LOCUS       c00047_JACSUL0..       13581 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JACSUL010000009.1 Streptococcus thermophilus strain 13499c2
            202-13499c2-9, whole genome shotgun sequence.
ACCESSION   JACSUL010000009
VERSION     JACSUL010000009
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 00:49:15
            Original ID  :: JACSUL010000009.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 87215
            Orig. end    :: 100796
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13581
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[92215:100560]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..13345
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..13581
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13581
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             1643..3388
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     289.5; E-value: 3.1e-88)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 313.6; E-value:
                     4.5e-95)"
                     /gene_kind="transport"
                     /locus_tag="ctg47_87"
                     /transl_table=11
                     /translation="MPNQNQWSVFKRLLTYLKPYKFLTFLALTFLLSTTVIKSIIPLVA
                     SYFIDHYLHDMNQAASMILIGYYGLYLLQTLVQYLGNLFFARVSYSIVRDIRRDAFANM
                     EKLGMSYFDKTPAGSIVSRLTNDTETISEMFSGTLSSFISAIFIFVTTLYTMMILDIRL
                     TGLIVLFLPLIVLLVNLYRKKSVAIIEKTRALLSDINAKLSESIEGIHIIQAFNQEKRL
                     KKEFDAINEEHLIYASRSISLDSLFLRPAMSLLKLLAYAVLMAYFGYRGIYLGITAGTM
                     YAFIQYINRLFDPMIEVTQNFSTLQTSMVSAGRVFALIDERTYEPEQRDTAAKVTEGNI
                     RFENVSFSYDGKHQILDNISFSVNKGETIAFVGSTGSGKSSIINVLMRFYEFQSGRVLI
                     DGVDIRDYSQAELRKNIGLVLQDPFLYHGTIKSNIAMYQDLTDEEIKAAAEFVDANHFI
                     DKLPEGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANIDSETEAIVQNS
                     LAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIEHGSHEELLALGGTYHKMYSLQAG
                     AMEGE"
     CDS             3695..3805
                     /locus_tag="ctg47_88"
                     /transl_table=11
                     /translation="MTQFTTELLNFGSIISVVGKTTVEIIELFEMVPPQG"
     CDS             4402..5004
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_89"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.5e-46, bitscore:
                     149.0, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRFRRTFVPQIDMRDCGVAALASVAKYYGSDYSLAHLRELAKTN
                     KEGTTALGLVEAAKKIGFETRAIKAEMSLFEMEDVPYPFIAHVNKDGKLQHYYVIYKST
                     KDYLIIGDPDPSVKVTKMTKERFEKEWTGVTLFMGPEPSYKPHKDKKNGLWDFLPLIFK
                     QRSLIANIVFASLLVTLINILGSYYLQGILDEYVLIK"
     CDS             5001..6554
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 295.4; E-value:
                     1.5e-89)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_90"
                     /sec_met_domain="TIGR01193 (E-value: 2.1e-245, bitscore:
                     809.1, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSTLGIISIGLVVTYVLQQMMTFARDYLLTILSQRLTIDVILSY
                     IRHIFELPMSFFATRRTGEVISRFSDANSIIDALASTILSLFLDFSIVIIVGGVLLIQN
                     SNLFKLVLCSVPIYTLIVFAFMKPFERMNHDVMQSNAMVNSAIIEDINGIETIKSLTSE
                     KVCYQKIDGEFIDYLDNSFRLSKLSILQTSLKQGAQLILNVLILWTGAQLVMGNTISIG
                     QLITFNMLLSYFTNPLENIINLQTKLQSAKVANTRLNEVYLIESEFGQSDDTYQEGIAD
                     GDITVTDLSYKYGFGRDTLTDVCLTIRQGEKISFVGVSGSGKTTLAKMLVNFYQPYKGH
                     IDFNGQNISRIDKKTLRQHINYLPQQSYIFSGSVLENLTLGAARGITQADILKACEIAE
                     IRQDIENMPMGFQTELSDGAGLSGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKQ
                     VIDNLLALKDKTIIFVAHRLSIAERTDRIVVIDHGRVVETGSHQDLMSYPGFYYQLFRK
                     "
     CDS             6570..7937
                     /locus_tag="ctg47_91"
                     /transl_table=11
                     /translation="MNPQLFKSTEFYHRRYHNMSTVLITPLILLVIFLFLFAFFAKKEV
                     TVTSRGSIEPTKVIAVIQSTSDNTIIDNQLVANKVVKKGDTLVQYSETMEASQKEGLQK
                     QLELLKRQESGLKTLQSSLTQGTNLFQEQEDEFGYQSTFNTYLSQAQDIDLGVAKTNTE
                     VNNQAAIASNTGSAIDNQISQLQTQVSEYEALSQAITNHETTLPEGNPHQATLNAYNSQ
                     YATTPDASVTDQYLSQVNTNISSLNASIGNLEIQKAGTGTVVTYDNSDSTKKEALKNQF
                     LQNAGQQLSSVETQINDTESKINQADVLLTNTLIQSPEDGILHLSQADKKATMAATGTE
                     LAQLYPDMTQTQEVAITYYVNSDYVPKLQKGQSVRLTLDKVGNHGTTIIGKLESIDNSA
                     TETERGNVFRVTARASISEKEAQNLRYGLEGRVTSVIDQKTYFNYFKDKLLNLQDQ"
     CDS             7952..8113
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_92"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.6e-08,
                     bitscore: 27.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANNTINNFETLDNHALEQVVGGSGWMDYINGFLKGFGGQRTLPT
                     KDYNIPQA"
     CDS             complement(8131..9471)
                     /locus_tag="ctg47_93"
                     /transl_table=11
                     /translation="MLTTLWLLFLTLLSAGLEIILFLYLMGQKIRLRYFFLLLIFNLAF
                     NFIYNHSSWFIIKFWGEDIYYLLLSFLLSTKTKKPLKIKIFNGLFPDILNNLSLRLITF
                     FIFPFFNISITDYQSSLLISIPSSIAPLCLSFLFIKLFKGSFTILQKQKSNSPIQHIII
                     VANFFMFGYTLLLQILMYLENTTHSSTLELRKLCVVISLVLFFIMIVFLDRNIREMIQG
                     QLDFQKNLQLENLYTYNKHIEGLYNSVRSFRHDYSNLLVTLRLGIDKDDMDIVKEAYDS
                     VLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGME
                     TLDFIIVTSIFLDNAIEGAIQTQNPKITISFWEDHCSQLLSISNTISEEKTETKTIFER
                     GVSNKGRERGIGLANVTEILDNYINVNLETQSNNFSFTQQLTITKKA"
     CDS             complement(9465..10202)
                     /locus_tag="ctg47_94"
                     /transl_table=11
                     /translation="LKIYLLEDNSIQMGRLEDAVAHELMTFGKDLSCVQSFDKPDQLLS
                     AITSNTSDQIFFLDIEIKGEDKKGLDIAKIIRQNNPYAIIAFVTTHIEFMPQAFGVTAY
                     KYINKTLDEASFRKEIGETIAQVFPINATTTDEFFLYKTESQLINLPMDQILYLSTSDI
                     KHHVHLQTIHTLMDIRANLADFKKIHKKLYPCHRSYIVNTDMIISVNLTNYEATLINGQ
                     VLPVSRMKIGKIAQIVEERGRGC"
     CDS             10453..10629
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_95"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.5e-11,
                     bitscore: 37.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENFNTLDLETLASVEGGLSCDEGMLAVGGLGAVGGPWGA
                     VGGVLVGAALYCF"
     CDS             10648..10848
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_96"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1e-08, bitscore:
                     28.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNKQLERFKKLDTNALSNVSGQGYGAQCVIGTTGMTIVGAAFFG
                     IAGAGAGFAGGSTAFCYDTAK"
     CDS             11204..11434
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_97"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 9.5e-19,
                     bitscore: 60.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENFNTLDLETLASVEGGVCSWGGFAKQGVATGVGNGLRL
                     GIKTRTWQGAVAGAAGGAIVGGVGYGATCWW"
     CDS             11630..11845
                     /locus_tag="ctg47_98"
                     /transl_table=11
                     /translation="MIENFDIREELFVIMTKKRLVSLMMSMGFVLVALHNFGEKLNFGL
                     QCLNLIGLCLFLFLMCTVIKDIRSDK"
     CDS             11942..12109
                     /locus_tag="ctg47_99"
                     /transl_table=11
                     /translation="MFKNSKPYLLATILIVMGLANLFRSLDAVHHTINLLGLTVLLYSL
                     LFKKWVQFQK"
     CDS             12439..12840
                     /locus_tag="ctg47_100"
                     /transl_table=11
                     /translation="MKLKNISSSVLRSFRTITAALAVFLISISLSLYKSKISPGTWLTV
                     GALAFVVIFVNGLLYRMLKKRPDSVNLLTIRQSFIVFPVITFLVLSVEFYTLLTFSDTT
                     DRIVLAVLMLLLILCDFLSYLQVKKYFKQ"
     CDS             13091..13345
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_101"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2e-14, bitscore:
                     46.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENLNTLDLETLASVEGGGCSWGGAGGATVQGAIGGAIGG
                     AFGGNVVLPVVGSVPGYLAGGVLGGAGGTVAYGATCWWS"
ORIGIN
        1 ctgattcctc ctatggttat gggtcgggtc attgatgcta tcacatcggg aaaattgacc
       61 aatcagatct tgcttttgaa tctcgtttat ttgcttttgg cggctttagg aatgtactat
      121 ttgcgctatg tttggcggat gtatatcttg gcaacgtctt atcgcttggg acagattatg
      181 cgttcgcggc tttttgagca ttttaccaag atgtcgcctt ctttttacca aaagtaccga
      241 actggtgatc tcatggccca tgccaccaat gatatcaact ctctaacccg tttggctggt
      301 gggggtgtca tgtcagccgt ggatgcgtct atcacagcct tggtgacttt aatcaccatg
      361 ttcttcagca tttcctggca gatgaccctg atggcagtct tacctctacc tttcatggct
      421 tttgcgacta gtcgtttggg acgtaagacc cacaaagctt ttggagaatc ccaggcagct
      481 ttttctgaac ttaataataa ggtacaagaa tcggtgtcag gtatcaaggt aaccaagtct
      541 tttggctatc aggaggctga gctccagtcc ttccaagaga ccaataagat gacttttgaa
      601 aagaatatgc ataccatgaa gtatgacagc ctttttgatc ctttggtctt gctctttgtt
      661 ggctcatctt atgttttgac cctccttgtc ggggccttta tgattcaggc cggtcagata
      721 acggtcggaa atttggtaac ctttattacc tatttggaca tgctggtttg gcccctaatg
      781 gccattggct tcctctttaa tatcacgcag aggggaaatg tgtcctacca acgtatcgag
      841 actcttttag agcaggaatc agatgttcaa gatcccgctt atcctcttcc aagcattgaa
      901 aatggtcgtt tagactttgc gattgaccgc tttgcttttg aggatgagga tactttgcga
      961 gatattcatt tcaccttgga caaggggcaa acccttggtt tggttggacc gactggctca
     1021 ggaaagacgg ctcttgtcaa gttgctcttg cgggagcacg atgtcaatca aggagccatc
     1081 tatttgaatg gacatgacat ccgagactat cgcctatcag acttgcgtag cttgattggt
     1141 tatgttcctc aagaccagtt tctctttgcc agttctattt tagacaatat ccgctttggt
     1201 aatccagatt tctccattga taaggtggaa gaagcgacta agttagctca agtttatgat
     1261 gatatcaagg atatgcctga aggctttgaa acaatcattg gtgaaaaggg tgtcagccta
     1321 tcaggtggtc aaaaacaacg tctggctatg agccgggcca tgattttgaa tccagaaatt
     1381 ttgattttgg atgactcctt atctgcggtt gatgctaaga cagaacatgc cattattgat
     1441 aatcttaagc atactcgcaa ggacaaaaca actattatta ccgcccaccg tctcagtgcg
     1501 gtggtgcacg ctgacctcat cctggtcatg caagatggtc gtatcattga acgtgggcgt
     1561 catgacgact tactagctca aggtggttgg tatgccaaga cctatgagtc tcaacagtta
     1621 gaaatggaag gaggagaagc tcatgcctaa tcaaaaccaa tggtctgtgt ttaagcgtct
     1681 cttgacctat ctcaagcctt acaagttctt gacctttcta gctttgacct tcctcttgtc
     1741 cacaacggtt atcaagagta tcattccctt ggtggcctct tattttattg atcactatct
     1801 tcatgatatg aatcaggcgg caagtatgat tctgattggc tactatggtc tctacctctt
     1861 gcagacacta gtccagtatc tgggaaatct cttctttgcg cgtgtgtcct atagcattgt
     1921 cagagatatt cgtcgagatg cctttgccaa tatggaaaaa ctgggtatgt cttactttga
     1981 caagacccca gcaggttcca tcgtttcccg cttgaccaat gatactgaga ccattagcga
     2041 gatgttctca ggaactctgt ctagttttat ttcggctatc tttatctttg ttaccaccct
     2101 ttacaccatg atgatcttgg acattcgtct gaccgggctt attgtcctct ttcttcctct
     2161 gattgtcctt ttggttaacc tttatcgcaa aaaatcagtg gccatcattg aaaagaccag
     2221 agccttgctt tcagatataa atgccaaact gtcagagagt atcgaaggga ttcacatcat
     2281 tcaggccttt aaccaggaga agcgtcttaa aaaagagttt gatgccatta atgaggaaca
     2341 cctgatttat gccagccgtt ctatatcact ggattctctc tttctacgcc cagccatgag
     2401 tctactgaag ctcctggctt atgctgttct catggcctat tttggctacc gaggtatcta
     2461 tctgggtatc acagcaggta ccatgtatgc ctttatccag tatattaatc gcctctttga
     2521 tcccatgatt gaagtgacac aaaacttctc gactctacaa acctctatgg tctcagcagg
     2581 tcgggtcttt gccttgattg acgagcgtac ctatgagcct gaacagagag acacagctgc
     2641 caaggttact gaggggaata ttcgctttga gaatgtctcc ttctcctatg atggcaagca
     2701 ccagattttg gataatattt ccttctctgt caataaaggt gaaaccatcg cctttgtggg
     2761 atctacaggc tctggaaaat cctctattat caacgtgctc atgcgattct atgaattcca
     2821 atcaggacga gttctcatag acggtgtgga tattcgtgat tatagtcagg cagagctgcg
     2881 caagaatatt ggtcttgtcc ttcaggaccc cttcctctat catggcacaa tcaaatccaa
     2941 tattgccatg tatcaagatt taactgatga agagattaaa gctgctgctg agtttgtcga
     3001 tgccaatcac tttattgata aacttcctga aggctatgat tccccagttt ccgaacgtgg
     3061 ttcaagtttc tcaaccggtc aacgccagct tctagccttt gctagaaccg ttgctagcca
     3121 gcctaaaatc ttgattttgg atgaagcgac agccaatatt gattcggaga cagaggctat
     3181 tgttcaaaac tctcttgcaa aaatgcgtca aggccgtaca accattgcca ttgcccaccg
     3241 cctatcaaca atccaagatg ctaactgcat ctatgtctta gacaagggcc gcatcattga
     3301 acatggtagc cacgaagagc tcctagccct cggcggcacc tatcacaaga tgtacagcct
     3361 acaagcaggc gccatggaag gagagtaagc taatctagac catagcttct atattcgaaa
     3421 agatttctta aaaatcaaaa tcgagtagtg acatttatgt cactactttt ttgttggcta
     3481 ccaccctata ataaaatcat agcttgagag aaaaagctaa aaataattta ggaggttgtt
     3541 agaatgacaa ggcaaacaaa taatacattt gaaacactcg atctcgaggt acttgcaaac
     3601 gttgaggtag tgtaaaataa gttgtgtaaa cacaaaaagg aataaatccg ttatagtaga
     3661 gttgcaaaac attactagaa agagatttat tcctatgact cagtttacca cagaactact
     3721 taacttcggc tctataattt ctgtagtggg aaaaaccact gtagagatta tagagctttt
     3781 tgagatggtg ccacctcaag gttgagtaaa tcaaaagata gaaggcacaa ttactcaagg
     3841 tggaaataag gtgggcatta aggaagggaa cccctctagt gacgctaaaa atagcattga
     3901 cagtgataac aaatacactt acaaagctaa ggaaaattaa accgataatt gagtaatcga
     3961 atctcaagag gctgatttag ccttttttga taggattttt tgagatatgg attgacgttt
     4021 ttcataatgt tatccctttt cggaataaaa ataatcaaat tatgacatca tacgatagag
     4081 ataggctccg aggctatcag cagtcatggt ttcctttgga aataccaggg ctggcacagt
     4141 aataatggtt agatcaaata cgtatgcttg taggactatt ttagaatgtt tccttctaat
     4201 aactattgta taactttgaa atcgatttca atgaacttgt cctaaatgac cccaaatacg
     4261 gcttaaatgg taatagtgga gatgacttta agatttttct taccgtttgg gacgtatggc
     4321 aactttttgg gacgctggct ctttttatcc tgaaaatatg acatactaat catatgataa
     4381 tttgtgatga aagggtttgg tatgtttcgt tttcgtagga cttttgtccc tcaaatagat
     4441 atgagggatt gtggagttgc tgccttggca tcagtggcca agtactatgg ttcagattat
     4501 tcattagcac atctgcgtga gttggcgaag accaataaag aagggacaac tgccttaggt
     4561 cttgtagagg ctgctaaaaa aattggcttt gaaacgagag ctataaaggc tgaaatgtcg
     4621 ctctttgaga tggaagatgt tccttatcct tttattgctc atgttaataa agatgggaag
     4681 cttcaacatt attatgttat ttataaaagc accaaggatt atctgataat tggagaccct
     4741 gatccaagtg taaaagtaac taaaatgact aaagagcgtt ttgagaaaga gtggacaggt
     4801 gttactcttt ttatgggacc ggaacccagt tataaaccac ataaggataa gaaaaatgga
     4861 ctctgggact ttctcccttt gatctttaaa caaaggtcct tgatagctaa tattgtcttt
     4921 gccagtctct tggttacttt aataaatatt ttaggttcct attatttaca aggtattcta
     4981 gacgaatatg tcctaatcaa atgaagtcta ccttaggaat tatctcaatt ggattagttg
     5041 tgacctatgt tttacaacaa atgatgactt ttgcaagaga ttatctctta accatactga
     5101 gtcagcgatt gaccattgac gttatcttgt cctacatacg acatatcttt gaactcccaa
     5161 tgtctttttt tgccacaaga cgtacagggg aggttatctc acgttttagt gatgctaact
     5221 ctattatcga tgctctggct tcgacgatat tatcactttt ccttgatttc tctattgtga
     5281 ttatcgtagg aggcgtgtta ttgatacaaa atagcaatct cttcaagcta gttctttgtt
     5341 cggttccaat ttataccctt atcgtctttg cctttatgaa accttttgag cgaatgaatc
     5401 atgacgtcat gcagagtaat gctatggtta attcagccat cattgaggac attaatggga
     5461 ttgaaaccat aaagtcacta accagcgaaa aagtatgcta tcaaaagatt gatggtgagt
     5521 ttattgacta tctagacaat tcttttcgcc tttctaagtt atctatacta caaacatcat
     5581 tgaaacaagg tgctcaactt attttaaatg tacttatcct ctggacaggt gctcagttgg
     5641 tgatgggaaa taccatttcg ataggacaat tgattacttt taatatgttg ctttcttact
     5701 tcacgaatcc tttggaaaat atcattaacc tgcaaaccaa gttacagtct gctaaggtag
     5761 ctaatactag gctcaatgag gtctatctga ttgaatcaga gtttggacaa agtgatgata
     5821 cctatcaaga aggcattgcg gatggagata tcactgttac ggatttatct tataaatatg
     5881 gttttggtcg tgatactttg actgatgtct gtttgacgat tagacaagga gaaaaaatca
     5941 gttttgttgg tgtcagtgga tctggtaaga ctactctagc taaaatgttg gtcaattttt
     6001 atcaaccata taaggggcac atagatttta atggtcaaaa tattagtcgc atagacaaga
     6061 aaactcttcg tcaacatatt aactatctcc ctcagcaatc ctatatattt agtggtagtg
     6121 ttttagaaaa tcttacttta ggtgcagcac ggggtattac gcaagctgat attttgaaag
     6181 cttgtgaaat agcagaaatt cgtcaagata ttgaaaacat gcctatgggg tttcagacag
     6241 agctgtctga tggagcaggt ctgtctggag ggcaaaagca acgtatcgct ttggcgcgtg
     6301 cactactaac gaaatctcct gtactaatct tagatgaagc aactagcgga ttggatgttt
     6361 tgacagaaaa gcaggttatt gataacctcc tagcactaaa agataaaacg atcatctttg
     6421 tagcacacag gcttagtatc gctgagcgga ccgaccgtat cgtagtcatt gatcacggac
     6481 gcgtagtgga gacaggttct catcaagacc taatgtctta tccaggtttc tattatcaat
     6541 tatttagaaa gtgaggaaaa ggaaacacga tgaatccaca gttgtttaaa agcacagagt
     6601 tttaccatcg tcgctaccac aatatgtcta ctgttttgat tactcccttg attttgttag
     6661 ttattttcct ttttcttttc gctttttttg ctaagaagga agttacagtc acgtctagag
     6721 gaagtataga gccaaccaag gttatcgcag taatccaatc aaccagtgac aataccatca
     6781 tagataatca actggttgct aataaggttg ttaaaaaagg ggacacctta gttcagtatt
     6841 cagagaccat ggaggcatcg caaaaagagg ggcttcaaaa gcaactagaa cttttaaaaa
     6901 gacaggaatc aggtttgaag accttgcaat ctagcctaac gcagggaacc aatcttttcc
     6961 aagaacagga agacgagttt ggttatcaga gtacttttaa cacctaccta agtcaggcac
     7021 aggatattga cttgggtgtg gctaaaacaa atacagaggt taataaccaa gcagcaattg
     7081 cgagtaatac cggttctgct attgataacc agattagtca attgcagact caggtctcag
     7141 agtatgaggc gctctctcaa gctattacca atcatgaaac gactttacct gaaggcaatc
     7201 ctcatcaggc aaccttaaat gcctataaca gtcagtatgc tacgacaccg gatgccagtg
     7261 taacagacca atacctatct caagttaata ccaatatttc gagcttgaat gcttccatag
     7321 gtaatctaga aatccaaaag gctgggacag gcacagttgt aacttatgac aatagtgata
     7381 gcactaaaaa agaagctcta aaaaatcaat tcttgcaaaa tgcaggacag caattgagct
     7441 cagtggaaac acaaattaac gataccgaga gtaaaatcaa tcaggcagat gtccttctga
     7501 ctaataccct catccagtca ccagaagatg gaatcttaca cttgagtcaa gctgataaaa
     7561 aagcaaccat ggctgcgaca ggaactgagt tggcccagct ttatcccgat atgactcaaa
     7621 cccaggaagt tgccattact tattatgtga attcggatta tgtgccaaaa ctgcaaaaag
     7681 gccagtcagt tcgactgacc ttggataagg ttggtaatca cggtaccaca attattggaa
     7741 aacttgagag tattgataat tctgccacgg aaacagaaag ggggaatgtg tttagagtaa
     7801 ctgctagggc aagtatttca gaaaaagaag cccaaaatct acgttacggt ctagaaggtc
     7861 gtgtgacaag cgttattgac caaaagacct acttcaatta ctttaaagac aagttactaa
     7921 acttgcaaga ccaataggag gagaattact gatggctaac aatacgatta ataactttga
     7981 aacacttgat aaccacgctc ttgaacaagt cgtaggtgga agtgggtgga tggattatat
     8041 aaatggtttc ctaaaaggat tcggagggca aagaacgctt ccaacaaaag actataacat
     8101 tcctcaagct taggtataga aaaaaggctg ttaggccttt ttagttattg ttaattgttg
     8161 tgtgaatgag aaattgttac tctgtgtttc taagtttaca ttgatatagt tatctaagat
     8221 ttctgtgaca ttagcaaggc caatgcctcg ctctcgtccc ttgttggaga cacctctttc
     8281 aaatatggtt ttggtttctg ttttttcttc acttatggta ttgctaatag ataatagctg
     8341 tgaacaatga tcttcccaaa agctaatagt aattttaggg ttttgagttt gaatggcacc
     8401 ttcaatagcg ttatctaaaa aaatagaagt gacgataatg aagtccagag tctccatccc
     8461 aatcaagtgg atgggttctg ggatgctaat ctgagcttca ataccttctt cttctgcttg
     8521 taaaactttt gcggacagaa ggcttttcaa agtgttatcc tgaatattaa cgagtctagc
     8581 taagtcaaag tttcttgtat ttaatcgttt atcggattct tgaagcacac tatcataggc
     8641 ttctttgaca atatccatat cgtctttatc tatccccaat cgtaatgtga ctaagagatt
     8701 actataatcg tgtctaaaac tacgaacaga attgtagaga ccttcaatat gtttattgta
     8761 ggtgtagaga ttttctagct ggagattttt ttggaagtcc aattgtcctt gaatcatttc
     8821 acgaatgttt ctgtctaaaa agacaatcat aatgaagaag aggacaagtg aaataacaac
     8881 acagagtttt cgaagctcca aagttgaaga atgagtagtg ttttcaagat acatgaggat
     8941 ctgtaacagt agggtgtacc caaacataaa aaagttagca actataataa tatgttgaat
     9001 cggagaattt gatttctgct tttgaagtat ggtaaaactc cccttgaata atttaataaa
     9061 gagaaatgat agacaaagag gtgcaataga tgaagggatg gatattaata gagagctttg
     9121 ataatcggtg atactaatat taaaaaaagg gaagataaag aaagtaatca atcttaaact
     9181 aaggttgttg aggatatcag ggaagagacc attgaaaatc tttattttta atggtttttt
     9241 agtcttagtg gataaaagga aggagagaag aagataatag atatcctcac cccagaattt
     9301 aatgataaac caagaagagt ggttataaat aaaattaaag gctaaattaa aaataaggag
     9361 taggaaaaaa tacctcagac gaatcttctg tcccattaaa taaaggaaaa gaataatttc
     9421 taggcctgca cttaaaaggg tgagaaaaag tagccataac gttgttaaca tcctctgcct
     9481 ctttcctcaa caatctgtgc aatctttcct atcttcatac gggatactgg taggacttga
     9541 ccattaatta aggtagcttc ataattggtc aagttgacag agataatcat atctgtattg
     9601 acgatatagg accgatggca tgggtagagc tttttgtgta tctttttaaa gtctgccaga
     9661 tttgctcgga tatccatgag ggtatggata gtctggaggt gaacatggtg tttgatatct
     9721 gatgtggata ggtatagaat ttgatccata ggaaggttta ttaattgaga ctctgttttg
     9781 tagagaaaaa actcatccgt ggtagttgcg ttaataggga agacttgagc aatggtttcc
     9841 cctatttctt ttctaaagct agcttcatct aaggttttat tgatgtattt ataggctgta
     9901 acgccaaaag cttgaggcat gaactctata tgtgtagtga caaaggcaat gatagcataa
     9961 gggttatttt gacgtatgat tttagcgata tcaagtccct tcttatcttc acctttaatt
    10021 tcaatatcaa gaaagaaaat ctgatcgctt gtattagaag tgatagctga taacaactgg
    10081 tcaggtttgt caaaagactg gacacaggat agatcttttc cgaaggtcat aagttcatgt
    10141 gctacagcat cttccaagcg acccatctga atagaattat cttctaatag gtaaatcttc
    10201 aaggtctagt cctctctttt atgacgaata ctgtttattg aaaaattgta acataaagaa
    10261 aacggttttt caatttttta tgagtgtaaa atgagaattt ttttctgaat tttagagact
    10321 ggatacatta gaaattacca ttcgggacgt atagccactt tttgggacgc tagctctgat
    10381 agagacactt gaatgctata ctaaagatgt gattgagaga tcacacgata aaaattttag
    10441 gaggtagttg ccatggcaac tcaaacaatt gaaaacttta acaccctcga cctcgaaaca
    10501 cttgctagtg ttgagggtgg gttgtcctgt gatgagggga tgctggcagt aggaggactt
    10561 ggtgcagtag gtggcccgtg gggagctgtc ggtggggtgt tagtaggtgc agccttatac
    10621 tgtttctaat ttgtatggga ggaatttatg aataataaac aacttgaaag atttaaaaaa
    10681 ctggatacaa atgcattgtc taatgtaagt ggtcaaggct atggtgctca atgtgttatt
    10741 ggtactaccg gaatgacgat tgtcggtgca gctttctttg gcatcgcagg tgcaggagct
    10801 ggatttgcag gcggtagcac agcattttgt tatgatacag ctaaataatc ttcatttgag
    10861 ataggtgata caaatgaaga aatacctaat cattttttcg actattgcga tgatatattt
    10921 atatagcaaa gtactattgt catcaggaaa tatctatcaa cttttgttag catcaatagg
    10981 attctttttc tttttatttg gagtctatag gcagtataga aagaattagt taaagctttt
    11041 tcaataagac atggactgaa tcaaaaatga tattcagtct tttttttact actcgggaca
    11101 tatagccact ttttgggacg ctagctctga tagagacact tgtatgctat actaaagatg
    11161 tgattgagag atcacacgat aaaaatttta ggaggtagtt gccatggcaa ctcaaacaat
    11221 tgaaaacttt aacacccttg acctcgaaac acttgctagt gttgaaggtg gtgtatgtag
    11281 ctggggaggt tttgctaaac aaggagtagc tacaggagtt ggtaatggtt tacgactagg
    11341 tatcaaaaca cgtacttggc aaggtgctgt cgcaggagca gctggaggtg ctatcgtagg
    11401 tggtgttggt tatggagcaa catgctggtg gtgatggatt atgtttgatt tgaaaagtta
    11461 tattttaggg atggtttcca tggctgttat gagtttttta gataagccaa ttatgtcatt
    11521 tcttgaaaaa cacaaggcta ccaattccgt taagaagaaa tcttccgtta agaagaaatc
    11581 ctaactgaaa tgtcttgtca attgctggtc tgtgaatagc atgtgaatta tgattgaaaa
    11641 tttcgatata agagaagagt tatttgtaat catgaccaaa aaacgcctag tgtctctaat
    11701 gatgtctatg ggcttcgtcc ttgttgcctt acataacttt ggagaaaaac tgaattttgg
    11761 acttcaatgc ctaaatctta tcgggttatg tttatttctc tttcttatgt gtacggttat
    11821 caaggatata aggtcagaca agtagtgaca tttatgtcac tactttttta tcggcttcca
    11881 atctataata aaattcatag attatgcaca gactagctaa aaacacttta aggagaaaag
    11941 tatgtttaaa aactcaaaac cgtatttact ggctaccatt ctcatcgtaa tgggcctcgc
    12001 taatctattt agaagcttgg atgcagttca ccataccatt aacttgctag ggctaacggt
    12061 gcttctttat agcttacttt ttaaaaagtg ggtacagttt caaaagtaac ctttggtcac
    12121 tttgaacgta agatgcttgc aaatgcttat ttttgatgtt cccgaagtaa aattattctt
    12181 gctaatgata gcggagatta tattatattt gattgcatat ctttgtaata gagaaaacaa
    12241 agatatgtat attcgcctat ttaaagtatc agtactaatg acactactgt attacatctc
    12301 cagtagaatt taatcgctaa gggcttactt gaaatcttac agctgtataa taaaatacag
    12361 agaggaatag agttaaatgt aatagcttat taggtttgca agactgactg aggttattca
    12421 tagtttaggt gttttatcat gaagttaaag aatattagtt cgagtgtatt gcgatctttt
    12481 agaaccatca ctgctgcgtt ggcagttttc cttataagta tcagcctttc tctctacaaa
    12541 agcaagatct cgccaggaac ttggctaaca gtcggagcac tagctttcgt agtcattttt
    12601 gttaatggac tgctctaccg tatgcttaag aagcgtccag attcagtaaa tctgttaaca
    12661 atacggcagt ccttcattgt ctttcctgtc atcacatttc tagtgcttag tgtagagttt
    12721 tacacattac taacattcag tgataccaca gaccgtatag tactagccgt attaatgctt
    12781 ttgttaatcc tctgtgattt tctatcttac cttcaagtca aaaaatattt taaacaataa
    12841 acgcatttgc ttgattattc tgtaagcaat ctataagata tttgcataaa agtgttataa
    12901 taagaaagtg attaagtaaa tatgtgaaaa ttagaggaag atttccaatg attgaaggat
    12961 gttctttagg aattaccatt cgggacatat agccactttt tgggacgcta gctctgatag
    13021 agacacttga atgctatact aaagatgtga ttgagagatc acacgataaa aattttaggg
    13081 ggtagttgcc atggcaactc aaacaattga aaaccttaac acccttgacc tcgaaacact
    13141 tgctagtgtt gaaggtggtg gatgtagctg gggaggcgca ggtggagcga ctgttcaagg
    13201 agctatcgga ggagctatcg gaggagcgtt tggaggtaat gtagttttac cagttgtagg
    13261 ctcagttcct ggttatctag ctggtggtgt tctaggtggt gcaggtggta ctgttgccta
    13321 tggagcaacc tgctggtgga gctaatctat ggtatatttt attataggtt ttgttgttgc
    13381 tttgttaggt aatatctttt tcaaaaaggt caataaaaat aaacataaaa aataatcttg
    13441 aacatatatt gaatagctcc ctgtcaagtg gacaatgaaa taataaaata ttaggcgacg
    13501 gccttgttcc tcatttcaag aggggcaagg ccgttattgc gctcttgaaa acgttgatga
    13561 ttgtaaaaat agatgtaggc a
//
