LOCUS       c00078_JAHWBM0..       10976 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAHWBM010000004.1 Lactobacillus helveticus strain OSUPECh-4A
            NODE_4_length_46957_cov_793.113375, whole genome shotgun sequence.
ACCESSION   JAHWBM010000004
VERSION     JAHWBM010000004
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2022-06-21 18:01:13
            Original ID  :: JAHWBM010000004.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10976
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10976
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[101:976]"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /neighbourhood="10000"
                     /product="Arginine2putrescine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      102..976
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /neighbourhood="10000"
                     /product="Arginine2putrescine"
                     /protocluster_number="1"
     cand_cluster    1..10976
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /kind="single"
                     /product="Arginine2putrescine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10976
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2putrescine"
                     /region_number="1"
                     /rules="(minimum(3, [AdoMet_dc, Amidinotransf, Arginase,
                     OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /tool="gutsmash"
     CDS             complement(102..299)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_1"
                     /sec_met_domain="Amidinotransf (E-value: 1.2e-18, bitscore:
                     58.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFLAIGISQRTSAAAITDLAHSLFGHSSYDTILAIKIPHNHAMMH
                     LDTVFTMINYDQCTVHPFID"
     CDS             complement(306..641)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_2"
                     /sec_met_domain="Amidinotransf (E-value: 5.1e-26, bitscore:
                     82.9, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVNEMVKQIIAGIRKNEIQNATPSLADLAEDPDYPFYLDPMPNV
                     YFTRDQQAAIGNGMTINRMTFRARRRESLFMETVLKHHPDFKNANIPIWRDRYTHGRLE
                     GGDELIF"
     CDS             complement(791..976)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_3"
                     /sec_met_domain="Amidinotransf (E-value: 3.4e-11, bitscore:
                     34.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLIHVYSEIGKLETVMLHRPGRELENLSPDILNRMLIDDIPYL
                     KIAQKEHDYFAHTLEK"
     CDS             complement(1049..1903)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     71.2; E-value: 1.7e-22)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg78_4"
                     /sec_met_domain="LysR_substrate (E-value: 4.1e-31,
                     bitscore: 99.4, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.2e-22, bitscore: 71.2,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIKQLRYFLVAAEEKQITSAAKRLYIAQPPLSYQLKQLEIELGA
                     QLFKRTAHGIELTDAGQILQSYASEILSLSESVKNQVHKTVSGELGTIAIGMASSSTGL
                     IPMKSFQDLTKFYPEINFDIYEDNTFGIIDKLEKKTIDLGIVRTPYNRNGLNAKTLTTE
                     RMMAVTADPKFKDKTELRIKDLNEQPLIIYRRFEEIFNQTFAHHGIKPFYAVKCDDSRT
                     AITWAKRKMGIALVPESIASTYAPDDLIPIKHSNWITHLQLVWRKDQKVTPLMKRIIDS
                     LSR"
     CDS             2032..4305
                     /locus_tag="ctg78_5"
                     /transl_table=11
                     /translation="MSEKFHGLTQAEADKRLKEDGLNEAPEPEYNFFKEFLSKLWNLSA
                     WVLEGALILECILGKWIQSLFVLLMLLFAAFNGASKKKQSRRVLNTISHKLTPKVAVER
                     DGKWIKIDSKQLVRGDLISLQRGDVLAADVKMVSGKIACDESSITGESKPVKKNIDDTA
                     YAGTTVVEGDGLAIVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFDTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTA
                     DLTGIQDAANLNLLLLDKTGTITENKTAVASWSDLSDLPDKDVLALAGSATDKRNAGII
                     DIAIDEYLKENNIPVMDVEHFTPFTSDTGYSMAEVDGHNVKLGSFKQLSLIDKNTNEAV
                     EGINFKAGRSVAVLIDDKLAGVFILQDKVRKDSKAALAELKKRGVRPIMLTGDNQRTAA
                     AVAEQVDLTGNVISIHDFDESTDIDELAGIADVLPEDKLKMVKFFQEKGYIVGMTGDGV
                     NDSPALKQAEVGIAVSNAADVAKRSSKIVLLDDGLSSIVKILDAGHRVYQRMTTWSLAK
                     LARTAELTMLLTFGYLFFNYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     RLAKIAFSLAAGWTVIGIAFFSYLNMHGWSHNSISTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGIVQIADVALTFILALCGLAMAQISWQNLLITVVVALIAAIIIDLIYQPV
                     MKNR"
     CDS             complement(4373..4873)
                     /locus_tag="ctg78_6"
                     /transl_table=11
                     /translation="MMRKQIISAAGIMLAVIGLGAATTQSVDAVVTNPVRQGERLNLTR
                     NATVYNRHGVKVGHLRKGKLYKVRAIKVINGNTYVKIRKNRFVKEEAFLPYMKTTVKVV
                     NRIKKHSFVYDENGEKIPGKFLKRGAKVNYLGHKEINEKPFIKIADGEYVKALNALTTV
                     TNH"
     CDS             5012..6205
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg78_7"
                     /sec_met_domain="PLDc_2 (E-value: 1.5e-16, bitscore: 51.9,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILTWDIIRRTIEVLWIINIAFAVWTVFRSRRSVVATWAWMLVLT
                     VLPGIGFILYLFFGRQLSHDEIFAIQEEQKKVQRHYLAEQRDMLKEHDLLPEKERLPRV
                     RMLSELNLNNDDAILTFDNQVKVFISGPELFDQMITDIKNAKKSVSLEFYTFYSNQLGH
                     RVLKALEEAAANGAKVRVIYDTSGSRGTKPSFFDHLRELGGEAQPFISTSKKHWFTTPR
                     LNYHLHRKLVIIDHHIGYIGGFNIVDQYVNKSPKFGHWRDTHLRVIGQSPILMEVRFAM
                     DWNTSIRRTNLPKFELKELKPFTVNRKDINDNKNVAMQLFPQDLIINITASDEAEGIIA
                     GAKKYIYIQTPYLIPEESILEALIIAANSGIDVRIMWFLACPIIHLFIVLQNTMLSI"
     CDS             6151..6501
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg78_8"
                     /sec_met_domain="PLDc_2 (E-value: 2.3e-16, bitscore: 51.3,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDHPFVYRATEYYAKYLVAHGVKVYKYNDGFIHAKTMVSGSNIS
                     SVGSANQDFRSYTLNFEVNSFNYNPALTQELKKIFEKDLDKCTLLTNDYFAQQSSWLKF
                     KQYFSRLLSPIF"
     CDS             6629..6952
                     /locus_tag="ctg78_9"
                     /transl_table=11
                     /translation="LANRVKIGVLNLMHDKLDTQQRFARVLPDADLTFFYPRMHYQNRP
                     VPPEVAKTSQPLDLNQIKEFDGFIITGAPLDHLDFDQVTYIEEVRCLLQLLDKYKLQQL
                     YFC"
     CDS             6959..7423
                     /locus_tag="ctg78_10"
                     /transl_table=11
                     /translation="MAALDYFYNIQKRILSKKIFGVFPHLIIEPHPLLNGLSKGFIAPH
                     ARYAEMDKTQIMQDPRLTINSVDDNGHLFMVSSLEKPEQNFIFSHIEYGRKGLKKEYER
                     EIAAHPERHYKKPENYSLSNLLFQWKDTQKTFFNNWLTQVKKSKLVLLDK"
     CDS             7439..8368
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg78_11"
                     /sec_met_domain="PALP (E-value: 1.8e-68, bitscore: 222.5,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTIYNSVTELIGNTPLLKLNRVVPNDAADVYVKLEFENPAGSIK
                     DRIALAMIEKAEREGNLKPGGTIVEPTSGNTGIGLAMVAAAKDYHIIIVMPETMSVERR
                     KLMKGYGAELILTPGADGMKGSIAKAEKLVKEKGYFMPMQFENTENPNIHELTTGPEII
                     AAMNGIGKSVDAFVAGVGTGGTLSGIGHALRRENPSTKIFALEPTESPLLKDGKTGKHG
                     IQGIAAGFIPKNLDKDIYDDIITVSTDEAMATAREVAKNEGFLPGISAGANIHGAIEIA
                     KKLGKGHAVVTVVPDGGDRYLSTALFNA"
     CDS             complement(8512..9039)
                     /locus_tag="ctg78_12"
                     /transl_table=11
                     /translation="MAIDFSKYIASVKDFPNKGIVFRDITPILQDGELYRIATHELAEY
                     AKSRKADVIVGPEARGFIVGCPVATELGLGFVPARKPHKLPREVERASYDLEYGSNSLE
                     MHKDAIKPGQRVVLCDDLMATAGTLRASKELIENLGGKLVGAAFYIELPDLKGREKLPD
                     VDIYSLVQYHGA"
ORIGIN
        1 ttatatcaaa catatgttta agaaagaagg ggggaacaag caaaaaaact aaaaaaggcc
       61 ggattcatca cgggattaaa atcccgtgtt ttcttcggca attaatcaat aaaaggatga
      121 acggtacact gatcataatt aatcattgta aagactgtat ccagatgcat catggcatga
      181 ttatgtggta ttttaattgc taaaattgtg tcataactag aatgaccaaa caggctatga
      241 gcaaggtcag tgattgcagc agcggaagtt ctttgagaaa taccgattgc taaaaacatg
      301 attgtttaaa aaatcagctc atcgccacct tctaaacgtc catgagtgta acgatcacgc
      361 caaataggaa tattggcatt tttaaagtcg ggatgatgct ttaaaacggt ttccataaat
      421 aatgactcac gtcttctagc tctaaatgtc attctattaa tagtcatgcc attaccaata
      481 gctgcttgtt gatcacgagt aaaatacaca tttggcattg gatccaaata aaatggataa
      541 tctggatctt cagctagatc ggctaatgaa ggagttgcat tttgtatttc attttttcta
      601 ataccagcaa ttatttgctt aaccatttca tttactggca ttgctattaa atagtctatc
      661 agtaattgat gtaatggatc ttctttttta tattggattc ttctaataat tgatctacaa
      721 attttgtacg gacatcttca ttagtcaaag agtgagctaa taaatcttct aaataaacga
      781 catgaactcc ctatttttcc aaagtgtggg caaaatagtc atgctctttt tgagctattt
      841 ttaaatatgg aatatcgtca attaacattc gatttaagat atccggtgaa agattttcta
      901 attctcttcc cggtcgatgc agcataactg tttctaattt gccaatttcg gaataaacat
      961 gaattaagtc agtcattata gcgtctccta attcaaatta tgtatccgct tacaatgatt
     1021 atggatcaat taggtagaag ttacaatctt aacggcttag tgaatctatt attcttttca
     1081 ttaaaggcgt caccttttga tccttgcgcc acactaattg caaatgcgta atccaattac
     1141 tatgtttaat aggaataaga tcatcaggtg catacgtaga agcaatagat tcaggaacaa
     1201 gagcaatccc catttttctc ttcgcccaag taatcgctgt tctagaatca tcacatttaa
     1261 cagcataaaa cggcttaatc ccatgatgag caaaagtctg gttaaaaatt tcttcaaatc
     1321 ttcgataaat aatgaggggc tgctcattta gatctttaat ccttaattcc gtcttatcct
     1381 taaatttggg atcagcagta actgccatca ttctttcagt agttaaagtt tttgcattta
     1441 agccattacg attataaggc gtacgcacaa ttcctaaatc gattgtcttc ttttccaatt
     1501 tatcgataat gccaaaggta ttatcttcat aaatatcaaa gttgatttcc ggataaaact
     1561 tagttaaatc ttgaaaactt ttcataggaa ttagtccagt tgatgatgaa gccatgccta
     1621 ttgcaatcgt gcctagttca cctgaaacag ttttatgaac ctgatttttc acgctttctg
     1681 ataaagagag aatttcacta gcatagctct gcaaaatttg tccagcatct gttaattcaa
     1741 ttccatgagc agtacgctta aataattgtg ctcctaattc tatttctagt tgctttaatt
     1801 gataactcag cggcggttgt gcaatgtata gtcttttagc tgctgaagtg atttgctttt
     1861 cttcggctgc tactaaaaag tagcgtaatt gtttaatatt cattaataat ttatcttttt
     1921 tattttagtt gtatctctta ttaaaaattt ctatatctta tattttaatt tagtattttc
     1981 attcaaacaa catatgtgct actttattaa ggtagatttg gagggaataa aatgtctgaa
     2041 aaatttcatg gcttaactca agccgaagca gataagagac ttaaggaaga tgggttaaac
     2101 gaagcacctg aacccgaata caactttttt aaggaatttc tatcaaaatt atggaatctt
     2161 tctgcctggg ttctagaagg tgccttaatc ctcgaatgta tcttaggcaa atggattcag
     2221 tctttgttcg tcttgttgat gcttcttttt gcggctttta acggtgcatc caagaagaaa
     2281 cagtcacggc gggtattaaa taccatttca cataagctaa cccctaaggt ggctgtagaa
     2341 cgcgatggta agtggatcaa aattgactct aagcaattag ttagaggcga cttaatctca
     2401 cttcaacgtg gagatgtact tgcagccgat gtaaaaatgg ttagcggtaa gatcgcctgt
     2461 gatgaaagct caattaccgg tgaatctaag cccgttaaaa agaacattga tgacacagct
     2521 tatgctggta ctactgttgt tgaaggcgat ggattagcaa ttgttactgc aactggtaaa
     2581 gattcaagaa gtggtaagac cattaacttg atcaacaatt cagctgcacc tggtcacttg
     2641 caacaacttt taactaagat tatttactac ctttgcctac ttgacggtgt acttacctta
     2701 gttattatca ttgcttcatt ctttaagggt ggtaattttg atacgtttat caacatgttg
     2761 ccattcttag ccatgatgtt catcgcttca attccggttg cgatgccgtc aacctttgca
     2821 ttgtccaatt catttgaagc aacccgttta agtaaagaag gcgtcttaac agctgattta
     2881 actggtatcc aagatgcagc taacttaaac ttgcttttac ttgataagac gggaacaatc
     2941 actgaaaata aaactgcagt tgctagttgg agcgatttaa gcgatttgcc agataaagat
     3001 gtacttgctt tagccggtag tgcaactgat aagcgcaatg caggtatcat tgatatcgcc
     3061 attgatgaat acttaaaaga aaacaatatc cctgtcatgg acgttgaaca ctttacccca
     3121 tttacttctg acactggcta ttctatggct gaagtagatg gtcacaatgt taagttaggt
     3181 tcatttaagc aactttcatt aatcgataag aatacaaatg aagcagttga aggcatcaat
     3241 tttaaagctg gacgctcagt tgccgtgtta attgatgaca aacttgcggg agtatttatc
     3301 ttacaagata aagtaagaaa ggactctaag gctgctttag cagaacttaa aaaacggggc
     3361 gtacgtccaa tcatgttaac tggtgataat caaagaactg ccgcagcagt cgctgaacaa
     3421 gttgatttaa ctggtaacgt tatctctatt catgactttg atgaaagcac cgatattgat
     3481 gaattagcag gaattgccga tgttttacct gaagataaac ttaagatggt taaattcttc
     3541 caagaaaaag gttatatcgt tggtatgact ggtgatggtg ttaacgactc tcctgcttta
     3601 aagcaagctg aagttggtat tgctgtttct aacgctgccg atgttgccaa gcgttcaagt
     3661 aagatagtgc ttctagatga tggcttaagc tctattgtta aaattcttga tgctggtcac
     3721 cgtgtatatc aacgaatgac tacttggtca cttgctaagc tcgccagaac cgccgaatta
     3781 actatgcttt taaccttcgg ctatctcttc ttcaactata ttccaatggc attaaatgct
     3841 atggttattt acacaatcat gaataacatg gttaccatga tgattggtac cgaccgtacc
     3901 catattactt acaaaccaga aaattggaat atggcaaggt tagccaaaat cgcattctct
     3961 cttgctgcag gttggacagt tatcggtatc gcttttttca gctacctcaa catgcatggc
     4021 tggagtcaca attctatctc taccatggtc tatgtttact tagttctaag tgcaatgtta
     4081 attgtattaa ttactagaac tcgtaaatac ttctggcaag attacccatc taaacttgta
     4141 ggtattgttc aaattgccga tgtcgcatta acctttattt tagctttatg cggtttagca
     4201 atggctcaaa ttagttggca aaacttatta attaccgttg tggttgcatt aattgcagca
     4261 attattattg atttgattta tcaaccagta atgaaaaaca gataattaac ttaaaacaaa
     4321 aacactctga aaactacatt gtagtaatgt agttttcaga gtgttttttt gattaatgat
     4381 tagtaactgt agtcaaggca ttcaaagcct taacatattc accatcagca attttgataa
     4441 atggtttttc attaatttct ttatggccta aatagttaac cttagcacca cgctttaaaa
     4501 atttgcctgg gattttttca ccattctcat cataaacaaa agaatgcttt ttgattctat
     4561 taactacttt tacagtagtc ttcatatatg gcaagaaggc ttcttcctta acaaatctat
     4621 ttttacgaat ctttacataa gtattaccat taattacttt tatggcacgt actttgtaaa
     4681 gctttccctt tcttaaatgt ccaactttaa caccatgtct attataaaca gtagcatttc
     4741 tagttagatt taatctctca ccttgtctaa ctggattagt aacaactgca tcaacgcttt
     4801 gtgtagttgc tgcgcctaat ccaataactg ctaacattat acctgcagca gaaataattt
     4861 gttttctcat cataatccac ccccgtagtg tttataccat tctccatccc ttattttatc
     4921 aaaaattatc gaattggaag cattttttac tcatctgttt tataactatt tgcttaattc
     4981 tgctaaaatt atttataaca ctacttaatt catgatttta acttgggata taatccgtag
     5041 gactatcgaa gtcttatgga ttatcaatat tgcgtttgct gtatggacgg tctttagaag
     5101 tcgccgcagc gttgttgcaa cttgggcatg gatgcttgta ttaaccgttc tgcccggtat
     5161 cggttttatc ctatatcttt tctttggtcg tcagctttca catgatgaaa tctttgctat
     5221 tcaagaagag caaaaaaagg tacaaagaca ttatttagct gagcaacgcg acatgcttaa
     5281 agagcacgat cttctacctg aaaaagagcg tcttccacga gtaagaatgc tttcggaact
     5341 aaatcttaac aacgatgatg cgattttaac ttttgataat caggtcaaag tatttatttc
     5401 tggaccagaa ctttttgacc aaatgattac tgatatcaaa aatgccaaaa aatctgtcag
     5461 cttagaattt tatacttttt attctaacca attagggcat cgtgttttaa aagccttgga
     5521 agaggctgca gctaatggtg ctaaggtaag agtaatttat gatacctctg gatcaagagg
     5581 cactaagcca agcttttttg accatttaag agaattgggc ggcgaagctc agccatttat
     5641 ttccacttca aaaaagcact ggtttactac cccacgactc aattaccact tacatagaaa
     5701 attagttatt attgaccacc atattggcta tattggcgga tttaatattg tagatcaata
     5761 tgtcaataaa tcaccaaaat tcggtcattg gcgggatacc catttacgtg taattgggca
     5821 atcaccaatt ctaatggagg tccggtttgc aatggactgg aacacgtcaa tcagaagaac
     5881 aaatttacct aaatttgaat taaaggaact taaaccattt actgtcaatc gaaaagatat
     5941 caatgataat aaaaatgtcg ctatgcaatt gtttcctcag gacctgataa tcaacattac
     6001 ggcatcagac gaggctgagg gaattattgc aggagctaaa aaatacattt atattcaaac
     6061 gccttattta attcccgaag aatcaattct tgaagcctta attatcgctg ctaacagcgg
     6121 tattgatgtt cgaattatgt ggttccttgc atgcccgatc atccatttgt ttatcgtgct
     6181 acagaatact atgctaagta tttagtagcc catggcgtta aagtatacaa atataatgat
     6241 ggttttattc atgcaaaaac tatggttagc ggttctaata tttcttcagt tggttccgcc
     6301 aatcaagatt tccgaagcta tacattaaac tttgaggtaa actcattcaa ctacaaccct
     6361 gctttaactc aagaattaaa gaaaattttt gagaaggact tagataaatg taccctttta
     6421 actaatgact actttgctca acaatcatca tggttaaaat ttaagcaata cttctcaaga
     6481 ttattatcac ctatttttta atgaaaagcc ctctatcggt ttatccgata gggattttac
     6541 tttgtatttt aaaaatgcag ttttatttct ttacttattt tttataggtt atataatgat
     6601 aactattaaa aagtaaggag gataaaactt ggctaataga gtaaaaatag gcgttttgaa
     6661 tttaatgcac gataagttag atactcaaca aagatttgca cgcgttttgc cagatgcaga
     6721 cctgactttc ttttatccac gtatgcatta tcaaaatcgt cctgtcccac ctgaagttgc
     6781 aaaaacttcc cagccattag atcttaatca aatcaaagag tttgatggct ttatcattac
     6841 gggcgcacct ttagatcatc ttgattttga tcaagttacc tacatcgagg aagtccgatg
     6901 tttgctccaa ctattagata aatacaagtt gcagcaatta tatttttgct agggtgcaat
     6961 ggccgcttta gattattttt acaatattca aaaaagaatt ttatcgaaaa aaatctttgg
     7021 tgtttttcct catttaatta tcgaaccaca tcctttatta aatggactca gcaaaggatt
     7081 tatcgctcca catgctcgtt acgctgaaat ggataaaaca cagattatgc aagatccacg
     7141 attaaccatt aattcagttg acgataatgg gcatctattt atggtctctt ctttagaaaa
     7201 gcctgagcaa aattttattt tctctcatat cgaatatggc cgaaaaggcc ttaaaaaaga
     7261 atatgaaaga gagattgctg cacatccaga gcgacattat aagaagccag aaaattattc
     7321 attatcaaat ctattgtttc aatggaaaga tactcagaaa acatttttca ataactggct
     7381 aactcaagtt aaaaaaagca aattagtatt attagataaa taaaacgagg catacattat
     7441 gtctacaatt tataattcag ttacagaact tatcggcaac actccattac ttaagttgaa
     7501 tcgcgttgta cctaacgacg cggcagatgt ctatgtaaag ttagaatttg aaaacccagc
     7561 tggttcaatt aaagacagaa ttgctttagc tatgatcgaa aaagctgaac gtgaaggcaa
     7621 cctaaagcca ggtggcacaa ttgtagaacc tacttcaggc aataccggta tcggtttagc
     7681 catggttgct gcagctaagg actatcacat tattattgtt atgccagaaa ctatgagcgt
     7741 tgagcgtcgt aaattaatga agggctatgg tgctgaactt attttgacac caggtgcaga
     7801 cggtatgaag ggttcaattg ctaaggccga aaaattagtt aaagaaaaag gctacttcat
     7861 gccaatgcaa tttgaaaata cagaaaatcc taatattcat gaattaacta ctggtccaga
     7921 aattattgcc gcaatgaatg gtatcggcaa atccgttgat gcctttgttg ctggtgttgg
     7981 tactggtggt actttatcag gaattggaca tgcacttagg cgtgaaaatc catccactaa
     8041 gatatttgca cttgagccaa ctgaatctcc actcttaaaa gatggaaaaa caggtaaaca
     8101 tggtatccaa ggtattgccg caggtttcat ccctaagaat ttagataagg atatctacga
     8161 tgatataatt acagtttcta ctgatgaagc aatggctaca gctcgtgaag tagctaaaaa
     8221 cgaaggcttc ttacctggta tttcagctgg tgcaaacatc catggtgcaa tcgaaattgc
     8281 taaaaagtta ggcaagggac atgctgtggt tactgtagtt ccagacggcg gtgatcgtta
     8341 cctttcaact gcattgttta atgcttaaaa cttaatttct gtaaacaaat actcctaagt
     8401 aaaatttcct taggagtatt atttttattt ctgttgattg tgcaccagtc aatgttggta
     8461 caacactttt agtataatga cctttactaa ttagatcaat attgaattta tttaagcacc
     8521 atgatattgc actaagctgt aaatatcaac atcaggcaac ttttctctac cctttaaatc
     8581 aggcaattca atgtaaaatg cagcacctac aagcttacca ccaagatttt caattaattc
     8641 cttagaagct cttaaagtac ctgcagtagc cattaaatcg tcacagagaa caactctttg
     8701 gccaggctta attgcatctt tatgcatttc aaggctattt gaaccgtatt ccaagtcata
     8761 tgaagcacgt tcaacttctc ttggcaactt atgtggcttt cttgctggaa caaaacctaa
     8821 gcctaactca gttgcaacag gacagcctac aataaaccca cgtgcttcag gacctacgat
     8881 tacatctgcc tttctactct ttgcatattc tgccaattca tgagtagcaa tacgatacaa
     8941 ttcaccatct tgcaaaatag gtgtaatatc gcgaaagaca attcccttat taggaaagtc
     9001 cttaacactt gcaatatatt tactaaaatc aatcgccata agaagaaaaa cctccataat
     9061 tctgtgcgtt tgtattcaaa cacttttgac ttgtatattt taccaaagat ttgttataaa
     9121 agtactgaaa tcttgatatt tatctatctt tttaccaaat tattaacata tgtaattaat
     9181 ttttgagtag gcatcgttct tagttgatta ataaatttaa tttgtgaact cgttgccatt
     9241 aaatatttag aagctgtcaa tggttgcttc tttggattag actcaccaac taatttttga
     9301 tcgtctaatt taacaaaacc taattcaaag aatactcgca aaataaacaa tacactatca
     9361 taatccaaac ctagatatgg tgctacagtg cgatagtctt caggctttaa tgctggatgg
     9421 gcataaatat actttaacac ttttccgaaa taactctttg ctggaatttg ttcaacaggt
     9481 aactgatcta ataaaaagca taaataaatt tgttgataat ctttttttaa agctgcattt
     9541 aattccactt gattgcgagg cacatcaagc aaagctactg tttcacccga ttgatcataa
     9601 tctttaacca agctaatttt atcatcatca atttgaaggc tattcttaac aattggaata
     9661 ttctttttgt caaaaagcaa ataacgatct gcaaggccca tgacaaattt ctcttgtctt
     9721 aaatcaatta ctgatgttgg cacagctaat tttggggatg caaaggctat tccttccatg
     9781 atgccttgca aagatacttg tttgcgataa gtattcaaag agagagtaac aaagattttt
     9841 gaaataaacg gtaacaaatt attattcaaa taatccttat taaatcccac aattgctaaa
     9901 ttgccgtctt ttttattagc tgttaattta acatgattct tatcttttcc tattttgaaa
     9961 aagtgtgtaa tagttggatc cgaaatacta aaaattggct gcggatcacc agtaccaaat
    10021 ggtcccactt gattaatttg agccaaagtt tgaggtgata agtcatgcat aggcaattcc
    10081 atatcgtact ctttagtctc taaaccaccg tcaacatgaa aatcggcttc aaactttttc
    10141 cgtaggtcat ttactttgtc ttcttccatg gataaaccac aagcaaaatc atgacctcca
    10201 aatttggtca atagactttc ttttaacgga ttaagagcat caaataagtt aaaaccactg
    10261 aatgaacgac ctgatccctt aatctcccct tcatcgtttt tagttaaaac aattgttggt
    10321 ttatgcagtt tttccactat cttgttagca acaagcccca aaactccttc atgaaaatca
    10381 ggatcatata aaactaaagt attttgcttt tgccaactat tttcacgaac taattccatg
    10441 cagcgatcgt aaacctcagt agttagctct ttacgcttat tatttaagtc ttcaatctga
    10501 tctgcgatct tctgtgcctc aagatcatca tcactaagca aaagctctac tgccagatta
    10561 gcattagcca aacgtccaac agcattaagt ctaggagcaa tattaaagcc tacatctgtc
    10621 tcattaatcg tttctagcgt taaaccggca tttttgataa gcgctcttaa gcccggtcgt
    10681 tcggtttgat taagaacatc taacccacgt tttacaataa tatggccttc accagtaact
    10741 ttaaccatgt caccaatagt accgatcatt gctaaatcta gcaattctgg tacaggatcc
    10801 tgcataagct cacgacaaat cgtataagct acacctgcac cacaataatc atcaaaagga
    10861 tattcttgac caggataatt acagtgaaca attgcataag catctggctt attttcttga
    10921 aaagtatggt gatccgtaat aatagtatca acgccatgtt ctttagcgta ttcaac
//
