LOCUS       c00024_JAHCMW0..       16261 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAHCMW010000031.1 Lacticaseibacillus rhamnosus strain Lr-G14
            contig31, whole genome shotgun sequence.
ACCESSION   JAHCMW010000031
VERSION     JAHCMW010000031
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 05:24:30
            Original ID  :: JAHCMW010000031.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1229
            Orig. end    :: 17490
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16261
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6229:14011]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..12782
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..16261
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16261
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             581..913
                     /locus_tag="ctg24_3"
                     /transl_table=11
                     /translation="MNMVQRNQILFILTGLNLSLKKAASGGLMETEAREVVDEALAILK
                     RPNVLKNRAADYALSRLYARFTRLIGLQGMKLSAEANQWWQAVKDFMENDIHGELSQVG
                     GPHFII"
     CDS             1086..2513
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 325.1; E-value:
                     9.2e-99)"
                     /gene_kind="transport"
                     /locus_tag="ctg24_4"
                     /transl_table=11
                     /translation="MSKEEDKELINDGLADDTVIEETDAAITQSQRMSATQVIILGLAL
                     IGAFLGVLDTSIVYTGTVKMAAQLHLNAGALSWVQVAYALTYAGLMLVGGKLGDIYGRK
                     PLFIASLAIFGVGSLAVGAATNALVMISFRAVQGVGAAILAPNCLALLTDTFQGKARQR
                     AIGYYASVIGAGAAVGLVIGGFFATFASWRVGFYMNGPIALIMVGIAARYLPSAKRQTG
                     KIDWIGTILSVLAMTSISYGLDGSPWPIPTLLISAVLWIAFIASQGRVAHPTMPLEIFT
                     DRERMASYVSSLLFSAAAIGFWFYTPQFMQGVLGLTPFMTALGMVPMAILLFIVAVKAR
                     TFVDRWRNSRVMIFGFVTVLLSLAELAVASRFANYWFLLLGTLGFAVGFALAFATLATS
                     GLARIRPEISGAASGVYNTARQFGGALGLAIFAASTASLSKIADVFGQAMLIGVGMTIV
                     GLILVVTLIIPAEKAAK"
     CDS             2568..3008
                     /locus_tag="ctg24_5"
                     /transl_table=11
                     /translation="MAFSVAFSQALEITAYVNAKSQAQHEDYLSIQKISEMLNIPVPSI
                     KKISSTLKKSGILTSKTGLNGGLRLAKTPQTITVYEILAAIEGTAPLFKLHQEIDPAAF
                     VNGERVTSWLVASTNVLNRAEDAMVQVLKQTSIADLAEAAEA"
     CDS             3329..4135
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_6"
                     /sec_met_domain="Abi (E-value: 1.4e-15, bitscore: 48.1,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERKRHLLLSPGFCVLYILLLVVLISQLLLIPAVYMLKLDFWAGN
                     ILFKAIILLVMIALNWLLLKQVIVLKVTLSRPRLKPVIIWGLVLMLIAWFTVTNRTPID
                     VLQAAVIGTIAAVPEEYLFRGVMLGELIRAFYVAHHRHAKYQLLVCIGLSSLVFSLAHL
                     SNLPAQGLVITIAQVIQAFGMGAIFAALYIRYGSLLMPILIHFLIDFVITLVSGPYPKE
                     APSDPNAITMTIVHAFLIAGIYLAIALRLFRRGQNNEKFLARLSHS"
     CDS             4185..4370
                     /locus_tag="ctg24_7"
                     /transl_table=11
                     /translation="MSTRLTKLVDYGLIIATIIFAIYTVTSAFGWTNHGSFVTPMLILM
                     TLLMLLSEREEKQKSA"
     CDS             4756..4941
                     /locus_tag="ctg24_8"
                     /transl_table=11
                     /translation="MTMRTGLALKEISGKMLELTSGGNVPLSNCSVDPPNERHPPAYES
                     AFKYKLPIVHPIKVAT"
     CDS             5001..5186
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_9"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 3.3e-09,
                     bitscore: 27.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHLKTLNTADLASISGGDNGNLWTFIGKAIGSTARSWAEGAMFA
                     PAIGPAKEIVDKLNGN"
     CDS             5655..5813
                     /locus_tag="ctg24_10"
                     /transl_table=11
                     /translation="MTKLNEAELSKISGGIGPLAIPVAAILGFLATDAWNHADELVAGV
                     KQGWERS"
     CDS             5991..6290
                     /locus_tag="ctg24_11"
                     /transl_table=11
                     /translation="MNKLKWFAGGNERAEQAIQLIDELLHDFDDSSFRSDRIRTVLRNN
                     KEALIHKQAAVPFILSRMNLEISNALLQNNILLTKQQSDKFEQLSSLANIRYGY"
     CDS             6324..6413
                     /locus_tag="ctg24_12"
                     /transl_table=11
                     /translation="MVSFTDSFGADQTPIAMLVGMGLLSMDDA"
     CDS             6540..6785
                     /locus_tag="ctg24_13"
                     /transl_table=11
                     /translation="MTILKTMHTWLNEASFWIIVCIFFGGFSLSDSLNKLIVDCLGFDF
                     FIVRAFIEMLSIFIVLILFSKMSVASSRVKDHKRSK"
     CDS             6906..7034
                     /locus_tag="ctg24_14"
                     /transl_table=11
                     /translation="MQYRLFMTANEILGDTTDIWELLLVSESCYPVFYQPKTAKVS"
     CDS             7310..7492
                     /locus_tag="ctg24_15"
                     /transl_table=11
                     /translation="MTVVLYSMLLILAFFFTFVFVTAISWQMIDLLRHRLHARTSFWEK
                     CSQLTQLAISILPFS"
     CDS             complement(7899..8675)
                     /locus_tag="ctg24_16"
                     /transl_table=11
                     /translation="MSKNKTILNIYILEDNPDYLTFIQETVQQYLLIEELPAKIRLATT
                     SATELLATIDWSAINDSIFLLDIELGDSATSGVDVATAIRKKSYYVDILFITSHVDEAL
                     RILEHKIAPLDMINKNSPSKTEKKIRNNILYAIKRLKARQVASPRLFSYSINSSIFSLE
                     MDELIYIQTAPGVSGTLELHAENEITTFPGNLKELATKYTNLCRCHKSILINPAHVLRL
                     DITNRFVYMDNQDKLEVSIRRIGELRNILTGTRALS"
     CDS             complement(8680..9975)
                     /locus_tag="ctg24_17"
                     /transl_table=11
                     /translation="MTLMSDTTYFFITLPIFLTGIYFLTFVFESRSRVIHITFWSVFGT
                     LLSLLLSTYGEVFFFIIYACYVAKTTSRSNVFWVFIFMEVNLIVITAHTTSTQALVLLK
                     ARLDPCILIADSVINLAVFIATIWLLSKKKEQIIKLRDLVREQNKLQRSILIYTGANCA
                     SLYCFEATWNLIDLNNFLSWLSLGVFLLSVVISLYSIFFILKSYKYYIELIWIKRAESS
                     QRAYYATLAQQQKRTDKLLHDYKNLLATLQLSMDQSTHNISSETRDVVSKAQQALSQVE
                     FNQETFDAIKSDSLKSLLYLKWTEALHQNIKMYVHIEGIIEPLDSSTSFAVIRALGILI
                     DNALEETSRSGNSKFSVLLINSSSYLEVNVINDVTAGFELSNLNQSGFTTKGHGRGKGL
                     TIINELIEQNKKISLKKKVKDNQLKITLFVWR"
     CDS             10162..10314
                     /locus_tag="ctg24_18"
                     /transl_table=11
                     /translation="MNNKKEFQRQMKSSVISDDRLTEILGGGRPISSTFNNLRKWLIEQ
                     FQGKH"
     CDS             10590..12782
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 311.7; E-value:
                     1.6e-94)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_19"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1107.2,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 9.5e-42, bitscore:
                     132.5, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKYTPKLGQITYYKRFYTAQVDERDCGVAALNMLLKYNGSDYSL
                     AHLRELAKTNQDGTTALGIVRAAEALAFETKPVQANMQLFDLEDVPYPFIAHVLKRGEL
                     LHYYVVFKATRTSILIGDPDPSVRMTWLSREVFEKEWSGVAIFIAPAPQYQPRKEDKGS
                     LFAFVPMLAKQKGIIANIILAAVLITVISIVGSYFLQSIIDTYIPNAMRTTMGMIASGL
                     LVAYLLQAVLTYGQNFLMAVLGQRLAIDVILGYVRHLYELPMSFFSTRRTGEIVSRFAD
                     ANKIIDALANTIMTLFLDVWIVLILGIVLGIQNGTLFLVSLIAVPCYLVIVFAFQRPFD
                     RLNQETMESNAILSSSIIEDLNGIETIKSLTGERVSYERVDREFLTYLKKSFSYTKADQ
                     LQQAIKGLLKLALNVVVLWIGASLVIANRMSLGQMLTFNALLSYFTNPLESIINLQPKL
                     QMARVANNRLNEVYLVESEFKEQRHLTERHLIEGPIRVRDVSFKYGFGQDVLKNVNLEV
                     PENAKYTIVGMSGSGKSTLAKLLVGFYPVDADKGTITFNGIPVKDINLTTLRQYIEYVP
                     QDPFIFSGTVLENLTLGSRSDVSEQDLTQACLAAEIAADIANLPQQWQTKLSESGSILS
                     GGQKQRLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIA
                     AKTEQIVVMDHGKIVEQGDHATLLAQDGYYARLVHE"
     CDS             12795..14174
                     /locus_tag="ctg24_20"
                     /transl_table=11
                     /translation="MMDPKKLATTEYYQHRFRNFSTMIIMPSTILFLGLLLFLIFARRE
                     VTVLTAAEIEPVKAAVTVQATAANRIVSNRMKEGKRVKKGETLLVYHDVANPTQIKLLK
                     QQLATLKEQQQQLDVLKQSVTENKDLFSKADRFGYQQQVQDYLSQRRVLTLTAEAEQAT
                     QTVASEKNKEIDRLLSASIQTSQAKMAAISEAKAAIQANKPLPSRHAYHYLYQQYESEI
                     KNTDAEAQANLKRQYLAQLQTQLDEEQTNLTSLEQQRAGQKQADVSAQKAGETQANLTA
                     LQSRLQQTAVAEQTKVQQQVQADEAKLATLNDETQNYHVKASASGVLHLETALAGNQYV
                     PSGSVLARILPDLTEQTVADIKLGVSPTEIMSIKRGQKVRLRIAENVPTPTILDGRVYA
                     IDVAPTRDPKVGNFFTVKARVKLSKSQRQSLYYGLAGQASVITGTKTYWDYFADKMFNH
                     R"
     CDS             14235..14645
                     /locus_tag="ctg24_21"
                     /transl_table=11
                     /translation="MTIKNDADQVSQMKGGDRRMDYEEELETKGYIDCLLHELHEQPQL
                     IRQTNIEEVVERTKEEIIRDGFHGYELRRHVFRMILRIDFILTTESVRLSQEGRDAIDE
                     LRRIANGQKKEDPRRFLRIRHFLAQRFQHHMQ"
     CDS             14825..16180
                     /locus_tag="ctg24_22"
                     /transl_table=11
                     /translation="MKAKDNQADRGDQPLSEKHHMQIPWYDVIVSEERQADHATLEERA
                     SLVGRVGIMLLACGTGAWRVREAMNTVARALRMSCSADIGLISLSYTCFSNNHAYSEVL
                     SLPKSGVNTDKLDALERFVRHFDKEYATQTVRDIHHRLDQIQKMSGNYDPLRAGLAAAL
                     ACCAFVFLLGGGPIEMVCCFVGAGIGNWLREIMIRRNWTLLACIGVSVAVACLVYFIAF
                     RGLEMGLGIAARHEAGYIGAMLFVIPGFPFITSMLDISKQDMRSGMERLLYALMITIVA
                     SLVGWLVAMVVHLRPENFVDLGLSPILLLVYRLIASFCGVFGFSVMFNSPRRMAIQAGL
                     IGAVANTLRLELVDLNTIPPAAAAFIGALVAGLIASAINRVDGYPRISLTVPSIVIMVP
                     GLYIYRAVYNIGLNNIGVGAEWMTRAALIIMFLPLGLFTARLIMDSRWRQSD"
ORIGIN
        1 gtccggccgt gaaagctgat gccaaattaa agcaaataat cgaatccaac gcgaaacaac
       61 tggaagatgc agaggacaaa acagcctatg tcgcagtcgt gacccagcta tcgcatgata
      121 tttccaagta ttatctcatt catcacgcga ttccagccga gatgatcgcc attttcaatg
      181 cgatcaaggc ggatgtgccg gcagatcagg tcaatgccaa gcgttatcgc gatcaggcgc
      241 tggctgctgg gctagtcgct tttccaattg tctggggtgg cggacattaa gtagccggat
      301 ggaatatgag cttgttcgat gctgatgaac tgtgtcattt cagccttttt acgactatgc
      361 tgaaatacgc gcttccgatt agtcgtggtt aatgcaccac ggctttttct atgcgctttg
      421 gaccgggcga ttcatgtccg caataacgtt aatcggcgaa aaggctacgt ttatcgaaag
      481 tttgacctga agcttgataa atttggtata ttgcagttag caattcaaga aaacgctatc
      541 tcaatgcaaa cacttatcta ccagacatgg aggagcgctc atgaatatgg tgcaaagaaa
      601 tcagattctg tttattttga ccggattaaa cctgagtctg aaaaaagcgg ctagtggtgg
      661 cctgatggag acagaagcac gggaagttgt ggatgaggcc ttagctattt taaagcggcc
      721 taatgtgctc aagaatcgag ccgcagatta cgccttgtcg cgactatacg cacggtttac
      781 gcgattaatc ggcttgcaag gaatgaaact ttcagcggag gccaatcagt ggtggcaggc
      841 ggtaaaagac tttatggaaa atgacattca tggcgagttg agtcaggtag gcgggccgca
      901 ctttattatt tagacagttg ttgcccaagc catggtctga ttccagtaac cggcccgaat
      961 agaattcgct tgtagccgcg tgtttccata gaattaagga acacgtggtt tttttgctca
     1021 aaaaagattt gccataatag tataaacgga atatactaag tgaaccatag aaaggggcat
     1081 ctcatatgag caaagaagaa gacaaggaat taatcaatga cggcctggct gacgacaccg
     1141 tcattgagga aacagatgcg gcaatcaccc aatcgcagcg catgtcagcg actcaagtca
     1201 ttattttagg gctggcactg attggggctt ttctaggtgt gcttgacaca tcgattgttt
     1261 acacgggtac cgttaaaatg gcggcacaat tgcatttgaa tgctggcgcg ttgtcttggg
     1321 tgcaggtggc ctatgcgcta acttatgctg ggctgatgct agtaggcggt aaattaggcg
     1381 atatttacgg acgcaaacca ttattcattg cgagtttagc tattttcgga gttggcagtc
     1441 tggcagtcgg ggcagctacc aatgcgcttg tcatgattag ctttcgcgct gttcaaggcg
     1501 tgggcgcggc cattcttgca ccgaactgtt tagcattgtt aactgacacc tttcaaggaa
     1561 aagcacggca gcgggcaatt ggctactacg cctctgtgat tggagccggt gcagcggttg
     1621 gtttagtcat tggcggcttc tttgcaacgt ttgcgtcatg gcgggtcggt ttctacatga
     1681 atggtccgat cgcattaatc atggttggta ttgcggctag atatttacct agtgcaaaac
     1741 gccaaaccgg aaagattgac tggattggta cgatcttgtc agtattagcg atgacttcaa
     1801 tctcatatgg gttggatggc agtccatggc caatccccac attactgatt tcagcagttc
     1861 tttggattgc gttcattgct agtcaaggtc gcgttgccca cccgacaatg ccactggaaa
     1921 tctttacgga tagggaacgg atggcttctt atgtcagttc tttgttgttt agtgccgctg
     1981 caatcggctt ttggttctac acacctcagt ttatgcaagg tgtcttagga ttaacgccat
     2041 ttatgactgc gttaggcatg gtgccaatgg ccatcttact cttcattgtg gcagtcaagg
     2101 cccggacctt cgttgatcgg tggcgtaact caagggtcat gatcttcgga tttgtcacgg
     2161 tgctactttc attggctgaa ctggcagtgg catcacggtt tgccaattac tggtttttgt
     2221 tactcggaac actcggattt gcggtaggat tcgcgctggc atttgccaca ctcgctactt
     2281 cgggtttggc tagaattcgg ccggaaattt cgggggctgc atcaggcgtc tacaacactg
     2341 cccgacaatt tggcggcgct ctaggactgg caatttttgc ggcctcgacc gccagcttat
     2401 ctaaaattgc cgatgtattc ggacaggcaa tgttgattgg cgttggcatg accattgttg
     2461 gcttaatact tgtcgtcacg ctcattattc cggcagaaaa agccgccaag taacgatatc
     2521 attggtataa tagaatatac acaatcgcct aatgggaggt atattcgatg gctttttcag
     2581 tcgcattctc gcaagcactt gaaattacgg cttatgtcaa cgcaaagtcc caagcacaac
     2641 acgaagacta tttatcaatt caaaagattt ccgaaatgct aaacattccg gttcctagca
     2701 ttaaaaaaat ttcgtctaca cttaaaaaaa gtggtatttt aacgtcgaaa accggtctca
     2761 atggcggttt gcgattagcc aaaacgccac aaacgattac agtttacgaa atcttagcgg
     2821 ctattgaagg gacggcaccg ttatttaagc tgcatcagga aatcgatcca gctgcgtttg
     2881 tcaacggcga gcgcgtcaca agttggttag tagcaagcac caacgttcta aaccgagccg
     2941 aagatgctat ggtgcaagtg ctaaagcaga cgagcattgc tgatttggct gaagccgcag
     3001 aagcgtaaat atcgaactct aacttttcat cgcctcattc aagactaacg ttggcgcgtt
     3061 ggtattggat gaggcgattt tgcttacggc attttcagga tcgtgcaact gtggggcagt
     3121 cagtaaatgg gaagtaagtg cgtcttcatt ggcctacctt tttggaaatg gagacgatta
     3181 acgtgttgtc aagtttcaaa acacaacgat tatcggcgaa aacccgacgt ttaaaagtta
     3241 atgatccgta acatgcgcag cctcggtata ttgtgggtag cgatatcgaa gctgcgttgc
     3301 attgaaacgt gtgagtgaag gtggataaat ggaaagaaaa cgtcatttgc tattgtcgcc
     3361 aggattttgc gttttatata tcttgctttt ggttgtgcta atcagccagc tgcttttaat
     3421 tccagcagtt tacatgctta aattggactt ctgggctggg aatatcttat ttaaagccat
     3481 cattttactg gtgatgatcg cacttaattg gctgttactg aaacaagtta tcgtcttaaa
     3541 agtgacactt agtcgaccac gattgaagcc agttatcatt tggggactgg tcttgatgct
     3601 tatcgcttgg ttcacggtta caaatcgaac accgattgac gtcttgcaag cagctgtgat
     3661 tggtactatt gccgctgttc ccgaagagta tttgtttcgt ggcgtcatgc ttggcgagtt
     3721 gattcgggcg ttttatgttg cccatcatcg ccacgccaaa taccaactct tagtttgcat
     3781 agggttaagc agtcttgttt tttcattggc tcacctgagt aatttgcctg ctcaagggct
     3841 tgtgataaca attgcccaag tgatccaggc atttggcatg ggggctattt ttgcagcact
     3901 ttatattcgt tacggatcgt tgcttatgcc aatattgatc cactttttga ttgattttgt
     3961 tatcactttg gttagtggac cgtatccgaa agaagcgcct agtgatccca acgctataac
     4021 gatgacgatt gttcacgcat tccttattgc cgggatttac ctagcgattg cactgcgact
     4081 ttttcgccgt ggccaaaaca atgaaaagtt tctggcacga ttgtcgcatt cgtaaactgg
     4141 ctgtatgtat caattatgat agaacgagtt taaggagaaa aacgatgtct acgcgactga
     4201 ctaaactagt cgattatggg ttgataatcg ctaccattat tttcgccatt tatacggtca
     4261 catcggcatt tggatggacc aatcacggca gttttgtgac gccaatgttg attttgatga
     4321 cgttgttaat gctgttaagc gagcgggagg aaaagcagaa gagcgcgtga atcaaaaaag
     4381 attttggcgc tgcttattaa catttattgt cggttatatg tgtgcagttt gtcatcattt
     4441 ccccggcgaa tggatgcaca tgctggccgc gagcctaatc gcctttctaa gttggcttaa
     4501 gactggatgc tcacagtggc gaaaaagaca tgggtaaaag taaatacagt tgcagttgct
     4561 tgagttttga agagaaggcg gcaatatcaa ataatcgccg ggtttttaac gataaacgtc
     4621 aaaattaggt tttttacgac gattttcttg caaaaatcga cgttaaaaaa ttcattccca
     4681 caaacctggc tgtctacttt atattgatgg ggaagaaggg aagtccttct aacaaaggga
     4741 aaggaggaaa atgggatgac catgcgaaca ggactagctt tgaaggaaat ctcgggaaaa
     4801 atgcttgaat tgacgagcgg tgggaatgtt cctttatcca attgcagtgt ggatccacca
     4861 aacgaacgcc atccgccagc ttacgaatcg gcatttaagt ataaactgcc gattgttcat
     4921 ccaattaagg tggcgactta agtgataatt taggctgata gatagattga aaggctcata
     4981 aaggaaaaag gaggaagaac atggatcatt taaaaacttt aaacacggct gatttggcaa
     5041 gtatttctgg tggcgataat ggtaatctgt ggacctttat cgggaaggcc attggttcaa
     5101 ccgcgcgttc ttgggctgaa ggcgccatgt ttgcaccagc cattggtcct gccaaagaga
     5161 ttgttgataa acttaacggc aattagtatc cgggatgaat aggcactcga acgggcgaac
     5221 gtatgaataa gataaatctt ttaatgttag ctacgtttat cttggtatat ctattaggtg
     5281 ttttggtata tacgtgctgt aaaaaagatg gtcactatcg cgtttggaat gataaatatc
     5341 tcgacagtga gcatcagata gcctttaaac gtgcttatat tttgaatgcc atctggttta
     5401 ttacctacgc ttaaactttg agtgttccgt tcaatgccta ggccgtacgc tgtaatgctg
     5461 ccatacaaac caagtggcag aatttcgatg gtgaaggtca agtggcttta atccaggcat
     5521 gccgctgatg actccatggt tgtatttgca aaaagttgtg cggtagatga gcattttatc
     5581 gccacaatat ccataacaaa gacttttgga tcaactggcg agtagtttct tacaaataca
     5641 aggaggtaat tttaatgact aagttgaatg aagctgaatt gagtaagatt tccggcggta
     5701 tcggaccgct cgcaatccct gtcgctgcta ttcttggatt cctggcaaca gatgcgtgga
     5761 accatgctga tgagctggta gctggggtca agcaaggatg ggaacgatcg taataacggt
     5821 gcgttgattt ttagcgattt cgccgttgta aaagtatctc ttcccagaac aagtttttat
     5881 ctgtgggcga gcatgcactt accgttattg ctacggcaga tctggcaatg cacggtgcca
     5941 aacgtgttac aagtgaagat gcacaagcac aacgtttttt ggagtgaatg atgaacaaat
     6001 tgaaatggtt tgctggcggg aatgaacggg ctgaacaagc gatacagctt atcgatgagc
     6061 tgcttcacga tttcgatgac agttctttcc gtagtgatcg catacggaca gtgttaagga
     6121 acaataaaga agccttaatt cataagcaag cagcggttcc atttatttta agccgtatga
     6181 atctagaaat ctctaatgcc ctgttgcaaa acaatatttt gttaaccaag caacaatctg
     6241 ataaattcga gcagctttct tcgctggcga atatcagata tgggtactag aagccactac
     6301 taaaacggtg agcgcgcttg attatggtta gcttcactga ttcatttggt gcagatcaaa
     6361 ctccgattgc gatgctggtt ggtatgggct tgttgtcaat ggatgatgcc taaaaggttg
     6421 tccaatttat aacggcgact taggcaaact agtttcgaat ataacggtct aacttaaaaa
     6481 gacagagcca aaactgatcg gtcgataaat gatttagtga tgagcaaagc ggaggtacga
     6541 tgacgattct taaaactatg cacacatggc ttaatgaagc ttctttctgg attatcgtat
     6601 gtatcttttt cggcgggttt tcgctcagtg atagcttaaa caagctgatt gtcgattgct
     6661 tgggttttga ttttttcatc gtccgggcgt tcattgagat gctttcaatc ttcattgttt
     6721 tgattctttt ttctaaaatg agtgtcgcat cttcaagggt taaagatcat aaacgctcta
     6781 aataacaaat tttctttgtt tgatttcgaa gtattggtaa ggcggcagcg tcattgtcag
     6841 tgggaagcct gtcagcaccg agagacagca actattgtga cacagctatc tgccaggcca
     6901 taataatgca atatcggctg ttcatgacgg caaatgagat tttaggggac actactgata
     6961 tttgggaact gcttttagtg tcagaatctt gttaccctgt gttctatcag ccaaaaaccg
     7021 caaaagtctc ctgatttgta ttgaaacaaa aatacaaatc aggagatctt gcgcgtgagt
     7081 atggcagaac agatactaaa taagatgagc tttcaaaacc cacgattgtt ttttcttcct
     7141 gacagcaaaa ggcctttcgg aaatagcatt aaatagctaa aatggtgtca tttttgtgat
     7201 ttcttgcttg tatgaccgac cttagcagaa cgtatggtat ctccgaacct gtgctcgcta
     7261 atttgccgcc tcaatgtaag tttaaaggaa gactcaagga gctttgctta tgacagttgt
     7321 gttatattct atgcttttga ttctggcatt tttcttcaca ttcgtatttg taactgcgat
     7381 cagctggcag atgatagacc tcttaagaca tcggcttcat gcgcgaacat ctttttggga
     7441 gaaatgttcc caattgacgc agttggccat tagtatattg cctttttctt agaaggtggg
     7501 agaacataaa gaacatgtta ctaatggatt gctgaaagaa gtaaaaataa gtctgtttgt
     7561 aaacgaggtg agcgtaatcg atcaatttgc aagattatca ttccaacaga aagtgtcgtt
     7621 gcttgtcgcc attggggttt taataatggc gttttggtac ttttcaccgg gaattttaaa
     7681 agggatatat gacgctggtt atcgaatggg tcagtcgata gcgctttggt tgaagtagaa
     7741 ccgatgacag attggcataa aacctttcag gaggaatagt atttccaacc tgtataaacc
     7801 aaccaaataa cgcacccttg atattgagga tgcgttattt gtgcgttcag ctgtgttgat
     7861 taacagaaat ctaggatgat tgcccagtca cactcttctt aagataaagc ccgtgtgcct
     7921 gttaagatgt tgcgcaactc gcctattctc cgaatactga cctcaagttt atcttgattg
     7981 tccatataaa cgaatcggtt tgtgatgtcc agacgcaaaa catgtgcggg attaatcagg
     8041 atactcttat ggcatcgaca taagttggta tatttggtcg ctagttcctt aaggttgccg
     8101 ggaaaggttg tgatttcatt ttctgcatga agctccagtg tccctgagac gccgggagca
     8161 gtttgaatat agatgagctc atccatttca agtgaaaaaa tactggagtt gatgctgtag
     8221 ctaaataatc tgggagatgc gacctgacgc gcctttagac gttttattgc ataaagaatg
     8281 ttatttcgaa ttttcttttc tgtctttgaa ggtgagttct tgttgatcat gtccagaggt
     8341 gcgattttgt gctctaaaat ccttaaagct tcatctacat ggctagtgat gaagaggata
     8401 tcgacataat atgacttttt ccgaatggct gtggctacat ctacgccgct tgtcgctgaa
     8461 tctcccagct cgatatcaag gaggaagata ctatcgttga tggctgacca atcaatagtt
     8521 gcgagcagtt cggttgctga cgttgttgcc agccggatct tggcgggtag ttcttcaatc
     8581 agaaggtact gctgcacagt ttcttggata aaggttagat agtcagggtt gtcttcgaga
     8641 atataaatgt ttaggatcgt tttgttttta gacataaagt tacctccata caaaaagtgt
     8701 gattttcaac tggttatctt tgaccttttt cttaaggctg atttttttgt tttgttcaat
     8761 cagctcgtta ataatggtca acccctttcc gcgaccatgg cctttggtgg taaatccaga
     8821 ctggttaaga tttgatagtt caaatcccgc ggtcacgtca ttgatgacat taacttccag
     8881 gtacgagctt gaattgatta ataagacact aaactttgag tttccggagc ggcttgtttc
     8941 ttctaaagcg ttgtcaatta aaataccgag tgcacgaatg accgcgaatg aagtgctgct
     9001 atcgagcggt tcaatgatcc cttcgatgtg aacgtacatc ttgatattct gatgtagcgc
     9061 ttctgtccat tttaaataga gtagactttt caacgaatcg cttttaattg catcgaaggt
     9121 ttcttgattg aactcgactt gagatagcgc ttgttgtgcc tttgaaacaa cgtctcgcgt
     9181 ctcagaagaa atgttgtgag ttgattgatc cattgacaac tgcaacgtgg ctaataagtt
     9241 tttgtaatca tgaaggagct tgtccgttct cttttgttgc tgtgctaacg ttgcatagta
     9301 agcacgctgg gaactttctg cccgtttaat ccagatgagc tctatataat atttatagga
     9361 ttttaagata aagaaaattg aataaaggct gatcacaact gaaagtagga atacgccaag
     9421 gcttaaccag gacaagaaat tattgaggtc aatcagattc caagtagctt caaaacaata
     9481 gagtgacgca cagtttgcgc ctgtgtaaat aagaatggaa cgttgcaatt tattctgttc
     9541 tcgaactaag tcgcgcaact ttataatttg ttctttcttc ttagatagta accagatagt
     9601 cgcgatgaat actgctaagt taataactga gtcggcgatt aaaatgcaag gatcaaggcg
     9661 tgctttgagc aagaccaaag cctgtgtact agtagtgtga gctgtgatga cgatcagatt
     9721 gacttccata aagataaaaa cccagaaaac atttgaacgt gaagtggtct tagctacata
     9781 acacgcatag atgataaaaa agaagacttc gccataagtc gaaaggagca aagacagaag
     9841 cgttccgaag actgaccaaa aagtaatgtg gataactctg gaacggcttt cgaaaacgaa
     9901 ggtaagaaag taaattccag tcaaaaaaat aggaagggtt ataaagaagt aggttgtgtc
     9961 tgacatcagt gtcatataga aaacctccgc tagttatgaa agtatggcaa gttcttcata
    10021 ccgaatgaaa ataaatgacg tcatatgcta acgatataac gttaaatggc caaaacacga
    10081 cgtttatttt ttgtaggccc taaaaagctc acgacatgtt aggttaaata cagaagaata
    10141 aatcgtagga ggtaggttga aatgaacaac aaaaaggagt ttcagcgtca gatgaaaagc
    10201 agcgtaattt cggatgatcg tcttacggag atacttggtg gtggccgacc aataagctca
    10261 acatttaata atttgagaaa gtggctcata gaacagtttc aggggaagca ttaaaggcca
    10321 gacagacgat tgccttcaac gtataaaaat aaatatttag atatataaaa gtgcttttaa
    10381 ttttaatatt tatttttata cgctattaat cctgctctaa aatatactac cacacatttt
    10441 aaatgtaaaa aactaaatct tacagtgctt atatcaaaag ggtaacccca aatttgggga
    10501 ttcactacct gtatttttga ctaaacgtca tggtatatcg gctcataaaa gaggcctgaa
    10561 tctaatggct taataagcga ggagagttaa tggttaaata caccccaaaa ctaggccaga
    10621 tcacctacta caaacgtttc tacaccgcac aagttgacga gcgtgactgt ggtgtggctg
    10681 cgttaaacat gctgcttaaa tacaatgggt cggactattc gttagcccac ttgcgcgagt
    10741 tagcgaagac aaatcaggat ggcacgacgg ctttgggaat cgttcgggcc gctgaagcac
    10801 tagcgtttga gacgaaaccg gtgcaggcga atatgcagtt gtttgatctt gaggatgtgc
    10861 cttatccgtt tattgcccat gtgctgaagc gcggtgaatt gcttcattac tatgttgttt
    10921 ttaaagcaac gcgcacgagt attctgattg gcgatcctga cccgtcagtg cgcatgacct
    10981 ggctttcgcg agaggtgttt gaaaaagaat ggtcgggtgt ggccatcttt attgcaccgg
    11041 cgccgcagta tcagccgcgt aaggaggaca aaggcagttt gtttgcgttt gtacccatgc
    11101 tggctaagca aaaaggtatt atcgcgaaca ttattctggc cgcggtattg attacggtca
    11161 ttagtatcgt tgggtcgtat tttttgcagt ctattattga tacgtatata ccgaatgcca
    11221 tgcggacgac gatggggatg attgctagtg gccttttggt ggcttacttg ctgcaagctg
    11281 tgttgactta tggccagaat tttttgatgg cggtgttggg gcagcggctt gcgattgatg
    11341 tcattttagg gtatgtgcgc cacttatatg aattgccgat gtcgtttttt tcaactcggc
    11401 ggaccggaga gattgtgtcg cggtttgcgg atgccaataa aattattgac gcgctggcga
    11461 atacgattat gacgttgttt ttggatgtct ggattgtcct aatattaggc attgttctag
    11521 ggatccaaaa tgggactttg tttttagtgt cattgattgc cgtgccgtgt tatttggtga
    11581 ttgtttttgc atttcagcgg ccgtttgatc ggttgaacca agagacgatg gaaagtaacg
    11641 caatcttgag ttcatcgatt attgaagatt tgaatggcat tgaaaccatc aagtccctga
    11701 ccggcgaacg agttagctat gaacgggttg atcgggaatt tctaacctat ctgaagaaat
    11761 cgtttagtta caccaaggca gatcaattac agcaagcgat taaaggtctg ttgaagctgg
    11821 cgttgaacgt tgtggtgttg tggattgggg caagtttggt gattgccaat cggatgagct
    11881 tggggcagat gctgaccttt aatgcactgc tgtcatactt tacgaatccg cttgaaagca
    11941 tcatcaacct acagccaaag ttacaaatgg cgcgggttgc taacaatcgc ctgaatgaag
    12001 tttatctggt cgaatcggaa ttcaaagaac agcggcactt gacggagcgg catttaatcg
    12061 aaggtccgat acgcgttcgg gatgtctcgt ttaaatatgg ttttggccaa gatgtattga
    12121 aaaacgtcaa ccttgaagtg ccggaaaatg ctaaatatac cattgttggc atgagcggtt
    12181 ctggtaagtc gacattagca aaattattag ttggctttta cccggttgat gccgataaag
    12241 gaaccatcac gtttaatggc attccggtca aagacattaa cctgacaaca ttacggcaat
    12301 atattgaata tgtacctcag gatccgttta ttttttcggg cacggtgttg gagaatttga
    12361 cgttaggtag ccgttcggat gtttcggaac aagatttgac gcaggcgtgt ttggctgcgg
    12421 aaattgccgc agacatcgca aacttaccgc agcagtggca gaccaaattg tcagaaagcg
    12481 gcagtatttt atcaggcggt cagaagcagc ggctggcgat tgcacgggcc ttgttgtcac
    12541 cggcaaaagt actgattttt gacgaatcga ccagcagtct ggataccatt acagagcgaa
    12601 aaattgtcga tcgcttgctg gcaatgacgg atcggaccat tatttttgtt gcccatcgct
    12661 taactattgc ggctaaaacc gaacaaattg tggtgatgga tcatggcaaa attgtggaac
    12721 aaggtgacca tgcaacgttg ttagcccaag acggttatta cgcgcgcctg gttcatgagt
    12781 gaggtgagct ttagatgatg gatcccaaaa aacttgcaac gaccgaatat taccagcacc
    12841 gctttcgcaa tttttcaacg atgattatta tgcctagtac gattcttttc ttaggcttgc
    12901 tattgtttct gatctttgct cggcgcgagg taactgtgct gacagctgcc gaaattgaac
    12961 cggtaaaggc agccgtgaca gttcaggcga cggccgccaa tcggatcgtc tcgaaccgca
    13021 tgaaagaagg caagcgcgtg aagaaaggcg agaccttact tgtttaccac gatgtcgcta
    13081 atccaacaca aattaaatta ctcaagcagc aactggcaac gctaaaagag caacagcagc
    13141 aattggatgt tttgaaacaa agtgttaccg aaaacaaaga tcttttttca aaggcagacc
    13201 gattcggcta tcaacaacag gtgcaagatt atctgagtca acggcgagtg ctgacactga
    13261 cagcagaggc tgagcaggca acccaaaccg tcgctagtga aaaaaacaaa gagattgatc
    13321 ggttactaag cgccagtatc caaacgagcc aagcaaaaat ggccgctatc tccgaggcaa
    13381 aagcggcgat tcaggcgaac aaacccttgc ccagtcgcca cgcctatcac tacctttatc
    13441 aacaatatga aagtgagata aaaaataccg acgcggaggc acaggcgaac cttaaacgcc
    13501 agtaccttgc tcaattacag acacagttgg atgaggaaca aaccaatttg acgtctttag
    13561 agcagcaacg ggccggtcaa aaacaagcag atgtatcggc tcaaaaagcg ggagagactc
    13621 aggctaatct aaccgcatta caaagtcggt tgcagcaaac agccgttgcg gaacagacga
    13681 aggttcagca acaggtccaa gcagacgagg ctaagttagc taccttgaat gatgaaactc
    13741 aaaactatca tgtcaaagca agtgccagtg gcgttttgca tttagaaact gccttggccg
    13801 ggaatcaata cgtcccttca ggaagcgtgt tggcacgaat tctgccggat ttaacggaac
    13861 aaacggttgc tgacataaaa ttaggcgttt cgccgacaga gatcatgagc atcaagcgtg
    13921 ggcagaaagt acgcctgcga attgctgaga atgtgccgac ccctaccata ttagatggcc
    13981 gggtttatgc gattgacgtc gccccaacac gcgatccgaa agttggtaac ttctttacgg
    14041 tcaaggcgcg ggtgaaatta tctaaatcgc agcggcagtc cctttattat ggattagccg
    14101 gccaagcatc tgttatcacc ggcacaaaga cttattggga ttactttgca gataagatgt
    14161 ttaaccatcg ataaatcggt atttaccgct tttgttgttt agtagcgaaa aggcgatgcc
    14221 cattatttaa gaaaatgacc ataaaaaacg atgcggatca agttagtcaa atgaaaggcg
    14281 gtgatcggcg tatggattac gaggaagaat tagaaacaaa aggctatatc gactgcctgt
    14341 tgcatgaatt acatgaacaa ccgcagctca tccgccaaac gaatattgaa gaagttgtgg
    14401 aaagaaccaa ggaagagatt atccgcgatg gttttcatgg ctatgaatta cgacggcatg
    14461 tttttcggat gatactaaga attgatttta tcctcacgac tgaaagtgta cggttgagtc
    14521 aagaaggacg agatgcaatt gacgaactac gaaggattgc taatggacag aagaaggaag
    14581 atcctcgtcg ctttttgcga atccggcatt ttctggcgca gcgattccaa catcatatgc
    14641 aataagttga gaccgagaaa tgattgctag tttgtgcgtg cttgtcatga ataaggcgtt
    14701 caaattcatt agtttcaaaa agtcaaaaat acaccctgtt atgaattgtg ctagaatagt
    14761 gaatgtttat tttcaatttt tttgaaaaag acaatcccta taagaagaag gattagcacg
    14821 agttatgaag gcaaaagata accaagcgga tcggggagac cagccgcttt cagaaaaaca
    14881 tcatatgcag attccgtggt atgacgtgat tgtcagcgaa gagcggcaag ccgatcatgc
    14941 cacccttgaa gagcgcgcgt cactcgttgg ccgagtcggg atcatgttgc tggcgtgtgg
    15001 taccggggcg tggcgcgtgc gtgaggcgat gaacaccgtt gctcgagcat tgcggatgtc
    15061 gtgctcagca gatattggct taatttcctt atcgtatacc tgctttagca ataaccatgc
    15121 ctattctgag gtgctttcac tgccaaaaag cggtgtgaat actgacaagt tggatgcgtt
    15181 ggaacgtttt gtgcgtcatt ttgacaaaga gtatgcgact caaaccgtgc gggatattca
    15241 tcatcgactt gatcagattc aaaagatgtc tggcaattac gatccgttgc gcgccggatt
    15301 agcagctgct ttggcgtgtt gcgctttcgt ctttttgtta ggcggcggtc ctatcgaaat
    15361 ggtttgttgt tttgttggtg cagggatcgg taattggctg cgtgaaatca tgattcggcg
    15421 taactggaca ctgctggctt gtatcggtgt cagtgtggcg gttgcctgct tggtttattt
    15481 tatcgctttt cgcggactgg aaatgggact gggcattgcg gcgcggcatg aagcggggta
    15541 tatcggcgcc atgttgtttg tgattccggg cttcccattt atcaccagta tgctggatat
    15601 ttcgaagcag gatatgcgct cgggaatgga acgactactg tatgcgttga tgattaccat
    15661 tgtggcttcg ctggttggtt ggctggtcgc aatggttgtc catttacgcc cggaaaactt
    15721 tgtcgactta ggcctgagtc cgatccttct tttggtttat cgcctcattg ccagcttttg
    15781 tggggtcttt ggattctcgg tgatgtttaa cagcccccgc cgaatggcaa tccaggccgg
    15841 gttgattggg gcagtggcga atacgttgcg gcttgaattg gtggatctca atacgattcc
    15901 ccctgctgcg gcggcattta tcggcgcgtt ggtagccgga ctgattgcgt cggcgattaa
    15961 tcgcgttgat ggctatccgc ggatttcgct aacagtgcca tcaatcgtca tcatggtgcc
    16021 tggcttgtat atttaccggg cagtttacaa tattggattg aataatattg gcgtcggtgc
    16081 cgaatggatg acgcgtgccg cacttatcat tatgttttta ccgctgggct tgtttaccgc
    16141 tcgcttgatt atggattctc gctggcggca aagcgattga tcagtataac tttttagcaa
    16201 cacaaataac cccacttcaa aatgaagtgc cccataattg ttagacagat actctaatga
    16261 t
//
