LOCUS       c00034_JAGFPW0..       13871 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAGFPW010000004.1 Bacillus subtilis strain S1 4, whole genome
            shotgun sequence.
ACCESSION   JAGFPW010000004
VERSION     JAGFPW010000004
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-21 03:14:16
            Original ID  :: JAGFPW010000004.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 129232
            Orig. end    :: 143103
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13871
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[134232:138103]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8871
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..13871
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13871
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(385..1722)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 303.6; E-value:
                     3.2e-92)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg34_133"
                     /transl_table=11
                     /translation="MEQKVKDDIQRVFQLQKKQQKALRASTAEQRKEKLQRFLDSVIAH
                     EEEIIEAIRKDVRKPYHEVKKAEIEGTKKAIRDNMNNLEQWMAPKEVGSSLSPEANGIL
                     MYEPKGVTLILGPWNYPFMLTMAPLAASLAAGNSAIVKLSDFTMNTSNIAAKVIRDAFD
                     EKEVAIFEGEVEVATELLDQPFDHIFFTGSTNVGKIVMTAAAKHLASVTLELGGKSPTI
                     IDSEYDLMDAAKKIAVGKFVNAGQTCIAPDYLFIKKDVQDRFAGILQTVVNAGFMEDDH
                     TPDRNKFTQIVNDRNFNRVKDLFDDAIEKGAEVVFGGVFDASDRTISPTVLKNVTPDMK
                     IMQEEIFAPILPMMNYEDIDEVIDYVNDRDKPLALYVFSKNQDLIDNVLQHTTSGNAAI
                     NDVVVHFSDVNLPFGGVNTSGIGSYHGVYGFKEFSHEKGVFIQASK"
     CDS             1865..3007
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 42.6; E-value: 1.4e-12)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg34_134"
                     /transl_table=11
                     /translation="VPESAEAQVKQALLALLEERDMQHITMKEIAERAKVSRGTLYLYY
                     EDKFSIIEDLIEDMKEGLGKALFDAFSHLDTLHLNKKRQTVHPTLSFVHEHRSFFSVMM
                     NRGHFHRFFKDVFQQDVLLTPVHVNLTPIEREIYGHYRALYTYAIILYWLNEDAAATPE
                     AISQKVWELVSQKRFYWLFGQAVPGEREKGKPIDRRVVRTREALQQAFLDVLAEKQDYA
                     GITISDITRKSNIRRATFYDHYANKEELLQTMIQRSCAEIIDHLTIASSPNELSFEEAV
                     EALAGLLSALDRMPIVHLLNRDWVVPHVIPELLKALESFYLHQQTNIPAEKKLYAYYVS
                     AMIIGLILYRLDEGKAHAPEVLARKFLQFLDVKKYKVVLL"
     CDS             complement(3525..5000)
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 65.8; E-value:
                     5.3e-20)"
                     /gene_kind="transport"
                     /locus_tag="ctg34_135"
                     /transl_table=11
                     /translation="MKRNFFNLHDLKDSREFYESKPKPIGVFFTYILIALLIACIVFSF
                     YGKKEVILKTTADIQYTKPNSNVTNEVAGKVKTVDIKQVDKVKKGDTLLTLDNTEIQAQ
                     KKAVKADIKDLKEQAALNKTLKKSIENDKNLFSEDDHWGYQDQYLSYEKQSILLESSKE
                     NAKTQQKKLKKQKESIKDSLDKTKNKVKLKLQRISDLQDSIKNNKSFAKQDDKYSSYYN
                     SYQTNKQNVEQQLDDLRKMKDELDKNRFSQQKENLNGQLESLKQDMLVKLSEEKDELNQ
                     SLDEINSSIKSDDSDSDSDNSEETNYKLSIEQLKTNLLNQTSQKQTDLQTTLKSKEDDL
                     KMIDLQLEKYKIKAASDGYVNVLTNISPGDNLQAGTAILTIIPDKEKLKANIYIPSHEI
                     TNINEKEKDEVRFHIENTNQTIKGVITKISPDSISDQNGQKFYIAESTIEKNKVMNDNG
                     STLHLKNGMQTDVSIIVDSKRYIDYLLEILHLQ"
     CDS             complement(5001..7184)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 304.3; E-value:
                     2.9e-92)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_136"
                     /sec_met_domain="TIGR01193 (E-value: 1.1e-238, bitscore:
                     788.0, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 4.7e-44, bitscore:
                     143.3, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFFNRYHCVRQLDQKDCGAACLSTIAKHYGSKLSLAYIRDIAGTD
                     TQGTSALGMVKAAEQLGFSAKAVRAEHTAFDQSITLPAIAHIIIDQQLLHYVVIHKISK
                     DKIIIADPGKGLVTYQKDDFFKIWTGILILLAPTETYKKQTETSNISADIFRLILQQKS
                     LIIHTFLASFIITIFGILGTFYFQTIIDQILPNGLSNTLHILSIGLLIMYLFKVFLIGF
                     RQYLMILLGQKLSISIMFGYFQHVLTLPMKFFSNRKVGEIISRFTDANKVIDAVVSASL
                     SVILDTIMLIMVGIFLYLQNTTLFLITLAFIPFYILTVWIFIKPYENINNTEMENNAQL
                     TSKIVETLNGIETVKAYNAEYMMSFETEKRFVKYLRSAFKHGVIDNLQSSIKMFLDLAS
                     GALILWIGSTQVMKGTLTIGQLITYNALLTYFLNPLQNIIGLQSKLQSASVASKRLGEI
                     LKLEPELKEKEAQITSTSSITGPLSFNKINFRYGTRRLILKDITLHIQKGEKVAFVGES
                     GSGKSTLTKLLMKFYTAESGEVLINGYHINDIHTNALRESISYIPQESHFIQGSILENL
                     LLGNSGSFTFEEIIEVCKQTNVHDFVNDLPMRYDTLVEENGSNLSGGQKQRLAIARALL
                     RKPNILIMDESTSNLDTTTEQGISNMIYDQTDDVTTIIIAHRLSTIMNCDKIFVMENGE
                     IIEYGNHNDLLKNKGKYYELWENQMPSREMVTI"
     CDS             complement(7280..7432)
                     /locus_tag="ctg34_137"
                     /transl_table=11
                     /translation="MKLFYSYIIAGGLFCISLSYFFHLGVFNLALYLIYINYAFILYKR
                     AKSSK"
     CDS             7577..7795
                     /locus_tag="ctg34_138"
                     /transl_table=11
                     /translation="MNNNLKLERTRANLTQEQLAEKIGVTRQTIGLIEKGKYNPSLQLC
                     LKICIELKVTLNDVFWTYNREEESNEG"
     CDS             7785..8210
                     /locus_tag="ctg34_139"
                     /transl_table=11
                     /translation="MKDERISHIENKIGHESFLLVIALVFVSFILSIMFKIPSTLMTII
                     ILFVGSGYYGLRAMSKGILRVNLKKKKKSSYFLLIVFTFILYMATSILFKIITFPFTTK
                     EFLFQILMYILWLIPFSLIMYTTYKFSNRQQKKELEN"
     CDS             8399..8629
                     /locus_tag="ctg34_140"
                     /transl_table=11
                     /translation="MDTKSIKDVELQALTLEEAEQIDGGSYAKYLGTSVVTGAGAGVVG
                     GVPGVILGAHAGAIAGSVGYLGGSLIAGKWL"
     CDS             8647..8871
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_141"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 3e-09, bitscore:
                     31.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENNNRFSELNVKEMEQIDGGGWRSALGGAFSGALVGASTVGVGG
                     AAVGGPVGGVGGAITGGIVGGIVGGINEW"
     CDS             complement(8986..9729)
                     /NRPS_PKS="Domain: PKS_KR (7-118). E-value: 3.5e-08. Score:
                     25.3. Matches aSDomain: nrpspksdomains_ctg34_142_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     133.6; E-value: 1.4e-40)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg34_142"
                     /transl_table=11
                     /translation="MGRLENKTAVITGAATGIGQATAEVFANEGARVMIGDINEDQMKE
                     TVEAIRQNGGQADAFHLDVSDENSVKAFADQIKEACGTIDILFNNAGVDQEGGKVHEYP
                     VDLFDRIIAVDLRGTFLCSKYLIPLMLEKGGITNLTKAMAIDYARDGIRVNSISPGTIE
                     TPLIDKLAGTKEQEMGEKFREANKWVTPLGRLGQPKEMATVALFLASDDSSYVTGEDIT
                     ADGGIMAYTWPGKMLLDEKWKEETK"
     aSDomain        complement(9376..9708)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg34_142_PKS_KR.1"
                     /evalue="3.50E-08"
                     /label="ctg34_142_PKS_KR.1"
                     /locus_tag="ctg34_142"
                     /protein_end="118"
                     /protein_start="7"
                     /score="25.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TAVITGAATGIGQATAEVFANEGARVMIGDINEDQMKETVEAIRQ
                     NGGQADAFHLDVSDENSVKAFADQIKEACGTIDILFNNAGVDQEGGKVHEYPVDLFDRI
                     IAVDLRG"
     aSModule        9376..9708
                     /domains="nrpspksdomains_ctg34_142_PKS_KR.1"
                     /incomplete
                     /locus_tags="ctg34_142"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(9634..9702)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg34_142_0001"
                     /evalue="6.70E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg34_142"
                     /protein_end="32"
                     /protein_start="9"
                     /score="15.6"
                     /tool="antismash"
                     /translation="VITGAATGIGQATAEVFANEGAR"
     CDS             10259..12139
                     /locus_tag="ctg34_143"
                     /transl_table=11
                     /translation="VAKKEFKAESKRLLDMMINSIYTQKEIFLRELISNSSDAIDKIYY
                     KALTDDALTFDKDSYYIKVAADKDARTLTISDTGIGMTKDELEQHLGTIAKSGSLAFKK
                     ENELKDGHDIIGQFGVGFYAAFMVADVVTVISKALGSEEAYKWESAGADGYTIEPCEKD
                     SVGTDIILKIKENTEDDSYDEFLEEYRLKAIIKKYSDFIRYPIKMDTTINKPKEGSENE
                     FEEVQEEQTVNSMVPIWRKNKSELTDEDYEKFYAEKHYGFDKPLTHVHISVDGAVRYNA
                     ILFVPENMPFDYYSKEYEKGLELYSNGVLIMNKCADLLPDHFSFVKGMVDSEDLSLNIS
                     REMLQHDRQLKLIAKNISKKIKSELQSLLKKDREKYETFYKSFGRQLKFGVYNDFGANK
                     DQLKDLLLFYSSKEKKLVSLDEYVSRMPEEQKFIYYATGDSYDRIEKLPQTEMVADKGY
                     EILYFTEDIDEFAIKMLASYQEKEFKSVSSGDLGIDTDEDQKQSEEEESKYKDLFEEMK
                     NILSDKVKNVRISKRLKSHPVCLAADGEVTIEMEKILNAMPDSQNVKAEKVLEINPNHE
                     VFQTLQDAFEQDKEKLSLYTNLLYNQALLIEGLPIQDPVEFTNNICKVMV"
     CDS             complement(12181..13566)
                     /gene_functions="transport (smcogs) SMCOG1169:sugar
                     transport protein (Score: 436.6; E-value: 1.6e-132)"
                     /gene_kind="transport"
                     /locus_tag="ctg34_144"
                     /transl_table=11
                     /translation="VKKDTRKYMIYFFGALGGLLYGYDTGVISGALLFINNDIPLTTLT
                     EGLVVSMLLLGAIFGSALSGTCSDRWGRRKVVFVLSIIFIIGALACAFSQTIGMLIASR
                     VMLGLAVGGSTALVPVYLSEMAPTKIRGTLGTMNNLMIVTGILLAYIVTYLFTPFEAWR
                     WMVGLAAVPAVLLLIGIAFMPESPRWLVKRGREEEARRIMNITHDPKDIEMELAEMKQG
                     EAEKKETTLSVLKAKWIRPMLLIGVGLAIFQQAVGINTVIYYAPTIFTKAGLGTSASAL
                     GTMGIGILNVIMCITAMILIDRVGRKKLLIWGSVGITLSLAALSGVLLTLGLSASTAWM
                     TVVFLGVYIVFYQATWGPVVWVLMPELFPSKARGAATGFTTLVLSAANLIVSLVFPLML
                     SAMGIAWVFMVFSVICLLSFFFAFYMVPETKGKSLEEIEASLKKRFKKKKSTQNQVLNE
                     RTL"
ORIGIN
        1 agaatagcga aaataaatat gatggccaaa acagggattg tgccaatgat caacatgaaa
       61 aactcatatt gggcttctga catgtgtgta cctgctgcat caatgagtgg caacacaatg
      121 aaggtgttaa tgaaaatcat aatgaaagag aatatagcta taataaatac atcaataata
      181 gaggcggctg cccgaatcca aaatcctgct ggtttttcca tgtatcattt tactccttta
      241 aagttttctg ggtattatac gttaggggct gcagggtttg gtctcgtagt aaaaatggta
      301 ttttatcact tttaatctct ttatttaggt gatataaaga taaaaaaaga acctgcaaga
      361 tgatgcagat tctcttcgtt acaattattt ggaggcttga ataaatacac ccttttcgtg
      421 agaaaactct ttgaatccgt ataccccatg ataggagccg attccgcttg tgttgacgcc
      481 gccgaatggc aggttgacgt cactgaaatg gacgacgaca tcattgatgg cggcatttcc
      541 tgatgtcgtg tgctgaagga cgttgtcaat caggtcttgg tttttgctga acacataaag
      601 tgcaagcggt ttatcgcggt catttacgta atcgatgacc tcgtcgatgt cttcatagtt
      661 catcattggc aggatcggtg cgaagatttc ctcctgcatg attttcatgt caggcgtgac
      721 gtttttcaaa acggttggcg agatcgtgcg gtcgctggca tcgaatacgc cgccgaacac
      781 cacttccgct cctttttcga tggcatcgtc gaacagatct ttgacgcggt tgaagttgcg
      841 gtcattgacg atctgcgtaa atttgttgcg gtctggggta tgatcatcct ccataaatcc
      901 agcgttgacg actgtttgta aaatccccgc gaacctgtcc tgaacgtctt ttttaatgaa
      961 caggtaatca ggtgcgatgc aggtttggcc agcgtttacg aatttcccga cggcgatctt
     1021 tttcgctgcg tccatcagat cgtattcact gtcaataatc gtcgggctct tgccgccaag
     1081 ctcaagtgtg acagatgcca agtgtttggc agccgctgtc atgacgattt tcccgacatt
     1141 tgtgcttcca gtgaagaaaa tatggtcgaa cggctgatca agtagttcgg ttgccacctc
     1201 aacctctcct tcaaaaatcg cgacttcttt ttcatcaaaa gcgtctctta tcactttagc
     1261 ggcaatgttg ctcgtgttca tcgtgaaatc ggacagcttc acaatcgcgc tgtttccggc
     1321 tgcgagagaa gcggcaagcg gcgccatcgt cagcataaac ggatagttcc acgggccgag
     1381 gatgagtgtg acgcctttag gctcgtacat aagaatcccg tttgcctcag ggcttaacga
     1441 tgaaccgact tccttaggcg ccatccattg ttccaggttg ttcatattat ctctgatcgc
     1501 ttttttcgtt ccttcgattt ccgctttttt gacctcgtga tatggtttgc ggacgtcttt
     1561 gcggatcgct tcaatgattt cttcctcatg ggcgatgacg gaatctaaaa agcgctgaag
     1621 cttctctttg cgctgttccg ctgttgaagc acgcaaggct ttttgctgtt ttttctgaag
     1681 ctgaaagaca cgctggatgt cgtcctttac tttctgttcc attgtaagat ccccctcatt
     1741 tgctttcttc ttttctcgga cctattataa ggtggtacct tttttataag aaagacaacg
     1801 gtgaaccatc tatacgttac cgtacatata ttgaacaact gtctaatgat tggaggtgtc
     1861 ttttgtgccg gaatctgccg aagctcaagt gaaacaggcg ctgctggctt tattggaaga
     1921 aagagatatg caacatatca caatgaaaga aatcgctgaa agggccaaag tgagccgtgg
     1981 gacgctctac ctttattatg aggataagtt ttcaatcatt gaggatttaa tcgaagacat
     2041 gaaggaaggg ctgggtaaag cgctttttga tgctttcagt catttggata ccctccactt
     2101 gaacaaaaaa cggcaaacgg tgcatccgac gctgtccttt gttcacgagc atcgatcctt
     2161 tttttctgtg atgatgaaca gagggcattt ccatcgtttt tttaaggatg tgtttcagca
     2221 ggatgttctc ctgactccgg tccatgtgaa tttgacgccg atcgaacggg aaatttacgg
     2281 acattaccgg gccttgtaca cgtacgcgat tatcctgtat tggctgaatg aggatgcggc
     2341 cgcgactccg gaagctatca gccaaaaggt atgggagctt gtttctcaaa agagatttta
     2401 ttggctgttt ggacaagctg tgccaggaga gcgagagaag ggcaagccaa tcgacaggcg
     2461 ggtggttcga acgagagagg cgctccagca ggcatttctg gacgtattgg cggagaaaca
     2521 agactacgcg ggcatcacga tttcggatat tacgcgtaaa agcaatatcc gccgcgcaac
     2581 tttttatgat cactatgcca ataaagagga attgctccaa accatgatac agcgatcatg
     2641 tgcggagatc attgatcacc tgacgattgc ctcaagtccg aatgagcttt ccttcgaaga
     2701 agcggtggag gcgctcgccg gcctgctttc tgctttagac cgcatgccta ttgtccattt
     2761 gctcaatcgg gactgggttg ttcctcatgt gatacccgag ttgctcaaag cgttggaatc
     2821 attttatctg catcagcaaa ctaatattcc tgcggagaaa aagctttatg cctattatgt
     2881 atcggcgatg attatcgggc tgatattgta tcgactcgat gaagggaagg cgcatgcgcc
     2941 ggaagtgctg gcgaggaagt ttttgcagtt tttggatgtg aagaagtata aggttgtatt
     3001 gctataaacg agagaaacca gccagtggct gaaatggaag gccggagagt aacttcagta
     3061 tgttatgaaa agaaaaccta agagaggtaa cgtttacagg atataaattt gcccggatag
     3121 tcagtccggg ctttgtgtcg ttatgtcact tggtcttgtg agtttctttc ttttctttca
     3181 aagtgaaatt taaaaataga agggctaaaa gaattagcgc aatgttcacc gaccaagatt
     3241 tccagcttga agtaggatct aaaatcgtat tgaagagcaa gtgaatgata gaagaaaatg
     3301 aaaagagtaa aaataatagt ttgttttgcg acataaattg cttgaccttt ctgttgaaaa
     3361 tttagttgta attatagcat aattacataa aacaagaaat aaatccacaa aaatgaaatt
     3421 gcataatagt ttattttgag tgattcactt attctaagta cattatttca gaccggtgag
     3481 taacccataa acagattgcc tctgttggat ttatatttat tatattattg taaatgtagt
     3541 atttctagta gataatcaat gtacctttta gaatccacta taattgatac atcggtctgc
     3601 attccatttt ttaagtgtaa agttgatccg ttatcgttca taactttatt tttctctatt
     3661 gtgctttcag caatataaaa tttttgtccg ttttgatcac taatactgtc tggacttatt
     3721 tttgtaatga cacctttgat ggtttgattt gtattttcaa tatggaatct tacttcatct
     3781 ttctcttttt cattaatatt tgtgatctca tgactcggaa tataaatatt agctttaagc
     3841 ttctctttat cagggataat agtcaaaata gcagtgcctg cttgtaaatt gtcacctgga
     3901 gatatatttg ttagtacatt aacatagccg tcacttgctg cttttatttt atatttttct
     3961 aattgtaaat ctatcatctt tagatcatcc tcttttgatt taagagtggt ctgaagatct
     4021 gtttgctttt gagatgtctg atttagcaag tttgttttga gctgttcaat agaaagctta
     4081 taatttgttt cctctgagtt atcggaatca ctgtcagaat cgtcactttt aattgaactg
     4141 ttaatctcat caagagattg atttaattcg tctttttctt cacttagttt tactaacata
     4201 tcttgtttta aactttcaag ctgtccgttc aagttctctt tctgctgtga aaaacggttt
     4261 ttatcgagct catctttcat cttccgtaga tcatcaagct gctgctctac attttgtttg
     4321 ttagtttgat aactattata gtaagaactg tacttatcat cctgtttggc aaaggattta
     4381 ttgtttttaa tggagtcttg cagatcagaa attctttgaa gctttagttt gactttgttt
     4441 tttgtcttat ccagactatc ttttatgctt tctttctgct tcttaagttt tttctgctga
     4501 gtttttgcat tttcttttga tgactctaac aaaatacttt gtttttcgta cgagagatat
     4561 tgatcttgat aaccccaatg atcgtcctca ctgaataaat ttttgtcatt ttcaatactt
     4621 ttttttagag ttttgtttaa cgcagcttgt tcttttaaat ctttgatatc tgctttaaca
     4681 gcttttttct gcgcttggat ttccgtattg tctagagtta atagagtatc tccctttttc
     4741 accttatcaa cctgtttaat gtcaactgtt tttactttgc cggctacttc gtttgttacg
     4801 ttgctgttag gctttgtata ttggatgtca gctgtcgttt ttagaatcac ttctttcttt
     4861 ccatagaaac taaaaacaat acatgcaata agtaaagcta tcagtatata tgtaaagaaa
     4921 acaccaattg gtttgggttt tgattcatag aattctctgc tatccttcaa atcatgtaaa
     4981 ttgaaaaagt tacgtttcat ctaaattgtc accatctctc ttgatggcat ttggttctcc
     5041 cacaactcat agtacttgcc tttattcttc aataaatcat tgtggttccc atactctatg
     5101 atttctccat tttccatgac aaatattttg tcacaattca taattgtact caaacgatga
     5161 gcaattataa tcgtagttac atcatcagtc tgatcgtata tcatgtttga tattccctgc
     5221 tcagtagtcg tatcgagatt gcttgttgat tcatccatta tgagaatgtt aggttttctt
     5281 aataatgctc tggcaattgc gagtctttgc ttctggcctc cagataaatt agacccgttt
     5341 tcctctacga gagtatcgta tctcattggt aaatcattga caaaatcgtg tacatttgtt
     5401 tgtttgcata cttctataat ctcttcaaag gtaaaactgc ctgagttacc gagcaaaagg
     5461 ttttcaagaa ttgatccttg tataaaatga gattcttgag ggatataact tatactttcc
     5521 cttaacgcgt tggtgtgaat atcatttata tgataaccat tgattaaaac ctcacctgat
     5581 tcagctgtat aaaatttcat taaaagctta gtcaaagtag attttcctga accgctttct
     5641 ccaacaaagg caactttctc tcctttttga atatgcagtg taatatcttt taagatgagc
     5701 cttcgagttc cgtatcgaaa attgatttta ttaaaagaaa gcggacctgt aattgacgac
     5761 gtcgatgtta tttgtgcctc tttctctttt aattcgggtt ctagctttag aatttctccg
     5821 agccttttgg acgcaacaga agctgattga agcttagatt gtaggccgat gatgttttgt
     5881 aaaggattta agaagtaggt taataaggca ttatatgtaa taagctgacc gatagtaagg
     5941 gtgcctttca tgacctgagt tgatccgatc cacagtatca atgcaccgct tgctaaatcc
     6001 aaaaacattt ttatggaact ctgaagatta tcaataactc cgtgtttaaa agctgatcgt
     6061 aagtatttca caaatctttt ttctgtttca aatgacatca tatattccgc attgtatgct
     6121 ttaacagttt cgatgccgtt aagcgtctca acaatctttg aagtcagctg cgcattgttt
     6181 tccatttctg tgttatttat attttcgtag ggttttataa atatccaaac cgtcaaaata
     6241 taaaaaggta tgaaagccaa tgtgatgaga aataaagtag tattctgcag atataagaaa
     6301 ataccaacca taataagcat aatggtatcg agtatgaccg aaagcgatgc actgacaact
     6361 gcatcgatca ctttattagc atcagtaaat ctggatataa tttctccgac ttttcgatta
     6421 ctgaaaaatt tcattggcaa agtaagcaca tgttgaaagt atccaaacat aatggagata
     6481 cttaattttt gtcctaggag aatcattagg tattgcctaa aacctattaa gaaaacctta
     6541 aataaataca taatcaaaag gccgattgaa agaatatgta atgtgttact taatccatta
     6601 ggcaggattt gatcgatgat cgtctgaaag taaaaagtac cgaggatccc gaagatggta
     6661 ataataaagg atgctaaaaa cgtatgtata atcaacgatt tttgctgaag aatcaacctg
     6721 aaaatatcgg cacttatatt acttgtttcg gtctgttttt tataagtctc agtaggtgct
     6781 aaaagtatta agatgcctgt ccaaatctta aaaaaatcat ctttttgata tgtaacgagc
     6841 ccttttccag gatccgcaat gataatctta tctttactaa ttttatgtat aacaacgtaa
     6901 tgcaataatt gctgatctat aataatatgt gcaattgctg gaagcgtaat ggactgatca
     6961 aaagctgtat gctctgcacg cacggctttt gctgaaaacc ccaattgttc ggcggctttt
     7021 accattccaa gagcactagt accttgtgta tcagttccag caatgtcacg tatataagct
     7081 agggagagct ttgaaccata atgttttgca attgttgata ggcaggctgc tccacaatct
     7141 ttttgatcaa gttgtcgtac acaatgatat ctattaaaaa acatatacta ctctccataa
     7201 tgaaggtcat tttttagaat agacatcatt ttattacatt ttcagggttt gtcaaccttt
     7261 ttcaggtaaa tatttattgc tatttagagc ttttggcacg tttatataat ataaatgcgt
     7321 agttgatata gataagatat aaagcaagat taaatacacc taagtgaaaa aaataagaaa
     7381 gagatataca aaataaaccc cctgcgatta tatagctata gaacaatttc attttaccaa
     7441 ctcctataaa tgttaaattc attgtaagat ataatggaca aaatgtaaaa tatatatgga
     7501 taaatgcaat atatagtttg catggttttt tcatgtatga tatgctacag ataaataaac
     7561 caatggagac ttgccaatga ataataattt gaagttggaa agaacaagag cgaatttaac
     7621 acaggaacaa cttgccgaaa aaattggagt gacaagacag acgattggat taattgaaaa
     7681 agggaagtat aatccttctt tacaattatg tttgaaaatt tgtatagaat tgaaagttac
     7741 tctgaatgat gtattttgga cgtataacag ggaggaagaa tctaatgaag gatgagagaa
     7801 taagtcatat tgaaaataag ataggtcatg aaagctttct tttagtaatt gctttggttt
     7861 ttgtctcttt tatactttcg attatgttta aaataccgag tacgttaatg acaattatca
     7921 tattgtttgt tggaagcgga tattatggat taagagctat gtcaaaaggt attttacgag
     7981 tcaatctgaa aaagaagaag aaaagttcgt actttctttt aattgttttt acttttattc
     8041 tgtatatggc aacgtcgata ttatttaaaa tcattacatt tccttttaca actaaagaat
     8101 ttttattcca aattcttatg tatatcttat ggctaattcc ttttagtctc atcatgtata
     8161 ctacatataa attttcaaac aggcagcaga aaaaagaatt agagaattaa ttaagagagc
     8221 ttaacctaaa taactgaatt aggttaagct ctcttttact atatataaat tgatgatagg
     8281 ttatatatat ttttatggaa aaaactattg atttaggatt tattatgtaa tatcataatc
     8341 cacgtggtaa atttttacta gtaattattt acctgaataa cttcgaggag gaatattgat
     8401 ggacacaaaa agcataaaag acgttgaact tcaggcattg actcttgaag aagctgaaca
     8461 aattgatgga ggcagttatg cgaaatatct tggcacttct gttgttacag gtgccggtgc
     8521 gggtgtagtt ggaggagttc caggtgttat tcttggtgcc catgcaggtg caattgcagg
     8581 atcagttggt tatttaggcg gatcattaat tgcaggaaaa tggctttaag gagggataac
     8641 acatcaatgg aaaataataa tcgtttttct gaattaaacg taaaagaaat ggaacaaatt
     8701 gatggcggag gctggagaag tgctcttggc ggagcttttt ccggagcatt agtcggtgct
     8761 tcaacagtag gcgtcggtgg agcagctgtt ggcggccctg ttggcggtgt cggcggagct
     8821 attactggcg gtatagttgg cggcattgtc ggcggaatca atgaatggtg aaaaatacat
     8881 aaacgactag tttagtacta tggtatacga ccggcaagag tcttctcttc ccggtcgtat
     8941 tatattttat aattgttaat taacgcataa aattgcgcag catgtttatt tcgtctcctc
     9001 cttccatttc tcatctaaca gcatcttccc aggccatgta tacgccatga tgccgccgtc
     9061 tgcggtgatg tcttctcctg tgacgtatga gctgtcgtct gaagcgagga acagcgccac
     9121 cgtcgccatt tctttcggct ggccgaggcg tccgagcggt gtgacccact tgtttgcttc
     9181 gcggaacttt tcgcccattt cctgttcttt ggtgcccgct agtttatcaa tcagcggggt
     9241 ttcgatcgta cccggcgaaa tggaattgac gcggattccg tcccgtgcgt agtcaatcgc
     9301 catcgctttt gttaggtttg tgatgccgcc tttttcgagc atgagcggaa tcagatattt
     9361 gctgcaaagg aatgtgccgc gcaggtcgac ggcgataatg cggtcaaaca ggtcaaccgg
     9421 atattcgtgc acctttccgc cttcctgatc aacgccggcg ttattaaaca aaatatcaat
     9481 cgttccgcac gcctccttga tttgatcagc aaaagctttc acgctgtttt catctgacac
     9541 atcgaggtga aaggcgtccg cctgtcctcc attttgtctg attgcttcaa ctgtttcttt
     9601 catttggtct tcattgatgt ccccgatcat cacacgcgcg ccttcattgg caaaaacctc
     9661 tgccgtcgct tgtccaatgc ctgtcgcggc gcctgtgatc actgcggttt tgttttcaag
     9721 tcttcccatg acacgacctc ctttttctat ttgtcttccc gctctgtgca gtcataaaca
     9781 tgcgagaaag gaaatgcatg tgttaagata ggctggaaat tggttggggg gtgtgtgagt
     9841 tgaaaatcca gcataagaag gagctcaagt tttattgctt cgttacaatt ccatctgcat
     9901 ttattctgct gactctcatc tcgtttctat tcaaagagat tacatttcca gttacagcaa
     9961 gcgcgtttct aaatgcttca tggcataatc tattattttt gataccgttc ggtttgtttt
    10021 tctatccggt gcatatttgg atgaagcggg agtttggccg ctggaatgac acagaaaaaa
    10081 agagaggatg atgaagcctc tcttttttat gagaatgagt gagaaaaaga gtgaaaacaa
    10141 atccaactaa tgttaaattt acatatatat gcatctatca atctaattga caattgtcat
    10201 cttatgtgat aaatagatgc tgaaaagggt ttacataatg gtaaaggagc gatcaagagt
    10261 ggcaaaaaaa gagtttaaag cagagtctaa acgcttgctg gatatgatga ttaactccat
    10321 ttatacccaa aaagaaattt tcctgcgcga gttaatctcc aattcgagtg atgcgattga
    10381 caaaatctat tacaaagcgc ttacggacga tgcgcttacg tttgataaag acagttacta
    10441 cataaaggtc gcagctgaca aagatgcgag aacattaacc atctctgata cggggatcgg
    10501 aatgacaaag gatgagcttg aacagcatct tggaacaatt gcaaaaagcg gttccctcgc
    10561 gtttaaaaag gaaaacgagc tgaaagacgg acacgacatc atcggccaat tcggtgtcgg
    10621 tttttacgcg gcatttatgg ttgccgatgt cgtgacagtc atcagtaaag cgctgggcag
    10681 cgaagaggct tataaatggg agtctgcggg tgcagacggc tatacgattg aaccgtgtga
    10741 aaaggattct gtcggtacag acattatcct gaaaatcaaa gagaacacag aagatgacag
    10801 ctatgacgag tttttagagg aatatcgttt aaaagcgatc atcaagaagt actccgactt
    10861 cattcgctac ccgatcaaaa tggatacaac cattaataag ccgaaggaag gcagcgaaaa
    10921 tgaatttgaa gaggtgcagg aagagcagac ggtcaacagc atggtgccga tctggagaaa
    10981 aaacaaaagc gagctgacag atgaggatta tgaaaaattc tatgctgaaa agcattacgg
    11041 gtttgataaa ccgctcacac acgttcatat cagtgtagat ggagccgttc gctacaacgc
    11101 gattctattc gtccctgaaa acatgccgtt tgactactat tccaaggaat atgagaaagg
    11161 cttggagctg tattccaatg gcgtgctgat catgaataag tgcgcagacc tgctaccgga
    11221 ccacttcagc tttgtgaagg gcatggtcga ttctgaggat ctatcgctga acatttccag
    11281 agaaatgctg cagcatgacc gccagctgaa gctgatcgcg aaaaacatca gcaagaaaat
    11341 caaaagcgag ctgcaaagcc tgttgaaaaa agaccgcgag aaatacgaga cgttctacaa
    11401 gtcgttcggc agacagctga aattcggcgt gtacaatgat tttggcgcga ataaggatca
    11461 attgaaggat ctcctcttat tctactcttc aaaagagaaa aaactggtca gcttagacga
    11521 gtatgtttcc agaatgccag aggagcagaa attcatttat tacgcgaccg gtgattctta
    11581 cgaccgcatt gagaaactgc cgcaaacgga aatggtggcg gacaaaggct atgaaatcct
    11641 ctactttact gaggacatcg atgagtttgc aattaaaatg ctggcttctt atcaggaaaa
    11701 agaattcaag tccgtatcaa gcggagacct tggcatagac acggatgagg atcaaaagca
    11761 gtccgaggaa gaggaaagca agtataagga tctgtttgag gaaatgaaaa acattctgtc
    11821 agacaaagtg aaaaacgtca gaatctcaaa acggcttaaa tcacatccag tctgccttgc
    11881 tgctgacggc gaagtgacaa ttgagatgga aaaaatctta aatgcgatgc ctgacagcca
    11941 aaatgtgaag gcggaaaaag tgctggaaat caacccaaat cacgaggtat tccaaacact
    12001 gcaggacgcg tttgaacaag ataaagagaa gctgagcctg tacacaaacc ttctgtacaa
    12061 tcaggcgctc ctcatcgaag gcctgccgat tcaggaccct gtggaattta cgaacaatat
    12121 ttgcaaggtc atggtgtaaa cagaaaaagg aatcgtccca taaggagacg attccttttt
    12181 ttataatgta cgctcattca gcacttggtt ttgggtgctt ttcttctttt taaaccgttt
    12241 tttcaggctt gcttcaattt cctccaagct tttccctttg gtttccggca ccatgtagaa
    12301 cgcgaagaaa aatgagagaa gacaaatgac tgagaaaacc ataaagaccc atgcgatgcc
    12361 catcgcgctt agcatcagcg gaaagacaag cgacacgatc aggttagccg ccgataacac
    12421 caaagtcgtg aaccctgtcg cggctccgcg tgctttggac gggaagagct caggcatgag
    12481 cacccacact accggacccc atgtcgcctg gtaaaagacg atatagacac ctagaaagac
    12541 tactgtcatc cacgctgttg atgcggaaag tccgagcgtt aggagcacgc ctgataaagc
    12601 agcaaggctc agtgtgatgc cgacacttcc ccagatcaga agttttttgc ggccgacacg
    12661 gtcaattaag atcatggcag tgatacacat gatgacgttg aggatgccga tccccattgt
    12721 gccgagcgcc gaagctgatg tgccaagacc ggccttcgta aaaatggttg gcgcgtagta
    12781 gatgaccgtg ttaatgccga ccgcctgctg gaaaatggca aggccgacgc caatcagaag
    12841 catggggcga atccatttgg cttttaggac gctgagtgtc gtttcttttt tctctgcttc
    12901 tccttgcttc atctctgcca attccatttc gatgtctttt ggatcatgag tgatgttcat
    12961 gattcgtctc gcttcttctt cacggccgcg cttcacgagc catcttggcg attccggcat
    13021 gaacgcgatg ccgattaata aaagcacggc aggcactgcg gccagaccga ccatccagcg
    13081 ccacgcttca aacggtgtga acagataggt aacgatatag gcgagcaaaa tcccggtgac
    13141 aatcattaag ttgttcattg tgccgagtgt cccgcgaatt ttcgtcggtg ccatttcgga
    13201 aagatacacg ggcacaagcg ccgttgaacc gccgacggcc aacccgagca tcaccctaga
    13261 tgcaatcagc atgccgattg tttgagaaaa cgcgcaagcg agcgctccga taatgaaaat
    13321 gatggaaagg acaaatacaa cctttctcct gccccagcgg tcggagcatg tgccgctcaa
    13381 ggcagaaccg aaaatcgcgc caaggagcag catgctgaca accaatcctt ctgtcaatgt
    13441 cgttaaagga atatcgttat tgataaacag gagtgctccg gagataacac ctgtatcgta
    13501 accatatagc agtcccccta aagcgccgaa aaagtagatc atatatttcc ttgtgtcttt
    13561 cttcacaaat gtctcctcct cagttgttga gccaatgagt atctaaaatg tgtaacaaag
    13621 ttaatagatt agtacccatt tcctatctca tttgaaacat ttgttttgaa aaaacggaaa
    13681 cgttaaagct aaaagagatg atcacagatc cgctgagttt aggaaaaacg aaataacttt
    13741 atgctcagag aaaccattaa aaaaacctta cccgcgcgga gtaaggtttg attaagacat
    13801 ttttattctt ctgcttcgtt gacgaaaacc aaggcggaga agcctttttt cttatcaaat
    13861 tgcaattcaa c
//
