# emapper version: emapper-2.0.1b-2-g816e190 emapper DB: 2.0 # command: ./emapper.py -i Streptococcus_salivarius/1.contigAnn/FFN/A00000125.ffn --translate --temp_dir Streptococcus_salivarius/4.eggNOG_mapper --output_dir Streptococcus_salivarius/4.eggNOG_mapper --output A00000125 --cpu 36 --keep_mapping_files -m diamond # time: Mon Jul 11 16:39:14 2022 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction taxonomic scope eggNOG OGs best eggNOG OG COG Functional cat. eggNOG free text desc. BNPNBKBE_00001 904306.HMPREF9192_0472 7.2e-223 779.6 Firmicutes Bacteria 1VQIX@1239,COG3464@1,COG3464@2 NA|NA|NA L the current gene model (or a revised gene model) may contain a frame shift BNPNBKBE_00002 435842.HMPREF0848_01038 0.0 2752.6 Bacteria Bacteria COG4932@1,COG4932@2 NA|NA|NA M domain protein BNPNBKBE_00003 1115512.EH105704_16_00040 4.1e-149 534.3 Gammaproteobacteria ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Bacteria 1MU9B@1224,1RMH0@1236,COG0840@1,COG0840@2 NA|NA|NA NT chemotaxis, protein BNPNBKBE_00004 1225184.ALXE01000005_gene107 5.8e-171 607.4 Gammaproteobacteria Bacteria 1N36S@1224,1S9CB@1236,2AQWX@1,31G5F@2 NA|NA|NA S Relaxase/Mobilisation nuclease domain BNPNBKBE_00005 45351.EDO31503 3.5e-38 164.9 Eukaryota Eukaryota 2C410@1,2SQ9Y@2759 NA|NA|NA BNPNBKBE_00006 1115512.EH105704_16_00040 5.4e-37 160.2 Gammaproteobacteria ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Bacteria 1MU9B@1224,1RMH0@1236,COG0840@1,COG0840@2 NA|NA|NA NT chemotaxis, protein BNPNBKBE_00007 500632.CLONEX_02463 2.5e-53 214.5 Clostridia Bacteria 1V1AX@1239,24EM3@186801,COG1595@1,COG1595@2 NA|NA|NA K Psort location Cytoplasmic, score BNPNBKBE_00008 1121115.AXVN01000110_gene2339 2.3e-23 114.0 Clostridia ko:K13640,ko:K21902 ko00000,ko03000 Bacteria 1UKPI@1239,25G0Q@186801,COG0789@1,COG0789@2 NA|NA|NA K Transcriptional regulator BNPNBKBE_00009 1121115.AXVN01000110_gene2338 3.3e-121 441.0 Blautia Bacteria 1TT2Z@1239,248PN@186801,3Y028@572511,COG0745@1,COG0745@2 NA|NA|NA T COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain BNPNBKBE_00010 1235802.C823_03067 3.3e-183 647.5 Eubacteriaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPBQ@1239,247M8@186801,25VDN@186806,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter BNPNBKBE_00011 1235802.C823_03068 3.5e-132 477.6 Clostridia Bacteria 1V0DC@1239,24C20@186801,28HCR@1,2Z7PI@2 NA|NA|NA BNPNBKBE_00012 1235802.C823_03069 3.3e-161 574.3 Eubacteriaceae Bacteria 1UZKD@1239,249N3@186801,25WS0@186806,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor BNPNBKBE_00013 411483.FAEPRAA2165_00908 2.1e-19 100.9 Ruminococcaceae Bacteria 1VIQ2@1239,24RMK@186801,2EFCI@1,3395F@2,3WQBA@541000 NA|NA|NA BNPNBKBE_00014 435842.HMPREF0848_00974 7.4e-144 516.5 Bacilli msmR Bacteria 1V0Z0@1239,4ISD2@91061,COG2207@1,COG2207@2 NA|NA|NA K AraC family transcriptional regulator BNPNBKBE_00015 435842.HMPREF0848_00973 0.0 1388.6 Bacilli rafA 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 Bacteria 1TQF4@1239,4HA5R@91061,COG3345@1,COG3345@2 NA|NA|NA G alpha-galactosidase BNPNBKBE_00016 864567.HMPREF8571_1568 8.2e-195 686.4 Streptococcus mitis msmE ko:K10117 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 1TQJE@1239,2TPMQ@28037,4HCBS@91061,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein BNPNBKBE_00017 888049.HMPREF8578_2007 2.7e-144 518.1 Streptococcus oralis msmF ko:K10118,ko:K15771 ko02010,map02010 M00196,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2,3.A.1.1.28 Bacteria 1TQB1@1239,1WPP8@1303,4HDV6@91061,COG1175@1,COG1175@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component BNPNBKBE_00018 1282665.H353_03773 2.2e-143 515.0 Bacilli msmG ko:K10119 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 1TR45@1239,4HCEH@91061,COG0395@1,COG0395@2 NA|NA|NA P ABC-type sugar transport system, permease component BNPNBKBE_00019 1123311.KB904476_gene1298 3e-188 664.5 Bacilli msmX ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko02000 3.A.1.1 Bacteria 1TP2M@1239,4HAMQ@91061,COG3842@1,COG3842@2 NA|NA|NA P Belongs to the ABC transporter superfamily BNPNBKBE_00020 931276.Cspa_c57840 2e-97 362.5 Clostridiaceae iolC 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TPGM@1239,247M1@186801,36F3R@31979,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase BNPNBKBE_00021 1034769.KB910518_gene3613 1.9e-195 688.7 Paenibacillaceae gtfA GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006066,GO:0006073,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0019400,GO:0019751,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0051472,GO:0071704,GO:1901615 2.4.1.329,2.4.1.7 ko:K00690,ko:K21350 ko00500,map00500 R00803 RC00028 ko00000,ko00001,ko01000 GH13 Bacteria 1TR93@1239,26TSJ@186822,4HEKC@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain BNPNBKBE_00022 1046629.Ssal_00770 9.3e-308 1062.0 Bacilli dexB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.10,3.2.1.70 ko:K01182,ko:K01215 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13 Bacteria 1TP53@1239,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G COG0366 Glycosidases BNPNBKBE_00023 1046629.Ssal_00771 3.2e-181 641.0 Bacilli galR ko:K02529 ko00000,ko03000 Bacteria 1TPZJ@1239,4HC9Z@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator BNPNBKBE_00024 435842.HMPREF0848_00971 2.1e-221 774.6 Bacilli galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TPD0@1239,4HARP@91061,COG0153@1,COG0153@2 NA|NA|NA G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) BNPNBKBE_00025 1046629.Ssal_00773 1.7e-287 994.6 Bacilli galT 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPBN@1239,4HAYJ@91061,COG4468@1,COG4468@2 NA|NA|NA G UDPglucose--hexose-1-phosphate uridylyltransferase BNPNBKBE_00026 435842.HMPREF0848_00969 1.1e-194 685.6 Bacilli galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ7N@1239,4H9U5@91061,COG1087@1,COG1087@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family BNPNBKBE_00027 1046629.Ssal_00775 7.6e-202 709.5 Bacilli galM 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 1V5UK@1239,4HTRY@91061,COG2017@1,COG2017@2 NA|NA|NA G Catalyzes the interconversion of alpha and beta anomers of maltose BNPNBKBE_00028 1046629.Ssal_00776 0.0 1221.5 Bacilli lacS GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03292,ko:K11104,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.1,2.A.2.2 Bacteria 1TRA5@1239,4HCDS@91061,COG2190@1,COG2190@2,COG2211@1,COG2211@2 NA|NA|NA G transporter BNPNBKBE_00029 1046629.Ssal_00777 0.0 2071.6 Bacilli lacL 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 Bacteria 1TPDC@1239,4HANW@91061,COG3250@1,COG3250@2 NA|NA|NA G -beta-galactosidase BNPNBKBE_00030 1046629.Ssal_00779 1.9e-209 734.9 Bacilli Bacteria 1VBH7@1239,4IS2V@91061,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat BNPNBKBE_00031 1046629.Ssal_00780 2.1e-157 561.6 Bacilli yvgN Bacteria 1TPM1@1239,4HARE@91061,COG0656@1,COG0656@2 NA|NA|NA C reductase BNPNBKBE_00032 1046629.Ssal_00781 1.9e-30 137.9 Bacilli XK27_10490 Bacteria 1VIWV@1239,2DQ9B@1,335EQ@2,4HQTB@91061 NA|NA|NA BNPNBKBE_00033 1046629.Ssal_00782 2.6e-39 167.5 Bacteria ko:K06218 ko00000,ko02048 Bacteria COG2026@1,COG2026@2 NA|NA|NA DJ nuclease activity BNPNBKBE_00034 904306.HMPREF9192_1065 1.8e-106 392.1 Firmicutes yoaK Bacteria 1V9ME@1239,COG3619@1,COG3619@2 NA|NA|NA S Protein of unknown function (DUF1275) BNPNBKBE_00035 1046629.Ssal_00784 1e-108 399.4 Bacilli drgA Bacteria 1UXYI@1239,4HBMN@91061,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase BNPNBKBE_00036 1046629.Ssal_00785 1.7e-125 455.3 Bacilli Bacteria 1TT2Z@1239,4HDGH@91061,COG0745@1,COG0745@2 NA|NA|NA T Xre family transcriptional regulator BNPNBKBE_00037 1046629.Ssal_00786 3.8e-130 471.1 Bacilli Bacteria 1UYK9@1239,4IPWV@91061,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor BNPNBKBE_00038 904306.HMPREF9192_1072 1.4e-128 465.7 Bacilli ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1VMES@1239,2EGU7@1,33AKD@2,4HQPP@91061 NA|NA|NA S ABC-2 family transporter protein BNPNBKBE_00039 1046629.Ssal_00789 2.4e-167 594.7 Bacilli bcrA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPBQ@1239,4HAGA@91061,COG1131@1,COG1131@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_00040 904306.HMPREF9192_1074 5.1e-224 783.5 Bacilli pts13C ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 Bacteria 1V5SI@1239,4HJTK@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane BNPNBKBE_00041 904306.HMPREF9192_1075 9.2e-153 546.2 Bacilli Bacteria 1V13S@1239,4HENM@91061,COG4814@1,COG4814@2 NA|NA|NA E Alpha/beta hydrolase of unknown function (DUF915) BNPNBKBE_00042 904306.HMPREF9192_1076 1.5e-74 285.4 Bacilli ywnA Bacteria 1V6FK@1239,4HKZD@91061,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator BNPNBKBE_00043 435842.HMPREF0848_00947 2.2e-149 535.0 Bacilli 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPRF@1239,4HAE7@91061,COG2514@1,COG2514@2 NA|NA|NA S glyoxalase BNPNBKBE_00044 264199.stu1363 8.7e-110 402.9 Bacilli XK27_02070 ko:K07078 ko00000 Bacteria 1V1CR@1239,4HD6W@91061,COG3560@1,COG3560@2 NA|NA|NA S nitroreductase BNPNBKBE_00045 435842.HMPREF0848_00945 2.8e-35 154.5 Firmicutes Bacteria 1VQQU@1239,2DU7U@1,33P99@2 NA|NA|NA BNPNBKBE_00046 1316408.HSISM1_1678 2.5e-27 127.5 Bacilli XK27_07105 ko:K07729 ko00000,ko03000 Bacteria 1VEZ1@1239,4HNNM@91061,COG1476@1,COG1476@2 NA|NA|NA K transcriptional BNPNBKBE_00047 1321372.AQQB01000009_gene875 4.9e-07 62.0 Streptococcus suis Bacteria 1U8Y2@1239,1WSRU@1307,29QYW@1,30BZW@2,4IIX4@91061 NA|NA|NA S Protein of unknown function (DUF3169) BNPNBKBE_00048 435842.HMPREF0848_00939 7.5e-169 599.7 Bacilli ydhF Bacteria 1TQ12@1239,4HA57@91061,COG4989@1,COG4989@2 NA|NA|NA S Aldo keto reductase BNPNBKBE_00049 889204.HMPREF9423_0305 1.1e-96 359.4 Bacilli Bacteria 1V2BY@1239,4HPW3@91061,COG1309@1,COG1309@2 NA|NA|NA K WHG domain BNPNBKBE_00050 1316408.HSISM1_1672 6e-123 446.8 Bacilli ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1U3WD@1239,4HV7M@91061,COG1136@1,COG1136@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_00051 1095727.HMPREF1117_1383 3e-204 717.6 Bacilli ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TSN2@1239,28K0P@1,2Z9QJ@2,4HU6K@91061 NA|NA|NA P FtsX-like permease family BNPNBKBE_00052 1046629.Ssal_00807 1.5e-42 178.3 Bacilli ko:K15383 ko00000,ko02000 9.A.58.2 Bacteria 1VBI9@1239,4HN2M@91061,COG4095@1,COG4095@2 NA|NA|NA S Sugar efflux transporter for intercellular exchange BNPNBKBE_00053 1046629.Ssal_00811 2.5e-50 204.5 Bacilli btuE 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 Bacteria 1V3M3@1239,4HH5Q@91061,COG0386@1,COG0386@2 NA|NA|NA O Belongs to the glutathione peroxidase family BNPNBKBE_00054 435842.HMPREF0848_00928 0.0 1674.4 Bacteria Bacteria COG5263@1,COG5263@2 NA|NA|NA S dextransucrase activity BNPNBKBE_00055 322159.STER_1318 1.8e-222 778.5 Bacilli yfnA ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,4HA66@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid BNPNBKBE_00056 435842.HMPREF0848_01140 7.5e-50 203.4 Bacilli XK27_01300 Bacteria 1V6S0@1239,4HKKR@91061,COG4405@1,COG4405@2 NA|NA|NA P Protein conserved in bacteria BNPNBKBE_00057 1046629.Ssal_00820 1.7e-27 129.8 Bacilli Bacteria 1TQ1J@1239,2Z8AD@2,4HDNN@91061,arCOG08054@1 NA|NA|NA S Carbohydrate-binding domain-containing protein Cthe_2159 BNPNBKBE_00058 435842.HMPREF0848_00923 1.1e-118 434.1 Bacilli Bacteria 1TQ1J@1239,2Z8AD@2,4HDNN@91061,arCOG08054@1 NA|NA|NA S Carbohydrate-binding domain-containing protein Cthe_2159 BNPNBKBE_00059 1046629.Ssal_00822 1.1e-16 92.0 Bacilli csbD Bacteria 1VN9B@1239,4I22P@91061,COG3237@1,COG3237@2 NA|NA|NA S CsbD-like BNPNBKBE_00060 1046629.Ssal_00823 3.4e-104 384.4 Bacilli Bacteria 1UYR2@1239,4HGVG@91061,COG2323@1,COG2323@2 NA|NA|NA S Protein of unknown function (DUF421) BNPNBKBE_00061 1046629.Ssal_00824 1.8e-59 235.3 Bacilli Bacteria 1VGVI@1239,2C9NT@1,32V8Q@2,4IRUI@91061 NA|NA|NA S Protein of unknown function (DUF3290) BNPNBKBE_00062 904306.HMPREF9192_1083 5.1e-181 640.2 Bacilli manA 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 1VRGI@1239,4HBFW@91061,COG1482@1,COG1482@2 NA|NA|NA G mannose-6-phosphate isomerase BNPNBKBE_00063 1046629.Ssal_00826 5.2e-232 810.1 Bacilli brnQ GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 ko:K03311 ko00000 2.A.26 Bacteria 1TQIS@1239,4HAKA@91061,COG1114@1,COG1114@2 NA|NA|NA E Component of the transport system for branched-chain amino acids BNPNBKBE_00064 1046629.Ssal_00827 6.5e-176 623.2 Bacilli msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K07305,ko:K12267 ko00000,ko01000 Bacteria 1TQ3E@1239,4HAIV@91061,COG0225@1,COG0225@2,COG0229@1,COG0229@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine BNPNBKBE_00066 904306.HMPREF9192_1086 6.7e-243 846.3 Bacilli norM GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 ko:K03327 ko00000,ko02000 2.A.66.1 Bacteria 1TP5U@1239,4HA4W@91061,COG0534@1,COG0534@2 NA|NA|NA V Multidrug efflux pump BNPNBKBE_00067 1046629.Ssal_00833 2.5e-223 781.2 Bacilli pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 ko:K02824,ko:K03458,ko:K16169,ko:K16170 ko00000,ko02000 2.A.40,2.A.40.1.1,2.A.40.1.2,2.A.40.3.1,2.A.40.3.2 iSB619.SA_RS02140 Bacteria 1TNZZ@1239,4HBAM@91061,COG2233@1,COG2233@2 NA|NA|NA F xanthine permease BNPNBKBE_00068 1046629.Ssal_00834 2.5e-98 364.8 Bacilli xpt GO:0003674,GO:0003824,GO:0006139,GO:0006166,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046128,GO:0046129,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816,ko:K09685 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko03000,ko04147 iYO844.BSU22070 Bacteria 1V1DU@1239,4HFNW@91061,COG0503@1,COG0503@2 NA|NA|NA F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis BNPNBKBE_00069 1046629.Ssal_00835 5.4e-124 450.3 Bacilli Bacteria 1TR32@1239,4HAUJ@91061,COG0745@1,COG0745@2 NA|NA|NA KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain BNPNBKBE_00070 264199.stu1335 7.6e-164 583.2 Bacilli Bacteria 1TQSG@1239,4HG2J@91061,COG0642@1,COG0642@2 NA|NA|NA T Histidine kinase BNPNBKBE_00071 435842.HMPREF0848_00909 4.2e-133 480.7 Bacilli macB2 ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TNZG@1239,4H9UT@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein BNPNBKBE_00072 435842.HMPREF0848_00908 0.0 1151.7 Bacilli ko:K02004,ko:K19084 ko02010,ko02020,map02010,map02020 M00258,M00731,M00737 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.134 Bacteria 1TR2D@1239,4H9SH@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter (permease) BNPNBKBE_00073 435842.HMPREF0848_00907 6.1e-93 346.7 Bacteria XK27_05000 ko:K06940 ko00000 Bacteria COG0727@1,COG0727@2 NA|NA|NA S metal cluster binding BNPNBKBE_00074 1123300.AUIN01000013_gene1665 2e-30 139.4 Bacteria liaI ko:K11619 ko02020,map02020 M00754 ko00000,ko00001,ko00002 Bacteria COG4758@1,COG4758@2 NA|NA|NA KT membrane BNPNBKBE_00075 1123300.AUIN01000013_gene1665 1.1e-15 90.5 Bacteria liaI ko:K11619 ko02020,map02020 M00754 ko00000,ko00001,ko00002 Bacteria COG4758@1,COG4758@2 NA|NA|NA KT membrane BNPNBKBE_00076 1046629.Ssal_00842 4.5e-155 553.9 Bacilli XK27_09825 ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1UZ04@1239,4HDGQ@91061,COG1131@1,COG1131@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_00077 1046629.Ssal_00843 3.1e-117 427.9 Bacilli yvfS ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1AU@1239,4HHQW@91061,COG0842@1,COG0842@2 NA|NA|NA V Transporter BNPNBKBE_00078 264199.stu1331 3.4e-82 310.8 Bacilli cdd GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009972,GO:0009987,GO:0016020,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019856,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042455,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046108,GO:0046109,GO:0046112,GO:0046131,GO:0046132,GO:0046133,GO:0046134,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0072529,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 2.4.2.4,3.5.4.5 ko:K00758,ko:K01489 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 R01570,R01878,R02484,R02485,R08221,R08222,R08230 RC00063,RC00074,RC00514 ko00000,ko00001,ko01000 Bacteria 1V58S@1239,4HHTM@91061,COG0295@1,COG0295@2 NA|NA|NA F cytidine deaminase activity BNPNBKBE_00079 1046629.Ssal_00845 9.6e-164 582.8 Bacilli yocS ko:K03453 ko00000 2.A.28 Bacteria 1TP85@1239,4HBG6@91061,COG0385@1,COG0385@2 NA|NA|NA S Transporter BNPNBKBE_00080 435842.HMPREF0848_00901 1.5e-289 1001.5 Bacilli hscC GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111 ko:K04045 ko00000,ko03110 1.A.33 iECO26_1355.ECO26_0725,iSFV_1184.SFV_0676 Bacteria 1TQ6N@1239,4HCZX@91061,COG0443@1,COG0443@2 NA|NA|NA O Belongs to the heat shock protein 70 family BNPNBKBE_00081 435842.HMPREF0848_00901 4.1e-23 113.2 Bacilli hscC GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111 ko:K04045 ko00000,ko03110 1.A.33 iECO26_1355.ECO26_0725,iSFV_1184.SFV_0676 Bacteria 1TQ6N@1239,4HCZX@91061,COG0443@1,COG0443@2 NA|NA|NA O Belongs to the heat shock protein 70 family BNPNBKBE_00082 435842.HMPREF0848_00900 1.8e-203 715.3 Bacteria anK3 ko:K07126 ko00000 Bacteria COG0666@1,COG0666@2 NA|NA|NA G response to abiotic stimulus BNPNBKBE_00084 1316408.HSISM1_1160 1.3e-208 732.3 Bacteria 2.4.1.276 ko:K14596 ko00906,map00906 R07574 RC00005,RC01992 ko00000,ko00001,ko01000,ko01003 GT1 Bacteria COG1819@1,COG1819@2 NA|NA|NA CG transferase activity, transferring hexosyl groups BNPNBKBE_00085 1316408.HSISM1_1159 3.1e-100 371.3 Bacteria Bacteria 28MX1@1,2ZB48@2 NA|NA|NA BNPNBKBE_00086 888048.HMPREF8577_0487 4.7e-197 693.7 Bacteria ugcG 2.4.1.80 ko:K00720 ko00600,ko01100,map00600,map01100 M00066 R01497 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko02000 4.D.1.4 GT21 Bacteria COG1215@1,COG1215@2 NA|NA|NA M transferase activity, transferring glycosyl groups BNPNBKBE_00087 999425.HMPREF9186_00184 1.8e-107 395.6 Bacteria 1.1.1.105 ko:K07124,ko:K15734 ko00830,map00830 R02124 RC00649 ko00000,ko00001,ko01000 Bacteria COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family BNPNBKBE_00088 435842.HMPREF0848_00898 1.5e-228 798.5 Bacilli 2.4.1.276 ko:K14596 ko00906,map00906 R07574 RC00005,RC01992 ko00000,ko00001,ko01000,ko01003 GT1 Bacteria 1V064@1239,4HUGZ@91061,COG1819@1,COG1819@2 NA|NA|NA CG Glycosyltransferase family 28 C-terminal domain BNPNBKBE_00089 435842.HMPREF0848_00897 3.2e-178 630.9 Bacilli ybjS 1.1.1.133,5.1.3.13 ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777,R06514 RC00182,RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 1TT3X@1239,4HFYX@91061,COG0451@1,COG0451@2 NA|NA|NA M NAD dependent epimerase dehydratase family protein BNPNBKBE_00090 435842.HMPREF0848_00896 6.9e-150 536.6 Bacilli gumP Bacteria 1V5YS@1239,4HIA8@91061,COG0491@1,COG0491@2 NA|NA|NA S Metallo-beta-lactamase superfamily BNPNBKBE_00091 435842.HMPREF0848_00895 1.8e-237 828.2 Bacilli 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 R02539 RC00004,RC00014 ko00000,ko00001,ko01000 Bacteria 1UYWT@1239,4HD2R@91061,COG1541@1,COG1541@2 NA|NA|NA H Coenzyme F390 synthetase BNPNBKBE_00092 435842.HMPREF0848_00894 6.2e-171 606.7 Bacilli fabH 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1UYNP@1239,4HECC@91061,COG0332@1,COG0332@2 NA|NA|NA I synthase III BNPNBKBE_00095 435842.HMPREF0848_00891 7.9e-160 569.7 Bacilli XK27_09825 ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1UZ04@1239,4HDGQ@91061,COG1131@1,COG1131@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_00096 322159.STER_1292 1.5e-132 478.8 Firmicutes yvfS ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1AU@1239,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 type transporter BNPNBKBE_00097 904306.HMPREF9192_1102 9.4e-179 632.9 Bacilli desK GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K07778 ko02020,map02020 M00479 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TSUE@1239,4HB9N@91061,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase BNPNBKBE_00098 904306.HMPREF9192_1103 2.8e-100 371.3 Bacilli desR ko:K02479,ko:K07693 ko02020,map02020 M00479 ko00000,ko00001,ko00002,ko02022 Bacteria 1TVTF@1239,4HAJW@91061,COG2197@1,COG2197@2 NA|NA|NA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain BNPNBKBE_00099 1046629.Ssal_00984 2.4e-49 201.1 Bacilli ko:K07491 ko00000 Bacteria 1TSQ0@1239,4HDZ0@91061,COG1943@1,COG1943@2 NA|NA|NA L COG1943 Transposase and inactivated derivatives BNPNBKBE_00100 888048.HMPREF8577_1925 3.2e-186 657.5 Bacilli ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TP1N@1239,4H9NR@91061,COG4586@1,COG4586@2 NA|NA|NA S abc transporter atp-binding protein BNPNBKBE_00101 1005705.HMPREF9967_1430 9e-142 509.6 Streptococcus infantis ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TSAN@1239,43FGB@68892,4HBVU@91061,COG4587@1,COG4587@2 NA|NA|NA S ABC-2 family transporter protein BNPNBKBE_00102 904306.HMPREF9192_1106 2.5e-141 508.1 Bacilli ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1US4C@1239,4IRS2@91061,COG3694@1,COG3694@2 NA|NA|NA S ABC-2 family transporter protein BNPNBKBE_00103 1419814.V470_04780 2.3e-24 120.2 Bacilli Bacteria 1VT32@1239,2BWF6@1,33SXT@2,4HUZU@91061 NA|NA|NA BNPNBKBE_00104 246201.SM12261_1633 5.4e-87 327.8 Bacilli Bacteria 1VXJP@1239,2DWFQ@1,3404D@2,4HXJV@91061 NA|NA|NA BNPNBKBE_00105 1121865.OMW_02221 1.1e-47 197.2 Enterococcaceae Bacteria 1U31N@1239,2DK2Q@1,3089C@2,4B5FA@81852,4ICRQ@91061 NA|NA|NA BNPNBKBE_00106 888048.HMPREF8577_0354 1.6e-75 288.9 Bacilli 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1V7WG@1239,4HK3X@91061,COG1714@1,COG1714@2 NA|NA|NA S RDD family BNPNBKBE_00107 1046629.Ssal_00868 1.2e-161 575.9 Bacilli yjlA Bacteria 1TP9B@1239,4H9TT@91061,COG0697@1,COG0697@2 NA|NA|NA EG membrane BNPNBKBE_00108 1046629.Ssal_00871 0.0 2265.0 Firmicutes fruA 3.2.1.1,3.2.1.26,3.2.1.65,3.2.1.80 ko:K01176,ko:K01193,ko:K01212,ko:K03332 ko00051,ko00052,ko00500,ko01100,ko04973,map00051,map00052,map00500,map01100,map04973 R00801,R00802,R00879,R02108,R02112,R02410,R03635,R03921,R05624,R06088,R11262,R11311 RC00028,RC00077,RC03278 ko00000,ko00001,ko01000 GH13,GH32 Bacteria 1TS4M@1239,COG1621@1,COG1621@2,COG3583@1,COG3583@2,COG5492@1,COG5492@2 NA|NA|NA G Belongs to the glycosyl hydrolase 32 family BNPNBKBE_00109 264199.stu1317 1.6e-144 518.8 Bacilli sdaAA 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 1TP79@1239,4HAI1@91061,COG1760@1,COG1760@2 NA|NA|NA E L-serine dehydratase BNPNBKBE_00110 435842.HMPREF0848_00882 1.5e-118 432.2 Bacilli sdaAB 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 1U8TZ@1239,4HBD6@91061,COG1760@1,COG1760@2 NA|NA|NA E L-serine dehydratase BNPNBKBE_00111 904306.HMPREF9192_1465 1e-125 456.1 Bacilli yjjG GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006206,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008655,GO:0009058,GO:0009112,GO:0009410,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019856,GO:0019859,GO:0030145,GO:0034641,GO:0034654,GO:0042221,GO:0042578,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.102,3.1.3.104,3.1.3.5,3.8.1.2 ko:K01560,ko:K07025,ko:K08723,ko:K20862 ko00230,ko00240,ko00361,ko00625,ko00740,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00740,map00760,map01100,map01110,map01120 M00125 R00183,R00511,R00548,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287,R07280 RC00017,RC00697 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_4614 Bacteria 1TWM7@1239,4HEXU@91061,COG1011@1,COG1011@2 NA|NA|NA E hydrolase BNPNBKBE_00112 904306.HMPREF9192_1466 0.0 1180.2 Bacilli uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TP4B@1239,4H9QH@91061,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision BNPNBKBE_00113 1115515.EV102420_20_00540 3.9e-287 993.4 Escherichia atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 Bacteria 1MUG7@1224,1RP4V@1236,3XP3D@561,COG0056@1,COG0056@2 NA|NA|NA F Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit BNPNBKBE_00114 1115515.EV102420_20_00530 4.4e-155 553.9 Escherichia atpG GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138 Bacteria 1MU28@1224,1RNWJ@1236,3XPI3@561,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex BNPNBKBE_00115 1115515.EV102420_20_00520 8.1e-260 902.5 Escherichia atpD GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 e_coli_core.b3732,iAF1260.b3732,iAPECO1_1312.APECO1_2729,iB21_1397.B21_03560,iBWG_1329.BWG_3423,iE2348C_1286.E2348C_4042,iEC042_1314.EC042_4119,iEC55989_1330.EC55989_4207,iECABU_c1320.ECABU_c42160,iECBD_1354.ECBD_4300,iECB_1328.ECB_03616,iECDH10B_1368.ECDH10B_3919,iECDH1ME8569_1439.ECDH1ME8569_3620,iECD_1391.ECD_03616,iECED1_1282.ECED1_4422,iECH74115_1262.ECH74115_5168,iECIAI1_1343.ECIAI1_3916,iECIAI39_1322.ECIAI39_4336,iECNA114_1301.ECNA114_3881,iECO103_1326.ECO103_4426,iECO111_1330.ECO111_4566,iECO26_1355.ECO26_4846,iECOK1_1307.ECOK1_4181,iECP_1309.ECP_3931,iECS88_1305.ECS88_4154,iECSE_1348.ECSE_4022,iECSF_1327.ECSF_3580,iECSP_1301.ECSP_4782,iECUMN_1333.ECUMN_4262,iECW_1372.ECW_m4035,iECs_1301.ECs4674,iEKO11_1354.EKO11_4613,iETEC_1333.ETEC_4023,iEcDH1_1363.EcDH1_4235,iEcE24377_1341.EcE24377A_4247,iEcSMS35_1347.EcSMS35_4100,iEcolC_1368.EcolC_4262,iG2583_1286.G2583_4528,iJO1366.b3732,iJR904.b3732,iLF82_1304.LF82_0194,iNRG857_1313.NRG857_18585,iPC815.YPO4121,iSFV_1184.SFV_3758,iSF_1195.SF3812,iSFxv_1172.SFxv_4154,iSSON_1240.SSON_3887,iS_1188.S3956,iSbBS512_1146.SbBS512_E4189,iUMN146_1321.UM146_18850,iUMNK88_1353.UMNK88_4544,iUTI89_1310.UTI89_C4285,iWFL_1372.ECW_m4035,iY75_1357.Y75_RS18410,iZ_1308.Z5230,ic_1306.c4658 Bacteria 1MUFU@1224,1RN6U@1236,3XPEM@561,COG0055@1,COG0055@2 NA|NA|NA F Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits BNPNBKBE_00116 1321372.AQQB01000060_gene15 1.4e-16 91.7 Streptococcus suis XK27_00735 Bacteria 1U94Q@1239,1WTRS@1307,29R2M@1,30C3R@2,4IJ5T@91061 NA|NA|NA BNPNBKBE_00117 1046629.Ssal_00573 3.9e-136 490.7 Bacilli glnQ 3.6.3.21 ko:K02028,ko:K10038 ko02010,map02010 M00227,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.2 Bacteria 1TNYD@1239,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E abc transporter atp-binding protein BNPNBKBE_00118 1046629.Ssal_00574 0.0 1346.3 Bacilli glnP ko:K02029,ko:K02030,ko:K10040,ko:K17073,ko:K17074 ko02010,map02010 M00228,M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1TQUG@1239,4HAJ5@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2 NA|NA|NA P ABC-type amino acid transport signal transduction systems periplasmic component domain BNPNBKBE_00119 904306.HMPREF9192_0897 1.4e-159 568.9 Bacilli ko:K07052 ko00000 Bacteria 1VA8S@1239,4IQWI@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX amino terminal protease family protein BNPNBKBE_00121 1046629.Ssal_00577 0.0 1283.5 Bacilli uvrB ko:K03702,ko:K08999 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TPKB@1239,4HB81@91061,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage BNPNBKBE_00122 904306.HMPREF9192_0901 1.8e-83 315.1 Firmicutes mutT 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1V3MM@1239,COG1051@1,COG1051@2 NA|NA|NA F Nudix family BNPNBKBE_00123 1046629.Ssal_00582 3.2e-139 501.1 Bacilli ko:K02030,ko:K17073,ko:K17074 ko02010,map02010 M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1TT16@1239,4HJ2R@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter BNPNBKBE_00124 1046629.Ssal_00583 9.4e-136 489.6 Firmicutes ko:K02030,ko:K17073,ko:K17074 ko02010,map02010 M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1TT16@1239,COG0834@1,COG0834@2 NA|NA|NA ET Belongs to the bacterial solute-binding protein 3 family BNPNBKBE_00125 1046629.Ssal_00584 4e-201 707.2 Bacilli arcT 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 Bacteria 1TQPD@1239,4HE7P@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase BNPNBKBE_00126 1046629.Ssal_00585 1e-129 469.5 Bacilli gltS ko:K02030,ko:K17073,ko:K17074 ko02010,map02010 M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1TT16@1239,4HD16@91061,COG0834@1,COG0834@2 NA|NA|NA ET Belongs to the bacterial solute-binding protein 3 family BNPNBKBE_00127 1046629.Ssal_00586 3.2e-20 103.6 Bacilli rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02970 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEHU@1239,4HNPV@91061,COG0828@1,COG0828@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS21 family BNPNBKBE_00128 873449.STRCR_1157 9.9e-51 206.1 Bacilli mscL GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 ko:K03282 ko00000,ko02000 1.A.22.1 Bacteria 1VA14@1239,4HKIA@91061,COG1970@1,COG1970@2 NA|NA|NA M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell BNPNBKBE_00129 1046629.Ssal_00588 0.0 1169.8 Bacilli dnaG ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1TQ0X@1239,4HAG2@91061,COG0358@1,COG0358@2 NA|NA|NA L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication BNPNBKBE_00130 1046629.Ssal_00589 4e-201 707.2 Bacilli sigA GO:0000988,GO:0000990,GO:0001098,GO:0001101,GO:0001108,GO:0001666,GO:0002791,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032879,GO:0032880,GO:0036293,GO:0040007,GO:0042221,GO:0043175,GO:0043254,GO:0044087,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051173,GO:0051223,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070063,GO:0070201,GO:0070482,GO:0071944,GO:0080090,GO:0090087,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:1903530,GO:2000112,GO:2000142,GO:2001141 ko:K03086,ko:K03087 ko02026,ko05111,map02026,map05111 ko00000,ko00001,ko03021 Bacteria 1TPD6@1239,4HB1H@91061,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth BNPNBKBE_00131 264199.stu1487 3.4e-55 220.7 Bacilli yitW ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1V9YV@1239,4HKC6@91061,COG2151@1,COG2151@2 NA|NA|NA K metal-sulfur cluster biosynthetic enzyme BNPNBKBE_00132 1046629.Ssal_00592 1e-170 605.9 Bacilli yfdH ko:K12999,ko:K20534 ko00000,ko01000,ko01003,ko01005,ko02000 4.D.2.1.9 GT2 Bacteria 1TPR3@1239,4HC2Z@91061,COG0463@1,COG0463@2 NA|NA|NA M COG0463, glycosyltransferases involved in cell wall biogenesis BNPNBKBE_00133 264199.stu1483 1.3e-159 568.9 Bacilli rfbD 1.1.1.133,5.1.3.13 ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777,R06514 RC00182,RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP71@1239,4HBXF@91061,COG1091@1,COG1091@2 NA|NA|NA M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose BNPNBKBE_00134 264199.stu1472 1.1e-214 752.3 Bacilli rgpA ko:K12996 ko00000,ko01000,ko01003,ko01005 GT4 Bacteria 1V7K7@1239,4HA9A@91061,COG0438@1,COG0438@2 NA|NA|NA M Domain of unknown function (DUF1972) BNPNBKBE_00135 264199.stu1471 7.5e-172 609.8 Bacilli rgpB ko:K12997 ko00000,ko01000,ko01003,ko01005 GT2 Bacteria 1V7IQ@1239,4HK7R@91061,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase, group 2 family protein BNPNBKBE_00136 435842.HMPREF0848_01097 5.2e-142 510.4 Bacilli rgpC ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1J2@1239,4HI7C@91061,COG1682@1,COG1682@2 NA|NA|NA GM Transport permease protein BNPNBKBE_00137 264199.stu1469 1.8e-223 781.6 Bacilli rgpD 3.6.3.38 ko:K01990,ko:K09689,ko:K09691 ko02010,map02010 M00249,M00250,M00254 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.101,3.A.1.103 Bacteria 1TQKK@1239,4HC6N@91061,COG1134@1,COG1134@2 NA|NA|NA P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system BNPNBKBE_00138 264199.stu1468 1.1e-179 636.0 Bacilli rgpEc ko:K12998 ko00000,ko01000,ko01003,ko01005 GT2 Bacteria 1TSUF@1239,4HF68@91061,COG0463@1,COG0463@2 NA|NA|NA M COG0463 Glycosyltransferases involved in cell wall biogenesis BNPNBKBE_00139 264199.stu1467 0.0 1184.5 Bacilli rgpF ko:K07272 ko00000,ko01000,ko01003,ko01005 Bacteria 1V95X@1239,4HIXP@91061,COG3754@1,COG3754@2 NA|NA|NA M Rhamnan synthesis protein F BNPNBKBE_00140 764291.STRUR_1429 1.6e-155 555.4 Bacilli rfbJ Bacteria 1UI8D@1239,4IST0@91061,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 BNPNBKBE_00141 1000570.HMPREF9966_0499 1.4e-43 184.1 Bacteria Bacteria COG4713@1,COG4713@2 NA|NA|NA M Psort location CytoplasmicMembrane, score BNPNBKBE_00142 1123301.KB904188_gene745 2.1e-168 599.4 Bacilli Bacteria 1V01A@1239,28HDP@1,2Z7Q8@2,4HUBR@91061 NA|NA|NA BNPNBKBE_00143 264199.stu1465 3.4e-118 431.0 Bacilli radC ko:K03630 ko00000 Bacteria 1TQ3K@1239,4HB1W@91061,COG2003@1,COG2003@2 NA|NA|NA E Belongs to the UPF0758 family BNPNBKBE_00144 1046629.Ssal_00612 1e-130 472.6 Bacilli puuD ko:K07010 ko00000,ko01002 Bacteria 1V1KC@1239,4HI59@91061,COG2071@1,COG2071@2 NA|NA|NA T peptidase C26 BNPNBKBE_00145 1046629.Ssal_00613 1.9e-118 431.8 Bacilli rex ko:K01926 ko00000,ko03000 Bacteria 1TSMR@1239,4HB7Q@91061,COG2344@1,COG2344@2 NA|NA|NA K Modulates transcription in response to changes in cellular NADH NAD( ) redox state BNPNBKBE_00146 1046629.Ssal_00614 8.2e-60 236.1 Bacilli XK27_04120 Bacteria 1VDSF@1239,2DHWG@1,32U9W@2,4HP9N@91061 NA|NA|NA S Putative amino acid metabolism BNPNBKBE_00147 1046629.Ssal_00615 1.7e-204 718.4 Bacilli iscS 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TP21@1239,4HA6H@91061,COG1104@1,COG1104@2 NA|NA|NA E Cysteine desulfurase BNPNBKBE_00148 1046629.Ssal_00616 8.7e-176 622.9 Bacilli prs 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2848 Bacteria 1TQ4I@1239,4HDRN@91061,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) BNPNBKBE_00149 904306.HMPREF9192_0936 2.4e-101 374.8 Bacilli yjbK Bacteria 1VA56@1239,4HMNE@91061,COG4116@1,COG4116@2 NA|NA|NA S Adenylate cyclase BNPNBKBE_00150 264199.stu1459 3e-119 434.5 Bacilli yjbM 2.7.6.5 ko:K07816 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 1TQ2F@1239,4HA3Q@91061,COG2357@1,COG2357@2 NA|NA|NA S Gtp pyrophosphokinase BNPNBKBE_00151 264199.stu1457 7.5e-152 543.1 Bacilli nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895 Bacteria 1TRB3@1239,4HB08@91061,COG0061@1,COG0061@2 NA|NA|NA H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP BNPNBKBE_00152 904306.HMPREF9192_0939 7e-172 609.8 Bacilli rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1TS1T@1239,4HBRY@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil BNPNBKBE_00153 1046629.Ssal_00621 3.7e-174 617.5 Bacilli pta 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028,ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 iSB619.SA_RS03155 Bacteria 1TPQ0@1239,4H9VH@91061,COG0280@1,COG0280@2 NA|NA|NA C phosphate acetyltransferase BNPNBKBE_00154 904306.HMPREF9192_0941 0.0 1219.5 Bacilli amiA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TQVS@1239,4HCCB@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substrate-binding protein, family 5 BNPNBKBE_00155 1046629.Ssal_00622 3.5e-309 1067.0 Bacilli amiA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TQVS@1239,4HCCB@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substrate-binding protein, family 5 BNPNBKBE_00156 1046629.Ssal_00624 2.1e-277 961.1 Bacilli amiC GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 ko:K02033,ko:K13894,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00349,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.21,3.A.1.5.24,3.A.1.5.25 Bacteria 1UY5U@1239,4HEZK@91061,COG0601@1,COG0601@2 NA|NA|NA P ABC transporter (Permease BNPNBKBE_00157 1046629.Ssal_00625 3.5e-166 590.9 Bacilli amiD ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP4R@1239,4HE8S@91061,COG1173@1,COG1173@2 NA|NA|NA P ABC transporter (Permease BNPNBKBE_00158 904306.HMPREF9192_0944 1.3e-201 708.8 Bacilli oppD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP6E@1239,4H9MR@91061,COG0444@1,COG0444@2 NA|NA|NA P Belongs to the ABC transporter superfamily BNPNBKBE_00159 1046629.Ssal_00627 1e-170 605.9 Bacilli oppF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1V36J@1239,4HCM4@91061,COG4608@1,COG4608@2 NA|NA|NA P Belongs to the ABC transporter superfamily BNPNBKBE_00160 1046629.Ssal_00628 2.7e-127 461.5 Firmicutes ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1VF25@1239,COG1131@1,COG1131@2 NA|NA|NA V Psort location CytoplasmicMembrane, score BNPNBKBE_00161 1046629.Ssal_00629 2.3e-117 428.3 Bacilli skfE ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPUP@1239,4HGHM@91061,COG1131@1,COG1131@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_00162 1046629.Ssal_00630 7.3e-62 243.0 Bacilli yvoA_1 ko:K07979 ko00000,ko03000 Bacteria 1VFD0@1239,4HNIT@91061,COG1725@1,COG1725@2 NA|NA|NA K Transcriptional BNPNBKBE_00163 1046629.Ssal_00631 2.2e-145 521.5 Bacilli supH Bacteria 1V2JE@1239,4IPK2@91061,COG0561@1,COG0561@2 NA|NA|NA S overlaps another CDS with the same product name BNPNBKBE_00164 1046629.Ssal_00632 4.3e-144 517.3 Bacilli XK27_02985 Bacteria 1TR2E@1239,4HGA9@91061,COG0561@1,COG0561@2 NA|NA|NA S overlaps another CDS with the same product name BNPNBKBE_00165 1046629.Ssal_00633 2.3e-193 681.8 Bacilli ftsY ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 1TPRI@1239,4HA6A@91061,COG0552@1,COG0552@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BNPNBKBE_00166 1046629.Ssal_00636 8.8e-113 412.9 Bacilli gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15680 Bacteria 1TP0M@1239,4HAYW@91061,COG0194@1,COG0194@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP BNPNBKBE_00167 1046629.Ssal_00637 3.6e-46 190.7 Bacteria rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria COG1758@1,COG1758@2 NA|NA|NA K DNA-directed 5'-3' RNA polymerase activity BNPNBKBE_00168 1046629.Ssal_00638 0.0 1530.8 Bacilli priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TNYB@1239,4H9WW@91061,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA BNPNBKBE_00169 435842.HMPREF0848_01065 1.2e-169 602.4 Bacilli fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000 iSB619.SA_RS06010 Bacteria 1TQ32@1239,4HART@91061,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus BNPNBKBE_00170 904306.HMPREF9192_0956 6.2e-241 839.7 Bacilli sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 1TP3N@1239,4HBQ6@91061,COG0144@1,COG0144@2,COG0781@1,COG0781@2 NA|NA|NA J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA BNPNBKBE_00171 1046629.Ssal_00642 2e-135 488.4 Bacilli stp 3.1.3.16 ko:K20074 ko00000,ko01000,ko01009 Bacteria 1V6K5@1239,4HCDR@91061,COG0631@1,COG0631@2 NA|NA|NA T phosphatase BNPNBKBE_00172 1046629.Ssal_00643 2e-293 1014.6 Bacilli prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 1TP3F@1239,4H9KD@91061,COG0515@1,COG0515@2,COG2815@1,COG2815@2 NA|NA|NA KLT serine threonine protein kinase BNPNBKBE_00173 1046629.Ssal_00644 2.1e-100 372.1 Bacilli kcsA GO:0003674,GO:0005215,GO:0005216,GO:0005244,GO:0005249,GO:0005261,GO:0005267,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022832,GO:0022836,GO:0022838,GO:0022839,GO:0022843,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 ko:K10716 ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 Bacteria 1V285@1239,4I17E@91061,COG1226@1,COG1226@2 NA|NA|NA P Ion transport protein BNPNBKBE_00174 435842.HMPREF0848_01061 1.9e-116 425.2 Bacilli yvqF ko:K11622 ko02020,map02020 ko00000,ko00001 Bacteria 1V3D0@1239,4HDIA@91061,COG4758@1,COG4758@2 NA|NA|NA S Membrane BNPNBKBE_00175 435842.HMPREF0848_01060 9.7e-170 602.8 Bacilli vraS 2.7.13.3 ko:K07673,ko:K07681,ko:K11617 ko02020,map02020 M00471,M00480,M00481,M00754 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TPDG@1239,4HC7E@91061,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase BNPNBKBE_00176 322159.STER_1387 3.1e-113 414.5 Bacilli vraR ko:K07694,ko:K11618 ko02020,map02020 M00480,M00481,M00754 ko00000,ko00001,ko00002,ko02022 Bacteria 1TQ1U@1239,4HA4B@91061,COG2197@1,COG2197@2 NA|NA|NA K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain BNPNBKBE_00179 1046629.Ssal_00648 9.9e-94 349.4 Bacilli rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 ko:K02860 ko00000,ko03009 Bacteria 1V6HD@1239,4HH3H@91061,COG0806@1,COG0806@2 NA|NA|NA J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes BNPNBKBE_00180 1046629.Ssal_00649 2.1e-134 485.0 Bacilli trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1TPBV@1239,4HBFV@91061,COG0336@1,COG0336@2 NA|NA|NA J Belongs to the RNA methyltransferase TrmD family BNPNBKBE_00181 1046629.Ssal_00650 5.2e-184 650.2 Bacilli trxB1 1.18.1.2,1.19.1.1 ko:K21567 ko00000,ko01000 Bacteria 1TRPN@1239,4H9V7@91061,COG0492@1,COG0492@2 NA|NA|NA C Ferredoxin--NADP reductase BNPNBKBE_00182 1046629.Ssal_00651 0.0 1423.7 Bacilli ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K03466 ko00000,ko03036 3.A.12 Bacteria 1TPJR@1239,4H9WA@91061,COG1674@1,COG1674@2 NA|NA|NA D Belongs to the FtsK SpoIIIE SftA family BNPNBKBE_00183 1046629.Ssal_00653 0.0 1436.4 Bacilli pulA 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 R02111 ko00000,ko00001,ko01000 CBM48,GH13 Bacteria 1TP3M@1239,4HBP5@91061,COG1523@1,COG1523@2 NA|NA|NA G belongs to the glycosyl hydrolase 13 family BNPNBKBE_00184 1046629.Ssal_00654 0.0 1322.8 Bacilli glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,3.2.1.141,3.2.1.20 ko:K00700,ko:K01187,ko:K01236,ko:K17734 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 M00565 R00028,R00801,R00802,R02110,R06087,R06088,R09995,R11256 RC00028,RC00049,RC00077 ko00000,ko00001,ko00002,ko01000,ko01002,ko04147 CBM48,GH13,GH31 iAPECO1_1312.APECO1_3025,iECNA114_1301.ECNA114_3542,iECOK1_1307.ECOK1_3857,iECS88_1305.ECS88_3830,iECSF_1327.ECSF_3253,iJN678.glgB,iLF82_1304.LF82_0837,iNRG857_1313.NRG857_17030,iUTI89_1310.UTI89_C3941 Bacteria 1TP4M@1239,4HAPM@91061,COG0296@1,COG0296@2 NA|NA|NA G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position BNPNBKBE_00185 904306.HMPREF9192_0971 6.4e-186 656.8 Bacilli glgC 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TNZW@1239,4HAZX@91061,COG0448@1,COG0448@2 NA|NA|NA H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans BNPNBKBE_00186 1046629.Ssal_00656 7e-177 626.7 Bacilli glgD 2.4.1.21,2.7.7.27 ko:K00703,ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948,R02421 RC00002,RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 GT5 Bacteria 1TPZ3@1239,4H9UQ@91061,COG0448@1,COG0448@2 NA|NA|NA G glucose-1-phosphate adenylyltransferase BNPNBKBE_00187 1046629.Ssal_00657 2.7e-282 977.2 Bacilli glgA GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 GT5 Bacteria 1TQ4M@1239,4HAVA@91061,COG0297@1,COG0297@2 NA|NA|NA G Synthesizes alpha-1,4-glucan chains using ADP-glucose BNPNBKBE_00188 1046629.Ssal_00658 0.0 1588.9 Bacilli glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 R02111 ko00000,ko00001,ko01000 GT35 iYO844.BSU30940 Bacteria 1TQAJ@1239,4H9XI@91061,COG0058@1,COG0058@2 NA|NA|NA G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties BNPNBKBE_00189 1046629.Ssal_00659 1.5e-100 372.1 Bacilli 2.3.1.128 ko:K03789 ko00000,ko01000,ko03009 Bacteria 1VEW7@1239,4HPE4@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase GNAT Family BNPNBKBE_00190 1046629.Ssal_00660 2.8e-282 977.2 Bacilli Bacteria 1VBKU@1239,2DI63@1,32UAI@2,4HUJH@91061 NA|NA|NA S Protein of unknown function (DUF3114) BNPNBKBE_00192 999425.HMPREF9186_00510 0.0 1479.5 Bacilli gshF 6.3.2.2,6.3.2.29,6.3.2.30,6.3.2.4 ko:K01919,ko:K01921,ko:K03802,ko:K16786,ko:K16787 ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,ko02010,map00270,map00473,map00480,map00550,map01100,map01502,map02010 M00118,M00582 R00894,R01150,R10993 RC00064,RC00090,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPGX@1239,4HAMJ@91061,COG1181@1,COG1181@2,COG2918@1,COG2918@2 NA|NA|NA H Belongs to the glutamate--cysteine ligase type 1 family BNPNBKBE_00193 904306.HMPREF9192_0998 8.8e-296 1022.3 Bacilli ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,4H9SC@91061,COG1132@1,COG1132@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_00194 1046629.Ssal_00665 0.0 1172.5 Bacilli ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_00195 1046629.Ssal_00666 5.5e-185 654.1 Bacilli XK27_10075 ko:K06158 ko00000,ko03012 Bacteria 1TU6J@1239,4HDY2@91061,COG0488@1,COG0488@2 NA|NA|NA S abc transporter atp-binding protein BNPNBKBE_00196 888808.HMPREF9380_1654 3.4e-11 76.3 Streptococcus sanguinis Bacteria 1UAAN@1239,1WS1S@1305,29RP7@1,30CSI@2,4IKNF@91061 NA|NA|NA BNPNBKBE_00198 932213.SPM24T3_13595 2.2e-26 125.2 Gammaproteobacteria umuD 3.4.21.88 ko:K01356,ko:K03503 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 1N870@1224,1SCT7@1236,COG1974@1,COG1974@2 NA|NA|NA KT Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair BNPNBKBE_00199 573.JG24_00255 5.7e-28 129.8 Gammaproteobacteria Bacteria 1NDW3@1224,1SEJS@1236,2E5MA@1,330C8@2 NA|NA|NA BNPNBKBE_00200 571.MC52_29945 9.8e-288 995.3 Gammaproteobacteria 2.7.7.49 ko:K00986 ko00000,ko01000 Bacteria 1MVI1@1224,1RQP7@1236,COG3344@1,COG3344@2 NA|NA|NA L reverse transcriptase BNPNBKBE_00201 1046629.Ssal_00101 1.3e-79 302.4 Bacilli rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02988 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1B1@1239,4HFN4@91061,COG0098@1,COG0098@2 NA|NA|NA J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body BNPNBKBE_00202 1046629.Ssal_00102 1.9e-23 114.4 Bacilli rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02907 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEG4@1239,4HNHF@91061,COG1841@1,COG1841@2 NA|NA|NA J ribosomal protein l30 BNPNBKBE_00203 1046629.Ssal_00103 5.7e-58 230.3 Bacilli rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02876 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3KE@1239,4HFPW@91061,COG0200@1,COG0200@2 NA|NA|NA J binds to the 23S rRNA BNPNBKBE_00204 1046629.Ssal_00104 2.8e-230 804.3 Bacilli secY GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0040007,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5 Bacteria 1TPHB@1239,4HAWH@91061,COG0201@1,COG0201@2 NA|NA|NA U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently BNPNBKBE_00205 904306.HMPREF9192_1977 4.7e-114 417.2 Bacilli adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS20110 Bacteria 1TP27@1239,4HA89@91061,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism BNPNBKBE_00206 1123298.KB904065_gene2021 2.7e-32 144.1 Bacilli infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009986,GO:0016020,GO:0030246,GO:0030247,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 1V9ZK@1239,4HKF4@91061,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex BNPNBKBE_00207 1123301.KB904201_gene1724 6e-15 85.5 Bacteria rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02919 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria COG0257@1,COG0257@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL36 family BNPNBKBE_00208 1046629.Ssal_00108 4.4e-56 223.8 Bacilli rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02952 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3JH@1239,4HGX6@91061,COG0099@1,COG0099@2 NA|NA|NA J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits BNPNBKBE_00209 1046629.Ssal_00109 1.9e-62 245.0 Bacilli rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02948 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3IK@1239,4HH2T@91061,COG0100@1,COG0100@2 NA|NA|NA J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome BNPNBKBE_00210 1046629.Ssal_00110 3.6e-171 607.4 Bacilli rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TPR8@1239,4H9R1@91061,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates BNPNBKBE_00211 1046629.Ssal_00111 4.4e-62 243.8 Bacilli rplQ GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02879,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6JQ@1239,4HGX2@91061,COG0203@1,COG0203@2 NA|NA|NA J ribosomal protein l17 BNPNBKBE_00212 1046629.Ssal_00112 9.9e-244 849.0 Bacilli 6.3.2.2 ko:K01919,ko:K06048 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 1TW3D@1239,4HTV4@91061,COG3572@1,COG3572@2 NA|NA|NA H gamma-glutamylcysteine synthetase BNPNBKBE_00214 1046629.Ssal_00114 1.3e-165 589.0 Bacilli fba 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ01@1239,4H9ZU@91061,COG0191@1,COG0191@2 NA|NA|NA G aldolase BNPNBKBE_00216 1046629.Ssal_00117 1.9e-95 355.1 Bacilli ywlG Bacteria 1V3H0@1239,4HH6F@91061,COG4475@1,COG4475@2 NA|NA|NA S Belongs to the UPF0340 family BNPNBKBE_00217 435842.HMPREF0848_01784 2.3e-84 318.2 Bacilli treR ko:K03486,ko:K03710 ko00000,ko03000 Bacteria 1TRF6@1239,4HDCX@91061,COG2188@1,COG2188@2 NA|NA|NA K trehalose operon BNPNBKBE_00218 1046629.Ssal_00120 1.8e-181 641.7 Bacilli treC GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005991,GO:0005993,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008788,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0015927,GO:0016052,GO:0016787,GO:0016798,GO:0033554,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046352,GO:0050896,GO:0051716,GO:0071704,GO:1901575 3.2.1.93 ko:K01226 ko00500,map00500 R00837,R06113 RC00049 ko00000,ko00001,ko01000 GH13 iECW_1372.ECW_m4600,iEKO11_1354.EKO11_4072,iEcE24377_1341.EcE24377A_4811,iEcSMS35_1347.EcSMS35_4720,iWFL_1372.ECW_m4600 Bacteria 1TP53@1239,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G COG0366 Glycosidases BNPNBKBE_00219 1046629.Ssal_00121 0.0 1270.0 Bacilli pepO 3.4.24.71 ko:K01415,ko:K07386 ko00000,ko01000,ko01002,ko04147 Bacteria 1TQTA@1239,4HDSF@91061,COG3590@1,COG3590@2 NA|NA|NA O Peptidase family M13 BNPNBKBE_00220 904306.HMPREF9192_1994 0.0 1679.5 Bacilli adhE 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 iSB619.SA_RS00885 Bacteria 1TPB4@1239,4HAN8@91061,COG1012@1,COG1012@2,COG1454@1,COG1454@2 NA|NA|NA C belongs to the iron- containing alcohol dehydrogenase family BNPNBKBE_00223 1046629.Ssal_00127 1.9e-275 954.5 Bacilli thrC 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS16355,iIT341.HP0098 Bacteria 1TPR0@1239,4H9R7@91061,COG0498@1,COG0498@2 NA|NA|NA E Threonine synthase BNPNBKBE_00224 1046629.Ssal_00128 9.6e-223 779.2 Bacilli norN ko:K03327 ko00000,ko02000 2.A.66.1 Bacteria 1TQMT@1239,4H9Y2@91061,COG0534@1,COG0534@2 NA|NA|NA V Mate efflux family protein BNPNBKBE_00225 1046629.Ssal_00129 1.4e-57 228.8 Bacilli asp Bacteria 1V3Q6@1239,4HHYJ@91061,COG1302@1,COG1302@2 NA|NA|NA S cog cog1302 BNPNBKBE_00226 1046629.Ssal_00130 4.2e-303 1046.6 Bacilli yloV ko:K07030 ko00000 Bacteria 1TQMX@1239,4HBSE@91061,COG1461@1,COG1461@2 NA|NA|NA S kinase related to dihydroxyacetone kinase BNPNBKBE_00227 1046629.Ssal_00131 0.0 1135.9 Bacilli ilvD 4.2.1.9 ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 iAF987.Gmet_1259 Bacteria 1TP1R@1239,4H9ZG@91061,COG0129@1,COG0129@2 NA|NA|NA E Belongs to the IlvD Edd family BNPNBKBE_00228 1046629.Ssal_00132 0.0 1104.4 Bacilli ilvB 2.2.1.6 ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 iYO844.BSU28310 Bacteria 1TQE8@1239,4H9VR@91061,COG0028@1,COG0028@2 NA|NA|NA EH Acetolactate synthase BNPNBKBE_00229 904306.HMPREF9192_2002 2.2e-76 291.6 Bacilli ilvN GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1V2AJ@1239,4HDY5@91061,COG0440@1,COG0440@2 NA|NA|NA E Acetolactate synthase BNPNBKBE_00230 322159.STER_1848 1.3e-193 682.2 Bacilli ilvC 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPI7@1239,4HADK@91061,COG0059@1,COG0059@2 NA|NA|NA H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate BNPNBKBE_00231 904306.HMPREF9192_2004 5.5e-239 833.2 Bacilli tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iAF1260.b1637,iBWG_1329.BWG_1452,iECDH10B_1368.ECDH10B_1771,iECDH1ME8569_1439.ECDH1ME8569_1581,iECH74115_1262.ECH74115_2349,iECIAI39_1322.ECIAI39_1418,iECNA114_1301.ECNA114_1685,iECO103_1326.ECO103_1778,iECO111_1330.ECO111_2107,iECO26_1355.ECO26_2366,iECSE_1348.ECSE_1760,iECSF_1327.ECSF_1500,iECSP_1301.ECSP_2202,iECUMN_1333.ECUMN_1928,iECW_1372.ECW_m1805,iECs_1301.ECs2346,iEKO11_1354.EKO11_2137,iETEC_1333.ETEC_1672,iEcDH1_1363.EcDH1_2003,iEcE24377_1341.EcE24377A_1847,iEcHS_1320.EcHS_A1713,iEcSMS35_1347.EcSMS35_1562,iEcolC_1368.EcolC_1992,iJO1366.b1637,iSFV_1184.SFV_1654,iSF_1195.SF1662,iSSON_1240.SSON_1519,iSbBS512_1146.SbBS512_E1829,iUMNK88_1353.UMNK88_2097,iWFL_1372.ECW_m1805,iY75_1357.Y75_RS08585 Bacteria 1TPGN@1239,4H9YV@91061,COG0162@1,COG0162@2 NA|NA|NA J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) BNPNBKBE_00232 1046629.Ssal_00136 0.0 1537.7 Bacilli pbp1B 2.4.1.129,3.4.16.4 ko:K03693,ko:K05365,ko:K05366,ko:K05367,ko:K12551,ko:K12555,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1TPM5@1239,4H9SA@91061,COG0744@1,COG0744@2 NA|NA|NA M penicillin-binding protein BNPNBKBE_00233 1046629.Ssal_00138 0.0 2300.0 Bacilli rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TP96@1239,4H9PK@91061,COG0085@1,COG0085@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates BNPNBKBE_00234 904306.HMPREF9192_2007 0.0 2381.3 Bacilli rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TNYT@1239,4HA24@91061,COG0086@1,COG0086@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates BNPNBKBE_00235 1046629.Ssal_00141 1.5e-67 261.9 Bacilli Bacteria 1VHC7@1239,4HS15@91061,COG4699@1,COG4699@2 NA|NA|NA S cog cog4699 BNPNBKBE_00236 1046629.Ssal_00142 4.2e-175 620.5 Bacilli comGA ko:K02243 M00429 ko00000,ko00002,ko02044 3.A.14.1 Bacteria 1TPGE@1239,4HB0C@91061,COG2804@1,COG2804@2 NA|NA|NA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB BNPNBKBE_00237 1046629.Ssal_00143 2.8e-143 514.6 Bacteria cglB ko:K02244 M00429 ko00000,ko00002,ko02044 3.A.14.1 Bacteria COG1459@1,COG1459@2 NA|NA|NA U protein transport across the cell outer membrane BNPNBKBE_00238 1046629.Ssal_00144 2.2e-43 181.4 Bacilli comGC GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 ko:K02245,ko:K02456 ko03070,ko05111,map03070,map05111 M00331,M00429 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1VFI9@1239,4HNNT@91061,COG4537@1,COG4537@2 NA|NA|NA U Required for transformation and DNA binding BNPNBKBE_00239 1046629.Ssal_00145 1.1e-69 269.2 Bacilli cglD ko:K02246 M00429 ko00000,ko00002,ko02044 Bacteria 1VPGT@1239,33A38@2,4HRZ0@91061,COG2165@1 NA|NA|NA NU Competence protein BNPNBKBE_00240 873449.STRCR_0577 5.3e-15 86.7 Firmicutes Bacteria 1W385@1239,2ZS6J@2,COG2165@1 NA|NA|NA NU Type II secretory pathway pseudopilin BNPNBKBE_00241 1046629.Ssal_00147 2e-71 275.0 Bacilli comGF ko:K02246,ko:K02248 M00429 ko00000,ko00002,ko02044 Bacteria 1VKRP@1239,4HR6S@91061,COG4940@1,COG4940@2 NA|NA|NA U Competence protein ComGF BNPNBKBE_00242 1198676.SMUGS5_08910 2e-12 78.6 Bacilli comGF ko:K02246,ko:K02248 M00429 ko00000,ko00002,ko02044 Bacteria 1VJKM@1239,4HQDT@91061,COG4940@1,COG4940@2 NA|NA|NA U Putative Competence protein ComGF BNPNBKBE_00243 904306.HMPREF9192_2017 5e-176 623.6 Bacilli ytxK 2.1.1.72 ko:K00571 ko00000,ko01000,ko02048 Bacteria 1TRIQ@1239,4H9SE@91061,COG0827@1,COG0827@2 NA|NA|NA L DNA methylase BNPNBKBE_00244 904306.HMPREF9192_2018 6e-219 766.5 Bacilli ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0409 Bacteria 1TQ22@1239,4HA7K@91061,COG0282@1,COG0282@2 NA|NA|NA F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction BNPNBKBE_00245 1046629.Ssal_00151 4.4e-26 123.2 Bacteria lanR ko:K07729 ko00000,ko03000 Bacteria COG1476@1,COG1476@2 NA|NA|NA K sequence-specific DNA binding BNPNBKBE_00246 1046629.Ssal_00152 8.4e-98 363.2 Bacteria ko:K07052 ko00000 Bacteria COG1266@1,COG1266@2 NA|NA|NA V CAAX protease self-immunity BNPNBKBE_00248 904306.HMPREF9192_2021 1.5e-94 352.4 Bacilli ko:K07052 ko00000 Bacteria 1VEE2@1239,4HP4A@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX amino terminal protease family protein BNPNBKBE_00249 1046629.Ssal_00155 8.2e-129 466.5 Bacilli proC 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1E@1239,4HCBY@91061,COG0345@1,COG0345@2 NA|NA|NA E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline BNPNBKBE_00250 1046629.Ssal_00156 1.4e-203 715.3 Bacilli pepA 3.4.11.7 ko:K01261,ko:K01269 ko00000,ko01000,ko01002 Bacteria 1TNZT@1239,4H9SM@91061,COG1363@1,COG1363@2 NA|NA|NA G COG1363 Cellulase M and related proteins BNPNBKBE_00251 1000570.HMPREF9966_1716 4.6e-08 63.9 Streptococcus anginosus group Bacteria 1TVXJ@1239,2BV7J@1,32QM1@2,42EDG@671232,4I4JA@91061 NA|NA|NA S Domain of unknown function (DUF4651) BNPNBKBE_00252 1046629.Ssal_00158 3.6e-54 217.2 Bacilli ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 2.7.1.180,5.3.4.1 ko:K01829,ko:K03671,ko:K03734,ko:K06196 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko02000,ko03110 5.A.1.2 Bacteria 1VAS6@1239,4HKGM@91061,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin BNPNBKBE_00253 1282665.H353_06543 2e-09 69.3 Firmicutes Bacteria 1V9AX@1239,2AYPE@1,31QTZ@2 NA|NA|NA S NTF2 fold immunity protein BNPNBKBE_00254 1046629.Ssal_00160 5.1e-113 413.7 Bacilli pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890,ko:K06878 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1V7QA@1239,4HJBD@91061,COG0073@1,COG0073@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily BNPNBKBE_00255 322159.STER_1823 4e-187 660.6 Bacilli yeeE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07112 ko00000 Bacteria 1TSNG@1239,4HDN0@91061,COG2391@1,COG2391@2 NA|NA|NA S Sulphur transport BNPNBKBE_00256 322159.STER_1822 8.3e-37 159.1 Bacteria yeeD GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 ko:K07112 ko00000 Bacteria COG0425@1,COG0425@2 NA|NA|NA O sulfur carrier activity BNPNBKBE_00257 322159.STER_1821 6.6e-66 256.5 Bacilli ssb_2 ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 1VXMZ@1239,4HXCW@91061,COG0629@1,COG0629@2 NA|NA|NA L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism BNPNBKBE_00258 1046629.Ssal_00164 2.1e-88 331.6 Bacilli tadA 3.5.4.1,3.5.4.33 ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 R00974,R01411,R02922,R10223 RC00074,RC00477,RC00514,RC00809 ko00000,ko00001,ko01000,ko03016 Bacteria 1V3HZ@1239,4HH7S@91061,COG0590@1,COG0590@2 NA|NA|NA FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) BNPNBKBE_00262 904306.HMPREF9192_2035 1.9e-155 555.1 Bacteria rrmA 2.1.1.187 ko:K00563,ko:K10947 R07233 RC00003 ko00000,ko01000,ko03000,ko03009 Bacteria COG0500@1,COG2226@2 NA|NA|NA Q methyltransferase BNPNBKBE_00263 904306.HMPREF9192_2036 1.3e-126 459.1 Bacilli ko:K07025 ko00000 Bacteria 1V73N@1239,4IU82@91061,COG0546@1,COG0546@2 NA|NA|NA S HAD hydrolase, family IA, variant BNPNBKBE_00264 1046629.Ssal_00170 5.3e-58 231.1 Bacilli dapD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 iSbBS512_1146.SbBS512_E0158,iYO844.BSU14180 Bacteria 1TQUJ@1239,4H9KY@91061,COG2171@1,COG2171@2 NA|NA|NA E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate BNPNBKBE_00265 1046629.Ssal_00172 7.4e-219 766.1 Bacilli hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823,ko:K21613 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPD7@1239,4H9SG@91061,COG1473@1,COG1473@2 NA|NA|NA E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate BNPNBKBE_00266 904306.HMPREF9192_2039 2.9e-93 347.8 Bacilli ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 Bacteria 1VA91@1239,4HM35@91061,COG0212@1,COG0212@2 NA|NA|NA H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family BNPNBKBE_00267 904306.HMPREF9192_2040 1.1e-116 426.0 Bacilli gluP 3.4.21.105 ko:K19225 ko00000,ko01000,ko01002 Bacteria 1TQXT@1239,4HCDF@91061,COG0705@1,COG0705@2 NA|NA|NA O membrane protein (homolog of Drosophila rhomboid) BNPNBKBE_00268 904306.HMPREF9192_2041 1.6e-168 598.6 Bacilli galU 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ24@1239,4HATY@91061,COG1210@1,COG1210@2 NA|NA|NA M UTP-glucose-1-phosphate uridylyltransferase BNPNBKBE_00269 1046629.Ssal_00176 2.4e-184 651.4 Bacilli gpsA GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 Bacteria 1TQ5P@1239,4HAXW@91061,COG0240@1,COG0240@2 NA|NA|NA I Glycerol-3-phosphate dehydrogenase BNPNBKBE_00270 1046629.Ssal_00177 6.7e-96 356.7 Bacteria XK27_08585 ko:K16926 M00582 ko00000,ko00002,ko02000 3.A.1.31 Bacteria 2BY0N@1,321KG@2 NA|NA|NA S Psort location CytoplasmicMembrane, score BNPNBKBE_00271 1046629.Ssal_00179 9.6e-141 506.1 Bacilli fnt ko:K06212,ko:K21993 ko00000,ko02000 1.A.16.1.1,1.A.16.1.3,1.A.16.2 Bacteria 1V164@1239,4HFJC@91061,COG2116@1,COG2116@2 NA|NA|NA P Formate nitrite transporter BNPNBKBE_00272 904306.HMPREF9192_2046 7.9e-230 802.7 Bacilli XK27_09615 Bacteria 1TPRA@1239,4HDA5@91061,COG0431@1,COG0431@2,COG2461@1,COG2461@2 NA|NA|NA C reductase BNPNBKBE_00273 1046629.Ssal_00181 8.2e-108 396.4 Bacteria XK27_09620 Bacteria COG0431@1,COG0431@2 NA|NA|NA S FMN reductase (NADPH) activity BNPNBKBE_00274 264199.stu1824 3.2e-77 294.3 Bacilli dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 ko:K01520,ko:K13038 ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100 M00053,M00120 R02100,R03269,R04231,R11896 RC00002,RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1V6HX@1239,4HIZ3@91061,COG0756@1,COG0756@2 NA|NA|NA F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA BNPNBKBE_00275 1095738.HMPREF1047_1312 1e-73 282.7 Bacteria 3.5.1.19 ko:K08281 ko00760,ko01100,map00760,map01100 R01268 RC00100 ko00000,ko00001,ko01000 Bacteria COG1335@1,COG1335@2 NA|NA|NA Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides BNPNBKBE_00276 1046629.Ssal_00184 1.5e-225 788.5 Bacilli radA ko:K04485 ko00000,ko03400 Bacteria 1TQ7Y@1239,4H9YC@91061,COG1066@1,COG1066@2 NA|NA|NA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function BNPNBKBE_00277 1046629.Ssal_00185 1.6e-126 458.8 Bacilli WQ51_05710 Bacteria 1V6BD@1239,4HIAR@91061,COG2013@1,COG2013@2 NA|NA|NA S Mitochondrial biogenesis AIM24 BNPNBKBE_00278 1046629.Ssal_00186 1e-87 329.3 Bacilli cah 4.2.1.1 ko:K01673 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 Bacteria 1V0TA@1239,4HB9V@91061,COG0288@1,COG0288@2 NA|NA|NA P Reversible hydration of carbon dioxide BNPNBKBE_00279 1046629.Ssal_00187 1.2e-50 205.7 Firmicutes Bacteria 1VNK9@1239,2DSU9@1,33HF9@2 NA|NA|NA S Protein of unknown function (DUF3397) BNPNBKBE_00280 1046629.Ssal_00188 3.7e-70 270.8 Bacilli rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1BS@1239,4HFQ0@91061,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors BNPNBKBE_00281 1046629.Ssal_00189 5.3e-119 433.7 Bacilli rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPTS@1239,4HAK4@91061,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release BNPNBKBE_00282 1046629.Ssal_00190 0.0 1292.3 Bacilli amiA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TQVS@1239,4HCCB@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substrate-binding protein, family 5 BNPNBKBE_00283 1046629.Ssal_00191 8.2e-271 939.1 Bacilli gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009986,GO:0030246,GO:0030247,GO:0044424,GO:0044464,GO:2001065 6.1.1.17,6.1.1.24 ko:K01885,ko:K09698 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 iSB619.SA_RS02860 Bacteria 1TPJC@1239,4HAKH@91061,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) BNPNBKBE_00284 1046629.Ssal_00192 4.8e-230 803.5 Bacilli 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1UYTM@1239,4IPJ9@91061,COG3290@1,COG3290@2 NA|NA|NA T signal transduction protein with a C-terminal ATPase domain BNPNBKBE_00285 1046629.Ssal_00193 3e-151 541.2 Bacteria hpk9 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria COG3290@1,COG3290@2 NA|NA|NA T protein histidine kinase activity BNPNBKBE_00286 435842.HMPREF0848_01856 2.4e-210 738.0 Bacteria hpk9 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria COG3290@1,COG3290@2 NA|NA|NA T protein histidine kinase activity BNPNBKBE_00287 1046629.Ssal_00195 2.8e-225 787.7 Bacteria fasC 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria COG3290@1,COG3290@2 NA|NA|NA T protein histidine kinase activity BNPNBKBE_00288 435842.HMPREF0848_01858 2.7e-129 468.0 Bacilli fasA ko:K07707 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko02022 Bacteria 1V392@1239,4HHAI@91061,COG3279@1,COG3279@2 NA|NA|NA KT Response regulator of the LytR AlgR family BNPNBKBE_00289 1046629.Ssal_00198 1.7e-229 801.6 Bacilli argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.argG,iSB619.SA_RS04675 Bacteria 1TP3X@1239,4HA1E@91061,COG0137@1,COG0137@2 NA|NA|NA E Belongs to the argininosuccinate synthase family. Type 1 subfamily BNPNBKBE_00290 1046629.Ssal_00199 7.8e-263 912.5 Bacilli argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TNZ6@1239,4HB24@91061,COG0165@1,COG0165@2 NA|NA|NA E Argininosuccinate lyase BNPNBKBE_00291 264199.stu1811 3.8e-54 217.2 Bacilli rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536,ko:K08998 ko00000,ko01000,ko03016 Bacteria 1VA78@1239,4HKG6@91061,COG0594@1,COG0594@2 NA|NA|NA J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme BNPNBKBE_00292 904306.HMPREF9192_2062 6.3e-146 523.5 Bacilli yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 1TQ0J@1239,4HB3J@91061,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BNPNBKBE_00293 1046629.Ssal_00202 1.1e-168 599.4 Bacilli jag ko:K06346 ko00000 Bacteria 1V3IN@1239,4HHHU@91061,COG1847@1,COG1847@2 NA|NA|NA S RNA-binding protein BNPNBKBE_00294 1046629.Ssal_00203 4.5e-98 364.0 Bacilli Bacteria 1V0VT@1239,4HPD3@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator BNPNBKBE_00295 1046629.Ssal_00204 1.7e-99 368.6 Bacilli 1.6.5.2 ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 Bacteria 1V59U@1239,4HHZC@91061,COG2249@1,COG2249@2 NA|NA|NA S NADPH-quinone reductase (modulator of drug activity B) BNPNBKBE_00296 1123299.AUKZ01000036_gene1534 3.4e-14 83.2 Bacteria rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02914 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria COG0230@1,COG0230@2 NA|NA|NA J Ribosomal protein L34 BNPNBKBE_00297 1046629.Ssal_00206 9.1e-225 785.8 Bacilli tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 R03789,R10209 RC00063 ko00000,ko01000,ko03016 Bacteria 1TNZ4@1239,4HCNM@91061,COG0343@1,COG0343@2 NA|NA|NA F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) BNPNBKBE_00298 1123315.AUIP01000021_gene2248 9.5e-31 139.0 Bacilli XK27_00530 Bacteria 1VPFZ@1239,4HFGV@91061,COG3942@1,COG3942@2 NA|NA|NA M CHAP domain protein BNPNBKBE_00299 435842.HMPREF0848_00171 6.8e-107 393.3 Bacilli abiGI Bacteria 1V3JU@1239,4HMVW@91061,COG5340@1,COG5340@2 NA|NA|NA K Transcriptional regulator, AbiEi antitoxin BNPNBKBE_00300 1046629.Ssal_01630 2.5e-273 947.6 Bacilli opuD GO:0003674,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006970,GO:0008150,GO:0008324,GO:0008519,GO:0009266,GO:0009409,GO:0009628,GO:0015075,GO:0015101,GO:0015199,GO:0015651,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0022857,GO:0031460,GO:0034220,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0072337,GO:0072349,GO:0072488,GO:0098655 ko:K05020 ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 Bacteria 1TRS6@1239,4HA7U@91061,COG1292@1,COG1292@2 NA|NA|NA M Belongs to the BCCT transporter (TC 2.A.15) family BNPNBKBE_00301 1046629.Ssal_01629 1.8e-28 131.3 Bacteria ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria COG0583@1,COG0583@2 NA|NA|NA K DNA-binding transcription factor activity BNPNBKBE_00302 1046629.Ssal_00725 7.5e-159 568.2 Bacteria Bacteria COG5263@1,COG5263@2 NA|NA|NA S dextransucrase activity BNPNBKBE_00303 1046629.Ssal_00094 3.9e-60 237.3 Bacilli rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02874 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3N0@1239,4HGYR@91061,COG0093@1,COG0093@2 NA|NA|NA J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome BNPNBKBE_00304 1046629.Ssal_00095 1.4e-47 195.3 Bacilli rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02895 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9ZQ@1239,4HKH9@91061,COG0198@1,COG0198@2 NA|NA|NA J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit BNPNBKBE_00305 1046629.Ssal_00096 1.6e-94 352.1 Bacilli rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02931 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPE0@1239,4HBAX@91061,COG0094@1,COG0094@2 NA|NA|NA J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits BNPNBKBE_00306 1000570.HMPREF9966_1576 1.5e-28 131.3 Streptococcus anginosus group rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEF6@1239,42EG0@671232,4HNKX@91061,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site BNPNBKBE_00307 1046629.Ssal_00098 1.2e-67 262.3 Bacilli rpsH GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904 ko:K02994 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3KK@1239,4HH32@91061,COG0096@1,COG0096@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit BNPNBKBE_00308 1046629.Ssal_00099 6.6e-93 346.7 Bacilli rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02933 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1FC@1239,4HFQD@91061,COG0097@1,COG0097@2 NA|NA|NA J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center BNPNBKBE_00309 491915.Aflv_2471 3.7e-14 84.3 Bacilli Bacteria 1VGVZ@1239,2AU0W@1,31JKY@2,4IRJR@91061 NA|NA|NA BNPNBKBE_00311 592026.GCWU0000282_002596 4.6e-10 71.6 Bacteria ywaD Bacteria COG2234@1,COG2234@2 NA|NA|NA DZ aminopeptidase activity BNPNBKBE_00312 877411.JMMA01000002_gene1369 2e-12 80.5 Ruminococcaceae Bacteria 1UR4B@1239,24JEJ@186801,2DB72@1,2Z7JI@2,3WJ6U@541000 NA|NA|NA S Putative amidase domain BNPNBKBE_00313 1378168.N510_02614 6.4e-16 90.1 Firmicutes Bacteria 1UHWD@1239,COG1476@1,COG1476@2 NA|NA|NA K helix-turn-helix BNPNBKBE_00314 1046629.Ssal_01225 5e-111 407.1 Bacilli tcyB_2 ko:K02029,ko:K02030,ko:K10040,ko:K17073,ko:K17074 ko02010,map02010 M00228,M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1V14N@1239,4HJ9W@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter (permease) BNPNBKBE_00315 1046629.Ssal_01222 6.7e-139 500.0 Bacilli glnQ 3.6.3.21 ko:K02028,ko:K10041 ko02010,map02010 M00228,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E abc transporter atp-binding protein BNPNBKBE_00316 435842.HMPREF0848_00558 1.1e-142 512.7 Bacilli peb1A GO:0005575,GO:0005623,GO:0009986,GO:0044464 ko:K10039 ko02010,map02010 M00228 ko00000,ko00001,ko00002,ko02000 3.A.1.3 Bacteria 1TT11@1239,4HAHV@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC-type amino acid transport signal transduction systems, periplasmic component domain BNPNBKBE_00317 888833.HMPREF9421_1151 1.8e-279 968.0 Bacilli opuD GO:0003674,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006970,GO:0008150,GO:0008324,GO:0008519,GO:0009266,GO:0009409,GO:0009628,GO:0015075,GO:0015101,GO:0015199,GO:0015651,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0022857,GO:0031460,GO:0034220,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0072337,GO:0072349,GO:0072488,GO:0098655 ko:K05020 ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 Bacteria 1TRS6@1239,4HA7U@91061,COG1292@1,COG1292@2 NA|NA|NA M Belongs to the BCCT transporter (TC 2.A.15) family BNPNBKBE_00318 1095726.HMPREF1116_0263 3.4e-36 157.5 Bacteria ko:K10716 ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 Bacteria COG1226@1,COG1226@2 NA|NA|NA P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) BNPNBKBE_00319 1046629.Ssal_00672 9.9e-83 312.8 Bacilli Bacteria 1UXB4@1239,4HCTD@91061,COG4932@1,COG4932@2 NA|NA|NA M Pilin isopeptide linkage domain protein BNPNBKBE_00320 904306.HMPREF9192_0370 2.5e-129 468.8 Bacilli vanY 3.4.17.14,3.5.1.28 ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 M00651,M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 Bacteria 1V1F7@1239,4ISN5@91061,COG0739@1,COG0739@2,COG0860@1,COG0860@2,COG1705@1,COG1705@2,COG1876@1,COG1876@2,COG3757@1,COG3757@2 NA|NA|NA M D-alanyl-D-alanine carboxypeptidase BNPNBKBE_00321 904306.HMPREF9192_0374 2.2e-137 495.0 Bacilli cnhA 3.5.1.3 ko:K11206,ko:K13566 ko00250,map00250 R00269,R00348 RC00010 ko00000,ko00001,ko01000 Bacteria 1TQDK@1239,4HC44@91061,COG0388@1,COG0388@2 NA|NA|NA S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase BNPNBKBE_00322 1046629.Ssal_01700 2.8e-221 774.2 Bacilli mtnE 2.6.1.83 ko:K08969,ko:K10206 ko00270,ko00300,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map01100,map01110,map01130,map01230 M00034,M00527 R07396,R07613 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TQD6@1239,4HAHQ@91061,COG0436@1,COG0436@2 NA|NA|NA E mutations do not affect methionine salvage in vivo however BNPNBKBE_00323 1046629.Ssal_01699 8e-180 636.3 Bacilli argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1782,iSSON_1240.SSON_4131,iYO844.BSU11190 Bacteria 1TPVI@1239,4H9YD@91061,COG0002@1,COG0002@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde BNPNBKBE_00324 435842.HMPREF0848_00097 9.5e-217 759.2 Bacilli argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 ko:K00620,ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1783 Bacteria 1TPBP@1239,4H9TQ@91061,COG1364@1,COG1364@2 NA|NA|NA E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate BNPNBKBE_00325 1046629.Ssal_01697 3.8e-123 447.6 Firmicutes argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP0N@1239,COG0548@1,COG0548@2 NA|NA|NA E Belongs to the acetylglutamate kinase family. ArgB subfamily BNPNBKBE_00326 1046629.Ssal_01696 2e-203 714.9 Bacilli argD GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP9S@1239,4H9VZ@91061,COG4992@1,COG4992@2 NA|NA|NA E acetylornithine aminotransferase BNPNBKBE_00327 1046629.Ssal_01695 7.2e-129 466.8 Bacilli yxkH Bacteria 1V6AW@1239,4HHC9@91061,COG0726@1,COG0726@2 NA|NA|NA G deacetylase BNPNBKBE_00328 1046629.Ssal_01694 2.6e-236 824.3 Bacilli hom GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1294,iSB619.SA_RS06610 Bacteria 1TQ2H@1239,4HBAP@91061,COG0460@1,COG0460@2 NA|NA|NA E homoserine dehydrogenase BNPNBKBE_00329 1046629.Ssal_01693 5.9e-152 543.5 Bacilli thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545 Bacteria 1TRWS@1239,4HCQN@91061,COG0083@1,COG0083@2 NA|NA|NA E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate BNPNBKBE_00330 322159.STER_0508 5.3e-148 530.4 Bacilli rarD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 ko:K05786 ko00000,ko02000 2.A.7.7 Bacteria 1TQF2@1239,4HAYU@91061,COG2962@1,COG2962@2 NA|NA|NA S Transporter BNPNBKBE_00331 1123315.AUIP01000020_gene2219 4e-17 95.1 Bacteria Bacteria COG3212@1,COG3212@2 NA|NA|NA T peptidase BNPNBKBE_00332 1123314.AUIO01000005_gene141 1.4e-14 85.1 Bacilli coiA 3.6.4.12 ko:K03657,ko:K06198 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TRGD@1239,4HFP5@91061,COG4469@1,COG4469@2 NA|NA|NA S Competence protein BNPNBKBE_00335 1046629.Ssal_00547 4e-104 384.0 Bacilli Bacteria 1VENC@1239,4HQ31@91061,COG1853@1,COG1853@2 NA|NA|NA S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family BNPNBKBE_00336 1035189.HMPREF9954_2024 3e-96 357.8 Streptococcus infantis 2.3.1.128,5.2.1.8 ko:K03768,ko:K03790 ko00000,ko01000,ko03009,ko03110 Bacteria 1V2C6@1239,43F7Y@68892,4HG3C@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain BNPNBKBE_00337 888833.HMPREF9421_1932 1.5e-95 355.5 Bacilli Bacteria 1UHQN@1239,4IS6C@91061,COG4088@1,COG4088@2 NA|NA|NA F AAA domain BNPNBKBE_00338 1046629.Ssal_00550 0.0 1746.1 Bacilli valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iLJ478.TM1817 Bacteria 1TPN4@1239,4HB85@91061,COG0525@1,COG0525@2 NA|NA|NA J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner BNPNBKBE_00339 1123298.KB904069_gene1213 2.4e-16 90.9 Bacteria atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2ZI0B@2,COG0636@1 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation BNPNBKBE_00340 1046629.Ssal_01685 9e-122 443.0 Bacilli atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666 Bacteria 1TQIT@1239,4H9NV@91061,COG0356@1,COG0356@2 NA|NA|NA C it plays a direct role in the translocation of protons across the membrane BNPNBKBE_00341 1046629.Ssal_01684 1.6e-77 295.4 Bacilli atpF ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iHN637.CLJU_RS01170,iYO844.BSU36850 Bacteria 1VB85@1239,4HM64@91061,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) BNPNBKBE_00342 1046629.Ssal_01683 1e-85 322.8 Bacilli atpH GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iSF_1195.SF3815,iSFxv_1172.SFxv_4157,iS_1188.S3953 Bacteria 1VAG3@1239,4HKW1@91061,COG0712@1,COG0712@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation BNPNBKBE_00343 904306.HMPREF9192_0397 2.9e-279 967.2 Bacilli atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 Bacteria 1TNZ8@1239,4HAMZ@91061,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit BNPNBKBE_00344 435842.HMPREF0848_00118 6.2e-157 560.1 Bacilli atpG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611,iSB619.SA_RS10970,iYO844.BSU36820 Bacteria 1TPBX@1239,4HB0E@91061,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex BNPNBKBE_00345 1046629.Ssal_01680 7.9e-263 912.5 Bacilli atpD 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iSB619.SA_RS10965 Bacteria 1TPGF@1239,4HAT6@91061,COG0055@1,COG0055@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits BNPNBKBE_00346 1046629.Ssal_01679 2.6e-68 264.6 Bacilli atpC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190 Bacteria 1VA89@1239,4HKHS@91061,COG0355@1,COG0355@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane BNPNBKBE_00347 435842.HMPREF0848_00121 3.5e-217 760.8 Bacilli ftsW ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 2.A.103.1 Bacteria 1TPT7@1239,4HAEV@91061,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family BNPNBKBE_00348 1046629.Ssal_01677 2.8e-224 784.3 Bacilli tuf GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 ko:K02358,ko:K15771 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 Bacteria 1TPKC@1239,4HAEH@91061,COG0050@1,COG0050@2 NA|NA|NA J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis BNPNBKBE_00349 1046629.Ssal_01675 9.9e-135 486.1 Bacilli tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS19265 Bacteria 1TP2F@1239,4HAPT@91061,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) BNPNBKBE_00350 435842.HMPREF0848_00124 0.0 1279.2 Bacilli tkt 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPIB@1239,4HADA@91061,COG0021@1,COG0021@2 NA|NA|NA G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate BNPNBKBE_00352 904306.HMPREF9192_0405 1e-108 399.4 Bacilli tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS02535 Bacteria 1V1HE@1239,4HGWR@91061,COG0125@1,COG0125@2 NA|NA|NA F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis BNPNBKBE_00353 904306.HMPREF9192_0406 2.7e-160 571.2 Bacilli holB 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TRVS@1239,4HA3T@91061,COG0470@1,COG0470@2 NA|NA|NA L dna polymerase iii BNPNBKBE_00354 1046629.Ssal_01671 4.4e-133 480.7 Bacilli yaaT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 Bacteria 1TP1V@1239,4H9M9@91061,COG1774@1,COG1774@2 NA|NA|NA S stage 0 sporulation protein BNPNBKBE_00355 1046629.Ssal_01670 1.2e-54 218.8 Bacilli yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 Bacteria 1VA1F@1239,4HKND@91061,COG4467@1,COG4467@2 NA|NA|NA L Involved in initiation control of chromosome replication BNPNBKBE_00356 1046629.Ssal_01669 3.3e-158 564.3 Bacilli rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 1TP6U@1239,4HAH8@91061,COG0313@1,COG0313@2 NA|NA|NA H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA BNPNBKBE_00357 365659.smi_0683 1.8e-148 531.9 Bacilli amt ko:K03320 ko00000,ko02000 1.A.11 Bacteria 1TQYG@1239,4HBGK@91061,COG0004@1,COG0004@2 NA|NA|NA P Ammonium Transporter BNPNBKBE_00358 1046629.Ssal_01666 2.3e-103 381.7 Bacteria mur1 3.4.17.14,3.5.1.28 ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 M00651,M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 Bacteria COG1705@1,COG1705@2 NA|NA|NA NU amidase activity BNPNBKBE_00359 904306.HMPREF9192_0413 2.6e-141 508.1 Bacilli XK27_04800 Bacteria 1V1KS@1239,4IPK6@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase BNPNBKBE_00360 435842.HMPREF0848_00134 2e-75 288.5 Firmicutes Bacteria 1VMYY@1239,2E80M@1,33I28@2 NA|NA|NA S Bacterial inner membrane protein BNPNBKBE_00361 1046629.Ssal_01662 5.2e-113 414.5 Bacteria 3.4.17.14,3.5.1.28 ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 M00651,M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 Bacteria COG1705@1,COG1705@2 NA|NA|NA NU amidase activity BNPNBKBE_00362 1046629.Ssal_01661 3.5e-294 1016.9 Bacilli nptA ko:K03324 ko00000,ko02000 2.A.58.2 Bacteria 1TP4K@1239,4HAZ0@91061,COG1283@1,COG1283@2 NA|NA|NA P COG1283 Na phosphate symporter BNPNBKBE_00363 1046629.Ssal_01660 4.9e-218 763.5 Bacilli nagA 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 R02059 RC00166,RC00300 ko00000,ko00001,ko01000 Bacteria 1TPFK@1239,4HC6C@91061,COG1820@1,COG1820@2 NA|NA|NA G Belongs to the metallo-dependent hydrolases superfamily. NagA family BNPNBKBE_00364 1046629.Ssal_01659 7.8e-222 776.2 Bacilli Bacteria 1U601@1239,4HBYW@91061,COG3949@1,COG3949@2 NA|NA|NA S membrane BNPNBKBE_00365 1203590.HMPREF1481_00615 2.5e-67 261.2 Bacteria Bacteria COG3791@1,COG3791@2 NA|NA|NA S Glutathione-dependent formaldehyde-activating BNPNBKBE_00366 1046629.Ssal_01658 3.7e-176 624.0 Bacilli glyQ GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016875,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 ko:K01878,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF1260.b3560,iAF987.Gmet_2942,iJO1366.b3560,iPC815.YPO4072,iY75_1357.Y75_RS19360 Bacteria 1TPW8@1239,4HBCF@91061,COG0752@1,COG0752@2 NA|NA|NA J glycyl-tRNA synthetase alpha subunit BNPNBKBE_00367 1046629.Ssal_01657 0.0 1271.9 Bacilli glyS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01879,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iJN678.glyS,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,ic_1306.c4378 Bacteria 1TNZ7@1239,4H9NT@91061,COG0751@1,COG0751@2 NA|NA|NA J Glycyl-tRNA synthetase beta subunit BNPNBKBE_00368 1046629.Ssal_01656 1.3e-38 165.2 Bacilli ynzC Bacteria 1VEKJ@1239,4HNIB@91061,COG4224@1,COG4224@2 NA|NA|NA S UPF0291 protein BNPNBKBE_00369 904306.HMPREF9192_0421 1.1e-251 875.5 Bacilli cycA GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601 Bacteria 1TP97@1239,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E permease BNPNBKBE_00370 1215915.BN193_08720 6.4e-10 71.2 Lactococcus uvrX 2.7.7.7 ko:K02346,ko:K03502,ko:K14161 ko00000,ko01000,ko03400 Bacteria 1TP42@1239,1YBFV@1357,4HA1P@91061,COG0389@1,COG0389@2 NA|NA|NA L impB/mucB/samB family BNPNBKBE_00371 1046629.Ssal_01653 0.0 1182.2 Bacilli pts33BCA 2.7.1.201,2.7.1.208,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810,ko:K02817,ko:K02818,ko:K02819,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00269,M00270,M00271,M00272,M00303,M00806 R00811,R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.13,4.A.1.2.2,4.A.1.2.4,4.A.1.2.5,4.A.1.2.6,4.A.1.2.8,4.A.1.2.9 Bacteria 1TP5X@1239,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G pts system BNPNBKBE_00372 1046629.Ssal_01652 1.5e-138 498.8 Bacteria ppiA 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria COG0652@1,COG0652@2 NA|NA|NA O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides BNPNBKBE_00376 1046629.Ssal_01649 5.8e-69 266.9 Firmicutes Bacteria 1VPVM@1239,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix BNPNBKBE_00377 888048.HMPREF8577_0730 1.6e-41 175.3 Bacilli Bacteria 1W48Q@1239,290G9@1,2ZN5B@2,4I1UG@91061 NA|NA|NA BNPNBKBE_00379 1046629.Ssal_01647 1.2e-166 592.4 Bacilli fhuR Bacteria 1V53I@1239,4HIEU@91061,COG0583@1,COG0583@2 NA|NA|NA K transcriptional regulator (lysR family) BNPNBKBE_00380 1046629.Ssal_01646 2.8e-76 291.2 Bacilli lspA 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1VA9R@1239,4HIR4@91061,COG0597@1,COG0597@2 NA|NA|NA MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins BNPNBKBE_00381 435842.HMPREF0848_00153 1.1e-161 575.9 Bacilli rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1TPCM@1239,4HBG2@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil BNPNBKBE_00382 1046629.Ssal_01644 1.8e-87 328.6 Bacilli pyrR 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000,ko03000 Bacteria 1V3GV@1239,4HGYE@91061,COG2065@1,COG2065@2 NA|NA|NA F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant BNPNBKBE_00383 1046629.Ssal_01642 1.8e-221 775.0 Bacilli pyrP ko:K02824,ko:K16169 ko00000,ko02000 2.A.40.1.1,2.A.40.1.2,2.A.40.3.1 iLJ478.TM0819 Bacteria 1TQKX@1239,4HAEU@91061,COG2233@1,COG2233@2 NA|NA|NA F uracil Permease BNPNBKBE_00384 1046629.Ssal_01641 3.8e-173 614.0 Bacilli pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00608,ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15490 Bacteria 1TQ96@1239,4H9M6@91061,COG0540@1,COG0540@2 NA|NA|NA F Belongs to the ATCase OTCase family BNPNBKBE_00385 1046629.Ssal_01640 4.6e-210 736.9 Bacilli carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383,iYO844.BSU15510 Bacteria 1TQ8N@1239,4H9Z0@91061,COG0505@1,COG0505@2 NA|NA|NA F carbamoyl-phosphate synthetase glutamine chain BNPNBKBE_00386 904306.HMPREF9192_0437 0.0 2058.9 Bacilli carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPID@1239,4HAEY@91061,COG0458@1,COG0458@2 NA|NA|NA F carbamoyl-phosphate synthetase ammonia chain BNPNBKBE_00387 1046629.Ssal_01638 1.6e-124 452.2 Bacilli 2.1.1.223 ko:K15460 ko00000,ko01000,ko03016 Bacteria 1UJ4P@1239,4IT17@91061,COG4123@1,COG4123@2 NA|NA|NA S Putative SAM-dependent methyltransferase BNPNBKBE_00388 435842.HMPREF0848_00161 9.8e-180 636.3 Bacilli acrA GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K02005 ko00000 Bacteria 1VBR9@1239,4HG5X@91061,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family BNPNBKBE_00389 904306.HMPREF9192_0440 1.3e-120 439.1 Bacilli macB ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPBJ@1239,4HBMF@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein BNPNBKBE_00390 435842.HMPREF0848_00163 6.5e-213 746.5 Bacilli ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPUU@1239,4HF9U@91061,COG0577@1,COG0577@2 NA|NA|NA V permease protein BNPNBKBE_00391 435842.HMPREF0848_00164 5.6e-78 297.0 Bacilli rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3JJ@1239,4HH0N@91061,COG0244@1,COG0244@2 NA|NA|NA J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors BNPNBKBE_00392 264199.stu0537 2.1e-45 188.3 Bacilli rplL ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6EI@1239,4HIGQ@91061,COG0222@1,COG0222@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation BNPNBKBE_00395 1046629.Ssal_00736 1.1e-20 104.8 Bacteria Bacteria COG5263@1,COG5263@2 NA|NA|NA S dextransucrase activity BNPNBKBE_00396 1046629.Ssal_00736 8.7e-79 299.7 Bacteria Bacteria COG5263@1,COG5263@2 NA|NA|NA S dextransucrase activity BNPNBKBE_00397 1046629.Ssal_00726 3.1e-305 1053.9 Bacteria Bacteria COG5263@1,COG5263@2 NA|NA|NA S dextransucrase activity BNPNBKBE_00398 904306.HMPREF9192_0370 2.4e-82 311.6 Bacilli vanY 3.4.17.14,3.5.1.28 ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 M00651,M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 Bacteria 1V1F7@1239,4ISN5@91061,COG0739@1,COG0739@2,COG0860@1,COG0860@2,COG1705@1,COG1705@2,COG1876@1,COG1876@2,COG3757@1,COG3757@2 NA|NA|NA M D-alanyl-D-alanine carboxypeptidase BNPNBKBE_00401 435842.HMPREF0848_00088 3.6e-68 264.2 Bacilli 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1UYTM@1239,4HKY4@91061,COG3290@1,COG3290@2 NA|NA|NA T GHKL domain BNPNBKBE_00402 435842.HMPREF0848_00088 1.5e-142 512.3 Bacilli 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1UYTM@1239,4HKY4@91061,COG3290@1,COG3290@2 NA|NA|NA T GHKL domain BNPNBKBE_00403 435842.HMPREF0848_00087 1.8e-133 481.9 Bacteria agrA ko:K07707 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko02022 Bacteria COG3279@1,COG3279@2 NA|NA|NA KT phosphorelay signal transduction system BNPNBKBE_00404 1046629.Ssal_01709 0.0 1418.3 Bacilli 3.4.17.14,3.5.1.28 ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 M00651,M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 Bacteria 1W25V@1239,4HGXW@91061,COG0860@1,COG0860@2,COG1705@1,COG1705@2 NA|NA|NA M GBS Bsp-like repeat BNPNBKBE_00407 1046629.Ssal_01730 0.0 1714.5 Bacilli alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPK6@1239,4H9XC@91061,COG0013@1,COG0013@2 NA|NA|NA J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain BNPNBKBE_00408 435842.HMPREF0848_00077 3e-84 317.8 Bacilli yxjI ko:K21429 ko00000,ko01002 Bacteria 1VBT3@1239,4HH8W@91061,COG4894@1,COG4894@2 NA|NA|NA S LURP-one-related BNPNBKBE_00409 1046629.Ssal_01733 3e-167 594.7 Bacteria prsA 3.1.3.16,5.2.1.8 ko:K01802,ko:K03769,ko:K07533,ko:K20074 ko00000,ko01000,ko01009,ko03110 Bacteria COG0760@1,COG0760@2 NA|NA|NA O peptidyl-prolyl cis-trans isomerase activity BNPNBKBE_00410 1046629.Ssal_01734 6.7e-119 433.3 Bacilli yrrM 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 Bacteria 1UF4M@1239,4HE9E@91061,COG4122@1,COG4122@2 NA|NA|NA S O-Methyltransferase BNPNBKBE_00411 1046629.Ssal_01735 5.9e-214 750.0 Bacilli oxlT ko:K08177 ko00000,ko02000 2.A.1.11 Bacteria 1TPR9@1239,4HB93@91061,COG2223@1,COG2223@2 NA|NA|NA P COG0477 Permeases of the major facilitator superfamily BNPNBKBE_00412 1046629.Ssal_01736 0.0 1200.7 Bacilli pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 ko:K08602 ko00000,ko01000,ko01002 Bacteria 1TP4P@1239,4HA7X@91061,COG1164@1,COG1164@2 NA|NA|NA E oligoendopeptidase F BNPNBKBE_00413 1046629.Ssal_01737 5.2e-165 587.0 Bacilli coiA 3.6.4.12 ko:K03657,ko:K06198 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TRGD@1239,4HFP5@91061,COG4469@1,COG4469@2 NA|NA|NA S Competence protein BNPNBKBE_00414 435842.HMPREF0848_00072 6.4e-279 966.5 Bacteria 2.7.13.3,2.7.7.7,5.4.99.21 ko:K02343,ko:K03407,ko:K06182,ko:K08372,ko:K12065,ko:K16291 ko00230,ko00240,ko01100,ko02020,ko02030,ko03030,ko03430,ko03440,map00230,map00240,map01100,map02020,map02030,map03030,map03430,map03440 M00260,M00506 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko01001,ko01002,ko01011,ko02022,ko02035,ko02044,ko03009,ko03032,ko03400 3.A.7.11.1 Bacteria COG3087@1,COG3087@2 NA|NA|NA D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides BNPNBKBE_00415 435842.HMPREF0848_00071 1e-104 386.3 Firmicutes ko:K07052 ko00000 Bacteria 1VCV8@1239,COG1266@1,COG1266@2 NA|NA|NA S CAAX amino terminal protease family protein BNPNBKBE_00416 1046629.Ssal_01743 5.2e-167 593.6 Bacilli Bacteria 1V53I@1239,4HIEU@91061,COG0583@1,COG0583@2 NA|NA|NA K transcriptional regulator (lysR family) BNPNBKBE_00417 1046629.Ssal_01744 2.9e-159 567.8 Bacilli Bacteria 1TPM1@1239,4H9XJ@91061,COG0656@1,COG0656@2 NA|NA|NA S reductase BNPNBKBE_00418 904306.HMPREF9192_0360 0.0 1334.7 Bacilli metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 ko:K01874,ko:K01890,ko:K06878 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R03660,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPA1@1239,4H9VC@91061,COG0073@1,COG0073@2,COG0143@1,COG0143@2 NA|NA|NA J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation BNPNBKBE_00424 322159.STER_0480 1.2e-186 659.1 Bacilli phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06217 ko00000 Bacteria 1TP35@1239,4HBD5@91061,COG1702@1,COG1702@2 NA|NA|NA T phosphate starvation-inducible protein PhoH BNPNBKBE_00425 1046629.Ssal_01753 2.2e-126 459.1 Bacilli sip Bacteria 1V61Q@1239,4HHT0@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain protein BNPNBKBE_00426 904306.HMPREF9192_0353 3.7e-34 150.2 Bacilli yozE Bacteria 1VFI4@1239,4HR7P@91061,COG4479@1,COG4479@2 NA|NA|NA S Belongs to the UPF0346 family BNPNBKBE_00427 1046629.Ssal_01755 4.2e-158 563.9 Bacilli cvfB ko:K00243 ko00000 Bacteria 1TQ1Z@1239,4HDAZ@91061,COG2996@1,COG2996@2 NA|NA|NA S Protein conserved in bacteria BNPNBKBE_00428 904306.HMPREF9192_0351 6.4e-91 340.1 Bacilli frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02838 ko00000,ko03012 Bacteria 1V1F2@1239,4HFSH@91061,COG0233@1,COG0233@2 NA|NA|NA J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another BNPNBKBE_00429 1046629.Ssal_01757 1.7e-131 475.3 Bacilli pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 iSB619.SA_RS06240 Bacteria 1TPXN@1239,4H9UB@91061,COG0528@1,COG0528@2 NA|NA|NA F Catalyzes the reversible phosphorylation of UMP to UDP BNPNBKBE_00430 1046629.Ssal_01758 4.7e-211 740.3 Bacilli sptS 2.7.13.3 ko:K11328 ko02020,map02020 M00464 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1UHQH@1239,4HAHG@91061,COG0642@1,COG0642@2 NA|NA|NA T Histidine kinase BNPNBKBE_00431 1046629.Ssal_01760 6e-115 420.2 Bacilli Bacteria 1TPU2@1239,4HG2E@91061,COG0745@1,COG0745@2 NA|NA|NA T response regulator BNPNBKBE_00432 904306.HMPREF9192_0347 7.4e-112 409.8 Bacilli 2.7.6.5 ko:K00951,ko:K07816 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 1TQ2F@1239,4HTR5@91061,COG2357@1,COG2357@2 NA|NA|NA S Region found in RelA / SpoT proteins BNPNBKBE_00433 1046629.Ssal_01762 1.4e-110 405.6 Bacilli Bacteria 1VF01@1239,4HPKN@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) family BNPNBKBE_00434 1046629.Ssal_01763 0.0 1103.2 Bacilli lmrA2 ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_00435 1046629.Ssal_01764 7.2e-309 1065.8 Bacilli lmrA1 ko:K02021,ko:K06147,ko:K06148,ko:K18887 ko02010,map02010 M00706 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 Bacteria 1TP0B@1239,4H9SC@91061,COG1132@1,COG1132@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_00436 264199.stu0432 2.6e-74 284.6 Bacteria Bacteria COG1846@1,COG1846@2 NA|NA|NA K DNA-binding transcription factor activity BNPNBKBE_00437 1046629.Ssal_01766 7.9e-70 269.6 Bacilli def_1 3.5.1.31,3.5.1.88 ko:K01450,ko:K01462 ko00270,ko00630,map00270,map00630 R00653 RC00165,RC00323 ko00000,ko00001,ko01000 Bacteria 1V73T@1239,4HGYC@91061,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins BNPNBKBE_00438 1046629.Ssal_01767 1.7e-269 934.9 Bacilli Bacteria 1VS0Z@1239,4HJQE@91061,COG5617@1,COG5617@2 NA|NA|NA S Psort location CytoplasmicMembrane, score BNPNBKBE_00439 904306.HMPREF9192_0340 1.4e-256 891.7 Bacilli gdhA 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 R00248 RC00006,RC02799 ko00000,ko00001,ko01000 Bacteria 1TP45@1239,4HAEI@91061,COG0334@1,COG0334@2 NA|NA|NA E Belongs to the Glu Leu Phe Val dehydrogenases family BNPNBKBE_00440 1046629.Ssal_01769 1e-153 549.3 Bacilli nadD 2.7.1.22,2.7.7.1,2.7.7.18,3.6.1.55 ko:K00969,ko:K03574,ko:K06211 ko00760,ko01100,map00760,map01100 M00115 R00137,R02324,R03005 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko03000,ko03400 iIT341.HP1337 Bacteria 1TQ29@1239,4HBZT@91061,COG1057@1,COG1057@2,COG3172@1,COG3172@2 NA|NA|NA H adenylyltransferase BNPNBKBE_00441 904306.HMPREF9192_0338 2.6e-128 465.3 Bacilli 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 1TST7@1239,4HEFP@91061,COG1051@1,COG1051@2 NA|NA|NA F AdP-ribose pyrophosphatase BNPNBKBE_00442 1123298.KB904062_gene886 5e-26 124.4 Bacteria Bacteria COG3247@1,COG3247@2 NA|NA|NA U response to pH BNPNBKBE_00443 1046629.Ssal_01772 0.0 1184.1 Bacilli yfmR ko:K15738 ko00000,ko02000 3.A.1.120.6 Bacteria 1TPAX@1239,4H9TK@91061,COG0488@1,COG0488@2 NA|NA|NA S abc transporter atp-binding protein BNPNBKBE_00444 904306.HMPREF9192_0334 1.7e-218 765.0 Bacilli cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 1TQ2A@1239,4HB2W@91061,COG0617@1,COG0617@2 NA|NA|NA J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate BNPNBKBE_00445 1046629.Ssal_01774 2.5e-138 498.0 Bacilli dapB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 iJN678.dapB,iNJ661.Rv2773c,iYO844.BSU22490 Bacteria 1TR9D@1239,4HA5X@91061,COG0289@1,COG0289@2 NA|NA|NA E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate BNPNBKBE_00446 1046629.Ssal_01775 2.8e-146 524.6 Bacilli XK27_08360 Bacteria 1TRM7@1239,4HVKJ@91061,COG1307@1,COG1307@2 NA|NA|NA S EDD domain protein, DegV family BNPNBKBE_00447 1046629.Ssal_01776 5e-63 246.9 Bacilli WQ51_03320 Bacteria 1VHA6@1239,4HPTC@91061,COG4835@1,COG4835@2 NA|NA|NA S cog cog4835 BNPNBKBE_00448 322159.STER_0457 2.7e-131 474.6 Bacteria ydaF_2 Bacteria COG1670@1,COG1670@2 NA|NA|NA J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins BNPNBKBE_00449 1046629.Ssal_01778 1.5e-46 191.8 Bacilli rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6HW@1239,4HIMN@91061,COG0211@1,COG0211@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL27 family BNPNBKBE_00450 264199.stu0417 4.5e-49 200.3 Bacilli rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9YH@1239,4HIGK@91061,COG0261@1,COG0261@2 NA|NA|NA J This protein binds to 23S rRNA in the presence of protein L20 BNPNBKBE_00451 1046629.Ssal_01780 6.2e-83 313.5 Bacteria 2.3.1.128 ko:K03789 ko00000,ko01000,ko03009 Bacteria COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase BNPNBKBE_00452 904306.HMPREF9192_0325 7.7e-252 875.9 Firmicutes gtf2 Bacteria 1TQZR@1239,COG0438@1,COG0438@2 NA|NA|NA M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1 BNPNBKBE_00453 1046629.Ssal_01782 3.1e-289 1000.3 Bacilli gtf1 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1TR6K@1239,4HGDG@91061,COG0438@1,COG0438@2 NA|NA|NA M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon BNPNBKBE_00454 904306.HMPREF9192_0323 9.7e-225 785.8 Bacilli thiI GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07461 ko00000,ko00001,ko01000,ko03016 iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307 Bacteria 1TPNW@1239,4HAV9@91061,COG0301@1,COG0301@2 NA|NA|NA H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS BNPNBKBE_00455 1046629.Ssal_01786 1.7e-210 738.4 Bacilli iscS2 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TP21@1239,4HAEE@91061,COG1104@1,COG1104@2 NA|NA|NA E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes BNPNBKBE_00457 1046629.Ssal_01788 3.3e-228 797.3 Bacilli folC 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0166 Bacteria 1TPX5@1239,4HBJM@91061,COG0285@1,COG0285@2 NA|NA|NA H Belongs to the folylpolyglutamate synthase family BNPNBKBE_00458 1046629.Ssal_00089 7.3e-53 213.0 Bacilli rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02890 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6PU@1239,4HIK2@91061,COG0091@1,COG0091@2 NA|NA|NA J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome BNPNBKBE_00459 1046629.Ssal_00090 1.6e-117 428.7 Bacilli rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02982 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPCP@1239,4HAUR@91061,COG0092@1,COG0092@2 NA|NA|NA J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation BNPNBKBE_00460 1046629.Ssal_00091 1.1e-71 275.8 Bacilli rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02878 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1AY@1239,4HFPN@91061,COG0197@1,COG0197@2 NA|NA|NA J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs BNPNBKBE_00461 1046629.Ssal_00092 3.5e-26 123.6 Bacilli rpmC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02904 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEME@1239,4HNUP@91061,COG0255@1,COG0255@2 NA|NA|NA J Belongs to the universal ribosomal protein uL29 family BNPNBKBE_00462 1000570.HMPREF9966_1572 1.9e-15 87.4 Bacilli rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02961 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9YC@1239,4HKDN@91061,COG0186@1,COG0186@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA BNPNBKBE_00463 1069533.Sinf_0130 5.4e-124 450.3 Bacilli ko:K07483 ko00000 Bacteria 1V1QC@1239,4HH7E@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain BNPNBKBE_00464 1069533.Sinf_0131 5e-146 523.9 Bacilli Bacteria 1TQEG@1239,4HD6M@91061,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain protein BNPNBKBE_00465 571.MC52_00430 5.9e-252 876.3 Gammaproteobacteria merA GO:0000302,GO:0000305,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0019725,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901530,GO:1901700,GO:1990748 1.16.1.1,1.8.1.7 ko:K00383,ko:K00520,ko:K21739 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1MU2U@1224,1RQTU@1236,COG1249@1,COG1249@2 NA|NA|NA C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family BNPNBKBE_00466 435842.HMPREF0848_00169 2.1e-21 107.5 Bacilli ko:K19165 ko00000,ko02048 Bacteria 1VF6A@1239,2E4DC@1,32Z8R@2,4I1RQ@91061 NA|NA|NA S Antitoxin component of a toxin-antitoxin (TA) module BNPNBKBE_00468 1046629.Ssal_01136 4.9e-217 760.4 Bacilli acoC 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TR5N@1239,4HDFT@91061,COG0508@1,COG0508@2 NA|NA|NA C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex BNPNBKBE_00469 1046629.Ssal_01137 1.4e-181 642.1 Bacilli acoB 1.2.4.1,1.2.4.4 ko:K00162,ko:K11381,ko:K21417 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TP3J@1239,4HAP6@91061,COG0022@1,COG0022@2 NA|NA|NA C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit BNPNBKBE_00470 1046629.Ssal_01138 1.5e-183 648.7 Bacilli acoA 1.2.4.1,1.2.4.4 ko:K00161,ko:K11381,ko:K21416 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TQDG@1239,4HBEA@91061,COG1071@1,COG1071@2 NA|NA|NA C Dehydrogenase E1 component BNPNBKBE_00471 1046629.Ssal_01139 2.1e-198 698.4 Bacteria hpk9 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria COG3290@1,COG3290@2 NA|NA|NA T protein histidine kinase activity BNPNBKBE_00472 1046629.Ssal_01140 9.3e-226 789.3 Bacteria 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria COG3290@1,COG3290@2 NA|NA|NA T protein histidine kinase activity BNPNBKBE_00473 435842.HMPREF0848_00629 0.0 1159.4 Bacilli Bacteria 1TS3Q@1239,4HF7D@91061,COG4907@1,COG4907@2 NA|NA|NA S the current gene model (or a revised gene model) may contain a frame shift BNPNBKBE_00474 1046629.Ssal_01152 9.1e-234 815.8 Bacilli pyrC GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPQM@1239,4HA90@91061,COG0044@1,COG0044@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily BNPNBKBE_00475 904306.HMPREF9192_1707 4.1e-121 440.7 Bacilli ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPSN@1239,4HBTR@91061,COG0692@1,COG0692@2 NA|NA|NA L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine BNPNBKBE_00476 1046629.Ssal_01154 2.1e-211 741.5 Bacilli yeaB Bacteria 1TSGY@1239,4H9WP@91061,COG0053@1,COG0053@2,COG4994@1,COG4994@2 NA|NA|NA K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family BNPNBKBE_00477 1046629.Ssal_01155 5.8e-247 859.8 Bacilli dacA1 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1TQN0@1239,4HD0P@91061,COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family BNPNBKBE_00478 1046629.Ssal_01156 6.9e-153 546.6 Bacilli rssA Bacteria 1TQ9W@1239,4HCHJ@91061,COG4667@1,COG4667@2 NA|NA|NA S Phospholipase, patatin family BNPNBKBE_00479 904306.HMPREF9192_1701 5e-100 370.5 Bacilli estA Bacteria 1VHUN@1239,4IPN1@91061,COG2755@1,COG2755@2 NA|NA|NA E Lysophospholipase L1 and related esterases BNPNBKBE_00480 1046629.Ssal_01158 6.8e-279 966.1 Bacilli ko:K03688 ko00000 Bacteria 1TPIV@1239,4HBW3@91061,COG0661@1,COG0661@2 NA|NA|NA S unusual protein kinase BNPNBKBE_00481 1046629.Ssal_01159 4.1e-38 163.7 Bacilli Bacteria 1VK6K@1239,4HRS5@91061,COG3937@1,COG3937@2 NA|NA|NA S granule-associated protein BNPNBKBE_00482 1046629.Ssal_01160 9.2e-283 978.8 Bacilli bglH 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family BNPNBKBE_00483 1046629.Ssal_01161 1.2e-195 689.1 Bacilli Bacteria 1TQBF@1239,4HGFS@91061,COG0628@1,COG0628@2 NA|NA|NA S hmm pf01594 BNPNBKBE_00484 904306.HMPREF9192_1694 4.2e-104 384.0 Bacilli Bacteria 1UXY8@1239,4HFD9@91061,COG0406@1,COG0406@2 NA|NA|NA G Belongs to the phosphoglycerate mutase family BNPNBKBE_00485 435842.HMPREF0848_00618 1.2e-106 392.5 Bacilli Bacteria 1UXY8@1239,4HFD9@91061,COG0406@1,COG0406@2 NA|NA|NA G Belongs to the phosphoglycerate mutase family BNPNBKBE_00486 904306.HMPREF9192_1692 4.8e-108 397.1 Bacilli pgm Bacteria 1UXY8@1239,4HFD9@91061,COG0406@1,COG0406@2 NA|NA|NA G Belongs to the phosphoglycerate mutase family BNPNBKBE_00487 1046629.Ssal_01165 9e-142 509.6 Bacilli supH 3.1.3.102,3.1.3.104 ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V1SQ@1239,4IPTG@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase BNPNBKBE_00489 1069533.Sinf_0729 1.5e-186 658.7 Bacilli wbbI GO:0003674,GO:0003824,GO:0008194,GO:0008378,GO:0008921,GO:0016740,GO:0016757,GO:0016758,GO:0035250 iAF1260.b2034,iBWG_1329.BWG_1824,iECDH10B_1368.ECDH10B_2184,iECDH1ME8569_1439.ECDH1ME8569_1971,iECSF_1327.ECSF_1923,iEcDH1_1363.EcDH1_1623,iJO1366.b2034,iY75_1357.Y75_RS10645 Bacteria 1UZFG@1239,4ISTK@91061,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups BNPNBKBE_00490 904306.HMPREF9192_1687 3e-184 651.0 Bacilli sacB ko:K20444 ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria 1TPG9@1239,4HGEP@91061,COG0438@1,COG0438@2 NA|NA|NA M Stealth protein CR2, conserved region 2 BNPNBKBE_00491 1069533.Sinf_0727 1.8e-214 751.5 Bacilli glf GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0071554,GO:0071766,GO:0071840,GO:0071944,GO:0097159,GO:1901265,GO:1901363 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 iNJ661.Rv3809c Bacteria 1TQB9@1239,4HB5F@91061,COG0562@1,COG0562@2 NA|NA|NA M UDP-galactopyranose mutase BNPNBKBE_00492 904306.HMPREF9192_1685 8.3e-244 849.4 Bacilli epsU Bacteria 1TP7R@1239,4HC84@91061,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein BNPNBKBE_00493 862970.SAIN_1720 4.8e-173 614.0 Bacilli Bacteria 1VC7Z@1239,2BVGB@1,32U6R@2,4HNDJ@91061 NA|NA|NA BNPNBKBE_00494 862970.SAIN_1721 5.2e-160 570.5 Bacilli Bacteria 1V0TF@1239,4HN74@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 BNPNBKBE_00495 862970.SAIN_1722 8.5e-163 579.7 Bacilli Bacteria 1V0TF@1239,4ISVG@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase, group 2 family protein BNPNBKBE_00496 904306.HMPREF9192_1682 1.4e-149 535.8 Bacilli Bacteria 1V6BK@1239,28PSK@1,2ZCE3@2,4HMNC@91061 NA|NA|NA BNPNBKBE_00497 435842.HMPREF0848_00609 1.2e-120 439.1 Bacilli Z012_10770 Bacteria 1V8R9@1239,4HW77@91061,COG3955@1,COG3955@2 NA|NA|NA M Domain of unknown function (DUF1919) BNPNBKBE_00498 1116231.SMA_0863 2.2e-210 738.0 Bacilli wcoF Bacteria 1TR6R@1239,4HEIZ@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase, group 1 family protein BNPNBKBE_00499 904306.HMPREF9192_1679 4.3e-222 776.9 Bacilli rgpAc ko:K12996 ko00000,ko01000,ko01003,ko01005 GT4 Bacteria 1TR0Y@1239,4IPU2@91061,COG0438@1,COG0438@2 NA|NA|NA M group 1 family protein BNPNBKBE_00500 264199.stu1108 8.1e-252 875.9 Bacilli cpsE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1TP7M@1239,4HB3Z@91061,COG2148@1,COG2148@2 NA|NA|NA M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase BNPNBKBE_00501 322159.STER_1068 5e-115 420.6 Bacilli cpsD Bacteria 1TS4R@1239,4HCEN@91061,COG0489@1,COG0489@2 NA|NA|NA D COG0489 ATPases involved in chromosome partitioning BNPNBKBE_00502 435842.HMPREF0848_00604 1.2e-110 406.0 Bacilli cps4C Bacteria 1UZCR@1239,4HE26@91061,COG3944@1,COG3944@2 NA|NA|NA M biosynthesis protein BNPNBKBE_00503 322159.STER_1070 6.8e-133 479.9 Bacilli cpsB 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1TQ1T@1239,4HDZR@91061,COG4464@1,COG4464@2 NA|NA|NA GM Capsular polysaccharide biosynthesis protein BNPNBKBE_00504 322159.STER_1071 1e-249 869.0 Bacilli cps4A Bacteria 1TR1B@1239,4HDRS@91061,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-like function transcriptional attenuator common domain protein BNPNBKBE_00505 435842.HMPREF0848_00601 4.9e-128 463.8 Bacilli deoD GO:0003674,GO:0003824,GO:0004731,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009164,GO:0009987,GO:0015949,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0019686,GO:0033554,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 2.4.2.1,2.4.2.28 ko:K00772,ko:K03784 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 M00034 R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122,RC02819 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1997,iB21_1397.B21_04226,iE2348C_1286.E2348C_4682,iEC042_1314.EC042_4881,iECABU_c1320.ECABU_c50190,iECBD_1354.ECBD_3636,iECB_1328.ECB_04260,iECD_1391.ECD_04260,iECED1_1282.ECED1_5255,iECIAI39_1322.ECIAI39_4916,iECNA114_1301.ECNA114_4626,iECO26_1355.ECO26_5590,iECOK1_1307.ECOK1_4950,iECP_1309.ECP_4768,iEcolC_1368.EcolC_3672,iLF82_1304.LF82_0467,iNRG857_1313.NRG857_22170,iPC815.YPO0440,iSFV_1184.SFV_4418,iSF_1195.SF4416,iSFxv_1172.SFxv_4809,iS_1188.S4687,iUMN146_1321.UM146_22680,iUMNK88_1353.UMNK88_5303,iUTI89_1310.UTI89_C5155,ic_1306.c5468 Bacteria 1TQPG@1239,4HADM@91061,COG0813@1,COG0813@2 NA|NA|NA F purine nucleoside phosphorylase BNPNBKBE_00506 1046629.Ssal_01031 6.9e-130 469.9 Bacilli yfeJ 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1V97T@1239,4HIKV@91061,COG0518@1,COG0518@2 NA|NA|NA F glutamine amidotransferase BNPNBKBE_00507 435842.HMPREF0848_00599 3.7e-163 581.3 Firmicutes clcA_2 ko:K03281 ko00000 2.A.49 Bacteria 1V07H@1239,COG0038@1,COG0038@2 NA|NA|NA P chloride BNPNBKBE_00508 1123314.AUIO01000012_gene1814 2.4e-50 205.7 Bacteria ko:K03744 ko00000 Bacteria COG1704@1,COG1704@2 NA|NA|NA S LemA family BNPNBKBE_00509 1046629.Ssal_01029 1.7e-148 531.9 Bacilli punA 2.4.2.1 ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 Bacteria 1TQ37@1239,4HABP@91061,COG0005@1,COG0005@2 NA|NA|NA F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate BNPNBKBE_00510 1046629.Ssal_01028 3.6e-86 324.3 Bacilli Bacteria 1V426@1239,4HI2S@91061,COG3797@1,COG3797@2 NA|NA|NA S Protein of unknown function (DUF1697) BNPNBKBE_00511 435842.HMPREF0848_00596 6e-235 819.7 Bacilli deoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008973,GO:0016853,GO:0016866,GO:0016868,GO:0044424,GO:0044444,GO:0044464 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 R01057,R02749 RC00408 ko00000,ko00001,ko01000 Bacteria 1TP70@1239,4H9RU@91061,COG1015@1,COG1015@2 NA|NA|NA G Phosphotransfer between the C1 and C5 carbon atoms of pentose BNPNBKBE_00512 1046629.Ssal_01026 4e-119 434.1 Bacilli rpiA GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,2.7.1.15,5.3.1.6 ko:K00851,ko:K00852,ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01051,R01056,R01737,R02750 RC00002,RC00017,RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria 1V1DB@1239,4HFQ7@91061,COG0120@1,COG0120@2 NA|NA|NA G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate BNPNBKBE_00513 1046629.Ssal_01025 2.1e-252 879.0 Bacilli ko:K13732 ko05100,map05100 ko00000,ko00001 Bacteria 1VU2V@1239,4HU5W@91061,COG3266@1,COG3266@2 NA|NA|NA V Glucan-binding protein C BNPNBKBE_00514 888048.HMPREF8577_1453 7.2e-226 791.2 Bacilli Bacteria 1VU2V@1239,4HU5W@91061,COG3266@1,COG3266@2 NA|NA|NA V Glucan-binding protein C BNPNBKBE_00515 1046629.Ssal_01185 2e-106 391.7 Bacilli ung2 3.2.2.27 ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1F8@1239,4HFVS@91061,COG1573@1,COG1573@2 NA|NA|NA L Uracil-DNA glycosylase BNPNBKBE_00516 1046629.Ssal_01186 5e-273 946.4 Bacilli pepV 3.5.1.18 ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 M00016 R00899,R02734,R04951 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPEG@1239,4HC14@91061,COG0624@1,COG0624@2 NA|NA|NA E Dipeptidase BNPNBKBE_00517 1046629.Ssal_01187 4.9e-27 126.3 Bacilli dmpI GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 Bacteria 1VKD5@1239,4HRBS@91061,COG1942@1,COG1942@2 NA|NA|NA G Belongs to the 4-oxalocrotonate tautomerase family BNPNBKBE_00518 888808.HMPREF9380_0391 3.3e-07 62.8 Streptococcus sanguinis Bacteria 1UADF@1239,1WS6G@1305,29RQS@1,30CUC@2,4IKRQ@91061 NA|NA|NA BNPNBKBE_00521 904306.HMPREF9192_1907 3.8e-113 414.1 Bacilli nudL GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 Bacteria 1V6SF@1239,4HG46@91061,COG0494@1,COG0494@2 NA|NA|NA L hydrolase BNPNBKBE_00522 435842.HMPREF0848_01721 5e-51 206.8 Bacilli ko:K10947 ko00000,ko03000 Bacteria 1VIVQ@1239,4IR4R@91061,COG1695@1,COG1695@2 NA|NA|NA K transcriptional regulator, PadR family BNPNBKBE_00523 904306.HMPREF9192_1905 4e-59 234.6 Bacilli XK27_06920 Bacteria 1VBG6@1239,4HSRQ@91061,COG4709@1,COG4709@2 NA|NA|NA S Protein of unknown function (DUF1700) BNPNBKBE_00524 904306.HMPREF9192_1904 1.6e-101 375.9 Firmicutes Bacteria 1VGGF@1239,COG3595@1,COG3595@2 NA|NA|NA S Putative adhesin BNPNBKBE_00525 904306.HMPREF9192_1903 3.9e-161 575.5 Bacilli XK27_06930 ko:K01421 ko00000 Bacteria 1TQ15@1239,4H9T9@91061,COG1511@1,COG1511@2 NA|NA|NA V domain protein BNPNBKBE_00526 1046629.Ssal_00033 1.3e-93 349.0 Bacteria XK27_06935 Bacteria COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator BNPNBKBE_00527 1046629.Ssal_00032 2.2e-52 211.5 Firmicutes ypaA ko:K08987 ko00000 Bacteria 1VAEU@1239,COG3759@1,COG3759@2 NA|NA|NA M Membrane BNPNBKBE_00528 1123318.KB904633_gene1270 1.1e-10 72.0 Bacilli Bacteria 1W3FT@1239,2914P@1,2ZNS1@2,4I23Q@91061 NA|NA|NA BNPNBKBE_00529 1046629.Ssal_00030 5.8e-109 400.2 Bacilli rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 ko:K02986 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TR0J@1239,4HAC9@91061,COG0522@1,COG0522@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit BNPNBKBE_00530 1046629.Ssal_00029 1.8e-47 194.9 Bacilli veg Bacteria 1VPZY@1239,4HSFF@91061,COG4466@1,COG4466@2 NA|NA|NA S Biofilm formation stimulator VEG BNPNBKBE_00531 1046629.Ssal_00028 6.5e-246 856.3 Bacilli dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 1TPCT@1239,4H9Y8@91061,COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication BNPNBKBE_00532 1046629.Ssal_00027 2.2e-73 281.6 Bacilli rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6QG@1239,4HIKJ@91061,COG0359@1,COG0359@2 NA|NA|NA J binds to the 23S rRNA BNPNBKBE_00533 904306.HMPREF9192_1894 0.0 1215.7 Bacilli yybT Bacteria 1TPGP@1239,4HBVH@91061,COG3887@1,COG3887@2 NA|NA|NA T signaling protein consisting of a modified GGDEF domain and a DHH domain BNPNBKBE_00534 1046629.Ssal_00025 0.0 1232.2 Bacilli gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 ko:K03495 R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 Bacteria 1TQ4B@1239,4HA6S@91061,COG0445@1,COG0445@2 NA|NA|NA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 BNPNBKBE_00535 467705.SGO_0023 2.5e-96 358.2 Bacilli yvbG ko:K05595 ko00000,ko02000 2.A.95.1 Bacteria 1V81W@1239,4HIUV@91061,COG2095@1,COG2095@2 NA|NA|NA U UPF0056 membrane protein BNPNBKBE_00536 1046629.Ssal_00023 5.6e-219 766.5 Bacilli mnmA GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 Bacteria 1TPIZ@1239,4HBJ6@91061,COG0482@1,COG0482@2 NA|NA|NA J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 BNPNBKBE_00537 1046629.Ssal_00022 4.6e-305 1053.1 Bacilli Bacteria 1V0XZ@1239,4HEBN@91061,COG4485@1,COG4485@2 NA|NA|NA S Bacterial membrane protein, YfhO BNPNBKBE_00538 1046629.Ssal_00021 9.3e-63 246.9 Bacilli isaA ko:K21687 ko00000 GH23 Bacteria 1VGPA@1239,4HP1I@91061,COG0741@1,COG0741@2 NA|NA|NA M Immunodominant staphylococcal antigen A BNPNBKBE_00539 1046629.Ssal_00020 1.9e-61 242.3 Bacilli lytE Bacteria 1VA10@1239,4HMUH@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain protein BNPNBKBE_00540 264199.stu2007 2.2e-132 478.4 Bacilli ecfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 ko:K02008,ko:K16783,ko:K16785 ko02010,map02010 M00245,M00246,M00581,M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TQ0E@1239,4H9VT@91061,COG0619@1,COG0619@2 NA|NA|NA P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates BNPNBKBE_00541 1046629.Ssal_00018 1.4e-150 538.9 Bacilli ecfA2 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008144,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032217,GO:0032218,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035461,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0097159,GO:0097367,GO:0098656,GO:1901265,GO:1901363 3.6.3.55 ko:K02068,ko:K06857,ko:K16784,ko:K16786,ko:K16787 ko02010,map02010 M00186,M00211,M00581,M00582 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35,3.A.1.6.2,3.A.1.6.4 Bacteria 1TPH8@1239,4HA7T@91061,COG1122@1,COG1122@2 NA|NA|NA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates BNPNBKBE_00542 1046629.Ssal_00017 7.7e-149 533.1 Bacilli ecfA1 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 ko:K16784,ko:K16786,ko:K16787 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPH8@1239,4H9R8@91061,COG1122@1,COG1122@2 NA|NA|NA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates BNPNBKBE_00543 1046629.Ssal_00016 5.9e-89 333.6 Bacilli pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 iSB619.SA_RS06365 Bacteria 1V6PJ@1239,4HCEX@91061,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family BNPNBKBE_00544 1046629.Ssal_00015 5.4e-129 467.2 Bacteria ko:K15539 ko00000 Bacteria COG1426@1,COG1426@2 NA|NA|NA S sequence-specific DNA binding BNPNBKBE_00545 1046629.Ssal_00014 4.6e-233 813.5 Bacilli ymfH ko:K07263 ko00000,ko01000,ko01002 Bacteria 1TP5I@1239,4H9YG@91061,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 BNPNBKBE_00546 1046629.Ssal_00013 5.6e-228 796.6 Bacilli ymfF Bacteria 1TPN6@1239,4H9P5@91061,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 BNPNBKBE_00547 1046629.Ssal_00012 6.4e-58 229.9 Bacilli yaaA GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K14761 ko00000,ko03009 Bacteria 1VKF4@1239,4HRX5@91061,COG2501@1,COG2501@2 NA|NA|NA S S4 domain protein YaaA BNPNBKBE_00548 1046629.Ssal_00011 1.2e-200 705.7 Bacilli recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1TP9U@1239,4HA0W@91061,COG1195@1,COG1195@2 NA|NA|NA L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP BNPNBKBE_00549 1046629.Ssal_00010 1.1e-273 948.7 Bacilli guaB GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027 Bacteria 1TNZ1@1239,4H9V3@91061,COG0516@1,COG0516@2,COG0517@1,COG0517@2 NA|NA|NA F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth BNPNBKBE_00550 1046629.Ssal_00009 7.2e-189 666.4 Bacilli trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPY7@1239,4HA1K@91061,COG0180@1,COG0180@2 NA|NA|NA J Tryptophanyl-tRNA synthetase BNPNBKBE_00551 1046629.Ssal_00008 9.3e-153 546.2 Bacilli yvjA Bacteria 1TR9J@1239,4H9N6@91061,COG1284@1,COG1284@2 NA|NA|NA S membrane BNPNBKBE_00552 904306.HMPREF9192_1872 1.1e-305 1055.0 Bacilli ybiT GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896 ko:K06158 ko00000,ko03012 Bacteria 1TPW0@1239,4HATH@91061,COG0488@1,COG0488@2 NA|NA|NA S abc transporter atp-binding protein BNPNBKBE_00553 1046629.Ssal_00006 0.0 1610.5 Bacilli XK27_10405 Bacteria 1TRR1@1239,4HCR9@91061,COG4485@1,COG4485@2 NA|NA|NA S Bacterial membrane protein YfhO BNPNBKBE_00557 1046629.Ssal_00005 1.7e-117 428.7 Bacteria yoaK Bacteria COG3619@1,COG3619@2 NA|NA|NA S Protein of unknown function (DUF1275) BNPNBKBE_00558 1046629.Ssal_00004 6.8e-81 306.6 Bacilli rlmH 2.1.1.177 ko:K00783 ko00000,ko01000,ko03009 Bacteria 1V3JM@1239,4HFP8@91061,COG1576@1,COG1576@2 NA|NA|NA J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA BNPNBKBE_00559 1046629.Ssal_00003 1.5e-201 708.8 Bacilli htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04691,ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1TRM8@1239,4HA31@91061,COG0265@1,COG0265@2 NA|NA|NA O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain' BNPNBKBE_00560 1046629.Ssal_00002 3.2e-133 481.1 Bacilli parB ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 1TQ2B@1239,4H9TB@91061,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family BNPNBKBE_00561 1046629.Ssal_00001 3.2e-253 880.6 Bacilli dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 1TPV7@1239,4H9MW@91061,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids BNPNBKBE_00562 904306.HMPREF9192_1861 4.2e-198 697.2 Bacilli dnaN 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TQ7J@1239,4H9TF@91061,COG0592@1,COG0592@2 NA|NA|NA L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria BNPNBKBE_00563 1046629.Ssal_02164 3.2e-29 133.7 Bacilli yyzM Bacteria 1VEQ7@1239,4HNHU@91061,COG4481@1,COG4481@2 NA|NA|NA S Protein conserved in bacteria BNPNBKBE_00564 1046629.Ssal_02163 1.1e-203 715.7 Bacilli ychF GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 ko:K06942 ko00000,ko03009 Bacteria 1TPRK@1239,4H9SQ@91061,COG0012@1,COG0012@2 NA|NA|NA J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner BNPNBKBE_00565 1046629.Ssal_02162 5.2e-104 383.6 Bacilli pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 1V3NB@1239,4HH2Z@91061,COG0193@1,COG0193@2 NA|NA|NA J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis BNPNBKBE_00566 1046629.Ssal_02161 0.0 2244.2 Bacilli mfd ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPF1@1239,4H9NB@91061,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site BNPNBKBE_00567 1046629.Ssal_02160 2.2e-39 167.9 Bacilli yabO GO:0008150,GO:0040007 Bacteria 1VEI5@1239,4HKJJ@91061,COG1188@1,COG1188@2 NA|NA|NA J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) BNPNBKBE_00568 322159.STER_0009 3e-60 237.7 Bacilli divIC ko:K05589,ko:K13052 ko00000,ko03036 Bacteria 1VKC5@1239,4HR53@91061,COG2919@1,COG2919@2 NA|NA|NA D Septum formation initiator BNPNBKBE_00570 1046629.Ssal_02157 3.2e-234 817.4 Bacilli XK27_09285 3.5.2.6 ko:K01467,ko:K17836 ko00311,ko01130,ko01501,ko02020,map00311,map01130,map01501,map02020 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1VGXR@1239,4IPWW@91061,COG2367@1,COG2367@2 NA|NA|NA V Beta-lactamase enzyme family BNPNBKBE_00571 1046629.Ssal_02156 7.7e-233 812.8 Bacilli tilS 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 1TPXP@1239,4H9ZM@91061,COG0037@1,COG0037@2 NA|NA|NA D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine BNPNBKBE_00572 1046629.Ssal_02155 2e-97 361.7 Bacilli hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,6.3.4.19 ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000,ko03016 Bacteria 1V1C9@1239,4HFZ2@91061,COG0634@1,COG0634@2 NA|NA|NA F Belongs to the purine pyrimidine phosphoribosyltransferase family BNPNBKBE_00573 1046629.Ssal_02154 0.0 1241.9 Bacilli ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 ko:K03798 M00742 ko00000,ko00002,ko01000,ko01002,ko03110 Bacteria 1TPTV@1239,4HAJB@91061,COG0465@1,COG0465@2 NA|NA|NA O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins BNPNBKBE_00574 563038.HMPREF0851_01447 2e-46 192.2 Bacilli Bacteria 1W3A8@1239,2DEIC@1,2ZN3X@2,4HZMP@91061 NA|NA|NA BNPNBKBE_00575 904306.HMPREF9192_0784 0.0 1463.0 Bacilli ctpE ko:K12952 ko00000,ko01000 3.A.3.23 Bacteria 1TPF5@1239,4H9ZI@91061,COG0474@1,COG0474@2 NA|NA|NA P E1-E2 ATPase BNPNBKBE_00576 1046629.Ssal_00451 2.2e-58 231.5 Bacilli Bacteria 1VCIA@1239,2C4MC@1,32RSW@2,4HKKA@91061 NA|NA|NA BNPNBKBE_00577 322159.STER_1555 2e-40 171.4 Bacteria pchB 2.5.1.19,4.2.1.10,4.2.99.21,5.4.99.5 ko:K00800,ko:K03785,ko:K04092,ko:K04782 ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230 M00022,M00024,M00025 R01715,R03084,R03460,R06602 RC00350,RC00848,RC01549,RC02148,RC03116 ko00000,ko00001,ko00002,ko01000 Bacteria COG1605@1,COG1605@2 NA|NA|NA E Chorismate mutase BNPNBKBE_00578 904306.HMPREF9192_0786 6.3e-257 892.9 Bacilli trpE GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQAP@1239,4HB31@91061,COG0147@1,COG0147@2 NA|NA|NA EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia BNPNBKBE_00579 1046629.Ssal_00458 1.4e-104 385.6 Bacilli trpG 2.4.2.18,2.6.1.85,4.1.3.27 ko:K00766,ko:K01658,ko:K01664,ko:K13497 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01073,R01716 RC00010,RC00440,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 1V4RM@1239,4HHD8@91061,COG0512@1,COG0512@2 NA|NA|NA EH anthranilate BNPNBKBE_00580 904306.HMPREF9192_0788 1.3e-179 635.6 Bacilli trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP8U@1239,4H9KQ@91061,COG0547@1,COG0547@2 NA|NA|NA F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) BNPNBKBE_00581 1046629.Ssal_00461 3.6e-132 477.6 Bacilli trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K01817,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR94@1239,4HG9K@91061,COG0134@1,COG0134@2 NA|NA|NA E Belongs to the TrpC family BNPNBKBE_00582 435842.HMPREF0848_01210 1.5e-98 365.5 Bacilli trpF GO:0000162,GO:0003674,GO:0003824,GO:0004425,GO:0004640,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48,4.2.1.160,4.2.1.20,5.3.1.24 ko:K01696,ko:K01817,ko:K13498,ko:K22100 ko00260,ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map00790,map01100,map01110,map01130,map01230 M00023,M00840 R00674,R02340,R02722,R03508,R03509,R11072 RC00209,RC00210,RC00700,RC00701,RC00944,RC00945,RC02868,RC03343 ko00000,ko00001,ko00002,ko01000 iJN678.trpF,iPC815.YPO2205,iSBO_1134.SBO_1804,iSDY_1059.SDY_1330 Bacteria 1V6Y0@1239,4HK18@91061,COG0135@1,COG0135@2 NA|NA|NA E belongs to the TrpF family BNPNBKBE_00583 1046629.Ssal_00464 5.8e-230 803.1 Bacilli trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20,5.3.1.24 ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722,R03509 RC00209,RC00210,RC00700,RC00701,RC00945,RC02868 ko00000,ko00001,ko00002,ko01000 iYO844.BSU22640 Bacteria 1TPI3@1239,4H9WC@91061,COG0133@1,COG0133@2 NA|NA|NA E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine BNPNBKBE_00584 1046629.Ssal_00465 1.3e-142 512.3 Bacilli trpA 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPXA@1239,4HFQ8@91061,COG0159@1,COG0159@2 NA|NA|NA E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate BNPNBKBE_00586 435842.HMPREF0848_01207 4.2e-74 283.9 Bacteria copY Bacteria COG3682@1,COG3682@2 NA|NA|NA K negative regulation of transcription, DNA-templated BNPNBKBE_00587 435842.HMPREF0848_01206 0.0 1306.2 Bacilli copA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 1TP5S@1239,4HAI0@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase BNPNBKBE_00588 435842.HMPREF0848_01205 2.7e-31 140.6 Bacilli copZ GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0006811,GO:0006812,GO:0006873,GO:0006875,GO:0008150,GO:0009987,GO:0019725,GO:0030001,GO:0030003,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 2.7.7.77 ko:K03752,ko:K07213,ko:K08364 ko00790,ko01100,ko04978,map00790,map01100,map04978 R11581 ko00000,ko00001,ko01000,ko02000 1.A.72.1 Bacteria 1VK5F@1239,4HR1Z@91061,COG2608@1,COG2608@2 NA|NA|NA P Heavy metal-associated domain protein BNPNBKBE_00589 904306.HMPREF9192_0803 4.2e-192 677.2 Bacilli ddl 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TP2Y@1239,4H9KB@91061,COG1181@1,COG1181@2 NA|NA|NA F Belongs to the D-alanine--D-alanine ligase family BNPNBKBE_00591 1046629.Ssal_00473 6.6e-114 416.8 Bacilli papP ko:K02029 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TRU3@1239,4HGE1@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter (Permease BNPNBKBE_00592 1046629.Ssal_00474 1.9e-105 388.7 Bacilli ko:K02029 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TR7R@1239,4HGVA@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter (Permease BNPNBKBE_00593 1046629.Ssal_00475 7.6e-135 486.5 Bacilli glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,4HDK7@91061,COG1126@1,COG1126@2 NA|NA|NA E abc transporter atp-binding protein BNPNBKBE_00594 322159.STER_1539 9.7e-155 552.7 Bacilli cjaA ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TT11@1239,4HFBQ@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter substrate-binding protein BNPNBKBE_00598 904306.HMPREF9192_0808 3.6e-252 877.1 Bacilli murF 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1VT78@1239,4HACR@91061,COG0770@1,COG0770@2 NA|NA|NA M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein BNPNBKBE_00599 1046629.Ssal_00479 1.4e-116 425.6 Bacteria ywaF Bacteria COG5522@1,COG5522@2 NA|NA|NA S Integral membrane protein (intg_mem_TP0381) BNPNBKBE_00600 1046629.Ssal_00481 2.6e-299 1033.9 Bacilli prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02837,ko:K07133 ko00000,ko03012 Bacteria 1TPYT@1239,4HADS@91061,COG4108@1,COG4108@2 NA|NA|NA J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP BNPNBKBE_00601 1046629.Ssal_00485 2.4e-96 358.2 Bacilli thiT ko:K16789 ko00000,ko02000 2.A.88.3 Bacteria 1V6YE@1239,4HIJE@91061,COG3859@1,COG3859@2 NA|NA|NA S Thiamine transporter BNPNBKBE_00602 435842.HMPREF0848_01188 9.6e-62 242.7 Bacilli yjqA Bacteria 1V77G@1239,3172B@2,4HJ0W@91061,arCOG12631@1 NA|NA|NA S Bacterial PH domain BNPNBKBE_00603 1046629.Ssal_00487 7.6e-150 536.6 Bacilli corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1TPI8@1239,4HCQ6@91061,COG0598@1,COG0598@2 NA|NA|NA P CorA-like protein BNPNBKBE_00604 904306.HMPREF9192_0816 1.7e-253 881.7 Bacilli cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TPAP@1239,4HAB3@91061,COG0513@1,COG0513@2 NA|NA|NA JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity BNPNBKBE_00605 435842.HMPREF0848_01185 1e-41 175.6 Bacilli yazA ko:K07461 ko00000 Bacteria 1VEZF@1239,4HNHJ@91061,COG2827@1,COG2827@2 NA|NA|NA L endonuclease containing a URI domain BNPNBKBE_00606 1046629.Ssal_00490 1.8e-139 501.9 Bacilli yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 ko00000,ko01000,ko03016 Bacteria 1TQ25@1239,4HA8W@91061,COG4123@1,COG4123@2 NA|NA|NA L Methyltransferase BNPNBKBE_00607 435842.HMPREF0848_01183 9.3e-159 566.2 Bacilli nodB3 Bacteria 1TYRH@1239,4HHQN@91061,COG0726@1,COG0726@2 NA|NA|NA G deacetylase BNPNBKBE_00608 264199.stu1563 1.3e-142 512.3 Bacilli plsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1U8N2@1239,4HDQR@91061,COG0204@1,COG0204@2 NA|NA|NA I Acyltransferase BNPNBKBE_00609 1046629.Ssal_00493 2.2e-88 332.0 Bacilli comEA ko:K02237 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1VA3W@1239,4HKJ1@91061,COG1555@1,COG1555@2 NA|NA|NA L COG1555 DNA uptake protein and related DNA-binding proteins BNPNBKBE_00610 1046629.Ssal_00495 0.0 1395.2 Bacilli comEC ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1TS9U@1239,4H9M4@91061,COG0658@1,COG0658@2,COG2333@1,COG2333@2 NA|NA|NA S Competence protein ComEC BNPNBKBE_00611 1046629.Ssal_00497 5.1e-229 800.0 Bacilli murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 iYO844.BSU37100 Bacteria 1TPAU@1239,4H9KI@91061,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine BNPNBKBE_00612 1046629.Ssal_00498 5.3e-98 363.6 Bacilli XK27_07830 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 1V576@1239,4HH6U@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase GNAT Family BNPNBKBE_00613 1046629.Ssal_00499 2.5e-231 807.7 Bacilli ytoI Bacteria 1TPU6@1239,4HB62@91061,COG4109@1,COG4109@2 NA|NA|NA K transcriptional regulator containing CBS domains BNPNBKBE_00614 1046629.Ssal_00500 1.1e-166 592.4 Bacilli map GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 1TQC1@1239,4H9S9@91061,COG0024@1,COG0024@2 NA|NA|NA E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed BNPNBKBE_00615 1046629.Ssal_00501 8.4e-160 569.7 Bacilli rbn ko:K07058 ko00000 Bacteria 1U7HM@1239,4H9MJ@91061,COG1295@1,COG1295@2 NA|NA|NA E Belongs to the UPF0761 family BNPNBKBE_00616 1046629.Ssal_00502 1.1e-84 319.3 Bacilli ccl GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1V22G@1239,4HGG2@91061,COG4708@1,COG4708@2 NA|NA|NA S cog cog4708 BNPNBKBE_00617 904306.HMPREF9192_0832 0.0 1221.1 Bacilli ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1TPQ3@1239,4HA1D@91061,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA BNPNBKBE_00618 1046629.Ssal_00504 2.4e-184 651.4 Bacilli yegS GO:0001727,GO:0003674,GO:0003824,GO:0004143,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0030258,GO:0044237,GO:0044238,GO:0044255,GO:0046834,GO:0071704 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 R02240 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TQAU@1239,4H9WD@91061,COG1597@1,COG1597@2 NA|NA|NA I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase BNPNBKBE_00620 1046629.Ssal_00505 3.8e-171 607.4 Bacteria yfjR GO:0008150,GO:0043900,GO:0050789,GO:0050794,GO:0065007,GO:1900190 Bacteria COG2378@1,COG2378@2 NA|NA|NA K regulation of single-species biofilm formation BNPNBKBE_00622 1046629.Ssal_00507 5.4e-70 270.4 Bacilli Bacteria 1V99E@1239,4HXAN@91061,COG4708@1,COG4708@2 NA|NA|NA S QueT transporter BNPNBKBE_00623 435842.HMPREF0848_01166 3.4e-157 560.8 Bacilli xth GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPFB@1239,4HAIU@91061,COG0708@1,COG0708@2 NA|NA|NA L exodeoxyribonuclease III BNPNBKBE_00625 1095727.HMPREF1117_1254 2.9e-17 95.9 Bacilli yjdB Bacteria 1VFT3@1239,2DMBI@1,32H42@2,4HK1A@91061 NA|NA|NA S Domain of unknown function (DUF4767) BNPNBKBE_00626 904306.HMPREF9192_0841 2.1e-165 588.2 Bacilli tehB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0010035,GO:0016740,GO:0016741,GO:0032259,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046690,GO:0050896 2.1.1.265 ko:K03647,ko:K16868 ko00000,ko01000 Bacteria 1TSZK@1239,4HJT1@91061,COG0500@1,COG0500@2,COG3615@1,COG3615@2 NA|NA|NA PQ tellurite resistance protein tehb BNPNBKBE_00628 1046629.Ssal_00513 8.3e-93 346.3 Bacteria Bacteria COG5549@1,COG5549@2 NA|NA|NA O protein import BNPNBKBE_00630 1123309.AQYB01000022_gene40 1.9e-07 60.1 Bacilli Bacteria 1VNP3@1239,2ED1A@1,336Y8@2,4HRCX@91061 NA|NA|NA BNPNBKBE_00635 1046629.Ssal_02107 0.0 2819.6 Bacilli polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K02342,ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPAG@1239,4H9RF@91061,COG2176@1,COG2176@2 NA|NA|NA L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity BNPNBKBE_00636 1046629.Ssal_02106 1.9e-236 824.7 Bacilli pepS ko:K19689 ko00000,ko01000,ko01002 Bacteria 1TP65@1239,4H9W8@91061,COG2309@1,COG2309@2 NA|NA|NA E COG2309 Leucyl aminopeptidase (aminopeptidase T) BNPNBKBE_00637 904306.HMPREF9192_0535 1.2e-35 155.2 Bacteria XK27_02060 Bacteria COG2261@1,COG2261@2 NA|NA|NA S Transglycosylase associated protein BNPNBKBE_00638 1046629.Ssal_02104 4.8e-70 270.4 Bacilli badR ko:K15973 ko00000,ko03000 Bacteria 1VB3Q@1239,4HP7J@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator, marr family BNPNBKBE_00639 904306.HMPREF9192_0533 1.4e-93 349.0 Firmicutes ko:K19784 ko00000 Bacteria 1VAI8@1239,COG0431@1,COG0431@2 NA|NA|NA S reductase BNPNBKBE_00641 1046629.Ssal_02102 3.5e-288 996.9 Bacilli ahpF ko:K03387 ko00000,ko01000 Bacteria 1TPYN@1239,4H9W1@91061,COG3634@1,COG3634@2 NA|NA|NA O alkyl hydroperoxide reductase BNPNBKBE_00642 1046629.Ssal_02101 4.2e-106 390.6 Bacilli ahpC GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748 1.11.1.15 ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Bacteria 1TQU7@1239,4HA2M@91061,COG0450@1,COG0450@2 NA|NA|NA O alkyl hydroperoxide reductase BNPNBKBE_00643 1046629.Ssal_02100 7.4e-138 496.5 Bacilli rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPNA@1239,4H9N5@91061,COG0052@1,COG0052@2 NA|NA|NA J Belongs to the universal ribosomal protein uS2 family BNPNBKBE_00644 1046629.Ssal_02098 1e-182 646.0 Bacilli tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 ko:K02357 ko00000,ko03012,ko03029 Bacteria 1TPFJ@1239,4HBDV@91061,COG0264@1,COG0264@2 NA|NA|NA J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome BNPNBKBE_00645 435842.HMPREF0848_01885 1.6e-82 312.0 Bacilli Bacteria 1V3UW@1239,4HPN6@91061,COG2426@1,COG2426@2 NA|NA|NA S Putative small multi-drug export protein BNPNBKBE_00646 1046629.Ssal_02095 3.1e-75 287.7 Bacilli ctsR GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 ko:K03708 ko00000,ko03000 Bacteria 1VAXT@1239,4HIFT@91061,COG4463@1,COG4463@2 NA|NA|NA K Belongs to the CtsR family BNPNBKBE_00647 904306.HMPREF9192_0525 0.0 1540.8 Bacilli clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 1TPMU@1239,4HACY@91061,COG0542@1,COG0542@2 NA|NA|NA O Belongs to the ClpA ClpB family BNPNBKBE_00648 1046629.Ssal_02093 1.2e-230 805.4 Bacilli dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1TQN0@1239,4HBD4@91061,COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family BNPNBKBE_00649 1046629.Ssal_02092 6.9e-226 789.6 Bacilli dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1TQN0@1239,4HBD4@91061,COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family BNPNBKBE_00650 1046629.Ssal_02091 0.0 1354.7 Bacilli pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 1TQDW@1239,4H9Z3@91061,COG1185@1,COG1185@2 NA|NA|NA J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction BNPNBKBE_00651 1046629.Ssal_02090 4.7e-140 503.8 Bacilli Bacteria 1VY65@1239,2F67I@1,33YRI@2,4HXHY@91061 NA|NA|NA S SseB protein N-terminal domain BNPNBKBE_00652 435842.HMPREF0848_01892 3.3e-112 411.0 Bacilli cysE 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR42@1239,4HAKS@91061,COG1045@1,COG1045@2 NA|NA|NA E serine acetyltransferase BNPNBKBE_00654 1046629.Ssal_02087 3.1e-256 890.6 Bacilli cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16,6.3.1.13 ko:K01883,ko:K15526 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECUMN_1333.ECUMN_0566,iJN746.PP_2905 Bacteria 1TP9D@1239,4HA6D@91061,COG0215@1,COG0215@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family BNPNBKBE_00655 1046629.Ssal_02085 3.6e-67 260.8 Bacilli mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 ko:K11145 ko00000,ko01000,ko03009 Bacteria 1VA5V@1239,4HIM3@91061,COG1939@1,COG1939@2 NA|NA|NA J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) BNPNBKBE_00657 1046629.Ssal_02082 1.1e-133 482.6 Bacilli trmH GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218,ko:K03437,ko:K12952 ko00000,ko01000,ko03009,ko03016 3.A.3.23 Bacteria 1TP9G@1239,4HBBI@91061,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family BNPNBKBE_00658 1046629.Ssal_02081 6e-91 340.1 Bacilli yacP ko:K06962 ko00000 Bacteria 1V9XR@1239,4HFW4@91061,COG3688@1,COG3688@2 NA|NA|NA S RNA-binding protein containing a PIN domain BNPNBKBE_00659 1046629.Ssal_02080 5.4e-153 547.0 Bacilli degV Bacteria 1TQDI@1239,4HAYQ@91061,COG1307@1,COG1307@2 NA|NA|NA S DegV family BNPNBKBE_00661 1046629.Ssal_02078 5.1e-22 109.8 Bacilli ko:K07729 ko00000,ko03000 Bacteria 1VERT@1239,4HNID@91061,COG1476@1,COG1476@2 NA|NA|NA K Transcriptional BNPNBKBE_00662 1046629.Ssal_02077 2e-79 301.6 Bacilli rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3HX@1239,4HG0I@91061,COG0102@1,COG0102@2 NA|NA|NA J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly BNPNBKBE_00663 435842.HMPREF0848_01903 1.2e-64 252.3 Bacilli rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3MQ@1239,4HH3B@91061,COG0103@1,COG0103@2 NA|NA|NA J Belongs to the universal ribosomal protein uS9 family BNPNBKBE_00664 862967.SIR_1575 1.2e-222 778.9 Streptococcus anginosus group int2 Bacteria 1TRCD@1239,42DYV@671232,4HDUS@91061,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase family BNPNBKBE_00665 759913.SDSE_0290 1.6e-39 168.3 Streptococcus dysgalactiae group Bacteria 1MA56@119603,1TVYU@1239,2DITM@1,3043S@2,4I4M0@91061 NA|NA|NA L Helix-turn-helix domain BNPNBKBE_00666 759913.SDSE_0291 4.8e-193 680.2 Bacilli ko:K07467 ko00000 Bacteria 1V0X4@1239,4HF5X@91061,COG2946@1,COG2946@2 NA|NA|NA L Replication initiation factor BNPNBKBE_00667 585204.SMSK597_1428 1e-35 156.4 Streptococcus mitis Bacteria 1U4K6@1239,2DKDH@1,2TQ0T@28037,3097S@2,4IEBY@91061 NA|NA|NA BNPNBKBE_00669 1123303.AQVD01000005_gene1271 3.9e-43 181.8 Firmicutes Bacteria 1TRBW@1239,COG1476@1,COG1476@2 NA|NA|NA K DNA-binding helix-turn-helix protein BNPNBKBE_00670 999425.HMPREF9186_01001 8.2e-63 246.1 Bacilli rmeD ko:K13640 ko00000,ko03000 Bacteria 1VB69@1239,4HKUK@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance BNPNBKBE_00671 888833.HMPREF9421_0321 1.4e-136 492.3 Bacilli ko:K07124 ko00000 Bacteria 1TR8Z@1239,4H9ZH@91061,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family BNPNBKBE_00672 435842.HMPREF0848_01907 8.9e-110 402.9 Bacilli fic ko:K04095 ko00000,ko03036 Bacteria 1TPUZ@1239,4HIQT@91061,COG2184@1,COG2184@2 NA|NA|NA D Fic/DOC family BNPNBKBE_00673 435842.HMPREF0848_01908 4.5e-28 129.8 Firmicutes Bacteria 1VPN1@1239,2ETKC@1,33M40@2 NA|NA|NA BNPNBKBE_00674 862967.SIR_1563 2.9e-82 311.2 Streptococcus anginosus group Bacteria 1V6MD@1239,2BH95@1,32BAK@2,42DVS@671232,4I42D@91061 NA|NA|NA BNPNBKBE_00675 246201.SM12261_1278 1.3e-17 96.7 Streptococcus mitis Bacteria 1U4C6@1239,2DKB4@1,2TPFS@28037,3092R@2,4IE3Z@91061 NA|NA|NA BNPNBKBE_00676 1046629.Ssal_02065 1.5e-29 134.8 Bacilli ko:K07729 ko00000,ko03000 Bacteria 1VEGF@1239,4IPKE@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix domain BNPNBKBE_00678 435842.HMPREF0848_01916 8.6e-148 529.6 Bacilli srtB 3.4.22.70 ko:K08600 ko00000,ko01000,ko01002,ko01011 Bacteria 1V2FT@1239,4IQ4U@91061,COG4509@1,COG4509@2 NA|NA|NA S Sortase family BNPNBKBE_00679 1046629.Ssal_02062 9.7e-233 812.4 Bacilli capA ko:K07282 ko00000 Bacteria 1UZW4@1239,4HBC3@91061,COG2843@1,COG2843@2 NA|NA|NA M Bacterial capsule synthesis protein BNPNBKBE_00680 1046629.Ssal_02061 2.3e-38 164.5 Bacilli gcvR ko:K07166 ko00000 Bacteria 1VENW@1239,4HNJ4@91061,COG3830@1,COG3830@2 NA|NA|NA T UPF0237 protein BNPNBKBE_00681 435842.HMPREF0848_01919 2.1e-241 841.3 Bacilli XK27_08635 ko:K09157 ko00000 Bacteria 1TQG8@1239,4HBTU@91061,COG2848@1,COG2848@2 NA|NA|NA S UPF0210 protein BNPNBKBE_00682 904306.HMPREF9192_0488 4.3e-132 477.2 Bacilli ais Bacteria 1VDCB@1239,4HJ9X@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase BNPNBKBE_00683 1046629.Ssal_02058 2.6e-138 498.0 Bacilli vanY 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Bacteria 1V1F7@1239,4HBR1@91061,COG1876@1,COG1876@2 NA|NA|NA M D-alanyl-D-alanine carboxypeptidase BNPNBKBE_00684 1046629.Ssal_02057 3.6e-100 370.9 Bacilli acmA 3.2.1.17,3.4.17.14,3.5.1.28 ko:K01185,ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 M00651,M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 Bacteria 1V7JY@1239,4HIY4@91061,COG1705@1,COG1705@2 NA|NA|NA NU Muramidase (Flagellum-specific) BNPNBKBE_00685 904306.HMPREF9192_0485 3.7e-185 654.1 Bacilli hrcA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K03705 ko00000,ko03000 Bacteria 1TQP7@1239,4HAX5@91061,COG1420@1,COG1420@2 NA|NA|NA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons BNPNBKBE_00686 1046629.Ssal_02055 9.1e-63 246.5 Bacilli grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 ko:K03687 ko00000,ko03029,ko03110 Bacteria 1V6G2@1239,4HIRK@91061,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BNPNBKBE_00687 904306.HMPREF9192_0483 1.4e-304 1051.6 Bacilli dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 1TP1J@1239,4HA9S@91061,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein BNPNBKBE_00688 1046629.Ssal_02052 8e-189 666.4 Bacilli dnaJ ko:K03686 ko00000,ko03029,ko03110 Bacteria 1TP00@1239,4H9KA@91061,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins BNPNBKBE_00689 1046629.Ssal_02051 3.8e-139 500.7 Bacilli truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 1TQUY@1239,4HCFI@91061,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs BNPNBKBE_00690 904306.HMPREF9192_0479 3.8e-134 484.2 Bacilli thiD 2.7.1.35,2.7.1.49,2.7.4.7 ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 M00127 R00174,R01909,R02493,R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ4A@1239,4H9PP@91061,COG0351@1,COG0351@2 NA|NA|NA H phosphomethylpyrimidine kinase BNPNBKBE_00691 1046629.Ssal_02049 1.1e-78 299.3 Bacilli hmpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1VBBN@1239,4HNM0@91061,COG4720@1,COG4720@2 NA|NA|NA S cog cog4720 BNPNBKBE_00692 561229.Dd1591_1473 8.4e-131 473.4 Dickeya Bacteria 1MU8I@1224,1RNU7@1236,2JEYP@204037,COG4227@1,COG4227@2 NA|NA|NA L Domain of unknown function (DUF1738) BNPNBKBE_00693 176090.SSIN_0787 9e-190 669.8 Firmicutes Bacteria 1TQK6@1239,28ISM@1,2Z8RR@2 NA|NA|NA BNPNBKBE_00694 322159.STER_1329 3e-97 361.7 Bacteria Bacteria 2A1SH@1,30Q17@2 NA|NA|NA S Abortive infection C-terminus BNPNBKBE_00695 322159.STER_1330 0.0 2395.9 Bacilli Bacteria 1U2DR@1239,4HBX2@91061,COG1061@1,COG1061@2 NA|NA|NA L DEAD-like helicases superfamily BNPNBKBE_00696 322159.STER_1331 9.8e-118 429.5 Bacilli 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1V86D@1239,4HJKH@91061,COG0286@1,COG0286@2 NA|NA|NA V site-specific DNA-methyltransferase (adenine-specific) activity BNPNBKBE_00697 1227352.C173_08521 1e-23 116.3 Paenibacillaceae ko:K07282 ko00000 Bacteria 1V0MA@1239,26UAG@186822,4HFA1@91061,COG2843@1,COG2843@2 NA|NA|NA M Bacterial capsule synthesis protein PGA_cap BNPNBKBE_00698 1046629.Ssal_00769 1.9e-226 791.6 Bacilli vncS 2.7.13.3 ko:K10819,ko:K18986 ko02020,map02020 M00719 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQZD@1239,4HDFP@91061,COG0642@1,COG0642@2 NA|NA|NA T Histidine kinase BNPNBKBE_00699 999425.HMPREF9186_00549 4.4e-115 420.6 Bacilli Bacteria 1TT7R@1239,4HG6F@91061,COG0745@1,COG0745@2 NA|NA|NA K Response regulator receiver domain protein BNPNBKBE_00700 904306.HMPREF9192_1059 2.6e-234 817.8 Bacilli vex3 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPSE@1239,4HDMR@91061,COG0577@1,COG0577@2 NA|NA|NA V Efflux ABC transporter, permease protein BNPNBKBE_00701 904306.HMPREF9192_1058 2.3e-105 388.3 Bacilli vex2 ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TP5M@1239,4HBJW@91061,COG1136@1,COG1136@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_00702 904306.HMPREF9192_1057 5.8e-180 637.1 Bacilli vex1 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TT8B@1239,4HFDY@91061,COG0577@1,COG0577@2 NA|NA|NA V Efflux ABC transporter, permease protein BNPNBKBE_00703 1046629.Ssal_00764 2.5e-283 980.7 Bacilli XK27_07020 Bacteria 1TQYE@1239,4HDNX@91061,COG4868@1,COG4868@2 NA|NA|NA S Belongs to the UPF0371 family BNPNBKBE_00705 1046629.Ssal_00761 4.3e-200 703.7 Bacilli gldA 1.1.1.6 ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 R01034,R10715,R10717 RC00029,RC00117,RC00670 ko00000,ko00001,ko01000 Bacteria 1TQFU@1239,4HC8K@91061,COG0371@1,COG0371@2 NA|NA|NA C glycerol dehydrogenase BNPNBKBE_00706 1046629.Ssal_00760 2.4e-181 641.3 Bacilli XK27_10475 Bacteria 1TPT5@1239,4HAPJ@91061,COG0673@1,COG0673@2 NA|NA|NA S oxidoreductase BNPNBKBE_00707 1046629.Ssal_00759 1.4e-57 228.8 Firmicutes dhaM GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324 2.7.1.121 ko:K05881 ko00561,map00561 R01012 RC00015,RC00017 ko00000,ko00001,ko01000,ko02000 Bacteria 1VF32@1239,COG3412@1,COG3412@2 NA|NA|NA S dihydroxyacetone kinase, phosphotransfer subunit BNPNBKBE_00708 1046629.Ssal_00758 2.6e-95 354.8 Bacilli dhaL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0046872,GO:0047324,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.1.121 ko:K05879 ko00561,ko01100,map00561,map01100 R01012 RC00015,RC00017 ko00000,ko00001,ko01000 Bacteria 1V4FH@1239,4HGZY@91061,COG1461@1,COG1461@2 NA|NA|NA S Dihydroxyacetone kinase BNPNBKBE_00709 1046629.Ssal_00757 1e-176 625.9 Bacilli dhaK GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019637,GO:0019751,GO:0033554,GO:0034308,GO:0042180,GO:0042182,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0047324,GO:0050896,GO:0051716,GO:0061610,GO:0071704,GO:1901135,GO:1901575,GO:1901615 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 ko:K00863,ko:K05878,ko:K05879 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 M00344 R01011,R01012,R01059 RC00002,RC00015,RC00017 ko00000,ko00001,ko00002,ko01000 iEcHS_1320.EcHS_A1304,iUMNK88_1353.UMNK88_1515,iYL1228.KPN_03495 Bacteria 1TP92@1239,4H9VS@91061,COG2376@1,COG2376@2 NA|NA|NA G Dihydroxyacetone kinase BNPNBKBE_00710 1046629.Ssal_00756 2.8e-227 794.3 Firmicutes thrE Bacteria 1TSE8@1239,COG2966@1,COG2966@2,COG3610@1,COG3610@2 NA|NA|NA K Psort location CytoplasmicMembrane, score BNPNBKBE_00711 1046629.Ssal_00755 0.0 2023.4 Firmicutes Bacteria 1V0PX@1239,COG5263@1,COG5263@2 NA|NA|NA M Putative cell wall binding repeat BNPNBKBE_00712 999425.HMPREF9186_00431 7.8e-125 453.4 Bacilli Bacteria 1VDTG@1239,4HKC1@91061,COG0639@1,COG0639@2 NA|NA|NA T Ser Thr phosphatase family protein BNPNBKBE_00713 927666.SOR_0713 2.1e-33 148.3 Bacilli Bacteria 1U54E@1239,2DKHV@1,309HT@2,4I1BW@91061 NA|NA|NA S Immunity protein 41 BNPNBKBE_00714 1046629.Ssal_00750 0.0 1294.3 Bacilli pepO 3.4.24.71 ko:K01415,ko:K07386 ko00000,ko01000,ko01002,ko04147 Bacteria 1TQTA@1239,4HDSF@91061,COG3590@1,COG3590@2 NA|NA|NA O Peptidase family M13 BNPNBKBE_00715 1069533.Sinf_1729 9e-08 63.2 Bacilli Bacteria 1VP2X@1239,2EGBF@1,33A3A@2,4HS3U@91061 NA|NA|NA S Enterocin A Immunity BNPNBKBE_00716 365659.smi_1095 2.5e-197 695.3 Bacilli Bacteria 1UQNK@1239,4HNVT@91061,COG4928@1,COG4928@2 NA|NA|NA S KAP family P-loop domain BNPNBKBE_00717 1046629.Ssal_00742 0.0 2704.9 Bacilli GO:0005575,GO:0005576 2.4.1.5 ko:K00689,ko:K20276 ko00500,ko02020,ko02024,map00500,map02020,map02024 R02120,R06066 RC00028 ko00000,ko00001,ko01000 GH13 Bacteria 1VQXK@1239,4HEIA@91061,COG0366@1,COG0366@2,COG5263@1,COG5263@2 NA|NA|NA M KxYKxGKxW signal domain protein BNPNBKBE_00719 888808.HMPREF9380_0205 4.4e-66 258.5 Streptococcus sanguinis Bacteria 1TVSW@1239,1WS7J@1305,2DJYQ@1,307W3@2,4IKSM@91061 NA|NA|NA BNPNBKBE_00720 1046629.Ssal_00740 1.7e-258 898.7 Bacteria Bacteria COG5263@1,COG5263@2 NA|NA|NA S dextransucrase activity BNPNBKBE_00721 1046629.Ssal_00738 0.0 2320.4 Bacilli GO:0005575,GO:0005576 2.4.1.5 ko:K00689,ko:K20276 ko00500,ko02020,ko02024,map00500,map02020,map02024 R02120,R06066 RC00028 ko00000,ko00001,ko01000 GH13 Bacteria 1VQXK@1239,4HEIA@91061,COG0366@1,COG0366@2,COG5263@1,COG5263@2 NA|NA|NA M KxYKxGKxW signal domain protein BNPNBKBE_00722 1046629.Ssal_00734 2.3e-13 81.3 Firmicutes Bacteria 1V0PX@1239,COG5263@1,COG5263@2 NA|NA|NA M Putative cell wall binding repeat BNPNBKBE_00724 562981.HMPREF0428_01670 5.5e-31 139.8 Bacilli Bacteria 1VENK@1239,4HNKV@91061,COG2261@1,COG2261@2 NA|NA|NA S Membrane BNPNBKBE_00725 638301.HMPREF0444_0929 2.9e-09 67.4 Bacilli Bacteria 1VGX4@1239,4HY48@91061,COG3237@1,COG3237@2 NA|NA|NA S CsbD-like BNPNBKBE_00726 1123300.AUIN01000017_gene643 4.7e-172 610.9 Bacilli pdhD 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TP1W@1239,4H9Z5@91061,COG1249@1,COG1249@2 NA|NA|NA C Dehydrogenase BNPNBKBE_00727 888816.HMPREF9389_1676 3.6e-167 594.3 Streptococcus sanguinis acoA ko:K21416 ko00000,ko01000 Bacteria 1TQDG@1239,1WQRY@1305,4HBEA@91061,COG1071@1,COG1071@2 NA|NA|NA C Acetoin dehydrogenase E1 component subunit alpha BNPNBKBE_00728 388919.SSA_1139 1.3e-174 619.0 Streptococcus sanguinis acoB ko:K21417 ko00000,ko01000 Bacteria 1TP3J@1239,1WR3E@1305,4HAP6@91061,COG0022@1,COG0022@2 NA|NA|NA C dehydrogenase E1 component BNPNBKBE_00729 699248.SRA_06236 2.5e-143 515.4 Bacilli acoC 2.3.1.12,2.3.1.61 ko:K00627,ko:K00658 ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032,M00307 R00209,R02569,R02570,R02571,R08549 RC00004,RC02727,RC02742,RC02833,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TR5N@1239,4HDFT@91061,COG0508@1,COG0508@2 NA|NA|NA C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex BNPNBKBE_00730 1316408.HSISM1_1770 7.6e-82 310.1 Bacilli Bacteria 1UI83@1239,4HHCN@91061,COG0500@1,COG0500@2 NA|NA|NA Q Methyltransferase domain BNPNBKBE_00731 1123300.AUIN01000009_gene228 5.8e-74 283.9 Bacilli ko:K09017 ko00000,ko03000 Bacteria 1VCGN@1239,4HMEM@91061,COG1309@1,COG1309@2 NA|NA|NA K TetR family transcriptional regulator BNPNBKBE_00732 1046629.Ssal_01462 1.8e-45 188.3 Firmicutes Bacteria 1VAQK@1239,2CUT8@1,32SW2@2 NA|NA|NA BNPNBKBE_00733 435842.HMPREF0848_00314 5.7e-127 460.3 Bacteria Bacteria COG1266@1,COG1266@2 NA|NA|NA V CAAX protease self-immunity BNPNBKBE_00734 585203.SMSK564_1364 5.8e-10 69.7 Streptococcus mitis Bacteria 1U4XP@1239,2DKGP@1,2TQDW@28037,309EM@2,4IEP2@91061 NA|NA|NA BNPNBKBE_00735 1005705.HMPREF9967_0252 2.6e-20 105.1 Streptococcus infantis Bacteria 1TWG1@1239,2DIXF@1,304BM@2,43G59@68892,4I59C@91061 NA|NA|NA M Bacterial lipoprotein BNPNBKBE_00736 435842.HMPREF0848_00317 4.1e-60 237.3 Bacilli ko:K13281 ko00000,ko01000 Bacteria 1VGGK@1239,4HP7S@91061,COG3272@1,COG3272@2 NA|NA|NA S Protein of unknown function (DUF1722) BNPNBKBE_00737 1046629.Ssal_01457 2.8e-63 247.7 Bacilli yqeB Bacteria 1V717@1239,2AK1X@1,31ARI@2,4HIQ9@91061 NA|NA|NA S Pyrimidine dimer DNA glycosylase BNPNBKBE_00739 1046629.Ssal_01455 1.6e-50 205.3 Firmicutes Bacteria 1VZAT@1239,2FBVV@1,3440F@2 NA|NA|NA BNPNBKBE_00740 1046629.Ssal_01454 8.9e-94 349.7 Bacilli Bacteria 1VBYM@1239,4HM2K@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity BNPNBKBE_00741 1046629.Ssal_01453 2.8e-20 103.6 Bacilli estA Bacteria 1V1CQ@1239,4HGVZ@91061,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase BNPNBKBE_00742 1046629.Ssal_01453 2.3e-54 218.0 Bacilli estA Bacteria 1V1CQ@1239,4HGVZ@91061,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase BNPNBKBE_00743 1046629.Ssal_01451 9.9e-101 372.9 Firmicutes Bacteria 1VYAW@1239,2F636@1,33YMH@2 NA|NA|NA BNPNBKBE_00744 1046629.Ssal_01450 4.3e-276 956.8 Bacilli sulP GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015810,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 ko:K03321 ko00000,ko02000 2.A.53.3 iSbBS512_1146.SbBS512_E1370 Bacteria 1TPI4@1239,4H9V4@91061,COG0659@1,COG0659@2 NA|NA|NA P Sulfate permease and related transporters (MFS superfamily) BNPNBKBE_00745 904306.HMPREF9192_1125 9.9e-149 532.7 Bacilli ycgQ ko:K08986 ko00000 Bacteria 1V3EX@1239,4HGMG@91061,COG3689@1,COG3689@2 NA|NA|NA S TIGR03943 family BNPNBKBE_00746 1046629.Ssal_01448 9.3e-156 556.2 Bacilli XK27_03015 ko:K07089 ko00000 Bacteria 1TQHK@1239,4HB25@91061,COG0701@1,COG0701@2 NA|NA|NA S permease BNPNBKBE_00748 904306.HMPREF9192_1128 0.0 1325.1 Bacilli yhgF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 ko:K06959 ko00000 Bacteria 1TPFE@1239,4HAGY@91061,COG2183@1,COG2183@2 NA|NA|NA K Transcriptional accessory protein BNPNBKBE_00749 1046629.Ssal_01444 2.2e-41 174.5 Bacilli pspC ko:K03973 ko00000,ko02048,ko03000 Bacteria 1VF0M@1239,4IRAN@91061,COG1983@1,COG1983@2 NA|NA|NA KT PspC domain BNPNBKBE_00750 1046629.Ssal_01443 1.9e-167 595.1 Bacilli hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06023 ko00000,ko01000 Bacteria 1TP5Z@1239,4HAXR@91061,COG1493@1,COG1493@2 NA|NA|NA F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion BNPNBKBE_00751 1046629.Ssal_01442 9.9e-146 522.7 Bacilli lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 ko:K03438,ko:K13292 ko00000,ko01000,ko03009 Bacteria 1TPAK@1239,4HAT0@91061,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins BNPNBKBE_00752 904306.HMPREF9192_1133 3.7e-08 64.7 Bacilli WQ51_05790 Bacteria 1VAXN@1239,4HM93@91061,COG4768@1,COG4768@2 NA|NA|NA S protein containing a divergent version of the methyl-accepting chemotaxis-like domain BNPNBKBE_00753 1046629.Ssal_01439 3e-67 261.2 Bacilli ytxH Bacteria 1VFY7@1239,4HNWV@91061,COG4980@1,COG4980@2 NA|NA|NA S General stress protein BNPNBKBE_00755 1046629.Ssal_01437 1.5e-177 628.6 Bacilli yegQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Bacteria 1TQIZ@1239,4HA2T@91061,COG0826@1,COG0826@2 NA|NA|NA O Peptidase U32 BNPNBKBE_00756 904306.HMPREF9192_1140 8.3e-251 872.5 Bacilli yegQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Bacteria 1TPRE@1239,4HBEG@91061,COG0826@1,COG0826@2 NA|NA|NA O Peptidase U32 BNPNBKBE_00757 1046629.Ssal_01434 1.1e-87 329.3 Bacilli bioY ko:K03523 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 Bacteria 1VA1G@1239,4HNE8@91061,COG1268@1,COG1268@2 NA|NA|NA S biotin synthase BNPNBKBE_00759 264199.stu0676 1.1e-33 148.7 Bacilli XK27_12190 Bacteria 1VEFE@1239,4HNSP@91061,COG4443@1,COG4443@2 NA|NA|NA S protein conserved in bacteria BNPNBKBE_00760 1046629.Ssal_01431 4.8e-233 813.5 Bacilli mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 1TPT1@1239,4HAEA@91061,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system BNPNBKBE_00761 888821.HMPREF9394_0792 6.7e-13 80.1 Streptococcus sanguinis Bacteria 1UA84@1239,1WRWU@1305,29RMD@1,30CQM@2,4IKJF@91061 NA|NA|NA BNPNBKBE_00762 888049.HMPREF8578_1747 1.5e-15 89.7 Streptococcus oralis Bacteria 1TX21@1239,1WQ4M@1303,2ADJV@1,313AA@2,4I5XT@91061 NA|NA|NA BNPNBKBE_00763 435842.HMPREF0848_00346 1.4e-286 991.5 Bacilli lysS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP2P@1239,4H9X4@91061,COG1190@1,COG1190@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family BNPNBKBE_00764 1046629.Ssal_01428 2.8e-137 495.4 Bacteria Bacteria COG1388@1,COG1388@2 NA|NA|NA M LysM domain BNPNBKBE_00765 904293.HMPREF9176_0571 8.4e-23 113.6 Bacilli Bacteria 1VVCA@1239,2BXK6@1,33WGZ@2,4HWEI@91061 NA|NA|NA BNPNBKBE_00766 1046629.Ssal_01424 5.2e-175 620.2 Bacilli ko:K07025 ko00000 Bacteria 1V5P7@1239,4HHGY@91061,COG1011@1,COG1011@2 NA|NA|NA S hydrolase BNPNBKBE_00768 904306.HMPREF9192_1153 1.6e-114 418.7 Bacilli pgm6 5.4.2.11,5.4.2.12 ko:K01834,ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1V7EZ@1239,4HJCK@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase BNPNBKBE_00769 1046629.Ssal_01422 1.1e-80 305.8 Bacilli ybaK ko:K03976 ko00000,ko01000,ko03016 Bacteria 1V6JF@1239,4HIH1@91061,COG2606@1,COG2606@2 NA|NA|NA S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily BNPNBKBE_00770 435842.HMPREF0848_00353 9.4e-140 503.1 Bacilli XK27_00880 3.5.1.28 ko:K01447,ko:K07273 R04112 RC00064,RC00141 ko00000,ko01000 Bacteria 1V2YH@1239,4HI8U@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolase, family 25 BNPNBKBE_00771 1123304.AQYA01000028_gene1720 6e-27 127.1 Bacteria Bacteria COG2461@1,COG2461@2 NA|NA|NA P Hemerythrin HHE cation binding domain protein BNPNBKBE_00772 1046629.Ssal_01419 9.9e-152 542.7 Bacilli 5.2.1.8 ko:K03768 ko00000,ko01000,ko03110 Bacteria 1UFDJ@1239,4HDIH@91061,COG0561@1,COG0561@2 NA|NA|NA G hydrolase BNPNBKBE_00773 1046629.Ssal_01418 7.9e-114 416.4 Bacilli 1.14.14.5 ko:K04091 ko00920,map00920 R07210,R10206 RC01779,RC02556 ko00000,ko00001,ko01000 Bacteria 1VJRB@1239,4ISN7@91061,COG2141@1,COG2141@2 NA|NA|NA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases BNPNBKBE_00774 904306.HMPREF9192_1160 9.6e-198 696.0 Bacilli MA20_36090 Bacteria 1VEWD@1239,4IQU0@91061,COG1073@1,COG1073@2 NA|NA|NA S Protein of unknown function (DUF2974) BNPNBKBE_00775 904306.HMPREF9192_1161 8.4e-134 483.0 Bacilli sdh 1.1.1.276,1.1.1.313,1.1.1.381 ko:K05886,ko:K15373,ko:K16066 ko00240,ko00260,ko00430,ko01100,map00240,map00260,map00430,map01100 R02600,R09289,R10851,R10852 RC00087,RC00525,RC03288 ko00000,ko00001,ko01000 Bacteria 1V08N@1239,4IPTJ@91061,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family BNPNBKBE_00776 435842.HMPREF0848_00358 4.4e-45 187.2 Bacilli Bacteria 1VBJ4@1239,4HQA2@91061,COG4679@1,COG4679@2 NA|NA|NA S Phage derived protein Gp49-like (DUF891) BNPNBKBE_00777 1046629.Ssal_01414 3.8e-45 187.2 Firmicutes Bacteria 1VD4K@1239,COG3620@1,COG3620@2 NA|NA|NA K Helix-turn-helix domain BNPNBKBE_00778 999425.HMPREF9186_01844 4.7e-41 173.7 Bacilli Bacteria 1VA3E@1239,4HKDQ@91061,COG1694@1,COG1694@2 NA|NA|NA S Nucleotide pyrophosphohydrolase BNPNBKBE_00779 1346.DQ08_04855 1.2e-188 666.4 Bacilli ko:K09384 ko00000 Bacteria 1TPQU@1239,4HBI0@91061,COG3410@1,COG3410@2 NA|NA|NA L Uncharacterized conserved protein (DUF2075) BNPNBKBE_00780 1046629.Ssal_01404 2e-134 485.3 Bacteria Bacteria COG5464@1,COG5464@2 NA|NA|NA S double-stranded DNA endodeoxyribonuclease activity BNPNBKBE_00781 1046629.Ssal_01135 0.0 1092.8 Bacilli lpdA 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TP1W@1239,4H9Z5@91061,COG1249@1,COG1249@2 NA|NA|NA C Dehydrogenase BNPNBKBE_00782 904306.HMPREF9192_1715 0.0 2023.1 Bacteria 3.5.1.28 ko:K01448,ko:K02395,ko:K21471 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036 Bacteria COG0860@1,COG0860@2,COG1705@1,COG1705@2,COG3757@1,COG3757@2,COG5263@1,COG5263@2 NA|NA|NA NU amidase activity BNPNBKBE_00783 435842.HMPREF0848_00646 0.0 1540.8 Firmicutes 3.5.1.28 ko:K01448,ko:K02172,ko:K02395 ko01501,ko01503,map01501,map01503 M00627,M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 Bacteria 1V5SF@1239,COG0860@1,COG0860@2,COG1705@1,COG1705@2 NA|NA|NA M N-Acetylmuramoyl-L-alanine amidase BNPNBKBE_00784 1046629.Ssal_01131 0.0 2368.2 Bacilli pulA 3.2.1.1,3.2.1.41 ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 R02108,R02111,R02112,R11262 ko00000,ko00001,ko01000 CBM48,GH13 Bacteria 1TP3M@1239,4HBP5@91061,COG1523@1,COG1523@2 NA|NA|NA G belongs to the glycosyl hydrolase 13 family BNPNBKBE_00785 1046629.Ssal_01125 4.9e-146 523.9 Bacilli ycdO GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0008150,GO:0015684,GO:0030001,GO:0051179,GO:0051234,GO:0070838,GO:0072511 ko:K07224,ko:K07243 ko00000,ko02000 2.A.108.1,2.A.108.2,2.A.108.2.3 Bacteria 1TS89@1239,4HB0W@91061,COG2822@1,COG2822@2 NA|NA|NA P periplasmic lipoprotein involved in iron transport BNPNBKBE_00786 904306.HMPREF9192_1720 1.1e-231 808.9 Bacilli ycdB ko:K16301 ko00000,ko01000,ko02000 2.A.108.2.3 Bacteria 1UY9Y@1239,4HACQ@91061,COG2837@1,COG2837@2 NA|NA|NA P peroxidase BNPNBKBE_00787 1046629.Ssal_01123 1.6e-286 991.5 Bacilli ywbL ko:K07243 ko00000,ko02000 2.A.108.1,2.A.108.2 Bacteria 1TQIA@1239,4HCJZ@91061,COG0672@1,COG0672@2 NA|NA|NA P COG0672 High-affinity Fe2 Pb2 permease BNPNBKBE_00788 435842.HMPREF0848_00652 1.9e-119 435.3 Bacilli tatC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 ko:K03118 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 1U7N7@1239,4HB1U@91061,COG0805@1,COG0805@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes BNPNBKBE_00789 1046629.Ssal_01121 1e-24 118.6 Firmicutes tatA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 1VGUJ@1239,COG1826@1,COG1826@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system BNPNBKBE_00790 1046629.Ssal_01120 4.7e-213 746.9 Bacilli msmX ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko02000 3.A.1.1 Bacteria 1TP2M@1239,4HAMQ@91061,COG3842@1,COG3842@2 NA|NA|NA P Belongs to the ABC transporter superfamily BNPNBKBE_00791 1046629.Ssal_01119 2.2e-151 541.6 Bacilli malG ko:K15772 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 Bacteria 1TRB7@1239,4HC5K@91061,COG3833@1,COG3833@2 NA|NA|NA P ABC transporter (Permease BNPNBKBE_00792 904306.HMPREF9192_1726 5.7e-250 869.8 Bacilli malF ko:K02025,ko:K02026,ko:K15771 ko02010,map02010 M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2 Bacteria 1TR2A@1239,4HB8H@91061,COG1175@1,COG1175@2 NA|NA|NA P ABC transporter (Permease BNPNBKBE_00793 1046629.Ssal_01117 9.6e-228 795.8 Bacilli malX ko:K02027,ko:K15770 ko02010,map02010 M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2 Bacteria 1TPU9@1239,4H9TU@91061,COG2182@1,COG2182@2 NA|NA|NA G ABC transporter BNPNBKBE_00794 1046629.Ssal_01116 1.7e-171 608.6 Bacilli malR ko:K02529 ko00000,ko03000 Bacteria 1TPZM@1239,4H9ZT@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator BNPNBKBE_00795 1046629.Ssal_01115 1.2e-298 1031.6 Bacilli malQ 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 R05196 RC00049 ko00000,ko00001,ko01000 GH77 Bacteria 1W5VQ@1239,4HCHB@91061,COG1640@1,COG1640@2 NA|NA|NA G 4-alpha-glucanotransferase BNPNBKBE_00796 1046629.Ssal_01114 0.0 1484.5 Bacilli glgP 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 R02111 ko00000,ko00001,ko01000 GT35 Bacteria 1TQAJ@1239,4H9XI@91061,COG0058@1,COG0058@2 NA|NA|NA G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties BNPNBKBE_00797 888821.HMPREF9394_1234 1.2e-38 167.5 Streptococcus sanguinis Bacteria 1UA7P@1239,1WRVC@1305,2AQRJ@1,31FZC@2,4IKIV@91061 NA|NA|NA BNPNBKBE_00798 1046629.Ssal_01112 6.7e-184 649.8 Bacilli lplA 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 Bacteria 1TQ5U@1239,4H9P6@91061,COG0095@1,COG0095@2 NA|NA|NA H Lipoate-protein ligase BNPNBKBE_00799 1046629.Ssal_01108 2.5e-192 677.9 Bacilli xerS GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 Bacteria 1URNQ@1239,4HEPI@91061,COG4974@1,COG4974@2 NA|NA|NA D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division BNPNBKBE_00800 1046629.Ssal_01107 0.0 1663.3 Bacilli pepN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 1TR43@1239,4HA20@91061,COG0308@1,COG0308@2 NA|NA|NA E aminopeptidase BNPNBKBE_00801 904306.HMPREF9192_1735 3.2e-113 414.5 Bacilli phoU ko:K02039 ko00000 Bacteria 1URN3@1239,4HEU9@91061,COG0704@1,COG0704@2 NA|NA|NA P Plays a role in the regulation of phosphate uptake BNPNBKBE_00802 1046629.Ssal_01105 3.9e-139 500.7 Bacilli pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 iLJ478.TM1261 Bacteria 1TP1M@1239,4HAB1@91061,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system BNPNBKBE_00803 1046629.Ssal_01104 3.4e-149 534.3 Bacilli pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 iLJ478.TM1261 Bacteria 1TP1M@1239,4HAB1@91061,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system BNPNBKBE_00804 904306.HMPREF9192_1738 9.1e-156 556.2 Bacilli pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TP74@1239,4HAKF@91061,COG0581@1,COG0581@2 NA|NA|NA P phosphate transport system permease BNPNBKBE_00805 904306.HMPREF9192_1739 7.2e-156 556.6 Bacilli pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02037 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TSPP@1239,4HC9H@91061,COG0573@1,COG0573@2 NA|NA|NA P probably responsible for the translocation of the substrate across the membrane BNPNBKBE_00806 904306.HMPREF9192_1740 2.6e-155 554.7 Bacilli pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TQ5X@1239,4HBEB@91061,COG0226@1,COG0226@2 NA|NA|NA P phosphate BNPNBKBE_00807 904306.HMPREF9192_1741 5.3e-245 853.2 Bacilli rsmF GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176,2.1.1.178 ko:K03500,ko:K11392 ko00000,ko01000,ko03009 Bacteria 1TPGQ@1239,4HCHQ@91061,COG0144@1,COG0144@2,COG3270@1,COG3270@2 NA|NA|NA J NOL1 NOP2 sun family protein BNPNBKBE_00808 1046629.Ssal_01099 2.5e-141 508.1 Bacilli suhB 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR4E@1239,4HB92@91061,COG0483@1,COG0483@2 NA|NA|NA G Belongs to the inositol monophosphatase superfamily BNPNBKBE_00809 1046629.Ssal_01098 3e-44 184.1 Bacilli yktA ko:K16509 ko00000 Bacteria 1VEK8@1239,4HNKR@91061,COG4476@1,COG4476@2 NA|NA|NA S Belongs to the UPF0223 family BNPNBKBE_00810 904306.HMPREF9192_1744 7.2e-71 273.1 Bacilli spxA 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1V3QC@1239,4HH0I@91061,COG1393@1,COG1393@2 NA|NA|NA K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress BNPNBKBE_00811 1046629.Ssal_01096 1.1e-169 602.4 Bacilli ribF 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS06310 Bacteria 1TPKS@1239,4H9KE@91061,COG0196@1,COG0196@2 NA|NA|NA H Belongs to the ribF family BNPNBKBE_00812 904306.HMPREF9192_1746 1.6e-146 525.4 Bacilli truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 ko00000,ko01000,ko03000,ko03016 iSB619.SA_RS06305 Bacteria 1TP9Y@1239,4HA9X@91061,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs BNPNBKBE_00813 1046629.Ssal_01094 1.3e-235 822.0 Bacilli XK27_04775 ko:K09155 ko00000 Bacteria 1TRD5@1239,4HAAW@91061,COG2461@1,COG2461@2 NA|NA|NA S hemerythrin HHE cation binding domain BNPNBKBE_00814 435842.HMPREF0848_00681 2.7e-35 154.1 Bacteria M1-755 ko:K09155 ko00000 Bacteria COG2461@1,COG2461@2 NA|NA|NA P Hemerythrin HHE cation binding domain protein BNPNBKBE_00815 904306.HMPREF9192_1749 1.1e-110 406.0 Bacilli hsdS2 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1VQES@1239,4HE4K@91061,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain BNPNBKBE_00816 1046629.Ssal_01091 5.5e-86 323.6 Bacilli tpx GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009405,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0020012,GO:0030312,GO:0030682,GO:0032843,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K11065 ko00000,ko01000 Bacteria 1V474@1239,4HFMW@91061,COG2077@1,COG2077@2 NA|NA|NA O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides BNPNBKBE_00817 904306.HMPREF9192_1752 1.2e-135 489.2 Bacilli Bacteria 1TQTU@1239,4HEHK@91061,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase BNPNBKBE_00818 322159.STER_0995 1.5e-239 835.1 Bacilli metY 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 Bacteria 1VYCY@1239,4H9X5@91061,COG2873@1,COG2873@2 NA|NA|NA E o-acetylhomoserine BNPNBKBE_00819 1046629.Ssal_01088 0.0 1485.3 Bacilli pcrA 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPSU@1239,4HB12@91061,COG0210@1,COG0210@2 NA|NA|NA L ATP-dependent DNA helicase BNPNBKBE_00820 1046629.Ssal_01087 8.4e-238 829.3 Bacilli agcS GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03310 ko00000 2.A.25 Bacteria 1TNZP@1239,4H9SZ@91061,COG1115@1,COG1115@2 NA|NA|NA E (Alanine) symporter BNPNBKBE_00821 1046629.Ssal_01086 2e-242 844.7 Bacilli mnmE GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K03650 R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 Bacteria 1TPJF@1239,4HA06@91061,COG0486@1,COG0486@2 NA|NA|NA S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 BNPNBKBE_00822 1046629.Ssal_01085 1.1e-173 615.9 Bacilli bglC Bacteria 1UZG6@1239,4HCQS@91061,COG2207@1,COG2207@2 NA|NA|NA K Transcriptional regulator BNPNBKBE_00823 1046629.Ssal_01083 0.0 1196.8 Bacilli sasH 3.1.3.5,3.6.1.45 ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPV2@1239,4H9VJ@91061,COG0737@1,COG0737@2 NA|NA|NA F Belongs to the 5'-nucleotidase family BNPNBKBE_00824 699248.SRA_05851 6.4e-82 310.5 Bacilli yecS GO:0000099,GO:0000101,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006791,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015184,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015811,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:0098656,GO:1901682,GO:1902475,GO:1903825,GO:1905039 ko:K10009 ko02010,map02010 M00234 ko00000,ko00001,ko00002,ko02000 3.A.1.3.10,3.A.1.3.14 iJN746.PP_0226 Bacteria 1TQ43@1239,4HCZV@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter (Permease BNPNBKBE_00825 435842.HMPREF0848_00690 1.3e-148 532.3 Bacilli yckB ko:K02030,ko:K02424 ko02010,map02010 M00234,M00236 ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3,3.A.1.3.10,3.A.1.3.14 Bacteria 1UHHG@1239,4H9NX@91061,COG0834@1,COG0834@2 NA|NA|NA ET Belongs to the bacterial solute-binding protein 3 family BNPNBKBE_00826 435842.HMPREF0848_00691 1.1e-240 839.0 Bacilli nylA 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 Bacteria 1TPGJ@1239,4HBE7@91061,COG0154@1,COG0154@2 NA|NA|NA J Belongs to the amidase family BNPNBKBE_00827 1046629.Ssal_01081 4.4e-112 410.6 Bacilli pyrE 2.4.2.10,4.1.1.23 ko:K00762,ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15560 Bacteria 1V1BZ@1239,4HFV7@91061,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) BNPNBKBE_00828 435842.HMPREF0848_00693 4.2e-124 450.7 Bacilli pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750 Bacteria 1TPPH@1239,4HAJ2@91061,COG0284@1,COG0284@2 NA|NA|NA F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) BNPNBKBE_00831 435842.HMPREF0848_00694 5e-176 623.6 Bacilli pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15540 Bacteria 1TPFV@1239,4HA5H@91061,COG0167@1,COG0167@2 NA|NA|NA F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily BNPNBKBE_00832 435842.HMPREF0848_00695 1.5e-144 518.8 Bacilli pyrK GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042602,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0052875,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 iYO844.BSU15530 Bacteria 1TQ5D@1239,4HAU4@91061,COG0543@1,COG0543@2 NA|NA|NA C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) BNPNBKBE_00833 1046629.Ssal_01076 6.1e-94 350.1 Bacilli thiJ 2.7.11.1,3.5.1.124 ko:K03152,ko:K05520,ko:K12132 ko00000,ko01000,ko01001,ko01002 Bacteria 1V3WB@1239,4HM36@91061,COG0693@1,COG0693@2 NA|NA|NA S DJ-1 family BNPNBKBE_00834 904306.HMPREF9192_1767 8e-135 486.5 Bacilli Bacteria 1V7WE@1239,2B4EH@1,31X62@2,4HJ8G@91061 NA|NA|NA S TraX protein BNPNBKBE_00835 1046629.Ssal_01074 1.5e-305 1054.7 Bacilli FbpA ko:K12341 ko03070,map03070 ko00000,ko00001,ko02044 1.B.40.1.1 Bacteria 1TQ8A@1239,4H9UF@91061,COG1293@1,COG1293@2 NA|NA|NA K RNA-binding protein homologous to eukaryotic snRNP BNPNBKBE_00836 1046629.Ssal_01073 2.8e-277 960.7 Bacilli Bacteria 1UK4X@1239,2DM53@1,31R8Y@2,4IU8I@91061 NA|NA|NA S Psort location CytoplasmicMembrane, score BNPNBKBE_00837 1046629.Ssal_01071 9e-232 809.3 Bacilli dinF Bacteria 1TNZN@1239,4HANM@91061,COG0534@1,COG0534@2 NA|NA|NA V Mate efflux family protein BNPNBKBE_00838 1046629.Ssal_01070 6.6e-176 623.2 Bacilli yclQ ko:K02016 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 1UXCZ@1239,4HAMP@91061,COG4607@1,COG4607@2 NA|NA|NA P ABC-type enterochelin transport system, periplasmic component BNPNBKBE_00839 435842.HMPREF0848_00708 0.0 1415.2 Bacilli Bacteria 1TRA8@1239,4HCIF@91061,COG1061@1,COG1061@2 NA|NA|NA V Type III restriction enzyme, res subunit BNPNBKBE_00840 264199.stu0942 6e-109 400.2 Bacilli gph 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPPZ@1239,4IPIP@91061,COG0546@1,COG0546@2 NA|NA|NA S HAD hydrolase, family IA, variant 1 BNPNBKBE_00841 264199.stu0941 3.5e-140 504.2 Bacilli 2.4.2.3 ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01876,R02484,R08229 RC00063 ko00000,ko00001,ko01000 Bacteria 1TQ71@1239,4HUI7@91061,COG2820@1,COG2820@2 NA|NA|NA F Phosphorylase superfamily BNPNBKBE_00842 904306.HMPREF9192_1774 1.5e-109 402.1 Bacilli Bacteria 1VBV2@1239,4IPU4@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family BNPNBKBE_00843 435842.HMPREF0848_00712 1.8e-177 628.6 Bacilli ybhR ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQG7@1239,4H9MK@91061,COG0842@1,COG0842@2 NA|NA|NA V ABC transporter BNPNBKBE_00844 888833.HMPREF9421_1648 1e-125 456.1 Bacilli ybhF_2 ko:K01990,ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQKM@1239,4HBUK@91061,COG1131@1,COG1131@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_00847 1114965.Spaf_1743 4.9e-138 497.3 Firmicutes Bacteria 1V01B@1239,COG4814@1,COG4814@2 NA|NA|NA G protein with an alpha beta hydrolase fold BNPNBKBE_00848 435842.HMPREF0848_00714 1.1e-85 322.8 Bacilli spxB 1.2.3.3,1.2.5.1 ko:K00156,ko:K00158 ko00620,ko01100,map00620,map01100 R00207,R03145 RC00860,RC02745 ko00000,ko00001,ko01000 Bacteria 1TQE8@1239,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family BNPNBKBE_00849 904306.HMPREF9192_1780 0.0 1379.0 Bacilli copA 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 1TP5S@1239,4HAI0@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase BNPNBKBE_00850 888808.HMPREF9380_0350 4.8e-66 256.9 Streptococcus sanguinis silP 1.9.3.1,3.6.3.54 ko:K02275,ko:K17686 ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016 M00155 R00081,R00086 RC00002,RC00016 ko00000,ko00001,ko00002,ko01000 3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 1VE0E@1239,1WS61@1305,4HMFJ@91061,COG4633@1,COG4633@2 NA|NA|NA S Cupredoxin-like domain BNPNBKBE_00851 435842.HMPREF0848_00717 1.4e-63 248.8 Bacilli copY Bacteria 1VEJ8@1239,4HYMC@91061,COG3682@1,COG3682@2 NA|NA|NA K Copper transport repressor, CopY TcrY family BNPNBKBE_00852 904306.HMPREF9192_1783 1.9e-189 668.3 Bacilli adhB 1.1.1.1,1.1.1.14 ko:K00001,ko:K00008 ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 M00014 R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPIW@1239,4HB2G@91061,COG1063@1,COG1063@2 NA|NA|NA E Dehydrogenase BNPNBKBE_00853 999425.HMPREF9186_00908 6.7e-193 679.9 Bacilli hemH GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPKF@1239,4HAYG@91061,COG0276@1,COG0276@2 NA|NA|NA H Catalyzes the ferrous insertion into protoporphyrin IX BNPNBKBE_00854 435842.HMPREF0848_00730 5.2e-151 540.4 Bacilli czcD ko:K16264 ko00000,ko02000 2.A.4.1 Bacteria 1TR92@1239,4HBCQ@91061,COG1230@1,COG1230@2 NA|NA|NA P cation diffusion facilitator family transporter BNPNBKBE_00855 322159.STER_0946 1e-99 369.4 Bacilli Bacteria 1TSUJ@1239,4IPZN@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator, TetR family BNPNBKBE_00856 888048.HMPREF8577_1220 1.6e-58 232.3 Firmicutes Bacteria 1VA8B@1239,2BS9S@1,32XMN@2 NA|NA|NA S Protein of unknown function with HXXEE motif BNPNBKBE_00857 888048.HMPREF8577_1221 1.7e-38 165.2 Bacilli Bacteria 1W4NX@1239,2DD3F@1,2ZGBB@2,4I0KR@91061 NA|NA|NA BNPNBKBE_00858 999425.HMPREF9186_00913 2.1e-152 545.0 Bacilli Bacteria 1TRQB@1239,4HAY3@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Belongs to the short-chain dehydrogenases reductases (SDR) family BNPNBKBE_00859 889204.HMPREF9423_1742 1.6e-154 552.0 Streptococcus infantis Bacteria 1UWGW@1239,43GIA@68892,4IDYE@91061,COG2267@1,COG2267@2 NA|NA|NA I Alpha/beta hydrolase family BNPNBKBE_00860 999425.HMPREF9186_00915 2.8e-177 627.9 Bacilli 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1TQ0M@1239,4HA8M@91061,COG0604@1,COG0604@2 NA|NA|NA C nadph quinone reductase BNPNBKBE_00861 889204.HMPREF9423_1744 3.2e-66 257.7 Bacilli Bacteria 1V53C@1239,4HN6G@91061,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator BNPNBKBE_00862 999425.HMPREF9186_00918 7e-62 243.0 Bacilli pnuC ko:K03811 ko00000,ko02000 4.B.1.1 Bacteria 1UYDN@1239,4HJE5@91061,COG3201@1,COG3201@2 NA|NA|NA H nicotinamide mononucleotide transporter BNPNBKBE_00863 435842.HMPREF0848_00734 3.9e-150 537.3 Bacilli cbiO2 ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1VSUE@1239,4HT6W@91061,COG1122@1,COG1122@2 NA|NA|NA P ABC transporter, ATP-binding protein BNPNBKBE_00864 435842.HMPREF0848_00735 1.7e-156 558.5 Bacteria ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria COG1122@1,COG1122@2 NA|NA|NA P ATPase activity BNPNBKBE_00865 888048.HMPREF8577_1226 4.4e-133 480.7 Bacilli cbiQ ko:K02008,ko:K16785 ko02010,map02010 M00245,M00246,M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1UYQQ@1239,4HFDP@91061,COG0619@1,COG0619@2 NA|NA|NA P cobalt transport BNPNBKBE_00866 1316408.HSISM1_2045 4.8e-92 344.0 Firmicutes 2.7.7.65 ko:K16923,ko:K18967 M00582 ko00000,ko00002,ko01000,ko02000 3.A.1.28,9.B.34.1.1 Bacteria 1V65C@1239,COG3275@1,COG3275@2 NA|NA|NA T Psort location CytoplasmicMembrane, score BNPNBKBE_00867 435842.HMPREF0848_00738 1.5e-138 498.8 Bacilli Bacteria 1TPPX@1239,4HDAC@91061,COG0384@1,COG0384@2 NA|NA|NA S Phenazine biosynthesis protein BNPNBKBE_00868 1316408.HSISM1_517 5.7e-92 343.6 Bacteria tetR Bacteria COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator BNPNBKBE_00869 888048.HMPREF8577_1791 7.3e-124 449.9 Bacilli ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQC9@1239,4HB8D@91061,COG1136@1,COG1136@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_00870 1316408.HSISM1_519 0.0 1550.4 Bacilli ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPHU@1239,4HA2C@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter (Permease BNPNBKBE_00871 888048.HMPREF8577_1788 3.7e-35 153.7 Firmicutes ko:K07497 ko00000 Bacteria 1TQQY@1239,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain protein BNPNBKBE_00872 888048.HMPREF8577_1787 2e-109 401.7 Bacilli magIII ko:K07457 ko00000 Bacteria 1V4SG@1239,4HI5U@91061,COG2231@1,COG2231@2 NA|NA|NA L Base excision DNA repair protein, HhH-GPD family BNPNBKBE_00873 888048.HMPREF8577_1786 3.8e-263 913.7 Bacilli proWX ko:K05845,ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1TQ7D@1239,4HBDR@91061,COG1174@1,COG1174@2,COG1732@1,COG1732@2 NA|NA|NA P ABC transporter BNPNBKBE_00874 1095726.HMPREF1116_1096 7e-130 469.9 Bacilli proV ko:K05847 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1TPV8@1239,4H9SI@91061,COG1125@1,COG1125@2 NA|NA|NA E abc transporter atp-binding protein BNPNBKBE_00875 435842.HMPREF0848_00741 8.6e-168 596.3 Bacilli Bacteria 1V55H@1239,4HD0S@91061,COG0604@1,COG0604@2 NA|NA|NA C alcohol dehydrogenase BNPNBKBE_00876 1005705.HMPREF9967_0601 2.2e-135 488.4 Streptococcus infantis 1.6.5.2 ko:K19267 ko00130,ko01110,map00130,map01110 R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 Bacteria 1TWJX@1239,43GGB@68892,4I5DF@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family BNPNBKBE_00877 176090.SSIN_1789 8.9e-67 259.6 Bacilli mgrA ko:K06075 ko00000,ko03000 Bacteria 1VDJQ@1239,4HN0M@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator, MarR family BNPNBKBE_00878 658088.HMPREF0987_00818 8.8e-78 297.0 unclassified Lachnospiraceae Bacteria 1TQSZ@1239,24935@186801,27TKJ@186928,COG2110@1,COG2110@2 NA|NA|NA S Macro domain BNPNBKBE_00879 1123298.KB904062_gene948 2.4e-94 352.1 Bacilli Bacteria 1TQB7@1239,4HAQT@91061,COG0846@1,COG0846@2 NA|NA|NA K COG COG0846 NAD-dependent protein deacetylases, SIR2 family BNPNBKBE_00880 1123298.KB904062_gene947 2.6e-39 168.3 Bacilli Bacteria 1TR2Q@1239,4HHXT@91061,COG5015@1,COG5015@2 NA|NA|NA C Pyridoxamine 5'-phosphate oxidase BNPNBKBE_00881 322159.STER_0941 8.8e-133 479.6 Bacilli budA GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0047605 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 R02948 RC00812 ko00000,ko00001,ko01000 Bacteria 1V4AH@1239,4HJ98@91061,COG3527@1,COG3527@2 NA|NA|NA H Belongs to the alpha-acetolactate decarboxylase family BNPNBKBE_00882 1046629.Ssal_01037 0.0 1102.8 Bacilli alsS 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQE8@1239,4HAV1@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family BNPNBKBE_00885 1046629.Ssal_01034 0.0 1173.3 Bacilli lepA ko:K03596 ko05134,map05134 ko00000,ko00001 Bacteria 1TP0G@1239,4HASA@91061,COG0481@1,COG0481@2 NA|NA|NA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner BNPNBKBE_00887 435842.HMPREF0848_00749 8.2e-137 493.0 Bacilli Bacteria 1TRQC@1239,4HD7P@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Acetoin reductase BNPNBKBE_00888 904306.HMPREF9192_1808 2.2e-45 188.0 Firmicutes pspE ko:K03972 ko00000 Bacteria 1U0PW@1239,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese-like protein BNPNBKBE_00889 264199.stu0906 5.5e-71 273.5 Firmicutes ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 Bacteria 1V44G@1239,COG0105@1,COG0105@2 NA|NA|NA F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate BNPNBKBE_00890 1046629.Ssal_01022 1e-223 782.3 Bacilli XK27_05470 Bacteria 1TPDQ@1239,4HADW@91061,COG0620@1,COG0620@2 NA|NA|NA E Methionine synthase BNPNBKBE_00891 1046629.Ssal_01021 2.4e-256 891.0 Bacilli trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 ko00000,ko01000,ko03016,ko03036 Bacteria 1TP67@1239,4HB27@91061,COG1206@1,COG1206@2 NA|NA|NA J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs BNPNBKBE_00892 264199.stu0902 3.2e-221 774.2 Bacilli Bacteria 1TS1G@1239,4HEWT@91061,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor BNPNBKBE_00893 904306.HMPREF9192_1813 5.1e-119 433.7 Bacilli Bacteria 1TQ0D@1239,4HDA9@91061,COG0745@1,COG0745@2 NA|NA|NA KT Transcriptional regulatory protein, C terminal BNPNBKBE_00894 904306.HMPREF9192_1814 2.1e-146 525.0 Bacilli Bacteria 1V2FW@1239,2DC01@1,2ZC51@2,4HG69@91061 NA|NA|NA S TraX protein BNPNBKBE_00896 862967.SIR_0964 5.3e-53 214.5 Bacteria ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 M00817 ko00000,ko00001,ko00002,ko02000 3.A.1.124.1,3.A.1.124.2,3.A.1.124.6 Bacteria COG4200@1,COG4200@2 NA|NA|NA V ABC-2 family transporter protein BNPNBKBE_00897 1069533.Sinf_0951 2.1e-83 315.5 Bacilli mutF ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 M00254,M00817 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.124.1,3.A.1.124.2,3.A.1.124.6 Bacteria 1VVRQ@1239,4HWA2@91061,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system BNPNBKBE_00898 1046629.Ssal_01017 0.0 1330.1 Bacilli topA 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria 1TPUS@1239,4HA6C@91061,COG0550@1,COG0550@2 NA|NA|NA L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone BNPNBKBE_00899 1046629.Ssal_01014 7e-158 563.1 Bacilli dprA GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 ko:K04096 ko00000 Bacteria 1TPP7@1239,4HGWM@91061,COG0758@1,COG0758@2 NA|NA|NA LU DNA protecting protein DprA BNPNBKBE_00900 1046629.Ssal_01013 1.4e-162 578.9 Firmicutes Bacteria 1TRQ7@1239,COG1940@1,COG1940@2 NA|NA|NA GK ROK family BNPNBKBE_00901 1046629.Ssal_01011 8.5e-134 483.0 Bacilli rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1V1D6@1239,4HB7M@91061,COG0164@1,COG0164@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids BNPNBKBE_00902 435842.HMPREF0848_00760 2.1e-157 561.6 Bacilli ylqF GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 ko:K14540 ko00000,ko03009 Bacteria 1TQGK@1239,4HA4D@91061,COG1161@1,COG1161@2 NA|NA|NA S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity BNPNBKBE_00903 435842.HMPREF0848_00761 4.8e-128 463.8 Bacilli Bacteria 1V758@1239,4HIKZ@91061,COG1396@1,COG1396@2,COG2932@1,COG2932@2 NA|NA|NA K DNA-binding helix-turn-helix protein BNPNBKBE_00904 435842.HMPREF0848_00762 4.6e-91 340.5 Bacilli niaR ko:K07105 ko00000 Bacteria 1V6EY@1239,4HGYB@91061,COG1827@1,COG1827@2 NA|NA|NA S small molecule binding protein (contains 3H domain) BNPNBKBE_00905 435842.HMPREF0848_00763 5.3e-87 327.0 Firmicutes ko:K16788 ko00000,ko02000 2.A.88.5 Bacteria 1VDRR@1239,2A1RE@1,32VI2@2 NA|NA|NA BNPNBKBE_00906 1046629.Ssal_01006 3.8e-274 950.3 Bacilli ffh GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 1TP06@1239,4H9T4@91061,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY BNPNBKBE_00907 435842.HMPREF0848_00765 2e-55 221.5 Bacilli ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 ko:K09787 ko00000 Bacteria 1VEGP@1239,4HKK6@91061,COG2739@1,COG2739@2 NA|NA|NA S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein BNPNBKBE_00908 435842.HMPREF0848_00766 2.2e-125 454.9 Bacilli gntR1 ko:K03710,ko:K11922 ko00000,ko03000 Bacteria 1UYBW@1239,4HDDG@91061,COG2188@1,COG2188@2 NA|NA|NA K transcriptional BNPNBKBE_00909 904306.HMPREF9192_1826 1.8e-303 1047.7 Bacilli guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 ko:K01951,ko:K03790 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002,ko03009 iJN746.PP_1032,iLJ478.TM1820,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833 Bacteria 1TPG8@1239,4HA7Q@91061,COG0518@1,COG0518@2,COG0519@1,COG0519@2 NA|NA|NA F Catalyzes the synthesis of GMP from XMP BNPNBKBE_00910 904306.HMPREF9192_1827 7.9e-188 662.9 Bacilli adhP GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0006081,GO:0006117,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009636,GO:0009987,GO:0010033,GO:0016491,GO:0016614,GO:0016616,GO:0033554,GO:0042221,GO:0042493,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0045471,GO:0046185,GO:0046187,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0097305,GO:1901575,GO:1901700 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 iECP_1309.ECP_1480 Bacteria 1TP5B@1239,4HA9Z@91061,COG1064@1,COG1064@2 NA|NA|NA C alcohol dehydrogenase BNPNBKBE_00911 1046629.Ssal_00990 1.3e-44 185.3 Firmicutes Bacteria 1VFJD@1239,2E660@1,330UP@2 NA|NA|NA BNPNBKBE_00912 435842.HMPREF0848_00770 2.7e-48 198.0 Bacilli Bacteria 1VFMU@1239,2E59Z@1,33028@2,4HQG9@91061 NA|NA|NA BNPNBKBE_00913 904306.HMPREF9192_1830 1.7e-265 921.4 Bacilli uvrX 2.7.7.7 ko:K02346,ko:K03502,ko:K14161 ko00000,ko01000,ko03400 Bacteria 1TP42@1239,4HA1P@91061,COG0389@1,COG0389@2 NA|NA|NA L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII BNPNBKBE_00914 1046629.Ssal_00988 4.8e-154 550.4 Firmicutes aatB ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TQNR@1239,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter substrate-binding protein BNPNBKBE_00915 1046629.Ssal_00987 8.8e-113 412.9 Bacilli glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1UYAZ@1239,4HE6M@91061,COG1126@1,COG1126@2 NA|NA|NA E abc transporter atp-binding protein BNPNBKBE_00916 1046629.Ssal_00986 1.4e-105 389.0 Bacilli artQ ko:K02029,ko:K02030,ko:K17073,ko:K17074 ko02010,map02010 M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1V280@1239,4HGMH@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter (Permease BNPNBKBE_00917 1046629.Ssal_00985 6.6e-59 233.0 Bacilli phnA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06193 ko01120,map01120 ko00000 Bacteria 1V6NA@1239,4HIKN@91061,COG2824@1,COG2824@2 NA|NA|NA P Alkylphosphonate utilization operon protein PhnA BNPNBKBE_00918 1046629.Ssal_00983 0.0 1153.3 Bacilli glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 iNJ661.Rv3436c,iSB619.SA_RS11245,iYO844.BSU01780 Bacteria 1TPGU@1239,4H9R4@91061,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source BNPNBKBE_00919 1046629.Ssal_00982 8.4e-165 586.3 Bacilli cpsY Bacteria 1TP3E@1239,4HC5J@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator BNPNBKBE_00920 1046629.Ssal_00980 3.5e-126 457.6 Bacilli mur1 3.4.17.14,3.5.1.28 ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 M00651,M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 Bacteria 1UYRM@1239,4HAU6@91061,COG1705@1,COG1705@2 NA|NA|NA NU muramidase BNPNBKBE_00921 1046629.Ssal_00979 1.9e-170 605.1 Firmicutes yeiH Bacteria 1TQYA@1239,COG2855@1,COG2855@2 NA|NA|NA S Membrane BNPNBKBE_00923 663952.SDD27957_05960 3.4e-09 68.2 Streptococcus dysgalactiae group Bacteria 1M9M6@119603,1TXBA@1239,2DJ70@1,304WJ@2,4I68X@91061 NA|NA|NA BNPNBKBE_00924 1046629.Ssal_00976 9.9e-283 978.8 Bacilli adcA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0007154,GO:0008150,GO:0008270,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0030288,GO:0030313,GO:0031667,GO:0031668,GO:0031669,GO:0031975,GO:0033554,GO:0034224,GO:0042221,GO:0042594,GO:0042597,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046686,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0120127 ko:K09815 ko02010,map02010 M00242 ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 Bacteria 1TPG7@1239,4H9UN@91061,COG0803@1,COG0803@2,COG3443@1,COG3443@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family BNPNBKBE_00925 1046629.Ssal_00975 6.1e-146 523.5 Bacteria XK27_10720 Bacteria COG2339@1,COG2339@2 NA|NA|NA D peptidase activity BNPNBKBE_00926 1046629.Ssal_00974 3.6e-276 956.8 Bacilli pepD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase BNPNBKBE_00927 1046629.Ssal_00973 2.2e-160 571.6 Bacilli whiA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944 ko:K09762 ko00000 Bacteria 1TP2X@1239,4HB4H@91061,COG1481@1,COG1481@2 NA|NA|NA K May be required for sporulation BNPNBKBE_00928 1046629.Ssal_00972 1.8e-181 641.7 Bacilli ybhK Bacteria 1TPNV@1239,4HA0Z@91061,COG0391@1,COG0391@2 NA|NA|NA S Required for morphogenesis under gluconeogenic growth conditions BNPNBKBE_00929 1046629.Ssal_00971 5.5e-161 573.5 Bacilli rapZ GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K06958 ko00000,ko03019 Bacteria 1TPS4@1239,4H9KM@91061,COG1660@1,COG1660@2 NA|NA|NA S Displays ATPase and GTPase activities BNPNBKBE_00930 1046629.Ssal_00970 3.8e-134 484.2 Bacilli yejC Bacteria 1V46X@1239,4HI49@91061,COG4420@1,COG4420@2 NA|NA|NA S cyclic nucleotide-binding protein BNPNBKBE_00931 1046629.Ssal_00969 3.9e-202 711.4 Bacteria Bacteria COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation BNPNBKBE_00932 904306.HMPREF9192_1256 1.4e-94 352.1 Bacilli queF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016657,GO:0018130,GO:0019438,GO:0033739,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.7.1.13 ko:K06879,ko:K09457 ko00790,ko01100,map00790,map01100 R07605 RC01875 ko00000,ko00001,ko01000,ko03016 iSFV_1184.SFV_2663,iSF_1195.SF2807,iS_1188.S3002 Bacteria 1TPYC@1239,4HB14@91061,COG0780@1,COG0780@2 NA|NA|NA S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily BNPNBKBE_00933 904306.HMPREF9192_1255 1.2e-134 485.7 Bacilli queE GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 1.97.1.4,4.3.99.3 ko:K04068,ko:K10026 ko00790,ko01100,map00790,map01100 R04710,R10002 RC02989 ko00000,ko00001,ko01000,ko03016 Bacteria 1TQ58@1239,4HAJ3@91061,COG0602@1,COG0602@2 NA|NA|NA H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds BNPNBKBE_00934 1046629.Ssal_00964 8.8e-83 312.8 Bacilli queD 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1V9HU@1239,4HJEX@91061,COG0720@1,COG0720@2 NA|NA|NA H synthase BNPNBKBE_00935 1046629.Ssal_00963 1.2e-123 449.1 Bacilli queC 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 R09978 RC00959 ko00000,ko00001,ko01000,ko03016 Bacteria 1TP4Z@1239,4HB1Y@91061,COG0603@1,COG0603@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) BNPNBKBE_00936 1046629.Ssal_00962 3e-63 247.7 Bacilli tdcF 3.5.99.10 ko:K09022 R11098,R11099 RC03275,RC03354 ko00000,ko01000 Bacteria 1V6HG@1239,4HKEF@91061,COG0251@1,COG0251@2 NA|NA|NA J endoribonuclease L-PSP BNPNBKBE_00937 562983.HMPREF0433_01645 4.8e-19 100.9 Bacilli Bacteria 1W2BC@1239,2DF7W@1,2ZQU2@2,4HZFK@91061 NA|NA|NA BNPNBKBE_00938 904306.HMPREF9192_1250 1e-259 902.1 Bacilli asnS GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP38@1239,4H9YH@91061,COG0017@1,COG0017@2 NA|NA|NA J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA BNPNBKBE_00939 264199.stu0817 2.8e-213 747.7 Bacilli aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 iHN637.CLJU_RS06550 Bacteria 1TP0J@1239,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase BNPNBKBE_00940 1046629.Ssal_00958 3e-76 291.2 Bacilli ypmB Bacteria 1VA2H@1239,4HNMM@91061,COG5353@1,COG5353@2 NA|NA|NA S Protein conserved in bacteria BNPNBKBE_00941 1046629.Ssal_00957 0.0 1545.0 Bacilli dinG GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.6.4.12 ko:K02342,ko:K03722 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TQHQ@1239,4HB2Y@91061,COG1199@1,COG1199@2,COG2176@1,COG2176@2 NA|NA|NA L helicase involved in DNA repair and perhaps also replication BNPNBKBE_00942 1046629.Ssal_00954 3e-113 414.5 Bacilli ycbL GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 ko:K01069 ko00620,map00620 R01736 RC00004,RC00137 ko00000,ko00001,ko01000 Bacteria 1V6FA@1239,4HHRQ@91061,COG0491@1,COG0491@2 NA|NA|NA S COG0491 Zn-dependent hydrolases, including glyoxylases BNPNBKBE_00943 435842.HMPREF0848_00800 2.3e-168 598.2 Bacilli yufQ ko:K02057 M00221 ko00000,ko00002,ko02000 3.A.1.2 Bacteria 1TP8Y@1239,4HAX4@91061,COG1079@1,COG1079@2 NA|NA|NA S Belongs to the binding-protein-dependent transport system permease family BNPNBKBE_00944 435842.HMPREF0848_00801 2.3e-177 628.2 Bacilli yufP GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 ko:K02057 M00221 ko00000,ko00002,ko02000 3.A.1.2 Bacteria 1TP1F@1239,4H9VE@91061,COG4603@1,COG4603@2 NA|NA|NA S Belongs to the binding-protein-dependent transport system permease family BNPNBKBE_00945 435842.HMPREF0848_00802 1.7e-279 968.0 Bacilli xylG 3.6.3.17 ko:K02056,ko:K06400 M00221 ko00000,ko00002,ko01000,ko02000 3.A.1.2 Bacteria 1UYQA@1239,4HVSH@91061,COG3845@1,COG3845@2 NA|NA|NA S ABC transporter, ATP-binding protein BNPNBKBE_00946 1046629.Ssal_00950 6.2e-191 673.3 Bacilli tcsA ko:K02058,ko:K07335 M00221 ko00000,ko00002,ko02000 3.A.1.2 Bacteria 1TPEU@1239,4HF7R@91061,COG1744@1,COG1744@2 NA|NA|NA S membrane BNPNBKBE_00947 1046629.Ssal_00949 7.4e-65 253.1 Bacilli cdd 2.4.2.2,3.5.4.5 ko:K00756,ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01570,R01876,R01878,R02296,R02484,R02485,R08221 RC00063,RC00074,RC00514 ko00000,ko00001,ko01000 iSB619.SA_RS07895 Bacteria 1V6IP@1239,4HIJ3@91061,COG0295@1,COG0295@2 NA|NA|NA F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis BNPNBKBE_00948 1046629.Ssal_00948 3.9e-111 407.5 Bacilli deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4,5.4.2.8 ko:K01619,ko:K01840 ko00030,ko00051,ko00520,ko01100,ko01110,ko01130,map00030,map00051,map00520,map01100,map01110,map01130 M00114 R01066,R01818 RC00408,RC00436,RC00437 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS00835 Bacteria 1TPAJ@1239,4HAAJ@91061,COG0274@1,COG0274@2 NA|NA|NA F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate BNPNBKBE_00949 1046629.Ssal_00947 3.2e-226 790.8 Bacilli pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016757,GO:0016758,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 R01570,R01876,R02296,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 Bacteria 1TPCH@1239,4H9NP@91061,COG0213@1,COG0213@2 NA|NA|NA F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate BNPNBKBE_00950 1046629.Ssal_00946 5.4e-104 383.6 Bacilli rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1V3JX@1239,4IR00@91061,COG2813@1,COG2813@2 NA|NA|NA J Methyltransferase small domain protein BNPNBKBE_00951 1046629.Ssal_00945 2.6e-169 601.3 Bacilli coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECDH1ME8569_1439.ECDH1ME8569_3838,iECH74115_1262.ECH74115_5439,iECSE_1348.ECSE_4265,iECSF_1327.ECSF_3833,iECSP_1301.ECSP_5045,iECW_1372.ECW_m4332,iEcDH1_1363.EcDH1_4016,iEcolC_1368.EcolC_4046,iPC815.YPO3758,iSFV_1184.SFV_4047,iSFxv_1172.SFxv_4418,iWFL_1372.ECW_m4332,iZ_1308.Z5545 Bacteria 1TPHJ@1239,4HA4K@91061,COG1072@1,COG1072@2 NA|NA|NA F Pantothenic acid kinase BNPNBKBE_00952 904306.HMPREF9192_1235 1e-29 135.6 Bacilli rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02968 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEGX@1239,4HNJS@91061,COG0268@1,COG0268@2 NA|NA|NA J Binds directly to 16S ribosomal RNA BNPNBKBE_00953 904306.HMPREF9192_1234 6.4e-236 823.2 Bacilli Bacteria 1UHNC@1239,4IS4A@91061,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor BNPNBKBE_00954 1046629.Ssal_00942 6.1e-120 436.8 Bacilli Bacteria 1V295@1239,4HG3X@91061,COG0745@1,COG0745@2 NA|NA|NA T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain BNPNBKBE_00955 1046629.Ssal_00941 0.0 1089.3 Bacilli fhs GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP6N@1239,4HA2X@91061,COG2759@1,COG2759@2 NA|NA|NA F Belongs to the formate--tetrahydrofolate ligase family BNPNBKBE_00956 1046629.Ssal_00940 7.1e-116 423.3 Bacilli coaB 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038,ko:K21977 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 Bacteria 1V7YG@1239,4HMIF@91061,COG0452@1,COG0452@2 NA|NA|NA H Phosphopantothenate-cysteine ligase BNPNBKBE_00957 1046629.Ssal_00939 9.1e-90 336.3 Bacilli coaBC 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038,ko:K21977 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPP3@1239,4HAK8@91061,COG0452@1,COG0452@2 NA|NA|NA H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine BNPNBKBE_00958 1046629.Ssal_00938 4.1e-93 347.4 Bacilli panT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1V2M1@1239,4HFPD@91061,COG4684@1,COG4684@2 NA|NA|NA S ECF transporter, substrate-specific component BNPNBKBE_00959 1046629.Ssal_00935 0.0 1118.2 Bacilli pgm GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2,5.4.2.8 ko:K01835,ko:K01840 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114,M00549 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP2N@1239,4HADU@91061,COG1109@1,COG1109@2 NA|NA|NA G Phosphoglucomutase BNPNBKBE_00960 1046629.Ssal_00934 2.2e-162 578.2 Firmicutes metF GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 ko:K00297,ko:K21010 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,ko02025,map00670,map00720,map01100,map01120,map01200,map01523,map02025 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 iPC815.YPO0117,iSBO_1134.SBO_3961 Bacteria 1TQFE@1239,COG0685@1,COG0685@2 NA|NA|NA E reductase BNPNBKBE_00961 1046629.Ssal_00933 0.0 1483.0 Bacilli metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131 Bacteria 1TP2H@1239,4H9QC@91061,COG0620@1,COG0620@2 NA|NA|NA E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation BNPNBKBE_00963 1046629.Ssal_00931 0.0 1085.1 Bacilli pabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85,4.1.3.27,4.1.3.38 ko:K01665,ko:K02619,ko:K03342,ko:K13503,ko:K13950 ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01716,R05553 RC00010,RC01418,RC01843,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TQAP@1239,4HBKC@91061,COG0115@1,COG0115@2,COG0147@1,COG0147@2 NA|NA|NA EH component I BNPNBKBE_00964 1046629.Ssal_00930 0.0 1624.4 Bacilli 3.6.3.8 ko:K01537,ko:K12955 ko00000,ko01000 3.A.3.2,3.A.3.24 Bacteria 1TPF5@1239,4H9S5@91061,COG0474@1,COG0474@2 NA|NA|NA P cation transport ATPase BNPNBKBE_00965 1046629.Ssal_00929 1.2e-238 832.0 Bacilli dltD ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1TSZU@1239,4HC3H@91061,COG3966@1,COG3966@2 NA|NA|NA M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) BNPNBKBE_00966 1046629.Ssal_00928 2.2e-35 154.5 Bacilli dltC GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K02078,ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1VFQI@1239,4HNIH@91061,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall BNPNBKBE_00967 1046629.Ssal_00927 4.7e-235 820.1 Bacilli dltB ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1TP52@1239,4HBQG@91061,COG1696@1,COG1696@2 NA|NA|NA M Membrane protein involved in D-alanine export BNPNBKBE_00968 1046629.Ssal_00926 1.4e-297 1028.1 Bacilli dltA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1TPTH@1239,4HAHU@91061,COG1020@1,COG1020@2 NA|NA|NA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall BNPNBKBE_00969 1046629.Ssal_00924 0.0 1078.2 Bacilli XK27_10035 ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,4HCVN@91061,COG1132@1,COG1132@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_00970 904306.HMPREF9192_1216 5.9e-292 1009.6 Bacilli yfiB1 ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,4H9SC@91061,COG1132@1,COG1132@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_00971 264199.stu0757 1.4e-99 369.0 Bacteria pvaA ko:K02395 ko00000,ko02035 Bacteria COG0741@1,COG0741@2 NA|NA|NA M lytic transglycosylase activity BNPNBKBE_00972 904306.HMPREF9192_1214 1.2e-177 629.0 Bacilli ndpA GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003727,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0009295,GO:0042802,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0097159,GO:1901363 ko:K06899 ko00000,ko03036 Bacteria 1V437@1239,4IQXJ@91061,COG3081@1,COG3081@2 NA|NA|NA S 37-kD nucleoid-associated bacterial protein BNPNBKBE_00973 904306.HMPREF9192_1213 4.6e-230 803.5 Bacilli glyA 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQVM@1239,4HA5K@91061,COG0112@1,COG0112@2 NA|NA|NA E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism BNPNBKBE_00974 1046629.Ssal_00919 1.9e-104 385.2 Bacilli ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87,3.1.3.48 ko:K01104,ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 1TP1I@1239,4HA7W@91061,COG0009@1,COG0009@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine BNPNBKBE_00975 904306.HMPREF9192_1211 1.5e-139 502.3 Bacilli prmB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564 2.1.1.297,2.1.1.298 ko:K02493,ko:K07320 R10806 RC00003,RC03279 ko00000,ko01000,ko03009,ko03012 Bacteria 1TSMA@1239,4HC6W@91061,COG2890@1,COG2890@2 NA|NA|NA J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif BNPNBKBE_00976 1046629.Ssal_00917 3.6e-191 674.1 Bacilli prfA ko:K02835 ko00000,ko03012 Bacteria 1TQ7V@1239,4H9MB@91061,COG0216@1,COG0216@2 NA|NA|NA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA BNPNBKBE_00977 904306.HMPREF9192_1209 1.9e-109 401.7 Bacilli tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 iAF1260.b1238,iBWG_1329.BWG_1065,iECDH10B_1368.ECDH10B_1298,iECDH1ME8569_1439.ECDH1ME8569_1176,iEcDH1_1363.EcDH1_2411,iJO1366.b1238,iJR904.b1238,iPC815.YPO2176,iY75_1357.Y75_RS06470 Bacteria 1TRVM@1239,4HA4A@91061,COG1435@1,COG1435@2 NA|NA|NA F thymidine kinase BNPNBKBE_00978 1046629.Ssal_00915 1.6e-185 655.2 Bacilli add 3.5.4.4 ko:K01488,ko:K02029 ko00230,ko01100,ko05340,map00230,map01100,map05340 M00236 R01560,R02556 RC00477 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 iHN637.CLJU_RS13960 Bacteria 1U44B@1239,4HCES@91061,COG1816@1,COG1816@2 NA|NA|NA F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism BNPNBKBE_00979 1046629.Ssal_00914 9.3e-152 542.7 Bacilli gst ko:K11209 ko00000,ko01000 Bacteria 1TPZ7@1239,4HD0K@91061,COG0625@1,COG0625@2 NA|NA|NA O Glutathione S-transferase BNPNBKBE_00980 1046629.Ssal_00913 2.5e-175 621.3 Bacilli nrnA GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPXX@1239,4H9ZW@91061,COG0618@1,COG0618@2 NA|NA|NA S domain protein BNPNBKBE_00981 1046629.Ssal_00912 1.9e-172 611.7 Bacilli apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 1TR9C@1239,4HDFE@91061,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein BNPNBKBE_00982 1046629.Ssal_00910 4.4e-45 186.8 Bacilli rpmE2 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEGU@1239,4HNQF@91061,COG0254@1,COG0254@2 NA|NA|NA J 50S ribosomal protein L31 BNPNBKBE_00983 1046629.Ssal_00908 4.7e-230 803.5 Bacilli mntH Bacteria 1V04N@1239,4HBF6@91061,COG1914@1,COG1914@2 NA|NA|NA P Mn2 and Fe2 transporters of the NRAMP family BNPNBKBE_00984 1046629.Ssal_00907 2.2e-163 581.6 Bacilli ypuA Bacteria 1TR2I@1239,4HBVZ@91061,COG4086@1,COG4086@2 NA|NA|NA S secreted protein BNPNBKBE_00985 1095738.HMPREF1047_1139 6e-204 717.6 Streptococcus oralis Bacteria 1UN93@1239,1WQ05@1303,29YAF@1,30K4J@2,4IU86@91061 NA|NA|NA BNPNBKBE_00986 1151292.QEW_3259 1.4e-57 229.9 Peptostreptococcaceae Bacteria 1U6KJ@1239,24AM0@186801,25T2P@186804,COG2369@1,COG2369@2 NA|NA|NA S Phage Mu protein F like protein BNPNBKBE_00989 1267600.JFGT01000005_gene2502 1.4e-36 158.3 Pantoea ko:K07497 ko00000 Bacteria 1MVXQ@1224,1RR4F@1236,3VZWT@53335,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain BNPNBKBE_00991 435842.HMPREF0848_01930 3.9e-66 257.3 Bacilli spxA_2 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1VYBB@1239,4HWYC@91061,COG1393@1,COG1393@2 NA|NA|NA P Belongs to the ArsC family BNPNBKBE_00992 1046629.Ssal_02111 6.8e-204 716.5 Bacilli recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 ko:K03553 ko03440,map03440 M00729 ko00000,ko00001,ko00002,ko03400 Bacteria 1TPD5@1239,4HAG5@91061,COG0468@1,COG0468@2 NA|NA|NA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage BNPNBKBE_00993 1046629.Ssal_02112 1.2e-225 788.9 Bacilli cinA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 1TQ1N@1239,4HATN@91061,COG1058@1,COG1058@2,COG1546@1,COG1546@2 NA|NA|NA S Belongs to the CinA family BNPNBKBE_00994 904306.HMPREF9192_0031 7.3e-103 379.8 Bacilli tag 3.2.2.20 ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V9B8@1239,4HJ4I@91061,COG2818@1,COG2818@2 NA|NA|NA L 3-methyladenine DNA glycosylase BNPNBKBE_00995 1046629.Ssal_02114 7.8e-103 379.8 Bacilli ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1V3KF@1239,4HHI5@91061,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB BNPNBKBE_00997 1046629.Ssal_02116 0.0 1229.2 Bacilli mutL GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TPGK@1239,4HB34@91061,COG0323@1,COG0323@2 NA|NA|NA L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex BNPNBKBE_00999 1046629.Ssal_02118 8.4e-70 269.6 Bacilli Bacteria 1VE2H@1239,4IPMG@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain BNPNBKBE_01000 1046629.Ssal_02119 1.2e-79 302.4 Bacilli Bacteria 1VHBQ@1239,2E0UI@1,32WBZ@2,4HRYH@91061 NA|NA|NA S Protein of unknown function (DUF3021) BNPNBKBE_01001 1046629.Ssal_02120 0.0 1619.8 Bacilli mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TPRJ@1239,4HA63@91061,COG0249@1,COG0249@2 NA|NA|NA L that it carries out the mismatch recognition step. This protein has a weak ATPase activity BNPNBKBE_01002 1046629.Ssal_02121 1.6e-55 221.9 Bacilli ymcA 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1V4W0@1239,4HH6Y@91061,COG4550@1,COG4550@2 NA|NA|NA S Belongs to the UPF0342 family BNPNBKBE_01003 1046629.Ssal_02122 6.9e-69 266.5 Bacilli argR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 ko:K03402 ko00000,ko03000 Bacteria 1V1R7@1239,4HFY8@91061,COG1438@1,COG1438@2 NA|NA|NA K Regulates arginine biosynthesis genes BNPNBKBE_01004 435842.HMPREF0848_01943 0.0 1109.4 Bacilli argS 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPEZ@1239,4HAR3@91061,COG0018@1,COG0018@2 NA|NA|NA J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA BNPNBKBE_01006 264199.stu0045 8.1e-246 855.9 Bacilli purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1095,iSB619.SA_RS09895 Bacteria 1TPMM@1239,4HACW@91061,COG0015@1,COG0015@2 NA|NA|NA F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily BNPNBKBE_01007 365659.smi_1095 3.6e-71 276.2 Bacilli Bacteria 1UQNK@1239,4HNVT@91061,COG4928@1,COG4928@2 NA|NA|NA S KAP family P-loop domain BNPNBKBE_01008 908612.HMPREF9720_0764 1.9e-15 90.1 Bacteria Bacteria COG1432@1,COG1432@2 NA|NA|NA S NYN domain BNPNBKBE_01009 904306.HMPREF9192_0016 2.5e-200 704.5 Bacilli purK 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQCD@1239,4H9M5@91061,COG0026@1,COG0026@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) BNPNBKBE_01010 904306.HMPREF9192_0015 2.6e-80 304.7 Bacilli purE GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551 Bacteria 1V1MV@1239,4HFR7@91061,COG0041@1,COG0041@2 NA|NA|NA F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) BNPNBKBE_01011 1046629.Ssal_02135 2.5e-239 834.3 Bacilli purD 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS05245,iYO844.BSU06530 Bacteria 1UHN9@1239,4HA70@91061,COG0151@1,COG0151@2 NA|NA|NA F Belongs to the GARS family BNPNBKBE_01012 1046629.Ssal_01740 7.8e-157 559.7 Bacilli ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1VUNU@1239,4HVY0@91061,COG3942@1,COG3942@2 NA|NA|NA S CHAP domain BNPNBKBE_01013 1046629.Ssal_02136 2.8e-293 1013.8 Bacilli purH GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.purH Bacteria 1TPQ5@1239,4H9YY@91061,COG0138@1,COG0138@2 NA|NA|NA F Bifunctional purine biosynthesis protein PurH BNPNBKBE_01014 1046629.Ssal_02137 2.2e-99 368.2 Bacilli purN 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3RJ@1239,4HGY5@91061,COG0299@1,COG0299@2 NA|NA|NA F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate BNPNBKBE_01015 435842.HMPREF0848_01955 2.5e-189 667.9 Bacilli purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 ko:K01933,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1844,iECSF_1327.ECSF_2340 Bacteria 1TP9J@1239,4HABW@91061,COG0150@1,COG0150@2 NA|NA|NA F Phosphoribosylformylglycinamidine cyclo-ligase BNPNBKBE_01016 1046629.Ssal_02139 2.4e-275 954.1 Bacilli purF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 iSB619.SA_RS05225 Bacteria 1TPH3@1239,4HAXU@91061,COG0034@1,COG0034@2 NA|NA|NA F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine BNPNBKBE_01017 1046629.Ssal_02140 0.0 2407.5 Bacilli purL 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAS@1239,4HB3N@91061,COG0046@1,COG0046@2,COG0047@1,COG0047@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL BNPNBKBE_01018 1046629.Ssal_02141 8.9e-130 469.5 Bacilli purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016881,GO:0044424,GO:0044444,GO:0044464 4.1.1.21,4.3.2.2,6.3.2.6 ko:K01587,ko:K01756,ko:K01923 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04209,R04559,R04591 RC00064,RC00162,RC00379,RC00444,RC00445,RC00590 ko00000,ko00001,ko00002,ko01000 iAF1260.b2476,iB21_1397.B21_02330,iBWG_1329.BWG_2240,iE2348C_1286.E2348C_2713,iEC042_1314.EC042_2677,iEC55989_1330.EC55989_2759,iECABU_c1320.ECABU_c27880,iECBD_1354.ECBD_1213,iECB_1328.ECB_02368,iECDH10B_1368.ECDH10B_2642,iECDH1ME8569_1439.ECDH1ME8569_2402,iECDH1ME8569_1439.EcDH1_1193,iECD_1391.ECD_02368,iECED1_1282.ECED1_2911,iECH74115_1262.ECH74115_3698,iECIAI1_1343.ECIAI1_2527,iECNA114_1301.ECNA114_2561,iECO103_1326.ECO103_2988,iECO111_1330.ECO111_3199,iECO26_1355.ECO26_3522,iECOK1_1307.ECOK1_2784,iECP_1309.ECP_2490,iECS88_1305.ECS88_2658,iECSE_1348.ECSE_2760,iECSF_1327.ECSF_2329,iECSP_1301.ECSP_3415,iECUMN_1333.ECUMN_2789,iECW_1372.ECW_m2698,iECs_1301.ECs3338,iEKO11_1354.EKO11_1259,iETEC_1333.ETEC_2581,iEcDH1_1363.EcDH1_1193,iEcE24377_1341.EcE24377A_2757,iEcHS_1320.EcHS_A2607,iEcSMS35_1347.EcSMS35_2623,iEcolC_1368.EcolC_1200,iG2583_1286.G2583_2999,iJN746.PP_1240,iJO1366.b2476,iJR904.b2476,iLF82_1304.LF82_1775,iNRG857_1313.NRG857_12360,iSFV_1184.SFV_2521,iSF_1195.SF2519,iSFxv_1172.SFxv_2773,iS_1188.S2669,iSbBS512_1146.SbBS512_E2848,iUMNK88_1353.UMNK88_3071,iWFL_1372.ECW_m2698,iY75_1357.Y75_RS12925,iYL1228.KPN_02810,iZ_1308.Z3735 Bacteria 1TP11@1239,4H9U8@91061,COG0152@1,COG0152@2 NA|NA|NA F Belongs to the SAICAR synthetase family BNPNBKBE_01019 1046629.Ssal_02142 8.1e-30 136.0 Bacteria acpP1 ko:K02078 ko00000,ko00001 Bacteria COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis BNPNBKBE_01020 1046629.Ssal_02143 9.2e-184 649.4 Bacilli plsX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPXS@1239,4HA0R@91061,COG0416@1,COG0416@2 NA|NA|NA I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA BNPNBKBE_01021 1046629.Ssal_02144 1e-139 502.7 Bacilli recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1UZ19@1239,4HAHI@91061,COG1381@1,COG1381@2 NA|NA|NA L Involved in DNA repair and RecF pathway recombination BNPNBKBE_01022 1046629.Ssal_02145 4.7e-216 756.9 Bacilli araT 2.6.1.1 ko:K00812,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00525 R00355,R00694,R00734,R00896,R02433,R02619,R04467,R05052 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase BNPNBKBE_01023 1046629.Ssal_02148 9.5e-175 619.4 Bacilli prs 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2848 Bacteria 1TQ6Q@1239,4HB61@91061,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) BNPNBKBE_01024 1046629.Ssal_02149 2.8e-85 322.8 Bacilli usp 3.5.1.28 ko:K21471,ko:K22409 ko00000,ko01000,ko01002,ko01011 CBM50 Bacteria 1VCXB@1239,4IS6H@91061,COG3883@1,COG3883@2,COG3942@1,COG3942@2 NA|NA|NA S CHAP domain BNPNBKBE_01025 1046629.Ssal_02150 5.1e-82 310.5 Bacilli mreD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 ko:K03571 ko00000,ko03036 9.B.157.1 Bacteria 1VEN7@1239,4HNAD@91061,COG2891@1,COG2891@2 NA|NA|NA M rod shape-determining protein MreD BNPNBKBE_01026 322159.STER_0040 1.3e-119 436.0 Bacilli mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 ko:K03570 ko00000,ko03036 9.B.157.1 Bacteria 1TR1V@1239,4HB0K@91061,COG1792@1,COG1792@2 NA|NA|NA M Involved in formation and maintenance of cell shape BNPNBKBE_01031 1046629.Ssal_00210 1.6e-49 201.8 Bacteria bta 1.8.1.8 ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Bacteria COG0526@1,COG0526@2 NA|NA|NA CO cell redox homeostasis BNPNBKBE_01032 435842.HMPREF0848_01462 6.3e-59 233.4 Bacilli ko:K07107 ko00000,ko01000 Bacteria 1VAGM@1239,4HIVC@91061,COG0824@1,COG0824@2 NA|NA|NA L thioesterase BNPNBKBE_01033 1046629.Ssal_00214 5.6e-141 506.9 Bacilli Bacteria 1TQSZ@1239,4HCXD@91061,COG2110@1,COG2110@2 NA|NA|NA S Macro domain protein BNPNBKBE_01034 904306.HMPREF9192_0562 5.3e-50 203.4 Bacilli trxA ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1VA3Y@1239,4HKKX@91061,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family BNPNBKBE_01035 1046629.Ssal_00216 1.7e-70 271.9 Bacilli yccU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06929 ko00000 Bacteria 1V7C7@1239,4HIZT@91061,COG1832@1,COG1832@2 NA|NA|NA S CoA-binding protein BNPNBKBE_01036 1046629.Ssal_00217 1e-142 512.7 Bacilli tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 ko:K03424 ko00000,ko01000 Bacteria 1TNY1@1239,4HA74@91061,COG0084@1,COG0084@2 NA|NA|NA L Hydrolase, tatd BNPNBKBE_01037 1046629.Ssal_00218 3.2e-98 364.4 Bacilli rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985,ko:K07476 ko00000,ko01000 Bacteria 1V3K3@1239,4HH5Y@91061,COG1658@1,COG1658@2 NA|NA|NA J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step BNPNBKBE_01038 1046629.Ssal_00219 3.5e-152 544.3 Bacilli ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 R10716 RC00003,RC03257 ko00000,ko01000,ko03009 Bacteria 1TP9W@1239,4HA4R@91061,COG0030@1,COG0030@2 NA|NA|NA J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits BNPNBKBE_01040 1046629.Ssal_00220 4.1e-161 573.9 Bacilli rsgA 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 Bacteria 1TPSQ@1239,4HA9W@91061,COG1162@1,COG1162@2 NA|NA|NA G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit BNPNBKBE_01041 904306.HMPREF9192_0569 1e-119 436.0 Bacilli rpe 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQK8@1239,4H9RW@91061,COG0036@1,COG0036@2 NA|NA|NA G Belongs to the ribulose-phosphate 3-epimerase family BNPNBKBE_01042 1046629.Ssal_00222 4e-113 414.1 Bacilli thiN 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 R00619 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1VA0W@1239,4HHS1@91061,COG1564@1,COG1564@2 NA|NA|NA H thiamine pyrophosphokinase BNPNBKBE_01043 1046629.Ssal_00223 7.9e-169 600.1 Bacilli rmuC ko:K09760 ko00000 Bacteria 1TPWI@1239,4HE2N@91061,COG1322@1,COG1322@2 NA|NA|NA S RmuC domain protein BNPNBKBE_01044 1046629.Ssal_00224 1.7e-176 625.2 Bacilli cbf ko:K03698 ko00000,ko01000,ko03019 Bacteria 1TPIU@1239,4HB1M@91061,COG3481@1,COG3481@2 NA|NA|NA S 3'-5' exoribonuclease yhaM BNPNBKBE_01045 904306.HMPREF9192_0573 4e-142 510.8 Bacilli purR 2.4.2.7 ko:K00759,ko:K09685 ko00230,ko01100,map00230,map01100 R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko03000,ko04147 Bacteria 1TPN9@1239,4HB8I@91061,COG0503@1,COG0503@2 NA|NA|NA F operon repressor BNPNBKBE_01046 1046629.Ssal_00226 2.3e-69 268.1 Bacilli rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02950 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1FJ@1239,4HFMZ@91061,COG0048@1,COG0048@2 NA|NA|NA J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit BNPNBKBE_01047 1046629.Ssal_00227 3.9e-81 307.4 Bacilli rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02992 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1GG@1239,4H9PA@91061,COG0049@1,COG0049@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA BNPNBKBE_01048 1046629.Ssal_00229 0.0 1363.2 Bacilli fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02355 ko00000,ko03012,ko03029 Bacteria 1TPF9@1239,4HAB8@91061,COG0480@1,COG0480@2 NA|NA|NA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome BNPNBKBE_01049 1005705.HMPREF9967_0458 7.1e-181 639.8 Streptococcus infantis gap GO:0000166,GO:0002020,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009986,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0019899,GO:0022610,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044464,GO:0044650,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:0140030,GO:0140032,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1TNYU@1239,43FFT@68892,4H9NS@91061,COG0057@1,COG0057@2 NA|NA|NA C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain BNPNBKBE_01050 1046629.Ssal_00231 1.4e-114 419.1 Firmicutes Bacteria 1V2YR@1239,28KD0@1,2Z9ZS@2 NA|NA|NA BNPNBKBE_01051 1046629.Ssal_00232 1.7e-221 775.0 Bacilli pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iSB619.SA_RS04145 Bacteria 1TP3H@1239,4H9R3@91061,COG0126@1,COG0126@2 NA|NA|NA F Belongs to the phosphoglycerate kinase family BNPNBKBE_01052 1046629.Ssal_00233 9.6e-86 322.8 Bacilli Bacteria 1VAJG@1239,4HKDZ@91061,COG4129@1,COG4129@2 NA|NA|NA S Fusaric acid resistance protein-like BNPNBKBE_01053 435842.HMPREF0848_01442 8.5e-63 246.1 Bacilli glnR GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141 ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1V6JE@1239,4HKM6@91061,COG0789@1,COG0789@2 NA|NA|NA K Transcriptional regulator BNPNBKBE_01054 1046629.Ssal_00235 2e-263 914.4 Bacilli glnA 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 1TNZA@1239,4HACE@91061,COG0174@1,COG0174@2 NA|NA|NA E glutamine synthetase BNPNBKBE_01055 435842.HMPREF0848_01440 1.5e-115 422.2 Bacilli pscB Bacteria 1V8WM@1239,4HIMT@91061,COG3942@1,COG3942@2 NA|NA|NA M CHAP domain protein BNPNBKBE_01056 435842.HMPREF0848_01439 0.0 1114.0 Bacilli rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TQ9G@1239,4HAAP@91061,COG0595@1,COG0595@2 NA|NA|NA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay BNPNBKBE_01057 1046629.Ssal_00239 1.5e-33 148.3 Bacilli ykzG Bacteria 1VEI7@1239,4HNSK@91061,COG5503@1,COG5503@2 NA|NA|NA S Belongs to the UPF0356 family BNPNBKBE_01058 1046629.Ssal_00240 1.5e-118 432.2 Bacilli yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03016 Bacteria 1V4YX@1239,4HHD7@91061,COG1214@1,COG1214@2 NA|NA|NA O COG1214, inactive homolog of metal-dependent proteases BNPNBKBE_01059 264199.stu1771 9e-72 276.2 Bacilli rimI 2.3.1.128 ko:K03789 ko00000,ko01000,ko03009 Bacteria 1V6KU@1239,4HP50@91061,COG0454@1,COG0456@2 NA|NA|NA K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 BNPNBKBE_01060 1046629.Ssal_00242 1.6e-185 655.2 Bacilli tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1TQDR@1239,4HANB@91061,COG0533@1,COG0533@2 NA|NA|NA O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction BNPNBKBE_01061 435842.HMPREF0848_01434 1.4e-111 409.1 Bacilli azlC Bacteria 1V64T@1239,4HH44@91061,COG1296@1,COG1296@2 NA|NA|NA E AzlC protein BNPNBKBE_01062 435842.HMPREF0848_01433 2.2e-46 191.4 Bacilli azlD Bacteria 1VH9Q@1239,4HRBI@91061,COG4392@1,COG4392@2 NA|NA|NA S branched-chain amino acid BNPNBKBE_01063 1046629.Ssal_00246 0.0 1593.2 Bacilli recD2 3.1.11.5 ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPZH@1239,4HATQ@91061,COG0507@1,COG0507@2 NA|NA|NA L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity BNPNBKBE_01064 904306.HMPREF9192_0591 4e-113 414.1 Bacilli lepB 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1V7H9@1239,4HMGQ@91061,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family BNPNBKBE_01065 1046629.Ssal_00249 2.9e-154 551.2 Bacilli rnhC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470,ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1TQBE@1239,4H9QR@91061,COG1039@1,COG1039@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids BNPNBKBE_01066 1302863.I872_01550 1.4e-26 125.6 Bacilli zapA GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047 ko:K09888 ko00000,ko03036 Bacteria 1VFZS@1239,4HP4T@91061,COG3027@1,COG3027@2 NA|NA|NA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division BNPNBKBE_01067 322159.STER_1738 9.1e-90 336.3 Bacteria cvpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 ko:K03558 ko00000 Bacteria COG1286@1,COG1286@2 NA|NA|NA S toxin biosynthetic process BNPNBKBE_01068 435842.HMPREF0848_01427 0.0 1480.7 Bacilli mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TP5W@1239,4H9NZ@91061,COG1193@1,COG1193@2 NA|NA|NA L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity BNPNBKBE_01069 904306.HMPREF9192_0604 0.0 1683.3 Bacilli polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1TPKJ@1239,4H9S7@91061,COG0258@1,COG0258@2,COG0749@1,COG0749@2 NA|NA|NA L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity BNPNBKBE_01071 585204.SMSK597_1021 2.9e-09 67.8 Streptococcus mitis Bacteria 1U4B0@1239,2DKAS@1,2TP5R@28037,30920@2,4IE2N@91061 NA|NA|NA BNPNBKBE_01073 1046629.Ssal_00266 1.1e-222 778.9 Bacilli mutY ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPUT@1239,4H9UM@91061,COG1194@1,COG1194@2 NA|NA|NA L A G-specific adenine glycosylase BNPNBKBE_01074 1045856.EcWSU1_02642 1.9e-175 621.7 Enterobacter prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iLJ478.TM1628,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665 Bacteria 1MW21@1224,1RMUC@1236,3X1WF@547,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) BNPNBKBE_01075 1005994.GTGU_03757 9.2e-62 243.0 Gammaproteobacteria rpoC GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03046,ko:K13797 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1MU3M@1224,1RPYH@1236,COG0086@1,COG0086@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates BNPNBKBE_01076 435842.HMPREF0848_00168 1.2e-29 135.2 Bacilli agrA ko:K07707 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko02022 Bacteria 1V392@1239,4HHAI@91061,COG3279@1,COG3279@2 NA|NA|NA KT Response regulator of the LytR AlgR family BNPNBKBE_01077 904306.HMPREF9192_0893 4.4e-247 860.1 Bacilli obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043021,GO:0043022,GO:0043167,GO:0043168,GO:0043934,GO:0044424,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03979 ko00000,ko01000,ko03009 Bacteria 1TPX7@1239,4H9P8@91061,COG0536@1,COG0536@2 NA|NA|NA S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BNPNBKBE_01079 1046629.Ssal_00568 4.7e-126 457.2 Bacilli rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 ko00000,ko01000,ko03009 Bacteria 1TQZ2@1239,4H9VU@91061,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family BNPNBKBE_01080 1141106.CAIB01000144_gene1221 3.4e-10 72.8 Bacilli Bacteria 1V7HC@1239,4HVUS@91061,COG1397@1,COG1397@2 NA|NA|NA O ADP-ribosylglycohydrolase BNPNBKBE_01081 264199.stu1516 7.4e-62 243.0 Bacilli paaI ko:K02614 ko00360,map00360 R09840 RC00004,RC00014 ko00000,ko00001,ko01000 Bacteria 1VN0K@1239,4HM66@91061,COG2050@1,COG2050@2 NA|NA|NA Q protein possibly involved in aromatic compounds catabolism BNPNBKBE_01082 1046629.Ssal_00565 3.5e-61 240.7 Bacteria ycaO ko:K06889,ko:K07397,ko:K09136 ko00000,ko03009 Bacteria COG1765@1,COG1765@2 NA|NA|NA O OsmC-like protein BNPNBKBE_01084 1046629.Ssal_00562 1.4e-151 542.3 Firmicutes Bacteria 1TYSF@1239,COG0697@1,COG0697@2 NA|NA|NA EG Permeases of the drug metabolite transporter (DMT) superfamily BNPNBKBE_01085 1123300.AUIN01000016_gene627 3.2e-07 60.8 Bacteria Bacteria COG1598@1,COG1598@2 NA|NA|NA N PFAM Uncharacterised protein family UPF0150 BNPNBKBE_01086 1046629.Ssal_00560 2.9e-111 407.9 Bacilli serB 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 Bacteria 1V9R7@1239,4HTNE@91061,COG0560@1,COG0560@2 NA|NA|NA E phosphoserine phosphatase BNPNBKBE_01087 1046629.Ssal_00559 3.2e-298 1030.4 Bacilli ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 ko:K06286,ko:K07158 ko00000,ko03036 Bacteria 1TQR7@1239,4HA15@91061,COG4477@1,COG4477@2 NA|NA|NA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization BNPNBKBE_01088 1046629.Ssal_00558 0.0 1276.2 Bacilli gyrB GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02470,ko:K02622 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TQ0R@1239,4H9Y6@91061,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner BNPNBKBE_01089 1046629.Ssal_00557 1.2e-97 362.5 Bacilli 3.1.3.18 ko:K01091,ko:K07025 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1V421@1239,4HHYH@91061,COG0546@1,COG0546@2 NA|NA|NA S IA, variant 1 BNPNBKBE_01090 904306.HMPREF9192_0878 1.6e-115 422.2 Firmicutes lrgB Bacteria 1TRGN@1239,COG1346@1,COG1346@2 NA|NA|NA M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses BNPNBKBE_01091 435842.HMPREF0848_01131 5.9e-56 223.4 Firmicutes lrgA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06518 ko00000,ko02000 1.E.14.2 Bacteria 1VEN4@1239,COG1380@1,COG1380@2 NA|NA|NA S Effector of murein hydrolase LrgA BNPNBKBE_01093 1046629.Ssal_01688 5.4e-59 233.4 Bacilli arsC 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1VA5Q@1239,4HKQQ@91061,COG1393@1,COG1393@2 NA|NA|NA P Belongs to the ArsC family BNPNBKBE_01094 904306.HMPREF9192_0874 9.2e-73 279.6 Bacteria ogt GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63,3.2.2.20 ko:K00567,ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria COG0350@1,COG0350@2 NA|NA|NA L methylated-DNA-[protein]-cysteine S-methyltransferase activity BNPNBKBE_01095 1046629.Ssal_00539 4.5e-219 766.9 Bacilli serA 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1V410@1239,4H9PH@91061,COG0111@1,COG0111@2 NA|NA|NA EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family BNPNBKBE_01096 904306.HMPREF9192_0872 1.1e-101 375.9 Bacilli wecD Bacteria 1UIW7@1239,4ISU9@91061,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase (GNAT) domain BNPNBKBE_01097 1046629.Ssal_00537 1.5e-208 731.9 Bacilli serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP6Y@1239,4HATT@91061,COG1932@1,COG1932@2 NA|NA|NA E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine BNPNBKBE_01098 1046629.Ssal_00536 7.3e-153 546.6 Bacilli Bacteria 1TRQ7@1239,4HE30@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family BNPNBKBE_01099 904306.HMPREF9192_0869 2e-70 271.6 Bacilli gloA 4.4.1.5 ko:K01759,ko:K15772 ko00620,ko02010,map00620,map02010 M00491 R02530 RC00004,RC00740 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1.16,3.A.1.1.2 Bacteria 1V6K3@1239,4HJ7X@91061,COG0346@1,COG0346@2 NA|NA|NA E Lactoylglutathione lyase BNPNBKBE_01100 904306.HMPREF9192_0867 1.9e-145 521.9 Bacilli XK27_08050 Bacteria 1TPXU@1239,4HGRC@91061,COG0330@1,COG0330@2 NA|NA|NA O HflC and HflK could regulate a protease BNPNBKBE_01101 904306.HMPREF9192_0865 7e-203 713.0 Bacilli potD ko:K11069 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 iSB619.SA_RS05395 Bacteria 1TPY1@1239,4HAET@91061,COG0687@1,COG0687@2 NA|NA|NA P spermidine putrescine ABC transporter BNPNBKBE_01102 322159.STER_1494 2.3e-131 474.9 Bacilli potC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008519,GO:0015075,GO:0015101,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015595,GO:0015606,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072488,GO:0098533,GO:0098655,GO:0098796,GO:0098797,GO:1902047,GO:1902494,GO:1902495,GO:1903711,GO:1904949,GO:1990351 ko:K11070 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 iSBO_1134.SBO_1939 Bacteria 1V0VD@1239,4H9ZC@91061,COG1177@1,COG1177@2 NA|NA|NA P ABC-type spermidine putrescine transport system, permease component II BNPNBKBE_01103 435842.HMPREF0848_01147 1.5e-138 498.8 Bacilli potB ko:K11071 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 Bacteria 1TQ7Z@1239,4HAYS@91061,COG1176@1,COG1176@2 NA|NA|NA P ABC-type spermidine putrescine transport system, permease component I BNPNBKBE_01104 904306.HMPREF9192_0862 5.2e-212 743.4 Bacilli potA 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 iSB619.SA_RS05380 Bacteria 1TP2M@1239,4H9MS@91061,COG3842@1,COG3842@2 NA|NA|NA P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system BNPNBKBE_01105 1046629.Ssal_00526 5.8e-166 590.1 Bacilli murB 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 Bacteria 1TP3W@1239,4HAD8@91061,COG0812@1,COG0812@2 NA|NA|NA M cell wall formation BNPNBKBE_01106 1046629.Ssal_00525 6.1e-77 293.5 Bacilli folK 2.7.6.3,4.1.2.25 ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503,R03504 RC00002,RC00017,RC00721,RC00943 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6PR@1239,4HIMG@91061,COG0801@1,COG0801@2 NA|NA|NA H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BNPNBKBE_01107 1046629.Ssal_00524 1.4e-59 235.3 Bacilli folB 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01633,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503,R03504,R11037,R11073 RC00002,RC00017,RC00121,RC00721,RC00842,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 1VA0I@1239,4HKKK@91061,COG1539@1,COG1539@2 NA|NA|NA H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin BNPNBKBE_01108 435842.HMPREF0848_01152 9.9e-293 1011.9 Bacilli amy 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 R02108,R02112,R11262 ko00000,ko00001,ko01000 GH13 Bacteria 1TRKZ@1239,4HC8C@91061,COG0366@1,COG0366@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family BNPNBKBE_01109 1046629.Ssal_00522 1.5e-144 518.8 Bacilli folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15,2.7.6.3 ko:K00796,ko:K13941 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503 RC00002,RC00017,RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS03115 Bacteria 1TPKT@1239,4H9SY@91061,COG0294@1,COG0294@2 NA|NA|NA H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives BNPNBKBE_01110 1046629.Ssal_00521 2.2e-99 368.2 Bacilli folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv3609c Bacteria 1TRNM@1239,4HAXS@91061,COG0302@1,COG0302@2 NA|NA|NA F gtp cyclohydrolase BNPNBKBE_01111 1046629.Ssal_00520 0.0 1168.7 Bacilli ydaO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 Bacteria 1TQE1@1239,4HAZH@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid BNPNBKBE_01112 1046629.Ssal_00519 1.1e-231 808.9 Bacilli folC 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0166 Bacteria 1TPX5@1239,4HBJM@91061,COG0285@1,COG0285@2 NA|NA|NA H Belongs to the folylpolyglutamate synthase family BNPNBKBE_01113 1046629.Ssal_00518 1.5e-36 158.3 Bacteria ylqC ko:K06960 ko00000 Bacteria COG1837@1,COG1837@2 NA|NA|NA L Belongs to the UPF0109 family BNPNBKBE_01114 1046629.Ssal_00517 2.4e-43 181.0 Bacilli rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VA0X@1239,4HKNN@91061,COG0228@1,COG0228@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS16 family BNPNBKBE_01116 435842.HMPREF0848_01160 8.7e-211 739.6 Bacteria 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria COG3290@1,COG3290@2 NA|NA|NA T protein histidine kinase activity BNPNBKBE_01117 1046629.Ssal_00514 2.2e-123 448.4 Bacteria agrA ko:K07707 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko02022 Bacteria COG3279@1,COG3279@2 NA|NA|NA KT phosphorelay signal transduction system BNPNBKBE_01118 1046629.Ssal_02044 3.9e-87 327.4 Bacteria sigH ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation BNPNBKBE_01119 1046629.Ssal_02043 2.3e-134 485.0 Bacilli ykuT GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0042802,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 ko:K22044 ko00000,ko02000 1.A.23.3 Bacteria 1TR9Z@1239,4HCB8@91061,COG0668@1,COG0668@2 NA|NA|NA M mechanosensitive ion channel BNPNBKBE_01120 1046629.Ssal_02041 5.8e-228 796.6 Bacilli tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K03545 ko00000 Bacteria 1TQQ8@1239,4H9Q8@91061,COG0544@1,COG0544@2 NA|NA|NA D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase BNPNBKBE_01121 1046629.Ssal_02039 1.3e-70 272.7 Bacilli rpoE GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Bacteria 1V6WX@1239,4HIUK@91061,COG3343@1,COG3343@2 NA|NA|NA K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling BNPNBKBE_01122 1046629.Ssal_02036 2.9e-309 1067.0 Bacilli pyrG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS01075,iNJ661.Rv1699 Bacteria 1TP34@1239,4H9X6@91061,COG0504@1,COG0504@2 NA|NA|NA F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates BNPNBKBE_01123 1046629.Ssal_02035 8.4e-84 316.2 Bacilli XK27_03960 Bacteria 1VFZQ@1239,2E0MY@1,32W75@2,4HKWR@91061 NA|NA|NA S Protein of unknown function (DUF3013) BNPNBKBE_01124 1046629.Ssal_02034 7.8e-76 289.7 Bacilli mutT3 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 1V8D5@1239,4HJKW@91061,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain BNPNBKBE_01125 1046629.Ssal_02033 1.3e-57 228.8 Bacilli XK27_02675 Bacteria 1VCQJ@1239,4HN13@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase GNAT Family BNPNBKBE_01126 861455.HMPREF9184_00690 8.9e-14 81.6 Bacilli XK27_02675 Bacteria 1VCQJ@1239,4HN13@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase GNAT Family BNPNBKBE_01127 1046629.Ssal_02032 3.5e-177 627.5 Bacilli prmA ko:K02687 ko00000,ko01000,ko03009 Bacteria 1TPKI@1239,4HAMF@91061,COG2264@1,COG2264@2 NA|NA|NA J Ribosomal protein L11 methyltransferase BNPNBKBE_01128 1046629.Ssal_02031 7.7e-132 476.5 Bacilli rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 ko00000,ko01000,ko03009 Bacteria 1V1CT@1239,4HH8P@91061,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit BNPNBKBE_01129 435842.HMPREF0848_01474 0.0 1440.2 Bacilli cpdB GO:0003674,GO:0003824,GO:0004112,GO:0005575,GO:0005623,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008252,GO:0008254,GO:0008663,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0042597,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.1.3.6,3.1.4.16 ko:K01119 ko00230,ko00240,map00230,map00240 R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135 RC00078,RC00296 ko00000,ko00001,ko01000 iEC55989_1330.EC55989_4773,iECH74115_1262.ECH74115_5730,iECNA114_1301.ECNA114_4436,iECSP_1301.ECSP_5315,iECW_1372.ECW_m4577,iECs_1301.ECs5191,iEKO11_1354.EKO11_4095,iEcE24377_1341.EcE24377A_4783,iG2583_1286.G2583_5043,iWFL_1372.ECW_m4577,iZ_1308.Z5824 Bacteria 1TPV2@1239,4HB9S@91061,COG0737@1,COG0737@2 NA|NA|NA F Belongs to the 5'-nucleotidase family BNPNBKBE_01130 1046629.Ssal_02029 9.1e-83 312.8 Bacilli nrdI ko:K03647 ko00000 Bacteria 1V71V@1239,4HIW7@91061,COG1780@1,COG1780@2 NA|NA|NA F Belongs to the NrdI family BNPNBKBE_01131 1046629.Ssal_02028 0.0 1433.3 Bacilli relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 iHN637.CLJU_RS16615,iYO844.BSU27600 Bacteria 1TNYZ@1239,4HBX7@91061,COG0317@1,COG0317@2 NA|NA|NA KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance BNPNBKBE_01132 1046629.Ssal_02026 2.4e-72 278.1 Bacilli dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K07560 ko00000,ko01000,ko03016 Bacteria 1V6GH@1239,4HINN@91061,COG1490@1,COG1490@2 NA|NA|NA J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality BNPNBKBE_01133 1046629.Ssal_02025 0.0 1637.1 Bacilli dex 3.2.1.11 ko:K05988 ko00500,map00500 R11309 ko00000,ko00001,ko01000 GH66 Bacteria 1TS2G@1239,4HF5J@91061,COG5297@1,COG5297@2 NA|NA|NA G Glycosyl hydrolase family 66 BNPNBKBE_01134 1046629.Ssal_02023 7.3e-236 822.8 Bacilli ilvA GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP22@1239,4H9NK@91061,COG1171@1,COG1171@2 NA|NA|NA E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA BNPNBKBE_01135 904306.HMPREF9192_0243 1.9e-112 411.8 Bacilli def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 ko:K01450,ko:K01462 ko00270,ko00630,map00270,map00630 R00653 RC00165,RC00323 ko00000,ko00001,ko01000 Bacteria 1V5C6@1239,4HGUI@91061,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions BNPNBKBE_01136 1046629.Ssal_02021 1.1e-102 379.4 Bacilli fnr5 Bacteria 1V2AH@1239,4HFNC@91061,COG0664@1,COG0664@2 NA|NA|NA K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases BNPNBKBE_01137 1046629.Ssal_02020 7.4e-182 643.3 Bacilli yhjX ko:K03449,ko:K08177 ko00000,ko02000 2.A.1.11,2.A.1.17 Bacteria 1TSM5@1239,4HF98@91061,COG2807@1,COG2807@2 NA|NA|NA P Major Facilitator BNPNBKBE_01138 435842.HMPREF0848_01487 5.4e-43 179.9 Bacilli rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VA5C@1239,4HKE9@91061,COG0184@1,COG0184@2 NA|NA|NA J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome BNPNBKBE_01139 1046629.Ssal_02018 4.4e-82 310.8 Bacilli Bacteria 1VM0K@1239,4HVBZ@91061,COG4767@1,COG4767@2 NA|NA|NA V VanZ like family BNPNBKBE_01140 1046629.Ssal_02017 1.8e-180 639.8 Bacilli Bacteria 1VXI0@1239,4HMHC@91061,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation BNPNBKBE_01141 904306.HMPREF9192_0239 2.2e-123 448.4 Bacilli glnQ ko:K17074,ko:K17076 ko02010,map02010 M00589 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.20 Bacteria 1TNYD@1239,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E abc transporter atp-binding protein BNPNBKBE_01142 1046629.Ssal_02015 4.3e-270 936.8 Bacilli glnP ko:K02029,ko:K02030,ko:K10040,ko:K17073,ko:K17074 ko02010,map02010 M00228,M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1TPM3@1239,4HAS2@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2 NA|NA|NA P ABC transporter BNPNBKBE_01143 1046629.Ssal_02014 1.5e-152 545.4 Bacilli uppP GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031224,GO:0031226,GO:0042221,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050380,GO:0050896,GO:0071944 3.6.1.27 ko:K06153 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 iYL1228.KPN_03461 Bacteria 1TPFA@1239,4HB0M@91061,COG1968@1,COG1968@2 NA|NA|NA V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin BNPNBKBE_01144 1118055.CAGU01000052_gene1831 4.1e-17 94.4 Firmicutes Bacteria 1VDXT@1239,2E7YQ@1,332D4@2 NA|NA|NA S Protein of unknown function (DUF3021) BNPNBKBE_01145 1046629.Ssal_02012 1e-123 449.5 Bacilli mecA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K16511 ko00000 Bacteria 1UZ7D@1239,4HID6@91061,COG4862@1,COG4862@2 NA|NA|NA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis BNPNBKBE_01146 1046629.Ssal_02011 7.4e-182 643.3 Bacilli tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 ko:K02851 R08856 RC00002 ko00000,ko01000,ko01003,ko01005 Bacteria 1TP9V@1239,4H9KT@91061,COG0472@1,COG0472@2 NA|NA|NA M transferase BNPNBKBE_01147 1046629.Ssal_02010 1.7e-137 495.4 Bacilli sufC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 ko:K09013 ko00000,ko02000 iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710 Bacteria 1TQ98@1239,4HAD9@91061,COG0396@1,COG0396@2 NA|NA|NA O ABC-type transport system involved in Fe-S cluster assembly, ATPase component BNPNBKBE_01148 904306.HMPREF9192_0233 6.9e-234 816.2 Bacilli sufD ko:K07033,ko:K09015 ko00000 Bacteria 1TRT0@1239,4HB6W@91061,COG0719@1,COG0719@2 NA|NA|NA O assembly protein SufD BNPNBKBE_01149 1046629.Ssal_02008 1e-237 828.9 Bacilli sufS 2.8.1.7,4.4.1.16 ko:K04487,ko:K11717 ko00450,ko00730,ko01100,ko04122,map00450,map00730,map01100,map04122 R03599,R07460,R11528,R11529 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TQ1W@1239,4HA6Z@91061,COG0520@1,COG0520@2 NA|NA|NA E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine BNPNBKBE_01150 904306.HMPREF9192_0231 9.4e-74 282.7 Bacilli nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 ko:K04488 ko00000 Bacteria 1V3H9@1239,4HIJ0@91061,COG0822@1,COG0822@2 NA|NA|NA C SUF system FeS assembly protein, NifU family BNPNBKBE_01151 904306.HMPREF9192_0230 2.9e-273 947.2 Bacilli sufB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 ko:K07033,ko:K09014 ko00000 Bacteria 1TQ21@1239,4HA1Z@91061,COG0719@1,COG0719@2 NA|NA|NA O assembly protein SufB BNPNBKBE_01152 1123311.KB904471_gene1168 4.7e-26 124.0 Bacilli Bacteria 1W24H@1239,2DCPN@1,2ZEV1@2,4HZKX@91061 NA|NA|NA BNPNBKBE_01153 1046629.Ssal_01995 1.8e-156 558.5 Bacilli hslO GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008 ko:K04083 ko00000,ko03110 Bacteria 1TRCH@1239,4HAFR@91061,COG1281@1,COG1281@2 NA|NA|NA O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress BNPNBKBE_01154 435842.HMPREF0848_01508 2.8e-182 644.4 Bacilli dus ko:K05540 ko00000,ko01000,ko03016 Bacteria 1TQ2R@1239,4HA9K@91061,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines BNPNBKBE_01155 1046629.Ssal_01993 1e-70 272.7 Bacilli adcR Bacteria 1VXZT@1239,4HXMU@91061,COG1846@1,COG1846@2 NA|NA|NA K transcriptional BNPNBKBE_01156 904306.HMPREF9192_0224 7.1e-135 486.5 Bacilli adcC ko:K09817 ko02010,map02010 M00242 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15.3,3.A.1.15.5 iHN637.CLJU_RS15665,iYO844.BSU02860 Bacteria 1TQ68@1239,4HAZI@91061,COG1121@1,COG1121@2 NA|NA|NA P ABC transporter, ATP-binding protein BNPNBKBE_01157 904306.HMPREF9192_0223 1.9e-128 465.3 Bacilli adcB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 ko:K09816 ko02010,map02010 M00242 ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 Bacteria 1TR79@1239,4HC3C@91061,COG1108@1,COG1108@2 NA|NA|NA P ABC transporter (Permease BNPNBKBE_01158 435842.HMPREF0848_01512 5.5e-159 567.0 Bacilli mleP2 ko:K07088 ko00000 Bacteria 1UY4N@1239,4HB48@91061,COG0679@1,COG0679@2 NA|NA|NA S Transporter, auxin efflux carrier (AEC) family protein BNPNBKBE_01159 1046629.Ssal_01989 0.0 1340.5 Bacilli ptsG 2.7.1.199,2.7.1.201,2.7.1.208,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02778,ko:K02779,ko:K02808,ko:K02809,ko:K02810,ko:K02817,ko:K02818,ko:K02819,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00269,M00270,M00271,M00272,M00303,M00806 R00811,R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.13,4.A.1.2.2,4.A.1.2.4,4.A.1.2.5,4.A.1.2.6,4.A.1.2.8,4.A.1.2.9 Bacteria 1TPJ8@1239,4HA8X@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G pts system BNPNBKBE_01160 1046629.Ssal_01988 3.1e-158 564.3 Bacilli rgfB 3.1.3.90 ko:K06896 ko00500,map00500 R10486 RC00017 ko00000,ko00001,ko01000 Bacteria 1TQZG@1239,4HGS5@91061,COG3568@1,COG3568@2 NA|NA|NA L Endonuclease/Exonuclease/phosphatase family BNPNBKBE_01161 1046629.Ssal_01987 1.6e-257 894.8 Bacilli pgi GO:0003674,GO:0003824,GO:0004347,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 iLJ478.TM1385 Bacteria 1TP29@1239,4H9VI@91061,COG0166@1,COG0166@2 NA|NA|NA G Belongs to the GPI family BNPNBKBE_01162 1046629.Ssal_01986 1.4e-148 532.3 Bacteria Z012_04635 ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria COG1396@1,COG1396@2 NA|NA|NA K sequence-specific DNA binding BNPNBKBE_01163 1046629.Ssal_01985 1.6e-272 944.9 Bacilli ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TSRV@1239,4HCIZ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter BNPNBKBE_01164 1046629.Ssal_01984 6.1e-126 456.8 Bacilli yeeN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 Bacteria 1TPP5@1239,4H9WJ@91061,COG0217@1,COG0217@2 NA|NA|NA K transcriptional regulatory protein BNPNBKBE_01165 904306.HMPREF9192_0217 9.1e-48 196.1 Bacteria yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria COG1862@1,COG1862@2 NA|NA|NA U protein transport BNPNBKBE_01166 1046629.Ssal_01982 9.1e-141 506.1 Bacilli uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 Bacteria 1TQTS@1239,4HA37@91061,COG0020@1,COG0020@2 NA|NA|NA H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids BNPNBKBE_01167 1046629.Ssal_01981 1.3e-142 512.3 Bacilli cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS06255 Bacteria 1TT0Q@1239,4HAMN@91061,COG4589@1,COG4589@2 NA|NA|NA S Belongs to the CDS family BNPNBKBE_01168 1046629.Ssal_01980 6.1e-230 803.1 Bacilli rseP GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107,3.4.21.116 ko:K04771,ko:K06399,ko:K11749,ko:K16922 ko01503,ko02020,ko02024,ko04112,map01503,map02020,map02024,map04112 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1TPMC@1239,4HAQ5@91061,COG0750@1,COG0750@2 NA|NA|NA M zinc metalloprotease BNPNBKBE_01169 1046629.Ssal_01979 0.0 1203.7 Bacilli proS GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iJN678.proS,iUTI89_1310.UTI89_C0210 Bacteria 1TRBV@1239,4H9NN@91061,COG0442@1,COG0442@2 NA|NA|NA J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS BNPNBKBE_01170 1046629.Ssal_01978 0.0 1101.3 Bacilli WQ51_06230 ko:K01989,ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPB0@1239,4HESK@91061,COG2984@1,COG2984@2,COG4120@1,COG4120@2 NA|NA|NA S ABC transporter BNPNBKBE_01171 1046629.Ssal_01977 1.4e-142 512.3 Bacilli cmpC ko:K05833 M00247 ko00000,ko00002,ko02000 Bacteria 1TPAN@1239,4HCHC@91061,COG1101@1,COG1101@2 NA|NA|NA S abc transporter atp-binding protein BNPNBKBE_01172 1046629.Ssal_01975 4.9e-42 176.8 Bacteria groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0032991,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:0101031,GO:1903506,GO:1990220,GO:2000112,GO:2001141 ko:K04078 ko00000,ko03029,ko03110 Bacteria COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter BNPNBKBE_01173 1046629.Ssal_01974 3.4e-286 990.3 Bacilli groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 1TP1T@1239,4HA38@91061,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions BNPNBKBE_01175 435842.HMPREF0848_01529 1.5e-44 185.3 Bacteria Bacteria 2C0H5@1,2ZRTJ@2 NA|NA|NA BNPNBKBE_01176 904306.HMPREF9192_0207 7.6e-55 219.5 Bacilli Bacteria 1VKEZ@1239,4HS74@91061,COG2314@1,COG2314@2 NA|NA|NA S TM2 domain BNPNBKBE_01177 1046629.Ssal_01970 3.5e-160 570.9 Bacilli rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 Bacteria 1TSM6@1239,4HA7M@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil BNPNBKBE_01178 904306.HMPREF9192_0205 0.0 1482.6 Bacilli pbp2A 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366,ko:K12555,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1TPM5@1239,4H9SA@91061,COG0744@1,COG0744@2 NA|NA|NA M penicillin-binding protein BNPNBKBE_01179 904306.HMPREF9192_0204 2.8e-24 117.1 Firmicutes secE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1W4QH@1239,COG0690@1,COG0690@2 NA|NA|NA U Belongs to the SecE SEC61-gamma family BNPNBKBE_01180 1046629.Ssal_01967 8.4e-96 356.3 Bacilli nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 1TR3P@1239,4HAJA@91061,COG0250@1,COG0250@2 NA|NA|NA K Participates in transcription elongation, termination and antitermination BNPNBKBE_01181 904306.HMPREF9192_0202 8e-68 263.1 Bacteria 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 R02029,R05627 RC00002,RC00017 ko00000,ko00001,ko01000,ko01011 Bacteria COG0671@1,COG0671@2 NA|NA|NA I phosphatidate phosphatase activity BNPNBKBE_01182 904306.HMPREF9192_0201 5.2e-142 510.4 Bacilli cof Bacteria 1TR16@1239,4HK1G@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase BNPNBKBE_01183 1046629.Ssal_01963 8.5e-134 483.0 Bacilli glcR ko:K02444,ko:K22103 ko00000,ko03000 Bacteria 1V6VV@1239,4HK1E@91061,COG1349@1,COG1349@2 NA|NA|NA K transcriptional regulator (DeoR family) BNPNBKBE_01184 435842.HMPREF0848_01539 0.0 1691.4 Bacilli leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TP0Y@1239,4HAG1@91061,COG0495@1,COG0495@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family BNPNBKBE_01185 1046629.Ssal_01960 1.2e-71 275.8 Bacilli Bacteria 1V1U2@1239,4HI88@91061,COG1846@1,COG1846@2 NA|NA|NA K transcriptional BNPNBKBE_01186 1046629.Ssal_01959 1.7e-224 785.0 Bacilli ko:K06889 ko00000 Bacteria 1V38K@1239,4HE7V@91061,COG1073@1,COG1073@2 NA|NA|NA S COG1073 Hydrolases of the alpha beta superfamily BNPNBKBE_01187 904306.HMPREF9192_0196 1.2e-36 159.5 Bacilli yjdF Bacteria 1V2J3@1239,28NY7@1,2ZBVG@2,4HMY0@91061 NA|NA|NA S Protein of unknown function (DUF2992) BNPNBKBE_01188 435842.HMPREF0848_01541 2.2e-45 188.0 Bacteria 3.2.2.21 ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria COG2350@1,COG2350@2 NA|NA|NA S YCII-related domain BNPNBKBE_01189 888049.HMPREF8578_0321 1.5e-52 211.8 Bacteria Bacteria COG1733@1,COG1733@2 NA|NA|NA K regulation of RNA biosynthetic process BNPNBKBE_01190 999425.HMPREF9186_01406 1.3e-154 552.4 Bacilli cylA ko:K01990,ko:K11050 ko02010,map02010 M00254,M00298 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.130 Bacteria 1V0AH@1239,4HD15@91061,COG1131@1,COG1131@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_01191 435842.HMPREF0848_01544 9.3e-134 483.0 Bacilli cylB ko:K11051 ko02010,map02010 M00298 ko00000,ko00001,ko00002,ko02000 3.A.1.130 Bacteria 1TSH0@1239,4HFNX@91061,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 type transporter BNPNBKBE_01192 435842.HMPREF0848_01545 2.6e-74 284.6 Bacilli Bacteria 1VFKH@1239,4HQ50@91061,COG3279@1,COG3279@2 NA|NA|NA K COG3279 Response regulator of the LytR AlgR family BNPNBKBE_01193 585203.SMSK564_0811 4.8e-30 137.5 Streptococcus mitis Bacteria 1U4EH@1239,2DKBP@1,2TPSA@28037,30949@2,4IE74@91061 NA|NA|NA S Protein of unknown function (DUF3021) BNPNBKBE_01194 435842.HMPREF0848_01547 5.8e-121 440.3 Bacilli mta ko:K21744 ko00000,ko03000 Bacteria 1TS6Z@1239,4HCVW@91061,COG0789@1,COG0789@2 NA|NA|NA K Transcriptional BNPNBKBE_01195 1046629.Ssal_01952 2.4e-119 434.9 Bacilli yhcA ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V50G@1239,4HIB8@91061,COG1136@1,COG1136@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_01196 1046629.Ssal_01951 3e-216 757.7 Bacilli macB_2 ko:K02004,ko:K05685 ko02010,map02010 M00258,M00709 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 Bacteria 1VU6Y@1239,4HT9M@91061,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family BNPNBKBE_01197 264199.stu0226 1.1e-272 945.3 Bacilli pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 iYO844.BSU31750 Bacteria 1TPDW@1239,4HAI4@91061,COG1488@1,COG1488@2 NA|NA|NA H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP BNPNBKBE_01198 1046629.Ssal_01948 2e-149 535.0 Bacilli nadE GO:0003674,GO:0003824,GO:0003952,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0033554,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_1910,iECW_1372.ECW_m1909,iEKO11_1354.EKO11_2035,iETEC_1333.ETEC_1772,iEcE24377_1341.EcE24377A_1961,iSFV_1184.SFV_1480,iSF_1195.SF1486,iSFxv_1172.SFxv_1676,iSSON_1240.SSON_1418,iS_1188.S1603,iWFL_1372.ECW_m1909 Bacteria 1TQ38@1239,4HA2R@91061,COG0171@1,COG0171@2 NA|NA|NA H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source BNPNBKBE_01199 1046629.Ssal_01947 2.9e-70 271.2 Firmicutes yhaI Bacteria 1VDSW@1239,COG3152@1,COG3152@2 NA|NA|NA S Protein of unknown function (DUF805) BNPNBKBE_01200 1046629.Ssal_01946 4.9e-254 883.2 Bacilli pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 1TRJN@1239,4HBZ9@91061,COG3579@1,COG3579@2 NA|NA|NA E aminopeptidase BNPNBKBE_01201 1046629.Ssal_01944 0.0 1349.3 Bacilli ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K03693,ko:K05365,ko:K05366,ko:K12555,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1TPM5@1239,4H9SA@91061,COG0744@1,COG0744@2 NA|NA|NA M penicillin-binding protein BNPNBKBE_01202 1046629.Ssal_01943 4.3e-109 400.6 Bacilli recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03700 ko00000,ko03400 Bacteria 1V3S4@1239,4HGZ7@91061,COG3331@1,COG3331@2 NA|NA|NA L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation BNPNBKBE_01203 1046629.Ssal_01942 5.8e-94 350.1 Bacilli ypsA Bacteria 1V5Q7@1239,4HECZ@91061,COG4474@1,COG4474@2 NA|NA|NA S Belongs to the UPF0398 family BNPNBKBE_01204 435842.HMPREF0848_01557 2.1e-36 158.3 Bacteria gpsB ko:K04074 ko00000,ko03036 Bacteria COG3599@1,COG3599@2 NA|NA|NA D regulation of cell shape BNPNBKBE_01205 1046629.Ssal_01940 8.1e-221 772.7 Bacilli rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016423,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 ko:K07444,ko:K12297 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1TP0X@1239,4HBKY@91061,COG0116@1,COG0116@2 NA|NA|NA L Belongs to the methyltransferase superfamily BNPNBKBE_01206 1046629.Ssal_01939 1.2e-277 962.2 Bacilli mapZ ko:K20073 ko00000 Bacteria 1VDPS@1239,2DB6P@1,32TWV@2,4HK8Y@91061 NA|NA|NA D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning BNPNBKBE_01207 1046629.Ssal_01938 0.0 1992.6 Bacilli snf 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 1TPFZ@1239,4HAIF@91061,COG0553@1,COG0553@2 NA|NA|NA L Superfamily II DNA RNA helicases, SNF2 family' BNPNBKBE_01208 40041.SZO_03140 4.8e-22 111.7 Streptococcus dysgalactiae group Bacteria 1M9KI@119603,1TXB8@1239,2DJ6Z@1,304WH@2,4I68V@91061 NA|NA|NA BNPNBKBE_01209 1046629.Ssal_01936 2e-255 887.9 Bacilli mpl GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464 6.3.2.4,6.3.2.45,6.3.2.8 ko:K01921,ko:K01924,ko:K02558 ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502 R01150,R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iSDY_1059.SDY_4251 Bacteria 1TQ5H@1239,4HAR4@91061,COG0773@1,COG0773@2 NA|NA|NA M Belongs to the MurCDEF family BNPNBKBE_01210 1046629.Ssal_01935 1e-84 319.3 Bacilli XK27_09675 ko:K07105 ko00000 Bacteria 1VB76@1239,4HM71@91061,COG0454@1,COG0454@2 NA|NA|NA K histone acetyltransferase HPA2 and related acetyltransferases BNPNBKBE_01211 1046629.Ssal_01934 3.1e-289 1000.7 Bacilli mltG ko:K07082 ko00000 Bacteria 1TS48@1239,4HAUV@91061,COG1559@1,COG1559@2 NA|NA|NA ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation BNPNBKBE_01212 1046629.Ssal_01933 1.2e-77 295.8 Bacilli greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K03624 ko00000,ko03021 Bacteria 1V44S@1239,4HGZU@91061,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides BNPNBKBE_01213 1046629.Ssal_01931 1.4e-162 578.9 Bacilli yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 1TSDN@1239,4HCC8@91061,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BNPNBKBE_01214 1046629.Ssal_01930 1.1e-43 182.2 Bacilli acyP GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036 Bacteria 1VEM9@1239,4HNN7@91061,COG1254@1,COG1254@2 NA|NA|NA C Belongs to the acylphosphatase family BNPNBKBE_01215 1046629.Ssal_01929 2.3e-128 464.9 Bacilli spoU 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 1V3JP@1239,4HCF5@91061,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family BNPNBKBE_01216 1046629.Ssal_01928 7.3e-94 349.7 Bacilli XK27_09705 6.1.1.14 ko:K01879,ko:K06950 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1V4QX@1239,4HHW0@91061,COG1418@1,COG1418@2 NA|NA|NA S HD superfamily hydrolase BNPNBKBE_01217 1046629.Ssal_01927 2.1e-99 368.6 Bacilli ybhL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06890 ko00000 Bacteria 1V779@1239,4HIX1@91061,COG0670@1,COG0670@2 NA|NA|NA S Belongs to the BI1 family BNPNBKBE_01218 1449338.JQLU01000005_gene1830 3.2e-12 79.7 Bacilli ycdA Bacteria 1V92B@1239,2CEN8@1,32ESZ@2,4HJUE@91061 NA|NA|NA S Domain of unknown function (DUF4352) BNPNBKBE_01219 1046629.Ssal_01925 6.9e-242 842.8 Bacilli lysA 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPE9@1239,4H9XW@91061,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine BNPNBKBE_01220 1046629.Ssal_01924 4.1e-90 337.4 Bacteria Bacteria COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator BNPNBKBE_01221 1046629.Ssal_01923 1.6e-36 158.3 Bacilli yneF ko:K09976 ko00000 Bacteria 1VDSU@1239,4HM8G@91061,COG3763@1,COG3763@2 NA|NA|NA S UPF0154 protein BNPNBKBE_01222 1046629.Ssal_01922 3.4e-149 534.3 Bacilli murI GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0042802,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 R00260 RC00302 ko00000,ko00001,ko01000,ko01011 iYO844.BSU28390 Bacteria 1TPPR@1239,4HA46@91061,COG0796@1,COG0796@2 NA|NA|NA M Provides the (R)-glutamate required for cell wall biosynthesis BNPNBKBE_01223 1046629.Ssal_01921 6.2e-182 643.3 Bacilli rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 1V6RN@1239,4HCP6@91061,COG0127@1,COG0127@2 NA|NA|NA F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions BNPNBKBE_01224 904306.HMPREF9192_0139 1.6e-96 358.6 Bacilli XK27_09740 ko:K07095 ko00000 Bacteria 1VA0U@1239,4HM24@91061,COG0622@1,COG0622@2 NA|NA|NA S Phosphoesterase BNPNBKBE_01225 904306.HMPREF9192_0138 2.7e-85 321.2 Bacilli ykuL Bacteria 1VFAB@1239,4HRWJ@91061,COG0517@1,COG0517@2 NA|NA|NA S CBS domain BNPNBKBE_01226 1046629.Ssal_01918 1e-126 459.5 Bacilli xerD ko:K04763 ko00000,ko03036 Bacteria 1VY7C@1239,4IT0W@91061,COG4974@1,COG4974@2 NA|NA|NA L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site BNPNBKBE_01227 904306.HMPREF9192_0136 5.3e-122 443.7 Bacilli scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K05896 ko00000,ko03036 Bacteria 1V8JV@1239,4IQZ5@91061,COG1354@1,COG1354@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves BNPNBKBE_01228 904306.HMPREF9192_0135 2.6e-95 354.8 Bacilli scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K06024 ko00000,ko03036 Bacteria 1V6HI@1239,4HIQ0@91061,COG1386@1,COG1386@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves BNPNBKBE_01229 1046629.Ssal_01915 3.4e-132 477.6 Bacilli rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.21,5.4.99.22 ko:K06178,ko:K06182,ko:K06183 ko00000,ko01000,ko03009 Bacteria 1TP68@1239,4H9MU@91061,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family BNPNBKBE_01230 1046629.Ssal_01914 1.8e-13 80.5 Bacteria yidD ko:K08998 ko00000 Bacteria COG0759@1,COG0759@2 NA|NA|NA M Could be involved in insertion of integral membrane proteins into the membrane BNPNBKBE_01231 1046629.Ssal_01912 1e-257 895.6 Bacilli trkH GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662 ko:K03498,ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4 iECDH1ME8569_1439.ECDH1ME8569_1308,iPC815.YPO3762,iSFV_1184.SFV_3651 Bacteria 1TPAF@1239,4HCWN@91061,COG0168@1,COG0168@2 NA|NA|NA P Cation transport protein BNPNBKBE_01232 1046629.Ssal_01911 1e-246 859.0 Bacilli trkA ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1TPNS@1239,4HCRM@91061,COG0569@1,COG0569@2 NA|NA|NA P Potassium transporter peripheral membrane component BNPNBKBE_01233 1046629.Ssal_01910 1.8e-95 355.1 Bacilli trmL GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 ko:K03216 ko00000,ko01000,ko03016 Bacteria 1V3GW@1239,4HFNY@91061,COG0219@1,COG0219@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily BNPNBKBE_01234 264199.stu0268 2.3e-88 331.6 Bacilli ribU GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 Bacteria 1V4BW@1239,4HHFT@91061,COG3601@1,COG3601@2 NA|NA|NA U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins BNPNBKBE_01235 264199.stu0269 5.4e-89 334.0 Bacilli bcrC 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1VF2U@1239,4HNXR@91061,COG0671@1,COG0671@2 NA|NA|NA I Membrane-associated phospholipid phosphatase BNPNBKBE_01236 264199.stu0270 7.1e-156 556.6 Bacteria ko:K20342,ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria COG1396@1,COG1396@2 NA|NA|NA K sequence-specific DNA binding BNPNBKBE_01237 1046629.Ssal_01906 0.0 1286.9 Bacilli comA ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21 Bacteria 1V77J@1239,4HAX2@91061,COG2274@1,COG2274@2 NA|NA|NA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain BNPNBKBE_01238 904306.HMPREF9192_0123 2.4e-53 214.5 Bacteria yhaI Bacteria COG3152@1,COG3152@2 NA|NA|NA L Membrane BNPNBKBE_01239 1046629.Ssal_01904 2.1e-244 851.3 Firmicutes Bacteria 1VCM1@1239,2E26M@1,32XD2@2 NA|NA|NA S Domain of unknown function (DUF4173) BNPNBKBE_01240 1046629.Ssal_01903 6.8e-95 353.2 Bacilli ureI ko:K03191 ko05120,map05120 ko00000,ko00001,ko02000 1.A.29.1.3,1.A.29.1.4,1.A.29.1.5 Bacteria 1UPV2@1239,2DC0F@1,2ZC7C@2,4IVBC@91061 NA|NA|NA S AmiS/UreI family transporter BNPNBKBE_01241 264199.stu0281 7.6e-46 189.5 Bacilli ureA GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0019627,GO:0034641,GO:0042221,GO:0043419,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071704,GO:0071941,GO:1901564,GO:1901565,GO:1901575 3.5.1.5 ko:K01430,ko:K14048 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 R00131 RC02798,RC02806 ko00000,ko00001,ko01000 iYO844.BSU36660 Bacteria 1V7GU@1239,4HIJS@91061,COG0831@1,COG0831@2 NA|NA|NA E Belongs to the urease gamma subunit family BNPNBKBE_01242 1046629.Ssal_01901 7.8e-54 216.1 Bacilli ureB GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0019627,GO:0034641,GO:0042221,GO:0043419,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071704,GO:0071941,GO:1901564,GO:1901565,GO:1901575 3.5.1.5 ko:K01429,ko:K14048 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 R00131 RC02798,RC02806 ko00000,ko00001,ko01000 Bacteria 1VAIA@1239,4HM0I@91061,COG0832@1,COG0832@2 NA|NA|NA E Belongs to the urease beta subunit family BNPNBKBE_01243 904306.HMPREF9192_0116 0.0 1156.0 Bacilli ureC 3.5.1.5 ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 R00131 RC02798,RC02806 ko00000,ko00001,ko01000 Bacteria 1TPQP@1239,4HBTS@91061,COG0804@1,COG0804@2 NA|NA|NA E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family BNPNBKBE_01244 1046629.Ssal_01898 6.6e-78 296.6 Bacteria ureE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K03187 ko00000 Bacteria COG2371@1,COG2371@2 NA|NA|NA O enzyme active site formation BNPNBKBE_01245 1046629.Ssal_01897 2.9e-128 464.5 Bacilli ureF ko:K03188 ko00000 Bacteria 1V2H0@1239,4HHW3@91061,COG0830@1,COG0830@2 NA|NA|NA O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter BNPNBKBE_01246 1046629.Ssal_01896 9.5e-112 409.5 Bacilli ureG ko:K03189,ko:K04652 ko00000,ko03110 Bacteria 1TS00@1239,4HC5C@91061,COG0378@1,COG0378@2 NA|NA|NA KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG BNPNBKBE_01247 1046629.Ssal_01895 3.7e-159 567.4 Bacilli ureD ko:K03190 ko00000 Bacteria 1TVM2@1239,4HCED@91061,COG0829@1,COG0829@2 NA|NA|NA O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter BNPNBKBE_01248 1046629.Ssal_01894 2.1e-177 628.2 Bacilli cbiM GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K02007 ko02010,map02010 M00245,M00246 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 Bacteria 1TPEN@1239,4HARY@91061,COG0310@1,COG0310@2 NA|NA|NA P PDGLE domain BNPNBKBE_01249 1046629.Ssal_01892 6.4e-137 493.4 Firmicutes ko:K02008 ko02010,map02010 M00245,M00246 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 Bacteria 1V7YC@1239,COG0619@1,COG0619@2 NA|NA|NA P cobalt transport protein BNPNBKBE_01250 1046629.Ssal_01891 1.4e-127 462.2 Bacilli cbiO GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K02006 ko02010,map02010 M00245,M00246 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 Bacteria 1V16T@1239,4HI15@91061,COG1122@1,COG1122@2 NA|NA|NA P ABC transporter BNPNBKBE_01251 1046629.Ssal_01890 6.3e-138 496.9 Bacilli ko:K02030,ko:K16957 ko02010,map02010 M00236,M00585 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.13 Bacteria 1VWFY@1239,4HW2H@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter substrate-binding protein BNPNBKBE_01252 1046629.Ssal_01889 1.6e-163 582.0 Bacilli metQ ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TQAS@1239,4HCTA@91061,COG1464@1,COG1464@2 NA|NA|NA M Belongs to the NlpA lipoprotein family BNPNBKBE_01253 1046629.Ssal_01888 2e-263 914.4 Bacilli dapE 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP2D@1239,4HB9G@91061,COG0624@1,COG0624@2 NA|NA|NA E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases BNPNBKBE_01254 1046629.Ssal_01887 6.4e-188 663.3 Bacilli metN ko:K02071 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TPPN@1239,4H9VX@91061,COG1135@1,COG1135@2 NA|NA|NA P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system BNPNBKBE_01255 1046629.Ssal_01886 1.2e-99 369.4 Bacilli metI ko:K02072 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1V0GE@1239,4HFMB@91061,COG2011@1,COG2011@2 NA|NA|NA P ABC transporter (Permease BNPNBKBE_01256 1046629.Ssal_01885 1.8e-210 738.4 Bacilli sstT GO:0003333,GO:0003674,GO:0005215,GO:0005283,GO:0005295,GO:0005310,GO:0005342,GO:0005343,GO:0005416,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006820,GO:0006835,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015077,GO:0015081,GO:0015171,GO:0015175,GO:0015291,GO:0015293,GO:0015294,GO:0015318,GO:0015370,GO:0015672,GO:0015711,GO:0015804,GO:0015849,GO:0016020,GO:0016021,GO:0017153,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032329,GO:0034220,GO:0035725,GO:0044425,GO:0044464,GO:0046873,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1903825,GO:1905039 ko:K07862 ko00000,ko02000 2.A.23.4 iAF1260.b3089,iBWG_1329.BWG_2799,iECDH10B_1368.ECDH10B_3265,iECDH1ME8569_1439.ECDH1ME8569_2984,iECH74115_1262.ECH74115_4404,iECIAI1_1343.ECIAI1_3235,iECO103_1326.ECO103_3834,iECO111_1330.ECO111_3911,iECO26_1355.ECO26_4192,iECP_1309.ECP_3180,iECSE_1348.ECSE_3370,iECSP_1301.ECSP_4063,iECUMN_1333.ECUMN_3573,iECW_1372.ECW_m3356,iECs_1301.ECs3971,iEKO11_1354.EKO11_0630,iETEC_1333.ETEC_3359,iEcDH1_1363.EcDH1_0612,iEcE24377_1341.EcE24377A_3557,iG2583_1286.G2583_3813,iJO1366.b3089,iJR904.b3089,iSFV_1184.SFV_3130,iSSON_1240.SSON_3242,iUMNK88_1353.UMNK88_3845,iWFL_1372.ECW_m3356,iY75_1357.Y75_RS16050,iYL1228.KPN_03517,iZ_1308.Z4442 Bacteria 1TPD2@1239,4HBEC@91061,COG3633@1,COG3633@2 NA|NA|NA E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) BNPNBKBE_01257 904306.HMPREF9192_0102 1.6e-157 562.0 Bacilli salL GO:0003674,GO:0003824,GO:0016740,GO:0016765 2.5.1.63,2.5.1.94 ko:K09134,ko:K21153,ko:K22205 ko00000,ko01000 Bacteria 1TSR3@1239,4HAW6@91061,COG1912@1,COG1912@2 NA|NA|NA S S-adenosyl-l-methionine hydroxide adenosyltransferase BNPNBKBE_01258 1046629.Ssal_01883 8e-94 349.7 Bacilli ko:K16924,ko:K16927 M00582 ko00000,ko00002,ko02000 3.A.1.29,3.A.1.32 Bacteria 1V1GT@1239,4HGAE@91061,COG4720@1,COG4720@2 NA|NA|NA S UPF0397 protein BNPNBKBE_01259 1046629.Ssal_01882 9.6e-308 1062.0 Bacilli ykoD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 ko:K02006,ko:K16786,ko:K16787 ko02010,map02010 M00245,M00246,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPH8@1239,4HAJM@91061,COG1122@1,COG1122@2 NA|NA|NA P abc transporter atp-binding protein BNPNBKBE_01260 1046629.Ssal_01881 1.9e-147 528.5 Bacilli cbiQ ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 iSB619.SA_RS14165 Bacteria 1TPMV@1239,4HBTW@91061,COG0619@1,COG0619@2 NA|NA|NA P cobalt transport BNPNBKBE_01261 1046629.Ssal_01880 3.7e-117 427.6 Bacilli ktrA ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1TQ9H@1239,4HBPH@91061,COG0569@1,COG0569@2 NA|NA|NA P COG0569 K transport systems, NAD-binding component BNPNBKBE_01262 1046629.Ssal_01879 1.1e-232 812.4 Bacilli ko:K03498 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1TQ4S@1239,4H9ME@91061,COG0168@1,COG0168@2 NA|NA|NA P COG0168 Trk-type K transport systems, membrane components BNPNBKBE_01263 1046629.Ssal_01878 3.2e-127 461.1 Bacilli rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 ko00000,ko01000,ko03009,ko03036 Bacteria 1TPBT@1239,4HAAZ@91061,COG0357@1,COG0357@2 NA|NA|NA J Ribosomal RNA small subunit methyltransferase G BNPNBKBE_01264 1046629.Ssal_01877 9e-90 336.3 Bacilli yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K07040 ko00000 Bacteria 1VB08@1239,4HME9@91061,COG1399@1,COG1399@2 NA|NA|NA K metal-binding, possibly nucleic acid-binding protein BNPNBKBE_01265 435842.HMPREF0848_01620 7.9e-123 446.4 Bacilli Bacteria 1TS81@1239,4H9NE@91061,COG0745@1,COG0745@2 NA|NA|NA T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain BNPNBKBE_01266 1046629.Ssal_01875 2.5e-278 964.1 Bacilli Bacteria 1UHQC@1239,4HWKS@91061,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor BNPNBKBE_01267 1046629.Ssal_01874 3e-81 307.8 Bacilli nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K07738 ko00000,ko03000 Bacteria 1V3JA@1239,4HGXA@91061,COG1327@1,COG1327@2 NA|NA|NA K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes BNPNBKBE_01268 1046629.Ssal_01873 2e-211 741.5 Bacteria dnaB ko:K03346 ko00000,ko03032 Bacteria COG3611@1,COG3611@2 NA|NA|NA L Replication initiation and membrane attachment BNPNBKBE_01269 1046629.Ssal_01872 2.4e-164 584.7 Bacilli dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K11144 ko00000,ko03032 Bacteria 1TPZX@1239,4HABS@91061,COG1484@1,COG1484@2 NA|NA|NA L Primosomal protein DnaI BNPNBKBE_01270 1046629.Ssal_01871 4.8e-246 856.7 Bacilli der GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.399,1.1.1.95 ko:K00058,ko:K03977 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 Bacteria 1TPNM@1239,4HAJ6@91061,COG1160@1,COG1160@2 NA|NA|NA S GTPase that plays an essential role in the late steps of ribosome biogenesis BNPNBKBE_01271 1046629.Ssal_01870 1.2e-104 386.0 Bacilli Bacteria 1VC9V@1239,2CH4S@1,32S58@2,4HNHW@91061 NA|NA|NA BNPNBKBE_01272 1046629.Ssal_01869 6.8e-229 799.7 Bacilli serS GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF987.Gmet_3528,iSDY_1059.SDY_2368 Bacteria 1TP4W@1239,4H9Y4@91061,COG0172@1,COG0172@2 NA|NA|NA J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) BNPNBKBE_01273 904306.HMPREF9192_0083 2.5e-62 244.6 Bacilli manO Bacteria 1VF36@1239,4HPYI@91061,COG4687@1,COG4687@2 NA|NA|NA S protein conserved in bacteria BNPNBKBE_01274 904306.HMPREF9192_0082 4e-167 594.0 Bacilli manN ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1TQA3@1239,4HA3K@91061,COG3716@1,COG3716@2 NA|NA|NA G PTS system mannose fructose sorbose family IID component BNPNBKBE_01275 904306.HMPREF9192_0081 1.2e-114 419.5 Bacilli manM ko:K02795,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1TPKK@1239,4H9QI@91061,COG3715@1,COG3715@2 NA|NA|NA G pts system BNPNBKBE_01276 1046629.Ssal_01865 4.9e-174 617.1 Bacilli manL 2.7.1.191 ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1TQJ4@1239,4H9Z8@91061,COG2893@1,COG2893@2,COG3444@1,COG3444@2 NA|NA|NA G pts system BNPNBKBE_01277 1046629.Ssal_01864 5.9e-67 260.0 Firmicutes manO Bacteria 1V6KV@1239,COG4687@1,COG4687@2 NA|NA|NA S Protein conserved in bacteria BNPNBKBE_01278 1046629.Ssal_01863 2.5e-161 574.7 Bacilli manN ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1TQA3@1239,4HA3K@91061,COG3716@1,COG3716@2 NA|NA|NA G PTS system mannose fructose sorbose family IID component BNPNBKBE_01279 1046629.Ssal_01862 4.7e-135 487.3 Bacilli manY ko:K02795,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1TPKK@1239,4H9QI@91061,COG3715@1,COG3715@2 NA|NA|NA G pts system BNPNBKBE_01280 1046629.Ssal_01861 6.2e-169 600.1 Bacilli manL 2.7.1.191 ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1TQJ4@1239,4H9Z8@91061,COG2893@1,COG2893@2,COG3444@1,COG3444@2 NA|NA|NA G pts system BNPNBKBE_01281 1046629.Ssal_01860 7.3e-135 486.5 Bacilli XK27_00940 1.2.1.70,3.5.1.9 ko:K02492,ko:K07130 ko00380,ko00630,ko00860,ko01100,ko01110,ko01120,map00380,map00630,map00860,map01100,map01110,map01120 M00038,M00121 R00988,R01959,R04109,R04911 RC00055,RC00149,RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 Bacteria 1TRBQ@1239,4HCAB@91061,COG1878@1,COG1878@2 NA|NA|NA S Metal-dependent hydrolase BNPNBKBE_01282 1046629.Ssal_01859 1.3e-153 548.9 Bacilli yitU 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TREF@1239,4H9Y9@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolases of the HAD superfamily BNPNBKBE_01283 1046629.Ssal_01858 6.2e-247 859.8 Bacilli pbuO ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 1TQC6@1239,4HANG@91061,COG2252@1,COG2252@2 NA|NA|NA S permease BNPNBKBE_01284 1046629.Ssal_01857 9.4e-77 292.7 Bacilli ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.1.221,5.1.1.1 ko:K01775,ko:K06925,ko:K07102 ko00473,ko00520,ko01100,ko01502,map00473,map00520,map01100,map01502 R00401,R08968,R11024 RC00002,RC00078,RC00285 ko00000,ko00001,ko01000,ko01011,ko03016 Bacteria 1V6CV@1239,4HIIF@91061,COG0802@1,COG0802@2 NA|NA|NA M ATPase or kinase BNPNBKBE_01285 1046629.Ssal_01856 1.1e-87 329.3 Bacteria XK27_05885 2.3.1.82 ko:K18816 br01600,ko00000,ko01000,ko01504 Bacteria COG1247@1,COG1247@2 NA|NA|NA M phosphinothricin N-acetyltransferase activity BNPNBKBE_01286 1046629.Ssal_01855 9.8e-188 662.9 Bacilli brpA Bacteria 1TR1B@1239,4HA09@91061,COG1316@1,COG1316@2 NA|NA|NA K Transcriptional BNPNBKBE_01287 1046629.Ssal_01854 2.3e-81 308.1 Bacilli rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 ko:K09748 ko00000,ko03009 Bacteria 1V6KT@1239,4HH88@91061,COG0779@1,COG0779@2 NA|NA|NA S Required for maturation of 30S ribosomal subunits BNPNBKBE_01288 1046629.Ssal_01853 2.4e-196 691.4 Bacilli nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02600,ko:K02945 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03009,ko03011,ko03021 Bacteria 1TPB3@1239,4HA7F@91061,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination BNPNBKBE_01289 904306.HMPREF9192_0067 1e-47 195.7 Bacilli ylxR ko:K02600,ko:K07742 ko00000,ko03009,ko03021 Bacteria 1VEJS@1239,4HKBY@91061,COG2740@1,COG2740@2 NA|NA|NA K Nucleic-acid-binding protein implicated in transcription termination BNPNBKBE_01290 1046629.Ssal_01850 8e-42 176.0 Firmicutes ylxQ ko:K07590,ko:K07742 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEYG@1239,COG1358@1,COG1358@2 NA|NA|NA J ribosomal protein BNPNBKBE_01291 1046629.Ssal_01848 0.0 1174.8 Bacilli infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K02519 ko00000,ko03012,ko03029 Bacteria 1TPAI@1239,4HA8S@91061,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex BNPNBKBE_01292 1046629.Ssal_01846 8.6e-57 226.1 Bacilli rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 ko:K02834 ko00000,ko03009 Bacteria 1VA0P@1239,4HII1@91061,COG0858@1,COG0858@2 NA|NA|NA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA BNPNBKBE_01293 1046629.Ssal_01845 2.2e-99 368.2 Bacilli yvdD 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 1UKED@1239,4HGSU@91061,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family BNPNBKBE_01294 264199.stu0348 3.8e-27 127.1 Bacilli femA 2.3.2.10,2.3.2.16,2.3.2.17,2.3.2.18 ko:K05363,ko:K11693,ko:K11694,ko:K11695,ko:K12554 ko00550,ko01100,map00550,map01100 R08776,R08777,R08778,R08779,R08780 RC00055,RC00064,RC00096 ko00000,ko00001,ko01000,ko01011 Bacteria 1UZIJ@1239,4HAQ3@91061,COG2348@1,COG2348@2 NA|NA|NA V protein involved in methicillin resistance BNPNBKBE_01295 435842.HMPREF0848_01649 5.5e-154 550.4 Bacilli femA 2.3.2.16,2.3.2.17,2.3.2.18 ko:K11693,ko:K11694,ko:K11695,ko:K12554 ko00550,ko01100,map00550,map01100 R08776,R08777,R08778,R08780 RC00055,RC00064,RC00096 ko00000,ko00001,ko01000,ko01011 Bacteria 1UZIJ@1239,4HAQ3@91061,COG2348@1,COG2348@2 NA|NA|NA V protein involved in methicillin resistance BNPNBKBE_01296 1046629.Ssal_01844 3.1e-270 937.2 Bacilli murE 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 Bacteria 1TPQE@1239,4H9T1@91061,COG0769@1,COG0769@2 NA|NA|NA M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan BNPNBKBE_01297 904306.HMPREF9192_0060 1.3e-288 998.4 Bacilli ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03328,ko:K06409 ko00000,ko02000 2.A.66.2,2.A.66.2.14 Bacteria 1TNYX@1239,4H9RY@91061,COG2244@1,COG2244@2 NA|NA|NA S Membrane protein involved in the export of O-antigen and teichoic acid BNPNBKBE_01298 1046629.Ssal_01842 0.0 1769.2 Bacilli pacL 3.6.3.8,3.6.3.9 ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 ko00000,ko00001,ko01000,ko04147 3.A.3.1,3.A.3.2 Bacteria 1TPF5@1239,4HTQ4@91061,COG0474@1,COG0474@2 NA|NA|NA P cation transport ATPase BNPNBKBE_01299 1046629.Ssal_01840 7.4e-200 703.0 Bacilli metB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 2.5.1.48,4.4.1.8 ko:K01739,ko:K01760 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC7@1239,4HAFQ@91061,COG0626@1,COG0626@2 NA|NA|NA E cystathionine BNPNBKBE_01300 1046629.Ssal_01839 3e-223 780.8 Bacilli malY 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 Bacteria 1TP5G@1239,4H9PE@91061,COG1168@1,COG1168@2 NA|NA|NA E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities BNPNBKBE_01301 1046629.Ssal_01838 0.0 1099.0 Bacteria 3.2.1.26,3.2.1.65 ko:K01193,ko:K01212 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R00802,R02410,R03635,R03921,R05624,R06088,R11311 RC00028,RC00077,RC03278 ko00000,ko00001,ko01000 GH32 Bacteria COG1621@1,COG1621@2 NA|NA|NA G Belongs to the glycosyl hydrolase 32 family BNPNBKBE_01302 1046629.Ssal_01837 0.0 1176.4 Bacilli sacB GO:0005575,GO:0005576 2.4.1.10,2.4.1.9,3.2.1.26 ko:K00692,ko:K01193,ko:K20811 ko00052,ko00500,ko01100,ko02020,map00052,map00500,map01100,map02020 R00801,R00802,R02410,R03635,R03921,R04194,R05140,R06088 RC00028,RC00077,RC00247 ko00000,ko00001,ko01000,ko01003 GH32,GH68 Bacteria 1TR8C@1239,4HBYU@91061,COG1621@1,COG1621@2 NA|NA|NA G Belongs to the glycosyl hydrolase 68 family BNPNBKBE_01303 1046629.Ssal_01836 5.7e-112 410.2 Bacilli upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000 iSB619.SA_RS11010 Bacteria 1TPMT@1239,4H9Y0@91061,COG0035@1,COG0035@2 NA|NA|NA F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate BNPNBKBE_01304 1046629.Ssal_01835 3.7e-105 387.5 Bacilli clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 1TQ91@1239,4HA8J@91061,COG0740@1,COG0740@2 NA|NA|NA OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins BNPNBKBE_01305 1046629.Ssal_01834 3.2e-72 277.7 Bacilli ylbF Bacteria 1V3R6@1239,4HGYS@91061,COG3679@1,COG3679@2 NA|NA|NA S Belongs to the UPF0342 family BNPNBKBE_01306 1046629.Ssal_01833 7.1e-46 189.5 Bacilli ylbG Bacteria 1VF52@1239,4HNTH@91061,COG4471@1,COG4471@2 NA|NA|NA S UPF0298 protein BNPNBKBE_01307 904306.HMPREF9192_0050 8.5e-210 736.1 Bacilli livJ ko:K01999 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 1TPQ2@1239,4H9PI@91061,COG0683@1,COG0683@2 NA|NA|NA E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component BNPNBKBE_01308 1046629.Ssal_01831 1.2e-144 519.2 Bacilli livH ko:K01997 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 1TR24@1239,4HBFZ@91061,COG0559@1,COG0559@2 NA|NA|NA E Belongs to the binding-protein-dependent transport system permease family BNPNBKBE_01309 1046629.Ssal_01830 4.9e-139 500.7 Bacilli livM ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 1TPMZ@1239,4HDIU@91061,COG4177@1,COG4177@2 NA|NA|NA E Belongs to the binding-protein-dependent transport system permease family BNPNBKBE_01310 1046629.Ssal_01829 2.4e-136 491.5 Bacilli livG ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 1TR0P@1239,4HASG@91061,COG0411@1,COG0411@2 NA|NA|NA E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component BNPNBKBE_01311 1046629.Ssal_01828 5.6e-124 450.3 Bacilli livF ko:K01996 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 1TPW4@1239,4HABJ@91061,COG0410@1,COG0410@2 NA|NA|NA E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component BNPNBKBE_01312 1046629.Ssal_01826 9.6e-110 402.9 Bacilli acuB ko:K04767 ko00000 Bacteria 1V4CD@1239,4HGX4@91061,COG0517@1,COG0517@2 NA|NA|NA S CBS domain BNPNBKBE_01313 1046629.Ssal_01825 6.3e-168 596.7 Bacilli cysK GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP30@1239,4HAMU@91061,COG0031@1,COG0031@2 NA|NA|NA E Belongs to the cysteine synthase cystathionine beta- synthase family BNPNBKBE_01314 1046629.Ssal_01824 2.9e-108 397.9 Bacilli yvyE 3.4.13.9 ko:K01271 ko00000,ko01000,ko01002 Bacteria 1V6MQ@1239,4HBIT@91061,COG1739@1,COG1739@2 NA|NA|NA S YigZ family BNPNBKBE_01315 1046629.Ssal_01823 5.7e-239 833.2 Bacilli comFA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K02240 M00429 ko00000,ko00002,ko02044 3.A.11.1 Bacteria 1TPZE@1239,4HB00@91061,COG4098@1,COG4098@2 NA|NA|NA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein) BNPNBKBE_01316 904306.HMPREF9192_0040 6.5e-98 363.6 Bacteria comFC ko:K02242 M00429 ko00000,ko00002,ko02044 Bacteria COG1040@1,COG1040@2 NA|NA|NA K competence protein BNPNBKBE_01317 1046629.Ssal_01821 1.6e-94 352.1 Bacilli hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 ko:K05808 ko00000,ko03009 Bacteria 1V1D5@1239,4HFX9@91061,COG1544@1,COG1544@2 NA|NA|NA J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase BNPNBKBE_01318 37682.EMT09379 4.1e-75 288.1 Streptophyta Viridiplantae 37HHV@33090,3GXUG@35493,COG2801@1,KOG0017@2759 NA|NA|NA T receptor-like protein kinase BNPNBKBE_01319 904306.HMPREF9192_1468 4.8e-279 966.5 Bacilli cls ko:K06131,ko:K06915 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPKY@1239,4H9TI@91061,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol BNPNBKBE_01320 904306.HMPREF9192_1469 6.3e-93 346.7 Bacilli pat 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 Bacteria 1V6X5@1239,4HIP1@91061,COG1247@1,COG1247@2 NA|NA|NA M acetyltransferase BNPNBKBE_01321 1046629.Ssal_00880 9.1e-292 1008.8 Bacilli cls ko:K06131,ko:K06915 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPKY@1239,4H9TI@91061,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol BNPNBKBE_01322 904306.HMPREF9192_1471 8.8e-124 449.5 Firmicutes alkD Bacteria 1V2U8@1239,COG4912@1,COG4912@2 NA|NA|NA L DNA alkylation repair enzyme BNPNBKBE_01323 904306.HMPREF9192_1472 2.8e-199 701.0 Bacilli asd 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC6@1239,4HA9H@91061,COG0136@1,COG0136@2 NA|NA|NA E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate BNPNBKBE_01324 1046629.Ssal_00884 1.9e-172 611.7 Bacilli dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCK@1239,4H9K9@91061,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) BNPNBKBE_01325 1046629.Ssal_00886 9.3e-124 449.5 Bacilli rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 1TPGC@1239,4HAWU@91061,COG0571@1,COG0571@2 NA|NA|NA J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism BNPNBKBE_01326 1046629.Ssal_00887 0.0 1360.9 Bacilli smc ko:K03529 ko00000,ko03036 Bacteria 1TPJV@1239,4HB89@91061,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning BNPNBKBE_01327 1046629.Ssal_00888 5.9e-89 333.6 Bacilli Bacteria 1VK6G@1239,2EQR3@1,33IAY@2,4HRX8@91061 NA|NA|NA S Protein of unknown function (DUF3278) BNPNBKBE_01328 1054460.SPPN_09895 2.4e-22 110.9 Bacilli WQ51_00220 ko:K07729 ko00000,ko03000 Bacteria 1VEKB@1239,4IPQ1@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix domain BNPNBKBE_01329 1046629.Ssal_00890 3.9e-198 697.2 Bacilli pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPFW@1239,4HAVN@91061,COG0016@1,COG0016@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily BNPNBKBE_01330 904306.HMPREF9192_1478 6.4e-93 346.7 Bacilli paiA 2.3.1.57 ko:K22441 ko00000,ko01000 Bacteria 1VDFK@1239,4HMHW@91061,COG0454@1,COG0456@2 NA|NA|NA K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases BNPNBKBE_01331 1046629.Ssal_00892 0.0 1527.7 Bacilli pheT GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890,ko:K06878 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_2160,iPC815.YPO2428 Bacteria 1TP98@1239,4HAQ9@91061,COG0072@1,COG0072@2,COG0073@1,COG0073@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily BNPNBKBE_01333 1046629.Ssal_00894 7e-56 223.0 Firmicutes nrdD_1 1.1.98.6,1.17.4.1 ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024,R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1TT3U@1239,COG0209@1,COG0209@2 NA|NA|NA F Ribonucleoside-triphosphate reductase BNPNBKBE_01334 1046629.Ssal_00896 9.7e-236 822.4 Bacilli XK27_08130 Bacteria 1TPS5@1239,4HBNK@91061,COG1167@1,COG1167@2 NA|NA|NA K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs BNPNBKBE_01336 904306.HMPREF9192_1484 1.6e-83 315.5 Firmicutes Bacteria 1V6QK@1239,COG4720@1,COG4720@2 NA|NA|NA S ECF-type riboflavin transporter, S component BNPNBKBE_01337 904306.HMPREF9192_1485 2.4e-145 521.5 Bacilli pdxK 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TRCR@1239,4HHME@91061,COG2240@1,COG2240@2 NA|NA|NA H Belongs to the pyridoxine kinase family BNPNBKBE_01338 1046629.Ssal_00900 2e-78 298.5 Bacilli XK27_01265 ko:K16923 M00582 ko00000,ko00002,ko02000 3.A.1.28 Bacteria 1VC0F@1239,4HMJM@91061,COG4720@1,COG4720@2 NA|NA|NA S ECF-type riboflavin transporter, S component BNPNBKBE_01339 1046629.Ssal_00901 3.3e-294 1016.9 Bacilli yfmM ko:K06158 ko00000,ko03012 Bacteria 1TPAX@1239,4HC58@91061,COG0488@1,COG0488@2 NA|NA|NA S abc transporter atp-binding protein BNPNBKBE_01340 1046629.Ssal_00902 3.9e-254 883.6 Bacilli noxE Bacteria 1TPWW@1239,4H9U7@91061,COG0446@1,COG0446@2 NA|NA|NA P NADH oxidase BNPNBKBE_01341 1046629.Ssal_00903 5.9e-180 636.7 Bacilli ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPSY@1239,4HB0Z@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily. LDH family BNPNBKBE_01342 1046629.Ssal_00904 0.0 1436.4 Bacilli gyrA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TP2Z@1239,4HAHY@91061,COG0188@1,COG0188@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner BNPNBKBE_01343 1046629.Ssal_00905 7.9e-132 476.5 Bacilli srtA 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 1V83Z@1239,4HIA0@91061,COG3764@1,COG3764@2 NA|NA|NA M Sortase (surface protein transpeptidase) BNPNBKBE_01344 862971.SANR_1774 1.6e-39 168.3 Streptococcus anginosus group Bacteria 1TRSF@1239,42EI8@671232,4HCMP@91061,COG2826@1,COG2826@2 NA|NA|NA L Integrase core domain BNPNBKBE_01345 435842.HMPREF0848_00996 0.0 1556.2 Firmicutes Bacteria 1V0PX@1239,COG5263@1,COG5263@2 NA|NA|NA M Putative cell wall binding repeat BNPNBKBE_01346 1046629.Ssal_00725 1.1e-222 780.0 Bacteria Bacteria COG5263@1,COG5263@2 NA|NA|NA S dextransucrase activity BNPNBKBE_01348 585202.SMSK321_1115 0.0 1446.8 Streptococcus mitis mprF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 ko:K07027,ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 2.A.1.3.37,4.D.2 iYO844.BG12900 Bacteria 1TQI2@1239,2TQ66@28037,4HBHU@91061,COG0392@1,COG0392@2,COG2898@1,COG2898@2 NA|NA|NA S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms BNPNBKBE_01349 888048.HMPREF8577_1207 3.1e-162 577.8 Bacilli mleP ko:K07088 ko00000 Bacteria 1UY4N@1239,4HDX5@91061,COG0679@1,COG0679@2 NA|NA|NA S auxin efflux carrier BNPNBKBE_01350 888048.HMPREF8577_1208 2.5e-308 1063.9 Bacilli sfcA 1.1.1.38,4.1.1.101 ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 R00214,R11074 RC00105,RC00282 ko00000,ko00001,ko01000 Bacteria 1TPJ3@1239,4HBF1@91061,COG0281@1,COG0281@2 NA|NA|NA C malic enzyme BNPNBKBE_01351 888833.HMPREF9421_0710 2.7e-47 194.5 Bacilli Bacteria 1VK84@1239,4HN0W@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix BNPNBKBE_01352 388919.SSA_0295 1.5e-118 432.6 Streptococcus sanguinis mleR Bacteria 1V5VW@1239,1WQQZ@1305,4HHDY@91061,COG0583@1,COG0583@2 NA|NA|NA K malolactic fermentation system BNPNBKBE_01353 1046629.Ssal_00722 7.8e-132 476.5 Bacilli XK27_00785 Bacteria 1V3A5@1239,28MHE@1,2ZAUA@2,4HZB2@91061 NA|NA|NA S CAAX protease self-immunity BNPNBKBE_01354 1046629.Ssal_00721 3e-238 830.9 Bacteria ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily BNPNBKBE_01355 1046629.Ssal_00720 6.2e-67 260.0 Firmicutes rmaI Bacteria 1VEYN@1239,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator, MarR family BNPNBKBE_01356 435842.HMPREF0848_01001 1.1e-91 342.8 Bacilli maa 2.3.1.79 ko:K00661 ko00000,ko01000 Bacteria 1TQEX@1239,4HAJ0@91061,COG0110@1,COG0110@2 NA|NA|NA GK Maltose O-acetyltransferase BNPNBKBE_01357 1046629.Ssal_00718 1.2e-137 495.7 Bacteria Bacteria COG2220@1,COG2220@2 NA|NA|NA S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity BNPNBKBE_01358 1046629.Ssal_00717 0.0 2548.5 Bacteria 3.5.1.28 ko:K01448,ko:K13733,ko:K20276 ko01503,ko02024,ko05100,map01503,map02024,map05100 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria COG3266@1,COG3266@2,COG4932@1,COG4932@2 NA|NA|NA M domain protein BNPNBKBE_01359 1046629.Ssal_00714 0.0 2460.6 Bacilli GO:0005575,GO:0005576 2.4.1.5 ko:K00689,ko:K20276 ko00500,ko02020,ko02024,map00500,map02020,map02024 R02120,R06066 RC00028 ko00000,ko00001,ko01000 GH13 Bacteria 1VQXK@1239,4HEIA@91061,COG0366@1,COG0366@2,COG5263@1,COG5263@2 NA|NA|NA M KxYKxGKxW signal domain protein BNPNBKBE_01360 997830.HMPREF1124_0293 5.4e-24 117.5 Streptococcus infantis Bacteria 1TWFX@1239,2DKIY@1,309MV@2,43G50@68892,4I598@91061 NA|NA|NA BNPNBKBE_01362 1046629.Ssal_01188 1.9e-89 335.1 Bacilli yybC Bacteria 1V8UN@1239,2BWFV@1,32QWV@2,4HK47@91061 NA|NA|NA BNPNBKBE_01363 1046629.Ssal_01189 1.1e-75 289.3 Bacilli XK27_03610 Bacteria 1V77V@1239,4HKYX@91061,COG0454@1,COG0456@2 NA|NA|NA K Gnat family BNPNBKBE_01364 1046629.Ssal_01190 1.5e-56 225.3 Bacilli rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6DB@1239,4HH2W@91061,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit BNPNBKBE_01365 1046629.Ssal_01191 8.1e-28 129.0 Bacilli rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02916 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VF5W@1239,4HNIQ@91061,COG0291@1,COG0291@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL35 family BNPNBKBE_01366 1046629.Ssal_01192 1e-85 322.8 Bacilli infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 1V1RC@1239,4HI4P@91061,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins BNPNBKBE_01367 1046629.Ssal_01193 3.1e-119 434.5 Bacilli cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.17.7.4,2.5.1.19,2.7.1.26,2.7.4.25,2.7.7.2,6.3.2.1 ko:K00800,ko:K00945,ko:K02945,ko:K03527,ko:K03977,ko:K11753,ko:K13799 ko00240,ko00400,ko00410,ko00740,ko00770,ko00900,ko01100,ko01110,ko01130,ko01230,ko03010,map00240,map00400,map00410,map00740,map00770,map00900,map01100,map01110,map01130,map01230,map03010 M00022,M00052,M00096,M00119,M00125,M00178 R00158,R00161,R00512,R00549,R01665,R02473,R03460,R05884,R08210 RC00002,RC00017,RC00096,RC00141,RC00350,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03009,ko03011 iPC815.YPO1391,iSDY_1059.SDY_2348 Bacteria 1V3IA@1239,4HFZE@91061,COG0283@1,COG0283@2 NA|NA|NA F Belongs to the cytidylate kinase family. Type 1 subfamily BNPNBKBE_01368 904306.HMPREF9192_1655 9.4e-17 94.0 Bacilli Bacteria 1VD79@1239,4HT02@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain BNPNBKBE_01369 904306.HMPREF9192_1653 1.2e-85 322.4 Bacilli ebsA Bacteria 1VQ5S@1239,2FI04@1,349T2@2,4HYC5@91061 NA|NA|NA S Family of unknown function (DUF5322) BNPNBKBE_01370 1046629.Ssal_01196 2.2e-229 801.2 Bacilli pepT GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0034701,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045148,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.4 ko:K01258 ko00000,ko01000,ko01002 Bacteria 1TP3A@1239,4HAZE@91061,COG2195@1,COG2195@2 NA|NA|NA E Cleaves the N-terminal amino acid of tripeptides BNPNBKBE_01371 1046629.Ssal_01197 0.0 1302.3 Bacilli lytC 3.4.17.14,3.5.1.28 ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 M00651,M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 Bacteria 1TR6H@1239,4H9U6@91061,COG0860@1,COG0860@2,COG1705@1,COG1705@2 NA|NA|NA M N-acetylmuramoyl-L-alanine amidase BNPNBKBE_01372 1046629.Ssal_01199 3.3e-95 354.4 Bacilli lepB 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1V2BJ@1239,4HGCB@91061,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family BNPNBKBE_01373 1046629.Ssal_01200 1.9e-220 771.5 Bacilli Bacteria 1TT97@1239,4HAIA@91061,COG0457@1,COG0457@2 NA|NA|NA G COG0457 FOG TPR repeat BNPNBKBE_01374 1046629.Ssal_01201 4e-175 620.9 Bacilli yubA Bacteria 1TQ84@1239,4H9SR@91061,COG0628@1,COG0628@2 NA|NA|NA S permease BNPNBKBE_01375 1046629.Ssal_01202 4.3e-91 340.5 Bacilli mutX 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1V66I@1239,4HHRE@91061,COG1051@1,COG1051@2 NA|NA|NA F NTP pyrophosphohydrolases including oxidative damage repair enzymes BNPNBKBE_01376 904306.HMPREF9192_1646 7.3e-164 583.2 Bacilli ftsX GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0031224,GO:0031226,GO:0032506,GO:0034097,GO:0040007,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531 ko:K09811,ko:K09812 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 1TPND@1239,4HA5A@91061,COG2177@1,COG2177@2 NA|NA|NA D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation BNPNBKBE_01377 264199.stu1145 3.2e-124 451.1 Bacilli ftsE GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 ko:K09811,ko:K09812 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 1TP58@1239,4H9Z2@91061,COG2884@1,COG2884@2 NA|NA|NA D cell division ATP-binding protein FtsE BNPNBKBE_01378 1046629.Ssal_01205 5.7e-183 646.7 Bacilli prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 1TPSB@1239,4H9N2@91061,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA BNPNBKBE_01379 1046629.Ssal_01206 1e-204 719.2 Bacilli queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 ko00000,ko01000,ko03016 Bacteria 1TP6Q@1239,4HAEW@91061,COG1600@1,COG1600@2 NA|NA|NA C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) BNPNBKBE_01380 1046629.Ssal_01207 2.1e-154 551.6 Bacilli yjjH Bacteria 1V9B5@1239,4HJX0@91061,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase BNPNBKBE_01381 1046629.Ssal_01208 8.5e-131 473.0 Bacilli nfrA 1.5.1.38,1.5.1.39 ko:K19285,ko:K19286 ko00740,ko01100,map00740,map01100 R05705,R05706 RC00126 ko00000,ko00001,ko01000 Bacteria 1UB8S@1239,4HEGP@91061,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase BNPNBKBE_01382 1046629.Ssal_01209 0.0 1608.6 Bacilli pacL 3.6.3.8 ko:K01537 ko00000,ko01000 3.A.3.2 Bacteria 1TPF5@1239,4H9S5@91061,COG0474@1,COG0474@2 NA|NA|NA P cation transport ATPase BNPNBKBE_01383 1046629.Ssal_01211 5.3e-68 263.5 Bacteria ywiB Bacteria COG4506@1,COG4506@2 NA|NA|NA S Domain of unknown function (DUF1934) BNPNBKBE_01384 1046629.Ssal_01213 9.1e-145 519.6 Bacilli XK27_00115 2.3.1.128 ko:K03789 ko00000,ko01000,ko03009 Bacteria 1VD7Z@1239,4HGYD@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase GNAT family BNPNBKBE_01385 904306.HMPREF9192_1636 2.7e-146 524.6 Bacilli yidA GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050308 Bacteria 1TR16@1239,4HCZ6@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolases of the HAD superfamily BNPNBKBE_01386 904306.HMPREF9192_1635 6.7e-226 789.6 Bacilli murM 2.3.2.10,2.3.2.16 ko:K05363,ko:K11693 ko00550,ko01100,map00550,map01100 R08776,R08779 RC00055,RC00096 ko00000,ko00001,ko01000,ko01011 Bacteria 1TRZU@1239,4HC1Z@91061,COG2348@1,COG2348@2 NA|NA|NA V protein involved in methicillin resistance BNPNBKBE_01387 435842.HMPREF0848_00563 1.9e-56 224.9 Bacilli ko:K09790 ko00000 Bacteria 1VC3R@1239,4HMWE@91061,COG2832@1,COG2832@2 NA|NA|NA S Protein of unknown function (DUF454) BNPNBKBE_01388 1046629.Ssal_01219 5.1e-153 547.0 Bacilli vicX 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 1TQ8E@1239,4HAKD@91061,COG1235@1,COG1235@2 NA|NA|NA S Metal-dependent hydrolases of the beta-lactamase superfamily I BNPNBKBE_01389 1046629.Ssal_01220 2.2e-230 804.7 Bacilli vicK 2.7.13.3 ko:K07652 ko02020,map02020 M00459 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQ1H@1239,4HA52@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase BNPNBKBE_01390 904306.HMPREF9192_1631 6.4e-128 463.4 Bacilli Bacteria 1TPQG@1239,4HA8Q@91061,COG0745@1,COG0745@2 NA|NA|NA KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain BNPNBKBE_01391 904306.HMPREF9192_1626 1.6e-140 505.4 Bacilli glnQ 3.6.3.21 ko:K02028,ko:K10041 ko02010,map02010 M00228,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E abc transporter atp-binding protein BNPNBKBE_01392 1046629.Ssal_01223 1.8e-145 521.9 Bacilli peb1A GO:0005575,GO:0005623,GO:0009986,GO:0044464 ko:K10039 ko02010,map02010 M00228 ko00000,ko00001,ko00002,ko02000 3.A.1.3 Bacteria 1TT11@1239,4HAHV@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC-type amino acid transport signal transduction systems, periplasmic component domain BNPNBKBE_01393 904306.HMPREF9192_1624 1.9e-116 425.2 Bacilli gltJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02029,ko:K10003,ko:K10040 ko02010,ko02020,map02010,map02020 M00228,M00230,M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.19,3.A.1.3.4 iJN746.PP_1070 Bacteria 1TQ5K@1239,4HE9C@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter (Permease BNPNBKBE_01394 435842.HMPREF0848_01018 5.4e-189 666.8 Bacilli nss Bacteria 1V6NM@1239,4HISP@91061,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups BNPNBKBE_01395 585203.SMSK564_1819 3.6e-16 90.5 Streptococcus mitis Bacteria 1U4K0@1239,2DKDD@1,2TQ0I@28037,3097M@2,4IEBR@91061 NA|NA|NA S Accessory secretory protein Sec, Asp5 BNPNBKBE_01396 1008453.HMPREF9957_1677 2.6e-17 94.0 Streptococcus mitis Bacteria 1U4KE@1239,2AHFC@1,2TQ11@28037,317SM@2,4IEC5@91061 NA|NA|NA S Accessory secretory protein Sec Asp4 BNPNBKBE_01397 904306.HMPREF9192_1018 1.1e-245 855.5 Bacilli gtf2 Bacteria 1TQZR@1239,4HEYJ@91061,COG0438@1,COG0438@2 NA|NA|NA M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1 BNPNBKBE_01398 904306.HMPREF9192_1017 3.7e-282 976.9 Bacilli gtf1 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1TR6K@1239,4HGDG@91061,COG0438@1,COG0438@2 NA|NA|NA M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon BNPNBKBE_01399 435842.HMPREF0848_01023 0.0 1517.7 Bacilli secA2 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1TRJA@1239,4HCH0@91061,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane BNPNBKBE_01400 904306.HMPREF9192_1015 5e-78 297.0 Bacilli asp3 ko:K12270 ko00000,ko02044 3.A.5.10 Bacteria 1V6D1@1239,2AFSZ@1,315V3@2,4HS4W@91061 NA|NA|NA S Accessory Sec system protein Asp3 BNPNBKBE_01401 904306.HMPREF9192_1014 1.3e-290 1005.0 Bacilli asp2 3.4.11.5 ko:K01259,ko:K06889,ko:K12269 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002,ko02044 3.A.5.10 Bacteria 1TSWW@1239,4HB1I@91061,COG1073@1,COG1073@2 NA|NA|NA S Accessory Sec system protein Asp2 BNPNBKBE_01402 904306.HMPREF9192_1013 1.5e-291 1008.1 Bacilli asp1 ko:K12268 ko00000,ko02044 3.A.5.10 Bacteria 1V1BC@1239,2CI7G@1,2ZBRM@2,4HKRQ@91061 NA|NA|NA S Accessory Sec system protein Asp1 BNPNBKBE_01403 435842.HMPREF0848_01027 1.2e-211 742.3 Bacilli secY2 ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5 Bacteria 1V59T@1239,4HH1U@91061,COG0201@1,COG0201@2 NA|NA|NA U Part of the accessory SecA2 SecY2 system specifically required for export of BNPNBKBE_01404 264199.stu1392 0.0 1369.8 Bacilli Bacteria 1VATJ@1239,4HG1M@91061,COG1216@1,COG1216@2,COG1442@1,COG1442@2 NA|NA|NA M family 8 BNPNBKBE_01405 1419814.V470_02690 0.0 1437.6 Bacilli sbcC ko:K03546 ko00000,ko03400 Bacteria 1TPCS@1239,4H9Q3@91061,COG0419@1,COG0419@2 NA|NA|NA L ATPase involved in DNA repair BNPNBKBE_01406 904306.HMPREF9192_1009 1.1e-217 762.3 Bacilli sbcD ko:K03547 ko00000,ko03400 Bacteria 1TQY6@1239,4HAKB@91061,COG0420@1,COG0420@2 NA|NA|NA L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity BNPNBKBE_01407 1046629.Ssal_00675 0.0 1453.3 Bacteria Bacteria COG3266@1,COG3266@2 NA|NA|NA GM domain, Protein BNPNBKBE_01408 1046629.Ssal_00673 0.0 3090.8 Bacilli zmpB GO:0005575,GO:0005618,GO:0005623,GO:0009986,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K08643 ko00000,ko01000,ko01002 Bacteria 1TRAR@1239,4HEH7@91061,COG3064@1,COG3064@2,COG3583@1,COG3583@2 NA|NA|NA M signal peptide protein, YSIRK family BNPNBKBE_01409 257314.LJ_1419 2.5e-44 184.9 Lactobacillaceae Bacteria 1U7WG@1239,29QD3@1,30BCB@2,3FA9C@33958,4IHTV@91061 NA|NA|NA S Bacteriophage holin of superfamily 6 (Holin_LLH) BNPNBKBE_01410 891391.LAC30SC_06460 2.3e-11 74.3 Lactobacillaceae Bacteria 1U8FX@1239,29QQA@1,30BQ1@2,3FAXX@33958,4IIDS@91061 NA|NA|NA BNPNBKBE_01411 97137.C821_00023 1.4e-07 62.8 Lactobacillaceae Bacteria 1U70Q@1239,2DKTK@1,30ARH@2,3F8TM@33958,4IGV1@91061 NA|NA|NA BNPNBKBE_01414 257314.LJ_1423 3e-49 203.0 Lactobacillaceae Bacteria 1V5YB@1239,3FBEX@33958,4IPZC@91061,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase BNPNBKBE_01416 762051.LKI_09735 1.2e-37 164.5 Bacilli Bacteria 1VA6F@1239,4HM18@91061,COG4926@1,COG4926@2 NA|NA|NA S Prophage endopeptidase tail BNPNBKBE_01417 438780.D2KRB8_9CAUD 1.3e-60 240.0 Siphoviridae GO:0005575,GO:0019012,GO:0044423,GO:0098015 Viruses 4QBF8@10239,4QKN2@10699,4QPI9@28883,4QUS7@35237 NA|NA|NA S Phage tail protein BNPNBKBE_01418 1423758.BN55_04310 1.1e-131 478.8 Lactobacillaceae ko:K11060,ko:K21471 ko00000,ko01000,ko01002,ko01011,ko02042 Bacteria 1UZN8@1239,3F3T2@33958,4HGQG@91061,COG0791@1,COG0791@2,COG3953@1,COG3953@2,COG5283@1,COG5283@2,COG5412@1,COG5412@2 NA|NA|NA M Phage tail tape measure protein TP901 BNPNBKBE_01419 1423767.BALU01000006_gene766 8.6e-36 157.1 Lactobacillaceae Bacteria 1VCXU@1239,2E0P6@1,32W81@2,3F98U@33958,4HM42@91061 NA|NA|NA S Bacteriophage Gp15 protein BNPNBKBE_01420 1140001.I571_02117 6.9e-08 63.9 Enterococcaceae Bacteria 1TZA4@1239,2BJJ5@1,32DW7@2,4B2N3@81852,4I8HT@91061 NA|NA|NA BNPNBKBE_01421 1423767.BALU01000006_gene768 4.9e-44 184.5 Lactobacillaceae Bacteria 1VAG5@1239,3F8R0@33958,4HMMA@91061,COG5492@1,COG5492@2 NA|NA|NA N domain, Protein BNPNBKBE_01422 1423790.BN53_04205 5.8e-17 94.0 Lactobacillaceae Bacteria 1U7XE@1239,2BND6@1,32H0V@2,3FAAH@33958,4IHUT@91061 NA|NA|NA S Minor capsid protein from bacteriophage BNPNBKBE_01423 1423790.BN53_04210 1.2e-21 109.4 Lactobacillaceae Bacteria 1U84F@1239,2AHWR@1,3189M@2,3FAIJ@33958,4II1W@91061 NA|NA|NA S Minor capsid protein BNPNBKBE_01424 1423767.BALU01000006_gene771 1.6e-23 115.5 Lactobacillaceae Bacteria 1U7RX@1239,2BKZJ@1,32FGA@2,3FA3B@33958,4IHP9@91061 NA|NA|NA S Minor capsid protein BNPNBKBE_01425 1423767.BALU01000006_gene772 1.2e-30 139.4 Lactobacillaceae Bacteria 1U7TX@1239,2BMG9@1,32G0Z@2,3FA66@33958,4IHRC@91061 NA|NA|NA BNPNBKBE_01426 1423767.BALU01000006_gene773 1.5e-144 519.2 Lactobacillaceae gpG Bacteria 1U6NR@1239,2BZ9Z@1,2Z97E@2,3F6D9@33958,4HF9M@91061 NA|NA|NA BNPNBKBE_01427 1423767.BALU01000006_gene774 2e-48 199.1 Lactobacillaceae Bacteria 1VFIK@1239,2DPCU@1,331IS@2,3F6BA@33958,4HPAM@91061 NA|NA|NA S Phage minor structural protein GP20 BNPNBKBE_01429 745718.JADT01000019_gene1515 2.5e-09 69.3 Flavobacteriia Bacteria 1I1Y1@117743,2DKW0@1,30IG3@2,4NPI4@976 NA|NA|NA L Intron encoded nuclease repeat motif BNPNBKBE_01430 1423767.BALU01000006_gene776 9.6e-86 323.6 Lactobacillaceae Bacteria 1UHNF@1239,2DC26@1,2ZCK6@2,3F6ME@33958,4IS4D@91061 NA|NA|NA S Phage minor capsid protein 2 BNPNBKBE_01431 1423790.BN53_04240 1.7e-184 652.5 Lactobacillaceae Bacteria 1UYMH@1239,2BX0Z@1,2Z88Q@2,3F75T@33958,4HC7J@91061 NA|NA|NA S Phage portal protein, SPP1 Gp6-like BNPNBKBE_01432 1423767.BALU01000006_gene778 3.3e-215 754.2 Lactobacillaceae ko:K06909 ko00000 Bacteria 1TRQP@1239,3F562@33958,4HCUQ@91061,COG1783@1,COG1783@2 NA|NA|NA S Terminase RNAseH like domain BNPNBKBE_01433 1423767.BALU01000006_gene779 2.5e-89 335.1 Lactobacillaceae Bacteria 1V6XW@1239,3F7DT@33958,4HIUS@91061,COG2963@1,COG2963@2 NA|NA|NA L transposase activity BNPNBKBE_01435 1423767.BALU01000006_gene783 4.4e-105 387.5 Lactobacillaceae Bacteria 1TPHP@1239,3F700@33958,4HC9M@91061,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the N(4) N(6)-methyltransferase family BNPNBKBE_01436 557436.Lreu_0830 7.4e-39 166.8 Bacilli Bacteria 1W1P1@1239,292Y9@1,2ZQFR@2,4I14X@91061 NA|NA|NA BNPNBKBE_01437 557436.Lreu_0829 3.3e-102 377.9 Lactobacillaceae 1.8.4.10,1.8.4.8,2.7.7.4 ko:K00390,ko:K00957 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R02021,R04929 RC00007,RC02809,RC02862,RC02889 ko00000,ko00001,ko00002,ko01000 Bacteria 1U62J@1239,3F6VP@33958,4IFRP@91061,COG0175@1,COG0175@2 NA|NA|NA EH sulfate reduction BNPNBKBE_01438 557436.Lreu_1281 1e-36 159.8 Lactobacillaceae Bacteria 1VMB8@1239,2EG6W@1,339YS@2,3F80J@33958,4HRH5@91061 NA|NA|NA BNPNBKBE_01443 324831.LGAS_0591 2.5e-72 278.1 Lactobacillaceae rusA 3.1.22.4 ko:K01160 ko00000,ko01000,ko03400 Bacteria 1TU9T@1239,3F7T5@33958,4IG7K@91061,COG4570@1,COG4570@2 NA|NA|NA L Endodeoxyribonuclease RusA BNPNBKBE_01445 1046629.Ssal_01793 1.1e-21 108.6 Bacilli fruR ko:K03436 ko00000,ko03000 Bacteria 1TSF8@1239,4HDT9@91061,COG1349@1,COG1349@2 NA|NA|NA K transcriptional BNPNBKBE_01446 322159.STER_0445 2.2e-35 154.5 Bacilli pfkB 2.7.1.11,2.7.1.56 ko:K00882,ko:K16370 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00345 R00756,R02071,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ36@1239,4HANU@91061,COG1105@1,COG1105@2 NA|NA|NA H Belongs to the carbohydrate kinase PfkB family. LacC subfamily BNPNBKBE_01447 435842.HMPREF0848_01223 5.3e-163 580.5 Bacilli Bacteria 1UQA9@1239,4HBNE@91061,COG2199@1,COG2199@2 NA|NA|NA T Diguanylate cyclase BNPNBKBE_01448 435842.HMPREF0848_01224 1.4e-147 529.3 Bacilli 2.4.1.83 ko:K00721,ko:K20534 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003,ko01005,ko02000 4.D.2.1.9 GT2 Bacteria 1TQ8C@1239,4HDD4@91061,COG0463@1,COG0463@2,COG2246@1,COG2246@2 NA|NA|NA M COG0463, glycosyltransferases involved in cell wall biogenesis BNPNBKBE_01449 435842.HMPREF0848_01225 0.0 1481.1 Bacilli bcsA 2.4.1.12 ko:K00694 ko00500,ko01100,ko02026,map00500,map01100,map02026 R02889 RC00005 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.3.1.2,4.D.3.1.5,4.D.3.1.6 GT2 Bacteria 1TSD3@1239,4HD23@91061,COG1215@1,COG1215@2 NA|NA|NA M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis BNPNBKBE_01450 435842.HMPREF0848_01226 0.0 1113.6 Bacilli Bacteria 1TPQ9@1239,28KEZ@1,2ZA17@2,4HFER@91061 NA|NA|NA BNPNBKBE_01451 873447.SPB_1682 5.1e-27 126.3 Bacilli uvrX 2.7.7.7 ko:K02346,ko:K03502,ko:K14161 ko00000,ko01000,ko03400 Bacteria 1TP42@1239,4HA1P@91061,COG0389@1,COG0389@2 NA|NA|NA L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII BNPNBKBE_01452 435842.HMPREF0848_01227 1.2e-74 285.8 Bacilli Bacteria 1VUJF@1239,2F0Z4@1,33U0S@2,4I1M0@91061 NA|NA|NA BNPNBKBE_01453 435842.HMPREF0848_01228 7.6e-110 403.3 Bacilli Bacteria 1TQWX@1239,4HY19@91061,COG2932@1,COG2932@2 NA|NA|NA K Peptidase S24-like protein BNPNBKBE_01454 435842.HMPREF0848_01229 8.9e-107 393.3 Bacilli Bacteria 1VPKW@1239,4HZKQ@91061,COG2856@1,COG2856@2 NA|NA|NA E IrrE N-terminal-like domain BNPNBKBE_01455 888746.HMPREF9180_1568 9.9e-93 346.7 Bacilli Bacteria 1VV0W@1239,2EDPB@1,337J0@2,4HVVE@91061 NA|NA|NA BNPNBKBE_01456 562983.HMPREF0433_00672 6.4e-77 294.3 Bacilli Bacteria 1VWCK@1239,2F5IH@1,33Y3W@2,4HW3I@91061 NA|NA|NA BNPNBKBE_01457 563038.HMPREF0851_01447 1.9e-44 185.7 Bacilli Bacteria 1W3A8@1239,2DEIC@1,2ZN3X@2,4HZMP@91061 NA|NA|NA BNPNBKBE_01458 264199.stu1598 6.6e-42 176.4 Bacilli yaaK ko:K09747 ko00000 Bacteria 1VA1S@1239,4HKH3@91061,COG0718@1,COG0718@2 NA|NA|NA S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection BNPNBKBE_01460 1046629.Ssal_00444 1.9e-124 451.8 Bacilli ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQC9@1239,4HB8D@91061,COG1136@1,COG1136@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_01461 1046629.Ssal_00443 0.0 1555.0 Bacilli ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPHU@1239,4HA2C@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter (Permease BNPNBKBE_01462 435842.HMPREF0848_01235 2.7e-49 201.1 Bacilli Bacteria 1UZ0H@1239,4HGGU@91061,COG0789@1,COG0789@2 NA|NA|NA K transcriptional regulator, MerR family BNPNBKBE_01463 904306.HMPREF9192_0778 8.3e-105 386.3 Bacilli dnaQ 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1V8EQ@1239,4HJYT@91061,COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III BNPNBKBE_01464 1046629.Ssal_00439 9.1e-42 176.8 Bacilli WQ51_02910 Bacteria 1VNC1@1239,2EHT6@1,33BIW@2,4HRJ5@91061 NA|NA|NA S Protein of unknown function, DUF536 BNPNBKBE_01465 1046629.Ssal_00437 6.8e-65 253.1 Bacilli XK27_02560 ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1VX9Z@1239,4HXCM@91061,COG2151@1,COG2151@2 NA|NA|NA S cog cog2151 BNPNBKBE_01466 904306.HMPREF9192_0774 0.0 1132.5 Bacilli ilvD GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1R@1239,4H9ZG@91061,COG0129@1,COG0129@2 NA|NA|NA E Belongs to the IlvD Edd family BNPNBKBE_01467 1046629.Ssal_00435 6.3e-221 773.1 Bacilli ytfP ko:K07007 ko00000 Bacteria 1TQ6E@1239,4HAAT@91061,COG2081@1,COG2081@2 NA|NA|NA S Flavoprotein BNPNBKBE_01469 1046629.Ssal_00434 3.1e-121 441.0 Bacilli trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33 ko:K02493,ko:K03439 R10806 RC00003,RC03279 ko00000,ko01000,ko03012,ko03016 Bacteria 1TQCA@1239,4HC08@91061,COG0220@1,COG0220@2 NA|NA|NA J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA BNPNBKBE_01470 1046629.Ssal_00433 7.1e-152 543.1 Bacilli ytmP 2.7.1.89 ko:K07251 ko00730,ko01100,map00730,map01100 R02134 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1UMFY@1239,4HBF9@91061,COG0510@1,COG0510@2 NA|NA|NA M Phosphotransferase BNPNBKBE_01471 1046629.Ssal_00432 1.3e-174 619.0 Firmicutes ecsB ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V9K7@1239,COG4473@1,COG4473@2 NA|NA|NA U Bacterial ABC transporter protein EcsB BNPNBKBE_01472 1046629.Ssal_00431 8.4e-131 473.0 Bacilli ecsA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQIH@1239,4HA2B@91061,COG1131@1,COG1131@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_01473 904306.HMPREF9192_0767 1.1e-71 275.8 Bacilli hit ko:K02503 ko00000,ko04147 Bacteria 1V9ZJ@1239,4HIG2@91061,COG0537@1,COG0537@2 NA|NA|NA FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases BNPNBKBE_01474 663952.SDD27957_09400 4.2e-12 77.4 Streptococcus dysgalactiae group Bacteria 1M9TI@119603,1TXCR@1239,29RS1@1,30CVR@2,4I6AJ@91061 NA|NA|NA BNPNBKBE_01477 1046629.Ssal_00427 1.6e-103 382.1 Firmicutes Bacteria 1V92M@1239,2AIHW@1,318ZT@2 NA|NA|NA BNPNBKBE_01479 1046629.Ssal_00425 0.0 1343.9 Bacilli clpL ko:K04086 ko00000,ko03110 Bacteria 1TRHP@1239,4HAHZ@91061,COG0542@1,COG0542@2 NA|NA|NA O ATP-dependent Clp protease ATP-binding subunit BNPNBKBE_01480 1046629.Ssal_00423 6.7e-43 179.5 Bacilli yoeB ko:K19158 ko00000,ko01000,ko02048 Bacteria 1VEN0@1239,4HRVW@91061,COG4115@1,COG4115@2 NA|NA|NA S Addiction module toxin, Txe YoeB family BNPNBKBE_01481 1046629.Ssal_00422 7.6e-39 166.0 Bacilli yefM 2.3.1.15 ko:K08591,ko:K19158,ko:K19159 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004,ko02048 Bacteria 1VM12@1239,4HRMU@91061,COG2161@1,COG2161@2 NA|NA|NA D Antitoxin component of a toxin-antitoxin (TA) module BNPNBKBE_01482 435842.HMPREF0848_01254 4.5e-197 693.7 Bacilli ylbM Bacteria 1TPP2@1239,4HAZJ@91061,COG1323@1,COG1323@2 NA|NA|NA S Belongs to the UPF0348 family BNPNBKBE_01483 435842.HMPREF0848_01255 2.2e-139 501.5 Bacilli yqeM Bacteria 1V24K@1239,4HDFY@91061,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase domain protein BNPNBKBE_01484 904306.HMPREF9192_0760 1e-57 229.2 Bacilli rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 ko:K09710 ko00000,ko03009 Bacteria 1VA2Z@1239,4HKEJ@91061,COG0799@1,COG0799@2 NA|NA|NA J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation BNPNBKBE_01485 435842.HMPREF0848_01257 1.1e-86 325.9 Bacilli entB 3.5.1.19 ko:K08281 ko00760,ko01100,map00760,map01100 R01268 RC00100 ko00000,ko00001,ko01000 Bacteria 1VF7P@1239,4HQSB@91061,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family BNPNBKBE_01486 904306.HMPREF9192_0758 3.7e-105 387.5 Bacilli nadD 2.7.6.3,2.7.7.18 ko:K00950,ko:K00969,ko:K06950 ko00760,ko00790,ko01100,map00760,map00790,map01100 M00115,M00126,M00841 R00137,R03005,R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6Y1@1239,4HHRY@91061,COG1713@1,COG1713@2 NA|NA|NA H HD superfamily hydrolase involved in NAD metabolism BNPNBKBE_01487 1046629.Ssal_00417 1e-116 426.0 Bacilli nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1V3SK@1239,4HGXK@91061,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) BNPNBKBE_01488 1046629.Ssal_00416 7.7e-49 199.5 Bacilli yhbY GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 ko:K07574 ko00000,ko03009 Bacteria 1VEGM@1239,4HKC7@91061,COG1534@1,COG1534@2 NA|NA|NA J RNA-binding protein BNPNBKBE_01489 1046629.Ssal_00415 6.6e-212 743.0 Bacilli yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 ko:K06948 ko00000,ko03009 Bacteria 1TPM2@1239,4HAAF@91061,COG1161@1,COG1161@2 NA|NA|NA S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis BNPNBKBE_01490 904306.HMPREF9192_0754 5.1e-98 363.6 Bacilli yqeG ko:K07015 ko00000 Bacteria 1V6KM@1239,4HGAV@91061,COG2179@1,COG2179@2 NA|NA|NA S hydrolase of the HAD superfamily BNPNBKBE_01491 904306.HMPREF9192_0753 5.3e-151 540.4 Bacilli yicL Bacteria 1TR6G@1239,4HAMD@91061,COG0697@1,COG0697@2 NA|NA|NA EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily BNPNBKBE_01492 435842.HMPREF0848_01264 9.3e-65 252.7 Bacilli Bacteria 1VBNR@1239,2B9ZC@1,323D0@2,4HNA3@91061 NA|NA|NA BNPNBKBE_01493 1046629.Ssal_00411 2.3e-273 947.6 Bacilli gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 ko:K01876,ko:K02434 ko00970,ko01100,map00970,map01100 M00359,M00360 R03905,R04212,R05577 RC00010,RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPG3@1239,4HAFB@91061,COG0064@1,COG0064@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) BNPNBKBE_01494 904306.HMPREF9192_0732 1.3e-268 931.8 Bacilli gatA 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 1TP0C@1239,4HBAZ@91061,COG0154@1,COG0154@2 NA|NA|NA J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) BNPNBKBE_01495 1046629.Ssal_00409 1.4e-47 195.3 Bacilli gatC 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 iAF987.Gmet_0076 Bacteria 1VEK3@1239,4HNNA@91061,COG0721@1,COG0721@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) BNPNBKBE_01496 435842.HMPREF0848_01268 9e-233 812.8 Bacilli 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1TR6K@1239,4HGDG@91061,COG0438@1,COG0438@2 NA|NA|NA M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon BNPNBKBE_01497 435842.HMPREF0848_01269 3.8e-187 661.0 Firmicutes Bacteria 1TQZR@1239,COG0438@1,COG0438@2 NA|NA|NA M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1 BNPNBKBE_01498 435842.HMPREF0848_01270 5.7e-158 563.5 Firmicutes Bacteria 1V7WV@1239,COG1216@1,COG1216@2 NA|NA|NA H COG0463 Glycosyltransferases involved in cell wall biogenesis BNPNBKBE_01499 435842.HMPREF0848_01271 5.7e-217 760.0 Bacteria Bacteria COG1442@1,COG1442@2 NA|NA|NA M lipopolysaccharide 3-alpha-galactosyltransferase activity BNPNBKBE_01500 1046629.Ssal_00406 2.2e-292 1010.7 Bacilli ascB 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family BNPNBKBE_01501 322159.STER_1598 4.4e-100 370.5 Bacilli pncA ko:K16788 ko00000,ko02000 2.A.88.5 iSB619.SA_RS09955 Bacteria 1V1CY@1239,4HFRS@91061,COG1335@1,COG1335@2 NA|NA|NA Q isochorismatase BNPNBKBE_01502 1046629.Ssal_00404 8.1e-140 503.1 Bacilli codY GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K03706 ko00000,ko03000 Bacteria 1TS7A@1239,4HA9U@91061,COG4465@1,COG4465@2 NA|NA|NA K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor BNPNBKBE_01503 1046629.Ssal_00403 1.7e-237 828.2 Bacilli alaA GO:0003674,GO:0003824,GO:0004021,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0019842,GO:0030170,GO:0030632,GO:0032787,GO:0033554,GO:0036094,GO:0040007,GO:0042221,GO:0042851,GO:0042852,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0046677,GO:0047635,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.2,2.6.1.66 ko:K00814,ko:K14260 ko00220,ko00250,ko00290,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00220,map00250,map00290,map00710,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00171 R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 iNJ661.Rv0337c Bacteria 1TP0J@1239,4HD83@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase BNPNBKBE_01504 1046629.Ssal_00402 9e-75 286.2 Bacilli XK27_03180 ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1V3NY@1239,4HIP3@91061,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein BNPNBKBE_01506 1046629.Ssal_00399 1.5e-157 562.0 Bacilli pflA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0018307,GO:0019538,GO:0033554,GO:0036211,GO:0043170,GO:0043364,GO:0043365,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070283,GO:0071704,GO:1901564 1.97.1.4 ko:K04069 R04710 ko00000,ko01000 iECOK1_1307.ECOK1_0925,iEcE24377_1341.EcE24377A_0980,iEcSMS35_1347.EcSMS35_2219,iYL1228.KPN_00930 Bacteria 1TPK2@1239,4HACV@91061,COG1180@1,COG1180@2 NA|NA|NA C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine BNPNBKBE_01507 1000570.HMPREF9966_1907 1.4e-08 67.0 Streptococcus anginosus group ko:K06236 ko04151,ko04510,ko04512,ko04611,ko04926,ko04933,ko04974,ko05146,ko05165,map04151,map04510,map04512,map04611,map04926,map04933,map04974,map05146,map05165 ko00000,ko00001,ko00536,ko04516 Bacteria 1UMUJ@1239,42EFA@671232,4IU0F@91061,COG3468@1,COG3468@2 NA|NA|NA MU outer membrane autotransporter barrel domain protein BNPNBKBE_01508 1046629.Ssal_00397 3.2e-237 827.4 Bacilli hlyX ko:K03699 ko00000,ko02042 Bacteria 1TPN0@1239,4H9SB@91061,COG1253@1,COG1253@2 NA|NA|NA S COG1253 Hemolysins and related proteins containing CBS domains BNPNBKBE_01509 1046629.Ssal_00395 1.2e-140 505.8 Bacilli modF GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21,3.6.3.34 ko:K02013,ko:K02028,ko:K05776 ko02010,map02010 M00189,M00236,M00240 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14,3.A.1.3 Bacteria 1TRR4@1239,4HB4U@91061,COG1119@1,COG1119@2 NA|NA|NA P abc transporter atp-binding protein BNPNBKBE_01511 889204.HMPREF9423_0482 1.8e-24 118.6 Streptococcus infantis Bacteria 1TWGT@1239,2DIXP@1,304C0@2,43G7X@68892,4I5A1@91061 NA|NA|NA BNPNBKBE_01513 1046629.Ssal_00394 0.0 1242.3 Bacilli yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 1TR4G@1239,4HBJR@91061,COG0025@1,COG0025@2 NA|NA|NA P NhaP-type Na H and K H antiporters BNPNBKBE_01515 904306.HMPREF9192_0714 3.2e-95 354.4 Bacilli ytqB Bacteria 1UHQD@1239,4HIMC@91061,COG0144@1,COG0144@2 NA|NA|NA J (SAM)-dependent BNPNBKBE_01516 904306.HMPREF9192_0713 1.3e-181 642.1 Bacilli yhcC GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 ko:K07139 ko00000 Bacteria 1TQ57@1239,4H9N8@91061,COG1242@1,COG1242@2 NA|NA|NA S radical SAM protein BNPNBKBE_01517 264199.stu1647 7.1e-187 659.8 Bacilli ylbL ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Bacteria 1TRUF@1239,4HBAY@91061,COG3480@1,COG3480@2 NA|NA|NA T Belongs to the peptidase S16 family BNPNBKBE_01518 1046629.Ssal_00388 1.1e-86 325.9 Bacilli coaD 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3MR@1239,4HH47@91061,COG0669@1,COG0669@2 NA|NA|NA H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate BNPNBKBE_01519 435842.HMPREF0848_01291 1.9e-92 345.1 Bacilli rsmD 2.1.1.171 ko:K08316 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1V3JF@1239,4HGXT@91061,COG0742@1,COG0742@2 NA|NA|NA L Methyltransferase BNPNBKBE_01520 1046629.Ssal_00386 2.1e-171 608.2 Bacilli trxB 1.8.1.9 ko:K00384 ko00450,map00450 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 Bacteria 1TNZS@1239,4HA4N@91061,COG0492@1,COG0492@2 NA|NA|NA C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family BNPNBKBE_01521 1005705.HMPREF9967_0788 5e-10 70.1 Streptococcus infantis Bacteria 1TWHK@1239,2DIY2@1,304CK@2,43GAW@68892,4I5AY@91061 NA|NA|NA S Protein of unknown function (DUF4059) BNPNBKBE_01522 904306.HMPREF9192_0705 6.1e-129 466.8 Bacilli tcyN 3.6.3.21 ko:K02028,ko:K10010,ko:K16960,ko:K16963 ko02010,map02010 M00234,M00236,M00585,M00586 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.10,3.A.1.3.13,3.A.1.3.14 Bacteria 1TNYD@1239,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E abc transporter atp-binding protein BNPNBKBE_01523 264199.stu1653 4e-162 577.4 Bacilli yxeN ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 M00236,M00585,M00586 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.13 Bacteria 1UZ2C@1239,4HF77@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter (Permease BNPNBKBE_01524 1046629.Ssal_00380 1.1e-150 539.3 Bacilli yxeM ko:K02030,ko:K16957 ko02010,map02010 M00236,M00585 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.13 Bacteria 1V7WQ@1239,4HK1Z@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC-type amino acid transport signal transduction systems, periplasmic component domain BNPNBKBE_01525 888049.HMPREF8578_1185 8e-35 154.5 Streptococcus oralis Bacteria 1TWTB@1239,1WP3D@1303,2DJ1D@1,304JE@2,4I5MI@91061 NA|NA|NA BNPNBKBE_01526 904306.HMPREF9192_0701 2.8e-202 711.1 Bacilli dinB GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031668,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 ko:K02346 ko00000,ko01000,ko03400 Bacteria 1TP42@1239,4HADJ@91061,COG0389@1,COG0389@2 NA|NA|NA L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII BNPNBKBE_01527 1046629.Ssal_00375 0.0 1567.0 Bacilli pflB 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 Bacteria 1TPTF@1239,4H9RD@91061,COG1882@1,COG1882@2 NA|NA|NA C formate acetyltransferase' BNPNBKBE_01528 1046629.Ssal_00372 3.3e-141 507.7 Bacilli cah 4.2.1.1 ko:K01674 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 Bacteria 1V16J@1239,4HA62@91061,COG3338@1,COG3338@2 NA|NA|NA P carbonic anhydrase BNPNBKBE_01529 322159.STER_1624 5.4e-72 276.9 Bacilli yjcF ko:K02348 ko00000 Bacteria 1VA2J@1239,4HKF5@91061,COG2153@1,COG2153@2 NA|NA|NA S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases BNPNBKBE_01531 1046629.Ssal_00368 4.3e-172 610.5 Bacilli ampC Bacteria 1TNZX@1239,4IPJT@91061,COG1680@1,COG1680@2 NA|NA|NA V COG1680 Beta-lactamase class C and other penicillin binding proteins BNPNBKBE_01532 1046629.Ssal_00367 1.4e-136 492.3 Bacilli cppA Bacteria 1VMPM@1239,4HSVM@91061,COG0346@1,COG0346@2 NA|NA|NA E CppA N-terminal BNPNBKBE_01533 1046629.Ssal_00366 1.8e-95 355.5 Bacteria ko:K07052 ko00000 Bacteria COG1266@1,COG1266@2 NA|NA|NA V CAAX protease self-immunity BNPNBKBE_01534 1046629.Ssal_00365 4.7e-149 533.9 Bacilli gla ko:K02440 ko00000,ko02000 1.A.8.1,1.A.8.2 Bacteria 1TP4T@1239,4HE39@91061,COG0580@1,COG0580@2 NA|NA|NA U Belongs to the MIP aquaporin (TC 1.A.8) family BNPNBKBE_01535 1046629.Ssal_00364 0.0 1476.8 Bacilli pepX 3.4.14.11 ko:K01281 ko00000,ko01000,ko01002 Bacteria 1TT78@1239,4HBA0@91061,COG2936@1,COG2936@2 NA|NA|NA E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline BNPNBKBE_01539 322159.STER_1636 1.8e-44 184.9 Bacteria spiA ko:K18831 ko00000,ko02048,ko03000 Bacteria COG1476@1,COG1476@2 NA|NA|NA K sequence-specific DNA binding BNPNBKBE_01547 435842.HMPREF0848_01339 0.0 1084.3 Bacilli mdlB GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008144,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0033036,GO:0034040,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K06147,ko:K18890 ko02010,map02010 M00707 ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_01548 1046629.Ssal_00350 0.0 1100.1 Bacilli mdlA GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016021,GO:0017076,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K06148,ko:K18889 ko02010,map02010 M00707 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 Bacteria 1TP0B@1239,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_01551 1046629.Ssal_00348 9.7e-89 332.8 Bacilli XK27_09885 Bacteria 1VKIA@1239,4HQZW@91061,COG4767@1,COG4767@2 NA|NA|NA V Glycopeptide antibiotics resistance protein BNPNBKBE_01552 1046629.Ssal_00347 1.8e-223 781.6 Bacilli rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 ko00000,ko01000,ko03009 Bacteria 1TPVF@1239,4H9NU@91061,COG0820@1,COG0820@2 NA|NA|NA J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs BNPNBKBE_01553 435842.HMPREF0848_01344 5.6e-63 247.7 Bacilli yutD Bacteria 1VA85@1239,4HKF7@91061,COG4470@1,COG4470@2 NA|NA|NA J protein conserved in bacteria BNPNBKBE_01554 1046629.Ssal_00344 3.1e-259 900.6 Bacilli yunD 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 1TQCW@1239,4HAUC@91061,COG0737@1,COG0737@2 NA|NA|NA F Belongs to the 5'-nucleotidase family BNPNBKBE_01555 1046629.Ssal_00342 3.7e-220 770.8 Bacilli cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TPAP@1239,4HA98@91061,COG0513@1,COG0513@2 NA|NA|NA JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures BNPNBKBE_01556 1046629.Ssal_00341 1.2e-183 649.0 Bacilli mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Bacteria 1TP8W@1239,4H9TP@91061,COG0472@1,COG0472@2 NA|NA|NA M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan BNPNBKBE_01557 435842.HMPREF0848_01353 0.0 1402.5 Bacilli ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 1TP93@1239,4H9VQ@91061,COG0768@1,COG0768@2 NA|NA|NA M penicillin-binding protein BNPNBKBE_01558 435842.HMPREF0848_01354 2.4e-45 188.0 Bacilli ftsL Bacteria 1VCE5@1239,4HM4W@91061,COG4839@1,COG4839@2 NA|NA|NA D cell division protein FtsL BNPNBKBE_01559 322159.STER_1668 5.7e-172 610.1 Bacilli rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 1TNZV@1239,4H9U2@91061,COG0275@1,COG0275@2 NA|NA|NA J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA BNPNBKBE_01560 264199.stu1704 7.9e-90 337.4 Bacilli Bacteria 1W5UA@1239,2DDKD@1,2ZIF1@2,4HZND@91061 NA|NA|NA BNPNBKBE_01562 1046629.Ssal_00333 1.3e-45 189.1 Bacilli yhaI Bacteria 1V90R@1239,4HQ7Q@91061,COG3152@1,COG3152@2 NA|NA|NA J Protein of unknown function (DUF805) BNPNBKBE_01563 435842.HMPREF0848_01358 3.4e-62 244.2 Bacilli yhaI Bacteria 1V90R@1239,4HQ7Q@91061,COG3152@1,COG3152@2 NA|NA|NA J Protein of unknown function (DUF805) BNPNBKBE_01564 435842.HMPREF0848_01358 2.3e-32 145.2 Bacilli yhaI Bacteria 1V90R@1239,4HQ7Q@91061,COG3152@1,COG3152@2 NA|NA|NA J Protein of unknown function (DUF805) BNPNBKBE_01565 435842.HMPREF0848_01359 3.2e-60 237.7 Firmicutes yhaI Bacteria 1V90R@1239,COG3152@1,COG3152@2 NA|NA|NA J Membrane BNPNBKBE_01566 904306.HMPREF9192_0660 4.6e-222 776.9 Bacilli proA GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iLJ478.TM0293,iYL1228.KPN_00280,iYO844.BSU13130 Bacteria 1TQ9V@1239,4HB7B@91061,COG0014@1,COG0014@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate BNPNBKBE_01567 904306.HMPREF9192_0659 2.6e-141 508.1 Bacilli proB GO:0003674,GO:0003824,GO:0004349,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016772,GO:0016774,GO:0016903,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPG6@1239,4HA9B@91061,COG0263@1,COG0263@2 NA|NA|NA E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate BNPNBKBE_01568 1046629.Ssal_00329 3.2e-284 983.8 Bacilli XK27_00765 ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TSZA@1239,28MBB@1,2ZAPV@2,4HDKH@91061 NA|NA|NA BNPNBKBE_01569 1046629.Ssal_00328 8.1e-134 483.0 Bacilli ecsA_2 ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQIH@1239,4HCEU@91061,COG1131@1,COG1131@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_01570 1046629.Ssal_00327 3.6e-126 457.6 Bacilli ko:K07150 ko00000 Bacteria 1TQWV@1239,4HEYY@91061,COG1811@1,COG1811@2 NA|NA|NA S Protein of unknown function (DUF554) BNPNBKBE_01571 1046629.Ssal_00325 0.0 2321.2 Bacilli addA 3.6.4.12 ko:K16898 ko00000,ko01000,ko03400 Bacteria 1TQ35@1239,4HA64@91061,COG1074@1,COG1074@2 NA|NA|NA L ATP-dependent helicase nuclease subunit A BNPNBKBE_01572 1046629.Ssal_00322 0.0 2116.3 Bacilli rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.3,3.6.4.12 ko:K01153,ko:K16899 ko00000,ko01000,ko02048,ko03400 Bacteria 1TQJW@1239,4HAY6@91061,COG3857@1,COG3857@2 NA|NA|NA L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination BNPNBKBE_01573 1046629.Ssal_00321 8.3e-233 812.8 Bacteria 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria COG3290@1,COG3290@2 NA|NA|NA T protein histidine kinase activity BNPNBKBE_01574 1046629.Ssal_00320 5e-227 793.5 Bacteria dcuS GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016020,GO:0016021,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031323,GO:0031326,GO:0035556,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051259,GO:0051260,GO:0051716,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141 2.7.13.3 ko:K02476,ko:K07701,ko:K07706,ko:K11614 ko02020,ko02024,map02020,map02024 M00488,M00490,M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria COG3290@1,COG3290@2 NA|NA|NA T protein histidine kinase activity BNPNBKBE_01575 365659.smi_1723 1.5e-13 84.7 Streptococcus mitis Bacteria 1U4TK@1239,2DKFM@1,2TQA8@28037,309CC@2,4IEJ2@91061 NA|NA|NA BNPNBKBE_01578 1046629.Ssal_00316 5.8e-146 523.5 Firmicutes GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030312,GO:0031224,GO:0042623,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 ko:K01990,ko:K21397 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V0ED@1239,COG1131@1,COG1131@2 NA|NA|NA V Psort location CytoplasmicMembrane, score BNPNBKBE_01580 1046629.Ssal_00314 1.7e-298 1031.2 Firmicutes ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 1TSUC@1239,COG0443@1,COG0443@2 NA|NA|NA O MreB/Mbl protein BNPNBKBE_01581 889204.HMPREF9423_1919 4.7e-196 690.3 Streptococcus infantis mccF Bacteria 1TRBB@1239,43FE2@68892,4HDUZ@91061,COG1619@1,COG1619@2 NA|NA|NA V the current gene model (or a revised gene model) may contain a frame shift BNPNBKBE_01582 435842.HMPREF0848_01376 4e-43 180.3 Bacilli ko:K15383 ko00000,ko02000 9.A.58.2 Bacteria 1VCDB@1239,4HX7U@91061,COG4095@1,COG4095@2 NA|NA|NA S Sugar efflux transporter for intercellular exchange BNPNBKBE_01583 435842.HMPREF0848_01375 6.2e-76 290.0 Bacilli mccF Bacteria 1TRBB@1239,4HDUZ@91061,COG1619@1,COG1619@2 NA|NA|NA V LD-carboxypeptidase BNPNBKBE_01584 322159.STER_1683 4.8e-120 437.2 Bacilli liaI ko:K11619 ko02020,map02020 M00754 ko00000,ko00001,ko00002 Bacteria 1VGSF@1239,4IRBC@91061,COG4758@1,COG4758@2 NA|NA|NA S membrane BNPNBKBE_01585 322159.STER_1684 1.5e-74 285.4 Bacilli XK27_02470 Bacteria 1VBF7@1239,4HMZX@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain BNPNBKBE_01586 1046629.Ssal_00311 4.5e-308 1063.1 Bacteria Bacteria COG4640@1,COG4640@2 NA|NA|NA KT response to antibiotic BNPNBKBE_01587 1046629.Ssal_00310 1.7e-112 412.9 Bacilli yebC ko:K16637 ko00000,ko02042 Bacteria 1VK5M@1239,4HS44@91061,COG3064@1,COG3064@2 NA|NA|NA M Membrane BNPNBKBE_01588 904306.HMPREF9192_0643 6.8e-259 899.4 Bacilli XK27_03190 ko:K16785 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TSZZ@1239,4HB54@91061,COG0561@1,COG0561@2,COG4696@1,COG4696@2 NA|NA|NA S hydrolases of the HAD superfamily BNPNBKBE_01589 1046629.Ssal_00308 1e-176 625.9 Bacilli ansA 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 R00485 RC00010,RC02798 ko00000,ko00001,ko01000 Bacteria 1TPP9@1239,4H9YJ@91061,COG0252@1,COG0252@2 NA|NA|NA EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D BNPNBKBE_01591 322159.STER_1693 1.4e-156 558.9 Bacilli Bacteria 1VIH9@1239,4HQ23@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins BNPNBKBE_01592 322159.STER_1694 2.9e-277 960.7 Firmicutes ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1VBVE@1239,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region BNPNBKBE_01593 1046629.Ssal_00306 3.2e-30 137.1 Firmicutes yozG ko:K07727 ko00000,ko03000 Bacteria 1VESP@1239,COG3655@1,COG3655@2 NA|NA|NA K Transcriptional regulator BNPNBKBE_01597 435842.HMPREF0848_01388 0.0 1308.9 Bacilli recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TQ6I@1239,4HAWN@91061,COG1200@1,COG1200@2 NA|NA|NA L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) BNPNBKBE_01598 1046629.Ssal_00297 3.2e-182 644.4 Bacilli alr 5.1.1.1,5.1.1.5 ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011 Bacteria 1TNYY@1239,4HA95@91061,COG0787@1,COG0787@2 NA|NA|NA E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids BNPNBKBE_01599 1046629.Ssal_00296 1.7e-60 238.4 Bacilli acpS 2.7.6.3,2.7.8.7,5.1.1.1 ko:K00950,ko:K00997,ko:K01775 ko00473,ko00770,ko00790,ko01100,ko01502,map00473,map00770,map00790,map01100,map01502 M00126,M00841 R00401,R01625,R03503 RC00002,RC00017,RC00285 ko00000,ko00001,ko00002,ko01000,ko01011 iYO844.BSU04620 Bacteria 1VA0T@1239,4HKBI@91061,COG0736@1,COG0736@2 NA|NA|NA I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein BNPNBKBE_01600 1046629.Ssal_00295 2.8e-196 691.0 Firmicutes aroF 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS07240 Bacteria 1TQI4@1239,COG0722@1,COG0722@2 NA|NA|NA E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) BNPNBKBE_01601 904306.HMPREF9192_0634 5.5e-197 693.3 Firmicutes aroF 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS07240 Bacteria 1TQI4@1239,COG0722@1,COG0722@2 NA|NA|NA E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) BNPNBKBE_01602 1046629.Ssal_00292 0.0 1657.1 Bacilli secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1TPEY@1239,4HA22@91061,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane BNPNBKBE_01604 1046629.Ssal_00290 1.9e-188 664.8 Bacilli manA 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 1VRGI@1239,4HBFW@91061,COG1482@1,COG1482@2 NA|NA|NA G mannose-6-phosphate isomerase BNPNBKBE_01605 1046629.Ssal_00289 7.2e-169 599.7 Bacilli scrK 2.7.1.2,2.7.1.4 ko:K00845,ko:K00847 ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R00760,R00867,R01600,R01786,R03920 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQU4@1239,4HA1C@91061,COG1940@1,COG1940@2 NA|NA|NA GK Fructokinase BNPNBKBE_01606 1046629.Ssal_00287 0.0 1201.0 Bacilli scrA 2.7.1.201,2.7.1.208,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810,ko:K02817,ko:K02818,ko:K02819,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00269,M00270,M00271,M00272,M00303,M00806 R00811,R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.13,4.A.1.2.2,4.A.1.2.4,4.A.1.2.5,4.A.1.2.6,4.A.1.2.8,4.A.1.2.9 Bacteria 1TP5X@1239,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G pts system BNPNBKBE_01607 1046629.Ssal_00286 2.7e-290 1003.8 Bacilli scrB 3.2.1.26,3.2.1.80 ko:K01193,ko:K03332 ko00051,ko00052,ko00500,ko01100,map00051,map00052,map00500,map01100 R00801,R00802,R00879,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 GH32 Bacteria 1TPAE@1239,4H9Y7@91061,COG1621@1,COG1621@2 NA|NA|NA G invertase BNPNBKBE_01608 435842.HMPREF0848_01398 1.1e-178 632.5 Firmicutes scrR ko:K02529,ko:K03484 ko00000,ko03000 Bacteria 1TQ7K@1239,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator BNPNBKBE_01609 1046629.Ssal_00284 1.3e-70 272.3 Bacilli nusB ko:K03625 ko00000,ko03009,ko03021 Bacteria 1VA9B@1239,4HKMU@91061,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons BNPNBKBE_01610 1046629.Ssal_00283 1.7e-61 241.9 Bacilli yqhY ko:K10947 ko00000,ko03000 Bacteria 1V4IC@1239,4HJ7T@91061,COG1302@1,COG1302@2 NA|NA|NA S protein conserved in bacteria BNPNBKBE_01611 904306.HMPREF9192_0624 7.1e-98 363.2 Bacilli efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 1TR8P@1239,4H9YX@91061,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase BNPNBKBE_01612 1046629.Ssal_00281 3.3e-85 320.9 Bacilli comEB 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 Bacteria 1V8V0@1239,4IQZA@91061,COG2131@1,COG2131@2 NA|NA|NA F ComE operon protein 2 BNPNBKBE_01613 1046629.Ssal_00280 5.4e-187 660.2 Bacilli pepP GO:0003674,GO:0003824,GO:0004177,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271,ko:K08326 ko00000,ko01000,ko01002 Bacteria 1TQ44@1239,4HAT7@91061,COG0006@1,COG0006@2 NA|NA|NA E Belongs to the peptidase M24B family BNPNBKBE_01615 904306.HMPREF9192_0620 1.8e-145 521.9 Firmicutes ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPBQ@1239,COG1131@1,COG1131@2 NA|NA|NA V 'abc transporter, ATP-binding protein BNPNBKBE_01622 1046629.Ssal_00276 0.0 1870.5 Bacilli uvrA ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TPIJ@1239,4HAW9@91061,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate BNPNBKBE_01623 435842.HMPREF0848_01411 1.2e-166 592.4 Bacilli corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1TPI8@1239,4HE7S@91061,COG0598@1,COG0598@2 NA|NA|NA P COG0598 Mg2 and Co2 transporters BNPNBKBE_01624 1046629.Ssal_00273 7.2e-121 439.9 Bacilli XK27_01040 Bacteria 1VF5N@1239,4HMVT@91061,COG4858@1,COG4858@2 NA|NA|NA S Protein of unknown function (DUF1129) BNPNBKBE_01626 1046629.Ssal_00271 1.7e-35 154.8 Bacilli rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963,ko:K03111,ko:K15125 ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133 M00178 br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400 Bacteria 1V9XS@1239,4HKCC@91061,COG0238@1,COG0238@2 NA|NA|NA J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit BNPNBKBE_01627 904306.HMPREF9192_0609 2.5e-81 308.1 Bacilli ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 1V3WT@1239,4HH8I@91061,COG0629@1,COG0629@2 NA|NA|NA L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism BNPNBKBE_01628 904306.HMPREF9192_0608 1.1e-46 192.2 Bacilli rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 ko:K02990 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VA18@1239,4HKHD@91061,COG0360@1,COG0360@2 NA|NA|NA J Binds together with S18 to 16S ribosomal RNA BNPNBKBE_01629 1214166.ALLG01000021_gene137 5.5e-42 178.3 Streptococcus suis XK27_05745 Bacteria 1U8WY@1239,1WSBS@1307,2BJFN@1,32DS8@2,4IIVI@91061 NA|NA|NA BNPNBKBE_01632 1046629.Ssal_01817 1.1e-162 579.3 Bacilli ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1TPH6@1239,4H9T8@91061,COG1227@1,COG1227@2 NA|NA|NA C inorganic pyrophosphatase BNPNBKBE_01633 1046629.Ssal_01816 2.8e-103 381.3 Bacilli Bacteria 1W4V4@1239,2F8BM@1,340QP@2,4HR72@91061 NA|NA|NA S Domain of unknown function (DUF1803) BNPNBKBE_01634 1046629.Ssal_01815 7.8e-102 376.3 Bacilli ygaC ko:K07586 ko00000 Bacteria 1TRX8@1239,4H9NM@91061,COG3557@1,COG3557@2 NA|NA|NA J Belongs to the UPF0374 family BNPNBKBE_01635 1046629.Ssal_01814 2e-135 488.4 Bacilli recX GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496 2.4.1.337 ko:K03565,ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003,ko03400 GT4 Bacteria 1V72V@1239,4HKE3@91061,COG2137@1,COG2137@2 NA|NA|NA S Regulatory protein RecX BNPNBKBE_01636 1046629.Ssal_01813 2.6e-247 860.9 Bacilli rumA 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 ko00000,ko01000,ko03009,ko03016 Bacteria 1TP4H@1239,4HA6M@91061,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family BNPNBKBE_01637 1046629.Ssal_01812 1.4e-192 678.7 Bacilli asnA GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 R00483 RC00010 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299 Bacteria 1TP28@1239,4HAEC@91061,COG2502@1,COG2502@2 NA|NA|NA E aspartate--ammonia ligase BNPNBKBE_01638 1046629.Ssal_01811 8.2e-257 892.5 Bacilli lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iYO844.BSU03790 Bacteria 1TPQJ@1239,4HAEP@91061,COG0527@1,COG0527@2 NA|NA|NA E Belongs to the aspartokinase family BNPNBKBE_01639 1046629.Ssal_01810 2.8e-114 417.9 Bacilli Bacteria 1VA1U@1239,4HMKX@91061,COG0637@1,COG0637@2 NA|NA|NA S HAD hydrolase, family IA, variant 3 BNPNBKBE_01640 1046629.Ssal_01809 4.8e-140 503.8 Bacilli phaB GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006635,GO:0006636,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016053,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033559,GO:0034017,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:0072330,GO:1901575,GO:1901576 5.3.3.14,5.3.3.18 ko:K15866,ko:K18474 ko00061,ko00360,ko01120,map00061,map00360,map01120 R07639,R09837,R09839 RC00004,RC00326,RC01078,RC02689,RC03003 ko00000,ko00001,ko01000,ko01004 Bacteria 1TQ2V@1239,4HBT0@91061,COG1024@1,COG1024@2 NA|NA|NA I Belongs to the enoyl-CoA hydratase isomerase family BNPNBKBE_01641 1046629.Ssal_01808 5.2e-72 276.9 Bacilli marR Bacteria 1V6GY@1239,4HIMR@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator, MarR family BNPNBKBE_01642 1046629.Ssal_01807 1.4e-170 605.5 Bacilli fabH 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TP0K@1239,4HATK@91061,COG0332@1,COG0332@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids BNPNBKBE_01643 1046629.Ssal_01806 3.3e-30 137.1 Bacilli acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 1VGIY@1239,4HP0V@91061,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis BNPNBKBE_01644 1046629.Ssal_01805 9.9e-172 609.4 Bacilli fabK 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 iHN637.CLJU_RS20775 Bacteria 1TPC3@1239,4H9T0@91061,COG2070@1,COG2070@2 NA|NA|NA S 2-Nitropropane dioxygenase BNPNBKBE_01645 1046629.Ssal_01804 6.7e-162 576.6 Bacilli fabD 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPB7@1239,4HBCU@91061,COG0331@1,COG0331@2 NA|NA|NA I Malonyl CoA-acyl carrier protein transacylase BNPNBKBE_01646 904306.HMPREF9192_0291 8.1e-126 456.4 Bacilli Bacteria 1TP76@1239,4HAA6@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase BNPNBKBE_01647 1046629.Ssal_01802 2.6e-233 814.3 Bacilli fabF 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPA7@1239,4H9SD@91061,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP BNPNBKBE_01648 322159.STER_0435 9.4e-54 216.5 Bacilli accB 2.3.1.12,4.1.1.3 ko:K00627,ko:K01571,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00217,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 Bacteria 1VAB7@1239,4HKCS@91061,COG0511@1,COG0511@2 NA|NA|NA I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA BNPNBKBE_01649 1046629.Ssal_01800 1.5e-71 275.4 Bacilli fabZ 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 1V6EX@1239,4HGX1@91061,COG0764@1,COG0764@2 NA|NA|NA I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs BNPNBKBE_01650 1046629.Ssal_01798 3.5e-255 887.1 Bacilli accC GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iSF_1195.SF3294 Bacteria 1TP16@1239,4HARK@91061,COG0439@1,COG0439@2 NA|NA|NA I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism BNPNBKBE_01651 1046629.Ssal_01797 3.9e-159 567.4 Bacilli accD 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4U@1239,4HAI7@91061,COG0777@1,COG0777@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA BNPNBKBE_01652 1046629.Ssal_01796 1.8e-139 501.9 Bacilli accA 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHNS@1239,4HA4C@91061,COG0825@1,COG0825@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA BNPNBKBE_01653 1046629.Ssal_01795 4.7e-90 337.0 Bacilli luxS GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300 Bacteria 1V1V3@1239,4HFR0@91061,COG1854@1,COG1854@2 NA|NA|NA H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) BNPNBKBE_01654 904306.HMPREF9192_0315 1.2e-206 726.1 Bacilli rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K05802,ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko02000,ko03019 1.A.23.1.1 Bacteria 1TP48@1239,4HC9J@91061,COG1418@1,COG1418@2,COG4372@1,COG4372@2 NA|NA|NA D Endoribonuclease that initiates mRNA decay BNPNBKBE_01655 904306.HMPREF9192_0316 3.1e-125 454.5 Bacilli fruR ko:K03436 ko00000,ko03000 Bacteria 1TSF8@1239,4HDT9@91061,COG1349@1,COG1349@2 NA|NA|NA K transcriptional BNPNBKBE_01656 1046629.Ssal_01792 7.6e-166 589.7 Bacilli pfkB 2.7.1.11,2.7.1.56 ko:K00882,ko:K16370 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00345 R00756,R02071,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ36@1239,4HANU@91061,COG1105@1,COG1105@2 NA|NA|NA H Belongs to the carbohydrate kinase PfkB family. LacC subfamily BNPNBKBE_01657 1046629.Ssal_01791 0.0 1165.2 Bacilli fruA 2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02806 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 Bacteria 1TPKU@1239,4H9KR@91061,COG1299@1,COG1299@2,COG1445@1,COG1445@2,COG1762@1,COG1762@2 NA|NA|NA G phosphotransferase system BNPNBKBE_01658 435842.HMPREF0848_00027 2.8e-257 894.0 Bacilli gor GO:0000166,GO:0003674,GO:0003824,GO:0004362,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071949,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 iZ_1308.Z4900 Bacteria 1TQFH@1239,4HCT8@91061,COG1249@1,COG1249@2 NA|NA|NA C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family BNPNBKBE_01659 1046629.Ssal_00087 6.8e-153 546.6 Bacilli rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02886 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TP9X@1239,4HAE8@91061,COG0090@1,COG0090@2 NA|NA|NA J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity BNPNBKBE_01660 264199.stu1932 2.4e-44 184.5 Bacilli rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02892 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VA4W@1239,4HKCV@91061,COG0089@1,COG0089@2 NA|NA|NA J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome BNPNBKBE_01661 1046629.Ssal_00085 5.7e-104 383.6 Bacilli rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02926,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPGW@1239,4HB01@91061,COG0088@1,COG0088@2 NA|NA|NA J Forms part of the polypeptide exit tunnel BNPNBKBE_01662 1046629.Ssal_00084 2.4e-110 404.8 Bacilli rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 ko:K02906 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPFT@1239,4HAEN@91061,COG0087@1,COG0087@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit BNPNBKBE_01663 1046629.Ssal_00083 2.9e-48 197.6 Bacilli rpsJ GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 ko:K02946 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6C9@1239,4HIKH@91061,COG0051@1,COG0051@2 NA|NA|NA J Involved in the binding of tRNA to the ribosomes BNPNBKBE_01664 1046629.Ssal_00081 1e-187 662.5 Bacilli ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TR47@1239,4HBMW@91061,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing BNPNBKBE_01665 1046629.Ssal_00080 0.0 1154.8 Bacilli XK27_09800 Bacteria 1U6DU@1239,4H9XT@91061,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase BNPNBKBE_01666 1046629.Ssal_00079 2.8e-35 154.8 Firmicutes XK27_09805 Bacteria 1TRNW@1239,COG4642@1,COG4642@2 NA|NA|NA S MORN repeat protein BNPNBKBE_01667 1046629.Ssal_00078 1.4e-80 305.4 Bacilli ptpA 3.1.3.48 ko:K01104,ko:K20945 ko05111,map05111 ko00000,ko00001,ko01000 Bacteria 1V6SG@1239,4HIZN@91061,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family BNPNBKBE_01668 1046629.Ssal_00077 4.1e-250 870.2 Bacilli purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ4C@1239,4H9YT@91061,COG0104@1,COG0104@2 NA|NA|NA F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP BNPNBKBE_01669 1046629.Ssal_00076 2.9e-90 337.8 Bacilli adk 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1V7AW@1239,4HH8A@91061,COG0563@1,COG0563@2 NA|NA|NA F topology modulation protein BNPNBKBE_01671 1046629.Ssal_00070 8.2e-235 819.3 Bacilli rarA ko:K07478 ko00000 Bacteria 1TPVV@1239,4HAIS@91061,COG2256@1,COG2256@2 NA|NA|NA L ATPase related to the helicase subunit of the Holliday junction resolvase BNPNBKBE_01672 1046629.Ssal_00069 8.4e-27 125.6 Bacilli rpmB GO:0003674,GO:0003735,GO:0005198 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEI2@1239,4HNIK@91061,COG0227@1,COG0227@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL28 family BNPNBKBE_01673 1046629.Ssal_00068 6.3e-44 183.0 Bacilli yrzL Bacteria 1VAC4@1239,4HKD0@91061,COG4472@1,COG4472@2 NA|NA|NA S Belongs to the UPF0297 family BNPNBKBE_01674 435842.HMPREF0848_01740 1.8e-69 268.5 Bacilli yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07447 ko00000,ko01000 Bacteria 1V6ER@1239,4HH04@91061,COG0816@1,COG0816@2 NA|NA|NA L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA BNPNBKBE_01675 1046629.Ssal_00066 3.2e-44 184.1 Bacilli yrzB Bacteria 1VAPW@1239,4HKV7@91061,COG3906@1,COG3906@2 NA|NA|NA S Belongs to the UPF0473 family BNPNBKBE_01676 1046629.Ssal_00065 1.3e-288 998.4 Bacilli ccs Bacteria 1V9D8@1239,2F2IJ@1,33VFI@2,4HS77@91061 NA|NA|NA S the current gene model (or a revised gene model) may contain a frame shift BNPNBKBE_01677 1046629.Ssal_00064 0.0 1490.3 Bacilli nrdD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019001,GO:0019103,GO:0019438,GO:0019637,GO:0019692,GO:0030554,GO:0031250,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032556,GO:0032558,GO:0032559,GO:0032560,GO:0032564,GO:0032567,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0046872,GO:0046914,GO:0051065,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_4713,iPC815.YPO3454 Bacteria 1TR9K@1239,4HBIY@91061,COG1327@1,COG1327@2,COG1328@1,COG1328@2 NA|NA|NA F Ribonucleoside-triphosphate reductase BNPNBKBE_01678 435842.HMPREF0848_01736 7.5e-14 82.0 Bacilli Bacteria 1TXD1@1239,2DEKJ@1,2ZNBP@2,4HZYT@91061 NA|NA|NA BNPNBKBE_01679 904306.HMPREF9192_1930 7.3e-86 323.2 Bacilli XK27_10930 Bacteria 1V1C4@1239,4HG6C@91061,COG3981@1,COG3981@2 NA|NA|NA K acetyltransferase BNPNBKBE_01680 1046629.Ssal_00061 1.5e-114 418.7 Bacilli nrdG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0031250,GO:0032991,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 1.97.1.4 ko:K04068 R04710 ko00000,ko01000 iE2348C_1286.E2348C_4563 Bacteria 1V1HG@1239,4HGJ9@91061,COG0602@1,COG0602@2 NA|NA|NA O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine BNPNBKBE_01681 1046629.Ssal_00060 6.9e-119 433.3 Bacilli yaaA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 ko:K09861 ko00000 Bacteria 1TR33@1239,4HFN2@91061,COG3022@1,COG3022@2 NA|NA|NA S Belongs to the UPF0246 family BNPNBKBE_01682 904306.HMPREF9192_1927 3.5e-166 590.9 Bacilli XK27_01785 Bacteria 1TRBT@1239,4HBPR@91061,COG1284@1,COG1284@2 NA|NA|NA S cog cog1284 BNPNBKBE_01683 1046629.Ssal_00058 0.0 1136.3 Bacilli aspS 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPCN@1239,4HACD@91061,COG0173@1,COG0173@2 NA|NA|NA J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) BNPNBKBE_01685 1046629.Ssal_00055 8e-238 829.3 Bacilli hisS 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP3D@1239,4HAM2@91061,COG0124@1,COG0124@2 NA|NA|NA J histidyl-tRNA synthetase BNPNBKBE_01686 1046629.Ssal_00054 3.9e-73 280.8 Bacilli 2.7.1.201,2.7.1.208,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810,ko:K02817,ko:K02818,ko:K02819,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00269,M00270,M00271,M00272,M00303,M00806 R00811,R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.13,4.A.1.2.2,4.A.1.2.4,4.A.1.2.5,4.A.1.2.6,4.A.1.2.8,4.A.1.2.9 Bacteria 1TP5X@1239,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2 NA|NA|NA G pts system BNPNBKBE_01687 1046629.Ssal_00054 5.8e-50 203.4 Bacilli 2.7.1.201,2.7.1.208,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810,ko:K02817,ko:K02818,ko:K02819,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00269,M00270,M00271,M00272,M00303,M00806 R00811,R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.13,4.A.1.2.2,4.A.1.2.4,4.A.1.2.5,4.A.1.2.6,4.A.1.2.8,4.A.1.2.9 Bacteria 1TP5X@1239,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2 NA|NA|NA G pts system BNPNBKBE_01688 1046629.Ssal_00054 8e-08 62.0 Bacilli 2.7.1.201,2.7.1.208,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810,ko:K02817,ko:K02818,ko:K02819,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00269,M00270,M00271,M00272,M00303,M00806 R00811,R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.13,4.A.1.2.2,4.A.1.2.4,4.A.1.2.5,4.A.1.2.6,4.A.1.2.8,4.A.1.2.9 Bacteria 1TP5X@1239,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2 NA|NA|NA G pts system BNPNBKBE_01689 1046629.Ssal_00053 1.2e-218 765.4 Bacilli metE 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPDQ@1239,4HADW@91061,COG0620@1,COG0620@2 NA|NA|NA E Methionine synthase BNPNBKBE_01690 1046629.Ssal_00052 3.4e-25 120.2 Bacilli rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VKMZ@1239,4HR2Q@91061,COG0333@1,COG0333@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL32 family BNPNBKBE_01691 999425.HMPREF9186_00339 0.0 1263.4 Bacilli htaA 3.4.21.72 ko:K01347,ko:K14194 ko05150,map05150 ko00000,ko00001,ko01000,ko01002,ko02000,ko02044 1.B.12.3 Bacteria 1TV1Y@1239,4HBHJ@91061,COG2373@1,COG2373@2,COG4886@1,COG4886@2 NA|NA|NA Q the current gene model (or a revised gene model) may contain a frame shift BNPNBKBE_01692 1095738.HMPREF1047_0924 1.7e-18 98.2 Streptococcus oralis Bacteria 1TWZ1@1239,1WPY9@1303,2DJ35@1,304P3@2,4I5TZ@91061 NA|NA|NA S Domain of unknown function (DUF4649) BNPNBKBE_01693 1046629.Ssal_01265 2.4e-176 624.8 Bacilli XK27_08835 ko:K01989,ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPB0@1239,4HE7G@91061,COG2984@1,COG2984@2 NA|NA|NA S ABC transporter substrate binding protein BNPNBKBE_01694 1046629.Ssal_01264 2.6e-147 528.1 Bacilli XK27_08840 ko:K01989,ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPDJ@1239,4HBMY@91061,COG4120@1,COG4120@2 NA|NA|NA S Belongs to the binding-protein-dependent transport system permease family BNPNBKBE_01695 1046629.Ssal_01263 8.9e-136 489.6 Bacilli XK27_08845 ko:K05833 M00247 ko00000,ko00002,ko02000 Bacteria 1TPAN@1239,4HCHC@91061,COG1101@1,COG1101@2 NA|NA|NA S abc transporter atp-binding protein BNPNBKBE_01696 1046629.Ssal_01262 7.8e-310 1068.9 Bacilli rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TQ9G@1239,4HAAP@91061,COG0595@1,COG0595@2 NA|NA|NA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay BNPNBKBE_01697 1046629.Ssal_01260 9.5e-149 532.7 Bacilli estA ko:K03930 ko00000,ko01000 CE1 Bacteria 1TPA9@1239,4HD64@91061,COG0627@1,COG0627@2 NA|NA|NA S Esterase BNPNBKBE_01698 1046629.Ssal_01259 4.7e-126 457.2 Bacilli XK27_08875 Bacteria 1VW9X@1239,4HWF8@91061,COG5549@1,COG5549@2 NA|NA|NA O Zinc-dependent metalloprotease BNPNBKBE_01699 1214166.ALLG01000018_gene972 1.3e-18 99.4 Streptococcus suis XK27_08880 Bacteria 1U92D@1239,1WTJN@1307,29R1H@1,30C2M@2,4IJ2X@91061 NA|NA|NA BNPNBKBE_01700 435842.HMPREF0848_00535 1e-75 289.3 Bacilli fld ko:K03839 ko00000 Bacteria 1V7AG@1239,4HMJF@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin BNPNBKBE_01701 1046629.Ssal_01255 2.8e-277 960.7 Bacilli clcA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006821,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015672,GO:0015698,GO:0015706,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0031404,GO:0034220,GO:0042802,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 ko:K03281 ko00000 2.A.49 iAF1260.b0155,iB21_1397.B21_00153,iBWG_1329.BWG_0148,iE2348C_1286.E2348C_0162,iEC042_1314.EC042_0155,iEC55989_1330.EC55989_0149,iECBD_1354.ECBD_3463,iECDH10B_1368.ECDH10B_0135,iECDH1ME8569_1439.ECDH1ME8569_0149,iECD_1391.ECD_00154,iECIAI1_1343.ECIAI1_0153,iECO103_1326.ECO103_0155,iECSE_1348.ECSE_0156,iECUMN_1333.ECUMN_0152,iECW_1372.ECW_m0152,iEKO11_1354.EKO11_3761,iETEC_1333.ETEC_0151,iEcDH1_1363.EcDH1_3447,iEcE24377_1341.EcE24377A_0160,iEcolC_1368.EcolC_3504,iJO1366.b0155,iSSON_1240.SSON_0167,iUMNK88_1353.UMNK88_159,iWFL_1372.ECW_m0152,iY75_1357.Y75_RS00790,iZ_1308.Z0166 Bacteria 1TPX0@1239,4HD2H@91061,COG0038@1,COG0038@2 NA|NA|NA P Chloride transporter, ClC family BNPNBKBE_01702 264199.stu1181 1.2e-37 162.2 Bacteria pheA GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.3.1.12,2.3.1.79,4.2.1.51,5.4.99.5 ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715,R01728 RC00125,RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_2667 Bacteria COG1605@1,COG1605@2 NA|NA|NA E Chorismate mutase BNPNBKBE_01703 1046629.Ssal_01253 1.8e-207 728.4 Firmicutes XK27_05110 Bacteria 1TPX0@1239,COG0038@1,COG0038@2 NA|NA|NA P Chloride transporter ClC family BNPNBKBE_01704 1046629.Ssal_01252 1.1e-56 225.7 Bacilli rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6FT@1239,4HIK3@91061,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site BNPNBKBE_01707 1046629.Ssal_01245 3.2e-20 103.6 Bacilli WQ51_02665 Bacteria 1VPEZ@1239,2C91M@1,33E1E@2,4HRR2@91061 NA|NA|NA S Protein of unknown function (DUF3042) BNPNBKBE_01708 1046629.Ssal_01244 2.4e-159 568.2 Bacilli miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 1TPSC@1239,4HAVW@91061,COG0324@1,COG0324@2 NA|NA|NA J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) BNPNBKBE_01709 1046629.Ssal_01243 3.7e-85 320.9 Bacilli ytsP 1.8.4.14 ko:K08968 ko00270,map00270 R02025 RC00639 ko00000,ko00001,ko01000 Bacteria 1V6GQ@1239,4HH7X@91061,COG1956@1,COG1956@2 NA|NA|NA T GAF domain-containing protein BNPNBKBE_01710 1046629.Ssal_01242 1.3e-301 1041.6 Bacilli dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02341,ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPS9@1239,4HAUE@91061,COG2812@1,COG2812@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity BNPNBKBE_01711 1046629.Ssal_01240 5.3e-170 603.6 Bacilli birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 ko:K03524,ko:K04096 ko00780,ko01100,map00780,map01100 R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 Bacteria 1TQCU@1239,4HB60@91061,COG0340@1,COG0340@2,COG1654@1,COG1654@2 NA|NA|NA HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor BNPNBKBE_01712 1046629.Ssal_01239 3.3e-209 734.2 Bacilli metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCV@1239,4HB33@91061,COG0192@1,COG0192@2 NA|NA|NA H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme BNPNBKBE_01713 1046629.Ssal_00735 0.0 2155.9 Bacteria Bacteria COG5263@1,COG5263@2 NA|NA|NA S dextransucrase activity BNPNBKBE_01714 1046629.Ssal_00734 4.7e-88 332.8 Firmicutes Bacteria 1V0PX@1239,COG5263@1,COG5263@2 NA|NA|NA M Putative cell wall binding repeat BNPNBKBE_01715 1046629.Ssal_00732 0.0 1339.7 Bacteria Bacteria COG5263@1,COG5263@2 NA|NA|NA S dextransucrase activity BNPNBKBE_01716 1046629.Ssal_00731 7.3e-101 373.2 Bacilli pdxT GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 ko:K08681 ko00750,map00750 R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 iHN637.CLJU_RS19495 Bacteria 1V3I6@1239,4HFSZ@91061,COG0311@1,COG0311@2 NA|NA|NA H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS BNPNBKBE_01717 1046629.Ssal_00730 3.1e-156 557.8 Bacilli pdxS GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 ko:K06215 ko00750,map00750 R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 Bacteria 1TPSZ@1239,4H9RA@91061,COG0214@1,COG0214@2 NA|NA|NA H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively BNPNBKBE_01718 1046629.Ssal_00728 2.5e-299 1034.2 Bacteria Bacteria COG5263@1,COG5263@2 NA|NA|NA S dextransucrase activity BNPNBKBE_01719 1069533.Sinf_1920 1e-30 139.0 Firmicutes yegS GO:0001727,GO:0003674,GO:0003824,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0030258,GO:0044237,GO:0044238,GO:0044255,GO:0046834,GO:0071704 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 R02240 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TQ9A@1239,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase BNPNBKBE_01720 435842.HMPREF0848_00312 2.1e-123 448.4 Bacilli ybbA ko:K07017 ko00000 Bacteria 1V2YF@1239,4IQ46@91061,COG2819@1,COG2819@2 NA|NA|NA S Putative esterase BNPNBKBE_01721 435842.HMPREF0848_00311 7.7e-175 619.8 Bacilli fatB ko:K02016 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 1TSDG@1239,4HDG3@91061,COG0614@1,COG0614@2 NA|NA|NA P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component BNPNBKBE_01722 435842.HMPREF0848_00310 1.4e-133 482.3 Bacilli fecE 3.6.3.34 ko:K02013 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 Bacteria 1TP2Q@1239,4HETN@91061,COG1120@1,COG1120@2 NA|NA|NA HP ABC transporter BNPNBKBE_01723 435842.HMPREF0848_00309 3e-150 538.1 Bacilli fecD ko:K02015 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 1TPX6@1239,4HAUK@91061,COG0609@1,COG0609@2 NA|NA|NA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily BNPNBKBE_01724 435842.HMPREF0848_00308 3.7e-118 431.0 Bacteria Bacteria COG1266@1,COG1266@2 NA|NA|NA V CAAX protease self-immunity BNPNBKBE_01725 1046629.Ssal_01468 4.1e-150 537.3 Bacteria Bacteria 28KEH@1,2ZA0R@2 NA|NA|NA S Domain of unknown function (DUF4300) BNPNBKBE_01726 1046629.Ssal_01469 6.3e-91 340.1 Bacteria tetR Bacteria COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator BNPNBKBE_01727 1046629.Ssal_01470 3.4e-287 993.8 Bacilli norB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 ko:K08170,ko:K08218 ko01501,map01501 M00628,M00702 ko00000,ko00001,ko00002,ko01504,ko02000 2.A.1.25,2.A.1.3.23,2.A.1.3.59 Bacteria 1TPHW@1239,4H9YA@91061,COG0477@1,COG0477@2,COG2211@1,COG2211@2 NA|NA|NA P Major facilitator superfamily BNPNBKBE_01728 1123304.AQYA01000034_gene2108 7.1e-21 108.6 Bacilli Bacteria 1UJCN@1239,2DPDJ@1,331MW@2,4HP2C@91061 NA|NA|NA S Domain of unknown function (DUF4767) BNPNBKBE_01730 1046629.Ssal_01475 1.5e-107 395.6 Bacilli cutC GO:0006873,GO:0006875,GO:0006878,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0019725,GO:0030003,GO:0042221,GO:0042592,GO:0046688,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 ko:K06201 ko00000 Bacteria 1V3V5@1239,4HCVQ@91061,COG3142@1,COG3142@2 NA|NA|NA P Participates in the control of copper homeostasis BNPNBKBE_01731 888833.HMPREF9421_1585 4e-129 467.6 Firmicutes ko:K07052 ko00000 Bacteria 1V1I8@1239,COG1266@1,COG1266@2 NA|NA|NA S CAAX amino terminal protease family BNPNBKBE_01732 435842.HMPREF0848_00302 4.3e-98 364.0 Bacilli ypgQ ko:K06950 ko00000 Bacteria 1V7IZ@1239,4HIVB@91061,COG1418@1,COG1418@2 NA|NA|NA F HD superfamily hydrolase BNPNBKBE_01733 904306.HMPREF9192_1448 2e-95 355.1 Bacilli XK27_08140 Bacteria 1VGCX@1239,4HRBM@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family BNPNBKBE_01734 904306.HMPREF9192_1447 1.3e-148 532.3 Bacilli yitS Bacteria 1V229@1239,4IPK5@91061,COG1307@1,COG1307@2 NA|NA|NA S EDD domain protein, DegV family BNPNBKBE_01735 904306.HMPREF9192_1446 6.5e-202 709.9 Bacilli yeaN GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 ko:K03449 ko00000,ko02000 2.A.1.17 Bacteria 1TP9R@1239,4H9YZ@91061,COG2807@1,COG2807@2 NA|NA|NA P transporter BNPNBKBE_01736 322159.STER_0016 3.1e-74 284.6 Firmicutes ko:K07483 ko00000 Bacteria 1W68S@1239,COG2963@1,COG2963@2 NA|NA|NA L Transposase BNPNBKBE_01737 1316408.HSISM1_1539 7.1e-142 510.0 Bacilli ko:K07497 ko00000 Bacteria 1TQQY@1239,4HC8M@91061,COG2801@1,COG2801@2 NA|NA|NA L Transposase and inactivated derivatives BNPNBKBE_01738 435842.HMPREF0848_00298 1.7e-139 501.9 Bacilli Bacteria 1V0BE@1239,4HDZJ@91061,COG4221@1,COG4221@2 NA|NA|NA S Domain of unknown function (DUF4336) BNPNBKBE_01739 1316408.HSISM1_1087 2.8e-137 494.6 Bacilli Bacteria 1UMWY@1239,4HCGN@91061,COG0596@1,COG0596@2 NA|NA|NA S hydrolases or acyltransferases (alpha beta hydrolase superfamily) BNPNBKBE_01740 888048.HMPREF8577_0339 4.1e-89 334.0 Bacilli XK27_05370 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 Bacteria 1V436@1239,4HIUW@91061,COG0135@1,COG0135@2 NA|NA|NA E phosphoribosylanthranilate isomerase activity BNPNBKBE_01741 889204.HMPREF9423_0811 9.5e-130 469.5 Streptococcus infantis Bacteria 1V416@1239,43GEI@68892,4HRGM@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity BNPNBKBE_01742 888746.HMPREF9180_0748 3.3e-80 304.3 Bacilli 3.4.13.21,3.4.15.6 ko:K05995,ko:K13282 R09722 RC00064,RC00141 ko00000,ko01000,ko01002 Bacteria 1V9TG@1239,4HKAV@91061,COG4242@1,COG4242@2 NA|NA|NA E Belongs to the peptidase S51 family BNPNBKBE_01743 435842.HMPREF0848_00295 1.4e-77 295.4 Bacilli aacA7 GO:0003674,GO:0003824,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0034069,GO:0042221,GO:0046677,GO:0047663,GO:0050896 2.3.1.82 ko:K18816 br01600,ko00000,ko01000,ko01504 Bacteria 1VAQ8@1239,4HJJ6@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) family BNPNBKBE_01744 1054460.SPPN_01620 1.5e-36 158.3 Bacteria uvrX 2.7.7.7 ko:K02346,ko:K03502,ko:K14161 ko00000,ko01000,ko03400 Bacteria COG0389@1,COG0389@2 NA|NA|NA L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII BNPNBKBE_01745 562983.HMPREF0433_01099 5.9e-55 219.9 Bacilli Bacteria 1VW5E@1239,2DVQU@1,33WU0@2,4HWDN@91061 NA|NA|NA BNPNBKBE_01746 1054460.SPPN_01630 8.7e-60 236.1 Bacilli Bacteria 1VFMU@1239,2E59Z@1,33028@2,4HPP8@91061 NA|NA|NA BNPNBKBE_01747 1054460.SPPN_01635 1.1e-49 202.2 Bacilli Bacteria 1VFJD@1239,2E660@1,330UP@2,4HPUS@91061 NA|NA|NA BNPNBKBE_01748 1203590.HMPREF1481_00525 1e-257 895.6 Bacilli yheS_2 ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 3.A.1.121.1,3.A.1.121.3 Bacteria 1TQNA@1239,4H9VW@91061,COG0488@1,COG0488@2 NA|NA|NA S ATPase components of ABC transporters with duplicated ATPase domains BNPNBKBE_01749 1008453.HMPREF9957_0964 2e-217 761.5 Streptococcus mitis ko:K08217 br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 Bacteria 1UHRM@1239,2TQ4E@28037,4ISTP@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Transmembrane secretion effector BNPNBKBE_01750 1008453.HMPREF9957_0963 4.3e-22 109.8 Streptococcus mitis Bacteria 1U4XK@1239,29NGK@1,2TQDT@28037,309EI@2,4IENZ@91061 NA|NA|NA BNPNBKBE_01751 888746.HMPREF9180_0746 0.0 1317.8 Bacilli cadA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.3,3.6.3.5 ko:K01534 ko00000,ko01000 3.A.3.6 Bacteria 1TQ07@1239,4H9SP@91061,COG2217@1,COG2217@2 NA|NA|NA P COG2217 Cation transport ATPase BNPNBKBE_01752 435842.HMPREF0848_00285 1.6e-61 241.9 Bacilli smtB ko:K21903 ko00000,ko03000 Bacteria 1VA6G@1239,4HKYT@91061,COG0640@1,COG0640@2 NA|NA|NA K Transcriptional regulator BNPNBKBE_01753 435842.HMPREF0848_00284 2.4e-51 208.0 Bacilli zupT ko:K07238 ko00000,ko02000 2.A.5.5 Bacteria 1TP7J@1239,4HB3R@91061,COG0428@1,COG0428@2 NA|NA|NA P Mediates zinc uptake. May also transport other divalent cations BNPNBKBE_01754 435842.HMPREF0848_00283 1.9e-77 295.0 Bacilli ko:K07238 ko00000,ko02000 2.A.5.5 Bacteria 1TP7J@1239,4HB3R@91061,COG0428@1,COG0428@2 NA|NA|NA P Mediates zinc uptake. May also transport other divalent cations BNPNBKBE_01755 435842.HMPREF0848_00282 1.6e-252 878.2 Bacilli rumA GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 ko00000,ko01000,ko03009 Bacteria 1TP4H@1239,4HA6M@91061,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family BNPNBKBE_01756 1046629.Ssal_01496 2e-97 361.7 Bacteria mip Bacteria COG2128@1,COG2128@2 NA|NA|NA S hydroperoxide reductase activity BNPNBKBE_01757 322159.STER_0700 1.1e-200 705.7 Bacilli Bacteria 1UYHK@1239,4HCT5@91061,COG1960@1,COG1960@2 NA|NA|NA I acyl-CoA dehydrogenase BNPNBKBE_01758 1069533.Sinf_0933 4.5e-153 547.4 Bacteria ydiA ko:K03304,ko:K11041 ko05150,map05150 ko00000,ko00001,ko02000,ko02042 2.A.16,2.A.16.1 Bacteria COG1275@1,COG1275@2 NA|NA|NA P C4-dicarboxylate transporter malic acid transport protein BNPNBKBE_01759 904306.HMPREF9192_1382 2e-245 854.7 Bacilli msrR Bacteria 1TSWQ@1239,4HE66@91061,COG1316@1,COG1316@2 NA|NA|NA K Transcriptional regulator BNPNBKBE_01760 1046629.Ssal_01508 1.7e-151 542.0 Bacilli pheA GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51 ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024 R00691,R01373 RC00360 ko00000,ko00001,ko00002,ko01000 iYO844.BSU27900 Bacteria 1TPDN@1239,4HA96@91061,COG0077@1,COG0077@2 NA|NA|NA E Prephenate dehydratase BNPNBKBE_01761 904306.HMPREF9192_1380 1e-79 302.8 Bacilli aroK GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615 1.1.1.25,2.7.1.71,4.2.1.10,4.2.3.4 ko:K00014,ko:K00891,ko:K03785,ko:K03786,ko:K13829,ko:K15546 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R02413,R03083,R03084 RC00002,RC00078,RC00206,RC00847,RC00848 ko00000,ko00001,ko00002,ko01000,ko03000 iAPECO1_1312.APECO1_1620,iECOK1_1307.ECOK1_0367,iECS88_1305.ECS88_0383,iUMN146_1321.UM146_15425,iUTI89_1310.UTI89_C0407,iYL1228.KPN_00332 Bacteria 1VA6Z@1239,4HKD6@91061,COG0703@1,COG0703@2 NA|NA|NA F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate BNPNBKBE_01762 1046629.Ssal_01510 1.2e-233 815.5 Bacilli aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 1.3.1.12,1.3.1.43,2.5.1.19 ko:K00210,ko:K00220,ko:K00800 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00022,M00025,M00040 R00732,R01728,R03460 RC00125,RC00350 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0345 Bacteria 1TPIH@1239,4HBHZ@91061,COG0128@1,COG0128@2 NA|NA|NA E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate BNPNBKBE_01763 904306.HMPREF9192_1378 9.7e-172 609.4 Bacilli ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1UXY2@1239,4HD1S@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily BNPNBKBE_01764 1046629.Ssal_01512 4.2e-53 213.8 Bacilli yheA Bacteria 1VASS@1239,4HPJM@91061,COG3679@1,COG3679@2 NA|NA|NA S Belongs to the UPF0342 family BNPNBKBE_01765 1046629.Ssal_01513 2.7e-205 721.1 Bacilli tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 ko:K00210,ko:K00220,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025,M00040 R00732,R01728 RC00125 ko00000,ko00001,ko00002,ko01000 iYO844.BSU22610 Bacteria 1TPXG@1239,4HBI4@91061,COG0287@1,COG0287@2 NA|NA|NA E prephenate dehydrogenase BNPNBKBE_01766 904306.HMPREF9192_1375 1.9e-217 761.5 Bacilli aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0976,iNJ661.Rv2540c Bacteria 1TQ40@1239,4HA0H@91061,COG0082@1,COG0082@2 NA|NA|NA E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system BNPNBKBE_01767 1046629.Ssal_01515 5.9e-202 709.9 Bacilli aroB 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPKZ@1239,4HAKN@91061,COG0337@1,COG0337@2 NA|NA|NA E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) BNPNBKBE_01768 904306.HMPREF9192_1373 2.2e-159 568.2 Bacilli aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQRY@1239,4HD4R@91061,COG0169@1,COG0169@2 NA|NA|NA E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) BNPNBKBE_01769 904306.HMPREF9192_1372 4.4e-118 430.6 Bacilli aroD GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25,4.2.1.10 ko:K03785,ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413,R03084 RC00206,RC00848 ko00000,ko00001,ko00002,ko01000 Bacteria 1VHVX@1239,4IPJP@91061,COG0710@1,COG0710@2 NA|NA|NA E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate BNPNBKBE_01770 1046629.Ssal_01518 1.8e-215 755.0 Bacilli ywbD 2.1.1.191 ko:K06969 ko00000,ko01000,ko03009 Bacteria 1TRAJ@1239,4HAA1@91061,COG1092@1,COG1092@2 NA|NA|NA J Methyltransferase BNPNBKBE_01771 1046629.Ssal_01519 0.0 1293.5 Bacilli ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 R05081,R10849 RC00017 ko00000,ko00001,ko01000 Bacteria 1TRMA@1239,4H9S0@91061,COG1368@1,COG1368@2 NA|NA|NA M Belongs to the LTA synthase family BNPNBKBE_01772 1046629.Ssal_01520 4.6e-25 119.8 Firmicutes WQ51_00785 Bacteria 1W67C@1239,2FKS5@1,34CCP@2 NA|NA|NA BNPNBKBE_01773 1046629.Ssal_01521 7.4e-247 859.4 Bacilli eno GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0009986,GO:0016829,GO:0016835,GO:0016836,GO:0019899,GO:0030312,GO:0035375,GO:0043236,GO:0044424,GO:0044464,GO:0044877,GO:0050840,GO:0071944 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 1TP2S@1239,4HAKI@91061,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis BNPNBKBE_01774 1046629.Ssal_01522 8.7e-78 296.2 Bacilli yueI Bacteria 1VFCV@1239,4HNNE@91061,COG5506@1,COG5506@2 NA|NA|NA S Protein of unknown function (DUF1694) BNPNBKBE_01775 1046629.Ssal_01524 2.8e-194 684.5 Firmicutes glxK 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 R08572 RC00002,RC00428 ko00000,ko00001,ko01000 Bacteria 1TPSI@1239,COG1929@1,COG1929@2 NA|NA|NA G Belongs to the glycerate kinase type-1 family BNPNBKBE_01776 1046629.Ssal_01525 3e-190 671.0 Bacilli yyaQ Bacteria 1V4K7@1239,4HP2K@91061,COG2315@1,COG2315@2 NA|NA|NA S YjbR BNPNBKBE_01777 1046629.Ssal_01526 1.9e-181 641.7 Bacilli ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02529 ko00000,ko03000 Bacteria 1TQ7K@1239,4H9NG@91061,COG1609@1,COG1609@2 NA|NA|NA K Catabolite control protein A BNPNBKBE_01778 1046629.Ssal_01528 2.4e-195 688.0 Bacilli pepQ 3.4.13.9 ko:K01271 ko00000,ko01000,ko01002 Bacteria 1TQ6R@1239,4HA5I@91061,COG0006@1,COG0006@2 NA|NA|NA E Belongs to the peptidase M24B family BNPNBKBE_01779 1046629.Ssal_01529 8.4e-63 246.1 Bacilli yugI 5.3.1.9 ko:K01810,ko:K02945,ko:K07570,ko:K07571,ko:K19142 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko03010,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map03010 M00001,M00004,M00114,M00178 R02739,R02740,R03321 RC00376,RC00563 br01610,ko00000,ko00001,ko00002,ko01000,ko02048,ko03011,ko04147 Bacteria 1VASQ@1239,4HKSW@91061,COG1098@1,COG1098@2 NA|NA|NA J RNA binding protein, contains ribosomal protein S1 domain BNPNBKBE_01780 904306.HMPREF9192_1357 1.5e-274 951.4 Bacilli ppiB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03768 ko00000,ko01000,ko03110 Bacteria 1TRHW@1239,4H9V0@91061,COG0561@1,COG0561@2,COG0652@1,COG0652@2 NA|NA|NA G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides BNPNBKBE_01781 1046629.Ssal_01531 6.6e-81 306.6 Bacilli smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 ko:K03664 ko00000 Bacteria 1V3IJ@1239,4HGZX@91061,COG0691@1,COG0691@2 NA|NA|NA O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA BNPNBKBE_01782 1046629.Ssal_01532 0.0 1466.4 Bacilli rnr ko:K12573,ko:K12585 ko03018,map03018 M00391 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 1TQ1G@1239,4HBBH@91061,COG0557@1,COG0557@2 NA|NA|NA J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs BNPNBKBE_01783 904306.HMPREF9192_1354 2e-33 147.9 Bacilli secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VEQR@1239,4HNKC@91061,COG1314@1,COG1314@2 NA|NA|NA U Preprotein translocase subunit SecG BNPNBKBE_01784 1046629.Ssal_01534 1e-221 775.8 Bacilli mdtG GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085 ko:K08161 ko00000,ko02000 2.A.1.2.20 Bacteria 1TRDJ@1239,4H9Q9@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily BNPNBKBE_01785 1046629.Ssal_01535 1.5e-93 349.0 Bacilli coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24,3.2.2.23,4.2.99.18 ko:K00859,ko:K08309,ko:K10563 ko00770,ko01100,ko03410,map00770,map01100,map03410 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01011,ko03400 GH23 iIT341.HP0831 Bacteria 1V6FS@1239,4HII3@91061,COG0237@1,COG0237@2 NA|NA|NA H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A BNPNBKBE_01786 1046629.Ssal_01536 3.9e-145 520.8 Bacilli fpg 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPM9@1239,4H9Q7@91061,COG0266@1,COG0266@2 NA|NA|NA L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates BNPNBKBE_01787 1046629.Ssal_01539 3.4e-166 590.9 Bacilli era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 ko:K03595,ko:K06883 ko00000,ko03009,ko03029 Bacteria 1TP3R@1239,4H9WF@91061,COG1159@1,COG1159@2 NA|NA|NA M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism BNPNBKBE_01788 1046629.Ssal_01540 6.4e-64 250.0 Bacilli dgkA 2.7.1.107,2.7.1.66 ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 R02240,R05626 RC00002,RC00017 ko00000,ko00001,ko01000 iAF987.Gmet_2369,iSB619.SA_RS07900 Bacteria 1VEGR@1239,4HNKN@91061,COG0818@1,COG0818@2 NA|NA|NA M Diacylglycerol kinase BNPNBKBE_01789 1046629.Ssal_01541 1.3e-87 328.9 Bacilli ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 1V6BU@1239,4HIIE@91061,COG0319@1,COG0319@2 NA|NA|NA S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA BNPNBKBE_01790 1046629.Ssal_01542 6.8e-145 520.0 Bacilli licT ko:K02538,ko:K03488 ko00000,ko03000 Bacteria 1TT5A@1239,4HC5Y@91061,COG3711@1,COG3711@2 NA|NA|NA K antiterminator BNPNBKBE_01791 1046629.Ssal_01543 1.3e-105 389.0 Bacilli recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1TR87@1239,4HAZR@91061,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO BNPNBKBE_01792 1046629.Ssal_01544 0.0 1225.7 Bacilli pbp2b 3.4.16.4 ko:K00687,ko:K05515,ko:K12553,ko:K21465 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Bacteria 1TQHY@1239,4HAFX@91061,COG0768@1,COG0768@2 NA|NA|NA M penicillin-binding protein BNPNBKBE_01793 1046629.Ssal_01545 1.4e-142 512.3 Bacilli nnrD 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 1TNZE@1239,4HBZC@91061,COG0063@1,COG0063@2 NA|NA|NA H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration BNPNBKBE_01794 904306.HMPREF9192_1342 2.4e-153 548.1 Bacilli folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1P@1239,4H9Q6@91061,COG0190@1,COG0190@2 NA|NA|NA F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate BNPNBKBE_01795 1046629.Ssal_01547 6.1e-148 530.0 Bacilli Bacteria 1V37Y@1239,4ITDD@91061,COG2267@1,COG2267@2 NA|NA|NA I Alpha/beta hydrolase family BNPNBKBE_01796 759913.SDSE_1600 6.6e-08 62.4 Streptococcus dysgalactiae group Bacteria 1MA5P@119603,1TXF8@1239,2DJ8A@1,304YV@2,4I6DK@91061 NA|NA|NA BNPNBKBE_01797 1046629.Ssal_01549 0.0 1343.9 Bacilli feoB ko:K04759 ko00000,ko02000 9.A.8.1 Bacteria 1TP7E@1239,4HBCS@91061,COG0370@1,COG0370@2 NA|NA|NA P transporter of a GTP-driven Fe(2 ) uptake system BNPNBKBE_01798 904306.HMPREF9192_1338 1.7e-76 292.0 Bacilli feoA ko:K04758 ko00000,ko02000 Bacteria 1VEHC@1239,4HPFS@91061,COG1918@1,COG1918@2 NA|NA|NA P FeoA domain protein BNPNBKBE_01799 1046629.Ssal_01552 7.1e-130 469.9 Bacilli glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E abc transporter atp-binding protein BNPNBKBE_01800 1046629.Ssal_01553 5.8e-118 430.3 Bacilli WQ51_01820 ko:K02029,ko:K02030,ko:K10040,ko:K17073,ko:K17074 ko02010,map02010 M00228,M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1TPM3@1239,4IQKK@91061,COG0765@1,COG0765@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component BNPNBKBE_01801 1046629.Ssal_01554 1e-34 152.1 Bacilli ykuJ Bacteria 1VKD0@1239,4HRGC@91061,COG4703@1,COG4703@2 NA|NA|NA S protein conserved in bacteria BNPNBKBE_01802 1046629.Ssal_01556 1.8e-181 641.7 Bacilli argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPF2@1239,4H9X8@91061,COG0078@1,COG0078@2 NA|NA|NA E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline BNPNBKBE_01803 904306.HMPREF9192_1333 0.0 1297.7 Bacilli clpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03697 ko00000,ko03110 Bacteria 1TPMU@1239,4HA0V@91061,COG0542@1,COG0542@2 NA|NA|NA O Belongs to the ClpA ClpB family BNPNBKBE_01804 1046629.Ssal_01558 6.3e-84 316.6 Bacilli mutT 3.5.4.33,3.6.1.13,3.6.1.55 ko:K01515,ko:K03574,ko:K11991 ko00230,map00230 R01054,R10223 RC00002,RC00477 ko00000,ko00001,ko01000,ko03016,ko03400 Bacteria 1VH6Q@1239,4HQVJ@91061,COG0494@1,COG0494@2 NA|NA|NA L Belongs to the Nudix hydrolase family BNPNBKBE_01805 1046629.Ssal_01559 6.2e-48 196.4 Bacilli XK27_09445 Bacteria 1VFRS@1239,2EBZ8@1,335YI@2,4HNUK@91061 NA|NA|NA S Domain of unknown function (DUF1827) BNPNBKBE_01806 1046629.Ssal_01560 1.2e-172 612.5 Bacilli ko:K22230 ko00562,ko01120,map00562,map01120 R09954 RC00182 ko00000,ko00001,ko01000 Bacteria 1TQSS@1239,4HDXF@91061,COG0673@1,COG0673@2 NA|NA|NA S oxidoreductase BNPNBKBE_01807 435842.HMPREF0848_00231 9.5e-228 795.8 Bacilli murN 2.3.2.16 ko:K11693,ko:K12554 ko00550,ko01100,map00550,map01100 R08776,R08780 RC00055,RC00064,RC00096 ko00000,ko00001,ko01000,ko01011 Bacteria 1V181@1239,4HEVU@91061,COG2348@1,COG2348@2 NA|NA|NA V FemAB family BNPNBKBE_01808 1046629.Ssal_01562 2.4e-116 424.9 Bacteria Bacteria COG0398@1,COG0398@2 NA|NA|NA M Pfam SNARE associated Golgi protein BNPNBKBE_01809 1046629.Ssal_01563 3.2e-107 394.4 Bacilli Bacteria 1VGN9@1239,2DMIQ@1,32RV1@2,4I0DZ@91061 NA|NA|NA S Domain of Unknown Function with PDB structure (DUF3862) BNPNBKBE_01812 1046629.Ssal_01564 2.5e-204 718.0 Bacilli rpsA 1.17.7.4 ko:K02945,ko:K03527 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 Bacteria 1TQ9N@1239,4H9PX@91061,COG0539@1,COG0539@2 NA|NA|NA J ribosomal protein S1 BNPNBKBE_01815 1035187.HMPREF9959_0525 3.3e-17 94.0 Streptococcus mitis Bacteria 1U4J6@1239,29N96@1,2TPZ6@28037,30971@2,4IEAX@91061 NA|NA|NA S Protein of unknown function (DUF2969) BNPNBKBE_01816 1046629.Ssal_01567 4.5e-199 700.3 Bacilli ilvE 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TQQI@1239,4HASX@91061,COG0115@1,COG0115@2 NA|NA|NA E Aminotransferase BNPNBKBE_01817 904306.HMPREF9192_1319 0.0 1565.8 Bacilli parC GO:0005575,GO:0005622,GO:0005623,GO:0009330,GO:0032991,GO:0044424,GO:0044464 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TRE7@1239,4HAQB@91061,COG0188@1,COG0188@2 NA|NA|NA L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule BNPNBKBE_01818 889204.HMPREF9423_1044 7.4e-12 77.4 Streptococcus infantis Bacteria 1UQEG@1239,2BAK8@1,32411@2,43FF9@68892,4I578@91061 NA|NA|NA BNPNBKBE_01820 1046629.Ssal_01572 0.0 1223.0 Bacilli parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470,ko:K02622 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TQCF@1239,4H9UC@91061,COG0187@1,COG0187@2 NA|NA|NA L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule BNPNBKBE_01821 1046629.Ssal_01573 1.1e-107 396.0 Bacilli plsY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15,3.5.1.104 ko:K08591,ko:K22278 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1VA3J@1239,4HC55@91061,COG0344@1,COG0344@2 NA|NA|NA I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP BNPNBKBE_01822 759913.SDSE_1678 6.1e-13 80.5 Streptococcus dysgalactiae group Bacteria 1M9TG@119603,1TXCP@1239,2DJ7H@1,304X7@2,4I6AH@91061 NA|NA|NA L Helix-hairpin-helix DNA-binding motif class 1 BNPNBKBE_01823 1035184.HMPREF1042_0385 2.2e-30 137.9 Streptococcus anginosus group Bacteria 1VYRT@1239,2BXCI@1,346RD@2,42DR8@671232,4HYPP@91061 NA|NA|NA S Domain of unknown function (DUF1912) BNPNBKBE_01824 1046629.Ssal_01576 1.3e-171 609.0 Bacilli mmuM GO:0003674,GO:0003824,GO:0005488,GO:0006575,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008270,GO:0008757,GO:0008898,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033477,GO:0033554,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:1901564 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHQ5@1239,4HAS6@91061,COG2040@1,COG2040@2 NA|NA|NA H Homocysteine BNPNBKBE_01825 1046629.Ssal_01577 8.3e-249 865.9 Firmicutes mmuP GO:0000096,GO:0000097,GO:0000100,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0015806,GO:0016020,GO:0016053,GO:0019752,GO:0022857,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682 ko:K02205,ko:K03293,ko:K16235,ko:K16236 ko00000,ko02000 2.A.3.1,2.A.3.1.10 Bacteria 1UHNR@1239,COG0833@1,COG0833@2 NA|NA|NA E amino acid BNPNBKBE_01826 1046629.Ssal_01578 3.9e-110 404.1 Bacilli engB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03978 ko00000,ko03036 Bacteria 1TSPW@1239,4HBXZ@91061,COG0218@1,COG0218@2 NA|NA|NA D Necessary for normal cell division and for the maintenance of normal septation BNPNBKBE_01827 1046629.Ssal_01579 2.6e-225 787.7 Bacilli clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 1TQ00@1239,4H9U4@91061,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP BNPNBKBE_01828 435842.HMPREF0848_00215 9.7e-22 108.6 Bacilli Bacteria 1W5G0@1239,2DFKW@1,2ZS8U@2,4HZFD@91061 NA|NA|NA BNPNBKBE_01829 904306.HMPREF9192_1309 1.2e-88 332.4 Bacilli folA 1.5.1.3,1.5.1.47,2.1.1.45,3.5.4.12 ko:K00287,ko:K00560,ko:K01493,ko:K05896,ko:K17364 ko00240,ko00670,ko00790,ko01100,ko01523,map00240,map00670,map00790,map01100,map01523 M00053,M00126,M00429,M00840 R00936,R00937,R00939,R00940,R01663,R02101,R02235,R02236,R03388,R11765 RC00074,RC00109,RC00110,RC00158,RC00219,RC00332,RC01584 ko00000,ko00001,ko00002,ko01000,ko02044,ko03036 Bacteria 1VB80@1239,4HIGJ@91061,COG0262@1,COG0262@2 NA|NA|NA H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis BNPNBKBE_01830 1046629.Ssal_01582 2.7e-165 587.8 Bacilli thyA 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSIR@1239,4HI1C@91061,COG0207@1,COG0207@2 NA|NA|NA F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis BNPNBKBE_01831 1046629.Ssal_01584 1.6e-208 731.9 Bacilli mvaS 2.3.3.10 ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR4K@1239,4HA67@91061,COG3425@1,COG3425@2 NA|NA|NA I synthase BNPNBKBE_01832 904306.HMPREF9192_1306 4.5e-225 786.9 Bacilli mvaA 1.1.1.34,1.1.1.88,2.3.1.9 ko:K00021,ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,ko04152,ko04976,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020,map04152,map04976 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081,R02082 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TPNY@1239,4HBQ3@91061,COG1257@1,COG1257@2 NA|NA|NA C Belongs to the HMG-CoA reductase family BNPNBKBE_01833 1046629.Ssal_01586 3e-78 297.7 Firmicutes ko:K11068 ko00000,ko02042 Bacteria 1V7Z4@1239,COG0789@1,COG0789@2 NA|NA|NA K hmm pf08876 BNPNBKBE_01834 435842.HMPREF0848_00209 1.2e-118 432.6 Bacilli yqfA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K11068 ko00000,ko02042 Bacteria 1TTA5@1239,4HDYT@91061,COG1272@1,COG1272@2 NA|NA|NA K protein, Hemolysin III BNPNBKBE_01835 1046629.Ssal_01589 4.1e-29 133.3 Bacilli pspC Bacteria 1VKBQ@1239,4HRGW@91061,COG1983@1,COG1983@2 NA|NA|NA KT PspC domain protein BNPNBKBE_01836 1046629.Ssal_01590 4.2e-192 677.2 Bacilli Bacteria 1VFZ3@1239,2DQ82@1,3357U@2,4HNXV@91061 NA|NA|NA S Protein of unknown function (DUF3114) BNPNBKBE_01837 1046629.Ssal_01591 2.1e-158 565.1 Bacilli Bacteria 1V202@1239,4HJ0U@91061,COG0596@1,COG0596@2 NA|NA|NA S hydrolases or acyltransferases (alpha beta hydrolase superfamily) BNPNBKBE_01838 1046629.Ssal_01592 0.0 1283.1 Bacilli thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP78@1239,4HABZ@91061,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) BNPNBKBE_01840 1046629.Ssal_01594 5.7e-247 859.8 Bacilli mgs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 GT4 Bacteria 1TPTA@1239,4HA41@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase, group 1 family protein BNPNBKBE_01841 1046629.Ssal_01595 5.2e-192 676.8 Bacilli dgs 2.4.1.208 ko:K13677 ko00561,ko01100,map00561,map01100 R05164 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003 GT4 Bacteria 1TPSS@1239,4HBKA@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase, group 1 family protein BNPNBKBE_01842 1046629.Ssal_01596 0.0 1466.8 Bacteria ko:K02460 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria COG3156@1,COG3156@2,COG4932@1,COG4932@2 NA|NA|NA U protein secretion BNPNBKBE_01843 1046629.Ssal_01597 7.7e-118 429.9 Bacilli mtnN 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 Bacteria 1U7WK@1239,4HB8K@91061,COG0775@1,COG0775@2 NA|NA|NA E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively BNPNBKBE_01844 1046629.Ssal_01598 1.5e-21 108.6 Bacilli Bacteria 1W5SW@1239,2DC3Q@1,2ZCSA@2,4I23E@91061 NA|NA|NA BNPNBKBE_01845 904306.HMPREF9192_1293 1.2e-94 352.4 Bacilli nudF 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 iHN637.CLJU_RS05505,iSB619.SA_RS07540,iYO844.BSU23610 Bacteria 1V6F5@1239,4HII9@91061,COG0494@1,COG0494@2 NA|NA|NA L AdP-ribose pyrophosphatase BNPNBKBE_01846 1046629.Ssal_01601 9.3e-240 835.9 Bacilli glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042,ko:K11528 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP88@1239,4H9V5@91061,COG1207@1,COG1207@2 NA|NA|NA M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain BNPNBKBE_01847 1046629.Ssal_01602 0.0 1669.1 Bacilli mgtA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132 3.6.3.2 ko:K01531 ko00000,ko01000 3.A.3.4 iSF_1195.SF4248 Bacteria 1TPF5@1239,4HBQJ@91061,COG0474@1,COG0474@2 NA|NA|NA P COG0474 Cation transport ATPase BNPNBKBE_01848 1046629.Ssal_01605 3.6e-185 654.1 Bacilli fni 1.1.1.88,5.3.3.2 ko:K00054,ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123,R02081 RC00004,RC00455,RC00644 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQZ3@1239,4HAMV@91061,COG1304@1,COG1304@2 NA|NA|NA C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) BNPNBKBE_01849 1046629.Ssal_01606 4.9e-166 590.5 Bacilli mvaK2 2.7.1.36,2.7.1.43,2.7.4.2 ko:K00869,ko:K00938,ko:K16190 ko00040,ko00053,ko00520,ko00900,ko01100,ko01110,ko01130,ko04146,map00040,map00053,map00520,map00900,map01100,map01110,map01130,map04146 M00014,M00095 R01476,R02245,R03245 RC00002,RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPKP@1239,4HWXG@91061,COG1577@1,COG1577@2 NA|NA|NA I phosphomevalonate kinase BNPNBKBE_01850 904306.HMPREF9192_1286 1e-168 599.4 Bacilli mvaD 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQXR@1239,4HAM6@91061,COG3407@1,COG3407@2 NA|NA|NA I diphosphomevalonate decarboxylase BNPNBKBE_01851 264199.stu0559 1e-135 489.6 Bacilli mvk 1.1.1.88,2.3.3.10,2.7.1.36 ko:K00054,ko:K00869,ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,ko04146,map00072,map00280,map00650,map00900,map01100,map01110,map01130,map04146 M00088,M00095 R01978,R02081,R02245 RC00002,RC00004,RC00017,RC00503,RC00644 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPVW@1239,4IRCB@91061,COG1577@1,COG1577@2 NA|NA|NA I mevalonate kinase BNPNBKBE_01852 904306.HMPREF9192_1283 7.5e-247 859.4 Bacilli merA GO:0000302,GO:0000305,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0019725,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901530,GO:1901700,GO:1990748 1.16.1.1 ko:K00520,ko:K21739 ko00000,ko01000 Bacteria 1TP1W@1239,4HBZF@91061,COG1249@1,COG1249@2 NA|NA|NA C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family BNPNBKBE_01853 999425.HMPREF9186_01871 3e-179 634.8 Bacilli ybdK Bacteria 1UIWF@1239,4HJWW@91061,COG0642@1,COG0642@2,COG2770@1,COG2770@2 NA|NA|NA T ATPase histidine kinase DNA gyrase B HSP90 domain protein BNPNBKBE_01854 888048.HMPREF8577_0127 1.3e-109 402.5 Bacilli Bacteria 1TS81@1239,4HG2C@91061,COG0745@1,COG0745@2 NA|NA|NA T Response regulator receiver domain protein BNPNBKBE_01855 888833.HMPREF9421_1849 5.5e-50 204.1 Bacteria Bacteria COG3212@1,COG3212@2 NA|NA|NA T peptidase BNPNBKBE_01856 435842.HMPREF0848_00187 5.6e-120 437.2 Firmicutes ko:K16264 ko00000,ko02000 2.A.4.1 Bacteria 1UJ13@1239,COG2021@1,COG2021@2 NA|NA|NA E alpha/beta hydrolase fold BNPNBKBE_01858 1046629.Ssal_01614 6.6e-196 689.9 Bacilli ald GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009653,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030435,GO:0032502,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 R00396 RC00008 ko00000,ko00001,ko01000 iAF987.Gmet_1099 Bacteria 1TNZ5@1239,4HABX@91061,COG0686@1,COG0686@2 NA|NA|NA C Belongs to the AlaDH PNT family BNPNBKBE_01859 1046629.Ssal_01616 6.5e-215 753.1 Bacilli hipO 3.5.1.47 ko:K01436,ko:K05823,ko:K21613 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPD7@1239,4H9WQ@91061,COG1473@1,COG1473@2 NA|NA|NA E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase BNPNBKBE_01860 264199.stu0553 2.7e-126 458.0 Bacilli rsuA 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 ko00000,ko01000,ko03009 Bacteria 1TQZ2@1239,4H9VU@91061,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family BNPNBKBE_01861 1046629.Ssal_01618 3.9e-114 417.5 Bacilli Bacteria 1V6KW@1239,4IPIC@91061,COG1814@1,COG1814@2 NA|NA|NA S VIT family BNPNBKBE_01862 706437.HMPREF0813_01845 9.2e-25 120.2 Streptococcus anginosus group Bacteria 1TVS7@1239,29ZMX@1,30MNF@2,42DTT@671232,4I418@91061 NA|NA|NA BNPNBKBE_01863 1046629.Ssal_01621 1e-27 128.6 Bacilli XK27_00085 ko:K07729 ko00000,ko03000 Bacteria 1VERT@1239,4HNID@91061,COG1476@1,COG1476@2 NA|NA|NA K Transcriptional BNPNBKBE_01864 1046629.Ssal_01622 9e-197 692.6 Bacilli yceA ko:K07146 ko00000 Bacteria 1TRG7@1239,4HA0J@91061,COG1054@1,COG1054@2 NA|NA|NA S Belongs to the UPF0176 family BNPNBKBE_01865 1046629.Ssal_01624 4.7e-123 447.2 Bacilli nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0008150,GO:0008152,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135 3.1.1.31,3.5.99.6 ko:K01057,ko:K02564 ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R00765,R02035 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP10@1239,4HAG4@91061,COG0363@1,COG0363@2 NA|NA|NA G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion BNPNBKBE_01866 1046629.Ssal_01625 2.1e-199 701.4 Bacilli queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 ko00000,ko01000,ko03016 Bacteria 1TPKD@1239,4H9PT@91061,COG0809@1,COG0809@2 NA|NA|NA J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) BNPNBKBE_01867 1046629.Ssal_01626 3.7e-154 550.8 Bacilli lmrA ko:K06147,ko:K18888 ko02010,map02010 M00706 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_01868 1046629.Ssal_01626 1.1e-66 259.2 Bacilli lmrA ko:K06147,ko:K18888 ko02010,map02010 M00706 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_01869 1046629.Ssal_01626 1.1e-73 282.7 Bacilli lmrA ko:K06147,ko:K18888 ko02010,map02010 M00706 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_01870 435842.HMPREF0848_00173 0.0 1097.8 Bacilli mdlB ko:K06147,ko:K18887 ko02010,map02010 M00706 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,4H9SC@91061,COG1132@1,COG1132@2 NA|NA|NA V abc transporter atp-binding protein BNPNBKBE_01871 1449343.JQLQ01000002_gene667 1.2e-100 373.2 Carnobacteriaceae int Bacteria 1TTJI@1239,27FYE@186828,4HDG6@91061,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase, N-terminal SAM-like domain BNPNBKBE_01872 1235800.C819_03205 1.5e-64 253.4 Clostridia Bacteria 1VHC8@1239,24PSV@186801,COG1479@1,COG1479@2 NA|NA|NA S Protein of unknown function DUF262 BNPNBKBE_01873 1235800.C819_03206 1.1e-59 237.3 Clostridia Bacteria 1VIJC@1239,251VZ@186801,2ATE6@1,31IXJ@2 NA|NA|NA BNPNBKBE_01874 1507.HMPREF0262_00924 3.3e-63 247.7 Clostridiaceae vsr ko:K07458 ko00000,ko01000,ko03400 Bacteria 1VA1Q@1239,25AZ7@186801,36SFK@31979,COG3727@1,COG3727@2 NA|NA|NA L May nick specific sequences that contain T G mispairs resulting from m5C-deamination BNPNBKBE_01875 742738.HMPREF9460_03939 1.4e-156 558.9 Clostridia resC Bacteria 1V53U@1239,24BRD@186801,28J7V@1,2Z936@2 NA|NA|NA L NgoMIV restriction enzyme BNPNBKBE_01876 742738.HMPREF9460_03938 1.4e-186 658.7 unclassified Clostridiales dcm 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Bacteria 1TSNX@1239,2490C@186801,269DA@186813,COG0270@1,COG0270@2 NA|NA|NA H Psort location Cytoplasmic, score 8.96 BNPNBKBE_01877 1507.HMPREF0262_00927 3.5e-26 123.6 Clostridiaceae 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Bacteria 1VEM0@1239,24QPN@186801,36MSY@31979,COG3655@1,COG3655@2 NA|NA|NA K Psort location Cytoplasmic, score BNPNBKBE_01878 742738.HMPREF9460_03937 3.4e-36 157.1 unclassified Clostridiales Bacteria 1VB18@1239,24MZP@186801,269KN@186813,2CZEX@1,32T68@2 NA|NA|NA BNPNBKBE_01879 742738.HMPREF9460_03936 5.8e-183 646.7 unclassified Clostridiales 3.6.4.12 ko:K17680 ko00000,ko01000,ko03029 Bacteria 1TU5N@1239,247KK@186801,267IW@186813,COG3598@1,COG3598@2 NA|NA|NA L AAA domain BNPNBKBE_01880 742738.HMPREF9460_03935 7.2e-53 213.0 unclassified Clostridiales Bacteria 1V6TG@1239,24JD1@186801,2697K@186813,2AQJ5@1,31FRY@2 NA|NA|NA S Psort location Cytoplasmic, score BNPNBKBE_01881 742738.HMPREF9460_03934 7e-203 713.0 unclassified Clostridiales Bacteria 1TTJI@1239,247V6@186801,2689P@186813,COG0582@1,COG0582@2 NA|NA|NA L Site-specific recombinase, phage integrase family BNPNBKBE_01882 742738.HMPREF9460_03933 3e-27 127.1 unclassified Clostridiales Bacteria 1VH5Y@1239,24S88@186801,26CQR@186813,2E5UB@1,331IU@2 NA|NA|NA S Mga helix-turn-helix domain BNPNBKBE_01883 742738.HMPREF9460_03932 1.1e-81 309.3 unclassified Clostridiales Bacteria 1V1JY@1239,24HXG@186801,268RE@186813,COG1396@1,COG1396@2 NA|NA|NA K Psort location Cytoplasmic, score BNPNBKBE_01884 469617.FUAG_01809 1.7e-119 435.6 Bacteria 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria COG0322@1,COG0322@2 NA|NA|NA L excinuclease ABC activity BNPNBKBE_01885 397290.C810_01569 1.4e-52 212.2 unclassified Lachnospiraceae Bacteria 1VCA6@1239,24P0P@186801,27NX6@186928,COG1598@1,COG1598@2 NA|NA|NA S HicB_like antitoxin of bacterial toxin-antitoxin system BNPNBKBE_01886 592031.GCWU000322_00749 1.2e-19 101.7 Clostridia Bacteria 1VM1Z@1239,25EER@186801,2DRZV@1,33DVH@2 NA|NA|NA S HicA toxin of bacterial toxin-antitoxin, BNPNBKBE_01887 1203606.HMPREF1526_02025 4.2e-17 93.2 Clostridiaceae 3.5.1.28 ko:K11066,ko:K12287 ko00000,ko01000,ko01011,ko02044 Bacteria 1V43P@1239,25EEF@186801,36W95@31979,COG3023@1,COG3023@2,COG5632@1,COG5632@2 NA|NA|NA M Ami_2 BNPNBKBE_01891 435842.HMPREF0848_01017 0.0 1156.4 Bacteria sraP ko:K18491,ko:K21449 ko04550,map04550 ko00000,ko00001,ko02000,ko03000 1.B.40.2 Bacteria COG5295@1,COG5295@2 NA|NA|NA UW Hep Hag repeat protein BNPNBKBE_01892 1046629.Ssal_01403 9e-34 151.0 Firmicutes 2.4.1.21 ko:K00703,ko:K01990,ko:K02519,ko:K11904 ko00500,ko01100,ko01110,ko02026,ko03070,map00500,map01100,map01110,map02026,map03070 M00254,M00334,M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003,ko02000,ko02044,ko03012,ko03029 3.A.1,3.A.23.1 GT5 Bacteria 1W0JP@1239,COG5373@1,COG5373@2,COG5434@1,COG5434@2 NA|NA|NA M Right handed beta helix region BNPNBKBE_01893 1046629.Ssal_01401 5.3e-176 623.6 Bacilli spd ko:K15051 ko00000 Bacteria 1TR37@1239,4HK9Z@91061,COG2169@1,COG2169@2 NA|NA|NA F DNA RNA non-specific endonuclease BNPNBKBE_01894 904306.HMPREF9192_1175 7.7e-92 343.2 Bacilli lemA ko:K03744 ko00000 Bacteria 1V1G7@1239,4IR1J@91061,COG1704@1,COG1704@2 NA|NA|NA S LemA family BNPNBKBE_01895 1046629.Ssal_01399 1.3e-133 482.6 Bacilli htpX ko:K03799 M00743 ko00000,ko00002,ko01000,ko01002 Bacteria 1TP23@1239,4HB11@91061,COG0501@1,COG0501@2 NA|NA|NA O Belongs to the peptidase M48B family BNPNBKBE_01896 1046629.Ssal_01398 6.1e-117 426.8 Bacilli sirR ko:K03709 ko00000,ko03000 Bacteria 1V4V7@1239,4HHV4@91061,COG1321@1,COG1321@2 NA|NA|NA K iron dependent repressor BNPNBKBE_01897 1046629.Ssal_01397 3.6e-171 607.4 Bacilli sitA GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0042597,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K09818,ko:K11601,ko:K11604,ko:K11704,ko:K19971,ko:K19975,ko:K19976 ko02010,ko02020,map02010,map02020 M00243,M00316,M00317,M00318,M00791,M00792 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.1,3.A.1.15.14,3.A.1.15.15,3.A.1.15.2,3.A.1.15.6,3.A.1.15.7,3.A.1.15.9 iECED1_1282.ECED1_1296 Bacteria 1TRKU@1239,4HAKT@91061,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family BNPNBKBE_01898 1046629.Ssal_01396 2.3e-132 478.4 Bacilli mtsC GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 ko:K09819,ko:K11705,ko:K19972,ko:K19975,ko:K19976 ko02010,map02010 M00243,M00318,M00791,M00792 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.14,3.A.1.15.15,3.A.1.15.2,3.A.1.15.6 Bacteria 1TPZB@1239,4HBD7@91061,COG1108@1,COG1108@2 NA|NA|NA P ABC-type Mn2 Zn2 transport systems, permease components BNPNBKBE_01899 1046629.Ssal_01395 1.2e-124 452.6 Bacilli sitB 3.6.3.35 ko:K09817,ko:K10830,ko:K11706,ko:K11710,ko:K19973 ko02010,map02010 M00242,M00318,M00319,M00791,M00792 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.14,3.A.1.15.15,3.A.1.15.2,3.A.1.15.3,3.A.1.15.5,3.A.1.15.6 Bacteria 1TQJ3@1239,4HA2W@91061,COG1121@1,COG1121@2 NA|NA|NA P ABC transporter, ATP-binding protein BNPNBKBE_01900 1046629.Ssal_01394 2e-74 285.4 Bacilli ko:K16924,ko:K16927 M00582 ko00000,ko00002,ko02000 3.A.1.29,3.A.1.32 Bacteria 1V5GD@1239,4HI8Y@91061,COG4720@1,COG4720@2 NA|NA|NA S Psort location CytoplasmicMembrane, score BNPNBKBE_01901 1046629.Ssal_01392 2.4e-63 248.1 Bacilli Bacteria 1VF26@1239,2DNM7@1,32Y2X@2,4HP82@91061 NA|NA|NA S Domain of unknown function (DUF4430) BNPNBKBE_01902 1046629.Ssal_01391 0.0 1817.0 Bacilli ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 iJN678.ppc,iSFV_1184.SFV_4025 Bacteria 1TQB6@1239,4HCAF@91061,COG2352@1,COG2352@2 NA|NA|NA H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle BNPNBKBE_01903 1046629.Ssal_01390 3e-182 644.4 Bacilli holA 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TRM0@1239,4HBB4@91061,COG1466@1,COG1466@2 NA|NA|NA L DNA polymerase III delta subunit BNPNBKBE_01904 1046629.Ssal_01389 2.7e-111 407.9 Bacilli sodA GO:0005575,GO:0005576 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Bacteria 1TPXT@1239,4HA6U@91061,COG0605@1,COG0605@2 NA|NA|NA C radicals which are normally produced within the cells and which are toxic to biological systems BNPNBKBE_01905 904306.HMPREF9192_1182 6.4e-164 583.9 Bacilli 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1VHF8@1239,4HU1N@91061,COG2367@1,COG2367@2 NA|NA|NA V D-alanyl-D-alanine carboxypeptidase BNPNBKBE_01906 1046629.Ssal_01387 1.2e-99 369.4 Bacilli pilD 3.4.23.43 ko:K02236,ko:K02506,ko:K02654 M00331,M00429 ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 Bacteria 1TQY4@1239,4HCC3@91061,COG1989@1,COG1989@2 NA|NA|NA NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases BNPNBKBE_01907 1046629.Ssal_01386 4.5e-78 297.4 Bacilli dps ko:K04047 ko00000,ko03036 Bacteria 1VCVJ@1239,4HMBD@91061,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family BNPNBKBE_01908 1046629.Ssal_01385 3.8e-78 297.4 Bacilli perR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K03711,ko:K09825 ko00000,ko03000 Bacteria 1V400@1239,4HHF8@91061,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family BNPNBKBE_01909 435842.HMPREF0848_00386 4.2e-27 126.7 Bacilli yqgQ Bacteria 1VK83@1239,4HRG2@91061,COG4483@1,COG4483@2 NA|NA|NA S protein conserved in bacteria BNPNBKBE_01910 1046629.Ssal_01383 1.1e-175 622.5 Bacilli glk GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS07790 Bacteria 1TPKW@1239,4HBAU@91061,COG1940@1,COG1940@2 NA|NA|NA G Glucokinase BNPNBKBE_01911 1046629.Ssal_01382 0.0 1198.3 Bacilli typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 ko:K06207 ko00000 Bacteria 1TQ5Y@1239,4HAQ6@91061,COG1217@1,COG1217@2 NA|NA|NA T GTP-binding protein TypA BNPNBKBE_01913 1046629.Ssal_01380 2e-247 861.3 Bacilli murD 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TQ3P@1239,4HA5P@91061,COG0771@1,COG0771@2 NA|NA|NA M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) BNPNBKBE_01914 1046629.Ssal_01379 9.8e-197 692.6 Bacilli murG 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 GT28 Bacteria 1TQFT@1239,4HBAQ@91061,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) BNPNBKBE_01915 904306.HMPREF9192_1192 5.3e-132 477.6 Firmicutes divIB ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Bacteria 1VHEY@1239,COG1589@1,COG1589@2 NA|NA|NA D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex BNPNBKBE_01916 1046629.Ssal_01377 3.5e-223 780.8 Bacilli ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Bacteria 1TP1Z@1239,4H9NF@91061,COG0849@1,COG0849@2 NA|NA|NA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring BNPNBKBE_01917 1046629.Ssal_01376 2.8e-233 814.3 Bacilli ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Bacteria 1TP6W@1239,4H9WZ@91061,COG0206@1,COG0206@2 NA|NA|NA D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity BNPNBKBE_01918 1046629.Ssal_01375 1.9e-121 441.8 Bacilli ylmE GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 ko:K06997 ko00000 Bacteria 1TRDN@1239,4HC45@91061,COG0325@1,COG0325@2 NA|NA|NA S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis BNPNBKBE_01919 1046629.Ssal_01374 3.4e-90 337.8 Bacteria sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0044464,GO:0051301,GO:0071840,GO:0071944,GO:0090529 ko:K09772 ko00000,ko03036 Bacteria COG1799@1,COG1799@2 NA|NA|NA D cell septum assembly BNPNBKBE_01920 435842.HMPREF0848_00397 1.7e-30 138.3 Bacteria yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02221 ko00000,ko02044 Bacteria COG0762@1,COG0762@2 NA|NA|NA D integral membrane protein BNPNBKBE_01921 1046629.Ssal_01373 8.6e-137 493.0 Bacilli ylmH ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 Bacteria 1U5V2@1239,4HD3F@91061,COG2302@1,COG2302@2 NA|NA|NA S conserved protein, contains S4-like domain BNPNBKBE_01922 1046629.Ssal_01372 5.5e-137 493.8 Bacilli divIVA ko:K04074 ko00000,ko03036 Bacteria 1V27M@1239,4HG80@91061,COG3599@1,COG3599@2 NA|NA|NA D Cell division initiation protein BNPNBKBE_01923 1046629.Ssal_01371 0.0 1865.5 Bacilli ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_0027,iPC815.YPO0475 Bacteria 1TPS7@1239,4HAWB@91061,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) BNPNBKBE_01924 1046629.Ssal_01369 3.8e-184 650.6 Bacilli nrdF 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1TQTH@1239,4H9WX@91061,COG0208@1,COG0208@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides BNPNBKBE_01925 1046629.Ssal_01368 0.0 1441.4 Bacilli nrdE 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 iYO844.BSU17380 Bacteria 1TPFH@1239,4H9X0@91061,COG0209@1,COG0209@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides BNPNBKBE_01926 264199.stu1269 6.5e-34 149.4 Bacilli nrdH GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009893,GO:0009987,GO:0016491,GO:0019222,GO:0019725,GO:0022900,GO:0042592,GO:0043085,GO:0044093,GO:0044237,GO:0045454,GO:0048518,GO:0050789,GO:0050790,GO:0050794,GO:0051341,GO:0051353,GO:0055114,GO:0065007,GO:0065008,GO:0065009 ko:K06191 ko00000 Bacteria 1VEFX@1239,4HNUX@91061,COG0695@1,COG0695@2 NA|NA|NA O Glutaredoxin BNPNBKBE_01927 1046629.Ssal_01366 0.0 1742.6 Bacilli acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS06730 Bacteria 1VTMM@1239,4HB5N@91061,COG1048@1,COG1048@2 NA|NA|NA C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate BNPNBKBE_01928 1046629.Ssal_01365 2.4e-209 734.6 Bacilli citZ 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TPPS@1239,4H9YE@91061,COG0372@1,COG0372@2 NA|NA|NA C Belongs to the citrate synthase family BNPNBKBE_01929 1046629.Ssal_01364 7.7e-219 766.1 Bacilli icd GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144 Bacteria 1UHPE@1239,4H9US@91061,COG0538@1,COG0538@2 NA|NA|NA C Isocitrate dehydrogenase BNPNBKBE_01930 1046629.Ssal_01363 3e-38 164.1 Bacilli ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 ko:K11189 ko00000,ko02000 4.A.2.1 Bacteria 1VA0R@1239,4HKGA@91061,COG1925@1,COG1925@2 NA|NA|NA G phosphocarrier protein Hpr BNPNBKBE_01931 1046629.Ssal_01362 0.0 1096.6 Bacilli ptsI GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0008965,GO:0009401,GO:0016740,GO:0016772,GO:0016775,GO:0019197,GO:0032991,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 8.A.7 iB21_1397.B21_02277,iE2348C_1286.E2348C_2602,iEC042_1314.EC042_2625,iECBD_1354.ECBD_1265,iECB_1328.ECB_02316,iECD_1391.ECD_02316,iECH74115_1262.ECH74115_3647,iECIAI1_1343.ECIAI1_2474,iECIAI39_1322.ECIAI39_2562,iECO103_1326.ECO103_2935,iECO111_1330.ECO111_3146,iECO26_1355.ECO26_3469,iECP_1309.ECP_2440,iECSE_1348.ECSE_2707,iECSP_1301.ECSP_3364,iECUMN_1333.ECUMN_2738,iECW_1372.ECW_m2645,iECs_1301.ECs3288,iEKO11_1354.EKO11_1312,iEcE24377_1341.EcE24377A_2703,iEcHS_1320.EcHS_A2551,iEcSMS35_1347.EcSMS35_2571,iEcolC_1368.EcolC_1262,iLF82_1304.LF82_1770,iNRG857_1313.NRG857_12115,iSBO_1134.SBO_2440,iSDY_1059.SDY_2613,iSFV_1184.SFV_2468,iSF_1195.SF2471,iSFxv_1172.SFxv_2720,iSSON_1240.SSON_2505,iS_1188.S2617,iUMNK88_1353.UMNK88_3018,iWFL_1372.ECW_m2645,iZ_1308.Z3682 Bacteria 1TPK8@1239,4H9VD@91061,COG1080@1,COG1080@2 NA|NA|NA G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) BNPNBKBE_01932 1046629.Ssal_01360 6.6e-265 919.5 Bacilli gapN GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0043891,GO:0047100,GO:0055114 1.2.1.9 ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 M00308,M00633 R01058 RC00242 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4S@1239,4H9MF@91061,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family BNPNBKBE_01933 1046629.Ssal_01359 3.9e-161 573.9 Bacilli XK27_05670 ko:K07017 ko00000 Bacteria 1UZZZ@1239,4HCWE@91061,COG2819@1,COG2819@2 NA|NA|NA S Putative esterase BNPNBKBE_01934 1046629.Ssal_01358 2.7e-153 547.7 Bacilli XK27_05675 Bacteria 1TSKW@1239,4HB4B@91061,COG4947@1,COG4947@2 NA|NA|NA S Esterase BNPNBKBE_01935 1046629.Ssal_01357 5.4e-225 786.6 Bacilli XK27_05680 6.3.2.2,6.3.2.4 ko:K01919,ko:K01921 ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,map00270,map00473,map00480,map00550,map01100,map01502 M00118 R00894,R01150,R10993 RC00064,RC00090,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011 Bacteria 1UIK5@1239,4HBFS@91061,COG1181@1,COG1181@2 NA|NA|NA M carbamoylphosphate synthase large subunit BNPNBKBE_01936 1046629.Ssal_01356 6e-178 630.2 Bacilli yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TQ9R@1239,4HANR@91061,COG0513@1,COG0513@2 NA|NA|NA L DEAD DEAH box helicase BNPNBKBE_01937 1046629.Ssal_01355 3.1e-113 414.5 Bacilli udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 iSBO_1134.SBO_0893 Bacteria 1TQ4V@1239,4HAVR@91061,COG0572@1,COG0572@2 NA|NA|NA F Cytidine monophosphokinase BNPNBKBE_01938 1046629.Ssal_01354 0.0 1092.0 Bacilli uup ko:K06158 ko00000,ko03012 Bacteria 1TPAX@1239,4HBVV@91061,COG0488@1,COG0488@2 NA|NA|NA S abc transporter atp-binding protein BNPNBKBE_01939 435842.HMPREF0848_00417 1.6e-39 168.3 Bacilli MA20_06245 Bacteria 1VCHF@1239,4HMAW@91061,COG4298@1,COG4298@2 NA|NA|NA S yiaA/B two helix domain BNPNBKBE_01940 1046629.Ssal_01352 9.7e-132 476.1 Bacilli pip 1.11.1.10 ko:K00433 ko00000,ko01000 Bacteria 1V02M@1239,4HN2K@91061,COG0596@1,COG0596@2 NA|NA|NA S Alpha beta hydrolase BNPNBKBE_01941 1046629.Ssal_01351 0.0 1622.1 Bacilli mprF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 ko:K07027,ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 2.A.1.3.37,4.D.2 iYO844.BG12900 Bacteria 1TQI2@1239,4HBHU@91061,COG0392@1,COG0392@2,COG2898@1,COG2898@2 NA|NA|NA J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms BNPNBKBE_01942 1046629.Ssal_01350 8.1e-148 529.6 Bacilli cobQ ko:K07009 ko00000 Bacteria 1U7I9@1239,4HD1P@91061,COG3442@1,COG3442@2 NA|NA|NA S glutamine amidotransferase BNPNBKBE_01943 1046629.Ssal_01349 1.2e-252 878.6 Bacilli murD 3.4.21.10,6.3.2.13,6.3.2.9 ko:K01317,ko:K01925,ko:K01928,ko:K01932 ko00300,ko00471,ko00550,ko01100,map00300,map00471,map00550,map01100 R02783,R02788 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01002,ko01011,ko04131 Bacteria 1UHPI@1239,4HVP0@91061,COG0771@1,COG0771@2 NA|NA|NA M Mur ligase, middle domain protein BNPNBKBE_01944 904306.HMPREF9192_1521 2.7e-149 534.6 Bacilli dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 ko00000,ko01000 Bacteria 1TPRW@1239,4H9XZ@91061,COG1624@1,COG1624@2 NA|NA|NA S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria BNPNBKBE_01945 1046629.Ssal_01347 3.2e-162 577.8 Bacilli ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 Bacteria 1TSIV@1239,4HD8Y@91061,COG4856@1,COG4856@2 NA|NA|NA S Protein conserved in bacteria BNPNBKBE_01946 1046629.Ssal_01346 1.3e-249 868.6 Bacilli glmM GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 R02060 RC00408 ko00000,ko00001,ko01000 iSB619.SA_RS11275,iSBO_1134.SBO_3206 Bacteria 1TP1X@1239,4HB16@91061,COG1109@1,COG1109@2 NA|NA|NA G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate BNPNBKBE_01947 1046629.Ssal_01345 1.3e-64 252.3 Bacilli gtrA GO:0000166,GO:0003674,GO:0003824,GO:0003870,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009987,GO:0016020,GO:0016410,GO:0016491,GO:0016620,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0016903,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 Bacteria 1VMS6@1239,4HNB7@91061,COG2246@1,COG2246@2 NA|NA|NA S GtrA-like protein BNPNBKBE_01948 1046629.Ssal_01344 3.7e-120 437.6 Bacilli trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 ko00000,ko01000,ko03016 Bacteria 1V3I4@1239,4HHIM@91061,COG2384@1,COG2384@2 NA|NA|NA S SAM-dependent methyltransferase BNPNBKBE_01949 1046629.Ssal_01343 1.3e-142 512.3 Bacilli yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.16 ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ27@1239,4H9NY@91061,COG0327@1,COG0327@2 NA|NA|NA S Belongs to the GTP cyclohydrolase I type 2 NIF3 family BNPNBKBE_01950 1046629.Ssal_01342 1.1e-144 519.2 Bacilli zupT ko:K07238 ko00000,ko02000 2.A.5.5 Bacteria 1TP7J@1239,4HB3R@91061,COG0428@1,COG0428@2 NA|NA|NA P Mediates zinc uptake. May also transport other divalent cations BNPNBKBE_01951 1046629.Ssal_01341 1.3e-193 682.2 Bacilli yurR GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 1.4.5.1 ko:K00285 ko00360,map00360 R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 Bacteria 1TQTF@1239,4HA0F@91061,COG0665@1,COG0665@2 NA|NA|NA E oxidoreductase BNPNBKBE_01952 1046629.Ssal_01340 2.6e-255 887.5 Bacilli Bacteria 1TRER@1239,4IQ64@91061,COG4099@1,COG4099@2 NA|NA|NA S phospholipase Carboxylesterase BNPNBKBE_01953 1046629.Ssal_01339 2.4e-161 574.7 Bacilli rfbA GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0334 Bacteria 1V301@1239,4H9R0@91061,COG1209@1,COG1209@2 NA|NA|NA M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis BNPNBKBE_01954 1046629.Ssal_01338 6.4e-113 413.3 Bacilli rmlC 1.1.1.133,5.1.3.13 ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777,R06514 RC00182,RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 1TRVB@1239,4HFQB@91061,COG1898@1,COG1898@2 NA|NA|NA M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose BNPNBKBE_01955 435842.HMPREF0848_00434 1.3e-204 718.8 Bacilli rfbB GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPWM@1239,4HA3Y@91061,COG1088@1,COG1088@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily BNPNBKBE_01957 888833.HMPREF9421_0631 1.7e-30 139.8 Bacteria Bacteria COG4640@1,COG4640@2 NA|NA|NA KT response to antibiotic BNPNBKBE_01958 1046629.Ssal_01332 5e-215 753.4 Bacilli hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 Bacteria 1TPES@1239,4HA60@91061,COG0635@1,COG0635@2 NA|NA|NA H Involved in the biosynthesis of porphyrin-containing compound BNPNBKBE_01959 1046629.Ssal_01331 1.1e-141 509.2 Bacilli fat 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 Bacteria 1V3RB@1239,4HHJ4@91061,COG3884@1,COG3884@2 NA|NA|NA I Acyl-ACP thioesterase BNPNBKBE_01960 1046629.Ssal_01330 1.5e-138 498.8 Bacilli nagD 2.7.1.25,3.1.3.41 ko:K00860,ko:K01101 ko00230,ko00627,ko00920,ko01100,ko01120,map00230,map00627,map00920,map01100,map01120 M00176 R00509,R03024,R04928 RC00002,RC00078,RC00151 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQGM@1239,4HA3R@91061,COG0647@1,COG0647@2 NA|NA|NA G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro BNPNBKBE_01961 435842.HMPREF0848_00440 3.5e-117 427.6 Bacilli ylfI Bacteria 1VGZ1@1239,4HNTM@91061,COG4478@1,COG4478@2 NA|NA|NA S tigr01906 BNPNBKBE_01962 435842.HMPREF0848_00441 6.3e-134 483.4 Bacilli hisK 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V77D@1239,4HGYX@91061,COG1387@1,COG1387@2 NA|NA|NA E Histidinol phosphatase and related hydrolases of the PHP family BNPNBKBE_01963 435842.HMPREF0848_00448 4e-146 524.2 Bacilli XK27_08080 3.1.1.53 ko:K05970 ko00000,ko01000 Bacteria 1TR6Z@1239,4HGB0@91061,COG4632@1,COG4632@2 NA|NA|NA G Exopolysaccharide biosynthesis protein BNPNBKBE_01964 435842.HMPREF0848_00449 4.5e-59 233.8 Firmicutes XK27_08085 Bacteria 1VM50@1239,2EJUK@1,33DJ8@2 NA|NA|NA BNPNBKBE_01965 435842.HMPREF0848_00450 3.2e-192 677.6 Bacilli hisC 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 iJN678.hisC Bacteria 1TPUV@1239,4HA1H@91061,COG0079@1,COG0079@2 NA|NA|NA E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily BNPNBKBE_01966 435842.HMPREF0848_00451 4.1e-181 640.6 Bacilli hisZ 2.4.2.17,6.1.1.21 ko:K00765,ko:K01892,ko:K02502 ko00340,ko00970,ko01100,ko01110,ko01230,map00340,map00970,map01100,map01110,map01230 M00026,M00359,M00360 R01071,R03655 RC00055,RC00523,RC02819,RC03200 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPZZ@1239,4HBBA@91061,COG3705@1,COG3705@2 NA|NA|NA E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine BNPNBKBE_01967 435842.HMPREF0848_00452 8e-117 426.4 Bacilli hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSVZ@1239,4H9MH@91061,COG0040@1,COG0040@2 NA|NA|NA E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity BNPNBKBE_01968 1046629.Ssal_01322 3e-232 810.8 Bacilli hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 ko:K00013,ko:K15509 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAW@1239,4H9XK@91061,COG0141@1,COG0141@2 NA|NA|NA E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine BNPNBKBE_01969 435842.HMPREF0848_00454 8.8e-107 392.9 Bacilli hisB GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,2.6.1.9,3.1.3.15,4.2.1.19 ko:K00013,ko:K00817,ko:K01089,ko:K01693 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R01158,R01163,R03012,R03013,R03243,R03457 RC00006,RC00017,RC00099,RC00242,RC00463,RC00888,RC00932 ko00000,ko00001,ko00002,ko01000,ko01007 iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iLJ478.TM1039,iSB619.SA_RS14130,iUMNK88_1353.UMNK88_2570 Bacteria 1TRH7@1239,4HCFG@91061,COG0131@1,COG0131@2 NA|NA|NA E imidazoleglycerol-phosphate dehydratase BNPNBKBE_01970 435842.HMPREF0848_00455 8.8e-110 402.9 Bacilli hisH ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQT0@1239,4HHNQ@91061,COG0118@1,COG0118@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR BNPNBKBE_01971 1046629.Ssal_01319 1.7e-128 465.3 Bacilli hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0388 Bacteria 1V1IR@1239,4HACP@91061,COG0106@1,COG0106@2 NA|NA|NA E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase BNPNBKBE_01972 435842.HMPREF0848_00457 9.6e-138 496.1 Bacilli hisF GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 3.5.4.19,3.6.1.31 ko:K01663,ko:K02500,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04558 RC00002,RC00010,RC01055,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 iECO111_1330.ECO111_2749,iEcolC_1368.EcolC_1617,iHN637.CLJU_RS05755,iLJ478.TM1036,iSB619.SA_RS14115,iYL1228.KPN_02481 Bacteria 1TP0W@1239,4HAAM@91061,COG0107@1,COG0107@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit BNPNBKBE_01973 435842.HMPREF0848_00458 1.8e-59 235.0 Bacilli hisI GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.5.4.25,3.6.1.31,5.3.1.16 ko:K01496,ko:K01497,ko:K01814,ko:K11755 ko00340,ko00740,ko00790,ko01100,ko01110,ko01230,ko02024,map00340,map00740,map00790,map01100,map01110,map01230,map02024 M00026,M00125 R00425,R04035,R04037,R04640 RC00002,RC00293,RC00945,RC01055,RC02504 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_0880,iECW_1372.ECW_m2186,iEKO11_1354.EKO11_1768,iHN637.CLJU_RS05760,iSB619.SA_RS14110,iUMN146_1321.UM146_06665,iWFL_1372.ECW_m2186 Bacteria 1UYNA@1239,4HA9R@91061,COG0139@1,COG0139@2 NA|NA|NA E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP BNPNBKBE_01974 1046629.Ssal_01315 4.1e-50 203.8 Bacteria hisE GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16 ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04640 RC00002,RC00945,RC01055 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS14110,iYO844.BSU34860 Bacteria COG0140@1,COG0140@2 NA|NA|NA E phosphoribosyl-ATP diphosphatase activity BNPNBKBE_01976 1046629.Ssal_01313 3.8e-93 347.8 Firmicutes XK27_05505 Bacteria 1V1GI@1239,COG1285@1,COG1285@2 NA|NA|NA S Psort location CytoplasmicMembrane, score BNPNBKBE_01977 435842.HMPREF0848_00461 6.3e-145 520.0 Bacilli Bacteria 1V1FZ@1239,4HJFI@91061,COG5036@1,COG5036@2 NA|NA|NA P molecular chaperone BNPNBKBE_01978 904306.HMPREF9192_1548 1.9e-98 366.3 Bacilli Bacteria 1TZ8N@1239,2Z8AD@2,4HV65@91061,arCOG08054@1 NA|NA|NA S Carbohydrate-binding domain-containing protein Cthe_2159 BNPNBKBE_01979 1046629.Ssal_01310 3e-171 607.8 Bacilli XK27_08075 Bacteria 1UIHV@1239,4ISID@91061,COG1216@1,COG1216@2,COG2246@1,COG2246@2 NA|NA|NA M glycosyl transferase family 2 BNPNBKBE_01980 1046629.Ssal_01309 0.0 2320.4 Bacilli 2.4.1.5 ko:K00689,ko:K20276 ko00500,ko02020,ko02024,map00500,map02020,map02024 R02120,R06066 RC00028 ko00000,ko00001,ko01000 GH13 Bacteria 1VQXK@1239,4HEIA@91061,COG0366@1,COG0366@2,COG5263@1,COG5263@2 NA|NA|NA M KxYKxGKxW signal domain protein BNPNBKBE_01981 1046629.Ssal_01308 0.0 2515.7 Bacilli 2.4.1.5 ko:K00689,ko:K20276 ko00500,ko02020,ko02024,map00500,map02020,map02024 R02120,R06066 RC00028 ko00000,ko00001,ko01000 GH13 Bacteria 1VQXK@1239,4HEIA@91061,COG0366@1,COG0366@2,COG5263@1,COG5263@2 NA|NA|NA M KxYKxGKxW signal domain protein BNPNBKBE_01982 1046629.Ssal_01307 0.0 2737.6 Bacilli 2.4.1.5 ko:K00689,ko:K20276 ko00500,ko02020,ko02024,map00500,map02020,map02024 R02120,R06066 RC00028 ko00000,ko00001,ko01000 GH13 Bacteria 1VQXK@1239,4HEIA@91061,COG0366@1,COG0366@2,COG5263@1,COG5263@2 NA|NA|NA M KxYKxGKxW signal domain protein BNPNBKBE_01983 904306.HMPREF9192_1554 3.2e-227 794.3 Bacilli rodA ko:K05837 ko00000,ko03036 Bacteria 1TPGH@1239,4HAV4@91061,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family BNPNBKBE_01984 1046629.Ssal_01305 5.1e-243 846.7 Bacilli hflX GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 ko:K03665 ko00000,ko03009 Bacteria 1TNZB@1239,4HACA@91061,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis BNPNBKBE_01985 904306.HMPREF9192_1556 1.4e-113 415.6 Bacilli galT 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1VY8D@1239,4HXPD@91061,COG4468@1,COG4468@2 NA|NA|NA G UDPglucose--hexose-1-phosphate uridylyltransferase BNPNBKBE_01986 904306.HMPREF9192_1557 2.7e-174 617.8 Bacilli rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 1TRGP@1239,4HABM@91061,COG1234@1,COG1234@2 NA|NA|NA S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA BNPNBKBE_01987 904306.HMPREF9192_1558 2.2e-134 485.0 Bacilli XK27_05435 1.1.1.100 ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TSJ3@1239,4HDU5@91061,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family BNPNBKBE_01988 888048.HMPREF8577_0864 7.5e-21 105.5 Bacilli Bacteria 1V1BN@1239,4HPJN@91061,COG0500@1,COG0500@2 NA|NA|NA Q Methyltransferase domain BNPNBKBE_01989 888833.HMPREF9421_1624 3.7e-64 250.8 Bacteria GnaT 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 Bacteria COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase BNPNBKBE_01990 1046629.Ssal_01299 0.0 1415.6 Bacilli recJ ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPXE@1239,4H9UP@91061,COG0608@1,COG0608@2,COG4199@1,COG4199@2 NA|NA|NA L Single-strand DNA-specific exonuclease, C terminal domain BNPNBKBE_01991 904306.HMPREF9192_1561 4.9e-93 347.1 Bacilli apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 Bacteria 1V1BV@1239,4HFUA@91061,COG0503@1,COG0503@2 NA|NA|NA F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis BNPNBKBE_01992 1046629.Ssal_01297 9.3e-183 646.0 Bacilli metA GO:0003674,GO:0003824,GO:0008374,GO:0008899,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQVR@1239,4H9W4@91061,COG1897@1,COG1897@2 NA|NA|NA E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine BNPNBKBE_01993 1046629.Ssal_01296 1.3e-125 455.7 Bacteria dnaD ko:K02086 ko00000 Bacteria COG3935@1,COG3935@2 NA|NA|NA BNPNBKBE_01994 1046629.Ssal_01295 4.2e-118 430.6 Bacilli nth 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TRAK@1239,4HATD@91061,COG0177@1,COG0177@2 NA|NA|NA L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate BNPNBKBE_01996 1046629.Ssal_01292 1.4e-232 812.0 Bacilli xseA 3.1.11.6 ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP4E@1239,4HAN2@91061,COG1570@1,COG1570@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides BNPNBKBE_01997 435842.HMPREF0848_00499 4.6e-29 133.3 Firmicutes xseB 3.1.11.6 ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1VK9I@1239,COG1722@1,COG1722@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides BNPNBKBE_01998 1046629.Ssal_01290 3.4e-155 554.3 Bacilli ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 ko:K00795,ko:K02523,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061,R09248 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1TPQY@1239,4HA8E@91061,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family BNPNBKBE_01999 1046629.Ssal_01289 4.7e-146 523.9 Bacilli rrmJ 2.1.1.226,2.1.1.227 ko:K06442 ko00000,ko01000,ko03009 Bacteria 1TPE4@1239,4HAPY@91061,COG1189@1,COG1189@2 NA|NA|NA J Ribosomal RNA large subunit methyltransferase J BNPNBKBE_02000 1046629.Ssal_01288 7.5e-74 283.1 Bacilli argR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 ko:K03402 ko00000,ko03000 Bacteria 1V1R7@1239,4HFY8@91061,COG1438@1,COG1438@2 NA|NA|NA K Regulates arginine biosynthesis genes BNPNBKBE_02001 1046629.Ssal_01287 2.9e-296 1023.8 Bacilli recN GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 ko:K03631,ko:K13582 ko04112,map04112 ko00000,ko00001,ko03400 Bacteria 1TP99@1239,4H9ZR@91061,COG0497@1,COG0497@2 NA|NA|NA L May be involved in recombinational repair of damaged DNA BNPNBKBE_02002 1046629.Ssal_01286 2e-144 518.5 Bacilli DegV Bacteria 1TRZ4@1239,4HBR8@91061,COG1307@1,COG1307@2 NA|NA|NA S DegV family BNPNBKBE_02003 1046629.Ssal_01285 1.2e-155 555.8 Bacilli ypmR GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0016298,GO:0016787,GO:0016788,GO:0052689 Bacteria 1V1HR@1239,4HDXS@91061,COG2755@1,COG2755@2 NA|NA|NA E COG2755 Lysophospholipase L1 and related esterases BNPNBKBE_02004 1046629.Ssal_01284 3.4e-95 354.4 Bacilli ypmS Bacteria 1VF0K@1239,4HIYN@91061,COG4698@1,COG4698@2 NA|NA|NA S Protein conserved in bacteria BNPNBKBE_02005 1046629.Ssal_01283 6.3e-39 166.4 Bacilli hup ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 1V9XQ@1239,4HKF2@91061,COG0776@1,COG0776@2 NA|NA|NA L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions BNPNBKBE_02007 1046629.Ssal_01281 4e-178 630.6 Bacilli pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPFV@1239,4HBFE@91061,COG0167@1,COG0167@2 NA|NA|NA F Catalyzes the conversion of dihydroorotate to orotate BNPNBKBE_02008 997830.HMPREF1124_2001 3.6e-131 474.2 Streptococcus infantis gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1TQFP@1239,43G3N@68892,4HAW7@91061,COG0588@1,COG0588@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate BNPNBKBE_02009 435842.HMPREF0848_00511 2.1e-288 997.7 Bacilli leuA 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS10690,iYO844.BSU28280 Bacteria 1TP4Y@1239,4HA6E@91061,COG0119@1,COG0119@2 NA|NA|NA E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) BNPNBKBE_02010 1046629.Ssal_01275 2.5e-189 667.9 Bacilli leuB GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TPEM@1239,4HATP@91061,COG0473@1,COG0473@2 NA|NA|NA CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate BNPNBKBE_02011 1046629.Ssal_01273 2.8e-276 957.2 Bacilli leuC GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 iEcE24377_1341.EcE24377A_0075,iPC815.YPO0531,iSB619.SA_RS10700 Bacteria 1TPE5@1239,4HAWA@91061,COG0065@1,COG0065@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate BNPNBKBE_02012 1046629.Ssal_01272 2.4e-112 411.4 Bacilli leuD 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1V1I6@1239,4HFTY@91061,COG0066@1,COG0066@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate BNPNBKBE_02013 1046629.Ssal_01271 0.0 1998.8 Bacilli dnaE 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPYG@1239,4H9T3@91061,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase BNPNBKBE_02014 1046629.Ssal_01270 3.6e-188 664.1 Bacilli pfkA GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 iYO844.BSU29190 Bacteria 1TPF4@1239,4HAPN@91061,COG0205@1,COG0205@2 NA|NA|NA F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis BNPNBKBE_02015 1046629.Ssal_01268 6e-277 959.5 Bacilli pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009986,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0022607,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40,2.7.7.4 ko:K00873,ko:K00958 ko00010,ko00230,ko00261,ko00450,ko00620,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00261,map00450,map00620,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050,M00176,M00596 R00200,R00430,R00529,R01138,R01858,R02320,R04929 RC00002,RC00015,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iECO103_1326.ECO103_1819,iPC815.YPO2393 Bacteria 1TPGG@1239,4H9VY@91061,COG0469@1,COG0469@2 NA|NA|NA G Belongs to the pyruvate kinase family BNPNBKBE_02016 1046629.Ssal_01225 3.2e-110 404.4 Bacilli tcyB_2 ko:K02029,ko:K02030,ko:K10040,ko:K17073,ko:K17074 ko02010,map02010 M00228,M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1V14N@1239,4HJ9W@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter (permease) BNPNBKBE_02017 904306.HMPREF9192_1622 2e-155 555.1 Bacilli endA ko:K15051 ko00000 Bacteria 1V4X2@1239,4HIF5@91061,COG2169@1,COG2169@2 NA|NA|NA F DNA RNA non-specific endonuclease BNPNBKBE_02018 1046629.Ssal_01228 7.2e-26 122.5 Bacilli epuA Bacteria 1VMAH@1239,2EK0E@1,33DQZ@2,4HRG1@91061 NA|NA|NA S DNA-directed RNA polymerase subunit beta BNPNBKBE_02019 1046629.Ssal_01229 5.5e-231 806.6 Bacilli murA 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 Bacteria 1TPAU@1239,4H9KI@91061,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine BNPNBKBE_02020 435842.HMPREF0848_00551 1e-193 682.6 Bacilli Bacteria 1VCBY@1239,4IPTW@91061,COG3405@1,COG3405@2 NA|NA|NA G Belongs to the glycosyl hydrolase 8 (cellulase D) family BNPNBKBE_02021 435842.HMPREF0848_00550 7.4e-247 859.4 Bacilli ydaM Bacteria 1TRCI@1239,4HAAK@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferases, probably involved in cell wall biogenesis BNPNBKBE_02023 435842.HMPREF0848_00549 1e-131 476.1 Bacilli Bacteria 1W0IB@1239,2DSSB@1,33H90@2,4HYWM@91061 NA|NA|NA BNPNBKBE_02024 435842.HMPREF0848_00548 2.5e-214 751.1 Bacilli mnaA 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 1TQZT@1239,4HBI3@91061,COG0381@1,COG0381@2 NA|NA|NA G Belongs to the UDP-N-acetylglucosamine 2-epimerase family BNPNBKBE_02026 904306.HMPREF9192_1022 1.2e-10 73.2 Bacilli sraP ko:K18491,ko:K21449 ko04550,map04550 ko00000,ko00001,ko02000,ko03000 1.B.40.2 Bacteria 1VIS5@1239,4HIVX@91061,COG5295@1,COG5295@2 NA|NA|NA UW domain, Protein # 1848 queries scanned # Total time (seconds): 4.9441921711 # Rate: 373.77 q/s