GCA_017599395.1 - 9 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

JAGFPI010000010 (original name was: JAGFPI010000010.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	sactipeptide,ranthipeptide	27,942	50,895	sporulation killing factor	RiPP:Head-to-tailcyclized peptide	100%

JAGFPI010000014 (original name was: JAGFPI010000014.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 5.1	NRPS,NRPS-like,betalactone	32,544	83,668	fengycin	NRP	93%

JAGFPI010000002 (original name was: JAGFPI010000002.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 22.1	NRPS	75,194	122,330	bacillibactin	NRP	100%

JAGFPI010000036 (original name was: JAGFPI010000036.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 29.1	terpene	6,238	28,136

JAGFPI010000003 (original name was: JAGFPI010000003.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 33.1	T3PKS	136,174	177,271

JAGFPI010000004 (original name was: JAGFPI010000004.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 44.1	sactipeptide	156,109	177,720	subtilosin A	RiPP:Thiopeptide	100%

JAGFPI010000005 (original name was: JAGFPI010000005.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 55.1	CDPS	95,573	116,319

JAGFPI010000006 (original name was: JAGFPI010000006.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 66.1	NRPS	33,518	98,906	surfactin	NRP:Lipopeptide	82%

JAGFPI010000008 (original name was: JAGFPI010000008.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 85.1	terpene	94,248	115,054

No secondary metabolite regions were found in these records:: JAGFPI010000011 (original name was: JAGFPI010000011.1); JAGFPI010000012 (original name was: JAGFPI010000012.1); JAGFPI010000013 (original name was: JAGFPI010000013.1); JAGFPI010000015 (original name was: JAGFPI010000015.1); JAGFPI010000016 (original name was: JAGFPI010000016.1); JAGFPI010000017 (original name was: JAGFPI010000017.1); JAGFPI010000018 (original name was: JAGFPI010000018.1); JAGFPI010000019 (original name was: JAGFPI010000019.1); JAGFPI010000001 (original name was: JAGFPI010000001.1); JAGFPI010000020 (original name was: JAGFPI010000020.1); JAGFPI010000021 (original name was: JAGFPI010000021.1); JAGFPI010000022 (original name was: JAGFPI010000022.1); JAGFPI010000023 (original name was: JAGFPI010000023.1); JAGFPI010000024 (original name was: JAGFPI010000024.1); JAGFPI010000025 (original name was: JAGFPI010000025.1); JAGFPI010000026 (original name was: JAGFPI010000026.1); JAGFPI010000027 (original name was: JAGFPI010000027.1); JAGFPI010000028 (original name was: JAGFPI010000028.1); JAGFPI010000029 (original name was: JAGFPI010000029.1); JAGFPI010000030 (original name was: JAGFPI010000030.1); JAGFPI010000031 (original name was: JAGFPI010000031.1); JAGFPI010000032 (original name was: JAGFPI010000032.1); JAGFPI010000033 (original name was: JAGFPI010000033.1); JAGFPI010000034 (original name was: JAGFPI010000034.1); JAGFPI010000035 (original name was: JAGFPI010000035.1); JAGFPI010000037 (original name was: JAGFPI010000037.1); JAGFPI010000038 (original name was: JAGFPI010000038.1); JAGFPI010000039 (original name was: JAGFPI010000039.1); JAGFPI010000040 (original name was: JAGFPI010000040.1); JAGFPI010000041 (original name was: JAGFPI010000041.1); JAGFPI010000042 (original name was: JAGFPI010000042.1); JAGFPI010000043 (original name was: JAGFPI010000043.1); JAGFPI010000044 (original name was: JAGFPI010000044.1); JAGFPI010000045 (original name was: JAGFPI010000045.1); JAGFPI010000046 (original name was: JAGFPI010000046.1); JAGFPI010000047 (original name was: JAGFPI010000047.1); JAGFPI010000048 (original name was: JAGFPI010000048.1); JAGFPI010000049 (original name was: JAGFPI010000049.1); JAGFPI010000050 (original name was: JAGFPI010000050.1); JAGFPI010000051 (original name was: JAGFPI010000051.1); JAGFPI010000052 (original name was: JAGFPI010000052.1); JAGFPI010000053 (original name was: JAGFPI010000053.1); JAGFPI010000054 (original name was: JAGFPI010000054.1); JAGFPI010000055 (original name was: JAGFPI010000055.1); JAGFPI010000056 (original name was: JAGFPI010000056.1); JAGFPI010000057 (original name was: JAGFPI010000057.1); JAGFPI010000058 (original name was: JAGFPI010000058.1); JAGFPI010000059 (original name was: JAGFPI010000059.1); JAGFPI010000060 (original name was: JAGFPI010000060.1); JAGFPI010000061 (original name was: JAGFPI010000061.1); JAGFPI010000062 (original name was: JAGFPI010000062.1); JAGFPI010000063 (original name was: JAGFPI010000063.1); JAGFPI010000064 (original name was: JAGFPI010000064.1); JAGFPI010000065 (original name was: JAGFPI010000065.1); JAGFPI010000066 (original name was: JAGFPI010000066.1); JAGFPI010000067 (original name was: JAGFPI010000067.1); JAGFPI010000068 (original name was: JAGFPI010000068.1); JAGFPI010000069 (original name was: JAGFPI010000069.1); JAGFPI010000070 (original name was: JAGFPI010000070.1); JAGFPI010000071 (original name was: JAGFPI010000071.1); JAGFPI010000072 (original name was: JAGFPI010000072.1); JAGFPI010000073 (original name was: JAGFPI010000073.1); JAGFPI010000074 (original name was: JAGFPI010000074.1); JAGFPI010000075 (original name was: JAGFPI010000075.1); JAGFPI010000076 (original name was: JAGFPI010000076.1); JAGFPI010000077 (original name was: JAGFPI010000077.1); JAGFPI010000078 (original name was: JAGFPI010000078.1); JAGFPI010000079 (original name was: JAGFPI010000079.1); JAGFPI010000007 (original name was: JAGFPI010000007.1); JAGFPI010000080 (original name was: JAGFPI010000080.1); JAGFPI010000081 (original name was: JAGFPI010000081.1); JAGFPI010000082 (original name was: JAGFPI010000082.1); JAGFPI010000083 (original name was: JAGFPI010000083.1); JAGFPI010000084 (original name was: JAGFPI010000084.1); JAGFPI010000085 (original name was: JAGFPI010000085.1); JAGFPI010000086 (original name was: JAGFPI010000086.1); JAGFPI010000009 (original name was: JAGFPI010000009.1)

Compact view

c00001_JAGFPI0.. - Region 1 - ranthipeptide,sactipeptide

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Location: 27,942 - 50,895 nt. (total: 22,954 nt) Show pHMM detection rules used

sactipeptide: (subtilosin or thuricin or TIGR04404 or Subtilosin_A or skfc)
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

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Gene details

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KnownClusterBlast

Sactipeptides

Similar known gene clusters

Sactipeptide predictions

Sactipeptides - No core peptides found.

Sactipeptides

Core peptide predictions

No core peptides found.

c00005_JAGFPI0.. - Region 1 - NRPS,NRPS-like,betalactone

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Location: 32,544 - 83,668 nt. (total: 51,125 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 32543 - 83668:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (glu)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 32543 - 78672:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (glu)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 42747 - 83668:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (glu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg5_53

Search NORINE for peptide: strict or relaxed

AMP-binding (463..864): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: glu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWHFGGVDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 100% (strong)

AMP-binding (1502..1896): tyr

NRPSPredictor2: tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: tyr, bht
Single AA prediction:: tyr

Stachelhaus prediction details:

Stachelhaus sequence:: DGTITAEVAK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 100% (strong)

ctg5_56

Search NORINE for peptide: strict or relaxed

AMP-binding (1..293): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFYGITFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 100% (strong)

ctg5_63

Search NORINE for peptide: strict or relaxed

AMP-binding (13..445): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: N/A
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: gclhIAApvK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 40% (weak)

c00022_JAGFPI0.. - Region 1 - NRPS

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Location: 75,194 - 122,330 nt. (total: 47,137 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 75193 - 122330:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg22_101

Search NORINE for peptide: strict or relaxed

AMP-binding (463..861): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

AMP-binding (1519..1935): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

ctg22_103

Search NORINE for peptide: strict or relaxed

AMP-binding (31..435): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

c00029_JAGFPI0.. - Region 1 - terpene

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Location: 6,238 - 28,136 nt. (total: 21,899 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

c00033_JAGFPI0.. - Region 1 - T3PKS

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Location: 136,174 - 177,271 nt. (total: 41,098 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

c00044_JAGFPI0.. - Region 1 - sactipeptide

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Location: 156,109 - 177,720 nt. (total: 21,612 nt) Show pHMM detection rules used

sactipeptide: (subtilosin or thuricin or TIGR04404 or Subtilosin_A or skfc)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Sactipeptides

Similar known gene clusters

Sactipeptide predictions

Putative Sactipeptide(s)

ctg44_175 leader / core peptide: MKKAVIVENK - GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

Sactipeptides

Core peptide predictions

ctg44_175: Putative sactipeptide; RODEO score: 33.0; Core sequence, approximate: GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

c00055_JAGFPI0.. - Region 1 - CDPS

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Location: 95,573 - 116,319 nt. (total: 20,747 nt) Show pHMM detection rules used

CDPS: (CDPS or cycdipepsynth)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

c00066_JAGFPI0.. - Region 1 - NRPS

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Location: 33,518 - 98,906 nt. (total: 65,389 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 33517 - 98906:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (glu - leu - D-leu) + (val - asp - D-leu) + (leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg66_58

Search NORINE for peptide: strict or relaxed

AMP-binding (469..867): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGCVFK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

ctg66_59

Search NORINE for peptide: strict or relaxed

AMP-binding (470..864): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWIGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 100% (strong)

AMP-binding (1501..1904): asp

NRPSPredictor2: asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGHVGK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 100% (strong)

AMP-binding (2546..2933): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

ctg66_60

Search NORINE for peptide: strict or relaxed

AMP-binding (466..867): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAKDLGVVDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 100% (strong)

AMP-binding (1510..1908): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAFMMGMVFK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

AMP-binding (2550..2938): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

c00085_JAGFPI0.. - Region 1 - terpene

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Location: 94,248 - 115,054 nt. (total: 20,807 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

KnownClusterBlast

Similar known gene clusters

No matches found.