LOCUS       c00074_JAFIWI0..       12818 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAFIWI010000110.1 Lactobacillus helveticus strain 314
            NODE_61_length_12818_cov_36.923632, whole genome shotgun sequence.
ACCESSION   JAFIWI010000110
VERSION     JAFIWI010000110
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2022-06-21 17:43:14
            Original ID  :: JAFIWI010000110.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12818
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12818
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4110:12818]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4111..12818
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..12818
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12818
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             256..663
                     /locus_tag="ctg74_1"
                     /transl_table=11
                     /translation="MRKQIISAAGIMLAVIGLGAATTQSVDATVTNPVRQGKRLNLTRN
                     ATVYNRHGVKVGHLRKGKLYKVRAIKVVNRIKKHSFVYDENGEKIPGKFLKRGAKVNYL
                     GHKEINEKPFIKIADGEYVKALNALTTVTNH"
     CDS             complement(731..3004)
                     /locus_tag="ctg74_2"
                     /transl_table=11
                     /translation="MSEKLHGLTQAEADKRLKEDGLNEVPEPEYNFFKEFLSKLWNLSA
                     WILEGALILECILGKWIQSLFVLLMLLFAAFNGASKKKQSRRVLNTISHKLTPKVAVER
                     DGKWIKIDSKQLVRGDLISLQRGDVLAADVKMVSGKIACDESSITGESKPVKKNIDDTA
                     YAGTTVVEGDGLAIVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFDTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKESVLTA
                     DLTSIQDAANLNLLLLDKTGTITENKTAVASWSDSSDLPDKDVLALAGSATDKRNAGII
                     DIAIDEYLKENNIPVMDVEHFTPFTSDTGYSMAEVDGHNVKLGSFKQLSLIDKNANEAV
                     EGINFKAGRSVAVLIDDKLAGVFILQDKVRKDSKAALAELKKRGVRPIMLTGDNQRTAA
                     AVAEQVDLTGNVISIHDFDESTDIDELAGIADVLPEDKLKMVKFFQEKGYIVGMTGDGV
                     NDSPTLKQAEVGIAVSNAADVAKRSSKMVLLDDGLSSIVKILDAGHRVYQRMTTWSLAK
                     LARTAELTMLLTFGYLFFNYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     RLAKIAFSLAAGWTVIGIAFVSYLNMHGWSHNSISTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGIVQIADVALTFILALCGLAMAQISWQNLLITVVVALIAAIIIDLIYQPA
                     MKNR"
     CDS             3133..3987
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     73.6; E-value: 3.1e-23)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg74_3"
                     /sec_met_domain="LysR_substrate (E-value: 2e-30, bitscore:
                     95.9, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 9.1e-24, bitscore: 73.6,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIKQLRYFLVVAEEKQITSAAKRLYIAQPPLSYQLKQLEIELGA
                     QLFKRTAHGIELTDAGQILQSYASEILSLSESVKNQVHKTVSGELGTIAIGMASSSTGL
                     IPMKSFQDLTKFYPEINFDIYEDNTFGIIDKLEKKTIDLGIVRTPYNRNGLNAKTLTTE
                     RMMAVTVDPKFKDKTELRIKDLNEQPLIIYRRFEEIFNQTFAHHGIKPFYAVKCDDSRT
                     AITWAKRKMGIALVPESIASTYAPDDLIPIKHSNWITHLQLVWRKDQKVTPLMKRIIDS
                     LSR"
     CDS             4111..4245
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_4"
                     /sec_met_domain="Amidinotransf (E-value: 4.8e-12, bitscore:
                     35.8, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLHRPGRELENLSPDILNRMLIDDIPYLKIAQKEHDYFAHTLEK"
     CDS             4377..4787
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_5"
                     /sec_met_domain="Amidinotransf (E-value: 1.8e-27, bitscore:
                     86.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYLIAMPVNEMVKQIIAGIRKNEIQNATPSLADLAEDPDYPFYL
                     DPMPNVYFTRDQQAAIGNGMTINRMTFRARRRESLFMETVLKNHPDFKNANIPIWRDRY
                     THGRLEGGDELILNNHVFSNRYFSKNFRCRNH"
     CDS             4735..5373
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_6"
                     /sec_met_domain="Amidinotransf (E-value: 9.6e-51, bitscore:
                     163.0, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFLAIGISQRTSAAAITDLAHNLFGHSSYDTILAIKIPHNHAMMH
                     LDTVFTMINYDQCTVHPFILDKSGKIDIYVLEQDDHGEIKITPETDLIKVLKNYLHLSE
                     IDLIPTGGGDAIAAPREQWNDGSNTLAIAPGEVVTYDRNYVSNDLLRKHGILVHEIHSS
                     ELSRGRGGPRCMSVHLFVKIYKRRQNEIFTKCVSRQKFIKMQRLYSSGA"
     CDS             5536..5859
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_7"
                     /sec_met_domain="OTCace_N (E-value: 1.9e-26, bitscore:
                     83.1, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAGEIHLGKKESIEDTAKVLGSMFDGIEYRGFAQKDVEDLAKYS
                     GVPVWNGLTDKWHPTQMLADFMTIKEKFGHLKVLTLAYVGDGRDNVADSLLVAGSILEL
                     MYT"
     CDS             5940..6335
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_8"
                     /sec_met_domain="OTCace (E-value: 1.8e-34, bitscore: 109.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LITDDIEQGVKGANIIYTDVWVSMCENDWSERIKLLKPYTVTMKM
                     MYMTGTPDDQLIFMHCLPAFHDRTTKVGKEIYEKYGLGEVEVTDEVFNSQYAWQFTEAE
                     NRLHSIKAIMTATLGNLFIPSVDEGSK"
     CDS             6338..6760
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_9"
                     /sec_met_domain="AA_kinase (E-value: 1.7e-13, bitscore:
                     40.9, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIVVALGGNAIEAGDNSAAAQEKQIKKTMKVVAKMIENGDQVA
                     IVHGNGPQVGNLLLQQYKGSSKDNPAMPLDTVVAMTQGSIGYWMQRALDDQFKHTNYPH
                     QAVALITQIIVKANDPTFKNLTKPIGLFYTFNEMQR"
     CDS             6929..7270
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_10"
                     /sec_met_domain="AA_kinase (E-value: 3.8e-19, bitscore:
                     59.4, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKDDSLQGVAGVIDKDFSAAKLAEDIQADELVILTTVDNAYVNYN
                     QPDQAPIGKIKIDQLKKYLEAGQFVAGSMKPKIEAVIDFVEKTGKTAIITSLRNASKLD
                     DGVGTIVYN"
     CDS             7287..7823
                     /locus_tag="ctg74_11"
                     /transl_table=11
                     /translation="MNIFQEGNPQNIAQVLAGKDYRVALQQAIFKKYPDATLVDINLNI
                     PGPIKNNRYLIKLFDYGIKQLEEIWQNKGYDYKLVKALNNDAGCENFYVLRESSKVVKL
                     STILFEENNKIGRLFDADVLIKGKTALSRQELEYSSRRCYLCNRPAKECARSRRHSVEE
                     MQRYISSLYAKYVNN"
     CDS             7943..9109
                     /locus_tag="ctg74_12"
                     /transl_table=11
                     /translation="MKLKKNQDNLKQIASLIEYAFLKDSDLTTDSNFMTRYDHSDGYGY
                     FDQEKLTSYMMVNKFKAEIFGYHVPLAGIGYVASYPEYRGRGHISKLMKEILFELHDQK
                     IPVANLAPFSEKFYRNYGFSNSIYQKEYRFLGAALASFRLPRKGKIIRGKWNDLIVQNG
                     VIQLYERQLHTDDERNTIIREAWWWNRLDDYYHHREIAVYFDEAGRPMSYLIYRIIDNC
                     FMADELYSITPQGLLSILGFMAAHIGSIKEFCMILPEKSLLAELFPEQNELDIQLHPYM
                     MSRIIDFQKVLSCMRPLQEGAFNIEVNYDDQCPWNIGVWQLTNYDHQVKCERKEDELVD
                     FSGPITTWTQILLGRLTMESAIKLGLITDYRIKKLDFVKGKVSFYDYF"
     CDS             9125..9286
                     /locus_tag="ctg74_13"
                     /transl_table=11
                     /translation="MSKQKKVRLLKFLSVVVSGINVVISLLIMFNKYQIRKDKKQIADE
                     GHAPLDEN"
     CDS             9289..9894
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg74_14"
                     /sec_met_domain="LysR_substrate (E-value: 7e-19, bitscore:
                     58.2, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRIAYFNQLGRRQLDRIVDQFKQKHSDVEIELIGMGHDEAFD
                     KLAKNEVDLAISDLRDDQLDFKKEILGQEAVMAILQKGSYPSGVQMINKDDLADLTCFI
                     VAKPEEEAAELHLFKDIYQIRSPFIASNSVEEAALLVASGSGYFLMNEATASLISNDTL
                     QRLFLLSNGQQMWQKIAAFYTNEDAVIKDFILLAKKVY"
     CDS             10170..10400
                     /locus_tag="ctg74_15"
                     /transl_table=11
                     /translation="MSGQTTKMKNNLFYEINPWISFENWSLYRVMPQKINGKKHNVLLY
                     SSRYDGGNYYRSKKLAKQMKNYKFKKVDYHL"
     CDS             10566..10730
                     /locus_tag="ctg74_16"
                     /transl_table=11
                     /translation="MKLENAPVLNLFRLEINPEKHEIYTQKVEKYMLNAKNALFMQSGH
                     EDQRNIKTT"
     CDS             10727..11206
                     /locus_tag="ctg74_17"
                     /transl_table=11
                     /translation="LIESYQNDDAYQKHESLSQVQQFERDLKDIVNSQVKVKLYPEFIS
                     TKPEKLAITHDNQYVVYLTEIGVQLGKGDEFANAVMKEMKTAVEKEDGILAMLAGTIMN
                     QPNEWFSLEVYKTEETYYEEHLKTRHLKKYLEATKYVVESKGLHLLKPDCIMDQG"
     CDS             complement(11757..12818)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_18"
                     /sec_met_domain="AA_kinase (E-value: 4.4e-32, bitscore:
                     101.8, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="SKKTKKGRIHHGIKIPCFLRQLINKIFKRYELIAQYFNLHEKELS
                     EIKRLLLTLPKLDYYRMATFKAHGERLNAMLITKILNHQGIKTRFLEPKDVGLIVTRTP
                     NNAEVNPETYVNLKRIKLNKDERIIFPGFYGITPPAHISTFSRGGSDITGAILARGFNA
                     NLYENFTDVDAIFSSNPHIIDHPKPIKKMTYQEMRELSYAGFSVFHDEALIPAIQGEIP
                     VNVKNTNAPEKPGTLIVPEEGFTAKKTITGIAGGKNFAALYLRKYMLNKGAGFTLKLME
                     IFNRHHVSYEHMPSSIDDLSVIFKKDVLNDVICNEIQTSLNPDQMQWINDYAITMVGGE
                     GMKDKLTLCASIL"
ORIGIN
        1 ttccctcctt tctttttaag attatatcaa acatatgttt aagaaagaag gggggaacaa
       61 gcaaaaaaac taaaaaaagc cggattcatc acgggattaa aatcccgtgt tttctccggc
      121 aattaatcaa taaataattt tagcagaatt aagcaaatag ttataaaaca gatgagtaaa
      181 aaatgcttcc aattcgataa tttttgataa aataagggat ggagaatggt ataaacacta
      241 cgggggtgga ttatgatgag aaaacaaatt atttctgctg caggtataat gttagcagtt
      301 attggattag gcgcagcaac tacacaaagc gttgatgcaa ctgttactaa tccagttaga
      361 caaggtaaga gattaaatct aactagaaat gctactgttt ataatagaca tggtgttaaa
      421 gttggacatt taagaaaggg aaagctttac aaagtacgtg ccataaaagt agttaataga
      481 atcaaaaagc attcctttgt ttatgatgag aatggtgaaa aaatcccagg caaattttta
      541 aagcgtggtg ctaaggttaa ctatttaggt cataaagaaa ttaatgaaaa accatttatc
      601 aaaattgctg atggtgaata tgttaaggct ttgaatgcct tgactacagt tactaatcat
      661 taatcaaaaa aacactctga aaactacatt gtagtaatgt agttttcaga gtgtttttgt
      721 tttaagttaa ttatctgttt ttcattgctg gttgataaat caaatctata ataattgctg
      781 caattaatgc aaccacaacg gtaattaata agttttgcca actaatttga gccattgcta
      841 aaccgcataa agctaaaata aaggttaatg cgacatcggc aatttgaaca atacctacaa
      901 gtttagatgg gtaatcttgc cagaagtatt tacgagttct agtaattaat acaattaaca
      961 ttgcacttag aactaagtaa acatagacca tggtagagat agaattgtga ctccagccat
     1021 gcatgttgag gtagctgaca aaagcgatac cgataactgt ccaacctgca gcaagagaga
     1081 atgcgatttt ggctaacctt gccatattcc aattttctgg tttgtaagta atatgggtac
     1141 ggtcggtacc aatcatcatg gtaaccatgt tattcatgat tgtgtaaata accatagcat
     1201 ttaatgccat tggaatatag ttgaagaaga gatagccgaa ggttaaaagc atagttaatt
     1261 cggcggttct ggcgagctta gcaagtgacc aagtagtcat tcgttgatat acacggtgac
     1321 cagcatcaag aattttaaca atagagctta agccatcatc tagaagcacc atcttacttg
     1381 aacgcttggc aacatcggca gcgttagaaa cagcaatacc aacttcagct tgctttaaag
     1441 taggagagtc gttaacacca tcaccagtca taccaacgat ataacctttt tcttggaaga
     1501 atttaaccat cttaagttta tcttcaggta aaacatcggc aatccctgct aattcatcaa
     1561 tatcggtgct ttcatcaaag tcatgaatag agataacgtt accagttaaa tcaacttgtt
     1621 cagcgactgc tgcggcagtt ctttgattat ccccagttaa catgattgga cgtacgcccc
     1681 gttttttaag ttctgctaaa gcagccttag agtcctttct tactttatct tgtaagataa
     1741 atactcccgc aagtttgtca tcaattaaca cggcaactga gcgtccagct ttaaaattga
     1801 tgccttcaac tgcttcattt gcattcttat cgattaatga aagttgctta aatgaaccta
     1861 acttaacatt gtgaccatct acttcagcca tagaatagcc agtgtcagaa gtaaatgggg
     1921 taaagtgttc aacgtccatg acagggatat tgttttcttt taagtattca tcaatggcga
     1981 tatcaatgat acctgcattg cgcttatcag ttgcactacc ggctaaagca agtacatctt
     2041 tatctggcaa atcgcttgaa tcgctccaac tagcaactgc agttttgttt tcagtgattg
     2101 ttcccgtctt atcaagtaaa agcaagttta agttagctgc atcttggata ctagttaaat
     2161 cagctgttaa gacgctttct ttacttaaac gggttgcttc aaatgaattg gacaatgcaa
     2221 aggttgacgg catcgcaacc ggaattgaag cgatgaacat catggctaag aatggcaaca
     2281 tgttgataaa cgtatcaaaa ttaccaccct taaagaatga agcaatgata ataactaagg
     2341 taagtacacc gtccagtagg caaaggtagt aaataatctt agttaaaagt tgttgcaagt
     2401 gaccaggtgc ggctgaattg ttgatcaagt taatggtctt accacttctt gaatctttac
     2461 cagttgcagt aacaattgct aatccatcgc cttcaacaac agtagtacca gcataagctg
     2521 tgtcatcaat gttcttttta acgggcttgg attcaccggt aattgagctt tcatcacagg
     2581 cgatcttacc gctaaccatt tttacatcgg ctgcaagtac atctccacgt tgaagtgaga
     2641 ttaagtcgcc tctaactaat tgcttagagt caattttgat ccacttacca tcgcgttcta
     2701 cagccacctt aggggttagc ttatgtgaaa tggtatttaa tacccgccgt gactgtttct
     2761 tcttggatgc accgttaaaa gccgcaaaaa gaagcatcaa caagacgaac aaagattgaa
     2821 tccatttgcc taagatacat tcgaggatta aggcaccttc tagaatccag gcagaaagat
     2881 tccataattt tgatagaaat tccttaaaaa agttgtattc gggttcaggt acttcgttta
     2941 acccatcttc tttaagtctc ttatctgctt cggcttgagt taagccatgc aatttttcag
     3001 acattttatt ccctccaaat ctaccttaat aaagtagcac atatgttgtt tgaatgaaaa
     3061 tactaaatta aaatataaga tatagaaatt tttaataaga gatacaacta aaataaaaag
     3121 gatagattat taatgaatat taaacaatta cgctactttt tagtagtagc cgaagaaaag
     3181 caaatcactt cagcagctaa aagactatac attgcacaac cgccgctgag ttatcaatta
     3241 aagcaactag aaatagaact aggagcacaa ttatttaagc gtactgctca tggaattgaa
     3301 ttaacagatg ctggacaaat tttgcagagc tatgctagtg aaattctctc tttatcagaa
     3361 agcgtgaaaa atcaggttca taaaactgtt tcaggtgaac taggcacgat tgcaataggc
     3421 atggcttcat catcaactgg actaattcct atgaaaagtt ttcaagattt aactaagttt
     3481 tatccggaaa tcaactttga tatttatgaa gataatacct ttggcattat cgataaattg
     3541 gaaaagaaga caatcgattt aggaattgtg cgtacgcctt ataatcgtaa tggcttaaat
     3601 gcaaaaactt taactactga aagaatgatg gcagttactg ttgatcccaa atttaaggat
     3661 aagacggaat taaggattaa agatctaaat gagcagcccc tcattattta tcgaagattt
     3721 gaagaaattt ttaaccagac ttttgctcat catgggatta agccgtttta tgctgttaaa
     3781 tgtgatgatt ctagaacagc gattacttgg gcgaagagaa aaatggggat tgctcttgtt
     3841 cctgaatcta ttgcttctac gtatgcacct gatgatctta ttcctattaa acatagtaat
     3901 tggattacgc atttgcaatt agtgtggcgc aaggatcaaa aggtgacgcc tttaatgaaa
     3961 agaataatag attcactaag ccgttaagat tgtaacttct acctaatcga tccataatca
     4021 ttgtaagcgg atacataatt tgaattagga ggcgctataa tgactgactt aattcatgtt
     4081 tattccgaaa ttggcaaatt ataaacagtt atgctgcatc gaccgggaag agaattagaa
     4141 aatctttcac cggatatctt aaatcgaatg ttaattgacg atattccata tttaaaaata
     4201 gctcaaaaag agcatgacta ttttgcccac actttggaaa aatagggagt tcatgtcgtt
     4261 tatttagaag atttattagc tcactctttg actaatcaag atgtccgtac aaaatttgta
     4321 gatcaattat tagaagaatc caatataaaa aagaagatcc attacatcaa ttactgatgg
     4381 actatttaat agcaatgcca gtaaatgaaa tggttaagca aataattgct ggtattagaa
     4441 aaaatgaaat acaaaatgca actccttcat tagccgatct agctgaagat ccagattatc
     4501 cattttattt ggatccaatg ccaaatgtgt attttactcg tgatcaacaa gcagctattg
     4561 gtaatggcat gactattaat agaatgacgt ttagagctag aagacgtgaa tcattattta
     4621 tggaaaccgt tttaaagaat catcccgact ttaaaaatgc caatattcct atttggcgtg
     4681 atcgttacac tcatggacgt ttagaaggtg gcgatgagct gattttaaac aatcatgttt
     4741 ttagcaatcg gtatttctca aagaacttcc gctgccgcaa tcactgacct tgctcataac
     4801 ctgtttggtc attctagtta tgacacaatt ttagcaatta aaataccaca taatcatgcc
     4861 atgatgcatc tggatacagt ctttacaatg attaattatg atcagtgtac cgttcatcct
     4921 tttattttag acaaatcagg aaagattgat atttatgttt tagagcaaga tgatcatggt
     4981 gagattaaaa ttaccccaga aactgatttg atcaaagtgt taaagaatta tttgcactta
     5041 tcggagattg acctaattcc aaccggaggt ggggatgcaa ttgcagcccc aagagagcag
     5101 tggaatgatg gctcgaatac tttggctatt gcgccaggtg aagtcgttac atatgatcgt
     5161 aattatgtat caaatgattt gttaagaaag catggcattt tagttcatga aattcattca
     5221 agtgagcttt ctcgtggccg tggaggtcca agatgtatgt ctgtccactt gttcgtgaag
     5281 atttataaga ggcgtcaaaa tgaaatattt acaaaatgtg tttcaaggca gaagtttatt
     5341 aaaatgcaaa gactatactc cagcggagct taactatcta attgatttcg cacttcattt
     5401 gaaggaacta aagaaaatat ttcgcatgaa tatttaaaag gaaagaatat agctctttta
     5461 tttaaaaaat cttcaacaag aacacgttca gcctttgtag ttgcatgcaa tgatttaggc
     5521 gcaaatcctg aatatatggg tgctggtgaa attcatttag gtaaaaagga aagtattgaa
     5581 gatactgcaa aggttttggg cagtatgttt gatggtattg aatatcgcgg ttttgctcaa
     5641 aaagatgtag aagatttggc taaatattct ggtgtccctg tttggaatgg tttaacagat
     5701 aaatggcatc cgacccaaat gttggctgac tttatgacta ttaaagaaaa gtttggacat
     5761 ttaaaggtac ttactttagc ttatgtaggc gatggacgtg ataatgttgc cgacagtctt
     5821 ttagtggctg gcagcatctt ggagttaatg tacacatagt tacgccaaag cctttattca
     5881 ctcaccctga tgtacaaaaa attgcagaag gttttgccaa agattctgga tcaagaaatt
     5941 tgattactga tgacattgaa caaggcgtta aaggtgcaaa tattatttat actgatgtct
     6001 gggtatcaat gtgtgaaaat gactggagtg agagaatcaa attgttaaag ccttacacgg
     6061 ttacaatgaa gatgatgtat atgacaggca ccccggatga tcaactaatc tttatgcact
     6121 gtttgcctgc gtttcatgat cgcactacta aagttggcaa agaaatttat gaaaaatatg
     6181 gtctaggtga agtggaagtt acagatgaag tctttaactc tcaatacgct tggcaattta
     6241 ctgaagcgga aaatagattg cattctatca aagcaataat gaccgctact ttgggcaatt
     6301 tgtttattcc gtcagttgat gaaggaagta aataaagatg aaaagaatag ttgtagcttt
     6361 gggtggcaat gctattgaag caggtgataa tagtgcagct gcccaagaaa agcagattaa
     6421 aaagacaatg aaggttgttg ctaaaatgat tgaaaatggt gatcaggtag cgattgttca
     6481 tggtaatggc ccacaggttg gtaatttgct tttgcaacaa tacaaaggtt caagtaaaga
     6541 taatcccgct atgccgcttg atacagtagt agcaatgact caaggcagta tcggctattg
     6601 gatgcaaagg gccttagacg atcagtttaa acatacaaat tatccacatc aagctgttgc
     6661 tttaattact cagataatag ttaaggcgaa tgatccaact tttaaaaatc taactaaacc
     6721 aattggccta ttttatacat ttaacgaaat gcagaggtaa aaaatctatc atcctgaata
     6781 tacttataag caagatgcag gtcgaggcta tcgtcaagta gtttcttctc caaagcccgt
     6841 taaaattatt aatgcaccag tcattgacac tttactaaag agcaagtttg ttcctattgc
     6901 ggccggaggt ggtggaattc ctgttgtagt gaaagacgat agtttgcaag gcgtagcagg
     6961 agtaattgat aaagacttca gtgccgcaaa actagctgaa gatattcaag cagatgaatt
     7021 agttattcta actactgttg acaatgccta cgtgaactat aatcaacctg atcaagctcc
     7081 tattggaaaa ataaagattg atcaattaaa gaagtatcta gaagctggcc aatttgtcgc
     7141 aggcagcatg aagccaaaaa ttgaagctgt cattgatttc gtagagaaaa caggaaagac
     7201 tgcaattatt acctctttaa gaaatgcaag taaacttgat gatggagtag gtacaattgt
     7261 ttataattaa ctgcggtgag atataaatga acatttttca agaaggaaat ccgcaaaata
     7321 ttgctcaggt attagctgga aaagattatc gtgtagcttt gcagcaagct atttttaaaa
     7381 agtatcctga tgcgactttg gttgatataa acttaaatat cccggggcca attaaaaata
     7441 atcgatattt aatcaaatta tttgattacg gaattaaaca attagaagaa atatggcaga
     7501 ataagggata tgactataaa ttagtaaaag cattaaataa tgatgctgga tgtgaaaatt
     7561 tctatgtttt gcgagaatct agcaaagtag ttaaattatc tacaatttta tttgaagaaa
     7621 ataataaaat aggacgatta tttgatgccg atgtattaat taaagggaaa actgcacttt
     7681 cacgccaaga gcttgaatac tctagtcgcc gctgctattt atgcaatcgc cctgctaaag
     7741 agtgtgctcg atcacggcga cactcagtag aagagatgca aagatacatt tctagtttat
     7801 atgcgaagta tgtaaataat taaaacggga tgggaggcta atcatcccgt tttttcattt
     7861 aaatcttaaa aaagctaacg aaaaatacat aaaatgttct aaaatataag taaagttatg
     7921 aatatatatt gtaaggaaaa ctatgaaatt aaagaaaaac caagacaatt taaaacaaat
     7981 tgcttcattg attgaatatg cttttttaaa agattctgat ttgactacag atagtaactt
     8041 tatgacccga tatgatcata gtgatggata tggatatttt gatcaagaaa aattgaccag
     8101 ttatatgatg gtcaataagt ttaaagctga gatatttggt tatcatgttc cactggcagg
     8161 tattggttat gtggcatcat atcctgaata cagaggacgt ggacatatat ctaaattaat
     8221 gaaagaaatt ctttttgagt tgcatgatca aaaaatccca gttgcaaatc tagctccatt
     8281 ttcagaaaaa ttttatcgta attatggttt tagcaatagt atttatcaaa aagaatatcg
     8341 ctttttgggg gctgcacttg cttctttcag attaccacgc aaaggtaaga taattcgtgg
     8401 aaaatggaat gatttgattg ttcaaaatgg tgtgattcaa ttatatgaac gtcagttgca
     8461 tactgacgat gaaagaaata cgatcatcag agaagcttgg tggtggaata gattagatga
     8521 ttattatcat catcgagaga ttgctgttta cttcgatgaa gctggtcggc cgatgagcta
     8581 cttgatttat cgcataattg ataactgttt tatggctgat gaattatatt caattacgcc
     8641 tcaaggatta ttaagcatat taggctttat ggcagctcat atagggtcaa ttaaagagtt
     8701 ttgtatgata ttgcctgaga agtctttatt ggctgaactt tttccagagc aaaatgaatt
     8761 ggatattcaa cttcatccat atatgatgag tagaattatt gatttccaaa aagtcttgtc
     8821 atgcatgcgc ccattgcaag agggtgcttt taacatcgaa gttaattatg atgatcagtg
     8881 tccatggaat attggcgttt ggcaattaac taattatgat caccaagtta agtgtgaacg
     8941 aaaagaagat gaactagttg atttctctgg tccaattaca acatggactc aaatcttatt
     9001 aggacgttta actatggaat ccgcaattaa acttggtttg atcacagatt atcgaattaa
     9061 aaagttggac tttgtaaaag gtaaagtctc attttatgat tatttttaga agaaggtatc
     9121 caaaatgagt aagcaaaaga aagttagatt actaaaattt ttaagcgtgg tagttagtgg
     9181 aataaatgtg gttatttcgc tattgattat gttcaacaaa tatcaaatta gaaaagataa
     9241 aaaacaaata gcagatgaag gtcatgcccc attggatgaa aattaactat gaaaaaattg
     9301 agaatagcat actttaacca acttggtaga agacaattag atcgaattgt agaccaattt
     9361 aagcaaaaac attctgatgt agaaattgaa ttaattggaa tgggacacga tgaagctttt
     9421 gataaattag ccaaaaatga agttgattta gcgattagtg atttgcgcga tgatcagctc
     9481 gattttaaga aagaaatctt aggtcaggaa gcagtaatgg ctattttgca aaagggtagt
     9541 tatcctagcg gtgttcagat gatcaataaa gatgatctag ctgatttaac ctgttttatt
     9601 gtagctaagc ctgaagaaga ggctgcagaa ctccatttat ttaaagatat ttatcagatt
     9661 agaagcccat tcattgcttc aaattccgta gaagaggcag cattgttagt agcttctgga
     9721 tcaggatatt ttttaatgaa tgaagcaacc gccagtttaa ttagtaatga tactttacaa
     9781 cgattgtttt tattgtctaa tggacaacaa atgtggcaaa agattgcagc tttttatacc
     9841 aatgaagatg cagtaattaa agattttatt ttgttagcta aaaaagtata ttaatctatc
     9901 ttggaacagc aaaatactgt aaaattaata atgaaagcga atccataatt ttacaactgg
     9961 agatgatttt atgctagaga gaaaattatt gcctttgtca gccatggtac tcatatgata
    10021 gtaatgcaca tagcggtaga aaaattactt ttactgcgca tacggttaat ggaaaaatca
    10081 tttacactca agaccaatca attattagcg attactttaa tggcaatatt caagatcagg
    10141 ctggttttga tcgagctacc aaaaattgga tgtcaggtca aacaactaag atgaaaaata
    10201 atctatttta tgagattaat ccatggatta gttttgaaaa ttggagtcta tatagagtaa
    10261 tgcctcaaaa gattaatggt aaaaagcata atgttttatt gtattcaagt agatacgatg
    10321 gcggcaatta ctatagaagt aagaaattgg ctaaacaaat gaaaaattat aagtttaaaa
    10381 aggtagacta tcatttgtaa aatttaatat agaagaaaag cttcaatcaa tctttaaaga
    10441 attgattgaa tttttttgtt aaaaaacttc aaattataga aattatgtta agttgatttt
    10501 ggcagtaact tttttgaaaa aatagtttat aatatcaata aaaattaatt tggtaggaat
    10561 aaaaaatgaa attagagaat gcacctgttt taaatttatt tagattagaa ataaatcctg
    10621 aaaagcatga aatatatact caaaaagtgg aaaagtatat gttaaatgca aagaatgcat
    10681 tatttatgca gagcggtcat gaagatcaaa ggaatataaa aactacttga tagaaagtta
    10741 tcaaaatgac gatgcttatc aaaaacatga gtctttaagt caagtccagc aatttgaacg
    10801 tgatctgaaa gatattgtaa atagtcaagt taaagtaaaa ttatatcctg aatttatttc
    10861 aactaagcca gaaaagttag ctattacgca cgataatcaa tatgtggttt atttaactga
    10921 aattggtgtg cagttgggta agggcgatga attcgccaat gcagtaatga aagaaatgaa
    10981 aactgcggtt gaaaaagaag acggcatctt ggcaatgctt gctggtacta ttatgaatca
    11041 accgaatgaa tggttttcat tagaagtata caaaactgaa gaaacatact acgaggaaca
    11101 tcttaagact agacacttaa aaaaatatct agaagctacc aagtatgtgg tagaaagtaa
    11161 aggtcttcac ctacttaaac ctgattgtat aatggatcaa ggataaattt tctatcgacc
    11221 ataagaaaaa gcaagttatt tagttgaaaa ataacttgct ttttgaatta tttgcaattg
    11281 tttcgattct ttactttaac agggagaggc ttattaacta acgtagagct gatagccatg
    11341 attcctgcag ttgctaaggc aactgtaatg agtattaatt taatcaaatt cattttcctt
    11401 tcgataagtt atatataatc taacaattaa tcttaagaat ttgtattaaa aattaatagg
    11461 atgattaaga ataaagctat gcaagattaa atttaccaag taaaattata ttagagtcaa
    11521 gtctaatgta atccctgagc caattaattt attaaagtaa gttaattagc tttttttgta
    11581 tgaaaatata aaaaattacg taattatgat tatgtaaact aatcttcagc gatgaatttg
    11641 tcataaatag tcttaatcac tgtttcttca tctttatgtc tagtcccaat cataattgat
    11701 atctgtgagg caccttggtt gatcatctga atagagaggt cttttttacc aagaggctag
    11761 agaatactgg cacaaagggt caatttatcc ttcatccctt cacccccgac cattgtaata
    11821 gcgtaatcat ttatccattg catttgatct ggatttaaac tagtttggat ttcattacag
    11881 ataacgtcat ttaatacatc tttcttaaaa attacactta gatcatcaat actagacggc
    11941 atgtgctcat aagatacatg atgacgattg aaaatttcca ttagctttag tgtgaaacca
    12001 gcacctttgt tcaacatata ttttctcaaa taaagtgctg caaagttctt gcctccagca
    12061 ataccagtta ttgttttctt agccgtaaaa ccttcctctg gcacaattaa agtgccaggt
    12121 ttttccggag cattcgtgtt tttaacgtta actggaattt caccttggat ggcgggaatt
    12181 agcgcttcat catgaaaaac ggaaaagcca gcatatgata gttctcgcat ttcttggtag
    12241 gtcattttct taataggctt gggatgatcg atgatgtggg gattggaaga aaaaatagca
    12301 tcaacatcag taaagttttc atataagtta gcgttaaatc cgcgagctag aatagcacca
    12361 gtaatatcag aaccacctcg tgaaaatgta gaaatatgtg ctggtggagt aataccgtaa
    12421 aaacctggaa agataatgcg ctcatcttta tttagtttga tacgttttaa attaacgtat
    12481 gtctcaggat tgacttcagc attattaggg gttcgagtaa ctattaagcc cacatcttta
    12541 ggctccaaaa aacgcgtttt gatgccttga tgattaagaa ttttagtaat tagcatggcg
    12601 tttaagcgtt caccatgtgc cttaaaggta gccattctat aataatcaag tttaggtaaa
    12661 gttaataata ggcgtttaat ttcgcttagt tctttttcat gtaaattgaa atattgagca
    12721 attagttcat agcgtttgaa aattttattg attaattgcc gaagaaaaca cgggatttta
    12781 atcccgtgat gaatccggcc ttttttagtt tttttgct
//
