LOCUS       c00011_JAHBRO0..       13281 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  JAHBRO010000019.1 Streptococcus thermophilus strain Brie16
            Contig_19, whole genome shotgun sequence.
ACCESSION   JAHBRO010000019
VERSION     JAHBRO010000019
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 01:26:25
            Original ID  :: JAHBRO010000019.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13281
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13281
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[231:8281]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      232..8281
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..13281
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13281
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(232..486)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.6e-14,
                     bitscore: 46.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENLNTLDLETLASVEGGGCSWGGAGGATVQGAIGGAIGG
                     AFGGNVVLPVVGSVPGYLAGGVLGGAGGTVAYGATCWWS"
     CDS             complement(737..1138)
                     /locus_tag="ctg11_2"
                     /transl_table=11
                     /translation="MKLKNISSSVLRSFRTITAALAVFLISISLSLYKSKISPGTWLTV
                     GALAFVVIFVNGLLYRMLKKRPDSVNLLTIRQSFIVFPVITFLVLSVEFYTLLTFSDTT
                     DRIVLAVLMLLLILCDFLSYLQVKKYFKQ"
     CDS             complement(1468..1635)
                     /locus_tag="ctg11_3"
                     /transl_table=11
                     /translation="MFKNSKPYLLATILIVMGLANLFRSLDAVHHTINLLGLTVLLYSL
                     LFKKWVQFQK"
     CDS             complement(1993..2097)
                     /locus_tag="ctg11_4"
                     /transl_table=11
                     /translation="MAVMSFLDKPIMSFLEKHKATNSVKKKSSVKKKS"
     CDS             complement(2143..2373)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_5"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.2e-18,
                     bitscore: 60.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENFNTLDLETLASVEGGVCSWGGFAKQGVATGVGNGLRL
                     GIKTRTWQGAVAGAAGGAIVGGVGYGATCWW"
     CDS             complement(2729..2929)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_6"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.3e-08,
                     bitscore: 28.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNKQLERFKKLDTNALSNVSGQGYGAQCVIGTTGMTIVGAAFFG
                     IAGAGAGFAGGSTAFCYDTAK"
     CDS             complement(2948..3124)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_7"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.9e-11,
                     bitscore: 37.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENFNTLDLETLASVEGGLSCDEGMLAVGGLGAVGGPWGA
                     VGGVLVGAALYCF"
     CDS             3380..4117
                     /locus_tag="ctg11_8"
                     /transl_table=11
                     /translation="LKIYLLEDNSIQMGRLEEAVAHELKSFGKDLSCVQSFDKPDQLLS
                     AITSNTSDQIFFLDIEIKGEDKKGLDIAKIIRQNNPYAIIAFVTTHIEFMPQAFGVTAY
                     KYINKTLDEASFRKEIGETIAQVFPINATTTDEFFLYKTESQLINLPMDQILYLSTSDI
                     KHHVHLQTIHTLMDIRANLADFKKIHKKLYPCHRSYIVNTDMIISVNLTNYEATLINGQ
                     VLPVSRMKIGKIAQIVEERGRGC"
     CDS             4111..5451
                     /locus_tag="ctg11_9"
                     /transl_table=11
                     /translation="MLTTLWLLFLTLLSAGLEIILFLYLMGQKIRLRYFFLLLIFNLAF
                     NFIYNHSSWFIIKFWGEDIYYLLLSFLLSTKTKKPLKIKIFNGLFPDILNNLSLRLITF
                     FIFPFFNISITDYQSSLLISIPSSIAPLCLSFLFIKLFKGSFTILQKQKSNSPIQHIII
                     VANFFMFGYTLLLQILMYLENTTHSSTLELRKLCVVISLVLFFIMIVFLDRNIREMIQG
                     QLDFQKNLQLENLYTYNKHIEGLYNSVRSFRHDYSNLLVTLRLGIDKDDMDIVKEAYDS
                     VLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGME
                     TLDFIIVTSIFLDNAIEGAIQTQNPKITISFWEDHCSQLLSISNTISEEKTETKTIFER
                     GVSNKGRERGIGLANVTEILDNYINVNLETQSNNFSFTQQLTITKKA"
     CDS             complement(5469..5630)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_10"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.1e-08,
                     bitscore: 27.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANNTINNFETLDNHALEQVVGGSGWMDYINGFLKGFGGQRTLPT
                     KDYNIPQA"
     CDS             complement(5645..7012)
                     /locus_tag="ctg11_11"
                     /transl_table=11
                     /translation="MNPQLFKSTEFYHRRYHNMSTVLITPLILLVIFLFLFAFFAKKEV
                     TVTSRGSIEPTKVIAVIQSTSDNTIIDNQLVANKVVKKGDTLVQYSETMEASQKEGLQK
                     QLELLKRQESGLKTLQSSLTQGTNLFQEQEDEFGYQSTFNTYLSQAQDIDLGVAKTNTE
                     VNNQAAIASNTGSAIDNQISQLQTRVSEYEALSQAITNHETTLPEGNPHQATLNAYNSQ
                     YATTPDASVTDQYLSQVNTNISSLNASIGNLEIQKAGTGTVVTYDNSDSTKKEALKNQF
                     LQNAGQQLSSVETQINDTESKINQADVLLTNTLIQSPEDGILHLSQADKKATMAATGTE
                     LAQLYPDMTQTQEVAITYYVNSDYVPKLQKGQSVRLTLDKVGNHGTTIIGKLESIDNSA
                     TETERGNVFRVTARASISEKEAQNLRYGLEGRVTSVIDQKTYFNYFKDKLLNLQDQ"
     CDS             complement(7028..8281)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 262.4; E-value:
                     1.5e-79)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_12"
                     /sec_met_domain="TIGR01193 (E-value: 7.1e-193, bitscore:
                     635.8, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LIQNSNLFKLVLCSVPIYTLIVFAFMKPFERMNHDVMQSNAMVNS
                     AIIEDINGIETIKSLTSEEVCYQKIDGEFVDYLDNSFRLSKLSILQTSLKQGAQLILNV
                     LILWTGAQLVMGNTISIGQLITFNMLLSYFTNPLENIINLQTKLQSAKVANTRLNEVYL
                     IESEFGQSDDTYQEGIADGDITVTDLSYKYGFGRDTLTDVSLTIRQGEKISFVGVSGSG
                     KTTLAKMLVNFYQPYKGHIDFNGQNISRIDKKTLRQHINYLPQQSYIFSGSVLENLTLG
                     AARGITQADILKACEIAEIRQDIENMPMGFQTELSDGAGLSGGQKQRIALARALLTKSP
                     VLILDEATSGLDVLTEKQVIDNLLALKDKTIIFVAHRLSIAERTDRIVVIDHGRVVETG
                     SHQDLMSYPGFYYQLFRK"
     CDS             complement(8373..9182)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_13"
                     /sec_met_domain="Peptidase_C39 (E-value: 4.8e-46, bitscore:
                     148.9, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRFRRTFVPQIDMRDCGVAALASVAKYYGSDYSLAHLRELAKTN
                     KEGTTALGLVEAAKKIGFETRAIKAEMSLFEMEDVPYPFIAHVNKDGKLQHYYVIYKST
                     KDYLIIGDPDPSVKVTKMTKERFEKEWTGVTLFMRPEPSYKPHKDKKNGLWDFLPLIFK
                     QRSLIANIVFASLLVTLINILGSYYLQGILDEYVPNQMKSTLGIISIGLVVTYVLQQMM
                     TFARDYLLTILSQRLTIDVILSYIRHIFELPMSFFCHKTYRGGYLTF"
     CDS             complement(10196..11941)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     289; E-value: 4.3e-88)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 314.8; E-value: 2e-95)"
                     /gene_kind="transport"
                     /locus_tag="ctg11_14"
                     /transl_table=11
                     /translation="MPNQNQWSVFKRLLTYLKPYKFLTFLALTFLLSTTVIKSIIPLVA
                     SYFIDHYLHDMNQAASMILIGYYGLYLLQTLVQYLGNLFFARVSYSIVRDIRRDAFANM
                     EKLGMSYFDKTPAGSIVSRLTNDTETISEMFSGTLSSFISAIFIFVTTLYTMMILDIRL
                     TGLIVLFLPLIVLLVNLYRKKSVAIIEKTRALLSDINAKLSESIEGIHIIQAFNQEKRL
                     KKEFDAINEEHLIYAIRSISLDSLFLRPAMSLLKLLAYAVLMAYFGYRGIYLGITAGTM
                     YAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPEQRDTAAKVTEGNI
                     RFENVSFSYDGKHQILDNISFSVNKGETIAFVGSTGSGKSSIINVLMRFYEFQSGRVLI
                     DGVDIRDYSQAELRKNIGLVLQDPFLYHGTIKSNIAMYQDLTDEEIKAAAEFVDANHFI
                     DKLPEGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANIDSETEAIVQNS
                     LAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIEHGSHEELLALGGTYHKMYSLQAG
                     TMEGE"
ORIGIN
        1 acatctattt ttacaatcat caacgttttc aagagcgcaa taacggcctt gcccctcttg
       61 aaatgaggaa caaggccgtc gcctaatatt ttattatttc attgtccact tgacagggag
      121 ctattcaata tatgttcaag attatttttt atgtttattt ttattgacct ttttgaaaaa
      181 gatattacct aacaaagcaa caacaaaacc tataataaaa tataccatag attagctcca
      241 ccagcaggtt gctccatagg caacagtacc acctgcacca cctagaacac caccagctag
      301 ataaccagga actgagccta caactggtaa aactacatta cctccaaacg ctcctccgat
      361 agctcctccg atagctcctt gaacagtcgc tccacctgcg cctccccagc tacatccacc
      421 accttcaaca ctagcaagtg tttcgaggtc aagggtgtta aggttttcaa ttgtttgagt
      481 tgccatggca actaccccct aaaattttta tcgtgtgatc tctcaatcac atctttagta
      541 tagcattcaa gtgtctctat cagagctagc gtcccaaaaa gtggctatat gtcccgaatg
      601 gtaattccta aagaacatcc ttcaatcatt ggaaatcttc ctctaatttt cacatattta
      661 cttaatcact ttcttattat aacactttta tgcaaatatc ttatagattg cttacagaat
      721 aatcaagcaa atgcgtttat tgtttaaaat attttttgac ttgaaggtaa gatagaaaat
      781 cacagaggat taacaaaagc attaatacgg ctagtactat acggtctgtg gtatcactga
      841 atgttagtaa tgtgtaaaac tctacactaa gcactagaaa tgtgatgaca ggaaagacaa
      901 tgaaggactg ccgtattgtt aacagattta ctgaatctgg acgcttctta agcatacggt
      961 agagcagtcc attaacaaaa atgactacga aagctagtgc tccgactgtt agccaagttc
     1021 ctggcgagat cttgcttttg tagagagaaa ggctgatact tataaggaaa actgccaacg
     1081 cagcagtgat ggttctaaaa gatcgcaata cactcgaact aatattcttt aacttcatga
     1141 taaaacacct aaactatgaa taacctcagt cagtcttgca aacctaataa gctattacat
     1201 ttaactctat tcctctctgt attttattat acagctgtaa gatttcaagt aagcccttag
     1261 cgattaaatt ctactggaga tgtaatacag tagtgtcatt agtactgata ctttaaatag
     1321 gcgaatatac atatctttgt tttctctatt acaaagatat gcaatcaaat ataatataat
     1381 ctccgctatc attagcaaga ataattttac ttcgggaaca tcaaaaataa gcatttgcaa
     1441 gcatcttacg ttcaaagtga ccaaaggtta cttttgaaac tgtacccact ttttaaaaag
     1501 taagctataa agaagcaccg ttagccctag caagttaatg gtatggtgaa ctgcatccaa
     1561 gcttctaaat agattagcga ggcccattac gatgagaatg gtagccagta aatacggttt
     1621 tgagttttta aacatacttt tctccttaaa gtgtttttag ctagtctgtg cataatctat
     1681 gaattttatt atagattgga agccgataaa aaagtagtga cataaatgtc actacttgtc
     1741 tgaccttata tccttgataa ccgtacacat aagaaagaga aataaacata acccgataag
     1801 atttaggcat tgaagtccaa aattcagttt ttctccaaag ttatgtaagg caacaaggac
     1861 gaagcccata gacatcatta gagacactag gcgttttttg gtcatgatta caaataactc
     1921 ttctcttata tcgaaatttt caatcataat tcacatgcta ttcacagacc agcaattgac
     1981 aagacatttc agttaggatt tcttcttaac ggaagatttc ttcttaacgg aattggtagc
     2041 cttgtgtttt tcaagaaatg acataattgg cttatctaaa aaactcataa cagccatgga
     2101 aaccatccct aaaatataac ttttcaaatc aaacataatc catcaccacc agcatgttgc
     2161 tccataacca acaccaccta cgatagcacc tccagctgct cctgcgacag caccttgcca
     2221 agtacgtgtt ttgataccta gtcgtaaacc attaccaact cctgtagcta ctccttgttt
     2281 agcaaaacct ccccagctac atacaccacc ttcaacacta gcaagtgttt cgaggtcaag
     2341 ggtgttaaag ttttcaattg tttgagttgc catggcaact acctcctaaa atttttatcg
     2401 tgtgatctct caatcacatc tttagtatag catacaagtg tctctatcag agctagcgtc
     2461 ccaaaaagtg gctatatgtc ccgagtagta aaaaaaagac tgaatatcat ttttgattca
     2521 gtccatgtct tattgaaaaa gctttaacta attctttcta tactgcctat agactccaaa
     2581 taaaaagaaa aagaatccta ttgatgctaa caaaagttga tagatatttc ctgatgacaa
     2641 tagtactttg ctatataaat atatcatcgc aatagtcgaa aaaatgatta ggtatttctt
     2701 catttgtatc acctatctca aatgaagatt atttagctgt atcataacaa aatgctgtgc
     2761 taccgcctgc aaatccagct cctgcacctg cgatgccaaa gaaagctgca ccgacaatcg
     2821 tcattccggt agtaccaata acacattgag caccatagcc ttgaccactt acattagaca
     2881 atgcatttgt atccagtttt ttaaatcttt caagttgttt attattcata aattcctccc
     2941 atacaaatta gaaacagtat aaggctgcac ctactaacac cccaccgaca gctccccacg
     3001 ggccacctac tgcaccaagt cctcctactg ccagcatccc ctcatcacag gacaacccac
     3061 cctcaacact agcaagtgtt tcgaggtcga gggtgttaaa gttttcaatt gtttgagttg
     3121 ccatggcaac tacctcctaa aatttttatc gtgtgatctc tcaatcacat ctttagtata
     3181 gcattcaagt gtctctatca gagctagcgt cccaaaaagt ggctatatgt cccgaatggt
     3241 aattcctaat gtatattatt tctaaaattc agaaaaaaaa aaaaatctca ttttatactc
     3301 ataaaaaatt gaaaaaccgt tttctttatg ttacaatttt tcaataaaca gtattcgtca
     3361 taaaagagag gactagacct tgaagattta cctattagaa gataattcta ttcagatggg
     3421 tcgcttggaa gaggctgtgg cacatgaact taaatccttc ggaaaagatc tatcttgtgt
     3481 ccagtctttt gacaaacctg accagttgtt atcagctatc acttctaata caagcgatca
     3541 gattttcttt cttgatattg aaattaaagg tgaagataag aagggacttg atatcgctaa
     3601 aatcatacgt caaaataacc cttatgctat cattgccttt gtcactacac atatagagtt
     3661 catgcctcaa gcttttggcg ttacagccta taaatacatc aataaaacct tagatgaagc
     3721 tagctttaga aaagaaatag gggaaaccat tgctcaagtc ttccctatta acgcaactac
     3781 cacggatgag ttttttctct acaaaacaga gtctcaatta ataaaccttc ctatggatca
     3841 aattctatac ctatccacat cagatatcaa acaccatgtt cacctccaga ctatccatac
     3901 cctcatggat atccgagcaa atctggcaga ctttaaaaag atacacaaaa agctctaccc
     3961 atgccatcgg tcctatatcg tcaatacaga tatgattatc tctgtcaact tgaccaatta
     4021 tgaagctacc ttaattaatg gtcaagtcct accagtatcc cgtatgaaga taggaaagat
     4081 tgcacagatt gttgaggaaa gaggcagagg atgttaacaa cgttatggct actttttctc
     4141 acccttttaa gtgcaggcct agaaattatt cttttccttt atttaatggg acagaagatt
     4201 cgtctgaggt attttttcct actccttatt tttaatttag cctttaattt tatttataac
     4261 cactcttctt ggtttatcat taaattctgg ggtgaggata tctattatct tcttctctcc
     4321 ttccttttat ccactaagac taaaaaacca ttaaaaataa agattttcaa tggtctcttc
     4381 cctgatatcc tcaacaacct tagtttaaga ttgattactt tctttatctt cccttttttt
     4441 aatattagta tcaccgatta tcaaagctct ctattaatat ccatcccttc atctattgca
     4501 cctctttgtc tatcatttct ctttattaaa ttattcaagg ggagttttac catacttcaa
     4561 aagcagaaat caaattctcc gattcaacat attattatag ttgctaactt ttttatgttt
     4621 gggtacaccc tactgttaca gatcctcatg tatcttgaaa acactactca ttcttcaact
     4681 ttggagcttc gaaaactctg tgttgttatt tcacttgtcc tcttcttcat tatgattgtc
     4741 tttttagaca gaaacattcg tgaaatgatt caaggacaat tggacttcca aaaaaatctc
     4801 cagctagaaa atctctacac ctacaataaa catattgaag gtctctacaa ttctgttcgt
     4861 agttttagac acgattatag taatctctta gtcacattac gattggggat agataaagac
     4921 gatatggata ttgtcaaaga agcctatgat agtgtgcttc aagaatccga taaacgatta
     4981 aatacaagaa actttgactt agctagactc gttaatattc aggataacac tttgaaaagc
     5041 cttctgtccg caaaagttct acaagcagaa gaagaaggca ttgaagctca gattagcatc
     5101 ccagaaccca tccacttgat tgggatggag actctggact tcattatcgt cacttctatt
     5161 tttttagata acgctattga aggtgccatt caaactcaaa accctaaaat tactattagc
     5221 ttttgggaag atcattgttc acagctatta tctattagca ataccataag tgaagaaaaa
     5281 acagaaacca aaaccatatt tgaaagaggt gtctccaaca agggacgaga gcgaggcatt
     5341 ggccttgcta atgtcacaga aatcttagat aactatatca atgtaaactt agaaacacag
     5401 agtaacaatt tctcattcac acaacaatta acaataacta aaaaggccta acagcctttt
     5461 ttctatacct aagcttgagg aatgttatag tcttttgttg gaagcgttct ttgccctccg
     5521 aatcctttta ggaaaccatt tatataatcc atccacccac ttccacctac gacttgttca
     5581 agagcgtggt tatcaagtgt ttcaaagtta ttaatcgtat tgttagccat cagtaattct
     5641 cctcctattg gtcttgcaag tttagtaact tgtctttaaa gtaattgaag taggtctttt
     5701 ggtcaataac gcttgtcaca cgaccttcta gaccgtaacg tagattttgg gcttcttttt
     5761 ctgaaatact tgccctagca gttactctaa acacattccc cctttctgtt tccgtggcag
     5821 aattatcaat actctcaagt tttccaataa ttgtggtacc gtgattacca accttatcca
     5881 aggtcagtcg aactgactgg cctttttgca gttttggcac ataatccgaa ttcacataat
     5941 aagtaatggc aacttcctgg gtttgagtca tatcgggata aagctgggcc aactcagttc
     6001 ctgtcgcagc catggttgct tttttatcag cttgactcaa gtgtaagatt ccatcttctg
     6061 gtgactggat gagggtatta gtcagaagga catctgcctg attgatttta ctctcggtat
     6121 cgttaatttg tgtttccact gagctcaatt gctgtcctgc attttgcaag aattgatttt
     6181 ttagagcttc ttttttagtg ctatcactat tgtcataagt tacaactgtg cctgtcccag
     6241 ccttttggat ttctagatta cctatggaag cattcaagct cgaaatattg gtattaactt
     6301 gagataggta ttggtctgtt acactggcat ccggtgtcgt agcatactga ctgttatagg
     6361 catttaaggt tgcctgatga ggattgcctt caggtaaagt cgtttcatga ttggtaatag
     6421 cttgagagag cgcctcatac tctgagaccc gagtctgcaa ttgactaatc tggttatcaa
     6481 tagcagaacc ggtattactc gcaattgctg cttggttatt aacctctgta tttgttttag
     6541 ccacacccaa gtcaatatcc tgtgcctgac ttaggtaggt gttaaaagta ctctgataac
     6601 caaactcgtc ttcctgttct tggaaaagat tggttccctg cgttaggcta gattgcaagg
     6661 tcttcaaacc tgattcctgt ctttttaaaa gttctagttg cttttgaagc ccctcttttt
     6721 gcgatgcctc catggtctct gaatactgaa ctaaggtgtc ccctttttta acaaccttat
     6781 tagcaaccag ttgattatct atgatggtat tgtcactggt tgattggatt actgcgataa
     6841 ccttggttgg ctctatactt cctctagacg tgactgtaac ttccttctta gcaaaaaaag
     6901 cgaaaagaaa aaggaaaata actaacaaaa tcaagggagt aatcaaaaca gtagacatat
     6961 tgtggtagcg acgatggtaa aactctgtgc ttttaaacaa ctgtggattc atcgtgtttc
     7021 cttttcctca ctttctaaat aattgataat agaaacctgg ataagacatt aggtcttgat
     7081 gagaacctgt ctccactacg cgtccgtgat caatgactac gatacggtcg gtccgctcag
     7141 cgatactaag cctgtgtgct acaaagatga tcgttttatc ttttagtgct aggaggttat
     7201 caataacctg cttttctgtc aaaacatcca atccgctagt tgcttcatct aagattagta
     7261 caggagattt cgttagtagt gcacgcgcca aagcgatacg ttgcttttgc cctccagaca
     7321 gacctgctcc atcagacagc tctgtctgaa accccatagg catgttttca atatcttgac
     7381 gaatttctgc tatttcacaa gctttcaaaa tatcagcttg cgtaataccc cgtgctgcac
     7441 ctaaagtaag attttctaaa acactaccac taaatatata ggattgctga gggagatagt
     7501 taatatgttg acgaagagtt ttcttgtcta tgcgactaat attttgacca ttaaaatcta
     7561 tgtgcccctt atatggttga taaaaattga ccaacatttt agctagagta gtcttaccag
     7621 atccactgac accaacaaaa ctgatttttt ctccttgtct aatcgtcaaa ctgacatcag
     7681 tcaaagtatc acgaccaaaa ccatatttat aagataaatc cgtaacagtg atatctccat
     7741 ccgcaatgcc ttcttgatag gtatcatcac tttgtccaaa ctctgattca atcagataga
     7801 cctcattgag cctagtatta gctaccttag cagactgtaa cttggtttgc aggttaatga
     7861 tattttccaa aggattcgtg aagtaggaaa gcaacatatt aaaagtaatc aattgtccta
     7921 tcgaaatggt atttcccatc accaactgag cacctgtcca gaggataagt acatttaaaa
     7981 taagttgagc accttgtttc aatgatgttt gtagtataga taacttagaa aggcgaaaag
     8041 aattgtctag atagtcaaca aactcaccat caatcttttg atagcatact tcttcgctgg
     8101 ttagtgactt tatggtttca atcccattaa tgtcctcaat gatggctgaa ttaaccatag
     8161 cattactctg catgacgtca tgattcattc gctcaaaagg tttcataaag gcaaagacga
     8221 taagggtata aattggaacc gaacaaagaa ctagcttgaa gagattgcta ttttgtatca
     8281 ataacacgcc tcgtacgata atcacaatag agaaatcaag gaaaagtgat aatatcgtcg
     8341 aagccagagc atcgataata gagttagcat cactaaaacg tgagataacc tcccctgtac
     8401 gtcttgtggc aaaaaaaaga cattgggagt tcaaagatat gtcgtatgta ggacaagata
     8461 acgtcaatgg tcaatcgctg actcagtatg gttaagagat aatctcttgc aaaagtcatc
     8521 atttgttgta aaacataggt cacaactaat ccaattgaga taattcctaa ggtagacttc
     8581 atttgattag ggacatattc gtctagaata ccttgtaaat aataggaacc taaaatattt
     8641 attaaagtaa ccaagagact ggcaaagaca atattagcta tcaaggacct ttgtttaaag
     8701 atcaaaggga gaaagtccca gagtccattt ttcttatcct tatgtggttt ataactgggt
     8761 tccggtctca taaaaagagt aacacctgtc cactctttct caaaacgctc tttagtcatt
     8821 ttagttactt ttacacttgg atcagggtct ccaattatca gataatcctt ggtgctttta
     8881 taaataacat aataatgttg aagcttccca tctttattaa catgagcaat aaaaggataa
     8941 ggaacatctt ccatctcaaa gagcgacatt tcagccttta tagctctcgt ttcaaagcca
     9001 atttttttag cagcctctac aagacctaag gcagttgtcc cttctttatt ggtcttcgcc
     9061 aactcacgca gatgtgctaa tgaataatct gaaccatagt acttggccac tgatgccaag
     9121 gcagcaactc cacaatccct catgtctatt tgagggacaa aagtcctacg aaaacgaaac
     9181 ataccaaacc ctttcatcac aaattatcat atgattagta tgtcatattt tcaggataaa
     9241 aagagccagc gtcccaaaaa gttgccatac gtcccaaacg gtaagaaaaa tcttaaagtc
     9301 atctccacta ttaccattta agccgtattt ggggtcattt aggacaagtt cattgaaatc
     9361 gatttcaaag ttatacaata gttattagaa ggaaacattc taaaatagtc ctacaagcat
     9421 acgtatttga tctaaccatt attactgtgc cagccctggt atttccaaag gaaaccatga
     9481 ctgctgatag cctcggagcc tatctctatc gtatgatgtc ataatttgat tatttttatt
     9541 ccgaaaaggg ataacattat gaaaaacgtc aatccatatc tcaaaaaatc ctatcaaaaa
     9601 aggctaaatc agcctcttga gattcgatta ctcaattatc ggtttaattt tccttagctt
     9661 tgtaagtgta tttgttatca ctgtcaatgc tatttttagc gtcactagag gggttccctt
     9721 ccttaatgcc caccttattt ccaccttgag taattgtgcc ttctatcttt tgatttactc
     9781 aaccttgagg tggcaccatc tcaaaaagct ctataatctc tacagtggtt tttcccacta
     9841 cagaaattat agagccgaag ttaagtagtt ctgtggtaaa ctgagtcata ggaataaatc
     9901 tctttctagt aatgttttgc aactctacta taacggattt attccttttt gtgtttacac
     9961 aacttatttt acactacctc aacgtttgca agtacctcga gatcgagtgt ttcaaatgta
    10021 ttatttgttt gccttgtcat tctaacaacc tcctaaatta tttttagctt tttctctcaa
    10081 gctatgattt tattataggg tggtagccaa caaaaaagta gtgacataaa tgtcactact
    10141 cgattttgat ttttaagaaa tcttttcgaa tatagaagct atggtctaga ttagcttact
    10201 ctccttccat ggtgcctgct tgtaggctgt acatcttgtg ataggtgccg ccgagggcta
    10261 ggagctcttc gtggctaccg tgttcaatga tgcggccctt gtctaagaca tagatgcagt
    10321 tagcatcttg gattgttgat aggcggtggg caatggcaat ggttgtacgg ccttgacgca
    10381 tttttgcaag agagttttga acaatagcct ctgtctccga atcaatattg gctgtcgctt
    10441 catccaaaat caagatttta ggctggctag caacggttct agcaaaggct agaagctggc
    10501 gttgaccggt tgagaaactt gaaccacgtt cggaaactgg ggaatcatag ccttcaggaa
    10561 gtttatcaat aaagtgattg gcatcgacaa actcagcagc agctttaatc tcttcatcag
    10621 ttaaatcttg atacatggca atattggatt tgattgtgcc atgatagagg aaggggtcct
    10681 gaaggacaag accaatattc ttgcgcagct ctgcctgact ataatcacga atatccacac
    10741 cgtctatgag aactcgtcct gattggaatt catagaatcg catgagcacg ttgataatag
    10801 aggattttcc agagcctgta gatcccacaa aggcgatggt ttcaccttta ttgacagaga
    10861 aggaaatatt atccaaaatc tggtgcttgc catcatagga gaaggagaca ttctcaaagc
    10921 gaatattccc ctcagtaacc ttggcagctg tgtctctctg ttcaggctca taggtacgct
    10981 cgtcaatcaa ggcaaagacc cgacctgctg agaccataga ggtttgtaga gtcgagaagt
    11041 tttgtgtcac ttcaatcaag ggatcaaaga ggcgattaat atactggata aaggcataca
    11101 tggtacctgc tgtgataccc agatagatac ctcggtagcc aaaataggcc atgagaacag
    11161 cataagccag gagcttcagt agactcatgg ctgggcgtag aaagagagaa tccagtgata
    11221 tagaacggat ggcataaatc aggtgttcct cattaatggc atcaaactct tttttaagac
    11281 gcttctcctg gttaaaggcc tgaatgatgt gaatcccttc gatactctct gacagtttgg
    11341 catttatatc tgaaagcaag gctctggtct tttcaatgat ggccactgat tttttgcgat
    11401 aaaggttaac caaaaggaca atcagaggaa gaaagaggac aataagcccg gtcagacgaa
    11461 tgtccaagat catcatggtg taaagggtgg taacaaagat aaagatagcc gaaataaaac
    11521 tagacagagt tcctgagaac atctcgctaa tggtctcagt atcattggtc aagcgggaaa
    11581 cgatggaacc tgctggggtc ttgtcaaagt aagacatacc cagtttttcc atattggcaa
    11641 aggcatctcg acgaatatct ctgacaatgc tataggacac acgcgcaaag aagagatttc
    11701 ccagatactg gactagtgtc tgcaagaggt agagaccata gtagccaatc agaatcatac
    11761 ttgccgcctg attcatatca tgaagatagt gatcaataaa ataagaggcc accaagggaa
    11821 tgatactctt gataaccgtt gtggacaaga ggaaggtcaa agctagaaag gtcaagaact
    11881 tgtaaggctt gagataggtc aagagacgct taaacacaga ccattggttt tgattaggca
    11941 tgagcttctc ctccttccat ttctaactgt tgagactcat aggtcttggc ataccaacca
    12001 ccttgagcta gtaagtcgtc atgacgccca cgttcaatga tacgaccatc ttgcatgacc
    12061 aggatgaggt cagcgtgcac caccgcactg agacggtggg cggtaataat agttgttttg
    12121 tccttgcgag tatgcttaag attatcaata atggcatgtt ctgtcttagc atcaaccgca
    12181 gataaggagt catccaaaat caaaatttct ggattcaaaa tcatggcccg gctcatagcc
    12241 agacgttgtt tttgaccacc tgataggctg acaccctttt caccaatgat tgtttcaaag
    12301 ccttcaggca tatccttgat atcatcataa acttgagcta acttagtcgc ttcttccacc
    12361 ttatcaatgg agaaatctgg attaccaaag cggatattgt ctaaaataga actggcaaag
    12421 agaaactggt cttgaggaac ataaccaatc aagctacgca agtctgatag gcgatagtct
    12481 cggatgtcat gtccattcaa atagatggct ccttgattga catcgtgctc ccgcaagagc
    12541 aacttgacaa gagccgtctt tcctgagcca gtcggtccaa ccaaaccaag ggtttgcccc
    12601 ttgtccaagg tgaaatgaat atctcgcaaa gtatcctcat cctcaaaagc aaagcggtca
    12661 atcgcaaagt ctaaacgacc attttcaatg cttggaagag gataagcggg atcttgaaca
    12721 tctgattcct gctctaaaag agtctcgata cgttggtagg acacatttcc cctctgcgtg
    12781 atattaaaga ggaagccaat ggccattagg ggccaaacca gcatgtccaa ataggtaata
    12841 aaggttacca aatttccgac cgttatctga ccggcctgaa tcataaaggc cccgacaagg
    12901 agggtcaaaa cataagatga gccaacaaag agcaagacca aaggatcaaa aaggctgtca
    12961 tacttcatgg tatgcatatt cttttcaaaa gtcatcttat tggtctcttg gaaggactgg
    13021 agctcagcct cctgatagcc aaaagacttg gttaccttga tacctgacac cgattcttgt
    13081 accttattat taagttcaga aaaagctgcc tgggattctc caaaagcttt gtgggtctta
    13141 cgtcccaaac gactagtcgc aaaagccatg aaaggtagag gtaagactgc catcagggtc
    13201 atctgccagg aaatgctgaa gaacatggtg attaaagtca ccaaggctgt gatagacgca
    13261 tccacggctg acatgacacc c
//
