LOCUS       c00080_JAGZLH0..        6797 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAGZLH010000080.1 Streptococcus thermophilus isolate
            L3_131_368G1_dasL3_131_368G1_concoct_3_sub
            L3_131_368G1_scaffold_2950, whole genome shotgun sequence.
ACCESSION   JAGZLH010000080
VERSION     JAGZLH010000080
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 01:10:25
            Original ID  :: JAGZLH010000080.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6797
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6797
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3557:6449](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(3558..6449)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..6797
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6797
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             complement(681..1889)
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 278.7; E-value: 1.3e-84)"
                     /gene_kind="transport"
                     /locus_tag="ctg80_1"
                     /transl_table=11
                     /translation="LNKKEQQNTYLLVGSRIISRVGDIMFDFANNTFLSSVNVKSLMLV
                     GIYQTLENIISVIFNLFGGVLSDNFQRKRIIILTDILSGVLCLALSFISNQQWLIYAVV
                     ITNIILAFFSSFSGPAYKAFTKEVVEADNISKLNSLLESFITVVKVVVPLVSVSLYGLL
                     GLYGILRLDGITFIASGLLILFIRPILEESTGKQVFSLSKIFSDLFEGGRYLASQKEIL
                     YLVILSAIVNFFLAAYNLLLPYSNQMFPRVTVGLYGVFLGAEAVGGLIGASLSSILNKV
                     LKIKTMILYLGVSGVFLSLTPMVYCVFPSAYMLALYPALFNLFLTMFNLQFFSYIQKNV
                     DNVFLGRVFGIIFTVAILFMPIGTMTFTFLLSPKNIFNFVIVGLSIGGISLLFYRIFSK
                     RLR"
     CDS             complement(1915..3561)
                     /locus_tag="ctg80_2"
                     /transl_table=11
                     /translation="MSIYKDIVEGYQLNNIQEKDKLNNVLVQLNEKDDQEMINRKNFIG
                     HFTASAFVISKDNRRLLMVHHNILKRYLQPGGHIDKNDRNPLDAAKRELFEETGIDSEI
                     LTYQCAEPLNSLIPFNVSVHKIPENKLKNERSHYHYDLQYLFYIENEVDVKIDSNESSS
                     YEWIQLDNVKDMDGYKEIIKKIEKLEAASQERFLSNMLKGASFEDISCITVQHIIPSTI
                     PIIMTLQKIFGHRLLVCAKPNSVDKMVWHKLENMGVRLTLASRDEYFNVDYLGIKSKTI
                     LLDIGGYFASIAQIPNLPIECIIEDTENGIQKYENVIDQIEYPLFSVARNPLKKNEDYL
                     VGADIVFGTDYILHQKNLLMQYMQVVCIGYGKIGYGICTKLRELGIRPKVLEKDSMRTI
                     QAVRDGCDILLEKDFKNIDLIFCATGSKSLDILDFRSIKDGTFLVSATSSDDEFNYSYL
                     LDEYEEIVETSLITRYESEDNYFYLLNQGTPTNFVVNSALGNYILLVQAAILYTAKKFI
                     EDREMAIAKQVNTLSDEDNYNIAKQWLEEFC"
     CDS             complement(3558..6449)
                     /NRPS_PKS="Domain: AMP-binding (6-388). E-value: 6.9e-65.
                     Score: 210.9. Matches aSDomain:
                     nrpspksdomains_ctg80_3_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     172.4; E-value: 2.1e-52)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_3"
                     /sec_met_domain="AMP-binding (E-value: 9.9e-65, bitscore:
                     206.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.5e-07, bitscore:
                     20.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILKTFSDTVKQYPSKVAVMYSGGEFTFQEVDVMSNFIAKQLLL
                     NSDEETVPFYIEKNKYVLPVVLGIMKSGKIPLPITNSLEVKISLERISEVVFDVLISDR
                     DVKLENHSVTLLLLPKKLESYSEYQEVATTKENEIAHIICTSGTTGVPKKVFLTDDNID
                     WLVKEFYKIVKFTSESKFLFTTPYTFDVSLTEILAPVYTGGTLVCYDGGIQNIIRLGET
                     IEKKKITHLSLSPSFAETIIDISGPEVFQNLRALCLAGETFPSSLANRLRGLIQQGCRV
                     FNLYGPSETTIYATYYELKDRKYNTVPIGKPLPGVQLKIASQKENSKMAELLIGGNGVT
                     EGYRLQPELNKAKFKLIGSNRYYVTGDYVYYQGDNLVFSSRIDSQVQVNGIRIELDEVK
                     SIVDKLKSVKSSRVVFYKKKLVVFYEADLNIKEDIIRGLPSYLNPTVVKVESYYLNQNR
                     KLDVPKMLEIYYYKKQSQQGDDVRKNILDVLSKFERVDITDLDSLELVRFYLEIEDIFD
                     IEIKENDFYRLKSVDSIVDYIRNKSFFQERSTEPNDSFTKEHDLVNLEYNLTKMNYRYL
                     KNIITPSPTQKRLYKNNQNRVIGFNLALEEVTYLELNKLHHIIKYLSYKIDIFRLVVEK
                     EQTRFSIGIVNEGDYSPNIIVLNNLPTELELQGILDNIEVIPIPIIVVGTRDKKVRFYF
                     PYHSIDASSLNKLGDTVYQLYEKKIVIDEVPSSSLVAFSQFKREVLQNDVSGDVLARLP
                     KIKPAIEFEKLNDEVQCFQVSLPEDIKGDDVYLFTIYAISQCILSDYNLSAISGGLSLD
                     FRDYEQFDAYDLIGDIHKKIPFQVNRTETFEEFKNSHFKILEIYRTGIDYYEIAMLGND
                     MSAKEVQERLNNLSLSINFIGEAFRLKDTINNIIDVDFDKNFINVFVHERFAYAVIKSE
                     LLSNSVYDLMHKDSKFELKVIDKKRLENEETNR"
     CDS_motif       complement(4629..4676)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg80_3_0004"
                     /evalue="1.30E+01"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg80_3"
                     /protein_end="607"
                     /protein_start="591"
                     /score="-0.8"
                     /tool="antismash"
                     /translation="NNQNRVIGFNLALEEV"
     CDS_motif       complement(5256..5312)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg80_3_0003"
                     /evalue="2.60E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg80_3"
                     /protein_end="398"
                     /protein_start="379"
                     /score="20.0"
                     /tool="antismash"
                     /translation="SRIDSQVQVNGIRIELDEV"
     aSDomain        complement(5286..6431)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg80_3_AMP-binding.1"
                     /evalue="6.90E-65"
                     /label="ctg80_3_AMP-binding.1"
                     /locus_tag="ctg80_3"
                     /protein_end="388"
                     /protein_start="6"
                     /score="210.9"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FSDTVKQYPSKVAVMYSGGEFTFQEVDVMSNFIAKQLLLNSDEET
                     VPFYIEKNKYVLPVVLGIMKSGKIPLPITNSLEVKISLERISEVVFDVLISDRDVKLEN
                     HSVTLLLLPKKLESYSEYQEVATTKENEIAHIICTSGTTGVPKKVFLTDDNIDWLVKEF
                     YKIVKFTSESKFLFTTPYTFDVSLTEILAPVYTGGTLVCYDGGIQNIIRLGETIEKKKI
                     THLSLSPSFAETIIDISGPEVFQNLRALCLAGETFPSSLANRLRGLIQQGCRVFNLYGP
                     SETTIYATYYELKDRKYNTVPIGKPLPGVQLKIASQKENSKMAELLIGGNGVTEGYRLQ
                     PELNKAKFKLIGSNRYYVTGDYVYYQGDNLVFSSRIDSQVQV"
     aSModule        5286..6431
                     /domains="nrpspksdomains_ctg80_3_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg80_3"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(5388..5459)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg80_3_0002"
                     /evalue="2.80E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg80_3"
                     /protein_end="354"
                     /protein_start="330"
                     /score="19.7"
                     /tool="antismash"
                     /translation="ELLIGGNGVTEGYRLQPELNKAKF"
     CDS_motif       complement(5976..6032)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg80_3_0001"
                     /evalue="1.00E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg80_3"
                     /protein_end="158"
                     /protein_start="139"
                     /score="15.1"
                     /tool="antismash"
                     /translation="AHIICTSGTTGVPKKVFLT"
     CDS             complement(6639..6797)
                     /locus_tag="ctg80_4"
                     /transl_table=11
                     /translation="LFADNQKDLQKFVNKRLEELQKDGTLAKLAEKFFGNKDYIPTKDA
                     LKVPSKK"
ORIGIN
        1 tttattgtaa cagaattcac taagcttaac taatacttaa acataatcaa agtgataaga
       61 aaatactatc acctaaaaat atcaattgtt tgacaaagag ccgaattgct tcgtctttct
      121 gaacgcagac gggttgtctt aaacgacatg gtagctctag ctcagccttt accagagtat
      181 gacatcttac ggtcaattcc tggcatcgca gaaaccacag cgacatctat cattggcgaa
      241 ttgggagata ttcgtcgcag tataccaatc aaatcaacgc ttttattggc attgacctga
      301 gacactatga atctgggaac tttctcgcta aggaacacat cactaaacga gggaatccct
      361 atgccagtaa aatcttgttc aagtacattc acaacatcgc ttcagctagt cataccaatc
      421 cctgcaatat cgctgacttt tatgagaaac gaacaagaca tttagagcta tttctaaact
      481 aatcggcgac ccatctactg tctctaaaaa agtatgtaaa caccttacca tcaaggaatc
      541 aatcaacact caaaatgtga ggcccgccca cttctaaaac gattacctta tgtgtgtaat
      601 ggttgcccta acaagtatat aaattgtgac tttactaagc aattttacta cgccatcgga
      661 gctaaaatta ctctgaaaat ttacctcaat cttttgctaa aaatcctata aaagagaagc
      721 gaaatacctc ctatagataa accaacgata acaaaattaa agatattttt agggcttaaa
      781 agaaaagtaa atgtcattgt cccaatgggc ataaataaaa ttgcaacagt aaaaataatc
      841 ccaaaaactc taccaagaaa gacattatcc acattctttt ggatatatga aaaaaactgt
      901 aagttgaaca tagtcaaaaa caagttgaat aaagcaggat ataacgcaag catataagca
      961 cttggaaaaa cacagtatac cataggtgtc aaagatagaa aaacacctga tactccaaga
     1021 tataaaatca ttgtttttat tttcaaaact ttattgagaa tactgcttaa agacgctcca
     1081 ataagaccac ctactgcttc tgctcctagg aaaacaccgt ataagccaac ggtaactctt
     1141 gggaacatct gattgctata tggtaacaac agattataag ctgctaaaaa gaaattaaca
     1201 atcgcagata aaataaccaa gtacaaaatt tccttttgac tagctagata ccttcctcct
     1261 tcaaaaagat ctgaaaagat tttcgataat gaaaacacct gtttcccagt actttcttca
     1321 agtatgggac gaataaagag aataagcaac ccagatgcaa taaatgttat cccatctaga
     1381 cgtaaaatac catataatcc tagtaaaccg tatagagata ccgataccag gggaacaacg
     1441 actttaacta ccgttataaa cgattctagt aatgagttta gttttgaaat attatctgct
     1501 tccaccactt ctttagtaaa agccttataa gcagggcctg aaaatgatga gaaaaaagct
     1561 aatataatgt ttgtgataac cacagcataa atcaaccact gctgattaga aataaaagat
     1621 aaggcaagac acaatactcc gcttaaaata tctgttaaaa tgataatccg ttttctttga
     1681 aagttatcag acagaacacc accaaaaaga ttaaaaatca cactgatgat gttttctaat
     1741 gtctgataaa taccaactaa cataagtgac ttaacattta cactcgataa aaaagtgtta
     1801 ttcgcaaagt caaacataat atctccaaca cgagaaataa tacggctccc tacaagtaaa
     1861 tatgtatttt gttgttcttt tttattcaaa ataaactcct ccgatatttg ttcattagca
     1921 gaactcttct aaccattgct tcgcaatatt atagttatcc tcatccgaaa gagtgtttac
     1981 ttgcttagct atagccattt ctctatcttc aataaacttc ttagctgtat atagaatggc
     2041 tgcctggact aataaaatat aatttcccaa agcggagttt actacaaaat tagttggtgt
     2101 tccttgattt aacagataga aatagttgtc ttcactttca tatctagtga ttaatgaagt
     2161 ttcgactatt tcttcatatt catccaataa atagctataa ttaaattcat catcactaga
     2221 tgttgcagag actaggaagg ttccatcttt gatagagcga aaatctaaaa tatctagact
     2281 ttttgaaccg gtcgcacaaa aaatcaaatc aatattcttg aaatcttttt ctagcaaaat
     2341 gtcgcaacca tcacgtaccg cttgaatagt tctcatgcta tctttttcca gcaccttcgg
     2401 tctaatacca agttctctta atttggtaca gatgccgtaa ccgattttcc catatccaat
     2461 acaaaccact tgcatatatt gcattaataa atttttttga tgtaatatat aatctgtccc
     2521 aaaaacaata tccgcaccaa ctaagtaatc ctcattcttc ttcaggggat ttctagcgac
     2581 agaaaataac ggatattcta tttgatcaat aacattctca tatttttgaa tcccattttc
     2641 tgtatcttca atgatacact cgataggtaa gtttggaatc tgagcaattg aggcaaaata
     2701 cccaccaatg tctaataaaa ttgttttact ctttatcccc agataatcta cattaaaata
     2761 ttcatccctt gaagctaatg ttaatcttac ccccatattt tctagcttgt gccataccat
     2821 cttatcaaca gagtttggtt tagcacacac taacaaacga tgcccaaata ttttttgcaa
     2881 tgtcatgata atcggtattg tacttggaat aatatgttgt acagtaatac atgatatgtc
     2941 ttcaaacgat gcacctttca gcatattaga taaaaaacgt tcttgagaag ctgcttcaag
     3001 tttttcaatc ttcttaatga tttccttata gccgtccatg tcctttacat tatctagctg
     3061 aatccactca taggaactcg attcgttgct gtcaattttc acatcaacct cattttcaat
     3121 ataaaataaa tattgcaagt cataatggta gtgggaacgc tcattcttca atttattttc
     3181 tggtatctta tgcacagaaa cattaaaagg tatcaagcta ttcaatggtt ctgcacattg
     3241 atacgtcaat atttcagaat ctatcccagt ctcctcaaac agctcacgtt tcgctgcatc
     3301 tagcgggttt ctatcatttt tatcaatatg ccccccaggc tgtaggtatc tttttaaaat
     3361 attatggtga accatcaata aacgcctgtt atcttttgaa ataacaaatg ctgatgctgt
     3421 aaaatgccca atgaaattct ttctatttat catctcttga tcatcttttt cattaagctg
     3481 taccaaaacg ttattcaatt tatccttttc ctgaatatta ttcagttggt acccctctac
     3541 tatatcttta taaatactca tcggtttgtc tcctcatttt ccagtcgttt tttatcaatt
     3601 acttttagct cgaatttgct atctttatgc attaagtcat aaacactatt actcaataac
     3661 tcagatttta taactgcgta tgcaaatcgc tcatgtacaa atacattaat aaaattttta
     3721 tcaaaatcaa catcaattat attattaata gtatctttta acctaaatgc ttcgccaatg
     3781 aaatttattg atagagacag attatttaat cgttcttgca cttctttagc actcatatca
     3841 tttcctaaca ttgcaatttc atagtaatca atacctgtac gatagatctc caaaattttg
     3901 aaatgagagt ttttaaactc ctcaaaagtt tcagttcgat ttacttggaa tggaattttc
     3961 ttgtgaatgt ctcctattaa gtcatacgca tcaaactgtt cataatctct aaaatccaaa
     4021 gatagacccc cagatatagc agacagatta tagtcgctta aaatacactg tgagatagca
     4081 taaattgtaa aaagatatac atcgtctcct ttaatatctt ctggtaaaga aacttgaaaa
     4141 cattgaactt catcatttaa tttctcaaac tcaatagcag gctttatctt tggcaatcta
     4201 gcaagaacat ccccagagac atcattctgt aacacctccc ttttaaactg cgaaaaagca
     4261 accagtgaac tactaggtac ttcatcaata actatctttt tttcgtacag ttgatatact
     4321 gtatctccaa gtttatttaa tgatgatgca tcaatagaat gatatggaaa ataaaatctt
     4381 acttttttat ctcttgttcc caccacaata attggaatag gaatcacttc tatattatct
     4441 aatattcctt gtaattctaa ctctgttggt aaattattta gtacaataat attaggtgag
     4501 taatctcctt cattcacaat acctatgcta aatcgagttt gctccttttc gacaacaagt
     4561 ctaaatatat caattttata gcttaaatat ttaataatat ggtgcagctt attcaattct
     4621 aaataagtca cttcttccag tgctaaatta aaaccaataa cacgattttg attgttttta
     4681 taaagtctct tttgtgtcgg gctaggagta ataatatttt tcaaataacg ataattcatt
     4741 tttgtgagat tatactctaa attaaccaag tcatgttctt tagtaaaact atcgtttggc
     4801 tcagttgaac gttcttgaaa aaatgattta tttctaatat agtccacaat cgaatctaca
     4861 ctctttagcc tataaaaatc attttcttta atttcaatat caaagatatc ctcaatctct
     4921 aaataaaatc taactaattc taacgaatcc aaatctgtga tatcaactct ttcaaattta
     4981 gatagtacat ctaaaatatt ttttctaaca tcatctcctt gttgactttg ttttttataa
     5041 taatatatct caagcatttt tggaacatcc aactttctat tctgattgag ataataactc
     5101 tcaactttaa ctaccgtcgg atttaagtaa ctaggtaaac ctctaataat atcttcttta
     5161 atattcaaat cggcttcata aaatacgaca agtttcttct tataaaaaac aactcgtgat
     5221 gatttaactg atttaagttt atctacaata gattttacct catctaattc aatacgaata
     5281 ccatttactt ggacttggct atctattctt gaactaaata ccaagttatc tccttggtaa
     5341 taaacgtagt cccccgttac atagtaccta tttgaaccta tcaacttaaa cttagcttta
     5401 tttaattcgg gttgtagtct atacccttcc gttactccat taccaccaat tagaagttct
     5461 gccatcttag aattctcttt ttgagaagct atctttagtt gaaccccagg caaaggctta
     5521 ccaattggaa cagtattata ttttctatct ttcaactcat agtaggttgc ataaattgtt
     5581 gtttctgaag gcccatataa attaaatact cgacaccctt gctgaataag ccctctcaac
     5641 ctattcgcta atgaactagg aaatgtctca cctgctagac acaacgctct taaattctgg
     5701 aatacttctg gcccactaat atcaataata gtttcagcaa aagacggaga taatgataaa
     5761 tgagttatct tctttttctc aattgtttct cctagtcgaa taatattctg aatcccacca
     5821 tcgtaacaaa ccaaagtacc acccgtatat acaggtgcca aaatctctgt taatgaaaca
     5881 tcaaaagtat agggagttgt aaataaaaat tttgattcgg aagtaaactt cacaatttta
     5941 taaaattctt ttacaagcca atctatgtta tcatcagtta aaaatacttt tttaggaacc
     6001 ccagtagttc cagaagtaca gataatatgt gcaatttcat tctctttagt tgtagctact
     6061 tcttgatact cactgtaact ttctaatttt ttgggtaaga gcaaaagagt tactgaatga
     6121 ttttcaagtt taacatccct atcacttatc aacacgtcaa agacaacttc gctaatacgt
     6181 tctaatgata ttttgacctc aagactattt gttataggta acggaatttt acccgatttc
     6241 attatcccca aaacaactgg taaaacatac ttattttttt ctatataaaa aggtacagtc
     6301 tcttcatcgc tattgagtag tagctgctta gcaataaaat tagacatcac atctacttct
     6361 tgaaaagtaa actctcctcc gctatacata acagcaactt tagaaggata ttgtttcacc
     6421 gtatcactaa aagtttttaa tatggtcatt tctcttctcc ttaatttgat tgattatgca
     6481 ctgtcattca taatttatcc acacacaaca ataagaattt caaaagcaat tttcaaagtt
     6541 ggcaaaaatt ttaccttttt catcatttcc ctcttttatt tatcatataa taaacaaagg
     6601 cttttcgtca ccgactacag ttgacaaaag agactttctt attttttgct tggaactttc
     6661 aaagcatctt tagttggaat ataatctttg tttccaaaga atttttcagc caacttagcc
     6721 aaagtaccat ctttttggag ttcttccaaa cgtttgttta caaatttttg aagatctttt
     6781 tgattatctg cgaacaa
//
