LOCUS       c00044_JAHFZW0..       21800 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAHFZW010000004.1 Bacillus subtilis strain DS3_4
            NODE_4_length_210492_cov_34.917752, whole genome shotgun sequence.
ACCESSION   JAHFZW010000004
VERSION     JAHFZW010000004
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-19 16:12:59
            Original ID  :: JAHFZW010000004.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 21800
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21800
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8846:11800]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8847..11800
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21800
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /kind="interleaved"
                     /product="sactipeptide"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..21800
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="sactipeptide"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /tool="antismash"
     protocluster    1..20313
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9080:10313](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      9081..10313
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="2"
     CDS             2..67
                     /locus_tag="ctg44_1"
                     /transl_table=11
                     /translation="SLKLVEVKPTIFRIQENENIA"
     CDS             303..1820
                     /locus_tag="ctg44_2"
                     /transl_table=11
                     /translation="MLVSLSLSSLLTLFFIMLMASGISGLLFLHPRVPLSFVRIHIGIL
                     ALPLLVSLLILANSGVSGNVGPWHLDSLACLMTFFVLAIGFIIQRFSVRYLMGDRSYRK
                     YFTLFTFTTGAASMTWLSGDLRLMVLFWGATLVGLTLLIRLNSAWQVASEAAKISGRLF
                     LLSWFSLFFAMMWLFHATGQWQLSLVVTNESLAGLGEWERTGIQLLIVLAVIIPAGQWP
                     FQRWLVESIVAPTPVSAIMHAGLVNAGGIILTRFSPLFHGGIASIILLLLAGISVLIGT
                     GISLVQVDYKRQLVGSTIGQMGFMLIQCALGAYIAAIIHLILHGLFKATLFLQAGSAVG
                     RHEVSARTNERTSYLWVMAGRILSLVIGVAFWLTAPGDGYHLISALILGWSLSVSWTQL
                     VAFGEGRIGRIAGLTVLGGAALVYFIIHHLFYKWLHTTIFQSVQPPMSAVMIVVCLLLF
                     GSALGTWVARHRSSVFFAVLYLWLVRLGEAKPKSVESHPDYLKQYIS"
     CDS             1835..4450
                     /locus_tag="ctg44_3"
                     /transl_table=11
                     /translation="MGITSVLTKDNVNKIDTDIDVQERDLNVFITSASRVIAPLWPIST
                     FAARNPWMGLENQPFDQVASWLKNTRDVDIYPSASMIRSAKNKGEIDEDFVEMGLQRWL
                     DSHSYHIPRDVAERFCHAALKLDPLPSDLLSSHELEKLVSECSGLDHIENVFMQPLSSY
                     IENQDGERLVNILDHHVIKWSKLYLDDSQAGWTMPNREEGFYRAWQHLIQYDPALSKKQ
                     RERVKGWPKEAHLALQEALFALEIPESEIQTYLEGHLLSLPGWAGMMLWRSQQSSHEHA
                     LLTEYLAVRISMEWALIKPYLPLTNERSKKTISIAPLIAAWIHWGGLTLEEWSQMTAIE
                     QNEYLSFAYSFDEKLRKKLWLEAWEQTYTDRLSQKIISKQCETGGKKSALAQLAFCIDV
                     RSEPFRRQLEKEGPFETIGIAGFFGVPIATCELGSKHSHASLPIIQKPQNKIKEFADED
                     VFKKYNQRKQAIHSLSHTFKTMKQNALSSLLLPELSGPWLTLQMAARSFVPRKAGRFIR
                     NLREAWLRKPDTKLSLHHDATEAEMPVGFTDEEKVNYARQALKMMGLTENIAPLVVICG
                     HGSQSTNNPYSAALDCGACGGAAGGFNARVLAALCNLSEVREALLAEGIQIPEDTVFAA
                     AEHNTTVDELHWLYVPELSEAAQEAFEQIEAVMPKVRHHVNAERLAQLPNFQSKLKNPK
                     AEANRFAEDWSEIRPEWGLARNAAFIIGKRELTQDCDLEGRAFLHNYDWKQDESGELLA
                     NIIAGPGTVAQWINLQYYASTVAPHYYGSGNKATQTVTAGLGVMQGNASDLLAGLPWQS
                     VMESDHEAYHSPLRLLILIQAPREYVERLLNNDSAFLQKVQNGWVRLASLDPEGCWESW
                     "
     CDS             4527..5054
                     /locus_tag="ctg44_4"
                     /transl_table=11
                     /translation="MNVNQNKKVLFLTDIENGLEPILQEATNTSAENMLTIQSYGASIS
                     HPYGEIMRSVIFAIYQEDVEEIFVVGTKDKKTFAGNGLTQLETMKDKIQTLDYLFQNCK
                     PEFLGGTVDEWLNENSSDTIEKSVDMIRHHPLVPSHVKVRGLLVNHKDGKPSIMEGPDA
                     KTGQAIPDHCLS"
     CDS             5011..5121
                     /locus_tag="ctg44_5"
                     /transl_table=11
                     /translation="MLKQVKPYLIIACHDEMQVQLLNAPIYGESSSKEIV"
     CDS             5118..5408
                     /locus_tag="ctg44_6"
                     /transl_table=11
                     /translation="MSANLTDFVTKTIEDMNSFDRENMECMKKLIRKAIDFYHLKSYEE
                     VEKTHSGNVRFLHVHSMMEENMLSKMIVVTRNGKTDLDIEGVYEGYVVREY"
     CDS             5465..5839
                     /locus_tag="ctg44_7"
                     /transl_table=11
                     /translation="MKKSKGSIESEISKSITQWEKDYLGRGSVSVKTDILRDMIIVNLK
                     GILTPAEYVVCGSKEGMLSIKQTRSELVESGIEGLKDIILKITGEKVKSFHTDLSSRTG
                     ERVMVFKLCNDLEKNLEKIL"
     CDS             6324..6626
                     /gene_functions="regulatory (smcogs) SMCOG1058:ArsR family
                     transcriptional regulator (Score: 67.7; E-value: 1.1e-20)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg44_8"
                     /transl_table=11
                     /translation="MEPIEVFKALSNESRLQILQWLKEPDRHFAPHEGIDMNTIGVCVS
                     QITDKLKMTQSTASQYLTILLRAGLIKAERIGKYTYYKRDEEAIGKLADFLKTEI"
     CDS             6753..7925
                     /gene_functions="transport (smcogs) SMCOG1184:major
                     facilitator transporter (Score: 336.1; E-value: 3.4e-102)"
                     /gene_kind="transport"
                     /locus_tag="ctg44_9"
                     /transl_table=11
                     /translation="MSNTWKIYILAIVSFLVGTSEYIISGILDQIAHTLGITLAAAGQL
                     ITIFSLVYALSTPVLMALTASMDRRKLMMYALGLFVFGNVLAFVLPGYGWFIAARIIMA
                     MGAGVVVVTALTIAAKIASEGKQGSAIATVVMGFTASLIIGVPLGRMIAVALGWKSVFG
                     AIALLGLIAMVVIFFTLPHTEGDKPVPLLQQLALFKKRKVAMGLSITFFWLGGYSVAYT
                     YLSPYLLNISGINSKLLSGVLLIFGIASLVGSKFGGYSTDKWGVSFTLVGGMTLHIVTL
                     ILLSLVTHSYIGVLVILILWSFAAWSTGPTQQFHLATIEPEMSGVLLSMNQSMMQFAMA
                     VGAGIGGVFVENVSLASITWVGALGVMIAIIASLLIFNSQPKQALKDINQ"
     CDS             8847..9014
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: TIGR04404"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_10"
                     /sec_met_domain="TIGR04404 (E-value: 2e-38, bitscore:
                     123.7, seeds: 3, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRNQKEWESVSKKGLMKPGGTSIVKAAGCMGCWASKSIAMTRVC
                     ALPHPAMRAI"
     CDS             9081..10313
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_11"
                     /sec_met_domain="PF04055 (E-value: 1.2e-22, bitscore: 74.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.1e-07, bitscore: 24.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.2e-06, bitscore: 21.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     1.1e-15, bitscore: 51.4, seeds: 13, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYDRVKDFDLPELAVHLQPHGAVMIDRKSMFYFRLSGRGAQLAF
                     LLSKNKNLHKTARIWEIMKKEEMSADQLKEELSAHPFTEAWTEGLLDQPLHVSGSLDSY
                     LPISCTLQLTNACNLSCSFCYASSGKPYPEELSSEQWILVMQKLAAHGVADITLTGGEA
                     KLIKGFKELVVVASSLFTNVNVFSNGLNWRDEEVELLSHLGNVSVQISIDGMDNTHDQL
                     RGRKGGFKESMNTIKKLSEANIPVIVAMTINESNADEVSDVVEQCANAGAFIFRAGKTL
                     SVGRATEGFKALDIDFEEMVQIQLREARHKWGDRLNIIDWEHEESSFTTDFCTPGYLAW
                     YIRADGYVTPCQLEDLPLGHILEDSMADIGSPARLLQLKCEAKNCKCIGKIELSEPDLP
                     FQKEVKAGIQE"
     CDS             10310..11800
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: skfc"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_12"
                     /sec_met_domain="skfc (E-value: 8.4e-290, bitscore: 955.3,
                     seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="Abi (E-value: 4.1e-14, bitscore: 46.4,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSLSLVFWSILAVVGLLLFIKFKPPTIASLLLSKDEAKEISIQF
                     IKEFVGIDVENWDFYSVYWYDHDTVNKLHHLGILKKNRKVLYDVGLVESWRVRFVHQNQ
                     SFVVGVNANREITFFYADVPKKTLSGKFEQVSPETLKQRLMASPDGLWSRANMTGTGKK
                     EEDFREVSTYWYIAEAGDIRLKVTVELQGGRISYIGTEQEILTDQMSKVIRDEQVESTF
                     GVSGMLGSALAMILAILILVFMDVQTSIIFSLVLGLLIIICQSLTLKEDIQLTIVNAYD
                     ARMSVKTVSLLGILSTLLTGLLTGFVVFICSLAGNALAGDFGWKTFEQPIVQIFYGIGA
                     GLISLGVTSLLFNLLEKKQYLRISPELSNRTVFLSGFTFRQGLNMSIQSSIGEEVIYRL
                     LMIPVIWWMSGNILISIIVSSFLWAVMHQVTGYDPRWIRWLHLFIFGCFLGVLFIKFGF
                     ICVLVAHFIHNLVLVCMPLWQFKLQKHMHHDQPKHTSL"
     CDS             11819..12538
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 178.6; E-value:
                     2.5e-54)"
                     /gene_kind="transport"
                     /locus_tag="ctg44_13"
                     /transl_table=11
                     /translation="MQLMQVQNLSKCYRNGDGVEHLSFSIQRGEIVALLGPNGAGKTTT
                     IRCLTGLYKPDKGDILIEGSPPGDINVQKKVALIPDQPYLYPALTAAEHIQFRARGYHP
                     GKKDVKERVYHALKEVHLEEKANQLCGQLSRGQKQRVVLAGAIVQDALLYILDEPTVGL
                     DIPSKQWLSNWLKTKTDQGCSAFVSTHSLEFVIETADRVILIRDGKLMQDLYVPQFEEQ
                     AEWRKEVIRLLGEWSDE"
     CDS             12603..13946
                     /locus_tag="ctg44_14"
                     /transl_table=11
                     /translation="MPFLIMLLFVGAIGFQVSFVSRSTTWDMSIAGWVLTGVFILYTAF
                     GLFSNRLPSQMADIIWLYGTATSFSKVVYSVLFFSVTWKALLWIISAIFGDVLIVLLSG
                     DHINLLGRSIIFVGLFFIAEVWLMSVSCARTVKKMKRVYVLVFLLMLGIYSICLYRFFF
                     LQHSSGIWESIARFISGVGLVFDTLSPLYVVVFIGIITVSFMTIAFTSRQVEMKESLVK
                     EAEFWEEFQERQFGSGQIIQKPKTTWWGLQGLNGIWSFLWLELLLFKKYLFFHSIHTVM
                     LSGVFYVVIFMYPEWFYLLFFLIVSAVMLSSYYSGIVRHSQSGTLHLFPGALWKKIIIL
                     ELTNTVWLYILYCVSITFMAVGNLVYWYIYGLGIYIWFMTIRLFAFTHTNRNDIKLSLP
                     QYYKSFFMALGLSGICLYVIHLLTADWYTLVVVVCIGSLSWCLFYRFR"
     CDS             13993..14508
                     /locus_tag="ctg44_15"
                     /transl_table=11
                     /translation="MNSNGDKLSLSVQNLANTNEITIVQAIGELKKSGKDAIPVLVEAL
                     KEEGSLCNIAAAVLGEFGEDASEAAEELSCLLKSHAEDTRMAAAISLMRIGKPSLPFVI
                     KIAQESEGQSCFWASWCIAWIDPSCIEPKMYKCLKYEHEHPSGIVAPFAAEEALGKLIA
                     FQLKDKED"
     CDS             14513..14938
                     /locus_tag="ctg44_16"
                     /transl_table=11
                     /translation="MKDEQMLTEWPSHLPWLNQSQNDFTFPSDTYLLLYFWSMSCPNCH
                     QLTDKVLQDIKDMNVKVIGVHVPYIEEEKSMEVVLTYALDRGLAIQIVLDQNYEIVTTC
                     HVQGIPSFCLLSQYGQIITKTMGDVGWDKMLKKIAGL"
     CDS             15187..16164
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_17"
                     /sec_met_domain="PF00561 (E-value: 2.5e-08, bitscore: 27.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLWKVLKIVFVSLAALVLLVSVSVFIYHHFQLNKEAALLKGKG
                     TVVDVDGKKMNVYQEGSGKDTFVFMSGSGIAAPAYEMKGLYSKFSKENKIAVVDRAGYG
                     YSEVSHDDRDIDTVLEQTRKALMKSGNKPPYILMPHSISGIEAMYWAQKYPKEIKAIIA
                     MDIGLPQQYVTYKLSGVDRLKVRGFHLLTSIGFHRFMPSAVYNPEVIRQSFLTDEEKEI
                     YKAINFKQFFNADMEHELLQSYQNGSKSVNLPAPKETPVLILDAVSDQNRHSKYAIQNR
                     KDYEAFAAQFNTADIKELRGTHSIYLYQPDQIYKLSMEFMRKVR"
     CDS             16166..16837
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 127.8; E-value: 7.7e-39)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg44_18"
                     /transl_table=11
                     /translation="MKGYHILIVEDDVMIGELLQKILQREGYRVIWKTDGADVLSVIQK
                     VDLVIMDVMLPGEDGYQMSAKIKELGLGIPVIFLSARNDMDSKLQGLQIGEDYMVKPFD
                     PRELLLRMRNMLEHHYGTFTQIKHLYIDAVTKKVFNESLHDEVLFTAIERKIFFYLYEN
                     RDSILTKEHFFEYLWQLEDRNPNIVNVHIKKIRAKINDQAGEMIENIYGEGYRLNTVVK
                     K"
     CDS             16834..17820
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 59.4; E-value: 5.8e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg44_19"
                     /transl_table=11
                     /translation="MKLKTKYQLLLFTAVISVPMLLLAVSVLMSVIYDSMFKPMNHGMP
                     FHRSFAYPAMIVVFLISLLLLAFLFSKSIHSLLHKINLLNQTIRHLASDQRVPDKIEVK
                     RADEIGELIKSVNLLIERTTYRELELRQQEEIKKELLQKLRHDINTPLTALRLQLFYLE
                     DQCHGQAVFESLYQQIEYISELTNEFNLYSAETLESSYIVNEEVRLNELLETAVKKWDY
                     LYSMSGIELHYKAADQDVIWMSNALWMQRLFDNIFQNTLKHSKAEKMEVTIEHDNVFIR
                     DDGIGFDRNESSEGLGLKIIEDTCRLLAITYELHTNDSGTGFLFSKE"
     CDS             complement(18123..18893)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 111.8;
                     E-value: 6.8e-34)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg44_20"
                     /sec_met_domain="Pkinase (E-value: 2e-33, bitscore: 109.4,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALKLLKKLLFDRPLKNGVILNHQYKIEECLGMGGYGLVYLCTDI
                     LTQTPYVLKQLRPTKAKKEKEKVRFQQEIKLLNSIHHPQIPGFIDEFIIDGQAYYVMQF
                     IEGENIEELLFFRKQPFTELMALQLISQLLEIIEYLHDRLIFHSDIRTPNIIINDGRLC
                     LIDFGLAKQLTPEEMEEIKVRKQDDFFDLGETLLFLLYSQYKGKKKKNGTWLEELTLTK
                     EVTLLLKRLLGIEEEYQHTASIREDLNRAIQSVT"
     CDS             complement(18979..19836)
                     /locus_tag="ctg44_21"
                     /transl_table=11
                     /translation="MVKKWLIPFAVMLSVLFTFTYSASAAGVTAITGNNSFDTAMPIGY
                     WKYKNIDTTILEAGQDEAYFTFTANKGEKVYVRSTYQSAYTGMKIEIYDKNRIPVSQGT
                     EVINPNTFSSFIYANADAQNTTDTFYVKVSRGTYTGNMYFTLSIEDRIKSGSGTFQFSG
                     AAENKGNTSLSPSGSDSSVIKVDLTNQSGIPRDAIVTRVQTTATQTPSQGNTRHLIMTS
                     ENNEWRRALVNSSTSGSYDISLSDQLSVAKVWSFKYNTLATARSTMSNVKAKIDYEYDV
                     TKQF"
     CDS             19968..21152
                     /locus_tag="ctg44_22"
                     /transl_table=11
                     /translation="MRLNRQFIRTQLMAQNILSKNAPAKRENATENPAAVLEKAYSRLK
                     SQSSTGGINQFNYSKTSVSGNSGAFSKVYQSANDRTVTDTGEETVIQSQNHYESESDIR
                     IKILDEKYSRMNAINKTKSDPLGYIKDKYQNSKSPYFRSDLSAAERQAAYDNETEWLFK
                     GKAQNYNLQDAVFRNVTFHGEVEAENEKVYQRGQVNQQLQVLLNRNHIHIPEGTELTFT
                     ITPIDYQVRVSGSDDQDLIKQIEQVLQSGDNSKELFLHIMKSQSSDSAQFSEEAYQKYQ
                     AAREMYEVTGYHLKDLEVIDGRYVTPEGRDLMDVYKEELEKDPVQKQTASYAISYYRSE
                     LSKIAEAGYNAIPDFILSIDYSNGSLRDVGQSKSYGTGDTGWLEALKRQTGVNY"
ORIGIN
        1 ttcgctgaag ttagttgaag tgaagccgac aattttcagg attcaggaaa atgaaaacat
       61 agcataaagt aaagaccaat aataaggtag cacttcaaaa aacttcgctg aagttagttg
      121 aagtgaagcc gacaattttc aggattcaat gatctaacat aatcattgaa attttgaagt
      181 tgtcggcttt tttgttggaa aaaaatagag ataaataaaa attgaaataa ataatagaca
      241 aatatgatct gattgaaagg tcttttgaac aataatgagt tttaaaaaag ggagaattta
      301 gaatgttagt ttcgctgagt ttgtcatcat tattaacatt attttttatt atgcttatgg
      361 cttctgggat aagtggacta ttgtttttac atccgcgagt acccttgagt tttgtccgca
      421 ttcatattgg gatcttggct ttaccacttt tggtttcctt actgattctt gccaatagtg
      481 gtgtgagtgg aaatgttggc ccttggcact tagattcctt agcttgttta atgactttct
      541 ttgttcttgc aattggattc atcattcagc gtttttctgt acgttactta atgggggatc
      601 gatcttatcg aaaatatttt acgcttttta ctttcacaac aggagctgct tcaatgacat
      661 ggttaagtgg tgatctccgc ttgatggttc tattttgggg agcaactctt gttggtttaa
      721 ccttacttat taggttaaac agtgcttggc aagtggctag tgaagcagcc aaaatttctg
      781 gacggttatt tttgttaagt tggttttctt tgtttttcgc aatgatgtgg ctttttcatg
      841 ccacaggtca atggcagtta tcattggttg taacaaatga aagtttagct gggctgggag
      901 aatgggagag aacagggatt cagctattga ttgtactggc ggtgatcatt cctgcaggtc
      961 aatggccgtt ccaaagatgg ttggttgagt ctattgttgc tccaacccca gtttctgcaa
     1021 ttatgcatgc aggtttggta aatgctggag gaataatact aactcgattt tcacctctat
     1081 ttcatggtgg tatcgcttcg attatcttac ttctgcttgc tggcatttct gtattgattg
     1141 gaactggaat tagtttagtc caggttgatt ataaacgcca gttagtaggc tccacgattg
     1201 gacaaatggg gtttatgctc attcagtgtg cattaggcgc ctatatagca gccattattc
     1261 atcttatttt acatggttta ttcaaagcta cgttgtttct acaagctggt tcagcagtag
     1321 ggcgtcatga agtatcggct cgcactaatg aaagaacatc ctatttatgg gtcatggctg
     1381 gtcggatttt atccttagtt ataggtgttg ctttttggct cactgctcct ggagacgggt
     1441 atcacttaat cagtgcgctg atcttagggt ggtcattgtc cgtttcttgg actcagcttg
     1501 tcgcttttgg agagggccga attggccgaa ttgccggctt aactgtttta ggaggagcag
     1561 ccctcgtata ttttatcatt catcaccttt tctataagtg gctgcataca accatttttc
     1621 aaagtgttca acctccaatg tcagctgtca tgattgtcgt atgtctctta ctatttggca
     1681 gtgctttagg tacgtgggtt gctcgtcatc gttcttccgt ttttttcgcg gtactctatc
     1741 tttggttagt tcgattaggt gaagcaaaac caaagtcagt agagagtcac ccagactacc
     1801 ttaaacaata tatttcataa ggagctaatc tgagatgggc attacatccg tattaacgaa
     1861 agataatgta aacaagatag atacagatat tgatgttcaa gaaagggatc ttaacgtttt
     1921 cattacatct gccagccgag tgattgcgcc actttggcct atttctacat ttgctgcacg
     1981 taatccgtgg atgggacttg aaaaccaacc ttttgatcag gttgcaagtt ggttgaaaaa
     2041 cactcgtgat gttgatatat accctagtgc gtctatgatc cgttcagcaa agaataaagg
     2101 tgagattgat gaagattttg tggaaatggg gctgcagcgt tggcttgatt cacattccta
     2161 tcacattcca cgggacgtgg cagagcgatt ttgtcatgct gcattaaagt tagatcccct
     2221 gccttccgac cttttatcat cacatgagct ggagaaatta gtaagtgaat gtagtggatt
     2281 ggatcatatc gagaatgtgt ttatgcagcc actaagttcg tatatagaga atcaagatgg
     2341 tgaaaggcta gtcaatatac tagatcatca tgtcattaag tggagtaaat tatatcttga
     2401 tgactctcaa gcaggctgga caatgcctaa tcgtgaggaa ggtttctatc gtgcttggca
     2461 gcatctcatt caatatgatc cagcacttag taaaaagcag cgagaaaggg taaaaggttg
     2521 gccgaaagag gcacatttgg ctttacagga agccttattc gcactagaaa tcccagagtc
     2581 agaaatccag acttatcttg aaggtcattt actttcatta cctggatggg cagggatgat
     2641 gctttggcgc tcccagcaat cgagccacga acatgcactc ctaacagaat atttagcggt
     2701 tcgaatatcc atggagtggg ctcttataaa gccatactta cctttgacta atgaacgatc
     2761 taagaaaaca atttcaattg ctccccttat agcagcttgg attcattggg gtgggcttac
     2821 attagaagaa tggtcacaga tgacggccat tgaacaaaac gaatatttat catttgccta
     2881 cagctttgat gagaaacttc gcaagaaact ttggttagaa gcttgggaac aaacgtacac
     2941 tgatcgatta agccagaaga tcatctcgaa acaatgtgaa accggcggta aaaaatctgc
     3001 attagctcaa ttagcattct gcatcgatgt acgatcagaa ccttttcgtc gtcaactaga
     3061 aaaagaaggc ccgtttgaaa cgattggtat tgctggtttc ttcggggtgc cgattgcaac
     3121 ttgtgaactt ggcagtaaac acagtcatgc ttccttaccg atcatacaaa aaccgcaaaa
     3181 taaaataaaa gagttcgcag atgaggatgt attcaaaaaa tacaatcaac ggaagcaagc
     3241 aattcattct ttaagccata cctttaaaac gatgaagcag aatgcgcttt cgagcttact
     3301 actgcctgag ctaagcggac cttggcttac tctgcaaatg gcagcccgta gctttgtgcc
     3361 aagaaaggcg ggtcgtttca ttcgtaatct ccgtgaggct tggttgcgca aacctgatac
     3421 aaaactctcg cttcatcatg atgctacaga agcagaaatg cctgtgggtt ttactgatga
     3481 agaaaaagtg aactatgctc gccaagcatt aaaaatgatg gggttaacag aaaacatcgc
     3541 acccttggtc gtgatctgcg ggcatggcag tcaaagtact aataatcctt attccgcagc
     3601 ccttgattgt ggtgcctgcg gtggagcggc cggtggattc aatgctagag ttttagctgc
     3661 tttatgtaat ctatcagagg tacgagaagc tcttttagct gaaggaattc aaattcctga
     3721 ggatacggtt tttgcagcag ctgaacataa tacaacagta gatgaattac attggcttta
     3781 tgtaccagag ctttccgaag ctgcacaaga agcatttgaa caaattgaag ccgtgatgcc
     3841 gaaagtgaga catcatgtaa acgcagaacg tctagcccaa ttaccgaatt tccaatcgaa
     3901 gctaaaaaat ccgaaggctg aggcaaaccg atttgcggaa gattggagtg agatacgtcc
     3961 ggaatgggga ctggctcgta atgccgcttt tattatcggt aaacgtgaac taactcagga
     4021 ttgtgatttg gaaggcagag cctttctcca taattatgat tggaagcagg atgaaagcgg
     4081 tgaactccta gcaaatatta ttgcaggacc tggtactgta gcccaatgga ttaatttaca
     4141 atattacgca tcaacggtag cgcctcatta ttatggcagc ggaaataaag caactcaaac
     4201 cgttactgca ggtctcggcg ttatgcaggg gaatgcaagc gatttgttag ccggactgcc
     4261 ttggcaatcc gtcatggaat cagatcacga ggcctatcat tctcctcttc gtttattgat
     4321 actcatccaa gcacctagag aatatgtaga acggttatta aataatgatt cagcatttct
     4381 gcaaaaagtt caaaatggat gggtccgact ggctagtctt gatccagaag gatgttggga
     4441 aagctggtaa tgatgaatct aagcatttat caaatggatt tgttattcaa aataaaaatg
     4501 ataaacataa ggaagaggtg tgctgtatga atgtaaacca aaataaaaaa gtattatttt
     4561 tgacggatat tgaaaacggt ttggagccta ttttacaaga agcgactaac acttctgcag
     4621 agaatatgtt gactatacaa agctatggtg ccagtatttc acatccttat ggagaaatca
     4681 tgaggtctgt tatttttgcg atttaccagg aagatgttga ggagattttt gtagtaggaa
     4741 caaaagataa gaagactttc gcaggtaatg gactaactca acttgaaaca atgaaagata
     4801 aaatacaaac attggattat ctctttcaaa attgcaagcc tgaattttta ggtggtacgg
     4861 tcgatgaatg gctaaatgaa aatagcagtg acaccattga aaaaagtgtt gatatgattc
     4921 gacatcatcc actagtgccg tcacatgtta aagttcgagg tttacttgtt aatcataagg
     4981 atggaaaacc ctcaattatg gagggtcctg atgctaaaac aggtcaagcc atacctgatc
     5041 attgcttgtc atgatgaaat gcaggttcaa cttctaaacg cacctatata tggagaaagc
     5101 agttctaagg agattgtatg agcgctaatt taactgattt tgtcacgaaa acaatagagg
     5161 acatgaactc gtttgatcgt gaaaatatgg aatgtatgaa aaaactaatt agaaaagcaa
     5221 ttgattttta tcatcttaaa tcttatgaag aagttgagaa aacccattca ggaaatgttc
     5281 gatttttgca tgtccactct atgatggaag aaaatatgtt atccaaaatg atagtggtca
     5341 caagaaacgg taaaactgat ttggatattg aaggtgtata tgaaggatat gttgtaagag
     5401 aatattaatg agacgaaacc acaaatagaa tatgcaattt ttttgctcag gagatgtatt
     5461 agatatgaaa aaatcgaaag gttctattga atcagagatc agtaagtcca ttactcaatg
     5521 ggagaaggat tatcttgggc gggggtctgt atctgttaag actgatatac tgcgggacat
     5581 gatcatcgtc aatttaaaag ggattttaac accagccgaa tatgtagttt gtgggtcaaa
     5641 agagggtatg ttatctatca aacaaactcg ttcggagtta gtcgaatcag gtatagaagg
     5701 ccttaaggat attatcttaa aaataaccgg agaaaaagtg aaaagttttc atactgattt
     5761 aagctcccgg acaggtgaac gagtgatggt gtttaaatta tgtaatgatc tagagaaaaa
     5821 tttggaaaag atcttataat ctaaagaaaa taaatgttaa gacggtatgg aatttgttgt
     5881 gaattgaaca taaagaactg ccgattcttt tgttttacaa ttatggtatc attgataact
     5941 tttattcata tcctaagcgg acataaagag atgtcaattc atagtatact gtcttgttat
     6001 tcctgtcgaa agatctaaca tccgctgttg ttatgagcgg atgttttttt acatctattt
     6061 taaatacatg aatttgatgc tggtgattag tcacttgaac aatattaaat tcattttaat
     6121 tgaaaacatc cttgtcacct gccgggttcc cccaagtgtt tagtgacatg attatgagac
     6181 caatttcgta aagcttgatg ataaatttaa gcggtgaaca aaattgatat gctgtcttca
     6241 gtttcatttc acggaattag ctttaattaa atatatccaa aaaacggatt gacatatcga
     6301 aatataacga tataataatc gatatggaac caattgaagt attcaaagcc ttatcaaatg
     6361 aatcaaggct gcaaatttta caatggctga aggagcccga tcgtcatttt gcaccccatg
     6421 aagggattga tatgaacaca atcggggtat gtgtcagtca aataacagac aaattgaaaa
     6481 tgacgcaatc gacagcttct caatatctta ccatcctttt aagagccggc ttgattaagg
     6541 cggagcgtat tggaaagtac acatattaca aaagagatga agaagccatt gggaaacttg
     6601 ctgactttct taaaacagag atataaaaat aaacatcaaa agatgtttat ttttacacca
     6661 tacatatcga catattacga tgtgtttatt ttttataata acatatcgat aattcgtgat
     6721 atgtttattg ataattaagg agtgaatgtt ttatgtctaa cacttggaaa atttatattt
     6781 tagccattgt cagcttttta gttggaacct cagagtacat catttcggga attttggatc
     6841 aaattgctca tactctcggg atcactttag ctgccgcggg ccagcttatt accattttct
     6901 cacttgtata tgctctttct acacccgtac ttatggcgtt gacagcaagt atggatagac
     6961 gcaaattgat gatgtatgcc ctaggtttgt ttgtgttcgg taatgtcctg gcttttgtac
     7021 tgcctggtta tggatggttt attgcagcgc ggatcattat ggcgatggga gcaggtgtgg
     7081 tggttgtcac cgcattaacg attgccgcta agattgcatc ggaagggaag cagggaagtg
     7141 ccatcgctac ggttgtgatg ggatttaccg cttctttaat cattggtgtt ccgcttggaa
     7201 gaatgatagc agtagcatta ggctggaagt ctgtatttgg agcaattgct ttgttgggat
     7261 tgatcgcaat ggtcgttatt ttctttactc ttccgcatac tgaaggggat aagcctgtgc
     7321 ctttgcttca acagcttgct cttttcaaaa aacggaaagt ggctatggga ttatcaatca
     7381 ctttcttctg gctcggggga tattctgttg cttacactta tttgtcaccg tatctcttga
     7441 acatctcagg tataaacagc aagctgctta gcggtgtttt gcttatattt ggaattgcca
     7501 gtttggttgg atcaaagttt gggggatata gcaccgataa atggggagtg tcctttacac
     7561 tcgttggtgg gatgacgttg catatcgtca cactgattct gctgtcactt gttactcatt
     7621 cctatatcgg agtgttggtg attctcatat tatggtcgtt tgccgcatgg tctacaggtc
     7681 cgacacagca atttcacctg gctacaatag aaccggaaat gtcaggtgtt ttgcttagca
     7741 tgaatcagtc aatgatgcaa ttcgccatgg cggtcggcgc aggaatagga ggggtttttg
     7801 tggaaaacgt atcattggcc tcgattacct gggttggtgc gttaggggtt atgattgcca
     7861 ttattgcatc attgctgatt ttcaattcgc aaccgaaaca agcgctaaaa gatatcaatc
     7921 aataatttcg aaagatctaa catccgctcg ttatacaagc gggtgttttt tataagcgtt
     7981 caaagtcagt ccatgcatga gccttccaag ggccgacatc gttctgtatg tgtcgaaggc
     8041 gcactgaagc tgaaagggat ttcttaaggc tttgccgctg aagtacggta cgattgcctt
     8101 gatcgaacac tggaaacaca agagaacgta aacctgaaca tccgcgtaaa cgtcaaggaa
     8161 gttgccactt ggggagtaaa cacttgcatc atctcgctga aaggcctaga caatgcggat
     8221 gacatattcg tattgccgga agtaaacaca gcgcttgctc tgtttccgtt ggtttctgtt
     8281 gtcggttgca gctgattgct tactaatgct gacctgcatc tcggttgtga tgtcgataag
     8341 cagcgtaacc ttgtgaagag tgttactgtg gagtaagatg tttaacccct ttggatattt
     8401 tagccgaagg ggtttttagt atagatattt gatttaaatt acaggagact tcattcattt
     8461 aactaaagtc attgctttct taatcactaa agtttatttg aaaataatct cttgatttaa
     8521 tttcctcgaa gagattgttt gtcaatctat taggcatcag aatttttata acagaatgga
     8581 tcgtcttttt gacgttttgt ttatagaaca agaaaatatt caaaacataa gtggaaaatt
     8641 aggggtgagc tcctgttttt ctcgagagga tagcttgtca gcttttctat ttttaaaggg
     8701 taaaatattc tatttatact aattaatgta atttttagga taatatacaa aatccccctt
     8761 acttcgacaa ttgcaatctg gtattatcgt atcgcatggg agctatgtca atagactcta
     8821 tgcaaaaatt gagaggaggt ttacttatga aaagaaacca aaaagaatgg gaatctgtta
     8881 gtaaaaaagg acttatgaag ccgggaggta cttcgattgt gaaggctgct ggctgcatgg
     8941 gctgttgggc ctcgaagagt attgctatga cacgtgtttg tgcacttccg catcctgcta
     9001 tgagagctat ttaacatttg agaataggga gttgagcgta tttgcttata ctccttattt
     9061 tctcttaagg gggattttat atgtcatatg atcgtgttaa agattttgat ttgccagagt
     9121 tagcggttca tttacagcct catggtgctg taatgattga tagaaaaagt atgttttatt
     9181 tcagactcag tggacgtgga gcacagttgg cgtttctgtt atcaaaaaac aaaaaccttc
     9241 ataaaacggc acgtatttgg gagattatga aaaaagaaga gatgagtgct gaccaattaa
     9301 aagaagagct tagtgcccat ccatttacgg aggcttggac ggaagggctg ttagatcagc
     9361 ctttacacgt ttcgggttcg ctagattcat atttacctat tagttgtacc ttgcagttga
     9421 caaatgcttg taatttaagc tgttcgtttt gctatgccag ctcaggtaaa ccatatcctg
     9481 aggaactatc tagtgaacaa tggatattgg ttatgcaaaa gttagcagcc catggagttg
     9541 ctgatattac gctgaccggg ggtgaagcaa agctgatcaa agggtttaaa gaattagtcg
     9601 ttgttgcaag ttcgttgttt accaatgtga atgtatttag taatggattg aactggcgag
     9661 atgaagaagt tgaattactt agtcacttag gcaatgtttc tgtacagatt agtattgatg
     9721 gtatggataa tacacatgac caattaagag gcagaaaagg cggctttaaa gaaagtatga
     9781 ataccattaa aaaattatca gaagcaaaca ttccagtgat tgtcgctatg accattaatg
     9841 agtccaatgc tgatgaagta tcagatgtgg tggagcaatg tgccaatgcg ggtgctttta
     9901 tctttcgtgc aggaaaaacg ttatctgttg gacgtgcgac agaaggcttt aaggctttgg
     9961 atattgattt tgaagaaatg gttcaaatac agcttaggga agcacgtcat aaatggggag
    10021 atcgcctgaa cataattgat tgggagcacg aagagagttc gttcacaaca gatttttgta
    10081 caccaggata tcttgcttgg tatataagag cagatggata cgtaactcct tgccaattag
    10141 aagatttgcc gctagggcat attttagaag atagcatggc tgacattggt tcacctgctc
    10201 gtttgcttca gttaaaatgt gaagcaaaaa attgcaaatg tatagggaaa attgagctat
    10261 ctgaaccgga cttacctttt caaaaagaag tcaaggcagg gattcaggaa tgaatagtct
    10321 atcattggtg ttctggagta ttttagcagt tgttggatta ctgttattta ttaaattcaa
    10381 acccccaaca attgcttcac tactcttaag caaagatgag gcaaaagaaa taagcattca
    10441 atttataaaa gagtttgttg ggatagatgt agagaactgg gatttttatt cagtatattg
    10501 gtatgaccac gatacagtaa ataaacttca tcacttaggc atacttaaga aaaatagaaa
    10561 ggttttatat gatgttgggt tggtcgaatc atggagagtc cgtttcgttc accagaatca
    10621 atcatttgta gttggtgtca atgccaatcg agaaatcact tttttttatg cggatgttcc
    10681 gaaaaaaacc ctttcgggga agtttgaaca agtttctcca gagacactca agcagaggtt
    10741 aatggcttca cctgatggac tttggtctag agcaaatatg actggtactg gtaaaaaaga
    10801 ggaggatttt cgcgaggtca gtacttattg gtacatagcg gaagcgggag atattcggct
    10861 caaagtgact gttgaattac agggcggccg aatttcttat attggtactg aacaagaaat
    10921 actaacagat caaatgagta aagtcattcg agatgaacaa gtggaatcga cattcggagt
    10981 atctggtatg ctgggttcag ctttagcgat gatccttgcg attctcatcc ttgtatttat
    11041 ggatgtgcaa acaagcataa tcttcagtct tgttctgggt ttgttgatta taatatgcca
    11101 gtcattgacg ctgaaagaag atattcaatt aacaattgta aatgcttatg atgcaagaat
    11161 gagtgtcaaa acggtcagtt tattaggtat tttgtctaca cttcttacag gattattaac
    11221 aggatttgta gtatttatat gttcattggc aggaaatgcg cttgctggtg attttggatg
    11281 gaaaacgttt gaacaaccaa tagttcagat tttctatgga ataggagcag ggctcattag
    11341 tttaggagtg acttctctgc tgtttaactt attggagaaa aagcaatatt tacgaatttc
    11401 acctgagctt tctaaccgaa ctgtctttct atcaggtttt acctttaggc aaggattgaa
    11461 tatgagcata caaagttcaa ttggagaaga ggtcatctat cggctattaa tgattccagt
    11521 catttggtgg atgagtggaa atatcctcat ctccattatt gtatcttcct ttttatgggc
    11581 ggtgatgcac caagtaactg gatatgaccc aaggtggata cgttggctgc atctatttat
    11641 attcggttgc tttctgggag ttctcttcat caaatttggt tttatttgtg tattagtagc
    11701 tcatttcatt cataatttag tactcgtctg tatgccgctg tggcagttca agcttcagaa
    11761 acatatgcat catgatcagc caaagcatac ttcactctaa tgattaggag aagatttgat
    11821 gcaattgatg caagtacaaa atttaagcaa atgctatcga aatggtgatg gggttgaaca
    11881 tttgtctttc tcaattcaac gaggagaaat cgtggcgcta ttggggccaa atggagctgg
    11941 aaaaacaacg acaattcgat gtttgacagg tctctataag ccggataaag gagatatcct
    12001 cattgagggt tctcctccag gagatataaa tgttcaaaaa aaagtcgcgc ttattcctga
    12061 tcagccatat ttgtatcccg ctttaactgc tgctgaacat attcagttta gggcaagagg
    12121 atatcatcca ggtaaaaaag atgtaaaaga aagggtttat catgcattga aggaagtgca
    12181 cttggaggag aaagcaaacc aattgtgtgg tcagctgtca agaggccaaa agcagcgggt
    12241 tgtcctggcg ggggcgattg ttcaagacgc tttgctgtat atattagacg aaccgactgt
    12301 gggccttgat atcccatcaa aacagtggct ctctaactgg ttaaaaacta aaaccgatca
    12361 agggtgttca gcatttgtat caactcatag tctagagttt gttatagaga cagcagacag
    12421 ggtgatatta attagagacg gcaaactcat gcaggatttg tatgttcctc aattcgaaga
    12481 acaagcggaa tggagaaaag aagtgattcg tcttctaggg gaatggtcag atgaataata
    12541 tcatttcttt tttatggctt cagtcaaaaa ggcgttttgt aagtcaaggt caggaaaaaa
    12601 aaatgccttt tttgatcatg ctcctttttg ttggggccat cggatttcaa gtaagttttg
    12661 tttctagatc tacgacatgg gatatgagta ttgctggttg ggtacttaca ggtgttttta
    12721 tcctttatac ggcatttgga cttttttcaa atcgattacc aagtcaaatg gcagatatta
    12781 tatggcttta tggcactgcc acatcttttt caaaagttgt gtatagtgtt ttatttttca
    12841 gcgtcacttg gaaggcgttg ctttggatca tctcagccat attcggtgat gtattaattg
    12901 tgcttctgtc tggtgatcat atcaatttat taggccgatc cataattttt gtagggctct
    12961 tttttatcgc tgaagtgtgg ttgatgtcgg tctcttgtgc cagaacagtg aagaaaatga
    13021 aaagggtata cgttttagtc tttcttctaa tgttaggcat ttactccata tgtctttatc
    13081 gcttcttctt tctccaacat tcatctggga tatgggagag cattgcccgt tttattagtg
    13141 gcgttggatt agtgtttgat acattgtcac cgttgtatgt ggttgtattt attgggatta
    13201 tcacagtctc ttttatgaca attgctttta cgagccgtca ggtagaaatg aaggaatcgt
    13261 tggtgaaaga agctgaattc tgggaggaat ttcaagaacg tcaatttggt tcaggtcaaa
    13321 ttatacagaa accaaaaacg acttggtggg gcttgcaagg tctaaatggc atttggtctt
    13381 ttctgtggtt ggaactgttg ctttttaaaa aatatttatt ttttcatagc attcatacgg
    13441 tcatgctcag tggcgtcttt tatgtcgtca ttttcatgta tccagaatgg ttttatcttc
    13501 ttttctttct tatcgtctcg gcagtcatgt taagttccta ttattcagga attgtcagac
    13561 attctcaatc aggcaccctt catttattcc ccggtgccct ttggaaaaaa atcattattc
    13621 tagagctgac gaatacagtc tggttgtata ttctttactg tgtttctatt acttttatgg
    13681 cagttgggaa tttagtttat tggtatatat atggcttagg gatatatata tggttcatga
    13741 caataaggct ttttgctttt acccatacaa accgaaacga tattaagctt tcattgcctc
    13801 aatactacaa gtcatttttt atggcattag gcctgagcgg catttgtttg tatgtcattc
    13861 atttattgac tgctgactgg tatacattag tggtggtcgt ctgcataggg agcctaagtt
    13921 ggtgcctgtt ttatcgtttc agatagtggt tatgtagagt tattgtttta aaacgaggag
    13981 aggggctctt ttatgaattc aaatggtgat aaattgtcgt tatctgttca gaatttagcg
    14041 aatacaaatg agatcacaat tgttcaagcg ataggtgagc taaagaaatc gggaaaagat
    14101 gcaataccag ttttggttga ggccttaaaa gaggaaggct ctttgtgtaa tattgctgca
    14161 gctgttttag gtgagtttgg ggaagacgcg agtgaagcag cggaggagct atcatgttta
    14221 ttaaaaagtc atgccgaaga tacaagaatg gcagcggcga tttcattaat gagaatcggg
    14281 aagcccagtc tgccctttgt catcaaaatc gctcaagaaa gtgaagggca atcgtgcttt
    14341 tgggcatctt ggtgtattgc atggattgat ccgtcttgca ttgaacctaa gatgtataaa
    14401 tgtctaaaat acgagcatga acatccttca ggaatagttg ctccgtttgc ggctgaagag
    14461 gcgttaggaa agctgattgc ttttcagctg aaagataagg aggactgaaa ggatgaaaga
    14521 tgaacaaatg ttgactgaat ggccaagtca tttaccatgg ttgaatcaat cacagaatga
    14581 ttttacattt ccaagtgaca catatcttct tctttatttt tggtcaatga gctgtccaaa
    14641 ctgtcaccaa ttaacagaca aagtccttca agatataaag gatatgaatg tgaaagtaat
    14701 cggagtacat gtcccctata tagaagaaga gaaatctatg gaggttgtct tgacgtatgc
    14761 tcttgatagg ggactagcta ttcagattgt attagaccaa aactatgaga tcgtcacaac
    14821 ttgtcacgta caaggcatcc ccagcttttg tctattaagt caatacggtc agatcattac
    14881 taaaacgatg ggagatgttg gttgggataa gatgttaaaa aagattgcag gcttgtgaaa
    14941 ttttccgtct tgtatgtgcg acaaacggtt gaatattatg atgaaacggt ccttcctata
    15001 agcaggaagg ttttttaatg aaatattttt ttattagtag gtaaattcat caaatgttct
    15061 gctatgctcc aaatgtacac ctttccgtaa gggcaaagtt aaatgtgaaa ataaaactgt
    15121 tccaaagtta atcagaaatt tattttcata ttgtatcctt tcagtatcac gtgaaaggag
    15181 catcatatga aaacattatg gaaagtccta aaaattgttt ttgtcagctt ggctgctttg
    15241 gttttgcttg tatccgtctc ggtatttatt tatcaccatt tccagctaaa taaggaggcg
    15301 gcactgctga aaggtaaagg cacagtagtc gatgttgacg gtaaaaagat gaatgtgtat
    15361 caagagggaa gcgggaagga tacgtttgtg tttatgtccg gttcggggat tgctgcgcct
    15421 gcttatgaaa tgaaggggct gtacagcaag ttttcaaaag aaaataagat tgctgttgta
    15481 gatcgggcag gttatggata cagtgaagtg tctcacgatg acagagatat tgatacggta
    15541 ttggaacaga cgaggaaagc gcttatgaaa agcggaaata agcctcctta tattttaatg
    15601 cctcattcga tatccgggat tgaagcgatg tattgggcac agaaatatcc taaggaaatc
    15661 aaggccatta ttgcgatgga tattggattg ccccagcagt acgtcacgta taaattgagc
    15721 ggagttgaca gattgaaagt gagagggttc cacctgttaa cctcgattgg ttttcatcgg
    15781 tttatgcctt ccgctgtata taatcctgag gtgattcggc agtcgttttt aactgatgaa
    15841 gaaaaagaaa tctataaagc cattaacttt aagcaatttt ttaatgcaga tatggagcat
    15901 gagcttttac agtcttacca aaacggcagc aaatctgtga atctgccggc accaaaggaa
    15961 actcccgtct tgattttaga tgcggtctct gaccaaaata gacattcaaa gtatgctata
    16021 caaaaccgaa aagactatga agcgtttgcg gctcaattca atactgccga tataaaggaa
    16081 ctgaggggaa cacacagtat ttatttatat cagcctgatc aaatatataa actgtccatg
    16141 gagtttatga gaaaggttcg ctaggatgaa gggatatcat attttaatcg tggaagacga
    16201 tgtgatgatt ggtgaattgc tgcaaaagat tttgcagcgt gagggatatc gtgtgatatg
    16261 gaaaacagat ggagcggatg tgctttcggt gattcagaag gtggatttgg tcattatgga
    16321 tgtgatgctg ccgggtgaag acgggtatca aatgtctgca aaaatcaaag agctggggct
    16381 gggcattccg gtaatttttc tttcggcccg taatgatatg gacagcaagc ttcaaggttt
    16441 acagatcggc gaggattata tggtaaagcc ctttgatccg agagagctgc tattaagaat
    16501 gcggaatatg cttgagcatc attatgggac ctttacgcaa atcaaacatt tgtatattga
    16561 tgcggtaacg aaaaaagtgt tcaatgaaag cctgcatgat gaggtattat ttactgcgat
    16621 tgagcggaaa attttctttt atttatatga aaatagagac agtatcctga caaaggaaca
    16681 tttctttgaa tatctatggc aactcgaaga tagaaacccg aatattgtca atgtgcatat
    16741 taaaaaaatt agagctaaaa tcaatgatca agcgggtgag atgattgaaa atatatatgg
    16801 agaagggtat cggctgaata ccgttgtgaa gaaatgaagc ttaagacaaa atatcagttg
    16861 ttattgttta cggccgtcat tagtgttcca atgctattgc tggcggtaag tgttttgatg
    16921 tcggtgattt atgacagcat gtttaaaccg atgaatcatg gtatgccctt tcacaggtcg
    16981 tttgcgtacc cggcaatgat cgttgtattt ttgatatcac tcttattgtt agctttttta
    17041 ttttcaaagt cgattcattc tctgttgcat aaaatcaatc tattaaatca aaccattcgg
    17101 catttggcga gtgatcaaag ggtgcccgat aaaattgaag tgaagcgtgc tgatgaaatc
    17161 ggggaactga tcaagtcggt caatttgtta attgaacgga cgacatatcg tgaactggag
    17221 ctgagacagc aagaggaaat caaaaaggag cttttgcaaa aactgcggca tgacattaat
    17281 acacctttaa cggctctcag gctgcagtta ttttatttgg aagaccaatg tcatggtcag
    17341 gctgtattcg aatcattgta tcagcaaatc gaatatatct cggaattaac caatgaattc
    17401 aatctatatt ccgctgagac gctggaaagc tcttatattg taaatgaaga agtgcgtcta
    17461 aacgagctat tagaaacagc ggtgaaaaag tgggattatt tatacagtat gagtgggatt
    17521 gagctgcact ataaggcggc agatcaagat gtgatatgga tgagcaacgc gttatggatg
    17581 caaaggctgt ttgataatat ttttcaaaat acgttaaagc attcaaaagc tgaaaagatg
    17641 gaagtcacga ttgaacatga caatgttttt attcgtgatg acggtattgg atttgatcgg
    17701 aatgagagca gtgagggact tgggttaaag attattgagg atacatgcag gctgcttgcg
    17761 attacttatg agctgcatac aaatgatagc ggaacggggt tcttgttttc aaaagagtga
    17821 ccccgctgat gtttttcttt ctcctataaa atttatataa tagggagaaa gaaatggggt
    17881 gaacagcata tgtttaaaaa aatcatcaaa acgattaagt acctctcaag cagttctagt
    17941 gaccgatatc gcagacaccg gcattacagc agcagccggc gcagacatta tcgcagctac
    18001 agcagctcgg gcaaaagaag acactacgac cgttatggcg gcagtcatcg ttacaaacgc
    18061 cggagctaca gcagcagtta atccaaaaaa gttcttgttc cgcttttggg acaagggttt
    18121 ttttatgtga ccgattgaat ggcccggttt agatcctcgc gaatggaagc ggtgtgctga
    18181 tactcttcct caatgcccaa taatcttttc agcagcaagg ttacttcctt tgtcagtgtt
    18241 aattcctcca gccaagtgcc gtttttcttc ttttttcctt tatattgaga gtacagcagg
    18301 aataacagcg tttctccgag atcgaagaag tcatcctgtt ttcgtacctt tatttcctcc
    18361 atttcttcag gagtcaattg tttggcaagg ccgaaatcga tgaggcagag cctgccgtca
    18421 ttgatgatga tattaggcgt tctgatgtcg ctgtggaaga taaggcgatc atgcaggtat
    18481 tctataatct caagcagctg cgaaatcagt tgtaatgcca taagctctgt gaacggctgt
    18541 tttcgaaaaa ataataattc ttctatattc tctccctcaa tgaactgcat gacataataa
    18601 gcctgtccgt ctatgatgaa ctcatctatg aagcccggaa tttgcgggtg gtgaatgcta
    18661 ttgagcagtt ttatttcctg ttggaatcgg actttctctt tttccttttt cgcttttgtc
    18721 ggccgaagct gttttaagac ataaggtgtt tgagttagga tatcggtgca caaataaacc
    18781 aaaccgtagc ctcccatacc gaggcactct tcgattttgt attgatgatt taagataacg
    18841 ccgttcttta gagggcggtc aaatagcagt ttttttagaa gttttaatgc catgtctgca
    18901 cttcccttgg ttgtactgac tatagtttac cttctagaca gagaataaaa aagagccgga
    18961 tcaccggctc ggtataagtt aaaactgctt tgtcacgtcg tattcataat ctatttttgc
    19021 ttttacgttg ctcatcgtcg atctggctgt cgctaatgta ttatatttaa aactccatac
    19081 ctttgccaca ctgagttgat ctgacaaaga gatatcataa gaccctgaag tcgagctgtt
    19141 tacaagagca cggcgccatt cgttgttttc gctcgtcatg atcaggtggc gtgtatttcc
    19201 ctggcttggt gtttgagtgg cggttgtctg aactctggtt acaatggcat cacgcggtat
    19261 cccggattgg tttgttaaat caaccttgat cacgctggaa tcagaacctg aggggctaag
    19321 gcttgtattt cctttatttt cagcagcgcc gctgaattgg aatgttccgc tgcctgattt
    19381 gattcggtct tcaattgaaa gtgtaaaata catgtttccg gtataggtgc ctcgtgacac
    19441 tttcacataa aaggtatccg tcgtgttttg ggcgtctgca tttgcataaa taaaagaaga
    19501 aaacgtatta gggttaatga cttctgtccc ttgagaaaca ggtattctat tcttatcata
    19561 aatttcaatt ttcatccctg tatacgcgct ctggtatgta ctcctcacgt atactttttc
    19621 tcccttatta gctgtaaaag tgaaataggc ttcatcttga ccagcttcca gtattgttgt
    19681 atcgatattt ttatatttcc aataaccgat cggcattgcg gtatcaaatg aattgtttcc
    19741 tgtgatagca gtgactccgg cagctgatgc cgaatacgta aaggtgaata agacagacag
    19801 cataacagcg aatggaataa gccatttttt caccatgcaa acaacctcct tttatttcca
    19861 tcatacataa taacgattta ggtgtaaata aatgtttttt gaggttaata tatacattat
    19921 ctttgccgat aaaaaagaat aagagagaat actcgggagg gaattcaatg cgtctgaatc
    19981 ggcaatttat ccgcactcag ctgatggcac agaacatatt gagcaagaat gcgcctgcca
    20041 aacgggagaa tgcgactgaa aatccagcgg cagttctgga aaaggcatac agcaggctta
    20101 agtcacaatc ttcaactggg ggaatcaatc agttcaatta ttctaaaacc agcgtgtcgg
    20161 gaaacagcgg ggcgttcagc aaagtgtatc aatcagcgaa tgatcgaaca gtgacagaca
    20221 caggggaaga aacagtgatt caatcccaaa accactatga atctgagagt gatatcagaa
    20281 tcaaaatact agatgaaaaa tacagcagga tgaatgcgat taataaaaca aagtctgatc
    20341 cattaggcta tattaaggat aagtaccaaa attcaaagtc tccttatttc agaagtgatc
    20401 tgtcagctgc agaaagacag gccgcttacg ataatgaaac agaatggtta ttcaaaggga
    20461 aggcgcaaaa ctataacctt caggatgctg tgtttcggaa tgtcacattt catggggaag
    20521 tggaagctga gaatgaaaag gtgtatcagc ggggacaggt taaccagcag ctgcaagtac
    20581 tgttgaatcg aaaccatatt catattccag aggggacaga gctgacgttt acaatcacac
    20641 cgattgacta tcaggtgcgg gtaagcgggt cagacgatca ggatctgatc aagcaaattg
    20701 agcaagtgct gcaatctgga gacaacagca aagaactatt tttgcacatc atgaaaagcc
    20761 aaagcagtga ttcagcacaa ttttccgaag aggcctatca aaagtatcag gctgctcgtg
    20821 agatgtatga agttacaggc taccatttga aggatttaga agtgattgat gggcggtacg
    20881 tcacgcctga gggacgtgac ttaatggatg tatataagga agagcttgaa aaagatccag
    20941 tgcagaaaca aacggcttct tatgctatat cttactatcg ttcagagctc agtaaaatcg
    21001 cggaagccgg gtataatgcc attccggatt tcatcctttc aattgattac agcaatggat
    21061 ctctgagaga tgtgggacaa agcaagagct atgggaccgg agataccggg tggcttgaag
    21121 cattaaagcg tcaaacgggt gtgaattatt aggtaagctg ttcatgtagg acagcttatt
    21181 ttttatgaga atctaagggg tgaattaatc ccaatattca aataatttta ttatttttat
    21241 ataaaagatt ttaaaagaag tgaacgattc aaaactctga acaaaggtgt ttgcctgaaa
    21301 aaaacaattg tattttccag agaaatttat tatgatgaaa taagtaattt aggagattat
    21361 ataacaattt taagtttgaa ttttctgatt gttatcactg attcatgtga aggcaagcag
    21421 gtctgctgtt ttctcattta tgagtatttt gttaggagga ggaagaggag tggcaaataa
    21481 agaattaaag aggggcctgg gcgcgcgcca tattcagatg atcgccttgg gcggtacaat
    21541 cggtgttggc ttgtttatgg gttctgccag cacgatttca tggactggcc catctgtcct
    21601 tctggcttat gcaatatgcg gaatttttat cttttttatt atgcgtgcga tgggtgaaat
    21661 gctgtatgtc gagccgagca caggttcttt tgcgacgttc ggccatcaat atattcatcc
    21721 gatggcaggt tatataacag catggagcaa ctggttccag tggattatcg tcggcatgtc
    21781 agaaattatc gctgtcggtt
//
