LOCUS       c00026_JAHBRI0..       14181 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAHBRI010000026.1 Streptococcus thermophilus strain Brie1 Contig_26,
            whole genome shotgun sequence.
ACCESSION   JAHBRI010000026
VERSION     JAHBRI010000026
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 01:19:52
            Original ID  :: JAHBRI010000026.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14181
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14181
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[231:9181]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      232..9181
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..14181
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14181
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(232..486)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2e-14, bitscore:
                     46.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENLNTLDLETLASVEGGGCSWGGAGGATVQGAIGGAIGG
                     AFGGNVVLPVVGSVPGYLAGGVLGGAGGTVAYGATCWWS"
     CDS             complement(737..1138)
                     /locus_tag="ctg26_2"
                     /transl_table=11
                     /translation="MKLKNISSSVLRSFRTITAALAVFLISISLSLYKSKISPGTWLTV
                     GALAFVVIFVNGLLYRMLKKRPDSVNLLTIRQSFIVFPVITFLVLSVEFYTLLTFSDTT
                     DRIVLAVLMLLLILCDFLSYLQVKKYFKQ"
     CDS             complement(1468..1635)
                     /locus_tag="ctg26_3"
                     /transl_table=11
                     /translation="MFKNSKPYLLATILIVMGLANLFRSLDAVHHTINLLGLTVLLYSL
                     LFKKWVQFQK"
     CDS             complement(1732..1947)
                     /locus_tag="ctg26_4"
                     /transl_table=11
                     /translation="MIENFDIREELFVIMTKKRLVSLMMSMGFVLVALHNFGEKLNFGL
                     QCLNLIGLCLFLFLMCTVIKDIRSDK"
     CDS             complement(2143..2373)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_5"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 9.2e-19,
                     bitscore: 60.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENFNTLDLETLASVEGGVCSWGGFAKQGVATGVGNGLRL
                     GIKTRTWQGAVAGAAGGAIVGGVGYGATCWW"
     CDS             complement(2548..2703)
                     /locus_tag="ctg26_6"
                     /transl_table=11
                     /translation="MKKYLIIFSTIAMIYLYSKVLLSSGNIYQLLLASIGFFFFLFGVY
                     RQYRKN"
     CDS             complement(2729..2929)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_7"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 9.8e-09,
                     bitscore: 28.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNKQLERFKKLDTNALSNVSGQGYGAQCVIGTTGMTIVGAAFFG
                     IAGAGAGFAGGSTAFCYDTAK"
     CDS             complement(2948..3124)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_8"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.4e-11,
                     bitscore: 37.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENFNTLDLETLASVEGGLSCDEGMLAVGGLGAVGGPWGA
                     VGGVLVGAALYCF"
     CDS             3380..4111
                     /locus_tag="ctg26_9"
                     /transl_table=11
                     /translation="LKIYLLEDNSIQMGRLEEAVAHELKSFGKDLSCVQSFDKPDQLLS
                     AITSNTSDQIFFLDIEIKGEDKKGLDIAKIIRQNNPYAIIAFVTTHIEFMPQAFGVTAY
                     KYINKTLDEASFRKEIGETIAQVFPINATTTDEFFLYKTESQLINLPMDQILYLSTSDI
                     KHHVHLQTIHTLMDIRANLADFKKIHKKLYPCHRSYIVNTDMIISVNKTNYEATLINGQ
                     VLPVSRMKIGKIAQIVEERGR"
     CDS             4108..5451
                     /locus_tag="ctg26_10"
                     /transl_table=11
                     /translation="MMLTTLWLLFLTLLSAGLEIILFLYLMGQKIRLRYFFLLLIFNLA
                     FNFIYNHSSWFIIKFWGEDIYYLLLSFLLSTKTKKPLKIKIFNGLFPDILNNLSLRLIT
                     FFIFPFFNISITDYKSSLLISIPSSIAPLCLSFLFIKLFKESFTILQKQKSNSPIQHII
                     IVANFFMFGYTLLLQSLMYLENTTHSSTLELRKLCIVISLVLFFIMIVFLERNIREMIQ
                     GQLDFQKNLQLENLYTYNKHIECLYNSVRSFRHDYSNLLVTLRLGIDKDDMDIVKEVYD
                     SVLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGM
                     ETLDFIIVTSIFLDNAIEGAIQTQNPKITISFWEDHCSQLLSISNTISEEKTETKTIFE
                     RGVSNKGRERGIGLANVTEILDNYINVNLETQSNNFSFTQQLTITKKA"
     CDS             complement(5469..5630)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_11"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.6e-08,
                     bitscore: 27.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANNTINNFETLDNHALEQVVGGSGWMDYINGFLKGFGGQRTLPT
                     KDYNIPQA"
     CDS             complement(5645..7012)
                     /locus_tag="ctg26_12"
                     /transl_table=11
                     /translation="MNPQLFKSTEFYHRRYHNMSTVLITPLILLVIFLFLFAFFAKKEV
                     TVTSRGSIEPTKVIAVIQSTSDNTIIDNQLVANKVVKKGDTLVQYSETMEASQKEGLQK
                     QLELLKRQESGLKTLQSSLTQGTNLFQEQEDEFGYQSTFNTYLSQAQDIDLGVAKTNTE
                     VNNQAAIASNTGSAIDNQISQLQTQVSEYEALSQAITNHETTLPEGNPHQATLNAYNSQ
                     YATTPDASVTDQYLSQVNTNISSLNASIGNLEIQKAGTGTVVTYDNSDSTKKEALKNQF
                     LQNAGQQLSSVETQINDTESKINQADVLLTNTLIQSPEDGILHLSQADKKATMAATGTE
                     LAQLYPDMTQTQEVAITYYVNSDYVPKLQKGQSVRLTLDKVGNHGTTIIGKLESIDNSA
                     TETERGNVFRVTARASISEKEAQNLRYGLEGRVTSVIDQKTYFNYFKDKLLNLQDQ"
     CDS             complement(7028..9181)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 306.8; E-value: 5e-93)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_13"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1103.5,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 5.7e-45, bitscore:
                     145.1, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRFRRTFVPQIDMRDCGVAALASVAKYYGSDYSLAHLRELAKTN
                     KEGTTALGLVEAAKKIGFETRAIKAEMSLFEMEDVPYPFIAHVNKDGKLQHYYVIYKST
                     KDYLIIGDPDPSVKVTKMTKERFEKEWTGVTLFMGPEPSYKPHKDKKNGLWDFLPLIFK
                     QRSLIANIVFASLLVTLINILGSYYLQGILDEYVPNQMKSTLGIISIGLVVTYVLQQMM
                     TFARDYLLTILSQRFTIDVILSYIRHIFELPMSFFATRRTGEVISRFSDANSIIDALAS
                     TILSLFLDFSIVIIVGGVLLIQNSNLFKLVLCSVPIYTLIVFAFMKPFERMNHDVMQSN
                     AMVNSAIIEDINGIETIKSLTSEEVCYQKIDGEFIDYLDNSFRLSKLSILQTSLKQGAQ
                     LILNVLILWTGAQLVMGNTISIGQLITFNMLLSYFTNPLENIINLQTKLQSAKVANTRL
                     NEVYLIESEFGQSDDTYQEGIADGDITVTDLSYKYGFGRDTLTDVSLTIRQGEKISFVG
                     VSGSGKTTLAKMLVNFYQPYKGHIDFNGQNISRIDKKTLRQHINYLPQQSYIFSGSVLE
                     NLTLGAARGITQADILKACEIAEIRQDIENMPMGFQTELSDGAGLSGGQKQRIALARAL
                     LTKSPVLILDEATSGLDVLTEKQVIDNLLALKDKTIIFVAHRLSIAERTDRIVVIDHGR
                     VVETGSHQDLMSYPGFYYQLFRK"
     CDS             complement(10195..11940)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     284.6; E-value: 9.7e-87)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 309.1; E-value: 1e-93)"
                     /gene_kind="transport"
                     /locus_tag="ctg26_14"
                     /transl_table=11
                     /translation="MPNQNQWSVFKRLLTYLKPYKFLTFLALTFLLSTTVIKSIIPLVA
                     SYFIDHYLHDMNQAASMILIGYYGLYLLQTLVQYLGNLFFARVSYSIVRDIRRDAFANM
                     EKLGMSYFDKTPAGSIVSRLTNDTETISEMFSGTLSSFISAIFIFVTTLYTMMILDIRL
                     TGLIVLFLPLIVLLVNLYRKKSVAIIEKTRALLSDINAKLSESIEGIHIIQAFNQEKRL
                     KKEFDAINEEHLIYASRSISLDSLFLRPAMSLLKLLAYAVLMAYFGYRGIYLGITAGTM
                     YAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPEQRDTAAKVTEGNI
                     RFENVSFSYDGKHQILDNISFSVNKGETIAFVGSTGSGKSSIINVLMRFYEFQSGRVLI
                     DGVDIRDYSQAELCKNIGLVLQDPFLYHGTIKSNIAMYQDLTDEEIKAAAEFVDANHFI
                     DKLPEGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANIDSETEAIVQNS
                     LAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIEHGSHEELLALGGTYHKMYSLQAG
                     AMEGE"
     CDS             complement(11933..13690)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 389; E-value:
                     6.4e-118)"
                     /gene_kind="transport"
                     /locus_tag="ctg26_15"
                     /transl_table=11
                     /translation="LFFKESIIAKLWWFFKLEKRRYIVGILALSLVSVLNLIPPMVMGR
                     VIDAITSGKLTNQILLLNLVYLLLAALGMYYLRYVWRMYILATSYRLGQIMRSRLFEHF
                     TKMSPSFYQKYRTGDLMAHATNDINSLTRLAGGGVMSAVDASITALVTLITMFFSISWQ
                     MTLMAVLPLPFMAFATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQEA
                     ELQSFQETNKMTFEKNMHTMKYDSLFDPLVLLFVGSSYVLTLLVGAFMIQAGQITVGNL
                     VTFITYLDMLVWPLMAIGFLFNITQRGNVSYQRIETLLEQESDVQDPAYPLPSIENGRL
                     DFAIDRFAFEDEDTLRDIHFTLDKGQTLGLVGPTGSGKTALVKLLLREHDVNQGAIYLN
                     GHDIRDYRLSDLRSLIGYVPQDQFLFASSILDNIRFGNPDFSIDKVEEATKLAQVYDDI
                     KDMPEGFETIIGEKGVSLSGGQKQRLAMSRAMILNPEILILDDSLSAVDAKTEHAIIDN
                     LKHTRKDKTTIITAHRLSAVVHADLILVMQDGRIIERGRHDDLLAQGGWYAKTYESQQL
                     EMEGGEAHA"
     CDS             complement(13878..14084)
                     /locus_tag="ctg26_16"
                     /transl_table=11
                     /translation="MRERGQVWSYSEVKRESQLANYNTDGRYLSETTNFELYNFVREYK
                     TSDEIRRIWNPKKDESVIHDKDN"
ORIGIN
        1 acatctattt ttacaatcat caacgttttc aagagcgcaa taacggcctt gcccctcttg
       61 aaatgaggaa caaggccgtc gcctaatatt ttattatttc attgtccact tgacagggag
      121 ctattcaata tatgttcaag attatttttt atgtttattt ttattgacct ttttgaaaaa
      181 gatattacct aacaaagcaa caacaaaacc tataataaaa tataccatag attagctcca
      241 ccagcaggtt gctccatagg caacagtacc acctgcacca cctagaacac caccagctag
      301 ataaccagga actgagccta caactggtaa aactacatta cctccaaacg ctcctccgat
      361 agctcctccg atagctcctt gaacagtcgc tccacctgcg cctccccagc tacatccacc
      421 accttcaaca ctagcaagtg tttcgaggtc aagggtgtta aggttttcaa ttgtttgagt
      481 tgccatggca actaccccct aaaattttta tcgtgtgatc tctcaatcac atctttagta
      541 tagcattcaa gtgtctctat cagagctagc gtcccaaaaa gtggctatat gtcccgaatg
      601 gtaattccta aagaacatcc ttcaatcatt ggaaatcttc ctctaatttt cacatattta
      661 cttaatcact ttcttattat aacactttta tgcaaatatc ttatagattg cttacagaat
      721 aatcaagcaa atgcgtttat tgtttaaaat attttttgac ttgaaggtaa gatagaaaat
      781 cacagaggat taacaaaagc attaatacgg ctagtactat acggtctgtg gtatcactga
      841 atgttagtaa tgtgtaaaac tctacactaa gcactagaaa tgtgatgaca ggaaagacaa
      901 tgaaggactg ccgtattgtt aacagattta ctgaatctgg acgcttctta agcatacggt
      961 agagcagtcc attaacaaaa atgactacga aagctagtgc tccgactgtt agccaagttc
     1021 ctggcgagat cttgcttttg tagagagaaa ggctgatact tataaggaaa actgccaacg
     1081 cagcagtgat ggttctaaaa gatcgcaata cactcgaact aatattcttt aacttcatga
     1141 taaaacacct aaactatgaa taacctcagt cagtcttgca aacctaataa gctattacat
     1201 ttaactctat tcctctctgt attttattat acagctgtaa gatttcaagt aagcccttag
     1261 cgattaaatt ctactggaga tgtaatacag tagtgtcatt agtactgata ctttaaatag
     1321 gcgaatatac atatctttgt tttctctatt acaaagatat gcaatcaaat ataatataat
     1381 ctccgctatc attagcaaga ataattttac ttcgggaaca tcaaaaataa gcatttgcaa
     1441 gcatcttacg ttcaaagtga ccaaaggtta cttttgaaac tgtacccact ttttaaaaag
     1501 taagctataa agaagcaccg ttagccctag caagttaatg gtatggtgaa ctgcatccaa
     1561 gcttctaaat agattagcga ggcccattac gatgagaatg gtagccagta aatacggttt
     1621 tgagttttta aacatacttt tctccttaaa gtgtttttag ctagtctgtg cataatctat
     1681 gaattttatt atagattgga agccgataaa aaagtagtga cataaatgtc actacttgtc
     1741 tgaccttata tccttgataa ccgtacacat aagaaagaga aataaacata acccgataag
     1801 atttaggcat tgaagtccaa aattcagttt ttctccaaag ttatgtaagg caacaaggac
     1861 gaagcccata gacatcatta gagacactag gcgttttttg gtcatgatta caaataactc
     1921 ttctcttata tcgaaatttt caatcataat tcacatgcta ttcacagacc agcaattgac
     1981 aagacatttc agttaggatt tcttcttaac ggaagatttc ttcttaacgg aattggtagc
     2041 cttgtgtttt tcaagaaatg acataattgg cttatctaaa aaactcataa cagccatgga
     2101 aaccatccct aaaatataac ttttcaaatc aaacataatc catcaccacc agcatgttgc
     2161 tccataacca acaccaccta cgatagcacc tccagctgct cctgcgacag caccttgcca
     2221 agtacgtgtt ttgataccta gtcgtaaacc attaccaact cctgtagcta ctccttgttt
     2281 agcaaaacct ccccagctac atacaccacc ttcaacacta gcaagtgttt cgaggtcaag
     2341 ggtgttaaag ttttcaattg tttgagttgc catggcaact acctcctaaa atttttatcg
     2401 tgtgatctct caatcacatc tttagtatag catacaagtg tctctatcag agctagcgtc
     2461 ccaaaaagtg gctatatgtc ccgagtagta aaaaaaagac tgaatatcat ttttgattca
     2521 gtccatgtct tattgaaaaa gctttaacta attctttcta tactgcctat agactccaaa
     2581 taaaaagaaa aagaatccta ttgatgctaa caaaagttga tagatatttc ctgatgacaa
     2641 tagtactttg ctatataaat atatcatcgc aatagtcgaa aaaatgatta ggtatttctt
     2701 catttgtatc acctatctca aatgaagatt atttagctgt atcataacaa aatgctgtgc
     2761 taccgcctgc aaatccagct cctgcacctg cgatgccaaa gaaagctgca ccgacaatcg
     2821 tcattccggt agtaccaata acacattgag caccatagcc ttgaccactt acattagaca
     2881 atgcatttgt atccagtttt ttaaatcttt caagttgttt attattcata aattcctccc
     2941 atacaaatta gaaacagtat aaggctgcac ctactaacac cccaccgaca gctccccacg
     3001 ggccacctac tgcaccaagt cctcctactg ccagcatccc ctcatcacag gacaacccac
     3061 cctcaacact agcaagtgtt tcgaggtcga gggtgttaaa gttttcaatt gtttgagttg
     3121 ccatggcaac tacctcctaa aatttttatc gtgtgatctc tcaatcacat ctttagtata
     3181 gcattcaagt gtctctatca gagctagcgt cccaaaaagt ggctatatgt cccgaatggt
     3241 aattcctaat gtatattatt tctaaaattc agaaaaaaaa aaaaatctca ttttatactc
     3301 ataaaaaatt gaaaaaccgt tttctttatg ttacaatttt tcaataaaca gtattcgtca
     3361 taaaagagag gactagacct tgaagattta cctattagaa gataattcta ttcagatggg
     3421 tcgcttggaa gaggctgtgg cacatgaact taaatccttc ggaaaagatc tatcttgtgt
     3481 ccagtctttt gacaaacctg accagttgtt atcagctatc acttctaata caagcgatca
     3541 gattttcttt cttgatattg aaattaaagg tgaagataag aagggacttg atatcgctaa
     3601 aatcatacgt caaaataacc cttatgctat cattgccttt gtcactacac atatagagtt
     3661 catgcctcaa gcttttggcg ttacagccta taaatacatc aataaaacct tagatgaagc
     3721 tagctttaga aaagaaatag gggaaaccat tgctcaagtc ttccctatta acgcaactac
     3781 cacggatgag ttttttctct acaaaacaga gtctcaatta ataaaccttc ctatggatca
     3841 aattctatac ctatccacat cagatatcaa acaccatgtt cacctccaga ctatccatac
     3901 cctcatggat atccgagcaa atctggcaga ctttaaaaag atacacaaaa agctctaccc
     3961 atgccatcgg tcctatatcg tcaatacaga tatgatcatc tctgtcaaca agaccaatta
     4021 tgaagctacc ttaattaatg gtcaagttct accagtatcc cgtatgaaga taggaaagat
     4081 tgcacagatt gttgaggaaa gaggcagatg atgttaacaa cgttatggct actttttctc
     4141 acccttttaa gtgcaggcct agaaattatt cttttccttt atttaatggg acagaagatt
     4201 cgtctgaggt attttttcct actccttatt tttaatttag cctttaattt tatttataac
     4261 cactcttctt ggtttatcat taaattctgg ggtgaggata tctactatct tctgctctcc
     4321 ttccttttat ccactaagac taaaaaacca ttaaaaataa agattttcaa tggtctcttc
     4381 cctgatatcc tcaacaacct tagtttaaga ctgattactt tttttatctt tccttttttt
     4441 aatattagta tcaccgatta taaaagctct ctattaatat ccatcccttc atctatcgca
     4501 cctctttgtc tatcatttct ctttattaaa ttattcaagg agagttttac catacttcaa
     4561 aagcagaaat caaattctcc gattcaacat attattatag ttgctaactt ttttatgttt
     4621 gggtacaccc tactgttaca gtccctcatg tatcttgaaa acactactca ctcttcaact
     4681 ttggagcttc gaaaactctg tattgttatt tcacttgtcc tcttcttcat tatgattgtc
     4741 tttttagaaa gaaacattcg tgaaatgatt caaggacaat tggacttcca gaaaaatctc
     4801 cagctagaga atctctacac ctacaataaa catattgaat gtctctacaa ttctgttcgt
     4861 agttttagac acgattatag taatctctta gtcacattac gattggggat agataaagac
     4921 gatatggata ttgtcaaaga agtctatgat agtgtgcttc aagaatccga taaacgatta
     4981 aatacaagaa actttgactt agctagactc gttaatattc aggataatac tttgaaaagc
     5041 cttctgtccg caaaagtttt acaagcagaa gaagaaggta ttgaagctca gattagcatc
     5101 ccagaaccca tccacttgat tgggatggag actctggact tcattatcgt cacttctatt
     5161 tttttagata acgctattga aggtgccatt caaactcaaa accctaaaat tactattagc
     5221 ttttgggaag atcattgttc acagctatta tctattagca ataccataag tgaagaaaaa
     5281 acagaaacca aaaccatatt tgaaagaggt gtctccaaca agggacgaga gcgaggcatt
     5341 ggccttgcta atgtcacaga aatcttagat aactatatca atgtaaactt agaaacacag
     5401 agtaacaatt tctcattcac acaacaatta acaataacta aaaaggccta acagcctttt
     5461 ttctatacct aagcttgagg aatgttatag tcttttgttg gaagcgttct ttgccctccg
     5521 aatcctttta ggaaaccatt tatataatcc atccacccac ttccacctac gacttgttca
     5581 agagcgtggt tatcaagtgt ttcaaagtta ttaatcgtat tgttagccat cagtaattct
     5641 cctcctattg gtcttgcaag tttagtaact tgtctttaaa gtaattgaag taggtctttt
     5701 ggtcaataac gcttgtcaca cgaccttcta gaccgtaacg tagattttgg gcttcttttt
     5761 ctgaaatact tgccctagca gttactctaa acacattccc cctttctgtt tccgtggcag
     5821 aattatcaat actctcaagt tttccaataa ttgtggtacc gtgattacca accttatcca
     5881 aggtcagtcg aactgactgg cctttttgca gttttggcac ataatccgaa ttcacataat
     5941 aagtaatggc aacttcctgg gtttgagtca tatcgggata aagctgggcc aactcagttc
     6001 ctgtcgcagc catggttgct tttttatcag cttgactcaa gtgtaagatt ccatcttctg
     6061 gtgactggat gagggtatta gtcagaagga catctgcctg attgatttta ctctcggtat
     6121 cgttaatttg tgtttccact gagctcaatt gctgtcctgc attttgcaag aattgatttt
     6181 ttagagcttc ttttttagtg ctatcactat tgtcataagt tacaactgtg cctgtcccag
     6241 ccttttggat ttctagatta cctatggaag cattcaagct cgaaatattg gtattaactt
     6301 gagataggta ttggtctgtt acactggcat ccggtgtcgt agcatactga ctgttatagg
     6361 catttaaggt tgcctgatga ggattgcctt caggtaaagt cgtttcatga ttggtaatag
     6421 cttgagagag cgcctcatac tctgagacct gagtctgcaa ttgactaatc tggttatcaa
     6481 tagcagaacc ggtattactc gcaattgctg cttggttatt aacctctgta tttgttttag
     6541 ccacacccaa gtcaatatcc tgtgcctgac ttaggtaggt gttaaaagta ctctgataac
     6601 caaactcgtc ttcctgttct tggaaaagat tggttccctg cgttaggcta gattgcaagg
     6661 tcttcaaacc tgattcctgt ctttttaaaa gttctagttg cttttgaagc ccctcttttt
     6721 gcgatgcctc catggtctct gaatactgaa ctaaggtgtc ccctttttta acaaccttat
     6781 tagcaaccag ttgattatct atgatggtat tgtcactggt tgattggatt actgcgataa
     6841 ccttggttgg ctctatactt cctctagacg tgactgtaac ttccttctta gcaaaaaaag
     6901 cgaaaagaaa aaggaaaata actaacaaaa tcaagggagt aatcaaaaca gtagacatat
     6961 tgtggtagcg acgatggtaa aactctgtgc ttttaaacaa ctgtggattc atcgtgtttc
     7021 cttttcctca ctttctaaat aattgataat agaaacctgg ataagacatt aggtcttgat
     7081 gagaacctgt ctccactacg cgtccgtgat caatgactac gatacggtcg gtccgctcag
     7141 cgatactaag cctgtgtgct acaaagatga tcgttttatc ttttagtgct aggaggttat
     7201 caataacctg cttttctgtc aaaacatcca atccgctagt tgcttcatct aagattagta
     7261 caggagattt cgttagtagt gcacgcgcca aagcgatacg ttgcttttgc cctccagaca
     7321 gacctgctcc atcagacagc tctgtctgaa accccatagg catgttttca atatcttgac
     7381 gaatttctgc tatttcacaa gctttcaaaa tatcagcttg cgtaataccc cgtgctgcac
     7441 ctaaagtaag attttctaaa acactaccac taaatatata ggattgctga gggagatagt
     7501 taatatgttg acgaagagtt ttcttgtcta tgcgactaat attttgacca ttaaaatcta
     7561 tgtgcccctt atatggttga taaaaattga ccaacatttt agctagagta gtcttaccag
     7621 atccactgac accaacaaaa ctgatttttt ctccttgtct aatcgtcaaa ctgacatcag
     7681 tcaaagtatc acgaccaaaa ccatatttat aagataaatc cgtaacagtg atatctccat
     7741 ccgcaatgcc ttcttgatag gtatcatcac tttgtccaaa ctctgattca atcagataga
     7801 cctcattgag cctagtatta gctaccttag cagactgtaa cttggtttgc aggttaatga
     7861 tattttccaa aggattcgtg aagtaagaaa gcaacatatt aaaagtaatc aattgtccta
     7921 tcgaaatggt atttcccatc accaactgag cacctgtcca gaggataagt acatttaaaa
     7981 taagttgagc accttgtttc aatgatgttt gtagtataga taacttagaa aggcgaaaag
     8041 aattgtctag atagtcaata aactcaccat caatcttttg atagcatact tcttcgctgg
     8101 ttagtgactt tatggtttca atcccattaa tgtcctcaat gatggctgaa ttaaccatag
     8161 cattactctg catgacgtca tgattcattc gctcaaaagg tttcataaag gcaaagacga
     8221 taagggtata aattggaacc gaacaaagaa ctagcttgaa gagattgcta ttttgtatca
     8281 ataacacgcc tcctacgata atcacaatag agaaatcaag gaaaagtgat aatatcgtcg
     8341 aagccagagc atcgataata gagttagcat cactaaaacg tgagataacc tcccctgtac
     8401 gtcttgtggc aaaaaaagac attgggagtt caaagatatg tcgtatgtag gacaagataa
     8461 cgtcaatggt aaatcgctga ctcagtatgg ttaagagata atctcttgca aaagtcatca
     8521 tttgttgtaa aacataggtc acaactaatc caattgagat aattcctaag gtagacttca
     8581 tttgattagg gacatattcg tctagaatac cttgtaaata ataggaacct aaaatattta
     8641 ttaaagtaac caagagactg gcaaagacaa tattagctat caaggacctt tgtttaaaga
     8701 tcaaagggag aaagtcccag agtccatttt tcttatcctt atgtggttta taactgggtt
     8761 ccggtcccat aaaaagagta acacctgtcc actctttctc aaaacgctct ttagtcattt
     8821 tagttacttt tacacttgga tcagggtctc caattatcag ataatccttg gtgcttttat
     8881 aaataacata ataatgttga agcttcccat ctttattaac atgagcaata aaaggataag
     8941 gaacatcttc catctcaaag agcgacattt cagcctttat agctctcgtt tcaaagccaa
     9001 tttttttagc agcctctaca agacctaagg cagttgtccc ttctttattg gtcttcgcca
     9061 actcacgcag atgtgctaat gaataatctg aaccatagta cttggccact gatgccaagg
     9121 cagcaactcc acaatccctc atatctattt gagggacaaa agtcctacga aaacgaaaca
     9181 taccaaaccc tttcatcaca aattatcata tgattagtat gtcatatttt caggataaaa
     9241 agagccagcg tcccaaaaag ttgccatacg tcccaaacgg taagaaaaat cttaaagtca
     9301 tctccactat taccatttaa gccgtatttg gggtcattta ggacaagttc attgaaatcg
     9361 atttcaaagt tatacaatag ttattagaag gaaacattct aaaatagtcc tacaagcata
     9421 cgtatttgat ctaaccatta ttactgtgcc agccctggta tttccaaagg aaaccatgac
     9481 tgctgatagc ctcggagcct atctctatcg tatgatgtca taatttgatt atttttattc
     9541 cgaaaaggga taacattatg aaaaacgtca atccatatct caaaaaatcc tatcaaaaaa
     9601 ggctaaatca gcctcttgag attcgattac tcaattatcg gtttaatttt ccttagcttt
     9661 gtaagtgtat ttgttatcac tgtcaatgct atttttagcg tcactagagg ggttcccttc
     9721 cttaatgccc accttatttc caccttgagt aattgtgcct tctatctttt gatttactca
     9781 accttgaggt ggcaccatct caaaaagctc tataatctct acagtggttt ttcccactac
     9841 agaaattata gagccgaagt taagtagttc tgtggtaaac tgagtcatag gaataaatct
     9901 ctttctagta atgttttgca actctactat aacggattta ttcctttttg tgtttacaca
     9961 acttatttta cactacctca acgtttgcaa gtacctcgag atcgagtgtt tcaaatgtat
    10021 tatttgtttg ccttgtcatt ctaacaacct cctaaattat ttttagcttt ttctctcaag
    10081 ctatgatttt attatagggt ggtagccaac aaaaaagtag tgacataaat gtcactactc
    10141 gattttgatt tttaagaaat cttttcgaat atagaagcta tggtctagat tagcttactc
    10201 tccttccatg gcgcctgctt gtaggctgta catcttgtga taggtgccgc cgagggctag
    10261 gagctcttcg tggctaccat gttcaatgat gcggcccttg tctaagacat agatgcagtt
    10321 agcatcttgg attgttgata ggcggtgggc aatggcaatg gttgtacggc cttgacgcat
    10381 ttttgcaaga gagttttgaa caatagcctc tgtctccgaa tcaatattgg ctgtcgcttc
    10441 atccaaaatc aagattttag gctggctagc aacggttcta gcaaaggcta gaagctggcg
    10501 ttgaccggtt gagaaacttg aaccacgttc ggaaactggg gaatcatagc cttctggaag
    10561 tttatcaata aagtgattgg catcgacaaa ctcagcagca gctttaatct cttcatcagt
    10621 taaatcttga tacatggcaa tattggattt gattgtgcca tgatagagga aggggtcctg
    10681 aaggacaaga ccaatattct tgcacagctc tgcctgacta taatcacgaa tatccacacc
    10741 gtctatgaga actcgtcctg attggaattc atagaatcgc atgagcacgt tgataataga
    10801 ggattttcca gagcctgtag atcccacaaa ggcgatggtt tcacctttat tgacagagaa
    10861 ggaaatatta tccaaaatct ggtgcttgcc atcataggag aaggagacat tctcaaagcg
    10921 aatattcccc tcagtaacct tggcagctgt gtctctctgt tcaggctcat aggtacgctc
    10981 gtcaatcaag gcaaagaccc gacctgctga gaccatagag gtttgtagag tcgagaagtt
    11041 ttgtgtcact tcaatcaagg gatcaaagag gcgattaata tactggataa aggcatacat
    11101 ggtacctgct gtgataccca gatagatacc tcggtagcca aaataggcca tgagaacagc
    11161 ataagccagg agcttcagta gactcatggc tgggcgtaga aagagagaat ccagtgatat
    11221 agaacggctg gcataaatca ggtgttcctc attaatggca tcaaactctt ttttaagacg
    11281 cttctcctgg ttaaaggcct gaatgatgtg aatcccttcg atactctctg acagtttggc
    11341 atttatatct gaaagcaagg ctctggtctt ttcaatgatg gccactgatt ttttgcgata
    11401 aaggttaacc aaaaggacaa tcagaggaag aaagaggaca ataagcccgg tcagacgaat
    11461 gtccaagatc atcatggtgt aaagggtggt aacaaagata aagatagccg aaataaaact
    11521 agacagagtt cctgagaaca tctcgctaat ggtctcagta tcattggtca agcgggaaac
    11581 gatggaacct gctggggtct tgtcaaagta agacataccc agtttttcca tattggcaaa
    11641 ggcatctcga cgaatatctc tgacaatgct ataggacaca cgcgcaaaga agagatttcc
    11701 cagatactgg actagtgtct gcaagaggta gagaccatag tagccaatca gaatcatact
    11761 tgccgcctga ttcatatcat gaagatagtg atcaataaaa taagaggcca ccaagggaat
    11821 gatactcttg ataaccgttg tggacaagag gaaggtcaaa gctagaaagg tcaagaactt
    11881 gtaaggcttg agataggtca agagacgctt aaacacagac cattggtttt gattaggcat
    11941 gagcttctcc tccttccatt tctaactgtt gagactcata ggtcttggca taccaaccac
    12001 cttgagctag taagtcgtca tgacgcccac gttcaatgat acgaccatct tgcatgacca
    12061 ggatgaggtc agcgtgcacc accgcactga gacggtgggc ggtaataata gttgttttgt
    12121 ccttgcgagt atgcttaaga ttatcaataa tggcatgttc tgtcttagca tcaaccgcag
    12181 ataaggagtc atccaaaatc aaaatttctg gattcaaaat catggcccgg ctcatagcca
    12241 gacgttgttt ttgaccacct gataggctga cacccttttc accaatgatt gtttcaaagc
    12301 cttcaggcat atccttgata tcatcataaa cttgagctaa cttagtcgct tcttccacct
    12361 tatcaatgga gaaatctgga ttaccaaagc ggatattgtc taaaatagaa ctggcaaaga
    12421 gaaactggtc ttgaggaaca taaccaatca agctacgcaa gtctgatagg cgatagtctc
    12481 ggatgtcatg tccattcaaa tagatggctc cttgattgac atcgtgctcc cgcaagagca
    12541 acttgacaag agccgtcttt cctgagccag tcggtccaac caaaccaagg gtttgcccct
    12601 tgtccaaggt gaaatgaata tctcgcaaag tatcctcatc ctcaaaagca aagcggtcaa
    12661 tcgcaaagtc taaacgacca ttttcaatgc ttggaagagg ataagcggga tcttgaacat
    12721 ctgattcctg ctctaaaaga gtctcgatac gttggtagga cacatttccc ctctgcgtga
    12781 tattaaagag gaagccaatg gccattaggg gccaaaccag catgtccaaa taggtaataa
    12841 aggttaccaa atttccgacc gttatctgac cggcctgaat cataaaggcc ccgacaagga
    12901 gggtcaaaac ataagatgag ccaacaaaga gcaagaccaa aggatcaaaa aggctgtcat
    12961 acttcatggt atgcatattc ttttcaaaag tcatcttatt ggtctcttgg aaggactgga
    13021 gctcagcctc ctgatagcca aaagacttgg ttaccttgat acctgacacc gattcttgta
    13081 ccttattatt aagttcagaa aaagctgcct gggattctcc aaaagctttg tgggtcttac
    13141 gtcccaaacg actagtcgca aaagccatga aaggtagagg taagactgcc atcagggtca
    13201 tctgccagga aatgctgaag aacatggtga ttaaagtcac caaggctgtg atagacgcat
    13261 ccacggctga catgacaccc ccaccagcca aacgggttag agagttgata tcattggtgg
    13321 catgggccat gagatcacca gttcggtact tttggtaaaa agaaggcgac atcttggtaa
    13381 aatgctcaaa aagccgcgaa cgcataatct gtcccaagcg ataagacgtt gccaagatat
    13441 acatccgcca aacatagcgc aaatagtaca ttcctaaagc cgccaaaagc aaataaacga
    13501 gattcaaaag caagatctga ttggtcaatt ttcccgatgt gatagcatca atgacccgac
    13561 ccataaccat aggaggaatc agattgagaa ccgaaaccaa actcagtgcc agtatcccga
    13621 caatataacg gcgtttttct aacttgaaaa accaccaaag ttttgcaatg attgattctt
    13681 taaaaaacaa gttattcccc ctatccctac aaaaggatga ttataagtct aatgaaagtt
    13741 atttccaata gcgataaatt gtaccatctt ctaactgaaa gtgaccaata taagtcaatt
    13801 ttccaaaatc agtagactct ggcaattgat aagcaaagga gtcaaaatta tagaccttgt
    13861 gcccatcatc aatagaatca gttatcctta tcgtggataa ctgattcgtc cttcttaggg
    13921 ttccaaatac gtctgatttc atcagatgtc ttatactctc tgacaaaatt gtacaattcg
    13981 aagttagttg tctcactgag atagcgacca tcagtgttgt agttagctaa ttgagactct
    14041 cttttaacct cagaatagct ccaaacctga cctctttctc gcataatatc ggcatcacgg
    14101 ccacttttga taagtatctg ctttaaccgc tgtcattgtt gctcctagtg tcaatacagt
    14161 gactactgtc acattaagtg t
//
