LOCUS       c00016_JAHOCU0..       20129 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAHOCU010000024.1 Bifidobacterium breve strain MSK.22.34
            NODE_24_length_36857_cov_329.106, whole genome shotgun sequence.
ACCESSION   JAHOCU010000024
VERSION     JAHOCU010000024
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 03:08:24
            Original ID  :: JAHOCU010000024.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 20129
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..192
                     /locus_tag="ctg16_1"
                     /transl_table=11
                     /translation="AVPASGTRTRTNARTAAAYRPYRVSKARSSPEATRASRSPSRVAA
                     PPGEVMSSCVCGSFHSTS"
     protocluster    1..20129
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9856:10129](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(9857..10129)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..20129
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /kind="neighbouring"
                     /product="RRE-containing"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..20129
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03882))"
                     /tool="antismash"
     protocluster    1..15152
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2162:5152]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      2163..5152
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="2"
     cand_cluster    1..15152
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="2"
                     /tool="antismash"
     CDS             complement(270..1283)
                     /locus_tag="ctg16_2"
                     /transl_table=11
                     /translation="MLYLSAFTVPFLFALALWPVVSVALTVPVLAMLYHRDNRLGLPAI
                     LSAYGTVLYAIGLLCLTLYPLPADPVAFCAVHHLKPQLDLFRFVADIRTDGLDAVLQIV
                     MNVVFFLPLGFIVRRVFHRGLPTATVAGFLVSLLVETMQLTGTLGVFPCAYRLFDVDDL
                     VWNTSGALAGYGCALAFDRLLPMRESDAATVTHPGLVRRLVAFLVDMGLVMSAALPLAV
                     AANVIHALVSGVRPGAAADRVLGGLGFSGLMFLLMLFVFEVLVPWLRDGRTLGGGYTHM
                     TCETVPRSGVRRILFYMARFVVFACLALAGIPWQPVIALALLTFWMAFRRMPYDLI"
     CDS             complement(1285..2154)
                     /locus_tag="ctg16_3"
                     /transl_table=11
                     /translation="LISINVEIFKKELLKNLNAQIDYFSPLFWINDSERKQFPWGPLVE
                     LLQIINTLTEEDILKYFDLDKLAIIGRELWNHRFPFNPYILLGRSILSDLCIRNNKTRI
                     LWADIRNNDTIRATEEPLLWCQIPQLERDYLAECLQKKDSSLLYKSSLISYLKARSEGR
                     LNDRVSAYYLTHLIIYCTNYGKRNFFPLHVRDILFQDAQAVAKESFSKKNYDLLAEAEA
                     SKCALGLHDQHTLKYAMYLFGLFSRYRCIPCFEIEDFTSLSKKDKFRLSYHTMLASSLL
                     VSILSRQE"
     CDS             complement(2163..3521)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     288.9; E-value: 1e-87)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_4"
                     /sec_met_domain="LANC_like (E-value: 1.2e-41, bitscore:
                     134.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKQDQSKFLPPEIEKQFFYIIDELCHRLIDPKQLKSIVDQPGNH
                     EPLFDTSVWAPCTISHGLCGTSIFYSILANKYESFRAVAHNHLLLATSTINWCINGGVM
                     GGPSGLLAAAQIASRSPMDYSKLREQLTAWICRCQLYLINRYRSSLGNGVPWLAYDIMN
                     GICGNLRILLDENSTNARETINLSVKYLCDLVLTSNSQGMPGWWVPGNLQPTKQDENEY
                     PDGDLNVGVAHGAAGILGTLVSVFNYGYTDTRVMDSIKRIMEWTFHWTQHADDFDYWPA
                     RIPTNCQIQDDVLSPLPTRAGWCYGTPGIAVEMLRASTLLDDVDTTGHIIDILSSHLSS
                     PTNQWHIAGPTFCHGYAGVLYSVFKAWTLCGSEVLRNIGSNMANNLLAMADECSPFVYQ
                     HWMYSNTPSHKINLKKLDNVGLLEGSSGIGLVLYSICNQGDSSANWDRVFALS"
     CDS             complement(3527..5152)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     316.3; E-value: 6e-96)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_5"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.6e-40, bitscore:
                     130.2, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 9.3e-18, bitscore:
                     56.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLLPKYVEKQFLNPIFEPDEYSAVINYPTRSDAAANLIDTPIAG
                     ERIISVNIPEENNEHCISLSQIGIRANKEGLYAVDLYTGQKIRIRAHNTVYPPAQAPNE
                     VRLLIEIMNEGARLWNPWSWNSLDSFPYRPRVRYGHIILSSRSWRLDELRESELASCKH
                     WREKWNVPRYCLAVSQDMRLLLDLDNPLHQTLLINESRKDKQLLVQEIPAGGNNPDAVW
                     GWMRKDGQSICSEIVFNFHKIDHKFSNSSTSMIPYRKIISRNNHIFLPGNENWLSCRIY
                     MPPENMVNYLKNNLTDILDCFNSSTVKHSFFVRYADRQGTHLRIRINGNDTDFNRLTSI
                     LVKSIVDGDARTYDFNEYIPEVNRYGGIQMMELTHQCFTTDSMNALQQIDKKGMEYDLD
                     SLAALCVMLTGFGNGYAKSKSFDLQEGKRWADYLNLSTSHDKEYQKNRKIWIESIKSVI
                     LHESKQVSKLDDLYKAYRDLGYMMKKSCNNYTATSSPTRVIGSHLHMCLNRRYGPNPEI
                     EDRLLRIAQSVLTSINQSIKYGEF"
     CDS             complement(5386..5631)
                     /locus_tag="ctg16_6"
                     /transl_table=11
                     /translation="MLNWQFIYRKYSRKIVKACPHCNIIIMNLLNNMGLMKRFQFSILQ
                     IPQKELVCQMTINIPNIQIRLALAQIIISMRSMNIT"
     CDS             5925..6110
                     /locus_tag="ctg16_7"
                     /transl_table=11
                     /translation="LTRRLIKLREVSSSTLNCLDSRSRMVLTLMSLSFNRSSIMGVHLM
                     STRLLHILSLLTVYSM"
     CDS             complement(6704..6880)
                     /gene="allorf_06704_06880"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_06704_06880"
                     /protein_id="allorf_06704_06880"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MNTAILEKPTVDVMDIDLDIDVEDLPVEQIDQIRLTSISLCTPGC
                     TSPNGGSGCSFCC"
     CDS_motif       complement(6785..6880)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MNTAILEKPTVDVMDIDLDIDVEDLPVEQIDQ"
                     /locus_tag="allorf_06704_06880"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(6704..6784)
                     /prepeptide="core"
                     /locus_tag="allorf_06704_06880"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-10.80"
                     /molecular_weight="2420.8"
                     /monoisotopic_mass="2419.1"
                     /core_sequence="IRLTSISLCTPGCTSPNGGSGCSFCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNTAILEKPTVDVMDIDLDIDVEDLPVEQIDQ"
                     /leader_location="[6784:6880](-)"
                     /alternative_weights="2438.8"
                     /alternative_weights="2456.8"
                     /alternative_weights="2474.9"
     CDS             complement(7663..9306)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 286.4; E-value:
                     7.9e-87)"
                     /gene_kind="transport"
                     /locus_tag="ctg16_8"
                     /transl_table=11
                     /translation="MTLLLPKYMTNFFQNGVFQVPQWPVIAGMLLLVTASGAISALQNY
                     QLQSTGEDIVRDARLALSKHLLRLPIREYDQRDSGDLLSRVSNDTSQLRNAFMQCTSAL
                     ASGFITVIGSAAFMAMLDPILFGTAITLLLTVFTLMLLSAKFIERASYDSQYTLGDLTS
                     TLNRDLAGIRTIRASNGFENENKVIAALINHVRLSGLKIARIQSIVNPLATIALQLAAI
                     IVFGLGLWRVTTGLLSVEKLTQFIMLLFISISPLSQIIYAGSQIGNSMAAMNRIREILD
                     IPEEKDPDTVVTTINEHMPLAHSSPCPPAVEFQHVYFSYESKPILHDLNLSISQGSVTA
                     LVGPSGAGKSTILQLIERFYDPSSGNINVLGKDITTCDRDDLRSHIAYVEQDSPALSGS
                     IRENLLLGSNDCSDDECRRALKSVNLSHLLDRSDKGLDMQIGENGIMLSGGERQRLAIA
                     RALLSTAKIILLDEATANLDADNERLITRLLAQVEGRTFIIVAHRLATIIDSDLIYVIN
                     HGRVIGSGTHKQLFENIPLYHNLATKQHIA"
     CDS             complement(9857..10129)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_9"
                     /sec_met_domain="PF05402 (E-value: 2.6e-11, bitscore: 35.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.7e-16,
                     bitscore: 50.9, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQADDTQTSISLRNQISLYPKEGGAIVFVNDTGEYLQVNEIGRII
                     LDGLMCGKTVEDCTNKIAEEYQADRQIIARDADRFLADMGKHVRL"
     CDS             complement(10116..10604)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_10"
                     /sec_met_domain="Asn_synthase (E-value: 2.1e-17, bitscore:
                     55.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKHADIRPLNPDRSRHQALYSLSMQARMLNQVNRTFASNDITFRS
                     PYLDHGIADYALCAPISARTEGNLHKAVLYRALKGIIPETIFRRPVKGDHSYSLYLAWQ
                     RSKDALLDSIAGGVLDEEGLIDMPAIRRRASMPMPDITFLFEMQRVAAVERWLRYASR"
     CDS             11197..11811
                     /locus_tag="ctg16_11"
                     /transl_table=11
                     /translation="MAAESTPPDTSADSGASLRHSSAIVRKRLLSDAKISLLGTCFAGE
                     GSALVYRGLLDLSRCSMVAAGMECMFLHGDLSPRRLSGSEGSKSMTMRSRSRSAFVMLA
                     SREALSDRSTSSSETVQNTRSPLSRGTWTHVPSSLMLMEAGSFEQFVGFPPRTITVRFG
                     FLCVNGITFPYPDTARDHQYMQGFGQFDPQGNGALAPPTST"
     CDS             complement(11760..12011)
                     /locus_tag="ctg16_12"
                     /transl_table=11
                     /translation="LSSEDDKHQTHSWMYHPNQVNWNGMHRHAIRSHIQSMRRTKMKDY
                     VPPAVEVIASFKEATNGVWFGNYVDVGGAKAPFPWGSN"
     CDS             complement(12060..12377)
                     /locus_tag="ctg16_13"
                     /transl_table=11
                     /translation="MTELQNLLTVKLHALAPIGVLKMRFAIALLPNPKALIMDEPLQTL
                     DRSGTNWICEQIRKQANRGVAVLIASEPDSRLRPITDDVVVLDKGTVVKEGSRGQLWKE
                     D"
     CDS             complement(12989..13696)
                     /gene_functions="regulatory (smcogs) SMCOG1016:LuxR family
                     DNA-binding response regulator (Score: 168.2; E-value:
                     2.4e-51)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg16_14"
                     /transl_table=11
                     /translation="MKDARDDIIKVMLVDDMRGARTGFMMMLNNDPNIIVSSQAADGAQ
                     AIEFLRQSPQQLPDVILMDVRMPVMDGIEATGIIKEQFPQIQILILTTYDEDDYAFDGL
                     ARGASGFLLKDATPKQLRDAVHAVHNGDAVLTPRITGEVLNRGVRPISDNTRIKLLRSL
                     FDGLSKREYEVAELVAAGLSNQEIAEHLFIETASVRRTVSRILARMHMRDRVQIAIAWY
                     QSGLDQITGGKPA"
     CDS             complement(13713..14603)
                     /gene_functions="regulatory (smcogs) SMCOG1048:sensor
                     histidine kinase (Score: 102.2; E-value: 5.6e-31)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg16_15"
                     /transl_table=11
                     /translation="MCDLAMICMIAMQYMHPASLQPQYLALLYSVALAGIASSLLSIAR
                     DRRTANRLLSEARRKAAILAEEKNRTERRLRMANELHDSVGHGLTSIIALSQGGEDCIR
                     NGGYSDSQLADALAEITSIAKDSLGDTRRILKVFNEEESQPSLEQVGLEPVNQDDILRL
                     RDWDDIRPVLEHIRSTGIIVVFTETGRRVEDPRRSDLCFAVTREALTNALRHGAGLTRI
                     AVSWNHYRDGGTAITIRNDGHVSGHGTTGEASGQSGKPTGGTGLQRLSQRLAKMGGTLS
                     YGPYGNGWAVKALIP"
     CDS             14713..14874
                     /locus_tag="ctg16_16"
                     /transl_table=11
                     /translation="MNSKASNATGLLNLNVTFMAPKTSSMRKYHIPAPSLRNRINEYPV
                     PIAIRSST"
     CDS             15162..16175
                     /locus_tag="ctg16_17"
                     /transl_table=11
                     /translation="MTVAYRGLPAPLAERMLQAGLFDILSAIGAGTRPRAMRYAHDHVV
                     WPLACSRRWAARNLTRGLRPPPACHALRLRSLRRVPRRSRACAATANQHAVFATARIVA
                     VHASGLSAYAHGRRVVSEMETTRKGPMDMNDMVDTRTTGTGLAKRVRDGFLQDRRELGP
                     AQAADKWFAPLMDRWNGLLSRDEGGFSHEERVTLAVLMTEYLSMRDALILASLHEMGGG
                     ELHMLYAKPHSMESAAVVMRELSRAFKDADYQPDTRRGERATALLESVTADAPDGYEAQ
                     PMASCAYLLWMADRSTAAAVRALKALALDDDCSLASLVLAASEHGIRPAWTERRRH"
     CDS             16265..17824
                     /locus_tag="ctg16_18"
                     /transl_table=11
                     /translation="METAIIERPVMADEGMDESNIVMLDVGLIDPNPANPRRDVGDVSE
                     LADSIRAQGIRQNLLVTPTLQGRYLLVIGHRRLAAAKLAGLSRVPAVVADLSEREQREL
                     MLVENSQRADLTVIEEADGYQGLLDLGVGVDEAAQRTGRSVSLVRRRLKIAAIGENARS
                     KAGTAQLSIDDWETIADFDRYPDLQERLAEAAGGKNWNMAVKHARQERTWREWLDTARA
                     ELERMGIDAADEQPNTDNWYDSPKGLRRTTMLTTGDIAKAIDAWRDSHDGATPVVGVRA
                     EGASWARGIVLYETVDEEAETAAREAREARWREEREREERETAPAKEFARASRDLRIAF
                     VTHLMELKSQPKGIGRAVALLSARFALDALTEGFDQWDGHAEDVWEQITGIDTTGDDAD
                     AEEPEGETEDPLRASVTAMIAGDPQRAAFGLLYALAEERVSWETWRGAATIAEHAAPLY
                     EALETLGYRTSDTETEALNGSLAPIDDNDNGGDAGIRQDGEPDDDGTSQTDDASGKPED
                     AE"
     CDS             complement(17940..18362)
                     /locus_tag="ctg16_19"
                     /transl_table=11
                     /translation="LDWTRRGCDSVSRVLAATLDDIGDIREVTAMPMLLVMLGLSLATG
                     VIRMLMRGVASCLALLAHPLRLVVFLANSVFTAFAMLSGLLMLAFLLMHFLAGSDAPAL
                     DGSFALIVAAFLTAVLASMLMDWCDARLRRRSARHG"
     CDS             complement(18301..18807)
                     /locus_tag="ctg16_20"
                     /transl_table=11
                     /translation="MAKPRERNRAMRAIADNALDAELEALRRKRGELSRLGILLDDMRW
                     AAERFRDAAQSFCDDHHMPRAQLVRTLRMEPRETGMAFHAVTPDYGQANPADSHGEIHD
                     GEDSAVESGGRPASAADAPETALTEDNAATENAADAVDAGTSGSIGLDPEGLRFGFPRP
                     GGYAG"
     CDS             19096..19500
                     /locus_tag="ctg16_21"
                     /transl_table=11
                     /translation="MGWKGNRSRTIRKAVTFSEEEWRWVADSLKVENRQRIQAGLRPVG
                     WMTFARNRIRCAHRVNITVPANLHDVSAQLARIGNNVNQIARHANTTRETDLAMLSRVF
                     DELRQAERLVAGLSIRVETDVDPKGVPEWL"
ORIGIN
        1 gccgtgccgg catccggcac gcgcacgcgc acgaacgccc gcaccgccgc agcgtaccgc
       61 ccatacaggg tctcgaaggc acgctcgtcc ccggaggcga cccgcgcgag cagatccccg
      121 tcacgcgtcg ccgccccacc gggcgaggtc atgtcatcct gcgtatgcgg ctccttccac
      181 agcacatcgt agacggatgt tcatcggtat atgtagcggg gaacgcgccg gcggttcatg
      241 gcacgtgcat cgacatgccc ggaggggcgt cagatcaggt cgtagggcat gcgcctgaac
      301 gccatccaga acgtcaggag cgcaagggcg atcacgggct gccaaggtat gccggcaagc
      361 gccaaacagg cgaacaccac gaaccgtgcc atatagaaca ggatccgacg tacgcccgag
      421 cgcggaaccg tctcacaggt catatgcgtg tagccgcctc ccaacgtgcg cccatcccgc
      481 agccagggca ccaacacctc gaagacgaac agcatgagca ggaacatcag ccccgagaac
      541 cctaacccgc ccaacacgcg gtcggcagcc gcaccgggcc ggacgcctga gaccaatgcg
      601 tggatgacat tcgccgcgac ggccaacggc agtgccgccg acatcacgag gcccatgtcc
      661 acgaggaacg cgaccagacg ccggaccagg ccgggatggg tcaccgtcgc cgcatccgac
      721 tcacgcatgg gcaggagccg gtcgaatgcc agcgcgcacc cgtacccggc cagcgcgccc
      781 gacgtgttcc acaccagatc atccacgtcg aacaggcgat acgcgcacgg gaacacgccc
      841 aacgttcccg tcaactgcat cgtctccacc agcagcgaga ccaggaaccc ggcgacggtg
      901 gccgtgggaa gcccgcgatg gaacacacgc ctgacgatga acccgagcgg cagaaagaac
      961 acgacgttca tcacgatctg caacacagca tccaacccgt cggtacgtat gtcggcgacg
     1021 aaccggaaca ggtccaactg cggcttcaga tggtggacgg cgcagaacgc gacgggatcg
     1081 gccggcaacg ggtacaaagt gaggcacaac aagccgattg catacagcac cgtgccatac
     1141 gcggacagga tcgccggcaa tccaagccgg ttatcgcggt gatacagcat cgccagcacc
     1201 ggaacggtca acgccacgga caccaccggc cacaacgcca acgcaaacag gaacggaacc
     1261 gtaaacgccg ataaataaag catatcattc ctgtcttgat agtattgaga ccaataagga
     1321 cgacgcaagc attgtgtgat atgacaagcg gaatttatcc tttttagaaa gagaagtaaa
     1381 atcttcgatt tcgaaacatg gaatgcacct ataccgactg aataatccaa ataagtacat
     1441 agcgtatttc aaggtgtgtt ggtcatgtaa tcccaaggcg cattttgatg cctctgcttc
     1501 cgcaagcaga tcgtaatttt ttttggaaaa agattctttt gccactgctt gggcatcctg
     1561 gaaaaggata tcccttacgt gcaatgggaa aaaattcctt ttcccgtaat ttgtgcagta
     1621 tattattaaa tgtgtcaaat agtatgcact gactctgtcg tttaatctac cttccgatct
     1681 tgctttcaga tatgaaatca gtgacgattt gtataataaa gatgaatcct tcttttgcaa
     1741 acattccgcg aggtaatcac gctcaagctg aggaatttgg caccataaca agggttcttc
     1801 cgtagctctg atggtgtcat tgttccggat gtcagcccag agaatgcggg ttttattgtt
     1861 acggatgcac agatcggaaa gaatgcttct tcccagtagg atgtaaggat tgaaggggaa
     1921 tcggtgattc caaagctcac gtcctataat ggctaattta tctaaatcga aatattttaa
     1981 tatgtcttcc tctgtaagag tgttaatgat ttggagtaat tcgaccagag gtccccatgg
     2041 gaactgtttc ctttctgaat catttatcca gaacagcggt gaaaaataat caatttgtgc
     2101 attaagattt ttgagtaatt cttttttgaa aatctcgaca tttatgctaa tcaatattgg
     2161 tcctaagata aagcgaaaac gcgatcccag tttgcagatg aatcaccttg attgcatatt
     2221 gaatacaaaa ccaagccaat tcctgaagaa ccctctaata aaccaacatt atctagtttt
     2281 ttcaaattaa ttttatgcga gggtgtattg gaatacatcc agtgttggta tacgaaagga
     2341 gaacattcat cagccatggc taataaatta ttagccatgt tcgaccctat attccgtagt
     2401 acttcacttc cgcaaagtgt ccaagcctta aatacggaat aaagaacacc cgcataacca
     2461 tgacaaaagg tagggccggc tatatgccat tgatttgttg gcgatgaaag gtgactagaa
     2521 agaatgtcta tgatatgtcc ggttgtatca acgtcatcca gtaaagttga agctcttaac
     2581 atttcgaccg caattcctgg agtaccgtag caccatccgg ctctagtagg tagaggtgat
     2641 aaaacatcat cttgtatctg gcaattggtc ggtattcgtg caggccaata gtcaaagtca
     2701 tctgcatgct gcgtccaatg aaatgtccat tccataatgc gtttaatgga gtccataact
     2761 cgtgtgtccg tgtaaccata gttaaagacg cttactagtg ttcccaaaat tcctgcagcg
     2821 ccatgtgcga cgcctacatt taaatcgccg tcgggatatt cgttttcatc ctgcttcgtt
     2881 ggttgtaagt tccctggcac ccaccatccg ggcatgcctt gcgagtttga agtaagtacc
     2941 aaatcgcata aatattttac agacaaatta atagtttctc tagcatttgt actattctca
     3001 tccaataaaa tgcggagatt gccacaaatt ccattcatga tgtcataagc aagccatggg
     3061 acaccattcc ccaaagatga acgatatctg ttaattaaat acaactggca cctacaaatc
     3121 caagcggtta gttgctcacg tagttttgaa taatccatag gagatctcga tgcgatctgt
     3181 gctgctgcta gtaggcctga ggggcctccc ataaccccgc cattgataca ccagttaata
     3241 gtggaggttg caagtaaaag atgattgtgt gcaacagcgc ggaatgattc atacttattc
     3301 gctaatatgg aatagaatat agaggtgcca cataaaccat gactgatggt gcagggcgcc
     3361 catactgatg tgtcaaaaag cggctcgtga ttgccgggtt gatccacaat agatttcaac
     3421 tgttttggat caattaatct atgacatagt tcgtcaatta tataaaaaaa ttgtttctca
     3481 atttccggcg gaagaaattt tgattgatct tgtttagaca taattattaa aattctccat
     3541 atttaatcga ttgattgatg cttgtcagga cagattgcgc aattcttagc agcctatcct
     3601 ctatttccgg gtttggacca taccttcggt tcaagcacat atgtagatga ctgcctataa
     3661 cacgggtcgg agaggaggtt gcggtataat tattgcagct ttttttcatc atatatccca
     3721 aatctctata tgctttatac aaatcatcca atttcgatac ctgttttgat tcatgaagga
     3781 ttacggattt tatggattca atccatattt tccgattttt ctgatattcc ttatcgtgag
     3841 aagtcgaaag atttaaataa tctgcccaac gttttccctc ttgcaaatca aatgatttcg
     3901 atttggcata tccattccca aatccggtca gcatgacgca cagcgcagcc aatgaatcaa
     3961 gatcatattc catccccttc ttgtcaatct gctgtagagc attcatagaa tccgtagtaa
     4021 agcactgatg tgttaactcc atcatttgaa tgccgccata tctattgact tcgggtatgt
     4081 attcgttaaa gtcatatgtg cgcgcgtcgc catctacaat tgattttaca agtattgaag
     4141 tgagtctatt gaaatccgta tcatttccat taatccttat tcttaggtga gtcccttggc
     4201 ggtctgcata cctaacaaag aaggaatgct tgacggtaga actattgaaa caatctaaaa
     4261 tatcggtcag gttatttttt agataattaa ccatattttc cggcggcata tagatacggc
     4321 atgataacca gttttcattt cctggcaaaa aaatatggtt attccgtgaa ataatcttcc
     4381 tgtatggaat catactcgta gaggaattag agaatttatg atctatttta tggaaattga
     4441 atacgatttc gctgcaaata gattgcccat cttttctcat ccatccccat actgcatccg
     4501 gattattgcc gccggctgga atctcttgaa ctaggagctg cttatcttta cgcgactcat
     4561 tgattaaaag agtttgatgt aatggattgt ccaagtctaa aagtaatcgc atatcctgac
     4621 ttaccgctag acaataacgt ggaacattcc acttttccct ccagtgtttg catgaagcta
     4681 attcactttc gcgaagttca tcaaggcgcc aacttcttga agataaaata atatggccat
     4741 atcgtacgcg aggtctataa gggaaactat ccaggctgtt ccatgaccag ggattccata
     4801 aacgggctcc ctcattcatt atctctatta atagtcttac ttcattagga gcttgtgcgg
     4861 gcgggtaaac ggtattatgg gctcgtatac ggattttttg tccagtatat aaatctacgg
     4921 cgtacagccc ttctttgttt gcgcgtattc cgatttggga aagggaaata cagtgttcgt
     4981 tgttttcttc tggaatattt actgatataa tcctttcccc ggctatcgga gtatctatga
     5041 gatttgccgc cgcgtcggag cgtgttggat agtttataac tgcactatac tcatctggct
     5101 caaatatagg atttaggaat tgcttctcaa catatttagg taataaagac ataaatcggc
     5161 cagtagtgct accggatgca tgtgatccgg ggtttgggcc aataaccaat aaatagtctc
     5221 cttccgataa ggcggacatg tcctttgacg caatggtgca atacagttcg gcgctttctt
     5281 gcgaatcttc cttatcgaat ttctcgtatt gaagtttatt tatgtcttca tccgtcagta
     5341 taacttcggt tttgttcttt gttatggcat catagaatag tgatgctagg taatgttcat
     5401 gctcctcata gatattatta tttgcgctaa agctagtcgt atttgaatat tggggatatt
     5461 tatagtcatt tggcacacca attccttttg cgggatctgt aagatcgaga attggaaccg
     5521 tttcatcaaa cccatattgt tcaacaaatt cattataata atattgcagt gaggacatgc
     5581 ctttacgatt tttcgagagt atttgcgata tatgaattgc caattcagca tctttttgca
     5641 cgcttttcgg aagacctatg gatattccgt ttccgacctg aaaatgaaca taagagtcgg
     5701 atttctgtat ctttcccatg gcttttatgg tgtcttgata cgattgcata cttggataag
     5761 tgtatcctga gatggaatgg agcttattat ttatttccac taattgctcc actatgtctt
     5821 tatcttcttc ctgaattgcg atgtgagata gtttctcaag cagttctgaa atacgttcct
     5881 caccattatg ggctggtctc aaatttgagt aaaatatatc cgaattgaca agacgcttaa
     5941 tcaagctcag agaggtgtct tcatccacgt tgaattgtct tgatagtcga tcaagaatgg
     6001 ttttgacact gatgtcctta tcatttaata ggtcgtcgat aatgggcgtg catctgatgt
     6061 ccacacgctt attgcacata ctctctttgt taaccgtata tagtatgtaa tgattatgtt
     6121 gcttccttat taggtcattg cgatgcagca ttagttgcct gagaatagac gagtgctgtt
     6181 ccagttttct aattaatgga tttagccatt tgtaatcagc gtctgcatga atgatctttt
     6241 cctcttgtgt tatggttagt atgtcttttc gattaaatgt tcctatacca acttcggcga
     6301 ataaaccgaa gggagttggg cgactcaaag ctcgatttac gtatttactc gttgctaaca
     6361 ctattttttt cagctttcgt gctgatggta tgttctggga accagtaata gcgtcatgcg
     6421 cggattgata taaagaaggt gccgcatgaa tgattgcaag ggatatatac tcatttgagt
     6481 atatatccct taaatatgct agaagttcag ttttttgaga ttctaaagga ttgatttgtt
     6541 gcgttattga gaggtatggc agcgctgccg tgcgaattgt tatgttggga attgcgtcca
     6601 tggctttttt ctcttgtctc attgcaacac ctcttttgaa taaaaacagg tgggagatgg
     6661 aaacagggtt ttatcatctc ccacccgaac cttatctatt gcattagcag cagaaggaac
     6721 atccgctgcc tccgttcggg ctagtgcaac ccggtgtaca aagacttatg ctggtcaaac
     6781 gaatctggtc aatctgttct acaggcaaat cttcaacgtc gatgtcaaga tcgatatcca
     6841 taacatctac agttggcttt tcaagaattg cggtattcat gattcacctc ctttcttttc
     6901 ctgactatgc aattgtttgg caagaggaca taaaaatagt cctttaaaat gtttaactaa
     6961 ttgcatgctc ttggttagtt ggagttttcc ctccaccact atgctcgttc ttttgtgttg
     7021 gatattcaat cattcatcag tcatttgtca tcttgcgatg acagcttgaa ttgttctggc
     7081 tgtttccatt gggcttgtct tttgacgatg catgaccgga gtgtgtattc cgggcttttt
     7141 ctgtgtggga ggctgaatca gcgacctcat cgggctggga gtcatgtctt ctgttttgtg
     7201 gggttatcgt gtcatgatga tgaacatgtc ccgagatttt aaattcacga tatattgaaa
     7261 tgtgcgattt acgtgttttg ataggcgacg tcgaaggatt tggattacgg gccatgctga
     7321 agcgagagat tgaccgaatt gtagtacaag tgctgctttt ggtgcatgtt gtaatgatgc
     7381 tgaaatatgt gagtatgtcc cgtaattaaa ttagggaata ggagctagtt gttttggttt
     7441 ctgccagcgt atatatatat ggctttgtct ctctgaatag ctttcccgta taacgccttt
     7501 caagaaagct gtgcacagac cactgttctt atcgggcact ctttcagaca gtgtgtaagc
     7561 atcgtaatct catggtccgc ggtgttatgc aattattcga catggtcgat gacgttccat
     7621 aatttcgcgt tgcatataat ttggatgatt ctcagtccgt gatcatgcga tatgctgttt
     7681 tgttgcaagg ttatggtaga gtggtatatt ttcgaaaagc tgtttatggg ttcctgatcc
     7741 gataacccgt ccgtggttaa ttacatatat gagatcggaa tcaattattg tggcgagtcg
     7801 atgcgcaacg ataataaaag tgcggccttc tacctgagcc aatagccgag tgataaggcg
     7861 ttcgttatcg gcgtccaggt ttgcggtggc ttcgtcgagc aggatgattt ttgccgtgga
     7921 aagaagggcg cgggctatgg cgagtctttg gcgttctccg cctgatagca tgattccgtt
     7981 ttcccctatc tgcatatcga gacctttgtc ggatcgatct agcagatggg agagattcac
     8041 ggatttcaat gcccgtcggc attcatcatc gctacaatcg tttgatccga gaagtaggtt
     8101 ctctcgtatg ctgccggaca gtgccggtga atcttgttcc acgtatgcga tgtggctgcg
     8161 taaatcgtct cgatcacagg ttgttatgtc cttgccgagt acattgatgt ttccgctgga
     8221 aggatcatag aaacgttcga taagttgcag gatcgtgctt ttccctgcgc ctgagggccc
     8281 gacgagtgcc gtgacgcttc cctgggatat ggagagattc aggtcgtgca gaattggttt
     8341 ggattcatat gagaagtaga cgtgttggaa ttccactgct ggcggacagg ggctgctgtg
     8401 tgccagcggc atatgttcat tgattgttgt gacgacggtg tcagggtcct tttcttcggg
     8461 aatatccaat atttcccgta tacggttcat tgcggccatt gaattgccga tttgtgagcc
     8521 tgcgtaaatg atctggctga gcggtgagat gctgatgaac agcaacatga tgaactgagt
     8581 aagtttctct acggatagca accctgtggt tacgcgccat aatcccagac cgaacacgat
     8641 gatagctgcg agctgcaggg ctatcgtggc cagtggattg acgatcgact ggattctggc
     8701 gatcttgagt ccggacaggc ggacatggtt gatcaaggcg gcaatgacct tattctcgtt
     8761 ctcgaagccg tttgaagcac gtatggtgcg gatgccggcg agatcacgat tgagcgtgga
     8821 ggtaaggtcg ccgagcgtgt attggctgtc atagcttgct cgttcgatga atttagcgga
     8881 cagcagcatg agcgtgaata cggtaaggag cagggtgatc gctgtgccga ataggattgg
     8941 gtcaagcatt gccataaacg cagcggaacc gatgacggtg atgaagcctg atgcaagggc
     9001 tgatgtgcac tgcatgaatg cattacgcag ttgtgaggtg tcgttgctga cacggctgag
     9061 caggtcgccg gagtcgcgtt gatcgtattc gcgtatgggc agacgtagca ggtgtttgct
     9121 tagtgcgaga cgagcatccc ttacgatatc ctcccccgtg ctctgaagtt ggtagttctg
     9181 tagggctgat attgctcctg aggcggtgac gagtagcagc attccggcaa tgacgggcca
     9241 ctggggaacc tggaatacac cattctggaa gaagttggtc atgtacttag gcaggagcag
     9301 cgtcatagcg gctcctatgg ctccaaggca taggatgagt gccagccgtc ctcggtattt
     9361 tcggagggga gaaatcagat tgtacatgga ggcaggtttc atgtgcatgg tgtcgtcctg
     9421 gtcgttgacg gtcattgcgt atctttccgt tcggaactgg ttctggtgat ggtgtaccgt
     9481 ctgacggcat caggttcgcc gatgggtgtg ccgttggctt cgacccaggc gtgtgcgcgg
     9541 aagggacgat cggtgaaccc ggtgcaccat gtgacggatc ggcgagatat gcggcatgcc
     9601 gccgctgtgg agagcgaccg aagcagacaa ccctgctggc ttcggcatct gcggcttacc
     9661 gcgcatacgg cattgcggta acgttccgcc atgctggtgt cggccggcgg atatcgttcg
     9721 gaccacgttt caagccggcg gcagaactct ccgatttgct gtcgttccat ccgtctgccg
     9781 atgatgatgg caatcagcgc tatcaggcgg tcgtgaaagt tggctcgtgt gatcgcttcc
     9841 ggctgtagtg ggatgctcat agacgcacgt gcttccccat atcggcgagg aaacgatccg
     9901 cgtcccgggc gatgatttgt ctgtcggcct gatattcttc ggcgatttta ttcgtgcaat
     9961 cctcgacggt tttgccgcac atcagaccgt caaggataat ccggcctatt tcgttgacct
    10021 gcaggtattc accggtgtcg ttgacgaaga cgatcgcccc gccctccttg ggatacaggg
    10081 atatctgatt cctcagactg atgcttgtct gtgtgtcatc ggcttgcata tctcagccac
    10141 ctttccactg ctgctactcg ttgcatttca aacaggaatg tgatgtcagg catcggcatg
    10201 gaagctcgac gccgtatggc tggcatatcg atcagtccct cctcgtccag cactccgccg
    10261 gcgattgagt cgagcagtgc gtccttcgag cgttgccatg ccagatacag tgaatatgag
    10321 tgatcgcctt tgacgggacg ccggaatatc gtttcgggga ttatgccctt gagcgcccgg
    10381 tataacacgg ctttgtgtag atttccctcg gtgcgtgcac tgattggggc gcatagcgca
    10441 tagtccgcga ttccgtggtc cagatagggg gagcggaacg ttatgtcgtt ggaggcgaac
    10501 gtccgattaa cctgattgag cattcgtgcc tgcattgaca gagagtagag cgcctgatga
    10561 cggcttcggt cggggttcaa tggccgaatg tcggcgtgtt tcaattgtga ttcaacggcg
    10621 ccatatagga tattcctggc tttcgcggtc aggaattcgg gaatgcgtat ggcatcatgc
    10681 catccacaag gcgaagagcg atggtcatga ccttgttccg cgtccaggaa cgatgaccgt
    10741 aattcctcat gcagatcggt gccatcggtg agatcgagaa ttgcctgata gggtgggacc
    10801 cggtaatcgg cgctgtattg tcttcggatg tcctgtagcc gtagcgggtg ttcccgcagg
    10861 cagctccatg atgaggatgg catggatgcg aacagctcgt ctcctccgaa acccgtgaca
    10921 tggatacggc ttgcgtctgc ttccatttcg gagattcggc tgagatagcc ttcgatatcg
    10981 ctccagtaga ccggttcttc aggtatctct ctgttgggat atccggctgc gggttcgaat
    11041 gatctgtttc catccacgac ccggccgatt ttgatgagtg gcatccgaac gtcctcggag
    11101 attcgctcgg cccatcggga atcctgattc attggatcgt cgggtgtttc atgatacagg
    11161 ggcatacgaa ccccctcgct ggcgaagacg tatgtgatgg cggcggaatc cactcctccg
    11221 gacacatcgg cggatagtgg tgcctcattg cgccactcat ccgcgatcgt caggaaacgg
    11281 cttcttagtg atgccaagat ctcgttgctc ggaacatgtt ttgcgggtga aggttccgct
    11341 ctcgtatatc gcggcctatt ggatttgtcg aggtgcagta tggttgcggc gggtatggaa
    11401 tgtatgttcc tccatgggga tttgtcccct cgaaggctgt cagggagcga aggcagcaaa
    11461 tccatgacaa tgcgttccag gtcaagatcg gcgttcgtga tgcttgcaag tcgggaggcg
    11521 ctgtccgaca ggagcacttc atcttcggag acggtccaga acacgcgatc gccactcagc
    11581 agaggaactt ggacgcatgt tccctcgtca ttgatgctga tggaggcggg aagcttcgaa
    11641 cagttcgtcg gcttcccgcc gcggacaatc acggtacggt ttgggttctt atgcgtaaac
    11701 ggcatcacgt ttccctatcc tgatacagct agggatcatc aatatatgca gggtttcggt
    11761 cagttcgatc cccaagggaa cggggccttg gcgccgccaa catcgacata gttgccgaac
    11821 catacgccat tggttgcttc cttgaatgat gcgatgacct caacggccgg gggtacataa
    11881 tccttcatct tcgttctcct catgctctgt atatgggacc ggattgcatg ccggtgcatg
    11941 ccattccagt taacctgatt tggatggtac atccaagaat gtgtttggtg tttgtcatct
    12001 tcggatgaca aacaccaaac acatggacct tagggaagcg ggtgatccgc tggcgttttt
    12061 cagtcttcct tccaaagctg gccgcgggag ccctctttta ccacggtgcc tttatccagt
    12121 accacaacgt catcggtaat cggcctcagc ctgctgtccg gttcggatgc gatgagcacc
    12181 gcaacgccac gattcgcctg cttccgtatc tgctcgcaga tccaattcgt gcccgatcga
    12241 tcgagtgtct ggagcggttc gtccatgatc agggccttgg ggttgggaag cagagctatg
    12301 gcgaatcgca ttttgaggac accgatcgga gcgagagcgt ggagcttgac ggtgagaaga
    12361 ttctgcagtt cggtcatgtg aatgatcccg tcaagaagcg gatcaggcgt tccggcccag
    12421 agcgccttcc aacgaagata ggttccggcc gagtaatacg gggaccgtga aatggcttcg
    12481 ggcattgcac tcacaacgtt ttttggtata cgggatgtgc catagggttt gccacaggtg
    12541 gatatgcatc cggaatccgg gatatccagt cccaacagca tccggagaac agttgttttg
    12601 ccagcgtcat gcgctcccat cagaacggtg actcgacctg cataggcggc aaatgagatc
    12661 ccatgcaatt cgcgaccggc atgattgaat gagacgttct caaatgcgat gatgggtgaa
    12721 gccgaatcgg gcagctggca catcgttttc ctttcttcga ttgacccgag ccgcaataat
    12781 cgaagtcccc cccccctaac ggtttttgga tactgcccta tcttagggga tggcagaagt
    12841 gacgtgatat atgctaggtt tgttccgttc gcttgagcga tggacataga cagttaacca
    12901 gttcgctcta ttctccaata aaaggattgt ggtgtttgtc atctgaagat gacaaacacc
    12961 acaatccttg agatgaatat cgtgattttt atgctggttt gccgcctgtt atttggtcca
    13021 gccccgattg ataccaggct atggcgattt ggactcggtc ccgcatgtgc attctggcca
    13081 atatgcggct taccgtgcgt cgtaccgatg ccgtttcgat gaacaagtgt tcggcgattt
    13141 cctgattgga caagcctgcc gccacgagtt ccgcgacttc atattcccgc ttggaaagtc
    13201 cgtcgaatag gcttcgcagc agcttgatgc gggtgttgtc cgatatgggc cgaaccccgc
    13261 gattgagcac ttcaccggtg attctcggtg tcaataccgc atctccgtta tgcacggcgt
    13321 gtacggcgtc acgtagctgt ttgggggtcg catccttgag caggaatccg gatgcccctc
    13381 gcgccaatcc gtcgaaggcg taatcgtcct catcgtatgt ggtcaggatc agtatctgga
    13441 tttgggggaa ttgctccttg atgatgcccg tcgcctctat gccgtccatg acgggcatgc
    13501 gcacgtccat cagaatcacg tcaggcagtt gctgcggtga ttgccgtagg aattcgattg
    13561 cttgggcgcc gtccgcggcc tgtgagctga cgatgatgtt cggatcgttg ttcagcatca
    13621 tcatgaagcc ggtgcgcgcc cctcgcatgt catcgaccag catgaccttg atgatgtcgt
    13681 ctcttgcatc cttcatggtt cttccgtttc tttcagggga ttagtgcctt gaccgcccag
    13741 ccattgccgt atggcccata ggacagggtg ccgcccattt tcgcaaggcg ttgggagagt
    13801 cgttgcagtc cggttccacc tgtcggcttc ccgctttgac cggatgcctc gccggtggtg
    13861 ccgtgtccgg agacgtgtcc atcgttgcgg atcgtgattg ctgttccgcc atcacggtaa
    13921 tgattccagg agacggcaat gcgggtcagt cccgcgccgt gccgaagggc attggtcagt
    13981 gcctcgcgag tgacggcgaa gcataaatcc gaacggcggg gatcctcgac gcgtcttccc
    14041 gtttcggtga acacgacgat gattccggtt gagcgtatgt gttccagtac gggtctgata
    14101 tcgtcccaat cccgtaaacg aaggatgtca tcctgattca ctggttcaag accgacctgt
    14161 tccaaagatg gctgcgattc ctcttcattg aagaccttta agatgcggcg cgtatcaccc
    14221 agactgtcct tcgcaatcga tgtgatctcc gctaaggcat cggccagttg cgagtcggaa
    14281 tagccgccgt tccttatgca gtcctcacct ccctgcgata acgcgatgat cgaggtcaat
    14341 ccatgaccga cgctgtcatg cagttcgttg gccatgcgaa ggcgccgttc cgtacgattc
    14401 ttctcctccg ccagtattgc ggcctttcgc cgtgcctcgg acagtagcct attcgccgtt
    14461 cgacggtccc gcgctatgga caacagtgag gatgcgatgc cggccaaagc gacggaatac
    14521 agtaacgcca aatactgagg ctgcagagag gcgggatgca tgtattgcat tgcgatcatg
    14581 cagatcatgg ccagatcgca catggcctga gcatacaggg gaagccgaat gcacagataa
    14641 agcaccagga taagagcgac ctgcgtgtat gagtgcaggc caacgccgaa caggacgccc
    14701 agggagagct caatgaattc caaggccagc aacgccacgg ggcttctgaa ccttaacgtc
    14761 acgtttatgg ctcctaaaac cagcagtatg aggaagtacc atatccccgc tccctcgttg
    14821 aggaaccgga taaacgaata tcctgtgccg attgccatcc gctcttccac ataatcgcgg
    14881 atcagcacgc ccatcgtgcc gacgatgcag atcagagttg tcgtgaaacg aagcaggcgt
    14941 tcccctttga gctgacgaag ccatagaatc aatcgatccc gcggggtgac ggccagcgtt
    15001 tgtccctcat ctgatgactt accccggcgt gagcccataa tgaggcggtt cctcgcaacc
    15061 tgcaccttac gccttcttcg ttgtccgaga atacagctct cccattatct acgattcgag
    15121 gctcgcatgt ccatgacctg gctcctgttt gacatctacg gatgacagta gcttatcgcg
    15181 gacttcccgc tccgcttgcg gagagaatgc tccaggcggg gctgttcgac atactctccg
    15241 caatcggcgc gggaacgcgg ccccgggcca tgcgctacgc gcatgaccat gttgtctggc
    15301 cgcttgcatg ctcgcggcgg tgggccgcgc ggaatctgac gagggggttg cggccaccac
    15361 cagcatgcca tgcgctccgt ctgcgttccc tgcgccgtgt cccgcgccgc tcccgtgcct
    15421 gcgctgcgac ggcgaaccag catgccgtct tcgctacggc ccggatcgtc gcggtccacg
    15481 cctccggtct ctccgcctac gcgcatggca ggcgggtggt gtccgaaatg gaaaccacac
    15541 ggaaaggacc gatggacatg aacgacatgg tggacacccg cacgacggga accgggctgg
    15601 cgaagcgcgt acgcgacggg ttccttcagg accggcgtga acttggaccg gcgcaagcgg
    15661 ccgacaagtg gttcgcgccc ctgatggaca ggtggaacgg cctgctgtcg cgcgacgagg
    15721 gcggcttctc ccatgaggag cgcgtcacgc tggcggtgct gatgaccgag tacctgagca
    15781 tgcgggacgc gctgatactc gcatcgctgc acgaaatggg cggcggcgaa ctgcacatgc
    15841 tgtacgccaa gccgcattcg atggaatcgg cggccgtggt catgcgcgaa ctgtcacggg
    15901 cgttcaagga cgccgactac cagccggaca cgcgacgcgg ggaacgcgcg acggcgttgc
    15961 tggaatcggt gacggccgac gccccggacg gatacgaggc acagccgatg gcgtcgtgcg
    16021 cgtacctgct gtggatggcc gaccgttcga ccgccgccgc ggtgcgcgcg ctcaaggcct
    16081 tggccttgga cgacgactgt tcgctggcgt ccctcgtgct cgcggccagc gaacacggca
    16141 tccgccccgc atggacggaa cgccgccgcc actgagcgtc ggccgcggat tcaatccggt
    16201 cggggcttcc gacgccggaa gccccgacca atcccaatca tccgattttt tcaaggagac
    16261 aaacatggaa accgcaatca tcgaacgtcc cgtaatggcc gacgaaggca tggacgaatc
    16321 gaacatcgtc atgctggatg tggggcttat cgacccgaac cccgcgaacc cgcgccgtga
    16381 cgtgggcgac gtgtcggaac tcgcggattc gatacgcgcg cagggcatcc ggcagaactt
    16441 gctcgtcact cccacgttgc agggacgcta cctgctcgtc atcgggcatc gtcgcctcgc
    16501 cgccgccaaa ctcgccggat tgagccgggt gcccgccgtg gtggccgatt tgtcggaacg
    16561 ggagcaacgc gaactcatgc tcgtggagaa cagccagcgc gccgacctga ccgtcatcga
    16621 agaggccgac ggctatcagg ggcttctcga tttgggcgtg ggcgtggatg aggcggcgca
    16681 acgcaccggc cgttccgtgt cattggtgcg ccgacgcctg aagatagccg ccatcggcga
    16741 gaacgctcga agcaaggccg gaaccgccca gctgagcatc gacgactggg agaccatagc
    16801 cgacttcgac cggtatccag accttcagga acggctcgcc gaggcggcgg gcggcaagaa
    16861 ctggaacatg gccgtcaagc acgcccggca ggagcggaca tggcgcgaat ggctcgacac
    16921 ggcgcgagcc gaattggaac gcatgggcat cgacgcggcc gacgaacagc cgaacacgga
    16981 caactggtat gactcgccga agggattgcg gcgcaccacg atgctgacca cgggcgacat
    17041 cgccaaggcc atcgacgcat ggcgcgactc ccatgacggt gccacgcccg tcgtgggggt
    17101 gcgggccgaa ggcgcgtcat gggcgcgcgg catcgtcctg tacgagaccg tggacgagga
    17161 ggcggagacc gcggcccgcg aggcgcggga ggcgcgttgg cgagaggaac gggaacgcga
    17221 ggaacgcgag acggcaccgg ccaaggagtt cgcgcgggca agccgtgatt tgcgcatcgc
    17281 gttcgtgacg catctcatgg aactgaaatc ccagccgaaa ggcatcggca gggccgtcgc
    17341 cctgctgtcc gcgagattcg cgctcgatgc gctcaccgag ggattcgacc aatgggacgg
    17401 tcacgccgag gacgtctggg agcaaatcac cggcatcgac acgacgggcg acgacgccga
    17461 tgccgaggaa ccggagggcg agaccgaaga cccgttacgc gcgtccgtca ccgcgatgat
    17521 tgccggcgac ccgcaacggg ccgcgttcgg actgctctac gcgttggccg aggaacgcgt
    17581 cagctgggaa acgtggcgcg gcgcggcgac catcgcggaa cacgccgcac cgctgtacga
    17641 ggctttggaa acgctcggtt accgcacctc ggacacggag accgaagccc tcaacggctc
    17701 cctcgcgcca atcgatgaca acgacaatgg cggggatgcc ggcataaggc aggacggcga
    17761 accggacgac gacgggacgt cgcagaccga cgacgcatcc ggcaagccgg aagacgccga
    17821 ataggcgacg aactgggcgg aaccggaata agggttccgc ccagtccggg cgcggacggc
    17881 gaaacgtgac ggcgcatgcg cgcccgcacc tgccggagcc aagcggcggc aggtgacgct
    17941 cagccgtggc gggcggagcg tcgtcggagc cgcgcgtcgc accaatccat gagcatgctc
    18001 gcaagcacgg ccgtgaggaa cgcggcgacg atcaacgcga acgagccatc caatgccgga
    18061 gcgtccgaac cggcgaggaa atgcatgagc aggaacgcca gcatgagcaa tcccgacagc
    18121 atggcgaacg ccgtgaacac ggagttcgca aggaacacca cgagccgcaa cgggtgcgcg
    18181 agcagggcaa ggcacgaggc cacgccccgc atcagcatgc gtatcacgcc cgtcgccagc
    18241 gacaggccaa gcatcaccag cagcatcggc atcgccgtca cctcccgtat gtcgccaatg
    18301 tcatccagcg tagccgccag gacgcgggaa accgaatcgc aacccctccg ggtccaatcc
    18361 aatcgaaccg gacgtgccag catccacggc atcagccgca ttctccgttg cggcgttgtc
    18421 ctccgtcagg gcagtctccg gcgcatcggc ggcggatgcc ggtcggccgc cggattcgac
    18481 ggccgaatcc tcgccatcat ggatttcgcc gtggctatcg gcgggattgg cctgcccgta
    18541 gtcgggagtg acggcatgga acgccatgcc cgtctccctc ggctccattc tgagcgtgcg
    18601 cacaagctgg gcgcgcggca tgtgatggtc gtcgcagaac gactgggcgg cgtcgcggaa
    18661 tcgttccgcg gcccagcgca tgtcgtccag caggatgccc aaacgcgaca gttcgccgcg
    18721 tttgcgccga agcgcctcca actcggcatc caatgcgttg tctgcgatgg cgcgcatcgc
    18781 ccggttgcgt tccctcggct tcgccatgac ggtctcctca cggtgattgt tcttcgttgc
    18841 cccgcatcgt agaatgacgc cggccatgat gccggcggac acgaaacgga accggcgccg
    18901 gcatgcgaaa cgtgacatgg agtccgccgc gcatggcgtg gcgcgaaggt gaaactgacc
    18961 ggtgcgcaac catcccctcc ccggaggggc ggttggtgtg cagcaagcat cgcccgtgta
    19021 cgtacaccgg cgcggccccg cgaggctcgg ggccgattac gggacacccg tggaacccga
    19081 tacgaggagg caccgatggg ctggaaaggc aaccgttcca gaacgatccg caaggcggtc
    19141 acgttcagcg aggaggaatg gcggtgggtg gcggactcgc tcaaagtgga gaaccgtcag
    19201 cgcatccagg ccgggctcag gccagtggga tggatgacgt tcgcccgcaa ccggatcaga
    19261 tgcgcccacc gcgtcaacat caccgtgccc gcgaacctgc atgacgtgag cgcccaacta
    19321 gcgaggatcg gcaacaacgt caaccagatc gcccgtcacg cgaacaccac gcgggagacg
    19381 gacctggcca tgctctcgcg cgtgttcgac gagctgcgcc aggcggaacg gctggtcgcg
    19441 ggcctgagca tccgggtgga gaccgatgtt gaccccaagg gggtgcccga atggctgtag
    19501 tcaagattgg caagatcaaa agcacgctcg cccgcagcat cgcctacgtg acgaacccgg
    19561 ccaaaaccga cggctaccgg tgggcctcga ccaccgtcgg cgatgacatc acggacgccg
    19621 agtccatcgc ccgcggcttc gaacgtgcgt tggacgccac gaaaggtggc tcacgccggc
    19681 agggggccgt gttggcgctg cacgtgatcc aatcgttcga tcccaccgat caagtcacgc
    19741 cccgattggc gcatctgatc ggggaacggt tcgtccggga gatcaccgga ggcacgcacg
    19801 actacgtgat cgccacccac accgacaggt cccacatgca caaccacatc ctcatctgcc
    19861 cggcagaccg gatcacgggc aaggccctgc gtctgcggaa agggaccttg ggcgaatggc
    19921 ggaagatcag cgaccggctg tgccgcgaat acgggctgca caccctcatg ccggaacagt
    19981 ccgggcgcgt ggccccgtcg atcggggaac tccacctgag cgccagaggc ggcaacctca
    20041 aggaccggct gcgcaccagc atcgacacgg cctgcatgaa cgcccatgac ttcgcgggat
    20101 tccgccgcga actcgcgacg ctcggcgtc
//
