LOCUS       c00011_JAHCUP0..       13659 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAHCUP010000001.1 MAG: Lactobacillus crispatus isolate 118_0
            Scaffold_1__SCF_001__sum_of_lengths:_941018_bp, whole genome shotgun
            sequence.
ACCESSION   JAHCUP010000001
VERSION     JAHCUP010000001
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 07:25:49
            Original ID  :: JAHCUP010000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 212495
            Orig. end    :: 226154
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1215)
                     /locus_tag="ctg11_213"
                     /transl_table=11
                     /translation="MNKIWLVAKETYRREVKTWSYLLMILAPFLLVFFSFVIGMVSAGG
                     SDDNYVGVVTSNSALKQAIKKSEDFDNYSTEAKAKKAYKDEDIDGYVLIEQKNNQLAAT
                     YYSDEKMDSDLKSELLTSLNTAQQQLNLSKAKLTTKQTQSLATRAQFKQQVKHVDKKSF
                     DNDPVKQISFWVLLIILYMLVITYTQVTAQDIATEKGTKIMEVIFSSMPGGDYFTGKIL
                     GIFGEIITQVLIYVVGFVAVYCAAPYIDGFSDLFRQYKPMIDQAIGNLASWGLVFTIIG
                     LVLFIIFAAFCGALVAKSENANKAVGPLSTLMLIGFLFTVNMQSGGDTIFAKVLSYIPF
                     LSSFVMPARVIMGNATNLEAAISALIALAATVASFIWIRKIYPNLILQTDDVGPWQNFK
                     RSLRG"
     protocluster    1..13659
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[216792:222275]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4298..9780
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..13659
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13659
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(1208..2104)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 168.6; E-value:
                     3e-51)"
                     /gene_kind="transport"
                     /locus_tag="ctg11_214"
                     /transl_table=11
                     /translation="MLKIEHLNKSFGSTQVLFDVSFSVSDGRILGLVGKNGSGKSTIFH
                     SILKFVDYDGQISIDGHSFNAKDYDNIGYLPEERSLMPKLTISDQVVFLASLKGMPAKK
                     VKEELPDWLSRLAVKGIPMDKIKSLSKGNQQKVQMIATLIHQPKLIILDEPFSGLDPVN
                     VDLMKQLILEEKRKGATIIFSDHDMRNVEELCDDVVMINDGHIVLNGPVNEIKNSFGLT
                     RIFVRTDKSATELSALPGVKDIILQNNGMKLLILADEKYGKDIFNQLSAGQYIQTFDQE
                     PPTLDEIFKMKAGARHE"
     CDS             complement(2122..2544)
                     /locus_tag="ctg11_215"
                     /transl_table=11
                     /translation="MNNEKFARENKRIIEGMGIGALVGPILALVMMYVKTAGSPQPFQI
                     IMSIGAGLAFGLMFGGIMSASLVLNKTVASKIPWQKKVLKLAPQVIGTGVVVASAGVVI
                     TLVTNWGSVDIVKTIFSTDTLWQFFDGVLLGLITIR"
     CDS             complement(2571..2762)
                     /locus_tag="ctg11_216"
                     /transl_table=11
                     /translation="MLYLIYIVLGLLIILAVNYAVTAFLAVHDLLENREKDQLSFGDAF
                     KKYFAKNNIPTKFSDLFN"
     CDS             complement(2895..3104)
                     /locus_tag="ctg11_217"
                     /transl_table=11
                     /translation="MIEVTLDFMLLKRKMSSKELAEKVGITPANLSILKTGKAHGVRFD
                     TLSKICEVLDCQPGDLLVYKKDEE"
     CDS             complement(3119..3658)
                     /locus_tag="ctg11_218"
                     /transl_table=11
                     /translation="MKKLILNLLTIFAWIYQIFCVIGIIMWIVMGGVVLFGIHNPDFRA
                     GFESGRGIKGVSVDNYIGAIVVVLLSLIMMSVAAFLICRYARLIVKNIKQEVYFADSNL
                     NLLKKLLISVAGYTLISIIDYIIFITHRTWFAKSSNNVLYPSGVTTGLLFLAVLYVVYL
                     VFKYGMKVQEDADSII"
     CDS             complement(3663..3845)
                     /locus_tag="ctg11_219"
                     /transl_table=11
                     /translation="MLPEKKRQIGSIIGMLIMMAILVFANLGGTWSVLRITLLVIGVTG
                     VIGSAIYRIIHILRG"
     CDS             complement(4298..4492)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_220"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.7e-07,
                     bitscore: 27.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKEMNYKELEKVSGGTNWLGVGGSCLSGFIDALPSGSGMIKGCV
                     EGAVKDFAKQNRHKKHKHR"
     CDS             complement(4510..4761)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_221"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 4.3e-14,
                     bitscore: 48.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKFETLTYEELSAVFGGNGGKARRRRKITNCAKAIGMGALKDGL
                     KYGIAGTAFGTPIGTVGGAIFGANVGIISGSVSCVSHL"
     CDS             complement(5354..5551)
                     /locus_tag="ctg11_222"
                     /transl_table=11
                     /translation="MKRIIISKDEVLLSGILGGSGSVDDIGLTDTEHMLPLYSKKGGNH
                     KRDVYLENPKFFQSSFHRGR"
     CDS             complement(5552..6856)
                     /locus_tag="ctg11_223"
                     /transl_table=11
                     /translation="MNKKKILMLMLSPAVLLMMNSTIVHADEGNTSQENKSEVVSKTEN
                     DDKNVSESEQKTSSKNEAAQTQNKQEEEPAASEDQNNQSQNTNNQDPNNANEEDSEDDE
                     DEVSVEDYENNVKDFHRVKMQEVKDLLAEKNNQEHLMYIGRPTCYYCRQFSPDLKDFNE
                     IVKGKLLYFNIDAEEGAHEYAFKEIGIPGTPTTMRFINGKIISAWVGGEKTGQELYNFL
                     YSDAANKLVEQAVIKDQPKDDNTTESESNEIPEVTVAEDDQTQSSNDVAITDFVENSVF
                     ENAANVASSTADLTKVTTGNQEYAAPRAETKKKTVKKPVKPKIVATKVKKTAKSHKKNI
                     ILAAVSEKHGSVKENKQFDSVKVQSKPYSAVKNNQNRITKLKRLENDTIKNGSTQSLPS
                     TGEKDNIWGQLIGMISILISLVLGISLGKKTKEEK"
     CDS             complement(7011..7607)
                     /locus_tag="ctg11_224"
                     /transl_table=11
                     /translation="MNNKDYESTEYYSYKFKNFSTMIIIPMAILVLILIVGSFFATRQS
                     TVTSTGIVEPQNTLNIANRNYHEGQIVRRNREKWLVHLDDKQENTVHLFPMIKAKRTVN
                     VVTYFPGNKIGAIKKGQTLYFQVANASGTMDRLVGKVKEIGVYPINLRGNNVYEVICKA
                     KSKKNLKYGMEGNATIITGKSTYFEYFKDKILNQN"
     CDS             complement(7618..9780)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 313.4; E-value:
                     5.1e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_225"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1069.0,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.6e-43, bitscore:
                     143.7, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLQYKSIYVPQVDESDCGVACLAMILKKYHSRVFLAHLRHSART
                     NLEGTTALGLVKTAQAFNLKTEAVKADMSLFDPDADIQYPFIVHVLKQGELLHYYVVIK
                     ATKNYLVIADPDPSVGLTKMSKEKFSQEWTGIALFMVPNDDFEPLKEKKQNLWSLFPYM
                     FKQKKLVTNIILAALLMTIISICSSYFLQGLIDTYIPSGTYQTLSILAIGLLIAYVFNS
                     IFSYGQNFLLDVLGQRLSIDLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDAL
                     ASTVISLFLDLSIVIVMGIVLAIQNSTLFVITLLSLPIYAVVILSFSKKFEKMNNDQME
                     SNAVLSSSVIEDIQGIETIKALNSEQTRYRKIDSQFVDYLKKSFRYSKTESLQSALKTF
                     IQLSLNVIILWVGAKVVMNGQMSIGQLMTFNALLSYFVDPLQSIINLQPTLQSANVAQN
                     RLNEVYMVKSEFQKDAQIRDAKQLAGEIEYHHVDYHYGYGVDVLKDINLKIEPNDKLAI
                     VGMSGSGKSTMVKLLVDFFSPSKGKLTFNGFNSTKVDKHVLRSYVNYVPQTPYIFSGTI
                     KENLLLGSRPDITEKDILKACQIAEIESEIEQLPLQFETKMDENAKILSGGQKQRLTIA
                     RALLSPAKILIFDEATSGLDTITEKKVVDNLMKLKDKTIIFIAHRLAIAQRTNNIVVVD
                     HGQIVEQGSHEKLMQKHGFYYNLVEN"
     CDS             complement(9904..10704)
                     /locus_tag="ctg11_226"
                     /transl_table=11
                     /translation="MSKFPIIVCDDDKDLANQMAKNINASIQDLIDDNEGYAELNESVT
                     FVANDFAQAVGYIVTNDIKNGIYFLDIELSRESKAKNGVDLAEFIKKNDENAQIIFVTA
                     YDKYAPLTYRRRIGAIDYISKSMSSDKIIQRIEETLCNAFDNLSNRIKFSQRDFTYKIG
                     RRVCKVAEGDILFIEHSTTQHKVHMVTENGEVEYKANITQIDKENPFLAKVSQSSLVNP
                     KNISAIDTKERIIIFDNGQMVTYSRSYKAVVKKLVDKFENIKVE"
     CDS             complement(10697..12025)
                     /locus_tag="ctg11_227"
                     /transl_table=11
                     /translation="MEKIVLFLFLNVFSSLADVWCFFKISRVRSKKRQILFLCIANIFL
                     GLLLSIGNIGVIFTNILETLLFVLYLRKNNTLEILFGSIILVCTLDLLVDIVSDMITQV
                     MSFTLIGQLSLRFLLILMMIVAIKLGNGKIYNYLANQNNKIFVGILAYTYVSTVSISII
                     YIQSKSFTPLTLFFSLYILIQTIFAIFIYHEMTMVQEKLLNKKDQEKLKQQQHQLEEYA
                     SYLEKSEDDLRAFRHDYKNILNSLKVSAQEGNVQEVIQKLDKYTETNLNSKALLKYKDL
                     NHIYVKSIKSIIIPKITELYNLDIPYNFECRNNIRNLPDHVDELDLVRIIGITFDNAIE
                     ESKALIAEKHDIRSAEVQIMVYSDDPDEFEFEIRNKIQNKNISTSQIQQRGFTTKKDHK
                     GLGLANIKEIESKYPDMSISYTIQDGWFDFYMTIDTEDGEEDE"
     CDS             complement(12013..12144)
                     /locus_tag="ctg11_228"
                     /transl_table=11
                     /translation="MKKQNVKKTVLKEEELTKVVGGSTAHVGFNFLSKKLWNNIWKR"
     CDS             complement(12262..13659)
                     /locus_tag="ctg11_229"
                     /transl_table=11
                     /translation="MFVGRHQELEQLNQAYQENDFQFTVIYGRRRIGKTSLINEFLKDK
                     KSIYYVALEENAEDNLKRFSDAISIFKNTDQGGKEKFANFEECFKEITHLAQKQRVILV
                     IDEFPYLAKAYPTISSMLQSYIDHEFKETNLFLILCGSSMSFMERQVLGYQSPLYGRRT
                     LALKLEPFKLSEAHEMLPKLSKEDAFIINTVCGGVPQYLSYMSDSMSVADNIKKNFLSK
                     SGRLFDEPNNLLQQELRDPTNYNSIINAIASGASKHSKIAQSAHLQTGPLTTYLNNLID
                     LGIVEKKLPVTEQKKSKSKNIVYRICDGMFRFWYTFVGKQTDLIERGLTDLAWVKVQKG
                     LSDFMGPEFEKYSQDFMWSQDMNEKIVPNPFIHLGNWWGTDKRTHQQVELDIVGFSDDE
                     RDGYFGECKWKNEPISRSVLEKLITNSEIFKYPLKHYYLFSKSGFTDSCQELAKKINCQ
                     LFTFEEI"
ORIGIN
        1 ctagcctctc aagctacgct taaagttttg ccatgggccg acatcatctg tttgcaaaat
       61 caagtttgga tagatttttc taatccagat aaatgacgct actgtagcgg ctaaagcaat
      121 taaagcagag atagctgcct ctaaattagt tgcgttaccc ataattactc tagctggcat
      181 tacaaatgat gatagaaacg ggatgtacga taatacttta gcaaaaatcg tatccccacc
      241 tgattgcata ttgactgtga acaagaaccc gatcaacatc aatgtagata gtggtcccac
      301 cgctttgttg gcattctcgc ttttagcaac caaagcgcca cagaaagctg caaagataat
      361 aaacaatacc aagccgatta tcgtaaacac caatccccaa gaagccagat tgccaattgc
      421 ttgatcaatc atcggcttat actgtctaaa taaatcgcta aagccatcga tgtatggggc
      481 cgcgcaataa actgccacaa aaccaacaac ataaattaac acttgggtga taatttcacc
      541 aaaaatacct aaaatcttcc cagtgaaata atcgccacct ggcatactcg aaaagattac
      601 ttccattatc ttggtaccct tctccgtagc gatatcttgt gctgttactt gcgtataagt
      661 gatcacaagc atgtacaaga taatcagcaa aacccagaag gaaatttgct taacaggatc
      721 attatcaaag ctcttcttat caacatgctt aacttgttgc ttaaattgcg ctcgcgtagc
      781 taaagactga gtctgttttg tcgttagctt ggccttactt aaattcaatt gttgctgggc
      841 ggtgtttagg ctagttagca gctctgattt tagatcactg tccatttttt catcactata
      901 gtaagttgca gctaattgat tattcttttg ttcaattaaa acatagccat cgatatcttc
      961 atctttatac gcctttttag ccttagcttc agtgctatag ttgtcaaagt cttctgactt
     1021 tttaattgct tgctttaagg cagaattaga agtaactacc ccgacatagt tgtcatcact
     1081 gccgccagct gataccattc cgataacaaa tgaaaagaag acgagcagaa acggtgctaa
     1141 aatcatcagc aaatatgacc aagttttcac ttctctacgg taggtttctt ttgcgacaag
     1201 ccagatctta ttcatgacgc gcacctgctt tcattttgaa aatctcgtct aaagttggag
     1261 gttcctggtc aaaagtctgg atatattgac cggccgaaag ttggttaaaa atatccttac
     1321 catatttttc gtctgcaaga ataagcagct tcattccatt gttttgcaaa attatatctt
     1381 ttacacctgg taaggctgat aattcagtag cacttttgtc tgtcctgaca aaaattcgag
     1441 ttaggccaaa gctgttctta atttcattta ctgggccatt caagacgata tgcccatcat
     1501 tgatcattac gacgtcatcg cacaattctt ccacgttacg catatcatga tcagaaaaaa
     1561 tgatcgtagc gccttttctt ttttcttcca aaatcagctg cttcattaga tcaacattaa
     1621 caggatctag tccactgaat ggttcatcta aaataatcaa tttaggttga tgaattaaag
     1681 ttgcaatcat ctgtactttt tgttggttac ctttagacaa agacttaatc ttatccatgg
     1741 ggatcccttt aacagccaaa cgtgataacc aatcaggcaa ttcttctttt acctttttag
     1801 ccggcatccc tttaaggcta gccaaaaaca ctacctgatc tgaaatagtt aacttaggca
     1861 tcaaacttcg ctcttcaggc agatagccaa tattgtcata atctttagcg ttgaaagaat
     1921 gtccatcaat actaatctgg ccgtcataat caacgaattt caaaatacta tgaaagatcg
     1981 tcgacttacc cgacccattt ttaccaacca gtccaagaat acgcccatct gacacactga
     2041 agctaacatc aaacaaaacc tgtgttgacc cgaagctttt atttaggtgt tctattttta
     2101 acataatttt tcctcaactt tttatctaat ggttattaga cctagaagta caccgtcaaa
     2161 gaactgccat aaagtatcgg ttgaaaaaat tgtttttaca atatcaactg acccccaatt
     2221 ggttactaaa gtaatcacta caccagctga agcaaccact actcctgtac caataacttg
     2281 aggggcaagt ttcaacactt tcttctgcca tggaatcttt gatgcgaccg ttttattaag
     2341 gactaagctt gcggacatga tgccaccaaa cattagaccg aaagccaatc cggctccaat
     2401 cgacataata atttgaaaag gttgaggcga accagcagtc ttaacataca tcatcacaag
     2461 agctaatatt ggtccaacaa gtgctccaat tcccatgcct tcaataattc gtttgttttc
     2521 acgagcaaat ttttcattat tcattgttct tacctcaagg aaattttcag ctaattaaac
     2581 aaatccgaaa acttagtcgg aatgttgttc ttggcgaagt atttcttgaa tgcatcccca
     2641 aaactcaatt gatctttttc tctattttca agcaaatcat gaacagctaa gaatgctgta
     2701 acggcgtaat taacggctaa aatgattaac aaaccgagca caatataaat taagtacagc
     2761 attgttcttt cctccaattc agcgattatc tcccaggaaa taatctttta tccttttaaa
     2821 ttaatcatat ccccatcatt tatgtaaaag gtaaaaccgt ccaattctgt catttttcgg
     2881 actgattttg cattttattc ttcatctttt ttataaacta ataaatcccc tggttgacaa
     2941 tccaagactt cacagatctt gctcaacgtg tcgaagcgaa cgccatgcgc ctttcctgtc
     3001 ttcagaatcg acaggttagc cggcgttata ccaactttct ctgccaactc ctttgaagac
     3061 atctttcgct tcaagagcat aaaatctagt gtcacttcaa tcatctatat caacctttct
     3121 aaataatcga gtctgcatcc tcctgaacct tcattccgta cttgaatacc aagtagacta
     3181 cgtatagtac tgctaggaaa agcaaaccag ttgtcacacc acttgggtat agtacattat
     3241 tcgaggattt agcgaaccaa gtgcggtgag ttatgaaaat aatgtaatct attattgaaa
     3301 taagggtata tccagcaact gaaattaata atttcttgag taaattcaaa ttactatcag
     3361 caaagtaaac ttcttgcttg atattcttaa caattaatct ggcatatcga cagattaaaa
     3421 aggctgcaac gctcatcatg atcagtgata gcaacacaac cactattgca ccgatatagt
     3481 tatcaactga tacgcctttt atacccctac cactttcaaa gccagcacga aaatccggat
     3541 tatgtatacc aaataacaca acacctccca taacgatcca cataattatt cctatcacac
     3601 aaaatatttg gtaaatccaa gcaaaaatcg taagcaaatt taaaattaat tttttcattt
     3661 ttctatcctc tcaaaatatg gatgattctg tatatagcac tgccaattac acccgttact
     3721 ccaattacta ataatgtaat tctaagaaca ctccatgttc cgcctaagtt agcaaacact
     3781 aagattgcca tcattatcag cattccaata attgaaccta tctgtctttt cttttctgga
     3841 agcatatcta tccctctctt ccataaaact atctatctct ttctcgtctt ttataattat
     3901 tgtattacga taatttataa ttgcaataca gaaataaaat atttttttgg gataataaaa
     3961 aaataccaaa ttagtcgtta aactaacttg gtattatgtt ttatcttcca agctactgct
     4021 ttttactttt cttcttatag taagagttca tgaaaatatt cataaagata acaaaggcta
     4081 cactttcaac tatattccaa aatactgttc caaagcttaa tgttttgtac tgaaaatagt
     4141 cccataccaa tcctattaac agggccaaaa taccagcgat gatacttctg tttctaactt
     4201 ggcgctcggt taaaatttta tttttcataa tttttacccc attattatca tatcgaaaaa
     4261 taggaaatct attaaccgaa ttttctattt tttaatatta tctatgttta tgttttttat
     4321 gtctattttg tttggcgaaa tctttaacag cgccttctac acatcctttt atcataccac
     4381 ttccgctagg gagcgcatca atgaaacccg ataaacatga tccacctaca ccaagccagt
     4441 tagtgccacc acttactttt tctaattctt tataattcat ttctttcatc ataaaagtta
     4501 cctccttttt tacaaatgtg atacacaaga aactgatccg ctaataatac ccacattagc
     4561 accaaatata gctccaccta ctgtaccaat tggagtacca aatgcagtgc ctgcaatgcc
     4621 atattttagt ccatccttca acgctcccat tccaatagct ttagcacaat ttgtgatttt
     4681 tctacggcgt cttgctttac caccgttacc accgaaaaca gctgacagtt cttcataagt
     4741 taaagtttca aatttgttca tgtttttccc ctttataaaa cttctaatta caattttcat
     4801 aagtgaatta agttttacct ctcttcaact tacacactaa taatacaaaa caatttacct
     4861 tcattggcgt ataataccga tttagcacga aacaagatct atttggaaaa tatttaccaa
     4921 atcggccaag ttttcgtata ttagtaattt acaaaggatt cttattaatt gttacgctaa
     4981 cttgatattc tgttttataa atccgaaaac tagtaaaaac atagacacaa tgcacttatt
     5041 atgagaatgg ctaacaaaaa aatcttctca tagccaaggc tacaagaaga ttgccatcac
     5101 attaatgcat aaactgatac gcacgctctt tactttaata aaacatgatc aattatacga
     5161 ctataacata gccactcaaa accaaaaact tgagtcgaaa tcaaatcatc atttttagca
     5221 tagtaaccta cgaaaaaaat cacaagtttc ataggtttct ttgcgttatc ttctaagtat
     5281 tacgatattt tctattggag atatttttag cctattcgca ccagtatttt tttcaatact
     5341 tatctactag ttattatcta cctctatgaa aagaactttg gaaaaactta ggattttcca
     5401 aataaacgtc tcgtttatga ttaccacctt tcttactgta taaaggtagc atgtgttcag
     5461 tatcagttag accaatatca tctacagaac ctgacccacc taaaattccg cttaaaagta
     5521 cttcatcttt agaaataatg attcgtttca tctacttttc ctccttagtt ttctttccta
     5581 atgaaatgcc caaaactaaa ctgattaaga tactaatcat tccaattaat tgaccccaga
     5641 tattatcctt ctcacctgta gatggtaaag actgagtaga accattttta atagtgtcat
     5701 tttccaatcg ctttaactta gtaattctat tttgattgtt cttaacggca ctataaggct
     5761 tgctttgcac ttttactgaa tcaaattgtt tattttcttt cacacttccg tgtttttcac
     5821 taactgctgc tagaataata ttctttttat gcgatttagc tgttttcttg accttagtgg
     5881 ctacgatttt aggttttact ggcttcttca cagttttctt cttagtttca gctctaggag
     5941 ccgcatactc ttgattacct gtcgtaactt tagtcagatc tgcagtagag ctagcaacat
     6001 ttgcagcatt ctcaaatacg ctattttcaa caaagtcagt aatagcaacg tcattgctag
     6061 actgtgtttg atcatcttca gctacagtca cttcaggtat ttcattactt tcagattcag
     6121 tagtattatc atccttcggt tgatccttaa ttactgcctg ttccactaat ttattagctg
     6181 catcagaata caaaaagtta tataactctt gtcccgtctt ttctccaccg acccatgcac
     6241 taataatttt tccattaata aatctcattg tagttggagt acctggaata ccaatttctt
     6301 tgaaggcata ctcatgtgct ccttcttcag catcaatatt gaaataaagc agcttacctt
     6361 taacgatttc attgaaatct tttaaatcag gtgaaaattg tcgacagtag taacatgttg
     6421 gacgaccgat atacataaga tgttcttgat tatttttctc tgctagaaga tcttttactt
     6481 cttgcatttt tactctatga aaatctttta cattgttctc ataatcttca acagatacct
     6541 catcttcatc atcttcacta tcttcctcat ttgcattatt aggatcttga ttattagtat
     6601 tctgtgactg attattttga tcttcagaag ctgctggctc ttcttcctgc ttattttgag
     6661 tttgagctgc ttcgttctta ctactagttt tctgctcaga ttcggaaaca tttttatcat
     6721 cattttctgt tttagatact acttcacttt tattctcttg agaagtatta ccttcatccg
     6781 catgcacaat agtactattc atcatcaata atactgctgg gctcaacatt aacattaata
     6841 tttttttctt attcatagat cttcctccgt attttttata actaagaaaa atatatcaat
     6901 tatcagctat ctttttggtt atcagactta ttcagtacac tttttgacca aatcagttat
     6961 caaaataatt ggaatttgat tctaactaaa aaagagcttt tcagctcctt ttaattttgg
     7021 ttaagaattt tatccttaaa atattcaaaa tatgtactct tacctgtaat aatagttgcg
     7081 ttgccttcca tcccatattt caaatttttc ttggacttgg ccttacagat tacttcatag
     7141 acattatttc cgcgtagatt aatgggatat actccaattt ctttcacttt tcctactaat
     7201 ctatccattg ttccactagc attagctacc tgaaaataca gtgtttggcc tttttttatt
     7261 gccccaattt tattacctgg gaaataagta actacattga ccgttctttt agccttaatc
     7321 atcggaaaca agtgaactgt attctcctgt ttatcatcaa gatgaactag ccatttttct
     7381 ctatttcttc taacaatttg tccttcatga tagtttctat tggcaatatt aagtgtattt
     7441 tgtggttcta caattccggt agatgtaact gtactttgtc tagttgcaaa gaaagaaccg
     7501 actattaaga tcagaactaa aattgccata ggaataataa tcatagttga aaaattcttg
     7561 aatttatagg aatagtattc ggtactctca tagtctttat tattcataac gttgctccta
     7621 attctcaact aagttatagt aaaagccatg tttctgcatt aatttctcat gacttccttg
     7681 ctcaacaatt tgaccatgat ctacaaccac aatattgtta gtcctttgtg caattgctaa
     7741 acgatgagca ataaaaataa tcgttttatc ttttaatttc attaaattat ctactacttt
     7801 tttctctgta atcgtatcaa gcccgctagt ggcttcatca aaaattaaaa ttttagccgg
     7861 tgacaataat gcacgtgcaa tagttagcct ttgcttttgc ccaccggata aaatcttggc
     7921 attttcatcc atcttggttt caaactgcag tggtaattgt tcgatttcag actcaatttc
     7981 tgctatctga caggctttca atatatcttt ttctgtaata tctggtcgac tacctaagag
     8041 cagattttct ttgattgttc ctgagaagat gtatggtgtt tggggaacat agtttacgta
     8101 tgaccgtaag acatgcttat ctactttagt agaattaaat ccattaaaag ttaacttgcc
     8161 tttgcttgga gagaagaaat caactaaaag tttgaccata gtagacttac ctgagccact
     8221 catccctacg attgccaact tatcattggg ttcgattttt aaattaatat cttttaatac
     8281 atcgactcca tagccataat gatagtcaac atgatgatat tcaatctcac ctgctaattg
     8341 cttggcatcc ctaatctgag catctttctg gaactcactc ttaaccatgt atacttcatt
     8401 caatcgattt tgtgctacat tagctgattg tagagttggt tgaagattaa taatgctctg
     8461 aagtggatct acaaaatacg atagtaatgc gttgaaggtc attaattgac caatgctcat
     8521 ctgcccgttc attacaacct tagcccctac ccagaggata attacattga gagataactg
     8581 aatgaaggtc tttaaagctg actgcaaaga ttcagtttta ctgtaacgaa aagatttctt
     8641 gaggtaatcg acgaattgac tatcaatctt acgataacgt gtttgttcgc tatttaaagc
     8701 tttgattgtt tcaattcctt gaatatcttc aattactgaa gaacttaaga cagcattact
     8761 ctccatctga tcattattca tcttttcaaa tttcttagaa aagctaagaa tcaccactgc
     8821 ataaattggc aaagacagta gagtaatcac aaatagagtg gaattttgaa ttgccaaaac
     8881 tattcccatc acaattacaa ttgaaagatc aagaaataat gaaataactg tactggcgag
     8941 tgcgtcaata attcgactag catcagagaa ccttgaggta atttcccctg ttctacgagt
     9001 tacgaagaat tccattggta attcaaaaat atggcgaatg tattgtaagt taagatcaat
     9061 acttaatcgc tgacctagaa catccaatag aaaattttgc ccgtaagaaa agatagagtt
     9121 gaaaacatat gctatcaata aaccaatagc taggatcgac aaagtttggt atgtaccgct
     9181 aggaatataa gtatcaatta agccttgcaa gaagtatgag ctacaaatac taatgattgt
     9241 catcaaaaga gcagccaaaa taatattagt gactagtttc ttttgtttga acatgtatgg
     9301 aaatagtgac cacagatttt gctttttctc tttgagtggc tcaaaatcat catttgggac
     9361 cataaaaagg gcaattcccg tccattcttg agaaaacttt tctttagaca ttttcgttaa
     9421 accaacgcta ggatccggat cagcaatcac taaataattt ttggttgcct taatcacaac
     9481 ataatagtgg agtaattcgc cttgctttaa gacgtgtacg atgaaaggat attgaatgtc
     9541 tgcatcagga tcaaacaagg acatgtcagc tttaactgct tcagttttta gattaaatgc
     9601 ttgtgctgtt ttaactaagc ccagagcggt agtcccttct aaattagtgc gggctgaatg
     9661 acgtaaatgg gctaaaaata ctctagaatg atatttttta agaatcatag ctaagcatgc
     9721 aactccacaa tctgattcgt ctacttgtgg tacataaatt gatttatact gtagtaacat
     9781 cttttccact cctcatatta agttgaatcc attatttcat gattggaaaa ctaaatgtaa
     9841 aaaaatacca aatcggttat tctcattacc gattcggtat tttagttttc taactagatt
     9901 gagctactca actttaatat tttcaaattt atctacaagc tttttaacca cggctttata
     9961 cgatctagaa taagttacca tctgaccatt atcaaatata ataatgcgtt ccttcgtgtc
    10021 aattgcacta atgttcttag gatttaccaa agaagattgc gaaacttttg ccaagaatgg
    10081 gttttcttta tcaatctgag taatatttgc cttatactca acttctccat tctcagtaac
    10141 catatgtact ttatgctgtg tagtactgtg ttcaatgaaa agtatatcgc cttcggccac
    10201 tttacatacg cgccgaccaa tcttataagt aaagtcacgt tgactaaact taattctgtt
    10261 agataaatta tcgaaggcgt tacataacgt ttcttcgata cgttgaataa tcttatcaga
    10321 cgacatagac ttactaatat aatcaattgc accgatacga cggcgatacg ttaatggagc
    10381 gtacttatcg tacgccgtta cgaagatgat ctgggcattt tcgtcattct tcttgatgaa
    10441 ttcagctaaa tctacgccat tcttagcttt agactctcga cttaattcaa tatctaagaa
    10501 gtagatacca ttcttaatat catttgtgac tatgtatcct accgcttgag caaaatcgtt
    10561 agcaacaaac gtaacagatt catttaattc agcgtaacct tcattatcat ctattaagtc
    10621 ttgaatagat gcattgatat tcttagccat ctgattagct aaatctttat cgtcatcgca
    10681 tacaatgatt gggaacttac tcatcctctt caccatcttc cgtatcaatt gtcatataaa
    10741 agtcgaacca gccgtcttga attgtataag aaatagacat atcaggatat ttactctcaa
    10801 tttccttaat attagctaat ccaagccctt tatggtcttt cttagtagta aagccacgtt
    10861 gttgaatttg actagttgag atatttttat tttggatttt atttctgatt tcgaactcaa
    10921 attcatctgg gtcatcagaa tagaccatta tttggacttc agcacttcga atatcatgct
    10981 tttcggcaat caatgcttta ctttcctcaa ttgcattatc gaaagtaatg ccaataatac
    11041 gtactagatc gagttcatct acatggtctg gtaaattacg gatattattt cgacattcaa
    11101 aattatatgg tatatccaaa ttatacaatt ctgttatctt tggaataata atgctcttaa
    11161 ttgatttaac gtaaatgtga tttaggtctt tatatttaag taaggcttta gaatttaggt
    11221 tagtttcagt atatttatct agtttctgaa ttacttcttg aacgttacct tcttgcgcac
    11281 ttacctttaa agaattaaga atatttttgt aatcatgtct gaaggcgcga agatcatctt
    11341 cacttttttc aagataagaa gcatattctt caagctgatg ctgctgttgc tttaattttt
    11401 cttgatcctt tttatttaaa agtttttctt gtaccatcgt catttcatga tatataaata
    11461 tagcaaaaat agtttggata agaatataga gagaaaagaa caaagttaat ggtgtaaaag
    11521 atttgctttg aatatatatg atagagatgc tcaccgtaga aacataggta taagctaata
    11581 tgcctacgaa aattttatta ttttggtttg ctagataatt atatattttt ccattaccta
    11641 gttttattgc aactatcatc attagtatta gtaagaaacg tagtgataat tggcctatca
    11701 aagtaaatga cataacctga gtgatcatat cagacacaat atcaactaat aaatctaatg
    11761 tgcatactaa tattattgaa ccaaatagta tttctaatgt attatttttt ctcaaatata
    11821 atacaaaaag caaagtttca agtatatttg tgaagattac gccaatatta cctatagaca
    11881 ataacaaccc taaaaaaata ttagcaatac acaaaaatag aatctgtctc tttttagatc
    11941 ttactcttga tattttaaaa aaacaccata catctgctaa actagaaaaa acattaagaa
    12001 aaagaaataa gactatcttt tccatatatt attccaaagt tttttactca agaaattaaa
    12061 accaacatgt gccgtgcttc caccaacaac cttagtcaat tcttcttcct tcaaaacagt
    12121 ctttttaaca ttttgcttct tcatgatatt tcatcctttc atgattttat actcaacttg
    12181 tttacacctt taatatatca tgtactttta agtaaattaa aaaagatacc aattcagtca
    12241 tactttcgta ccgatccggt ttcatatttc ttcaaacgta aacaactgac aattaatttt
    12301 cttagctaat tcctgacagc tatccgtaaa gccagatttg gaaaatagat aataatgctt
    12361 aagtggatac ttgaagattt cactatttgt aatcaatttt tctaacacac tacgagagat
    12421 cggttcattc ttccatttac attcgccgaa atatccatca cgttcatcgt cagagaatcc
    12481 tacaatatct aactcaactt gttgatgtgt tctcttatcg gttccccacc aattgcccaa
    12541 gtggataaac ggattaggaa caattttttc attcatatcc tgagaccaca tgaagtcttg
    12601 actgtatttt tcaaactcag gtcccatgaa atcagataga cccttttgta cttttaccca
    12661 agcaagatca gttaagccac gctcaattag atcggtttgc ttgccaacaa aggtatacca
    12721 gaagcggaac atcccgtcac agatacgata aacgatattt ttgcttttac tcttcttttg
    12781 ctcagtaacc ggtaactttt tctcaacaat acctaaatct atcaaattat tcaggtacgt
    12841 ggttagcgga ccagtttgta agtgggcgga ttgcgcaatt ttactatgct tagaagcacc
    12901 tgaagctatc gcattgataa tcgaattata gttagttgga tcgcgtaatt cctgttgtaa
    12961 caagttatta ggctcatcaa ataagcgacc tgatttactc aaaaagtttt tcttaatatt
    13021 atccgcaact gacatgctgt ctgacatata actcaaatat tggggtacac cgccacaaac
    13081 cgtattgatg ataaaagcgt cctctttact gagttttggt aacatttcat gtgcttctga
    13141 taatttaaat ggttcaagct ttaaggctaa agtgcgacga ccatatagtg gactttggta
    13201 gcctaagact tgtcgttcca taaatgacat cgatgaacca cataaaatca aaaataggtt
    13261 agtttctttg aattcatgat caatgtagga ttgcaacatt gaactaattg tagggtaagc
    13321 cttagccaaa taaggaaatt cgtcaataac taaaattaca cgttgttttt gagctaggtg
    13381 tgtaatttct ttaaagcatt cctcaaaatt tgcaaatttt tcttttccac cctgatctgt
    13441 atttttaaaa atactaattg catcagaaaa acgttttaga ttatcttccg cattttcttc
    13501 aagtgctaca taataaattg actttttatc ttttaaaaac tcattgatca gtgaagtctt
    13561 tccaattctt cttcgaccat agatcactgt aaattgaaaa tcattttctt gatacgcctg
    13621 attcaattgc tctaattctt gatgtctacc tacaaacat
//
