LOCUS       c00020_JAHHQA0..        5791 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAHHQA010000017.1 Lacticaseibacillus paracasei strain MYD3 17, whole
            genome shotgun sequence.
ACCESSION   JAHHQA010000017
VERSION     JAHHQA010000017
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-19 22:35:19
            Original ID  :: JAHHQA010000017.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5791
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5791
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[345:791]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      346..791
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..5791
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5791
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(13..210)
                     /locus_tag="ctg20_1"
                     /transl_table=11
                     /translation="MDKIISIIIVILILLATIAFYLAPFVGGLWQGAARSKVIAKILLL
                     NRDLKLSSKGLSRLINPQNP"
     CDS             complement(346..561)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_2"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.4e-09,
                     bitscore: 29.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISKEVGITLKQHDLVLIQGGAKRRNKPSGCIVSTIGGAVAGAAG
                     LNPFTTVAGAAIGLSLCLSTNYIHPA"
     CDS             complement(558..791)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_3"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 5.3e-15,
                     bitscore: 47.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYNYRQLDDFQLSGVSGGKKKFDCAATFVTGITAGIGSGTITGL
                     AGGPFGIIGGAVVGGNLGAVGSAIKCLGDGMQ"
     CDS             complement(1063..2016)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     223.7; E-value: 5.1e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_4"
                     /transl_table=11
                     /translation="MKQVRLGGSNWQASSVALGIMRMNVLAPDKAANVLDSAYNDGINF
                     IDSADIYGQGKSEEVFGEALKQASVSRDQLFIQSKVGIVVDPKRSHGSLVFGKRYDFSK
                     DHLLSAVDHILKRLQVDYLDSVLLHRPDPLMEVDDVAAAFDALEQSGKVRHFGVSNFNP
                     EQIALLESGIRQPLLIDQVQFSVAHTGMVNAGMHTNMADAASVDHDGSLLPYLQRKHMT
                     LQAWSPFQYGMFEGTFIDSPKFKALNDELQKVADHYHTNKNAIAVAWLLRHPVGVQVIL
                     GSMNPEHIKESAEGADITLTRQEWYDIYFAAGNDLP"
     CDS             2221..2955
                     /NRPS_PKS="Domain: PKS_KR (6-169). E-value: 3.6e-12. Score:
                     38.3. Matches aSDomain: nrpspksdomains_ctg20_5_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     192.9; E-value: 1.1e-58)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_5"
                     /sec_met_domain="adh_short (E-value: 1.1e-34, bitscore:
                     111.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LTVKDKVVVITGASSGIGAATVQVLAEAGAKLVIGARRTERLAEL
                     AASFTDGQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEW
                     ERMIDVNIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIM
                     DGLRQEQAANHIKTTMISPGAVNTELFSTITDPKRREAVEADEKNNGLSASDVAKAVLY
                     AIDQPANVAINEVLLRPVTQER"
     aSDomain        2239..2727
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg20_5_PKS_KR.1"
                     /evalue="3.60E-12"
                     /label="ctg20_5_PKS_KR.1"
                     /locus_tag="ctg20_5"
                     /protein_end="169"
                     /protein_start="6"
                     /score="38.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVITGASSGIGAATVQVLAEAGAKLVIGARRTERLAELAASFTD
                     GQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEWERMIDV
                     NIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIMDGLRQE
                     "
     aSModule        2239..2727
                     /domains="nrpspksdomains_ctg20_5_PKS_KR.1"
                     /incomplete
                     /locus_tags="ctg20_5"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       2242..2322
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg20_5_0001"
                     /evalue="1.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg20_5"
                     /protein_end="34"
                     /protein_start="7"
                     /score="14.1"
                     /tool="antismash"
                     /translation="VVITGASSGIGAATVQVLAEAGAKLVI"
     CDS             2981..4144
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217:NADH:flavin oxidoreductase/NADH oxidase (Score:
                     286.7; E-value: 3.8e-87)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_6"
                     /transl_table=11
                     /translation="MSGYHFLKPFTFKHQTITLKNRIVIPPMTTRLSFEDGTVTRDEIR
                     YYQQRAGGVGMFITGTANVNALGKGFEGELSVADDRFIPGLSKLAAAMKTGGTKAILQI
                     FSAGRMSNSKILRGEQPVSATAVAAPRAGYETPRALTSAEIEATIHDFGQAVRRAILAG
                     FDGIELHGANTYLIQQFYSPNSNRRTDEWGGDRDKRMRFPLAVVHEAEKVIATIADRPF
                     LLGYRISPEELEQPGITLDDTLALIDTLKQTKIDYLHVSQSDVWRTSLRNPEDTAIMNE
                     QIRDHVAGAFPVIVVGGLKTPADAEKAADSFDLVAIGHEMIREPHWVQKVLDHDEKAIR
                     YQIAPADLEELGIAPTFLDFIESISGGAKGVPLTTAQSVTSSNVTQD"
     CDS             complement(4406..5782)
                     /locus_tag="ctg20_7"
                     /transl_table=11
                     /translation="MSKYRTETDTLGPVEIPANALWGPQTERSRHNFQAGPLMPMPVIR
                     ALLQLKKAAARANVAADVLPAPKGQLITRAVDALLALPDEKLQKDFPLHVYQTGSGTQT
                     NMNVNEVISHQAAKLNPDLPILPNDDVNHSQSSNDTFPTVMNITAAIAVNQLLHAVNQL
                     CSVLYSKAVTYARVVKIGRTHLQDATPLTFGQEISGWVAMMEHDQIALKQLQPNLFYLA
                     IGGTAVGTGLNADPNFGKIVAGRLSDVYQLPLSAKTNKFAALAAHSEISVVHGAIKTLA
                     ADLLKIANDIRFLASGPRAGYGELRIPANEPGSSIMPGKVNPTQAEALTMAAVRVMGND
                     TTITVAASQGNFELNVYKPVIISTFLESADLLTKTVTSFTEKLAAGLTIHAPHMRALVD
                     HSLMLVTALAPHIGYEKSAAIAQLAEQENLDLKAAAVKSGDVTAAQFDKWVDPLKMTRA
                     "
ORIGIN
        1 actagacagg ttctaagggt tctggggatt gattaaccta ctcagcccct tactagatag
       61 tttcaaatct cgatttaaca aaagtatctt ggcaatgact ttgcttcttg ctgccccttg
      121 ccaaagtcct ccaacaaatg gtgctagata aaaagcgatc gtcgccagta aaatcaagat
      181 aactatgatg atacttatta tcttatccat ttgtatttcc tcttcctttt gcacaaatag
      241 actaatttga aatcgatctt tgactaagac aagaaaaagt gagcactacc aaggtgttag
      301 ttatattgaa cagttgcgat aggagctaac cgtctttgtc caatattagg ctgggtgaat
      361 gtaattagtg ctgagacaca aggataatcc tattgcagcg cctgcaacag ttgtaaatgg
      421 atttaatcca gctgcccctg ctaccgctcc cccgatcgtg gacacaatac acccactagg
      481 tttattgcgt cgcttggctc ctccttggat taagaccaaa tcatgctgtt ttaaagtaat
      541 gcccacttct ttacttatca ttgcatccca tctcctaagc atttaatagc tgacccaacc
      601 gctcctaagt ttccaccaac tacggcgccg ccgattatcc caaaaggacc accagctagg
      661 ccagtaatcg ttcctgatcc aataccagcc gtgatgccag taacaaatgt agcagcacaa
      721 tcaaatttct ttttcccacc tgaaacccct gacaactgaa aatcgtcgag ctggcgataa
      781 ttataagaca taattttcct tttttcttca aaaagcaaca agttattttg tgtaaggtcg
      841 actttactgt ctttaacata cattaattat ttgtgtaaaa tgccaaaatt ttttaaacgt
      901 aggaaatttc cagtttaacg tcgtctttac acttttattg ttcagttgcg ctttaaaagt
      961 caaaaattct taacgtttaa atctccttgc ttggtaaaaa cttcaatttt ttgcaaaaaa
     1021 aatcgtctca gcaatttgag acaatttttt catatcatca acttacggca aatcattccc
     1081 cgccgcaaag taaatgtcat accattcctg tcgggtcaac gtgatgtccg cgccttccgc
     1141 actttccttg atatgttcag gattcataga gccgagaatc acttgcacac cgactggatg
     1201 gcgtaatagc caagcgactg cgattgcatt tttattggtg tggtagtggt cagcgacttt
     1261 ctgcagttca tcattcaacg ccttaaattt cgggctatcg atgaaggtac cttcaaacat
     1321 gccgtattgg aatggcgacc atgcttgtaa ggtcatgtgt ttgcgttgca agtatggtaa
     1381 taggctgcca tcatgatcga ccgaggcagc gtcggccatg ttggtgtgca tccccgcatt
     1441 gaccatgcca gtatgggcaa cggagaattg aacttggtca atcagcaaag gctgccgaat
     1501 gccgctttca agcaacgcaa tttgttcagg gttaaagttg gagacgccaa aatgccgaac
     1561 cttgccactt tgttccaatg catcaaaggc cgccgcaacg tcatcgactt ccattaacgg
     1621 atctggccga tgcagcaaga ccgaatcaag gtaatcaacc tgcaaccgtt tcaaaatgtg
     1681 atcaaccgct gacagtaagt gatcttttga aaagtcgtac cgtttgccga ataccaaact
     1741 gccatgagag cgttttggat caacgacgat cccgactttc gattgaatga ataactggtc
     1801 gcgggaaacg ctggcttgct tcaaggcttc accaaaaact tcttcggatt tgccttggcc
     1861 ataaatgtcg gccgagtcga taaagttgat gccgtcattg tacgcactat ccagcacatt
     1921 ggccgctttg tcgggggcca gcacattcat ccgcatgatg cccaaggcca cacttgacgc
     1981 ctgccaattg gatccgccta atcgaacttg tttcataaac acaaaactcc cttcgatacg
     2041 tcatttcaaa ttatgttact gacgacaagt taagtgtagc ccctaaagtc cacttgaggt
     2101 caagccaata ttagaatttc aataaaacag cttgcatggt gctgagctgc gcggtaggtt
     2161 aagctgtgtc tgttacttat tttttcttag caggataagc ccataaagga ggccgtgatt
     2221 ttgacagtta aagataaagt ggttgtaatc acaggtgcat cgagcgggat tggcgcggca
     2281 acggtacaag tgttggccga ggctggtgca aaactagtca tcggtgcgcg gcgcacagaa
     2341 cggttggctg aattggcggc cagctttacg gacggtcagg tgctgtatca acaaaccgat
     2401 gtgaccgacc agcagcaagt gaaagcgctg attgatttgg cgttggataa gtttggtcat
     2461 gtggatgttt tgtataacaa cgctggcctg atgccacttt ctgaaatggc cgaactcaaa
     2521 gtcaacgaat gggaacgtat gattgacgtc aacattaaag gcgtcttgta tgggatcgcc
     2581 gcggttttac cgcctatgat tgcccaacac agtggccaaa ttatcacaac agactcagtt
     2641 gccggtcaca ttgttcaccc tggaaccgcc gtttactccg gtaccaagtg ggctattcag
     2701 gcgatcatgg acggcctgcg acaagaacaa gcggctaatc atattaaaac gaccatgatc
     2761 tcgcccggtg ccgtgaatac tgagcttttc agcacaatta ccgatcctaa gcgccgtgaa
     2821 gctgttgaag ccgatgaaaa aaacaatggc ctcagcgcct cggatgttgc caaggcagtt
     2881 ttgtatgcca ttgatcaacc ggccaatgtt gccatcaatg aagtgctctt acggccagtc
     2941 acgcaagaac gttaattttc gtctaaagga gtgtgattgc atgtcgggtt atcatttttt
     3001 aaaaccgttc accttcaagc accaaaccat cacgttgaaa aatcgcattg tcattccgcc
     3061 gatgacaacg cgcctgtcgt ttgaagacgg cactgtgacg cgggacgaaa tcaggtatta
     3121 ccagcaacgg gccggtggcg tcggcatgtt tattaccggt accgccaatg tcaatgcgct
     3181 tggcaaagga ttcgaaggtg agctaagtgt cgctgatgat cgattcatcc ccggtttgag
     3241 caaactcgcc gctgcgatga aaacaggcgg caccaaggct attttgcaaa tcttcagcgc
     3301 tggccgcatg agcaatagca agattctgcg cggtgagcag ccagtcagtg ccactgcggt
     3361 tgctgcgcca cgggcgggtt acgaaacacc gcgcgcattg acatcggcag aaatcgaggc
     3421 cactattcac gattttggtc aggctgtgcg ccgcgccatc cttgctggtt ttgatggcat
     3481 cgaactgcat ggtgccaaca cctatctgat acagcaattc tattcgccaa actctaatcg
     3541 ccgaaccgat gaatggggcg gtgaccgcga taagcggatg cgttttccgt tggcagtcgt
     3601 tcatgaagca gaaaaagtga ttgccacaat tgctgaccgg ccatttttgt taggctaccg
     3661 catttcgccg gaagagttgg aacagcctgg cattaccttg gatgatacct tggccttaat
     3721 cgacactttg aaacaaacca agattgatta cctgcatgtc tcccaaagtg acgtttggcg
     3781 aacctcattg cgcaaccctg aggacacagc catcatgaat gaacaaattc gtgaccacgt
     3841 cgccggtgct tttccagtga ttgtggtcgg tggtctgaaa acgccagccg atgctgagaa
     3901 agcggctgat tcctttgact tggtcgccat tggtcacgaa atgattcgcg agccgcactg
     3961 ggttcagaag gtcttagacc atgacgaaaa ggcgatccgt taccagatcg cccctgctga
     4021 tcttgaagaa cttggcattg cgccgacctt cctcgatttt atcgaaagta tttccggtgg
     4081 ggcaaaaggt gtcccgttaa caactgcgca gtctgtgaca tcaagcaacg tgactcaaga
     4141 ttaatctagc atttcaaatc atcgtgcgag tcgagctgta aaaagctcgg cttttttctt
     4201 gccgtcttca acttacgcga tggtgcctgg agctaccagt gatttataag ttttaaatca
     4261 aggtgtgatc atcacctgct cacgctctga cttaaacgcg ttcaccagcg cagaaaccta
     4321 cacataagga cctgaaacct aaatggtcaa agcccgacca tttaggtttc aggccactta
     4381 tgttccggtt tctaaccgcg ccagctcacg ctcttgtcat ttttaacggg tcgacccatt
     4441 tatcaaactg cgctgctgtg acgtcgccgc ttttgacggc ggctgctttt aaatcgaggt
     4501 tttcttgctc agccaattgc gcgatggcgg cacttttttc gtagccgatg tggggtgcga
     4561 gggcggtgac cagcatgagc gaatgatcaa cgagtgctct catatgcggt gcgtggatgg
     4621 tcaagccggc agctaatttt tcagtgaaac tcgtgactgt tttggttagt agatcagctg
     4681 actctaaaaa ggtactgatg ataaccggct tgtagacgtt caattcaaaa ttgccttgtg
     4741 acgcggccac cgtgatcgtc gtatcgttgc ccatgactcg aacagcggcc atggttagcg
     4801 cttcggcctg tgtgggattc actttgcccg gcatgatgga actaccaggc tcattggccg
     4861 gaatgcgcaa ctcgccgtat ccagcacgtg gaccactggc aaggaagcga atgtcattgg
     4921 cgattttaag cagatccgcc gctagcgttt taatggcacc atgaacaacg ctaatttctg
     4981 agtgtgccgc taaagcagca aacttattgg ttttcgccga aagtggtaat tgataaacat
     5041 cgctcaatcg gcccgccaca atcttgccaa aattagggtc agcgttaagc cccgttccga
     5101 ctgctgttcc gccaatggct aagtaaaaaa gattgggctg aagctgcttt aaagcaatct
     5161 gatcatgctc catcatggcc acccatccgc tgatttcttg gccaaacgtt agcggcgttg
     5221 catcctgtaa atgagttcga ccgattttaa caacacgagc gtaagtgacg gcttttgaat
     5281 ataaaacact gcacagttgg ttgacagcgt gcagcaactg attcactgca atagccgccg
     5341 taatattcat cacagttgga aaagtatcat tggagctttg actgtgattc acatcatcat
     5401 tcggtaagat cggcaagtcg gggttgagtt ttgcagcttg gtggctaatg acttcgttca
     5461 cattcatatt tgtttgtgtg ccagacccgg tttgatagac atgcagtgga aaatcttttt
     5521 gcagtttttc gtctggcaag gccaacaagg catcgactgc tcgcgtgatt aattggcctt
     5581 ttggtgccgg taaaacatca gcggccacat ttgctcgcgc tgccgctttt ttgagttgca
     5641 gcaaggccct aatcactggc atcggcatca atggaccagc ctgaaaatta tgccggctgc
     5701 gctctgtttg cggtccccac aaagcgtttg ccggaatttc aactggtcct aatgtgtccg
     5761 tttctgttcg atatttgctc atgtttacct c
//
