LOCUS       c00008_JAHBRL0..       23230 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAHBRL010000016.1 Streptococcus thermophilus strain Rico65
            Contig_16, whole genome shotgun sequence.
ACCESSION   JAHBRL010000016
VERSION     JAHBRL010000016
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 01:24:52
            Original ID  :: JAHBRL010000016.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 26671
            Orig. end    :: 49901
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23230
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[36671:39901]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13230
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..23230
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..23230
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             706..1365
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 178.6; E-value: 2.2e-54)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg8_31"
                     /transl_table=11
                     /translation="MARILVIDDQKDIVQLVVKALELQNHNVTGLTSVLDLDKNSLPRF
                     DLILLDIMMPDVEGLQFCHEIRNQVDCPILFITAKTQEADIVQGLSYGADDYICKPFGV
                     KELQARVAAHLRREHRERHHKLSLGEFQFDLSAQELYIENQLLDLTKSEYGICQFLAEN
                     KGQVFSKEQIYTHLYGYEDKGSPAAVAEHIKNIRAKLKEVGQNPIETVWGIGYKWH"
     CDS             1356..2750
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 125.7; E-value: 4.8e-38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg8_32"
                     /transl_table=11
                     /translation="VALIKKREHSLRTILLSYVVSLTVLSVISSLLILYLFSLSFRFGV
                     LIPANQVESDLSAVRSDIETSKVFNPEILPDGTSYVFLTRDFKLKKSNMPVNLQEESLL
                     NYQFKNAHGEKYGYFQSFERSDGIVIVNYQLSPRYRNEWMNQHFPNADLMMIGSMFVSI
                     LIIFIILTFYYANKLSQQLKPILRVTEKISQQDLDFQTSQSTIKEFNQVLSGLDHMRIA
                     LRESLMENWKAEQDKQNQISALTHDLKTPLTVARGNAELLAMTSLDENQTDLLEHFQKG
                     IAQVDTYVKELSEINKMSLKKTLTLEEVPAKEFVEDIYDQTLSLAQTKQINVVFDKKEI
                     AKESIGNWDKSLLNRAIMNIVSNAVEHTPSGSQLLLTARVEEDEFKFICLDSGPGFSLE
                     SLENATQLFYQEDKSRHSRNHSGLGLTIANDIIRLHYGSLSLANDNGTGGAKVTIILPL
                     LNTDDS"
     CDS             2851..4194
                     /locus_tag="ctg8_33"
                     /transl_table=11
                     /translation="MSQSKADYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQ
                     HKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEAHRVPAGGAMAVDREG
                     YAEAVTAEIESHPLIEVIRKEITEIPDDAITVIASGPLTSDALAEKIHELNGGDGFYFY
                     DAAAPIVDKATIDMNKVYLKSRYDKGEAAYLNCPMTKEEFMAFYEALTTAEEAPLNSFE
                     KEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPEDYMGPRDGDFKTPYAVVQLRQDN
                     AAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLKQTFQS
                     KSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKGEDEVIFPHTTAIGSLPYYVTH
                     AESKHFQPMNVNFGIIKELEGPRIRDKKERYEKIAERSLKDLQTFIDA"
     CDS             complement(4459..5256)
                     /locus_tag="ctg8_34"
                     /transl_table=11
                     /translation="VNVADQKANGIDILTDGEFGRSMWHLDFVWGLKGIERYIAEHGYT
                     FKDHDGGQYETRKDIGIRVTEPLSGKNHHYLDIYKLVKAEAGDEDTKQTIWGPAHTYTE
                     LAIFDQLAVPGQVYETNEELKKGLINVYKEFLDEYKAVGGKIVQFDDCLWELFDPSNPA
                     SFYSDGNGDLAELADEFVAINNEVVDYTHELGLTVWTHNCRGNYEIRSAAEGTYEDIAK
                     KFLAEQHYDRFFLEWDSDTAGDIKALEALKDSKAEVVFGLLSS"
     CDS             complement(5253..5408)
                     /locus_tag="ctg8_35"
                     /transl_table=11
                     /translation="MTKSKFQLVGSLLRPADLRKYKDEIEHRDDIQYPFYDALPGYQET
                     ETASIK"
     CDS             5561..5989
                     /locus_tag="ctg8_36"
                     /transl_table=11
                     /translation="MKVGNMQKTFFIIKPDAVKRHLIGQVLDRIERRGFVIERMEMLML
                     DEERLKEHYAQLADKPFFPSISEFMMSGPAVIGIMSGPGVIKSWRDMMGATNPGDAAPG
                     TIRGDFATAPDGDMIPNIVHGSDSEESAAREIKIWFGE"
     CDS             5991..6284
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163:rhodanese domain-containing protein (Score: 59.2;
                     E-value: 5.6e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_37"
                     /transl_table=11
                     /translation="MDIAQIQSELAQDGLLIDVRTPEEYAEGHVKDALLIPHTQFFTAD
                     IPAKKDDSIYLYCKMGSRAEFAAGVLKERGYTKVTTLGGLGDMEALGFKFEK"
     CDS             6495..6836
                     /NRPS_PKS="Domain: PKS_KR (3-112). E-value: 5.2e-11. Score:
                     34.5. Matches aSDomain: nrpspksdomains_ctg8_38_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     110.3; E-value: 1.8e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_38"
                     /transl_table=11
                     /translation="MSKVAIVTGAGQGIGFAISKRLVEDGFKVGVLDYDAETAEKAVVE
                     LSEDKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVHQQNPLDTITEEQFQRT
                     FNINVGGVI"
     aSDomain        6504..6830
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg8_38_PKS_KR.1"
                     /evalue="5.20E-11"
                     /label="ctg8_38_PKS_KR.1"
                     /locus_tag="ctg8_38"
                     /protein_end="112"
                     /protein_start="3"
                     /score="34.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAIVTGAGQGIGFAISKRLVEDGFKVGVLDYDAETAEKAVVELSE
                     DKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVHQQNPLDTITEEQFQRTFNI
                     NVGGV"
     aSModule        6504..6830
                     /domains="nrpspksdomains_ctg8_38_PKS_KR.1"
                     /incomplete
                     /locus_tags="ctg8_38"
                     /tool="antismash"
                     /type="pks"
     CDS             7112..7258
                     /locus_tag="ctg8_39"
                     /transl_table=11
                     /translation="MQTFAKDITLKRLSEPEDVAAAVSFLAGPDSNYITGQTIIVDGGM
                     QFH"
     CDS             7277..7432
                     /locus_tag="ctg8_40"
                     /transl_table=11
                     /translation="MALFFCLIKHNVSDNIVINNYVFKGGFPYQTSYTILLSTHFLVLF
                     YWELLY"
     CDS             7646..9478
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190:GTP-binding protein LepA (Score: 549.8; E-value:
                     1.4e-166)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_41"
                     /transl_table=11
                     /translation="MPNIEELKQRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKDGETYIFHLIDTPGHVDFTYEVSRSLAA
                     CEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRTEIEDVIGL
                     DASEAVLASAKAGIGIEEILEQIVEKVPAPQGDVEAPLQALIFDSVYDAYRGVILQVRV
                     VNGMVKTGDKIQMMSNGKTFDVTEVGIFTPKAVGRDYLATGDVGYVAASIKTVADTRVG
                     DTVTLADNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPET
                     SQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSE
                     FPDPTRIDTIEEPYIKAQIMVPQEYVGAVMELAQRKRGDFETMEYIDDNRVNVIYQIPL
                     AEIVFDFFDKLKSSTRGYASFDYELSEYRRSQLVKMDILLNGDKVDALSFIVHREFAYE
                     RGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARTDIKALRKNVLAKCYGGDVSRKRKLL
                     EKQKAGKKRMKAIGSVEVPQEAFLSVLSMDEDEK"
     CDS             10001..10858
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_42"
                     /sec_met_domain="TIGR01716 (E-value: 4.5e-45, bitscore:
                     145.8, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYGKLFKKFRESRGLVLKDIAKLGVSVSHISRFERENTDLTIS
                     KFMSALNAINMPIDEFMYAANDFQRDEFNEILEKISLFVSARNVSGMEKLLISQVEKIE
                     KRETFYTLNTILIKIRLQDLSDKSYYDESDIQYLSDYLFSVEYWGCYELLLFANTVDVL
                     NHQTMMLLSREMCKRSEFYKDLPNYRRLHSTMLLNCYIISIERDEYIDSLYFEKQLNHS
                     CFTETEIYEKLVFHYSKNLYELKKNRSNKAILEMKKCIAAIKLANSENLAIKFENHLSG
                     VLKM"
     CDS             10918..11718
                     /locus_tag="ctg8_43"
                     /transl_table=11
                     /translation="MRIIKFPEQISEDIIHYTFLDDIISYNCEKCRGSCCHVNNSLLLD
                     AKTASFLKRTYLKDFIVSDDSVSLLSCGKKCWFHSELGCTINDLGLNKPLTCELYPFHI
                     KKIQNFYIVSFTPCPTFQLNLGEGQRYKDIEDVVLRYIKTGVPVFSPSLHVSEERLKYE
                     IEYQNNFKNTLSEYYRTKTADGTTEFKEYEKWYIYYLDFRWGSIPLSYTSSQANQFWNL
                     YKRVCEDVYKKISYIRTDNIYFIIANQFNKTISKHFQLNFIDKE"
     CDS             11778..11930
                     /locus_tag="ctg8_44"
                     /transl_table=11
                     /translation="MQVSDAIAQIELAEEEEVVSSGLSIDIMEIKPSVATELIDGLKGR
                     CPPSV"
     CDS             12013..13230
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Streptide_RRE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_45"
                     /sec_met_domain="PF04055 (E-value: 8e-22, bitscore: 70.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.6e-10, bitscore: 32.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 8.4e-12, bitscore:
                     37.3, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.2e-09, bitscore: 29.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="Streptide_RRE (E-value: 1.8e-16, bitscore:
                     52.4, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSNVYSIFFNWYNKQGILRNNRNNKLFSLNLATFLALKFMYQFS
                     LKKFSDSKSQVIKNVIDFLNNNEISLSKTNTKIVEFSTKIPLKVIQIEVTNKCNLRCMH
                     CYLPDYSKELDRKKISSIVYEAKQLGVMDVDFTGGEPLLLQGLSEIIEEVLKEGMCTTI
                     FTNAVYIPEDFKILIQRYDGIRLKVSLDGWNETIHDSIRGRGTFKRTIKNIEYFRSLGV
                     PVTVNVVLNNKNISGVKYFLELFDRLDVKYAFDRFLPFERNNRLSISDEEFNNAILCIP
                     NIQANCNNISESTFESFYCGAGNSYVFINSSGDVGFCPTLSSTKFCGGNINEKTLNDIW
                     INSKFFNHIRNVRCKYYNECPANYVCQGGCRSRAQFFGGSIGSPDIQECKLAYNLTGIK
                     PKSMSL"
     CDS             13227..13970
                     /locus_tag="ctg8_46"
                     /transl_table=11
                     /translation="MKILSIIYDGGSRIPGARFAPTKYYQEAMLYDRKDSDIITINLGN
                     QDLFSIDLESLSRTIAESKVQIALGGDHSVTYLLAKATVREEAYLIVLDAHLDYFKDFE
                     SVVKNWNFLSFLTDIFEKIIIIGERNFEFPSSFDNKIIILSMEEYWLNKSRVLKKLDSY
                     IDESKDIYLSIDIDVLDPSVFDSVSYPIIGGFQMNDFLGIISKILCSDKVYFCDIVEYN
                     PMVGSDNAHIFYQMIQFVKSKLRRI"
     CDS             13977..15149
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 61.4; E-value: 1.2e-18)"
                     /gene_kind="transport"
                     /locus_tag="ctg8_47"
                     /transl_table=11
                     /translation="LKIKKYAALSIYFNRFSSLISEYGYTILINILLSRISVQLVMYFW
                     VVKCLAAIVTNRINISNSKLSRKYLLILLEITKAILLFLLGFGLNHIIVLLVVFIIEVV
                     NVLFSSLLYSCVPIIIDKDSLIKFNARYTSIGSVSYFLAPLFVGLFINKSHFLLFAVYA
                     LLLIVGATSLLFLPNISTLNLKEERKKQNLNITLFNILRSKKIALVLLSGVIVGSIGVV
                     YDTYEVVYLTKYLGISDSMYSFSLSFLAVSFLVMSFLLSFVKQISSHMKAFALGLSFYV
                     LYLLLFSTSSNIYTVLMSYVFLAIGQTMMGIIETNYFQLSLNMKELQKLYIYSETLHSV
                     FSGIAVLVIGSFAFLSSHLVLVFRSLAVFALFILLCYCVFVNLKKLSIDK"
     CDS             15403..17079
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 502.8;
                     E-value: 2.1e-152)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_48"
                     /transl_table=11
                     /translation="MSEEKQLYGADLVVDSLINHDVEYVFGIPGAKIDRVFDTLEDKGP
                     ELIVARHEQNAAFMAQGVGRITGKPGVVLVTSGPGVSNLATGLVTATDEGDPVLAIGGQ
                     VKRADLLKRAHQSMNNVAMLEPITKYAAEVHDANTLSETVANAYRHAKSGKPGASFISI
                     PQDVTDAPVSVKAIKPMTDPKLGSASVSDINYLAQAIKNAVLPVFLLGNGASSEAVTYS
                     IRQILKHVKLPVVETFQGAGIVSRDLEEDTFFGRVGLFRNQPGDMLLKKSDLVIAIGYD
                     PIEYEARNWNAEISARIIVIDVEPAEVDTYFQPERELIGNVEASLNLLLPAIQGYKLPE
                     GSVEYLKGLKNNVVEDVKFDRQPDEGTVHPLDLIEVLQEQTDDDMTVTVDVGSHYIWMA
                     RYFKSYEPRHLLFSNGMQTLGVALPWAISAALVRPKTKVISVSGDGGFLFSAQELETAV
                     RLKLPIVHIIWNDGHYNMVEFQEEMKYGRSSGVDFGPVDFVKYAESFGAKGYRATSKAA
                     FASLLQEALTQAVDGPVLIDVPIDYRDNIKLGETILPDEFY"
     CDS             17095..17814
                     /locus_tag="ctg8_49"
                     /transl_table=11
                     /translation="MSEAIKLFQYNTLGALMAGLYGGTLTVGELLEHGDLGLGTLDSID
                     GELIVLDGKAYQAKGSEGKVEVVEVSPDEKVPYAAVVPHQAEVIFRQRYEMTDKELEDR
                     IESYYDGVNLFRSIKIKGHFKHMHVRMIPKSNADIKFADVATRQPEYEVDDISGTIVGI
                     WTPEMFHGVSVAGYHLHFISDDLTFGGHVMDFVIENGIIEVGPVDQLDQRFPVQDRQYL
                     FAKFNVDEMRKDITKAE"
     CDS             complement(17751..18974)
                     /gene_functions="other (smcogs) SMCOG1206:transposase
                     (Score: 372.3; E-value: 4.8e-113)"
                     /gene_kind="other"
                     /locus_tag="ctg8_50"
                     /transl_table=11
                     /translation="MIKYDFQKPSKIPLLEQAGTPTLLRLKKRRFQCKSCRRVTVAETS
                     IVEKNCQISNLVRQKVTQLLTEKVSLTDIARRLRVSTSTVYRKLDQFTFKEHYDKLPAV
                     MSWDEFGFKKGELAFVAQNYETNELITILDNRRQTTIRNYFLKYPLKVRQQVQFITMDM
                     SGAYIPLARKLFPNAKIVLDRFHIIQHLGRAFLKTRIAIMNQFDKKSLPYRALKNHWRL
                     FQKDSRKLSLNSFYSKTFRQTLAPHEVVAKTLVFSKELTDYYTLYQLLLFHFQEKRVDE
                     FFELIEENRSKVNHYFQTVFRTFLRHKQYIKNALETDYSNAKLKATNKLIKDIKRLGFG
                     FRNFINFKKRVFITLNIHKKGPIRSSLDVSFSLPTTVDKETVSYLYAYSALVISLRISS
                     TLNLAKRY"
     CDS             complement(19329..21047)
                     /locus_tag="ctg8_51"
                     /transl_table=11
                     /translation="MSYTENYQKWLDFAELPAYLRDELVSMDEKTKEDAFYTNLEFGTA
                     GMRGLIGAGTNRINIYVVRQATEGLAQLIDSKGEEAKKRGVAIAYDSRHFSPEFAFESA
                     QVLAAHGIKSYVFESLRPTPELSFAVRHLHTFAGIMITASHNPAPFNGYKVYGEDGGQM
                     PPADADALTDYIRAIDNPFTVKLADLEDSKASGLIEIIGENVDAEYLKEVKDVNINQDL
                     INEYGRDMKIVYTSLHGTGEMLARRALAQAGFDAVQVVEAQAVPHADFLTVKSPNPENQ
                     DAFALAEELGRNVDADVLVATDPDADRLGVEIRQPDGSYLNLSGNQIGAIIAKYILEAH
                     KTAGTLPANAALCKSIVSTELVTKIAESYGATMFNVLTGFKFIGEKIHEFETQHNYTYM
                     FGFEESFGYLIKPFVRDKDAIQAVLIVAEIAAYYRSRGMTLADGIEEIYKQYGYFSEKT
                     ISVTLSGVDGAAEIKKIMDKFRRNAPKQFNNTDIAKTEDFLEQTATTADGVEKLTTPPS
                     NVLKYILADDSWFAVRPSGTEPKIKFYIATVGETEADAKEKIANIEAEINAFVGE"
     CDS             complement(21130..21705)
                     /locus_tag="ctg8_52"
                     /transl_table=11
                     /translation="MMNKKNKANPTAQLALLIATMVVIEVLSQTIFAAFALPIKLTLTH
                     IPVIIASIVYGPKIGAYLGGFMGIMSIVRNTIVYTVGSYLFSPFVEGGTWASAVIAIVP
                     RILIGIFPYFIYKLLQNRLGLMLSGVLGAFTNTFFVLLGIYFLIPNFYSAGGKTLMATI
                     FTINSVAEMVIAGLLTLSITPMLLRLKK"
     CDS             complement(21730..22290)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_53"
                     /sec_met_domain="Flavoprotein (E-value: 4.8e-42, bitscore:
                     134.9, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYAMTKRIILAVSGSISAYKSADLTSKLKKKGYDIHVIMTESA
                     QSFITPLTLQALSKNPVHSDVMEEKLAERINHIDLAKKTDLFIVAPASANTIAKLAHGM
                     ADNMLTATALALPSTTPKLIAPAMNTKMYENPLTKKNLKILQEVGYQEILPKSGLLACG
                     DTGRGALADISVIIESIDNALTK"
     CDS             complement(22268..22951)
                     /locus_tag="ctg8_54"
                     /transl_table=11
                     /translation="MKILITSGGTTEKIDDVRGITNHSTGYLGKEIAELFLAKGHQVTL
                     VTVKTAVKPEPKENLKITEITNVDSLLKSMEPLVKEHDVLIHSMAISDYTPIYMTDFTE
                     LEDTENPSQLLHKSNTESKISSASDYQVLFLKKTPKIISLVKQWNPNIQLVGFKLLANV
                     SKEDLFKAARASLKRNQANIIVANDLGEITPNQHIAYLVDEKGEEMVTTKSAIAQALYE
                     RICYD"
ORIGIN
        1 tgtgattgag ggttttattc atacccataa ccggaagaaa tacttcctaa agatttattc
       61 tttagcaatt gtgatgggac tgattcaatt tggattctat aattttctac atcctctagt
      121 tagaccagat ggtttctttc cacaaaatat gatgctgtcg tcattcgcaa ttttgctcgt
      181 tgctcttcaa gggattgcat ggattcaaga aaagaaatac cttaaaggga taccaacttt
      241 actttttcca ttgttgcttc catggttaat gatgcctttt tatctgctaa gtgtgaacaa
      301 acctatgttt ggttttctac taaatttact caatttcaca gtattgccag tccatacatt
      361 tatcagtgat ggaggaacgt ggttgctttt gaccggtatc gctatgtatc tttgtcatag
      421 gaatcttaag aaagaagtgc ttgcttttat gagtgttagt ctcgtttggc tgctaatggc
      481 gattgtttta agtagacctt cttttcacga tttaatattc aaatactttg aatggatgga
      541 aatattttca gcacctttaa tgctttctta taacggtcaa agagggaaag ggtcaaaata
      601 tttgttctat gttttttacc caacccatat ttatctactt tacgccttgt cagttatctt
      661 ctatagatga tatgatatgg ataactttga aggaaaggaa aggctatggc tcgaatactt
      721 gttattgatg atcaaaaaga tattgttcaa ttggttgtaa aggctttaga gctccaaaac
      781 cataatgtga cagggcttac aagtgtttta gatttggata agaactcttt acctcgattt
      841 gacctgattt tactggatat tatgatgcct gatgttgaag gtctacagtt ttgccatgag
      901 attcgaaatc aggtggattg cccaatcctc tttattacag ctaaaacgca agaagcagac
      961 attgtccaag ggttgagtta tggtgcggat gattacattt gcaaaccatt tggagttaaa
     1021 gaactccaag cgcgtgttgc agctcacttg agacgtgaac atcgtgagcg tcaccataag
     1081 ctttcacttg gggagtttca gtttgacttg tctgctcaag agctttatat tgagaatcag
     1141 ttgttagatt tgacaaagtc ggaatatggt atttgccagt ttttagctga aaataagggc
     1201 caagtctttt caaaagaaca aatctacacg catttgtacg gctatgagga taaaggcagt
     1261 ccggcagcag tggctgaaca tatcaagaat atccgtgcaa agcttaaaga agttgggcaa
     1321 aatcctattg aaacagtttg ggggattggt tacaagtggc actaataaaa aaacgagaac
     1381 actctctaag aacaatcttg ttatcttatg tcgtcagtct tacagttctc tctgtaatca
     1441 gcagtcttct tattttgtat ttgttcagct tgtcttttcg ttttggagtt ttgattccag
     1501 caaatcaagt tgagagtgat ttgtctgctg tgagaagtga tattgaaact tctaaggtct
     1561 ttaatcccga gattttacct gatggcacga gttatgtctt tttaactaga gattttaagc
     1621 ttaaaaagtc taacatgcct gttaacttgc aagaagaatc cttactaaat taccaattca
     1681 agaatgctca cggtgagaaa tacggctatt ttcagtcttt tgaacgatca gatggcatag
     1741 tcattgtcaa ttatcaacta tcacctcggt accgtaatga gtggatgaac cagcattttc
     1801 ccaatgctga tcttatgatg attggttcaa tgtttgtatc tatcttaatc atatttatta
     1861 ttttaacttt ttattatgca aataaattga gtcagcaact taaacctata ttaagggtta
     1921 ctgaaaaaat ttcccaacaa gatttggatt ttcaaacttc tcagtctaca attaaggaat
     1981 ttaatcaggt tttaagtggt ttggatcata tgcgtatagc acttcgtgag tctttgatgg
     2041 aaaattggaa ggcagagcaa gataaacaaa atcagatttc tgccctgaca catgacttaa
     2101 agacgcccct aacagttgct cgtggaaatg cggaactctt agctatgacg tccttggatg
     2161 aaaatcaaac ggacttgtta gagcattttc aaaaaggtat tgcacaggtt gatacttatg
     2221 taaaagagtt gtcagaaatc aacaaaatga gtttgaagaa gaccctgacg cttgaagaag
     2281 ttccagctaa ggaatttgtt gaagacattt acgatcaaac cttgtcatta gctcaaacga
     2341 aacaaatcaa tgtggtattt gacaagaagg aaattgcgaa agaaagcata ggcaattggg
     2401 ataagtcctt gttgaatcga gctattatga atattgtttc aaatgccgta gagcatacac
     2461 ccagtggcag tcagttgctc ctgaccgcta gggtagaaga agatgaattc aagtttatat
     2521 gccttgattc tggtcctgga ttttcccttg aatctcttga aaacgctact cagctatttt
     2581 atcaagagga taaaagcaga catagtcgca atcatagtgg ccttggtctg actattgcca
     2641 atgatattat tcgtttacac tatggtagtc tttctcttgc aaatgacaat ggcacgggtg
     2701 gtgctaaagt gactatcatt ttaccccttt taaatacaga tgactcctag tcgccagatg
     2761 aggagttttt tgctatacta ctaagagtaa aaatgaagaa agatttgtgg gagcaggatt
     2821 tcatcttgtt tccgaagagg tattagtgtc atgtctcaat caaaagcaga ttatattaac
     2881 gtgattggag ctggtttggc cggatccgag gcggcttatc agattgccaa acgtggtatt
     2941 ccagtaaaac tttatgaaat gcgtggggtc aaagcaacac cacagcataa gacaacaaat
     3001 tttgcagaat tggtttgctc taactctttc cgtggagata gcttgaccaa tgctgtaggg
     3061 cttctaaaag aagaaatgcg tcgtttggac tctatcatta tgcgtaatgg agaagctcac
     3121 cgtgtgccag caggtggtgc catggcggtg gaccgtgaag gctatgcaga agcagtgaca
     3181 gctgaaattg aaagtcatcc cttaattgaa gttatccgta aagaaatcac agaaattcct
     3241 gatgatgcta ttacagttat tgcttcaggt cccctaactt ctgatgcttt agctgaaaag
     3301 attcatgagc ttaacggtgg agacgggttc tatttctatg atgccgctgc accaatcgtt
     3361 gataaagcaa ctatcgacat gaacaaggtt taccttaagt cacgctatga taagggtgaa
     3421 gcagcttatc taaactgtcc aatgaccaag gaagagttca tggccttcta tgaggccttg
     3481 actacagctg aagaagctcc tttgaattct tttgaaaaag aaaagtattt cgaagggtgt
     3541 atgcctatcg aggttatggc taaacgtggt attaaaacaa tgctctacgg tcctatgaaa
     3601 ccagttggtt tggagtatcc tgaagattat atgggtccac gtgatggtga cttcaagacc
     3661 ccttatgcgg ttgttcagct tcgtcaggac aatgcggctg gtagcctcta caatatcgtt
     3721 ggtttccaaa cccacctcaa atggggagag caaaaacgtg tcttccaaat gattccaggt
     3781 cttgaaaatg cagaatttgt tcgttatggg gtaatgcacc gtaactctta catggattcg
     3841 ccaaacttgc ttaaacagac cttccaatca aaatcaaacc ctaatctgtt ctttgctgga
     3901 caaatgactg gtgttgaagg ttatgttgaa tcagctgcct caggtttggt tgctggaatc
     3961 aatgcagccc gtctttttaa gggtgaagat gaagttattt tccctcatac aacagcaatc
     4021 ggtagccttc catattatgt gacacatgct gaaagcaaac atttccaacc aatgaatgtt
     4081 aactttggta ttatcaaaga attagaaggc ccacgtattc gtgacaagaa agagcgttat
     4141 gaaaaaatcg cagaaagatc tcttaaggat ttgcaaactt ttatagatgc ttgatgctaa
     4201 cataaaaagc cctcacaaga gtgaaggctt ttcgttttag agaggagcga atagaaatat
     4261 cgattagcca aagaatttct tagcgatttc ttgaccttgt ttgattttag cccattgttg
     4321 aggtgttgcc agctcattac ctgagtcaca tgaggcgaaa ccacattggt gagagaggaa
     4381 gagacgtttt tttggaagga tttgactcgc tttttcaagc aaatcgagaa cacgttcttc
     4441 gtcatctagg tcagtcgttt aagaagacaa tagcccaaat acaacttcag ctttactgtc
     4501 tttaagggct tccagagctt tgatatcacc agctgtatcg ctatcccatt caaggaagaa
     4561 gcggtcatag tgttgctctg ccaagaattt cttagcgatg tcttcgtaag ttccttcagc
     4621 agcagaacgg atttcataat taccacgaca gttgtgtgtc caaaccgtta aaccaagttc
     4681 gtgagtatag tcaacaacct cattattgat agcaacaaat tcatcggcca attctgccaa
     4741 atcaccattg ccgtctgagt agaaacttgc agggtttgat gggtcaaaaa gttcccagag
     4801 gcagtcatca aattgaacga ttttaccacc aacagccttg tattcatcta agaattcttt
     4861 atagacatta atcaaacctt ttttgagttc ttcgtttgtt tcatagactt gtccaggaac
     4921 agccaattga tcaaagatag caagttcagt gtaggtatga gcaggtcccc agatagtttg
     4981 tttggtatct tcatcaccag cttcagcctt aaccaatttg taaatatcta ggtagtggtg
     5041 gtttttacct gagagaggct cagtgacacg aataccgata tctttacgtg tttcatattg
     5101 accaccatca tggtctttaa aagtataacc atgctcagca atgtagcgtt caataccttt
     5161 gagtccccag acaaagtcca agtgccacat agaacgtcca aactccccat cggtaaggat
     5221 gtcaattccg ttagcttttt ggtcagccac attcacttaa tagatgcagt ttcagtttct
     5281 tgataaccag gaagggcatc atagaaagga tactggatgt cgtcacgatg ctcgatttcg
     5341 tccttgtatt tacggagatc cgcaggacga agaagagaac cgactaattg gaatttagat
     5401 tttgtcatta aatttacctc gaaatgtcta tttacatcta tattatctct tatgggaact
     5461 aatgaaaaat agttaatttc ttgctgtgga tatagtttta gactatacaa ggtttagctc
     5521 tgcaaaatga tacttcttat gataaaatgg aaagaaaacg atgaaggttg ggaatatgca
     5581 aaaaacattc tttattatta aaccagatgc tgttaaacgc catctaattg gtcaagtgct
     5641 tgatcgaatt gagcgacgtg gcttcgttat tgagcgtatg gagatgctga tgcttgacga
     5701 agaacgtctt aaagaacatt atgcccaatt ggctgataaa ccttttttcc ctagtatttc
     5761 tgaattcatg atgagtggtc cagcagttat tggtattatg tccggcccag gtgttattaa
     5821 gtcatggcgt gatatgatgg gagcaactaa tcctggggat gctgctcctg gaacgattcg
     5881 tggagacttt gcaacagcac cagatggtga catgattcca aatatcgttc atggctctga
     5941 ttcagaagaa tctgcggctc gagaaattaa gatttggttt ggtgagtagg atggatatag
     6001 cacagattca atcagaatta gctcaggatg gactattaat tgatgtcagg actccagaag
     6061 agtacgcaga aggtcatgtt aaggatgctt tattaatacc tcacacgcag tttttcacag
     6121 ctgacattcc agctaaaaaa gacgattcaa tttatcttta ttgtaaaatg ggatctcgtg
     6181 ctgaatttgc tgcaggtgta ctgaaagaac gaggatatac taaggttacc accttaggtg
     6241 gcctaggtga tatggaagca ctagggttta agtttgaaaa ataatacaca taaggtcact
     6301 agtggtgatc ttatttgctt tcaaaaagca tgacaaatta ttaacaacgc ttttataaag
     6361 gggtagaatc ttaattgagt taagacaaag cctatgaaaa tgactttgcc agaacttgat
     6421 taacttagca tattccaatt gagatagggc ttgtggttaa gcttgtgact acaattggta
     6481 gaggaggatt tcgtatgtca aaagttgcta ttgttacagg tgcaggtcaa ggtattggtt
     6541 ttgcgatttc aaaacgcttg gttgaagatg gttttaaagt cggggtattg gactatgacg
     6601 ctgaaactgc tgaaaaagca gttgttgagt tgtcagaaga caaggcattt tccgttgtag
     6661 cagatgtgtc taaacaagct gaggtagcag cagctttcca aaaagtagtt gatcactttg
     6721 gcgacttgaa tgttgttgtt aataatgctg gtgtgcacca acaaaacccc cttgacacta
     6781 ttactgaaga acagtttcaa cgtacattta acattaatgt tggtggagtt atctgaggtg
     6841 cacaagctgc ccaagcacaa tttaaatcac ttggtcatgg tggtaaaatt atcaatgcaa
     6901 ctttacaagc aggtgttgta gggaactcta acttaactgt atatggtgga actaaattcg
     6961 tagttcgtgg tattactcaa actttggcgc gtgacttagc tgattcaggt ataactgtaa
     7021 atgcttatgc accaggtatc gttaagactc caatgatgtt tgacatttcc cacgaagttg
     7081 gtaaaatgct ggtaaagatg atgagtaggg tatgcaaact tttgctaaag atattaccct
     7141 caaacgtttg tcagaacctg aagatgttgc agcagcagtt agcttcctag ctggacctga
     7201 ctcaaactac atcacaggtc aaacaatcat cgttgatggt ggtatgcaat tccattaagg
     7261 ttaaaaggga gagcgaatgg ctctcttttt ttgcttgata aaacataatg tttctgataa
     7321 tatagttata aataattatg tttttaaagg tggattccca tatcagacat cttacactat
     7381 attgctgagc acccattttt tagtcttatt ctattgggaa ttattgtact agcctttggt
     7441 ttagctccat tttcaagtag ttcaatagag aacaagcgtt cagctattat taataagcac
     7501 tacaatgata attttaagaa ataagaagga ctaaatgcag tcataaagca gatattagag
     7561 ataggcaaat gcctgtcttt tttgtataat aggaggtgac ggttcgtttt ttaacaatca
     7621 caagtaagaa ctaggaaaga ataaaatgcc aaatattgaa gaattaaaac aaagacagga
     7681 gaagattcgc aacttctcga ttattgctca tattgaccat ggtaaatcaa cgcttgctga
     7741 ccgtatcttg gaaaagactg agactgtatc aagtcgtgag atgcaggcac aactccttga
     7801 tagtatggat cttgagcgcg aacgtggtat cactatcaaa ctgaatgcca ttgagcttaa
     7861 ctacaaagct aaagacggcg agacttatat tttccacctt atcgacacac cgggacatgt
     7921 ggactttact tatgaggtgt cacgttccct tgccgcctgt gagggtgcta tcttggtggt
     7981 agatgcagct caagggattg aagcacaaac acttgccaat gtttacttgg cacttgataa
     8041 tgacttggaa atcttaccag ttatcaataa aatcgacctt ccagcggcag atcctgagcg
     8101 tgtacgtaca gagattgaag atgttatcgg attagatgcc tcggaagctg tgcttgcatc
     8161 agctaaggct ggcattggta tcgaagagat tctcgaacaa attgttgaga aagttcctgc
     8221 gccccaaggt gatgtggaag cacctctcca agcccttatc tttgactctg tttatgatgc
     8281 gtatcgtggc gtcatactcc aagtgcgtgt ggttaacgga atggttaaaa cgggcgataa
     8341 gattcaaatg atgtctaatg gcaagacctt tgacgttact gaggttggta ttttcactcc
     8401 taaagctgtt ggccgtgact accttgcgac tggagatgtt ggttatgtag cagcttcaat
     8461 taagacagtt gcggatactc gtgtcggtga tacagtgaca cttgcggata atccagccgc
     8521 agaaccactt catggttata agcaaatgaa cccaatggtc tttgctggtc tttatccgat
     8581 tgagtcaaat aaatataacg acttgcgtga ggctcttgaa aagctccaat tgaatgatgc
     8641 cagtcttcaa tttgagcctg aaacgtctca agcccttggt tttggtttcc gttgtggttt
     8701 cttgggcctt cttcacatgg atgttatcca agagcgtttg gaacgtgagt ttaacatcga
     8761 tctcatcatg actgcaccat cagtagttta ccatgttaac actactgacg gtgaaatgct
     8821 tgaagtgtcc aacccatctg aatttccaga tcctacacgt attgatacca ttgaagagcc
     8881 ttatatcaaa gctcaaatta tggttcctca agagtatgtt ggtgctgtta tggagttggc
     8941 gcaacgtaaa cgtggtgatt ttgaaaccat ggaatatatt gatgataatc gtgttaacgt
     9001 tatctatcaa attccacttg ctgaaatcgt ctttgacttc tttgataaat tgaagtcatc
     9061 aactcgtggt tatgcaagtt ttgactatga attgtcagag taccgtcgtt cacaattggt
     9121 gaaaatggat attctcctta atggtgataa ggtcgatgcc cttagcttta ttgtccatag
     9181 agaatttgcc tacgaacgtg gaaaacttat cgttgataaa cttaagaaaa ttattccacg
     9241 tcaacaattt gaagttccta tccaagcggc tattggtcaa aaaattgttg cccgtacaga
     9301 tatcaaagct cttcgtaaaa acgtcttggc taaatgttac ggtggtgacg tttcacgtaa
     9361 acgtaaactc ctcgaaaaac aaaaagccgg taagaaacgt atgaaagcca tcggttcggt
     9421 ggaggtacca caagaagcct tcttgtctgt gctttcaatg gacgaagatg agaaataaga
     9481 atgatagtag aatgtgatgt tctggctatt ttagtaaaaa gttatgataa agaggatttt
     9541 aaaatttacc ttctcaaagt gacgtataga gaatggcacc actaatccaa catataaaac
     9601 attggaagaa attgccgctg caaccaatac tagattagtt gttgactttg ttccaataaa
     9661 gaactagttt ttgtatacac tcaaaaagct ctataatctc tatagtggtt ttacctacta
     9721 cagaaatcat agagtctttt ttatattata cccttattag agaacagcat cataccttaa
     9781 ctacaccaca aaagttagac atcgaaagtc taacttttgt ggtgtcttta ttttctattt
     9841 gtttagccaa cagcaattac aataatgctt tcaaaaatta gaagtaagat agctaaaaaa
     9901 ctttctttat tcatagaaat taacctccta tctcactata tgatataata cttttaagtt
     9961 tatctgggaa attctcgtat atgcaaaaga ggtgcttttt atgaaagatt atggaaaatt
    10021 atttaagaaa tttagagagt ctaggggatt agtcttaaaa gatatcgcaa agttaggcgt
    10081 atcagtatct catatttccc gctttgaacg tgaaaataca gatttgacaa ttagtaagtt
    10141 tatgtcagct ttaaatgcga taaatatgcc tattgatgag tttatgtatg cagcaaacga
    10201 ctttcagaga gatgagttta atgaaatctt agaaaagatt agtttatttg tttcagcaag
    10261 gaacgtgtca ggtatggaaa agttattaat ctctcaagta gaaaaaatcg aaaagcgtga
    10321 gactttttat actctaaata ctattttaat aaaaattcgt ttacaggact tatcagacaa
    10381 aagttactat gatgaatctg atatccaata tttatcagac tacctattct ctgtagaata
    10441 ttggggttgt tacgaactac tgttatttgc gaatactgta gatgtattga atcatcaaac
    10501 aatgatgctt ttatcaagag aaatgtgtaa acgttcagaa ttttacaagg atttaccaaa
    10561 ctaccgaagg ttacactcaa caatgctatt aaattgttat atcataagta ttgaaagaga
    10621 tgagtatatt gattcgttgt attttgaaaa acagttaaat catagttgtt ttacggaaac
    10681 tgagatttac gagaaattag tgtttcatta ttcaaaaaat ttatatgaat taaagaagaa
    10741 taggagcaat aaagctattc tagaaatgaa gaagtgtatt gctgcaatta agctggctaa
    10801 tagtgagaat ttagctataa aatttgaaaa tcatttatct ggagtgttaa aaatgtagtt
    10861 ggatttgtgt atatggtata aattatcagt gtcaaaatta aatgatatat tattgatatg
    10921 agaattatta aatttcctga acagatttca gaagatatca ttcattatac gtttctagat
    10981 gatattatct cttataattg tgaaaagtgt agaggatctt gttgtcatgt gaataattct
    11041 ttattacttg atgcaaagac agcaagtttt ctaaaacgca cgtatcttaa agattttatt
    11101 gttagtgatg atagtgtttc attgttgagt tgtggtaaaa agtgctggtt tcattctgaa
    11161 ttgggttgta cgataaatga tttaggcttg aacaagccat taacttgtga attatatcct
    11221 tttcatatta agaaaattca gaacttctat attgtttctt ttactccttg tccgacattt
    11281 caactgaacc ttggtgaggg gcagaggtac aaggatatag aggatgtagt tttacgatat
    11341 attaaaactg gggtgccagt ttttagtccg tctttgcatg tttcagagga aaggctgaaa
    11401 tatgagattg agtatcaaaa caattttaaa aacactttat cagagtatta tcgaacaaag
    11461 actgccgatg gcactacaga gtttaaagaa tatgaaaaat ggtatatata ttatttagat
    11521 tttagatggg gaagtatacc cttatcttat acaagttcac aagcaaatca attttggaat
    11581 ctttacaaga gagtttgtga agatgtttat aaaaaaatat catatatacg aacagataac
    11641 atatacttta ttattgcaaa tcagtttaat aagacaattt caaagcattt tcagctaaat
    11701 tttatagata aagaatgatt tctatgattt gttatgggta cttattgatt cttaaataaa
    11761 taatggagga tattacgatg caagttagtg atgctattgc acaaattgaa ttagcagaag
    11821 aagaagaagt tgtttctagc ggtctatcta ttgacattat ggaaattaaa ccttctgttg
    11881 ctacagagtt gattgatgga ctcaaaggtc gttgcccacc gtctgtctaa tagaactgat
    11941 tgtaggatta gagtctattt ctaatccttt ggtttttata ttaatatttt tggaagattg
    12001 cagggaatta atatgacgag caatgtttac tcgatttttt ttaattggta caataagcaa
    12061 ggaatactca ggaataatag gaataataaa ctattttcat taaatttagc tacattttta
    12121 gctttaaaat ttatgtacca attttcattg aaaaagtttt ctgattcaaa gagtcaggta
    12181 ataaaaaatg ttatagattt tctaaataac aatgaaatat cactctctaa gaccaacact
    12241 aaaattgttg aattttcaac gaaaatacca ttaaaagtga tacagattga ggtcacgaac
    12301 aaatgtaacc taagatgtat gcattgttat ttacctgatt attcaaagga gctcgataga
    12361 aagaaaattt caagtatagt atatgaagct aagcagctag gagtaatgga tgttgatttc
    12421 actggaggcg aaccattatt attacaggga ttaagtgaaa ttatcgagga agtattaaaa
    12481 gagggaatgt gtacaacaat ttttacaaat gctgtatata ttcctgaaga ttttaaaata
    12541 ttgattcaaa gatatgatgg tataagacta aaagttagtt tagatggttg gaatgaaaca
    12601 atacatgatt caattagagg aagaggtaca tttaagagaa caattaagaa tattgaatat
    12661 tttaggagtt taggagtacc tgttactgtt aatgttgttt tgaataacaa gaatattagt
    12721 ggagtgaagt attttttgga gttgtttgat cgattagatg tgaaatatgc ttttgatagg
    12781 tttttacctt ttgaaaggaa taatcgacta tcaattagtg atgaagaatt caataatgct
    12841 attttgtgta ttcccaatat tcaagcaaat tgtaataata tatccgaatc cacatttgaa
    12901 tcattttatt gtggtgctgg caattcttat gtgtttataa attcgtcagg tgatgttgga
    12961 ttttgtccga cattatcctc cactaaattt tgtggaggta acattaatga aaagacttta
    13021 aatgatattt ggattaattc gaagttcttc aatcatattc gaaatgtacg atgtaagtat
    13081 tataatgaat gccctgcaaa ttatgtttgt caaggtgggt gtagaagtcg agctcagttt
    13141 ttcggaggtt ctattgggag tcccgatata caggagtgca agttagcata taatttaact
    13201 gggattaagc caaagtcaat gagtttatga aaatattatc tattatttat gatggtggaa
    13261 gtagaattcc aggagcgaga tttgctccca caaaatatta tcaagaagcg atgttatatg
    13321 ataggaaaga ttctgatata attacaatta atttaggtaa tcaagattta ttttctattg
    13381 atttagaaag tctaagtcga actattgctg aatctaaagt tcagattgct ttaggaggag
    13441 atcattcagt tacttatcta ttagcaaagg ccactgttcg agaggaagca tatttaattg
    13501 ttttagatgc tcatttagat tacttcaaag actttgaaag tgttgtaaaa aattggaatt
    13561 ttttaagttt tttaaccgat atttttgaaa aaataattat cattggggaa aggaattttg
    13621 agtttcctag ttcatttgat aataaaataa tcatcctctc aatggaggag tattggttaa
    13681 ataagagtag agttttgaaa aagttagata gttatattga tgagtcaaaa gatatttact
    13741 tatcaataga cattgatgtt ttggatccat ctgtttttga ttcagtatca tatcctatta
    13801 ttggaggatt tcaaatgaac gattttcttg gaataatttc caaaatttta tgttctgata
    13861 aggtatattt ttgtgatata gttgagtaca atccgatggt tggaagtgat aatgctcaca
    13921 ttttttacca aatgattcaa tttgttaaat caaaattaag gaggatatag gaaatattga
    13981 aaataaaaaa atatgcagca ttgagtattt attttaatcg tttctcatcg ttaatctcag
    14041 agtatggtta tactatcttg atcaacattc tattgtctag aatttctgtg caattagtta
    14101 tgtatttttg ggtggtaaag tgtttagctg caatagttac aaataggatt aatatctcaa
    14161 atagtaaact gagcagaaaa tacctgctta ttctgttaga aattacaaag gcaatcttac
    14221 ttttcttact aggttttgga ttaaaccata taattgtcct attagttgta ttcataattg
    14281 aggttgtcaa tgtattgttt tccagtttat tatatagttg tgtaccaatt attatagaca
    14341 aggattcatt gattaagttt aacgctaggt atacaagcat tggttcagta tcttattttt
    14401 tagcaccgtt gtttgttggt ttatttatta ataaaagtca ctttttattg tttgcagttt
    14461 atgctcttct tttgatagtg ggagctacta gtcttttatt tttaccaaat atttcgactt
    14521 taaatttgaa agaagaaaga aaaaaacaaa atttaaacat tacattattt aacattctga
    14581 gatccaaaaa aattgcatta gttctattat ctggagttat tgtgggatca attggagttg
    14641 tttatgatac ttatgaagtt gtttatttaa caaagtatct cggtattagt gattctatgt
    14701 attccttttc cttatcattt ttagcagttt cattcttagt aatgagcttc cttcttagct
    14761 tcgtgaaaca aataagttct catatgaaag ctttcgcctt aggtctttca ttttatgttc
    14821 tatatctact tttatttagt acatcttcga acatttatac agtactaatg agttatgttt
    14881 ttctagcgat aggtcagaca atgatgggga taatcgaaac caattatttt cagttgtcac
    14941 ttaacatgaa agaattacag aaactatata tttactcgga gaccttacat tctgtatttt
    15001 caggcattgc tgttttagta ataggaagtt ttgccttttt aagtagtcat cttgttttag
    15061 ttttcagaag tcttgctgtt tttgctctgt ttattcttct gtgttattgt gtgtttgtaa
    15121 acctcaaaaa actaagcatt gataagtaat atttataaat cagaaaacaa gcaaatgaga
    15181 tagttaattt ataaagtaga caaacgctat tttgagtgtt tgtctttttt tagtcaccta
    15241 gtctgccttt tttcacaaga ttgtctgaaa actgtgctat aatgataaca gaattgtgaa
    15301 ttgatgaaag tttgtgaaaa aacgagcaga ctttgacact ttgtgactta tacttgaaag
    15361 gaaagttggc tctaccattt tagggctaga aggactgtgt tcatgtcaga agaaaagcaa
    15421 ttgtatggtg cagatttagt ggttgatagt ttgatcaacc atgatgttga gtatgtcttt
    15481 gggattccag gcgcaaaaat cgatagggtt tttgatacct tggaagataa gggacctgaa
    15541 ttgattgttg cccgtcatga gcaaaatgct gcttttatgg ctcaaggtgt tggacgtatt
    15601 actgggaaac caggtgtagt attggtaaca tctggtccag gtgtctccaa tttggctact
    15661 ggtttggtaa cagcgacgga tgaaggagac cctgttcttg ctattggtgg tcaggttaag
    15721 cgtgcagatc tcttgaaacg tgcccaccaa tcaatgaata acgttgctat gcttgagcca
    15781 attaccaaat atgctgctga agtacatgat gctaacaccc tttctgaaac ggttgctaat
    15841 gcctatcgtc acgctaagtc agggaaacca ggtgcaagct tcatttcaat tcctcaagac
    15901 gtgacggatg ctccggtcag tgttaaggct attaagccta tgacagatcc aaaacttggt
    15961 tcagcatctg tttctgatat taactatcta gcacaagcca ttaaaaatgc agtgttgcca
    16021 gtctttcttt tggggaatgg tgcctcatca gaagccgtaa cttactctat tcgccaaatt
    16081 ttgaagcatg ttaaattgcc agttgttgaa actttccaag gtgccggtat cgtgtcacgt
    16141 gaccttgaag aagatacttt ctttggtcgt gtaggtcttt tccgtaacca acccggagac
    16201 atgttgctta aaaaatccga cttagttatt gccattggtt atgacccaat cgaatatgaa
    16261 gcacgtaact ggaatgctga aatttcagca cgtatcatcg ttattgatgt tgagccggcc
    16321 gaggtggaca cttacttcca accggaacgt gaattgattg gtaatgtaga agcgagctta
    16381 aacttgcttt tgcccgctat tcaaggttat aaattgcctg aaggttcggt tgaatatctt
    16441 aaaggtttga aaaacaatgt tgttgaggat gttaagtttg accgtcagcc tgatgaaggt
    16501 acggtgcatc cgctagattt aatcgaagtt ttgcaagaac aaacagatga tgatatgact
    16561 gttacggttg atgttggtag tcactatatt tggatggcac gttatttcaa atcgtatgaa
    16621 ccacgtcatt tgcttttctc aaatgggatg caaacgctag gtgttgctct tccatgggct
    16681 atctctgcag ctttggttcg tcctaagaca aaagtgattt ctgtttctgg tgatggtggt
    16741 ttcctcttct cagcacaaga attggaaaca gcagttcgtt tgaaattgcc aattgtccat
    16801 attatctgga acgatggtca ttacaatatg gtggaattcc aggaagaaat gaagtacggt
    16861 cgttcatctg gggttgactt tggtcctgta gattttgtaa aatatgctga gagctttgga
    16921 gccaaaggtt atcgtgcaac aagtaaagca gcgtttgcta gcttgcttca agaggctttg
    16981 actcaggctg tagatggacc agtccttatt gatgttccaa ttgactatag agataacatt
    17041 aaactcggcg aaactatttt gccagatgaa ttttactaaa aagagggtgt agacatgtct
    17101 gaagccataa aattatttca atataatact ttgggagcct tgatggctgg gctttatgga
    17161 ggtactttaa ctgttggaga gttgttagag catggagact tgggcctcgg aacattagat
    17221 tctatcgatg gtgagttgat tgttcttgac ggtaaagcct atcaagctaa aggctctgaa
    17281 ggtaaagtcg aagtggtaga agtctctcct gatgaaaaag ttccctatgc agcagtcgta
    17341 cctcaccaag ctgaagttat cttccgtcaa cgttatgaaa tgactgataa agaacttgag
    17401 gatcgtattg aatcatacta tgatggggtc aatcttttcc gttcaatcaa aatcaaaggt
    17461 cattttaaac acatgcacgt gcgcatgatt ccaaaatcaa atgcggacat taagtttgct
    17521 gatgttgcca ctcgccaacc tgagtatgag gtagatgata tttcaggtac aatcgttggt
    17581 atctggacac ctgaaatgtt ccacggtgtg agtgttgctg gttaccatct ccattttatt
    17641 tcagatgact tgacattcgg tggtcacgtt atggattttg ttatcgagaa tggtattatt
    17701 gaagttggac cagttgacca actcgatcaa cgcttcccag ttcaagaccg tcaatatctc
    17761 tttgctaaat tcaatgttga tgaaatgcgt aaagatatta ctaaggctga ataagcatat
    17821 aaataagata ctgtctcttt gtcaactgta gtgggtaacg aaaagctaac atctagagag
    17881 gaccggatag gtcctttttt atgtatgttc agtgtgatga agacacgctt cttaaagttg
    17941 ataaagtttc taaaaccgaa gcccaaacgt ttgatgtctt tgatcaactt attagtagct
    18001 ttaagtttcg cgtttgaata gtccgtttct agtgcgtttt tgatgtattg cttgtgtcta
    18061 agaaaagtcc taaagacagt ttgaaaataa tgattgacct tgctcctatt ttcctctatc
    18121 agttcaaaga actcatctac tctcttctcc tgaaagtgaa aaagcaaaag ctgataaagt
    18181 gtatagtagt cagtaagctc ttttgaaaag actagtgtct tcgcaacaac ttcatgtggt
    18241 gctaaagttt ggcggaaagt ctttgaataa aaagagttga gagatagttt acggctgtcc
    18301 ttttggaaga gtcgccagtg atttttcaag gctcgatagg gtagtgactt cttatcgaac
    18361 tggttcataa ttgcaattct tgtctttaaa aaggcacgtc caaggtgctg gatgatgtgg
    18421 aaacgatcaa gaacgatttt tgcgtttgga aagagcttgc gagccagtgg aatataagct
    18481 ccagacatat ccatcgtgat aaactgtacc tgttgtcgga ctttcaatgg atacttcaaa
    18541 aagtagtttc gtatagtagt ttggcggcga ttatcaagga tggttatgag ttcgtttgtc
    18601 tcataattct gcgccacaaa agccaattcc cctttcttga acccaaactc atcccaggac
    18661 ataacagcag ggagtttgtc ataatgttcc ttgaaagtga actgatcaag cttacgatag
    18721 acagtggacg tcgacacgcg aagtcttctt gcaatatcag ttagtgacac tttctcagtt
    18781 aggagttgtg taactttttg tcggactaga ttggagattt ggcagttttt ctcaacgata
    18841 gatgtctcag ctaccgtgac tcttctacaa cttttacact ggaaacgacg ttttttcaga
    18901 cgtagtagag ttggcgttcc cgcttgctcg agaagaggga ttttagaagg cttttgaaag
    18961 tcgtacttga tcatctttcc atggcaatga ggacatgatg gtgcagggta atcaagtttt
    19021 gcttgaatct cgatatgagt gtcagtttca aaaacaagtg aaatcttgat attttggtct
    19081 ttgattccga ttaattatgt ggtattctta ataagtctca taagttcttc ctaatgacgg
    19141 tttggttgct tttcattata gttctataat ccctacagta gttttaccca ctacagaaat
    19201 tatagagccc tatatattta atctataggt ggtttcttgg tgtagcagcg aaagattgta
    19261 attacttata tggggcatta ttatcattta tcaaaaaaga cctagagctt agctctaagt
    19321 caaaagtact attcacctac aaaggcattg atttctgctt cgatgttagc aattttttct
    19381 ttagcatccg cttcagtttc tccaactgtt gcaatgtaaa atttgatttt tggttctgta
    19441 cctgaaggac gaacggcaaa ccatgaatca tcagccaaga tgtatttcaa aacgttactt
    19501 ggaggagttg tcaatttttc tacgccgtca gcagtagtag ctgtttgttc caagaagtct
    19561 tctgttttag caatatcagt gttgttgaat tgtttaggag cattgcgacg gaatttgtcc
    19621 atgattttct tgatttctgc agcaccatca acacctgaaa gcgtaactga aattgtcttt
    19681 tctgagaagt aaccatattg tttgtagatt tcttcgatac catctgccaa tgtcatacca
    19741 cgtgaacggt agtatgcagc aatttctgca acgataagaa cggcttggat agcgtcttta
    19801 tcgcgtacaa atggtttgat gaggtaaccg aagctttctt caaaaccaaa catgtaagtg
    19861 taattgtgtt gtgtttcaaa ttcatgaatc ttttcaccga taaatttgaa gccagtcaag
    19921 acattaaaca ttgttgcacc gtagctttct gcaatcttag taactaattc agttgatacg
    19981 attgatttac aaagggcagc attagcaggg agagtaccag ctgttttgtg agcttcaagg
    20041 atatatttgg cgatgatagc accaatttgg ttaccagaaa ggttgaggta tgaaccatct
    20101 ggttgtcgga tttcaacgcc aagacggtcc gcgtcagggt cagttgcaac caatacgtcg
    20161 gcatctacat tacgaccgag ttcttcagca agagcaaagg catcttggtt ttctgggtta
    20221 ggagatttaa cagttaagaa gtcagcatga ggaaccgctt gagcttcaac gacttgaaca
    20281 gcatcaaacc cagcttgagc aagggcacgg cgagccaaca tttcaccagt accatgaagt
    20341 gaagtgtata caatcttcat gtcacgacca tactcattaa tcaagtcctg gttgatgtta
    20401 acgtctttaa cttcttttag gtattcagca tcaacatttt caccgatgat ttcgatgaga
    20461 ccgctagcct tgctgtcttc gaggtcagct aatttgacag tgaacggatt atcaatagca
    20521 cggatgtaat ctgtcaatgc atcggcatca gcgggtggca tttgtccacc gtcttcacca
    20581 taaactttgt atccgttaaa tggagctggg ttgtggctag cagttatcat gataccagca
    20641 aatgtgtgga gatgacgtac tgcgaatgat aattcaggag ttggacgaag actctcgaac
    20701 acataagatt taataccatg agctgctaaa acttgcgcag attcaaaagc aaactcagga
    20761 gagaaatgac ggctgtcata agcgatagca acaccacgtt ttttagcttc ctcacctttt
    20821 gagtcgatca attgcgccaa accttcggtt gcttgacgaa caacataaat gttaatacgg
    20881 ttggtaccag cgccaattaa accacgcata ccagctgtac cgaattcaag attagtatag
    20941 aaggcatctt ctttagtttt ttcatccata gaaaccaact catcacgaag ataagcaggc
    21001 aattcagcaa aatcgagcca tttttgataa ttttcagtgt aagacatatc aatctccttt
    21061 atatttttaa acgcttacat tatatcacaa ctaaaggaaa aaaatcatgc taattaccat
    21121 gttttttctt tattttttca atcgaagtag cataggtgtg atactaagcg ttaataggcc
    21181 agcaataacc atttcagcaa cagagtttat agtgaaaata gttgccatta gagtttttcc
    21241 acctgctgag tagaaattag ggattaggaa gtagatacct agaagcacga aaaatgtatt
    21301 tgtaaaagca cctaaaacac cagacagcat caagcctagg cgattttgaa gtaacttgta
    21361 gataaagtaa ggaaaaatac cgattaaaat acgaggaaca attgcaatga cagcagatgc
    21421 ccaagttcct ccttccacaa aaggactgaa gagataactg cctactgtat agacgatagt
    21481 gttacgaaca atactcataa tccccataaa accgcctaaa tatgcaccaa ttttaggacc
    21541 atagacgata ctagcaataa tgactgggat atgagttagg gttagtttga ttggaagtgc
    21601 aaaagcagca aagatagttt gactgagtac ctcaataacg accattgtgg ctattaatag
    21661 agccaattgt gccgttgggt ttgctttatt ttttttattc atcataaact tcttttcttg
    21721 tcaacaagac tattttgtta gagcattatc tattgactca ataatgacag aaatatcagc
    21781 tagagcgcca cgacctgtat ctccgcatgc aagtaaacca gattttggaa gaatttcttg
    21841 gtagccaact tcttgcaaga tttttaagtt cttcttagtc aatggatttt catacatttt
    21901 cgtattcatt gctggtgcaa ttagttttgg agtggtgctt ggcaaagcta aagccgtcgc
    21961 agttagcatg ttatcagcca tgccgtgtgc taatttggca atcgtatttg ctgaagctgg
    22021 agcaacaata aagagatcag ttttcttagc taagtcaata tgattaatac gttcagccaa
    22081 tttttcttcc ataacatcgg agtgaactgg attcttagaa agagcttgaa gagttagagg
    22141 cgtaataaag gattgagcag actcagtcat aatgacgtgg atatcatatc cctttttctt
    22201 tagtttgctt gttagatctg ctgacttata ggcggaaatt gagccagaaa cagcaagtat
    22261 gatacgttta gtcatagcat attctttcat ataaggcttg agcaattgca gacttagttg
    22321 taaccatctc ttcacccttt tcgtcaacta gataagcaat atgttgattt ggagtaatct
    22381 cacccaaatc atttgccaca ataatgtttg cttgattacg tttaagacta gcacgagcag
    22441 ccttgaaaag atcctctttg ctgacatttg cgagaagttt gaagccaacc aactgaatat
    22501 tgggattcca ttgtttaacc aggctaataa tctttggtgt ctttttaagg aaaagaacct
    22561 gataatccga agccgaagat atcttgctct cagtgttaga cttatgtaag agttggctgg
    22621 ggttttccgt atcttccaac tcagtgaaat ccgtcatata aattggagta tagtcagaga
    22681 tagccatact atggatgagg acatcatgct ccttgacaag tggctccata ctttttagga
    22741 gactgtctac gttggtaatt tctgtaatct ttagattttc ttttggttca ggtttaaccg
    22801 cagtctttac agttactaag gtaacttggt gacccttagc caagaaaagt tcagcgattt
    22861 ccttacccag ataacctgtt gaatgatttg tgattccacg gacatcatca atcttttcag
    22921 tggtaccacc tgatgtaatc aaaattttca tagtagtatt gtactaaaaa tttagatttt
    22981 agtaaataat agtaagtgtt tttgaaacgt gcccctataa aataaagtta taacttttta
    23041 tagctaaata aaaaccgaac atttgaaatc aatttataaa aaatagtgcg ttttttatta
    23101 atctttgtta taatagtaca tagaaatata tagaggagta tctcatgaga acagatattg
    23161 aaattgctca aagtgtagaa ttaaaaccaa tcacagaagt agttgaaaaa gttggaatcg
    23221 gctttgacga
//
