LOCUS       c00010_JAHAGE0..        5472 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAHAGE010000006.1 Streptococcus salivarius isolate
            L2_057_061G1_dasL2_057_061G1_maxbin2.maxbin.007
            L2_057_061G1_scaffold_113, whole genome shotgun sequence.
ACCESSION   JAHAGE010000006
VERSION     JAHAGE010000006
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-19 19:06:29
            Original ID  :: JAHAGE010000006.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 22392
            Orig. end    :: 27864
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5472
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[27392:27863](-)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5471)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
     cand_cluster    1..5472
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5472
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="butyrolactone"
                     /region_number="1"
                     /rules="AfsA"
                     /tool="antismash"
     CDS             complement(305..1093)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     118.6; E-value: 5.1e-36)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_29"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 4e-07, bitscore:
                     20.6, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIAICKGENSLEQTKNYTCITGASAGIGAETARQFAKLGMNLIL
                     IARRQERLEKLKQEILNHYPDLDVVIKVVDLSKSSNVFELYESLKKYHITTLINNAGFG
                     NYDKVEYQDLEKIITLIHLNIEALTILSTLYVRDYKDCKGAQLINLSSRGGYMMVPNAV
                     TYCASKFYVSAFTEGLALELEANQHQLKAKVLAPAATKTEFGQVATDSKEYNYDEHFAK
                     YHTSEEMAQFLMELYQSDKVVGLVDVTNFEFHLSGPLLNH"
     CDS             complement(1074..2333)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124:acetyl-CoA acetyltransferase (Score: 496.9;
                     E-value: 5.4e-151)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_30"
                     /transl_table=11
                     /translation="MLTMVCTQVCNFVSTNRKEVANMKRIFIVGAKRTPIGKFGGSLST
                     FSASELGAKVISAVLKQSKLPKEKIDQILIGNVLQAGQGQNPARTASRLAGLPESIPAI
                     TINDVCGSGLSSVNLGASLIMSGQAEVVLVGGMESMSNAPYLLDKARVGYKMGDGILID
                     SMLKDSLIDSIGNYHMGMTAENISSKYSITRGEMDKYAVESHQKATYTTEYGGFKKEIV
                     DIIVDNRKGRNLIVTDENIRSDTSIEKLAKLKSAFKESGVVTAGNSSSINDGASILMLV
                     SEKILYDYKLTPLAEWIDSSLVGLEPRLMGIGPEIAVKKLLTQQKMDITDIDIFELNEA
                     FAAQSIACIRQLGINDMDKVNPKGGAIALGHPVGASGSRILTTLIYELIENKGNYGIAS
                     LCIGSGMGAATLIKNANSNL"
     CDS             complement(2302..3048)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     149.2; E-value: 2.4e-45)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_31"
                     /transl_table=11
                     /translation="MNKKIAIVTGATGSIGYKIVESLISNNYKVIAFAQNLSKLKNLQN
                     HSPENIEVYSVNLKNLLDIESTFQIIKNKYNTIELLINSAGAGPLGGIREISDINLIEN
                     INLKLLGYIRVSREVIPLMKNANNGRIINIVGTFGKQPSPFFIVGSVINAALLSFTKAL
                     SLELAETNITVNAVNPGAVQSLLWKETINQILASGKKELQFLTDPHLKLVQPEDVARAV
                     LYLADEKNNIITGTSINVDNGVYSGL"
     CDS             complement(3048..3686)
                     /locus_tag="ctg10_32"
                     /transl_table=11
                     /translation="MNLKIMKAPYLAVMEWEVEEGKLDEAAKIWINSKVSNFFENSVLY
                     KGLTKNSLVVLYEVTNFSVIQQFVESDEFKQFVKAQAKYMQSDFHQSIVGLVEDVIRRK
                     QLIPKTKYMQLRSIEVPLSDIDSYLEWRKRRIFEFVKRNDKVTSFLAFHSVFSTVPGVL
                     FVTEFEGNPDEYRASFLTDEYKQIIKEAGHDHIKSGEQGLQTFEYEKVE"
     CDS             complement(3721..4203)
                     /locus_tag="ctg10_33"
                     /transl_table=11
                     /translation="MPLLTIISNKKFSSIEKQEIIKVTTDSVIEKWNVLPDKIQVHISI
                     VGDNEISRGGVSPANPKFGILSRRISVTTDDYYSSPNSNMDLEELVTISIDTWTGLSLG
                     DKTSLVNQLTQYFATKYKISGDNIVIYIREITPENWFQNGISGRNPEFLNKSREVK"
     CDS             complement(4214..5053)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1179:hydrolase (Score: 151.6; E-value: 4.9e-46)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_34"
                     /transl_table=11
                     /translation="LQNKKIGQLLSLKKRLSDFKLLALDMDGTSLDSDGKLPIELINFI
                     NSENFGNLVIVFATGRMPLAVYNPLKMLNISKVVISHNGAVISNLENGNCYYENYVPSE
                     IVQFSINLHKQFQIPLHLNLTNEVITDKITSTSKIYAKHLGIEIKQVDLSTMKENVISL
                     LFLSKKSELDSILKQIKNRFKNFSYVLIPDKNFWLLQILPKNTSKGGGVIQLAKILNIS
                     KEDIISFGDSYNDVEMLRNSGIGIAMGNSCEELKEIADYITLSNDDNGVLKALQNLL"
     CDS             complement(5001..5471)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_35"
                     /sec_met_domain="AfsA (E-value: 2.2e-08, bitscore: 25.4,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="ENVLLSEYETFGKSIAFRAYSDWKELDSDHMSDHVDGIKLFEIIR
                     QGMLAAFHINNLKYDSSLALTNLKIEYFQYIETFIPFIVHIIPINRADGGAMYTVFGVY
                     QEDKLVAKGYLGAYAFRTKEAYRNKRKLLKEGAYNIAEQENWPIIESKKEII"
ORIGIN
        1 aatacgtgtg gagcaagatg acgaggttta caatctttat atggacggaa cagtctatgg
       61 agatttagga aagttagaag aactacttgg taaaatactg gaaaaattgt aaattagtct
      121 acaaaaatac ttctatattt ttaaatatcc taaatatcac agaaaattat aacttaccaa
      181 ggtttaaatc ataatagata gacaaaaagc ttctgaaatc taacatttca gaagcttttt
      241 tcttgtcata aaatggctgc aactattatt attcaataca tattatctct atttaataaa
      301 ataattaatg attaagtagt ggtccactaa gatgaaattc aaaatttgta acatcaacta
      361 aaccaacaac tttgtcactt tgatataatt ccatcaaaaa ttgtgccatc tcttcacttg
      421 tgtgatattt agcaaaatgc tcatcataat tgtattcttt cgaatctgta gcaacttgac
      481 cgaattccgt ttttgtggca gctggagcta aaaccttagc ttttaattga tgttgatttg
      541 cctctagttc caatgccaag ccttctgtaa aagcactgac ataaaattta cttgcacagt
      601 atgtaactgc atttggaacc atcatgtatc cgcctctaga tgataagtta atcaattgag
      661 cgcctttaca atctttataa tctctcacat atagagttga tagaattgtt aaagcttcaa
      721 tgtttagatg gattaatgtt attatctttt ctaaatcttg atattcaacc ttatcataat
      781 ttccaaaacc tgcattattt attagagtag taatgtgata ttttttcaag ctttcataaa
      841 gttcaaaaac attactggac ttcgataaat caacaacttt aataacaaca tctaaatccg
      901 gataatggtt caaaatctct tgcttcaatt tttctagtcg ttcttgacgc cgagcaatta
      961 aaataagatt cattcctaat tttgcaaatt gtcttgctgt ctccgctcct ataccagcac
     1021 tggctccagt aatacaagta taattcttcg tttgttccaa actattttct cctttacaga
     1081 ttgctatttg cattttttat aagagtcgct gctcccattc cgctaccgat acacagagaa
     1141 gcgattccat aatttccttt attttcaatc aactcataaa ttagagtagt cagtattctg
     1201 cttcctgaag ctccaactgg atgccctaaa gcaatggcac cacccttagg attaacctta
     1261 tccatatcat tgattcccaa ttgtcttatg caagctattg attgtgcagc aaatgcttca
     1321 ttcaattcaa agatatcaat atcagttata tccatttttt gctgagtcaa caatttcttt
     1381 acagcaattt ctggtccaat tcccattaat cgaggttcta aacctactaa cgaagaatct
     1441 atccattctg ctaaaggagt taatttgtaa tcataaagaa ttttttctga aactagcata
     1501 aggatagaag caccatcatt tatgcttgac gagtttccag ctgtgactac tcctgactct
     1561 ttaaaagcac tttttagttt tgctaatttt tcaatacttg tatcagagcg aatattttca
     1621 tcagttacaa ttagattcct tccttttcta ttatctacta taatatcaac aatttctttt
     1681 ttgaagcctc catattctgt tgtataagtc gccttctgat gactttcaac agcatattta
     1741 tccatttctc cccttgtaat agaatattta gatgaaatgt tttctgctgt cattcccatg
     1801 tgataatttc caatagaatc aataagagaa tctttgagca tggaatcaat taaaatacca
     1861 tctcccattt tgtatcctac tcttgcttta tctagtaagt atggagcatt agacatactc
     1921 tccattcctc caactaaaac aacttccgct tgtcctgaca taataagaga agcacctaaa
     1981 ttaacacttg acaagcctga accacacaca tcattaatgg taattgctgg tatggattct
     2041 ggaagtcctg ctaaacgact tgctgttcta gctggatttt gtccttgacc tgcctgcaat
     2101 acattcccta tcaatatttg gtcaattttt tctttaggta atttagattg tttaagtact
     2161 gccgatataa cttttgctcc tagttctgaa gctgaaaaag ttgataggct tcctccaaat
     2221 ttacctatag gcgtcctttt agcacctaca ataaatattc ttttcatatt tgccacttct
     2281 tttctatttg tagaaacaaa attacaaacc tgagtacaca ccattgtcaa catttattga
     2341 agttcctgtt attatattat tcttttcatc tgctaaatat aatacagctc gtgcaacatc
     2401 ttctggttga actaatttta agtgtgggtc tgtcagaaat tgtaactctt ttttcccaga
     2461 agctaaaatt tgattaattg tttctttcca aagtaaagat tgaaccgctc caggatttac
     2521 tgcattaacg gtaatatttg tttctgctag ctcaagcgat aaagctttag taaaagatag
     2581 caatgcggca ttaatcactg aacctactat aaaaaacgga cttggctgtt tcccaaaggt
     2641 acctacgata ttaataattc taccattatt tgcattcttc atgaggggaa taacttctcg
     2701 agatacccta atatatccta gtagctttaa attaatattt tctatcaagt taatatctga
     2761 tatttctcgg attcctccta atggaccagc ccccgcacta ttaatcaata attctattgt
     2821 attgtactta ttttttataa tttgaaaggt actttctata tccaacaaat tttttagatt
     2881 aacagaatat acttcaatat tctctggtga atgattttgt aaatttttca attttgataa
     2941 attttgagca aaggcaataa ctttatagtt atttgagatt aacgattcta caatcttata
     3001 tccgatgctt cctgtagcac ctgttacaat cgcaattttt ttattcatta ttccaccttt
     3061 tcatattcaa aagtttgtaa tccttgctca ccacttttaa tatggtcatg acccgcttct
     3121 ttaataattt gtttgtattc atcagtcaaa aaactagctc tgtactcatc aggattccct
     3181 tcaaattcag taacaaatag tactcctggc acagtagaga aaactgaatg aaaagctaga
     3241 aaagaagtaa ctttatcatt tctttttaca aattcaaaga tacggcgctt cctccattct
     3301 aaataagaat caatgtcgga taatggaact tcaattgaac gaagttgcat atattttgtt
     3361 tttggaataa gctgtttacg tctaatcaca tcctctacta atccgacaat agactgatgg
     3421 aaatcacttt gcatgtattt tgcttgagct ttaacaaact gtttaaattc atcactttct
     3481 acaaattgtt ggataactga aaaattcgtt acttcatata aaacaactaa agaatttttt
     3541 gttaatcctt tatataaaac agaattctca aagaaatttg acactttact atttatccat
     3601 attttagctg cttcatctag ttttccctct tctacttccc actccattac tgcaagataa
     3661 ggggctttca taatttttaa attcatggtt atttcctcct tatgttttat accaataaat
     3721 ctatttgact tctcgacttt tatttaagaa ttctggattt cttccactga ttccattttg
     3781 aaaccaattt tcaggggtaa tttctctaat ataaatgaca atattatcgc cagatatttt
     3841 atactttgtc gcaaaatatt gtgttaattg attaactaag ctagttttat ctccaagtga
     3901 taatcctgtc cacgtatcaa ttgagatagt cacaagttcc tctaaatcca tattagaatt
     3961 aggagaggag taatagtcat ctgtcgtaac agagatacgt ctactcaaaa ttccaaactt
     4021 aggattagca ggtgatacac cacctctaga aatttcatta tctcctacaa ttgatatatg
     4081 tacttgaatt ttatcaggaa gtacattcca tttttctata acagaatctg tagtaacttt
     4141 tatgatttct tgtttttcaa tagatgaaaa ttttttattt gaaataatag ttagtaacgg
     4201 cattttctcc tccttatagc agattttgta aggcttttag cactccatta tcatcattac
     4261 ttaacgtaat gtaatcagca atttccttta actcttcaca tgagtttccc attgcaatac
     4321 ctatacccga atttcttaac atttcaacat cattataact atcaccaaaa gatataatat
     4381 cctcttttga tatatttaaa atcttagcaa gttgaatgac acctcctcct tttgatgtat
     4441 ttttaggaag aatttgtaat agccaaaaat ttttatctgg aattaaaaca tatgaaaaat
     4501 ttttaaatct attcttaatt tgttttaaaa tgctatctag ttcacttttt tttgaaagaa
     4561 ataacaatga aattacattt tctttcatgg ttgataaatc cacttgtttt atttcaattc
     4621 ccaagtgctt ggcatatatt ttagatgtcg aggtgatttt atcagttata acttcattag
     4681 ttaaattcaa atgtagaggt atttgaaatt gtttatgtaa attaatagaa aattgaacaa
     4741 tttcacttgg aacataattt tcatagtaac aatttccatt ctctaagttt gaaattacag
     4801 caccattatg tgaaataact actttagaaa tattgagcat ttttaatgga ttgtaaactg
     4861 caagaggcat tctaccagtc gcaaaaacta ttactaaatt accaaagttt tcactattta
     4921 taaagttaat taactctatc ggtagtttac catctgaatc tagacttgtt ccatccatat
     4981 ctaaagcaag aagtttaaaa tcagataatc tcttttttag actcaataat tggccaattt
     5041 tcttgttctg caatattgta agctccttcc tttagtagtt ttcgtttatt tctataagct
     5101 tcttttgttc taaaagcata ggctccaagg taaccttttg caacaagttt atcttcttgg
     5161 tatacaccaa aaacggtata catagctcct ccatcggctc tgttaatagg gataatatga
     5221 acgatgaatg ggataaatgt ttcaatgtat tggaaatatt caatcttcaa attagttaag
     5281 gctaaagatg aatcatactt aagattatta atatgaaatg cagctagcat tccttgccga
     5341 ataatctcaa ataattttat gccatcaaca tggtcagaca tatggtcact atctaattct
     5401 ttccaatccg agtacgctct gaatgcaatg cttttaccaa aagtttcata ttctgacaga
     5461 agaacatttt ct
//
