG1234@2 NA|NA|NA J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA GOKNOHPG_02160 405566.lhv_1042 0.0 1151.0 Lactobacillaceae oatA Bacteria 1TPTG@1239,3F3WT@33958,4HB7R@91061,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase GOKNOHPG_02161 326425.lhe_0947 2.5e-239 834.3 Lactobacillaceae obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043021,GO:0043022,GO:0043167,GO:0043168,GO:0043934,GO:0044424,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03979 ko00000,ko01000,ko03009 Bacteria 1TPX7@1239,3F4ZA@33958,4H9P8@91061,COG0536@1,COG0536@2 NA|NA|NA S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control GOKNOHPG_02162 405566.lhv_1040 0.0 1194.1 Lactobacillaceae uvrC ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TP4B@1239,3F3MY@33958,4H9QH@91061,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision GOKNOHPG_02163 1423748.BALB01000010_gene1118 9.9e-43 179.5 Lactobacillaceae dedA 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 1V2XQ@1239,3FBF1@33958,4IPZ1@91061,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein GOKNOHPG_02164 326425.lhe_0944 2.3e-238 831.2 Lactobacillaceae yfnA ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3F3QY@33958,4HA66@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid GOKNOHPG_02165 1423748.BALB01000010_gene1116 5.3e-41 173.3 Lactobacillaceae gyaR 1.1.1.26,2.7.1.165 ko:K00015,ko:K11529,ko:K15893 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346,M00532 R00717,R01388,R08572 RC00002,RC00031,RC00042,RC00428 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCX@1239,3F4Z6@33958,4HASY@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family GOKNOHPG_02166 525365.HMPREF0548_0990 3e-70 271.2 Lactobacillaceae gyaR 1.1.1.26,2.7.1.165 ko:K00015,ko:K11529,ko:K15893 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346,M00532 R00717,R01388,R08572 RC00002,RC00031,RC00042,RC00428 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCX@1239,3FB6D@33958,4HUAD@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family GOKNOHPG_02167 1423748.BALB01000010_gene1115 2.4e-14 83.6 Lactobacillaceae gyaR 1.1.1.26,2.7.1.165 ko:K00015,ko:K11529,ko:K15893 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346,M00532 R00717,R01388,R08572 RC00002,RC00031,RC00042,RC00428 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCX@1239,3F4Z6@33958,4HASY@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family GOKNOHPG_02168 1423748.BALB01000010_gene1114 4.9e-140 503.8 Lactobacillaceae yxeH Bacteria 1TR16@1239,3F55S@33958,4HCZ6@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase GOKNOHPG_02169 326425.lhe_0941 3.4e-132 477.6 Lactobacillaceae Bacteria 1TPM1@1239,3FB4S@33958,4HAG6@91061,COG0656@1,COG0656@2 NA|NA|NA S reductase GOKNOHPG_02170 405566.lhv_1017 1.8e-215 755.0 Lactobacillaceae coaBC 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPP3@1239,3F3XX@33958,4HAK8@91061,COG0452@1,COG0452@2 NA|NA|NA H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine GOKNOHPG_02171 405566.lhv_1015 1.6e-219 768.5 Lactobacillaceae patA 2.6.1.1 ko:K00812,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00525 R00355,R00694,R00734,R00896,R02433,R02619,R04467,R05052 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase GOKNOHPG_02172 405566.lhv_1014 0.0 1253.0 Lactobacillaceae aspS 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPCN@1239,3F4PE@33958,4HACD@91061,COG0173@1,COG0173@2 NA|NA|NA J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) GOKNOHPG_02173 405566.lhv_1013 6.8e-245 852.8 Lactobacillaceae hisS 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP3D@1239,3F3M3@33958,4HAM2@91061,COG0124@1,COG0124@2 NA|NA|NA J histidyl-tRNA synthetase GOKNOHPG_02174 405566.lhv_1012 1.1e-74 285.8 Lactobacillaceae dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K07560 ko00000,ko01000,ko03016 Bacteria 1V6GH@1239,3F6GK@33958,4HINN@91061,COG1490@1,COG1490@2 NA|NA|NA J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality GOKNOHPG_02175 326425.lhe_0935 0.0 1468.0 Lactobacillaceae relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 iHN637.CLJU_RS16615,iYO844.BSU27600 Bacteria 1TNYZ@1239,3F44F@33958,4HBX7@91061,COG0317@1,COG0317@2 NA|NA|NA KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance GOKNOHPG_02176 326425.lhe_0934 2.5e-59 234.6 Lactobacillaceae Bacteria 1U6F0@1239,29PCU@1,30AB2@2,3F7RV@33958,4IG6U@91061 NA|NA|NA GOKNOHPG_02177 405566.lhv_1009 9.3e-175 619.4 Lactobacillaceae prmA ko:K02687 ko00000,ko01000,ko03009 Bacteria 1TPKI@1239,3F47Z@33958,4HAMF@91061,COG2264@1,COG2264@2 NA|NA|NA J Ribosomal protein L11 methyltransferase GOKNOHPG_02178 1423748.BALB01000010_gene1097 8.2e-85 319.7 Lactobacillaceae ybaK ko:K03976 ko00000,ko01000,ko03016 Bacteria 1V6JF@1239,3F5H1@33958,4HHVB@91061,COG2606@1,COG2606@2 NA|NA|NA S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily GOKNOHPG_02179 1423754.BALY01000031_gene503 2e-36 160.2 Lactobacillaceae Bacteria 1UI8Y@1239,3F5RM@33958,4ISGF@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein GOKNOHPG_02180 1423748.BALB01000010_gene1091 2.5e-38 167.2 Lactobacillaceae ko:K14201 ko05150,map05150 ko00000,ko00001 Bacteria 1U7XQ@1239,2BNFG@1,32H3B@2,3FAAU@33958,4IHV3@91061 NA|NA|NA GOKNOHPG_02181 326425.lhe_0931 1.6e-93 348.6 Lactobacillaceae yxkA ko:K06910 ko00000 Bacteria 1VJEE@1239,3FBPI@33958,4IRQB@91061,COG1881@1,COG1881@2 NA|NA|NA S Phosphatidylethanolamine-binding protein GOKNOHPG_02182 405566.lhv_1004 6.7e-243 846.3 Lactobacillaceae yjjP Bacteria 1TNZH@1239,3F4FR@33958,4HU4D@91061,COG2966@1,COG2966@2,COG3610@1,COG3610@2 NA|NA|NA S Putative threonine/serine exporter GOKNOHPG_02183 405566.lhv_1003 2.4e-170 604.7 Lactobacillaceae citR Bacteria 1VSYQ@1239,3FCBZ@33958,4HU6A@91061,COG2390@1,COG2390@2 NA|NA|NA K Putative sugar-binding domain GOKNOHPG_02184 326425.lhe_0928 4.7e-16 89.4 Lactobacillaceae Bacteria 1U734@1239,29PV8@1,30ATG@2,3F8WW@33958,4IGXN@91061 NA|NA|NA GOKNOHPG_02185 405566.lhv_1001 4.1e-65 253.8 Lactobacillaceae Bacteria 1U6UG@1239,29PNX@1,30AM4@2,3F8I6@33958,4IGNA@91061 NA|NA|NA S Domain of unknown function DUF1828 GOKNOHPG_02186 326425.lhe_0926 3.6e-94 350.9 Lactobacillaceae ko:K16924,ko:K16927 M00582 ko00000,ko00002,ko02000 3.A.1.29,3.A.1.32 Bacteria 1V1GT@1239,3F5A7@33958,4HGAE@91061,COG4720@1,COG4720@2 NA|NA|NA S UPF0397 protein GOKNOHPG_02187 405566.lhv_0998 0.0 1118.6 Lactobacillaceae ykoD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 ko:K02006,ko:K16786,ko:K16787 ko02010,map02010 M00245,M00246,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPH8@1239,3F4XP@33958,4HAJM@91061,COG1122@1,COG1122@2 NA|NA|NA P ABC transporter, ATP-binding protein GOKNOHPG_02188 405566.lhv_0997 9.4e-139 499.6 Lactobacillaceae cbiQ ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 iSB619.SA_RS14165 Bacteria 1TPMV@1239,3F3Y9@33958,4HBTW@91061,COG0619@1,COG0619@2 NA|NA|NA P cobalt transport GOKNOHPG_02189 326425.lhe_0535 4.7e-134 483.8 Lactobacillaceae tagA 2.4.1.187 ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 GT26 Bacteria 1V3QV@1239,3F4WB@33958,4HH6B@91061,COG1922@1,COG1922@2 NA|NA|NA F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid GOKNOHPG_02190 326425.lhe_0536 8.5e-204 716.1 Lactobacillaceae csaB Bacteria 1UHSF@1239,3F428@33958,4HB04@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 GOKNOHPG_02191 326425.lhe_0537 1.8e-278 964.5 Lactobacillaceae pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 iYO844.BSU31750 Bacteria 1TPDW@1239,3F3K7@33958,4HAI4@91061,COG1488@1,COG1488@2 NA|NA|NA F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP GOKNOHPG_02192 405566.lhv_0541 8e-154 549.7 Lactobacillaceae nadE GO:0003674,GO:0003824,GO:0003952,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0033554,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_1910,iECW_1372.ECW_m1909,iEKO11_1354.EKO11_2035,iETEC_1333.ETEC_1772,iEcE24377_1341.EcE24377A_1961,iSFV_1184.SFV_1480,iSF_1195.SF1486,iSFxv_1172.SFxv_1676,iSSON_1240.SSON_1418,iS_1188.S1603,iWFL_1372.ECW_m1909 Bacteria 1TQ38@1239,3F43Z@33958,4HA2R@91061,COG0171@1,COG0171@2 NA|NA|NA F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source GOKNOHPG_02193 405566.lhv_0939 3.5e-214 750.7 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TT4J@1239,3FB6R@33958,4IRBE@91061,COG0675@1,COG0675@2 NA|NA|NA L Probable transposase GOKNOHPG_02194 326425.lhe_0390 1.4e-66 259.2 Lactobacillaceae Bacteria 1UFZH@1239,29V33@1,30GGE@2,3F5BQ@33958,4IF1H@91061 NA|NA|NA GOKNOHPG_02197 891391.LAC30SC_02640 2.7e-129 468.4 Lactobacillaceae pfoS ko:K07035 ko00000 Bacteria 1TS5F@1239,3FCB3@33958,4HC4N@91061,COG3641@1,COG3641@2 NA|NA|NA S Phosphotransferase system, EIIC GOKNOHPG_02198 1033837.WANG_1153 4.6e-256 890.2 Lactobacillaceae slpX Bacteria 1U50G@1239,2DKHC@1,309G6@2,3F3S2@33958,4IESF@91061 NA|NA|NA S SLAP domain GOKNOHPG_02199 405566.lhv_0532 1.7e-91 342.0 Lactobacillaceae Bacteria 1W6IZ@1239,28WK8@1,2ZIK8@2,3F68J@33958,4I01D@91061 NA|NA|NA GOKNOHPG_02202 326425.lhe_0532 8.6e-212 742.7 Lactobacillaceae Bacteria 1U569@1239,29NKT@1,309IS@2,3F4WR@33958,4IEXJ@91061 NA|NA|NA GOKNOHPG_02203 326425.lhe_0533 4.7e-123 447.2 Lactobacillaceae gntR1 ko:K03710,ko:K11922 ko00000,ko03000 Bacteria 1UYBW@1239,3FC8N@33958,4IPQD@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA GOKNOHPG_02204 326425.lhe_0534 1.8e-55 221.9 Lactobacillaceae tagD 2.7.7.15,2.7.7.39 ko:K00968,ko:K00980 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 M00090 R00856,R01890,R02590 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3KY@1239,3F65R@33958,4HGWZ@91061,COG0615@1,COG0615@2 NA|NA|NA IM Glycerol-3-phosphate cytidylyltransferase GOKNOHPG_02206 405566.lhv_1481 2e-138 500.0 Lactobacillaceae hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 1UI7V@1239,3F4JF@33958,4HA94@91061,COG4096@1,COG4096@2 NA|NA|NA L DEAD/DEAH box helicase GOKNOHPG_02207 405566.lhv_1481 6.9e-75 286.6 Lactobacillaceae hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 1UI7V@1239,3F4JF@33958,4HA94@91061,COG4096@1,COG4096@2 NA|NA|NA L DEAD/DEAH box helicase GOKNOHPG_02208 1033837.WANG_1559 4.7e-226 790.4 Lactobacillaceae Bacteria 1UYJN@1239,3FBEE@33958,4HF8I@91061,COG4640@1,COG4640@2 NA|NA|NA S response to antibiotic GOKNOHPG_02209 326425.lhe_0081 3.4e-32 143.7 Lactobacillaceae def 3.5.1.31,3.5.1.88 ko:K01450,ko:K01462 ko00270,ko00630,map00270,map00630 R00653 RC00165,RC00323 ko00000,ko00001,ko01000 Bacteria 1V73T@1239,3F6ZA@33958,4HISW@91061,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins GOKNOHPG_02210 326425.lhe_0078 1.7e-190 671.8 Lactobacillaceae pbpX1 Bacteria 1V4BS@1239,3F3QN@33958,4HJRT@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase GOKNOHPG_02211 326425.lhe_0077 0.0 1870.5 Lactobacillaceae Bacteria 1TQ62@1239,3F3YQ@33958,4HAJ1@91061,COG1061@1,COG1061@2,COG3886@1,COG3886@2 NA|NA|NA L Helicase C-terminal domain protein GOKNOHPG_02212 1423748.BALB01000018_gene1516 4.8e-68 263.8 Lactobacillaceae ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1TRUM@1239,3F3Y1@33958,4HE3V@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid GOKNOHPG_02213 1423748.BALB01000018_gene1516 1.3e-127 462.6 Lactobacillaceae ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1TRUM@1239,3F3Y1@33958,4HE3V@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid GOKNOHPG_02214 326425.lhe_1243 2.5e-158 564.7 Lactobacillaceae yitT Bacteria 1TRBT@1239,3F3PH@33958,4HBPR@91061,COG1284@1,COG1284@2 NA|NA|NA S Uncharacterised 5xTM membrane BCR, YitT family COG1284 GOKNOHPG_02215 1423748.BALB01000007_gene841 9.1e-105 386.3 Lactobacillaceae Bacteria 1U551@1239,29TNS@1,30EWM@2,3F4Q6@33958,4IEWA@91061 NA|NA|NA GOKNOHPG_02216 1423767.BALU01000006_gene713 2.4e-107 395.2 Lactobacillaceae thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545,iSB619.SA_RS06620 Bacteria 1TRWS@1239,3F44T@33958,4HCQN@91061,COG0083@1,COG0083@2 NA|NA|NA F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate GOKNOHPG_02217 1423748.BALB01000007_gene838 8e-24 115.9 Lactobacillaceae hom GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1294,iSB619.SA_RS06610 Bacteria 1TQ2H@1239,3F5BM@33958,4HBAP@91061,COG0460@1,COG0460@2 NA|NA|NA E homoserine dehydrogenase GOKNOHPG_02218 1423748.BALB01000007_gene838 2.5e-123 448.4 Lactobacillaceae hom GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1294,iSB619.SA_RS06610 Bacteria 1TQ2H@1239,3F5BM@33958,4HBAP@91061,COG0460@1,COG0460@2 NA|NA|NA E homoserine dehydrogenase GOKNOHPG_02219 891391.LAC30SC_06785 2.4e-241 841.3 Lactobacillaceae thrC 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS16355,iIT341.HP0098 Bacteria 1TPR0@1239,3F3UF@33958,4H9R7@91061,COG0498@1,COG0498@2 NA|NA|NA E Threonine synthase GOKNOHPG_02220 1229517.AMFD01000043_gene2144 6.7e-178 630.2 Lactococcus ko:K07498 ko00000 Bacteria 1V1XJ@1239,1YBYV@1357,4ID51@91061,COG5527@1,COG5527@2 NA|NA|NA L Lactococcus lactis RepB C-terminus GOKNOHPG_02221 1215915.BN193_11490 2.4e-43 182.2 Bacilli Bacteria 1V4IG@1239,2A9SW@1,30Z0H@2,4HHW5@91061 NA|NA|NA GOKNOHPG_02222 764298.STRMA_1275 7.5e-27 126.3 Bacilli 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1TT28@1239,4HK4M@91061,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain protein GOKNOHPG_02223 1133569.AHYZ01000024_gene414 1.8e-50 204.9 Lactobacillaceae ko:K19158 ko00000,ko01000,ko02048 Bacteria 1VAM5@1239,3F86X@33958,4HRX3@91061,COG4115@1,COG4115@2 NA|NA|NA S YoeB-like toxin of bacterial type II toxin-antitoxin system GOKNOHPG_02224 1400520.LFAB_17430 1.7e-38 164.9 Lactobacillaceae Bacteria 1U63Q@1239,2DKNJ@1,30A2H@2,3F6YR@33958,4IFT5@91061 NA|NA|NA S Antitoxin component of a toxin-antitoxin (TA) module GOKNOHPG_02225 60520.HR47_14815 1.3e-105 389.0 Lactobacillaceae ko:K04763 ko00000,ko03036 Bacteria 1V2RX@1239,3F4SP@33958,4IEJ7@91061,COG0582@1,COG0582@2 NA|NA|NA L Integrase GOKNOHPG_02226 1231377.C426_1433 1.6e-63 249.2 Lactococcus Bacteria 1V4YN@1239,1YCJR@1357,4I3YA@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins GOKNOHPG_02227 405566.lhv_1542 8.7e-79 299.7 Lactobacillaceae lacZ 3.2.1.23 ko:K12308 ko00052,map00052 R01105 RC00452 ko00000,ko00001,ko01000 Bacteria 1TQN6@1239,3F3PC@33958,4HARI@91061,COG1874@1,COG1874@2 NA|NA|NA G -beta-galactosidase GOKNOHPG_02228 405566.lhv_1542 3.3e-34 150.6 Lactobacillaceae lacZ 3.2.1.23 ko:K12308 ko00052,map00052 R01105 RC00452 ko00000,ko00001,ko01000 Bacteria 1TQN6@1239,3F3PC@33958,4HARI@91061,COG1874@1,COG1874@2 NA|NA|NA G -beta-galactosidase GOKNOHPG_02229 405566.lhv_1543 0.0 1185.2 Lactobacillaceae lacS ko:K03292,ko:K11104,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.1,2.A.2.2 Bacteria 1TRA5@1239,3F3P7@33958,4HCDS@91061,COG2190@1,COG2190@2,COG2211@1,COG2211@2 NA|NA|NA G Transporter GOKNOHPG_02230 272621.LBA1463 1.2e-141 509.6 Lactobacillaceae lacS ko:K03292,ko:K11104,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.1,2.A.2.2 Bacteria 1TRA5@1239,3F3P7@33958,4HCDS@91061,COG2190@1,COG2190@2,COG2211@1,COG2211@2 NA|NA|NA G Transporter GOKNOHPG_02231 1423748.BALB01000003_gene452 6.8e-48 196.4 Lactobacillaceae lacS ko:K03292,ko:K11104,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.1,2.A.2.2 Bacteria 1U7H6@1239,3F9P6@33958,4IHDQ@91061,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein GOKNOHPG_02232 326425.lhe_1439 2.1e-24 117.9 Lactobacillaceae lacS ko:K03292,ko:K11104,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.1,2.A.2.2 Bacteria 1TRA5@1239,3F3P7@33958,4HCDS@91061,COG2190@1,COG2190@2,COG2211@1,COG2211@2 NA|NA|NA G Transporter GOKNOHPG_02233 326425.lhe_1444 4.8e-190 670.2 Lactobacillaceae galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ7N@1239,3F3YF@33958,4H9U5@91061,COG1087@1,COG1087@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family GOKNOHPG_02234 326425.lhe_1443 3e-184 651.0 Lactobacillaceae lacM 3.2.1.23,3.2.1.35,3.2.1.51,3.2.1.97 ko:K01190,ko:K01197,ko:K01206,ko:K17624 ko00052,ko00511,ko00531,ko00600,ko01100,map00052,map00511,map00531,map00600,map01100 M00076,M00077 R01105,R01678,R03355,R04783,R06114,R07824,R07825,R10905 RC00049,RC00452 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042,ko04147 GH101,GH29 Bacteria 1TRVA@1239,3F51Z@33958,4HFMH@91061,COG3250@1,COG3250@2 NA|NA|NA G beta-galactosidase GOKNOHPG_02235 326425.lhe_1442 0.0 1317.8 Lactobacillaceae lacL 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 Bacteria 1TPDC@1239,3F4EI@33958,4HANW@91061,COG3250@1,COG3250@2 NA|NA|NA G Belongs to the glycosyl hydrolase 2 family GOKNOHPG_02236 405566.lhv_1547 1.2e-183 649.0 Lactobacillaceae lacR ko:K02529 ko00000,ko03000 Bacteria 1TPZJ@1239,3F3PB@33958,4HC9Z@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator GOKNOHPG_02237 326425.lhe_1844 1.4e-267 928.3 Lactobacillaceae ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 ko:K06885 ko00000 Bacteria 1TPVB@1239,3FC99@33958,4IQRC@91061,COG1078@1,COG1078@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. GOKNOHPG_02238 326425.lhe_1845 5.5e-43 179.9 Lactobacillaceae Bacteria 1U6GK@1239,29PEC@1,30ACI@2,3F7VQ@33958,4IG8S@91061 NA|NA|NA GOKNOHPG_02239 1423748.BALB01000008_gene964 2.5e-148 531.6 Lactobacillaceae Bacteria 1TRQ7@1239,3F3ZI@33958,4HE30@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family GOKNOHPG_02240 326425.lhe_1847 3.9e-176 624.0 Lactobacillaceae prs 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2848 Bacteria 1TQ6Q@1239,3F3U2@33958,4HB61@91061,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) GOKNOHPG_02241 1423748.BALB01000008_gene962 8.5e-183 646.4 Lactobacillaceae Bacteria 1U56A@1239,2DKI3@1,309IT@2,3F4WY@33958,4IEXK@91061 NA|NA|NA S SLAP domain GOKNOHPG_02242 1033837.WANG_1620 1.8e-114 419.5 Lactobacillaceae Bacteria 1U59E@1239,29DXA@1,300V7@2,3F59A@33958,4IF0P@91061 NA|NA|NA S SLAP domain GOKNOHPG_02244 585524.HMPREF0493_1297 5.1e-34 149.8 Lactobacillaceae repA Bacteria 1VHQA@1239,2DP1C@1,3304N@2,3F55E@33958,4HPY6@91061 NA|NA|NA S Replication initiator protein A GOKNOHPG_02246 272621.LBA1597 2.9e-58 231.9 Lactobacillaceae Bacteria 1U6U1@1239,29PNJ@1,30AKS@2,3F8HJ@33958,4IGMV@91061 NA|NA|NA GOKNOHPG_02247 1423748.BALB01000014_gene1310 5.6e-12 77.4 Lactobacillaceae Bacteria 1U890@1239,2BRVA@1,32KVH@2,3FAQ1@33958,4II6V@91061 NA|NA|NA GOKNOHPG_02248 326425.lhe_0075 3.3e-160 570.9 Lactobacillaceae xth GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPFB@1239,3F4GK@33958,4HAIU@91061,COG0708@1,COG0708@2 NA|NA|NA L exodeoxyribonuclease III GOKNOHPG_02249 326425.lhe_0074 9.2e-79 299.3 Lactobacillaceae yniA GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 Bacteria 1U79A@1239,3F3RK@33958,4HAZS@91061,COG3001@1,COG3001@2 NA|NA|NA G Phosphotransferase enzyme family GOKNOHPG_02250 326425.lhe_0074 1.7e-66 258.5 Lactobacillaceae yniA GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 Bacteria 1U79A@1239,3F3RK@33958,4HAZS@91061,COG3001@1,COG3001@2 NA|NA|NA G Phosphotransferase enzyme family GOKNOHPG_02251 1033837.WANG_1627 3.4e-191 674.1 Lactobacillaceae ldhA 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3FB6C@33958,4HH0S@91061,COG1052@1,COG1052@2 NA|NA|NA C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family GOKNOHPG_02252 525365.HMPREF0548_1471 3.1e-25 120.9 Lactobacillaceae Bacteria 1U821@1239,2BPU5@1,32IMK@2,3FAFK@33958,4IHZE@91061 NA|NA|NA GOKNOHPG_02253 748727.CLJU_c05760 2e-24 118.6 Clostridiaceae 3.6.1.1 ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1V8EF@1239,24JN0@186801,36JWH@31979,COG0221@1,COG0221@2 NA|NA|NA C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions GOKNOHPG_02254 1033837.WANG_1623 8.4e-148 529.6 Lactobacillaceae 3.1.3.102,3.1.3.104,3.1.3.23 ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R00804,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1U5C1@1239,3F5HG@33958,4IF34@91061,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase GOKNOHPG_02255 1423748.BALB01000018_gene1523 9.7e-106 389.4 Lactobacillaceae tetP ko:K02355 ko00000,ko03012,ko03029 Bacteria 1TPQH@1239,3F4B4@33958,4HAS9@91061,COG0480@1,COG0480@2 NA|NA|NA J elongation factor G GOKNOHPG_02256 1423748.BALB01000018_gene1523 4.2e-213 747.3 Lactobacillaceae tetP ko:K02355 ko00000,ko03012,ko03029 Bacteria 1TPQH@1239,3F4B4@33958,4HAS9@91061,COG0480@1,COG0480@2 NA|NA|NA J elongation factor G GOKNOHPG_02258 1423748.BALB01000018_gene1524 4.2e-158 563.9 Lactobacillaceae yvgN Bacteria 1TPM1@1239,3F3PW@33958,4HARE@91061,COG0656@1,COG0656@2 NA|NA|NA C Aldo keto reductase GOKNOHPG_02259 1033837.WANG_0329 1.6e-199 701.8 Lactobacillaceae Bacteria 1TRSF@1239,3FB5V@33958,4HAYI@91061,COG2826@1,COG2826@2 NA|NA|NA L COG2826 Transposase and inactivated derivatives, IS30 family GOKNOHPG_02261 326425.lhe_1553 8.9e-30 136.0 Lactobacillaceae Bacteria 1VMY1@1239,3F814@33958,4HRA4@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins GOKNOHPG_02263 1033837.WANG_1111 5.9e-283 979.5 Lactobacillaceae Bacteria 1TSRV@1239,3F46B@33958,4HCIZ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC-type multidrug transport system, ATPase and permease components GOKNOHPG_02264 1033837.WANG_1110 6.8e-287 992.6 Lactobacillaceae Bacteria 1TSRV@1239,3F46B@33958,4HCIZ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC-type multidrug transport system, ATPase and permease components GOKNOHPG_02266 1033837.WANG_1108 1.3e-58 232.3 Lactobacillaceae Bacteria 1V7E2@1239,3F5II@33958,4HJ1U@91061,COG0515@1,COG0515@2 NA|NA|NA KLT Protein kinase domain GOKNOHPG_02267 405566.lhv_1092 5.5e-158 563.5 Lactobacillaceae Bacteria 1UZVA@1239,3F4KP@33958,4HH09@91061,COG3039@1,COG3039@2 NA|NA|NA L An automated process has identified a potential problem with this gene model GOKNOHPG_02268 525365.HMPREF0548_1861 8.5e-11 72.8 Lactobacillaceae Bacteria 1U580@1239,29NJD@1,309JD@2,3F53B@33958,4IEZA@91061 NA|NA|NA S Bacteriocin helveticin-J GOKNOHPG_02269 326425.lhe_0065 8.1e-131 473.0 Lactobacillaceae yjjG GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006206,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008655,GO:0009058,GO:0009112,GO:0009410,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019856,GO:0019859,GO:0030145,GO:0034641,GO:0034654,GO:0042221,GO:0042578,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.102,3.1.3.104,3.1.3.5,3.8.1.2 ko:K01560,ko:K07025,ko:K08723,ko:K20862 ko00230,ko00240,ko00361,ko00625,ko00740,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00740,map00760,map01100,map01110,map01120 M00125 R00183,R00511,R00548,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287,R07280 RC00017,RC00697 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_4614 Bacteria 1TS3W@1239,3F4NI@33958,4HADE@91061,COG1011@1,COG1011@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase GOKNOHPG_02270 326425.lhe_0064 7.2e-178 629.8 Lactobacillaceae ABC-SBP ko:K01989,ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPB0@1239,3F462@33958,4HESK@91061,COG2984@1,COG2984@2 NA|NA|NA S ABC transporter GOKNOHPG_02271 1033837.WANG_1617 1.4e-124 452.6 Lactobacillaceae XK27_08840 ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPDJ@1239,3F40J@33958,4HBMY@91061,COG4120@1,COG4120@2 NA|NA|NA U Belongs to the binding-protein-dependent transport system permease family GOKNOHPG_02272 326425.lhe_0062 1.4e-136 492.3 Lactobacillaceae XK27_08845 ko:K05833 M00247 ko00000,ko00002,ko02000 Bacteria 1TPAN@1239,3F3NW@33958,4HCHC@91061,COG1101@1,COG1101@2 NA|NA|NA S ABC transporter, ATP-binding protein GOKNOHPG_02273 326425.lhe_0061 2.2e-39 167.9 Lactobacillaceae Bacteria 1U644@1239,2BZTJ@1,30A2T@2,3F6ZQ@33958,4IFTP@91061 NA|NA|NA GOKNOHPG_02274 525365.HMPREF0548_1309 1.3e-11 75.1 Lactobacillaceae Bacteria 1U6MU@1239,2AR30@1,31GC3@2,3F85Z@33958,4IGEM@91061 NA|NA|NA GOKNOHPG_02275 326425.lhe_0059 5.8e-103 380.2 Lactobacillaceae 3.1.1.5 ko:K10804 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Bacteria 1VAT2@1239,3F5TI@33958,4HKYJ@91061,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase GOKNOHPG_02276 405566.lhv_0043 3e-174 617.8 Lactobacillaceae Bacteria 1TSBK@1239,3F46E@33958,4HBYJ@91061,COG0628@1,COG0628@2 NA|NA|NA K AI-2E family transporter GOKNOHPG_02277 405566.lhv_0042 0.0 1513.0 Lactobacillaceae rtpR 1.1.98.6,1.17.4.1,1.17.4.2 ko:K00525,ko:K00527,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02014,R02017,R02018,R02019,R02020,R02022,R02023,R02024,R04315,R11633,R11634,R11635,R11636 RC00013,RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1TT3U@1239,3F3VU@33958,4HFF1@91061,COG0209@1,COG0209@2 NA|NA|NA F ribonucleoside-triphosphate reductase activity GOKNOHPG_02278 326425.lhe_0056 1.1e-07 61.6 Lactobacillaceae Bacteria 1VF26@1239,2DNM7@1,32Y2X@2,3F6AM@33958,4HP82@91061 NA|NA|NA S Domain of unknown function (DUF4430) GOKNOHPG_02279 326425.lhe_0055 4.2e-84 317.4 Lactobacillaceae ko:K16924,ko:K16927 M00582 ko00000,ko00002,ko02000 3.A.1.29,3.A.1.32 Bacteria 1V5GD@1239,3F5H7@33958,4HI8Y@91061,COG4720@1,COG4720@2 NA|NA|NA S ECF transporter, substrate-specific component GOKNOHPG_02280 326425.lhe_0054 6e-97 360.1 Lactobacillaceae yvqK GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 ko:K00798,ko:K13821 ko00250,ko00330,ko00860,ko01100,ko01110,ko01130,map00250,map00330,map00860,map01100,map01110,map01130 M00122 R00245,R00707,R00708,R01253,R01492,R04444,R04445,R05051,R05220,R07268 RC00080,RC00083,RC00216,RC00242,RC00255,RC00533 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 1UZ2W@1239,3F6MY@33958,4HF48@91061,COG2096@1,COG2096@2 NA|NA|NA S cob(I)alamin adenosyltransferase GOKNOHPG_02281 405566.lhv_0038 1.6e-148 531.9 Lactobacillaceae Bacteria 1V2HX@1239,3F3MV@33958,4HK25@91061,COG4905@1,COG4905@2 NA|NA|NA S Putative ABC-transporter type IV GOKNOHPG_02282 326425.lhe_0051 3.1e-227 794.3 Lactobacillaceae Bacteria 1U62D@1239,29P37@1,30A1D@2,3F6V7@33958,4IFRD@91061 NA|NA|NA S LPXTG cell wall anchor motif GOKNOHPG_02283 525365.HMPREF0548_1318 8.6e-185 652.9 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase GOKNOHPG_02284 525365.HMPREF0548_1318 3.6e-47 194.1 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase GOKNOHPG_02285 891391.LAC30SC_10935 2.3e-48 198.4 Lactobacillaceae vsr ko:K07458 ko00000,ko01000,ko03400 Bacteria 1V3S8@1239,3F771@33958,4HJ0T@91061,COG3727@1,COG3727@2 NA|NA|NA L DNA mismatch endonuclease Vsr GOKNOHPG_02286 353496.LBU_1698 2.2e-146 525.4 Lactobacillaceae 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Bacteria 1TSNX@1239,3FCF7@33958,4HF9J@91061,COG0270@1,COG0270@2 NA|NA|NA H C-5 cytosine-specific DNA methylase GOKNOHPG_02287 353496.LBU_1700 1.9e-211 742.3 Lactobacillaceae Z012_07420 3.1.21.5 ko:K01156 ko00000,ko01000,ko02048 Bacteria 1UIN3@1239,3F50P@33958,4ITC7@91061,COG0610@1,COG0610@2 NA|NA|NA V Z1 domain GOKNOHPG_02288 353496.LBU_1699 2.4e-106 392.5 Lactobacillaceae Bacteria 1U6C6@1239,2CXRX@1,32T2G@2,3F7K7@33958,4IG3U@91061 NA|NA|NA L NgoFVII restriction endonuclease GOKNOHPG_02289 326425.lhe_0048 6.8e-60 236.5 Lactobacillaceae Bacteria 1V6JC@1239,3F58C@33958,4IF0F@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family GOKNOHPG_02290 326425.lhe_0046 1.1e-57 229.2 Lactobacillaceae Bacteria 1V192@1239,3F5GG@33958,4IJ3S@91061,COG0846@1,COG0846@2 NA|NA|NA K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form GOKNOHPG_02291 326425.lhe_0045 4.3e-130 470.7 Lactobacillaceae ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 ko:K02069 M00211 ko00000,ko00002,ko02000 9.B.25.1 Bacteria 1UY1N@1239,3F4P1@33958,4HDM4@91061,COG0390@1,COG0390@2 NA|NA|NA S Uncharacterised protein family (UPF0014) GOKNOHPG_02292 326425.lhe_0044 5.4e-110 403.7 Lactobacillaceae ybbL GO:0005575,GO:0005623,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0016020,GO:0019725,GO:0030003,GO:0042592,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071944,GO:0098771 ko:K02065,ko:K02068 ko02010,map02010 M00210,M00211,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1V3DQ@1239,3F4UY@33958,4HHGU@91061,COG4619@1,COG4619@2 NA|NA|NA S ABC transporter, ATP-binding protein GOKNOHPG_02293 326425.lhe_0043 1.9e-29 134.4 Lactobacillaceae WQ51_00220 ko:K07729 ko00000,ko03000 Bacteria 1VERT@1239,3F85E@33958,4HNID@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins GOKNOHPG_02295 891391.LAC30SC_05200 2.9e-109 401.4 Lactobacillaceae 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1V86D@1239,3F7IT@33958,4HJKH@91061,COG0286@1,COG0286@2 NA|NA|NA V site-specific DNA-methyltransferase (adenine-specific) activity GOKNOHPG_02296 985255.APHJ01000048_gene409 2.7e-14 86.7 Bacteroidetes Bacteria 2DV5Q@1,33U6N@2,4P2AX@976 NA|NA|NA GOKNOHPG_02297 353496.LBU_0995 1.1e-57 229.9 Lactobacillaceae Bacteria 1U2DR@1239,3F4F5@33958,4HBX2@91061,COG1061@1,COG1061@2 NA|NA|NA L Type III restriction enzyme, res subunit GOKNOHPG_02298 891391.LAC30SC_05190 2.7e-37 161.4 Lactobacillaceae Bacteria 1U2DR@1239,3F4F5@33958,4HBX2@91061,COG1061@1,COG1061@2 NA|NA|NA L Type III restriction enzyme, res subunit GOKNOHPG_02299 891391.LAC30SC_05190 8.4e-58 229.6 Lactobacillaceae Bacteria 1U2DR@1239,3F4F5@33958,4HBX2@91061,COG1061@1,COG1061@2 NA|NA|NA L Type III restriction enzyme, res subunit GOKNOHPG_02300 891391.LAC30SC_05190 0.0 1118.2 Lactobacillaceae Bacteria 1U2DR@1239,3F4F5@33958,4HBX2@91061,COG1061@1,COG1061@2 NA|NA|NA L Type III restriction enzyme, res subunit GOKNOHPG_02301 272621.LBA0475 5.9e-112 410.6 Lactobacillaceae Bacteria 1U2DR@1239,3F4F5@33958,4HBX2@91061,COG1061@1,COG1061@2 NA|NA|NA L Type III restriction enzyme, res subunit GOKNOHPG_02302 257314.LJ_1686 1.6e-70 272.3 Lactobacillaceae Bacteria 1V414@1239,2C5T7@1,2ZU21@2,3F6JK@33958,4HHIP@91061 NA|NA|NA GOKNOHPG_02303 326425.lhe_0037 4.6e-178 630.6 Lactobacillaceae ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 1U59Y@1239,3F5BK@33958,4IF1G@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family GOKNOHPG_02304 326425.lhe_0037 3.1e-11 73.9 Lactobacillaceae ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 1U59Y@1239,3F5BK@33958,4IF1G@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family GOKNOHPG_02305 1033837.WANG_1443 3.7e-27 126.7 Lactobacillaceae Bacteria 1U6VC@1239,29PP2@1,30AMM@2,3F8JJ@33958,4IGP8@91061 NA|NA|NA GOKNOHPG_02306 1033837.WANG_1444 6.9e-36 156.0 Lactobacillaceae Bacteria 1U6XE@1239,29PQQ@1,30ANX@2,3F8NV@33958,4IGRP@91061 NA|NA|NA GOKNOHPG_02307 1033837.WANG_1444 3.3e-19 100.1 Lactobacillaceae Bacteria 1U6XE@1239,29PQQ@1,30ANX@2,3F8NV@33958,4IGRP@91061 NA|NA|NA GOKNOHPG_02308 326425.lhe_0034 1.5e-152 545.4 Lactobacillaceae Bacteria 1V478@1239,294J7@1,2ZRYS@2,3F60V@33958,4IJ1U@91061 NA|NA|NA S Replication initiation factor GOKNOHPG_02309 326425.lhe_0033 3.6e-120 437.6 Lactobacillaceae Bacteria 1TPHE@1239,3F688@33958,4I32F@91061,COG1674@1,COG1674@2 NA|NA|NA D Ftsk spoiiie family protein GOKNOHPG_02310 326425.lhe_0030 3.5e-55 221.1 Lactobacillaceae Bacteria 1U7N4@1239,29Q7V@1,30B6W@2,3F9XR@33958,4IHJE@91061 NA|NA|NA K Helix-turn-helix XRE-family like proteins GOKNOHPG_02312 326425.lhe_0028 1.9e-119 435.3 Lactobacillaceae yhiD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07507 ko00000,ko02000 9.B.20 Bacteria 1V409@1239,3F3QE@33958,4HK8H@91061,COG1285@1,COG1285@2 NA|NA|NA S MgtC family GOKNOHPG_02313 326425.lhe_0027 3.7e-240 837.0 Lactobacillaceae Bacteria 1UHVZ@1239,3F3SU@33958,4ISGG@91061,COG2267@1,COG2267@2 NA|NA|NA I Protein of unknown function (DUF2974) GOKNOHPG_02314 405566.lhv_0024 6.8e-35 152.9 Lactobacillaceae Bacteria 1U7X6@1239,2BNBG@1,32GZ3@2,3FAA7@33958,4IHUJ@91061 NA|NA|NA GOKNOHPG_02316 525365.HMPREF0548_1192 4.6e-41 174.1 Lactobacillaceae yyaQ Bacteria 1V4K7@1239,3F73S@33958,4IFV9@91061,COG2315@1,COG2315@2 NA|NA|NA S YjbR GOKNOHPG_02317 525365.HMPREF0548_1202 6.9e-22 109.4 Lactobacillaceae proW ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1UHWH@1239,3F5XQ@33958,4HJIP@91061,COG1174@1,COG1174@2 NA|NA|NA P ABC transporter, permease protein GOKNOHPG_02318 525365.HMPREF0548_1206 2.3e-17 94.4 Lactobacillaceae Bacteria 1VQW3@1239,3F64W@33958,4HV4F@91061,COG2364@1,COG2364@2 NA|NA|NA S Membrane GOKNOHPG_02319 1423790.BN53_01340 1.3e-61 243.0 Lactobacillaceae Bacteria 1V3S1@1239,3F6JQ@33958,4HHI0@91061,COG2267@1,COG2267@2 NA|NA|NA I Alpha/beta hydrolase family GOKNOHPG_02320 1133569.AHYZ01000050_gene233 9.8e-33 146.7 Bacilli ko:K03523 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 Bacteria 1VAY6@1239,4HHJM@91061,COG1268@1,COG1268@2 NA|NA|NA S Biotin synthase GOKNOHPG_02321 525365.HMPREF0548_1256 1.1e-28 132.1 Lactobacillaceae ko:K18843 ko00000,ko02048 Bacteria 1VAII@1239,3F8YB@33958,4HM80@91061,COG1598@1,COG1598@2 NA|NA|NA S HicB family GOKNOHPG_02323 1423748.BALB01000020_gene1637 8.6e-44 182.6 Lactobacillaceae Bacteria 1U71I@1239,2BVUC@1,30AS9@2,3F8UZ@33958,4IGW0@91061 NA|NA|NA GOKNOHPG_02324 405566.lhv_0512 2e-61 241.5 Lactobacillaceae Bacteria 1UZVH@1239,2BVJW@1,32QXP@2,3F6CN@33958,4HFK6@91061 NA|NA|NA S Uncharacterised protein family (UPF0236) GOKNOHPG_02325 1033837.WANG_1761 1.2e-85 322.8 Lactobacillaceae pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 R01570,R01876,R02296,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 iHN637.CLJU_RS08925 Bacteria 1TPCH@1239,3F45P@33958,4H9NP@91061,COG0213@1,COG0213@2 NA|NA|NA F pyrimidine-nucleoside phosphorylase GOKNOHPG_02326 862514.HMPREF0623_1597 1.3e-26 125.9 Lactobacillaceae ytgB Bacteria 1VENK@1239,3F7EK@33958,4HNKV@91061,COG2261@1,COG2261@2 NA|NA|NA S Transglycosylase associated protein GOKNOHPG_02327 326425.lhe_0278 7.2e-34 149.4 Lactobacillaceae GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 ko:K14060 ko00000 Bacteria 1V51N@1239,3F51V@33958,4HDX2@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain GOKNOHPG_02328 543734.LCABL_21290 7.2e-116 423.3 Lactobacillaceae Bacteria 1TQ93@1239,3F4RD@33958,4HDNZ@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein GOKNOHPG_02329 1423732.BALS01000131_gene404 7e-148 530.0 Lactobacillaceae glcU ko:K05340 ko00000,ko02000 2.A.7.5 Bacteria 1TQBN@1239,3F4K2@33958,4HAVH@91061,COG4975@1,COG4975@2 NA|NA|NA U sugar transport GOKNOHPG_02330 1229758.C270_00275 3.2e-29 135.2 Leuconostocaceae ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 1V15F@1239,4AX5X@81850,4HFCE@91061,COG3266@1,COG3266@2,COG4932@1,COG4932@2 NA|NA|NA M the current gene model (or a revised gene model) may contain a GOKNOHPG_02331 1229758.C270_00275 7.4e-29 133.7 Leuconostocaceae ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 1V15F@1239,4AX5X@81850,4HFCE@91061,COG3266@1,COG3266@2,COG4932@1,COG4932@2 NA|NA|NA M the current gene model (or a revised gene model) may contain a GOKNOHPG_02333 405566.lhv_0511 6.4e-137 493.4 Lactobacillaceae Bacteria 1UZVA@1239,3F4KP@33958,4HH09@91061,COG3039@1,COG3039@2 NA|NA|NA L An automated process has identified a potential problem with this gene model GOKNOHPG_02335 405566.lhv_1770 0.0 1483.0 Lactobacillaceae helD 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP39@1239,3F486@33958,4H9Y5@91061,COG3973@1,COG3973@2 NA|NA|NA L DNA helicase GOKNOHPG_02336 326425.lhe_0448 8.4e-125 453.0 Lactobacillaceae XK27_08875 Bacteria 1VW9X@1239,3F60X@33958,4HWF8@91061,COG5549@1,COG5549@2 NA|NA|NA O PFAM peptidase M10A and M12B, matrixin and adamalysin GOKNOHPG_02337 405566.lhv_1772 1.1e-126 459.1 Lactobacillaceae pgm3 Bacteria 1TQWQ@1239,3F524@33958,4HF2N@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family GOKNOHPG_02339 326425.lhe_0012 1.1e-175 623.2 Lactobacillaceae ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1UV7Z@1239,3F5Y3@33958,4I2UY@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region GOKNOHPG_02340 585524.HMPREF0493_0173 6.5e-51 207.6 Bacilli Bacteria 1VSDT@1239,4HUN9@91061,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase GOKNOHPG_02341 326425.lhe_0015 3.1e-84 317.8 Lactobacillaceae Bacteria 1TSH3@1239,3F7MT@33958,4HGIJ@91061,COG0515@1,COG0515@2 NA|NA|NA KLT Protein kinase domain GOKNOHPG_02342 326425.lhe_0372 0.0 1203.3 Lactobacillaceae fruA 2.7.1.202,2.7.1.204 ko:K02768,ko:K02769,ko:K02770,ko:K02806,ko:K20112 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273,M00807 R03232,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.5 Bacteria 1TPKU@1239,3F44C@33958,4H9KR@91061,COG1299@1,COG1299@2,COG1445@1,COG1445@2,COG1762@1,COG1762@2 NA|NA|NA GT Phosphotransferase System GOKNOHPG_02343 1423748.BALB01000012_gene1207 1.3e-165 589.0 Lactobacillaceae pfkB 2.7.1.11,2.7.1.56 ko:K00882,ko:K16370 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00345 R00756,R02071,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ36@1239,3F3SG@33958,4HANU@91061,COG1105@1,COG1105@2 NA|NA|NA H Belongs to the carbohydrate kinase PfkB family. LacC subfamily GOKNOHPG_02344 1423748.BALB01000012_gene1208 2e-141 508.4 Lactobacillaceae fruR ko:K03436 ko00000,ko03000 Bacteria 1TSF8@1239,3F3JB@33958,4HDT9@91061,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain GOKNOHPG_02345 1033837.WANG_0775 2.1e-72 278.1 Lactobacillaceae Bacteria 1U5KS@1239,2F916@1,309SE@2,3F65Y@33958,4IFBR@91061 NA|NA|NA S Iron-sulphur cluster biosynthesis GOKNOHPG_02347 405566.lhv_0934 6.6e-125 453.4 Lactobacillaceae 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 1TST7@1239,3F54T@33958,4HEFP@91061,COG1051@1,COG1051@2,COG4111@1,COG4111@2 NA|NA|NA F NUDIX domain GOKNOHPG_02348 326425.lhe_0887 8.3e-268 929.1 Lactobacillaceae pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 Bacteria 1TPDW@1239,3F3K7@33958,4HAI4@91061,COG1488@1,COG1488@2 NA|NA|NA F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP GOKNOHPG_02349 326425.lhe_0886 1.1e-106 392.5 Lactobacillaceae pncA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 ko:K16788 ko00000,ko02000 2.A.88.5 iSB619.SA_RS09955 Bacteria 1V1CY@1239,3F41F@33958,4HFRS@91061,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family GOKNOHPG_02350 405566.lhv_1327 8.9e-170 602.8 Lactobacillaceae cysK GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP30@1239,3F4VD@33958,4HAMU@91061,COG0031@1,COG0031@2 NA|NA|NA E Belongs to the cysteine synthase cystathionine beta- synthase family GOKNOHPG_02351 326425.lhe_1257 3.9e-150 537.3 Lactobacillaceae metAA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0008899,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS11970 Bacteria 1TQVR@1239,3F5CA@33958,4H9W4@91061,COG1897@1,COG1897@2 NA|NA|NA E Transfers an acetyl group from acetyl-CoA to GOKNOHPG_02352 405566.lhv_1325 7.8e-86 323.2 Lactobacillaceae cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPKY@1239,3F3SF@33958,4H9TI@91061,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol GOKNOHPG_02353 1423748.BALB01000013_gene1297 8e-129 466.5 Lactobacillaceae cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPKY@1239,3F3SF@33958,4H9TI@91061,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol GOKNOHPG_02354 405566.lhv_0152 0.0 2017.3 Lactobacillaceae Bacteria 1TR8N@1239,3FC1B@33958,4HEJM@91061,COG1501@1,COG1501@2 NA|NA|NA G Belongs to the glycosyl hydrolase 31 family GOKNOHPG_02355 326425.lhe_0669 1.7e-49 201.8 Lactobacillaceae pacL 3.6.3.8,3.6.3.9 ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 ko00000,ko00001,ko01000,ko04147 3.A.3.1,3.A.3.2 Bacteria 1TPF5@1239,3FC0Z@33958,4HTQ4@91061,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus GOKNOHPG_02356 1423748.BALB01000004_gene626 1e-63 249.2 Lactobacillaceae srlB 2.7.1.198 ko:K02781 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 Bacteria 1VGKB@1239,3F8EZ@33958,4HNJN@91061,COG3731@1,COG3731@2 NA|NA|NA G PTS system glucitol/sorbitol-specific IIA component GOKNOHPG_02357 326425.lhe_0671 1.7e-210 738.4 Lactobacillaceae yubA Bacteria 1TQ84@1239,3F418@33958,4H9SR@91061,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter GOKNOHPG_02358 326425.lhe_0672 7.9e-105 386.3 Lactobacillaceae trmL GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 ko:K03216 ko00000,ko01000,ko03016 Bacteria 1V3GW@1239,3F42Y@33958,4HFNY@91061,COG0219@1,COG0219@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily GOKNOHPG_02359 326425.lhe_0673 1.4e-68 265.4 Lactobacillaceae WQ51_03320 Bacteria 1VHA6@1239,3FCDF@33958,4HPTC@91061,COG4835@1,COG4835@2 NA|NA|NA S Protein of unknown function (DUF1149) GOKNOHPG_02360 405566.lhv_0707 0.0 1387.5 Lactobacillaceae ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K03466 ko00000,ko03036 3.A.12 Bacteria 1TPJR@1239,3F3JZ@33958,4H9WA@91061,COG1674@1,COG1674@2 NA|NA|NA D Belongs to the FtsK SpoIIIE SftA family GOKNOHPG_02361 405566.lhv_0708 6.2e-224 783.1 Lactobacillaceae 2.7.1.26,2.7.7.2 ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPN6@1239,3F3SA@33958,4H9P5@91061,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 inactive domain protein GOKNOHPG_02362 326425.lhe_0676 8.2e-235 819.3 Lactobacillaceae Bacteria 1TP5I@1239,3F4MU@33958,4H9YG@91061,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 GOKNOHPG_02363 326425.lhe_0677 3.1e-133 481.1 Lactobacillaceae Bacteria 1V0YW@1239,3FBEA@33958,4ISGK@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase GOKNOHPG_02364 326425.lhe_0678 4.4e-139 501.1 Lactobacillaceae ymfM ko:K15539 ko00000 Bacteria 1V1N7@1239,3F3SM@33958,4HKW3@91061,COG1426@1,COG1426@2 NA|NA|NA S Helix-turn-helix domain GOKNOHPG_02365 405566.lhv_0712 2.7e-97 361.3 Lactobacillaceae pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 iSB619.SA_RS06365 Bacteria 1V6PJ@1239,3F4BI@33958,4HCEX@91061,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family GOKNOHPG_02366 326425.lhe_0680 4.7e-194 683.7 Lactobacillaceae recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 ko:K03553 ko03440,map03440 M00729 ko00000,ko00001,ko00002,ko03400 Bacteria 1TPD5@1239,3F3KU@33958,4HAG5@91061,COG0468@1,COG0468@2 NA|NA|NA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage GOKNOHPG_02367 326425.lhe_0681 4e-218 764.2 Lactobacillaceae rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TP48@1239,3F3WX@33958,4HC9J@91061,COG1418@1,COG1418@2 NA|NA|NA S Endoribonuclease that initiates mRNA decay GOKNOHPG_02368 405566.lhv_0715 4.2e-209 733.8 Lactobacillaceae tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 ko:K02851 R08856 RC00002 ko00000,ko01000,ko01003,ko01005 Bacteria 1TP9V@1239,3F4JV@33958,4H9KT@91061,COG0472@1,COG0472@2 NA|NA|NA M transferase GOKNOHPG_02369 326425.lhe_0683 1.2e-115 422.5 Lactobacillaceae yvyE 3.4.13.9 ko:K01271 ko00000,ko01000,ko01002 Bacteria 1V6MQ@1239,3F3SQ@33958,4HBIT@91061,COG1739@1,COG1739@2 NA|NA|NA S YigZ family GOKNOHPG_02370 326425.lhe_0684 6.2e-246 856.3 Lactobacillaceae comFA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K02240 M00429 ko00000,ko00002,ko02044 3.A.11.1 Bacteria 1TPZE@1239,3F3TQ@33958,4HB00@91061,COG4098@1,COG4098@2 NA|NA|NA L Helicase C-terminal domain protein GOKNOHPG_02371 405566.lhv_0718 7.7e-134 483.0 Lactobacillaceae comFC ko:K02242 M00429 ko00000,ko00002,ko02044 Bacteria 1V73S@1239,3F714@33958,4HJ6R@91061,COG1040@1,COG1040@2 NA|NA|NA S Competence protein GOKNOHPG_02372 326425.lhe_0686 4e-93 347.4 Lactobacillaceae hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 ko:K05808 ko00000,ko03009 Bacteria 1V1D5@1239,3F40M@33958,4HFX9@91061,COG1544@1,COG1544@2 NA|NA|NA J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase GOKNOHPG_02373 326425.lhe_0687 0.0 1531.5 Lactobacillaceae secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1TPEY@1239,3F4DH@33958,4HA22@91061,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane GOKNOHPG_02374 326425.lhe_0688 8.6e-187 659.4 Lactobacillaceae prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 1TPSB@1239,3F3SN@33958,4H9N2@91061,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA GOKNOHPG_02375 405566.lhv_0722 4.4e-24 117.1 Lactobacillaceae Bacteria 1U6A5@1239,29P93@1,30A77@2,3F7F0@33958,4IG1D@91061 NA|NA|NA GOKNOHPG_02376 326425.lhe_0690 4.9e-179 633.6 Lactobacillaceae hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06023 ko00000,ko01000 Bacteria 1TP5Z@1239,3F3Z3@33958,4HAXR@91061,COG1493@1,COG1493@2 NA|NA|NA F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion GOKNOHPG_02377 1423748.BALB01000001_gene178 7.8e-157 559.7 Lactobacillaceae lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 ko:K03438,ko:K13292 ko00000,ko01000,ko03009 Bacteria 1TPAK@1239,3F42N@33958,4HAT0@91061,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins GOKNOHPG_02378 326425.lhe_0692 1.1e-186 659.1 Lactobacillaceae gpsA GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 Bacteria 1TQ5P@1239,3F4C8@33958,4HAXW@91061,COG0240@1,COG0240@2 NA|NA|NA I Glycerol-3-phosphate dehydrogenase GOKNOHPG_02379 1033837.WANG_0969 6e-147 526.9 Lactobacillaceae glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,3.2.1.141,3.2.1.20 ko:K00700,ko:K01187,ko:K01236,ko:K17734 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 M00565 R00028,R00801,R00802,R02110,R06087,R06088,R09995,R11256 RC00028,RC00049,RC00077 ko00000,ko00001,ko00002,ko01000,ko01002,ko04147 CBM48,GH13,GH31 iAPECO1_1312.APECO1_3025,iECNA114_1301.ECNA114_3542,iECOK1_1307.ECOK1_3857,iECS88_1305.ECS88_3830,iECSF_1327.ECSF_3253,iJN678.glgB,iLF82_1304.LF82_0837,iNRG857_1313.NRG857_17030,iUTI89_1310.UTI89_C3941 Bacteria 1TP4M@1239,3F4KT@33958,4HAPM@91061,COG0296@1,COG0296@2 NA|NA|NA G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position GOKNOHPG_02380 1033837.WANG_0968 9.5e-14 81.6 Lactobacillaceae glgC 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TNZW@1239,3F4IA@33958,4HAZX@91061,COG0448@1,COG0448@2 NA|NA|NA H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans GOKNOHPG_02381 1033837.WANG_0968 1.2e-96 359.4 Lactobacillaceae glgC 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TNZW@1239,3F4IA@33958,4HAZX@91061,COG0448@1,COG0448@2 NA|NA|NA H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans GOKNOHPG_02382 405566.lhv_0210 2.5e-118 431.4 Lactobacillaceae guaB2 Bacteria 1TQNJ@1239,3F67A@33958,4HPRA@91061,COG2452@1,COG2452@2 NA|NA|NA L Resolvase, N terminal domain GOKNOHPG_02383 405566.lhv_0211 4e-300 1036.6 Lactobacillaceae Bacteria 1U7T5@1239,3F51F@33958,4HNFV@91061,COG0675@1,COG0675@2 NA|NA|NA L Putative transposase DNA-binding domain GOKNOHPG_02384 405566.lhv_0728 0.0 1152.5 Lactobacillaceae pgm GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2,5.4.2.8 ko:K01835,ko:K01840 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114,M00549 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP2N@1239,3F457@33958,4HADU@91061,COG1109@1,COG1109@2 NA|NA|NA G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain GOKNOHPG_02385 326425.lhe_0695 0.0 1314.7 Lactobacillaceae uvrB ko:K03702,ko:K08999 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TPKB@1239,3F3XM@33958,4HB81@91061,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage GOKNOHPG_02386 326425.lhe_0696 0.0 1886.7 Lactobacillaceae uvrA ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TPIJ@1239,3F4TZ@33958,4HAW9@91061,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate GOKNOHPG_02387 1423748.BALB01000001_gene171 1.2e-81 309.3 Lactobacillaceae Bacteria 1V759@1239,3F58J@33958,4HK5F@91061,COG3247@1,COG3247@2 NA|NA|NA S Short repeat of unknown function (DUF308) GOKNOHPG_02388 405566.lhv_0732 1.4e-164 585.5 Lactobacillaceae rapZ GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K06958 ko00000,ko03019 Bacteria 1TPS4@1239,3F4NY@33958,4H9KM@91061,COG1660@1,COG1660@2 NA|NA|NA S Displays ATPase and GTPase activities GOKNOHPG_02389 405566.lhv_0733 7.6e-194 682.9 Lactobacillaceae ybhK Bacteria 1TPNV@1239,3F4D5@33958,4HA0Z@91061,COG0391@1,COG0391@2 NA|NA|NA S Required for morphogenesis under gluconeogenic growth conditions GOKNOHPG_02390 405566.lhv_0734 3.4e-169 600.9 Lactobacillaceae whiA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944 ko:K09762 ko00000 Bacteria 1TP2X@1239,3F4AB@33958,4HB4H@91061,COG1481@1,COG1481@2 NA|NA|NA K May be required for sporulation GOKNOHPG_02391 1423748.BALB01000001_gene167 6.7e-99 366.7 Lactobacillaceae clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 1TQ91@1239,3F3M0@33958,4HA8J@91061,COG0740@1,COG0740@2 NA|NA|NA O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins GOKNOHPG_02392 326425.lhe_0702 0.0 1076.2 Lactobacillaceae Bacteria 1W1FZ@1239,2FIUN@1,34AK2@2,3F4QV@33958,4HYXZ@91061 NA|NA|NA S SH3-like domain GOKNOHPG_02393 326425.lhe_0703 2.8e-111 407.9 Lactobacillaceae Bacteria 1UYU8@1239,3F3YK@33958,4HE0K@91061,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase GOKNOHPG_02394 1423748.BALB01000001_gene164 2.6e-269 934.1 Lactobacillaceae ycaM ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1TRFS@1239,3FCAH@33958,4HBIP@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid GOKNOHPG_02395 1423748.BALB01000001_gene163 1.9e-251 874.8 Lactobacillaceae Bacteria 1W1FZ@1239,2FIUN@1,34AK2@2,3F4QI@33958,4HYXZ@91061 NA|NA|NA # 2213 queries scanned # Total time (seconds): 4.61881685257 # Rate: 479.13 q/s