LOCUS       c00006_JACSUK0..       23226 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JACSUK010000015.1 Streptococcus thermophilus strain 13500
            202-13500-15, whole genome shotgun sequence.
ACCESSION   JACSUK010000015
VERSION     JACSUK010000015
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 00:46:16
            Original ID  :: JACSUK010000015.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 108338
            Orig. end    :: 131564
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23226
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[118338:121564]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13226
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..23226
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..23226
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             complement(518..964)
                     /locus_tag="ctg6_132"
                     /transl_table=11
                     /translation="MKSAVYTKAGQVGLAEIDRPQIVAADDAIIKIVRTCVCGSDLWSY
                     RNPEMEEGHRNSGHEAIGIVEEVGEQVTTVKPGDFVIAPFTHGCGQCDACRAGFLTALV
                     ITTQVITGLRACRLSISVSTLPTGPLSKFLGNPQIIAKACSSHF"
     CDS             complement(1061..2155)
                     /locus_tag="ctg6_133"
                     /transl_table=11
                     /translation="MSKRAVLMMTFGSPEEITYEGVAEFFTNIRRGVRPEPHKIQTLHD
                     NYLRIGGTPLQRITREEVDLVASALGEQVSVYFANKFSRPFITDVITQMENDGIEECLC
                     LILEPHYSYYSVMGYEKFLESEHIRFQIIKDWYREPSLLHYWADEIRKILDQIGDDSYK
                     VIFSAHSVPVLALDFGDPYIDQIYDNSRLIAEDLGLREEQYTNTWQSESDIGIPWIKPD
                     VLEYLRDEREHPDHYIFVPIVFISEHIEVLFDNDVECKELCQELGVAYHRPPMPNRDPR
                     LIKALLSAIQSHIDGDYSYYQPQLETFDKLETPSSTGQILDEEKDIQMPDFVKKLIAKK
                     GLENVKMPYLFKKMLEKKYGKKYD"
     CDS             complement(2267..3163)
                     /locus_tag="ctg6_134"
                     /transl_table=11
                     /translation="MSSKYAVWLAFFLNLSFAIVEFIAGGIFVSSAVLADSVHDLGDAL
                     AIGLSAFLETISNREEDSRYTLGYKRFSLLGALVTAVILMTGSGMVILENVSKLFHPQP
                     VNDEGLLWLGIIAISVNLLASLVIRKGQTKNESILSLHFLEDTLGWLAVILMAIVLRFT
                     DWYILDPLLSLAISFFILSKAIPRFWSTLKIFLDVVPEGVDIKQVKNDLEQLDNVASIN
                     QLNLWTMDGLEKNAIVHVCLEHVKHIEVCKESIRDLLKESGFQNVTIEVDEDLATHQAH
                     KRNIEELEAESEQQHHH"
     CDS             3261..3836
                     /locus_tag="ctg6_135"
                     /transl_table=11
                     /translation="VYVTEQFVYSVHMTAQDRRITKTRKAIYQAFLYLLNQKDYEAITV
                     QEIIDLADVGRSTFYSHYESKELLLDELCQKLFHHLFERTQYLSPQDYLAHIFQHFKKN
                     QDHVTSLLLSKNDYFIRQLRKELEHDVYPMVADELIQSHPNIPHSYLKHLVVTNFIETL
                     TWWLKKGKSYSEQEVVQFYLEILNVASN"
     CDS             3875..4060
                     /locus_tag="ctg6_136"
                     /transl_table=11
                     /translation="MLLLILLGIFTAFLSLAFALLHLMASLSELRKHKNTGSIISVVGK
                     TTVGIIELFECRQKVP"
     CDS             4104..4268
                     /locus_tag="ctg6_137"
                     /transl_table=11
                     /translation="MRLIKNNTELIGIKDQNIKISLVFETDTHIEIQAKLDYPCSIMSS
                     LPRKKDDQI"
     CDS             4255..5358
                     /gene_functions="other (smcogs) SMCOG1206:transposase
                     (Score: 365.4; E-value: 6.1e-111)"
                     /gene_kind="other"
                     /locus_tag="ctg6_138"
                     /transl_table=11
                     /translation="MIKYDFQKNSKISLLEQAGTPTLLRLKKRRFQCKSCRSVTVAETS
                     IVEKNCQISNLVRQKVTQLLTEKVSLTDIARRLRVSTSTVYRKLDQFTFKEHYDKLPAV
                     MSWDEFGFKKGELAFVAQNYEINEPITILDNRHQTTIRNYFLKYPLKVRQQVQFITMDM
                     SGAYIPLARKLFPNAKIVLDRFHIIQHLGRAFLKTRIAIMNQFDKKSLPYRALKNHWRL
                     FQKDSRKLSLNSFYSKTFRQTLAPHEVVAKTLVFSKELTDYYTLYQLLLFHFQEKRVDE
                     FFELIEENRSKVNHYFQTVFRTFLRQKQYIKNALETDYSNAKLEATNKLIKDIKRLGFG
                     FRNFINFKKRVFITLNIHKKKDLSGPL"
     CDS             complement(5417..6136)
                     /locus_tag="ctg6_139"
                     /transl_table=11
                     /translation="MSEAIKLFQYNTLGALMAGLYGGTLTVGELLEHGDLGLGTLDSID
                     GELIVLDGKAYQAKGSEGKVEVVEVSPDEKVPYAAVVPHQAEVIFRQRYEMTDKELEDR
                     IESYYDGVNLFRSIKIKGHFKHMHVRMIPKSNADIKFADVATRQPEYEVDDISGTIVGI
                     WTPEMFHGVSVAGYHLHFISDDLTFGGHVMDFVIENGIIEVGPVDQLDQRFPVQDRQYL
                     FAKFNVDEMRKDITKAE"
     CDS             complement(6152..7828)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 504;
                     E-value: 9.2e-153)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_140"
                     /transl_table=11
                     /translation="MSEEKQLYGADLVVDSLINHDVEYVFGIPGAKIDRVFDTLEDKGP
                     ELIVARHEQNAAFMAQGVGRITGKPGVVLVTSGPGVSNLATGLVTATDEGDPVLAIGGQ
                     VKRADLLKRAHQSMNNVAMLEPITKYAAEVHDANTLSETVANAYRHAKSGKPGASFISI
                     PQDVTDAPVSVKAIKPMTDPKLGSASVSDINYLAQAIKNAVLPVFLLGNGASSEAVTYS
                     IRQILKHVKLPVVETFQGAGIVSRDLEEDTFFGRVGLFRNQPGDMLLKKSDLVIAIGYD
                     PIEYEARNWNAEISARIIVIDVEPAEVDTYFQPERELIGNVEASLNLLLPAIQGYKLPE
                     GSVEYLKGLKNNVVEDVKFDRQPDEGTVHPLDLIEVLQEQTDDDMTVTVDVGSHYIWMA
                     RYFKSYEPRHLLFSNGMQTLGVALPWAISAALVRPKTKVISVSGDGGFLFSAQELETAV
                     RLKLPIVHIIWNDGHYNMVEFQEEMKYGRSSGVDFGPVDFVKYAESFGAKGYRATSKAA
                     FASLLQEALAQAVDGPVLIDVPIDYKDNIKLGETILPDEFY"
     CDS             complement(8082..9254)
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 61.4; E-value: 1.2e-18)"
                     /gene_kind="transport"
                     /locus_tag="ctg6_141"
                     /transl_table=11
                     /translation="LKIKKYAALSIYFNRFSSLISEYGYTILINILLSRISVQLVMYFW
                     VVKCLAAIVTNRINISNSKLSRKYLLILLEITKAILLFLLGFGLNHIIVLLVVFIIEVV
                     NVLFSSLLYSCVPIIIDKDSLIKFNARYTSIGSVSYFLAPLFVGLFINKSHFLLFAVYA
                     LLLIVGATSLLFLPNISTLNLKEERKKQNLNITLFNILRSKKIALVLLSGVIVGSIGVV
                     YDTYEVVYLTKYLGISDSMYSFSLSFLAVSFLVMSFLLSFVKQISSHMKAFALGLSFYV
                     LYLLLFSTSSNIYTVLMSYVFLAIGQTMMGIIETNYFQLSLNMKELQKLYIYSETLHSV
                     FSGIAVLVIGSFAFLSSHLVLVFRSLAVFALFILLCYCVFVNLKKLSIDK"
     CDS             complement(9261..10004)
                     /locus_tag="ctg6_142"
                     /transl_table=11
                     /translation="MKILSIIYDGGSRIPGARFAPTKYYQEAMLYDRKDSDIITINLGN
                     QDLFSIDLESLSRTIAESKVQIALGGDHSVTYLLAKATVREGAYLIVLDAHLDYFKDFE
                     SVVKNWNFLSFLTDIFEKIIIIGERNFEFPSSFDNKIIILSMEEYWLNKSRVLKKLDSY
                     IDESKDIYLSIDIDVLDPSVFDSVSYPIIGGFQMNDFLGIISKILCSDKVYFCDIVEYN
                     PMVGSDNAHIFYQMIQFVKSKLRRI"
     CDS             complement(10001..11098)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_143"
                     /sec_met_domain="PF04055 (E-value: 1.9e-21, bitscore: 70.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 6.2e-10, bitscore: 33.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.1e-11, bitscore:
                     37.6, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 5.6e-09, bitscore: 29.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYQFSLKKFSDSKSQVIKNVIDFLNNNEISLSKTNTKIVEFSTKI
                     PLKVIQIEVTNKCNLRCMHCYLPDYSKELDRKKISSIVYEAKQLGVMDVDFTGGEPLLL
                     QGLSEIIEEVLKEGMCTTIFTNAVYIPEDFKILIQRYDGIRLKVSLDGWNETIHDSIRG
                     RGTFKRTIKNIEYFRSLGVPVTVNVVLNNKNISGVKYFLELFDRLDVKYAFDRFLPFER
                     NNRLSISDEEFNNAILCIPNIQANCNNISESTFESFYCGAGNSYVFINSSGDVGFCPTL
                     SSTKFCGGNINEKTLNDIWINSKFFNHIRNVRCKYYNECPANYVCQGGCRSRAQFFGGS
                     IGSPDIQECKLAYNLTGIKPKSMSL"
     CDS             complement(11300..11449)
                     /locus_tag="ctg6_144"
                     /transl_table=11
                     /translation="MQVSDAIAQIELAEEEVVSSGLSIDIMEIKPSVATELIDGLKGHC
                     PPSV"
     CDS             complement(11509..12309)
                     /locus_tag="ctg6_145"
                     /transl_table=11
                     /translation="MRIIKFPEQISEDIIHYTFLDDIISYNCEKCRGSCCHVNNSLLLD
                     AKTASFLKRTYLKDFIVSDDSVSLLSCGKKCWFHSELGCTINDLGLNKPLTCELYPFHI
                     KKIQNFYIVSFTPCPTFQLNLGEGQRYKDIEDVVLRYIKTGVPVFSPSLHVSEERLKYE
                     IEYQNNFKNTLSEYYRTKTADGTTEFKEYEKWYIYYLDFRWGSIPLSYTSSQANQFWNL
                     YKRVCEDVYKKISYIRTDNIYFIIANQFNKTISKHFQLNFIDKE"
     CDS             complement(12369..13226)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_146"
                     /sec_met_domain="TIGR01716 (E-value: 5.6e-46, bitscore:
                     150.3, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYGKLFKKFRESRGLVLKDIAKLGVSVSHISRFERENTDLTIS
                     KFMSALNAINMPIDEFMYAANDFQRDEFNEILEKISLFVSARNVSGMEKLLISQVEKIE
                     KRETFYTLNTILIKIRLQDLSDKSYYDESDIQYLSDYLFSVEYWGCYELLLFANTVDVL
                     NHQTMMLLSREMCKRSEFYKDLPNYRRLHSTMLLNCYIISIERDEYIDALYFEKQLNHS
                     CFTETEIYEKLVFHYSKNLYELKKNRSNKAILEMKKCITAMKLANSENLAIKFENHLSG
                     VLKM"
     CDS             complement(13560..13889)
                     /locus_tag="ctg6_147"
                     /transl_table=11
                     /translation="MKEIKLTPLDKVDRNGFLASYLAERSKKAPEILQHYNNEIECIKL
                     SHKIKQLRENINLTQQELADRMGKSQASIGRIENGTTNPTYKTLEEIAAATNTRLVVDF
                     VPIKN"
     CDS             complement(14004..14249)
                     /locus_tag="ctg6_148"
                     /transl_table=11
                     /translation="MALKLVRKVDRKKDIFELRINTEGIFARSLFFRLEKANEEEDNVA
                     SPTYIITNSFKKKTNKTPSKELKKAIKRKSNYKNKR"
     CDS             14407..14775
                     /locus_tag="ctg6_149"
                     /transl_table=11
                     /translation="MKHKKMKQKRHKLAKERKNVSGEPGELIAKRYFMYLKRFQAVGFL
                     NPLQIRLIAETFAHIPTSYFFDENRNDWWNYYQMEVDYCEILNFQHKKKHLITIRCLCI
                     FYLSKLSIKIMLQAFKNL"
     CDS             complement(14710..15051)
                     /locus_tag="ctg6_150"
                     /transl_table=11
                     /translation="MDITNFIPSQRQAMLERFQQVEALGLGAVRIELKVANPVGIIYEC
                     YIMSGENYFSDQAVVSFRILYEKDLDRISLDVVDIPGRSSLSNYLQLLEIFEGLQHYLN
                     REFAKVKNT"
     CDS             complement(15457..17289)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190:GTP-binding protein LepA (Score: 550.4; E-value:
                     9.1e-167)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_151"
                     /transl_table=11
                     /translation="MPNIEELKQRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKDGETYIFHLIDTPGHVDFTYEVSRSLAA
                     CEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRTEIEDVIGL
                     DASEAVLASAKAGIGIEEILEQIVEKVPAPQGDVEAPLQALIFDSVYDAYRGVILQVRV
                     VNGMVKTGDKIQMMSNGKTFDVTEVGIFTPKAVGRDYLATGDVGYVAASIKTVADTRVG
                     DTVTLADNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPET
                     SQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSE
                     FPDPTRIDAIEEPYVKAQIMVPQEYVGAVMELAQRKRGDFETMEYIDDNRVNVIYQIPL
                     AEIVFDFFDKLKSSTRGYASFDYELSEYRRSQLVKMDILLNGDKVDALSFIVHREFAYE
                     RGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARTDIKALRKNVLAKCYGGDVSRKRKLL
                     EKQKAGKKRMKAIGSVEVPQEAFLSVLSMDEDEK"
     CDS             complement(17677..17823)
                     /locus_tag="ctg6_152"
                     /transl_table=11
                     /translation="MQTFAKDITLKRLSEPEDVAAAVSFLAGPDSNYITGQTIIVDGGM
                     QFH"
     CDS             complement(18099..18440)
                     /NRPS_PKS="Domain: PKS_KR (3-111). E-value: 4.2e-10. Score:
                     31.5. Matches aSDomain: nrpspksdomains_ctg6_153_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     107.7; E-value: 1.1e-32)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_153"
                     /transl_table=11
                     /translation="MSKVAIVTGAGQGIGFAISKRLVEDGVKVGVLDYDAETAEKAVAE
                     LSEDKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVAPTKSLDTITEEQFQHT
                     FNINIGGVI"
     aSDomain        complement(18108..18431)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg6_153_PKS_KR.1"
                     /evalue="4.20E-10"
                     /label="ctg6_153_PKS_KR.1"
                     /locus_tag="ctg6_153"
                     /protein_end="111"
                     /protein_start="3"
                     /score="31.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAIVTGAGQGIGFAISKRLVEDGVKVGVLDYDAETAEKAVAELSE
                     DKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVAPTKSLDTITEEQFQHTFNI
                     NIGG"
     aSModule        18108..18431
                     /domains="nrpspksdomains_ctg6_153_PKS_KR.1"
                     /incomplete
                     /locus_tags="ctg6_153"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(18357..18425)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg6_153_0001"
                     /evalue="1.20E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg6_153"
                     /protein_end="28"
                     /protein_start="5"
                     /score="11.6"
                     /tool="antismash"
                     /translation="IVTGAGQGIGFAISKRLVEDGVK"
     CDS             complement(18651..18944)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163:rhodanese domain-containing protein (Score: 60.2;
                     E-value: 2.8e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_154"
                     /transl_table=11
                     /translation="MDIAQIQSELAQDGLLIDVRTPEEYAEGHVKDALLIPHTQFFTAD
                     IPAKKDASIYLYCKMGSRAEFAAGVLKERGYTKVTTLGGLGDMEALGFKFEK"
     CDS             complement(18946..19374)
                     /locus_tag="ctg6_155"
                     /transl_table=11
                     /translation="MKVGNMQKTFFIIKPDAVKRHLIGQVLDRIERRGFVIERMEMLML
                     DEERLKEHYAQLADKPFFPSISEFMMSGPAVIGIMSGPGVIKSWRDMMGATNPGDAAPG
                     TIRGDFATAPDGDMIPNIVHGSDSEESAAREIKIWFGE"
     CDS             19685..20476
                     /locus_tag="ctg6_156"
                     /transl_table=11
                     /translation="VADQKANGIDILTDGKFGRSMWHLDFVWGLKGIERYIAEHGYTFK
                     DHDGGQYETRKDIGIRITEPLSGKNHHYLDIYKLVKAEAGDEDTKQTIWGPAHAYTELA
                     IFDRLAVPGQVYETNEELKKGLINAYKEFLDEYKAVGGKIVQFDDCLWELFDPSSPTSF
                     YSDGNGDLAELADEFVAINNEVVDYTHELGLTVWTHNCRGNYEIRSAAEGTYEDIAKKF
                     LAEQHYDRFFLEWDSDTAGDIKALEALKDSKAEVVFGLLSS"
     CDS             complement(20741..22084)
                     /locus_tag="ctg6_157"
                     /transl_table=11
                     /translation="MSQSKADYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQ
                     HKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEAHRVPAGGAMAVDREG
                     YAEAVTAEIESHPLIEVIRKEITEIPDDAITVIASGPLTSDALAEKIHELNGGDGFYFY
                     DAAAPIVDKATIDMNKVYLKSRYDKGEAAYLNCPMTKEEFMAFYEALTTAEEAPLNSFE
                     KEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPEDYMGPRDGDFKTPYAVVQLRQDN
                     AAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLKQTFQS
                     KSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKGEDEVIFPHTTAIGSLPYYVTH
                     AESKHFQPMNVNFGIIKELEGPRIRDKKERYEKIAERALKDLQTFIDA"
ORIGIN
        1 ttataacttg tcgtaaagac tcggcctgga ttgatgtcgc catcaagaac agcttttaac
       61 aaaacttgtt tatcataggt tgtgacagag gctacccctc ccgccactaa aatattttgg
      121 gcaaaggtcg aaccaaggga acggttatta taatgaggca caccgacaaa tcccatacga
      181 ccaccgttat ggaggacacc aagagcttgt tctactgctg cttcagtacc gacacattcg
      241 agagctgcat ctgctcctcc cccgaggatt tcacggactt tgtcaatgcc tttttcgcca
      301 cgctcagcta caaccgcagt cgcacctgac tccaaagcca tcttttgacg atcttcgtga
      361 cggctcataa ggacaatttg agaagctcca cgcatcttag atgcaatgac agcacattga
      421 ccaacagccc catctccgat aacgacaacc ttatcaccct tttgtacatt agccacacgc
      481 gcagcatggt aacccgtcgg cataacatca gcaagtgtca aaagtgactt gagcatgcct
      541 tcgctataat ctgagggttg cccaagaatt ttgacaaggg cccagttggc aaagtggaaa
      601 cggatatact cagcctgcac gccctcagac cagttattac ctgagtggtt atcacaagag
      661 ccgtcaaaaa accagctcga caagcatcac actgaccaca cccatgtgtg aaaggtgcaa
      721 tgacaaagtc tcctggtttt accgtagtaa cttgctcacc aacttcttcg acaattccga
      781 tagcctcatg accactattt ctatgtccct cttccatttc cggattacgg taactccaaa
      841 ggtcagatcc acaaacgcaa gtacgtacta tcttgataat ggcatcatct gctgccacga
      901 tttgcgggcg atcaatttct gccagcccca cttgtccagc tttggtataa actgctgatt
      961 tcatatatct acctctattt ctttagttat agttagtata cacttttagg caagctttag
     1021 ctcacatcat gccctccaaa ttactttcaa acaatagcaa ctaatcatat ttttttccat
     1081 acttcttttc aagcattttc ttaaatagat atggcatctt gacattttct agaccttttt
     1141 tagcaatcaa tttcttgacg aaatcgggca tttgaatatc cttttcctca tccaaaatct
     1201 gacctgtgct agaaggagtt tccagcttat caaaggtctc aagctgaggt tgatagtaac
     1261 tatagtcacc gtctatatga gactgaatag ccgaaagaag ggccttgatt aaacgaggat
     1321 cgcgatttgg catgggaggt ctgtgatagg ctacacctag ctcttggcaa agttccttac
     1381 attccacatc attatcaaaa agaacctcaa tatgctcact aataaagaca atagggacaa
     1441 aaatatagtg gtctgggtgt tcacgctcat ctcgtagata ttctaagaca tcaggcttaa
     1501 tccaaggaat acctatatca ctctcactct gccaagtatt agtgtactgc tcttctctaa
     1561 gtcctaaatc ctccgcaatt aagcgactat tatcataaat ctggtcgata taagggtcac
     1621 caaaatctag tgccaaaact gggacactgt gagctgaaaa aatcacctta taactgtcgt
     1681 ctccaatctg atctaaaatc ttccggattt catcagccca atagtgaaga agagaaggtt
     1741 cgcggtacca gtccttgata atttggaacc taatatgctc actttctaaa aatttctcat
     1801 atcccatgac agaatagtaa gaataatggg gctctaaaat caagcacaaa cattcttcaa
     1861 ttccgtcatt ctccatctgt gtaatcacat ctgtaatgaa aggtcgtgaa aatttattgg
     1921 caaagtaaac cgacacttgt tctccaagag cagaagcaac caaatccacc tcttctctgg
     1981 ttatcctttg gagtggagtt ccaccaattc ggaggtaatt gtcatgtaaa gtctgaattt
     2041 tatgtggttc aggacgaaca ccacgccgta tattcgtgaa aaactccgct actccttcat
     2101 aggtaatctc ttctggtgac ccaaaggtca tcatcaacac agctctctta ctcataatta
     2161 atccttgttc tacatttgct ctattttatc atgaaaagga tcactttagg gaacttggta
     2221 tcaaaataac tcttaaaggt agactctaag agtttaaaaa caaaccttaa tgatggtgtt
     2281 gctgctcact ttctgcttct agctcttcga tatttcgctt gtgagcttgg tgggttgcca
     2341 agtcttcatc aacttcgatg gtgacatttt gaaagccact ctctttgagc aagtctcgga
     2401 tagactcttt acagacctcg atatgtttga catgctccag acaaacatgg acaatagcat
     2461 ttttctccaa gccgtccatg gtccaaagat taagctgatt gatactagca acattatcca
     2521 actgctctaa gtcattctta acttgcttga tatctacccc ttctggcaca acatccagga
     2581 aaatcttgag cgtgctccaa aaacgtggaa tggctttgga cagaataaag aaggaaatag
     2641 caagagacaa gaggggatct aggatatacc agtccgtaaa tcggaggaca atggccatca
     2701 ggatgacagc caaccaacct aaggtatctt ccaaaaaatg caggctgaga atagactcat
     2761 tcttggtctg acccttacga atgaccagac tcgccagcag attgacactg atagcaataa
     2821 ttcccaacca aagaagccct tcgtcattga cgggttgtgg gtggaaaagc ttgcttacat
     2881 tttctaaaat caccatacca gaccctgtca tcagaatgac tgccgttacc aaagccccta
     2941 ataagctaaa acgcttgtag cctagggtat agcgactatc ttcttcacga ttggagattg
     3001 tttctagaaa ggccgagagg ccaatggcta gagcatcccc caagtcatgg acagagtcag
     3061 cgagaacagc actggaaaca aagattcccc ctgcaataaa ctcaacaatg gcaaagctta
     3121 gattcaagaa aaaagccaac cagactgcat attttgaact cattttttac cttcctttgg
     3181 tataatagat tcacgaacat catattcaat atctattatc caatactacc aacagaaagg
     3241 ataggggcaa accgttcgct gtgtacgtta ctgaacagtt tgtttatagt gtccatatga
     3301 ctgcacaaga tcgtcgcatt accaagacta gaaaagccat ctatcaagct ttcttgtact
     3361 tacttaacca aaaagattat gaggccatca ccgttcagga gattattgac ttggctgatg
     3421 tggggcgttc gaccttttac agccattatg agagcaaaga gttactactg gatgagctct
     3481 gccaaaagct ctttcaccat ttgtttgagc gtactcaata cctctctcca caagactacc
     3541 tggcccatat ctttcaacat ttcaagaaaa atcaagacca tgtaaccagt ctcttgcttt
     3601 caaaaaacga ttattttatc cggcagctgc gaaaagaact ggaacatgac gtctatccaa
     3661 tggtagctga tgaactgatt caatcacacc ccaacattcc tcactcatat ctcaagcacc
     3721 tggttgtaac caacttcatt gaaaccctga cctggtggtt gaaaaaaggc aagtcctaca
     3781 gcgagcagga agtagtccag ttttatttgg agattttaaa cgtcgcttct aactaaggtg
     3841 cgactttaca tcatgtatca tagaaaggaa aactatgctc ctcctcattc ttcttggtat
     3901 tttcacagct ttcttatccc ttgcttttgc tcttcttcat ttaatggcca gtctttcaga
     3961 attaagaaag cacaagaata ctggctctat aatttctgta gtgggtaaaa ctactgtagg
     4021 gattatagag ctttttgagt gcagacaaaa agtcccataa gaactataat gaaaagcaac
     4081 caaaccatca ttaggaagaa cttatgagac ttattaagaa taacacagaa ttaatcggaa
     4141 tcaaagacca aaatatcaag atttcacttg tttttgaaac tgatactcat atcgagattc
     4201 aagcaaaact tgattaccct tgctccatca tgtcctcact gccaaggaaa aaagatgatc
     4261 aaatatgact ttcaaaaaaa ctctaaaatc tctcttctcg agcaagcggg aacgccaact
     4321 ctactacgtc tgaaaaaacg tcgtttccag tgtaaaagtt gtagaagtgt cacggtagct
     4381 gagacatcta tcgttgagaa aaactgccaa atctccaatc tagtccgaca aaaagttaca
     4441 caactcctaa ctgagaaagt gtcactaact gatattgcaa gaagacttcg cgtgtcgaca
     4501 tccactgtct atcgtaagct tgatcagttt actttcaagg aacattatga caaactccct
     4561 gctgttatgt cctgggatga gtttgggttc aagaaagggg aattggcttt tgtggcgcag
     4621 aattatgaga taaacgaacc cataaccatc cttgataatc gccaccaaac tactatacga
     4681 aactactttt tgaagtatcc attgaaagtc cgacaacagg tacagtttat cacgatggat
     4741 atgtctggag cttatattcc actggctcgc aagctctttc caaacgcaaa aatcgttctt
     4801 gatcgtttcc acatcatcca gcaccttgga cgtgcctttt taaagacaag aattgcaatt
     4861 atgaaccagt ttgataagaa gtcactaccc tatcgagccc tgaaaaatca ctggcgactc
     4921 ttccaaaagg acagccgtaa actatctctc aactcttttt attcaaagac tttccgccaa
     4981 actttagcac cacatgaagt tgttgcgaag acactagtct tttcaaaaga gcttactgac
     5041 tactatacac tttatcagct tttgcttttt cactttcagg agaagagagt agatgagttc
     5101 tttgaactga tagaggaaaa taggagtaag gtcaatcatt attttcaaac tgtctttagg
     5161 acttttctta gacagaagca atacatcaaa aacgcactag aaacggacta ttcaaacgca
     5221 aaacttgaag cgactaataa gttgatcaaa gacatcaaac gcttgggctt cggttttaga
     5281 aactttatca actttaagaa gcgtgtcttc atcacactga acatacataa aaaaaaggac
     5341 ctatccggtc ctctctagat gttagctttt cgttacccac tacagttgac aaagagacag
     5401 tatcttattt atatgcttat tcagccttag taatatcttt acgcatttca tcaacattga
     5461 atttagcaaa gagatattga cggtcttgaa ctgggaagcg ttgatcgagt tggtcaactg
     5521 gtccaacttc aataatacca ttctcgataa caaaatccat aacgtgacca ccgaatgtca
     5581 agtcatctga aataaaatgg agatggtaac cagcaacact cacaccgtgg aacatttcag
     5641 gtgtccagat accaacgatt gtacctgaaa tatcatctac ctcatactca ggttggcgag
     5701 tggcaacatc agcaaactta atgtccgcat ttgattttgg aatcatgcgc acgtgcatgt
     5761 gtttaaaatg acctttgatt ttgattgaac ggaaaagatt gaccccatca tagtatgatt
     5821 caatacgatc ctcaagttct ttatcagtca tttcataacg ttgacggaag ataacttcag
     5881 cttggtgagg tacgactgct gcatagggaa ctttttcatc aggagaaact tctaccactt
     5941 cgactttacc ttcagagcct ttagcttgat aggctttacc gtcaagaaca atcaactcac
     6001 catcgataga atctaatgtt ccgagaccca agtctccatg ctctaacaac tctccaacgg
     6061 ttaaagtacc tccataaagc ccagccatca aggctcccaa agtattatat tgaaataatt
     6121 ttatggcttc agacatgtct acaccctctt tttagtaaaa ttcatctggc aaaatagttt
     6181 cgccgagttt aatgttatct ttatagtcaa ttggaacatc aataaggact ggtccatcta
     6241 cagcttgagc caaggcttct tggagcaagc tagcaaacgc tgctttactt gttgcacgat
     6301 aacctttggc tccaaagctc tcagcatatt ttacaaaatc tacaggacca aagtcaaccc
     6361 cagatgaacg accgtacttc atttcttcct ggaattccac catattgtaa tgaccatcgt
     6421 tccagataat atggacaatt ggcaatttca aacgaactgc tgtttccaat tcttgtgctg
     6481 agaagaggaa accaccatca ccagaaacag aaatcacttt tgtcttagga cgaaccaaag
     6541 ctgcagagat agcccatgga agagcaacac ctagcgtttg catcccattt gagaaaagca
     6601 aatgacgtgg ttcatacgat ttgaaataac gtgccatcca aatatagtga ctaccaacat
     6661 caaccgtaac agtcatatca tcatctgttt gttcttgcaa aacttcgatt aaatctagcg
     6721 gatgcaccgt accttcatca ggctgacggt caaacttaac atcctcaaca acattgtttt
     6781 tcaaaccttt aagatattca accgaacctt caggcaattt ataaccttga atagcgggca
     6841 aaagcaagtt taagctcgct tctacattac caatcaattc acgttccggt tggaagtaag
     6901 tgtccacctc ggccggctca acatcaataa cgatgatacg tgctgaaatt tcagcattcc
     6961 agttacgtgc ttcatattcg attgggtcat aaccaatggc aataactaag tcggattttt
     7021 taagcaacat gtctccgggt tggttacgga aaagacctac acgaccaaag aaagtatctt
     7081 cttcaaggtc acgtgacacg ataccggcac cttggaaagt ttcaacaact ggcaatttaa
     7141 catgcttcaa aatttggcga atagagtaag ttacggcttc tgatgaggca ccattcccca
     7201 aaagaaagac tggcaacact gcatttttaa tggcttgtgc gagatagtta atatcagaaa
     7261 cagatgctga accaagtttt ggatctgtca taggcttaat agccttaaca ctgaccggag
     7321 catccgtcac gtcttgagga attgaaatga agcttgcacc tggtttccct gacttagcgt
     7381 gacgataggc attagcaacc gtttcagaaa gggtgttagc atcatgtact tcagcagcat
     7441 atttggtaat tggctcaagc atagcaacgt tattcattga ttggtgggca cgtttcaaga
     7501 gatctgcacg cttaacctga ccaccaatag caagaacagg gtctccttca tccgtcgctg
     7561 ttaccaaacc agtagccaaa ttggagacac ctggaccaga tgttaccaat actacacctg
     7621 gtttcccagt aatacgtcca acaccttgag ccataaaagc agcattttgc tcatgacggg
     7681 caacaatcaa ttcaggtccc ttatcttcca aggtatcaaa aaccctatcg atttttgcgc
     7741 ctggaatccc aaagacatac tcaacatcat ggttgatcaa actatcaacc actaaatctg
     7801 caccatacaa ttgcttttct tctgacatga acacagtcct tctagcccta aaatggtaga
     7861 gccaactttc ctttcaagta taagtcacaa agtgtcaaag tctgctcgtt ttttcacaaa
     7921 ctttcatcaa ttcacaattc tgttatcatt atagcacagt tttcagacaa tcttgtgaaa
     7981 aaaggcagac taggtgacta aaaaaagaca aacactcaaa atagcgtttg tctactttat
     8041 aaattaacta tctcatttgc ttgttttctg atttataaat attacttatc aatgcttagt
     8101 tttttgaggt ttacaaacac acaataacac agaagaataa acagagcaaa aacagcaaga
     8161 cttctgaaaa ctaaaacaag atgactactt aaaaaggcaa aacttcctat tactaaaaca
     8221 gcaatgcctg aaaatacaga atgtaaggtc tccgagtaaa tatatagttt ctgtaattct
     8281 ttcatgttaa gtgacaactg aaaataattg gtttcgatta tccccatcat tgtctgacct
     8341 atcgctagaa aaacataact cattagtact gtataaatgt tcgaagatgt actaaataaa
     8401 agtagatata gaacataaaa tgaaagacct aaggcgaaag ctttcatatg agaacttatt
     8461 tgtttcacga agctaagaag gaagctcatt actaagaatg aaactgctaa aaatgataag
     8521 gaaaaggaat acatagaatc actaataccg agatactttg ttaaataaac aacttcataa
     8581 gtatcataaa caactccaat tgatcccaca ataactccag ataatagaac taatgcaatt
     8641 tttttggatc tcagaatgtt aaataatgta atgtttaaat tttgtttttt tctttcttct
     8701 ttcaaattta aagtcgaaat atttggtaaa aataaaagac tagtagctcc cactatcaaa
     8761 agaagagcat aaactgcaaa caataaaaag tgacttttat taataaataa accaacaaac
     8821 aacggtgcta aaaaataaga tactgaacca atgcttgtat acctagcgtt aaacttaatc
     8881 aatgaatcct tgtctataat aattggtaca caactatata ataaactgga aaacaataca
     8941 ttgacaacct caattatgaa tacaactaat aggacaatta tatggtttaa tccaaaacct
     9001 agtaagaaaa gtaagattgc ctttgtaatt tctaacagaa taagcaggta ttttctgctc
     9061 agtttactat ttgagatatt aatcctattt gtaactattg cagctaaaca ctttaccacc
     9121 caaaaataca taactaattg cacagaaatt ctagacaata gaatgttgat caagatagta
     9181 taaccatact ctgagattaa cgatgagaaa cgattaaaat aaatactcaa tgctgcatat
     9241 ttttttattt tcaatatttc ctatatcctc cttaattttg atttaacaaa ttgaatcatt
     9301 tggtaaaaaa tgtgagcatt atcacttcca accatcggat tgtactcaac tatatcacaa
     9361 aaatatacct tatcagaaca taaaattttg gaaattattc caagaaaatc gttcatttga
     9421 aatcctccaa taataggata tgatactgaa tcaaaaacag atggatccaa aacatcaatg
     9481 tctattgata agtaaatatc ttttgactca tcaatataac tatctaactt tttcaaaact
     9541 ctactcttat ttaaccaata ctcctccatt gagaggatga ttattttatt atcaaatgaa
     9601 ctaggaaact caaaattcct ttccccaatg ataattattt tttcaaaaat atcggttaaa
     9661 aaacttaaaa aattccaatt ttttacaaca ctttcaaagt ctttgaagta atctaaatga
     9721 gcatctaaaa caattaaata tgctccctct cgaacagtgg cctttgctaa tagataagta
     9781 actgaatgat ctcctcctaa agcaatctga actttagatt cagcaatagt tcgacttaga
     9841 ctttctaaat caatagaaaa taaatcttga ttacctaaat taattgtaat tatatcagaa
     9901 tctttcctat catataacat cgcttcttga taatattttg tgggtgcaaa tctcgctcct
     9961 ggaattctac ttccaccatc ataaataata gataatattt tcataaactc attgactttg
    10021 gcttaatccc agttaaatta tatgctaact tgcactcctg tatatcggga ctcccaatag
    10081 aacctccgaa aaactgagct cgacttctac acccaccttg acaaacataa tttgcagggc
    10141 attcattata atacttacat cgtacatttc gaatatgatt gaagaacttc gaattaatcc
    10201 aaatatcatt taaagtcttt tcattaatgt tacctccaca aaatttagtg gaggataatg
    10261 tcggacaaaa tccaacatca cctgacgaat ttataaacac ataagaattg ccagcaccac
    10321 aataaaatga ttcaaatgtg gattcggata tattattaca atttgcttga atattgggaa
    10381 tacacaaaat agcattattg aattcttcat cactaattga tagtcgatta ttcctttcaa
    10441 aaggtaaaaa cctatcaaaa gcatatttca catctaatcg atcaaacaac tccaaaaaat
    10501 acttcactcc actaatattc ttgttattca aaacaacatt aacagtaaca ggtactccta
    10561 aactcctaaa atattcaata ttcttaattg ttctcttaaa tgtacctctt cctctaattg
    10621 aatcatgtat tgtttcattc caaccatcta aactaacttt tagtcttata ccatcatatc
    10681 tttgaatcaa tattttaaaa tcttcaggaa tatatacagc atttgtaaaa attgttgtac
    10741 acattccctc ttttaatact tcctcgataa tttcacttaa tccctgtaat aataatggtt
    10801 cgcctccagt gaaatcaaca tccattactc ctagctgctt agcttcatat actatacttg
    10861 aaattttctt tctatcgagc tcctttgaat aatcaggtaa ataacaatgc atacatctta
    10921 ggttacattt gttcgtgacc tcaatctgta tcacttttaa tggtattttc gttgaaaatt
    10981 caacaatttt agtgttggtc ttagagagtg atatttcatt gttatttaga aaatctataa
    11041 cattttttat tacctgactc tttgaatcag aaaacttttt caatgaaaat tggtacataa
    11101 attttaaagc taaaaatgta gctaaattta atgaaaatag tttattattc ctattattcc
    11161 tgagtattcc ttgcttattg taccaattaa aaaaatcgag taaacattgc tcgtcatatt
    11221 aattccctgc aatcttccaa aaatattaat ataaaaacca aaggattaga aatagactct
    11281 aatcctacaa tcagttctat tagacagacg gtgggcaatg acctttgagt ccatcaatca
    11341 actctgtagc aacagaaggt ttaatttcca taatgtcaat agatagaccg ctagaaacaa
    11401 cttcttcttc tgctaattca atttgtgcaa tagcatcact aacttgcatc gtaatatcct
    11461 ccattattta tttaagaatc aataagtacc cataacaaat catagaaatc attctttatc
    11521 tataaaattt agctgaaaat gctttgaaat tgtcttatta aactgatttg caataataaa
    11581 gtatatgtta tctgttcgta tatatgatat ttttttataa acatcttcac aaactctctt
    11641 gtaaagattc caaaattgat ttgcttgtga acttgtataa gataagggta tacttcccca
    11701 tctaaaatct aaataatata tataccattt ttcatattct ttaaactctg tagtgccatc
    11761 ggcagtcttt gttcgataat actctgataa agtgttttta aaattgtttt gatactcaat
    11821 ctcatatttc agcctttcct ctgaaacatg caaagacgga ctaaaaactg gcaccccagt
    11881 tttaatatat cgtaaaacta catcctctat atccttgtac ctctgcccct caccaaggtt
    11941 cagttgaaat gtcggacaag gagtaaaaga aacaatatag aagttctgaa ttttcttaat
    12001 atgaaaagga tataattcac aagttaatgg cttgttcaag cctaaatcat ttatcgtaca
    12061 acccaattca gaatgaaacc agcacttttt accacaactc aacaatgaaa cactatcatc
    12121 actaacaata aaatctttaa gatacgtgcg ttttagaaaa cttgctgtct ttgcatcaag
    12181 taataaagaa ttattcacat gacaacaaga tcctctacac ttttcacaat tataagagat
    12241 aatatcatct agaaacgtat aatgaatgat atcttctgaa atctgttcag gaaatttaat
    12301 aattctcata tcaataatat atcatttaat tttgacactg ataatttata ccatatacac
    12361 aaatccaact acatttttaa cactccagat aaatgatttt caaattttat agctaaattc
    12421 tcactattag ccagcttcat tgcagtaata cacttcttca tttctagaat agctttattg
    12481 ctcctattct tctttaattc atataaattt tttgaataat gaaacactaa tttctcgtaa
    12541 atctcagttt ccgtaaaaca actatgattt aactgttttt caaaatacaa cgcatcaata
    12601 tactcatctc tttcaatact tatgatataa caatttaata gcattgttga gtgtaacctt
    12661 cggtagtttg gtaaatcctt gtaaaattct gaacgtttac acatttctct tgataaaagc
    12721 atcattgttt gatgattcaa tacatctaca gtattcgcaa ataacagtag ttcgtaacaa
    12781 ccccaatatt ctacagagaa taggtagtct gataaatatt ggatatcaga ttcatcatag
    12841 taacttttgt ctgataagtc ctgtaaacga atttttatta aaatagtatt tagagtataa
    12901 aaagtctcac gcttttcgat tttttctact tgagagatta ataacttttc catacctgac
    12961 acgttccttg ctgaaacaaa taaactaatc ttttctaaga tttcattaaa ctcatctctc
    13021 tgaaagtcgt ttgctgcata cataaactca tcaataggca tatttatcgc atttaaagct
    13081 gacataaact tactaattgt caaatctgta ttttcacgtt caaagcggga aatatgagat
    13141 actgatacgc ctaactttgc gatatctttt aagactaatc ccctagactc tctaaatttc
    13201 ttaaataatt ttccataatc tttcataaaa agcacctctt ttgcatatac gagaatttcc
    13261 cagataaact taaaagtatt atatcatata gtgagatagg aggttaattt ctatgaataa
    13321 agaaagtttt ttagctatct tacttctaat ttttgaaagc attattgtaa ttgctgttgg
    13381 ctaaacaaat agaaaataaa gacaccacaa aagttagact ttcgatgtct aacttttgtg
    13441 gtgtagttaa ggtatgatgt tgttctctaa taagggtata atataaaaaa gactctatga
    13501 tttctgtagt aggtaaaacc actatagaga ttatagagct ttttgagtgt atacaaaaac
    13561 tagttcttta ttggaacaaa gtcaacaact aatctagtat tggttgcagc ggcaatttct
    13621 tccaatgttt tatatgttgg attagtggtg ccattctcta tacgtccgat actagcctga
    13681 ctttttccca tacgatcagc aagttcttgc tgagttaaat tgatattctc tcttaattgt
    13741 ttaattttat gcgatagctt tatacactcg atttcattgt tatagtgctg tagaatttca
    13801 ggtgcctttt tactcctttc tgccaagtat gaagcaagaa acccgtttct atccacttta
    13861 tcaagtggtg taagtttgat ttccttcatg tgcatctctc cttaataaaa tatagtcaat
    13921 atccatacta aactttacag tccagtttta aaggttgaat ctttttcagc ccttaaaact
    13981 ggattgcgag aatccagttt gtgtcatcgc ttgttcttat agttcgattt tcgtttgata
    14041 gctttcttca attccttaga tggtgtttta tttgtttttt tcttaaagga gtttgtgatg
    14101 atataagtag gtgaagccac attgtcttct tcttcgttag ctttttctaa acggaaaaat
    14161 aatgaacggg cgaaaatgcc ttccgtatta attctaagct caaagatatc tttttttcta
    14221 tctacttttc tgactaactt tagagccatg gtttctgcta taccgatagc agaaacctct
    14281 cgtatccttg cgataacctt tgacgctaca gttaagggga gggaatctaa aaacgctgca
    14341 aattcgtctt cgtcataata aataaaggtt agtttagagg gggctttatt acttaaggaa
    14401 aaagttatga aacataaaaa aatgaagcaa aaaaggcata aactagccaa agaacgtaag
    14461 aatgtatcag gtgagccagg agaactaatc gctaaacgat attttatgta tttaaagcgg
    14521 ttccaagcag ttggtttttt gaaccctttg caaattcggt taattgctga gacgtttgca
    14581 catattccta ctagttactt cttcgacgaa aatcgtaacg attggtggaa ttattatcaa
    14641 atggaggttg actattgtga aattttgaac ttccagcaca aaaagaaaca cctgattaca
    14701 atcagatgtt tatgtatttt ttaccttagc aaactctcga ttaagataat gttgcaagcc
    14761 ttcaaaaatc tctagtaact ggagataatt agacaaactt gagcgaccag ggatatctac
    14821 cacatccaaa gaaatgcggt ccaagtcctt ttcgtaaaga atacggaagg ataccactgc
    14881 ttgatcagaa aaataattct ctcctgacat aatgtagcac tcataaatga tgccaacagg
    14941 attcgcaacc ttcaactcaa tacgaactgc gcctaagccc aaggcctcca cttgctgaaa
    15001 acgttccaac atagcctgtc gctgactagg aataaaattt gtgatatcca tagtggccct
    15061 cccgactttc cttttgtata ttatagccta aagctgagaa aaatgcttgc gaagggattc
    15121 ctgataagac taccccccat gaatcctcat ctagcttctt tatattctct aaagtctgat
    15181 tttatagtgt ttatcgtaat gtagtaagtg tgttctacat gactaagtac aacatattgt
    15241 tgacgactac caaaaatctc attggaagtt accttatctg cttttaggtc agtctataat
    15301 tctgctacat gctttgtatc gccattccct aaaaagaaaa gtatttagta tgatcgtagc
    15361 ataaatcctt ccacactttg agaaggtaaa ttttaaaatc ctctttatca taacttttta
    15421 ctaaaatagc cagaacatca cattctacta tcattcttat ttctcatctt cgtccattga
    15481 aagcacagac aagaaggctt cttgtggtac ctccaccgaa ccaatggctt tcatacgttt
    15541 cttaccagct ttttgttttt cgaggagttt acgtttacgt gaaacgtcac caccgtaaca
    15601 tttagccaag acgtttttac gaagagcttt gatatctgta cgggcaacaa ttttttgacc
    15661 aatagccgct tggataggaa cttcaaattg ttgacgtgga ataattttct taagtttatc
    15721 aacgataagt tttccacgtt cgtaggcaaa ttctctatgg acaataaagc taagggcatc
    15781 gaccttatca ccattaagga gaatatccat tttcaccaat tgtgaacgac ggtactctga
    15841 caattcatag tcaaaacttg cataaccacg agttgatgac ttcaatttat caaagaagtc
    15901 aaagacgatt tcagcaagtg gaatttgata gataacgtta acacgattat catcaatata
    15961 ttccatggtt tcaaaatcac cacgtttacg ttgcgccaac tccataacag caccaacata
    16021 ctcttgagga accataattt gagctttgac ataaggctct tcaatggcat caatacgtgt
    16081 aggatctgga aattcagatg ggttggacac ttcaagcatt tcaccgtcag tagtgttaac
    16141 atggtaaact actgatggtg cagtcatgat gagatcgatg ttaaactcac gttccaaacg
    16201 ctcttggata acatccatgt gaagaaggcc caagaaacca caacggaaac caaaaccaag
    16261 ggcttgagac gtttcaggct caaattgaag actggcatca ttcaattgga gcttttcaag
    16321 agcctcacgc aagtcgttat atttatttga ctcaattgga taaagaccag caaagaccat
    16381 tgggttcatt tgcttataac catgaagtgg ttctgcggct ggattatccg caagtgtcac
    16441 tgtatcaccg acacgagtat ccgcaactgt cttaattgaa gctgctacat aaccaacatc
    16501 tccagtcgca aggtagtcac ggccaacagc tttaggagtg aaaataccaa cctcagtaac
    16561 gtcaaaggtc ttgccattag acatcatttg aatcttatcg cccgttttaa ccattccgtt
    16621 aaccacacgc acttggagta tgacgccacg atacgcatca taaacagagt caaagataag
    16681 ggcttggaga ggtgcttcca catcaccttg gggcgcagga actttctcaa caatttgttc
    16741 gagaatctct tcgataccaa tgccagcctt agctgatgca agcacagctt ccgaggcatc
    16801 taatccgata acatcttcaa tctctgtacg tacacgctca ggatctgccg ctggaaggtc
    16861 gattttattg ataactggta agatttccaa gtcattatca agtgccaagt aaacattggc
    16921 aagtgtttgt gcttcaatcc cttgagctgc atctaccacc aagatagcac cctcacaggc
    16981 ggcaagggaa cgtgacacct cataagtaaa gtccacatgt cccggtgtgt cgataaggtg
    17041 gaaaatataa gtctcgccgt ctttagcttt gtagttaagc tcaatggcat tcagtttgat
    17101 agtgatacca cgttcgcgct caagatccat actatcaagg agttgtgcct gcatctcacg
    17161 acttgataca gtctcagtct tttccaagat acggtcagca agcgttgatt taccatggtc
    17221 aatatgagca ataatcgaga agttgcgaat cttctcctgt ctttgtttta attcttcaat
    17281 atttggcatt ttattctttc ctaattctta cttgtgattg ttaaaaaacg aaccgtcacc
    17341 tcctattata caaaaaagac aggcatttgc ctatctctaa tatctgcttt atgactgcat
    17401 ttagtccttc ttatttctta aaattatcat tgtagtgctt attaataata gctgaacgct
    17461 tgttctctat tgaactactt gaaaatggag ctaaaccaaa ggctagtaca ataattccca
    17521 atagaataag actaaaaaat gggtgctcag caatatagtg taagatgtct gatatgggaa
    17581 tccaccttta aaaacataat tatttataac tatattatca gaaacattat gttttatcaa
    17641 gcaaaaaaag agagccattc gctctccctt ttaaccttaa tggaattgca taccaccatc
    17701 aacgatgatt gtttgacctg tgatgtagtt tgagtcaggt ccagctagga agctaactgc
    17761 tgctgcaaca tcttcaggtt ctgacaaacg tttgagggta atatctttag caaaagtttg
    17821 cataccccac tcatcatctt taccagcatt ttaccaactt cgtgggcaat gtcaaacatc
    17881 attggagtct taacgatacc tggtgcataa gcatttacag ttatacctga atcagctaag
    17941 tcacgcgcca aagtttgagt aataccacga actacgaatt tagttccacc atatacagtt
    18001 aagttagagt tccctacgac acctgcttgt aaagttgcat tgataatttt accaccatga
    18061 ccaagtgatt taaattgtgc ttgggcagct tgtgcacctc agataactcc accaatatta
    18121 atgttaaatg tatgttgaaa ctgttcttca gtaatagtgt caagggattt tgttggtgcc
    18181 acaccagcat tattaacaac aacattcaag tcgccaaagt gatcaactac tttttggaaa
    18241 gctgctgcta cctcagcttg tttagacaca tctgctacaa cggaaaatgc cttgtcttct
    18301 gacaactcag caactgcttt ttcagcagtt tcagcgtcat agtccaatac cccgacttta
    18361 acaccatctt caaccaagcg ttttgaaatc gcaaaaccaa taccttgacc tgcacctgta
    18421 acaatagcaa cttttgacat acgaaatcct cctctaccaa ttgtagtcac aagcttaacc
    18481 acaagcccta tctcaattgg aatatgctaa gttaatcaag ttctggcaaa gtcattttca
    18541 taggcttttt cttaactcat ttagaatctt accactttat gaaagcgttg ttaataattt
    18601 gtcatgcttt ttgaaagcaa ataagatcac cactagtgac cttatgtgta ttatttttca
    18661 aacttaaacc ctagtgcttc catatcacct aggccaccta aggtggtaac cttagtatat
    18721 cctcgttctt tcagtactcc tgcagcaaat tcagcacgag atcccatttt acaatagagg
    18781 taaatggagg cgtctttttt agctggaatg tcagctgtga aaaactgcgt gtgaggtatt
    18841 aataaagcat ccttaacatg accttctgcg tactcttctg gagtcctgac atcaattaat
    18901 agtccatcct gagctaattc tgattgaatc tgtgctatat ccatcctact caccaaacca
    18961 aatcttaatt tctcgagccg cagattcttc tgaatcagag ccatgaacga tatttggaat
    19021 catgtcacca tctggtgctg ttgcaaagtc tccacgaatc gttccaggag cagcatcccc
    19081 aggattagtt gctcccatca tatcacgcca tgacttaata actcctgggc cggacataat
    19141 accaataact gctggaccac tcatcatgaa ttcagaaata ctagggaaaa aaggtttatc
    19201 agccaattgg gcataatgtt ctttaagacg ttcttcgtca agcatcagca tctccatacg
    19261 ctcaataacg aagccacgtc gctcaattcg atcaagcact tgaccaatta gatgacgttt
    19321 aacagcatct ggtttaataa taaagaatgt tttttgcata ttcccaacct tcatcgtttt
    19381 ctttccattt tatcataaga agtatcattt tgcagagcta aaccttgtat agtctaaaac
    19441 tatatacaca gcaagaaatt aactattttt cattagttcc cataagaaat aatatagatg
    19501 taaatagaca tttcgaggta aatttaatga caaaatctaa attccaatta gtcggttctc
    19561 ttcttcgtcc tgcggatctc cgtaaataca aggacgaaat cgagcatcgt gacgacatcc
    19621 agtatccttt ctatgatgcc cttcctggtt atcaagaaac tgaaactgca tctattaagc
    19681 gaatgtggct gaccaaaaag ctaacggaat tgacatcctt accgatggga agtttggacg
    19741 ttctatgtgg cacttggact ttgtctgggg actcaaaggt attgaacgct acattgctga
    19801 gcatggttat acttttaaag accatgatgg tggtcaatat gaaacacgta aagatatcgg
    19861 tattcgtatc actgagcctc tatcaggtaa aaaccaccac tacctagata tttacaaatt
    19921 ggttaaggct gaagctggtg atgaagatac caaacaaact atctggggac ctgctcatgc
    19981 ctacactgaa cttgctatct ttgatcgatt ggctgttcct ggacaagtct atgaaacaaa
    20041 cgaagaactc aaaaaaggtt tgattaatgc ctataaagaa ttcttggatg aatacaaggc
    20101 tgttggtggt aaaatcgttc aatttgacga ctgcctctgg gaactttttg acccatcaag
    20161 ccctacaagt ttctactcag acggcaatgg tgatttggca gaattggccg atgaatttgt
    20221 tgctatcaat aatgaggttg ttgactatac tcacgaactt ggtttaacgg tttggacaca
    20281 caactgtcgt ggtaattatg aaatccgttc tgctgctgaa ggaacttacg aagacatcgc
    20341 taagaaattc ttggcagagc aacactatga ccgcttcttc cttgaatggg atagcgatac
    20401 agctggtgat atcaaagctc tggaagccct taaagacagt aaagctgaag ttgtatttgg
    20461 gctattgtct tcttaaacga ctgacctaga tgacgaagaa cgtgttctcg atttgcttga
    20521 aaaagcgagt caaatccttc caaaaaaacg tctcttcccc tttcaccaat gtggtttcgc
    20581 ctcatgtgac tcaggtaatg agctggcaac acctcaacaa tgggctaaaa tcaaacaagg
    20641 tcaagaaatc gctaagaaat tctttggcta atcgatattt ctattcgctc ctctctaaaa
    20701 cgaaaagcct tcactcttgt gagggctttt tatgttagca tcaagcatct ataaaagttt
    20761 gcaaatcctt aagagctctt tctgcgattt tttcataacg ctctttcttg tcacgaatac
    20821 gtgggccttc taattctttg ataataccaa agttaacatt cattggttga aaatgtttgc
    20881 tttcagcatg tgtcacataa tatggaaggc taccgattgc tgttgtatga gggaaaataa
    20941 cttcatcttc acccttaaag agacgggctg cattgattcc agcaaccaaa cctgaggcag
    21001 ctgattcaac ataaccttca acaccagtca tttgtccagc aaagaacaga ttagggtttg
    21061 attttgattg gaaggtctgt ttaagcaagt ttggcgaatc catgtaagag ttacggtgca
    21121 ttaccccata acgaacaaat tctgcatttt caagacctgg aatcatttgg aagacacgtt
    21181 tttgctctcc ccatttgagg tgggtttgga aaccaacgat attgtagagg ctaccagccg
    21241 cattgtcctg acgaagctga acaaccgcat aaggtgtctt gaagtcacca tcacgtggac
    21301 ccatataatc ttcaggatac tccaaaccaa ctggtttcat aggaccgtag agcattgttt
    21361 taataccacg tttagccata acctcgatag gcatacaccc ttcaaaatac ttttcttttt
    21421 caaaagaatt caaaggagct tcttcagctg tagtcaaggc ctcatagaag gccatgaact
    21481 cttccttggt cattggacag tttagataag ctgcttcacc cttatcatag cgtgacttaa
    21541 ggtaaacctt gttcatgtcg atagttgctt tatcaacgat tggtgcagcg gcatcataga
    21601 aatagaaccc gtctccaccg ttaagctcat gaatcttttc agctaaagca tcagaagtta
    21661 ggggacctga agcaataact gtaatagcat catcaggaat ttctgtgatt tctttacgga
    21721 taacttcaat taagggatga ctttcaattt cagctgtcac tgcttctgca tagccttcac
    21781 ggtccaccgc catggcacca cctgctggca cacggtgagc ttctccatta cgcataatga
    21841 tagagtccaa acgacgcatt tcttctttta gaagccctac agcattggtc aagctatctc
    21901 cacggaaaga gttagagcaa accaattctg caaaatttgt tgtcttatgc tgtggtgttg
    21961 ctttgacccc acgcatttca taaagtttta ctggaatacc acgtttggca atctgataag
    22021 ccgcctcgga tccggccaaa ccagctccaa tcacgttaat ataatctgct tttgattgag
    22081 acatgacact aatacctctt cggaaacaag atgaaatcct gctcccacaa atctttcttc
    22141 atttttactc ttagtagtat agcaaaaaac tcctcatctg gcgactagga gtcatctgta
    22201 tttaaaaggg gtaaaatgat agtcacttta gcaccacccg tgccattgtc atttgcaaga
    22261 gaaagactac catagtgtaa acgaataata tcattggcaa tagtcagacc aaggccacta
    22321 tgattgcgac tctgtctgct tttatcctct tgataaaata gctgagtagc gttttcaaga
    22381 gatgcaaggg aaaatccagg accagaatca aggcatataa acttgaattc atcttcttct
    22441 accctagcgg tcaggagcaa ctgactgcca ctgggtgtat gctctacggc atttgaaaca
    22501 atattcataa tagctcgatt caacaaggac ttatcccaat tgcctatgct ttctttcgca
    22561 atttccttct tgtcaaatac cacattgatt tgtttcgttt gagctaatga caaggtttga
    22621 tcgtaaatgt cttcaacaaa ttccttaact ggaacttctt caagcgtcag ggtcttcttc
    22681 aaactcattt tgttgagttc tgacaactct tttacataag catcaacctg tgcaatacct
    22741 ttttgaaaat gctctaacaa gtccgtttga ttttcatcca aggacgtcat agctaagagt
    22801 tccgcatttc cacgagcaac tgttaggggc gtctttaagt catgtgtcag ggcagaaatc
    22861 tgattttgtt tatcttgctc tgccttccaa ttttccatca aagactcacg aagtgctata
    22921 cgcatatgat ccaaaccact taaaacctga ttaaattcct taattgtaga ctgagaagtt
    22981 tgaaaatcca aatcttgttg ggaaattttt tcagtaaccc ttaatatagg tttaagttgc
    23041 tgactcaatt tatttgcata ataaaaagtt aaaataataa atatgattaa gatagataca
    23101 aacattgaac caatcatcat aagatcagca ttgggaaaat gctggttcat ccactcatta
    23161 cggtaccgag gtgatagttg ataattgaca atgactatgc catctgatcg ttcaaaagac
    23221 tgaaaa
//
