LOCUS       c00035_JAGZXG0..        5807 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAGZXG010000046.1 Lacticaseibacillus paracasei isolate
            L2_013_015G1_dasL2_013_015G1_metabat.metabat.11
            L2_013_015G1_scaffold_235, whole genome shotgun sequence.
ACCESSION   JAGZXG010000046
VERSION     JAGZXG010000046
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-19 22:32:23
            Original ID  :: JAGZXG010000046.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 11361
            Orig. end    :: 17168
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5807
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[16361:16807]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5446
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..5807
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5807
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             10..1386
                     /locus_tag="ctg35_12"
                     /transl_table=11
                     /translation="MSKYRTETDTLGPVEIPANALWGPQTERSRHNFQAGPLMPMPVIR
                     ALLQLKKAAARANVAADVLPAPKGQLITRAVDALLALPDEKLQKDFPLHVYQTGSGTQT
                     NMNVNEVISHQAAKLNPDLPILPNDDVNHSQSSNDTFPTVMNITAAIAVNQLLHAVNQL
                     CSVLYSKAVTYARVVKIGRTHLQDATPLTFGQEISGWVAMMEHDQIALKQLQPNLFYLA
                     IGGTAVGTGLNADPNFGKIVAGRLSDVYQLPLSAKTNKFAALAAHSEISVVHGAVKTLA
                     ADLLKIANDIRFLASGPRAGYGELRIPANEPGSSIMPGKVNPTQAEALTMAAVRVMGND
                     TTITVAASQGNFELNVYKPVIISTFLESADLLTKTVTSFTEKLAAGLTIHAPHMRALVD
                     HSLMLVTALAPHIGYEKSAAIAQLAEQENLDLKAAAIKSGDVTAAQFDKWVDPLKMTRA
                     "
     CDS             complement(1648..2811)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217:NADH:flavin oxidoreductase/NADH oxidase (Score:
                     282.1; E-value: 9.6e-86)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_13"
                     /transl_table=11
                     /translation="MSGYHFLKRFTFKHQTITLKNRIVIPPMTTRLSFEDGTVTRDEIR
                     YYQQRAGGVGMFITGTANVNALGKGFEGELSVADDRFIPGLSKLAAAMKTGGTKAILQI
                     FSAGRMSNSKILRGEQPVSASAVAAPREGYETPRALTSAEIEATIHDFGQAVRRAILAG
                     FDGIELHGANTCLIQQFYSPNSNRRTDEWGGDRDKRMRFPLAVVHEAEKVIATIADRPF
                     LLGYRISPEELEQPGITLDDTLALIDALKQTKIDYLHVSQSDVWRTSLRNPEDTAIMNE
                     QIRDHVAGAFPVIVVGGLKTPADAEKAADSFDLVAIGHEMIREPHWVQKVLDHDEKAIR
                     YQIAPADLEELGIAPTFLDFIESISGGAKGVPLTTAQSMTSSNVPQD"
     CDS             complement(2837..3586)
                     /NRPS_PKS="Domain: PKS_KR (11-174). E-value: 3.9e-12.
                     Score: 38.2. Matches aSDomain:
                     nrpspksdomains_ctg35_14_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     192.8; E-value: 1.2e-58)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_14"
                     /sec_met_domain="adh_short (E-value: 4.3e-35, bitscore:
                     111.5, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEAVILTVKDKVVVITGASSGIGAATVQVLAEAGAKLVIGARRTE
                     RLAELAASFTDGQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAEL
                     KVNEWERMIDVNIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWA
                     IQAIMDGLRQEQAANHIKTTMISPGAVNTELFSTITDPKRREAVEADEKNNGLSASDVA
                     KAVLYAIDQPANVAINEVLLRPVTQER"
     aSDomain        complement(3065..3553)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg35_14_PKS_KR.1"
                     /evalue="3.90E-12"
                     /label="ctg35_14_PKS_KR.1"
                     /locus_tag="ctg35_14"
                     /protein_end="174"
                     /protein_start="11"
                     /score="38.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVITGASSGIGAATVQVLAEAGAKLVIGARRTERLAELAASFTD
                     GQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEWERMIDV
                     NIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIMDGLRQE
                     "
     aSModule        3065..3553
                     /domains="nrpspksdomains_ctg35_14_PKS_KR.1"
                     /incomplete
                     /locus_tags="ctg35_14"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(3470..3550)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_14_0001"
                     /evalue="1.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg35_14"
                     /protein_end="39"
                     /protein_start="12"
                     /score="14.1"
                     /tool="antismash"
                     /translation="VVITGASSGIGAATVQVLAEAGAKLVI"
     CDS             3776..4729
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     220.3; E-value: 5.2e-67)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_15"
                     /transl_table=11
                     /translation="MKQVRLGGFNWQASSVALGIMRMNVLAPDKAANVLDSAYNDGINF
                     IDSADIYGQGKSEEVFGEALKQASVSRDQLFIQSKVGIVVDPKRSHGSLVFGKRYDFSK
                     DHLLSAVDHILKRLQVDYLDSVLLHRPDPLMEVDDVAAAFDALEQSGKVRHFGVSNFNP
                     EQLALLESGIRQPLLIDQVQFSVAHTGMVNAGMHTNMADAASVDHDGSLLPYLQRKHMT
                     LQAWSPFQYGMFEGTFIDSPKFKALNDELQKVADHYHTNKNAIAVAWLLRHPVGVQVIL
                     GSMNPEHIKESAEGADITLTRQEWYDIYFAAGNDLP"
     CDS             5001..5234
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_16"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.9e-15,
                     bitscore: 47.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYNYRQLDDFQLSGVSGGKKKFDCAATFVTGITAGIGSGTITGL
                     AGGPFGIIGGAVVGGNLGAVGSAIKCLGDGMQ"
     CDS             5231..5446
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_17"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 8.7e-10,
                     bitscore: 29.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISKEVGITLKQHDLVLIQGGAKRRNKPSGCIVSTIGGAVAGAAG
                     LNPFTTVAGAAIGLSLCLSTNYIHPA"
     CDS             5582..5749
                     /locus_tag="ctg35_18"
                     /transl_table=11
                     /translation="MDKIISIIIVILILLATIAFYLAPFVGGLWQGAARSKVIAKILPQ
                     FTIQVQHPDD"
ORIGIN
        1 gaggtaaaca tgagcaaata tcgaacagaa acggacacat taggaccagt tgaaattccg
       61 gcaaacgctt tgtggggacc gcaaacagag cgcagccggc ataattttca ggctggtcca
      121 ttgatgccga tgccagtgat tagggccttg ctgcaactca aaaaagcggc agcgcgagca
      181 aatgtggccg ctgatgtttt accggcacca aaaggccaat taatcacgcg agcagtcgat
      241 gccttgttgg ccttgccaga cgaaaaactg caaaaagatt ttccactgca tgtttatcaa
      301 accgggtcag gcacacaaac aaatatgaat gtgaacgaag tcattagcca ccaagctgca
      361 aaactcaacc ccgacttgcc gatcttaccg aatgatgatg tgaatcacag ccaaagctcc
      421 aatgatactt ttccaactgt gatgaatatt acggcggcta ttgcagtgaa tcagttgctg
      481 cacgctgtca accaactgtg cagtgtttta tattcaaaag ccgtcactta cgctcgtgtt
      541 gttaaaatcg gtcgaactca tttacaggat gcaacgccgc taacgtttgg ccaagaaatc
      601 agcggatggg tggccatgat ggagcatgat cagattgctt taaagcagct tcagcccaat
      661 cttttttact tagccattgg cggaacagca gtcggaacgg ggcttaacgc tgaccctaat
      721 tttggcaaga ttgtggcggg ccgattgagc gatgtttatc aattaccact ttcggcgaaa
      781 accaataagt ttgctgcttt agcggctcac tcagaaatta gcgttgttca tggtgccgtt
      841 aaaacgctag cggctgatct gcttaaaatc gccaatgaca ttcgcttcct tgccagtggt
      901 ccacgtgctg gatacggcga gttgcgcatt ccggccaatg agcctggtag ttccatcatg
      961 ccgggcaaag tgaatcccac acaggccgaa gcgctaacca tggccgctgt tcgagtcatg
     1021 ggcaacgata cgacgatcac ggtggccgcg tcacaaggca attttgaatt gaacgtctac
     1081 aagccggtta tcatcagtac ctttttagag tcagctgatc tactaaccaa aacagtcacg
     1141 agtttcactg aaaaattagc tgccggcttg accatccacg caccgcatat gagagcactc
     1201 gttgatcatt cgctcatgct ggtcaccgcc ctcgcacccc acatcggcta cgaaaaaagt
     1261 gccgccatcg cgcaattggc tgagcaagaa aacctcgatc taaaagcagc cgccatcaaa
     1321 agcggcgacg tcacagcagc gcagtttgat aaatgggtcg acccgttaaa aatgacaaga
     1381 gcgtgagctg gcgcggttag ctcggcgtag cgaagtggca gtgacacaga tggtctgggc
     1441 tttggaccat ctgtgtcact gttcttcgca tagccgagct gcgctggtga acgcgtttaa
     1501 atcagagcgt gagcaggtga tgatcacacc ttgatttaaa acttataaat cactggtagc
     1561 tccaggcacc atcgcgtaag ttgaagacgg caagaaaaaa gccgagcttt ttacagctcg
     1621 actcgcacga tgatttgaaa tgctagatta atcttgaggc acgttgcttg atgtcataga
     1681 ctgcgcagtt gttaacggga caccttttgc cccaccggaa atactttcga taaaatcgag
     1741 gaaggtcggc gcaatgccaa gttcttcaag atcagcaggg gcgatctggt aacggatcgc
     1801 cttttcgtca tggtctaaga ccttctgaac ccagtgcggc tcgcgaatca tttcgtgacc
     1861 aatggcgacc aagtcaaagg aatctgccgc tttctcagca tcggctggcg ttttcagacc
     1921 accaaccaca atcactggaa aagcaccggc gacgtggtca cgaatttgtt cattcatgat
     1981 ggctgtgtcc tcagggttgc gcaatgaggt tcgccaaacg tcactttggg agacatgcag
     2041 gtaatcaatc ttggtttgtt tcaaagcgtc gattaaggcc aaggtatcat ccaaggtaat
     2101 gccaggctgt tccaactctt ccggcgaaat gcggtagcct aacaaaaatg gccggtcagc
     2161 aattgtggca atcacttttt ctgcttcatg aacgactgcc aacggaaaac gcatccgctt
     2221 atcgcggtca ccgccccatt catcggttcg gcgattagag tttggcgaat agaattgctg
     2281 tatcagacag gtgttggcac catgcagttc gatgccatca aaaccagcaa ggatggcgcg
     2341 gcgcacagcc tgaccaaaat cgtgaatagt ggcctcgatt tctgccgatg tcaatgcgcg
     2401 cggtgtttcg taaccctccc gtggcgcagc aaccgcactg gcactgactg gctgctcacc
     2461 gcgcagaatc ttgctattgc tcatgcggcc agcgctgaag atttgcaaaa tagccttggt
     2521 gccgcctgtt ttcatcgcag cggcgagttt gctcaaaccg gggatgaatc gatcatcagc
     2581 gacacttagc tcaccttcga atcctttgcc aagcgcattg acattggcgg taccggtaat
     2641 aaacatgccg acgccaccgg cccgctgctg gtaatacctg atttcgtccc gcgtcacagt
     2701 gccgtcttca aacgacaggc gcgttgtcat cggcggaatg acaatgcgat ttttcaacgt
     2761 gatggtttgg tgcttgaagg tgaaccgttt taaaaaatga taacccgaca tgcaatcaca
     2821 ctcctttaga cgaaaattaa cgttcttgcg tgactggccg taagagcact tcattgatgg
     2881 caacattggc cggttgatca atggcataca aaactgcctt ggcaacatcc gaggcgctga
     2941 ggccattgtt tttttcatcg gcttcaacag cttcacggcg cttaggatcg gtaattgtgc
     3001 tgaaaagctc agtattcacg gcaccgggcg agatcatggt cgttttaata tgattagccg
     3061 cttgttcttg tcgcaggccg tccatgatcg cctggatagc ccacttggta ccggagtaaa
     3121 cggcggttcc agggtgaaca atgtgaccgg cgaccgagtc tgttgtgata atttggccac
     3181 tgtgttgagc aatcataggc ggtaaaaccg cggcgatccc atacaagacg cctttaatgt
     3241 tgacgtcaat catacgttcc cattcgttga ctttgagttc ggccatttca gaaagtggca
     3301 tcaggccagc gttgttatac aaaacatcca catgaccaaa cttatccaac gccaaatcaa
     3361 tcagcgcttt cacttgctgc tggtcggtca catcggtttg ttgataaagc acctgaccgt
     3421 ccgtaaagct ggccgccaat tcagccaacc gttctgtgcg ccgcgcaccg atgactagtt
     3481 ttgcaccagc ctcggccaac acttgtaccg ttgccgcgcc aatcccgctc gatgcacctg
     3541 tgattacaac cactttatct ttaactgtca aaatcacggc ctccattatg ggcttatcct
     3601 gctaagaaaa aataagtaac agacacagct taacctaccg cgcagctcag caccatgcaa
     3661 gctgttttat tgaaattcta atattggctt gacctcaagt ggactttagg ggctacactt
     3721 aacttgtcgt cagtaacata atttgaaatg acgtatcgaa gggagttttg tgtttatgaa
     3781 acaagttcga ttaggcggat tcaattggca ggcgtcaagt gtggccttgg gcatcatgcg
     3841 gatgaatgtg ctggcccccg acaaagcggc caatgtgctg gatagtgcgt acaatgacgg
     3901 catcaacttt atcgactcgg ccgacattta tggccaaggc aaatccgaag aagtttttgg
     3961 tgaagccttg aagcaagcca gcgtttcccg cgatcagtta ttcattcaat cgaaagtcgg
     4021 gatcgtcgtt gatccaaaac gctctcatgg cagtttggta ttcggcaaac ggtacgactt
     4081 ttcaaaagat cacttactgt cagcggttga tcacattttg aaacggttgc aggttgatta
     4141 ccttgattcg gtcttgctgc atcggccaga tccgttaatg gaagtcgatg acgttgcggc
     4201 ggcctttgat gcattggaac aaagcggcaa ggttcggcat tttggcgtct ccaactttaa
     4261 ccctgaacaa cttgcgttgc ttgaaagcgg cattcggcag cctttgctga tcgaccaagt
     4321 tcagttctcc gttgcgcaca ctggtatggt caatgcgggg atgcacacca acatggccga
     4381 cgcggcttct gtcgatcatg acggcagcct gctaccatac ttgcaacgca aacacatgac
     4441 cttacaagcc tggtcgccat tccaatacgg catgtttgaa ggtaccttca tcgatagccc
     4501 gaagtttaag gcgttgaatg atgaactgca gaaagtcgct gaccactacc ataccaataa
     4561 aaatgcaatc gcagtcgctt ggctattacg ccatccagtc ggtgtgcaag tgattctcgg
     4621 ctctatgaat cctgaacata tcaaggaaag tgcggaaggc gcggacatca cgttgacccg
     4681 acaggaatgg tatgacattt actttgcggc ggggaatgac ttgccgtaag ttgatgatat
     4741 gaaaaaattg tctcaaattg ctgagacgat tttttttgca aaaaattgaa gtttttacca
     4801 agcaaggaga tttaaacgtt aagaattttt gacttttaaa gcgcaactga acaataaaag
     4861 tgtaaagacg acgttaaact ggaaatttcc tacgtttaaa aaattttggc attttacaca
     4921 aataattaat gtatgttaaa gacagtaaag tcgaccttac acaaaatagc ttgttgcttt
     4981 ttgaagaaag aaggaaaatt atgtcttata attatcgcca gcttgacgat tttcagttgt
     5041 caggggtttc aggtgggaaa aagaaatttg attgtgctgc tacatttgtt actggcatca
     5101 cggctggtat tggatcagga acgattactg gcctagctgg tggtcctttt gggataatcg
     5161 gcggcgccgt agttggtgga aacttaggag cggttgggtc agctattaaa tgcttaggag
     5221 atgggatgca atgataagta aagaagtggg cattacttta aaacagcatg atttggtctt
     5281 aatccaagga ggagccaagc gacgcaataa acctagtggg tgtattgtgt ccacgatcgg
     5341 gggagcggta gcaggggcag ctggattaaa tccatttaca actgttgcag gcgctgcaat
     5401 aggattatcc ttgtgtctca gcactaatta cattcaccca gcctaatatt ggacaaagac
     5461 ggttagctcc tatcgcaact gttcaatata actaacacct tggtagtgct cactttttct
     5521 tgtcttagtc aaagatcgat ttcaaattag tctatttgtg caaaaggaag aggaaataca
     5581 aatggataag ataataagta tcatcatagt tatcttgatt ttactggcga cgatcgcttt
     5641 ttatctagca ccatttgttg gaggactttg gcaaggggca gcaagaagca aagtcattgc
     5701 caagatactt ccccagttta caattcaagt gcaacaccct gacgactaga ccataaaggc
     5761 catgaagacc tattcttgtt agtgctagct aaacaagaaa gcaggaa
//
