LOCUS       c00021_JAHODT0..       16666 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAHODT010000029.1 Bifidobacterium breve strain MSK.22.106
            NODE_29_length_18099_cov_374.052, whole genome shotgun sequence.
ACCESSION   JAHODT010000029
VERSION     JAHODT010000029
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 03:30:22
            Original ID  :: JAHODT010000029.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16666
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16666
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2704:6666]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2705..6666
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..16666
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16666
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03882))"
                     /tool="antismash"
     CDS             3..251
                     /locus_tag="ctg21_1"
                     /transl_table=11
                     /translation="ALSNGIVGFVVVAAGMVGNATAADMTAANIRTFKTCAYYLPLAGI
                     VASLVVFLLTVKIDENMHDRIVEQLEARLASEETDKQ"
     CDS             669..1325
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 140.9; E-value:
                     8.7e-43)"
                     /gene_kind="transport"
                     /locus_tag="ctg21_2"
                     /transl_table=11
                     /translation="MPVISATNLSIGYKNSPIVSDINLRLNTGRIVCLLGANGAGKTTL
                     MKTLLGRIRPVSGEVTYTGTNINEMSAAIDHPSFFPYLSGRENVEVVSAFWGLDVDPET
                     ALNNVGINHAAHGRKAKDYSTGMKERLELCLALVPHPRFLFLDEPQNGLDPDGIASLSE
                     TLRAYRDRGNCVVISTHLLHEIQGVPDECIVIRHGRAAQFTDLTGVNLADLYQGR"
     CDS             1328..2056
                     /locus_tag="ctg21_3"
                     /transl_table=11
                     /translation="VSAVSPVRALVAYYWNVWYFLAAVFGAVASLLLGSWISGAANGTP
                     IAGGYSFFFTGTQPVICLALLFVCDARVAKAHYGGLPRHVYSAWKPCSLRTIFRALILA
                     AVNLLSVLCFDVIMVLMGTGMHPNLAVVLCFVVLQSLLTALIYSIVEIAVNPEVAGIVS
                     AILCYVWVLLPGDLSDYATPYVANALRVVGLNLNGTVMSPAETASRSSVGPVVVVVPIV
                     VLLVVYVLLSWFRREGVDRK"
     CDS             2053..2679
                     /locus_tag="ctg21_4"
                     /transl_table=11
                     /translation="MKSLLRIERVALIRWSMLAFVAVLLLPLFFLRYGSMGAVAQSAMV
                     MALPITTAGLVFSHARVPRSYRSFSIHDRLLLRFTLKSLLLGVAVSICLTLLYGFAVGF
                     IVNKRPLSLHVALMFAFTAVVLSLACFVLRLWASPVVAWSIVGFFIVAGLPVSSGMFEG
                     SPILHAVIPTTWMLSGARFAGYVIPVGVVVAMASAWLLLKAVKRV"
     CDS             2705..5464
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     201.6; E-value: 2.7e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_5"
                     /sec_met_domain="Lant_dehydr_N (E-value: 9e-29, bitscore:
                     90.1, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.6e-13, bitscore:
                     39.8, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.3e-09,
                     bitscore: 28.9, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRIAALPVDKFPKKGSSALSVFADTVISEPGIRAVLENSAPSFYA
                     AVTKNLAEDSKTERTKVLKVARSALKYLSRLTTRATPFSTFATVGVLENVVSNPDGLEL
                     EVGQRRILERIAVGIDDIEKTFTFNPSAYLLGERLYIPSPSKSQETISVRYSEAVQAVK
                     QVTEGRLIGLEQLSSTLATKFGTSEGLSAFIDGLIDSGILLAAPISYQMRDWKEDLASS
                     DVTSTVQLFSLARFSGTFPSNLIDDTGLAIELMGRLFSFSTQNRNIESFTERYISRYGN
                     FRFPANQVIDNYDGIGLLPPLESEDLQPAGQGKARFDLTNKFLSEVIFTNSDKSSIDLS
                     RYASRILREWPAVEFASSYDVILKVEKVNSQTCEASTNFVFDDIGTIPLAGRAMARFAE
                     LSAEMKNNHREIVTRASGLERTERLPLLYRYNSPRPDFLSGNSSVSGNALSLGFLPHVE
                     QAVSIVGLSDISVFESSGKMYCFDERHQKVANIHLPGLVNQDLLSGIGRSLVQISQMNQ
                     ATPYWSWLGYENHANHLPEIRLGVTILSREKWKLTNRGIGALDDLKRVLADRRVPRYIY
                     AGASDNKILLDTSAFDHLRLLKHVIENSDEDIWIERGVEPEDLGVTKSESDDKARFATE
                     IVISVSSTDWAETATLPVAQIPPVGLNLDLSKRSVLESSTAFTFVVLCNDSNQERVLAT
                     AFDVLDDAGLEAYFVRYSEEGRPSLRIRVRGSFDDTFIRVFCDSVLSLRLATDVEFNLR
                     LPEYSRYGGPECFKYLESFWCLESTQLVKMFTRLSSDTPEQVQKAKSNYMRFLIQQLGF
                     TRHYVSAVAESYEHEFEADRHSIRKAARALRSVFSSDDMPEVFTDEMQEVLARFSSCQL
                     QSNASAQDVKQSIAHMSANRLGLDRKDEAIFWRALLNHLRSADFGGEE"
     CDS             5461..6666
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     104; E-value: 1.3e-31)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_6"
                     /sec_met_domain="LANC_like (E-value: 1.1e-23, bitscore:
                     73.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTRNDIQQEVTLIASNLEDIIPIRYQEANRTKSFNINGGTPAAI
                     LYLSVLDALFPDAGYDVQAHNYATSMILEYKHTPNIGIGLFGGTTLLAWCLQSISRGGS
                     RYQGAIRELESRIVFQARQQLTFLSNVNAPISSEYYDVISGLSGVVLYGMRFRSDGLRL
                     ISRQICSRFCELLATSNFHAFGSLSATSGQDSVAQKTTTDYGYAHGILGVLMSCILSDV
                     NHDNNMEPFAAIRQLVDISNHSRNYILPYSSSDYTETVSNGRYAWCYGNMPFYFLSLML
                     KPVDPIIAESLLNVAIAPLKVNTSQVHDLGVIGLVDNSICHGRAGIVLGLHPYLSHKDS
                     RPIRDQLLEEIDCSVANPIDSGFLEGDLGTLAVRVALEYTDSIAHLPAFFPFVSPTLWE
                     GI"
     CDS             6663..7535
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 139.1; E-value:
                     3.2e-42)"
                     /gene_kind="transport"
                     /locus_tag="ctg21_7"
                     /transl_table=11
                     /translation="MIARALNVTLIYGKSRNPVLHSLNLEIDSGQVLPILGGNGTGKTT
                     LLKALSGLLRPHLGRILIDDSDLYQKRGSALRRLSSSLYSERSFYYRLSARENLRYFLS
                     LRGIYGRTAMSSIDMALDRFDLLGLQDIPFMHLSLGQRKRLGLARAFAAPASLYILDEP
                     TANLDAKSCRLVYQAMTDKSADGASILFSTHNVADLATSTGNVIYLKNGNATRVHLETR
                     DSITARKRFRIVGSLDPESIASIPEVSCVISQSEVEVDIPVGKSLGSVLQSFERIGIEV
                     NEVIDDRSR"
     CDS             7537..8346
                     /locus_tag="ctg21_8"
                     /transl_table=11
                     /translation="MHSFLIGLYLYLRREFLELVTYKLSLMLGVVSAVVGIVQFAFLAV
                     FLQQGNSFPSLQNYGGSVMAFLVSGALFTGFMSSSLSSFSQLISSEQRTGTLEAVLTTP
                     FSIGRVIAYAAVSSFIQLVIGTFLMITFFGIAFSIPFNVNPWQLILVMILGYFTLVGLG
                     LAGGGVLLVTKKGDPVTWLLTTFTTLFSGVLYPVEILPQWLQSISWYVPTTRILSSLRG
                     ALTGYTSMFMLDVVYLIVASIVSMSIGLLVFRWGLNRAIWDGSATSY"
     CDS             complement(8640..12935)
                     /locus_tag="ctg21_9"
                     /transl_table=11
                     /translation="MRFGKKGAGAVASITAAAALLACLVPVALADNGGGGSGEDGGGSG
                     GGPTQTADVHWIYKDSWPATLDGMKTALSDAKVRLSSDLANGQNQFVNMNKTLSDAIDE
                     CQRSYTGEGNADCRLVAVGYVRLADGSFNGSYVSSNAKNRWEAQWKAEAKGDYTYQGQK
                     YSTSTTWKDKLGTRSVDSLAQESIDSNPNASFRVIVLAQNQPPVDYKLNVTTSHKQKTD
                     MQVGSTDPIGDVIHADNGGSAIRETLNGTAIIHYENGPYLPAKSVSKPISFPSNGDTQL
                     DDLASPKDFGMEHWAEGTYWIDIQVPKQGRMQAAVDTADRDPTESWKVSSVPPEPPVKK
                     IEDGVSADRMTNRTTITYGTGRGGYEMRFRDVIEPNGVEYSVDNYRLIDRIDGNRDVSG
                     EFEINWDKASNTVSAARSADKGEMPMDHVYEFSFDVTVSKPSDFQQVKDHAWGKWNHEP
                     EADAGKKQFDTWRPNPDKSWIRLNAKGQWEAVIDPKETNRTGADDMTLLDGDRVASVVN
                     GTIAKNLIQAPETLTLTDDWSAADYLFDADDKSKIKVYEADAGTDRESSVTDIANHGRD
                     VTDQWTITMEGTTVTATAGRAYREGLKGLKTAKQVTLLIPGKAAYANGKGAGQVRDDFG
                     KQASDELSFCTAPDGKALTNKGSQTVNTHTIPTNEPKICGYIPPVVKDVVGESSQGGDQ
                     ASVDGRVVYPGQRLEYRLETQPHLPGNLAYSVSEVAVTDTYDEHLEVDKQTLEVTDLST
                     GRFIPKTEYETQWNDAQHAVRLVFSDGYVKTNWRNGANPRIIVRFEGTVAKDAPTDTKI
                     GNQWALTLNNMITPSNKVWNEPPDFTPVKKDTQADPSISIDGKTALLGDRIYYRVTIDA
                     KQTNQAYKVWRLGMTDDWDDEYLSLDAKRIEVTDTATGKDVTAKFNIAAIDGVAYVYAK
                     TADTKVPATGETIKGDPQPKNLKEYAEKKDHDPLKEPAIDQSMLGTSYEVSLPMTVIKV
                     TDGHIVKNKATQVVNDTRKDTNEVANPLKPVNPSKDVVVKVDGESIDKRSVYLNGLFLY
                     RLDSSVLPAHRAYQKVTDWSITDPLDTEHDQYTGQWAVYAMRDLTEQGRVIARKGVKIA
                     GSGFDASVYGGELFTLTQDDKGVVTVTATQRMLDLVSGNDESEQAWTAFIQCKRVKTGE
                     HIANRFDETLNGTKRPSNQVETHTPDMTPSLKIEKWDEASGWPAGDRDQVKDALAMQGD
                     TRIVFTITNTSTTDPDTKQGAWYRTKDLNLKDQLVAGDGRVTDLEYPADWDSRVLKPGE
                     SVEVKGILKGVTDHHTDRATVTGTPLVECVVSDPDPFDGKDETSAPDDAVTIDGRLVCP
                     DTEVVSNTDDWNGYRTGLAHTGAAIQGVIAAAITLLAVGVGLVAARRFRHGNSAGGRHS
                     ESAQSSDIADTDEDVAETTDEIPYESSVS"
     CDS             complement(13240..13551)
                     /locus_tag="ctg21_10"
                     /transl_table=11
                     /translation="MSQRIHLSENQLHAGLVFPQMKETTPVKKRPIVRTILFPNSSRAL
                     VDKTGKILSVLMGPEQIIGISGFQIRTRLGKNGVQCRSDWGQNVRKCVDLVQIDKIFR"
     CDS             14047..15252
                     /locus_tag="ctg21_11"
                     /transl_table=11
                     /translation="MSTFNPEGIALKQRLAFNPERIALARRLEGVTQKELSTRSGLSQA
                     KLSKLQNGIISFNESDAVKLSGALDYPISYFEESGTVIPLSELTYRKTSRSSMGELNSV
                     STEYSLLMDVIQKLCHVLKMKKNPAAWIDEIAPHEQSLSEEKIERLAIRTRECLGLKPD
                     GAVPNVTRAIERAGIIVSPMRSLNMRGGANLTSEGVTAPSSQWHAMCIGYLGNGALGGD
                     RLRFTKAHELGHLILHRYRKPDSPQLVEREAHIFAGAFLISQLDARLVLKSNLSLRDFL
                     PIKAGWGISIAALISRSHNLGIIDRQRYTSLNIQLSGKGWKKQEPVPVGIENPLLLKQM
                     ITSAYGFKTDQGLKIDSIGLASELGAPFRYLDYWSDGLDDEGMHWGIAANRFEQRPNRM
                     IA"
     CDS             complement(15586..15843)
                     /locus_tag="ctg21_12"
                     /transl_table=11
                     /translation="MNDNHNENEEPFDGTSEDSTLEDQMSAHIAAIAASGVAAEAEALA
                     NRQADMAAKERRETRLAILAAIGIFGAVIVYIITHIAENH"
     CDS             complement(15990..16397)
                     /locus_tag="ctg21_13"
                     /transl_table=11
                     /translation="MDYSMEVSVLGDRISIGEEAHVITLGVNTGFPAGSTAGLAYTLSP
                     LQARVLGAQMRAAADAAEGHPGMPSDEEVNAAAKVFCGGVWNGFDPASMMPTEQFDRFW
                     GDGEGHQLYLEIARHALIAARMSILAGQNES"
ORIGIN
        1 gcgccctgtc caacggcatc gtgggcttcg tggtcgtcgc cgccggaatg gtcggtaacg
       61 ccaccgccgc cgacatgacc gccgcgaaca tccgcacgtt caagacctgc gcctactacc
      121 tgccgctcgc cggcatcgtc gccagcctcg tcgtcttcct cctgaccgtc aagatcgacg
      181 agaacatgca cgaccgcatc gtcgagcaac tcgaagcgcg cctcgcctcc gaggaaaccg
      241 acaagcagta agaaatccaa ctacaaacaa aaagaccttg ggtgggttgt catctataga
      301 tgacaaccca cccaccactc aagtcgttcg aatcgtaact gcgcaattat ttacagtaag
      361 tagttattcg cattgcgggc aactgcttac tgtccattac gttcagattc gaaagattgg
      421 agaagtcatg gccacttttg accttgatac ccatgttgag gaaactgagg gggacgctcg
      481 tcctctgatt acctcgaagt tcatgtgcac ccctggctgc ccgaccggcg gccttgcctg
      541 cttcacttcc caatgtacca atggttgtag cttcaccggt ggaagcaagc attagcaacg
      601 tcgtcgtagc atcgtgcgtt cctagaggca agccttgtct ctaggaacgc ctttttggaa
      661 ggtggatcat gccagttata tcggcgacca atctctcgat tgggtacaag aattccccga
      721 ttgtcagtga catcaacttg cggttgaata cgggtaggat cgtctgtctg ctcggggcga
      781 acggcgcggg taagaccacg ttgatgaaga cgctgctcgg gcggatcagg cccgtgagcg
      841 gggaggtcac atacaccggg acgaacatca acgagatgtc cgcggcgata gaccatccca
      901 gtttctttcc ctacctgtct ggtagggaga acgtcgaggt ggtctccgcg ttctggggtc
      961 tggacgtgga cccggagacg gcgttgaaca atgtgggcat caaccacgcg gcgcatggac
     1021 ggaaggcgaa ggactattcg acgggtatga aggagcgtct ggagctgtgt ctcgcccttg
     1081 tgccgcatcc gaggtttctg ttcctcgatg agccgcagaa cggattggat cccgatggca
     1141 tagcctcctt gtccgaaacg cttcgcgcct atcgggacag ggggaactgc gtcgtcatct
     1201 ccacgcatct gcttcatgag attcagggag tcccggatga atgcatcgtg attcgacatg
     1261 gccgggccgc gcaattcacg gatctgaccg gggtaaacct cgcggacctg tatcagggga
     1321 ggtaaaggtg agtgccgttt ctcctgttcg cgcgttggtc gcctattact ggaacgtatg
     1381 gtattttctc gccgcggtgt tcggagccgt ggcgtccctt ctgctgggtt cgtggatttc
     1441 aggcgcggcg aacggaaccc cgatagctgg aggatacagc ttcttcttca ccggcaccca
     1501 gccggtgatt tgtcttgcgc tgctctttgt gtgcgatgcc agggttgcga aggcgcacta
     1561 tggaggtttg ccccgccacg tgtattccgc atggaagccg tgctcgctca gaaccatatt
     1621 ccgggctttg attctggccg ctgtgaacct gctgagcgta ttatgcttcg acgtcatcat
     1681 ggttctgatg ggtaccggga tgcatccgaa tctggccgtc gtcctgtgct tcgtcgtgct
     1741 gcaaagcctt ttgactgccc tgatttattc gatcgtcgag attgccgtca atcccgaagt
     1801 cgccgggatc gtctcggcca ttctttgcta tgtatgggtt cttctgccgg gcgacttgtc
     1861 cgactatgcg acgccctacg tcgcgaacgc cctacgggtc gtcgggttga atctgaacgg
     1921 caccgtgatg tcgccggcgg aaacggcgag ccgatcgtct gtcggccctg tggtggtggt
     1981 cgtcccgatt gtggtgctcc tggttgtcta tgttttgttg agctggttcc gtcgcgaagg
     2041 agtggacagg aaatgaagtc cctattgcgt attgagcgcg tggcattgat ccgttggtcg
     2101 atgctcgcct ttgtggccgt gctgctgctt ccgctgttct ttttgcgtta cgggagcatg
     2161 ggcgcggtgg cgcagtcggc gatggtgatg gcacttccca taaccacggc cggccttgtt
     2221 ttctcccatg cgagggtgcc ccgctcatat cgttccttca gcatccacga tcggctcctg
     2281 cttcgcttta ccttgaagtc actattgctt ggtgtcgcgg tcagcatctg cctgactctg
     2341 ctgtacggat ttgccgtcgg atttatcgtc aataagagac cgctctcgtt gcatgtcgct
     2401 ttgatgtttg cgttcaccgc tgtcgttctt tcccttgcat gcttcgtcct gcgactctgg
     2461 gccagtcctg ttgtcgcttg gagcattgtc ggcttcttca tcgtcgccgg ccttccggtc
     2521 agctccggca tgttcgaggg ctcgccgatt ctgcatgccg ttataccgac cacatggatg
     2581 ctaagcgggg cgcgatttgc cggttatgtg attccggtcg gtgtagttgt tgccatggca
     2641 agtgcatggc tgctgcttaa ggcggtgaaa cgtgtctaga tatactctgc tcggatctcc
     2701 atacgtgagg attgcagcgc ttcccgtcga caagtttcct aagaaaggca gttccgcgtt
     2761 atcggtgttc gcggacaccg tcatatccga acccggtatt cgtgcagttc tagaaaactc
     2821 tgctccatca ttttacgctg ctgtcacaaa aaatcttgca gaagattcga agactgagcg
     2881 aacaaaggtt ttgaaggtag ctcgaagcgc gctaaaatac ttatcgcgcc ttacaactag
     2941 agcgactcct ttttcgactt ttgcaaccgt tggagtgctt gagaatgttg tatcaaatcc
     3001 cgatggtctt gagttagaag taggacagcg acgtattctc gagcggatag ccgtagggat
     3061 tgatgacatt gaaaagacct tcacatttaa cccatccgct tatcttcttg gtgaacggct
     3121 ttacattcca tcaccatcaa agagccaaga gacgatttct gttcgttaca gcgaagccgt
     3181 acaagctgta aaacaagtaa cagaaggtcg cctaattggt cttgaacaac ttagctcaac
     3241 actcgcaacc aaattcggaa cctctgaggg cctaagtgct tttatcgatg gccttatcga
     3301 ttccggcata ctccttgccg caccaatctc ctatcaaatg agggattgga aggaggatct
     3361 agcatcgtca gatgttacct caaccgtaca gctattttcg ctggcacgat tcagtggcac
     3421 gtttccaagt aatctcatcg acgatacagg attggcaatt gagttgatgg gaagactgtt
     3481 ctcattttca actcaaaata ggaatattga atcctttacg gaacgctata tttctagata
     3541 tggtaacttc cgttttcccg ccaaccaagt tatcgataac tatgatggca ttggtctgct
     3601 tccgcctctt gaatcggaag accttcagcc tgcagggcaa ggtaaagctc gatttgattt
     3661 gaccaacaaa tttctatctg aggttatatt tacaaattca gataagtcaa gtatcgattt
     3721 aagccgttat gcttctcgca tattaagaga atggccggca gtggaatttg cttcatccta
     3781 tgacgtcata ctgaaagtcg aaaaagtaaa ttcccaaaca tgcgaggctt cgaccaactt
     3841 tgtgttcgac gatattggaa caatcccttt agcaggacgt gccatggcta ggtttgctga
     3901 gctctctgcc gagatgaaga acaatcatcg tgaaattgtc acccgagcat ctggccttga
     3961 gcgcaccgag agattaccac tcctatatcg ttataattcc ccgaggccgg attttctaag
     4021 tggaaattct tctgtatccg ggaatgctct atccttggga tttttgcctc atgtcgagca
     4081 agctgtttca atcgttggtt tgtcagacat ctcagttttc gagagttccg gcaagatgta
     4141 ctgcttcgat gaaaggcatc aaaaagttgc aaatatccac cttcctggct tggtaaatca
     4201 agacttgcta tcgggaatag gtagatcatt ggtgcaaatc tctcaaatga atcaagccac
     4261 accatattgg agctggttgg gttatgaaaa tcacgctaat cacttaccgg agatccgcct
     4321 aggagtcaca atactatcac gagagaaatg gaagttgact aataggggaa ttggggcgct
     4381 tgatgatttg aaacgagttt tggctgatcg aagagttcct cgatatatct atgctggtgc
     4441 gtcagacaac aagattctgc ttgatacttc agctttcgac catcttcgac tcctaaagca
     4501 cgtcatcgaa aactctgatg aggatatctg gatagagaga ggcgtcgaac cagaagattt
     4561 aggtgttacg aagtctgagt cagacgataa agctaggttt gctacggaaa ttgtcatttc
     4621 ggtttcttcg actgattggg cggagacggc gactctgcct gtcgctcaga ttccgcccgt
     4681 cggtctcaat ctagacttgt caaaacggtc cgttctagag agttcaaccg cttttacctt
     4741 tgttgtgcta tgcaacgact ctaatcagga gagggttctt gcaactgcct ttgatgttct
     4801 tgatgacgct ggtctcgaag catactttgt tcgctactct gaggaaggtc gcccaagttt
     4861 acgtatccgc gtgcggggaa gctttgacga cacgttcatt cgggtgtttt gcgattcggt
     4921 actctcgcta cgcctcgcga cagatgtcga attcaatctt agacttcccg agtattcacg
     4981 gtatggaggt cccgagtgct ttaaatattt agaatcgttc tggtgtcttg agagcaccca
     5041 actggttaag atgtttaccc gcttatcatc ggataccccc gagcaggtac aaaaagccaa
     5101 aagcaattat atgcgtttcc ttatccagca actggggttc accagacatt acgtatctgc
     5161 cgtagcagaa agctatgaac atgagtttga agcagatcgg cattctatta gaaaagccgc
     5221 cagagctctg cgaagtgttt ttagttccga cgatatgccc gaagtgttta ccgacgaaat
     5281 gcaagaggtt cttgcgcgtt tttcatcctg ccagcttcaa agtaatgctt cagcccaaga
     5341 cgttaagcaa tctattgcac acatgtctgc aaatcgcctt gggcttgatc gtaaagacga
     5401 ggccatattc tggcgggctc ttctcaatca tctaagatcc gcagattttg gaggtgagga
     5461 atgaagacac gtaatgacat tcaacaggag gtgaccctca ttgcaagtaa tctcgaagat
     5521 atcatcccca ttcggtatca agaggctaat cgtacgaaaa gctttaacat taacggaggg
     5581 actcctgccg caattctata tttaagtgtc cttgacgcat tatttcccga tgctggatat
     5641 gatgttcagg ctcacaacta cgcgacaagc atgattttgg aatataaaca taccccaaac
     5701 attggaattg gactgttcgg ggggaccaca ctattggctt ggtgtctgca gtcgatttcc
     5761 cgtggaggaa gcagatatca aggcgcgatt agagaacttg aatcgaggat cgtctttcag
     5821 gcaagacaac aattgacatt tttatcaaac gtgaatgcgc caatatcatc cgaatattac
     5881 gacgttatat ccggactctc tggcgtggtt ttgtatggca tgcgattccg gtccgatggg
     5941 ctgcgattga tttctcggca gatttgcagt agattttgcg aactattagc aacttcgaat
     6001 ttccacgcct tcgggtcttt atcagccact tcgggacagg attccgtggc tcagaagacg
     6061 accaccgact atggttacgc gcatggtatt ttgggagtat tgatgagttg cattctttcg
     6121 gatgtgaacc atgataataa tatggaacca ttcgctgcga taaggcagct tgttgatatt
     6181 tcgaatcact cgagaaacta catacttcca tactcttcct cagattatac tgaaaccgtt
     6241 agtaatggac ggtatgcctg gtgttacggc aacatgccct tctatttttt gtcactaatg
     6301 ctgaaaccgg ttgatccaat aattgcggaa tctctattga atgtcgctat tgctcccctg
     6361 aaggttaata ccagtcaagt acatgatctt ggcgtaatcg gtcttgttga taactctata
     6421 tgccatggcc gagcgggaat agtcctaggg cttcacccct acttgagcca caaggatagt
     6481 cggcctattc gcgatcagct ccttgaagag atcgattgtt ctgttgcgaa tcctattgac
     6541 agtggatttc tcgaaggcga cttgggcacc ttggctgtcc gagtggcact agaatacacc
     6601 gactctattg cgcatctacc ggctttcttt ccttttgttt ctcctacact ttgggaggga
     6661 atatgattgc tagagcatta aatgtgacac tgatctatgg aaaatcgaga aatccagtct
     6721 tgcatagttt gaaccttgaa atcgattcag ggcaagttct tccaatcctt ggcggtaatg
     6781 gaacaggaaa aacgacactg ttgaaagcac tatcggggct acttcgccca cacttgggtc
     6841 gaatcctaat tgatgattcg gatctttatc agaagagagg gagtgcactg cgaaggctct
     6901 cgagctcgct ctactccgaa agatcatttt attatcgctt gtcagcccga gaaaatctcc
     6961 gctatttctt gtcgcttcgt ggcatttatg gcaggactgc aatgtcgtca attgacatgg
     7021 ctctggacag attcgatttg cttggattgc aggatattcc attcatgcac ttatccctag
     7081 ggcaacgaaa gcgactagga cttgcgcgag cgttcgctgc gccagccagt ctctatatct
     7141 tagatgaacc tacggcaaac ctagatgcca agtcatgcag gcttgtctat caagccatga
     7201 cggacaagag cgccgacgga gctagtatac tattctctac ccacaacgtg gccgaccttg
     7261 ctacctccac aggaaatgta atatatctta aaaatgggaa tgcgacacgt gttcatctcg
     7321 agactcgaga ctccattact gcccgcaagc gttttagaat agtcggatct cttgaccctg
     7381 aatccattgc atcaattccc gaagtgtctt gtgtgatttc tcagtccgag gtcgaggttg
     7441 atatacctgt tggtaagtct cttggatcag tgcttcaatc ctttgaacga attgggatcg
     7501 aggtcaacga agtaattgat gaccggagta gataaaatgc attctttttt aatcggcctc
     7561 tacctgtatt tgcggagaga attccttgaa ctcgtaactt ataagctctc cttgatgcta
     7621 ggtgttgttt cagcggttgt tggcatagtt cagtttgctt tcttggctgt ttttctccag
     7681 cagggaaaca gttttccttc attacagaat tatggtggaa gcgtgatggc gtttctggtc
     7741 tctggagcgc tttttactgg ttttatgagt tcttctctct ccagtttctc gcaactaata
     7801 tcctctgagc agcggacagg tacattggaa gctgttttga ctacaccatt ttctattggc
     7861 cgagtgattg catatgctgc ggttagctca tttattcaat tggtaatcgg cacgttttta
     7921 atgatcactt tttttgggat tgcattctct atccccttca acgttaaccc gtggcaactc
     7981 atattggtca tgattctcgg ctacttcaca cttgttggcc tcgggctcgc gggtggagga
     8041 gttcttttgg ttacaaagaa aggcgacccg gtgacatggt tgttgacaac ttttacgaca
     8101 ttattttccg gagtacttta tccggtcgaa attcttccac agtggcttca atcgattagt
     8161 tggtatgtgc caaccacgcg gatattgagt tctctccggg gggcattaac cggctatacc
     8221 agtatgttta tgcttgatgt ggtttacctt atagttgcaa gcatagttag tatgagtata
     8281 ggattgctag tatttagatg gggtctaaac agagctatat gggatggttc cgcgacaagt
     8341 tattaaataa tcatacattt gggatattga agtttgacaa tatggcatag aaaagcgttt
     8401 cttgtcaaat atcatatgaa ctttgggatt gacatactct attagaatat tgtaccagat
     8461 taaggtcatt atttcaaaaa aatgactcta ttctaataga atgtttcctt ctttcgtcgc
     8521 gccaaaagaa acatcaattg taatccgtaa taatttgatg aatacatgat agttcttcca
     8581 atcgtaagat actccgactg gaagaactat catgacggga agcaggtccg acgtccgggt
     8641 cagctcacgg acgattcgta aggaatctca tccgtagtct cggcgacatc ctcatcggta
     8701 tccgcgatat cgctggactg cgccgattct gagtgacggc cgccagcact gttcccgtgt
     8761 ctgaaccggc gggcggcgac cagtcccacg ccgacggcga gcagggtgat tgccgctgcg
     8821 atcacgccct ggatggcggc gccggtatgg gcgagcccgg tccggtagcc gttccagtcg
     8881 tcggtgttgc tgaccacttc ggtgtcgggg cagacgagcc tgccgtcgat cgtgaccgcg
     8941 tcatcgggtg cggacgtctc gtccttgccg tcgaacggat ccgggtcgga gacgacgcat
     9001 tcgaccagcg gcgtgccggt gaccgtggcg cggtcggtgt gatgatcggt cacgcccttg
     9061 aggatgccct tgacctcgac gctctcgccg ggcttgagga cacggctgtc ccaatcggcg
     9121 ggatattcga gatcggtcac ccggccgtcg ccggcgacca gctggtcctt gaggttcagg
     9181 tccttggttc ggtaccatgc gccctgcttg gtgtcggggt cggtggtgct ggtgttggtg
     9241 atagtgaaca cgatgcgcgt gtcgccctgc atggccagcg cgtccttgac ctggtcgcgg
     9301 tcgccggccg gccagccgga ggcctcgtcc catttctcga tcttcaggct cggggtcatg
     9361 tcgggcgtgt gcgtctcgac ctggttggat ggacgtttgg tgccgttgag ggtttcgtcg
     9421 aaccggttgg cgatgtgttc gccggtcttg acgcgcttgc actggatgaa cgcggtccat
     9481 gcctgctcgc tttcgtcgtt gccgctgacg aggtcgagca tgcgctgggt cgcggtaacg
     9541 gtgaccacgc ccttgtcatc ctgcgtaagg gtgaacagtt cgccgccata cacactggcg
     9601 tcgaagccgc tgccggcgat cttcacgccc ttgcgggcga tcaccctgcc ctgctcggtc
     9661 aggtcgcgca tggcgtacac ggcccattgg ccggtgtact ggtcatgctc ggtgtcgagc
     9721 gggtcggtga tgctccagtc ggtgaccttc tggtaggcgc ggtgcgcggg tagcacggag
     9781 ctgtcgaggc ggtagaggaa caggccgttg aggtacacgc tccgcttgtc gatggattcg
     9841 ccgtccacct tcacgaccac gtccttggac gggttgacgg gtttgagggg gttggcgacc
     9901 tcgttggtgt ccttgcgggt gtcgttgacg acctgcgtgg ccttgttctt cacgatatgt
     9961 ccgtcggtga ccttgatgac ggtcatcggc aggctcacct cgtagctcgt gcccagcatc
    10021 gactggtcga tggccggctc cttcaacggg tcgtggtcct tcttttcggc gtattccttg
    10081 aggttcttgg gctgggggtc gcccttgatg gtctcgccgg tggccggcac cttcgtgtcc
    10141 gcggtcttgg cgtacacgta ggcgacgccg tcgatcgccg cgatgttgaa cttcgcggtc
    10201 acgtccttgc cggtcgcggt gtcggtgacc tcgatgcgct tggcgtcgag ggagaggtat
    10261 tcgtcgtccc agtcgtcggt catgccgagt ctccagacct tgtaggcctg gttggtctgc
    10321 ttggcgtcga tggtcacgcg gtagtagatc cggtcgccca gcagcgcggt cttgccgtcg
    10381 atgctgatgg acgggtcggc ctgggtgtcc ttcttcaccg gcgtgaagtc gggcggctcg
    10441 ttccatacct tgttgctcgg ggtgatcatg ttgttcaggg tcagggccca ctggttgccg
    10501 attttggtgt ccgtgggcgc gtccttggcg accgtgccct cgaagcggac gatgatgcgc
    10561 gggttcgcgc cgttgcgcca gttggtcttc acgtacccgt cggagaacac gaggcgcacc
    10621 gcgtgctgcg cgtcgttcca ctgggtctcg tactcggtct tcgggatgaa cctgccggtg
    10681 gacaggtcgg tgacctccag ggtctgcttg tccacttcaa gatgctcgtc ataggtgtcg
    10741 gtgaccgcca cctcgctgac cgagtacgcg agattgccgg gcaggtgggg ctgggtctcc
    10801 agacggtatt ccaagcgttg gcccgggtag acgaccctgc cgtccacgga cgcctggtcg
    10861 cctccctgcg aggattcgcc gaccacgtcc ttgacgacgg gcggtatgta gccgcagatc
    10921 ttcggctcgt tcgtggggat ggtgtgcgtg ttgacggtct gggagccctt gttcgtcagc
    10981 gccttgccgt ccggcgcggt gcagaacgac agttcgtcgc tcgcctgctt gccgaagtcg
    11041 tcgcgcacct ggcccgcgcc cttgccgttg gcgtaggccg ccttgccggg aatgagcagc
    11101 gtgacctgct tcgcggtctt caatcccttc aatccctcgc gataggcccg gcctgcggtg
    11161 gcggtcaccg tggtgccttc catcgtgatc gtccactggt cggtgacgtc cctgccgtgg
    11221 ttggcgatgt cggtgacgct ggactcgcga tcggtgccgg catcggcctc gtacaccttg
    11281 atcttcgact tgtcgtcggc gtcgaacagg tagtcggcgg ccgaccagtc gtccgtgagc
    11341 gtcagggttt ccggggcctg gatgaggttc ttggcgatgg tgccgttgac caccgaggcg
    11401 acccggtccc cgtccagaag cgtcatatcg tcggcgccgg tccggttggt ctccttcggg
    11461 tcgatgaccg cctcccactg gcccttcgcg ttcaggcgga tccagctctt gtcgggattc
    11521 ggccgccacg tatcgaactg tttctttccg gcgtcggcct cgggctcgtg gttccacttg
    11581 ccccacgcat ggtccttgac ctgctggaag tcggagggct tcgacacggt cacgtcgaag
    11641 ctgaactcgt agacatggtc catgggcatc tcgcccttgt ccgccgaacg cgcggccgac
    11701 accgtgttcg acgccttgtc ccaattgatt tcgaactcgc cggaaacgtc gcggttgccg
    11761 tcgatcctgt cgatgagcct gtagttgtcc acggagtatt cgacgccgtt gggttcgatc
    11821 acgtcgcgga aacgcatctc gtagccgccg cggccggtgc cgtacgtgat ggtggtgcgg
    11881 ttcgtcatcc ggtcggcgct cacgccgtcc tcgatcttct tgaccggggg ttcgggcggc
    11941 accgagctca ccttccagga ttcggtcgga tcgcggtccg cggtgtccac ggccgcctgc
    12001 atgcggccct gcttgggtac ctggatgtcg atccagtacg tgccctcggc ccagtgttcc
    12061 atgccgaaat ccttcggcga ggcgagatcg tcgagctggg tatccccatt gctcgggaag
    12121 ctgatcggct tgctcacgct cttcgcgggc aggtaggggc cgttctcgta atggatgatc
    12181 gcggtgccgt tcaacgtctc cctgatcgcg gaaccgccgt tgtcggcgtg gatgacgtcg
    12241 ccgatcgggt cggtggagcc gacctgcatg tcggtcttct gcttgtggct ggtggtcacg
    12301 ttcagcttgt aatcgaccgg cggctggttc tgcgccagca cgatcacgcg gaacgaggcg
    12361 ttcgggttgg agtcgatcga ctcctgtgcc agcgagtcaa cgctgcgcgt gccgagcttg
    12421 tccttccacg tggtcgaggt cgagtacttc tggccctgat acgtgtagtc gcccttcgcc
    12481 tcggccttcc actgcgcctc ccaacggttc ttcgcgttcg agctcacata gctgccgttg
    12541 aacgaaccat ccgccaagcg cacgtagccc accgccacca gacggcagtc cgcgttcccc
    12601 tcacccgtat aggagcgttg gcactcatcg atcgcgtcgc tcaaagtctt gttcatgttc
    12661 acgaactggt tctgcccgtt cgccagatcg gacgacagac gcaccttcgc gtcactcaac
    12721 gccgtcttca tgccatccag cgtggccggc cacgaatcct tgtagatcca atgcacatcg
    12781 gccgtctgcg tcggaccacc gcccgaaccg ccaccgtcct caccggaacc accgccaccg
    12841 ttatcggcca acgctaccgg aaccagacag gccagcaacg ccgcggcggc ggtgatcgac
    12901 gccaccgcac cggcgccctt cttcccgaac ctcatacgaa atcctttccc acatacgaca
    12961 gaagcgcccc tctccgggaa agggaggaga cggggactcc agaacccgcc tcctcccggg
    13021 tccctggaag aaaagcacgc ccgcaagccc gacggccggc cgccggaccc cgaacgcacc
    13081 atcagcatca ccccgcgcca ggtggttctg cggcggacaa cacaacgtac atggcgtttt
    13141 tgtggccaac ggccatttgc gaccattccg ctcatgagtt aaaataggtc gtgaaatatt
    13201 ccattagtac ttgatagcag ggaagcggca ttgaaatatt catctgaaga ttttgtcaat
    13261 ctggacgagg tccacgcact tgcggacgtt ctgaccccaa tcggaccggc actgtacacc
    13321 gttcttgccg aggcgcgttc ggatctggaa accagatatc ccgatgatct gttctggccc
    13381 catcagaacc gacagaatct ttcccgtctt gtcaaccaac gcacggctcg aatttgggaa
    13441 caatatggtt ctgacgattg gacgcttttt gaccggagtg gtttccttca tctgagggaa
    13501 aacgagaccg gcgtgaagct gattctccga aaggtggatc ctctgactca tggagttcct
    13561 aagtcaaatg cgacccgtgc cagccgtgca tacttttcac agagccagtg catcccgaag
    13621 ggacagttgc aagcagtgga tccaggcctg ttcgacgaag gaaagctgat tcccgatctt
    13681 cacgatattg gcttggtgtg cacttgggat gagatgacgg atggaggtgt atccatcgtc
    13741 gtttataaga cagaaggccc ggggcgatac ggcgaaaaga accactatct atttaaattc
    13801 ccgctatttg atagcgttcg tggcgatgag caatatgagt tcattccact acaagaggat
    13861 caggaaaatc ttctgccgaa tttgctggcc gatcagaccg atgtcgaaga tgtggataat
    13921 acagactctt cgtcgtcgga gaaaaatgag aatgaggacg caggcatgaa ttccgacaat
    13981 aaaggaaatg aagctaacta ggaatagcta gtcgtatata gcataaatag atagagagat
    14041 actgcaatgt ccactttcaa tccagaaggg attgcactga agcagcgtct tgctttcaat
    14101 ccagaaagga ttgcactggc acgacgcttg gagggcgtca ctcagaagga gttgtccact
    14161 cgttctggac tatcccaggc aaagctcagc aagcttcaga atggcattat ttcctttaat
    14221 gaatcagatg cggtgaaatt atccggcgct ctagactacc ccatttctta tttcgaggaa
    14281 tctggaacgg ttatcccatt atccgaactt acatatcgaa aaacatccag atcatctatg
    14341 ggtgaattga attcggtttc tacggagtac tcattactca tggatgtaat tcaaaaatta
    14401 tgtcatgtgc tgaagatgaa aaaaaatcca gccgcatgga ttgatgaaat agctccacac
    14461 gaacaatcgc tctccgaaga gaaaatagag agattggcta tccgaacacg tgaatgcctc
    14521 ggattaaagc ctgatggtgc cgttccgaac gtaacccgcg caatcgagcg ggccggaatc
    14581 attgtttctc cgatgagatc attgaatatg cgcggcgggg caaatttgac tagcgaggga
    14641 gtgactgcgc cttcgtcaca gtggcatgcc atgtgtattg gatatttagg taatggtgca
    14701 ttaggaggcg atcgtttacg ctttactaaa gcccatgaac ttggtcatct gatcttgcat
    14761 cgttatcgta aacctgattc accgcaatta gtggagcgtg aagcccatat atttgctgga
    14821 gcttttctga tttcgcaatt agatgctcgc ttggttctta aatccaattt atcgttgcgc
    14881 gattttcttc caattaaggc aggatggggc atttccattg ctgcgcttat ctcacgttct
    14941 cacaatttag gaatcatcga tcggcagagg tacacctccc tcaacataca actatcaggc
    15001 aaaggatgga agaagcaaga acctgtaccc gtcggaatcg agaatccgct attgctgaaa
    15061 cagatgatta catcggcata cggatttaag acagatcaag gactgaaaat agattctatt
    15121 ggcttggcca gtgagttggg agctccattt agatatctag attactggtc cgatggatta
    15181 gatgatgaag gtatgcactg gggtattgcc gccaatcgct ttgagcaaag gcccaatcgt
    15241 atgattgctt aatccttggt tctgtcaaat caactttgac atcggcaaca cgtctggttg
    15301 ttggcgttcc caggaacgcc aacaaccttg ggaaacgaat tgatcattca cgtcgattct
    15361 aatttaacag aacctaattt ctacataggg ttcttccgtt tccctcttga gtaagagtgg
    15421 aagaacccta ttctgatatg gttgaattga tttatactca aatggtaatt taatttgata
    15481 tatacctact caacaaagaa atgaattcaa ttatcggaag caatgatttg tagattagat
    15541 ttttaaggtg tagggccata ctcgtttctc tttactttaa tcattctaat gattttcagc
    15601 aatgtgagta atgatataaa cgatgacggc gccgaagatg ccaatggcgg cgaggattgc
    15661 cagtctggtt tcacggcgtt ccttggccgc catatcggcc tgccggttgg ccagggcttc
    15721 ggcttcggcg gcgacgccgc tggcggcgat ggccgcgatg tgcgcgctca tctggtcttc
    15781 gagcgtggaa tcctcgctcg tgccgtcgaa gggctcctcg ttttcgttgt ggttgtcgtt
    15841 catggttctg ctccgttcct gattgttgga ttgtttgctt tcctgattgt tggcttgctt
    15901 gattgcttgc ttgattgctt gcatgtccga ttgcctgcat gcaatcaagt ttgattgttt
    15961 gattgtctgc atgcgggctt gtttgcttgt cagctttcgt tttgcccggc gaggatggac
    16021 atgcgggcgg cgataagcgc gtggcgcgcg atctccagat agagctggtg gccctcgccg
    16081 tcgccccaga accggtcgaa ctgttcggtc ggcatcatgc tggcggggtc gaacccgttc
    16141 cacacgccgc cgcagaacac cttcgccgcc gcgttcacct cctcgtcgga cggcatgccc
    16201 ggatgcccct ccgcggcgtc cgcggccgcg cgcatctgcg cgccgagcac gcgggcctgc
    16261 aatggcgaga gcgtgtacgc cagtcccgcc gtggagcccg cggggaatcc cgtgttcacg
    16321 ccgagggtga tgacgtgcgc ctcctcgccg atgctgatcc ggtcgccgag cacggagacc
    16381 tccatcgaat agtccatagt gtctcctttc cgcagacgca tcggctttcg ggatcgcgtc
    16441 tgcatgtttg actgcctgaa tgtttggttg ttggcttgtt tgcctgctgg attgtcggat
    16501 tgcctgattg tttgattgtc tgacgggtta cggctcgtcg tcgctgtcga gtcggtcgag
    16561 ctcgcgttcg atggcgtcgc gcaggagctg ctgcatgggc aggtcgtgcg cggcggccgt
    16621 ggtcttgagc cgggtcttga gcgacacggg tatgcgcagt gagagc
//
