LOCUS       c00044_JAGFPI0..       21612 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAGFPI010000004.1 Bacillus subtilis strain ASM-1
            NODE_4_length_193275_cov_65.222124, whole genome shotgun sequence.
ACCESSION   JAGFPI010000004
VERSION     JAGFPI010000004
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-21 03:08:13
            Original ID  :: JAGFPI010000004.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 156108
            Orig. end    :: 177720
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21612
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[166108:167720]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     CDS             complement(11..358)
                     /locus_tag="ctg44_161"
                     /transl_table=11
                     /translation="MSLESVRTHFKQWNLENDVTEFETSSATVEQAAETTGVSPARIAK
                     TLSFRGEGDQAILIVAAGDAKIDNKKSRQHLALKQECSLLMRYWSRQAMKLEEFAHLDR
                     LMILRFILMYR"
     CDS             complement(456..575)
                     /locus_tag="ctg44_162"
                     /transl_table=11
                     /translation="MKLKSKLLLSCLALCTVFVATTIANAPTHQIEVAQRGMI"
     CDS             complement(559..1704)
                     /locus_tag="ctg44_163"
                     /transl_table=11
                     /translation="VTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDY
                     ARQAYEIYKENEAYNIRLLQCHSLFATNFLDLKQYEDAVSHFQKAYSMAEAEKQPQLMG
                     RTLYNIGLCKNSQSQYEDAIPYFKRAIAVFEESNILPSLPQAYFLITQIHYKLGKMDKA
                     HEYHSKGMAYSQKAGDVIYLSEFEFLKSLYLSGPDEEAIQGFFDFLESKMLYADLEDFA
                     IDVAKYYHERKNFQKASAYFLKVEQVRQFIQGGVSLYEIEV"
     CDS             1934..2383
                     /locus_tag="ctg44_164"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISDITIENLVVVPPF"
     CDS             2414..3289
                     /locus_tag="ctg44_165"
                     /transl_table=11
                     /translation="VLVPEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIE
                     ITPDKSAVFVLHPNNNVISVIDYDTLTVTATIMLDQPPRLIRFIPNHEFAYVFTGTAIY
                     VIGIDTLTVERSIPVEGFDIAIDPNGLFAYVLNFGLVQKVDLSTGEVLGTIERELIVSS
                     IETDSTERYAYVLEQEFLFNYLTVIDLNTFTIRDTQELEPDGLYVMFTSGSEVYLHDSF
                     TGNLYSVSPNGAGVIGNLPQSATDYAFTPNGDFLYATRFIEQSIIVYNTDDYSEETVIS
                     LGVSPGAITI"
     CDS             3328..3663
                     /locus_tag="ctg44_166"
                     /transl_table=11
                     /translation="MKKNDLSALQVNCFCFCDEEISREAPFQVPIDFPEGFKVDTAEAS
                     AAVTWSTDNLSCISEPCLIQTGPEPEDIGVRYAVRVQGTITLLVSVSPVRNQYGQGNGA
                     VSVISTV"
     CDS             3686..4669
                     /locus_tag="ctg44_167"
                     /transl_table=11
                     /translation="MTVEDLLIVPPFYGSPLTVTGTLVLPPSPDPQSYVFTANTGDSTV
                     SVIDADLNTVVKTIPFSDVPTNLGVTFDKAFTYVLHGNTNLVSVIDNKTLTIINTITVG
                     GGPRKIEFDPTDEFAYVMAAGSIYVINTASQSVIDVIPIPGALDFALDPNGQYVYTANG
                     SSWSVDKYDINTGQLVESIIDTFEFPSLIATPYAGNFAYVLNGELWPKGVTEISLSPLS
                     RGGDFSRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTARQRIIANVSLPGAF
                     DLAVTPDKQYIYAAQPNDNAVTVYRTSGYTAVTVIPVGAGPSAIAM"
     CDS             complement(4675..5376)
                     /locus_tag="ctg44_168"
                     /transl_table=11
                     /translation="MKKSTVFTLLLLLIGMAAYSFGWVQAVAEAAAQYVQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDSYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGALAAAGIWWMLSFSISELLFLIILATIQQIGSFIYKR
                     FSYRSTASLDL"
     CDS             complement(5373..6653)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_169"
                     /sec_met_domain="Peptidase_M16 (E-value: 1.2e-14, bitscore:
                     48.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKSFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQAHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMVLGDEERMEDTWTGLQIGALPGQNDLLAIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     CDS             complement(6658..7842)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_170"
                     /sec_met_domain="Peptidase_M16_C (E-value: 3.7e-06,
                     bitscore: 20.7, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LIQAKENGLEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYF
                     YGAAAYLKEQIIDAFGYAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALMKT
                     FADLSFPSSLSFEAVEKARNELLLKIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRK
                     DRIKAIHPKRFLDATDFTVDLVSQQKQLNILGQVQACDVRGHAPQTSAITSERIPVNRH
                     VFETETRSAAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAV
                     YHVITRYDVMNNLLLVSICTDQLHEIDIPPRVLEAVSAFHTDERELEQAKQFLRNELLL
                     QFDSPEGLLAYMGVLRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     CDS             complement(7808..9118)
                     /locus_tag="ctg44_171"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     WMFLLHAAIFACVCLSAALMPAATIPLCAIHILWAVIIDFPVFLQAPPQQGKMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVIYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLLAGGFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPSFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     CDS             complement(9111..9830)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 127.7; E-value:
                     9.5e-39)"
                     /gene_kind="transport"
                     /locus_tag="ctg44_172"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKMREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     CDS             complement(9827..9988)
                     /locus_tag="ctg44_173"
                     /transl_table=11
                     /translation="LSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGI
                     RARKADSR"
     CDS             complement(10001..11347)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_174"
                     /sec_met_domain="PF04055 (E-value: 5e-23, bitscore: 75.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1079.5, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.6e-08, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.4e-11, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 7.7e-11, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 2.4e-30,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIAHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     CDS             complement(11481..11612)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_175"
                     /sec_met_domain="Subtilosin_A (E-value: 4.2e-30, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       complement(11583..11612)
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="ctg44_175"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       complement(11481..11582)
                     /prepeptide="core"
                     /locus_tag="ctg44_175"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[11582:11612](-)"
     CDS             11925..12353
                     /locus_tag="ctg44_176"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFITGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     CDS             12350..14020
                     /locus_tag="ctg44_177"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLEFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     CDS             14114..15343
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 106.1; E-value: 2.7e-32)"
                     /gene_kind="transport"
                     /locus_tag="ctg44_178"
                     /transl_table=11
                     /translation="MIRLIIESLKGASQMINRQHIQLSLQSLSLVAGFMVWVLISSLIS
                     QITLDIHLSKGEISLVTAIPVILGSLLRIPLGYLTNRFGARLMFMVSFILLLFPVFWIS
                     IADSLFDLIAGGFFLGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAVTTFAA
                     PVIAQAVGWKSTVQMYLILLAVFALLHVLFGDRHEKKVKVSVKTQIKAVYRNHVLWFLS
                     LFYFITFGAFVAFTIYLPNFLVEHFGLNPADAGLRTAGFIAVSTLLRPAGGFLADKMSP
                     LRILMFVFAGLTLSGIILSFSPTIGLYTFGSLTVAVCSGIGNGTVFKLVPFYFSKQAGI
                     ANGIVSAMGGLGGFFPPLILASVFQATGQYAIGFMALSEVALASFVLVIWMYWQQRMKT
                     HTERNSQSIN"
     CDS             15442..16158
                     /gene_functions="regulatory (smcogs)
                     SMCOG1133:Transcription regulator, crp (Score: 124.1;
                     E-value: 8.2e-38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg44_179"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDLISSDLHELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VERSDGILINIVLTNQDLAKFCAAARESVNRMLGDLRKKGVISIDESGKIILHKRDYLR
                     CEIECENCPLEICNID"
     CDS             complement(16190..16909)
                     /locus_tag="ctg44_180"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFLLGMVKGGPVIWHIPLFLGWLFLYLA
                     VYPVTLALKKKQSKPYQKWMCYYGFPACCFLMISVFHKPPLIWVGVSLLPLFLIHMYFA
                     RRKNERALLNDVAGVLFFCSGGFASCWLGMGTLDGWAWFIFLQSALFFIGSSFYVKSVI
                     RERKNRTFAYWSWGYHLLLPFLSALFGAGWSFLAFIPSSLRAWFFHGRDWPVKTIGILE
                     IVNACFFLAVMCLFITR"
     CDS             17053..17529
                     /locus_tag="ctg44_181"
                     /transl_table=11
                     /translation="MNQCDYLLFLKQLPMFNEVPLSIVETLLKNGTFIRGSCDQSPSFL
                     HSQSVYIVLKGSVRFMDTRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFISVNATSDIL
                     ILNIPYYIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS"
     CDS             17746..21432
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134:flavodoxin (Score: 80.3; E-value: 1.6e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_182"
                     /transl_table=11
                     /translation="MKKKKRSPLFRRLNYFSPIEHHSNKHSQTTREDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLINLWREALQEHQNPLEAWKSIVENPEKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFIEYAKQYTD
                     FPFLVTLSKENGVYTAGRFLHAKDIGRKTKHDQWKPAVWDEQTSSFAIPQGTMGSRWDG
                     QQKWNLHMIDEETGEPIEPRLSVLGIEDEIGTVRIPYFSNDGNKVLERDLPIKKMNLNG
                     EETYVTTVFDLILANYGVNRGIGEQQAVSYDDPEPFTPAWQEQMTGIKKEAVVKIAREF
                     AQNAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIATAKDWEGVPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFNQNGIDLYKEAEKAGAATPEDVGAYVASQLQEKKLKFAIEDP
                     DNEVNFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAVSDLAEEVNMEPVKEVVATPLLHDTMQELAQPFGKINDWSKGECEAI
                     PGKTMPNIQVVERDYKHIFHKMTALGPNAALKPSGTKGMSWSIADEYESLKKRLGEITS
                     DSVAKGCPNISEAKQAAEAVLTLSSTSNGKVAVKAWESLENITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFTGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAEDTDIKDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
ORIGIN
        1 tcaaaccgtt tcagcgatac atcaagataa acctcaggat catgagccga tccaaatggg
       61 caaactcctc caatttcatg gcctgtctgc tccagtacct cattaggaga gagcattctt
      121 gctttaaagc caaatgttgc ctggactttt tgttgtcgat cttggcatcg ccggctgcca
      181 caatcagaat cgcctgatct ccttcccctc tgaaggacag ggtcttggcg attctagccg
      241 ggctcacgcc ggtcgtctca gctgcctgtt caactgtcgc gctcgacgtt tcgaactccg
      301 tcacatcatt ttctagattc cactgtttaa agtgggttct cacactttcc agagacatgc
      361 tgcatttcca ctatttttaa gattattgaa aaaatcttag catggattgg gagactgggt
      421 aaagagggga caaaaaaacc gccgatggac ggcggttaaa tcattcctcg ttgtgcaact
      481 tcaatttggt gtgtaggtgc atttgcaata gttgttgcca cgaacacagt gcatagagcc
      541 agacaagaga gtaatagttt agacttcaat ttcatacaaa ctcactcctc cttgaataaa
      601 ttgccttact tgttccacct tcaaaaaata agcagaagct ttttgaaaat ttttacgttc
      661 atgataatat tttgccacat caatagcgaa atcttcaaga tcagcataca acattttact
      721 ttcgagaaaa tcaaaaaatc cttgaattgc ttcttcatcc ggccctgata agtataaaga
      781 tttcaaaaat tcaaactctg ataaatatat tacatctccg gccttttgtg aataagccat
      841 tcccttacta tgatattcat gagctttatc catttttcct aatttataat ggatctgtgt
      901 aattaaaaaa tacgcttgag gtaaggaagg aagaatattt gattcttcaa aaacagctat
      961 tgctcttttg aaataaggta tggcatcctc atattggctt tggctgtttt tacaaagccc
     1021 gatattgtac aaagttcttc ccattaattg gggctgcttt tcagcttctg ccatagaata
     1081 agctttttga aaatgtgaga cggcatcctc atactgtttt aaatctaaaa aattggtggc
     1141 aaataaagaa tgacactgca gcaatcttat attataagct tcattttctt tgtatatttc
     1201 atatgcttgc cgtgcatagt ccattgaaaa atacgtttgt ttcatatagt aataagattc
     1261 agacatctta aagaaaaact cagctttctc tatccgatcc ttaacgaata tcagcttgct
     1321 ttcggccttt ttgaaaaatt taatagccga cagatattcc cgctgatcca gctcatacat
     1381 gcctctgaag aaattaaaat agtactcaag cagaccagtt aaacgagcct gttttttatc
     1441 aatctcaagc agcagatcag acagtctcgg ctgttcctca atcctcattt tttctaacgg
     1501 ttcaaggtac tcaagcatca ggttgtgccg aaactccatc agtgaatagt acaaatgaag
     1561 gtcttgatct tcttccattt gatccagctc ttgcttgatt tctcgtcgca aatattctgc
     1621 atcgggtatg ctaaatcggc gtatgtacat ataccattcg ttaatctttt ctccgatgga
     1681 agaagaagat atgacacctg tcacgtttgc aaatccctcc cttcataatt ctatatatgt
     1741 catattttat catcaacatt cttgtgagaa gcgcaaaaaa accgcaattt tttctttcgt
     1801 tacaccgcat gtttggagat atattttcaa aaagaagcgt ttaccctcag caatttgtac
     1861 aagcaaacac gttactcttc catattctgt tatatctgcg tgagcagtgt atgtctgaaa
     1921 aggaagtgaa ggaatgagaa aaaataagct ttcctttaaa gaaaaagcag gagcagaaca
     1981 agaagagtgc ttatgttttt gtgagggaga agcaagccga gaagccatgt ttcaagcgcc
     2041 gattgaatta cctgaagggt ttgtcgttga tccggctgaa gctgttgcaa acgtgacgtg
     2101 gaatgcagac agcctttctt gtgtcagtga ccgttgctta attcaaacgg ggccagagcc
     2161 tgatgaggtc ggtgttcaat ttgcagtgcg cctgcaggga accgttacgc tactcgtcag
     2221 tgtctcacct gtgcgaaatc aatatggaca aggggacggg gctgtttccg tcattcacaa
     2281 tgcagaaatc gatcaagtcg tctattattc cgatgaaccg gatgattgcc cggatatcag
     2341 tgacatcacg attgagaacc ttgttgttgt tccgccgttt taaggcagtc ctttatcggt
     2401 aacggggacg attgtgcttg taccggagcc ggaacccgtc tacgcgttta cagcgaatcc
     2461 aaatgatcaa tcagtttctg tgattgatac aaacacccat actgttgtga caacgattgc
     2521 tcttccgtac aatccggcag gtattgaaat tacgccagat aaaagcgctg tgtttgtctt
     2581 acatcccaac aataatgtga tttctgtcat cgattatgac acattaacag tgacagcaac
     2641 tataatgctg gatcagccgc ctcgattgat tagatttatc cctaatcatg agtttgctta
     2701 tgttttcacc ggtactgcca tttatgtgat tggaattgat acgttgactg ttgagaggtc
     2761 tattcctgta gaaggttttg atattgcaat tgaccccaat gggttgttcg cctatgttct
     2821 taattttggg ttagtgcaaa aagtggactt atctaccggt gaagtcttag gaacgattga
     2881 acgagagctt atcgtatcat ccatagaaac agattctacg gagcggtatg cgtatgtatt
     2941 agaacaagaa ttcttattca attatttgac ggttattgat ttaaatacgt ttacgatcag
     3001 ggatacccaa gagctggagc ctgacgggct atatgtaatg tttacgagtg gatcagaggt
     3061 gtatttacat gacagcttca ctggcaattt atattctgtc agtccgaatg gagcaggtgt
     3121 aattggaaat cttccgcaat cagcaacaga ctatgcgttt accccgaatg gcgattttct
     3181 gtatgcaact cgttttatag agcagagcat cattgtttac aacacagatg attattctga
     3241 ggaaactgtg atatctcttg gggtttcacc gggtgccatt acgatttaac cgctgcatgt
     3301 tgtgcatttc taaaaggacg tgaaatcatg aaaaagaatg atctttctgc tttacaggta
     3361 aattgtttct gtttttgtga tgaggaaatt agccgggaag cgccgtttca agtgccgata
     3421 gatttccctg agggcttcaa ggttgatacg gccgaagcgt cagcggctgt tacatggagt
     3481 acagacaatt tgtcctgtat cagtgagcct tgcttaatcc agactgggcc ggaaccagaa
     3541 gatatcggtg ttcgatatgc tgtgagagta caagggacca ttacgcttct tgtcagtgtg
     3601 tcgcctgtgc gaaatcaata tggacaaggc aatggggcgg tttctgtgat cagcacagtc
     3661 tgaccgctgt cctgatttta gtcaaatgac agtggaagat ctgctcattg taccgccttt
     3721 ctacggcagt ccgctcacgg tgaccgggac acttgtttta ccgccatcac cagaccctca
     3781 atcgtatgtg tttactgcca atactggaga cagcacggtt tcggttattg atgcagattt
     3841 aaacactgtt gtaaaaacaa tccctttttc tgacgtgcca actaatctag gcgttacttt
     3901 cgataaagca ttcacgtatg tcctccatgg aaataccaac cttgtctcag tgattgataa
     3961 taaaacatta accatcataa ataccattac tgttggagga gggccgagaa agatcgaatt
     4021 tgatccaaca gatgagttcg catacgtgat ggccgccgga tctatatatg tgattaacac
     4081 ggcctctcaa tcggtcattg atgtcattcc gatacccggc gctttagact ttgctcttga
     4141 tccgaatgga cagtatgtct ataccgctaa tggaagcagt tggtcggttg ataaatatga
     4201 tataaatact gggcagttgg tagaaagtat catagataca tttgaatttc ccagtttaat
     4261 tgcaactcct tacgctggaa attttgcgta cgtgttgaat ggtgagctgt ggccgaaagg
     4321 tgtaacggag attagtttgt ctccattaag caggggaggg gacttcagcc gtttatttga
     4381 aacgctgagg acgattgtat tttctctcga tagcactaga gcttattttc tagagccata
     4441 tagtgaaccg tttcttatta ataacttata cgtagttaat acggccagac agaggatcat
     4501 tgcaaacgtg tctctccccg gcgcttttga cctcgccgta acgccggaca aacagtatat
     4561 ttatgcggca cagcccaacg acaatgctgt gaccgtgtac cgcacaagtg gttatacagc
     4621 cgtgacggtg attccggttg gcgcgggtcc gtctgcgatt gcgatgtagc tattttatag
     4681 atcaagagaa gcggtgctgc gataagagaa tcgtttataa ataaatgatc cgatttgctg
     4741 aatggtagcc aggataatca gaaacagcag ttcacttata gagaaactga gcatccacca
     4801 aatcccggct gctgccagcg ctcccgcaaa cacttttctg aacaggctgc cgtgccggaa
     4861 aagctgccgc aaataagttc gcatgcaaaa caataaatac agaatcagta gcatcgcaag
     4921 tcccattgaa agggcagggg gcgtgtgaag gcggaaaggg acggctttaa cgatttcgaa
     4981 catgcagccg aatatgatga cttggcacaa cacggcagcc atcacgtatg tttggcggac
     5041 gtttttatag ctgtcacgca gcgatttgac gtcttctgca tatcggctgc acaagttgtg
     5101 ttgctgaaag tcacagcagc tttgatgaga ctgtgtgagt ttctgaaaag ctgctgtcat
     5161 gtttttcacg gattgggtga cataatgaag atatagaaaa gcaggcagca tcaggagggc
     5221 agcggtacaa gccagcagcc cgagccgcac agcatcattg ttgatcatct gtacatattg
     5281 ggcggcggct tcggcaacgg cctgaaccca tccgaaggaa taagccgcca tacctataag
     5341 cagcaataaa agggtaaaga cagtgctttt tttcattgtc tgatcgcctc tttctgagaa
     5401 acgtgaatga tcgctttgtt agaagatgcc attgcatcaa tgagagacaa gaaaacctgc
     5461 gcatccatat cttgaatgat gtggtacatg tcaagaaacg agcaatcgca cctgtcacac
     5521 tcggctgccc actcgaagca tttacgcaca taatcgctgt cataaatgat cgcgtctgtc
     5581 aaagagtcct tgccgtattg aagccaggcg gcaacctgtt ctttcttctg tgtgacatag
     5641 tatgaagcca catcgatata agctgaagaa tgggtccctt gactgtgaag gatcaagaaa
     5701 ccgccatcct catatatata agtctcggct gacaagcgat cgatttccag acggtacgtt
     5761 tgctgaatct cttgaaaaaa cggtgaatct aattgaaata gaatacgagc cgcgatatcc
     5821 caataaagct ttatcgccaa cagatcgttt tgcccgggaa gtgcgccgat ctgtaatccg
     5881 gtccatgtat cttccatccg ctcctcatca cccagcacca ttttttgtga gagggctgga
     5941 gggcatgccg ggatgatttt tctttcagca tgataatccg gacgtttttc cagctggagg
     6001 tgaggaggca aaagcgtttc tgtattttct gagcccccaa tcaaaaacag cgtcatccga
     6061 tgggcttggt aggcagcctt ataggctttt tgtaaatcac tgatgtccag cgcctcaata
     6121 tcttcgattc tgcctgcggg gaaaacggca gctggtgagg agggagaaag catgctgatc
     6181 agctgataat gatatgagag ctgatggtta aggtgtgctg tttgaatttc gcttgtaatc
     6241 acagcttttt cctgagcgac aatcttcttg tcaaatgagt ggttccataa agcatcaagc
     6301 aggatgggga tcgtttgtct gagccgatcc ggtaatgagg taaacatgaa attggtatcg
     6361 gtgtaggtag tgaatgcgtt taaaagcgcg ccatgcgcaa aaaaatcact gtacagattg
     6421 cggccgttat gccagaagag aagatgctct aaaaaatgcg ctgtgccata cggaagcagt
     6481 gtatcaccgg attctgcccg tatacataca tctcggcttc caaaatcgat ttttacattg
     6541 cacagccgca ggtgggcgcg ggggaatttc aatctgaata tttttagtcc gctgtctgtg
     6601 tatctgatat cggttcgttc atccagctgt tgaaaaaagg atttcttttc catctcttca
     6661 tccccttact acatgagctc cgatataatt gatggtcgct atgaattgca atacatcacg
     6721 gcatgtaacc gctgagatgc catccagcaa ggcttctttc gtgcaggaga agcggcgcag
     6781 gacccccata taggccaata gaccttcggg agaatcgaat tgcagcagca attcattgcg
     6841 taaaaactgc tttgcctgtt ctagttcccg ctcatctgta tgaaaagctg agacagcttc
     6901 caaaacgcgc gggggaatgt ctatctcatg aagctgatct gtacatattg aaacaagcag
     6961 caaattgttc atgacatcgt aacgggtgat aacgtgatag actgccagat ccttctctct
     7021 gaagtgcttg aataaagcgg aatggccgta ctttcccagt aatccgtcta ttagctgtat
     7081 tttgatataa tcgctggcat ctttcatctc tccgcagtca aatccgagtg tcaagacgga
     7141 aggacctgca gcgctgcgag tctctgtttc aaaaacatgc cggtttacgg gtattctttc
     7201 ggacgttata gcggacgttt gcggggcatg tccccgaaca tcacatgctt gtacttgtcc
     7261 caatatgttc agctgttttt gctgggacac taaatcaacg gtaaagtccg ttgcgtcgag
     7321 aaaccgttta ggatgaatcg cctttatcct gtctttccgg ccaaacatgc ctgtgccgta
     7381 catcgggttt ccgaagacct cctcagccaa gcgagccgcc gagtaggaga agggatcagt
     7441 gaatttcttt tcgattttca gcagcagctc attcctggcc ttttcaactg cttcgaatga
     7501 aagagaagaa gggaaagaca agtctgcaaa agttttcatc agggcgtcaa catgaagatt
     7561 cccgttatat aatgggtgaa tcaaacgggt cccgcaggtt ttcagctgct gatcaaaaaa
     7621 gagattcgct gagtacatga aacggctgcc ggcagcataa ccaaaagcat caatgatttg
     7681 ctccttcagg tatgcggcgg cgccgtaaaa ataaatcgtt tcttcctcag gttccgccgc
     7741 gctttcgatc ggtttcagaa agctcgcggc gattgaaata gttgaaaatt gatgagtctt
     7801 cagcaggtta acttccaagc cgttctcttt tgcttgtatc aaagaaacca ccatcctgtt
     7861 tttgcaggta atagactatg accagaccgg ctatcggaat gaccgccaag gatacagcgg
     7921 tgccggctaa tgtggctaag aataggggaa gacaaaacag ataagaccga tattttgaga
     7981 aaccgctcca tagctgctgc tcagtctgcc agctgaagga gggccttttt tcatccgcag
     8041 ttaacctgat aaaagctccc gccagcagca actcaatgca ctgcaaaaaa gtgagaactg
     8101 aaatcggacg gccgctgatg aaacccacaa tcatcacgac aaggagaaat ccgcctgcca
     8161 ataggcctga ataaaagcga tatttcgccc aaaacatcgt tttccgcttg atcggaagcg
     8221 tgatgagcag catccggtca tttttttcaa tcgaatacaa aagggcgatc ggcgagcaga
     8281 tgagcaaaag cgcggaaatc acgatataaa tcacttgctg attgaagatg ccggtattca
     8341 tcatctggaa cgaaaagaag ccgctgaacg ccgccattac cgcgtaattt aacagcatcg
     8401 ctttagaaga gataaatcgg ttccattctc ttttgtaaaa cgaaaattca gatcgccgca
     8461 taaatgaatg catcttgccc tgctgcggag gcgcctgcag aaagacagga aagtcaatga
     8521 tcaccgccca caggatatgg atcgcgcaaa gcggaatcgt ggcggccggc atcaaagcgg
     8581 cgctgagaca tacacaggcg aatatcgccg catgcagcag aaacatccag ttcttctttt
     8641 tgacgaagtg gttgcttagc acaactccga aaataatgga gtaaacggta aaaaacgaaa
     8701 acctgccgag ccaaaacaat gtttgcgccc ctgacagcgt tccgtttcca aataagaaca
     8761 gcggtaaaat aaaaaagaat aaagttcttc tcaaacaggt atcgacaaac aaaacgacac
     8821 tctgggcgag ccaaaagctc cgtgaagaaa tcggcagcag gcagctcagt ttcatataag
     8881 attccttcca ttgagatgtc acagaaagaa acaccatata tgcgttcatt aagagaagcg
     8941 cgagtatgat atacgttttg cgcaacaccg attcatcaat gccggcctgg cgaatcagcc
     9001 cgatttcaaa cacggccaga atgactaggc ctgcggcaat gcggatggcg tcctttttcc
     9061 cttgccggct gtaaagctgt ttgaacagca aagacataat ggggattatg ttattcatga
     9121 ccgatcacct cgaaaaattc ccgccgcaga tcggtctcct ctccaatcgg aatgaccttt
     9181 tggatctgtt tgttgtgaag aatagccgca taatcacaaa atctttgcac gacatcgagc
     9241 agatgagaag aaaacaaaat ggtcccgcct gcttcacagt actcgcgcat tttctgataa
     9301 aaaacctcta tcgattccac atccaaaccg acgagcggct catccaaaat aaacagggga
     9361 gcgcgcagca ataagcctgt catcaataca accttttgcc tgttccccaa ggaaagctcc
     9421 gaaattctcc tgttgatgta tttcgaaaaa tgaaaggcct cggccaaact ggcaaactgc
     9481 tgctctgaaa aatccttttg ataaagcgaa tggacgaaag acacatagtc cttcgccgta
     9541 atttctgtaa atagcagcgg ataatcggcg gcgaagtaac ggtgagtctt cagctgatct
     9601 gatgttttct gcggcatgcc ggcctccgct tcaattccgc acagtgtaaa gcgcccgctg
     9661 aaattgcggt tcacgcctgt cagcgtatta atcagtgtcg tttttccggc gccgtttacc
     9721 ccaagcaacc cgtaaacggc gcctttttct aaatgtaaat ccacttgttc taagatgacg
     9781 ttgtcccgtt cataccaaac ggatacatcg tgtatatcca aaatgctcat cgcgagtcag
     9841 ccttccgcgc gcgaatcccg aacagaatgg caatggcaat gaaaatcagc gtaaacagat
     9901 agtcgctttt gacaaaatag acgactgcgc cgatgacaaa gataaatgaa aggatataca
     9961 gtaaaattct tctttgtgct ggtgacaaat cgtttccctc ctaaataagc tggaccacgt
    10021 cttctaattg ttcatttttc gcccaagagc aaatgttttt tcggtgatat ttgttagagt
    10081 tcagcccttt taagtaacag cctccgcaat agccgctgaa cgggcatttg tctttcatgc
    10141 aatgttcact gaaccgcggc gcctgcgctt gccacagttt atggacgaga ggggagttaa
    10201 agatgctttc ataggaatca tgaaaaatat ttcccaatga aaattccttt ggaaagaggg
    10261 cgcaaggacg tacttcgccg aacgggctga tcacaatgga cttccagcca gcgccgcaat
    10321 ttgccgcgcg ttttctctca tagggaataa tcggaatcag atctttaaac tcatcaatca
    10381 cattttgctc gtattccata aacttgcggt gctgctcggc gtctttcgtt ggatgggcaa
    10441 tatccctgcc tcttccgaaa tcgtcaaccc aattgtaaga aaatgccttc gccccgagat
    10501 cccgaacctt ttgggccata tcgtggattt cccacatgtt tttttcgaag acagacatgg
    10561 cgactctgac aaatataccg tggtcactca acaattttat cgttttacaa gtttgggcaa
    10621 aagagccttt tctccctcta aaggagtcat ggacctcgga attgacacta tcaagagaaa
    10681 tgccgacgat gattttttgc ttgtaagtct tcaaaagctc caggctctct tttcgcatga
    10741 gtgttccgtt tgttaagaca gcgacttttt tgaacttttt acacacatag tcaagaatct
    10801 cattggcgtt tggatggaca aaaatttctc cgcctgtgat ttcgcatgtc aatacaccgt
    10861 tatcaaacag catatcagcc gtttttttga attgctcaat cgacacggtg ccgagcgctt
    10921 caggtgagct ttccaaataa cagtgggcgc atttcaaatt acagcggtgc gtcagttcaa
    10981 aggtggcgtg caggggcatc ggaaattcat tgctgccgct cgtggtgatt gtatggcggc
    11041 tggcccggtt tccaagctgg atcacctgct tgttctggag catgttaagc atgtcgtaat
    11101 accaatcttt atggtcttcc ggtgattcat catacactgc acattgctca gctaaaatct
    11161 gctcagctgt tttttggcca tccatgcgca tgcagagctc gtaagccgtt ttgttgagat
    11221 ccaaatactc aaagtcagaa atggagacat tatcgcgcaa gtagtcgatt tctaacacgc
    11281 cgccctcagg aagctggtga actcttacac tttcattaat aaatggaaac atctgctcta
    11341 taaacaaaat accatcccct atacatatga ttcaaatgaa aaacggttgt gtatgtatat
    11401 ccaagaggta gattttagtt aaaaattgta atttacttaa aaagggcata gtagaatgac
    11461 tatgcccttt tgggagatcc ttacccccat agaccgaata gacctgttgc accggcaatt
    11521 tcaaaatcag ggataggacc gtccactaga caagcggctc cgatcgagca tgttgcacaa
    11581 cctttgtttt ctacaatgac agcttttttc ataattgaat cctccctttt tttgtttttc
    11641 tagcagatct atgttgtact tttatcttaa aactatcaaa ttactaattc aatacatata
    11701 ttttgaaaaa aatgtgaaaa ggaaatgata gatttcggaa aaatgtaaca tttcctaaag
    11761 gtaattagtg atatgatttt ctcttctata taaggaaatg ctttttatga ggtttatctt
    11821 caaatctgat gagcaatgat ggtaagatag aagcagttga agtttacaaa ccgaatgatt
    11881 atactattca agtcaaagtg gaatgatgaa aaggacgtgt cagaatgaag caagagacac
    11941 cgataacact ccatgtgaag tctgtgatcg aggatgacgg aaaccaagaa gtcatcgaat
    12001 tccgcaccac cggattttac tatgtaaaac aaaataaagt gtatctatct tattatgaag
    12061 aacacgactt aggcaaagtc aaaacgattg tgaaagtaag cgaaggcgaa gtcctggtca
    12121 tgaggtcagg ggctgtcaaa atgaatcagc gtttcataac gggagcttcc acaattgcta
    12181 aatataaaat gtcatttggt gagcttgagc tgaaaacaag cacaaaatcg attcaatctg
    12241 atctcgatga agaaaaaggc cgtatcagca tcgcatatga catgcatgtc ggagacgagc
    12301 aggagcattt acataatatg acgatcacgt atgagggagg aactcacgca tgaacattgc
    12361 ggaacaaatg aaggacgtgc tgaaagaaga aatcaaagcg gccgttctga aagcgggact
    12421 ggctgaagaa agccagattc ccaatgttgt tttagaaaca ccgaaagata aaacacacgg
    12481 cgactactca acgaatatgg cgatgcagtt ggcaagagtg gcaaaaaaag cgccgcgtca
    12541 aatcgctgaa gagattgtcg ctcattttga taaaggaaag gcttcgattg aaaaactgga
    12601 tatcgccggc ccgggtttta tcaatttcta tatgaacaat caatatttaa caaagctgat
    12661 tccgtctgta ctggaagcgg gggaagcata cggggaaaca aacatcggaa acggtgaacg
    12721 agttcaggta gaattcgtat cagcgaatcc gacgggagac cttcacctcg ggcatgcgcg
    12781 cggggcggct gtcggcgatt ccttgtgcaa cgtgctttca aaagcgggtt acgatgtaag
    12841 ccgcgaatac tacattaacg atgcgggaaa ccaaatcaac aatctggcgc tttctgttga
    12901 agtccgttac tttgaagcac tcggattgga aaaaccgatg ccggaggatg gctaccgcgg
    12961 cgaggatatc attgcgatcg gaaagcgtct cgctgaggaa tacggtgatc gtttcgttaa
    13021 cgaagaggaa agtgaacgcc tcgagttttt ccgtgaatac ggcctgaaat acgagctgga
    13081 aaagctgcgc aaggacttgg aaaacttccg tgtgccgttt gatgtgtggt attcagaaac
    13141 ttcactgtac caaaatggaa aaattgacaa ggcgcttgaa gcgctccgcg aaaaaggcca
    13201 tgtctatgaa gaagacggcg cgacttggtt ccgttccacg actttcggcg atgataaaga
    13261 ccgcgtattg atcaagaagg acggcacgta cacgtacctt cttcctgata tcgcgtatca
    13321 taaggacaag cttgaccgcg gctttgataa gctgatcaac gtttggggcg ccgatcacca
    13381 cggctacatc ccgcgtatga aagcggcaat tgaagcgctg ggctatgaaa aaggaacgct
    13441 tgaagtagaa atcattcagc tcgttcatct ttacaaaaac ggcgagaaaa tgaaaatgag
    13501 caaacggacc ggtaaagccg taacgatgcg tgacctgatt gaagaagtcg gcttggatgc
    13561 cgttcgttac ttctttgcga tgcgaagtgc ggacacccat atggattttg acttagatct
    13621 tgctgtatca acatctaacg aaaaccctgt gtattatgca caatacgcgc atgcccgtat
    13681 ttgcagcatg cttcgccaag gggaagagca gggacttaaa ccggcggcag atcttgattt
    13741 cagccatatt caatcagaaa aagaatacga tctgctgaaa acgatcggcg gcttcccaga
    13801 ggcagtggcg gaagcagcgg aaaaacgaat tccgcaccgt gtcacaaact atatttatga
    13861 tctggcttct gctctgcaca gcttctacaa cgcagagaaa gtcatcgacc ctgaaaatga
    13921 agagaaaagc cgcgcgcgcc tggctttaat gaaggcaacg caaattacgc tgaacaatgc
    13981 gcttcagctg atcggcgtat cggctccgga aaaaatgtaa tcacgatcaa aaggacaaag
    14041 tcttcgggct ttgtcctttt tttatgagaa aaacgtgtga tgtaattcac aatcctgttt
    14101 gccgagtttt tgtatgataa gactgattat tgaatcattg aaaggggcaa gccaaatgat
    14161 caaccgtcaa cacattcaat tatcgttaca gtcattaagc ttggtggcag ggtttatggt
    14221 ttgggtgctg atttcatcac tcatttccca aatcacatta gatattcatt taagcaaggg
    14281 tgagatttct ttggtgacgg caattcctgt gatcctcggg tcgcttctcc gcattccttt
    14341 agggtattta acgaacaggt ttggcgcgcg gctcatgttt atggtcagct tcatcctgct
    14401 tttatttcct gtattttgga tcagtatcgc ggattctctg tttgatttaa tcgcaggcgg
    14461 ctttttctta gggatcgggg gagcggtgtt ttccattgga gtgacctccc tcccgaaata
    14521 ttatccgaaa gaaaagcacg gtgtcgtcaa tgggatttac ggtgcaggaa atatcgggac
    14581 agccgttacg acatttgcag cgccggttat cgctcaagcc gtcggttgga aatcaaccgt
    14641 gcagatgtat ctgattttgc tggctgtctt tgccttactg cacgtattgt ttggcgacag
    14701 gcatgagaag aaggtcaaag tttctgttaa gactcaaatc aaagccgttt accgaaatca
    14761 tgtgctatgg tttctgagcc tgttttattt tattacgttc ggtgcctttg tcgccttcac
    14821 tatctatctg ccgaactttc tggtggagca ttttgggctg aatcctgcag atgccggctt
    14881 gcggacggct ggctttattg cggtttctac gctgctcagg cctgcaggcg gattcctggc
    14941 tgataaaatg agcccgctcc gcatcttgat gtttgttttt gccgggctta cattatcagg
    15001 cattatccta tcgttctcgc cgacaatcgg cctttatacg tttggatcat taaccgtggc
    15061 cgtctgctca ggcataggaa acgggactgt ttttaaactg gtgcctttct atttttcgaa
    15121 gcaagcgggg attgccaatg ggattgtgtc tgccatgggc ggattaggcg gcttttttcc
    15181 tccgctcata ttggcgagtg tgtttcaggc aacaggccag tacgcgatcg ggtttatggc
    15241 gctttcagag gtggcgttag ccagctttgt ccttgtcata tggatgtatt ggcagcaaag
    15301 aatgaaaaca cacacggaga gaaacagcca gagcatcaac taacactggg gcattcacaa
    15361 gattgttagt tttttctcga tgggtacaaa tcaattcacg ttacaataaa cacacaacgt
    15421 gactttcttc gaggtgagct catgaatttt ctctctgttc gaccatctga tagtgatctt
    15481 atatccagcg atctgcatga attgctggaa tcgatcagca cgaaaagaaa aatggaaaaa
    15541 cacacgtatt tgtttcggga aggaatggat gcagaagagc tttatctgat tcaatcagga
    15601 ctcattgaaa tcggcaagct gacatctgat ggaaaagacc tgacgcttag aatctgccaa
    15661 aagcatgata tcgtcggaga attaacactt ttcactgaag aaccaaggta tatgctcagt
    15721 gcaaaagtgc tagaggatgg cgaggtgctc gtcattaata aaaataagct ggaaaaagaa
    15781 ttaatccaaa acggcgcttt gacatttgag ttcatgaaat ggatgagcac gcacctccgg
    15841 aagattcagt ccaaaatcag ggatctgctt cttcatggca aaaagggggc gctctattcc
    15901 acccttatcc gtttatcaaa cagctacgga gtggagcgaa gcgacggcat tctgattaac
    15961 attgtcctga caaatcagga tttggcaaag ttttgcgcgg ctgcacgtga aagcgtcaat
    16021 cgtatgctcg gagatctccg caaaaaaggg gttatttcga tagacgaatc cggaaaaatt
    16081 attttacaca agcgggacta tttacgatgt gagattgagt gtgaaaattg cccgctggag
    16141 atttgcaata ttgactgaaa aaaacaagga cagcggtgtc cttgtttttt taccttgtga
    16201 taaacaggca catgacggca agaaagaagc aggcattcac aatttccaga atgccaatcg
    16261 tttttacggg ccaatccctt ccatgaaaaa accatgcccg caagctgctc gggataaaag
    16321 cgagaaacga ccatcctgct ccgaaaagag cggataaaaa ggggagcagc aggtgatatc
    16381 cccatgacca gtatgcaaat gtcctgtttt ttctttcacg aatcaccgat ttcacataaa
    16441 aggaactccc gataaaaaat aaagcagact gcaagaaaat aaaccaagcc cagccgtcaa
    16501 gggttcccat ccccagccag cagctcgcaa acccgcccga acaaaagaac aagacacctg
    16561 caacatcatt caataaggct cgttcgtttt ttctgcgggc aaaatacata tgtatgagaa
    16621 acagcggcag taaagaaacg cccacccaga tgagaggcgg cttatgaaag accgagatca
    16681 tcaaaaagca gcaggcggga aaaccgtaat aacacatcca cttttgatat ggtttgcttt
    16741 gtttcttttt taaggcaagc gtaacgggat aaaccgctaa gtataggaaa agccagccta
    16801 ggaagagcgg aatatgccaa ataacggggc ctcccttgac catgccgagt aaaaatggga
    16861 tcagcagcat cgcccacgcg ccgtgctgct tcggaatcag cgccttcatc gaaatcctcc
    16921 ttttttcttt cattataaat gcagtcaccc tcctgataag tgacattcat catacaggct
    16981 gtgaaataca tcactgctgt acaggctcga tcgagctaca ctaaagctat ccttagcaca
    17041 ggaggttttc ctatgaatca gtgtgactat ttattatttc tgaaacaact tcctatgttt
    17101 aatgaagtgc ctctatccat tgtcgaaacc ttgctgaaaa acggcacgtt tatccgcggc
    17161 tcatgtgatc agtctccatc ttttcttcat tctcaatctg tttatattgt attaaaaggc
    17221 agtgtccgtt tcatggacac aaggctccct gaagggtcga aaaccgttgc gctgtgggaa
    17281 aaaggcgatg tgtttccgat tgatgaaaaa ggcgggcttt atttatcgcc ctttatctca
    17341 gtcaatgcca cttcagacat tctgattctc aacatcccat attacatatt taagaaaatg
    17401 atgtcttatc atccgcagct gcaaatgaac tttttggcta tgcttcagca aaatgttttt
    17461 tgttcctatc aattattttt gcggtatctg catacatcac aggatgaaaa cgctgagccc
    17521 ggttcttaaa tagagccggt ttttttgtct ttgaatgaaa ggcagctaat gacccaagcg
    17581 ttctgcctga acgcagcctt cctcacatcc tgtgaaaagc cttccttctc ctttgtgtga
    17641 acattttgtg aaaaaagcag agtgtgtgac atagttcaca aggaaacacg ctgtctctgt
    17701 ttatagtgaa cttagcatca cctgactcgg aaggagtgaa ctctcatgaa gaaaaagaaa
    17761 aggagtccgt tgtttaggag attgaattat ttctctccta tcgaacacca ttcaaataaa
    17821 catagccaaa ccacccgcga agatcgcgat tgggagaatg tatacagaaa cagatggcag
    17881 tacgacaaag tcgttcgctc cacccacggt gttaactgta cagggtcttg cagctggaat
    17941 atttatgtga aaaacggaat tgtcacgtgg gaagggcaaa atttgaatta tccatcaaca
    18001 ggcccggata tgcctgattt tgaaccgaga ggctgcccgc ggggggccag tttttcatgg
    18061 tatatctaca gcccgctgcg tgtgaaatat ccatacgtgc gcggtgtact gattaattta
    18121 tggcgggagg cactgcaaga acatcaaaat ccattggaag cctggaaatc gatcgtcgaa
    18181 aaccctgaaa aagcgaagtc ctataaacag gcgagaggga aaggcggttt tgtgcgcgct
    18241 gaatggccgg aggtgctgaa gctgatttca gcctctctgc tgtatacagt gatgaaatac
    18301 gggcctgaca gaaacgtcgg tttttctccg attccggcca tgtccatgat cagccatgca
    18361 tcaggctccc ggtttatgtc gttaatcgga ggccctatgc tcagttttta tgactggtat
    18421 gcggatcttc ctccggcatc cccgcaaatt tggggtgacc agacggacgt tccggaaagc
    18481 agtgattggt acaattccgg ctatatcatc acatggggct ccaacgttcc gttaacgaga
    18541 acgcctgacg cgcatttttt ggcggaggcc cgctataaag gcgctaaggt catttcgatc
    18601 agtccagatt ttgcggaatc ctcaaagttc gcggatgact ggctgagtat tcgccaaggg
    18661 actgacgggg cgcttgcgat ggcgatgggt cacgttattc tgcaggaatt ttacgtgaac
    18721 caagaaactg aacgttttat tgagtacgcg aagcaataca ctgattttcc atttctcgtc
    18781 actctgtcaa aagaaaatgg cgtatacaca gcgggacggt ttctgcatgc gaaggacatc
    18841 gggcggaaga caaagcatga tcagtggaag cctgcggttt gggatgaaca gacaagttca
    18901 tttgccatac cccaagggac aatgggctcg cgctgggacg ggcagcagaa atggaacctg
    18961 cacatgattg atgaagaaac cggggaaccg attgaacccc gtctctctgt gctcggaata
    19021 gaggatgaaa tcggcacggt gcgcattcct tatttttcaa atgacggaaa caaagtgctc
    19081 gagcgggatc ttcctattaa aaaaatgaac ctgaacggtg aagagacgta cgtcacgacc
    19141 gtgtttgact tgatactggc taactacggc gtaaatcggg gcatcggcga acaacaagct
    19201 gtctcctatg atgatcctga gccgtttacg cctgcctggc aggaacaaat gacaggaatc
    19261 aaaaaagaag ctgtcgttaa gattgccaga gagtttgctc aaaatgcgat cgatacagac
    19321 ggccggtcta tgattatcgt aggagccggc attaaccact ggttcaactc cgacacgatc
    19381 taccgagcag tgttaaatct tgttttgctt gtaggcgccc aaggcgtaaa tggcggaggc
    19441 tgggcccatt acgtcgggca ggaaaagctc cgacctgctg aaggatggca gacgattgca
    19501 actgcaaagg actgggaggg cgtgcccaag ctgcaaaacg gcacttcatt tttctacttt
    19561 gcgacagatc agtggcgtta tgaggaccag ccgatcagtg atttggcatc accgattgct
    19621 gcgtcatccc gctacaagca ccacgctgat tacaatgtgc tggcggcgcg gctagggtgg
    19681 cttccgtctt acccgacttt caatcaaaat ggcatcgatc tgtataaaga agctgaaaaa
    19741 gcaggggcag caacacctga agacgtaggt gcgtacgtgg cctcacagct ccaagagaaa
    19801 aaactgaaat tcgcgattga agatcctgac aatgaagtga atttcccaag gaatctcttt
    19861 gtatggcggg caaatctgat ctcaagctca ggaaaagggc atgaatattt tctcaagcat
    19921 ttgctgggga caacgaacgg tttaatgaat gacgacagcg acagcatccg ccctgaagaa
    19981 atcaaatggc gggagcaggc gccggaagga aagctcgact tattaatcaa tcttgatttt
    20041 cgaatggcgg gtacggcgct gtattccgat atcgtgctgc cggcggcgac atggtatgaa
    20101 aaacacgatc tcagcagcac agatatgcat ccgttcattc atccatttgc tccggcgatc
    20161 tcagctccgt gggaatcgaa gtcagactgg gatattttca aggcgctgtc aaaagccgtt
    20221 tccgatctgg cagaagaagt caatatggag ccggtgaaag aagtggttgc gacgccgctc
    20281 ctccacgaca ccatgcagga attggcccag ccattcggca aaatcaatga ctggagcaag
    20341 ggcgaatgtg aagccattcc gggaaaaacg atgccgaaca tccaagtcgt tgaacgggat
    20401 tacaaacaca tttttcataa aatgaccgca ctcggtccta acgctgcttt aaagccgagc
    20461 ggaacaaaag ggatgagctg gtcaatagcc gatgaatatg aatcactcaa aaagagactg
    20521 ggagaaatca cctcagacag cgtggcaaag ggatgtccaa atataagtga agcaaagcag
    20581 gcggcagaag cggttttaac cctatcatcc acttcgaatg gaaaggtcgc cgtaaaagca
    20641 tgggaatcac ttgaaaacat cacaaacctg aagctgaaag acctggcgga agagcgcgag
    20701 gaagaatgct ttacgttcga acaaattaca gcccagccga aaacggttat cacgtctccg
    20761 gcatttaccg gctctgaaaa aggaggccgc aggtattcgc cgtttacgac gaatgttgaa
    20821 aaattaatcc cgtggcggac actgacaggc agacaatcct attatgtcga tcatgaactg
    20881 atgatggaat tcggtgaaac gatggcgaca tttaaaccga tcctccagca ccgcccgttt
    20941 ctaagcaagc ggcctgatca agagggaaaa gaaatcgtcc ttaattattt gacgccgcat
    21001 aacaaatggt ccgtccacag catgtatttt gattccctgc cgatgctgac gctgttccgc
    21061 ggcgggccga ccgtatggat gaataaagat gatgcagagg atacggatat caaagacaac
    21121 gattggattg aatgcttcaa ccgaaatggc gtagtcgtcg cgagagccgt tttgtctcat
    21181 cggattccta aaggaatggc gtttatgcac catgcccagg accgccacat caacgtgccc
    21241 ggcacgaaac tgacaaataa ccgcggaggc acccataaca gcccgacaag gattcacgtc
    21301 aagccgacac agatgatcgg gggctacgcc cagctcagct acggctttaa ctattacggc
    21361 ccaacgggga atcagcgcga cctgaatgtc gtcatccgca agctgaagga ggtcgattgg
    21421 cttgaagatt aaagcgcaaa tcggtatggt catgaacttg gataaatgca tcggctgcca
    21481 cacgtgcagc gtcacctgta aaaacacatg gacaaaccgt accggtgcgg aatatatgta
    21541 cttcaataat gtagaaacaa agccgggcat cggctacccg aagcaatggg aggaccagga
    21601 caaatataaa gg
//
