LOCUS       c00021_JAGZHR0..       17608 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAGZHR010000002.1 Lactobacillus gasseri isolate
            L3_129_093G1_dasL3_129_093G1_maxbin2.maxbin.012
            L3_129_093G1_scaffold_31, whole genome shotgun sequence.
ACCESSION   JAGZHR010000002
VERSION     JAGZHR010000002
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 01:49:20
            Original ID  :: JAGZHR010000002.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 73735
            Orig. end    :: 91343
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17608
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[78735:86343]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..12608
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..17608
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..17608
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(1070..1795)
                     /gene_functions="regulatory (smcogs) SMCOG1136:GntR family
                     transcriptional regulator (Score: 135.8; E-value: 3e-41)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg21_81"
                     /transl_table=11
                     /translation="MAQSKVSAIAQDLVDKIKHQQYKPGEYLPSEHQLMDLYGASRETI
                     RKALTNLTDLGLIQKIRGKGSIVLNLDRYAFPISGISSFAELNNQLGLKAETKVLLLQK
                     EDHLPTGFIKYFPEEKNSAGFHLERLRLIEGQADVLDCDYLLSPPINSLPKDAAKTSIY
                     NYLENKEKLEISYATKEISVCTVNQRIQDLLQLDNELAVLVASRNYLADTTKFELTLSY
                     HRPDKFKFVDFARRKKIKF"
     CDS             1989..3344
                     /locus_tag="ctg21_82"
                     /transl_table=11
                     /translation="MVQDTTNLLAPATGAVIALAKTSDPIFSQGTMGDGFGLTPTVGKV
                     VAPVSGKISMVADTKHAVGIVTNEGLEVLVHMGVDTVGLKGAPFTIKIENGQEVKAGDE
                     IAEMDLDEIKAKGLDTTIMVLITNSADKISGLDVTEGEAKAGEVVATAYLKTSETEDTS
                     SKKLSYPELAAFIIKNVGGKDNVNNVIHCITRLRFYLKDESKANDDVLKNQRGILDVMH
                     ASGQYQVVIGNEVTNVFDEVVKQLGPLDSEAAPAPEDDGKNPVSKAFGNLIGFITGSMS
                     PIIGVIAAAGIIKGILALLTLPQLGSLLSIKSTAYITTSAIADSAFFFLPVLVGYCAAK
                     RLNSDPIIAAVIGGVLVYPQLVEWGKAFKTMFEVGGIKFEFLNYTYSIFPMILAAWLAK
                     KCEDWLKKWLPSYLQMIFIPLITVLVVSALTLMVTGPIIQGVANGIAVFINW"
     CDS             3399..3917
                     /locus_tag="ctg21_83"
                     /transl_table=11
                     /translation="LVIFGLHWGVVPLVAQQIAGTGESALNAIICSSMIAQGAAVLAVA
                     IKSKKEDLKELGFASTISAMCGVTEPAVYGISLRYKKVFISGCIGSAFGGLVTGLMHGT
                     MYGFTGGLIGFSSFFNPKHPTDLSSFYTFLIASAVTIVVSFIVTWVWGYNDSMVQGAKV
                     AKKKRPGSK"
     CDS             4060..4854
                     /locus_tag="ctg21_84"
                     /transl_table=11
                     /translation="MIFEKLFSKENKKDEIVDVKLTDKEFNKLKIKLGVGDVIIEQGEN
                     FSVSFKGKKHYLPLLQLSDGKLQLKQKISLLETGEAELKIVIPQEVTLDSLDIQTNSGN
                     IEIVDTKAEKAYLKSTEGRVRVRRVAIAESLLESTDGNVTVRNSDLADGKLATYDGEIK
                     VSGSTLSRVVLNVTDGDMNLTDVTIDEGSANLKAGNFTLDHAVFKSDYEIKNIEGNNTV
                     WRANLKYARVRTANGQNNISFDPQSSGVVLSMTTVDGDNVVE"
     CDS             5001..5240
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_85"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 6.1e-11,
                     bitscore: 36.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKLSSLELKKIAGGGRRQIVGQCAKNIGFGAAIGAAAGSVKGVA
                     FGLEIGAVGGAVLGANMGAIKGAITCGGMVIGRR"
     CDS             5247..5360
                     /locus_tag="ctg21_86"
                     /transl_table=11
                     /translation="MKKLNKNELGMIKGGTNWGAVGSFATQNIKFPKRKKR"
     CDS             5357..5815
                     /locus_tag="ctg21_87"
                     /transl_table=11
                     /translation="MKNNIFEKIYGTKLNLTLEEKEEVLEKSIQLGRILYIIEFLLLFG
                     VYFIFFFDAKLAFWLFLSINVVILYLIIPFEIALLRRKHKLVITYQTKGDKIKDIFLTT
                     VFFALISVAITIYFNWTKNHMVYIDLPTLIGIIIGSLLLGLTFTHPNK"
     CDS             complement(5853..6488)
                     /locus_tag="ctg21_88"
                     /transl_table=11
                     /translation="VQSKRPIIIGIAGGSGSGKTTIAHEIYDQLQQDDHILIMTQDSYY
                     KNNDDLSMSERKKINYDHPDAFDMPLLVEQLRQLMNYKAVEMPVYDFTAHTRSEKTIHT
                     EPADIIILKGILVLGEENLRNLMSIKVFVDTDDDIRFIRRLERDTQERGRSVHSVIDQY
                     LKTVKPMYNQFIEPTKRYADIIVPEGGENDVAIDMLTTKIRSVLNTVK"
     CDS             6650..8017
                     /locus_tag="ctg21_89"
                     /transl_table=11
                     /translation="LTVQEKAAIRNWNPRYRRNVYLYLWIYGILGAVTGITNDAALSYF
                     DIVAPGLISGLNIFNAITALLMSLMIIWVHELGYRKILLILPPLTSIFLALTTITTNQI
                     VIMFAYIISWTAIGVYDLMYPLMWTSYVPKEIRTKMFTVVMVVNLVAQTILTFIGGKAV
                     VYFFSKMQGIPYDTASNLSAHTAQLSGSYLANYTNAFRIVLILTALVNVVAFILAIFIK
                     DEPKDYRTVGMKKPQTPEEKKKAFEALINKKTIMWILYIAGIQLGARLVVPYIPIYLND
                     YLHIPRGITSTINTFQTAAMFIGYFFAPFLAKKLGAIVSIAAGTLTCAPLMFLMANGRH
                     FGTGITLFVIVGVLLFLRSGLANATMPIQQEVQMIIVDKDMRPAFTAVVQIAYAVIGII
                     DGLFTAFYLLKTPAGYANAYYIATALYVVVSILLIVMFAKQYNWILDEKKSTSNEK"
     CDS             8158..8310
                     /locus_tag="ctg21_90"
                     /transl_table=11
                     /translation="MMKDIRKENIVKATTLSEEEMIEVVGGKAVNGFIVPSSICKGIKW
                     WKFGR"
     CDS             8311..9642
                     /locus_tag="ctg21_91"
                     /transl_table=11
                     /translation="MTELYLLAILVSILLDIVLFYKVTKLKVSKAHFLFYLLLVIIGVI
                     CSFTGYKAILFYNVLAIVILNIIHKDNNNLTLISGTLIYIFSVDLIIELLRGVSLDVIE
                     KFNMSKNEIEWINLGCIFCFFLITYLIVFFSANWIRKKLTGNNFRIFFWLILYLYLVTL
                     VIAVVYKGTKNIPPATIFFLSFLIVQFIFSLGLYYLMVKNQKVLLKKSEQDKIIQEQEQ
                     LQEYTKYLEESEDELRAFRHDYRNMFNSLKISAQEGNTKEVIQKLDEYTKANLNAKAFE
                     KYRDVNHIKIKSLKSLIIAKLTEMYREHIPYNFECSSEITKLPKNINEIDLVRIVGISC
                     DNAIEESKVLIEQNQEAHIEIMAYSSERGEFEYEIQNKRSDSEISIKQIQQSGYSTKKS
                     HSGLGLANINSIKNKYENMTISYEVPEGYFDFYLVIEPEEESEE"
     CDS             9639..9929
                     /locus_tag="ctg21_92"
                     /transl_table=11
                     /translation="MKYSVIVCDDDEVLAKNLAKNIKYAVSNFTDDNPVYENIEINLEL
                     VATTFEQVVSYVVANDIQNAIYFLDIELSQNSEAKNGVDLAEFIKKQDPNA"
     CDS             10032..10436
                     /locus_tag="ctg21_93"
                     /transl_table=11
                     /translation="MQRLEETLTGAVQSINNLMKSGRKELIYKIGRRVNKVEDTTIYYL
                     ENSTSQHKVNLITETGVAEFRSNISKINEENDFLVKVSQSCVVNPNNINSIDFSKKTIK
                     FPNGDEVVFARSCRKTVEDLLNKYPEINVK"
     CDS             10449..12608
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 334.3; E-value:
                     2.4e-101)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_94"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1064.0,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 4.9e-45, bitscore:
                     146.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLFKYKSVYVPQVDEMDCGVACLAMILKQYHSRVSLAHLRHEART
                     NLEGTTALGLVKTAQKFNFKTEAVKADMSLFDENSIQYPFIVHVLKQGELLHYYVVLKN
                     AKNYLVIADPDPSVGVIKMPKDRFAQEWTGIALFMVPNEDFEPIKEKKNNLWSLFPYMF
                     KQKRLMINIILAALLMTIISICSSYFVQGIIDTYIPDGTYQTLSILAVGLLIAYVFNSI
                     FSYGQNFLLNILGQRLSIDLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALA
                     STVISLFLDLSIVIVMGLVLAAQNMTLFGITLLALPVYAVVILGFTKKFEKLNNEQMES
                     NAVLSSSVIEDIQGIETIKALNSEDTRYRRIDSQFVDYLKKSFKYSKTESLQTALKTFI
                     QLSLNVIVLWVGAKVVMQGQLSIGQLMTFNALLAYFIDPLQSIINLQPRLQSASVAQNR
                     LNEVYQVKSEFDKKTMVNNPALLEGTISYDKVDYRYGYGADVLKDINLKISQGEKLTIV
                     GMSGSGKSTMVKLLVDFFSPSKGQVTLNGHATSEINKHTLRSYVNYVPQTPYIFSGTVK
                     ENLLLGSRPDITEEDVIKACQIAGIDQEITNLPLQFETKLDEKAKILSGGQKQRLTIAR
                     ALLFPAKVFIFDEVTSGLDTITEKKVVDNLMKLKDKTIIFIAHRLAIAERADKVIVIDH
                     GQIVEEGSHSELMSKPGFYYDLVKG"
     CDS             12619..13212
                     /locus_tag="ctg21_95"
                     /transl_table=11
                     /translation="MDAKEYESTEFYSYKFKNFSTMIIIPAAIFVLLLFIGSFFAIRQS
                     TVSSVGVVEPMVVIKKRNVNYDEGQVVTKHGQKWVAHVDQDSEVSLMPMMKAKGKVRIV
                     TYVPANKISSIKKGQKLNFSVPTADGLTSRITGKVTEIGVYPINVNKQSMYEVVSITKA
                     SDINVKYGMQGNATIVTGRSTYFNYFLDKVLNKR"
     CDS             13262..13546
                     /locus_tag="ctg21_96"
                     /transl_table=11
                     /translation="MNEAKLKEMLDKIKANSDIATDPEAQKLIETAIEKLDKKTNLQKV
                     VFNLKQDINLYSVAHGFKLPETLTKLQLLLDKDPDKWAVAGETMSLTNF"
     CDS             13815..14048
                     /locus_tag="ctg21_97"
                     /transl_table=11
                     /translation="MKVIEENEKEASRKEKWIILSISLVFGVLMNKLFLRLTSIDSFVL
                     SMLIGVGSMYVFECGYYYFRNDIQKMVRKVRG"
     CDS             14451..14732
                     /locus_tag="ctg21_98"
                     /transl_table=11
                     /translation="MPVGYISIILLLLIILVDIVVSLKLHKLVKTSDVSNILIPGIVTM
                     VIFALKDLSSFSWSSAIAIIFMSIVVLKDFYDEYQLQVKDGKNEKTSK"
     CDS             15156..15554
                     /locus_tag="ctg21_99"
                     /transl_table=11
                     /translation="MSKKEKAIGIKILSWTITSVSLIGFLGDIYSYGFSMMRFNHVIAL
                     ILVVLLLISSIIFMSAKNLLEWNQKYGFFQWIGELITLPAFFLGSLYNSTHVWYSILFL
                     SLFGGGSILFIFVKYVRRRSRNKDKTKL"
     CDS             16004..16282
                     /locus_tag="ctg21_100"
                     /transl_table=11
                     /translation="MQAFYYAMPVLAVIVVGMYIFTSIKLHKFLWLSPVVYLALIGSVG
                     LWLTIGIDIFSVSKQGVLGLLVLEAILLEGIIEEYKYQKQNLSKNEE"
ORIGIN
        1 agatgaagag taagagctaa catttcagca gatttattat gatattttcc tgtatcacca
       61 aaccgattta atgcccaagg ttgatcatga ttattccaga agagagcctg caagccgcca
      121 ccttgatcaa tcttactgtt ccaggtaagc ataatatctt ttaatttctt aaaatcaaaa
      181 ggcatcttag accatttttc accattttta tagtcaacct tgaggtgatg gaaagtgaag
      241 accattgaga gttcatgatc ttcgggacga gtataagcaa ttgaattttc aatcgtagtt
      301 gatgacattt ctccaacagt aactgattcc gggtcttgac cgaaggattt tgcatttaat
      361 tcttttagat attgttgaac tacaggtgta tcagtataaa gcgacttttc ttgaactggg
      421 tcggttgaat caactaatac attatctttt ccagtaacat taattacatc aaagcgaaaa
      481 ccatgcacac ctttaccacg ccaaaaatta actacatcaa ttaatgctgc tcgaacttca
      541 ggattatgcc aatcaaggtc tgcttgagta gggtcataaa gatgaagata ataataatct
      601 gtgtcaccaa acttagacca agctgggcca ccaaattttg attgccagtt attaggtagt
      661 tgtccatctt tgccttttct aagatagaaa aatttttgat attttttatc gccggctagg
      721 gcttttttga accattcatg ttctgttgag cagtgattta aaaccatatc gagcatcaca
      781 ttaacattaa ttgcttttaa tttagcgacc agttcttcga agtcgtccat ggttccgaat
      841 cgaggatcaa tttttttata gtcagcaatg tcatagccgt tgtcattttg tggggaaaca
      901 aaaaaaggat tgaaccaaat gaaatctaca tttagcttct tgatatagtc aattttttcg
      961 atgataccac gtaagtcgcc aataccatca ttatttgaat cgtaaaaaga ttttgggtaa
     1021 atttgataaa ttactttatt gcctaaatta ttcatcgctg ggatcctttc taaaatttaa
     1081 tcttttttct gcgagcaaaa tcaacaaact tgaatttatc aggtcgatga tatgacagag
     1141 ttagttcaaa tttagtcgta tcagctaaat aatttctgct tgcgaccagc actgcgagtt
     1201 cgttatctag ttgaagtaaa tcttgaattc tttggttaac tgtgcagaca gaaatttctt
     1261 tcgttgcata ggaaatttct aatttttctt tattttctaa ataattataa atagaagttt
     1321 ttgcagcatc ttttggaagt gaattaatag gaggtgaaag caaatagtcg caatctaaga
     1381 catcagcttg tccttctatt aatcgcaagc gttcaagatg aaaaccagca ctgttttttt
     1441 cttcaggaaa atatttgata aagccagtag gtaaatggtc ttctttttgt aaaagtaaaa
     1501 cttttgtttc agctttaagt cctaattgat tgttcaattc agcgaaactg ctaattcctg
     1561 aaataggaaa agcgtagcga tcaagattta aaactattga gccttttccg cgaatttttt
     1621 gaattaagcc taagtcagtt aagttagtaa gtgcttttcg aattgtttct cttgaagccc
     1681 catataagtc cattaattga tgttcactag ggagatattc gccaggttta tattgttgat
     1741 gcttaatttt atctactaag tcttgagcaa tagcactaac tttggattga gccataaaaa
     1801 atcctccttg tctttaatta tatacacttg tttagacaag taaagaaaaa ctttattatc
     1861 tataaaatgc ttatttaaaa gaaaaagtaa gctttttcat gaaatagtat tgacaacttg
     1921 tacagacaag tataatattt gagtcaagat gaatgaaagc ggatactttc aaagaggaga
     1981 atgaaattat ggtacaagat actactaatt tattagctcc agctactgga gcggttattg
     2041 ctttagctaa gacttctgat ccaatctttt ctcagggaac aatgggagat ggatttggat
     2101 taactccaac tgttggaaag gttgtagcac ctgtctcagg gaaaattagt atggttgccg
     2161 atactaagca tgctgtcgga atcgtcacta atgaaggact agaggtgcta gttcacatgg
     2221 gcgttgatac agttggttta aagggtgcac cattcacgat taagattgaa aatggtcaag
     2281 aagttaaagc tggcgatgaa attgctgaaa tggatttaga tgaaatcaag gctaagggat
     2341 tagatacaac aatcatggtt ttgattacta attcagctga taagatttca ggacttgatg
     2401 taactgaagg cgaggcaaaa gctggtgaag ttgtcgcaac agcttactta aaaacttcag
     2461 aaacagaaga cacttcaagt aaaaagttat cctatccaga attggctgct tttattatta
     2521 aaaatgtcgg cggtaaagat aatgttaaca atgtaattca ctgtattacc cgtttacgtt
     2581 tctatttaaa agatgaaagt aaagctaacg atgacgtttt aaaaaatcaa cgtggaattc
     2641 tagatgtgat gcatgcttct ggccaatacc aagttgtaat tggtaatgag gtaactaatg
     2701 tctttgatga agtagtcaag caattaggac ctttagatag tgaagcagct cctgctccag
     2761 aagatgacgg taaaaatcca gtttcaaaag cttttggtaa tttaattgga tttattacag
     2821 gttcaatgag tccaattatt ggtgtgattg ctgcagctgg tattattaaa ggtattttgg
     2881 cattgcttac tctgcctcaa ttaggtagtt tacttagtat caagagtaca gcctatatca
     2941 ctactagtgc aattgctgat tcagccttct tcttcttgcc agttttagtt ggttattgtg
     3001 cagcaaagag attgaattcc gatccaatca ttgcagcagt aattggtggt gtgcttgttt
     3061 accctcaatt agttgaatgg ggtaaagctt ttaagaccat gtttgaagtt ggtgggatta
     3121 agtttgagtt cttgaactat acttactcaa ttttcccaat gattttagct gcatggcttg
     3181 ctaaaaagtg tgaagattgg cttaaaaagt ggctaccatc atacttacaa atgattttta
     3241 tcccattaat tactgtttta gttgtatctg cattgacttt aatggtaact ggtccaatta
     3301 ttcaaggtgt tgctaacggg attgctgtct tcattaattg gtaagttcac gcatctggtt
     3361 ggatcggcgg attcattatt ggtggatttt accaagtatt ggttatcttt ggtttgcact
     3421 ggggtgttgt tccacttgtt gcacaacaaa ttgccggaac tggtgaaagt gcattaaacg
     3481 caattatttg ttcatcaatg attgctcaag gtgctgcagt attagctgtt gctattaagt
     3541 ctaagaaaga agacttaaaa gaattaggat ttgcttcaac tatttctgca atgtgtggtg
     3601 ttactgagcc agccgtttat ggtattagtt tgagatataa gaaagtattt atttctggtt
     3661 gtattggttc tgcatttggt ggtcttgtta ctggtttaat gcacggaaca atgtatggct
     3721 ttactggtgg attaattgga ttttcttcat tctttaatcc aaaacatcca actgacttat
     3781 caagtttcta tactttctta attgctagtg ctgtaacaat tgtagtttca tttattgtaa
     3841 cttgggtttg gggctataac gatagtatgg ttcaaggcgc caaggttgca aagaaaaaga
     3901 gacctggtag taagtaaaaa aatttatttg atttagataa acaataaaac aacgttgaaa
     3961 atttcagcgt tgttttttgc gctcaggagt tgcaaatatt aaatcatatt aatataatta
     4021 ataataattt aattaaggcg taagttaggg ggaaaggcta tgatttttga aaagcttttt
     4081 tctaaagaaa ataaaaaaga tgagatagtt gatgttaaat taaccgataa ggaatttaat
     4141 aagctcaaaa taaaattagg tgtgggggat gtaatcattg agcagggaga gaatttcagt
     4201 gttagtttta aaggaaaaaa acattacttg cctcttcttc aattatctga tggaaagttg
     4261 cagcttaagc agaagattag cttgcttgaa acaggagaag ctgagttaaa aattgtcatt
     4321 cctcaagaag tgacgctaga tagtctagat attcaaacta atagcggaaa tattgaaata
     4381 gttgatacta aagctgaaaa ggcatatctt aagtctactg agggcagagt cagagtgaga
     4441 cgagttgcaa ttgcagaatc gttacttgaa tctaccgatg gtaacgtgac tgtaagaaat
     4501 agcgatttag ctgatggaaa gcttgcaacc tatgatggag aaattaaagt ctctggctca
     4561 accttgtcac gagtagtttt gaatgttaca gatggcgata tgaatttaac tgatgtaact
     4621 attgatgaag gcagtgcaaa tttaaaagct ggtaatttta cgttagatca tgctgtcttt
     4681 aagagcgatt atgagataaa gaatatcgaa ggaaataaca ctgtgtggag agccaacttg
     4741 aaatatgcac gtgtaagaac tgcaaatggt cagaataata tttcctttga tccgcaatca
     4801 tcaggggttg tactttcaat gactacagtt gatggagata atgttgttga gtagaaaatt
     4861 aatgcaggaa gttagaaatg tattgattca gtcaaaacta ttaattttaa tacaatagtt
     4921 agccttatta gtcttttttc tataatttgt ctattttcca ggtatgattt aattcagaat
     4981 aaataaagga gacaggataa atgcaaaaat tatctagttt agaattaaag aaaatagcag
     5041 gtggaggaag aagacagatc gtcggtcagt gtgccaaaaa tattggtttt ggagctgcga
     5101 taggagcagc agctggaagc gttaaaggtg tagcgtttgg attagaaatt ggagcagttg
     5161 gtggtgctgt actaggtgca aatatgggtg cgattaaggg agccattact tgtggtggta
     5221 tggtaattgg aaggagatag gtacagatga aaaaattaaa taaaaatgag ttaggaatga
     5281 ttaagggcgg aactaactgg ggagcagttg gatcatttgc aacacaaaat ataaaatttc
     5341 ctaagcgtaa aaaaagatga aaaataatat tttcgaaaag atttatggca ctaagcttaa
     5401 tttgacttta gaagaaaaag aagaagtttt agaaaaaagt atacaattag gacgtatttt
     5461 atatattatt gaatttttat tgctgtttgg cgtgtacttt atatttttct ttgatgctaa
     5521 attagctttt tggctttttt tgagtattaa tgtagtaatt ttgtatttaa ttattccctt
     5581 tgaaattgct ttgttacgca gaaaacataa gttagtaatt acgtatcaaa ctaagggcga
     5641 taaaataaag gatatctttt tgacaactgt ttttttcgct ttaatttctg ttgccataac
     5701 tatttatttc aattggacaa agaaccatat ggtttatatt gatttgccta ctttgattgg
     5761 aataattatc ggtagccttt tgttaggttt gacatttact catccaaata aataaaacct
     5821 cgtaggattt tcctacgggg ttttataatg ccttatttaa cagtatttaa cacagaacga
     5881 atcttagttg taagcatatc aatagcaaca tcattttctc caccttctgg aacgatgatg
     5941 tctgcataac gcttagttgg ttcaataaat tggttgtaca ttggcttaac ggtctttaag
     6001 tattgatcaa taactgaatg aactgaacga ccacgttctt gtgtgtcgcg ctctaatcgt
     6061 ctaatgaaac gaatgtcatc atcagtatcg acaaagacct tgatgctcat taaattacgt
     6121 aagttttctt ctccaagaac gagaatacct tttaggataa taatatcagc tggttcagtg
     6181 tgaatagtct tttcacttct agtatgagca gtaaagtcgt aaactggcat ttcaactgcc
     6241 ttatagttca ttaattgacg aagttgttca acaagcagtg gcatgtcaaa ggcatcagga
     6301 tgatcgtagt taatcttctt gcgttctgac attgataagt catcgttatt cttgtaataa
     6361 gaatcttgcg tcataattaa aatatggtca tcttgttgta attggtcata aatttcatgg
     6421 gcaatggttg tcttcccact acctgaacca ccggcaattc caatgataat agggcgttta
     6481 ctttgcacaa ttaaaatctc cttttttaaa ctattacaat gataccttaa aattacgctc
     6541 tgtgatagat ttacaggcaa taatattgac aaatatgtgt tttttctgaa catgtgaagt
     6601 aaaataaaat tgaaagtgtt atgtatggtt ttaaaaagaa ggttttactt tgactgttca
     6661 agagaaagcc gcaatcagga attggaatcc ccgatatagg agaaatgtct atttatatct
     6721 atggatttac ggaattttag gtgcggtaac tggaattact aatgacgcag ctttatcata
     6781 ctttgatata gtagcaccag gattaatttc aggtttgaat atctttaatg cgattactgc
     6841 attattaatg tcgttgatga ttatttgggt acatgaatta ggttatcgca aaattttgct
     6901 gattttgccg cctttaactt ctatttttct ggctttgact actattacaa ctaaccaaat
     6961 agttattatg tttgcttaca ttatttcatg gactgcaatt ggagtttatg acttaatgta
     7021 tcctctaatg tggacttctt atgttcctaa agaaattaga actaagatgt ttacggtagt
     7081 aatggttgta aacttagttg ctcaaactat cttaactttc attggtggga aggcagtagt
     7141 gtactttttc agcaagatgc agggtattcc ttatgatact gcttctaatt tatctgctca
     7201 tactgctcaa ctaagtggaa gttatctagc taattatact aatgccttta gaatagtatt
     7261 gattttgact gctttagtta atgtagttgc ttttatattg gcaatattta ttaaagatga
     7321 gccaaaggac tatcgaaccg ttgggatgaa gaaaccgcaa acgccagaag agaagaagaa
     7381 agcttttgaa gccttaatta ataaaaagac gattatgtgg attctgtaca ttgcaggtat
     7441 tcaactaggt gcaagattgg ttgttcctta tattccaatt tatttgaatg attatctgca
     7501 tattccccgg ggaattactt caacgataaa tacctttcaa actgcagcaa tgtttattgg
     7561 atatttcttc gctccattct tagcaaagaa gttaggtgcc attgtttcta ttgctgctgg
     7621 gaccttaact tgtgcaccat taatgttctt aatggctaat ggtcggcatt ttggtactgg
     7681 aattactctt tttgtaattg taggagtttt gctattttta cgtagtggtt tagcaaatgc
     7741 aacaatgccg attcagcaag aagtacagat gattattgta gataaggata tgcgtccagc
     7801 ctttactgct gtggttcaga ttgcatatgc ggtaattgga ataattgatg gattatttac
     7861 agccttttac ttacttaaga cgcctgctgg gtatgcgaat gcatactaca ttgcgactgc
     7921 tctatatgta gtagtaagta tcttattaat tgtaatgttt gctaagcaat ataactggat
     7981 cttagatgag aaaaagagca catctaatga aaaatagtta attgataact taagaataat
     8041 aataaaatac cgaattagtc gtaaaagtga ctgattcggt atttttggta ttttcggggg
     8101 atgaaagatg gtaatattta agacataaaa ataatgttga ttatttaagg agaagaaatg
     8161 atgaaagata ttagaaaaga aaatattgtt aaagctacta ctttgagtga agaagaaatg
     8221 attgaagttg ttggtggaaa ggcagtgaat ggttttattg taccatcaag tatttgtaaa
     8281 ggaataaagt ggtggaaatt tggtagatag atgacagagt tatatctatt agctatttta
     8341 gtgtctattc tactagatat agttttattt tataaagtta caaaattaaa agtatcgaag
     8401 gctcattttt tattttattt attactagta attattggag ttatttgcag ttttactggt
     8461 tataaggcta ttttattcta taatgtctta gccattgtaa ttctaaatat tattcataag
     8521 gataataata atcttacact aatcagtgga acgttaatat atatttttag tgtggattta
     8581 attatagaat tattgcgagg tgtttcttta gacgtaattg agaaatttaa tatgtcaaag
     8641 aacgaaatag aatggattaa tttaggctgt attttttgtt tttttctaat tacatattta
     8701 attgtctttt tttctgcaaa ttggattaga aaaaagctaa caggtaataa ttttagaatt
     8761 ttcttttggt taatactata tttatatcta gtaactttag ttattgctgt tgtatacaaa
     8821 ggaacaaaaa acattccacc agctacaatt tttttccttt cttttttgat agtgcagttt
     8881 attttttcat tgggtctcta ctatctaatg gtgaaaaatc aaaaagtatt attaaaaaaa
     8941 tcggagcaag ataaaataat tcaagagcaa gagcagcttc aagaatatac aaaatatctt
     9001 gaagagagcg aagatgagtt acgtgctttt cgacatgatt atcgaaatat gtttaactca
     9061 ttaaaaatta gtgcacaaga aggaaatacc aaagaagtaa tccaaaagct tgatgaatat
     9121 actaaggcca atttaaatgc aaaagcattt gaaaaatata gagatgttaa tcatataaaa
     9181 ataaaatctc tcaaaagtct cattattgct aagttaacag aaatgtatag agaacatatt
     9241 ccatataatt ttgaatgtag cagtgaaatt acgaaattgc ctaaaaatat taatgaaata
     9301 gatttagtca gaatcgtcgg tataagttgt gacaatgcga ttgaagaaag caaagtatta
     9361 atagagcaaa atcaagaagc tcatattgaa attatggctt attcaagcga acgtggtgaa
     9421 tttgaatatg aaatacaaaa taaacgaagt gattctgaaa tttcaattaa acaaatacaa
     9481 caaagcggtt attcaacaaa gaaaagtcac tctggcttgg gcttagccaa tatcaatagt
     9541 attaaaaata aatatgaaaa tatgactatt tcttatgaag tgcctgaagg atactttgat
     9601 ttctatctcg tgattgaacc agaggaggaa agtgaagaat gaaatattcc gtaatcgttt
     9661 gtgatgatga cgaagtatta gcaaaaaatt tagcgaaaaa tattaaatat gcagttagta
     9721 actttaccga tgataatcca gtctacgaaa atattgaaat caatttagag ctagttgcta
     9781 ctacatttga gcaagttgta agttatgtag tcgctaatga tattcaaaat gcgatttatt
     9841 tcttagatat tgaattaagt caaaattctg aagcaaaaaa cggagtagac ttagcagaat
     9901 ttattaaaaa gcaagatcca aatgcataaa taatttttgt tactgcttat gacaaatatg
     9961 ctcctttaac ttatcgtaga agaattggtg ctattgatta tattaataag gccttagatt
    10021 caagagaaat gatgcagcga ttagaagaaa ccttgactgg cgccgttcaa agtatcaata
    10081 atcttatgaa atcaggaaga aaagaactta tctataaaat tggacggaga gttaataagg
    10141 ttgaagacac gactatttat tatcttgaaa atagtacttc acaacacaaa gttaatttga
    10201 taactgaaac tggtgtagct gaattcagaa gcaatatctc taaaattaac gaagaaaatg
    10261 attttttagt taaggtatct caatcttgtg tagtaaatcc aaataatatc aacagcatcg
    10321 acttttcaaa aaagacaata aagtttccta atggagatga agtagtgttc gctcgtagtt
    10381 gcagaaaaac tgttgaggat ctattaaata aatatccaga aattaatgtt aagtaaaagg
    10441 taagacttat gttattcaaa tataaatccg tatacgtgcc acaagtggat gagatggatt
    10501 gtggggttgc ttgtttagca atgatcttaa agcaatatca ttctcgcgta tctttagcac
    10561 atttacgtca tgaagctcgt actaatcttg aaggcacaac tgctttagga ctagtaaaga
    10621 cagcacaaaa atttaatttc aaaacagaag ccgtaaaagc agatatgtct ttatttgatg
    10681 agaatagtat tcaatatcct tttattgtcc acgtcctaaa acaaggagaa ctacttcatt
    10741 attatgtagt tcttaaaaat gctaagaatt atttagtaat tgcagatcct gatccgtcag
    10801 ttggtgtaat aaagatgcct aaagataggt ttgctcaaga atggacaggg attgcactct
    10861 ttatggttcc taatgaagac tttgaaccaa tcaaagaaaa gaagaataat ttatggtctc
    10921 tctttccata tatgtttaaa caaaagcggc tgatgattaa tatcatttta gccgctttat
    10981 taatgaccat aattagtatt tgcagttcat attttgttca aggaataatt gatacttaca
    11041 ttccagatgg aacctatcag actctttcga tcttagctgt tggactatta attgcttatg
    11101 tcttcaattc tatcttctcc tatggacaga actttttact aaatatttta ggtcaaagat
    11161 taagtattga tctaaatctg caatacatca ggcatatttt tgaattacca atggaatttt
    11221 ttgtaacgag aagaacgggt gaaattactt cacgtttttc tgatgcaagt agaattattg
    11281 acgctttggc aagtacagtt atttcgctct tcttagacct ctcaattgtg attgtgatgg
    11341 gattagtttt agcagcgcaa aatatgacat tatttgggat tacattatta gctttaccag
    11401 tatatgcagt tgtaatttta ggctttacta aaaagttcga aaaactaaat aatgaacaaa
    11461 tggagagtaa tgcggttctt agttcttctg taattgaaga tattcaagga attgaaacta
    11521 ttaaggcttt aaatagtgaa gataccagat atagaagaat tgatagtcaa tttgtagatt
    11581 acttaaagaa gtcatttaaa tatagtaaga ctgagagttt gcagacagca ctcaagacat
    11641 ttattcaatt atctcttaat gtaattgttc tttgggttgg tgcaaaagtt gtaatgcaag
    11701 gacaattgag cattggtcag ttaatgactt ttaatgcgtt gctggcatat ttcattgatc
    11761 cactgcaaag tattattaat ttacaaccgc gtctgcaatc agccagtgtt gcgcagaaca
    11821 gattaaatga agtttatcaa gtaaaaagtg aatttgataa gaaaactatg gttaataatc
    11881 cagcgttatt agaaggaaca atctcatatg ataaagttga ttatcgatat ggctatggcg
    11941 cagatgtttt aaaagatatt aatctcaaaa ttagtcaggg cgaaaaatta acgattgttg
    12001 gaatgagtgg ttctggaaaa tctacgatgg ttaagttgtt agtagatttc ttttcgccaa
    12061 gtaaaggtca ggttacatta aatggacatg caacaagtga aattaataag catacgttgc
    12121 ggtcatatgt gaattatgta cctcaaactc catatatctt ttctggaaca gttaaggaga
    12181 atttgttgtt aggatctaga ccagatatca ctgaagaaga tgtaataaag gcttgtcaga
    12241 ttgctgggat tgaccaagag ataactaatc taccactgca atttgaaaca aaattagatg
    12301 aaaaagcaaa aattctatct ggtggacaaa aacaaaggtt aacaattgct cgggcattat
    12361 tgtttcctgc aaaggtattt atttttgatg aagtaacaag tggcttagat acaattaccg
    12421 agaagaaggt agttgataat ttgatgaagc taaaggacaa gacaattatt tttatcgccc
    12481 atcgtctagc aattgcagaa cgtgcagaca aggtaattgt aattgatcat ggtcaaatag
    12541 ttgaagaagg cagccacagc gaattgatga gtaagcctgg cttttattat gacttagtga
    12601 agggataggt gagtacagat ggatgcaaaa gagtatgaaa gtacagaatt ctattcctat
    12661 aagttcaaga atttctcgac aatgattatt attccggctg ctatttttgt tctactttta
    12721 tttattggat ctttttttgc tattagacag agtacagttt cttcggttgg cgttgttgaa
    12781 ccaatggttg taattaagaa gagaaatgtt aactatgatg agggacaagt cgttacaaaa
    12841 catggtcaaa aatgggtagc tcatgttgat caagacagcg aagttagttt aatgcctatg
    12901 atgaaagcca aaggaaaagt taggattgtt acctatgtgc ctgctaataa aatctcgtct
    12961 attaagaagg ggcagaagct aaacttttct gtacctacag cagacggctt aactagtaga
    13021 ataactggca aggtaacgga gattggtgtt tatccaataa atgtgaacaa gcagagtatg
    13081 tatgaagttg tttcgattac caaagctagc gacataaatg ttaagtacgg aatgcaaggt
    13141 aatgccacaa tagtgacagg tcgtagcaca tattttaact attttttaga taaggtattg
    13201 aataaaagat aaatttgata gaataaaacg atattaaatt atattgtgtg aggataaaaa
    13261 gatgaacgaa gccaaattaa aagagatgtt agataaaatt aaggcaaact ctgacattgc
    13321 aactgatcca gaagctcaaa aattaattga aactgctatt gaaaaattgg ataagaaaac
    13381 taatttgcaa aaggtagtat ttaatctaaa gcaagatatt aatttgtatt ctgtagcaca
    13441 tggatttaaa ttgcctgaaa ctttgactaa gttgcaactt ttattagata aagatcccga
    13501 taagtgggct gttgctggtg aaacgatgtc gcttactaat ttctaaaagt taatctaata
    13561 aaaatatttt tatttataaa tttaatgcag atgtggaaga tcacaagata taataatgtt
    13621 ttaagaactg ttagcattgt gatttaattg ataagaaaaa atgttaccca acaagaaaga
    13681 caaatcagat caatattaaa gaggaaccga attagtcgta aacagggcca gtttggttct
    13741 tttttatttt tactggcttt aaaatgctaa aatttaaaca attagtagaa ggattgagtt
    13801 aaaaggtgag agagatgaaa gtaattgaag aaaatgaaaa ggaagcttca agaaaagaaa
    13861 aatggataat tttaagcata agtctagtct tcggtgtttt aatgaacaag ttgttcttac
    13921 gtttaacttc aattgatagt tttgttttat caatgctaat tggagtaggg agtatgtatg
    13981 tgtttgaatg cggatactat tacttcagaa acgatattca aaaaatggtt agaaaagtta
    14041 gaggataatt ttatcaataa cttaggagat taaggacagg attaggtctg tccgcaggtg
    14101 catttttagt aacctatgtt ggtatagcca tctgtatgat tggtagttta tggaatcagt
    14161 ggtaaaaact attgttttta gtgttggatt aatatttttt gctttaatta aatttactat
    14221 taagcaggat gaaaattcga aaaaattagt tttgcaaatg agcttagtag gatgtttttt
    14281 aattatttat aatgcaatat ggagttattt tattagatga ttttgctata aaatttgaaa
    14341 ataaatatca aatttgtcat gaataagacc agatatgtct tttttatttt tgagcacttt
    14401 ttaaatgata aaatcaaatt catagcaaga attttaggag ggaaaataga atgcctgtag
    14461 gatatatctc aattatttta cttttactaa taattttagt tgatatcgtt gtttcactaa
    14521 aattacataa gctagtaaaa acgtctgatg tttcaaatat tttaatacct ggaatagtaa
    14581 ctatggttat ttttgctttg aaagatttaa gctcattttc ctggagctca gcaatagcca
    14641 ttattttcat gagcattgtt gttttgaaag acttttatga tgaatatcaa ttacaagtaa
    14701 aagatggtaa aaatgaaaaa acgtctaaat aatagacagt taatcattat tagtactctg
    14761 gttggagcaa ttatttttac tcttgagact gtaacagacc tgttagtagg gggtacatta
    14821 actatttgta taattcttgg gaacattctc tggggtgtga tcttgggata tttaatgttc
    14881 aaacttgtga agctaagaca gatgagaaag aagaatctac atgaaattga gtaaaattag
    14941 tcaaagtaaa gatacaaata cagaagcatg gacgataatt acgctcagtg tgatctttgc
    15001 cttttgcatg aataagctat ttttatatgt aacgaatagc gacagtatca tgctaagctt
    15061 ttttgtcgga attataagta tgagtgtgtt ttcgatcacg tattattatg gcaaagatag
    15121 gattcagcaa cgtttaaaga gtaagaaaaa tatccatgag taaaaaagaa aaagctattg
    15181 gtattaaaat cttatcttgg acaattacat cagtttcttt aattggattt ctaggtgata
    15241 tttacagtta tggattttct atgatgcgtt ttaatcatgt aatagcttta atcttagttg
    15301 ttttattact aatttcttct attatattta tgtctgcaaa gaacttatta gagtggaatc
    15361 aaaagtatgg attcttccag tggatcggtg aactaattac tttaccggct tttttcctag
    15421 gcagtttata taattctaca catgtctggt attcaatatt atttttatcc ctttttggag
    15481 gaggcagtat tttatttata tttgttaaat atgttcgaag aagatcgcga aataaagata
    15541 aaacaaaatt ataataaaat actaaatcag tcaatgaata cgcagaatca gtctcttttg
    15601 aatttttaca aaaaatgata gtaaaattaa tgaataaatg ataatatttg gaaacaaaac
    15661 tactctttgg aggacaaaaa catgaaaaat gaattggaac aagtgttgaa tgactttatc
    15721 tcacttctaa gactcattat gatagaaaag gcaatgaata cttattagaa cagcttgaag
    15781 ttgccttaga caagttagaa cataatgttc aagatgaaat tgatgaagca cgtgcaactt
    15841 ataaaaatat aaatactatt tgttttgcta atcatcttca cttagaaaaa gatgaagaag
    15901 cattacttga aaagattaaa gaaatttcaa tgagtaatgg ctggcttggt ggtttaaaca
    15961 gctggaatac gaccaatact tggcctggaa agtaggtaga actatgcaag ctttttatta
    16021 tgcaatgcca gtgctagcgg taattgtagt tggaatgtac attttcactt caatcaagct
    16081 tcataaattt ctttggcttt caccagttgt atatcttgcg ttaattggaa gcgttggttt
    16141 atggttaacg attggcatag atattttttc tgtttcaaaa caaggagttc tgggattact
    16201 ggttttggaa gcaattcttt tagagggaat catcgaagaa tataaatatc aaaaacaaaa
    16261 tctatccaag aatgaagagt agtcgaaggg ctacgctttt ttagtatatt aactttatgt
    16321 gcatattttt taaaagtgaa ctaaaatgga tctgtaaaaa ggaatagaag tgataacttt
    16381 gactaaaaat gataaaaatg atgagataat taaggtcgct caattatcta ttgaagatgc
    16441 actgaaggaa ttaaatacta gtcaaagcgg cttaacaatt gatgaagttc atacattgca
    16501 gcaaaaatat ggaaagaata tttttgccaa agcaaaacaa gagccgcttt ggcaaaaatt
    16561 tttagctaat tttactaatt taatggctat tctgctttgg gtagcaggta ttattgcttt
    16621 ttgtgctgat ttagtgcaat taggaattgc tatttgggca gtaaatatca ttaacggtat
    16681 ttttagtttt tggcaagaat ttcaagctga taaggcaact gaagcgctag cgaatatgct
    16741 tccttcttat acaagagttg taagagacgg aaaagaagaa aagattttag ctaatgattt
    16801 agtacccggc gatatcgtta agcttgaaga aggagacgat atcccagctg acattcgtgt
    16861 aattgctgca acaacggctc aagctgatca atcttcgttg acaggcgaag tgaacccagt
    16921 tcataagggt gctcatgctg ttgaagacgc gaagaagaaa aatcacgctg atcttaataa
    16981 catgattttc tctggtacca atatgatgaa gggtaatgtt actggagttg ttgttaagac
    17041 agggatgaat actgattttg gtaagattgc tgaattaaca caaaatgttg ctcagcaaaa
    17101 gagtccgctt gaaaaagaac tggatacttt aactaagcag atttcaattt tagccatttc
    17161 aattgggatt attttcttct taattgctac tttctttgtt cactatcctt tagtaaaagg
    17221 ctttgtcttt gctttgggaa tgattgtagc ttttatacca gaaggattag aaccaacagt
    17281 tactttatct ttagctggtg cagttcaaag aatggcaaag aaacacgctt taattaagcg
    17341 cttatctagc gtagaaacgt taggatcgac atctgtaatt tgctcggata agacgggaac
    17401 tttaactaag aatgaaatga cggttaaaga actttggacc ttagaaaaga gctaccatgt
    17461 ttctggcgaa ggctatgcag ttcgaggtca tattaaagaa ggaccaacgc atgtttttgc
    17521 taaagataat gatactttaa aagaagtatt acttggtgga gtttttgcag acaatgcaaa
    17581 aattcaagca ccagataaga agcaccta
//
