LOCUS       c00021_JAGSCY0..       16788 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAGSCY010000028.1 Lactiplantibacillus plantarum strain P8L800
            Scaffold28, whole genome shotgun sequence.
ACCESSION   JAGSCY010000028
VERSION     JAGSCY010000028
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-19 22:35:04
            Original ID  :: JAGSCY010000028.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16788
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16788
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6082:6788]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6083..6788
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..16788
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16788
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             2..106
                     /locus_tag="ctg21_1"
                     /transl_table=11
                     /translation="VKYCVTIEIRNSKLNLVIVKPPRLLSNLGGSLQQ"
     CDS             complement(185..529)
                     /locus_tag="ctg21_2"
                     /transl_table=11
                     /translation="MISDILSFTIFGSGAFQIAFLLTAFLGGFIDGLFLYRKSVNWLSV
                     VMTQILVMIFVSLMMDSWLISVLFGTNFKVLLLGRLARVIIQIPLQVIAIFYFIKALEK
                     RHVFDRMRLR"
     CDS             complement(928..1062)
                     /locus_tag="ctg21_3"
                     /transl_table=11
                     /translation="MIKSILKFCLAATLIVSGVLIGGTVLTAKGIDNLGDKLQDKLHG"
     CDS             complement(1079..1324)
                     /locus_tag="ctg21_4"
                     /transl_table=11
                     /translation="MHWLWVLIIGAIIGAIAGAITNKGKSMGWISNIIAGLVGSAIGEA
                     LLGSWGPQLAGMAIVPSIIGGVIVVAITSFVLTRMD"
     CDS             1610..3124
                     /locus_tag="ctg21_5"
                     /transl_table=11
                     /translation="VLAFKLCKSFLVIYVKRAIKMTEKLTTETGQPWANNEHSQTAGAR
                     GPVLMQDYNLLEKLAHFDRERIPERVVHAKGAGAKGFFELENDMGEYTKADLFNGVGKK
                     TPVILRFSQVAGEKGYPDTVRDVRGFALKFYTQQGNYDLVGNNTPVFFVNDPLKFPDFI
                     HSQKRDPKTNRRTQNMQWDFWAHSPESLHQVTYLMGDRGLPASYRTMNGYGSHTFKWVN
                     QNGEQFWVKYHFISDQGVKNMTAQAAEKAMSQDLDYLQDDLYDAIQEKNYPSWTMYVQI
                     LPYEEGLNYKWDIFDVTKVISHKDYPLIKVGKLTLNENPTNNFTDIEEAAMSPANFVPG
                     IEPSPDKLLQGRLFSYKDAQRYRLGANFEDLPVNKPVVPVHNYERDGYMKINNQGAEVN
                     YEPNALHGPEEVPDAALSPDSVRGETRAQPYRYQVDYTTQAGDLYRLMSEPEQERLINT
                     IKDALGQVTLPGVKKLEIKQFYEADKNYGTRVANALGMNIADIISD"
     CDS             complement(3282..3719)
                     /locus_tag="ctg21_6"
                     /transl_table=11
                     /translation="MIRLYTQSSCHSSRVARQWLEAHGIEFKEKNFSVDSPTVQDLKRI
                     LSLTEHGVDDIISARSKDYPEIAPKLPEMPLNEALKLLCDHPKLLRRPIIISDSKIQVG
                     FNEDDIRQFIPRPVRRLKFNALLSRLDGNTGDHIINKRMVE"
     CDS             complement(4075..4818)
                     /locus_tag="ctg21_7"
                     /transl_table=11
                     /translation="MISVYICEDDPKQLQQIRQIITKVIVDQQLDMSICLACQDPHELL
                     DKVNAQQPQKAIYVLDIALNSDINGIQLASQIRDMGRRSKIIFITTHTELSLMVFQYQV
                     EALDFILKDFPDSLYERFSKVLHVAQDRFQTDENDQDDYVQIKIGETVRSINVKSIIFF
                     ESSTSPHKIVVHLDDGELEYYGLLKDVPDLSPNFYRCHKSYVVNLKRIKSLDKHLRRLT
                     MTNGEKVLCSAQANRYLAKWLAKKS"
     CDS             complement(4811..6073)
                     /locus_tag="ctg21_8"
                     /transl_table=11
                     /translation="MLMIVFQELSIYLIIKSLLRNIFFVRLFDVIFLSVCMLMSYIFLA
                     KLGISFSFLMLMMFIFFTWWYVRVLSGALCITFQVFIWSIMVDHICDILTRLMKVPNGY
                     VVVFVILSVVSLIFLNIVMDRTNFSPTFSNQSLNRITALLLMIIYLYIMLSEGLENQFQ
                     VILSNLIILSVVMGLVLVIYNEYLKNVRAKYEVQKQRIQIQNDTRYMNEIEAHYNELRR
                     FRHDYQNMLISIDEYLKTDDLEGLQEYYQKNLAPVSNRVLKEKYNLEDLSRVKVKSIKS
                     ILFSKLSYAQSQEIEVHFDLKEPLIDITVNELDLDIALGIMLDNAIEASVGHADGEIMS
                     AIFIEKNSTVFLIQNNVFEQLPPLWKLKEAGYSTKGKNRGIGLNSLSKIVNRNENMILE
                     TRVLGAVFLQRLTVKRVSQND"
     CDS             complement(6083..6211)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_9"
                     /sec_met_domain="TIGR04223 (E-value: 2e-08, bitscore: 25.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEKMYKVLSHLFQYVGTKQLVMCCHGILFETKIPDELKSKD"
     CDS             complement(6192..6788)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_10"
                     /sec_met_domain="AgrB (E-value: 1.6e-35, bitscore: 113.1,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKPEQKLLLYKLSDRLFAAIQKNLQLERRQALLVKLGIDTVLNV
                     IPKLIITIILALLLHELVPVLVFMGSFLVLRGFAYGRHLKSDLLCTILTIFVFVGVPYV
                     IETGISEVYRLLLSLIFVIIISIFAPADTVKNPITSKSLRKKLKRRAIGLSLILSLLQI
                     VSNNYFGTIILIAMALAALLLMPYERRENYERKNV"
     CDS             complement(7156..9270)
                     /gene_functions="other (smcogs) SMCOG1223:ATPase (Score:
                     962; E-value: 4.5e-291)"
                     /gene_kind="other"
                     /locus_tag="ctg21_11"
                     /transl_table=11
                     /translation="MANFYGNDPFFNNDMDDVFNQLFRRMDNQNSERARYLVNGQSLTP
                     DEFAQYRATGKLPQNNKTIEVSKDGKQAVKKGGILEKLGTNLTEQARDGLLDPVIGREN
                     EIQETAEILSRRTKNNPILVGDAGVGKTAVVEGLAQAIVAGKVPETIQDKEIYSIDLSS
                     LEAGTQYRGSFEENIKQLVKEVKAAGNIILFFDEIHQIIGTGATGGEDGGKGLADIIKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNDVVINEPTAADTLRILQGVKKLYEKH
                     HHVVLPDDVLKAAVDYSIQYIPQRTLPDKAIDLIDMTAAHLAAKNSQTDVETLDQRVKK
                     LEATKEAAVKSEDFTKAADIKKSIEETKQKIKKTDQKEKITATIDDVAQSVERLTGIPV
                     ADMGANDIEHLKNLDKRLKSKVIGQDEAVEMVAKAIRRNRAGFSEGDQPIGSFLFVGPT
                     GVGKTELAKQLALDMFGNKNAIIRLDMSEYADRTAVSKLIGTSAGYVGYEDNANTLTER
                     VRRNPYSIVLLDEIEKADPQVLTLLLQVMDDGRLTDGQGNVINFKNTIIIATSNAGFGN
                     EALSGDKQRDQSLMDKLAPFFRPEFLNRFNGIVEFSHLTKQDLSQIVDLMLADVQKTLA
                     KKSIKLEVTKAAKDWLMEQGYDEAMGARPLRRVIEQQIRDKVTDFYLDHLDVKNLKADL
                     VDAEIVISAA"
     CDS             complement(9661..9894)
                     /locus_tag="ctg21_12"
                     /transl_table=11
                     /translation="LSVENNYCKLQQAHDQKCRVSLRFYKTNGQMAETVGYVTTIVPKA
                     IAFMAITGHRHLIQLNRIITVSLQSQDRRYVM"
     CDS             complement(10531..10887)
                     /locus_tag="ctg21_13"
                     /transl_table=11
                     /translation="LLAIGAGAQGIYVSNHGGRQLNGGPASFDVLHEIAQAVNGRVPTI
                     FDSGVRRGSHVFKALANGADLVALARPIIYGLALGGAQGVASVVSHLNDELLIDMQLAG
                     TKTIEDVKRAKLLR"
     CDS             complement(10900..11631)
                     /locus_tag="ctg21_14"
                     /transl_table=11
                     /translation="MTVINGYEQSDREQKLTILNLPSLEAAAKKIIPSGGFGYISGGSE
                     DEWTLKQNTMAFNHVQIVPRALTDMEQPSTQTQAFGIDLKTPIMMAPAAAQGLAHARGE
                     AATAEGMAQVGALMAQSTYSSTSIADTAAAGKGAPQFFQLYMSKDWNFNQSLLDEAVKA
                     GAKAIILTVDATVDGYREADIINNFQFPIPMANLTKFSEGDGKGKGIIEIYAAAAQKIS
                     PADVRRITEYTNLPVIVKGIQ"
     CDS             complement(11658..13412)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 471.4;
                     E-value: 6.8e-143)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_15"
                     /transl_table=11
                     /translation="MEMTKIKAGQALAQVLVDWNIDHIYGITADSINNTVDGFYQEKDH
                     LKYIQVRHEEVGALAAAADAKLTGTIGVSFGSAGPGAVHLLNGLYDAKMDHVPVLALVG
                     QSATSIMNTNFFQEMNQDPIFADVAEFHKQVTTAEQIPYVVDEAIRSAYATRSVSVVII
                     PDDLSGQDIEFDGFKTASLSGSQQVLMPKLDDVQQTIAALKAAQHPVLWIGKGAYNARQ
                     EVIAVSEKFSLPVLSTAPATGIMPTDHPNFMGSRGRLGTKPAFEVSQAADLVLFVGTNF
                     PFARYLPQGIKFIQVNNNLADLGKQHDADITVLADAKEFFQALLQSEVTIKPTKFLKAA
                     QRDKQNWNRWLKTIATDDQGGLTAEGVLEAIKDNATDDAVFGLDVGNNTEWAIRQLPLN
                     KQQTFTMSAWYGTMGFGLPAGLAAQLNYPKKQVWSISGDGGYAMVMPDLLTEVKYHLPV
                     INVVLENKVLGFIQHEKLLANQAPYGIDLIGADWAKMADNMGAIGFKVTNLKELKATFQ
                     KVTQLQQNGNQLPIVIDAKIKNVDPIDTSFVPVDPENFDADTIAKYRERYGIAEADQPA
                     LSQLLNEL"
     CDS             complement(13494..13919)
                     /locus_tag="ctg21_16"
                     /transl_table=11
                     /translation="MANTQLSDATHIMAYIALHTDDQLKSEHIASSLNTDPTMVRRMMS
                     KLRKAGLLTSVRGVARPTLACSPNDITLKDIYVAVVAKRNFLNVDHNTSETCPVGSVIP
                     RVMEKYYCDIQNSAEARMSRVTLQDIIDDISAVQQQA"
     CDS             complement(14092..15903)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 494.2;
                     E-value: 8.6e-150)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_17"
                     /transl_table=11
                     /translation="MVMKQTKQTNILAGAAVIKVLEAWGVDHLYGIPGGSINSIMDALS
                     AERDRIHYIQVRHEEVGAMAAAADAKLTGKIGVCFGSAGPGGTHLMNGLYDAREDHVPV
                     LALIGQFGTTGMNMDTFQEMNENPIYADVADYNVTAVNAATLPHVIDEAIRRAYAHQGV
                     AVVQIPVDLPWQQIPAEDWYASANSYQTPLLPEPDVQAVTRLTQTLLAAERPLIYYGIG
                     ARKAGKELEQLSKTLKIPLMSTYPAKGIVADRYPAYLGSANRVAQKPANEALAQADVVL
                     FVGNNYPFAEVSKAFKNTRYFLQIDIDPAKLGKRHKTDIAVLADAQKTLAAILAQVSER
                     ESTPWWQANLANVKNWRAYLASLEDKQEGPLQAYQVLRAVNKIAEPDAIYSIDVGDINL
                     NANRHLKLTPSNRHITSNLFATMGVGIPGAIAAKLNYPERQVFNLAGDGGASMTMQDLA
                     TQVQYHLPVINVVFTNCQYGFIKDEQEDTNQNDFIGVEFNDIDFSKIADGVHMQAFRVN
                     KIEQLPDVFEQAKAIAQHEPVLIDAVITGDRPLPAEKLRLDSATSSAADIEAFKQRYEA
                     QDLQPLSTYLKQFGLDDLQHQIGQGGF"
     CDS             complement(16274..16660)
                     /locus_tag="ctg21_18"
                     /transl_table=11
                     /translation="VYCMMTKERIIFSTKVLEIGAESADFKSIGMAVLFGDEAPDALRP
                     SCFIIEVVPISEQITAGMKLEVDNQVYQITAVGGEVQTNLGRLGHTAISFTGAKEAKLP
                     GTLYVEQGDYPDFKVGSVVRIIAE"
ORIGIN
        1 cgttaaatat tgtgtcacaa tagaaatccg taactctaaa ttaaatttag tcatagtaaa
       61 acccccgaga ttgttgtcca atctcggggg ttcacttcag caatagaaaa gttagactta
      121 tttgtttaac gattgtagcg cgtttcatac cgtgttcaac ctctttttgt agcatccatc
      181 gatattatct aagcctcatt ctatcaaaaa cgtgtcgttt ttctaacgcc ttaatgaagt
      241 aaaaaatagc aatcacctgt aatggtatct gaatgatgac gcgtgccaat cttcccaaca
      301 ataacacttt aaaattagtg ccaaatagca ctgaaattag ccatgagtcc atcatcaaac
      361 taacaaaaat cattacaagt atttgcgtca tcacaacgga taaccaattg actgatttac
      421 gatataaaaa caaaccgtca ataaatcccc ctaaaaatgc agttaacaaa aaggcaatct
      481 gaaacgcgcc ggaaccaaaa atagtaaagc ttaatatatc ggagatcatc tccaagagac
      541 caccccaaat gggaccatat agataaccaa tacaagccat agacaaaaag ccaaaagata
      601 attgaaaata cgctggtccg atagcaattt tgtataaaat aacgtctaag gccaataaga
      661 aagccgatgt agtcagcact aataaattca tttttggcaa ctgaaaaaca tttttcgcaa
      721 taagtttaga cataggccaa tcctcttttt ttgattttaa tcataccctc attcttaata
      781 aaagtaaata ttacttttat tcgattgaag gtagtttaaa atcgtcgctc ttgatttagt
      841 tccttgaact caatgatatt actcatacta aaagccacta acaggtcaac tagtacaccc
      901 atcagtggct cattgtaaaa ttaattttta tccatgtaac ttatcttgta atttatcacc
      961 caagttatca attcccttag cagtaagtac ggtcccacca ataagaacac cacttacgat
     1021 taaggttgca gctaaacaaa actttaaaat gcttttaatc atcgcaatca tctccttact
     1081 aatccatccg tgtcagaaca aatgaggtta tcgcaacaac aatcacacca ccaataattg
     1141 aaggaacaat tgccattccg gctaattgtg gtccccatga tcccaaaaga gcttccccaa
     1201 ttgcagatcc aaccaatccg gcaataatat tactaatcca ccccatcgat ttacctttat
     1261 tagtaatagc acctgcaatt gcaccaataa tagcaccaat gatcaaaacc cataaccaat
     1321 gcataaaatc cctcctagac ttattaaacc gcttaaatac aataatagaa ttacacgaat
     1381 atttaagccg attcataaat gattacttct tataattatc attttacaat tatcgataat
     1441 gatagacaaa tataacacat tatttaataa atgggtcgct actatttctc atgtgacgat
     1501 tccgggtggc ctagaaaata tcaaacagct tgatagctga ttaaaattaa actacgccac
     1561 atgaacgatt aacttaactg tgcataatga ttgaagtcac tctgttaagg tgttagcgtt
     1621 taaattgtgc aagagctttc ttgtaattta cgtgaaaagg gcgattaaaa tgacggaaaa
     1681 attaacgacg gaaaccggcc aaccatgggc taacaatgaa cattcccaaa cggcaggagc
     1741 tcgtggtccc gtattaatgc aagactataa tcttttggaa aaactagccc attttgatcg
     1801 tgaacgaatt ccagaacggg tcgttcatgc taagggggcc ggagcaaaag gtttttttga
     1861 acttgaaaac gacatggggg aatatactaa ggcagactta tttaatggtg tcggtaagaa
     1921 aactcccgta atcttaaggt tctcacaagt tgccggtgaa aaaggttatc ctgacaccgt
     1981 tcgagacgtg cgcggttttg ccttaaaatt ttatactcag caaggcaatt atgatctcgt
     2041 tggaaacaac acaccggtct tttttgtaaa cgacccttta aaatttcctg acttcatcca
     2101 ttcacaaaaa cgggatccta aaacgaaccg tcgtacgcaa aatatgcaat gggatttttg
     2161 ggctcattct ccagaatcat tgcaccaggt cacttattta atgggcgacc gaggtcttcc
     2221 tgcgtcctat cgaaccatga atggttacgg ttcccatact tttaaatggg ttaatcagaa
     2281 tggcgaacag ttttgggtta agtatcactt catctcagac caaggcgtta aaaatatgac
     2341 tgctcaagca gctgaaaaag caatgagcca agatttagat tacttacaag atgacttata
     2401 tgatgcaatt caagaaaaaa attacccatc atggacgatg tatgtccaaa tcttgccata
     2461 tgaggaaggt ctaaactata aatgggacat ttttgatgtc actaaagtca tctcccacaa
     2521 agactatcca ctaattaaag tcggcaaact aactttaaat gagaatccca ctaataactt
     2581 taccgatatt gaagaggcgg ccatgtcgcc agcaaatttt gttcctggta tcgaaccatc
     2641 tcccgacaaa ttactacaag gtcgcctatt ctcctataaa gatgcacagc gatatcggtt
     2701 aggtgccaac tttgaagatt tacccgtgaa caagccggtt gttccagttc ataattatga
     2761 acgtgatggt tacatgaaaa ttaataatca aggtgctgag gtcaactacg agcctaatgc
     2821 actgcatggg ccagaagagg tgccggatgc cgcactttca cctgattctg ttcgtggtga
     2881 aacacgcgca cagccttatc gctatcaagt tgattacaca actcaagcag gcgacctata
     2941 tcgcttaatg tcagaacccg agcaagaacg cttaattaat actatcaaag atgcgttagg
     3001 ccaagttact ttgcctggtg tcaaaaaact cgaaatcaag caattttatg aggccgacaa
     3061 aaactacggt acacgcgtgg ctaatgctct gggaatgaat attgctgata ttatcagtga
     3121 ttaatatttt gaccggatgt tatccagcgc gatattattt ttgttataaa gaatgatgat
     3181 gccgtctcat ggttattaac taaagagcga caggttagac tcatatcgtg taagtctagc
     3241 ttgtcgctct ttaattaaca aaaaatctta gatatagctt actactcgac catcctttta
     3301 ttaataatgt gatcccctgt attaccatct agacgactca acaatgcatt gaactttagt
     3361 cgccgaactg gtcgtggaat aaattggcga atatcatctt cattaaagcc aacttgaatt
     3421 ttactatcac taatgatgat aggccgacgt aacaacttcg gatgatcaca caacaattta
     3481 agtgcctcat tcaatggcat ttcgggtaac ttaggcgcaa tttcaggata gtctttagat
     3541 cgagctgaga taatatcgtc tacaccatgt tcggttaaac tcaaaatacg ttttagatct
     3601 tgcaccgtgg gcgaatcaac actaaaattt ttctccttga actcaatccc atgtgcttcc
     3661 aaccattgcc gtgcaactct agaagaatga cagcttgatt gtgtatataa cctaatcatt
     3721 cctaatctgc ccctctctcg ttaaaattca tcacagcgta ttgatcgaca ttaacttctg
     3781 cctgtcacaa catcctttaa actaaacgca ttcgttactg tcatgaccaa tccaataccc
     3841 cgtgaacaca tctttattat aggctctgaa caagggacat accgaccgtt ttaagacgaa
     3901 taatctgagg ataatcgttt taagtacact tttaaacggt ttaggaaaga acgaacccag
     3961 tacacgtaat gctaacaaat atcactgcaa tttctaatcg aataacgctg aattttcatc
     4021 gcgtagcaca taaaaagtcg cctactaatt taacaggcga cttccttgga actattatga
     4081 ctttttagca agccatttag ctagataacg attagcttgt gcagaacaaa gcactttttc
     4141 accatttgtc atggttaatc gtcgcaagtg cttgtccaat gacttaatgc gtttcaagtt
     4201 aacaacatat gacttatgac acctatagaa attaggactc aaatcaggaa cgtcctttaa
     4261 cagtccatag tattctaatt caccatcatc caaatggact acgattttat ggggactggt
     4321 tgaactttca aaaaatataa tgcttttaac attaattgat ctgaccgtct caccaatttt
     4381 tatttgaaca tagtcgtctt ggtcattttc atcggtttga aaacgatctt gcgccacgtg
     4441 taaaaccttg ctaaatcgct catacaagga atctggaaaa tccttaagaa taaaatctaa
     4501 tgcctcaact tgatattgaa acaccatcaa agataactcc gtgtgtgtcg tgataaaaat
     4561 aatcttgctg cgacggccca tgtcacgaat ctggctagct agttgaatac cattaatatc
     4621 tgaattaagg gcaatatcta acacatagat tgccttttga ggctgctgtg cattaacctt
     4681 gtctaacaat tcgtggggat cttggcatgc taaacagata ctcatgtcta gctgttgatc
     4741 gacgattacc ttagtaatga tttgccgtat ttgttgtaat tgtttcggat catcttcgca
     4801 aatgtagaca ctaatcattc tgagatactc gcttcaccgt caagcgttgt aagaataccg
     4861 ctcctaagac tctggtttcg agtatcatgt tctcattgcg attaacaatc ttacttaaac
     4921 tattcaatcc aatcccccga ttcttgccct tagtggaata acctgcctct ttcagcttcc
     4981 ataagggtgg taactgttca aaaacattgt tttgaatcaa gaacaccgta ctattttttt
     5041 cgataaaaat ggcactcata atctctccat cagcatgtcc taccgatgct tcgattgcat
     5101 tatccaacat aatccctaat gcaatgtcta aatccaattc attaacagta atgtcaatta
     5161 atggttcctt taaatcaaaa tgaacttcaa tctcttgcga ttgtgcatag ctcaacttac
     5221 taaataggat actcttaatc gacttcactt tgacccgact caaatcttca agattatatt
     5281 tttcttttaa cacccgattt gaaaccggtg caagattctt ttgataatat tcttgtaaac
     5341 cttctaaatc atcagttttc aaatattcat ctatcgaaat caacatattc tgatagtcat
     5401 gtctgaaacg tcgcaactca ttatagtgag cttcgatttc attcatatag cgagtatcat
     5461 tttgtatttg tattctttgc ttttggactt catatttggc tcttacattt tttaaatatt
     5521 cgttataaat caccaatact aaccccatta caactgacaa tataattaaa ttacttaata
     5581 taacctggaa ctgattttcc agaccttcac tcaacataat atacaagtat attatcatta
     5641 ataatagtgc ggttatgcga tttaagctct gattactaaa cgtgggactg aaattcgtgc
     5701 gatccattac aatattaaga aaaattaagc ttacgacact caatatgaca aacactacca
     5761 catacccatt aggaactttc attaaacgag ttaatatatc acaaatatgg tcaaccataa
     5821 tcgaccatat gaacacttga aatgttatac atagtgcacc gcttagaact cgtacatacc
     5881 accaagtgaa aaatataaac atcattaaca ttaaaaaaga aaaactaatt cctaactttg
     5941 ctaaaaaaat ataactcatc agcatacaga cggataagaa tataacatca aaaagtctca
     6001 caaaaaatat atttctcaac aaagatttaa ttatcaaata gatagataat tcttggaaga
     6061 caatcattaa catatatcta cactaatcct tgctttttaa ttcatcagga attttagttt
     6121 cgaataatat cccatggcag cacataacca actgtttagt acctacgtat tgaaaaagat
     6181 ggctaagtac tttatacatt ttttctttca taattttccc tcctttcata gggcattagt
     6241 aataaagcgg ctaatgccat cgcaattaaa atgattgtgc caaaataatt attactaact
     6301 atttgtaaca aactcaaaat taatgacaat ccaattgccc gtcgctttaa tttttttctc
     6361 aatgacttcg atgtaatagg attctttacc gtatcagctg gagcaaaaat acttatgatt
     6421 attacaaata ttaaacttaa taacaatctg tatacttcag aaataccagt ttcaatcaca
     6481 tacggcacac ccacaaacac aaagatagtt aatatcgtac ataacaaatc cgatttcaag
     6541 tgacgtccat aggcaaagcc acgcaaaact aaaaaactac ccataaaaac taacactggg
     6601 accaactcgt gtagcagcaa cgctaagata atagtaatta tcagcttagg aataacattt
     6661 aatacagtat caatgcctag tttaactagt aatgcctgcc gtctttctag ttgaagattc
     6721 ttttgaatcg cagcgaataa ccgatcgctt aatttataaa gcaatagttt ttgttctggc
     6781 ttttccatat cccactccta taatgctcaa atacatacct gtatcaacag tttaaaacag
     6841 tattaattaa ttgaaaagaa tacataaata tattaattat tcaatattgt tttaagacta
     6901 gaaataaaca tttaaagata catcagttta attattcata cgaaactaaa gtttcatgta
     6961 aaaagatcgt taatataaat cagtttcatc gatactcccc cttaattttt ccttagatta
     7021 caagtcaaac tagacttaat ttcactaatt cacattactc aatagattaa tatcaaatgg
     7081 tgaaaatcaa cgaaaagagg agatctatca agcaatctcc tcttacataa agttatttat
     7141 gaacactgat ttaagctaag ctgccgatat cacaatctca gcatccacta aatcagcctt
     7201 caagtttttg acatctaagt ggtcaaggta gaaatccgtt accttgtcac gaatttgttg
     7261 ttcaattact cgccgtaatg gccgcgcacc catcgcttca tcatagcctt gttccatcag
     7321 ccaatctttg gccgctttag ttacctcaag tttgatggat tttttggcta acgttttttg
     7381 tacatccgcc aacatcaaat cgacaatttg acttaagtct tgcttagtca gatgtgaaaa
     7441 ttccacgatt ccattaaaac ggttcagaaa ttctgggcgg aaaaatggtg ctaacttatc
     7501 cattaatgac tgatctcgtt gcttgtcacc acttaatgct tcattaccaa agccagcatt
     7561 agaagtagcg ataataatcg tatttttgaa attaatgaca ttgccttgtc catccgttaa
     7621 gcgcccatca tccatcactt gtaacagtaa cgttaatact tgtggatcag ccttttcaat
     7681 ttcatctaat aatacaatgg aatatggatt acgccgaacc cgttcggtta gagtattagc
     7741 attatcttca tagcctacgt atccagccga ggtaccaatt aatttcgaca cagctgtacg
     7801 atcagcatat tcactcatat ctagccgaat aatcgcattt ttatttccaa acatatctaa
     7861 ggctaattgc ttagctaatt cagtctttcc tacgccagtt gggcccacaa acagaaaact
     7921 tccaattggc tgatcaccct ctgaaaagcc cgcacggtta cgccgaattg ccttcgctac
     7981 catttcaacc gcttcatctt gaccgattac cttacttttc agacgcttat caagattttt
     8041 caagtgctca atatcattag cgcccatatc agcaactggt ataccagtta aacgttcaac
     8101 cgattgtgcc acatcatcaa tcgtggcagt gattttttct ttttgatccg tttttttaat
     8161 tttttgcttg gtttcctcga tcgacttctt gatatcagcg gcttttgtaa agtcctccga
     8221 tttaacggcg gcctccttag ttgcctctaa ttttttaacg cgttgatcca atgtctcaac
     8281 atcagtttgc gaatttttag ccgctaaatg agccgcagtc atgtcgatca aatcgatagc
     8341 tttatctggc aaagtgcgtt gtggtatata ttggattgaa taatccacag ccgccttcaa
     8401 aacatcatct ggtaatacaa catgatgatg cttttcgtac agctttttaa caccttgtaa
     8461 tatacgtaaa gtgtcagcgg ccgtcggttc attaatcaca acatcattga atcgccgtgc
     8521 caaagccgca tttttcaaaa tagtattgcg atattcatct tgagtcgtag ccccgattac
     8581 agtcagctcg ccacgtgaca aagcaggttt aatgatatca gccaatcctt tgccaccatc
     8641 ttcaccacca gtggcgcccg tgccgataat ctgatgaatt tcatcgaaga atagaataat
     8701 attaccagct gctttaactt cctttactag ctgtttaata ttttcttcaa aagaaccgcg
     8761 atattgagtt cctgcttcca aagacgataa atcaatcgaa tagatttctt tatcttgaat
     8821 cgtttctgga actttaccag ccacaattgc ttgtgccaga ccttcgacga ctgcagtttt
     8881 acctacacca gcatcaccaa ctaagattgg attatttttc gtcctacgac tcaaaatttc
     8941 tgcagtttct tgaatctcat tctcacgtcc aatcactgga tctagtaatc catcacgagc
     9001 ctgttccgtc aaattagtcc ctaacttttc taaaatcccc ccttttttaa cagcctgttt
     9061 accatcttta gatacttcta ttgttttatt attttggggt agcttaccag ttgctcggta
     9121 ttgagcaaac tcatccggtg tcagcgattg tccattaact aaataccgtg cacgctccga
     9181 attttgatta tccatgcgcc gaaataattg attgaaaaca tcatccatat cattgttgaa
     9241 aaaaggatca tttccgtaga aatttgccat attacaacac ctccataaaa atttatatgt
     9301 gtaacttagt gaccataata tcctttaaaa ctacaactga atcgtatcac gatttttatg
     9361 tatcgttaag taaagtgctt atagaatcaa ttagaaataa ttagaataat tttgtttaaa
     9421 caaaagagaa atcaatttca taaaatgaat tgatttccct acaaggttcc ctatttaata
     9481 gcccttgata aagaacttga attaacaagt tactttccag accaatttta atttaagaga
     9541 ctgcgactca aaaagcacac ccagtatcaa gttaaggcca actagttatc gttaatattg
     9601 ccacttaaat atcaatacta gcaatcatga tacacgtgta aaatcataaa ccaaaacata
     9661 ttacatgacg taacggcggt cttgggactg taaactcaca gtaatgattc tattgagttg
     9721 gataaggtgc cgatgaccag taattgccat aaatgcaatt gctttcggta caatcgtagt
     9781 gacatagcca actgtctcgg ccatctgccc atttgtttta taaaaccgta atgagactcg
     9841 acatttttga tcatgcgctt gttgtaattt acaataatta ttttcaacac tcaaattaaa
     9901 gtctcccgtt caaagaattc aggtttattt attcgtcagt gaatctatgt gtttgttttt
     9961 ctcattgttg acggcgtaag tccacattaa ggagtcagct attcagtaaa aactaaataa
    10021 ctagtattca tgttcagctc agtataatat gcattgatgg ttactaatca aaaatcgatc
    10081 tctaaatatc ctaattacta tgaaactttg aagttaattt atgagaaaaa taactcacaa
    10141 caaaactcat gattacaacc ttgtcatcat aactagatta tgaaacattc agcctcctaa
    10201 ataaaactgg tatgcgcgca tgtgcgcatg tgtacagtat actattgcca ggtatgtctg
    10261 aataaccgtt ttaagacttg aaaaactcag ctgggtgctt taggacgctt tttgtgcatt
    10321 ttaagacaat atcctaactt caacgccggc atagcttcaa ttcgtcaatc agtgtcttag
    10381 ttcctcagct atttctgttc agaacatctt cctattacaa taaaaagcgt tgatctcagc
    10441 agaatttact tccaccaaaa ccaacgctaa agtgttatta tatcaggtat tttaaattca
    10501 tttcagacat tatattcagc attacttcta ctacctaagt aatttagcac gtttaacatc
    10561 ttcaatcgtc ttagttcccg ctagttgcat atcgatcaac agctcatcat taaggtgact
    10621 cactacggaa gcgacaccct gcgcaccacc caatgctaat ccatagataa tcggccgagc
    10681 aagtgccacc agatctgcac cattggctaa cgccttaaag acatgggagc cacgccgaac
    10741 accgctatca aaaattgttg ggacgcgccc attaacggct tgcgcaatct cgtgtaaaac
    10801 atcaaaggaa gctggaccac catttaattg ccgaccgcca tggtttgaaa catagatacc
    10861 ttgagcacca gccccgattg ctaacaaggc atcttctggt tactgaatcc ccttcacaat
    10921 aactggtaaa ttcgtatatt ctgtaatacg ccgaacatca gctgggctaa tcttttgcgc
    10981 cgcagcagca tagatttcta tgataccttt ccctttacca tccccttcgc tgaacttagt
    11041 caagttagcc attgggattg gaaactggaa attgttgata atatcagctt cacgataccc
    11101 gtcaactgtt gcatcaacag tcaaaatgat tgccttagca ccagccttca ctgcttcatc
    11161 caataaactc tgattgaaat tccaatcctt gctcatatat aattggaaaa attggggcgc
    11221 acctttacca gctgcggcag tatccgcaat tgacgttgaa gaataagtac tctgagccat
    11281 gagtgcccca acttgagcca tcccttcagc agtcgcagct tcaccccgtg catgtgccaa
    11341 tccttgagcg gccgctggag ccatcataat aggcgttttg agatctatgc caaaagcctg
    11401 agtctgtgtg cttggctgtt ccatatccgt caatgctcgt ggcacaattt gaacatggtt
    11461 aaaggccatt gtattctgct ttaaagtcca ttcgtcttct gacccaccac taatatagcc
    11521 aaagcctccg ctcgggatga tctttttagc agctgcttcc aatgatggta aatttaaaat
    11581 cgttaacttt tgctcacgat cactctgttc atatccatta ataactgtca ttatactaat
    11641 ctcctttaca taacccttta taattcattt aataattggc taagtgccgg ttgatccgct
    11701 tcagcgatac catatcgttc acgatactta gcaatcgtat ctgcatcaaa gttttctgga
    11761 tctactggaa caaaactagt atcaattgga tcaacatttt taatttttgc atcaatcaca
    11821 attggtagtt gattaccatt ctgctgtagt tgagtaactt tctgaaacgt tgctttcaac
    11881 tctttaaggt tagtcacttt aaaaccaatc gcacccatgt tgtctgccat cttggcccaa
    11941 tcagcaccaa tcaagtcaat cccatacggc gcctgattag cgagtaactt ttcatgttga
    12001 ataaagccta atactttgtt ttctaaaacc acgttaatga ctggcaaatg atatttaact
    12061 tccgttagta agtctggcat caccatggca taaccaccat caccagaaat actccaaacc
    12121 tgcttcttag gataattcaa ttgggcggcc aaacctgctg gcaaaccaaa acccatcgtg
    12181 ccataccaag ccgacatcgt aaaagtctgt tgcttattca atggtaactg tcggattgcc
    12241 cattccgtat tattcccaac atccagacca aagacggcat catcagtagc attgtcttta
    12301 atagcttcta gcaccccttc agccgtcaac cctccttgat catcagtagc aattgtcttg
    12361 agccaccggt tccagttttg cttatcacgt tgagcagctt tcaagaactt agttggctta
    12421 attgtcactt cggattgaag taatgcttgg aaaaattctt ttgcatctgc aagaacagta
    12481 atatcagcat catgttgttt gcctaaatct gctaaattat tattgacttg aataaactta
    12541 attccttgtg gcaagtaacg tgcaaatgga aagttagtac caacaaacaa aactagatct
    12601 gccgcttgcg agacttcaaa ggcgggttta gttcctagtc gaccgcgaga gcccatgaaa
    12661 ttaggatggt cagttggcat aataccagtt gctggagccg tcgacaaaac cggcaaacta
    12721 aatttttcag aaactgcgat aacttcttga cgcgcattat aggcaccctt gccaatccat
    12781 aaaacagggt gttgagcagc tttcaaagcc gctatcgtct gctgaacgtc atctaatttc
    12841 ggcattaaga cctgttgact gccgctaagt gaagccgttt taaaaccatc aaactcaata
    12901 tcttgaccag acaaatcatc tggaataata acaacagaaa ccgaacgggt cgcgtatgct
    12961 gatctaattg cttcatcaac cacgtatgga atctgttcag ccgttgtcac ttgtttatga
    13021 aattcggcta catctgcaaa aattggatct tggttcattt cttgaaagaa gttcgtattc
    13081 ataatggatg ttgctgattg accgactaaa gctagcaccg gtacgtgatc catcttggca
    13141 tcgtataatc cgttcaagag atgaacggcg cccggtcctg ctgaaccaaa gctaacacca
    13201 atcgtcccag ttaatttagc atctgccgcg gcagctaaag caccaacttc ttcatgacgt
    13261 acttgaatat acttcaagtg gtctttctct tggtagaacc catctaccgt gttattaatc
    13321 gagtcagctg taataccata gatatgatca atgttccagt cgactaacac ttgtgccaat
    13381 gcttgtcctg ctttaatttt agtcatttcc attaccctct ttttgttgtt acttttttga
    13441 gcacaactat atcctaaata aaaacttgac ccttgtcaag tctttatctt aaattatgct
    13501 tgttgttgaa cagcgctaat gtcatcaata atatcttgca gcgtcactcg cgacatacgt
    13561 gcctcagcac tattctgaat atcacaatag tatttttcca tcactcgcgg aattaccgac
    13621 ccgaccggac acgtctccga agtattatga tcaacgttta aaaaattacg cttagccacc
    13681 actgctacat agatatcttt caaggtaata tcattgggcg aacaagctaa tgttggtcta
    13741 gcaacgccac gaaccgaagt taacaagcct gcttttctta acttactcat cattcttctg
    13801 accatggtag gatccgtatt taaactacta gcaatatgct cacttttcag ctggtcatca
    13861 gtatgcaacg caatatatgc cataatatgc gtcgcatcac ttaattgtgt attagccatc
    13921 tagacacctc ccatatccat ctctattgtt acttatttta gcacatctaa catgaacata
    13981 aaagcgatta aggaaataag ttaggcttct ttccctaatc gcaacataag attatttgat
    14041 aatctccatt aattcaatca aacttattca agacatcgat agtagctgaa tttaaaaccc
    14101 accctgtcca atttgatgtt gcaaatcatc taagccaaat tgttttaaat aagttgaaag
    14161 tggttgtaaa tcttgagctt cataccgttg tttaaatgct tcaatatcag ctgccgaact
    14221 cgttgccgaa tctaaacgaa gcttttcagc aggcagtggc cgatctcctg taatcaccgc
    14281 atcaatcaga actggttcat gctgagcgat tgctttggct tgttcaaaaa catcaggtaa
    14341 ttgctcaatc ttattaactc gaaaagcttg catgtgcacg ccatcggcaa tcttactaaa
    14401 atcaatatca ttgaattcaa cgccaataaa atcattctga ttagtatctt cctgctcatc
    14461 tttgataaat ccatattggc agttggtgaa aacaacatta atcactggta aatggtattg
    14521 aacttgcgtc gccaaatctt gcatggtcat cgaagcgcca ccatcaccgg ccagattaaa
    14581 cacctgccgc tcaggataat taagtttggc agcaattgct cccggaatac caactcccat
    14641 cgtagcaaat aagttagaag taatgtgccg attggacggc gttaatttca aatgtcgatt
    14701 cgcattcaaa ttgatatcac caacatcaat cgaatagatt gcatcaggct ccgcaatttt
    14761 attaaccgca cgtagcactt gatatgcttg taaaggccct tcctgcttat cttctaatga
    14821 agctagataa gcccgccaat ttttaacatt ggctaaattg gcttgccacc aaggtgtcga
    14881 ctcccgttca gatacctgtg ctaaaattgc agccagcgtt ttttgtgcat cagcaagtac
    14941 cgcaatatct gttttatgtc gtttacctaa cttagctgga tcaatatcaa tttgtaagaa
    15001 ataacgcgta tttttaaacg ctttggaaac ttctgcaaac ggataattat taccaacaaa
    15061 taaaacaacg tcggcttgcg caagtgcctc attcgccggt ttttgtgcca cccgattagc
    15121 agaacccaaa taggctggat aacgatccgc gacaataccc ttagctggat acgtactcat
    15181 taatggaatt ttcaacgttt tactcaattg ttcgagttct ttaccagcct tacgagctcc
    15241 aatgccatag taaataagtg gccgttcagc tgcgagtaaa gtctgtgtca atctcgtcac
    15301 tgcttgaacg tcgggttctg gtaataacgg cgtttgataa ctattagcgg aagcatacca
    15361 atcttcagct ggaatctgtt gccatggtaa atcgactgga atttgcacaa ccgcaacacc
    15421 ttggtgcgcg taggcgcgtc gaattgcttc gtcaataaca tgtggcaacg tggcagcatt
    15481 gacggctgtt acattataat ctgcaacgtc cgcataaatc ggattctcat tcatttcttg
    15541 gaacgtatcc atgttcatcc cagtagttcc aaattgacca ataagtgcta gaacagggac
    15601 atggtcttca cgcgcatcat ataacccatt cataagatga gtgccaccag gtcccgctga
    15661 gccgaagcaa accccgattt tacccgttag cttagcatca gcagcggcgg ccattgcacc
    15721 aacttcttca tgccgtactt gaatataatg gattcgatcc ctttctgctg ataatgcgtc
    15781 cataattgaa ttaattgaac ctccaggaat accatacaaa tgatctactc cccaagcttc
    15841 taaaacttta ataactgctg cacctgctag tatgttagtt tgttttgttt gtttcataac
    15901 cataataaag cccccatttc atgcacaatt taattacgca caatttaata aacgaatatt
    15961 accatagcaa acgcttacat tcaagtggtc ataaactcat gctttttacc acttaatcac
    16021 gattcaaacg cattgtagat caacaacagc gctagtctgc ttgccttgat gaaccaccat
    16081 cgctgttgac agttagtatc tcatacattc attttttaaa caattttagt aattagtgta
    16141 tgttttacag gggcatactt ccaacaatgt ctgcatgttt agaagctagc cattcttcga
    16201 aaactaacta ccgctttcaa aacatgacct taactcaact cgacacagag caaaataaca
    16261 tctgccaagt taattattca gctataatcc gtaccacgct accaacttta aaatcaggat
    16321 aatcgccctg ctcaacatat aacgtcccag gcaatttagc ctcctttgca cccgtaaaac
    16381 taatagccgt atggcctaat cttccaaggt tagtctggac ttcaccacca actgctgtaa
    16441 tttgatagac ttgattgtcg acttcaagtt tcattcctgc tgtgatttgc tcacttattg
    16501 ggacaacttc gataataaag caagaaggcc gtaatgcgtc tggagcttca tcaccaaata
    16561 atactgccat gccaatcgat ttaaaatcag cagattccgc acctatttct aagacctttg
    16621 ttgaaaagat aattctctct tttgtcatca tacaatacac ctcaaacctt ctaaaaattt
    16681 attttgaata taatccaaaa cttgcaatcc aagcaataaa gacccgcgga acgccgttga
    16741 taaaccgact atataacact gatggcaccc caacttcaac cgtcttag
//
