LOCUS       c00004_JACSUF0..       23227 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JACSUF010000012.1 Streptococcus thermophilus strain S72 202-S72-12,
            whole genome shotgun sequence.
ACCESSION   JACSUF010000012
VERSION     JACSUF010000012
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 00:40:05
            Original ID  :: JACSUF010000012.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 231619
            Orig. end    :: 254846
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23227
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[241619:244846]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13227
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..23227
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..23227
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             complement(1061..2155)
                     /locus_tag="ctg4_261"
                     /transl_table=11
                     /translation="MSKRAVLMMTFGSPEEITYEGVAEFFTNIRRGVRPEPHKIQTLHD
                     NYLRIGGTPLQRITREEVDLVASALGEQVSVYFANKFSRSFITDVITQMENDGIEECLC
                     LILEPHYSYYSVMGYEKFLESEHIRFQIIKDWYREPSLLHYWADEIRKILDQIGDDSYK
                     VIFSAHSVPVLALDFGDPYIDQIYDNSRLIAEDLGLREEQYTNTWQSESDIGIPWIKPD
                     VLEYLRDEREHPDHYIFVPIVFISEHIEVLFDNDVECKELCQELGVAYHRPPMPNRDPR
                     LIKALLSAIQSHIDGDYSYYQPQLETFDELETPSSTGQILDEEKDIQMPDFVKKLIAKK
                     GLENVKMPYLFKKMLEKKYGKKYD"
     CDS             complement(2267..3163)
                     /locus_tag="ctg4_262"
                     /transl_table=11
                     /translation="MSSKYAVWLAFFLNLSFAIVEFIAGGIFVSSAVLADSVHDLGDAL
                     AIGLSAFLETISNREEDSRYTLGYKRFSLLGALVTAVILMTGSGMVILENVSKLFHPQP
                     VNDEGLLWLGIIAISVNLLASLVIRKGQTKNESILSLHFLEDTLGWLAVILMAIVLRFT
                     DWYILDPLLSLAISFFILSKAIPRFWSTLKIFLDVVPEGVDIKQVKNDLEQLDNVASIN
                     QLNLWTMDGLEKNAIVHVCLEHVKHIEVCKESIRDLLKESGFQNVTIEVDEDLATHQAH
                     KRNIEELEAESEQQHHH"
     CDS             3261..3836
                     /locus_tag="ctg4_263"
                     /transl_table=11
                     /translation="VYVTEQFVYSVHMTAQDRRITKTRKAIYQAFLYLLNQKDYEAITV
                     QEIIDLADVGRSTFYSHYESKELLLDELCQKLFHHLFERTQYLSPQDYLAHIFQHFKKN
                     QDHVTSLLLSKNDYFIRQLRKELEHDVYPMVADELIQSHPNIPHSYLKHLVVTNFIETL
                     TWWLKKGKSYSEQEVVQFYLEILNVASN"
     CDS             3875..4060
                     /locus_tag="ctg4_264"
                     /transl_table=11
                     /translation="MLLLILLGIFTAFLSLAFALLHLMASLSELRKHKNTGSIISVVGK
                     TTVGIIELFECRQKVP"
     CDS             4104..4268
                     /locus_tag="ctg4_265"
                     /transl_table=11
                     /translation="MRLIKNNTELIGIKDQNIKISLVFETDTHIEIQAKLDYPCSIMSS
                     LPRKKDDQI"
     CDS             4255..5358
                     /gene_functions="other (smcogs) SMCOG1206:transposase
                     (Score: 365.4; E-value: 6.1e-111)"
                     /gene_kind="other"
                     /locus_tag="ctg4_266"
                     /transl_table=11
                     /translation="MIKYDFQKNSKISLLEQAGTPTLLRLKKRRFQCKSCRSVTVAETS
                     IVEKNCQISNLVRQKVTQLLTEKVSLTDIARRLRVSTSTVYRKLDQFTFKEHYDKLPAV
                     MSWDEFGFKKGELAFVAQNYEINEPITILDNRHQTTIRNYFLKYPLKVRQQVQFITMDM
                     SGAYIPLARKLFPNAKIVLDRFHIIQHLGRAFLKTRIAIMNQFDKKSLPYRALKNHWRL
                     FQKDSRKLSLNSFYSKTFRQTLAPHEVVAKTLVFSKELTDYYTLYQLLLFHFQEKRVDE
                     FFELIEENRSKVNHYFQTVFRTFLRQKQYIKNALETDYSNAKLEATNKLIKDIKRLGFG
                     FRNFINFKKRVFITLNIHKKKDLSGPL"
     CDS             complement(5417..6136)
                     /locus_tag="ctg4_267"
                     /transl_table=11
                     /translation="MSEAIKLFQYNTLGALMAGLYGGTLTVGELLEHGDLGLGTLDSID
                     GELIVLDGKAYQAKGSEGKVEVVEVSPDEKVPYAAVVPHQAEVIFRQRYEMTDKELEDR
                     IESYYDGVNLFRSIKIKGHFKHMHVRMIPKSNADIKFADVATRQPEYEVDDISGTIVGI
                     WTPEMFHGVSVAGYHLHFISDDLTFGGHVMDFVIENGIIEVGPVDQLDQRFPVQDRQYL
                     FAKFNVDEMRKDITKAE"
     CDS             complement(6152..7828)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 504;
                     E-value: 9.2e-153)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_268"
                     /transl_table=11
                     /translation="MSEEKQLYGADLVVDSLINHDVEYVFGIPGAKIDRVFDTLEDKGP
                     ELIVARHEQNAAFMAQGVGRITGKPGVVLVTSGPGVSNLATGLVTATDEGDPVLAIGGQ
                     VKRADLLKRAHQSMNNVAMLEPITKYAAEVHDANTLSETVANAYRHAKSGKPGASFISI
                     PQDVTDAPVSVKAIKPMTDPKLGSASVSDINYLAQAIKNAVLPVFLLGNGASSEAVTYS
                     IRQILKHVKLPVVETFQGAGIVSRDLEEDTFFGRVGLFRNQPGDMLLKKSDLVIAIGYD
                     PIEYEARNWNAEISARIIVIDVEPAEVDTYFQPERELIGNVEASLNLLLPAIQGYKLPE
                     GSVEYLKGLKNNVVEDVKFDRQPDEGTVHPLDLIEVLQEQTDDDMTVTVDVGSHYIWMA
                     RYFKSYEPRHLLFSNGMQTLGVALPWAISAALVRPKTKVISVSGDGGFLFSAQELETAV
                     RLKLPIVHIIWNDGHYNMVEFQEEMKYGRSSGVDFGPVDFVKYAESFGAKGYRATSKAA
                     FASLLQEALAQAVDGPVLIDVPIDYKDNIKLGETILPDEFY"
     CDS             complement(8082..9254)
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 61.4; E-value: 1.2e-18)"
                     /gene_kind="transport"
                     /locus_tag="ctg4_269"
                     /transl_table=11
                     /translation="LKIKKYAALSIYFNRFSSLISEYGYTILINILLSRISVQLVMYFW
                     VVKCLAAIVTNRINISNSKLSRKYLLILLEITKAILLFLLGFGLNHIIVLLVVFIIEVV
                     NVLFSSLLYSCVPIIIDKDSLIKFNARYTSIGSVSYFLAPLFVGLFINKSHFLLFAVYA
                     LLLIVGATSLLFLPNISTLNLKEERKKQNLNITLFNILRSKKIALVLLSGVIVGSIGVV
                     YDTYEVVYLTKYLGISDSMYSFSLSFLAVSFLVMSFLLSFVKQISSHMKAFALGLSFYV
                     LYLLLFSTSSNIYTVLMSYVFLAIGQTMMGIIETNYFQLSLNMKELQKLYIYSETLHSV
                     FSGIAVLVIGSFAFLSSHLVLVFRSLAVFALFILLCYCVFVNLKKLSIDK"
     CDS             complement(9261..10004)
                     /locus_tag="ctg4_270"
                     /transl_table=11
                     /translation="MKILSIIYDGGSRIPGARFAPTKYYQEAMLYDRKDSDIITINLGN
                     QDLFSIDLESLSRTIAESKVQIALGGDHSVTYLLAKATVREGAYLIVLDAHLDYFKDFE
                     SVVKNWNFLSFLTDIFEKIIIIGERNFEFPSSFDNKIIILSMEEYWLNKSRVLKKLDSY
                     IDESKDIYLSIDIDVLDPSVFDSVSYPIIGGFQMNDFLGIISKILCSDKVYFCDIVEYN
                     PMVGSDNAHIFYQMIQFVKSKLRRI"
     CDS             complement(10001..11098)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_271"
                     /sec_met_domain="PF04055 (E-value: 3.3e-21, bitscore: 70.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.1e-09, bitscore: 33.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 3.6e-11, bitscore:
                     37.6, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 9.7e-09, bitscore: 29.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYQFSLKKFSDSKSQVIKNVIDFLNNNEISLSKTNTKIVEFSTKI
                     PLKVIQIEVTNKCNLRCMHCYLPDYSKELDRKKISSIVYEAKQLGVMDVDFTGGEPLLL
                     QGLSEIIEEVLKEGMCTTIFTNAVYIPEDFKILIQRYDGIRLKVSLDGWNETIHDSIRG
                     RGTFKRTIKNIEYFRSLGVPVTVNVVLNNKNISGVKYFLELFDRLDVKYAFDRFLPFER
                     NNRLSISDEEFNNAILCIPNIQANCNNISESTFESFYCGAGNSYVFINSSGDVGFCPTL
                     SSTKFCGGNINEKTLNDIWINSKFFNHIRNVRCKYYNECPANYVCQGGCRSRAQFFGGS
                     IGSPDIQECKLAYNLTGIKPKSMSL"
     CDS             complement(11300..11449)
                     /locus_tag="ctg4_272"
                     /transl_table=11
                     /translation="MQVSDAIAQIELAEEEVVSSGLSIDIMEIKPSVATELIDGLKGHC
                     PPSV"
     CDS             complement(11588..12310)
                     /locus_tag="ctg4_273"
                     /transl_table=11
                     /translation="MRIIKFPEQISEDIIHYTFLDDIISYNCEKCRGSCCHVNNSLLLD
                     AKTASFLKRTYLKDFIVSDDSVSLLSCGKKCWFHSELGCTINDLGLNKPLTCELYPFHI
                     KKIQNFYIVSFTPCPTFQLNLGEGQRYKDIEDVVLRYIKTGVPVFSPSLHVSEERLKYE
                     IEYQNNFKNTLSEYYRTKTADGTTEFKEYEKWYIYYLDFRWGSIPLSYTSSQANQFWNL
                     YKRVCEDVYKKNIIYTNR"
     CDS             complement(12370..13227)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_274"
                     /sec_met_domain="TIGR01716 (E-value: 9.7e-46, bitscore:
                     150.3, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYGKLFKKFRESRGLVLKDITKLGVSVSHISRFERENTDLTIS
                     KFMSALNAINMPIDEFMYAANDFQRDEFNEILEKISLFVSARNVSGMEKLLISQVEKIE
                     KRETFYTLNTILIKIRLQDLSDKSYYDESDIQYLSDYLFSVEYWGCYELLLFANTVDVL
                     NHQTMMLLSREMCKRSEFYKDLPNYRRLHSTMLLNCYIISIERDEYIDALYFEKQLNHS
                     CFTETEIYEKLVFHYSKNLYELKKNRSNKAILEMKKCITAMKLANSENLAIKFENHLSG
                     VLKM"
     CDS             complement(13561..13890)
                     /locus_tag="ctg4_275"
                     /transl_table=11
                     /translation="MKEIKLTPLDKVDRNGFLASYLAERSKKAPEILQHYNNEIECIKL
                     SHKIKQLRENINLTQQELADRMGKSQASIGRIENGTTNPTYKTLEEIAAATNTRLVVDF
                     VPIKN"
     CDS             complement(14005..14250)
                     /locus_tag="ctg4_276"
                     /transl_table=11
                     /translation="MALKLVRKVDRKKDIFELRINTEGIFARSLFFRLEKANEEEDNVA
                     SPTYIITNSFKKKTNKTPSKELKKAIKRKSNYKNKR"
     CDS             14408..14776
                     /locus_tag="ctg4_277"
                     /transl_table=11
                     /translation="MKHKKMKQKRHKLAKERKNVSGEPGELIAKRYFMYLKRFQAVGFL
                     NPLQIRLIAETFAHIPTSYFFDENRNDWWNYYQMEVDYCEILNFQHKKKHLITIRCLCI
                     FYLSKLSIKIMLQAFKNL"
     CDS             complement(14711..15052)
                     /locus_tag="ctg4_278"
                     /transl_table=11
                     /translation="MDITNFIPSQRQAMLERFQQVEALGLGAVRIELKVANPVGIIYEC
                     YIMSGENYFSDQAVVSFRILYEKDLDRISLDVVDIPGRSSLSNYLQLLEIFEGLQHYLN
                     REFAKVKNT"
     CDS             complement(15458..17290)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190:GTP-binding protein LepA (Score: 550.4; E-value:
                     9.1e-167)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_279"
                     /transl_table=11
                     /translation="MPNIEELKQRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKDGETYIFHLIDTPGHVDFTYEVSRSLAA
                     CEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRTEIEDVIGL
                     DASEAVLASAKAGIGIEEILEQIVEKVPAPQGDVEAPLQALIFDSVYDAYRGVILQVRV
                     VNGMVKTGDKIQMMSNGKTFDVTEVGIFTPKAVGRDYLATGDVGYVAASIKTVADTRVG
                     DTVTLADNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPET
                     SQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSE
                     FPDPTRIDAIEEPYVKAQIMVPQEYVGAVMELAQRKRGDFETMEYIDDNRVNVIYQIPL
                     AEIVFDFFDKLKSSTRGYASFDYELSEYRRSQLVKMDILLNGDKVDALSFIVHREFAYE
                     RGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARTDIKALRKNVLAKCYGGDVSRKRKLL
                     EKQKAGKKRMKAIGSVEVPQEAFLSVLSMDEDEK"
     CDS             complement(17678..17824)
                     /locus_tag="ctg4_280"
                     /transl_table=11
                     /translation="MQTFAKDITLKRLSEPEDVAAAVSFLAGPDSNYITGQTIIVDGGM
                     QFH"
     CDS             complement(18100..18441)
                     /NRPS_PKS="Domain: PKS_KR (3-111). E-value: 4.2e-10. Score:
                     31.5. Matches aSDomain: nrpspksdomains_ctg4_281_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     107.7; E-value: 1.1e-32)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_281"
                     /transl_table=11
                     /translation="MSKVAIVTGAGQGIGFAISKRLVEDGVKVGVLDYDAETAEKAVAE
                     LSEDKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVAPTKSLDTITEEQFQHT
                     FNINIGGVI"
     aSDomain        complement(18109..18432)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_281_PKS_KR.1"
                     /evalue="4.20E-10"
                     /label="ctg4_281_PKS_KR.1"
                     /locus_tag="ctg4_281"
                     /protein_end="111"
                     /protein_start="3"
                     /score="31.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAIVTGAGQGIGFAISKRLVEDGVKVGVLDYDAETAEKAVAELSE
                     DKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVAPTKSLDTITEEQFQHTFNI
                     NIGG"
     aSModule        18109..18432
                     /domains="nrpspksdomains_ctg4_281_PKS_KR.1"
                     /incomplete
                     /locus_tags="ctg4_281"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(18358..18426)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_281_0001"
                     /evalue="1.20E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg4_281"
                     /protein_end="28"
                     /protein_start="5"
                     /score="11.6"
                     /tool="antismash"
                     /translation="IVTGAGQGIGFAISKRLVEDGVK"
     CDS             complement(18652..18945)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163:rhodanese domain-containing protein (Score: 60.2;
                     E-value: 2.8e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_282"
                     /transl_table=11
                     /translation="MDIAQIQSELAQDGLLIDVRTPEEYAEGHVKDALLIPHTQFFTAD
                     IPAKKDASIYLYCKMGSRAEFAAGVLKERGYTKVTTLGGLGDMEALGFKFEK"
     CDS             complement(18947..19375)
                     /locus_tag="ctg4_283"
                     /transl_table=11
                     /translation="MKVGNMQKTFFIIKPDAVKRHLIGQVLDRIERRGFVIERMEMLML
                     DEERLKEHYAQLADKPFFPSISEFMMSGPAVIGIMSGPGVIKSWRDMMGATNPGDAAPG
                     TIRGDFATAPDGDMIPNIVHGSDSEESAAREIKIWFGE"
     CDS             19686..20477
                     /locus_tag="ctg4_284"
                     /transl_table=11
                     /translation="VADQKANGIDILTDGKFGRSMWHLDFVWGLKGIERYIAEHGYTFK
                     DHDGGQYETRKDIGIRITEPLSGKNHHYLDIYKLVKAEAGDEDTKQTIWGPAHAYTELA
                     IFDRLAVPGQVYETNEELKKGLINAYKEFLDEYKAVGGKIVQFDDCLWELFDPSSPTSF
                     YSDGNGDLAELADEFVAINNEVVDYTHELGLTVWTHNCRGNYEIRSAAEGTYEDIAKKF
                     LAEQHYDRFFLEWDSDTAGDIKALEALKDSKAEVVFGLLSS"
     CDS             complement(20742..22085)
                     /locus_tag="ctg4_285"
                     /transl_table=11
                     /translation="MSQSKADYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQ
                     HKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEAHRVPAGGAMAVDREG
                     YAEAVTAEIESHPLIEVIRKEITEIPDDAITVIASGPLTSDALAEKIHELNGGDGFYFY
                     DAAAPIVDKATIDMNKVYLKSRYDKGEAAYLNCPMTKEEFMAFYEALTTAEEAPLNSFE
                     KEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPEDYMGPRDGDFKTPYAVVQLRQDN
                     AAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLKQTFQS
                     KSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKGEDEVIFPHTTAIGSLPYYVTH
                     AESKHFQPMNVNFGIIKELEGPRIRDKKERYEKIAERALKDLQTFIDA"
ORIGIN
        1 atttataact tgtcgtaaag actcggcctg gattgatgtc gccatcaaga acagctttta
       61 acaaaacttg tttatcatag gttgtgacag aggctacccc tcccgccact aaaatatttt
      121 gggcaaaggt cgaaccaagg gaacggttat tataatgagg cacaccgaca aatcccatac
      181 gaccaccgtt atggaggaca ccaagagctt gttctactgc tgcttcagta ccgacacatt
      241 cgagagctgc atctgctcct cccccgagga tttcacggac tttgtcaatg cctttttcgc
      301 cacgctcagc tacaaccgca gtcgcacctg actccaaagc catcttttga cgatcttcgt
      361 gacggctcat aaggacaatt tgagaagctc cacgcatctt agatgcaatg acagcacatt
      421 gaccaacagc cccatctccg ataacgacaa ccttatcacc cttttgtaca ttagccacac
      481 gcgcagcatg gtaacccgtc ggcataacat cagcaagtgt caaaagtgac ttgagcatgc
      541 cttcgctata atctgagggt tgcccaagaa ttttgacaag ggcccagttg gcaaagtgga
      601 aacggatata ctcagcctgc acgccctcag accagttatt acctgagtgg ttatcacaag
      661 agccgtcaaa accagctcga caagcatcac actgaccaca cccatgtgtg aaaggtgcaa
      721 tgacaaagtc tcctggtttt accgtagtaa cttgctcacc aacttcttcg acaattccga
      781 tagcctcatg accactattt ctatgtccct cttccatttc cggattacgg taactccaaa
      841 ggtcagatcc acaaacgcaa gtacgtacta tcttgataat ggcatcatct gctgccacga
      901 tttgcgggcg atcaatttct gccagcccca cttgtccagc tttggtataa actgctgatt
      961 tcatatatct acctctattt ctttagttat agttagtata cacttttagg caagctttag
     1021 ctcacatcat gccctccaaa ttactttcaa acaatagcaa ctaatcatat ttttttccat
     1081 acttcttttc aagcattttc ttaaatagat atggcatctt gacattttct agaccttttt
     1141 tagcaatcaa tttcttgacg aaatcgggca tttgaatgtc cttttcctca tccaaaatct
     1201 gacctgtgct agaaggagtt tccagctcat caaaggtctc aagctgaggt tgatagtaac
     1261 tatagtcacc gtctatatga gactgaatag ccgaaagaag ggccttgatt aaacgaggat
     1321 cgcgatttgg catgggaggt ctgtgatagg ctacacctag ctcttggcaa agttccttac
     1381 attccacatc attatcaaaa agaacctcaa tatgctcact aataaagaca atagggacaa
     1441 aaatatagtg gtctgggtgt tcacgctcat ctcgtagata ttctaagaca tcaggcttaa
     1501 tccaaggaat acctatatca ctctcactct gccaagtatt agtgtactgc tcttctctaa
     1561 gtcctaaatc ctccgcaatc aagcgactat tatcataaat ctggtcgata taagggtcac
     1621 caaaatctag tgccaaaact gggacactgt gagctgaaaa aatcacctta taactgtcgt
     1681 ctccaatctg atctaaaatc tttcggattt catcagccca ataatgaaga agagaaggtt
     1741 cgcggtacca gtccttgata atttggaacc taatatgctc actttctaaa aatttctcat
     1801 atcccatgac agaatagtaa gaataatggg gctctaaaat caagcacaaa cattcttcaa
     1861 ttccgtcatt ctccatctgt gtaatcacat ctgtaatgaa agatcgtgaa aatttattgg
     1921 caaagtaaac cgacacttgt tctccaagag cagaagcaac caaatccacc tcttctctgg
     1981 ttatcctttg gagtggagtt ccaccaattc ggaggtaatt gtcatgtaaa gtctgaattt
     2041 tatgtggttc aggacgaaca ccacgccgta tattcgtgaa aaactccgct actccttcat
     2101 aggtaatctc ttctggtgac ccaaaggtca tcatcaacac agctctctta ctcataatta
     2161 atccttgttc tacatttgtt ctattttatc atgaaaagga tcactttagg gaacttggta
     2221 tcaaaataac tcttaaaggt agactctaag agtttaaaaa caaaccttaa tgatggtgtt
     2281 gctgctcact ttctgcttct agctcttcga tatttcgctt gtgagcttgg tgggttgcca
     2341 agtcttcatc aacttcgatg gtgacatttt gaaagccact ctctttgagc aagtctcgga
     2401 tagactcttt acagacctcg atatgtttga catgctccag acaaacatgg acaatagcat
     2461 ttttctccaa gccgtccatg gtccaaagat taagctgatt gatactagca acattatcca
     2521 actgctctaa gtcattctta acttgcttga tatctacccc ttctggcaca acatccagga
     2581 aaatcttgag cgtgctccaa aaacgtggaa tggctttgga cagaataaag aaggaaatag
     2641 caagagacaa gaggggatct aggatatacc agtccgtaaa tcggaggaca atggccatca
     2701 ggatgacagc caaccaacct aaggtatctt ccaaaaaatg caggctgaga atagactcat
     2761 tcttggtctg acccttacga atgaccagac tcgccagcag attgacactg atagcaataa
     2821 ttcccaacca aagaagccct tcgtcattga cgggttgtgg gtggaaaagc ttgcttacat
     2881 tttctaaaat caccatacca gaccctgtca tcagaatgac tgccgttacc aaagccccta
     2941 ataagctaaa acgcttgtag cctagggtat agcgactatc ttcttcacga ttggagattg
     3001 tttctagaaa ggccgagagg ccaatggcta gagcatcccc caagtcatgg acagagtcag
     3061 cgagaacagc actggaaaca aagattcccc ctgcaataaa ctcaacaatg gcaaagctta
     3121 gattcaagaa aaaagccaac cagactgcat attttgaact cattttttac cttcctttgg
     3181 tataatagat tcacgaacat catattcaat atctattatc caatactacc aacagaaagg
     3241 ataggggcaa accgttcgct gtgtacgtta ctgaacagtt tgtttatagt gtccatatga
     3301 ctgcacaaga tcgtcgcatt accaagacta gaaaagccat ctatcaagct ttcttgtact
     3361 tacttaacca aaaagattat gaggccatca ccgttcagga gattattgac ttggctgatg
     3421 tggggcgttc gaccttttac agccattatg agagcaaaga gttactactg gatgagctct
     3481 gccaaaagct ctttcaccat ttgtttgagc gtactcaata cctctctcca caagactacc
     3541 tggcccatat ctttcaacat ttcaagaaaa atcaagacca tgtaaccagt ctcttgcttt
     3601 caaaaaacga ttattttatc cggcagctgc gaaaagaact ggaacatgac gtctatccaa
     3661 tggtagctga tgaactgatt caatcacacc ccaacattcc tcactcatat ctcaagcacc
     3721 tggttgtaac caacttcatt gaaaccctga cctggtggtt gaaaaaaggc aagtcctaca
     3781 gcgagcagga agtagtccag ttttatttgg agattttaaa cgtcgcttct aactaaggtg
     3841 cgactttaca tcatgtatca tagaaaggaa aactatgctc ctcctcattc ttcttggtat
     3901 tttcacagct ttcttatccc ttgcttttgc tcttcttcat ttaatggcca gtctttcaga
     3961 attaagaaag cacaagaata ctggctctat aatttctgta gtgggtaaaa ctactgtagg
     4021 gattatagag ctttttgagt gcagacaaaa agtcccataa gaactataat gaaaagcaac
     4081 caaaccatca ttaggaagaa cttatgagac ttattaagaa taacacagaa ttaatcggaa
     4141 tcaaagacca aaatatcaag atttcacttg tttttgaaac tgatactcat atcgagattc
     4201 aagcaaaact tgattaccct tgctccatca tgtcctcact gccaaggaaa aaagatgatc
     4261 aaatatgact ttcaaaaaaa ctctaaaatc tctcttctcg agcaagcggg aacgccaact
     4321 ctactacgtc tgaaaaaacg tcgtttccag tgtaaaagtt gtagaagtgt cacggtagct
     4381 gagacatcta tcgttgagaa aaactgccaa atctccaatc tagtccgaca aaaagttaca
     4441 caactcctaa ctgagaaagt gtcactaact gatattgcaa gaagacttcg cgtgtcgaca
     4501 tccactgtct atcgtaagct tgatcagttt actttcaagg aacattatga caaactccct
     4561 gctgttatgt cctgggatga gtttgggttc aagaaagggg aattggcttt tgtggcgcag
     4621 aattatgaga taaacgaacc cataaccatc cttgataatc gccaccaaac tactatacga
     4681 aactactttt tgaagtatcc attgaaagtc cgacaacagg tacagtttat cacgatggat
     4741 atgtctggag cttatattcc actggctcgc aagctctttc caaacgcaaa aatcgttctt
     4801 gatcgtttcc acatcatcca gcaccttgga cgtgcctttt taaagacaag aattgcaatt
     4861 atgaaccagt tcgataagaa gtcactaccc tatcgagccc tgaaaaatca ctggcgactc
     4921 ttccaaaagg acagccgtaa actatctctc aactcttttt attcaaagac tttccgccaa
     4981 actttagcac cacatgaagt tgttgcgaag acactagtct tttcaaaaga gcttactgac
     5041 tactatacac tttatcagct tttgcttttt cactttcagg agaagagagt agatgagttc
     5101 tttgaactga tagaggaaaa taggagtaag gtcaatcatt attttcaaac tgtctttagg
     5161 acttttctta gacagaagca atacatcaaa aacgcactag aaacggacta ttcaaacgca
     5221 aaacttgaag cgactaataa gttgatcaaa gacatcaaac gcttgggctt cggttttaga
     5281 aactttatca actttaagaa gcgtgtcttc atcacactga acatacataa aaaaaaggac
     5341 ctatccggtc ctctctagat gttagctttt cgttacccac tacagttgac aaagagacag
     5401 tatcttattt atatgcttat tcagccttag taatatcttt acgcatttca tcaacattga
     5461 atttagcaaa gagatattga cggtcttgaa ctgggaagcg ttgatcgagt tggtcaactg
     5521 gtccaacttc aataatacca ttctcgataa caaaatccat aacgtgacca ccgaatgtca
     5581 agtcatctga aataaaatgg agatggtaac cagcaacact cacaccgtgg aacatttcag
     5641 gtgtccagat accaacgatt gtacctgaaa tatcatctac ctcatactca ggttggcgag
     5701 tggcaacatc agcaaactta atgtccgcat ttgattttgg aatcatgcgc acgtgcatgt
     5761 gtttaaaatg acctttgatt ttgattgaac ggaaaagatt gaccccatca tagtatgatt
     5821 caatacgatc ctcaagttct ttatcagtca tttcataacg ttgacggaag ataacttcag
     5881 cttggtgagg tacgactgct gcatagggaa ctttttcatc aggagaaact tctaccactt
     5941 cgactttacc ttcagagcct ttagcttgat aggctttacc gtcaagaaca atcaactcac
     6001 catcgataga atctaatgtt ccgagaccca agtctccatg ctctaacaac tctccaacgg
     6061 ttaaagtacc tccataaagc ccagccatca aggctcccaa agtattatat tgaaataatt
     6121 ttatggcttc agacatgtct acaccctctt tttagtaaaa ttcatctggc aaaatagttt
     6181 cgccgagttt aatgttatct ttatagtcaa ttggaacatc aataaggact ggtccatcta
     6241 cagcttgagc caaggcttct tggagcaagc tagcaaacgc tgctttactt gttgcacgat
     6301 aacctttggc tccaaagctc tcagcatatt ttacaaaatc tacaggacca aagtcaaccc
     6361 cagatgaacg accgtacttc atttcttcct ggaattccac catattgtaa tgaccatcgt
     6421 tccagataat atggacaatt ggcaatttca aacgaactgc tgtttccaat tcttgtgctg
     6481 agaagaggaa accaccatca ccagaaacag aaatcacttt tgtcttagga cgaaccaaag
     6541 ctgcagagat agcccatgga agagcaacac ctagcgtttg catcccattt gagaaaagca
     6601 aatgacgtgg ttcatacgat ttgaaataac gtgccatcca aatatagtga ctaccaacat
     6661 caaccgtaac agtcatatca tcatctgttt gttcttgcaa aacttcgatt aaatctagcg
     6721 gatgcaccgt accttcatca ggctgacggt caaacttaac atcctcaaca acattgtttt
     6781 tcaaaccttt aagatattca accgaacctt caggcaattt ataaccttga atagcgggca
     6841 aaagcaagtt taagctcgct tctacattac caatcaattc acgttccggt tggaagtaag
     6901 tgtccacctc ggccggctca acatcaataa cgatgatacg tgctgaaatt tcagcattcc
     6961 agttacgtgc ttcatattcg attgggtcat aaccaatggc aataactaag tcggattttt
     7021 taagcaacat gtctccgggt tggttacgga aaagacctac acgaccaaag aaagtatctt
     7081 cttcaaggtc acgtgacacg ataccggcac cttggaaagt ttcaacaact ggcaatttaa
     7141 catgcttcaa aatttggcga atagagtaag ttacggcttc tgatgaggca ccattcccca
     7201 aaagaaagac tggcaacact gcatttttaa tggcttgtgc gagatagtta atatcagaaa
     7261 cagatgctga accaagtttt ggatctgtca taggcttaat agccttaaca ctgaccggag
     7321 catccgtcac gtcttgagga attgaaatga agcttgcacc tggtttccct gacttagcgt
     7381 gacgataggc attagcaacc gtttcagaaa gggtgttagc atcatgtact tcagcagcat
     7441 atttggtaat tggctcaagc atagcaacgt tattcattga ttggtgggca cgtttcaaga
     7501 gatctgcacg cttaacctga ccaccaatag caagaacagg gtctccttca tccgtcgctg
     7561 ttaccaaacc agtagccaaa ttggagacac ctggaccaga tgttaccaat actacacctg
     7621 gtttcccagt aatacgtcca acaccttgag ccataaaagc agcattttgc tcatgacggg
     7681 caacaatcaa ttcaggtccc ttatcttcca aggtatcaaa aaccctatcg atttttgcgc
     7741 ctggaatccc aaagacatac tcaacatcat ggttgatcaa actatcaacc actaaatctg
     7801 caccatacaa ttgcttttct tctgacatga acacagtcct tctagcccta aaatggtaga
     7861 gccaactttc ctttcaagta taagtcacaa agtgtcaaag tctgctcgtt ttttcacaaa
     7921 ctttcatcaa ttcacaattc tgttatcatt atagcacagt tttcagacaa tcttgtgaaa
     7981 aaaggcagac taggtgacta aaaaaagaca aacactcaaa atagcgtttg tctactttat
     8041 aaattaacta tctcatttgc ttgttttctg atttataaat attacttatc aatgcttagt
     8101 tttttgaggt ttacaaacac acaataacac agaagaataa acagagcaaa aacagcaaga
     8161 cttctgaaaa ctaaaacaag atgactactt aaaaaggcaa aacttcctat tactaaaaca
     8221 gcaatgcctg aaaatacaga atgtaaggtc tccgagtaaa tatatagttt ctgtaattct
     8281 ttcatgttaa gtgacaactg aaaataattg gtttcgatta tccccatcat tgtctgacct
     8341 atcgctagaa aaacataact cattagtact gtataaatgt tcgaagatgt actaaataaa
     8401 agtagatata gaacataaaa tgaaagacct aaggcgaaag ctttcatatg agaacttatt
     8461 tgtttcacga agctaagaag gaagctcatt actaagaatg aaactgctaa aaatgataag
     8521 gaaaaggaat acatagaatc actaataccg agatactttg ttaaataaac aacttcataa
     8581 gtatcataaa caactccaat tgatcccaca ataactccag ataatagaac taatgcaatt
     8641 tttttggatc tcagaatgtt aaataatgta atgtttaaat tttgtttttt tctttcttct
     8701 ttcaaattta aagtcgaaat atttggtaaa aataaaagac tagtagctcc cactatcaaa
     8761 agaagagcat aaactgcaaa caataaaaag tgacttttat taataaataa accaacaaac
     8821 aacggtgcta aaaaataaga tactgaacca atgcttgtat acctagcgtt aaacttaatc
     8881 aatgaatcct tgtctataat aattggtaca caactatata ataaactgga aaacaataca
     8941 ttgacaacct caattatgaa tacaactaat aggacaatta tatggtttaa tccaaaacct
     9001 agtaagaaaa gtaagattgc ctttgtaatt tctaacagaa taagcaggta ttttctgctc
     9061 agtttactat ttgagatatt aatcctattt gtaactattg cagctaaaca ctttaccacc
     9121 caaaaataca taactaattg cacagaaatt ctagacaata gaatgttgat caagatagta
     9181 taaccatact ctgagattaa cgatgagaaa cgattaaaat aaatactcaa tgctgcatat
     9241 ttttttattt tcaatatttc ctatatcctc cttaattttg atttaacaaa ttgaatcatt
     9301 tggtaaaaaa tgtgagcatt atcacttcca accatcggat tgtactcaac tatatcacaa
     9361 aaatatacct tatcagaaca taaaattttg gaaattattc caagaaaatc gttcatttga
     9421 aatcctccaa taataggata tgatactgaa tcaaaaacag atggatccaa aacatcaatg
     9481 tctattgata agtaaatatc ttttgactca tcaatataac tatctaactt tttcaaaact
     9541 ctactcttat ttaaccaata ctcctccatt gagaggatga ttattttatt atcaaatgaa
     9601 ctaggaaact caaaattcct ttccccaatg ataattattt tttcaaaaat atcggttaaa
     9661 aaacttaaaa aattccaatt ttttacaaca ctttcaaagt ctttgaagta atctaaatga
     9721 gcatctaaaa caattaaata tgctccctct cgaacagtgg cctttgctaa tagataagta
     9781 actgaatgat ctcctcctaa agcaatctga actttagatt cagcaatagt tcgacttaga
     9841 ctttctaaat caatagaaaa taaatcttga ttacctaaat taattgtaat tatatcagaa
     9901 tctttcctat catataacat cgcttcttga taatattttg tgggtgcaaa tctcgctcct
     9961 ggaattctac ttccaccatc ataaataata gataatattt tcataaactc attgactttg
    10021 gcttaatccc agttaaatta tatgctaact tgcactcctg tatatcggga ctcccaatag
    10081 aacctccgaa aaactgagct cgacttctac acccaccttg acaaacataa tttgcagggc
    10141 attcattata atacttacat cgtacatttc gaatatgatt gaagaacttc gaattaatcc
    10201 aaatatcatt taaagtcttt tcattaatgt tacctccaca aaatttagtg gaggataatg
    10261 tcggacaaaa tccaacatca cctgacgaat ttataaacac ataagaattg ccagcaccac
    10321 aataaaatga ttcaaatgtg gattcggata tattattaca atttgcttga atattgggaa
    10381 tacacaaaat agcattattg aattcttcat cactaattga tagtcgatta ttcctttcaa
    10441 aaggtaaaaa cctatcaaaa gcatatttca catctaatcg atcaaacaac tccaaaaaat
    10501 acttcactcc actaatattc ttgttattca aaacaacatt aacagtaaca ggtactccta
    10561 aactcctaaa atattcaata ttcttaattg ttctcttaaa tgtacctctt cctctaattg
    10621 aatcatgtat tgtttcattc caaccatcta aactaacttt tagtcttata ccatcatatc
    10681 tttgaatcaa tattttaaaa tcttcaggaa tatatacagc atttgtaaaa attgttgtac
    10741 acattccctc ttttaatact tcctcgataa tttcacttaa tccctgtaat aataatggtt
    10801 cgcctccagt gaaatcaaca tccattactc ctagctgctt agcttcatat actatacttg
    10861 aaattttctt tctatcgagc tcctttgaat aatcaggtaa ataacaatgc atacatctta
    10921 ggttacattt gttcgtgacc tcaatctgta tcacttttaa tggtattttc gttgaaaatt
    10981 caacaatttt agtgttggtc ttagagagtg atatttcatt gttatttaga aaatctataa
    11041 cattttttat tacctgactc tttgaatcag aaaacttttt caatgaaaat tggtacataa
    11101 attttaaagc taaaaatgta gctaaattta atgaaaatag tttattattc ctattattcc
    11161 tgagtattcc ttgcttattg taccaattaa aaaaatcgag taaacattgc tcgtcatatt
    11221 aattccctgc aatcttccaa aaatattaat ataaaaacca aaggattaga aatagactct
    11281 aatcctacaa tcagttctat tagacagacg gtgggcaatg acctttgagt ccatcaatca
    11341 actctgtagc aacagaaggt ttaatttcca taatgtcaat agatagaccg ctagaaacaa
    11401 cttcttcttc tgctaattca atttgtgcaa tagcatcact aacttgcatc gtaatatcct
    11461 ccattattta tttaagaatc aataagtacc cataacaaat catagaaatc attctttatc
    11521 tataaaattt agctgaaaat gctttgaaat tgtcttatta aactgatttg caataataaa
    11581 gtatatgtta tctgttcgta tatatgatat tttttttata aacatcttca caaactctct
    11641 tgtaaagatt ccaaaattga tttgcttgtg aacttgtata agataagggt atacttcccc
    11701 atctaaaatc taaataatat atataccatt tttcatattc tttaaactct gtagtgccat
    11761 cggcagtctt tgttcgataa tactctgata aagtgttttt aaaattgttt tgatactcaa
    11821 tctcatattt cagcctttcc tctgaaacat gcaaagacgg actaaaaact ggcaccccag
    11881 ttttaatata tcgtaaaact acatcctcta tatccttgta cctctgcccc tcaccaaggt
    11941 tcagttgaaa tgtcggacaa ggagtaaaag aaacaatata gaagttctga attttcttaa
    12001 tatgaaaagg atataattca caagttaatg gcttgttcaa gcctaaatca tttatcgtac
    12061 aacccaattc agaatgaaac cagcactttt taccacaact caacaatgaa acactatcat
    12121 cactaacaat aaaatcttta agatacgtgc gttttagaaa acttgctgtc tttgcatcaa
    12181 gtaataaaga attattcaca tgacaacaag atcctctaca cttttcacaa ttataagaga
    12241 taatatcatc tagaaacgta taatgaatga tatcttctga aatctgttca ggaaatttaa
    12301 taattctcat atcaataata tatcatttaa ttttgacact gataatttat accatataca
    12361 caaatccaac tacattttta acactccaga taaatgattt tcaaatttta tagctaaatt
    12421 ctcactatta gccagcttca ttgcagtaat acacttcttc atttctagaa tagctttatt
    12481 gctcctattc ttctttaatt catataaatt ttttgaataa tgaaacacta atttctcgta
    12541 aatctcagtt tccgtaaaac aactatgatt taactgtttt tcaaaataca acgcatcaat
    12601 atactcatct ctttcaatac ttatgatata acaatttaat agcattgttg agtgtaacct
    12661 tcggtagttt ggtaaatcct tgtaaaattc tgaacgttta cacatttctc ttgataaaag
    12721 catcattgtt tgatgattca atacatctac agtattcgca aataacagta gttcgtaaca
    12781 accccaatat tctacagaga ataggtagtc tgataaatat tggatatcag attcatcata
    12841 gtaacttttg tctgataagt cctgtaaacg aatttttatt aaaatagtat ttagagtata
    12901 aaaagtctca cgcttttcga ttttttctac ttgagagatt aataactttt ccatacctga
    12961 cacgttcctt gctgaaacaa ataaactaat cttttctaag atttcattaa actcatctct
    13021 ctgaaagtcg tttgctgcat acataaactc atcaataggc atatttatcg catttaaagc
    13081 tgacataaac ttactaattg tcaaatctgt attttcacgt tcaaagcggg aaatatgaga
    13141 tactgatacg cctaactttg tgatatcttt taagactaat cccctagact ctctaaattt
    13201 cttaaataat tttccataat ctttcataaa aagcacctct tttgcatata cgagaatttc
    13261 ccagataaac ttaaaagtat tatatcatat agtgagatag gaggttaatt tctatgaata
    13321 aagaaagttt tttagctatc ttacttctaa tttttgaaag cattattgta attgctgttg
    13381 gctaaacaaa tagaaaataa agacaccaca aaagttagac tttcgatgtc taacttttgt
    13441 ggtgtagtta aggtatgatg ttgttctcta ataagggtat aatataaaaa agactctatg
    13501 atttctgtag taggtaaaac cactatagag attatagagc tttttgagtg tatacaaaaa
    13561 ctagttcttt attggaacaa agtcaacaac taatctagta ttggttgcag cggcaatttc
    13621 ttccaatgtt ttatatgttg gattagtggt gccattctct atacgtccga tactagcctg
    13681 actttttccc atacgatcag caagttcttg ctgagttaaa ttgatattct ctcttaattg
    13741 tttaatttta tgcgatagct ttatacactc gatttcattg ttatagtgct gtagaatttc
    13801 aggtgccttt ttactccttt ctgccaagta tgaagcaaga aacccgtttc tatccacttt
    13861 atcaagtggt gtaagtttga tttccttcat gtgcatctct ccttaataaa atatagtcaa
    13921 tatccatact aaactttaca gtccagtttt aaaggttgaa tctttttcag cccttaaaac
    13981 tggattgcga gaatccagtt tgtgtcatcg cttgttctta tagttcgatt ttcgtttgat
    14041 agctttcttc aattccttag atggtgtttt atttgttttt ttcttaaagg agtttgtgat
    14101 gatataagta ggtgaagcca cattgtcttc ttcttcgtta gctttttcta aacggaaaaa
    14161 taatgaacgg gcgaaaatgc cttccgtatt aattctaagc tcaaagatat ctttttttct
    14221 atctactttt ctgactaact ttagagccat ggtttctgct ataccgatag cagaaacctc
    14281 tcgtatcctt gcgataacct ttgacgctac agttaagggg agggaatcta aaaacgctgc
    14341 aaattcgtct tcgtcataat aaataaaggt tagtttagag ggggctttat tacttaagga
    14401 aaaagttatg aaacataaaa aaatgaagca aaaaaggcat aaactagcca aagaacgtaa
    14461 gaatgtatca ggtgagccag gagaactaat cgctaaacga tattttatgt atttaaagcg
    14521 gttccaagca gttggttttt tgaacccttt gcaaattcgg ttaattgctg agacgtttgc
    14581 acatattcct actagttact tcttcgacga aaatcgtaac gattggtgga attattatca
    14641 aatggaggtt gactattgtg aaattttgaa cttccagcac aaaaagaaac acctgattac
    14701 aatcagatgt ttatgtattt tttaccttag caaactctcg attaagataa tgttgcaagc
    14761 cttcaaaaat ctctagtaac tggagataat tagacaaact tgagcgacca gggatatcta
    14821 ccacatccaa agaaatgcgg tccaagtcct tttcgtaaag aatacggaag gataccactg
    14881 cttgatcaga aaaataattc tctcctgaca taatgtagca ctcataaatg atgccaacag
    14941 gattcgcaac cttcaactca atacgaactg cgcctaagcc caaggcctcc acttgctgaa
    15001 aacgttccaa catagcctgt cgctgactag gaataaaatt tgtgatatcc atagtggccc
    15061 tcccgacttt ccttttgtat attatagcct aaagctgaga aaaatgcttg cgaagggatt
    15121 cctgataaga ctacccccca tgaatcctca tctagcttct ttatattctc taaagtctga
    15181 ttttatagtg tttatcgtaa tgtagtaagt gtgttctaca tgactaagta caacatattg
    15241 ttgacgacta ccaaaaatct cattggaagt taccttatct gcttttaggt cagtctataa
    15301 ttctgctaca tgctttgtat cgccattccc taaaaagaaa agtatttagt atgatcgtag
    15361 cataaatcct tccacacttt gagaaggtaa attttaaaat cctctttatc ataacttttt
    15421 actaaaatag ccagaacatc acattctact atcattctta tttctcatct tcgtccattg
    15481 aaagcacaga caagaaggct tcttgtggta cctccaccga accaatggct ttcatacgtt
    15541 tcttaccagc tttttgtttt tcgaggagtt tacgtttacg tgaaacgtca ccaccgtaac
    15601 atttagccaa gacgttttta cgaagagctt tgatatctgt acgggcaaca attttttgac
    15661 caatagccgc ttggatagga acttcaaatt gttgacgtgg aataattttc ttaagtttat
    15721 caacgataag ttttccacgt tcgtaggcaa attctctatg gacaataaag ctaagggcat
    15781 cgaccttatc accattaagg agaatatcca ttttcaccaa ttgtgaacga cggtactctg
    15841 acaattcata gtcaaaactt gcataaccac gagttgatga cttcaattta tcaaagaagt
    15901 caaagacgat ttcagcaagt ggaatttgat agataacgtt aacacgatta tcatcaatat
    15961 attccatggt ttcaaaatca ccacgtttac gttgcgccaa ctccataaca gcaccaacat
    16021 actcttgagg aaccataatt tgagctttga cataaggctc ttcaatggca tcaatacgtg
    16081 taggatctgg aaattcagat gggttggaca cttcaagcat ttcaccgtca gtagtgttaa
    16141 catggtaaac tactgatggt gcagtcatga tgagatcgat gttaaactca cgttccaaac
    16201 gctcttggat aacatccatg tgaagaaggc ccaagaaacc acaacggaaa ccaaaaccaa
    16261 gggcttgaga cgtttcaggc tcaaattgaa gactggcatc attcaattgg agcttttcaa
    16321 gagcctcacg caagtcgtta tatttatttg actcaattgg ataaagacca gcaaagacca
    16381 ttgggttcat ttgcttataa ccatgaagtg gttctgcggc tggattatcc gcaagtgtca
    16441 ctgtatcacc gacacgagta tccgcaactg tcttaattga agctgctaca taaccaacat
    16501 ctccagtcgc aaggtagtca cggccaacag ctttaggagt gaaaatacca acctcagtaa
    16561 cgtcaaaggt cttgccatta gacatcattt gaatcttatc gcccgtttta accattccgt
    16621 taaccacacg cacttggagt atgacgccac gatacgcatc ataaacagag tcaaagataa
    16681 gggcttggag aggtgcttcc acatcacctt ggggcgcagg aactttctca acaatttgtt
    16741 cgagaatctc ttcgatacca atgccagcct tagctgatgc aagcacagct tccgaggcat
    16801 ctaatccgat aacatcttca atctctgtac gtacacgctc aggatctgcc gctggaaggt
    16861 cgattttatt gataactggt aagatttcca agtcattatc aagtgccaag taaacattgg
    16921 caagtgtttg tgcttcaatc ccttgagctg catctaccac caagatagca ccctcacagg
    16981 cggcaaggga acgtgacacc tcataagtaa agtccacatg tcccggtgtg tcgataaggt
    17041 ggaaaatata agtctcgccg tctttagctt tgtagttaag ctcaatggca ttcagtttga
    17101 tagtgatacc acgttcgcgc tcaagatcca tactatcaag gagttgtgcc tgcatctcac
    17161 gacttgatac agtctcagtc ttttccaaga tacggtcagc aagcgttgat ttaccatggt
    17221 caatatgagc aataatcgag aagttgcgaa tcttctcctg tctttgtttt aattcttcaa
    17281 tatttggcat tttattcttt cctaattctt acttgtgatt gttaaaaaac gaaccgtcac
    17341 ctcctattat acaaaaaaga caggcatttg cctatctcta atatctgctt tatgactgca
    17401 tttagtcctt cttatttctt aaaattatca ttgtagtgct tattaataat agctgaacgc
    17461 ttgttctcta ttgaactact tgaaaatgga gctaaaccaa aggctagtac aataattccc
    17521 aatagaataa gactaaaaaa tgggtgctca gcaatatagt gtaagatgtc tgatatggga
    17581 atccaccttt aaaaacataa ttatttataa ctatattatc agaaacatta tgttttatca
    17641 agcaaaaaaa gagagccatt cgctctccct tttaacctta atggaattgc ataccaccat
    17701 caacgatgat tgtttgacct gtgatgtagt ttgagtcagg tccagctagg aagctaactg
    17761 ctgctgcaac atcttcaggt tctgacaaac gtttgagggt aatatcttta gcaaaagttt
    17821 gcatacccca ctcatcatct ttaccagcat tttaccaact tcgtgggcaa tgtcaaacat
    17881 cattggagtc ttaacgatac ctggtgcata agcatttaca gttatacctg aatcagctaa
    17941 gtcacgcgcc aaagtttgag taataccacg aactacgaat ttagttccac catatacagt
    18001 taagttagag ttccctacga cacctgcttg taaagttgca ttgataattt taccaccatg
    18061 accaagtgat ttaaattgtg cttgggcagc ttgtgcacct cagataactc caccaatatt
    18121 aatgttaaat gtatgttgaa actgttcttc agtaatagtg tcaagggatt ttgttggtgc
    18181 cacaccagca ttattaacaa caacattcaa gtcgccaaag tgatcaacta ctttttggaa
    18241 agctgctgct acctcagctt gtttagacac atctgctaca acggaaaatg ccttgtcttc
    18301 tgacaactca gcaactgctt tttcagcagt ttcagcgtca tagtccaata ccccgacttt
    18361 aacaccatct tcaaccaagc gttttgaaat cgcaaaacca ataccttgac ctgcacctgt
    18421 aacaatagca acttttgaca tacgaaatcc tcctctacca attgtagtca caagcttaac
    18481 cacaagccct atctcaattg gaatatgcta agttaatcaa gttctggcaa agtcattttc
    18541 ataggctttt tcttaactca tttagaatct taccacttta tgaaagcgtt gttaataatt
    18601 tgtcatgctt tttgaaagca aataagatca ccactagtga ccttatgtgt attatttttc
    18661 aaacttaaac cctagtgctt ccatatcacc taggccacct aaggtggtaa ccttagtata
    18721 tcctcgttct ttcagtactc ctgcagcaaa ttcagcacga gatcccattt tacaatagag
    18781 gtaaatggag gcgtcttttt tagctggaat gtcagctgtg aaaaactgcg tgtgaggtat
    18841 taataaagca tccttaacat gaccttctgc gtactcttct ggagtcctga catcaattaa
    18901 tagtccatcc tgagctaatt ctgattgaat ctgtgctata tccatcctac tcaccaaacc
    18961 aaatcttaat ttctcgagcc gcagattctt ctgaatcaga gccatgaacg atatttggaa
    19021 tcatgtcacc atctggtgct gttgcaaagt ctccacgaat cgttccagga gcagcatccc
    19081 caggattagt tgctcccatc atatcacgcc atgacttaat aactcctggg ccggacataa
    19141 taccaataac tgctggacca ctcatcatga attcagaaat actagggaaa aaaggtttat
    19201 cagccaattg ggcataatgt tctttaagac gttcttcgtc aagcatcagc atctccatac
    19261 gctcaataac gaagccacgt cgctcaattc gatcaagcac ttgaccaatt agatgacgtt
    19321 taacagcatc tggtttaata ataaagaatg ttttttgcat attcccaacc ttcatcgttt
    19381 tctttccatt ttatcataag aagtatcatt ttgcagagct aaaccttgta tagtctaaaa
    19441 ctatatacac agcaagaaat taactatttt tcattagttc ccataagaaa taatatagat
    19501 gtaaatagac atttcgaggt aaatttaatg acaaaatcta aattccaatt agtcggttct
    19561 cttcttcgtc ctgcggatct ccgtaaatac aaggacgaaa tcgagcatcg tgacgacatc
    19621 cagtatcctt tctatgatgc ccttcctggt tatcaagaaa ctgaaactgc atctattaag
    19681 cgaatgtggc tgaccaaaaa gctaacggaa ttgacatcct taccgatggg aagtttggac
    19741 gttctatgtg gcacttggac tttgtctggg gactcaaagg tattgaacgc tacattgctg
    19801 agcatggtta tacttttaaa gaccatgatg gtggtcaata tgaaacacgt aaagatatcg
    19861 gtattcgtat cactgagcct ctatcaggta aaaaccacca ctacctagat atttacaaat
    19921 tggttaaggc tgaagctggt gatgaagata ccaaacaaac tatctgggga cctgctcatg
    19981 cctacactga acttgctatc tttgatcgat tggctgttcc tggacaagtc tatgaaacaa
    20041 acgaagaact caaaaaaggt ttgattaatg cctataaaga attcttggat gaatacaagg
    20101 ctgttggtgg taaaatcgtt caatttgacg actgcctctg ggaacttttt gacccatcaa
    20161 gccctacaag tttctactca gacggcaatg gtgatttggc agaattggcc gatgaatttg
    20221 ttgctatcaa taatgaggtt gttgactata ctcacgaact tggtttaacg gtttggacac
    20281 acaactgtcg tggtaattat gaaatccgtt ctgctgctga aggaacttac gaagacatcg
    20341 ctaagaaatt cttggcagag caacactatg accgcttctt ccttgaatgg gatagcgata
    20401 cagctggtga tatcaaagct ctggaagccc ttaaagacag taaagctgaa gttgtatttg
    20461 ggctattgtc ttcttaaacg actgacctag atgacgaaga acgtgttctc gatttgcttg
    20521 aaaaagcgag tcaaatcctt ccaaaaaaac gtctcttccc ctttcaccaa tgtggtttcg
    20581 cctcatgtga ctcaggtaat gagctggcaa cacctcaaca atgggctaaa atcaaacaag
    20641 gtcaagaaat cgctaagaaa ttctttggct aatcgatatt tctattcgct cctctctaaa
    20701 acgaaaagcc ttcactcttg tgagggcttt ttatgttagc atcaagcatc tataaaagtt
    20761 tgcaaatcct taagagctct ttctgcgatt ttttcataac gctctttctt gtcacgaata
    20821 cgtgggcctt ctaattcttt gataatacca aagttaacat tcattggttg aaaatgtttg
    20881 ctttcagcat gtgtcacata atatggaagg ctaccgattg ctgttgtatg agggaaaata
    20941 acttcatctt cacccttaaa gagacgggct gcattgattc cagcaaccaa acctgaggca
    21001 gctgattcaa cataaccttc aacaccagtc atttgtccag caaagaacag attagggttt
    21061 gattttgatt ggaaggtctg tttaagcaag tttggcgaat ccatgtaaga gttacggtgc
    21121 attaccccat aacgaacaaa ttctgcattt tcaagacctg gaatcatttg gaagacacgt
    21181 ttttgctctc cccatttgag gtgggtttgg aaaccaacga tattgtagag gctaccagcc
    21241 gcattgtcct gacgaagctg aacaaccgca taaggtgtct tgaagtcacc atcacgtgga
    21301 cccatataat cttcaggata ctccaaacca actggtttca taggaccgta gagcattgtt
    21361 ttaataccac gtttagccat aacctcgata ggcatacacc cttcaaaata cttttctttt
    21421 tcaaaagaat tcaaaggagc ttcttcagct gtagtcaagg cctcatagaa ggccatgaac
    21481 tcttccttgg tcattggaca gtttagataa gctgcttcac ccttatcata gcgtgactta
    21541 aggtaaacct tgttcatgtc gatagttgct ttatcaacga ttggtgcagc ggcatcatag
    21601 aaatagaacc cgtctccacc gttaagctca tgaatctttt cagctaaagc atcagaagtt
    21661 aggggacctg aagcaataac tgtaatagca tcatcaggaa tttctgtgat ttctttacgg
    21721 ataacttcaa ttaagggatg actttcaatt tcagctgtca ctgcttctgc atagccttca
    21781 cggtccaccg ccatggcacc acctgctggc acacggtgag cttctccatt acgcataatg
    21841 atagagtcca aacgacgcat ttcttctttt agaagcccta cagcattggt caagctatct
    21901 ccacggaaag agttagagca aaccaattct gcaaaatttg ttgtcttatg ctgtggtgtt
    21961 gctttgaccc cacgcatttc ataaagtttt actggaatac cacgtttggc aatctgataa
    22021 gccgcctcgg atccggccaa accagctcca atcacgttaa tataatctgc ttttgattga
    22081 gacatgacac taatacctct tcggaaacaa gatgaaatcc tgctcccaca aatctttctt
    22141 catttttact cttagtagta tagcaaaaaa ctcctcatct ggcgactagg agtcatctgt
    22201 atttaaaagg ggtaaaatga tagtcacttt agcaccaccc gtgccattgt catttgcaag
    22261 agaaagacta ccatagtgta aacgaataat atcattggca atagtcagac caaggccact
    22321 atgattgcga ctctgtctgc ttttatcctc ttgataaaat agctgagtag cgttttcaag
    22381 agatgcaagg gaaaatccag gaccagaatc aaggcatata aacttgaatt catcttcttc
    22441 taccctagcg gtcaggagca actgactgcc actgggtgta tgctctacgg catttgaaac
    22501 aatattcata atagctcgat tcaacaagga cttatcccaa ttgcctatgc tttctttcgc
    22561 aatttccttc ttgtcaaata ccacattgat ttgtttcgtt tgagctaatg acaaggtttg
    22621 atcgtaaatg tcttcaacaa attccttaac tggaacttct tcaagcgtca gggtcttctt
    22681 caaactcatt ttgttgagtt ctgacaactc ttttacataa gcatcaacct gtgcaatacc
    22741 tttttgaaaa tgctctaaca agtccgtttg attttcatcc aaggacgtca tagctaagag
    22801 ttccgcattt ccacgagcaa ctgttagggg cgtctttaag tcatgtgtca gggcagaaat
    22861 ctgattttgt ttatcttgct ctgccttcca attttccatc aaagactcac gaagtgctat
    22921 acgcatatga tccaaaccac ttaaaacctg attaaattcc ttaattgtag actgagaagt
    22981 ttgaaaatcc aaatcttgtt gggaaatttt ttcagtaacc cttaatatag gtttaagttg
    23041 ctgactcaat ttatttgcat aataaaaagt taaaataata aatatgatta agatagatac
    23101 aaacattgaa ccaatcatca taagatcagc attgggaaaa tgctggttca tccactcatt
    23161 acggtaccga ggtgatagtt gataattgac aatgactatg ccatctgatc gttcaaaaga
    23221 ctgaaaa
//
