LOCUS       c00098_JAGDYR0..        9245 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAGDYR010000059.1 Lactobacillus helveticus strain HUL 10
            HUL_10_contig_59, whole genome shotgun sequence.
ACCESSION   JAGDYR010000059
VERSION     JAGDYR010000059
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2022-06-21 17:47:24
            Original ID  :: JAGDYR010000059.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9245
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9245
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3365:6580]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3366..6580
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..9245
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9245
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             complement(37..2310)
                     /locus_tag="ctg98_1"
                     /transl_table=11
                     /translation="MSEKFHGLTQAEADKRLKEDGLNEAPEPEYNFFKEFLSKLWNLSA
                     WVLEGALILECILGKWIQSLFVLLMLLFAAFNGASKKKQSRWVLNTISHKLTPKVAVER
                     DGKWIKIDSKQLVRGDLISLQRGDVLAADVKMVSGKIACDESSITGESKPVKKNIDDTA
                     YAGTTVVEGDGLAIVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFDTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTA
                     DLTGIQDAANLNLLLLDKTGTITENKTAVASWSDLSDLPDKDVLALAGSATDKRNAGII
                     DIAIDEYLKENNIPVMDVEHFTPFTSDTGYSMAEVDGHNVKLGSFKQLSLIDKNANEAV
                     EGINFKAGRSVAVLIDDKLAGVFILQDKVRKDSKSALAELKKRGVRPIMLTGDNQRTAA
                     AVAEQVDLTGNVISIHDFDESTDIDELAGIADVLPEDKLKMVKFFQEKGYIVGMTGDGV
                     NDSPALKQAEVGIAVSNAADVAKRSSKMVLLDDGLSSIVKILDAGHRVYQRMTTWSLAK
                     LARTAELTMLLTFGYFFFNYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     RLAKIAFSLAAGWTVIGIAFFSYLNMHGWSHNSISTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGIVQIADVALTFILALCGLAMAQISWQNLLITVVVALIAAIIIDLIYQPV
                     MKNR"
     CDS             2439..3293
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     73.6; E-value: 3.1e-23)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg98_2"
                     /sec_met_domain="LysR_substrate (E-value: 8.3e-31,
                     bitscore: 96.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 6.6e-24, bitscore: 73.6,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIKQLRYFLVVAEEKQITSAAKRLYIAQPPLSYQLKQLEIELGA
                     QLFKRTAHGIELTDAGQILQSYASEILSLSESVKNQVHKTVSGELGTIAIGMASSSTGL
                     IPMKSFQDLTKFYPEINFDIYEDNTFGIIDKLEKKTIDLGIVRTPYNRNGLNAKTLTTE
                     RMMTVTVDPKLKDKTELRIKDLNEQPLIIYRRFEEIFNQTFAHHGIKPFYAVKCDDSRT
                     AITWAKRKMGIALVPESIASTYAPDDLIPIKHSNWITHLQLVWRKDQKVTPLMKRIIDS
                     LSR"
     CDS             3366..3551
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg98_3"
                     /sec_met_domain="Amidinotransf (E-value: 1e-11, bitscore:
                     34.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLIHVYSEIGKLETVMLHRPGRELENLSPDILNRMLIDDIPYL
                     KIAQKEHDYFAHTLEK"
     CDS             3683..4093
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg98_4"
                     /sec_met_domain="Amidinotransf (E-value: 1.3e-24, bitscore:
                     76.6, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYLIAMPVNEMVKQIIAGIRKNEIQNATPSLADLAEDPDYSFYL
                     DPMLNVYFTCDQQAAIGNGMTINRMTSRARRRESLFMETVLKHHPDFKNANIPIWRDRY
                     THGRLEGGDELILNNHVFSNRYFSNNFRCRNH"
     CDS             4041..4595
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg98_5"
                     /sec_met_domain="Amidinotransf (E-value: 1.9e-50, bitscore:
                     161.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFLAIGISQITSAAAITDLAHSLFGHSSYDTILAIKIPHNHAMMH
                     LDTVFTMINYDQCTVHPFILDKSGKIDIYVLEQDDHGEIKITPETDLIKVLKNYLHLSE
                     IDLIPTGGGDAIAAPREQWNDGSNTLAIAPGEVVTYDRNYVSNDLLRKHGILVHEIHSS
                     ELSRGRGGPRCMSCPLVREDL"
     CDS             4607..4744
                     /locus_tag="ctg98_6"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSLLKCKDYTPTELNYLIDFALHLKELKKIFRMNI
                     "
     CDS             4843..5271
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg98_7"
                     /sec_met_domain="OTCace (E-value: 4.6e-13, bitscore: 39.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="OTCace_N (E-value: 1.2e-24, bitscore:
                     76.8, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAGEIHLGKKESIEDTAKVLGSMFDDIEYRGFAQKDVEDLAKYS
                     GVPVWNGLTDKWHPTQMLSDFMTIKEKFGHLKVLTLAYVGDGRDNVADSLLVAGSMLGV
                     SVHIVTPKPLFTHPDVQKIAEGFAKDSGSRNLITDDIE"
     CDS             5648..6070
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg98_8"
                     /sec_met_domain="AA_kinase (E-value: 4.3e-13, bitscore:
                     39.1, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIVVALGGNAIEAGDNSAAAQEKQVKKTMKVVAKMIENGDQVA
                     IVHGNGPQVGNLLLQQYKGSSKDNLAMPLDTVVSMTQGSIGYWMQKALDDQFKHTNYPH
                     QAVALITQIIVNANDPTFKNPTKPIGPFYTFNEMQR"
     CDS             6239..6580
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg98_9"
                     /sec_met_domain="AA_kinase (E-value: 1.8e-19, bitscore:
                     60.0, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKDDSLQGVAGVIDKDFSAAKLAEDIQADELVILTTVDNAYVNYN
                     QPDQAPIGKIKIDQLKKYLEAGQFAAGSMKPKIEAVIDFVEKTGKTAIITSLRNASKLD
                     DGVGTIVYN"
     CDS             6597..7133
                     /locus_tag="ctg98_10"
                     /transl_table=11
                     /translation="MNIFQEGNPQNIAQVLAGKDYRVALQQAIFKKYPDATLVDINLNI
                     PGPIKNNRYLIKLFDYGIKQLEEIWQNKGYDYKLVKALNNDAGCENFYVLRESSKVVKL
                     STILFEENNKIGRLFDADVLIKGKTALSRQELEYSSRRCYLCNRPAKECARSRRHSVEE
                     MQRYISSLYAKYVNN"
     CDS             7254..8420
                     /locus_tag="ctg98_11"
                     /transl_table=11
                     /translation="MKLKKNQDNLKQIASLIKYAFLKDSDLTTDSNFMPRYDHSDGYGY
                     FDQEKLTSYMMVNKFKAEIFGHHVPLAGIGYVASYPEYRGRGHISKLMKEILFDLHDQK
                     IPVANLAPFSEKFYRHYGFSNSIYQKEYRFSGAALASFRLPRKGKIIRGKWNDLIVQNG
                     VIQLYERQLHIDDERNTIIREAWWWNRLDDYYHHREIAVYFDEAGRPMSYLIYRIIDNC
                     FMADELYSITPQGLLSILGFMAAHIGSIKEFCMTLPEKSLLAELFPEQNELDIQLHPYM
                     MSRIIDFQKVLSCMRPLQEGTFNIEVNYDDQCPWNIGVWQLTNYDHQVKCERKEDELVD
                     FSGPITTWTQILLGRLTMESAIKLGLITDYRIKKLDFVKGKVSFYDYF"
     CDS             8436..8597
                     /locus_tag="ctg98_12"
                     /transl_table=11
                     /translation="MSKQKKVRLLKFLNVVVSGINVVISLLIMFNKYQIRKDKKQISDE
                     GHAPLDEN"
     CDS             8600..9205
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg98_13"
                     /sec_met_domain="LysR_substrate (E-value: 5.7e-19,
                     bitscore: 58.1, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRIAYFNQLGRRQLDRIVDQFKQKHSDVEIELIGMGHDEAFD
                     KLAKNEVDLAISDLRDDQLDFKKEILGQEAVMAILQKGSYPSGVQMINKDDLADLTCFI
                     VAKPEEEAAELHLFKDIYQIRSPFIASNSVEEAALLVASGSGYFLMNEATASLISNDTL
                     QRLFLLSNGQQMWQKIAAFYTNEDVVIKDFILLAKKVY"
ORIGIN
        1 ccccagacac ttcagagtgt ttttgtttta agttaattat ctgtttttca ttactggttg
       61 ataaatcaaa tcaataataa ttgctgcaat taatgcaacc acaacggtaa ttaataagtt
      121 ttgccaacta atttgagcca ttgctaaacc gcataaagct aaaataaagg ttaatgcgac
      181 atcggcaatt tgaacaatac ctacaagttt agatgggtaa tcttgccaga agtatttacg
      241 agttctagta attaatacaa ttaacattgc acttagaact aagtaaacat agaccatggt
      301 agagatagaa ttgtgactcc agccatgcat gttgaggtag ctgaaaaaag cgataccgat
      361 aactgtccaa cctgcagcaa gagagaatgc gattttggct aaccttgcca tattccaatt
      421 ttctggtttg taagtaatat gggtacggtc ggtaccaatc atcatggtaa ccatgttatt
      481 catgattgtg taaataacca tagcatttaa tgccattgga atatagttga agaagaaata
      541 gccgaaggtt aaaagcatag ttaattcggc ggttctggcg agcttagcaa gtgaccaagt
      601 agtcattcgt tgatatacac ggtgaccagc atcaagaatt ttaacaatag agcttaagcc
      661 atcatctaga agcaccatct tacttgaacg cttggcaaca tcggcagcgt tagaaacagc
      721 aataccaact tcagcttgct ttaaagcagg agagtcgtta acaccatcac cagtcatacc
      781 aacgatataa cctttttctt ggaagaattt aaccatctta agtttatctt caggtaaaac
      841 atcggcaatt cctgctaatt catcaatatc ggtgctttca tcaaagtcat gaatagagat
      901 aacgttacca gttaaatcaa cttgttcagc gactgctgcg gcagttcttt gattatcacc
      961 agttaacatg attggacgta cgccccgttt tttaagttct gctaaagcag acttagagtc
     1021 ctttcttact ttatcttgta agataaatac tcccgcaagt ttgtcatcaa ttaacacggc
     1081 aactgagcgt ccagctttaa aattgatgcc ttcaactgct tcatttgcat tcttatcgat
     1141 taatgaaagt tgcttaaatg aacctaactt aacattgtga ccatctactt cagccataga
     1201 atagccagtg tcagaagtaa atggggtaaa gtgctcaacg tccatgacag ggatattgtt
     1261 ttcttttaag tattcatcaa tggcgatatc aatgatacct gcattgcgct tatcagttgc
     1321 actaccggct aaagcaagta catctttatc tggcaaatcg cttaaatcgc tccaactagc
     1381 aactgcagtt ttgttttcag tgattgttcc cgtcttatca agtaaaagca agtttaagtt
     1441 agctgcatct tggataccag ttaaatcagc tgttaagacg ccttctttac ttaaacgggt
     1501 tgcttcaaat gaattggaca atgcaaaggt tgacggcatt gcaaccggaa ttgaagcgat
     1561 gaacatcatg gctaagaatg gcaacatgtt gataaacgta tcaaaattac cacctttaaa
     1621 gaatgaagca atgataataa ctaaggtaag tacaccgtca agtaggcaaa ggtagtaaat
     1681 aatcttagtt aaaagttgtt gcaagtgacc aggtgcagct gaattgttga tcaagttaat
     1741 ggtcttacca cttcttgaat ctttaccagt tgcagtaaca attgctaatc catcgccttc
     1801 aacaacagta gtaccagcat aagctgtgtc atcaatgttc tttttaacgg gcttagattc
     1861 accggtaatt gagctttcat cacaggcgat cttaccgcta accattttta catcggctgc
     1921 aagtacatct ccacgttgaa gtgagattaa gtcgcctcta actaattgct tagagtcaat
     1981 tttgatccac ttaccatcgc gttctacagc caccttaggg gttagcttat gtgaaatggt
     2041 atttaatacc caccgtgact gtttcttctt ggatgcaccg ttaaaagccg caaaaagaag
     2101 catcaacaag acgaacaaag attgaatcca tttgcctaag atacattcga ggattaaggc
     2161 accttctaga acccaggcag aaagattcca taattttgat agaaattcct taaaaaagtt
     2221 gtattcgggt tcaggtgctt cgtttaaccc atcttcctta agtctcttat ctgcttcggc
     2281 ttgagttaag ccatgaaatt tttcagacat tttattccct ccaaatctac cttaataaag
     2341 tagcacatat gttgtttgaa tgaaaatact aaattaaaat ataagatata gaatttttta
     2401 ataagagata caactaaaat aaaaaagata gattattaat gaatattaaa caattacgct
     2461 actttttagt agtagccgaa gaaaagcaaa tcacttcagc agctaaaaga ctatacattg
     2521 cacaaccgcc gctgagttat caattaaagc aactagaaat agaactagga gcacaattat
     2581 ttaagcgtac tgctcatgga attgaattaa cagatgctgg acaaattttg cagagctatg
     2641 ctagtgaaat tctctcttta tcagaaagcg tgaaaaatca ggttcataaa actgtttcag
     2701 gtgaactagg cacgattgca ataggcatgg cttcatcatc aactggacta attcctatga
     2761 aaagttttca agatttaact aagttttatc cggaaatcaa ctttgatatt tatgaagata
     2821 atacctttgg cattatcgat aaattggaaa agaagacaat cgatttagga attgtgcgta
     2881 cgccttataa tcgtaatggc ttaaatgcaa aaactttaac tactgaaaga atgatgacag
     2941 ttactgttga tcccaaatta aaggataaga cggaattaag gattaaagat ctaaatgagc
     3001 agcccctcat tatttatcga agatttgaag aaatttttaa ccagactttt gctcatcatg
     3061 ggattaagcc gttttatgct gttaaatgtg atgattctag aacagcgatt acttgggcga
     3121 agagaaaaat ggggattgct cttgttcctg aatctattgc ttctacgtat gcacctgatg
     3181 atcttattcc tattaaacat agtaattgga ttacgcattt gcaattagtg tggcgcaagg
     3241 atcaaaaggt gacgccttta atgaaaagaa taatagattc actaagccgt taagattgta
     3301 acttctacct aattgatcca taatcattgt aagcggatac ataatttgaa ttaggagacg
     3361 ctataatgac tgacttaatt catgtttatt ccgaaattgg caaattagaa acagttatgc
     3421 tgcatcgacc gggaagagaa ttagaaaatc tttcaccgga tatcttaaat cgaatgttaa
     3481 ttgacgatat tccatattta aaaatagctc aaaaagagca tgactatttt gcccacactt
     3541 tggaaaaata gggagttcat gtcgtttatc tagaagattt attagttcac tatttgacta
     3601 atgaagatgt ccgtacaaaa tttgtagatc aattattaga agaatccaat ataaaaaaga
     3661 agatccatta cattaattac tgatggacta tttaatagca atgccagtaa atgaaatggt
     3721 taagcaaata attgctggta ttagaaaaaa tgaaatacaa aatgcaactc cttcattagc
     3781 cgatctagct gaagatccag attattcatt ttatttggat ccaatgctaa atgtgtattt
     3841 tacttgtgat caacaagcag ctattggtaa tggcatgact attaatagaa tgacgtctag
     3901 agctagaaga cgtgagtcat tatttatgga aaccgtttta aagcatcatc ccgactttaa
     3961 aaatgccaat attcctattt ggcgtgatcg ttacactcat ggacgtttag aaggtggcga
     4021 tgagctgatt ttaaacaatc atgtttttag caatcggtat ttctcaaata acttccgctg
     4081 ccgcaatcac tgaccttgct catagcctgt ttggtcattc tagttatgac acaattttag
     4141 caattaaaat accacataat catgccatga tgcatctgga tacagtcttt acaatgatta
     4201 attatgatca gtgtaccgtt catcctttta ttttagacaa atcaggaaag attgatattt
     4261 atgttttaga gcaagatgat catggtgaga ttaaaattac cccagaaact gatttgatca
     4321 aagtgttaaa gaattatttg cacttatcgg agattgacct aattccaacc ggaggtgggg
     4381 atgcaattgc agccccaaga gagcagtgga atgatggctc gaatactttg gctattgcgc
     4441 caggtgaagt cgttacatat gatcgtaatt atgtatcaaa tgatttgtta agaaagcatg
     4501 gcattttagt tcatgaaatt cattcaagtg agctttctcg tggccgtgga ggtccaagat
     4561 gtatgtcatg tccacttgtt cgtgaagatt tgtaagaggc gtcaaaatga aatatttaca
     4621 aaatgtgttt caaggcagaa gtttattaaa atgcaaagac tatactccaa cggagcttaa
     4681 ctatctaatt gattttgcac ttcatttgaa ggaactaaag aaaatattcc gcatgaatat
     4741 ttaaaaggaa agaatatagc tcttttattt gaaaaatctt caacaagaac acgttcagcc
     4801 tttgtagttg catgcaatga tttaggcgca aatcctgaat atatgggtgc tggtgaaatt
     4861 catttaggta aaaaggaaag tattgaagat actgccaagg ttttgggcag tatgtttgat
     4921 gacattgaat atcgcggttt tgctcaaaaa gatgtagaag atttggctaa atattctggt
     4981 gtccctgttt ggaatggttt aacagataaa tggcatccga cccaaatgtt gtctgacttt
     5041 atgactatta aagaaaagtt tggacattta aaggtactta ctttagctta tgtaggcgat
     5101 ggacgtgata atgttgccga cagtctttta gtggctggca gcatgcttgg agttagtgta
     5161 cacatagtta cgccaaagcc tttattcact caccctgatg tacaaaaaat tgcagaaggt
     5221 tttgccaaag attctggatc aagaaatttg attactgatg acattgaata aggcgttaaa
     5281 ggtgcaaata ttatttatac tgatgtctgg gtatcaatgg gtgaaaatga ctggagtgag
     5341 agaatcaaat tgttaaagcc ttacacggtt acaatgaata tgatgtatat gacacaggca
     5401 ccccggatga tcaactaatc tttatgcact gtttgcctgc gtttcatgat tgaactgcta
     5461 aagttggcaa agaaatttat gaaaaatatg gtctaagtga agtggaagtt acagatgaag
     5521 tctttaactc tcaatacgct tggcaattta ctgaagcgga aaatagattg cattctatca
     5581 aagcaataat ggccgctact ttgggcaatt tgtttattcc gtcagttgat gaaggaagta
     5641 aataaagatg aaaagaatag ttgtagcttt gggtggcaat gctattgaag caggtgataa
     5701 tagtgcagct gcccaagaaa agcaggttaa aaagacaatg aaggttgttg ctaaaatgat
     5761 tgaaaatggt gatcaggtag cgattgttca tggtaatggc ccgcaggttg gtaatttgct
     5821 tttgcaacaa tacaaaggtt caagtaaaga taatctcgct atgccgcttg atacagtagt
     5881 atcaatgact caaggcagta tcggctattg gatgcaaaag gccttagacg atcaatttaa
     5941 acatacaaat tatccacatc aagctgttgc tttaattact cagataatag ttaatgcgaa
     6001 tgatccaact tttaagaatc caactaaacc aattggccca ttttatacat ttaacgaaat
     6061 gcagaggtaa aaaatctatc atcctgaata tacttataag caagatacag gtcgaggcta
     6121 tcgtcaagta gtttcttatc caaagctcgt taaaattatt aatgcaccag gcattgacac
     6181 tttactaaag agcaagtttg ttcctattgc tgccggaggt ggtggaattc ctgttgtagt
     6241 gaaagacgat agtttgcaag gcgtagcagg agtaattgat aaagacttca gtgccgcaaa
     6301 actagctgaa gatattcaag cagatgaatt agttattcta actaccgttg acaatgccta
     6361 cgtgaactat aatcaacctg atcaagctcc tattggaaaa ataaagattg atcaattaaa
     6421 gaagtatcta gaagctggcc aatttgctgc aggcagcatg aagccaaaaa ttgaagctgt
     6481 cattgatttc gtagagaaaa caggaaagac tgcaattatt acttctttaa gaaatgcaag
     6541 taaacttgat gatggagtag gtacaattgt ttataattaa ctgcggtgag atataaatga
     6601 acatttttca agaaggaaat ccgcaaaata ttgctcaggt attagctgga aaagattatc
     6661 gtgtagcttt gcagcaagct atttttaaaa agtatcctga tgcgactttg gttgatataa
     6721 acttaaatat cccggggcca attaaaaata atcgatattt aatcaaatta tttgattacg
     6781 gaattaaaca attagaagaa atatggcaga ataagggata tgactataaa ttagtaaaag
     6841 cattaaataa tgatgctgga tgtgaaaatt tctatgtttt gcgagaatct agcaaagtag
     6901 ttaaattatc tacaatttta tttgaagaaa ataataaaat aggacgatta tttgatgccg
     6961 atgtattaat taaagggaaa actgcacttt cacgccaaga gcttgaatac tctagtcgcc
     7021 gctgctattt atgcaatcgc cctgctaaag agtgtgctcg atcacggcga cactcagtag
     7081 aagagatgca aagatacatt tctagtttat atgcgaagta tgtaaataat taaaacggga
     7141 tgggaggcta atcatcccgt tttttcattt aaatcttaaa aaaagctaac gaaaaataca
     7201 taaaatgttc taaaatataa gtaaagttat gaatatatat tgtaaggaaa actatgaaat
     7261 taaagaaaaa ccaagacaat ttaaaacaaa ttgcttcatt gattaaatat gcttttttaa
     7321 aagattctga tttgactaca gatagtaact ttatgccccg atatgatcat agtgatggat
     7381 atggatattt tgatcaagaa aaattgacca gttatatgat ggtcaataag tttaaagctg
     7441 agatatttgg tcatcatgtt ccactggcag gtattggtta tgtggcatca tatcctgaat
     7501 acagaggacg tggacatata tctaaattaa tgaaagaaat tctttttgat ttgcatgatc
     7561 aaaaaatccc agttgcaaat ctagctccat tttcagaaaa attttatcgt cattatggtt
     7621 ttagcaatag tatttaccaa aaagaatatc gcttttcggg ggctgcactt gcttctttca
     7681 gattaccacg caaaggtaag ataattcgtg gaaaatggaa tgatttgatt gttcaaaatg
     7741 gtgtgattca attatatgaa cgtcagttgc atattgacga tgaaagaaat acgatcatca
     7801 gagaagcttg gtggtggaat agattagatg attattatca tcatcgagag attgctgttt
     7861 acttcgatga agctggtcgg ccgatgagct acttgattta tcgcataatt gataactgtt
     7921 ttatggctga tgaattatat tcaattacgc ctcaaggatt attaagcata ttaggcttta
     7981 tggcagctca tatagggtca attaaagagt tttgtatgac attgcctgag aagtctttat
     8041 tggctgaact ttttccagag caaaatgaat tggatattca acttcatcca tatatgatga
     8101 gtagaattat tgatttccaa aaagtcttgt catgcatgcg cccattgcaa gagggtactt
     8161 ttaacatcga agttaattat gatgatcagt gtccatggaa tattggcgtt tggcaattaa
     8221 ctaattatga tcaccaagtt aagtgtgaac gaaaagaaga tgaactagtt gatttctctg
     8281 gtccaattac aacatggact caaatcttat taggacgttt aactatggaa tccgcaatta
     8341 aacttggttt gatcacagat tatcgaatta aaaagttgga ctttgtaaaa ggtaaagtct
     8401 cattttatga ttatttttag aagaaggtat ccaaaatgag taagcaaaag aaagttagat
     8461 tactaaaatt tttaaacgtg gtagttagtg gaataaatgt ggttatttcg ctattgatta
     8521 tgttcaacaa atatcaaatt agaaaagata aaaaacaaat atcagatgaa ggtcatgccc
     8581 cattggatga aaattaacta tgaaaaaatt gagaatagca tactttaacc aacttggtag
     8641 aagacaatta gatcgaattg tagaccaatt taagcaaaaa cattctgatg tagaaattga
     8701 attaattgga atgggacacg atgaagcttt tgataaatta gccaaaaatg aagttgattt
     8761 agcgattagt gatttgcgcg atgatcagct cgattttaag aaagaaatct taggtcagga
     8821 agcagtaatg gctattttgc aaaagggtag ttatcctagc ggtgttcaga tgatcaataa
     8881 agatgatcta gctgatttaa cctgttttat tgtagctaag cctgaagaag aggctgcaga
     8941 actccattta tttaaagata tttatcagat tagaagccca ttcattgctt caaattccgt
     9001 agaagaggca gcattgttag tagcttctgg atcaggatat tttttaatga atgaagcaac
     9061 cgccagttta attagtaatg atactttaca acgattgttt ttattgtcta atggacaaca
     9121 aatgtggcaa aagattgcag ctttttatac caatgaagat gtagtaatta aagattttat
     9181 tttgttagct aaaaaagtat attaatctat cttggaacag caaaatactg taaaaataaa
     9241 aatgc
//
