LOCUS       c00010_JAGHHY0..       16159 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAGHHY010000031.1 Ligilactobacillus salivarius isolate MAG.343
            k127_1329546, whole genome shotgun sequence.
ACCESSION   JAGHHY010000031
VERSION     JAGHHY010000031
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 12:11:27
            Original ID  :: JAGHHY010000031.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 105212
            Orig. end    :: 121371
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16159
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[110212:116371]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..11159
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..16159
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16159
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(714..1790)
                     /locus_tag="ctg10_96"
                     /transl_table=11
                     /translation="MNINKIFLLNFNDTNDFNIKQVAIENDKVVSFSKSIKNISEYGMK
                     NYFDLAESLENPKKYSISLGENDEKTYHIDLLEKIRSSLDEADFLENIELAVDNGKLLY
                     NIAIYVEDDEKYTGIYIYEIKESHLLRDDFYVMKIPFTKQKINLKKKGAGTTNEKLAVV
                     ENVAGSVGLPTEGCIVSFFKRKKDDEQYKIYKVKVYDAWKFDDVFGKVETRKKYVRFTL
                     EKFANEENPIKIANDAVQVVFKNEDEETSNVVDTVEAVIMSDMKLVKTFSNFHNNSRRK
                     IKNIEVSRLREVLNLLKDYVLNNAEANFELKNIPTLDEKGNLIVNADSTPIFAALLENK
                     IIQRLLNNDIEIPYYKKD"
     CDS             complement(1795..2256)
                     /locus_tag="ctg10_97"
                     /transl_table=11
                     /translation="MLLSILVDLYSLVRVIQLLNNQKKLTKALGTNSVRISNEYNGGLR
                     DFLLSFIVPAITTFSADENPLTMIIFILLFQFIVYVFYKNSSDFFPNISLMFMGYSVFK
                     VDTYDLGGIEYVFGKTKNIDDIILKKVDVIMIGDKNYPNNVAIILEKKV"
     CDS             complement(2769..3173)
                     /locus_tag="ctg10_98"
                     /transl_table=11
                     /translation="MKKVLVDTCVIIDILLDREKFVDDSYSAVSKLIRKGDTICTTAKA
                     MTDIFYIVHHSLHDNDKTKEVLLKLSRVYQILDTKEKDTIMAITSDVADYEDAVMVETA
                     IANKVDFILTRNIKDYKKAKIKVISPTELN"
     CDS             complement(3173..3394)
                     /locus_tag="ctg10_99"
                     /transl_table=11
                     /translation="MTQVTATELKNNLGKYLKKSEFEDIYITKNGVIVSVLSNPNQSKL
                     QMLDDLKGIAPDMNMTDEELRSERISNI"
     CDS             complement(3837..4985)
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 56.4; E-value:
                     3.8e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg10_100"
                     /transl_table=11
                     /translation="MEDKFLESSEFYSARFRNFSTMIIIPFTILLLAVVIFSFFGKKEI
                     TIQGAGTLEALGNNPVIQSTVNSPIEKNYLKEGKYVKKGDTLLVYNNVNIQDKGKLYNS
                     QKEILDRQLAALNLLKQGVQDNHDSFGEDDEFGYRNDLKSYLQQRNTYLTENTMIQDKS
                     KNDKAKQSSINNELKKQGGSATSIADFDSSKYDIDINNQKMSDLQSSKLSSIDQEIIKI
                     KQNISELNANIDENNNTNREYKVKAVRDGILHINDEYSESHYISAGANLAQILPILKNQ
                     KTLKIKAYISTADISSIKVGQKVRFKVTRNVPKPIILTGKIHKISISPVEIGKENYYQI
                     EAKTDIQNTNRDLLKYGMQGQMVVITGKTTFFEYYKDKLFNR"
     CDS             complement(5001..7160)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 313.3; E-value:
                     5.6e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_101"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1080.3,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 3e-44, bitscore:
                     143.6, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHKYKKYYIPQVDESDCGVASLAMILKHYGSSLSLAYLRNIAKT
                     TMEGTTALGLVKTAQTLGMETQAVKADMSLFGMKDITYPFIVHVVKEETLLHYYVVLKA
                     TPNYILIADPAPDVGITKMSYERFEKEWTGITLFIVPGIEYKPTKETRQSLISLFSKLF
                     KQKQLIVNIVLAALLITIISILGSYFLQGIIDTYIPNGMHSTLAIIAFGLLVIYVFNSI
                     FTYARDFLLAILGQRLSIEIILSYIRHIFELPMEFFATRKTGEIVSRFNDASKIIDALA
                     STVVSIFLDVSIVVIMGIILAIQNLKLLGITLISLPIYTIIILTFTKAFERLNNKQMES
                     NAILSSSIIEDIQGIETIKALNSEQMRYRKIDSQFVDYLRKSLAYIKTDSLQQALKLFI
                     QQTLNVIVLWLGANLVISNQLSIGQLMTFNALLSYFVNPLQNIINLQPKLQSARVAHNR
                     LNEVYLVESEFKDRKAVHDVTQLQGNIIFQDVDYRYGYGENILDKVNLTLKQGEKLTIV
                     GMSGSGKSTLVKLLVNFFAPVSGSIKLNNHDINNIDKHTLRSYINYIPQNPYIFAGTIE
                     DNLRLGNRSNVTDEDILMACKIAMIDTDIAKMPLQLKTKLDENANILSGGQKQRITIAR
                     ALLSPAQVLIFDESTSGLDAITEKKLIDNLMKLKSKTIIFIAHRLSIAKRTNNILVLDG
                     GKIVEKGRHDELLAKKGYYYNLINS"
     CDS             complement(7371..7568)
                     /locus_tag="ctg10_102"
                     /transl_table=11
                     /translation="MKINKKFYKNYTFYIGLVMLSIAVGSIFLDKGYFLFTIIDILFTC
                     LGIKYVYQSLVLTKRYERNR"
     CDS             complement(7813..8052)
                     /locus_tag="ctg10_103"
                     /transl_table=11
                     /translation="MVEIGIIILLVVGFMVISRLKVNFTKNSRYAGFLLLILLDLNGLM
                     RTPMLTVRGLILLGTLMIFVIMLIKEIRQNRKYS"
     CDS             complement(8089..8883)
                     /locus_tag="ctg10_104"
                     /transl_table=11
                     /translation="LEEYGIIICDDEKDQVRRIHDLVKYAIWSLEDSADSKDKEFKITL
                     EANSYIEVADYLEDNKVDSGVYFLDIELSRDKADRDGIDLAEFIRQRDPNAQIIFITAY
                     ENLAAMTYRRRTGALDFITKNDSDEVIQKRLNETLSLAARRIRESHAIKKMTFSYKMGR
                     RIINENINDILYIITTPKSHRLEIVTVNGMGEFTGDIKKLEAENDFLEKISQSCLANPS
                     NIVEINLSTRVISFKDGYKETFPRRSKAKMKSLIERYNLKTV"
     CDS             complement(8897..10189)
                     /locus_tag="ctg10_105"
                     /transl_table=11
                     /translation="MTDIVDIYNRYNIILYAVGLFISVACDYLFFYLITPINRSKKQNI
                     LFTIITFPIVFLYHGGGDLGAFCAELFEVSAFYIVYKRRKRDYQVLGRILILLLYSYLS
                     FEIEFLLSQIISQYISALPIDTIVINILEYYILMKTDIIKNLDDEYGKTFFYLIIYLLV
                     SFAGIYYLTGYLFKVDKVLYLILLVVIIVQLIFSLYIYNNSKKIRQDKLSLQQIKDLKI
                     YTQQLESSQRSLRKFKHDYQNMLVSLKLSAKKNHDKELIDKLAEYSSKILEDKVLWQFN
                     DVDNIKDELLKSLFISKLNRIFQDNIQYSFECRDVIDSLSNEYNAFDIIRILGITYDNA
                     IEESLELGDEARIDTMVYRENGELEIEIKNRCRNTDLTIQDMKKSGFTTKKNHDGLGLA
                     NIEELSQPYNDIFINYQIKDGWFTFLMVMSI"
     CDS             complement(10191..10310)
                     /locus_tag="ctg10_106"
                     /transl_table=11
                     /translation="MKFEVLTEKKLQVIVGGKQEGGTKTYDKVCRFKFLGICK"
     CDS             complement(10741..10947)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_107"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 3.6e-11,
                     bitscore: 36.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLDKRFTIMTEDNLASVNGGKNGYGGSGNRWVHCGAGIVGGAL
                     IGAIGGPWSAVAGGISGGFASCH"
     CDS             complement(10965..11159)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_108"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.8e-16,
                     bitscore: 53.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKEFTVLTECELAKVDGGKRGPNCVGNFLGGLFAGAAAGVPLGP
                     AGIVGGANLGMVGGALTCL"
     CDS             complement(11165..11422)
                     /locus_tag="ctg10_109"
                     /transl_table=11
                     /translation="MLKKLWETWLDGGFIRGKKRYVIAPVIWALLIPLGIWLFGNEDMS
                     YLDYIQTPKMIIVAIFCLIGGSTLLYLLDTTMKVNKHMKG"
     CDS             complement(11552..11725)
                     /locus_tag="ctg10_110"
                     /transl_table=11
                     /translation="MNNNFVQIDKKELAHIIGGRNSYDYIDSGKFGYDIGCTIANTKFF
                     KRLRHSNQNICS"
     CDS             11958..12221
                     /locus_tag="ctg10_111"
                     /transl_table=11
                     /translation="MNSFSNNINFSKISVSLITLFLLIWTLVDGNLIHLGILAFSSLVT
                     TMLHFHYFEATDDKHPLNRIDFGLQLLFIFISIIKFFLISGR"
     CDS             complement(12260..12589)
                     /locus_tag="ctg10_112"
                     /transl_table=11
                     /translation="MKAIYKGKEVQIWQISKTAEQPEWIKAAFKANYLKWSGDKLLFIM
                     NGVKAPVKISAWTNFKTLFNGASGWWATYASGYIGDYLDFTNRKIISERKFKKKYKIVD
                     TYVNK"
     CDS             12811..13779
                     /locus_tag="ctg10_113"
                     /transl_table=11
                     /translation="MRYIKFTLLIYSFLLTWGITTNSISADEVTPTTTSETTVTPQSQS
                     TSVDSNDEDAAIEEKFYSHDVTIDEYNQNVANFNKVNTDTVKTMVTENSNNLDQVLYIG
                     RPTCYFCRQASPHLRDFNQLINNQLYYYDIDAEPSAHDFAFKEIGIPGTPTTMRLKNGK
                     VVSAWIGGEKTGQEFYDFLFSADANKLADSYTIKKTVSANTSNTVITNNQNIKPTIKPI
                     PTNINQLKEEKTTPELVNTTSQSSKPVKKVQKQTTNKENKNSVLPQLGAVPLYHQPLFK
                     LPIPRLIPKRLERIIALVSFLVLYIGITIWTGLSLKNWDKK"
     CDS             complement(13962..14303)
                     /locus_tag="ctg10_114"
                     /transl_table=11
                     /translation="MKAIYRGRKVDVWQVSRDNVQPDWVKDAFEHNGLRWLHGSGNKVR
                     IYWPAVTRAKKGIIRTILNGISASLVSINGGSTAMYDIGFEGDVIDFTNSKVVTAEKFA
                     KKYRVVSEE"
     CDS             complement(14324..14590)
                     /locus_tag="ctg10_115"
                     /transl_table=11
                     /translation="MDYLVIKAIIWIFFIISAILKVNYKKKHGELDKRARKQATLGTFL
                     IVTTIFDEGYENKILYIIVLIALLVYIVLVIYRLVMAIKDRKK"
     CDS             complement(14757..15935)
                     /NRPS_PKS="Domain: Aminotran_1_2 (32-385). E-value:
                     1.3e-71. Score: 233.3. Matches aSDomain:
                     nrpspksdomains_ctg10_116_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 278; E-value: 2e-84)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_116"
                     /transl_table=11
                     /translation="MKFEKSEILKNLPKQFFANLVIKVNKKIAEGVDVINLGQGNPDKQ
                     TPEYIVKSTQRWVASPQSHKYSLFRGQPDFKQAVADFYQEKYQTTFDPEKEVAVLGGSK
                     TGLVELPLALMNPGDVFLLPDPGYPDYWSGATLGQVTFEKVPLLKENNFLPDLKSIPEE
                     LARKAKFFYINYPNNPTGATATREFYEELVAWAKKYEVGIISDFAYGAIGFDGERPLSF
                     MEIPGAKDVGIEFYTFSKTFNMAGWRVAFAVGNADIIDALNLIQDHLFVSIFPALQYAG
                     IDALKAPERDAEINKIVDRYETRRNAFIQAAEKIGWKAFVPKGTFYAWMEVPKGYSSEE
                     FADLLLNEAGVAVAPGNGFGEYGEGYVRIGLLIEPERLEEAVDRIAKLNLFK"
     aSDomain        complement(14781..15839)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg10_116_Aminotran_1_2.1"
                     /evalue="1.30E-71"
                     /label="ctg10_116_Aminotran_1_2.1"
                     /locus_tag="ctg10_116"
                     /protein_end="385"
                     /protein_start="32"
                     /score="233.3"
                     /tool="antismash"
                     /translation="DVINLGQGNPDKQTPEYIVKSTQRWVASPQSHKYSLFRGQPDFKQ
                     AVADFYQEKYQTTFDPEKEVAVLGGSKTGLVELPLALMNPGDVFLLPDPGYPDYWSGAT
                     LGQVTFEKVPLLKENNFLPDLKSIPEELARKAKFFYINYPNNPTGATATREFYEELVAW
                     AKKYEVGIISDFAYGAIGFDGERPLSFMEIPGAKDVGIEFYTFSKTFNMAGWRVAFAVG
                     NADIIDALNLIQDHLFVSIFPALQYAGIDALKAPERDAEINKIVDRYETRRNAFIQAAE
                     KIGWKAFVPKGTFYAWMEVPKGYSSEEFADLLLNEAGVAVAPGNGFGEYGEGYVRIGLL
                     IEPERLEEAVDRI"
ORIGIN
        1 ccgaatactc gtctattttt aacggattcc aatataggaa ctatttttat attagttttg
       61 gctatttttg tatgtgtttt ttctgtaatt tataataaac actctcgttc tctttggtat
      121 atattttctt ttatattagg attaagtcct atactatttt taattttcgt tggtattttt
      181 ttagcattag gaatgccttt tgcaccatga ttaactttca agtagaaacc ggaaaaattt
      241 aaaaaatcgg ttctattcta tagcttgata aatagtaata agtctgctgc atattaagta
      301 agttaacaag ccatagatag ttattagaga gtaagagaat aataatagta atttaacagc
      361 taatagagaa taaattgata atgatgagtt agatagctgt cagatagtaa agcggttact
      421 tatagaattg agtaggagat aattgattaa ttcaattatc gacctctcac accaccgtac
      481 gtacggatcc gtatacggtg gttcgacaat ttaatcactt tgtattgact ggagtatctt
      541 gaacatgttt attagtccta gttgctccag tcttctatta gttagggtat acgcccacag
      601 cggactctca ccgcctagct atcgcccatg ccgggcgcac cacaaaagta gctggaatca
      661 tctgattctg gctacttttg ttttatatca ggtatcaaag gccaaacata cattcaatct
      721 tttttataat acggtatttc aatgtcgtta tttaataatc tttgaattat tttattttct
      781 aataaagctg caaatattgg tgtagagtct gcatttacta ttaaatttcc tttttcatct
      841 aaagtaggaa tattttttaa ttcaaaattt gcttcagcat tattcagtac ataatctttt
      901 agtaaattta atacttctct taatctagaa acttctatat ttttaatctt acgtctagaa
      961 ttattatgga aattcgaaaa agtttttact aatttcatat ctgacataat tactgcttct
     1021 accgtatcta ctacattaga ggtttcttca tcttcattct taaatactac ttgaacagca
     1081 tcattcgcta tttttatagg attttcctca ttcgcaaatt tttccagtgt gaatcttaca
     1141 tacttctttc gagtttctac ttttccgaaa acatcgtcaa atttccatgc atcataaact
     1201 ttaaccttat atattttgta ttgttcatca tcttttttgc gtttaaaaaa gctaactata
     1261 catccctctg tgggcaaccc tacagagcct gccacatttt ctactaccgc taatttttca
     1321 tttgtagttc ctgctccctt cttttttaag ttaatttttt gtttagtaaa tggtattttc
     1381 atcacataaa aatcatctct taataaatga ctttctttta tttcgtaaat ataaattcca
     1441 gtatattttt catcatcttc aacatatatt gcaatattgt acaataattt tccgttatca
     1501 accgctaatt caatattttc tagaaaatcc gcctcatcta aagaagacct tattttttct
     1561 aataagtcaa tatgatatgt tttttcatca ttttcgccta aacttataga atatttttta
     1621 ggattctcta aagattcagc taaatcaaaa tagttcttca ttccatattc tgaaatattc
     1681 ttaattgatt tagaaaaaga aactactttg tcattttcta tcgcaacttg ctttatatta
     1741 aagtcatttg tatcgttgaa atttagcaaa aatattttat ttatgttcat gtaatcacac
     1801 ctttttttca agaataattg ctacattatt agggtagttt ttatcaccta tcataatcac
     1861 atctactttt tttaaaataa tatcatcaat attttttgtc tttccaaaaa catactctat
     1921 acctcccaaa tcatatgtat caactttaaa aacagaatat cccataaaca ttaatgaaat
     1981 atttggaaaa aagtcggaag aatttttgta aaatacatat acgataaatt gaaaaagtaa
     2041 aataaatata atcatagtta atggattctc atcagctgaa aatgttgtta ttgcaggtac
     2101 aataaaacta agcagaaaat cccttaatcc accattatat tcattagaaa ttctaacact
     2161 attagtacct aatgctttag ttaatttctt ttggttattc aataactgaa taacacgaac
     2221 taacgaatat aaatctacta atattgacaa caacattatt aatattgtaa tttttgacga
     2281 ggtagatgac actttaaaca aattctcaca attgttattt tctagtttag aagaaaatat
     2341 aaatactaat actgagatat gtatcggaaa caacgaggac acataataat agagcttaaa
     2401 tttctcacta gaggatctaa acatagtttt ttaattgccc tcctttcttc aaaacattaa
     2461 acagtactaa atatacaata agtataacaa aatagtatta ctttttgtaa cacaaattta
     2521 atcaattaaa atctaaaaaa tgccactcct acaaagaagt gacaaagaca actatatacc
     2581 cgatatgcta tactagatag cgaaaaatta aaaagtaact tgcagaaaac gtttctttag
     2641 agagaaactc tggaagttat ctttataatg ataagttaga taactgttag atagtaaaac
     2701 ggttacttat agacaataaa aaatctcttc atttaaaagg agattctgca tttcttttta
     2761 ggataaattt aattaagctc tgttggacta atcactttta ttttagcttt cttataatct
     2821 ttaatatttc tcgttaaaat aaaatccacc ttgttagcga tggccgtttc aaccataaca
     2881 gcgtcctcat aatcagctac gtcagaagtg attgccatta tggtatcttt ttctttggta
     2941 tcaaggatct gatagactct acttaacttt aacaagactt ctttagtttt atcattatcg
     3001 tgtaatgaat gatgtacaat ataaaaaata tctgtcattg ccttagctgt cgtacaaata
     3061 gtatcgccct tccttattaa cttagaaaca gcgctataac tatcatcaac aaatttttct
     3121 ctatccaaaa gaatatcaat aataacacac gtatcaacta aaactttttt catcagatat
     3181 tactaatcct ttcacttctt agttcctcat ctgtcatatt catatctggt gcaattcctt
     3241 ttaagtcatc taacatttgc agtttacttt gatttggatt agataaaact gatacaatta
     3301 ctccattttt agtaatgtat atatcttcaa attctgactt ttttaaatac ttaccgagat
     3361 tattctttaa ttcagttgct gtaacttgtg tcatttaaac cacctccaca aattaattat
     3421 accacaaatt agctaatcat atagtaaaaa cagctaatac taaatataaa attagctaaa
     3481 tacgaattat attaactatt gcttaaaaac aacacccatc aaaaaaatcc catcagtatc
     3541 tactaccatg aactttttat ttatcaacat tacctctacc aataatatta agaataaaac
     3601 caaatacttt ccatgataat aacttccttt gtataatgtg atgttgctat attcattaat
     3661 gcaactacat taattttttt gaattgatat atactaaaaa atattataat tcctattgat
     3721 aaaaagaaaa aatctaatat ttcaaaattt aaattatctc caccctcatc ttaaaaagag
     3781 ctgaagatat tccagctctc acaaatattt tatccagtaa aggcgtacaa attaatctat
     3841 ctattaaaca acttatcctt ataatattca aaaaatgttg tcttacctgt aattacaacc
     3901 atttgccctt gcataccata cttcaataaa tccctattgg tattttgaat atctgtttta
     3961 gcttcaattt gataataatt ttctttccct atctctactg gagaaatcga tatcttatgt
     4021 atttttccag tcaaaataat aggtttaggt acatttctag ttactttgaa tcttactttt
     4081 tgccctactt ttatggaaga aatatctgct gtacttatat atgcctttat ctttaaagtt
     4141 ttttgattct tcaaaatcgg cagtatctga gctaaattag cccctgcact tatataatga
     4201 ctttcactat actcatcgtt aatatgtaaa attccgtctc taacagcctt taccttatac
     4261 tctctattag tattattatt ttcatcaata ttagcgttca attctgatat attttgcttg
     4321 atttttataa tttcttgatc aatagaactt aacttacttg actgtaaatc actcattttt
     4381 tgattgttta tatcaatatc gtatttagac gaatcaaaat cagctatact tgtagcagac
     4441 ccaccttgtt tcttcaactc gttattaatc gaactttgtt tggctttatc gtttttagat
     4501 ttatcctgga tcattgtatt ttctgttaaa tacgtattcc tttgttgtag gtaactcttt
     4561 aaatcattac ggtaaccaaa ttcatcatct tccccaaaag aatcatgatt gtcttgaaca
     4621 ccttgtttaa gtaagttcaa agctgccaac tgtctatcta agatttcttt ttgtgaatta
     4681 tacagtttcc ccttatcttg tatattcaca ttattataaa caagtaatgt atctcctttt
     4741 tttacatact ttccttcttt taaataattt ttttcaatag gactatttac agttgattga
     4801 ataacaggat tatttcccaa tgcctcaagc gttcctgcac cttggatagt tatctccttt
     4861 tttccaaaaa agctaaaaat tactaccgcc aacaataaaa ttgtaaaagg aataataatc
     4921 atagttgaaa agtttctaaa tctagctgaa taaaattcgc tactttctaa aaatttatct
     4981 tccataatac aatactcccc ctaactatta attaaattgt agtaatatcc ttttttagct
     5041 aataattcat catgtctacc cttttctaca atttttccgc catctaatac tagaatatta
     5101 tttgttcgct tagctataga taatctatgt gcgataaaaa ttatagtttt tgactttaat
     5161 ttcattaaat tatcaattag ttttttctcc gtaatggcat ctaatccact tgtagattca
     5221 tcaaaaatta atacttgtgc tggagataat aaggctctag caattgtaat tctttgtttt
     5281 tgtccacctg ataagatatt agcattttca tctagtttag ttttcaattg tagtggcatc
     5341 ttcgctatat ctgtatcaat cattgctatt ttacaagcca tgagaatatc ctcatcagtt
     5401 acattagatc gattacctag tctaagatta tcttctattg tcccagcaaa aatatatgga
     5461 ttctgtggta tgtaattaat ataagaacgc agagtatgct tatcaatgtt atttatatca
     5521 tgattattta gttttatact acctgaaact ggggcaaaaa aattcaccaa tagtttaact
     5581 aacgttgatt tgccagagcc actcatacct actatagtta gtttttctcc ctgttttaaa
     5641 gtcaaattaa ccttatccaa aatattttca ccatatccat agcgatagtc aacatcttga
     5701 aatataatat ttccttgaag ttgagtgaca tcatgaacag cttttctatc tttaaattca
     5761 ctttcaacta agtaaacctc attcaaacga ttgtgagcta cccttgcact ctgcaatttt
     5821 ggctgtaaat ttatgatatt ttgtaacgga ttcacaaaat aacttaatag tgcgttaaaa
     5881 gtcattaatt gtcctataga gagttgatta ctaattacca gatttgcccc taaccatagg
     5941 actataacat ttaatgtttg ttgaataaat aactttagtg cttgttgcaa cgagtctgtt
     6001 tttatatatg ctaacgattt acgcaaataa tccacaaatt gactatcaat tttgcgataa
     6061 cgcatttgtt cgctgtttaa ggcttttatt gtttctattc cttgaatatc ttcaataata
     6121 gatgaactaa gtatcgcatt actttccatt tgtttattat tcaatctttc aaatgctttt
     6181 gtaaatgtaa gaataataat cgtgtaaatt ggaagtgaga taagagttat ccctaataat
     6241 ttaagatttt gaatagccaa gattattccc ataataacca caatgcttac atctaaaaaa
     6301 atagatacta cagtgcttgc taaagcatct ataattttac tagcatcatt aaaacgagag
     6361 actatttccc cagtttttct ggtcgcaaaa aattccatag gcaactcaaa aatatgtcta
     6421 atataactta aaataatttc aatcgaaagt cgttgtccta aaattgctaa taaaaaatcc
     6481 cttgcatatg taaaaattga attgaacaca tatattacta gtaatccaaa agcaataatt
     6541 gccagtgtac tatgcatacc attaggaata tatgtatcaa ttattccctg taaaaaatat
     6601 gatcccaata tactaataat tgtaattaac aaagctgcca atacaatatt aactattagt
     6661 tgcttttgct taaataattt actaaatagt gatattaatg attgtctagt ctcttttgtc
     6721 ggcttatatt caattcctgg aacgatgaat aaagtaattc ctgtccattc tttttcaaaa
     6781 cgttcatacg acattttagt tatccctaca tctggagctg gatcagcaat taaaatataa
     6841 ttaggtgttg ctttcaatac tacataataa tgtaataacg tctcttcttt aaccacatgt
     6901 acaataaatg gatatgtaat gtctttcatt ccaaaaagag acatatcagc ttttacggct
     6961 tgtgtttcca ttcctaaagt ctgtgctgtc ttaacaagac ctaaagctgt agtcccctcc
     7021 attgttgtct tagcaatgtt tcttaaatac gctaatgata gcgatgatcc atagtgtttc
     7081 aaaatcatag ccaacgaagc tacgccacaa tcagactcgt ctacttgtgg gatataatat
     7141 tttttgtatt tatgtatcat aagttaatat ccccctatta aacttattat ctttcatctc
     7201 ttttattaag catatcatgt tcttaaatta tcttgcctaa atcatcaaat ctggtccttt
     7261 ttatacttat ttggtattag tattttcttt aacttgttaa aataaaaagc taaaaaaatc
     7321 attgagtaaa ttttaatttg atttttccta gctttcttaa tttattaatt ttaacgattt
     7381 ctttcataac gctttgttag caccaatgat tgatagacat attttatacc taggcaagta
     7441 aataatatgt caataattgt aaataaaaaa tatcctttat caagaaaaat acttcctacc
     7501 gctattgata acattactaa accgatataa aaagtataat ttttataaaa ctttttattt
     7561 attttcatat actactcccc atttccacta ataatttcag ctagattttt ccattataca
     7621 atttcatttc ctagccttaa tttatcatat tcttaaatca ttgtgtctaa attatcaaat
     7681 ttggtctttt tttagattta tttggatact aaaagtgttg ttaaaatgta gattagtcaa
     7741 taatcatttg caaagataat catgaatgtc atataaagag gattggaata ccctaagttc
     7801 caaccctctt tattaactat attttctatt ttgtctaatt tctttaatca acataatcac
     7861 aaaaatcatc aatgttccca ataagattaa acctcttact gttaacatag gagttcgcat
     7921 aagtccattt agatccagta atattaacaa taaaaagcct gcatatctac tattttttgt
     7981 aaaatttact ttcaaccttg aaattaccat aaaccctaca actagtaata tgataatacc
     8041 tatttctacc atgtcatttt caccacctat atcaataaaa acaaaagatt aaactgtttt
     8101 caaattatac ctttcaatca aacttttcat tttagcctta cttcttctag gaaaagtctc
     8161 tttatatcca tctttaaaag aaataaccct tgttgacagg ttaatttcaa caatattact
     8221 tggattagct aaacaagatt gtgatatttt ttctagaaaa tcattttctg cctctaactt
     8281 cttaatatcg cctgtaaact cacccatacc attaactgta actatttcta atctatgtga
     8341 cttaggagtg gtaataatat atagaatatc attaatattt tcgttaataa ttcttctgcc
     8401 cattttatag ctaaatgtca ttttctttat ggcatgagat tccctaattc tccttgcagc
     8461 taatgataaa gtctcattta gtcgcttttg aatcacttca tcactatcat ttttagtaat
     8521 aaaatctaac gctcctgtgc gacgtcgata ggtcattgct gctagatttt cataagctgt
     8581 aataaaaatt atctgtgcat ttggatctct ttgtctaata aattcagcta agtctattcc
     8641 atctctatct gctttatccc tactaagctc gatatctaaa aaataaactc cactatctac
     8701 tttattatct tctaaatagt cagctacttc aatataacta ttagcttcca aagttatttt
     8761 aaactcttta tctttactgt cagcagaatc ttctaaagac caaatagcat atttaactaa
     8821 atcatgtatc cttctaactt gatccttctc atcgtcacaa ataataattc catattcttc
     8881 caaattaaac taccccttaa atactcataa ccataaggaa agtaaaccaa ccatctttaa
     8941 tttgataatt gataaaaata tcattataag gttgacttaa ttcttctata ttagctaatc
     9001 ctaatccatc atgattcttc ttagttgtaa aacccgattt tttcatatct tgaattgtta
     9061 agtctgtatt tcgacaacga ttcttaattt ctatttcaag ctcaccattc tctcgataaa
     9121 ccattgtatc tatcctagct tcatcgccaa gttcaagact ttcttcaatt gcattatcat
     9181 acgtaatccc taatattcta attatatcaa atgcattata ctcattcgat aaactatcta
     9241 tcacatcccg acattcaaaa gagtattgaa tattatcttg aaagattcta ttcaatttac
     9301 tgataaatag actctttaat aattcatctt taatgttgtc aacatcatta aactgccata
     9361 atactttatc ttctaagatc ttactcgaat attcagctag tttatctatt aactctttat
     9421 catgattttt ctttgcactg agcttcaaac ttactaacat attttggtag tcatgcttaa
     9481 atttgcgtaa acttcgctgg ctactttcta actgttgagt gtaaatcttt aaatctttaa
     9541 tttgctgtaa acttaattta tcttgtctaa tttttttact attattgtag atatatagtg
     9601 agaaaattaa ttgtacgata ataactacta ataatataag atataacacc ttatcaactt
     9661 taaataaata accagtcaaa taatatattc ctgcaaaact gactaataaa taaataatta
     9721 aatagaagaa tgtcttccca tattcatcat ctaaattctt tataatatct gttttcatta
     9781 aaatatagta ttctaaaata tttataacaa tagtgtctat tggaagtgcg ctgatgtatt
     9841 gtgaaattat ttgtgaaagt aaaaattcta tctcaaatga aagatatgaa tatagtagga
     9901 gaattaatat tcttcccaat acctgataat ctctttttct tcttttatat actatataaa
     9961 aagccgatac ttcaaaaagt tcggcacaaa aagcacctaa atctccacct ccatgataca
    10021 aaaaaactat cggaaatgta ataattgtaa atagaatatt ttgcttttta cttctattaa
    10081 tgggtgtaat taaatagaaa aatagatagt cacatgctac actaataaat aaaccaactg
    10141 catataatat aatattatat ctattatata tatccactat atctgtcatt ttacttgcaa
    10201 attcctaaaa atttaaacct acatacttta tcataagttt ttgttcctcc ctcttgttta
    10261 ccacctacaa taacttgtaa cttcttttct gttaacactt caaatttcat aaaaaatctc
    10321 tcctttgtta tctttattac aaatatagtt taacattttt taatctactt tattcgtttt
    10381 tatcatattc ggttcatttt aatgcttatt tggatgaaat tcttaaaact atagcctata
    10441 gccaccacat aaagtttaac acccatgcct cacataacct actttcttat tcttttctat
    10501 agctttctca tcaaatgact tgtaatgtct atcttctttt ttactagtat agatactgat
    10561 aaagataata tatacaacta ttactgtaac ctaaattatc atgtacttat ttcctaattc
    10621 ccaaaatata ttatattcta ttaaaaataa aagtagtgtc aaatttagct atatactata
    10681 acttacactt gacactactt gcagaaaaat agatctattt tctaattttt tatatttata
    10741 ttaatggcaa cttgcaaatc caccagaaat tccacccgct acggctgacc aaggtccacc
    10801 gatagctcca attaaagctc cacctacgat accagctcca cagtgaaccc agcgatttcc
    10861 gctaccacca taaccatttt taccaccatt tactgatgct aagttatctt cagtcataat
    10921 tgtgaatctt ttatctagat ttttcatttt aaatcactcc tatattataa acaagtaagc
    10981 gctccgccta ccattcctaa gtttgctcca cctacaatac cagctggtcc aagtggaact
    11041 cctgcagctg ctccagcaaa tagaccacct aagaagttac ctacacagtt aggtccacgt
    11101 ttcccaccat caacctttgc taattcacat tctgtcaata ctgtaaattc cttcatcatg
    11161 ataatcatcc tttcatatgt ttatttacct tcattgtagt atctaataaa taaagtagtg
    11221 tactaccacc tattagacaa aaaatagcaa ctattatcat tttaggcgtc tggatataat
    11281 ctaaataaga catgtcctca ttaccaaaca accatattcc tagtggaatc aatagtgccc
    11341 aaataactgg agcaataaca tatctcttct ttcctctaat gaatccacca tccaaccaag
    11401 tctcccatag tttttttagc atgtaaaaac acatccttcc taaaacactt gtgaaacata
    11461 tacttacact tttattgtat tatcattctg tattcaaata tcaatttagc gtaaaatacg
    11521 ttattctata cctagttggt tacatttctt tttaactaca aatattttga tttgaatgtc
    11581 tcaatctttt gaaaaatttg gtattagcga ttgtacatcc tatatcataa ccaaacttac
    11641 cactatctat atagtcataa gaatttcttc caccaattat atgtgccaat tctttcttat
    11701 caatttgtac aaaattatta ttcataactt caacacctca taatttttaa aaatttatta
    11761 tagctataat ttacacttat gattattcac ttcatctgct ctttttgatt atttcttcta
    11821 attttgctaa attttattct tattctcttt tttcaaccag ataggcacta tttattacca
    11881 aattggaaaa atctcctcaa tttattactt tctatgtaat aataaaaata cttttataat
    11941 gaattgaggt aaaaattatg aatagttttt ctaataatat taatttcagc aaaatttctg
    12001 tttcactaat tactttattc ctattgatct ggacattagt tgatggaaat ctaattcatc
    12061 ttggtatact agccttttct tctttggtta caaccatgct acatttccat tattttgaag
    12121 ctactgatga caagcatcca ctaaatagaa ttgattttgg attacaattg ctatttatct
    12181 ttatttctat tattaaattt ttcttgattt caggaagata acaataagcc tatcaggtat
    12241 caaattacat ctgataggct tatttattaa catatgtatc aacaattttg tacttctttt
    12301 taaattttct ttctgatata atttttcgat tagtgaaatc caagtaatcg cctatatacc
    12361 cacttgcata agttgcccac caacctgaag ctccattaaa taaagtctta aagttcgtcc
    12421 aagcactaat tttaacaggt gccttaactc cattcataat aaataacaat ttatcacctg
    12481 accactttag atagttagct ttaaatgctg cttttatcca ttcgggttgt tctgctgttt
    12541 tacttatctg ccatatttgt acttctttac ctttatagat tgctttcata gaaatcacct
    12601 tctacatata attaaagagc tctattaatt acatcttcat tatactattt tcataataca
    12661 tccaatgcta aatttcttaa ctagcactat ttcttactta tttggtaaat agtccaaata
    12721 agtagttatt gctaccattc cagcagttta tcacactatg tagacattat ttgcaataat
    12781 tacatatata cgattagggg gattgaaaaa atgagataca ttaaatttac tttactaata
    12841 tattcttttt tactaacttg gggaatcacc acgaatagta tatcagcgga tgaagttaca
    12901 cctactacaa catccgaaac aacagttacg cctcaaagtc aaagtacatc tgttgattct
    12961 aatgatgaag atgctgcaat tgaagaaaaa ttttactctc atgatgttac aatcgatgaa
    13021 tataatcaaa atgtggcaaa cttcaataaa gttaatactg atactgttaa aaccatggtt
    13081 actgaaaata gcaacaattt agaccaagtt ctttacattg gacgtcctac ttgttatttt
    13141 tgtcgacaag cttcaccaca cctacgtgat tttaatcaac taataaataa tcagctttac
    13201 tactatgata ttgatgctga acctagtgct catgactttg cgtttaaaga aattggaatt
    13261 cctggaacac ctacaactat gcgtttaaag aatggtaaag ttgtcagtgc ttggattggt
    13321 ggcgaaaaaa caggacaaga attttatgac tttttatttt ctgcagatgc taacaagtta
    13381 gcagattcct ataccataaa gaaaactgta agtgcaaata cttcaaatac tgttattaca
    13441 aataatcaaa atattaagcc aactattaag cctataccaa caaatataaa tcaacttaaa
    13501 gaggaaaaaa ctactcctga attagttaat actacttcac agtcatctaa acctgttaaa
    13561 aaagttcaga aacaaactac taataaagaa aataaaaatt ctgttctacc acagttaggg
    13621 gctgtccctc tttatcatca gccactattt aaacttccta ttccccgact tattcctaag
    13681 cgactagaac gtattatagc gttggtctct tttctagttc tatatattgg tatcactata
    13741 tggacagggt tgagtttaaa aaattgggat aaaaaataaa atatctaata tagcaatagg
    13801 accaattttt taatttatgt aaaattatcg ttttgattta gaaaaatcaa ttatttgcat
    13861 aaattttcta attggtccta tctttatatt taactttttt caaaatttgc aactttattt
    13921 ctcacattaa tttttgggac taacttcaaa taatatgctg tttactcttc agacactacc
    13981 cgatacttct tagcaaactt ttcggctgta acaaccttag aattggtaaa atcgataaca
    14041 tctccctcaa agccaatatc atacatcgcc gtgctgccac catttatact aacaagagaa
    14101 gctgaaatac cattcaaaat agttcgtatt attccttttt ttgccctagt aactgccggc
    14161 caataaattc tgactttatt accactacca tgcagccatc gcaacccatt atgctcaaaa
    14221 gcatctttaa cccaatcagg ctggacatta tctctactca cttgccaaac atctactttt
    14281 ctacctctat agattgcttt catttgcttt atcacctttc ttattacttt ttcctatcct
    14341 taatagccat aactaatcta tatatcacta atactatata taccaacagt gctattaata
    14401 ctattatata tagtatttta ttctcataac cttcatcaaa tattgtagtt actattagaa
    14461 atgttcctaa tgttgcttgc tttctagctc gtttatctaa ttcaccatgt tttttcttat
    14521 aattaacttt caaaattgct gatattataa aaaatatcca aataattgcc ttaataacta
    14581 aataatccat cattccacca cctattctct atttttgcca ttattatact attttaatta
    14641 aatttaattc tgtattttct taattaacac tcttttctgc ttatttggtt aacaacatat
    14701 ccatgtacgt tcaaaaaaat agcgacaaaa catcgctgtc ttgccactat tcccaactat
    14761 ttaaataaat taagttttgc gattctatca actgcttctt ctaaacgttc tggttcgatt
    14821 aacaaaccaa ttcgtacata accttcccca tattcgccaa aaccattccc aggagctact
    14881 gctactccag cttcatttaa aagcagatct gcaaattctt cactactata tccctttggt
    14941 acttccatcc aagcgtagaa cgttccctta ggtacaaaag ctttccatcc gattttttca
    15001 gcagcttgga tgaacgcatt tcttctagtt tcgtaacgat ctacaatctt attgatctca
    15061 gcatcgcgtt ctggagcttt caaagcatca atccctgcat attgtagagc tggaaagata
    15121 cttacaaata aatgatcttg gataagattt aaagcatcaa tgatatcagc atttcctacc
    15181 gcaaaagcaa ctcgccagcc tgccatgtta aaagtcttag agaaggtata aaattcgata
    15241 ccaacatcct tagctcccgg aatctccata aaacttaatg gtcgctctcc atcaaaacca
    15301 attgcaccat atgcaaaatc gctgatgata cctacttcat atttctttgc ccaagcaact
    15361 aattcttcgt aaaattctcg agttgcggtc gcacccgttg gattattagg gtagttaata
    15421 tagaagaatt tagcctttct agcaagttct tcaggaatag atttcaaatc tggtaagaaa
    15481 ttattctcct tcaaaagtgg aactttctca aaagttacct gtccaagtgt agctccagac
    15541 caataatctg gataaccagg atctggtaat aaaaatacat cgccaggatt catcaaagcc
    15601 agtggtagtt cgactaagcc cgttttagag ccaccaagaa ctgcaacttc tttttctgga
    15661 tcaaatgtag tttgatactt ttcttgataa aaatctgcca cagcttgttt aaaatctggt
    15721 tgtccacgaa ataatgagta cttgtgactt tgcggactag ctacccatct ttgtgtactc
    15781 ttgacgatat attcaggagt ttgtttatca ggattacctt gtcctagatt gataacatct
    15841 actccttctg caattttttt gttaactttg attaccaaat tagcaaagaa ttgctttggt
    15901 agatttttta gaatttcaga tttttcaaat ttcatcgtct ttcctcacct tcttagtcgt
    15961 ataattctgg tctgcgatcc tcaaatacat gaatttgttg tgtgaatttt tccattttag
    16021 atgtatctaa atcataaact gtcaatgttt cttgatcgcc actatcactt aaaacttcac
    16081 ctaaaggatt aattatcagt gaatgaccat taaatttatt gtcaggatta tcgcccactc
    16141 gattaaccgc aacaacata
//
